1: Proc Natl Acad Sci U S A. 1984 Jul;81(14):4294-7.

Primary structure of the Escherichia coli ribonucleoside diphosphate reductase
operon.

Carlson J, Fuchs JA, Messing J.

The nucleotide sequence of the Escherichia coli K-12 DNA comprising the operon
for the structural genes of the subunits of ribonucleotide diphosphate reductase
has been determined. The DNA sequenced maps at 48.5 minutes on the E. coli
chromosome and includes a total length of 8557 nucleotides. An open reading
frame between nucleotides 3506 and 5834, encoding a 776-amino acid polypeptide
chain with a molecular weight of 87,532, has been identified as the nrdA gene.
An open reading frame between nucleotides 6012 and 7139, encoding a 375-amino
acid polypeptide with a molecular weight of 43,466, has been identified as the
nrdB gene. The sequences reveal not only the primary structures for both
subunits, but also some interesting aspects of potential regulatory sites.

PMID: 6087316 [PubMed - indexed for MEDLINE]

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