1: Ferreira ME, Rojas de Arias A, Yaluff G, de Bilbao NV, Nakayama H, Torres S, Schinini A, Guy I, Heinzen H, Fournet A. Antileishmanial activity of furoquinolines and coumarins from Helietta apiculata. Phytomedicine. 2010 Apr;17(5):375-378. Epub 2009 Oct 29. PubMed PMID: 19879121. 2: Nakayama H, Nakanishi J, Shimizu T, Yoshino Y, Iwai H, Kaneko S, Horiike Y, Yamaguchi K. Silane coupling agent bearing a photoremovable succinimidyl carbonate for patterning amines on glass and silicon surfaces with controlled surface densities. Colloids Surf B Biointerfaces. 2010 Mar 1;76(1):88-97. Epub 2009 Oct 20. PubMed PMID: 19910170. 3: Xiaoli C, Ziyang L, Shimaoka T, Nakayama H, Ying Z, Xiaoyan C, Komiya T, Ishizaki T, Youcai Z. Characteristics of environmental factors and their effects on CH4 and CO2 emissions from a closed landfill: an ecological case study of Shanghai. Waste Manag. 2010 Mar;30(3):446-51. Epub 2009 Oct 31. PubMed PMID: 19880303. 4: Arikuma Y, Nakayama H, Morita T, Kimura S. Electron Hopping over 100 A Along an alpha Helix. Angew Chem Int Ed Engl. 2010 Feb 12;49(10):1800-1804. [Epub ahead of print] PubMed PMID: 20155768. 5: Tsuboi M, Uchida K, Park ES, Kotera Y, Seki T, Takahashi M, Nakayama H. Systemic T Cell Large Granular Lymphocyte Lymphoma with Multifocal White Matter Degeneration in the Brain of a Japanese Domestic Cat. J Vet Med Sci. 2010 Feb 2. [Epub ahead of print] PubMed PMID: 20124761. 6: Nakayama H, Takakuda K, Matsumoto HN, Miyata A, Baba O, Tabata MJ, Ushiki T, Oda T, McKee MD, Takano Y. Effects of altered bone remodeling and retention of cement lines on bone quality in osteopetrotic aged c-Src-deficient mice. Calcif Tissue Int. 2010 Feb;86(2):172-83. PubMed PMID: 20063091. 7: Ito H, Nakayama H. [Surgical management of pulmonary metastases.]. Gan To Kagaku Ryoho. 2010 Feb;37(2):200-3. Japanese. PubMed PMID: 20154473. 8: Sugahara S, Oshiro Y, Nakayama H, Fukuda K, Mizumoto M, Abei M, Shoda J, Matsuzaki Y, Thono E, Tokita M, Tsuboi K, Tokuuye K. Proton beam therapy for large hepatocellular carcinoma. Int J Radiat Oncol Biol Phys. 2010 Feb 1;76(2):460-6. Epub 2009 May 7. PubMed PMID: 19427743. 9: Kawase T, Okuda K, Kogami H, Nakayama H, Nagata M, Yoshie H. Osteogenic activity of human periosteal sheets cultured on salmon collagen-coated ePTFE meshes. J Mater Sci Mater Med. 2010 Feb;21(2):731-9. Epub 2009 Oct 16. PubMed PMID: 19834787. 10: Ide T, Uchida K, Tamura S, Nakayama H. Histiocytic sarcoma in the brain of a cat. J Vet Med Sci. 2010 Feb;72(1):99-102. Epub 2009 Nov 13. PubMed PMID: 19915332. 11: Nishimura N, Nakayama H, Yoshizumi S, Miyoshi M, Tonoike H, Shirasaki Y, Kojima K, Ishida S. Detection of noroviruses in fecal specimens by direct RT-PCR without RNA purification. J Virol Methods. 2010 Feb;163(2):282-6. Epub 2009 Oct 28. PubMed PMID: 19878699. 12: Hokari S, Koya T, Shimaoka Y, Nakayama H, Terada M, Suzuki E. [Interstitial pneumonia associated with stiff-person syndrome]. Nihon Kokyuki Gakkai Zasshi. 2010 Feb;48(2):162-5. Japanese. PubMed PMID: 20184250. 13: Dong M, He XJ, Tulayakul P, Li JY, Dong KS, Manabe N, Nakayama H, Kumagai S. The toxic effects and fate of intravenously administered zearalenone in goats. Toxicon. 2010 Feb-Mar;55(2-3):523-30. Epub 2009 Oct 13. PubMed PMID: 19825386. 14: Dittmann K, Mayer C, Rodemann HP, Mücke R, Seegenschmiedt MH, Heyd R, Schäfer U, Prott FJ, Glatzel M, Micke O, Adamietz B, Schulz-Wendtland R, Alibek S, Uder M, Sauer R, Ott O, Keilholz L, Heyd R, Dorn AP, Herkströter M, Rödel C, Müller-Schimpfle M, Fraunholz I, Wolff HA, Gaedcke J, Jung K, Hermann RM, Rothe H, Schirmer M, Liersch T, Herrmann MK, Hennies S, Rave-Fränk M, Hess CF, Christiansen H, Mizumoto M, Nakayama H, Tokita M, Sugahara S, Hashii H, Sakae T, Tsuboi K, Sakurai H, Tokuuye K, Geinitz H, Thamm R, Scholz C, Heinrich C, Prause N, Kerndl S, Keller M, Busch R, Molls M, Zimmermann FB. Strahlenther Onkol. 2010 Jan 28. [Epub ahead of print] German. PubMed PMID: 20130825. 15: Takeuchi Y, Fujino Y, Goto-Koshino Y, Ohno K, Uchida K, Nakayama H, Tsujimoto H. Long Term Survival of Primary Skeletal Muscle Lymphoma in a Miniature Dachshund. J Vet Med Sci. 2010 Jan 22. [Epub ahead of print] PubMed PMID: 20093801. 16: Tochitani T, Kanemitsu H, Yamauchi H, Uchida K, Nakayama H. 5-azacytidine, a chemotherapeutic drug, induces TRAIL-mediated apoptosis in mouse thymocytes in vivo. Exp Toxicol Pathol. 2010 Jan 19. [Epub ahead of print] PubMed PMID: 20092982. 17: Moriguchi M, Takayama T, Nakamura M, Aramaki O, Higaki T, Nakayama H, Ohkubo T, Fujii M. Phase I/II study of a fine-powder formulation of cisplatin for transcatheter arterial chemoembolization in hepatocellular carcinoma. Hepatol Res. 2010 Jan 11. [Epub ahead of print] PubMed PMID: 20070392. 18: Ito S, Kusuhara H, Kuroiwa Y, Wu C, Moriyama Y, Inoue K, Kondo T, Yuasa H, Nakayama H, Horita S, Sugiyama Y. Potent and specific inhibition of mMate1-mediated efflux of type I organic cations in the liver and kidney by pyrimethamine. J Pharmacol Exp Ther. 2010 Jan 11. [Epub ahead of print] PubMed PMID: 20065018. 19: Nakayama H, Sugahara S, Tokita M, Satoh H, Tsuboi K, Ishikawa S, Tokuuye K. Proton Beam Therapy for Patients with Medically Inoperable Stage I Non-Small-Cell Lung Cancer at the University of Tsukuba. Int J Radiat Oncol Biol Phys. 2010 Jan 5. [Epub ahead of print] PubMed PMID: 20056349. 20: Teshima K, Murakami R, Tomitaka E, Nomura T, Toya R, Hiraki A, Nakayama H, Hirai T, Shinohara M, Oya N, Yamashita Y. Radiation-induced parotid gland changes in oral cancer patients: correlation between parotid volume and saliva production. Jpn J Clin Oncol. 2010 Jan;40(1):42-6. Epub 2009 Oct 6. PubMed PMID: 19812062. 21: Nakayama H, Shibuya K, Kimura M, Ueda M, Iwabuchi S. Histopathological study of candidal infection in the central nervous system. Nippon Ishinkin Gakkai Zasshi. 2010;51(1):31-45. PubMed PMID: 20185869. 22: Mizumoto M, Nakayama H, Tokita M, Sugahara S, Hashii H, Sakae T, Tsuboi K, Sakurai H, Tokuuye K. Technical considerations for noncoplanar proton-beam therapy of patients with tumors proximal to the optic nerve. Strahlenther Onkol. 2010 Jan;186(1):36-9. Epub 2009 Dec 28. PubMed PMID: 20082186. 23: Sakuma Y, Takeuchi T, Nakamura Y, Yoshihara M, Matsukuma S, Nakayama H, Ohgane N, Yokose T, Kameda Y, Tsuchiya E, Miyagi Y. Lung adenocarcinoma cells floating in lymphatic vessels resist anoikis by expressing phosphorylated Src. J Pathol. 2009 Dec 18. [Epub ahead of print] PubMed PMID: 20146241. 24: Kuraishi T, Nakagawa Y, Nagaosa K, Hashimoto Y, Ishimoto T, Moki T, Fujita Y, Nakayama H, Dohmae N, Shiratsuchi A, Yamamoto N, Ueda K, Yamaguchi M, Awasaki T, Nakanishi Y. Pretaporter, a Drosophila protein serving as a ligand for Draper in the phagocytosis of apoptotic cells. EMBO J. 2009 Dec 16;28(24):3868-78. Epub . PubMed PMID: 19927123; PubMed Central PMCID: PMC2797060. 25: Murakami S, Saito H, Sakuma Y, Mizutani Y, Ishikawa Y, Kondou T, Oshita F, Yokose T, Kameda Y, Suga Y, Ito H, Tsuboi M, Nakayama H, Noda K, Yamada K. Correlation of (18)F-fluorodeoxyglucose uptake on positron emission tomography with Ki-67 index and pathological invasive area in lung adenocarcinomas 30mm or less in size. Eur J Radiol. . [Epub ahead of print] PubMed PMID: 20005653. 26: Murata K, Nishimura S, Kuniyasu A, Nakayama H. Three-dimensional structure of the {alpha}1-{beta} complex in the skeletal muscle dihydropyridine receptor by single-particle electron microscopy. J Electron Microsc (Tokyo). 2009 Dec 7. [Epub ahead of print] PubMed PMID: 19995890. 27: Wada N, Sugino K, Mimura T, Nagahama M, Kitagawa W, Shibuya H, Ohkuwa K, Nakayama H, Hirakawa S, Yukawa N, Rino Y, Masuda M, Ito K. Treatment strategy of papillary thyroid carcinoma in children and adolescents: clinical significance of the initial nodal manifestation. Ann Surg Oncol. 2009 Dec;16(12):3442-9. Epub 2009 Sep 24. PubMed PMID: 19777194. 28: Nakayama H, Sugahara S, Tokita M, Fukuda K, Mizumoto M, Abei M, Shoda J, Sakurai H, Tsuboi K, Tokuuye K. Proton beam therapy for hepatocellular carcinoma: the University of Tsukuba experience. Cancer. 2009 Dec 1;115(23):5499-506. PubMed PMID: 19645024. 29: Nakayama H, Zhao J, Ei-Fakhrany A, Isosaki M, Satoh H, Kyotani Y, Yoshizumi M. Neuroprotective effects of pramipexole against tunicamycin-induced cell death in PC12 cells. Clin Exp Pharmacol Physiol. 2009 Dec;36(12):1183-5. Epub 2009 Jun 9. PubMed PMID: 19515063. 30: Nakayama H, Bodi I, Correll RN, Chen X, Lorenz J, Houser SR, Robbins J, Schwartz A, Molkentin JD. alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice. J Clin Invest. 2009 Dec;119(12):3787-96. doi: 10.1172/JCI39724. Epub 2009 Nov 16. PubMed PMID: 19920353; PubMed Central PMCID: PMC2786799. 31: Makino T, Kinoshita J, Arakawa S, Ito K, Ando Y, Yamoto T, Teranishi M, Sanbuissho A, Nakayama H. Comprehensive analysis of hepatic gene and protein expression profiles on phenobarbital- or clofibrate-induced hepatic hypertrophy in dogs. J Toxicol Sci. 2009 Dec;34(6):647-61. PubMed PMID: 19952500. 32: Sugahara S, Nakayama H, Fukuda K, Mizumoto M, Tokita M, Abei M, Shoda J, Matsuzaki Y, Thono E, Tsuboi K, Tokuuye K. Proton-beam therapy for hepatocellular carcinoma associated with portal vein tumor thrombosis. Strahlenther Onkol. 2009 Dec;185(12):782-8. Epub . PubMed PMID: 20013087. 33: Soejima H, Oe Y, Nakayama H, Matsuo K, Fukunaga T, Sugamura K, Kawano H, Sugiyama S, Shinohara M, Izumi Y, Ogawa H. Periodontal status and Prevotella intermedia antibody in acute coronary syndrome. Int J Cardiol. 2009 Nov 12;137(3):304-6. Epub 2008 Aug 6. PubMed PMID: 18684535. 34: Tajiri Y, Kato T, Nakayama H, Yamada K. Reduction of Skeletal Muscle, Especially in Lower Limbs, in Japanese Type 2 Diabetic Patients With Insulin Resistance and Cardiovascular Risk Factors. Metab Syndr Relat Disord. 2009 Nov 9. [Epub ahead of print] PubMed PMID: 19900156. 35: Nakayama H, Yagi M, Yoshiya S. Intraosseous ganglion in the subchondral region of the lateral femoral condyle in an 11-year-old girl: a case report. Sports Med Arthrosc Rehabil Ther Technol. 2009 Nov 5;1(1):25. PubMed PMID: 19891774; PubMed Central PMCID: PMC2776581. 36: Kurishima K, Satoh H, Kagohashi K, Homma S, Nakayama H, Ohara G, Ishikawa H, Hizawa N. Patients with lung cancer with metachronous or synchronous gastric cancer. Clin Lung Cancer. 2009 Nov;10(6):422-5. PubMed PMID: 19900860. 37: Handa T, Ishikawa H, Shimizu K, Kawamura R, Nakayama H, Sawada K. A novel apparatus for testing binocular function using the 'CyberDome' three-dimensional hemispherical visual display system. Eye (Lond). 2009 Nov;23(11):2094-8. Epub 2008 Dec 12. PubMed PMID: 19079143. 38: Shibui Y, He XJ, Uchida K, Nakayama H. MPTP-induced neuroblast apoptosis in the subventricular zone is not regulated by dopamine or other monoamine transporters. Neurotoxicology. 2009 Nov;30(6):1036-44. Epub 2009 Jul 16. PubMed PMID: 19616025. 39: Taoka M, Yamauchi Y, Nobe Y, Masaki S, Nakayama H, Ishikawa H, Takahashi N, Isobe T. An analytical platform for mass spectrometry-based identification and chemical analysis of RNA in ribonucleoprotein complexes. Nucleic Acids Res. 2009 Nov;37(21):e140. Epub . PubMed PMID: 19740761; PubMed Central PMCID: PMC2790879. 40: Hisatsune A, Kawasaki M, Nakayama H, Mikami Y, Miyata T, Isohama Y, Katsuki H, Kim KC. Internalization of MUC1 by anti-MUC1 antibody from cell membrane through the macropinocytotic pathway. Biochem Biophys Res Commun. 2009 Oct 30;388(4):677-82. Epub 2009 Aug 14. PubMed PMID: 19683510. 41: Ichihashi Y, Masuda N, Tsuge M, Nakayama H, Shiraki A, Shimobaba T, Ito T. One-unit system to reconstruct a 3-D movie at a video-rate via electroholography. Opt Express. 2009 Oct 26;17(22):19691-7. doi: 10.1364/OE.17.019691. PubMed PMID: 19997189. 42: Iwabuchi K, Nakayama H, Iwahara C, Takamori K. Significance of glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction. FEBS Lett. 2009 Oct 21. [Epub ahead of print] PubMed PMID: 19852959. 43: Arakawa T, Kawano Y, Katayama Y, Nakayama H, Dohmae N, Yohda M, Odaka M. Structural basis for catalytic activation of thiocyanate hydrolase involving metal-ligated cysteine modification. J Am Chem Soc. 2009 Oct 21;131(41):14838-43. PubMed PMID: 19785438. 44: Takayama K, Mizowaki T, Kokubo M, Kawada N, Nakayama H, Narita Y, Nagano K, Kamino Y, Hiraoka M. Initial validations for pursuing irradiation using a gimbals tracking system. Radiother Oncol. 2009 Oct;93(1):45-9. Epub 2009 Aug 21. PubMed PMID: 19699544. 45: Otabe S, Nakayama H, Fukutani T, Yuan X, Wada N, Hashinaga T, Mitsui A, Kato T, Inada C, Tajiri Y, Yamada K. Excessive maternal transmission of diabetes in Japanese families with young-onset type 2 diabetes and insulin secretion defect according to clinical features. Acta Diabetol. 2009 Sep 29. [Epub ahead of print] PubMed PMID: 19787289. 46: Nakayama H, Kawase T, Kogami H, Okuda K, Inoue H, Oda T, Hayama K, Tsuchimochi M, Wolff LF. Evaluation by Bone Scintigraphy of Osteogenic Activity of Commercial Bioceramics (Porous {beta}-TCP and HAp Particles) Subcutaneously Implanted in Rats. J Biomater Appl. 2009 Sep 2. [Epub ahead of print] PubMed PMID: 19726531. 47: Wada N, Sugino K, Mimura T, Nagahama M, Kitagawa W, Shibuya H, Ohkuwa K, Nakayama H, Hirakawa S, Rino Y, Masuda M, Ito K. Pediatric differentiated thyroid carcinoma in stage I: risk factor analysis for disease free survival. BMC Cancer. 2009 Sep 1;9:306. PubMed PMID: 19723317; PubMed Central PMCID: PMC2746228. 48: Shinriki S, Jono H, Ota K, Ueda M, Kudo M, Ota T, Oike Y, Endo M, Ibusuki M, Hiraki A, Nakayama H, Yoshitake Y, Shinohara M, Ando Y. Humanized anti-interleukin-6 receptor antibody suppresses tumor angiogenesis and in vivo growth of human oral squamous cell carcinoma. Clin Cancer Res. 2009 Sep 1;15(17):5426-34. Epub 2009 Aug 25. PubMed PMID: 19706815. 49: Nakayama H, Ito H, Kato Y, Tsuboi M. Ultrasonic scalpel for sealing of the thoracic duct: evaluation of effectiveness in an animal model. Interact Cardiovasc Thorac Surg. 2009 Sep;9(3):399-401. Epub 2009 Jun 29. PubMed PMID: 19564208. 50: Satoh H, Iwashima A, Endo Y, Nakayama H, Hasegawa T, Suzuki E. [Effect of proactive use of inhaled procaterol on dyspnea in daily activities and quality of life in patients with chronic obstructive pulmonary disease]. Nihon Kokyuki Gakkai Zasshi. 2009 Sep;47(9):772-80. Japanese. PubMed PMID: 19827580. 51: Tanaka M, Takahata Y, Nakayama H, Nakatani M, Tahara M. Altered carbohydrate metabolism in the storage roots of sweet potato plants overexpressing the SRF1 gene, which encodes a Dof zinc finger transcription factor. Planta. 2009 Sep;230(4):737-46. Epub 2009 Jul 19. PubMed PMID: 19618208. 52: Kurishima K, Kagohashi K, Nakayama H, Satoh H. Incidentally detected lung cancer. South Med J. 2009 Sep;102(9):986. PubMed PMID: 19668041. 53: Tsukimoto I, Tawa A, Horibe K, Tabuchi K, Kigasawa H, Tsuchida M, Yabe H, Nakayama H, Kudo K, Kobayashi R, Hamamoto K, Imaizumi M, Morimoto A, Tsuchiya S, Hanada R. Risk-stratified therapy and the intensive use of cytarabine improves the outcome in childhood acute myeloid leukemia: the AML99 trial from the Japanese Childhood AML Cooperative Study Group. J Clin Oncol. 2009 Aug 20;27(24):4007-13. Epub 2009 Jul 20. PubMed PMID: 19620491. 54: Mizumoto M, Tsuboi K, Igaki H, Yamamoto T, Takano S, Oshiro Y, Hayashi Y, Hashii H, Kanemoto A, Nakayama H, Sugahara S, Sakurai H, Matsumura A, Tokuuye K. Phase I/II Trial of Hyperfractionated Concomitant Boost Proton Radiotherapy for Supratentorial Glioblastoma Multiforme. Int J Radiat Oncol Biol Phys. 2009 Aug 19. [Epub ahead of print] PubMed PMID: 19695794. 55: Takano A, Ishikawa N, Nishino R, Masuda K, Yasui W, Inai K, Nishimura H, Ito H, Nakayama H, Miyagi Y, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y. Identification of nectin-4 oncoprotein as a diagnostic and therapeutic target for lung cancer. Cancer Res. 2009 Aug 15;69(16):6694-703. PubMed PMID: 19679554. 56: Ichihashi Y, Nakayama H, Ito T, Masuda N, Shimobaba T, Shiraki A, Sugie T. HORN-6 special-purpose clustered computing system for electroholography. Opt Express. 2009 Aug 3;17(16):13895-903. PubMed PMID: 19654797. 57: Sonnino S, Prinetti A, Nakayama H, Yangida M, Ogawa H, Iwabuchi K. Role of very long fatty acid-containing glycosphingolipids in membrane organization and cell signaling: the model of lactosylceramide in neutrophils. Glycoconj J. 2009 Aug;26(6):615-21. Epub 2008 Nov 18. Review. PubMed PMID: 19015977. 58: Numazaki R, Miyagi E, Konnai K, Ikeda M, Yamamoto A, Onose R, Kato H, Okamoto N, Hirahara F, Nakayama H. Analysis of stage IVB endometrial carcinoma patients with distant metastasis: a review of prognoses in 55 patients. Int J Clin Oncol. 2009 Aug;14(4):344-50. Epub 2009 Aug 25. PubMed PMID: 19705246. 59: Ide T, Uchida K, Morozumi M, Nakayama H. Hamartoma in the medulla oblongata with marked mineral deposits in a dog. J Vet Med Sci. 2009 Aug;71(8):1097-100. PubMed PMID: 19721366. 60: Saito N, Hatori T, Aoki K, Hayashi M, Hirata Y, Sato K, Nakayama H, Harashina J, Murata N, Zhang ZA, Nonaka H, Shibuya K, Iwabuchi S. Dynamics of global gene expression changes during brain metastasis formation. Neuropathology. 2009 Aug;29(4):389-97. Epub 2008 Nov 19. PubMed PMID: 19019174. 61: Nomura T, Murakami R, Toya R, Teshima K, Nakahara A, Hirai T, Hiraki A, Nakayama H, Yoshitake Y, Ota K, Obayashi T, Yamashita Y, Oya N, Shinohara M. Phase II Study of Preoperative Concurrent Chemoradiation Therapy with S-1 in Patients with T4 Oral Squamous Cell Carcinoma. Int J Radiat Oncol Biol Phys. 2009 Jul 21. [Epub ahead of print] PubMed PMID: 19628343. 62: Kawahara K, Nishi K, Suenobu M, Ohtsuka H, Maeda A, Nagatomo K, Kuniyasu A, Staufenbiel M, Nakagomi M, Shudo K, Nakayama H. Oral administration of synthetic retinoid Am80 (Tamibarotene) decreases brain beta-amyloid peptides in APP23 mice. Biol Pharm Bull. 2009 Jul;32(7):1307-9. PubMed PMID: 19571405. 63: Fujita K, Nakayama H, Ichikawa W, Yamamoto W, Endo H, Nagashima F, Tanaka R, Miya T, Sunakawa Y, Yamashita K, Mizuno K, Ishida H, Araki K, Narabayashi M, Miwa K, Ando Y, Akiyama Y, Kawara K, Hirose T, Sasaki Y. Pharmacokinetics of 5-fluorouracil in elderly Japanese patients with cancer treated with S-1 (a combination of tegafur and dihydropyrimidine dehydrogenase inhibitor 5-chloro-2,4-dihydroxypyridine). Drug Metab Dispos. 2009 Jul;37(7):1375-7. Epub 2009 Apr 23. PubMed PMID: 19389859. 64: Watanabe T, Maeda K, Kondo T, Nakayama H, Horita S, Kusuhara H, Sugiyama Y. Prediction of the hepatic and renal clearance of transporter substrates in rats using in vitro uptake experiments. Drug Metab Dispos. 2009 Jul;37(7):1471-9. Epub 2009 Apr 13. PubMed PMID: 19364828. 65: Ueno T, Torimura T, Nakamura T, Sivakumar R, Nakayama H, Otabe S, Yuan X, Yamada K, Hashimoto O, Inoue K, Koga H, Sata M. Epigallocatechin-3-gallate improves nonalcoholic steatohepatitis model mice expressing nuclear sterol regulatory element binding protein-1c in adipose tissue. Int J Mol Med. 2009 Jul;24(1):17-22. PubMed PMID: 19513529. 66: Fukumitsu N, Sugahara S, Nakayama H, Fukuda K, Mizumoto M, Abei M, Shoda J, Thono E, Tsuboi K, Tokuuye K. A prospective study of hypofractionated proton beam therapy for patients with hepatocellular carcinoma. Int J Radiat Oncol Biol Phys. 2009 Jul 1;74(3):831-6. Epub 2009 Mar 21. PubMed PMID: 19304408. 67: Tachiki K, Kodama Y, Nakayama H, Shinmyo A. Determination of the in vivo distribution of nuclear matrix attachment regions using a polymerase chain reaction-based assay in Arabidopsis thaliana. J Biosci Bioeng. 2009 Jul;108(1):11-9. PubMed PMID: 19577185. 68: Nakayama H, Kikuta F, Takeda H. A pilot study on effectiveness of music therapy in hospice in Japan. J Music Ther. 2009 Summer;46(2):160-72. PubMed PMID: 19463033. 69: Sakuma Y, Okamoto N, Saito H, Yamada K, Yokose T, Kiyoshima M, Asato Y, Amemiya R, Saitoh H, Matsukuma S, Yoshihara M, Nakamura Y, Oshita F, Ito H, Nakayama H, Kameda Y, Tsuchiya E, Miyagi Y. A logistic regression predictive model and the outcome of patients with resected lung adenocarcinoma of 2 cm or less in size. Lung Cancer. 2009 Jul;65(1):85-90. Epub 2008 Nov 22. PubMed PMID: 19027984. 70: Nakayama H, Otabe S, Yuan X, Ueno T, Hirota N, Fukutani T, Wada N, Hashinaga T, Yamada K. Effects of adiponectin transgenic expression in liver of nonalcoholic steatohepatitis model mice. Metabolism. 2009 Jul;58(7):901-8. PubMed PMID: 19394977. 71: Kanemitsu H, Yamauchi H, Komatsu M, Yamamoto S, Okazaki S, Uchida K, Nakayama H. 6-mercaptopurine (6-MP) induces p53-mediated apoptosis of neural progenitor cells in the developing fetal rodent brain. Neurotoxicol Teratol. 2009 Jul-Aug;31(4):198-202. Epub 2009 Mar 10. PubMed PMID: 19281843. 72: Yamaguchi M, Nakayama H, Yamada K, Imai H. Ultralow refractive index coatings consisting of mesoporous silica nanoparticles. Opt Lett. 2009 Jul 1;34(13):2060-2. PubMed PMID: 19571999. 73: Isozaki E, Tobisawa S, Nishizawa M, Nakayama H, Fukui K, Takanishi A. [Experimental vocal cord abduction impairment with an artificial vocal cord]. Rinsho Shinkeigaku. 2009 Jul;49(7):407-13. Japanese. PubMed PMID: 19715168. 74: Suganuma N, Wada N, Arai H, Nakayama H, Fujii K, Masudo K, Yukawa N, Rino Y, Masuda M, Imada T. Chest wall resection and reconstruction using titanium micromesh covered with Marlex mesh for metastatic follicular thyroid carcinoma: a case report. J Med Case Reports. 2009 Jun 8;3:7259. PubMed PMID: 19830154; PubMed Central PMCID: PMC2726531. 75: Qin T, Iida K, Hirakawa H, Shiota S, Nakayama H, Yoshida S. Conjugative plasmid pLD-TEX-KL promotes growth of host bacterium Legionella dumoffii at low temperatures. Arch Microbiol. 2009 Jun;191(6):543-51. Epub 2009 May 5. PubMed PMID: 19415237. 76: Ide K, Setoguchi-Mukai A, Nakagawa T, Uetsuka K, Nakayama H, Fujino Y, Ohno K, Tsujimoto H. Disseminated histiocytic sarcoma with excessive hemophagocytosis in a cat. J Vet Med Sci. 2009 Jun;71(6):817-20. PubMed PMID: 19578295. 77: Nakayama H, Morita T, Kimura S. Dipole effects on molecular and electronic structures in a novel conjugate of oligo(phenyleneethynylene) and helical peptide. Phys Chem Chem Phys. 2009 May 28;11(20):3967-76. Epub 2009 Mar 10. PubMed PMID: 19440626. 78: Uetani T, Nakayama H, Okayama H, Okura T, Higaki J, Inoue H, Higashiyama S. Insufficiency of pro-heparin-binding epidermal growth factor-like growth factor shedding enhances hypoxic cell death in H9c2 cardiomyoblasts via the activation of caspase-3 and c-Jun N-terminal kinase. J Biol Chem. 2009 May 1;284(18):12399-409. Epub 2009 Feb 4. PubMed PMID: 19193634; PubMed Central PMCID: PMC2673307. 79: Arai H, Oshiro H, Yamanaka S, Yukawa N, Wada N, Rino Y, Watanuki Y, Yamanaka S, Inayama Y, Lee J, Nakayama H, Masuda M. Grade I lymphomatoid granulomatosis with increased uptake of [18F] fluorodeoxyglucose in positron emission tomography: a case report. J Clin Exp Hematop. 2009 May;49(1):39-44. Review. PubMed PMID: 19474516. 80: Nakayama H, Kimura S. Chirally twisted oligo(phenyleneethynylene) by cyclization with alpha-helical peptide. J Org Chem. 2009 May 1;74(9):3462-8. PubMed PMID: 19351153. 81: Nibe K, Nakayama H, Uchida K. Immunohistochemical features of dystrophic axons in Papillon dogs with neuroaxonal dystrophy. Vet Pathol. 2009 May;46(3):474-83. Epub 2009 Jan 27. PubMed PMID: 19176506. 82: Yamauchi H, Katayama K, Ueno M, Kanemitsu H, Nam C, Mikami T, Saito A, Ishida Y, Uetsuka K, Doi K, Ohmach Y, Nakayama H. Etoposide induces TRP53-dependent apoptosis and TRP53-independent cell cycle arrest in trophoblasts of the developing mouse placenta. Biol Reprod. 2009 Apr;80(4):813-22. Epub 2008 Dec 23. PubMed PMID: 19109225. 83: Miwa Y, Kurosawa A, Ogawa H, Nakayama H, Sasai H, Sasaki N. Neoplasitic diseases in ferrets in Japan: a questionnaire study for 2000 to 2005. J Vet Med Sci. 2009 Apr;71(4):397-402. PubMed PMID: 19420840. 84: Nakayama H, Akiyama M, Taoka M, Yamauchi Y, Nobe Y, Ishikawa H, Takahashi N, Isobe T. Ariadne: a database search engine for identification and chemical analysis of RNA using tandem mass spectrometry data. Nucleic Acids Res. 2009 Apr;37(6):e47. Epub 2009 Mar 6. PubMed PMID: 19270066; PubMed Central PMCID: PMC2665244. 85: Ueda K, Fukase Y, Katagiri T, Ishikawa N, Irie S, Sato TA, Ito H, Nakayama H, Miyagi Y, Tsuchiya E, Kohno N, Shiwa M, Nakamura Y, Daigo Y. Targeted serum glycoproteomics for the discovery of lung cancer-associated glycosylation disorders using lectin-coupled ProteinChip arrays. Proteomics. 2009 Apr;9(8):2182-92. PubMed PMID: 19322776. 86: Wang C, Nakayama H, Sugahara S, Sakae T, Tokuuye K. Comparisons of dose-volume histograms for proton-beam versus 3-D conformal x-ray therapy in patients with stage I non-small cell lung cancer. Strahlenther Onkol. 2009 Apr;185(4):231-4. Epub 2009 Apr 16. PubMed PMID: 19370425. 87: Kawahara K, Yoshida A, Koga K, Yokoo S, Kuniyasu A, Gotoh T, Sawada M, Nakayama H. Marked induction of inducible nitric oxide synthase and tumor necrosis factor-alpha in rat CD40+ microglia by comparison to CD40- microglia. J Neuroimmunol. 2009 Mar 31;208(1-2):70-9. Epub 2009 Feb 10. PubMed PMID: 19211155. 88: Kurokawa K, Lee H, Roh KB, Asanuma M, Kim YS, Nakayama H, Shiratsuchi A, Choi Y, Takeuchi O, Kang HJ, Dohmae N, Nakanishi Y, Akira S, Sekimizu K, Lee BL. The Triacylated ATP Binding Cluster Transporter Substrate-binding Lipoprotein of Staphylococcus aureus Functions as a Native Ligand for Toll-like Receptor 2. J Biol Chem. 2009 Mar 27;284(13):8406-11. Epub 2009 Jan 12. PubMed PMID: 19139093; PubMed Central PMCID: PMC2659198. 89: Nakanishi J, Nakayama H, Shimizu T, Ishida H, Kikuchi Y, Yamaguchi K, Horiike Y. Light-regulated activation of cellular signaling by gold nanoparticles that capture and release amines. J Am Chem Soc. 2009 Mar 25;131(11):3822-3. PubMed PMID: 19256545. 90: Matsushima S, Maeda K, Inoue K, Ohta KY, Yuasa H, Kondo T, Nakayama H, Horita S, Kusuhara H, Sugiyama Y. The inhibition of human multidrug and toxin extrusion 1 is involved in the drug-drug interaction caused by cimetidine. Drug Metab Dispos. 2009 Mar;37(3):555-9. Epub 2008 Dec 12. PubMed PMID: 19074525. 91: Boiani L, Gerpe A, Arán VJ, Torres de Ortiz S, Serna E, Vera de Bilbao N, Sanabria L, Yaluff G, Nakayama H, Rojas de Arias A, Maya JD, Morello JA, Cerecetto H, González M. In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles. Eur J Med Chem. 2009 Mar;44(3):1034-40. Epub 2008 Jun 28. PubMed PMID: 18706738. 92: Oe Y, Soejima H, Nakayama H, Fukunaga T, Sugamura K, Kawano H, Sugiyama S, Matsuo K, Shinohara M, Izumi Y, Ogawa H. Significant association between score of periodontal disease and coronary artery disease. Heart Vessels. 2009 Mar;24(2):103-7. Epub 2009 Apr 1. PubMed PMID: 19337793. 93: Kanemitsu H, Yamauchi H, Komatsu M, Yamamoto S, Okazaki S, Nakayama H. Time-course changes in neural cell apoptosis in the rat fetal brain from dams treated with 6-mercaptopurine (6-MP). Histol Histopathol. 2009 Mar;24(3):317-24. PubMed PMID: 19130401. 94: Ano Y, Nakayama H, Sakudo A, Sawano Y, Tanokura M, Itohara S, Onodera T. Intestinal uptake of amyloid beta protein through columnar epithelial cells in suckling mice. Histol Histopathol. 2009 Mar;24(3):283-92. PubMed PMID: 19130397. 95: Kawase T, Okuda K, Kogami H, Nakayama H, Nagata M, Nakata K, Yoshie H. Characterization of human cultured periosteal sheets expressing bone-forming potential: in vitro and in vivo animal studies. J Tissue Eng Regen Med. 2009 Mar;3(3):218-29. PubMed PMID: 19266490. 96: Kanemitsu H, Yamauchi H, Komatsu M, Yamamoto S, Okazaki S, Uchida K, Nakayama H. 6-Mercaptopurine (6-MP) induces cell cycle arrest and apoptosis of neural progenitor cells in the developing fetal rat brain. Neurotoxicol Teratol. 2009 Mar-Apr;31(2):104-9. Epub 2008 Oct 15. PubMed PMID: 18951973. 97: Makise M, Takehara M, Kuniyasu A, Matsui N, Nakayama H, Mizushima T. Linkage between phosphorylation of the origin recognition complex and its ATP binding activity in Saccharomyces cerevisiae. J Biol Chem. 2009 Feb 6;284(6):3396-407. Epub 2008 Dec 8. PubMed PMID: 19068484. 98: Hata M, Tokuuye K, Shioyama Y, Nomoto S, Inadome Y, Fukumitsu N, Nakayama H, Sugahara S, Ohara K, Noguchi M, Akine Y. Malignant myoepithelioma in the maxillary sinus: case report and review of the literature. Anticancer Res. 2009 Feb;29(2):497-501. PubMed PMID: 19331194. 99: Ishihara S, Nakayama H, Izumi H, Nagase D, Fujimoto Y, Natori K, Ando T, Shibuya K, Makimura K, Sakai F, Kuraishi Y. [The 1st Kantou Symposium on Respiratory Mycosis: Autopsy case of invasive mucormycoses manifested as breakthrough infection]. Jpn J Antibiot. 2009 Feb;62(1):53-68. Japanese. PubMed PMID: 19378768. 100: Nakayama H, Echizen H, Gomi T, Shibuya Y, Nakamura Y, Nakano K, Arashi H, Itai T, Ohnishi S, Tanaka M, Orii T. Urinary lipocalin-type prostaglandin D synthase: a potential marker for early gentamicin-induced renal damage? Ther Drug Monit. 2009 Feb;31(1):126-30. PubMed PMID: 19125150. 101: Kagohashi K, Nakayama H, Kagei K, Kurishima K, Ishikawa H, Satoh H. Thoracic radiotherapy for mediastinal nodal recurrence. Acta Medica (Hradec Kralove). 2009;52(1):23-5. PubMed PMID: 19754004. 102: Saito H, Yamada K, Hamanaka N, Oshita F, Ito H, Nakayama H, Yokose T, Kameda Y, Noda K. Initial findings and progression of lung adenocarcinoma on serial computed tomography scans. J Comput Assist Tomogr. 2009 Jan-Feb;33(1):42-8. PubMed PMID: 19188783. 103: Tadokoro M, Tsumeda S, Tsuhara N, Nakayama H, Miyazato Y, Tamamitsu K, Vinu A, Ariga K. Electric double-layer capacitance of carbon nanocages. J Nanosci Nanotechnol. 2009 Jan;9(1):391-5. PubMed PMID: 19441324. 104: Nakayama H, Akasaka H, Tsuhako M. Complete protection of sodium valproate from humidity by using a hydrotalcite composite. J Pharm Sci. 2009 Jan;98(1):46-9. PubMed PMID: 18425808. 105: He XJ, Uchida K, Tochitani T, Uetsuka K, Miwa Y, Nakayama H. Spontaneous cutaneous mast cell tumor with lymph node metastasis in a Richardson's ground squirrel (Spermophilus richardsonii). J Vet Diagn Invest. 2009 Jan;21(1):156-9. PubMed PMID: 19139521. 106: Matsui T, Komiya A, Shimada K, Nakayama H, Tohma S. Neutrophil CD64 as a marker of infection in patients treated with tocilizumab. Mod Rheumatol. 2009;19(6):696-7. PubMed PMID: 19728012. 107: Shimada K, Matsui T, Kawakami M, Hayakawa H, Futami H, Michishita K, Takaoka H, Ikenaka T, Komiya A, Nakayama H, Hagiwara F, Sugii S, Furukawa H, Ozawa Y, Tohma S. Diffuse chronic leptomeningitis with seropositive rheumatoid arthritis: report of a case successfully treated as rheumatoid leptomeningitis. Mod Rheumatol. 2009;19(5):556-62. Epub 2009 Jun 12. PubMed PMID: 19521743. 108: Shinozaki M, Okubo Y, Nakayama H, Mitsuda A, Ide T, Yamagata Murayama S, Shibuya K. Application of in situ hybridization to tissue sections for identification of molds causing invasive fungal infection. Nippon Ishinkin Gakkai Zasshi. 2009;50(2):75-83. Review. PubMed PMID: 19430181. 109: Ano Y, Sakudo A, Nakayama H, Onodera T. Uptake and dynamics of infectious prion protein in the intestine. Protein Pept Lett. 2009;16(3):247-55. Review. PubMed PMID: 19275737. 110: Yoshida N, Nakayama H, Hemmi A, Suzuki T, Takayama T. Duodenal stenosis caused by cystic dystrophy in heterotopic pancreas: report of a case. Surg Today. 2009;39(9):803-6. Epub 2009 Sep 24. PubMed PMID: 19779779. 111: Kumagai K, Ito K, Ando Y, Hakamata S, Teranishi M, Nakayama H, Manabe S. Neutralization of IL-10 exacerbates cycloheximide-induced hepatocellular apoptosis and necrosis. Toxicol Pathol. 2009;37(4):536-46. Epub 2009 Apr 24. PubMed PMID: 19395591. 112: Nakayama H, Hamada M, Fujikake N, Nagai Y, Zhao J, Hatano O, Shimoke K, Isosaki M, Yoshizumi M, Ikeuchi T. ER stress is the initial response to polyglutamine toxicity in PC12 cells. Biochem Biophys Res Commun. 2008 Dec 12;377(2):550-5. Epub 2008 Oct 12. PubMed PMID: 18854177. 113: Maeda H, Chiba T, Tsuhako M, Nakayama H. Phosphorylation of nucleosides and nucleotides with inorganic monoimido-cyclo-triphosphate. Chem Pharm Bull (Tokyo). 2008 Dec;56(12):1698-703. PubMed PMID: 19043242. 114: Okubo Y, Nakayama H, Hasegawa C, Mitsuda A, Hatori T, Tanikawa K, Shinozaki M, Shibuya K. [Pathophysiology of invasive fungal infection in diabetic patients]. Nippon Rinsho. 2008 Dec;66(12):2327-33. Review. Japanese. PubMed PMID: 19069100. 115: Kikuchi Y, Nakanishi J, Shimizu T, Nakayama H, Inoue S, Yamaguchi K, Iwai H, Yoshida Y, Horiike Y, Takarada T, Maeda M. Arraying heterotypic single cells on photoactivatable cell-culturing substrates. Langmuir. 2008 Nov 18;24(22):13084-95. Epub 2008 Oct 17. PubMed PMID: 18925763. 116: Jaleel N, Nakayama H, Chen X, Kubo H, MacDonnell S, Zhang H, Berretta R, Robbins J, Cribbs L, Molkentin JD, Houser SR. Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes. Circ Res. 2008 Nov 7;103(10):1109-19. Epub 2008 Oct 2. PubMed PMID: 18832749; PubMed Central PMCID: PMC2678411. 117: Oshiro Y, Sugahara S, Noma M, Sato M, Sakakibara Y, Sakae T, Hayashi Y, Nakayama H, Tsuboi K, Fukumitsu N, Kanemoto A, Hashimoto T, Tokuuye K. Proton beam therapy interference with implanted cardiac pacemakers. Int J Radiat Oncol Biol Phys. 2008 Nov 1;72(3):723-7. Epub 2008 Jun 4. PubMed PMID: 18538490. 118: Shimizu F, Sano Y, Maeda T, Abe MA, Nakayama H, Takahashi R, Ueda M, Ohtsuki S, Terasaki T, Obinata M, Kanda T. Peripheral nerve pericytes originating from the blood-nerve barrier expresses tight junctional molecules and transporters as barrier-forming cells. J Cell Physiol. 2008 Nov;217(2):388-99. PubMed PMID: 18543246. 119: Izumi M, Ohara K, Hoashi T, Nakayama H, Chiu CS, Nagai T, Matsubayashi J, Iwaya K, Mukai K. Subungual melanoma: histological examination of 50 cases from early stage to bone invasion. J Dermatol. 2008 Nov;35(11):695-703. PubMed PMID: 19120763. 120: Shimizu E, Kawahara K, Kajizono M, Sawada M, Nakayama H. IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia. J Immunol. 2008 Nov 1;181(9):6503-13. PubMed PMID: 18941241. 121: Tanaka M, Kato N, Nakayama H, Nakatani M, Takahata Y. Expression of class I knotted1-like homeobox genes in the storage roots of sweetpotato (Ipomoea batatas). J Plant Physiol. 2008 Nov 1;165(16):1726-35. Epub 2008 Feb 19. PubMed PMID: 18242774. 122: Hisaki H, Okazaki T, Kubota M, Nakane M, Fujimaki T, Nakayama H, Nakagomi T, Tamura A, Masuda H. L-PDMP improves glucosylceramide synthesis and behavior in rats with focal ischemia. Neurol Res. 2008 Nov;30(9):979-84. Epub 2008 Aug 7. PubMed PMID: 18691449. 123: He XJ, Uetsuka K, Nakayama H. Neural progenitor cells are protected against MPTP by MAO-B inhibitors. Neurotoxicology. 2008 Nov;29(6):1141-6. Epub 2008 Jun 18. PubMed PMID: 18606181. 124: Yokoyama A, Dairaku N, Kusano M, Koshita S, Shimada N, Yamagiwa T, Kojima Y, Ojima T, Ikeya S, Nakayama H, Sugai Y, Hiwatashi N, Asano S. [Two cases of primary unresectable and/or recurrent gastrointestinal stromal tumors of small intestine presenting hemoperitoneum caused by administration of imatinib mesylate]. Nippon Shokakibyo Gakkai Zasshi. 2008 Nov;105(11):1619-26. Review. Japanese. PubMed PMID: 18987447. 125: Nakayama H. [Seeking "Etwas Neues"--from bioorganic chemistry to Alzheimer's disease]. Yakugaku Zasshi. 2008 Nov;128(11):1631-43. Review. Japanese. PubMed PMID: 18981699. 126: Sasai T, Hirano Y, Maeda S, Matsunaga I, Otsuka A, Morita D, Nishida R, Nakayama H, Kuwahara Y, Sugita M, Mori N. Induction of allergic contact dermatitis by astigmatid mite-derived monoterpene, alpha-acaridial. Biochem Biophys Res Commun. 2008 Oct 24;375(3):336-40. Epub 2008 Aug 9. PubMed PMID: 18694730. 127: Shimohata T, Ozawa T, Nakayama H, Tomita M, Shinoda H, Nishizawa M. Frequency of nocturnal sudden death in patients with multiple system atrophy. J Neurol. 2008 Oct;255(10):1483-5. Epub 2008 Jul 28. PubMed PMID: 18670800. 128: Isobe K, Matsunaga S, Nakayama H, Uetsuka K. Hepatic lesions of a standard poodle dog with intrahepatic portosystemic shunt. J Vet Med Sci. 2008 Oct;70(10):1125-8. PubMed PMID: 18981673. 129: Takeuchi Y, Matsuura S, Fujino Y, Nakajima M, Takahashi M, Nakashima K, Sakai Y, Uetsuka K, Ohno K, Nakayama H, Tsujimoto H. Hypereosinophilic syndrome in two cats. J Vet Med Sci. 2008 Oct;70(10):1085-9. PubMed PMID: 18981665. 130: Dehari R, Nakamura Y, Okamoto N, Nakayama H. Increased nuclear expression of growth hormone receptor in uterine cervical neoplasms of women under 40 years old. Tohoku J Exp Med. 2008 Oct;216(2):165-72. PubMed PMID: 18832799. 131: Roldos V, Nakayama H, Rolón M, Montero-Torres A, Trucco F, Torres S, Vega C, Marrero-Ponce Y, Heguaburu V, Yaluff G, Gómez-Barrio A, Sanabria L, Ferreira ME, Rojas de Arias A, Pandolfi E. Activity of a hydroxybibenzyl bryophyte constituent against Leishmania spp. and Trypanosoma cruzi: in silico, in vitro and in vivo activity studies. Eur J Med Chem. 2008 Sep;43(9):1797-807. Epub 2007 Nov 19. PubMed PMID: 18192088. 132: Li Y, Nakayama H, Notani T, Ahmad M, Tabata MJ, Takano Y. Phosphatase actions at the site of appositional mineralization in bisphosphonate-affected bones of the rat. J Med Dent Sci. 2008 Sep;55(3-4):255-65. PubMed PMID: 19697513. 133: Nakata M, Miwa Y, Nakayama H, Sakai T, Sasaki N. Localised radiotherapy for a ferret with possible anal sac apocrine adenocarcinoma. J Small Anim Pract. 2008 Sep;49(9):476-8. Epub 2008 Jul 8. PubMed PMID: 18631226. 134: Babazono A, Kitajima H, Nishimaki S, Nakamura T, Shiga S, Hayakawa M, Tanaka T, Sato K, Nakayama H, Ibara S, Une H, Doi H. Risk factors for nosocomial infection in the neonatal intensive care unit by the Japanese Nosocomial Infection Surveillance (JANIS). Acta Med Okayama. 2008 Aug;62(4):261-8. PubMed PMID: 18766209. 135: Niwa T, Yoshida T, Doiuchi T, Ito K, Nakayama H, Odagiri K, Inoue T. Factors predicting tumour regression in locally advanced cervical adenocarcinoma treated with balloon-occluded intra-arterial chemotherapy. Br J Radiol. 2008 Aug;81(968):659-65. PubMed PMID: 18628334. 136: Higuchi K, Santiwong P, Tamaki H, Terashima T, Nakayama H, Notani T, Iseki H, Baba O, Takano Y. Development and terminal differentiation of pulp and periodontal nerve elements in subcutaneous transplants of molar tooth germs and incisors of the rat. Eur J Oral Sci. 2008 Aug;116(4):324-33. PubMed PMID: 18705800. 137: Saito A, Yamauchi H, Ishida Y, Ohmachi Y, Nakayama H. Defect of the cerebellar vermis induced by prenatal gamma-ray irradiation in radiosensitive BALB/c mice. Histol Histopathol. 2008 Aug;23(8):953-64. PubMed PMID: 18498070. 138: Sasaya H, Utsumi T, Shimoke K, Nakayama H, Matsumura Y, Fukunaga K, Ikeuchi T. Nicotine suppresses tunicamycin-induced, but not thapsigargin-induced, expression of GRP78 during ER stress-mediated apoptosis in PC12 cells. J Biochem. 2008 Aug;144(2):251-7. Epub 2008 May 13. PubMed PMID: 18477628. 139: Yamato O, Hayashi D, Satoh H, Shoda T, Uchida K, Nakayama H, Sakai H, Masegi T, Murai A, Iida T, Hisada H, Hisada A, Yamasaki M, Maede Y, Arai T. Retrospective diagnosis of feline GM2 gangliosidosis variant 0 (Sandhoff-like disease) in Japan: possible spread of the mutant allele in the Japanese domestic cat population. J Vet Med Sci. 2008 Aug;70(8):813-8. PubMed PMID: 18772556. 140: Ano Y, Nakayama H, Sakai Y, Sakudo A, Endo M, Ebisu S, Li J, Uetsuka K, Manabe N, Onodera T. Incorporation of beta-amyloid protein through the bovine ileal epithelium before and after weaning: model for orally transmitted amyloidoses. Microbiol Immunol. 2008 Aug;52(8):429-34. PubMed PMID: 18667042. 141: Shibasaki H, Nakayama H, Furuta T, Kasuya Y, Tsuchiya M, Soejima A, Yamada A, Nagasawa T. Simultaneous determination of prednisolone, prednisone, cortisol, and cortisone in plasma by GC-MS: estimating unbound prednisolone concentration in patients with nephrotic syndrome during oral prednisolone therapy. J Chromatogr B Analyt Technol Biomed Life Sci. 2008 Jul 15;870(2):164-9. Epub 2008 Mar 8. PubMed PMID: 18387858. 142: Shoji R, Nakayama H, Sakai Y, Mohri S, Yamada M. Evaluation of the ecotoxicity of solid wastes using rapid leaching test and bioassays. J Environ Sci Health A Tox Hazard Subst Environ Eng. 2008 Jul 15;43(9):1048-53. PubMed PMID: 18569319. 143: Oshiro H, Miyagi Y, Kawaguchi Y, Rino Y, Arai H, Asai-Sato M, Nakayama H, Yamanaka S, Inayama Y, Fukushima N. Endometrial adenocarcinoma without myometrial invasion metastasizing to the pancreas and masquerading as primary pancreatic neoplasm. Pathol Int. 2008 Jul;58(7):456-61. PubMed PMID: 18577117. 144: Takeuchi Y, Uetsuka K, Murayama M, Kikuta F, Takashima A, Doi K, Nakayama H. Complementary distributions of amyloid-beta and neprilysin in the brains of dogs and cats. Vet Pathol. 2008 Jul;45(4):455-66. PubMed PMID: 18587091. 145: Kobori M, Nakayama H, Fukushima K, Ohnishi-Kameyama M, Ono H, Fukushima T, Akimoto Y, Masumoto S, Yukizaki C, Hoshi Y, Deguchi T, Yoshida M. Bitter gourd suppresses lipopolysaccharide-induced inflammatory responses. J Agric Food Chem. 2008 Jun 11;56(11):4004-11. Epub 2008 May 20. PubMed PMID: 18489106. 146: Mizumoto M, Tokuuye K, Sugahara S, Nakayama H, Fukumitsu N, Ohara K, Abei M, Shoda J, Tohno E, Minami M. Proton beam therapy for hepatocellular carcinoma adjacent to the porta hepatis. Int J Radiat Oncol Biol Phys. 2008 Jun 1;71(2):462-7. Epub 2008 Feb 19. PubMed PMID: 18243571. 147: Isobe K, Nakayama H, Uetsuka K. Relation between lipogranuloma formation and fibrosis, and the origin of brown pigments in lipogranuloma of the canine liver. Comp Hepatol. 2008 May 12;7:5. PubMed PMID: 18471325; PubMed Central PMCID: PMC2391139. 148: Wada N, Masudo K, Nakayama H, Suganuma N, Matsuzu K, Hirakawa S, Rino Y, Masuda M, Imada T. Recommendation for subclass evaluation of TNM stage iva papillary thyroid carcinomas: T4aN1b patients are at risk for recurrence and survival. Ann Surg Oncol. 2008 May;15(5):1511-7. Epub 2008 Feb 26. PubMed PMID: 18299932. 149: Iwabuchi K, Prinetti A, Sonnino S, Mauri L, Kobayashi T, Ishii K, Kaga N, Murayama K, Kurihara H, Nakayama H, Yoshizaki F, Takamori K, Ogawa H, Nagaoka I. Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils. Glycoconj J. 2008 May;25(4):357-74. Epub 2007 Nov 28. Erratum in: Glycoconj J. 2008 May;25(4):355-6. PubMed PMID: 18041581. 150: Taniai H, Iida K, Seki M, Saito M, Shiota S, Nakayama H, Yoshida S. Concerted action of lactate oxidase and pyruvate oxidase in aerobic growth of Streptococcus pneumoniae: role of lactate as an energy source. J Bacteriol. 2008 May;190(10):3572-9. Epub 2008 Mar 14. PubMed PMID: 18344365; PubMed Central PMCID: PMC2395018. 151: Woo GH, Bak EJ, Lee YW, Nakayama H, Sasaki N, Doi K. Cervical chondroid chordoma in a Shetland sheep dog. J Comp Pathol. 2008 May;138(4):218-23. PubMed PMID: 18374350. 152: Ikehara M, Saito H, Yamada K, Oshita F, Noda K, Nakayama H, Masui K, Kameda Y, Komase Y, Miyazawa T. Prognosis of small adenocarcinoma of the lung based on thin-section computed tomography and pathological preparations. J Comput Assist Tomogr. 2008 May-Jun;32(3):426-31. PubMed PMID: 18520551. 153: Takeuchi Y, Ohnishi Y, Matsunaga S, Nakayama H, Uetsuka K. Intracranial meningioma with polygonal granular cell appearance in a Chihuahua. J Vet Med Sci. 2008 May;70(5):529-32. PubMed PMID: 18525181. 154: Nakayama H, Mizowaki T, Narita Y, Kawada N, Takahashi K, Mihara K, Hiraoka M. Development of a three-dimensionally movable phantom system for dosimetric verifications. Med Phys. 2008 May;35(5):1643-50. PubMed PMID: 18561639. 155: He XJ, Yamauchi H, Uetsuka K, Nakayama H. Neurotoxicity of MPTP to migrating neuroblasts: studies in acute and subacute mouse models of Parkinson's disease. Neurotoxicology. 2008 May;29(3):413-20. Epub 2008 Feb 23. PubMed PMID: 18387672. 156: Nishimura S, Takahashi S, Kamikatahira H, Kuroki Y, Jaalouk DE, O'Brien S, Koivunen E, Arap W, Pasqualini R, Nakayama H, Kuniyasu A. Combinatorial targeting of the macropinocytotic pathway in leukemia and lymphoma cells. J Biol Chem. 2008 Apr 25;283(17):11752-62. Epub 2008 Feb 21. PubMed PMID: 18292083. 157: Kaneko K, Akuta T, Sawa T, Kim HW, Fujii S, Okamoto T, Nakayama H, Ohigashi H, Murakami A, Akaike T. Mutagenicity of 8-nitroguanosine, a product of nitrative nucleoside modification by reactive nitrogen oxides, in mammalian cells. Cancer Lett. 2008 Apr 18;262(2):239-47. Epub 2008 Jan 11. PubMed PMID: 18248787. 158: Kodama M, Kitadai Y, Shishido T, Shimamoto M, Fukumoto A, Masuda H, Tanaka S, Yoshihara M, Sakai A, Nakayama H, Chayama K. Primary follicular lymphoma of the gastrointestinal tract: a retrospective case series. Endoscopy. 2008 Apr;40(4):343-6. Epub 2007 Dec 7. PubMed PMID: 18067068. 159: Nakayama H, Itoh H, Kunita S, Kuroda N, Hiroi M, Matsuura H, Yasui W, Enzan H. Presence of perivenular elastic fibers in nonalcoholic steatohepatitis Fibrosis Stage III. Histol Histopathol. 2008 Apr;23(4):407-9. PubMed PMID: 18228197. 160: Matsui O, Fujita K, Nakayama H, Taniguchi M, Tarui Y, Hirasawa E, Usuki Y, Tanaka T. Isolation of an Acremonium sp. capable of liquefying cross-linked poly(gamma-glutamic acid) hydrogels and the fungal enzyme involved in the disruption of gamma-ray irradiation-mediated cross-linking. J Biosci Bioeng. 2008 Apr;105(4):422-4. PubMed PMID: 18499062. 161: Seki M, Saito M, Iida K, Taniai H, Soejima T, Nakayama H, Yoshida S. Onset of streptococcal toxic shock syndrome is accelerated by bruising in a mouse model. Microb Pathog. 2008 Apr;44(4):339-43. Epub 2007 Oct 30. PubMed PMID: 18061395. 162: Tomiyama A, Nakayama H, Aoki K, Ueda M. Solitary metastasis of renal cell carcinoma to the third ventricular choroid plexus with rapid clinical manifestation by intratumoral hemorrhage. Neurol India. 2008 Apr-Jun;56(2):179-81. PubMed PMID: 18688144. 163: Oide T, Nakayama H, Yanagawa S, Ito N, Ikeda S, Arima K. Extensive loss of arterial medial smooth muscle cells and mural extracellular matrix in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL). Neuropathology. 2008 Apr;28(2):132-42. Epub 2007 Nov 6. PubMed PMID: 18021191. 164: Hirayama C, Watanabe H, Nakashima R, Nanbu T, Hamada A, Kuniyasu A, Nakayama H, Kawaguchi T, Saito H. Constitutive overexpression of P-glycoprotein, rather than breast cancer resistance protein or organic cation transporter 1, contributes to acquisition of imatinib-resistance in K562 cells. Pharm Res. 2008 Apr;25(4):827-35. Epub 2007 Oct 13. PubMed PMID: 17934801. 165: Shimohata T, Ozawa T, Nakayama H, Tomita M, Nishizawa M. Tracheostomy can fatally exacerbate sleep-disordered breathing in multiple system atrophy. Neurology. 2008 Mar 18;70(12):980-1; author reply 981-2. PubMed PMID: 18354815. 166: Yoshizaki F, Nakayama H, Iwahara C, Takamori K, Ogawa H, Iwabuchi K. Role of glycosphingolipid-enriched microdomains in innate immunity: microdomain-dependent phagocytic cell functions. Biochim Biophys Acta. 2008 Mar;1780(3):383-92. Epub 2007 Nov 22. Review. PubMed PMID: 18078821. 167: Ogino H, Nakayama H, China H, Kawata T, Doukyu N, Yasuda M. Characterization of recombinant glyoxylate reductase from thermophile Thermus thermophilus HB27. Biotechnol Prog. 2008 Mar-Apr;24(2):321-5. Epub 2008 Feb 27. PubMed PMID: 18302405. 168: Nakayama H, Yoshizaki F, Prinetti A, Sonnino S, Mauri L, Takamori K, Ogawa H, Iwabuchi K. Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. J Leukoc Biol. 2008 Mar;83(3):728-41. Epub 2007 Nov 30. PubMed PMID: 18055569. 169: Okabayashi S, Ohno C, Kato M, Nakayama H, Yasutomi Y. Congenital cystic adenomatoid-like malformation in a cynomolgus monkey (Macaca fascicularis). Vet Pathol. 2008 Mar;45(2):232-5. PubMed PMID: 18424840. 170: Hashizume T, Yamada K, Okamoto N, Saito H, Oshita F, Kato Y, Ito H, Nakayama H, Kameda Y, Noda K. Prognostic significance of thin-section CT scan findings in small-sized lung adenocarcinoma. Chest. 2008 Feb;133(2):441-7. Epub 2007 Dec 10. PubMed PMID: 18071015. 171: Wada N, Masudo K, Nakayama H, Suganuma N, Matsuzu K, Hirakawa S, Rino Y, Masuda M, Imada T. Clinical outcomes in older or younger patients with papillary thyroid carcinoma: impact of lymphadenopathy and patient age. Eur J Surg Oncol. 2008 Feb;34(2):202-7. Epub 2007 Nov 19. PubMed PMID: 18023321. 172: Isobe K, Matsunaga S, Nakayama H, Uetsuka K. Histopathological characteristics of hepatic lipogranulomas with portosystemic shunt in dogs. J Vet Med Sci. 2008 Feb;70(2):133-8. PubMed PMID: 18319572. 173: Nakayama H, Echizen H, Tanaka M, Sato M, Orii T. Reduced vancomycin clearance despite unchanged creatinine clearance in patients treated with vancomycin for longer than 4 weeks. Ther Drug Monit. 2008 Feb;30(1):103-7. PubMed PMID: 18223471. 174: Setoguchi K, Ishida H, Shimmura H, Shimizu T, Shirakawa H, Omoto K, Toki D, Iida S, Setoguchi S, Tokumoto T, Horita S, Nakayama H, Yamaguchi Y, Tanabe K. Analysis of renal transplant protocol biopsies in ABO-incompatible kidney transplantation. Am J Transplant. 2008 Jan;8(1):86-94. Epub 2007 Nov 12. PubMed PMID: 18021283. 175: Wada N, Yoshida A, Miyagi Y, Yamamoto T, Nakayama H, Suganuma N, Matsuzu K, Masudo K, Hirakawa S, Rino Y, Masuda M, Imada T. Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature. Anticancer Res. 2008 Jan-Feb;28(1A):139-44. PubMed PMID: 18383837. 176: Iida M, Tsujimoto S, Nakayama H, Yagishita S. Ultrastructural study of neuronal and related tumors in the ventricles. Brain Tumor Pathol. 2008;25(1):19-23. Epub 2008 Apr 16. PubMed PMID: 18415662. 177: Kaneko K, Fukuda H, Chuang VT, Yamasaki K, Kawahara K, Nakayama H, Suenaga A, Maruyama T, Otagiri M. Subdomain IIIA of dog albumin contains a binding site similar to site II of human albumin. Drug Metab Dispos. 2008 Jan;36(1):81-6. Epub 2007 Oct 9. PubMed PMID: 17925384. 178: Kiyota A, Tsukimori K, Yumoto Y, Hojo S, Morokuma S, Fukushima K, Takahata Y, Nakayama H, Wake N. Spontaneous resolution of cystic hygroma and hydrops in a fetus with Noonan's syndrome. Fetal Diagn Ther. 2008;24(4):499-502. Epub 2009 Jan 17. PubMed PMID: 19151555. 179: Ochiai M, Hikino S, Yabuuchi H, Nakayama H, Sato K, Ohga S, Hara T. A new scoring system for computed tomography of the chest for assessing the clinical status of bronchopulmonary dysplasia. J Pediatr. 2008 Jan;152(1):90-5, 95.e1-3. Epub 2007 Oct 22. PubMed PMID: 18154907. 180: Ochiai M, Nakayama H, Sato K, Iida K, Hikino S, Ohga S, Tsukimori K, Wake N, Masumoto K, Taguchi T, Hara T. Head circumference and long-term outcome in small-for-gestational age infants. J Perinat Med. 2008;36(4):341-7. PubMed PMID: 18598125. 181: Cho T, Aoyama T, Toyoda M, Nakayama H, Chibana H, Kaminishi H, Calderone RA. [Farnesol as a quorum-sensing molecule in Candida albicans]. Nippon Ishinkin Gakkai Zasshi. 2008;49(4):281-6. Review. Japanese. PubMed PMID: 19001754. 182: Nakayama H, Aoyama T. [Molecular biology for medical mycology]. Nippon Ishinkin Gakkai Zasshi. 2008;49(2):131-6. Review. Japanese. PubMed PMID: 18451595. 183: Sakurabayashi T, Kikuchi H, Nakayama H, Osawa Y, Shimada H, Miyazaki S, Yuasa Y, Sakai S, Suzuki M, Takahashi S, Hirasawa Y. [Changes in the prognosis for survival of patients with end-stage renal disease (ESRD) treated by hemodialysis]. Nippon Jinzo Gakkai Shi. 2008;50(2):127-34. Japanese. PubMed PMID: 18421969. 184: Nakayama H, Ichinose S, Kato Y, Ito H, Masui K, Kameda Y. Long-term survival after a surgical resection of pulmonary metastases from gastric cancer: report of a case. Surg Today. 2008;38(2):150-3. Epub 2008 Feb 1. Review. PubMed PMID: 18239874. 185: Nishikawa S, Doi K, Nakayama H, Uetsuka K. The effect of fasting on hepatic lipid accumulation and transcriptional regulation of lipid metabolism differs between C57BL/6J and BALB/cA mice fed a high-fat diet. Toxicol Pathol. 2008;36(6):850-7. Epub 2008 Sep 23. PubMed PMID: 18812581. 186: Makino T, Ishikawa K, Igarashi I, Yamoto T, Manabe S, Nakayama H. Relationship between GST Yp induction and hepatocyte proliferation in rats treated with phase II drug metabolizing enzyme inducers. Toxicol Pathol. 2008;36(3):420-7. Epub 2008 Apr 25. PubMed PMID: 18441256. 187: Nakaki S, Hino D, Miyoshi M, Nakayama H, Moriyoshi H, Morikawa T, Itohara K. Study of animal species (human, dog and cat) identification using a multiplex single-base primer extension reaction in the cytochrome b gene. Forensic Sci Int. 2007 Dec 20;173(2-3):97-102. Epub 2007 Mar 26. PubMed PMID: 17382503. 188: Ishikawa N, Takano A, Yasui W, Inai K, Nishimura H, Ito H, Miyagi Y, Nakayama H, Fujita M, Hosokawa M, Tsuchiya E, Kohno N, Nakamura Y, Daigo Y. Cancer-testis antigen lymphocyte antigen 6 complex locus K is a serologic biomarker and a therapeutic target for lung and esophageal carcinomas. Cancer Res. 2007 Dec 15;67(24):11601-11. PubMed PMID: 18089789. 189: Nakayama H, Kitaichi K, Ito Y, Hashimoto K, Takagi K, Yokoi T, Takagi K, Ozaki N, Yamamoto T, Hasegawa T. The role of organic cation transporter-3 in methamphetamine disposition and its behavioral response in rats. Brain Res. 2007 Dec 12;1184:260-9. Epub 2007 Oct 6. PubMed PMID: 17988657. 190: Otabe S, Nakayama H, Fukutani T, Yuan X, Wada N, Hashinaga T, Kato T, Inada C, Yamada K. Clinical and genetic features of childhood-onset Type 2 diabetes in Japan. Acta Diabetol. 2007 Dec;44(4):181-5. Epub 2007 Aug 31. PubMed PMID: 17763998. 191: He XJ, Yamauchi H, Suzuki K, Ueno M, Nakayama H, Doi K. Gene expression profiles of drug-metabolizing enzymes (DMEs) in rat liver during pregnancy and lactation. Exp Mol Pathol. 2007 Dec;83(3):428-34. Epub 2006 Jul 7. PubMed PMID: 16824515. 192: Nakayama H, Tanabe K, Bard M, Hodgson W, Wu S, Takemori D, Aoyama T, Kumaraswami NS, Metzler L, Takano Y, Chibana H, Niimi M. The Candida glabrata putative sterol transporter gene CgAUS1 protects cells against azoles in the presence of serum. J Antimicrob Chemother. 2007 Dec;60(6):1264-72. Epub 2007 Oct 2. PubMed PMID: 17913716. 193: Kudo K, Kojima S, Tabuchi K, Yabe H, Tawa A, Imaizumi M, Hanada R, Hamamoto K, Kobayashi R, Morimoto A, Nakayama H, Tsuchida M, Horibe K, Kigasawa H, Tsukimoto I; Japanese Childhood AML Cooperative Study Group. Prospective study of a pirarubicin, intermediate-dose cytarabine, and etoposide regimen in children with Down syndrome and acute myeloid leukemia: the Japanese Childhood AML Cooperative Study Group. J Clin Oncol. 2007 Dec 1;25(34):5442-7. PubMed PMID: 18048827. 194: Kumagai K, Kiyosawa N, Ito K, Yamoto T, Teranishi M, Nakayama H, Manabe S. Influence of Kupffer cell inactivation on cycloheximide-induced hepatic injury. Toxicology. 2007 Nov 30;241(3):106-18. Epub 2007 Aug 25. PubMed PMID: 17900782. 195: Nakayama H. [Diagnosis, clinical feature and treatment of glucocorticoid-induced osteoporosis in patients with rheumatoid arthritis]. Nippon Rinsho. 2007 Nov 28;65 Suppl 9:499-503. Review. Japanese. PubMed PMID: 18161156. 196: Nakayama H, Yamada K, Saito H, Oshita F, Ito H, Kameda Y, Noda K. Sublobar resection for patients with peripheral small adenocarcinomas of the lung: surgical outcome is associated with features on computed tomographic imaging. Ann Thorac Surg. 2007 Nov;84(5):1675-9. PubMed PMID: 17954084. 197: Shirai M, Yamauchi H, Nakayama H, Doi K, Uetsuka K. Expression of epidermal growth factor receptor protein in the liver of db/db mice after partial hepatectomy. Exp Toxicol Pathol. 2007 Nov;59(3-4):157-62. Epub 2007 Sep 7. PubMed PMID: 17826083. 198: Hata M, Tokuuye K, Sugahara S, Tohno E, Nakayama H, Fukumitsu N, Mizumoto M, Abei M, Shoda J, Minami M, Akine Y. Proton beam therapy for aged patients with hepatocellular carcinoma. Int J Radiat Oncol Biol Phys. 2007 Nov 1;69(3):805-12. Epub 2007 May 24. PubMed PMID: 17524568. 199: Nakayama H, Hirami S, Tsuhako M. Selective adsorption of mercury ion by mercaptocarboxylic acid intercalated Mg-Al layered double hydroxide. J Colloid Interface Sci. 2007 Nov 1;315(1):177-83. Epub 2007 Jun 23. PubMed PMID: 17631306. 200: Arai H, Rino Y, Fujii K, Yamada T, Suganuma N, Yukawa N, Wada N, Nakagishi Y, Imagawa T, Yamanaka S, Nakayama H, Masuda M. [Surgical treatment for pulmonary aspergillosis with hyper immunoglobulin-E syndrome; report of a case]. Kyobu Geka. 2007 Nov;60(12):1122-5. Review. Japanese. PubMed PMID: 18018659. 201: Yamauchi H, Katayama K, Ueno M, He XJ, Mikami T, Uetsuka K, Doi K, Nakayama H. Essential role of p53 in trophoblastic apoptosis induced in the developing rodent placenta by treatment with a DNA-damaging agent. Apoptosis. 2007 Oct;12(10):1743-54. PubMed PMID: 17594519. 202: Nakayama H. [Osteoporosis in the patients with rheumatoid arthritis (3) : the efficacy and the selection of the osteoporosis therapeutic drug]. Clin Calcium. 2007 Oct;17(10):1607-12. Review. Japanese. PubMed PMID: 17906416. 203: Carnes CA, Janssen PM, Ruehr ML, Nakayama H, Nakayama T, Haase H, Bauer JA, Chung MK, Fearon IM, Gillinov AM, Hamlin RL, Van Wagoner DR. Atrial glutathione content, calcium current, and contractility. J Biol Chem. 2007 Sep 21;282(38):28063-73. Epub 2007 Jul 25. PubMed PMID: 17656369. 204: Ohshima Y, Iwase M, Izumizaki M, Ishiguro T, Kanamaru M, Nakayama H, Gejyo F, Homma I. Hypoxic ventilatory response during light and dark periods and the involvement of histamine H1 receptor in mice. Am J Physiol Regul Integr Comp Physiol. 2007 Sep;293(3):R1350-6. Epub 2007 Jul 11. PubMed PMID: 17626131. 205: Nakayama H, Yoshida A, Nakamura Y, Hayashi H, Miyagi Y, Wada N, Rino Y, Masuda M, Imada T. Clinical significance of BRAF (V600E) mutation and Ki-67 labeling index in papillary thyroid carcinomas. Anticancer Res. 2007 Sep-Oct;27(5B):3645-9. PubMed PMID: 17972530. 206: Nakayama H, Chen X, Baines CP, Klevitsky R, Zhang X, Zhang H, Jaleel N, Chua BH, Hewett TE, Robbins J, Houser SR, Molkentin JD. Ca2+- and mitochondrial-dependent cardiomyocyte necrosis as a primary mediator of heart failure. J Clin Invest. 2007 Sep;117(9):2431-44. PubMed PMID: 17694179; PubMed Central PMCID: PMC1937500. 207: Nozaki Y, Kusuhara H, Kondo T, Iwaki M, Shiroyanagi Y, Nakayama H, Horita S, Nakazawa H, Okano T, Sugiyama Y. Species difference in the inhibitory effect of nonsteroidal anti-inflammatory drugs on the uptake of methotrexate by human kidney slices. J Pharmacol Exp Ther. 2007 Sep;322(3):1162-70. Epub 2007 Jun 19. PubMed PMID: 17578901. 208: Sakuma Y, Matsukuma S, Yoshihara M, Nakamura Y, Nakayama H, Kameda Y, Tsuchiya E, Miyagi Y. Epidermal growth factor receptor gene mutations in atypical adenomatous hyperplasias of the lung. Mod Pathol. 2007 Sep;20(9):967-73. Epub 2007 Jul 6. PubMed PMID: 17618248. 209: Ikuta T, Furuta N, Kihara S, Okura M, Nagamine I, Nakayama H, Ishimoto Y, Kaneda Y, Tomotake M, Izaki Y, Ming X. Differences in waveforms of cerebral evoked potentials among healthy subjects, schizophrenics, manic-depressives and epileptics. J Med Invest. 2007 Aug;54(3-4):303-15. PubMed PMID: 17878680. 210: Saji H, Kurose K, Sugiura K, Miyagi E, Onose R, Kato H, Nakayama H. Endometrial aspiration cytology for diagnosis of peritoneal lesions in extrauterine malignancies. Acta Cytol. 2007 Jul-Aug;51(4):533-40. PubMed PMID: 17718117. 211: Sakuma Y, Matsukuma S, Yoshihara M, Nakamura Y, Noda K, Nakayama H, Kameda Y, Tsuchiya E, Miyagi Y. Distinctive evaluation of nonmucinous and mucinous subtypes of bronchioloalveolar carcinomas in EGFR and K-ras gene-mutation analyses for Japanese lung adenocarcinomas: confirmation of the correlations with histologic subtypes and gene mutations. Am J Clin Pathol. 2007 Jul;128(1):100-8. PubMed PMID: 17580276. 212: Otabe S, Yuan X, Fukutani T, Wada N, Hashinaga T, Nakayama H, Hirota N, Kojima M, Yamada K. Overexpression of human adiponectin in transgenic mice results in suppression of fat accumulation and prevention of premature death by high-calorie diet. Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E210-8. Epub 2007 Mar 27. PubMed PMID: 17389708. 213: Ueno K, Uno J, Nakayama H, Sasamoto K, Mikami Y, Chibana H. Development of a highly efficient gene targeting system induced by transient repression of YKU80 expression in Candida glabrata. Eukaryot Cell. 2007 Jul;6(7):1239-47. Epub 2007 May 18. PubMed PMID: 17513567; PubMed Central PMCID: PMC1951112. 214: Nishikawa S, Yasoshima A, Doi K, Nakayama H, Uetsuka K. Involvement of sex, strain and age factors in high fat diet-induced obesity in C57BL/6J and BALB/cA mice. Exp Anim. 2007 Jul;56(4):263-72. PubMed PMID: 17660680. 215: Hata M, Tokuuye K, Kagei K, Sugahara S, Nakayama H, Fukumitsu N, Hashimoto T, Mizumoto M, Ohara K, Akine Y. Hypofractionated high-dose proton beam therapy for stage I non-small-cell lung cancer: preliminary results of a phase I/II clinical study. Int J Radiat Oncol Biol Phys. 2007 Jul 1;68(3):786-93. Epub 2007 Mar 26. PubMed PMID: 17379439. 216: Uetsuka K, Nishikawa S, Isobe K, Nakayama H. Histopathological characteristics of Kupffer cells and ito cells in the porcine and bovine liver. J Vet Med Sci. 2007 Jul;69(7):767-70. PubMed PMID: 17675812. 217: Wada N, Suganuma N, Nakayama H, Masudo K, Rino Y, Masuda M, Imada T. Microscopic regional lymph node status in papillary thyroid carcinoma with and without lymphadenopathy and its relation to outcomes. Langenbecks Arch Surg. 2007 Jul;392(4):417-22. Epub 2007 Feb 16. PubMed PMID: 17562092. 218: Yanagida M, Nakayama H, Yoshizaki F, Fujimura T, Takamori K, Ogawa H, Iwabuchi K. Proteomic analysis of plasma membrane lipid rafts of HL-60 cells. Proteomics. 2007 Jul;7(14):2398-409. PubMed PMID: 17623299. 219: Shimohata T, Shinoda H, Nakayama H, Ozawa T, Terajima K, Yoshizawa H, Matsuzawa Y, Onodera O, Naruse S, Tanaka K, Takahashi S, Gejyo F, Nishizawa M. Daytime hypoxemia, sleep-disordered breathing, and laryngopharyngeal findings in multiple system atrophy. Arch Neurol. 2007 Jun;64(6):856-61. PubMed PMID: 17562934. 220: Ohdaira F, Nakamura K, Nakayama H, Satoh M, Ohdaira T, Nakamata M, Kohno M, Iwashima A, Onda A, Kobayashi Y, Fujimori K, Kiguchi T, Izumi S, Kobayashi T, Shinoda H, Takahashi S, Gejyo F, Yamamoto M. Demographic characteristics of 3,659 Japanese patients with obstructive sleep apnea-hypopnea syndrome diagnosed by full polysomnography: associations with apnea-hypopnea index. Sleep Breath. 2007 Jun;11(2):93-101. PubMed PMID: 17221276. 221: Nakayama G, Hibi K, Nakayama H, Kodera Y, Ito K, Akiyama S, Nakao A. A highly sensitive method for the detection of p16 methylation in the serum of colorectal cancer patients. Anticancer Res. 2007 May-Jun;27(3B):1459-63. PubMed PMID: 17595762. 222: Takayama T, Nakayama H. [Systematic subsegmentectomy of the liver]. Nippon Geka Gakkai Zasshi. 2007 May;108(3):149-52. Japanese. PubMed PMID: 17533954. 223: Tsutsumi K, Nakayama H, Sakai Y, Kojima Y, Dairaku N, Ojima T, Kusano M, Ikeya S, Sugai Y, Hiwatashi N. [Two cases of patients with hepatocellular carcinoma (HCC) that developed in cryptogenic cirrhosis suggestive of nonalcoholic steatohepatitis (NASH) as background liver disease after clinical courses of 26 years]. Nippon Shokakibyo Gakkai Zasshi. 2007 May;104(5):690-7. Japanese. PubMed PMID: 17485950. 224: Wada N, Hasegawa S, Masudo Y, Hirakawa S, Matsuzu K, Suganuma N, Nakayama H, Rino Y, Imada T. Clinical outcome by AMES risk definition in Japanese differentiated thyroid carcinoma patients. Asian J Surg. 2007 Apr;30(2):102-7. PubMed PMID: 17475578. 225: Fujimoto Y, Kitaichi K, Nakayama H, Ito Y, Takagi K, Takagi K, Hasegawa T. The pharmacokinetic properties of methamphetamine in rats with previous repeated exposure to methamphetamine: the differences between Long-Evans and Wistar rats. Exp Anim. 2007 Apr;56(2):119-29. PubMed PMID: 17460357. 226: Nakayama H, Otabe S, Ueno T, Hirota N, Yuan X, Fukutani T, Hashinaga T, Wada N, Yamada K. Transgenic mice expressing nuclear sterol regulatory element-binding protein 1c in adipose tissue exhibit liver histology similar to nonalcoholic steatohepatitis. Metabolism. 2007 Apr;56(4):470-5. PubMed PMID: 17379003. 227: Suzuki K, Tanaka J, Ogaw Y, Kasai A, Ohno Y, Sakail K, Nakayama H, Tsukada H, Gejyo F, Hanzawa K, Suzuki E. [Pulmonary thromboembolism during the Niigata Chuetsu earthquake in 2004]. Nihon Kokyuki Gakkai Zasshi. 2007 Apr;45(4):324-8. Japanese. PubMed PMID: 17491310. 228: Yamabuki T, Takano A, Hayama S, Ishikawa N, Kato T, Miyamoto M, Ito T, Ito H, Miyagi Y, Nakayama H, Fujita M, Hosokawa M, Tsuchiya E, Kohno N, Kondo S, Nakamura Y, Daigo Y. Dikkopf-1 as a novel serologic and prognostic biomarker for lung and esophageal carcinomas. Cancer Res. 2007 Mar 15;67(6):2517-25. PubMed PMID: 17363569. 229: Nakayama H, Murai M, Tono-oka M, Masuda K, Ishii K. Enhancement of Structural fluctuation in the region connecting two kinds of critical points in temperature-pressure-composition three-dimensional phase diagram: Raman studies of benzene/CO2 binary systems up to supercritical region. J Phys Chem A. 2007 Mar 1;111(8):1410-8. Epub 2007 Feb 6. PubMed PMID: 17279732. 230: Tajiri M, Maehara T, Nakayama H, Sakamoto K. Decreased invasiveness via two methods of thoracoscopic lobectomy for lung cancer, compared with open thoracotomy. Respirology. 2007 Mar;12(2):207-11. PubMed PMID: 17298452. 231: Sano Y, Shimizu F, Nakayama H, Abe M, Maeda T, Ohtsuki S, Terasaki T, Obinata M, Ueda M, Takahashi R, Kanda T. Endothelial cells constituting blood-nerve barrier have highly specialized characteristics as barrier-forming cells. Cell Struct Funct. 2007;32(2):139-47. Epub 2007 Dec 5. PubMed PMID: 18057801. 232: Akiyama S, Nakayama H, Takami H, Gotoh H, Gotoh Y. Pharmacodynamic study of the Saltz regimen for metastatic colorectal cancer in a hemodialyzed patient. Chemotherapy. 2007;53(6):418-21. Epub 2007 Oct 19. PubMed PMID: 17952001. 233: Nakayama H, Wada N, Masudo Y, Rino Y. Axillary lymph node metastasis from papillary thyroid carcinoma: report of a case. Surg Today. 2007;37(4):311-5. Epub 2007 Mar 26. PubMed PMID: 17387564.