LOCUS       NC_022517               8507 bp    DNA     linear   VRL 30-NOV-2014
DEFINITION  Baboon endogenous virus strain M7 proviral DNA, complete genome.
ACCESSION   NC_022517
VERSION     NC_022517.1  GI:725896726
DBLINK      BioProject: PRJNA222253
KEYWORDS    RefSeq.
SOURCE      Baboon endogenous virus strain M7
  ORGANISM  Baboon endogenous virus strain M7
            Viruses; Retro-transcribing viruses; Retroviridae;
            Orthoretrovirinae; Gammaretrovirus; unclassified Gammaretrovirus.
REFERENCE   1
  AUTHORS   Kato,S., Matsuo,K., Nishimura,N., Takahashi,N. and Takano,T.
  TITLE     The entire nucleotide sequence of baboon endogenous virus DNA: A
            chimeric genome structure of murine type C and type D retroviruses
  JOURNAL   Jpn. J. Genet. 62, 127-137 (1987)
REFERENCE   2  (bases 1 to 8507)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (25-NOV-2014) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence is identical to D10032.
            The M7 strain of baboon endogenous virus (BaEV) is a type C
            retrovirus originally isolated from a baboon placenta by
            cocultivation with a human rhabdomyosarcoma cell line, A204. BaEV
            is able to replicate in cultured cells of several diverse mammalian
            species. The nucleotide sequence analysis showed that the structure
            of the BaEV genome is chimeric; the gag-pol region is closely
            related to that of murine type C retroviruses and the env is
            related to that of simian type D retroviruses.
            Shingo Kato
            Keio University School of Medicine
            Department of Microbiology
            35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..8507
                     /organism="Baboon endogenous virus strain M7"
                     /proviral
                     /mol_type="genomic DNA"
                     /strain="M7"
                     /db_xref="taxon:11764"
                     /clone="lambda BEV31"
                     /note="BaEV"
     LTR             1..555
     misc_feature    423
                     /note="capping site"
     primer_bind     544..573
     regulatory      680..683
                     /regulatory_class="other"
                     /note="splice donor sequence"
     gene            985..6168
                     /locus_tag="Q776_gp1"
                     /db_xref="GeneID:22318531"
     CDS             985..6168
                     /locus_tag="Q776_gp1"
                     /note="putative"
                     /codon_start=1
                     /transl_except=(pos:2596..2598,aa:Gln)
                     /product="gag-pol precursor polyprotein"
                     /protein_id="YP_009109689.1"
                     /db_xref="GI:725896727"
                     /db_xref="GeneID:22318531"
                     /translation="MGQTLTTPLSLTLTHFSDVRARAHNLSVGVRKGRWQTFCSSEWP
                     TLHVGWPRDGTFDLSVILQVKTKVMDPGPHGHPDQVAYIITWEDLVRNPPPWVKPFLH
                     TPSTSKSTLLALEVPKNRTLDPPKPVLPDESQQDLLFQDPLPHPPHNPLLEPPPYNSP
                     SPPVLSPVSPTTPSAPTPSSLVSSSTPPSSPAPPELTPRTPPQTPRLRLRRAEGQDGP
                     STWQSSLFPLRTVNRTIQYWPFSASDLYNWKTHNPSFSQDPQALTSLIESILLTHQPT
                     WDDCQQLLQVLLTTEERQRVLLEARKNVPGPGGLPTQLPNEIDEGFPLTRPDWDYETA
                     PGRESLRIYRQALLAGLKGAGKRPTNLAKVRTITQGKDESPAAFMERLLEGFRMYTPF
                     DPEAPEHKATVAMSFIDQAALDIKGKLQRLDGIQTHGLQELVREAEKVYNKRETPEER
                     EARLIKEQEEREDRRDRKRDKHLTKILAAVVTEKRAGKSGETRRRPKVDKDQCAYCKE
                     RGHWIKDCPKRPRDQKKPAPVLTLGEDSEQGCQGSGAPPEPRLTLSVGGHPTTFLVDT
                     GAQHSVLTKANGPLSSRTSWVQGATGRKMHKWTNRRTVNLGQGMVTHSFLVVPECPYP
                     LLGRDLLTKLGAQIHFSEAGAQVLDRDGQPIQILTVSLQDEHRLFDIPVTTSLPDVWL
                     QDFPQAWAETGGLGRAKCQAPIIIDLKPTAVPVSIKQYPMSLEAHMGIRQHIIKFLEL
                     GVLRPCRSPWNTPLLPVKKPGTQDYRPVQDLREINKRTVDIHPTVPNPYNLLSTLKPD
                     YSWYTVLDLKDAFFCLPLAPQSQELFAFEWKDPERGISGQLTWTRLPQGFKNSPTLFD
                     EALHRDLTDFRTQHPEVTLLQYVDDLLLAAPTKKACTQGTRHLLQELGEKGYRASAKK
                     AQICQTKVTYLGYILSEGKRWLTPGRIETVARIPPPRNPREVREFLGTAGFCRLWIPG
                     FAELAAPLYALTKESTPFTWQTEHQLAFEALKKALLSAPALGLPDTSKPFTLFLDERQ
                     GIAKGVLTQKLGPWKRPVAYLSKKLDPVAAGWPPCLRIMAATAMLVKDSAKLTLGQPL
                     TVITPHTLEAIVRQPPDRWITNARLTHYQALLLDTDRVQFGPPVTLNPATLLPVPENQ
                     PSPHDCRQVLAETHGTREDLKDQELPDADHTWYTDGSSYLDSGTRRAGAAVVDGHNTI
                     WAQSLPPGTSAQKAELIALTKALELSKGKKANIYTDSRYAFATAHTHGSIYERRGLLT
                     SEGKEIKNKAEIIALLKALFLPQEVAIIHCPGHQKGQDPVAVGNRQADRVARQAAMAE
                     VLTLATEPDNTSHITIEHTYTSEDQEEARAIGATENKDTRNWEKEGKIVLPQKEALAM
                     IQQMHAWTHLGNRKLKLLIEKTDFLIPRASTLIEQVTSACKVCQQVNAGATRVPAGKR
                     TRGNRPGVYWEIDFTEVKPHYAGYKYLLVFVDTFSGWVEAFPTRQETAHIVAKKILEE
                     IFPRFGLPKVIGSDNGPAFVSQVSQGLARILGINWKLHCAYRPQSSGQVERMNRTIKE
                     TLTKLTLETGLKDWRRLLSLALLRARNTPNRFGLTPYEILYGGPPPLSTLLNSFSPSN
                     SKTDLQARLKGLQAVQAQIWAPLAELYRPGHSQTSHPFQVGDSVYVRRHRSQGLEPRW
                     KGPYIVLLTTPTAIKVDGIATWIHASHAKAAPGTPGPTSSGTWRLRRSEDPLKIRLSR
                     T"
     misc_feature    1027..1359
                     /locus_tag="Q776_gp1"
                     /note="Matrix protein (MA), p15; Region: Gag_MA;
                     pfam01140"
                     /db_xref="CDD:307339"
     misc_feature    1690..2313
                     /locus_tag="Q776_gp1"
                     /note="Gag P30 core shell protein; Region: Gag_p30;
                     pfam02093"
                     /db_xref="CDD:307969"
     mat_peptide     2575..6165
                     /gene="pol"
                     /locus_tag="Q776_gp3"
                     /product="polyprotein"
                     /protein_id="YP_009109692.1"
                     /db_xref="GI:725896730"
     mat_peptide     2575..2958
                     /locus_tag="Q776_gp1"
                     /product="protease"
                     /protein_id="YP_009109693.1"
                     /db_xref="GI:725896731"
     misc_feature    2623..2901
                     /locus_tag="Q776_gp1"
                     /note="Retroviral aspartyl protease; Region: RVP;
                     pfam00077"
                     /db_xref="CDD:306563"
     misc_feature    order(2677..2679,2683..2685,2689..2691,2743..2751,
                     2857..2859)
                     /locus_tag="Q776_gp1"
                     /note="inhibitor binding site; inhibition site"
                     /db_xref="CDD:133159"
     misc_feature    2677..2685
                     /locus_tag="Q776_gp1"
                     /note="catalytic motif [active]"
                     /db_xref="CDD:133159"
     misc_feature    2677..2679
                     /locus_tag="Q776_gp1"
                     /note="Catalytic residue [active]"
                     /db_xref="CDD:133159"
     mat_peptide     2959..4989
                     /locus_tag="Q776_gp1"
                     /product="reverse transcriptase"
                     /protein_id="YP_009109694.1"
                     /db_xref="GI:725896732"
     misc_feature    3124..3771
                     /locus_tag="Q776_gp1"
                     /note="RT_ZFREV_like: A subfamily of reverse
                     transcriptases (RTs) found in sequences similar to the
                     intact endogenous retrovirus ZFERV from zebrafish and to
                     Moloney murine leukemia virus RT. An RT gene is usually
                     indicative of a mobile element such as a...; Region:
                     RT_ZFREV_like; cd03715"
                     /db_xref="CDD:239685"
     misc_feature    order(3142..3147,3247..3249,3289..3300,3307..3312,
                     3523..3525)
                     /locus_tag="Q776_gp1"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:239685"
     misc_feature    order(3400..3417,3520..3525,3616..3618,3622..3627,
                     3757..3762)
                     /locus_tag="Q776_gp1"
                     /note="putative active site [active]"
                     /db_xref="CDD:239685"
     misc_feature    order(3400..3417,3520..3522,3622..3624)
                     /locus_tag="Q776_gp1"
                     /note="putative NTP binding site [chemical binding]; other
                     site"
                     /db_xref="CDD:239685"
     misc_feature    4075..4350
                     /locus_tag="Q776_gp1"
                     /note="Ribonuclease H-like superfamily, including RNase H,
                     HI, HII, HIII, and RNase-like domain IV of spliceosomal
                     protein Prp8; Region: RNase_H_like; cl14782"
                     /db_xref="CDD:326352"
     misc_feature    4513..4935
                     /locus_tag="Q776_gp1"
                     /note="Bel/Pao family of RNase HI in long-term repeat
                     retroelements; Region: RNase_HI_RT_Bel; cd09273"
                     /db_xref="CDD:260005"
     misc_feature    order(4525..4536,4624..4632,4639..4641,4702..4704,
                     4855..4857,4924..4926)
                     /locus_tag="Q776_gp1"
                     /note="RNA/DNA hybrid binding site [nucleotide binding];
                     other site"
                     /db_xref="CDD:260005"
     misc_feature    order(4525..4527,4639..4641,4702..4704,4912..4914)
                     /locus_tag="Q776_gp1"
                     /note="active site"
                     /db_xref="CDD:260005"
     mat_peptide     4990..6165
                     /locus_tag="Q776_gp1"
                     /product="endonuclease"
                     /protein_id="YP_009109695.1"
                     /db_xref="GI:725896733"
     misc_feature    5002..5271
                     /locus_tag="Q776_gp1"
                     /note="His(2)-Cys(2) zinc finger; Region: zf-H2C2;
                     cl07828"
                     /db_xref="CDD:324145"
     misc_feature    5308..5646
                     /locus_tag="Q776_gp1"
                     /note="Integrase core domain; Region: rve; pfam00665"
                     /db_xref="CDD:307008"
     gene            985..2598
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /db_xref="GeneID:22318532"
     CDS             985..2598
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="YP_009109690.1"
                     /db_xref="GI:725896728"
                     /db_xref="GeneID:22318532"
                     /translation="MGQTLTTPLSLTLTHFSDVRARAHNLSVGVRKGRWQTFCSSEWP
                     TLHVGWPRDGTFDLSVILQVKTKVMDPGPHGHPDQVAYIITWEDLVRNPPPWVKPFLH
                     TPSTSKSTLLALEVPKNRTLDPPKPVLPDESQQDLLFQDPLPHPPHNPLLEPPPYNSP
                     SPPVLSPVSPTTPSAPTPSSLVSSSTPPSSPAPPELTPRTPPQTPRLRLRRAEGQDGP
                     STWQSSLFPLRTVNRTIQYWPFSASDLYNWKTHNPSFSQDPQALTSLIESILLTHQPT
                     WDDCQQLLQVLLTTEERQRVLLEARKNVPGPGGLPTQLPNEIDEGFPLTRPDWDYETA
                     PGRESLRIYRQALLAGLKGAGKRPTNLAKVRTITQGKDESPAAFMERLLEGFRMYTPF
                     DPEAPEHKATVAMSFIDQAALDIKGKLQRLDGIQTHGLQELVREAEKVYNKRETPEER
                     EARLIKEQEEREDRRDRKRDKHLTKILAAVVTEKRAGKSGETRRRPKVDKDQCAYCKE
                     RGHWIKDCPKRPRDQKKPAPVLTLGEDSE"
     mat_peptide     985..1320
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /product="p12 protein"
                     /protein_id="YP_009109696.1"
                     /db_xref="GI:725896734"
     misc_feature    1027..1359
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /note="Matrix protein (MA), p15; Region: Gag_MA;
                     pfam01140"
                     /db_xref="CDD:279482"
     mat_peptide     1321..1662
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /product="p15 protein"
                     /protein_id="YP_009109697.1"
                     /db_xref="GI:725896735"
     mat_peptide     1663..2415
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /product="p30 protein"
                     /protein_id="YP_009109698.1"
                     /db_xref="GI:725896736"
     misc_feature    1690..2313
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /note="Gag P30 core shell protein; Region: Gag_p30;
                     pfam02093"
                     /db_xref="CDD:280295"
     mat_peptide     2416..2574
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /product="p10 protein"
                     /protein_id="YP_009109699.1"
                     /db_xref="GI:725896737"
     misc_feature    2488..2538
                     /gene="gag"
                     /locus_tag="Q776_gp2"
                     /note="zinc finger; Region: ZnF_C2HC; smart00343"
                     /db_xref="CDD:197667"
     gene            2575..6165
                     /gene="pol"
                     /locus_tag="Q776_gp3"
                     /db_xref="GeneID:22318529"
     regulatory      5826..5833
                     /regulatory_class="other"
                     /gene="pol"
                     /locus_tag="Q776_gp3"
                     /note="splice acceptor sequence"
     gene            6235..7926
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /db_xref="GeneID:22318530"
     CDS             6235..7926
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /codon_start=1
                     /product="polyprotein"
                     /protein_id="YP_009109691.1"
                     /db_xref="GI:725896729"
                     /db_xref="GeneID:22318530"
                     /translation="MGFTTKIIFLYNLVLVYAGFDDPRKAIELVQKRYGRPCDCSGGQ
                     VSEPPSDRVSQVTCSGKTAYLMPDQRWKCKSIPKDTSPSGPLQECPCNSYQSSVHSSC
                     YTSYQQCRSGNKTYYTATLLKTQTGGTSDVQVLGSTNKLIQSPCNGIKGQSICWSTTA
                     PIHVSDGGGPLDTTRIKSVQRKLEEIHKALYPELQYHPLAIPKVRDNLMVDAQTLNIL
                     NATYNLLLMSNTSLVDDCWLCLKLGPPTPLAIPNFLLSYVTRSSDNISCLIIPPLLVQ
                     PMQFSNSSCLFSPSYNSTEEIDLGHVAFSNCTSITNVTGPICAVNGSVFLCGNNMAYT
                     YLPTNWTGLCVLATLLPDIDIIPGDEPVPIPAIDHFIYRPKRAIQFIPLLAGLGITAA
                     FTTGATGLGVSVTQYTKLSNQLISDVQILSSTIQDLQDQVDSLAEVVLQNRRGLDLLT
                     AEQGGICLALQEKCCFYVNKSGIVRDKIKTLQEELERRRKDLASNPLWTGLQGLLPYL
                     LPFLGPLLTLLLLLTIGPCIFNRLTAFINDKLNIIHAMVLTQQYQVLRTDEEAQD"
     misc_feature    6256..7845
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="ENV polyprotein (coat polyprotein); Region:
                     TLV_coat; pfam00429"
                     /db_xref="CDD:278837"
     mat_peptide     6325..7272
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /product="gp70"
                     /protein_id="YP_009109700.1"
                     /db_xref="GI:725896738"
     mat_peptide     7273..7923
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /product="p20E"
                     /protein_id="YP_009109701.1"
                     /db_xref="GI:725896739"
     misc_feature    7447..7680
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="heptad repeat 1-heptad repeat 2 region (ectodomain)
                     of the transmembrane subunit of human T-cell leukemia
                     virus type 1 (HTLV-1), and related domains; Region:
                     HTLV-1-like_HR1-HR2; cd09851"
                     /db_xref="CDD:197368"
     misc_feature    7462..7578
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="HR1; other site"
                     /db_xref="CDD:197368"
     misc_feature    order(7471..7479,7483..7488,7492..7497,7501..7509,
                     7513..7521,7525..7530,7534..7542,7546..7572,7576..7584,
                     7609..7614,7621..7623,7630..7638,7657..7659,7666..7671,
                     7678..7680)
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="homotrimer interface [polypeptide binding]; other
                     site"
                     /db_xref="CDD:197368"
     misc_feature    7552..7602
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="immunosuppressive region; other site"
                     /db_xref="CDD:197368"
     misc_feature    7558..7560
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="Cl binding site [ion binding]; other site"
                     /db_xref="CDD:197368"
     misc_feature    7603..7626
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="CX(6)C motif; other site"
                     /db_xref="CDD:197368"
     misc_feature    7651..7680
                     /gene="env"
                     /locus_tag="Q776_gp4"
                     /note="HR2; other site"
                     /db_xref="CDD:197368"
     LTR             7953..8507
ORIGIN      
        1 aaatgaaaag taaaactttt aggccctccc cgtaaatggt tctgtttgtt cgtggcgcag
       61 gcagagtttg ttgcaaggct tgatgtaaga ctcgttacta aatgattaac tgcctttgtt
      121 ctgcttctgt aaaactgctt tcccgccctc cgaattgtaa aacaagccct gcctcagccg
      181 gaaattccaa accagtatgc taaaggtggc ggggcccgac cgctgcaacc cagacccaag
      241 gttgcatcag cgaaggaaaa ctgcattccc cagacctccc cggggctagc acctatccca
      301 cccctttgcg tcgccaaata gaaaaagaca cctggcctcg aggttacgaa agaggccaat
      361 caatagcctg tatgcaaata aagcctaaac gctataaaag agatgtatcg ccacaaatcg
      421 gggctctctc tctctctacc acattcctta gagggagggc cctggtgcac cagtaaacga
      481 ctttctgccg aaatttgtgt gttgggtggt tcctcgcgcc gactctcaaa ccctaaggaa
      541 cgtgattcta acatctgggg gctcgtccgg gatttgagag gcggccagag gacaccggcc
      601 ccttttcctt ttcggcagaa accgcgcggc cccggccacc ggtggcggac ggacgacggg
      661 acgactcttg tgtgtagtca ggtactttat ttttgttctg tctttaatct ctgaggtcgg
      721 ccaaccttcg taggagtgta gagggaggac agacgtgtcc tggaccctca cactccgacc
      781 ccgggggacg ccccggcggt cgtctggagg aaggctgatg acaccgtcag cctcctcaaa
      841 tctgaaggca ggttccccct gccatctgaa tcacttgtag tactttggcg ccattctctg
      901 gccgcgcggc tcatctgttt ttgtctggtt tgtgttgtta ctgttgtctt atttatatgt
      961 gtgtatgagc ctaaggacgg gacaatggga cagacgctaa caactcctct atctttgact
     1021 ttgacgcact tttcagacgt ccgggccaga gcccacaatc tttccgtagg agtccgaaaa
     1081 ggacgatggc aaactttctg ctcgtccgag tggcccaccc ttcatgtcgg gtggccccgg
     1141 gacggaactt ttgacctctc cgttattttg caggttaaga caaaggtaat ggatcctggg
     1201 ccgcatggtc acccggacca agtggcctac atcatcacct gggaggatct cgtccgaaat
     1261 cctccgcctt gggtgaaacc ctttctccat accccttcta catccaagtc caccctcctt
     1321 gccctagaag tcccaaagaa ccggaccctg gatccgccta aacccgtact cccggatgag
     1381 tcgcagcaag acctcctctt ccaagaccct ctacctcatc caccacataa tcccctcctg
     1441 gaacccccac cctacaactc accctcgccc cctgtcttgt cccccgtttc tcctaccacc
     1501 ccttctgccc ccactccttc ctctcttgtc tcctcgtcga ccccgccttc ctctccagcc
     1561 ccacctgaac tcacccccag gaccccgcca caaacccccc gtctccgcct ccggcgggcc
     1621 gaaggtcagg atggcccttc cacctggcaa tcttcccttt ttccccttcg cacggtcaac
     1681 cgcacgatcc agtactggcc cttttctgcc tcggacctct ataattggaa aacccataac
     1741 ccctcctttt cccaagaccc ccaggccttg acctcgttga tagaatcaat tctcctcacc
     1801 caccagccta cctgggatga ttgtcaacag cttttgcagg tccttctaac caccgaagaa
     1861 aggcagcgag tcctcctgga agcccggaaa aatgtgccgg ggcctggagg ccttccaacc
     1921 cagctcccca atgaaataga cgagggattt cccctcaccc gcccggactg ggattatgag
     1981 acagcaccgg gtagggagag tctccgaatc tatcgccagg ctctgttggc gggtctcaag
     2041 ggggcaggaa aacgccccac caatttggcc aaggtaagga ctataactca gggaaaagat
     2101 gaaagcccgg cagcctttat ggaaagactt ctggaagggt ttcgaatgta tactccattt
     2161 gatccagaag caccagaaca caaggctacc gtggccatgt cgttcataga tcaggcagca
     2221 ctagacataa aaggaaaact ccaaaggcta gacgggatcc aaactcatgg gctgcaggaa
     2281 ttagtaaggg aggcagaaaa ggtatacaat aaaagggaaa ccccagaaga aagagaagct
     2341 aggcttataa aagaacagga agaacgggaa gatcggagag acagaaaaag agataagcat
     2401 ttaaccaaaa tcctggcagc cgtagtgact gaaaaaaggg caggaaagtc aggggaaaca
     2461 agaaggcggc ctaaagtaga taaggaccag tgcgcctact gcaaagagcg agggcattgg
     2521 atcaaggact gccccaagcg tcctagagac cagaagaaac ccgcccctgt cctcacctta
     2581 ggtgaggaca gcgaataggg gtgtcagggc tctggagccc cccccgagcc ccggctaact
     2641 ctatctgtag gggggcatcc caccaccttc ttggtggaca caggcgccca acactcggtt
     2701 ttgaccaagg caaacggacc cctgtcctct cgtacatctt gggtccaggg ggcaacagga
     2761 agaaagatgc acaaatggac taaccgccgg acagttaacc tagggcaagg aatggtgaca
     2821 cactccttct tggtggtacc tgaatgtccg tacccccttc tggggcgaga tctcctaacc
     2881 aaactcggag ctcagatcca cttctccgag gcaggggccc aggtgttaga ccgagatggc
     2941 caacccatcc aaattttgac tgtgtctctg caagatgaac accggctttt tgacatcccg
     3001 gtcaccacca gcctccctga tgtctggtta caagattttc cccaagcttg ggcggaaacg
     3061 ggaggacttg ggcgggccaa gtgtcaagcc ccaatcataa ttgatctaaa gcccacagcg
     3121 gtgcctgtat ctatcaaaca ataccccatg agcctagaag ctcatatggg cattcggcaa
     3181 cacattatca aatttctaga acttggagtt ttgcgacctt gtcgctcacc ctggaatact
     3241 cctcttctgc cagtaaaaaa gcctggtacc caggattaca ggcccgtcca agatttgaga
     3301 gaaattaata aaagaactgt ggatatccac cctacggtcc ccaatcctta caacttgctc
     3361 agtaccttaa aaccagacta cagctggtat accgtactgg acttaaaaga tgccttcttt
     3421 tgtttacccc tggcccccca aagccaggaa ctatttgcct ttgagtggaa ggaccctgag
     3481 agaggaatct caggccaatt gacctggact cgacttcccc aggggttcaa aaactctccc
     3541 actctcttcg atgaggctct ccacagggac ctcaccgact tccggaccca gcatccagaa
     3601 gtgaccctgc tccagtatgt agatgacctc ctcttggcgg cccccacaaa gaaagcctgc
     3661 acgcaaggta ctaggcatct actccaggaa ctaggtgaga aaggataccg ggcatctgcc
     3721 aagaaggcac aaatttgtca gaccaaggta acttacctgg ggtacatact gagtgaggga
     3781 aaaaggtggc tcacccctgg gcgcatagag actgtggctc gcattccacc gccccggaat
     3841 cccagagagg tgcgtgaatt cctgggaact gctgggttct gtcgcttgtg gatacccggt
     3901 tttgctgaat tggccgcccc cctttacgca ctcaccaagg aaagcacccc tttcacctgg
     3961 cagacagagc atcaattggc ttttgaggca ctaaaaaagg cactcttgtc tgccccagcc
     4021 cttgggttac cggacacctc aaagcccttt accctcttcc tggacgaaag gcaagggatt
     4081 gccaaaggag tcctgaccca aaaattgggg ccttggaaaa gaccggtagc atacctgtcc
     4141 aagaagctgg accctgtggc ggccggctgg cccccatgtc ttcgtatcat ggcagccacc
     4201 gctatgctgg tcaaagactc tgctaagtta acccttgggc agccactgac tgttattact
     4261 ccacatactc tagaggccat agtgcggcag cccccggacc ggtggataac caacgcacgc
     4321 ctaacccact accaggccct cttactggac acggaccgcg tccagtttgg ccctccggtc
     4381 accctaaacc ctgctacgct gctgccggta ccagaaaacc aaccaagccc acacgattgt
     4441 cggcaagtac tggctgagac ccatggaaca cgagaagacc ttaaagacca agagctccca
     4501 gacgcggatc acacctggta cacagacggc agcagttacc ttgactcagg tactcggagg
     4561 gcgggagcag cggtagtaga cggacacaat accatttggg cacaatcact acctcctggc
     4621 acgtctgcac agaaggctga gttaatagca ctaaccaagg ccctagagct gtccaaggga
     4681 aagaaagcta acatttatac tgatagccga tatgcctttg caacggctca tactcatgga
     4741 agtatctatg aaagaagagg tctcctaacc tcagaaggaa aggaaatcaa gaacaaagct
     4801 gaaataattg ccttattaaa ggcccttttt cttcctcaag aagtggctat aattcactgc
     4861 cccgggcatc agaaaggaca ggatccagtc gcagtaggaa acagacaggc tgaccgagtg
     4921 gccaggcaag ccgccatggc ggaagtactg accctagcca cagaacctga caacaccagc
     4981 cacataacta ttgaacatac ttatacctcc gaagaccagg aagaagcaag agccataggg
     5041 gctacagaaa acaaagacac tagaaactgg gaaaaagaag ggaaaatagt ccttccccaa
     5101 aaggaagccc tggcaatgat ccagcagatg catgcctgga cacacttggg taatcgaaag
     5161 ctaaaattgt taattgaaaa aactgacttt ctaatcccaa gggcaagtac actcatagag
     5221 caagtgacat ctgcctgtaa ggtctgtcag caggtaaacg ctggggctac ccgagtgcca
     5281 gcagggaaac ggactcgtgg taaccgcccg ggagtctatt gggaaataga cttcactgaa
     5341 gtaaaacctc actatgctgg gtataagtac ttactagtgt ttgtagatac cttttcagga
     5401 tgggtagaag cctttcccac ccggcaagaa acggcacaca tagtagccaa gaagatccta
     5461 gaagaaatct ttcctagatt tggacttccc aaggtaattg ggtcagacaa cgggccggcc
     5521 ttcgtttccc aggtaagtca ggggctagcc aggatactgg ggattaattg gaaattgcat
     5581 tgtgcttata gaccccagag ctcaggacag gtagagagaa tgaatagaac aataaaagag
     5641 acccttacta aattgacctt agagactggc ttaaaagatt ggagacgcct cctatctcta
     5701 gctctattaa gagcccggaa tacgcctaac cgctttgggc tcactccata tgaaatcctc
     5761 tatggaggac ctcccccttt gtcaacctta cttaactcct tttctccctc caattctaag
     5821 actgacctac aggcccggct aaaaggacta caagcagtac aggcccaaat ctgggccccc
     5881 ttggcagaac tgtaccggcc aggacattcg cagaccagcc accccttcca ggtgggggac
     5941 tccgtctacg ttagacgaca ccgttctcag ggactggagc ctcggtggaa aggaccctac
     6001 attgttctcc tgaccacacc cacagccata aaggttgacg gaatcgccac gtggattcac
     6061 gcatcccacg ccaaggctgc tccagggacg cctggaccga cgtcgtccgg aacttggaga
     6121 ctccgccgct ccgaggaccc ccttaagata agactctcac gcacttgact tcttacttgc
     6181 ccttgtcctc ctaccccgcg ccgtacatag cagtaacccc tcatatagtc caagatggga
     6241 ttcacaacaa agataatctt cttatacaac ctagtactgg tctacgcggg gtttgacgac
     6301 cctcgcaaag ccatagaact agtacaaaag cgatatggcc gaccatgcga ttgcagcgga
     6361 ggacaagtgt ccgagccccc gtcagacagg gtcagtcaag tgacttgctc aggcaagaca
     6421 gcttacttaa tgcccgacca aagatggaaa tgtaagtcaa ttccaaaaga cacctcccca
     6481 agcgggccac tccaagagtg cccctgtaat tcttaccagt cctcagtaca cagttcttgt
     6541 tatacctcat accaacaatg cagatcaggc aataagacat attatacggc tactctgcta
     6601 aaaacacaaa ctgggggcac cagtgatgta caagtattag gatccaccaa caaacttata
     6661 caatctccct gtaatggcat aaaagggcag tctatttgct ggagcactac agctcctatc
     6721 cacgtctctg atggaggagg tccattagac accacaagaa ttaaaagtgt tcagagaaaa
     6781 ctggaagaaa ttcataaagc cctatatcct gaacttcagt atcacccttt ggccatacct
     6841 aaggttagag ataacctcat ggtcgatgcc cagactttaa acattctcaa tgccacttac
     6901 aacttactcc taatgtccaa cacgagccta gtggacgact gttggctttg tttaaaatta
     6961 ggtcccccta ctcccctcgc aatacctaac ttcctattat cctacgtgac tcgctcctcg
     7021 gataatatct cttgtttaat aattcccccc cttctagttc aaccgatgca gttttccaat
     7081 tcatcttgcc tcttttcccc ctcctacaac agtacagaag aaatagatct aggccatgtt
     7141 gccttcagca actgtacctc cataaccaat gtcaccggtc ccatatgcgc tgtaaatggt
     7201 tcggtctttc tctgtggcaa taacatggca tacacttatc tacccacgaa ctggacgggg
     7261 ctttgcgtcc tagcaactct cctccccgac attgacatca ttcccggaga tgaaccggtc
     7321 cccatccctg ctattgatca ttttatatat agacctaaac gggccataca gtttattcct
     7381 ttactagcag ggctagggat caccgcagcc ttcacaacag gagctacagg cctaggtgtc
     7441 tctgtgaccc aatatacaaa attatctaat cagctaattt ctgatgtaca aatcttatct
     7501 agcaccatac aagatctgca agatcaagta gactcattag ccgaagtggt tctccagaac
     7561 agaagggggc tagatctact tacagcagaa caaggaggaa tctgtttagc cctgcaagaa
     7621 aaatgctgct tttatgttaa caagtcaggg attgtgagag acaaaataaa aaccttacaa
     7681 gaagaactag aaagacgtag aaaagatcta gcttccaacc cactttggac tgggcttcaa
     7741 gggctcctcc cttacctcct gccctttctt ggccctctac ttaccctcct gctcttactc
     7801 accattgggc cgtgcatttt taaccgtcta accgctttta ttaatgataa gttaaacata
     7861 atacacgcta tggtgctaac ccaacagtat caggtgctca gaaccgatga agaagctcaa
     7921 gattgagcct ctaagacaca agaaaagggg gaaaatgaaa agtaaaactt ttaggccctc
     7981 cccgtaaatg gttctgtttg ttcgtggcgc aggcagagtt tgttgcaagg cttgatgtaa
     8041 gactcgttac taaatgatta actgcctttg ttctgcttct gtaaaactgc tttcccgccc
     8101 tccgaattgt aaaacaagcc ctgcctcagc cggaaattcc aaaccagtat gctaaaggtg
     8161 gcggggcccg accgctgcaa cccagaccca aggttgcatc agcgaaggaa aactgcattc
     8221 cccagacctc cccggggcta gcacctatcc cacccctttg cgtcgccaaa tagaaaaaga
     8281 cacctggcct cgaggttacg aaagaggcca atcaatagcc tgtatgcaaa taaagcctaa
     8341 acgctataaa agagatgtat cgccacaaat cggggctctc tctctctcta ccacattcct
     8401 tagagggagg gccctggtgc accagtaaac gactttctgc cgaaatttgt gtgttgggtg
     8461 gttcctcgcg ccgactctca aaccctaagg aacgtgattc taacatc
//
