#Uploaded_variation	Location	Allele	Consequence	IMPACT	SYMBOL	Gene	Feature_type	Feature	BIOTYPE	EXON	INTRON	HGVSc	HGVSp	cDNA_position	CDS_position	Protein_position	Amino_acids	Codons	Existing_variation	DISTANCE	STRAND	FLAGS	SYMBOL_SOURCE	HGNC_ID	MANE_SELECT	MANE_PLUS_CLINICAL	TSL	APPRIS	REFSEQ_MATCH	SOURCE	REFSEQ_OFFSET	GIVEN_REF	USED_REF	BAM_EDIT	SIFT	PolyPhen	AF	CLIN_SIG	SOMATIC	PHENO	PUBMED	MOTIF_NAME	MOTIF_POS	HIGH_INF_POS	MOTIF_SCORE_CHANGE	TRANSCRIPTION_FACTORS
.	10:48054-48054	G	start_lost	HIGH	TUBB8	347688	Transcript	XM_017016193.3	protein_coding	2/2	-	-	-	95	2	1	M/T	aTg/aCg	rs61839058,COSV59114659	-	-1	-	EntrezGene	HGNC:20773	-	-	-	-	-	RefSeq	-	A	A	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:1096268-1096268	C	stop_lost	HIGH	WDR37	ENSG00000047056	Transcript	ENST00000381329.5	protein_coding	9/9	-	-	-	949	748	250	*/R	Tga/Cga	rs10794716	-	1	-	HGNC	HGNC:31406	-	-	1	-	-	Ensembl	-	T	T	-	-	-	0.9876	benign	-	1	-	-	-	-	-	-
.	10:3138811-3138811	G	stop_lost	HIGH	PITRM1	ENSG00000107959	Transcript	ENST00000455371.5	protein_coding	4/4	-	-	-	553	553	185	*/Q	Tag/Cag	rs2279217,COSV56525502	-	-1	cds_start_NF	HGNC	HGNC:17663	-	-	2	-	-	Ensembl	-	A	A	-	-	-	0.6953	-	0,1	0,1	-	-	-	-	-	-
.	10:6825217-6825217	G	stop_lost	HIGH	LOC107984203	107984203	Transcript	XM_017017016.2	protein_coding	2/2	-	-	-	2017	1309	437	*/R	Tga/Cga	-	-	-1	-	EntrezGene	-	-	-	-	-	-	RefSeq	-	A	A	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	ENSG00000107863	Transcript	ENST00000376410.7	protein_coding	25/25	-	-	-	5145-5146	4688-4689	1563	H/X	cAT/c	-	-	-1	-	HGNC	HGNC:23725	-	-	5	A2	-	Ensembl	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	ENSG00000107863	Transcript	ENST00000396432.7	protein_coding	26/26	-	-	-	5424-5425	4718-4719	1573	H/X	cAT/c	-	-	-1	-	HGNC	HGNC:23725	NM_020824.4	-	1	P3	-	Ensembl	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	ENSG00000107863	Transcript	ENST00000612832.4	protein_coding	19/19	-	-	-	3552-3553	3062-3063	1021	H/X	cAT/c	-	-	-1	-	HGNC	HGNC:23725	-	-	5	-	-	Ensembl	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	ENSG00000107863	Transcript	ENST00000680286.1	protein_coding	25/25	-	-	-	4774-4775	4739-4740	1580	H/X	cAT/c	-	-	-1	-	HGNC	HGNC:23725	-	-	-	A2	-	Ensembl	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367447.1	protein_coding	25/25	-	-	-	5394-5395	4688-4689	1563	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367448.1	protein_coding	26/26	-	-	-	5163-5164	4718-4719	1573	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367449.1	protein_coding	27/27	-	-	-	5209-5210	4424-4425	1475	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367450.1	protein_coding	28/28	-	-	-	5534-5535	4424-4425	1475	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367451.1	protein_coding	25/25	-	-	-	5133-5134	4688-4689	1563	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367452.1	protein_coding	23/23	-	-	-	4882-4883	4247-4248	1416	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367453.1	protein_coding	25/25	-	-	-	5331-5332	4688-4689	1563	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367454.1	protein_coding	26/26	-	-	-	5307-5308	4718-4719	1573	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_001367455.1	protein_coding	19/19	-	-	-	4304-4305	4079-4080	1360	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	NM_020824.4	protein_coding	26/26	-	-	-	5424-5425	4718-4719	1573	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	ENST00000396432.7	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_011519602.3	protein_coding	27/27	-	-	-	5526-5527	4820-4821	1607	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_011519603.4	protein_coding	27/27	-	-	-	5463-5464	4820-4821	1607	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_011519604.3	protein_coding	27/27	-	-	-	5265-5266	4820-4821	1607	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_011519605.3	protein_coding	26/26	-	-	-	5496-5497	4790-4791	1597	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_011519606.3	protein_coding	24/24	-	-	-	6932-6933	4616-4617	1539	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_047425556.1	protein_coding	26/26	-	-	-	5433-5434	4790-4791	1597	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:24585568-24585571	-	frameshift_variant	HIGH	ARHGAP21	57584	Transcript	XM_047425557.1	protein_coding	26/26	-	-	-	5235-5236	4790-4791	1597	H/X	cAT/c	-	-	-1	-	EntrezGene	HGNC:23725	-	-	-	-	-	RefSeq	-	AT	AT	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	ENSG00000183621	Transcript	ENST00000331737.10	protein_coding	6/8	-	-	-	460	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	HGNC	HGNC:21029	-	-	1	P2	-	Ensembl	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	ENSG00000183621	Transcript	ENST00000452305.5	protein_coding	7/9	-	-	-	565	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	HGNC	HGNC:21029	-	-	5	P2	-	Ensembl	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	220929	Transcript	NM_001143770.2	protein_coding	7/9	-	-	-	493	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	EntrezGene	HGNC:21029	-	-	-	-	-	RefSeq	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	220929	Transcript	NM_001143771.2	protein_coding	6/8	-	-	-	464	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	EntrezGene	HGNC:21029	-	-	-	-	-	RefSeq	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	220929	Transcript	XM_006717399.4	protein_coding	6/8	-	-	-	412	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	EntrezGene	HGNC:21029	-	-	-	-	-	RefSeq	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	220929	Transcript	XM_011519376.3	protein_coding	7/9	-	-	-	591	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	EntrezGene	HGNC:21029	-	-	-	-	-	RefSeq	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:30857686-30857686	C	start_lost	HIGH	ZNF438	220929	Transcript	XM_011519377.3	protein_coding	7/9	-	-	-	587	1	1	M/V	Atg/Gtg	rs16932010,COSV59192850	-	-1	-	EntrezGene	HGNC:21029	-	-	-	-	-	RefSeq	-	T	T	-	tolerated_low_confidence(0.2)	benign(0.006)	0.1651	-	0,1	1,1	36224396	-	-	-	-	-
.	10:38362239-38362239	C	splice_acceptor_variant,non_coding_transcript_variant	HIGH	HSD17B7P2	ENSG00000099251	Transcript	ENST00000471365.1	transcribed_unprocessed_pseudogene	-	2/8	-	-	-	-	-	-	-	-	-	1	-	HGNC	HGNC:28120	-	-	-	-	-	Ensembl	-	G	G	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:38362239-38362239	C	splice_acceptor_variant,non_coding_transcript_variant	HIGH	HSD17B7P2	ENSG00000290439	Transcript	ENST00000494540.5	lncRNA	-	2/7	-	-	-	-	-	-	-	-	-	1	-	HGNC	HGNC:28120	-	-	1	-	-	Ensembl	-	G	G	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:38362239-38362239	C	splice_acceptor_variant,non_coding_transcript_variant	HIGH	HSD17B7P2	158160	Transcript	NR_003086.1	transcribed_pseudogene	-	2/7	-	-	-	-	-	-	-	-	-	1	-	EntrezGene	HGNC:28120	-	-	-	-	-	RefSeq	-	G	G	OK	-	-	-	-	-	-	-	-	-	-	-	-
.	10:38651226-38651226	C	splice_donor_variant,non_coding_transcript_variant	HIGH	SLC9B1P3	ENSG00000233867	Transcript	ENST00000452667.2	unprocessed_pseudogene	-	5/8	-	-	-	-	-	-	-	rs3970187	-	-1	-	HGNC	HGNC:43582	-	-	-	-	-	Ensembl	-	A	A	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:42823211-42823211	T	stop_gained	HIGH	BMS1	ENSG00000165733	Transcript	ENST00000374518.6	protein_coding	20/23	-	-	-	3295	3226	1076	R/*	Cga/Tga	rs200996070,COSV65733132	-	1	-	HGNC	HGNC:23505	NM_014753.4	-	1	P1	-	Ensembl	-	C	C	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:42823211-42823211	T	stop_gained	HIGH	BMS1	9790	Transcript	NM_014753.4	protein_coding	20/23	-	-	-	3295	3226	1076	R/*	Cga/Tga	rs200996070,COSV65733132	-	1	-	EntrezGene	HGNC:23505	ENST00000374518.6	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:42823211-42823211	T	stop_gained	HIGH	BMS1	9790	Transcript	XM_005271846.4	protein_coding	20/23	-	-	-	3463	3226	1076	R/*	Cga/Tga	rs200996070,COSV65733132	-	1	-	EntrezGene	HGNC:23505	-	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:42823211-42823211	T	stop_gained	HIGH	BMS1	9790	Transcript	XM_011540402.3	protein_coding	20/23	-	-	-	3315	3226	1076	R/*	Cga/Tga	rs200996070,COSV65733132	-	1	-	EntrezGene	HGNC:23505	-	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:42823211-42823211	T	stop_gained	HIGH	BMS1	9790	Transcript	XM_047426040.1	protein_coding	19/22	-	-	-	3274	3037	1013	R/*	Cga/Tga	rs200996070,COSV65733132	-	1	-	EntrezGene	HGNC:23505	-	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000311652.11	protein_coding	1/8	-	-	-	55-56	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	HGNC	HGNC:23466	-	-	1	-	-	Ensembl	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000374056.10	protein_coding	1/7	-	-	-	453-454	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	HGNC	HGNC:23466	-	-	1	A2	-	Ensembl	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000412531.7	protein_coding	1/8	-	-	-	365-366	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	HGNC	HGNC:23466	NM_001077665.3	-	1	P2	-	Ensembl	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000679810.1	protein_coding	1/9	-	-	-	403-404	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	HGNC	HGNC:23466	-	-	-	-	-	Ensembl	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant,NMD_transcript_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000680115.1	nonsense_mediated_decay	1/10	-	-	-	55-56	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	HGNC	HGNC:23466	-	-	-	-	-	Ensembl	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:49988768-49988770	C	frameshift_variant	HIGH	AGAP6	414189	Transcript	NM_001077665.3	protein_coding	1/8	-	-	-	365-366	55-56	19	Q/PX	cag/cCag	COSV65017401	-	1	-	EntrezGene	HGNC:23466	ENST00000412531.7	-	-	-	-	RefSeq	-	-	-	-	-	-	-	-	1	1	-	-	-	-	-	-
.	10:50008914-50008917	-	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000374056.10	protein_coding	7/7	-	-	-	1120-1121	722-723	241	K/X	aAA/a	rs113234838,COSV65017251	-	1	-	HGNC	HGNC:23466	-	-	1	A2	-	Ensembl	-	AA	AA	-	-	-	-	benign	0,1	1,1	-	-	-	-	-	-
.	10:50008914-50008917	-	frameshift_variant	HIGH	AGAP6	ENSG00000204149	Transcript	ENST00000412531.7	protein_coding	8/8	-	-	-	1101-1102	791-792	264	K/X	aAA/a	rs113234838,COSV65017251	-	1	-	HGNC	HGNC:23466	NM_001077665.3	-	1	P2	-	Ensembl	-	AA	AA	-	-	-	-	benign	0,1	1,1	-	-	-	-	-	-
.	10:50008914-50008917	-	frameshift_variant	HIGH	AGAP6	414189	Transcript	NM_001077665.3	protein_coding	8/8	-	-	-	1101-1102	791-792	264	K/X	aAA/a	rs113234838,COSV65017251	-	1	-	EntrezGene	HGNC:23466	ENST00000412531.7	-	-	-	-	RefSeq	-	AA	AA	-	-	-	-	benign	0,1	1,1	-	-	-	-	-	-
.	10:63153553-63153553	T	stop_gained	HIGH	NRBF2	ENSG00000148572	Transcript	ENST00000277746.11	protein_coding	4/4	-	-	-	342	199	67	Q/*	Cag/Tag	rs1439323425	-	1	-	HGNC	HGNC:19692	NM_030759.5	-	1	P1	-	Ensembl	-	C	C	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:63153553-63153553	T	stop_gained	HIGH	NRBF2	ENSG00000148572	Transcript	ENST00000435510.6	protein_coding	3/3	-	-	-	338	169	57	Q/*	Cag/Tag	rs1439323425	-	1	-	HGNC	HGNC:19692	-	-	2	-	-	Ensembl	-	C	C	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:63153553-63153553	T	stop_gained	HIGH	NRBF2	29982	Transcript	NM_001282405.2	protein_coding	3/3	-	-	-	257	169	57	Q/*	Cag/Tag	rs1439323425	-	1	-	EntrezGene	HGNC:19692	-	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:63153553-63153553	T	stop_gained	HIGH	NRBF2	29982	Transcript	NM_030759.5	protein_coding	4/4	-	-	-	342	199	67	Q/*	Cag/Tag	rs1439323425	-	1	-	EntrezGene	HGNC:19692	ENST00000277746.11	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:63153553-63153553	T	stop_gained	HIGH	NRBF2	29982	Transcript	XM_047425132.1	protein_coding	3/3	-	-	-	213	67	23	Q/*	Cag/Tag	rs1439323425	-	1	-	EntrezGene	HGNC:19692	-	-	-	-	-	RefSeq	-	C	C	-	-	-	-	-	-	-	-	-	-	-	-	-
.	10:72204485-72204485	C	stop_gained	HIGH	ASCC1	ENSG00000138303	Transcript	ENST00000342444.8	protein_coding	4/13	-	-	-	335	233	78	S/*	tCa/tGa	rs11000217,CM1511494,COSV57728881	-	-1	-	HGNC	HGNC:24268	-	-	2	-	-	Ensembl	-	G	G	-	-	-	0.1164	benign	0,0,1	1,1,1	26924529	-	-	-	-	-
.	10:72204485-72204485	C	stop_gained	HIGH	ASCC1	ENSG00000138303	Transcript	ENST00000394915.7	protein_coding	4/12	-	-	-	540	233	78	S/*	tCa/tGa	rs11000217,CM1511494,COSV57728881	-	-1	-	HGNC	HGNC:24268	-	-	5	-	-	Ensembl	-	G	G	-	-	-	0.1164	benign	0,0,1	1,1,1	26924529	-	-	-	-	-
.	10:72204485-72204485	C	stop_gained,NMD_transcript_variant	HIGH	ASCC1	ENSG00000138303	Transcript	ENST00000461369.6	nonsense_mediated_decay	1/5	-	-	-	21	23	8	S/*	tCa/tGa	rs11000217,CM1511494,COSV57728881	-	-1	cds_start_NF	HGNC	HGNC:24268	-	-	3	-	-	Ensembl	-	G	G	-	-	-	0.1164	benign	0,0,1	1,1,1	26924529	-	-	-	-	-
.	10:72204485-72204485	C	stop_gained	HIGH	ASCC1	51008	Transcript	NM_001198799.3	protein_coding	4/13	-	-	-	336	233	78	S/*	tCa/tGa	rs11000217,CM1511494,COSV57728881	-	-1	-	EntrezGene	HGNC:24268	-	-	-	-	-	RefSeq	-	G	G	-	-	-	0.1164	benign	0,0,1	1,1,1	26924529	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000371953.8	protein_coding	1/9	-	-	-	847	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	NM_000314.8	-	1	P1	-	Ensembl	-	T	T	-	deleterious(0)	probably_damaging(0.92)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000472832.3	protein_coding	1/8	-	-	-	143	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	2	-	-	Ensembl	-	T	T	-	deleterious(0)	possibly_damaging(0.872)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost,NMD_transcript_variant	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000686459.1	nonsense_mediated_decay	1/10	-	-	-	144	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	deleterious_low_confidence(0)	probably_damaging(0.977)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000688308.1	protein_coding	2/10	-	-	-	494	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	P1	-	Ensembl	-	T	T	-	deleterious(0)	probably_damaging(0.92)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost,NMD_transcript_variant	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000688922.2	nonsense_mediated_decay	1/10	-	-	-	143	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	deleterious_low_confidence(0)	probably_damaging(0.917)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000700021.1	protein_coding	1/8	-	-	-	677	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	deleterious(0)	benign(0.045)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost,NMD_transcript_variant	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000700022.1	nonsense_mediated_decay	1/8	-	-	-	393	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	deleterious_low_confidence(0)	possibly_damaging(0.697)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000700029.2	protein_coding	1/10	-	-	-	847	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	-	-	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost,NMD_transcript_variant	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000706955.1	nonsense_mediated_decay	1/11	-	-	-	847	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	deleterious_low_confidence(0)	benign(0.095)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost,NMD_transcript_variant	HIGH	PTEN	ENSG00000171862	Transcript	ENST00000710265.1	nonsense_mediated_decay	1/10	-	-	-	847	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	HGNC	HGNC:9588	-	-	-	-	-	Ensembl	-	T	T	-	-	-	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:87864471-87864471	G	start_lost	HIGH	PTEN	5728	Transcript	NM_000314.8	protein_coding	1/9	-	-	-	847	2	1	M/R	aTg/aGg	COSV105289760,COSV64290003,COSV64299893	-	1	-	EntrezGene	HGNC:9588	ENST00000371953.8	-	-	-	-	RefSeq	-	T	T	-	deleterious(0)	probably_damaging(0.92)	-	-	1,1,1	1,1,1	-	-	-	-	-	-
.	10:122454839-122454839	T	stop_gained	HIGH	ARMS2	ENSG00000254636	Transcript	ENST00000528446.1	protein_coding	1/2	-	-	-	187	112	38	R/*	Cga/Tga	rs2736911,CM083592,COSV73306995	-	1	-	HGNC	HGNC:32685	NM_001099667.3	-	1	P1	-	Ensembl	-	C	C	-	-	-	0.1144	benign	0,0,1	1,1,1	18162041,22303384,16080115,17903299,19958499,20961462,23289807,20157352,19259132,23687431,26171855,21958005,16642439,19933179,22293892,24013816,21252205,18164066,20140183,23644223,18688167,20664794,21203342,23572227,23592919,25074467,28128407,19268887,28086806,27879347,27147087,28583181,32328755,36615095	-	-	-	-	-
.	10:122454839-122454839	T	stop_gained	HIGH	ARMS2	387715	Transcript	NM_001099667.3	protein_coding	1/2	-	-	-	187	112	38	R/*	Cga/Tga	rs2736911,CM083592,COSV73306995	-	1	-	EntrezGene	HGNC:32685	ENST00000528446.1	-	-	-	-	RefSeq	-	C	C	-	-	-	0.1144	benign	0,0,1	1,1,1	18162041,22303384,16080115,17903299,19958499,20961462,23289807,20157352,19259132,23687431,26171855,21958005,16642439,19933179,22293892,24013816,21252205,18164066,20140183,23644223,18688167,20664794,21203342,23572227,23592919,25074467,28128407,19268887,28086806,27879347,27147087,28583181,32328755,36615095	-	-	-	-	-
.	10:133625101-133625101	C	stop_lost	HIGH	FRG2B	ENSG00000225899	Transcript	ENST00000425520.2	protein_coding	4/4	-	-	-	888	835	279	*/G	Tga/Gga	rs370574049,COSV71042519	-	-1	-	HGNC	HGNC:33518	NM_001080998.2	-	1	A2	-	Ensembl	-	A	A	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:133625101-133625101	C	stop_lost	HIGH	FRG2B	ENSG00000225899	Transcript	ENST00000443774.5	protein_coding	4/4	-	-	-	888	838	280	*/G	Tga/Gga	rs370574049,COSV71042519	-	-1	-	HGNC	HGNC:33518	-	-	1	P4	-	Ensembl	-	A	A	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-
.	10:133625101-133625101	C	stop_lost	HIGH	FRG2B	441581	Transcript	NM_001080998.2	protein_coding	4/4	-	-	-	888	835	279	*/G	Tga/Gga	rs370574049,COSV71042519	-	-1	-	EntrezGene	HGNC:33518	ENST00000425520.2	-	-	-	-	RefSeq	-	A	A	-	-	-	-	-	0,1	0,1	-	-	-	-	-	-