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 An investigation of the effects of endometriosis on the proteome of human
eutopic endometrium: a heterogeneous tissue with a complex disease.
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2:  Zhou D, Qin L, Han Y, Qiu J, Chen Z, Li B, Song Y, Wang J, Guo Z, Zhai J, Du
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 Global analysis of iron assimilation and fur regulation in Yersinia pestis.
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3:  Giovannetti E, Del Tacca M, Mey V, Funel N, Nannizzi S, Ricci S, Orlandini
C, Boggi U, Campani D, Del Chiaro M, Iannopollo M, Bevilacqua G, Mosca F, Danesi
R. 
 Transcription analysis of human equilibrative nucleoside transporter-1 predicts
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Cancer Res. 2006 Apr 1;66(7):3928-35. 
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4:  Shao J, Zhou B, Di Bilio AJ, Zhu L, Wang T, Qi C, Shih J, Yen Y. 
 A Ferrous-Triapine complex mediates formation of reactive oxygen species that
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Mol Cancer Ther. 2006 Mar;5(3):586-92. 
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5:  Graham DJ, Stahlhut M, Flores O, Olsen DB, Hazuda DJ, Lafemina RL, Ludmerer
SW. 
 A genotype 2b NS5B polymerase with novel substitutions supports replication of
a chimeric HCV 1b:2b replicon containing a genotype 1b NS3-5A background.
Antiviral Res. 2006 Jan;69(1):24-30. Epub 2005 Nov 4. 
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6:  Han WG, Liu T, Lovell T, Noodleman L. 
 Active site structure of class I ribonucleotide reductase intermediate X: a
density functional theory analysis of structure, energetics, and spectroscopy.
J Am Chem Soc. 2005 Nov 16;127(45):15778-90. 
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7:  Liu X, Zhou B, Xue L, Shih J, Tye K, Qi C, Yen Y. 
 The ribonucleotide reductase subunit M2B subcellular localization and
functional importance for DNA replication in physiological growth of KB cells.
Biochem Pharmacol. 2005 Nov 1;70(9):1288-97. 
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8:  Cui JQ, Shi YF, Zhou HJ, Li JQ. 
 [Changes in gene expression profiles of hydatidiform mole and choriocarcinoma
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Zhonghua Zhong Liu Za Zhi. 2004 Dec;26(12):727-31. Chinese. 
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9:  Alberty RA. 
 Thermodynamic properties of nucleotide reductase reactions.
Biochemistry. 2004 Aug 3;43(30):9840-5. 
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10:  Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. 
 Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine
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Clin Cancer Res. 2004 Apr 1;10(7):2307-18. 
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11:  Moosavi-Movahedi AA, Hakimelahi S, Chamani J, Khodarahmi GA, Hassanzadeh F,
Luo FT, Ly TW, Shia KS, Yen CF, Jain ML, Kulatheeswaran R, Xue C, Pasdar M,
Hakimelahi GH. 
 Design, synthesis, and anticancer activity of phosphonic acid diphosphate
derivative of adenine-containing butenolide and its water-soluble derivatives of
paclitaxel with high antitumor activity.
Bioorg Med Chem. 2003 Oct 1;11(20):4303-13. 
PMID: 13129566 [PubMed - indexed for MEDLINE]

12:  Juhasz A, Frankel P, Cheng C, Rivera H, Vishwanath R, Chiu A, Margolin K,
Yen Y, Newman EM, Synold T, Wilczynski S, Lenz HJ, Gandara D, Albain KS,
Longmate J, Doroshow JH. 
 Quantification of chemotherapeutic target gene mRNA expression in human breast
cancer biopsies: comparison of real-time reverse transcription-PCR vs. relative
quantification reverse transcription-PCR utilizing DNA sequencer analysis of PCR
products.
J Clin Lab Anal. 2003;17(5):184-94. 
PMID: 12938148 [PubMed - indexed for MEDLINE]

13:  Huebener N, Lange B, Lemmel C, Rammensee HG, Strandsby A, Wenkel J, Jikai
J, Zeng Y, Gaedicke G, Lode HN. 
 Vaccination with minigenes encoding for novel 'self' antigens are effective in
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Cancer Lett. 2003 Jul 18;197(1-2):211-7. 
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14:  Zhou B, Yen Y. 
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Cytogenet Cell Genet. 2001;95(1-2):52-9. 
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15:  Zhou B, Mo X, Liu X, Qiu W, Yen Y. 
 Human ribonucleotide reductase M2 subunit gene amplification and
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Cytogenet Cell Genet. 2001;95(1-2):34-42. 
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16:  Mesyanzhinov VV, Robben J, Grymonprez B, Kostyuchenko VA, Bourkaltseva MV,
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 The genome of bacteriophage phiKZ of Pseudomonas aeruginosa.
J Mol Biol. 2002 Mar 15;317(1):1-19. 
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17:  Wnuk SF, Chowdhury SM, Garcia PI Jr, Robins MJ. 
 Stereodefined synthesis of O3'-labeled uracil nucleosides.
3'-[(17)O]-2'-Azido-2'-deoxyuridine 5'-diphosphate as a probe for the mechanism
of inactivation of ribonucleotide reductases.
J Org Chem. 2002 Mar 22;67(6):1816-9. 
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18:  Hughes AL. 
 Origin and evolution of viral interleukin-10 and other DNA virus genes with
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J Mol Evol. 2002 Jan;54(1):90-101. 
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19:  Jakob NJ, Muller K, Bahr U, Darai G. 
 Analysis of the first complete DNA sequence of an invertebrate iridovirus:
coding strategy of the genome of Chilo iridescent virus.
Virology. 2001 Jul 20;286(1):182-96. 
PMID: 11448171 [PubMed - indexed for MEDLINE]

20:  Karlsson A, Helou K, Walentinsson A, Hedrich HJ, Szpirer C, Levan G. 
 Amplification of Mycn, Ddx1, Rrm2, and Odc1 in rat uterine endometrial
carcinomas.
Genes Chromosomes Cancer. 2001 Aug;31(4):345-56. 
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21:  Skamrov A, Feoktistova E, Goldman M, Beabealashvilli R. 
 Gene re-arrangement and fusion in Mycoplasma gallisepticum thyA-nrdFEI locus.
FEMS Microbiol Lett. 2001 Jun 12;200(1):31-5. 
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22:  Erickson HK. 
 Formation of the cystine between cysteine 225 and cysteine 462 from
ribonucleoside diphosphate reductase is kinetically competent.
Biochemistry. 2000 Aug 8;39(31):9241-50. 
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23:  Coucke PA, Decosterd LA, Li YX, Cottin E, Chen X, Sun LQ, Stern S, Paschoud
N, Denekamp J. 
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(E)-2'-deoxy-(fluoromethylene)cytidine as a cytotoxic radiosensitizer in vitro.
Cancer Res. 1999 Oct 15;59(20):5219-26. 
PMID: 10537300 [PubMed - indexed for MEDLINE]

24:  Masuda N, Negoro S, Takeda K, Takifuji N, Hirashima T, Yana T, Kurata N,
Kuwabara T, Kobayashi S, Kudoh S, Matsui K, Takada M, Fukuoka M. 
 Phase I and pharmacologic study of oral (E)-2'-deoxy-2'-(fluoromethylene)
cytidine: on a daily x 5-day schedule.
Invest New Drugs. 1998-1999;16(3):245-54. 
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25:  Rieger J, Durka S, Streffer J, Dichgans J, Weller M. 
 Gemcitabine cytotoxicity of human malignant glioma cells: modulation by
antioxidants, BCL-2 and dexamethasone.
Eur J Pharmacol. 1999 Jan 22;365(2-3):301-8. 
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26:  Sarel S, Fizames C, Lavelle F, Avramovici-Grisaru S. 
 Domain-structured N1,N2-derivatized hydrazines as inhibitors of ribonucleoside
diphosphate reductase: redox-cycling considerations.
J Med Chem. 1999 Jan 28;42(2):242-8. 
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27:  Hamann CS, Lentainge S, Li LS, Salem JS, Yang FD, Cooperman BS. 
 Chimeric small subunit inhibitors of mammalian ribonucleotide reductase: a dual
function for the R2 C-terminus?
Protein Eng. 1998 Mar;11(3):219-24. 
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28:  Lye LF, Hsieh YH, Su KE, Lee ST. 
 Cloning and functional analysis of the ribonucleotide reductase gene small
subunit from hydroxyurea-resistant Leishmania mexicana amazonensis.
Mol Biochem Parasitol. 1997 Dec 1;90(1):353-8. No abstract available. 
PMID: 9497060 [PubMed - indexed for MEDLINE]

29:  Sun LQ, Li YX, Guillou L, Mirimanoff RO, Coucke PA. 
 Antitumor and radiosensitizing effects of (E)-2'-deoxy-2'-(fluoromethylene)
cytidine, a novel inhibitor of ribonucleoside diphosphate reductase, on human
colon carcinoma xenografts in nude mice.
Cancer Res. 1997 Sep 15;57(18):4023-8. 
PMID: 9307288 [PubMed - indexed for MEDLINE]

30:  Sjogren AS, Stromberg R, Sjoberg BM. 
 pH dependence of self-splicing by the group IA2 intron in a pre-mRNA derived
from the nrdB gene of bacteriophage T4.
Nucleic Acids Res. 1997 Sep 1;25(17):3543-9. 
PMID: 9254717 [PubMed - indexed for MEDLINE]

31:  Tidona CA, Darai G. 
 The complete DNA sequence of lymphocystis disease virus.
Virology. 1997 Apr 14;230(2):207-16. 
PMID: 9143276 [PubMed - indexed for MEDLINE]

32:  Liu MC, Lin TS, Cory JG, Cory AH, Sartorelli AC. 
 Synthesis and biological activity of 3- and 5-amino derivatives of
pyridine-2-carboxaldehyde thiosemicarbazone.
J Med Chem. 1996 Jun 21;39(13):2586-93. 
PMID: 8691457 [PubMed - indexed for MEDLINE]

33:  Piepmeier JM, Rabidou N, Schold SC Jr, Bitonti AJ, Prakash NJ, Bush TL. 
 In vitro and in vivo inhibition of glioblastoma and neuroblastoma with
MDL101731, a novel ribonucleoside diphosphate reductase inhibitor.
Cancer Res. 1996 Jan 15;56(2):359-61. 
PMID: 8542592 [PubMed - indexed for MEDLINE]

34:  Wright PS, Cross-Doersen D, Th'ng JP, Guo XW, Crissman HA, Bradbury EM,
Montgomery LR, Thompson FY, Loudy DE, Johnston JO, Bitonti AJ. 
 A ribonucleotide reductase inhibitor, MDL 101,731, induces apoptosis and
elevates TRPM-2 mRNA levels in human prostate tumor xenografts.
Exp Cell Res. 1996 Jan 10;222(1):54-60. 
PMID: 8549673 [PubMed - indexed for MEDLINE]

35:  Roy B, Decout JL, Beguin C, Fontecave M, Allard P, Kuprin S, Ehrenberg A. 
 NMR studies of binding of 5-FdUDP and dCDP to ribonucleoside-diphosphate
reductase from Escherichia coli.
Biochim Biophys Acta. 1995 Mar 15;1247(2):284-92. 
PMID: 7696321 [PubMed - indexed for MEDLINE]

36:  Sinhababu AK, Boehlert CC, Gan LS, Yanni SB, Thakker DR. 
 High-performance liquid chromatographic purification, optimization of the
assay, and properties of ribonucleoside diphosphate reductase from rabbit bone
marrow.
Arch Biochem Biophys. 1995 Feb 20;317(1):285-91. 
PMID: 7872796 [PubMed - indexed for MEDLINE]

37:  Liu MC, Lin TS, Sartorelli AC. 
 Chemical and biological properties of cytotoxic alpha-(N)-heterocyclic
carboxaldehyde thiosemicarbazones.
Prog Med Chem. 1995;32:1-35. Review. No abstract available. 
PMID: 8577916 [PubMed - indexed for MEDLINE]

38:  Liuzzi M, Deziel R, Moss N, Beaulieu P, Bonneau AM, Bousquet C, Chafouleas
JG, Garneau M, Jaramillo J, Krogsrud RL, et al. 
 A potent peptidomimetic inhibitor of HSV ribonucleotide reductase with
antiviral activity in vivo.
Nature. 1994 Dec 15;372(6507):695-8. 
PMID: 7990963 [PubMed - indexed for MEDLINE]

39:  Young P, Leeds JM, Slabaugh MB, Mathews CK. 
 Ribonucleotide reductase: evidence for specific association with HeLa cell
mitochondria.
Biochem Biophys Res Commun. 1994 Aug 30;203(1):46-52. 
PMID: 8074691 [PubMed - indexed for MEDLINE]

40:  Hilfinger JM, He P. 
 Bacteriophage T4 ribonucleoside diphosphate reductase: on the defect causing
decreased formation of the beta 93(2) subunit encoded by the nrdB93 mutant gene.
Gene. 1994 May 3;142(1):55-60. 
PMID: 8181757 [PubMed - indexed for MEDLINE]

41:  Allard P, Kuprin S, Ehrenberg A. 
 Conformation of dCDP bound to protein R1 of Escherichia coli ribonucleotide
reductase.
J Magn Reson B. 1994 Mar;103(3):242-6. 
PMID: 8019775 [PubMed - indexed for MEDLINE]

42:  Snyder RD. 
 Effect of 2'-deoxy-2'-(fluoromethylene) cytidine on the ultraviolet and X-ray
sensitivity of HeLa cells.
Oncol Res. 1994;6(4-5):177-82. 
PMID: 7841540 [PubMed - indexed for MEDLINE]

43:  Claverie JM. 
 Detecting frame shifts by amino acid sequence comparison.
J Mol Biol. 1993 Dec 20;234(4):1140-57. 
PMID: 7903399 [PubMed - indexed for MEDLINE]

44:  Sun X, Harder J, Krook M, Jornvall H, Sjoberg BM, Reichard P. 
 A possible glycine radical in anaerobic ribonucleotide reductase from
Escherichia coli: nucleotide sequence of the cloned nrdD gene.
Proc Natl Acad Sci U S A. 1993 Jan 15;90(2):577-81. 
PMID: 8421692 [PubMed - indexed for MEDLINE]

45:  Eliasson R, Pontis E, Fontecave M, Gerez C, Harder J, Jornvall H, Krook M,
Reichard P. 
 Characterization of components of the anaerobic ribonucleotide reductase system
from Escherichia coli.
J Biol Chem. 1992 Dec 15;267(35):25541-7. 
PMID: 1460049 [PubMed - indexed for MEDLINE]

46:  Schallreuter KU, Elgren TE, Nelson LS Jr, MacFarlan S, Yan-Sze I, Hogenkamp
HP. 
 Ribonucleotide diphosphate reductase from human metastatic melanoma.
Melanoma Res. 1992 Dec;2(5-6):393-400. 
PMID: 1338000 [PubMed - indexed for MEDLINE]

47:  Mao SS, Holler TP, Yu GX, Bollinger JM Jr, Booker S, Johnston MI, Stubbe J.

 A model for the role of multiple cysteine residues involved in ribonucleotide
reduction: amazing and still confusing.
Biochemistry. 1992 Oct 13;31(40):9733-43. 
PMID: 1382592 [PubMed - indexed for MEDLINE]

48:  Allard P, Kuprin S, Shen B, Ehrenberg A. 
 Binding of the competitive inhibitor dCDP to ribonucleoside-diphosphate
reductase from Escherichia coli studied by 1H NMR. Different properties of the
large protein subunit and the holoenzyme.
Eur J Biochem. 1992 Sep 15;208(3):635-42. 
PMID: 1396671 [PubMed - indexed for MEDLINE]

49:  Shen B, Allard P, Kuprin S, Ehrenberg A. 
 Studies on ribonucleoside-diphosphate reductase from Escherichia coli. The
product dCDP is a competitive inhibitor and functions as a spectroscopic probe
for the substrate binding site; demonstration by enzyme kinetics and 1H NMR.
Eur J Biochem. 1992 Sep 15;208(3):631-4. 
PMID: 1396670 [PubMed - indexed for MEDLINE]

50:  Gleason FK. 
 Mutation of conserved residues in Escherichia coli thioredoxin: effects on
stability and function.
Protein Sci. 1992 May;1(5):609-16. 
PMID: 1304360 [PubMed - indexed for MEDLINE]

51:  Albert DA, Rozengurt E. 
 Synergistic and coordinate expression of the genes encoding ribonucleotide
reductase subunits in Swiss 3T3 cells: effect of multiple signal-transduction
pathways.
Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1597-601. 
PMID: 1311843 [PubMed - indexed for MEDLINE]

52:  Sitjes J, Ysern P, Barbe J, Llagostera M. 
 Induction of ribonucleoside diphosphate reductase gene transcription by
chemicals in Escherichia coli.
Mutagenesis. 1992 Jan;7(1):47-9. 
PMID: 1635455 [PubMed - indexed for MEDLINE]

53:  Baker CH, Banzon J, Bollinger JM, Stubbe J, Samano V, Robins MJ, Lippert B,
Jarvi E, Resvick R. 
 2'-Deoxy-2'-methylenecytidine and 2'-deoxy-2',2'-difluorocytidine
5'-diphosphates: potent mechanism-based inhibitors of ribonucleotide reductase.
J Med Chem. 1991 Jun;34(6):1879-84. 
PMID: 2061926 [PubMed - indexed for MEDLINE]

54:  Sheid B, Saggar M, Gaetjens E, Lerner LM. 
 Antiproliferative activity of purine nucleoside dialdehydes against leukemia
L1210 in vitro.
Cancer Chemother Pharmacol. 1991;28(5):339-43. 
PMID: 1914076 [PubMed - indexed for MEDLINE]

55:  Takeda E, Kuroda Y, Naito E, Yokota I, Saijo T, Hirose M, Miyao M. 
 Effects of deoxyadenosine on ribonucleotide reductase in adenosine
deaminase-deficient lymphocytes.
J Inherit Metab Dis. 1991;14(1):87-95. 
PMID: 1830628 [PubMed - indexed for MEDLINE]

56:  Heinemann V, Xu YZ, Chubb S, Sen A, Hertel LW, Grindey GB, Plunkett W. 
 Inhibition of ribonucleotide reduction in CCRF-CEM cells by
2',2'-difluorodeoxycytidine.
Mol Pharmacol. 1990 Oct;38(4):567-72. 
PMID: 2233693 [PubMed - indexed for MEDLINE]

57:  Eliasson R, Fontecave M, Jornvall H, Krook M, Pontis E, Reichard P. 
 The anaerobic ribonucleoside triphosphate reductase from Escherichia coli
requires S-adenosylmethionine as a cofactor.
Proc Natl Acad Sci U S A. 1990 May;87(9):3314-8. 
PMID: 2185465 [PubMed - indexed for MEDLINE]

58:  Wang LM, White JC, Capizzi RL. 
 The effect of ara-C-induced inhibition of DNA synthesis on its cellular
pharmacology.
Cancer Chemother Pharmacol. 1990;25(6):418-24. 
PMID: 2311169 [PubMed - indexed for MEDLINE]

59:  Farr RA, Bey P, Sunkara PS, Lippert BJ. 
 Synthesis of acyclonucleoside hydroxamic acids as inhibitors of ribonucleotide
reductase.
J Med Chem. 1989 Aug;32(8):1879-85. 
PMID: 2666666 [PubMed - indexed for MEDLINE]

60:  Rittberg DA, Wright JA. 
 Relationships between sensitivity to hydroxyurea and
4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone (MAIO) and
ribonucleotide reductase RNR2 mRNA levels in strains of Saccharomyces
cerevisiae.
Biochem Cell Biol. 1989 Jul;67(7):352-7. 
PMID: 2675933 [PubMed - indexed for MEDLINE]

61:  Carter GL, Thompson DP, Cory JG. 
 Mechanisms of drug resistance to inhibitors directed at the individual subunits
of ribonucleotide reductase.
Cancer Commun. 1989;1(1):13-20. 
PMID: 2701080 [PubMed - indexed for MEDLINE]

62:  Larsson A, Karlsson M, Sahlin M, Sjoberg BM. 
 Radical formation in the dimeric small subunit of ribonucleotide reductase
requires only one tyrosine 122.
J Biol Chem. 1988 Nov 25;263(33):17780-4. 
PMID: 3053717 [PubMed - indexed for MEDLINE]

63:  Willing A, Follmann H, Auling G. 
 Nucleotide and thioredoxin specificity of the manganese ribonucleotide
reductase from Brevibacterium ammoniagenes.
Eur J Biochem. 1988 Jul 15;175(1):167-73. 
PMID: 3042394 [PubMed - indexed for MEDLINE]

64:  Pulatova MK, Sharygin VL, Filatov DE, Efremova OI, Todorov IN. 
 [The role of ribonucleotide reductase in the regulation of post-radiation DNA
synthesis]
Dokl Akad Nauk SSSR. 1988 May-Jun;300(1):233-6. Russian. No abstract available. 
PMID: 2843339 [PubMed - indexed for MEDLINE]

65:  Prajda N, Natsumeda Y, Ikegami T, Reardon MA, Szondy S, Hashimoto Y, Emrani
J, Weber G. 
 Enzymic programs of rat bone marrow and the impact of acivicin and tiazofurin.
Biochem Pharmacol. 1988 Mar 1;37(5):875-80. 
PMID: 3345200 [PubMed - indexed for MEDLINE]

66:  Orr RM, Davies LC, Stock JA, Taylor GA, Powles RL, Harrap KR. 
 Inhibition of human leukaemic thymidylate kinase and L1210 ribonucleotide
reductase by dinucleotides of adenosine and thymidine and their phosphonate
analogues.
Biochem Pharmacol. 1988 Feb 15;37(4):673-7. 
PMID: 2829920 [PubMed - indexed for MEDLINE]

67:  Hall IH, Grippo AA, Lee KH, Chaney SG, Holbrook DJ. 
 Effect of helenalin and bis(helenalinyl)malonate on nucleic acid and protein
synthesis in human KB carcinoma cells.
Pharm Res. 1987 Dec;4(6):509-14. 
PMID: 2907784 [PubMed - indexed for MEDLINE]

68:  Lin AN, Ashley GW, Stubbe J. 
 Location of the redox-active thiols of ribonucleotide reductase: sequence
similarity between the Escherichia coli and Lactobacillus leichmannii enzymes.
Biochemistry. 1987 Nov 3;26(22):6905-9. 
PMID: 3322391 [PubMed - indexed for MEDLINE]

69:  Salowe SP, Ator MA, Stubbe J. 
 Products of the inactivation of ribonucleoside diphosphate reductase from
Escherichia coli with 2'-azido-2'-deoxyuridine 5'-diphosphate.
Biochemistry. 1987 Jun 16;26(12):3408-16. 
PMID: 3307907 [PubMed - indexed for MEDLINE]

70:  Kren B, Fuchs JA. 
 Characterization of the ftsB gene as an allele of the nrdB gene in Escherichia
coli.
J Bacteriol. 1987 Jan;169(1):14-8. 
PMID: 3025167 [PubMed - indexed for MEDLINE]

71:  Spath A, Tempel K. 
 Diethyldithiocarbamate inhibits scheduled and unscheduled DNA synthesis of rat
thymocytes in vitro and in vivo--dose-effect relationships and mechanisms of
action.
Chem Biol Interact. 1987;64(1-2):151-66. 
PMID: 2826023 [PubMed - indexed for MEDLINE]

72:  Kucera R, Paulus H. 
 Localization of the deoxyribonucleotide biosynthetic enzymes ribonucleotide
reductase and thymidylate synthase in mouse L cells.
Exp Cell Res. 1986 Dec;167(2):417-28. 
PMID: 3533576 [PubMed - indexed for MEDLINE]

73:  Slabaugh MB, Mathews CK. 
 Hydroxyurea-resistant vaccinia virus: overproduction of ribonucleotide
reductase.
J Virol. 1986 Nov;60(2):506-14. 
PMID: 3534300 [PubMed - indexed for MEDLINE]

74:  Turk SR, Shipman C Jr, Drach JC. 
 Structure-activity relationships among alpha-(N)-heterocyclic acyl
thiosemicarbazones and related compounds as inhibitors of herpes simplex virus
type 1-specified ribonucleoside diphosphate reductase.
J Gen Virol. 1986 Aug;67 ( Pt 8):1625-32. 
PMID: 3016157 [PubMed - indexed for MEDLINE]

75:  Turk SR, Shipman C Jr, Drach JC. 
 Selective inhibition of herpes simplex virus ribonucleoside diphosphate
reductase by derivatives of 2-acetylpyridine thiosemicarbazone.
Biochem Pharmacol. 1986 May 1;35(9):1539-45. 
PMID: 3011019 [PubMed - indexed for MEDLINE]

76:  Salowe SP, Stubbe J. 
 Cloning, overproduction, and purification of the B2 subunit of
ribonucleoside-diphosphate reductase.
J Bacteriol. 1986 Feb;165(2):363-6. 
PMID: 3511029 [PubMed - indexed for MEDLINE]

77:  Ator MA, Stubbe J. 
 Mechanism of inactivation of Escherichia coli ribonucleotide reductase by
2'-chloro-2'-deoxyuridine 5'-diphosphate: evidence for generation of a
2'-deoxy-3'-ketonucleotide via a net 1,2 hydrogen shift.
Biochemistry. 1985 Dec 3;24(25):7214-21. 
PMID: 3910098 [PubMed - indexed for MEDLINE]

78:  Cavanaugh PF Jr, Porter CW, Tukalo D, Frankfurt OS, Pavelic ZP, Bergeron
RJ. 
 Characterization of L1210 cell growth inhibition by the bacterial iron
chelators parabactin and compound II.
Cancer Res. 1985 Oct;45(10):4754-9. 
PMID: 4027962 [PubMed - indexed for MEDLINE]

79:  Sjoberg BM, Eklund H, Fuchs JA, Carlson J, Standart NM, Ruderman JV, Bray
SJ, Hunt T. 
 Identification of the stable free radical tyrosine residue in ribonucleotide
reductase. A sequence comparison.
FEBS Lett. 1985 Apr 8;183(1):99-102. 
PMID: 2984052 [PubMed - indexed for MEDLINE]

80:  Chan VL, Guttman S. 
 Codominant and recessive 9-beta-D-arabinofuranosyladenine-resistant mutations
of baby hamster cells.
Mutat Res. 1985 Mar;149(1):141-6. 
PMID: 3974620 [PubMed - indexed for MEDLINE]

81:  Cory JG, Chiba P. 
 Combination chemotherapy directed at the components of nucleoside diphosphate
reductase.
Pharmacol Ther. 1985;29(1):111-27. Review. 
PMID: 3914643 [PubMed - indexed for MEDLINE]

82:  Cory JG, Sato A, Carter GL, Bacon PE, Montgomery JA, Brown NC. 
 The utility of combinations of drugs directed at specific sites of the same
target enzyme--ribonucleotide reductase as the model.
Adv Enzyme Regul. 1985;23:181-92. 
PMID: 3907303 [PubMed - indexed for MEDLINE]

83:  Moore EC, Hurlbert RB. 
 The inhibition of ribonucleoside diphosphate reductase by hydroxyurea,
guanazole and pyrazoloimidazole (IMPY).
Pharmacol Ther. 1985;27(2):167-96. Review. No abstract available. 
PMID: 3898152 [PubMed - indexed for MEDLINE]

84:  Averett DR, Furman PA, Spector T. 
 Ribonucleotide reductase of herpes simplex virus type 2 resembles that of
herpes simplex virus type 1.
J Virol. 1984 Dec;52(3):981-3. 
PMID: 6092726 [PubMed - indexed for MEDLINE]

85:  Slabaugh MB, Johnson TL, Mathews CK. 
 Vaccinia virus induces ribonucleotide reductase in primate cells.
J Virol. 1984 Nov;52(2):507-14. 
PMID: 6387175 [PubMed - indexed for MEDLINE]

86:  Takeda E, Kuroda Y, Watanabe T, Ito M, Naito E, Sekiguchi T, Ichioka T,
Hosoda T, Miyao M. 
 Cytidine 5'-diphosphate reductase and thymidine kinase activities in
phytohemagglutinin-stimulated lymphocytes of normal subjects of various ages and
patients with immunodeficiency.
Pediatr Res. 1984 Aug;18(8):691-6. 
PMID: 6382137 [PubMed - indexed for MEDLINE]

87:  Morita T, Murayama J, Shimizu N, Moriyama Y, Fujimura S. 
 Separation of cytidine diphosphate reductase from rat Yoshida ascites sarcoma.
Biochem Biophys Res Commun. 1984 Jan 13;118(1):212-6. 
PMID: 6365096 [PubMed - indexed for MEDLINE]

88:  Gupta SP, Prabhakar YS, Bindal MC, Handa A. 
 A quantitative analysis of steric and hydrophobic effects in ribonucleoside
diphosphate reductase inhibition by thiosemicarbazones.
Arzneimittelforschung. 1984;34(2):147-50. 
PMID: 6372802 [PubMed - indexed for MEDLINE]

89:  Sato A, Bacon PE, Cory JG. 
 Studies on the differential mechanisms of inhibition of ribonucleotide
reductase by specific inhibitors of the non-heme iron subunit.
Adv Enzyme Regul. 1984;22:231-41. 
PMID: 6089512 [PubMed - indexed for MEDLINE]

90:  Sato A, Fleischer AE, Cory JG. 
 Assay of UDP, GDP, CDP, and ADP reductase activities by column chromatography
on polyethyleneimine cellulose.
Anal Biochem. 1983 Dec;135(2):431-5. 
PMID: 6362485 [PubMed - indexed for MEDLINE]

91:  Kucera R, Brown CL, Paulus H. 
 Cell cycle regulation of ribonucleoside diphosphate reductase activity in
permeable mouse L cells and in extracts.
J Cell Physiol. 1983 Nov;117(2):158-68. 
PMID: 6355126 [PubMed - indexed for MEDLINE]

92:  Neale GA, Mitchell A, Finch LR. 
 Pathways of pyrimidine deoxyribonucleotide biosynthesis in Mycoplasma mycoides
subsp. mycoides.
J Bacteriol. 1983 Apr;154(1):17-22. 
PMID: 6339469 [PubMed - indexed for MEDLINE]

93:  Stubbe J, Ator M, Krenitsky T. 
 Mechanism of ribonucleoside diphosphate reductase from Escherichia coli.
Evidence for 3'-C--H bond cleavage.
J Biol Chem. 1983 Feb 10;258(3):1625-31. 
PMID: 6337142 [PubMed - indexed for MEDLINE]

94:  Muller G. 
 [Immune insufficiency in enzyme defects of purine metabolism]
Z Gesamte Inn Med. 1983 Feb 1;38(3):83-9. German. 
PMID: 6303005 [PubMed - indexed for MEDLINE]

95:  Wright JA. 
 Altered forms of mammalian nucleoside diphosphate reductase from mutant cell
lines.
Pharmacol Ther. 1983;22(1):81-102. Review. No abstract available. 
PMID: 6361799 [PubMed - indexed for MEDLINE]

96:  Fox LM, Mekras JA, Bagwell CB, Greer SB. 
 Capacity of deoxycytidine to selectively antagonize cytotoxicity of
5-halogenated analogs of deoxycytidine without loss of antiherpetic activity.
Antimicrob Agents Chemother. 1982 Sep;22(3):431-41. 
PMID: 6291452 [PubMed - indexed for MEDLINE]

97:  Kucera R, Paulus H. 
 Studies on ribonucleoside-diphosphate reductase in permeable animal cells. II.
Catalytic and regulatory properties of the enzyme in mouse L cells.
Arch Biochem Biophys. 1982 Mar;214(1):114-23. No abstract available. 
PMID: 6177289 [PubMed - indexed for MEDLINE]

98:  Kucera R, Paulus H. 
 Studied on ribonucleoside-diphosphate reductase in permeable animal cells. I.
Reversible permeabilization of mouse L cells with dextran sulfate.
Arch Biochem Biophys. 1982 Mar;214(1):102-13. No abstract available. 
PMID: 6177288 [PubMed - indexed for MEDLINE]

99:  Fabianowska-Majewska K, Greger J. 
 Regulation of deoxynucleoside kinase activities in rat liver mitochondria.
Enzyme. 1982;27(2):124-9. 
PMID: 6121703 [PubMed - indexed for MEDLINE]

100:  Chan VL, Guttman S, Juranka P. 
 Mutator genes of baby hamster kidney cells.
Mol Cell Biol. 1981 Jun;1(6):568-71. 
PMID: 6965110 [PubMed - indexed for MEDLINE]

101:  Akerblom L, Ehrenberg A, Graslund A, Lankinen H, Reichard P, Thelander L. 
 Overproduction of the free radical of ribonucleotide reductase in
hydroxyurea-resistant mouse fibroblast 3T6 cells.
Proc Natl Acad Sci U S A. 1981 Apr;78(4):2159-63. 
PMID: 6264464 [PubMed - indexed for MEDLINE]

102:  Ikenaka K, Fukushima M, Shirasaka T, Fkkjii S. 
 Possible regulation of ribonucleoside diphosphate reductase.
Gann. 1981 Feb;72(1):8-18. 
PMID: 7024035 [PubMed - indexed for MEDLINE]

103:  Dick JE, Wright JA. 
 Ribonucleotide reduction in intact human diploid fibroblasts.
J Cell Physiol. 1980 Oct;105(1):63-72. 
PMID: 7000802 [PubMed - indexed for MEDLINE]

104:  Lin AL, Elford HL. 
 Adenosine deaminase impairment and ribonucleotide reductase activity and levels
in HeLa cells.
J Biol Chem. 1980 Sep 25;255(18):8523-8. 
PMID: 6997299 [PubMed - indexed for MEDLINE]

105:  Feller W, Schimpff-Weiland G, Follmann H. 
 Deoxyribonucleotide biosynthesis in synchronous algae cells.
Eur J Biochem. 1980 Sep;110(1):85-92. 
PMID: 6449366 [PubMed - indexed for MEDLINE]

106:  Allen JR, Reddy GP, Lasser GW, Mathews CK. 
 T4 ribonucleotide reductase. Physical and kinetic linkage to other enzymes of
deoxyribonucleotide biosynthesis.
J Biol Chem. 1980 Aug 25;255(16):7583-8. 
PMID: 6995453 [PubMed - indexed for MEDLINE]

107:  Prem veer Reddy G, Pardee AB. 
 Multienzyme complex for metabolic channeling in mammalian DNA replication.
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3312-16. 
PMID: 6251456 [PubMed - indexed for MEDLINE]

108:  Tsai PK, Hogenkamp HP. 
 The purification and characterization of an adenosylcobalamin-dependent
ribonucleoside diphosphate reductase from Corynebacterium nephridii.
J Biol Chem. 1980 Feb 25;255(4):1273-8. 
PMID: 6986368 [PubMed - indexed for MEDLINE]

109:  de Saint Vincent BR, Dechamps M, Buttin G. 
 The modulation of the thymidine triphosphate pool of Chinese hamster cells by
dCMP deaminase and UDP reductase. Thymidine auxotrophy induced by CTP in dCMP
deaminase-deficient lines.
J Biol Chem. 1980 Jan 10;255(1):162-7. No abstract available. 
PMID: 7350151 [PubMed - indexed for MEDLINE]

110:  Cory JG, Sato A, Lasater L. 
 Specific inhibition of the subunits of ribonucleotide reductase as a new
approach to combination chemotherapy.
Adv Enzyme Regul. 1980;19:139-50. No abstract available. 
PMID: 7039256 [PubMed - indexed for MEDLINE]

111:  Chang CH, Cheng YC. 
 Substrate specificity of human ribonucleotide reductase from Molt-4F cells.
Cancer Res. 1979 Dec;39(12):5081-6. 
PMID: 498135 [PubMed - indexed for MEDLINE]

112:  Meuth M, L'Heureux-Huard N, Trudel M. 
 Characterization of a mutator gene in Chinese hamster ovary cells.
Proc Natl Acad Sci U S A. 1979 Dec;76(12):6505-9. 
PMID: 293738 [PubMed - indexed for MEDLINE]

113:  Luthman M, Eriksson S, Holmgren A, Thelander L. 
 Glutathione-dependent hydrogen donor system for calf thymus
ribonucleoside-diphosphate reductase.
Proc Natl Acad Sci U S A. 1979 May;76(5):2158-62. 
PMID: 377293 [PubMed - indexed for MEDLINE]

114:  Manwaring JD, Fuchs JA. 
 Relationship between deoxyribonucleoside triphosphate pools and
deoxyribonucleic acid synthesis in an nrdA mutant of Escherichia coli.
J Bacteriol. 1979 Apr;138(1):245-8. No abstract available. 
PMID: 374367 [PubMed - indexed for MEDLINE]

115:  Gale GR, Atkins LM, Meischen SJ, Schwartz P. 
 Schedule-dependency assessments of ribonucleoside diphosphate reductase
inhibitors when used in combination with platinum compounds plus
cyclophosphamide in the treatment of advanced L1210 leukemia.
Cancer Treat Rep. 1979 Mar;63(3):449-56. 
PMID: 427825 [PubMed - indexed for MEDLINE]

116:  Tyrsted G, Gamulin V. 
 Cytidine 5'-diphosphate reductase activity in phytohemagglutinin stimulated
human lymphocytes.
Nucleic Acids Res. 1979 Jan;6(1):305-19. 
PMID: 424294 [PubMed - indexed for MEDLINE]

117:  Lewis WH, Wright JA. 
 Ribonucleotide reductase from wild type and hydroxyurea-resistant chinese
hamster ovary cells.
J Cell Physiol. 1978 Oct;97(1):87-97. 
PMID: 568630 [PubMed - indexed for MEDLINE]

118:  Wagner W, Follmann H, Schmidt A. 
 Multiple functions of thioredoxins.
Z Naturforsch [C]. 1978 Jul-Aug;33(7-8):517-20. 
PMID: 212888 [PubMed - indexed for MEDLINE]

119:  Langelier Y, Dechamps M, Buttin G. 
 Aanlysis of dCMP deaminase and CDP reductase levels in hamster cells infected
by herpes simplex virus.
J Virol. 1978 Jun;26(3):547-53. 
PMID: 209209 [PubMed - indexed for MEDLINE]

120:  Kummer D, Kraml F, Heitland W, Jacob E. 
 [Control mechanisms of the ribonucleotide reduction in mammalian tissue
(author's transl)]
Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. 1978 Jan 26;91(1):23-34. German.

PMID: 146339 [PubMed - indexed for MEDLINE]

121:  Petrovich IuA, Terekhina NA. 
 [Enzymology of cells infected with herpes simplex virus]
Vopr Virusol. 1977 Nov-Dec;(6):643-9. Russian. No abstract available. 
PMID: 203110 [PubMed - indexed for MEDLINE]

122:  Cohen JC, Henry BE, Randall CC, O'Callaghan DJ. 
 Ribonucleotide reductase activity in hydroxyurea-resistant herpesvirus
replication.
Proc Soc Exp Biol Med. 1977 Jul;155(3):395-9. No abstract available. 
PMID: 195286 [PubMed - indexed for MEDLINE]

123:  Agrawal KC, Schenkman JB, Denk H, Mooney PD, Moore EC, Wodinsky I,
Sartorelli AC. 
 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone, a second-generation
antineoplastic agent of the alpha-(N)-heterocyclic carboxaldehyde
thiosemicarbazone series.
Cancer Res. 1977 Jun;37(6):1692-6. 
PMID: 870183 [PubMed - indexed for MEDLINE]

124:  Filpula D, Fuchs JA. 
 Regulation of ribonucleoside diphosphate reductase synthesis in Escherichia
coli: increased enzyme synthesis as a result of inhibition of deoxyribonucleic
acid synthesis.
J Bacteriol. 1977 Apr;130(1):107-13. 
PMID: 67110 [PubMed - indexed for MEDLINE]

125:  Antholine W, Knight J, Whelan H, Petering DH. 
 Studies of the reaction of 2-formylpyridine thiosemicarbazone and its iron and
copper complexes with biological systems.
Mol Pharmacol. 1977 Jan;13(1):89-98. No abstract available. 
PMID: 834188 [PubMed - indexed for MEDLINE]

126:  Beck CF, Neuhard J, Thomassen E. 
 Thymidine-requiring mutants of Salmonella typhimurium that are defective in
deoxyuridine 5'-phosphate synthesis.
J Bacteriol. 1977 Jan;129(1):305-16. 
PMID: 318643 [PubMed - indexed for MEDLINE]

127:  Wovcha MG, Chiu CS, Tomich PK, Greenberg GR. 
 Replicative bacteriophage DNA synthesis in plasmolyzed T4-infected cells:
evidence for two independent pathways to DNA.
J Virol. 1976 Oct;20(1):142-56. 
PMID: 789911 [PubMed - indexed for MEDLINE]

128:  Holmgren A. 
 Hydrogen donor system for Escherichia coli ribonucleoside-diphosphate reductase
dependent upon glutathione.
Proc Natl Acad Sci U S A. 1976 Jul;73(7):2275-9. 
PMID: 7783 [PubMed - indexed for MEDLINE]

129:  von Dobeln U, Reichard P. 
 Binding of substrates to Escherichia coli ribonucleotide reductase.
J Biol Chem. 1976 Jun 25;251(12):3616-22. 
PMID: 776972 [PubMed - indexed for MEDLINE]

130:  Peterson DM, Moore EC. 
 Independent fluctuations of cytidine and adenosine diphosphate reductase
activities in cultured Chinese hamster fibroblasts.
Biochim Biophys Acta. 1976 Apr 15;432(1):80-91. 
PMID: 1260052 [PubMed - indexed for MEDLINE]

131:  Heinonen J, Joronen I, Tuokko H. 
 Adaptation of the cells of Escherichia coli to the presence of hydroxyurea
increases the level of inorganic pyrophosphatase acttivity.
Chem Biol Interact. 1976 Jan;12(1):91-8. 
PMID: 764988 [PubMed - indexed for MEDLINE]

132:  Fuchs JA, Warner HR. 
 Isolation of an Escherichia coli mutant deficient in glutathione synthesis.
J Bacteriol. 1975 Oct;124(1):140-8. 
PMID: 1100598 [PubMed - indexed for MEDLINE]

133:  Berglund O. 
 Ribonucleoside diphosphate reductase induced by bacteriophage T4. III.
Isolation and characterization of proteins B1 and B2.
J Biol Chem. 1975 Sep 25;250(18):7450-5. 
PMID: 809436 [PubMed - indexed for MEDLINE]

134:  Eriksson S. 
 Ribonucleotide reductase from Escherichia coli: demonstration of a highly
active form of the enzyme.
Eur J Biochem. 1975 Aug 1;56(1):289-94. 
PMID: 240707 [PubMed - indexed for MEDLINE]

135:  Mooney PD, Booth BA, Moore EC, Agrawal KC, Sartorelli AC. 
 Potential antitumor agents. 10. Synthesis and biochemical properties of
5-N-alkylamino-,N,N-dialkylamino-, and N-alkylacetamido-1-formylisoquinoline
thiosemicarbazones.
J Med Chem. 1974 Nov;17(11):1145-50. No abstract available. 
PMID: 4370274 [PubMed - indexed for MEDLINE]

136:  Warner HR. 
 Properties of ribonucleoside diphosphate reductase in nucleotide-permeable
cells.
J Bacteriol. 1973 Jul;115(1):18-22. No abstract available. 
PMID: 4146181 [PubMed - indexed for MEDLINE]

137:  Berglund O. 
 Ribonucleoside diphosphate reductase induced by bacteriophage Tr. I.
Purification and characterization.
J Biol Chem. 1972 Nov 25;247(22):7270-5. No abstract available. 
PMID: 4344645 [PubMed - indexed for MEDLINE]

138:  David S, Eustache J. 
 [Stereospecificity of ribonucleoside diphosphate reductase: preparation of
deuterated pyrimidine deoxyribonucleosides]
Carbohydr Res. 1971 Dec;20(2):319-27. French. No abstract available. 
PMID: 4948928 [PubMed - indexed for MEDLINE]

139:  David S, Rouzeau C. 
 Ribonucleoside diphosphate reductase from Escherichia coli: a new approach to
the problem of stereospecificity.
Biochem Biophys Res Commun. 1971 Apr 2;43(1):46-9. No abstract available. 
PMID: 4931566 [PubMed - indexed for MEDLINE]

140:  Moore EC, Zedeck MS, Agrawal KC, Sartorelli AC. 
 Inhibition of ribonucleoside diphosphate reductase by 1-formylisoquinoline
thiosemicarbazone and related compounds.
Biochemistry. 1970 Nov 10;9(23):4492-8. No abstract available. 
PMID: 5529812 [PubMed - indexed for MEDLINE]

141:  Brown NC, Reichard P. 
 Role of effector binding in allosteric control of ribonucleoside diphosphate
reductase.
J Mol Biol. 1969 Nov 28;46(1):39-55. No abstract available. 
PMID: 4902212 [PubMed - indexed for MEDLINE]

142:  Brown NC, Reichard P. 
 Ribonucleoside diphosphate reductase. Formation of active and inactive
complexes of proteins B1 and B2.
J Mol Biol. 1969 Nov 28;46(1):25-38. No abstract available. 
PMID: 4902211 [PubMed - indexed for MEDLINE]

143:  Krakoff IH, Brown NC, Reichard P. 
 Inhibition of ribonucleoside diphosphate reductase by hydroxyurea.
Cancer Res. 1968 Aug;28(8):1559-65. No abstract available. 
PMID: 4876978 [PubMed - indexed for MEDLINE]

144:  Brown NC, Larsson A, Reichard P. 
 On the subunit structure of ribonucleoside diphosphate reductase.
J Biol Chem. 1967 Sep 25;242(18):4272-3. No abstract available. 
PMID: 4294049 [PubMed - indexed for MEDLINE]

145:  Larsson A, Reichard P. 
 Enzymatic synthesis of deoxyribonucleotides. IX. Allosteric effects in the
reduction of pyrimidine ribonucleotides by the ribonucleoside diphosphate
reductase system of Escherichia coli.
J Biol Chem. 1966 Jun 10;241(11):2533-9. No abstract available. 
PMID: 5330119 [PubMed - indexed for MEDLINE]

146:  Larsson A, Reichard P. 
 Allosteric effects and substrate specificity of the ribonucleoside diphosphate
reductase system from Escherichia coli B.
Biochim Biophys Acta. 1966 Feb 14;113(2):407-8. No abstract available. 
PMID: 5328937 [PubMed - indexed for MEDLINE]