# STOCKHOLM 1.0 #=GF ID 4_1_CTD #=GF AC PF05902.6 #=GF DE 4.1 protein C-terminal domain (CTD) #=GF AU Moxon SJ #=GF SE Reference 1 #=GF GA 25.00 25.00; #=GF TC 26.60 26.60; #=GF NC 19.30 18.30; #=GF BM hmmbuild HMM.ann SEED.ann #=GF SM hmmsearch -Z 9421015 -E 1000 HMM pfamseq #=GF TP Domain #=GF RN [1] #=GF RM 11432737 #=GF RT Properties of the C-terminal domain of 4.1 proteins. #=GF RA Scott C, Phillips GW, Baines AJ; #=GF RL Eur J Biochem 2001;268:3709-3717. #=GF DR INTERPRO; IPR008379; #=GF CC At the C-terminus of all known 4.1 proteins is a sequence domain #=GF CC unique to these proteins, known as the C-terminal domain (CTD). #=GF CC Mammalian CTDs are associated with a growing number of #=GF CC protein-protein interactions, although such activities have yet #=GF CC to be associated with invertebrate CTDs. Mammalian CTDs are #=GF CC generally defined by sequence alignment as encoded by exons #=GF CC 18-21. Comparison of known vertebrate 4.1 proteins with #=GF CC invertebrate 4.1 proteins indicates that mammalian 4.1 exon 19 #=GF CC represents a vertebrate adaptation that extends the sequence of #=GF CC the CTD with a Ser/Thr-rich sequence. The CTD was first #=GF CC described as a 22/24-kDa domain by chymotryptic digestion of #=GF CC erythrocyte 4.1 (4.1R). CTD is thought to represent an #=GF CC independent folding structure which has gained function since #=GF CC the divergence of vertebrates from invertebrates [1]. #=GF SQ 126 #=GS Q3U0G7_MOUSE/3-117 AC Q3U0G7.1 #=GS A2A835_MOUSE/257-371 AC A2A835.1 #=GS A2A841_MOUSE/752-866 AC A2A841.1 #=GS 41_MOUSE/741-855 AC P48193.2 #=GS A2A844_MOUSE/79-193 AC A2A844.1 #=GS A2A834_MOUSE/132-246 AC A2A834.1 #=GS A2A838_MOUSE/550-664 AC A2A838.1 #=GS A2A840_MOUSE/687-801 AC A2A840.1 #=GS B6ZHC2_MOUSE/200-314 AC B6ZHC2.1 #=GS A2A842_MOUSE/652-766 AC A2A842.1 #=GS Q3V048_MOUSE/55-169 AC Q3V048.1 #=GS B6ZHC8_MOUSE/706-820 AC B6ZHC8.1 #=GS B6ZHC3_MOUSE/67-181 AC B6ZHC3.1 #=GS Q6DCU8_XENLA/683-797 AC Q6DCU8.1 #=GS 41_XENLA/686-800 AC P11434.1 #=GS Q6PA55_XENLA/652-737 AC Q6PA55.1 #=GS A0JLY5_XENTR/770-855 AC A0JLY5.1 #=GS Q4VAG6_XENTR/769-854 AC Q4VAG6.1 #=GS C3ZA69_BRAFL/559-647 AC C3ZA69.1 #=GS Q4RHU6_TETNG/420-510 AC Q4RHU6.1 #=GS Q9JMB3_RAT/985-1098 AC Q9JMB3.1 #=GS Q9JMB2_RAT/843-956 AC Q9JMB2.1 #=GS A3E0T0_RAT/750-863 AC A3E0T0.1 #=GS E41L3_MOUSE/809-922 AC Q9WV92.1 #=GS B6ZHD1_MOUSE/809-922 AC B6ZHD1.1 #=GS A7YY80_MOUSE/756-869 AC A7YY80.1 #=GS A7MCX4_MOUSE/90-203 AC A7MCX4.1 #=GS B7Z338_HUMAN/272-385 AC B7Z338.1 #=GS B7Z8M8_HUMAN/359-472 AC B7Z8M8.1 #=GS Q5R604_PONAB/689-802 AC Q5R604.1 #=GS Q5R6C1_PONAB/967-1080 AC Q5R6C1.1 #=GS E41L3_HUMAN/967-1080 AC Q9Y2J2.2 #=GS B7Z2D7_HUMAN/239-352 AC B7Z2D7.1 #=GS Q5RBV8_PONAB/549-662 AC Q5RBV8.1 #=GS B3KT50_HUMAN/202-315 AC B3KT50.1 #=GS A8K968_HUMAN/636-749 AC A8K968.1 #=GS B3KY28_HUMAN/636-749 AC B3KY28.1 #=GS Q8BT38_MOUSE/218-303 AC Q8BT38.1 #=GS B7Z2G3_HUMAN/264-377 AC B7Z2G3.1 #=GS B7Z4I5_HUMAN/798-883 AC B7Z4I5.1 #=GS Q6NSM6_DANRE/718-831 AC Q6NSM6.1 #=GS B0BLX3_DANRE/738-823 AC B0BLX3.1 #=GS Q68EI5_DANRE/741-826 AC Q68EI5.1 #=GS Q4RWU7_TETNG/1011-1124 AC Q4RWU7.1 #=GS Q4RCJ7_TETNG/4-62 AC Q4RCJ7.1 #=GS B6ZHC4_MOUSE/1-83 AC B6ZHC4.1 #=GS Q4SJY1_TETNG/1090-1197 AC Q4SJY1.1 #=GS A8KBD9_XENTR/717-811 AC A8KBD9.1 #=GS Q29RW3_HUMAN/2-68 AC Q29RW3.1 #=GS Q4VXM5_HUMAN/2-106 AC Q4VXM5.1 #=GS E41L1_HUMAN/764-869 AC Q9H4G0.2 #=GS E41L1_RAT/762-867 AC Q9WTP0.1 #=GS B3KUB6_HUMAN/655-760 AC B3KUB6.1 #=GS A2AUK6_MOUSE/514-619 AC A2AUK6.1 #=GS B6ZHC9_MOUSE/770-867 AC B6ZHC9.1 #=GS A2AUK5_MOUSE/770-867 AC A2AUK5.1 #=GS A2AUK8_MOUSE/758-855 AC A2AUK8.1 #=GS E41L1_MOUSE/770-867 AC Q9Z2H5.2 #=GS Q4SR26_TETNG/656-765 AC Q4SR26.1 #=GS A2AUK7_MOUSE/610-718 AC A2AUK7.1 #=GS Q59FD8_HUMAN/562-670 AC Q59FD8.1 #=GS B4DHI8_HUMAN/559-667 AC B4DHI8.1 #=GS Q6ZSX4_HUMAN/138-195 AC Q6ZSX4.1 #=GS Q4T9L4_TETNG/567-679 AC Q4T9L4.1 #=GS A2A839_MOUSE/578-636 AC A2A839.1 #=GS B1ALH9_HUMAN/527-585 AC B1ALH9.1 #=GS B0V3D7_DANRE/1-29 AC B0V3D7.1 #=GS A7SJJ2_NEMVE/563-681 AC A7SJJ2.1 #=GS C3ZA69_BRAFL/643-697 AC C3ZA69.1 #=GS A8P5U7_BRUMA/2152-2268 AC A8P5U7.1 #=GS A8X7B8_CAEBR/6358-6473 AC A8X7B8.2 #=GS Q9TVI9_CAEEL/4536-4648 AC Q9TVI9.2 #=GS Q7YSV5_CAEEL/4429-4541 AC Q7YSV5.1 #=GS O18673_CAEEL/4418-4530 AC O18673.3 #=GS Q9XV97_CAEEL/519-634 AC Q9XV97.2 #=GS B0WF91_CULQU/1611-1700 AC B0WF91.1 #=GS Q170K4_AEDAE/1560-1659 AC Q170K4.1 #=GS Q7PVA6_ANOGA/1551-1648 AC Q7PVA6.4 #=GS B4JVC4_DROGR/1623-1732 AC B4JVC4.1 #=GS B4MK66_DROWI/1634-1742 AC B4MK66.1 #=GS Q28Z97_DROPS/1637-1751 AC Q28Z97.2 #=GS B4GI25_DROPE/1631-1745 AC B4GI25.1 #=GS B3NJJ1_DROER/1631-1743 AC B3NJJ1.1 #=GS B4HPC7_DROSE/1630-1742 AC B4HPC7.1 #=GS 41_DROME/1586-1698 AC Q9V8R9.1 #=GS B4PBP4_DROYA/1631-1746 AC B4PBP4.1 #=GS B3MBJ9_DROAN/1637-1749 AC B3MBJ9.1 #=GS B4MCP4_DROVI/1631-1741 AC B4MCP4.1 #=GS B4KU65_DROMO/1619-1726 AC B4KU65.1 #=GS B7Q520_IXOSC/728-862 AC B7Q520.1 #=GS B2DBN1_9NEOP/62-182 AC B2DBN1.1 #=GS A5WUS4_DANRE/20-133 AC A5WUS4.1 #=GS C0PUS5_SALSA/448-561 AC C0PUS5.1 #=GS B0V3D8_DANRE/187-244 AC B0V3D8.1 #=GS Q4SC32_TETNG/853-990 AC Q4SC32.1 #=GS Q9UG62_HUMAN/53-166 AC Q9UG62.1 #=GS Q6R5J7_HUMAN/264-377 AC Q6R5J7.1 #=GS Q5RC68_PONAB/620-733 AC Q5RC68.1 #=GS O60642_HUMAN/30-143 AC O60642.1 #=GS E41L2_HUMAN/886-999 AC O43491.1 #=GS B4DJ76_HUMAN/175-288 AC B4DJ76.1 #=GS Q68DV2_HUMAN/628-741 AC Q68DV2.1 #=GS Q8BSR4_MOUSE/1-108 AC Q8BSR4.1 #=GS Q811B2_MOUSE/572-683 AC Q811B2.1 #=GS B6ZHC6_MOUSE/572-683 AC B6ZHC6.1 #=GS Q9GMU0_MACFA/8-120 AC Q9GMU0.1 #=GS Q80UE4_MOUSE/676-788 AC Q80UE4.1 #=GS B6ZHC5_MOUSE/676-788 AC B6ZHC5.1 #=GS B6ZHC7_MOUSE/664-775 AC B6ZHC7.1 #=GS Q7TPN6_MOUSE/178-291 AC Q7TPN6.1 #=GS E41L2_MOUSE/869-982 AC O70318.1 #=GS Q80UE5_MOUSE/799-912 AC Q80UE5.1 #=GS Q80UE3_MOUSE/869-982 AC Q80UE3.1 #=GS Q3UNQ6_MOUSE/869-982 AC Q3UNQ6.1 #=GS B6ZHD0_MOUSE/869-982 AC B6ZHD0.1 #=GS 41_BOVIN/500-614 AC Q9N179.1 #=GS 41_CANFA/693-807 AC Q6Q7P4.1 #=GS B7Z5L2_HUMAN/81-195 AC B7Z5L2.1 #=GS Q1WWM3_HUMAN/625-739 AC Q1WWM3.1 #=GS Q59F12_HUMAN/710-824 AC Q59F12.1 #=GS 41_HUMAN/747-861 AC P11171.4 #=GS Q4VB86_HUMAN/505-619 AC Q4VB86.2 #=GS A8MU61_HUMAN/435-549 AC A8MU61.1 #=GS Q4VB87_HUMAN/498-612 AC Q4VB87.1 #=GS B7Z627_HUMAN/42-152 AC B7Z627.1 #=GS Q29RX4_HUMAN/567-675 AC Q29RX4.1 Q3U0G7_MOUSE/3-117 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A835_MOUSE/257-371 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A841_MOUSE/752-866 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... 41_MOUSE/741-855 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A844_MOUSE/79-193 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A834_MOUSE/132-246 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A838_MOUSE/550-664 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A840_MOUSE/687-801 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B6ZHC2_MOUSE/200-314 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A2A842_MOUSE/652-766 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q3V048_MOUSE/55-169 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B6ZHC8_MOUSE/706-820 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIAITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B6ZHC3_MOUSE/67-181 ...................................................k-SEISTKDVPIVHTETKTITYE.AAQT..eDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q6DCU8_XENLA/683-797 ..................................................kg--EIPTKEVPLVHTETKTITYE.AARS..dDVN.....T.....DQE.PGILLTAHT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDGD.LDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... 41_XENLA/686-800 ..................................................kg--EIPTKEVPLVHTETKTITYE.AARS..dDVN.....T.....DQE.PGILLTAHT.ITSETTS....ST.TTTQIT....K........................TVKGGISETL..I..EKRIVITGDGD.LDHDQVLVQAIKEAKEQHPDMSVTKGVVHQETEI...... Q6PA55_XENLA/652-737 ..................................................kp--DISTKDVPVVHTETKTITYE.SSET...GAR.....T.....DTD.PGMLMSAQT.ITSETFG....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQ-----------------------------e..... A0JLY5_XENTR/770-855 ..................................................kp--DISTKDVPVVHTETKTITYE.SSEL...GSR.....T.....DTD.PGMLMSAQT.ITSETFG....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQ-----------------------------e..... Q4VAG6_XENTR/769-854 ..................................................kp--DISTKDVPVVHTETKTITYE.SSEL...GSR.....T.....DTD.PGMLMSAQT.ITSETFG....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQ-----------------------------e..... C3ZA69_BRAFL/559-647 ...............................................aqpef-----TSSVPIVKTESKTITYE.Q-NE...DGE.....P.....DQD.PGVLVSAQT.VTSETIS....TT.TTTHIT....K........................TVKGGVAETR..I..EKRIVITGDTD.IDHDQYM---------------------------kkd... Q4RHU6_TETNG/420-510 ...............................................ttttt---TTTTDVPV--VPTQTIIYE.SSKE..pDEG.....T.....EKD.SMTVSSSTS.ITSETTSgttvTT.TTTHIS....K........................VVKSGSTETR..M..EKRIVITADSD.ADQDK-----------------------------v..... Q9JMB3_RAT/985-1098 ..................................................kl--ETSTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q9JMB2_RAT/843-956 ..................................................kl--ETSTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... A3E0T0_RAT/750-863 ..................................................kl--ETSTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... E41L3_MOUSE/809-922 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B6ZHD1_MOUSE/809-922 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... A7YY80_MOUSE/756-869 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... A7MCX4_MOUSE/90-203 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B7Z338_HUMAN/272-385 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B7Z8M8_HUMAN/359-472 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q5R604_PONAB/689-802 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q5R6C1_PONAB/967-1080 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... E41L3_HUMAN/967-1080 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B7Z2D7_HUMAN/239-352 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q5RBV8_PONAB/549-662 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B3KT50_HUMAN/202-315 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... A8K968_HUMAN/636-749 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B3KY28_HUMAN/636-749 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q8BT38_MOUSE/218-303 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....A.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQ-----------------------------e..... B7Z2G3_HUMAN/264-377 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVEVHKETEI...... B7Z4I5_HUMAN/798-883 ...................................................k-LEISTKEVPVVHTETKTITYE.SSQV...DPG.....T.....DLE.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQ-----------------------------e..... Q6NSM6_DANRE/718-831 ..................................................qc--EEAVKDVPVVHTETKTITYE.SSEA...DAN.....G.....DSN.PGVFMSAQT.ITSEKNS....TT.TTTHIT....K........................TVKDGISETR..I..EKRIVISGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... B0BLX3_DANRE/738-823 .................................................gdt---HETHDTPVIQTEIKTITYE.ALQA...ETD.....G.....DAD.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVISGDAD.IDHDE-----------------------------d..... Q68EI5_DANRE/741-826 .................................................hdt---HETHDTPVIQTEIKTITYE.ALQA...ETD.....G.....DAD.PGVLMSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVISGDAD.IDHDE-----------------------------d..... Q4RWU7_TETNG/1011-1124 ...................................................a-TDAGTKEMPVIHTETKTITYE.SAEV...DTN.....G.....DFD.PGVLLSAQT.ITSETTS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVISGDAD.IDHDQALAQAIKEAKEQHPDMSVTKVVVHKETEI...... Q4RCJ7_TETNG/4-62 ...................................................a-TDAGTKEMPVIHTETKTITYE.SAEV...DTN.....G.....DFD.PGVLLSAQT.ITSETTS....TT.TTTHIT....K........................----------..-..-----------.----------------------------------v..... B6ZHC4_MOUSE/1-83 .........................................vdggtpmvkdf----------------------.----...---.....-.....---.---------.MTTPPCI....TT.ETISTT....M........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... Q4SJY1_TETNG/1090-1197 ...................................................d-QNISSEGHISDLIADAGFCSQ.VHVG..sLGR.....E.....SAG.SPILVAEN-.------V....TS.ATTHVT....K........................TVKGGYSETR..I..EKRIIITGDDD.VDQEQALAIAIQEAKQQHPDMQVTKAVVVRETES...... A8KBD9_XENTR/717-811 ................................aqgshtdgarthhalptaii----------------------.----...---.....-.....---.------PHA.ATAETLS....SS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQEQALALAIKEAKLQHPDMMVTKAVVYCETE-p..... Q29RW3_HUMAN/2-68 ..................................................pr----------------------.----...---.....-.....---.---------.-------....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... Q4VXM5_HUMAN/2-106 .........................................vgrefiattps------------------ITTE.--TI...STT.....M.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... E41L1_HUMAN/764-869 ...............................kgaaamipgpqtvateirsls----------------------.----...---.....P.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... E41L1_RAT/762-867 ...............................kgaaamipgpqtvateirsls----------------------.----...---.....P.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... B3KUB6_HUMAN/655-760 ...............................kgaaamipgpqtvateirsls----------------------.----...---.....P.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... A2AUK6_MOUSE/514-619 ...............................kgaaamipgpqtvateirsls----------------------.----...---.....P.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... B6ZHC9_MOUSE/770-867 ......................................gpqtvateirslsp----------------------.----...---.....-.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... A2AUK5_MOUSE/770-867 ......................................gpqtvateirslsp----------------------.----...---.....-.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... A2AUK8_MOUSE/758-855 ......................................gpqtvateirslsp----------------------.----...---.....-.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... E41L1_MOUSE/770-867 ......................................gpqtvateirslsp----------------------.----...---.....-.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... Q4SR26_TETNG/656-765 ..................................................gl--CIRCVLLCVYVTSPLTIGLQ.V---...-KT.....N.....IQE.KDPVTSLLT.ITAENVT....SA.TTTQVT....K........................TVKGGYSETR..I..EKRIIITGDDD.VDQHQALAMAIQEAKQQHPDMLVTKAVVIRESES...... A2AUK7_MOUSE/610-718 .............................ksgkgaaamipgpqtvateirsl----------------------.----...--S.....P.....IIG.KDVLTSTYG.ATAETLS....TS.TTTHVT....K........................TVKGGFSETR..I..EKRIIITGDED.VDQDQALALAIKEAKLQHPDMLVTKAVVYRETD-p..... Q59FD8_HUMAN/562-670 ................................................mdqs----LMKDFPGAAGEISAYGPG.LVSI...---.....-.....---.--AVVQDGD.GRREVRS....PT.KAPHLQliegK........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B4DHI8_HUMAN/559-667 ................................................mdqs----LMKDFPGAAGEISAYGPG.LVSI...---.....-.....---.--AVVQDGD.GRREVRS....PT.KAPHLQliegK........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q6ZSX4_HUMAN/138-195 ...................................................p----------------------.----...---.....-.....---.---------.-------....--.------....Q........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q4T9L4_TETNG/567-679 .........................tvstvsageqlqpsspvlktqtitisd----------------------.----...--V.....T.....EAL.RGVVVYRDA.PLGHSET....KT.GSYESA....Q........................TVKGGISETR..I..EKRIVITGDTE.IDHDKALAQAIKEAKEQHPDMSVTRVVVHQETEI...... A2A839_MOUSE/578-636 ..................................................aa----------------------.----...---.....-.....---.---------.-------....--.------....Q........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B1ALH9_HUMAN/527-585 ..................................................aa----------------------.----...---.....-.....---.---------.-------....--.------....Q........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B0V3D7_DANRE/1-29 ....................................................----------------------.----...---.....-.....---.---------.-------....--.------....-........................----------..-..-----------.-----ALAQAIKEAKEQHPDMSVTRVVVHKETEL...... A7SJJ2_NEMVE/563-681 .......................................vtsetvrhtampt------------EIITKTITIE.GDGG...PLT.....A.....AEL.KEIMAQQATaTTSEVIT....TSyTTTTRT....Q........................TVERTLDETInlVdeDGNVIATGDPD.T--DAAIAEAIRQAREADPNVKVTEVVITRNDE-s..... C3ZA69_BRAFL/643-697 .................................................ymk----------------------.----...---.....-.....---.---------.-------....--.------....-........................--KDGTLETH..M..ERTTVLTGDSN.--QDEALADLIKEAADQNPDMTVTKVVVHKEE--ge.... A8P5U7_BRUMA/2152-2268 ..................................................ne--NMTSLQAPIVETVDNKLTCEpANDIdkiNGN.....D.....YSDiPGELVSSHT.VTQGNRT....IE.TIT--Y....K........................TEKNGTVETH..V..EHRVTIHSCDD.IDHDAELTQAILEATNMNPDMTVEKIEVKHESQ-c..... A8X7B8_CAEBR/6358-6473 .............................................deaggds--------TGIVETQTRTMTYE.AQGG...ENAappgwA.....EQG.LGEYVSSKS.VTQGNRT....IE.---TIT...yK........................TEKDGVVETH..V..EHRVTIHSDGD.IDHDAELSQAIMEATQMNPDMVVEKIEVRQETT-q..... Q9TVI9_CAEEL/4536-4648 ..............................................ggengg----------IVETQTRTMTYE.AQGG...ENS.....AppgwaEEG.LGEYVSSKS.VTQGNR-....--.TIETIT...yK........................TEKDGIVETH..V..EHRVTIHSDGD.IDHDAELSQAILEATQMNPDMVVEKIEVRQETT-q..... Q7YSV5_CAEEL/4429-4541 ..............................................ggengg----------IVETQTRTMTYE.AQGG...ENS.....AppgwaEEG.LGEYVSSKS.VTQGNR-....--.TIETIT...yK........................TEKDGIVETH..V..EHRVTIHSDGD.IDHDAELSQAILEATQMNPDMVVEKIEVRQETT-q..... O18673_CAEEL/4418-4530 ..............................................ggengg----------IVETQTRTMTYE.AQGG...ENS.....AppgwaEEG.LGEYVSSKS.VTQGNR-....--.TIETIT...yK........................TEKDGIVETH..V..EHRVTIHSDGD.IDHDAELSQAILEATQMNPDMVVEKIEVRQETT-q..... Q9XV97_CAEEL/519-634 ...........................................qngggengg----------IVETQTRTMTYE.AQGG...ENS.....AppgwaEEG.LGEYVSSKS.VTQGNR-....--.TIETIT...yK........................TEKDGIVETH..V..EHRVTIHSDGD.IDHDAELSQAILEATQMNPDMVVEKIEVRQETT-q..... B0WF91_CULQU/1611-1700 .................................ptgpnvehhrvllddsqsg----------------------.----...---.....-.....VTA.EGEIVSSQT.VSSKTRT....--.----VEtityK........................TERDGVVETR..V..EQKITIQSDGDpIDHDKALAEAIQASRR------------------frtdpe Q170K4_AEDAE/1560-1659 ..................................sgpnvehhrvllddsqeg----------------------.----...---.....-.....VTA.EGEIVSSQT.VSSKTRT....V-.-----EtityK........................TERDGVVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... Q7PVA6_ANOGA/1551-1648 ......................................nvehrrvvlddlae----------------------.----...--G.....G.....TTT.HGEIVSSQT.VSSKTRT....VE.TIT--Y....K........................TERDGVVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4JVC4_DROGR/1623-1732 ............................kqkspltastsgphvestrvvlge----------------------.----...DTP.....G.....FSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4MK66_DROWI/1634-1742 .............................tsstgathptgphvestrvvlge----------------------.----...DAP.....G.....YSG.QGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... Q28Z97_DROPS/1637-1751 .........................dnqksplysssattttgphvestrvvl----------------------.--GE...DTP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4GI25_DROPE/1631-1745 .........................dnqksplysssattttgphvestrvvl----------------------.--GE...DTP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B3NJJ1_DROER/1631-1743 ...........................dnqksplyttsattgphvestrvvl----------------------.--GE...DTP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4HPC7_DROSE/1630-1742 ..........................dnqksplfttsattgphvestrvvlg----------------------.---E...DTP.....G.....FSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... 41_DROME/1586-1698 ..........................dnqksplfttsattgphvestrvvlg----------------------.---E...DTP.....G.....FSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4PBP4_DROYA/1631-1746 .......................vrtdnqksplyttsattgphvestrvvlg----------------------.---E...DTP.....G.....FSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B3MBJ9_DROAN/1637-1749 ..........................ksplyttsagttttgphvestrvvlg----------------------.---E...DTP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4MCP4_DROVI/1631-1741 ............................splyassattsagphvestrvvlg----------------------.---E...DTP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B4KU65_DROMO/1619-1726 ...............................ytssatgstgphvestrvvlg----------------------.---E...DSP.....G.....YSG.HGEIISTQT.VSSKTRT....VE.TIT--Y....K........................TERDGIVETR..V..EQKITIQSDGDpIDHDKALAEAIQEATAMNPDMTVEKIEIQQQT--q..... B7Q520_IXOSC/728-862 ggtmtttvpvvstetrkvayqvdqgagpdraptgatyaatkvttsdvpphdi----------------------.----...---.....-.....VEQ.EGEVVSSQT.ISSKTRT....VE.TVT--Y....K........................MERDGVVETR..V..EQKITIQSDGDpIDHDRALAQAIQEATMMNPDMTVEKIEIQQQ---ssq... B2DBN1_9NEOP/62-182 ................................yttttsstvmgnapfgsmvh-------------AARTSTGPQ.ISES..eAXE.....V.....GQA.EGEVVSSQT.ISSKTRT....VE.TIT--Y....K........................TERNGVVETR..V..EQKITIQSDGDpIDHDRALAEAIQEATAMNPGMTVEKIEIQQQ---stq... A5WUS4_DANRE/20-133 ...................................................r-SEIATKDIPIVHTETKTITYE.SAQP...NAL.....A.....EKE.SGMLLSAQT.ITSETVS....TT.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDTE.IDHDKALAQAIKEAKEQHPDMSVTKVVVHQETEI...... C0PUS5_SALSA/448-561 ....................................................KTEIATKEVPIVHTETKTITYE.AAQL...DGS.....G.....DGE.PGVLMTAQT.ITSESLC....TT.TTTHIT....K........................TLKGGLSETR..I..EKRIVITGDSD.IDHDQALAQAIKEAKEQHPDMSVTRVVVHKETEL...... B0V3D8_DANRE/187-244 ....................................................KTEISTKEVPIVHTETKTITYE.AAQL...DGN.....G.....DGE.PGVLMTAQT.ITSESLC....TT.TTTHIT....K........................----------..-..-----------.----------------------------------...... Q4SC32_TETNG/853-990 ....................................................KTEIATKEVPIVHTETKTITYE.AAQL...DGN.....G.....DSE.PGVLMTAQT.ITSESLC....TT.TTTHIT....KvepaadthfpwflprppslvacpqTLKGGLSETR..I..EKRIVITGDCD.IDHDEALAQAIKEAKEQHPDMSVTRVVVHKETEL...... Q9UG62_HUMAN/53-166 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q6R5J7_HUMAN/264-377 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q5RC68_PONAB/620-733 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... O60642_HUMAN/30-143 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... E41L2_HUMAN/886-999 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B4DJ76_HUMAN/175-288 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q68DV2_HUMAN/628-741 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDGD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q8BSR4_MOUSE/1-108 ....................................................------KEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q811B2_MOUSE/572-683 ...............................tiqdgrrdsksptkatplpae----------------------.-GKI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B6ZHC6_MOUSE/572-683 ...............................tiqdgrrdsksptkatplpae----------------------.-GKI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q9GMU0_MACFA/8-120 ..................................................le--EKNSLRVEGDNIYVRH-SNL.MLEI...DGG.....A.....GGD.SGTLLTAQT.ITSESVS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q80UE4_MOUSE/676-788 ................................egtireeqeecdeeleeepg---------------------Q.GAKI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B6ZHC5_MOUSE/676-788 ................................egtireeqeecdeeleeepg---------------------Q.GAKI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B6ZHC7_MOUSE/664-775 .................................gtireeqeecdeeleeepg---------------------Q.GAKI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q7TPN6_MOUSE/178-291 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... E41L2_MOUSE/869-982 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q80UE5_MOUSE/799-912 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q80UE3_MOUSE/869-982 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... Q3UNQ6_MOUSE/869-982 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISETR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... B6ZHD0_MOUSE/869-982 ...................................................r-TEISTKEVPIVQTETKTITYE.SPQI...DGG.....A.....GGD.SGVLLTAQT.ITSESAS....TT.TTTHIT....K........................TVKGGISVTR..I..EKRIVITGDAA.LDHDQALAQAIREAREQHPDMSVTRVVVHKETEL...... 41_BOVIN/500-614 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... 41_CANFA/693-807 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDSN.....G.....DLD.PGVLLTAQT.ITSETTS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B7Z5L2_HUMAN/81-195 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVNQETEI...... Q1WWM3_HUMAN/625-739 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q59F12_HUMAN/710-824 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... 41_HUMAN/747-861 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q4VB86_HUMAN/505-619 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... A8MU61_HUMAN/435-549 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q4VB87_HUMAN/498-612 ...................................................k-SEIPTKDVPIVHTETKTITYE.AAQT..dDNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... B7Z627_HUMAN/42-152 ..............................lsthspfrtlningqiptgegt----------------------.---D...DNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... Q29RX4_HUMAN/567-675 ................................thspfrtlningqiptgegt----------------------.---D...DNS.....G.....DLD.PGVLLTAQT.ITSETPS....ST.TTTQIT....K........................TVKGGISETR..I..EKRIVITGDAD.IDHDQVLVQAIKEAKEQHPDMSVTKVVVHQETEI...... #=GC seq_cons ...................................................p......hphsllpTpo+TlTYE.usph...Dss.....u.....sh-.sGVLloAQT.ITSETtS....oT.TTTpIT....K........................TVKGGISETR..I..EKRIVITGDuD.IDHDQALAQAI+EA+EQHPDMSVTKVVVHpETEl...... //