>SYQ_ECOLI/1-551 Glutamine--tRNA ligase
MSEA---------------EARPTN------------------FIRQIID----------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
--------------------E-DLAS------------G--------------------KHTTVHTRFPPEP
NGYLHIGHAKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSDYFDQLH
AYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEKMRAGGFEEGKACLRAKIDMA
SPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPV
HPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIE
MASLESCIREDLNENAPRAMAVIDPVKLVIENYQ-GEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRADFRE
EANKQYKRLVLGKEVRLRN-AYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHAL
PVEIR--LYDRLFSVPNPGA----ADDFLSVINPESL-VIKQGFAEPSLKDAVAGKAFQFEREGYFCLDSRH
S-------------------------------------------------------------TAE-------
------------------------------------------------------------------------
---------------------------------------------------------K--------------
------------------------------------------------------------------------
------------------------------------------------------------------------
----------------------------------PV------------------------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
---------------FNRTV----------------------------------------------------
-----------GLRD---------------------------------------------------------
---------------------------------TW-----------------A-------------------
--------------------------K
>SYQ_HUMAN/1-774 Glutamine--tRNA ligase
MAALDSLSLFTS-LGLSEQKARETLKNSALSAQLREAATQAQQTLGSTIDKATGILLYGLASRLRDTRRLSF
LVSY-IASKKIHTEPQLSAALEYVRSHPLDPIDTVDFERECGVGVIVTPEQIEEAVEAAINRHRPQLLVERY
HFNMGLLMGEARAVLKWADG--------KMIKNEVDMQVLHLLGPKLEADLEKKFKVAKARLEETDRRTAKD
VVENGETADQTLSLMEQLRGE-ALKFHKPGENY--KTPGYVVTPHTMNLLKQHLEI---TGGQVRTRFPPEP
NGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAICDMVAWLGYT-PYKVTYASDYFDQLY
AWAVELIRRGLAYVCHQRGEELKGHN---T---LPSPWRDRPMEESLLLFEAMRKGKFSEGEATLRMKLVME
DG---KMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVY-
CPVQWEYGRLNLHYAVVSKRKILQLVATGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTME
PHLLEACVRDVLNDTAPRAMAVLESLRVIITNFPAAKSLDIQVPNFPADETKGFHQVPFAPIVFIERTDFKE
EPEPGFKRLAWGQPVGLRHTGYVIELQHVVKGPSGCVESLEVT------CRRADAGEKPKAFIHWVSQ--PL
MCEVR--LYERLFQHKNPEDPTEVPGGFLSDLNLASLHVVDAALVDCSVALAKPFDKFQFERLGYFSVDPD-
S-------------------------------------------------------------HQG-------
------------------------------------------------------------------------
---------------------------------------------------------K--------------
------------------------------------------------------------------------
------------------------------------------------------------------------
----------------------------------LV------------------------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
---------------FNRTV----------------------------------------------------
-----------TLKE---------------------------------------------------------
---------------------------------DP-----------------G-------------------
--------------------------K
>SYEP_HUMAN/1-1503 Bifunctional glutamate/proline--tRNA ligase
MATLSL-TVNSGDPPLGALLAVEHVKDD-VSISVEE-------GKENILHVSENVIFTDVNSILRYLARVAT
TAGLYGSNLMEHTEIDH--WLEFS----------------------ATKLSSCDSFTSTINELNHCLSLRTY
LVGNSLSLADL---CVWATLKGNAAWQEQLKQKKAPVHVKRWFGF-LE------------------------
--------------------AQQ-AFQSVGTKWDVSTTKARVAPEKKQDVGKFVELPGAEMGKVTVRFPPEA
SGYLHIGHAKAALLNQHYQVNFKGKLIMRFDDTNPEKEKEDFEKVILEDVAMLHIK-PDQFTYTSDHFETIM
KYAEKLIQEGKAYVDDTPAEQMKAEREQ-R---IDSKHRKNPIEKNLQMWEEMKKGSQFGQSCCLRAKIDMS
SNNGCMRDPTLYRCKIQPHPRTGNKYNVYPTYDFACPIVDSIEGVTHALRTTEYHDRDEQFYWIIEALGIR-
KPYIWEYSRLNLNNTVLSKRKLTWFVNEGLVDGWDDPRFPTVRGVLRRGMTVEGLKQFIAAQGSSRSVVNME
WDKIWAFNKKVIDPVAPRYVALLKKE-VIPVNVPEAQEEMKEVAKHPKNPEVGLKPVWYSPKVFIEGADAET
F--------SEGEMVTFIN-WGNLNITKIHKNADGKIISLDAK-----LNLENKDYKKTTKVTWLAETTHAL
PIPVICVTYEHLITKPVLGK----DEDFKQYVNKNSK-HEELMLGDPCLKDLKKGDIIQLQRRGFFICDQPY
EPVSPYSCKEAPCVLIYIPDGHTKEMPTSGSKEKTKVEATKNETSAPFKERPTPSLNNNCTTSEDSLVLYNR
VAVQGDVVRELKAKKAPKEDVDAAVKQLLSLKAEYKEKTGQEYKPGNPPAEIGQNISSNSSASILESKSLYD
EVAAQGEVVRKLKAEKSPKAKINEAVECLLSLKAQYKEKTGKEYIPGQPPLSQSSDSSPTRNSEPAGLETPE
AKVLFDKVASQGEVVRKLKTEKAPKDQVDIAVQELLQLKAQYKSLIGVEYKPVSATGAEDKDKKKKEKENKS
EKQNKPQKQNDGQRKDPSKNQGGGLSSSGAGEGQGPKKQTRLGLEAKKEENLADWYSQVITKSEMIEYHDIS
GCYILRPWAYAIWEAIKDFFDAEIKKLGVENCYFPMFVSQSALEKEKTHVADFAPEVAWVTRSGKTELAEPI
AIRPTSETVMYPAYAKWVQSHRDLPIKLNQWCNVVRWEFKHPQPFLRTREFLWQEGHSAFATMEEAAEEVLQ
ILDLYAQVYEELLAIPVVKGRKTEKEKFAGGDYTTTIEAFISASGRAIQGGTSHHLGQNFSKMFEIVFEDPK
IPGEKQFAYQNSWGLTTRTIGVMTMVHGDNMGLVLPPRVACVQVVIIPCGITNALSEEDKEALIAKCNDYRR
RLLSVNIRVRADLRDNYSPGWKFNHWELKGVPIRLEVGPRDMKSCQFVAVRRDTGEKLTVAENEAETKLQAI
LEDIQVTLFTRASEDLKTHMVVANTMEDFQKILDSGKIVQIPFCGEIDCEDWIKKTTARDQDLEPGAPSMGA
KSLCIPFKPLCELQPGAKCVCGKNPAK
>SYQ_RAT/1-774 Glutamine--tRNA ligase
MATPDSLALFTG-LGLSENKARETLKNAALSTQLREAATQAQQTLGSTIDKATGTLLYGLASRLRDTRRLSF
LVGY-IANKKIHTELQLSAALEYVRSHPLDPIDTKDFEQECGVGVVVTPEQIEEAVEATINRHRPQLLVERY
RFSMGLLMGEARAALRWADG--------KMIKNEVDMQVLHLLGPKMEADLEKKPKVAKARLEETDRKTAKD
VVENGEVAGQTLSLMEQLRGE-ALKFHKPGENY--KTPGYVTTPHTMDLLKQHLEI---TGGQVRTRFPPEP
NGILHIGHAKAINFNFGYAKANNGICFLRFDDTNPEKEEAKFFTAIYDMVTWLGYT-PYKVTYASDYFDQLY
AWAVELIRRGQAYVCHQRGEELKGHN---P---LPSPWRDRPIEESLLLFEAMRKGKFAEGEATLRMKLVME
DG---KMDPVAYRVKYTPHHRTGDKWCIYPTYDYTHCLCDSIEHITHSLCTKEFQARRSSYFWLCNALDVY-
CPVQWEYGRLNLHYAVVSKRKILQLVAAGAVRDWDDPRLFTLTALRRRGFPPEAINNFCARVGVTVAQTTME
PHLLEACVRDVLNDTAPRAMAVLEPLQVVITNFPAPKPLDIRVPNFPADETKGFHQVPFASTVFIERTDFKE
ESEPGYKRLAWGQPVGLRHTGYVIELQHVVRGSSGCVECLEVT------CRRADAGEKPKAFIHWVSQ--PL
VCEIR--LYERLFQHKNPEDPVEVPGGFLSDLNPASLQVIKGALVDCSVALAKPFDKFQFERLGYFSVDPD-
S-------------------------------------------------------------HQG-------
------------------------------------------------------------------------
---------------------------------------------------------Q--------------
------------------------------------------------------------------------
------------------------------------------------------------------------
----------------------------------VV------------------------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
---------------FNRTV----------------------------------------------------
-----------TLKE---------------------------------------------------------
---------------------------------DP-----------------G-------------------
--------------------------K
>SYQ_SALEP/1-552 Glutamine--tRNA ligase
MSEA---------------EARPTN------------------FIRQIID----------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
--------------------E-DLAS------------G--------------------KHTTVHTRFPPEP
NGYLHIGHAKSICLNFGIAQDYQGQCNLRFDDTNPVKEDIEYVDSIKNDVEWLGFHWSGDIRYSSDYFDQLH
AYAVELINKGLAYVDELTPEQIREYRGTLTAPGKNSPFRDRSVEENLALFEKMRTGGFEEGKACLRAKIDMA
SPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNITIPV
HPRQYEFSRLNLEYTVMSKRKLNLLVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIE
MASLESCIREDLNENAPRAMAVIDPVKLVIENYPQGESEMVTMPNHPNKPEMGSREVPFSGEIWIDRADFRE
EANKQYKRLVMGKEVRLRN-AYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADGRKVKGVIHWVSAAHAL
PIEIR--LYDRLFSVPNPGA----AEDFLSVINPESL-VIKQGYGEPSLKAAVAGKAFQFEREGYFCLDSRY
A-------------------------------------------------------------TAD-------
------------------------------------------------------------------------
---------------------------------------------------------K--------------
------------------------------------------------------------------------
------------------------------------------------------------------------
----------------------------------LV------------------------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
---------------FNRTV----------------------------------------------------
-----------GLRD---------------------------------------------------------
---------------------------------TW-----------------A-------------------
--------------------------K
>SYQ_YERPY/1-551 Glutamine--tRNA ligase
MSEA---------------EARPSN------------------FIRQIID----------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
--------------------E-DLAS------------G--------------------KHTSVHTRFPPEP
NGYLHIGHAKSICLNFGIAEDYQGQCNLRFDDTNPVKEDVEFVESIKRDVEWLGFTWSGDVRYSSDYFDQLY
QYAVELINKGLAYVDELTPEQMREYRGTLTAPGKNSPYRDRSVEENLVLFEKMRAGGFAEGTACLRAKIDMA
SPFIVMRDPVLYRIKFAEHHQSGNKWCIYPMYDFTHCISDALEGITHSLCTLEFQDNRRLYDWVLDNISIDC
HPRQYEFSRLNLEYTIMSKRKLNQLVTEKVVEGWDDPRMPTISGLRRRGYTAASIREFCRRIGVTKQDNNVE
MMSLESCIRDDLNEHAPRAMAVLDPIKVVIENRA-AGEEWLTMPNHPNNPEMGSRQVPFDSEIYIDRADFRE
EANKQYKRLVLGKEVRLRN-AYVIKAERVEKDAEGNVTTLYCSYDAETLNKDPADGRKVKGVIHWVSVAHAL
PAEIR--LYDRLFNVPNPAA----AEDFLSTINPESL-VIRQGFVEPSLADAVSDKTYQFEREGYFCADSRY
S-------------------------------------------------------------RPG-------
------------------------------------------------------------------------
---------------------------------------------------------A--------------
------------------------------------------------------------------------
------------------------------------------------------------------------
----------------------------------LV------------------------------------
------------------------------------------------------------------------
------------------------------------------------------------------------
---------------FNRTV----------------------------------------------------
-----------GLRD---------------------------------------------------------
---------------------------------TW-----------------A-------------------
--------------------------A
