BLASTP 2.2.28+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: all.fasta 17,018 sequences; 5,095,205 total letters Query= sp|P50866|CLPX_BACSU ATP-dependent Clp protease ATP-binding subunit ClpX OS=Bacillus subtilis (strain 168) GN=clpX PE=2 SV=3 Length=420 Score E Sequences producing significant alignments: (Bits) Value sp|Q8Y7K9|CLPX_LISMO ATP-dependent Clp protease ATP-binding sub... 683 0.0 sp|Q8CNY5|CLPX_STAES ATP-dependent Clp protease ATP-binding sub... 609 0.0 sp|Q6GG31|CLPX_STAAR ATP-dependent Clp protease ATP-binding sub... 607 0.0 sp|Q8GJP6|CLPX_LACLM ATP-dependent Clp protease ATP-binding sub... 566 0.0 tr|J7M389|J7M389_STRP1 ATP-dependent Clp protease ATP-binding s... 547 0.0 sp|P63793|CLPX_STRP1 ATP-dependent Clp protease ATP-binding sub... 547 0.0 sp|P63791|CLPX_STRPN ATP-dependent Clp protease ATP-binding sub... 541 0.0 tr|Q1GAP8|Q1GAP8_LACDA ATP-dependent Clp protease ATP-binding s... 535 0.0 tr|Q1GAP8|Q1GAP8_LACDA ATP-dependent Clp protease ATP-binding s... 535 0.0 sp|Q8CPH0|HSLU_STAES ATP-dependent protease ATPase subunit HslU... 99.0 8e-23 sp|Q8Y7J8|HSLU_LISMO ATP-dependent protease ATPase subunit HslU... 97.8 2e-22 sp|Q6GHI1|HSLU_STAAR ATP-dependent protease ATPase subunit HslU... 97.8 2e-22 sp|Q1G9V4|HSLU_LACDA ATP-dependent protease ATPase subunit HslU... 97.1 3e-22 sp|Q1G9V4|HSLU_LACDA ATP-dependent protease ATPase subunit HslU... 97.1 3e-22 tr|A0A0H2USJ7|A0A0H2USJ7_STRPN ATP-dependent Clp protease, ATP-... 59.3 8e-10 sp|Q6GDQ0|CLPL_STAAR ATP-dependent Clp protease ATP-binding sub... 55.1 2e-08 tr|A2RIW9|A2RIW9_LACLM ATP-dependent Clp protease ATP-binding s... 53.9 4e-08 sp|Q6GJE4|CLPC_STAAR ATP-dependent Clp protease ATP-binding sub... 53.9 5e-08 tr|Q8Y8B1|Q8Y8B1_LISMO ATP-dependent protease OS=Listeria monoc... 52.4 2e-07 sp|Q8CQ88|CLPC_STAES ATP-dependent Clp protease ATP-binding sub... 52.4 2e-07 tr|Q8YAB6|Q8YAB6_LISMO Endopeptidase Clp ATP-binding chain C OS... 52.4 2e-07 tr|Q1G869|Q1G869_LACDA ATP-dependent Clp protease, ATP-binding ... 50.4 5e-07 tr|Q1G869|Q1G869_LACDA ATP-dependent Clp protease, ATP-binding ... 50.4 5e-07 tr|A0A0H2UNL3|A0A0H2UNL3_STRPN Putative ATP-dependent Clp prote... 47.0 7e-06 tr|J7MBF9|J7MBF9_STRP1 Negative regulator of genetic competence... 46.2 1e-05 tr|Q99XR9|Q99XR9_STRP1 Putative endopeptidase Clp ATP-binding c... 46.2 1e-05 tr|Q1GBM8|Q1GBM8_LACDA ATP-dependent Clp protease, ATP-binding ... 45.4 2e-05 tr|Q1GBM8|Q1GBM8_LACDA ATP-dependent Clp protease, ATP-binding ... 45.4 2e-05 tr|J7M6I1|J7M6I1_STRP1 ATP-dependent zinc metalloprotease FtsH ... 45.1 2e-05 tr|Q9A200|Q9A200_STRP1 ATP-dependent zinc metalloprotease FtsH ... 45.1 2e-05 sp|O69076|FTSH_STRPN ATP-dependent zinc metalloprotease FtsH OS... 45.1 3e-05 tr|Q1GBN8|Q1GBN8_LACDA ATP-dependent zinc metalloprotease FtsH ... 44.3 5e-05 tr|Q1GBN8|Q1GBN8_LACDA ATP-dependent zinc metalloprotease FtsH ... 44.3 5e-05 sp|Q6GGZ9|Y1421_STAAR Uncharacterized protein SAR1421 OS=Staphy... 42.0 2e-04 tr|Q8YAC6|Q8YAC6_LISMO ATP-dependent zinc metalloprotease FtsH ... 41.6 3e-04 sp|Q8Y6Z8|RUVB_LISMO Holliday junction ATP-dependent DNA helica... 40.8 4e-04 tr|A2RH93|A2RH93_LACLM ATP-dependent zinc metalloprotease FtsH ... 40.4 7e-04 sp|Q8CP85|Y1092_STAES Uncharacterized protein SE_1092 OS=Staphy... 39.3 0.001 > sp|Q8Y7K9|CLPX_LISMO ATP-dependent Clp protease ATP-binding subunit ClpX OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=clpX PE=3 SV=1 Length=419 Score = 683 bits (1762), Expect = 0.0, Method: Compositional matrix adjust. Identities = 347/421 (82%), Positives = 381/421 (90%), Gaps = 3/421 (1%) Query 1 MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD 60 MFKFN+EKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELC EI+EEELG E V+F + Sbjct 1 MFKFNDEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCNEIIEEELGISEFVDFGE 60 Query 61 VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSN-SKVDDVELSKSNISLIGPTG 119 VPKPQEIR IL++YVIGQ++AKK+LAVAVYNHYKRINSN +K D+VELSKSNI LIGPTG Sbjct 61 VPKPQEIRHILSDYVIGQERAKKALAVAVYNHYKRINSNETKEDEVELSKSNICLIGPTG 120 Query 120 SGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIY 179 SGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQ+ADYDVEKAEKGIIY Sbjct 121 SGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQSADYDVEKAEKGIIY 180 Query 180 IDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTN 239 IDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQE IQIDT N Sbjct 181 IDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQELIQIDTGN 240 Query 240 ILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFI 299 ILFI GGAFDGIEQI+K R+G+KVIGFG DN A + E LS+V+PEDLL+FGLIPEFI Sbjct 241 ILFIVGGAFDGIEQIVKNRMGEKVIGFGTDN-AKLKDDETYLSRVVPEDLLKFGLIPEFI 299 Query 300 GRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIER 359 GRLPVIA+LE+LDE ALV+ILT+PKNALVKQ+K+MLELD+VELEFE AL EIAK+AIER Sbjct 300 GRLPVIATLEQLDEAALVSILTEPKNALVKQYKRMLELDDVELEFEPTALIEIAKEAIER 359 Query 360 KTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTS 419 KTGARGLRSIIE IML+VMFE+PSRDDI KC+IT E P+L L+DG+ + KTS Sbjct 360 KTGARGLRSIIEQIMLEVMFEIPSRDDITKCIITEKAARGEEEPQLQLEDGS-IIPIKTS 418 Query 420 A 420 A Sbjct 419 A 419 > sp|Q8CNY5|CLPX_STAES ATP-dependent Clp protease ATP-binding subunit ClpX OS=Staphylococcus epidermidis (strain ATCC 12228) GN=clpX PE=3 SV=1 Length=420 Score = 609 bits (1570), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/421 (72%), Positives = 357/421 (85%), Gaps = 2/421 (0%) Query 1 MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD 60 MFKFNE++ LKCSFCGK QDQV+KLVAG GVYIC+ECIELC+EIVEEEL F + Sbjct 1 MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEGFTE 60 Query 61 VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINS-NSKVDDVELSKSNISLIGPTG 119 +P P+EI + LNEYVIGQ++AKKSLAVAVYNHYKRI DDVEL KSNI+LIGPTG Sbjct 61 LPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPNEDDVELQKSNIALIGPTG 120 Query 120 SGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIY 179 SGKTLLAQTLA+ LNVPFAIADATSLTEAGYVG+DVENILL+LIQAAD+D++KAEKGIIY Sbjct 121 SGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIY 180 Query 180 IDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTN 239 +DEIDK+ARKSEN SITRDVSGEGVQQALLKILEGT ASVPPQGGRKHP+QE IQIDTTN Sbjct 181 VDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQELIQIDTTN 240 Query 240 ILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFI 299 ILFI GGAFDGI+++IKRRLG+KVIGF A N+A ++E LL ++ PEDL +GLIPEFI Sbjct 241 ILFILGGAFDGIDEVIKRRLGEKVIGF-ASNEADKYDEEALLEQIRPEDLQSYGLIPEFI 299 Query 300 GRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIER 359 GR+P++A+LE LD AL ILT+PKNALVKQ+ KMLELDNVELEF EEALS I++KAIER Sbjct 300 GRVPIVANLETLDVAALKNILTQPKNALVKQYTKMLELDNVELEFSEEALSAISEKAIER 359 Query 360 KTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTS 419 KTGARGLRSIIE ++D+M+++PS +++ K VIT T+ P L +G ++++KTS Sbjct 360 KTGARGLRSIIEEALIDIMYDVPSSENVSKVVITEQTINEEIEPELYDDEGNLINKNKTS 419 Query 420 A 420 A Sbjct 420 A 420 > sp|Q6GG31|CLPX_STAAR ATP-dependent Clp protease ATP-binding subunit ClpX OS=Staphylococcus aureus (strain MRSA252) GN=clpX PE=3 SV=1 Length=420 Score = 607 bits (1566), Expect = 0.0, Method: Compositional matrix adjust. Identities = 301/421 (71%), Positives = 356/421 (85%), Gaps = 2/421 (0%) Query 1 MFKFNEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKD 60 MFKFNE++ LKCSFCGK QDQV+KLVAG GVYIC+ECIELC+EIVEEEL + Sbjct 1 MFKFNEDEENLKCSFCGKDQDQVKKLVAGSGVYICNECIELCSEIVEEELAQNTSEAITE 60 Query 61 VPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINS-NSKVDDVELSKSNISLIGPTG 119 +P P+EI + LNEYVIGQ++AKKSLAVAVYNHYKRI K DDVEL KSNI+LIGPTG Sbjct 61 LPTPKEIMDHLNEYVIGQEKAKKSLAVAVYNHYKRIQQLGPKEDDVELQKSNIALIGPTG 120 Query 120 SGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIY 179 SGKTLLAQTLA+ LNVPFAIADATSLTEAGYVG+DVENILL+LIQAAD+D++KAEKGIIY Sbjct 121 SGKTLLAQTLAKTLNVPFAIADATSLTEAGYVGDDVENILLRLIQAADFDIDKAEKGIIY 180 Query 180 IDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTN 239 +DEIDK+ARKSEN SITRDVSGEGVQQALLKILEGT ASVPPQGGRKHP+QE IQIDTTN Sbjct 181 VDEIDKIARKSENTSITRDVSGEGVQQALLKILEGTTASVPPQGGRKHPNQEMIQIDTTN 240 Query 240 ILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFI 299 ILFI GGAFDGIE++IKRRLG+KVIGF + N+A +++ LL+++ PEDL +GLIPEFI Sbjct 241 ILFILGGAFDGIEEVIKRRLGEKVIGFSS-NEADKYDEQALLAQIRPEDLQAYGLIPEFI 299 Query 300 GRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIER 359 GR+P++A+LE LD AL ILT+PKNALVKQ+ KMLELD+V+LEF EEALS I++KAIER Sbjct 300 GRVPIVANLETLDVTALKNILTQPKNALVKQYTKMLELDDVDLEFTEEALSAISEKAIER 359 Query 360 KTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQDKTS 419 KTGARGLRSIIE ++D+MF++PS +++ K VIT T+ P L +G ++ KTS Sbjct 360 KTGARGLRSIIEESLIDIMFDVPSNENVTKVVITAQTINEETEPELYDAEGNLINNSKTS 419 Query 420 A 420 A Sbjct 420 A 420 > sp|Q8GJP6|CLPX_LACLM ATP-dependent Clp protease ATP-binding subunit ClpX OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=clpX PE=3 SV=1 Length=411 Score = 566 bits (1458), Expect = 0.0, Method: Compositional matrix adjust. Identities = 278/405 (69%), Positives = 346/405 (85%), Gaps = 5/405 (1%) Query 5 NEEKGQLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKP 64 N + ++CSFCGK+QD V+K++AG VYIC+ECIEL T I+EEEL E++ E +V P Sbjct 3 NTQNPNIQCSFCGKSQDDVKKMIAGSDVYICNECIELSTRILEEELKEEQDSEMLEVKTP 62 Query 65 QEIREILNEYVIGQDQAKKSLAVAVYNHYKRIN-SNSKV-DDVELSKSNISLIGPTGSGK 122 +E+ + LNEYVIGQ++AK++LAVAVYNHYKRIN + SK+ +D+EL KSNI LIGPTGSGK Sbjct 63 KEMFDHLNEYVIGQEKAKRALAVAVYNHYKRINFTASKIAEDIELQKSNILLIGPTGSGK 122 Query 123 TLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDE 182 T LAQTLA+ LNVPFAIADATSLTEAGYVGEDVENILLKL+QA+D+++E+AE+GIIYIDE Sbjct 123 TFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLLQASDFNIERAERGIIYIDE 182 Query 183 IDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILF 242 IDK+A+KSEN SITRDVSGEGVQQALLKI+EGTVASVPPQGGRKHP+QE IQIDT NILF Sbjct 183 IDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILF 242 Query 243 ICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKED-LLSKVLPEDLLRFGLIPEFIGR 301 I GGAFDGIE+I+K+RLG+K+IGFGA+NK L ED + +++ ED+ +FGLIPEFIGR Sbjct 243 IVGGAFDGIEEIVKQRLGEKIIGFGANNKK--LSDEDSYMQEIIAEDIQKFGLIPEFIGR 300 Query 302 LPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKT 361 LP++A+LE+L EE L+ ILT+PKNAL+KQ+K++L DNVELEF++ AL IAKKAIERKT Sbjct 301 LPIVAALERLTEEDLIQILTEPKNALIKQYKQLLLFDNVELEFKDGALMAIAKKAIERKT 360 Query 362 GARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLL 406 GARGLRSIIE +M+D+MFE+PS ++I K +IT A V P ++ Sbjct 361 GARGLRSIIEEVMMDIMFEVPSHEEITKVIITEAVVDGKAEPEMI 405 > tr|J7M389|J7M389_STRP1 ATP-dependent Clp protease ATP-binding subunit ClpX OS=Streptococcus pyogenes M1 476 GN=clpX PE=3 SV=2 Length=409 Score = 547 bits (1409), Expect = 0.0, Method: Compositional matrix adjust. Identities = 264/398 (66%), Positives = 332/398 (83%), Gaps = 3/398 (1%) Query 10 QLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIRE 69 ++ CSFCGK+QD V+K++AG V+IC+EC+ L EI++EEL E + +VPKP+E+ + Sbjct 10 KVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLD 69 Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRIN--SNSKVDDVELSKSNISLIGPTGSGKTLLAQ 127 +LN+YV+GQD+AK++L+VAVYNHYKR++ + DDV+L KSNI +IGPTGSGKT LAQ Sbjct 70 VLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQ 129 Query 128 TLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVA 187 TLA+ LNVPFAIADATSLTEAGYVGEDVENILLKLIQAADY+VE+AE+GIIY+DEIDK+A Sbjct 130 TLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIA 189 Query 188 RKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGA 247 +K EN SITRDVSGEGVQQALLKI+EGTVASVPPQGGRKHP+QE IQIDT NILFI GGA Sbjct 190 KKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGA 249 Query 248 FDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIAS 307 FDGIE+I+K+RLG+KVIGFG +++ D + + +++ ED+ +FGLIPEFIGRLPV+A+ Sbjct 250 FDGIEEIVKQRLGEKVIGFGQNSRKID-DNASYMQEIISEDIQKFGLIPEFIGRLPVVAA 308 Query 308 LEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLR 367 LE+L+ L+ ILT+P+NALVKQ++ +L D VEL F++EAL IA KAIERKTGARGLR Sbjct 309 LEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLR 368 Query 368 SIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRL 405 SIIE MLD+MFE+PS++D+ K IT A V P L Sbjct 369 SIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVL 406 > sp|P63793|CLPX_STRP1 ATP-dependent Clp protease ATP-binding subunit ClpX OS=Streptococcus pyogenes serotype M1 GN=clpX PE=3 SV=1 Length=409 Score = 547 bits (1409), Expect = 0.0, Method: Compositional matrix adjust. Identities = 264/398 (66%), Positives = 332/398 (83%), Gaps = 3/398 (1%) Query 10 QLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIRE 69 ++ CSFCGK+QD V+K++AG V+IC+EC+ L EI++EEL E + +VPKP+E+ + Sbjct 10 KVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLD 69 Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRIN--SNSKVDDVELSKSNISLIGPTGSGKTLLAQ 127 +LN+YV+GQD+AK++L+VAVYNHYKR++ + DDV+L KSNI +IGPTGSGKT LAQ Sbjct 70 VLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQ 129 Query 128 TLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVA 187 TLA+ LNVPFAIADATSLTEAGYVGEDVENILLKLIQAADY+VE+AE+GIIY+DEIDK+A Sbjct 130 TLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIA 189 Query 188 RKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGA 247 +K EN SITRDVSGEGVQQALLKI+EGTVASVPPQGGRKHP+QE IQIDT NILFI GGA Sbjct 190 KKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGA 249 Query 248 FDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIAS 307 FDGIE+I+K+RLG+KVIGFG +++ D + + +++ ED+ +FGLIPEFIGRLPV+A+ Sbjct 250 FDGIEEIVKQRLGEKVIGFGQNSRKID-DNASYMQEIISEDIQKFGLIPEFIGRLPVVAA 308 Query 308 LEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLR 367 LE+L+ L+ ILT+P+NALVKQ++ +L D VEL F++EAL IA KAIERKTGARGLR Sbjct 309 LEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLR 368 Query 368 SIIEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRL 405 SIIE MLD+MFE+PS++D+ K IT A V P L Sbjct 369 SIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVL 406 > sp|P63791|CLPX_STRPN ATP-dependent Clp protease ATP-binding subunit ClpX OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=clpX PE=3 SV=1 Length=410 Score = 541 bits (1395), Expect = 0.0, Method: Compositional matrix adjust. Identities = 265/396 (67%), Positives = 328/396 (83%), Gaps = 4/396 (1%) Query 13 CSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILN 72 CSFCGK Q++V+K++AG +IC+EC+EL EI+ EEL E + +VPKP E+ ILN Sbjct 13 CSFCGKNQEEVQKIIAGNNAFICNECVELAQEIIREELVEEVLADLSEVPKPIELLHILN 72 Query 73 EYVIGQDQAKKSLAVAVYNHYKRIN---SNSKVDDVELSKSNISLIGPTGSGKTLLAQTL 129 YVIGQD+AK++LAVAVYNHYKRIN + + +DV+L KSNI +IGPTGSGKT LAQTL Sbjct 73 HYVIGQDRAKRALAVAVYNHYKRINFHDTREESEDVDLQKSNILMIGPTGSGKTFLAQTL 132 Query 130 ARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARK 189 A+ LNVPFAIADAT+LTEAGYVGEDVENILLKL+Q AD+++E+AE+GIIY+DEIDK+A+K Sbjct 133 AKSLNVPFAIADATALTEAGYVGEDVENILLKLLQVADFNIERAERGIIYVDEIDKIAKK 192 Query 190 SENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFD 249 SEN SITRDVSGEGVQQALLKI+EGTVASVPPQGGRKHP QE IQ+DT NILFI GGAFD Sbjct 193 SENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFD 252 Query 250 GIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLE 309 GIE+I+K+RLG+KVIGFG +NKA D E + +++ ED+ +FG+IPE IGRLPV A+LE Sbjct 253 GIEEIVKQRLGEKVIGFGQNNKAID-ENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALE 311 Query 310 KLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSI 369 +L + LV IL +P+NALVKQ++ +L D+VELEF++EAL EIA KAIERKTGARGLRSI Sbjct 312 QLTVDDLVRILKEPRNALVKQYQTLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSI 371 Query 370 IEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRL 405 IE MLDVMFE+PS+++++ IT TV + P L Sbjct 372 IEETMLDVMFEVPSQENVKLVRITKETVDGTDKPIL 407 > tr|Q1GAP8|Q1GAP8_LACDA ATP-dependent Clp protease ATP-binding subunit ClpX OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpX PE=3 SV=1 Length=417 Score = 535 bits (1379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 258/407 (63%), Positives = 331/407 (81%), Gaps = 0/407 (0%) Query 10 QLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIRE 69 ++KCSFCGK+ QV+K++AG GVYIC+E IEL I+++EL + E +++PKP +I+E Sbjct 10 EVKCSFCGKSASQVKKMIAGNGVYICNEDIELAKRIIDDELRLDSLKETRELPKPMQIKE 69 Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTL 129 L++YVIGQD+AK+ L+VAVYNHYKRI+ EL KSNI+LIGPTGSGKT LAQTL Sbjct 70 ELDQYVIGQDRAKRVLSVAVYNHYKRISQIDVDSSTELQKSNIALIGPTGSGKTYLAQTL 129 Query 130 ARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARK 189 ARILNVPFAIADAT+LTEAGYVGEDVENILLKL+Q ADYD+E+A++GIIYIDEIDK+++K Sbjct 130 ARILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYDLERAQRGIIYIDEIDKISKK 189 Query 190 SENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFD 249 SEN SITRDVSGEGVQQALLKILEGT+AS+PPQGGRKHP QE I++DTTNILFI GGAFD Sbjct 190 SENVSITRDVSGEGVQQALLKILEGTIASIPPQGGRKHPQQEMIRMDTTNILFIVGGAFD 249 Query 250 GIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLE 309 GIE+I+K RLG+K IGFGA+ ++ ++ ++ + DL++FGLIPEFIGR+P+I +L+ Sbjct 250 GIEEIVKNRLGKKTIGFGAEQESGKVDDDNWNRFLTTGDLVKFGLIPEFIGRIPIITTLD 309 Query 310 KLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSI 369 +LD LV ILT+PKNAL+KQ++K+L LD V+LEFE A+ +IA AIERK GARGLR+I Sbjct 310 RLDSADLVRILTEPKNALIKQYQKLLSLDGVDLEFEPAAVKQIADLAIERKMGARGLRTI 369 Query 370 IEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQD 416 IE M+D+M+ PS DI K +IT T+T P+++ ++ EV D Sbjct 370 IENAMMDIMYRTPSESDISKIIITPETITGMGEPKVVRRELEEVVDD 416 > tr|Q1GAP8|Q1GAP8_LACDA ATP-dependent Clp protease ATP-binding subunit ClpX OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpX PE=3 SV=1 Length=417 Score = 535 bits (1379), Expect = 0.0, Method: Compositional matrix adjust. Identities = 258/407 (63%), Positives = 331/407 (81%), Gaps = 0/407 (0%) Query 10 QLKCSFCGKTQDQVRKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIRE 69 ++KCSFCGK+ QV+K++AG GVYIC+E IEL I+++EL + E +++PKP +I+E Sbjct 10 EVKCSFCGKSASQVKKMIAGNGVYICNEDIELAKRIIDDELRLDSLKETRELPKPMQIKE 69 Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTL 129 L++YVIGQD+AK+ L+VAVYNHYKRI+ EL KSNI+LIGPTGSGKT LAQTL Sbjct 70 ELDQYVIGQDRAKRVLSVAVYNHYKRISQIDVDSSTELQKSNIALIGPTGSGKTYLAQTL 129 Query 130 ARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVARK 189 ARILNVPFAIADAT+LTEAGYVGEDVENILLKL+Q ADYD+E+A++GIIYIDEIDK+++K Sbjct 130 ARILNVPFAIADATTLTEAGYVGEDVENILLKLLQNADYDLERAQRGIIYIDEIDKISKK 189 Query 190 SENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAFD 249 SEN SITRDVSGEGVQQALLKILEGT+AS+PPQGGRKHP QE I++DTTNILFI GGAFD Sbjct 190 SENVSITRDVSGEGVQQALLKILEGTIASIPPQGGRKHPQQEMIRMDTTNILFIVGGAFD 249 Query 250 GIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLE 309 GIE+I+K RLG+K IGFGA+ ++ ++ ++ + DL++FGLIPEFIGR+P+I +L+ Sbjct 250 GIEEIVKNRLGKKTIGFGAEQESGKVDDDNWNRFLTTGDLVKFGLIPEFIGRIPIITTLD 309 Query 310 KLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLRSI 369 +LD LV ILT+PKNAL+KQ++K+L LD V+LEFE A+ +IA AIERK GARGLR+I Sbjct 310 RLDSADLVRILTEPKNALIKQYQKLLSLDGVDLEFEPAAVKQIADLAIERKMGARGLRTI 369 Query 370 IEGIMLDVMFELPSRDDIEKCVITGATVTHGEPPRLLLKDGTEVSQD 416 IE M+D+M+ PS DI K +IT T+T P+++ ++ EV D Sbjct 370 IENAMMDIMYRTPSESDISKIIITPETITGMGEPKVVRRELEEVVDD 416 > sp|Q8CPH0|HSLU_STAES ATP-dependent protease ATPase subunit HslU OS=Staphylococcus epidermidis (strain ATCC 12228) GN=hslU PE=3 SV=1 Length=467 Score = 99.0 bits (245), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 73/213 (34%), Positives = 108/213 (51%), Gaps = 56/213 (26%) Query 176 GIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQI 235 GII+IDEIDKVA ++N +DVS +GVQ+ +L ILEG++ ++ + Sbjct 275 GIIFIDEIDKVATNNQNSG--QDVSRQGVQRDILPILEGSMI-----------QTKYGTV 321 Query 236 DTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLI 295 +T ++LFI GAF +SK P DL I Sbjct 322 NTEHMLFIGAGAFH-------------------------------VSK--PSDL-----I 343 Query 296 PEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKK 355 PE GR P+ LE L E V ILT+PK +LVKQ++ +L+ + V + F E+A+ +A+ Sbjct 344 PELQGRFPIRVELESLSVEDFVRILTEPKLSLVKQYEALLQTEEVTVNFSEDAIQRLAEI 403 Query 356 AIE-----RKTGARGLRSIIEGIMLDVMFELPS 383 A + GAR L +I+E ++ D+ FE PS Sbjct 404 AYQVNQDTDNIGARRLHTILEKMLEDLSFEAPS 436 Score = 90.5 bits (223), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 46/115 (40%), Positives = 76/115 (66%), Gaps = 1/115 (1%) Query 64 PQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKT 123 P++I LNEY++GQ+ AK+ +A+A+ N Y+R + + + E++ NI +IGPTG GKT Sbjct 10 PKDIVSKLNEYIVGQNDAKRKVAIALRNRYRR-SLLKEEEKQEIAPKNILMIGPTGVGKT 68 Query 124 LLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGII 178 +A+ +A+I+ PF +AT TE GYVG DVE+++ L+ A V+ +K ++ Sbjct 69 EIARRMAKIVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVAVRLVKDEKKSLV 123 > sp|Q8Y7J8|HSLU_LISMO ATP-dependent protease ATPase subunit HslU OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=hslU PE=3 SV=1 Length=469 Score = 97.8 bits (242), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 86/261 (33%), Positives = 128/261 (49%), Gaps = 61/261 (23%) Query 161 KLIQA---ADYDVEKAEK-GIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTV 216 KLI A A + +AE+ G+I+IDEIDK+A K + VS EGVQ+ +L I+EG+ Sbjct 258 KLIDADELAAEGIHRAEQMGMIFIDEIDKIASKEGGGNA--QVSREGVQRDILPIVEGSQ 315 Query 217 ASVPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLE 276 S ++ ++T ILFI GAF Sbjct 316 IST-----------KYGTVNTEYILFIAAGAFH--------------------------- 337 Query 277 KEDLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLE 336 +SK P DL IPE GR P+ L+KL +E ILT+P NAL+KQ+K +L+ Sbjct 338 ----MSK--PSDL-----IPELQGRFPIRIELDKLTQEDFYKILTEPDNALIKQYKALLK 386 Query 337 LDNVELEFEEEALSEIAKKAIE-----RKTGARGLRSIIEGIMLDVMFELPSRDDIEKCV 391 + ++L F +EA+ IA+ A + GAR L +I+E ++ D++FE P ++E Sbjct 387 TEGIDLIFTKEAVERIAEIAFQVNQDSDNIGARRLHTILEKLLEDLLFEAPE-INMESIK 445 Query 392 ITGATVTHGEPPRLLLKDGTE 412 +T V P + KD T+ Sbjct 446 VTENYVNEKLAPIMQNKDLTQ 466 Score = 96.3 bits (238), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 47/103 (46%), Positives = 73/103 (71%), Gaps = 1/103 (1%) Query 64 PQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKT 123 P++I E L++Y+IGQ+ AKKS+AVA+ N Y+R + + D E+ NI +IGPTG GKT Sbjct 12 PKQIVEKLDQYIIGQNGAKKSVAVALRNRYRRQLMDESIRD-EIIPKNILMIGPTGVGKT 70 Query 124 LLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAA 166 +A+ +A+I+ PF+ +AT TE GYVG DVE+++ L++ + Sbjct 71 EIARRIAKIVRAPFSKVEATKFTEVGYVGRDVESMVRDLVEVS 113 > sp|Q6GHI1|HSLU_STAAR ATP-dependent protease ATPase subunit HslU OS=Staphylococcus aureus (strain MRSA252) GN=hslU PE=3 SV=1 Length=467 Score = 97.8 bits (242), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 72/213 (34%), Positives = 108/213 (51%), Gaps = 56/213 (26%) Query 176 GIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQI 235 GII+IDEIDKVA + N +DVS +GVQ+ +L ILEG+V ++ + Sbjct 275 GIIFIDEIDKVATNNHNSG--QDVSRQGVQRDILPILEGSVI-----------QTKYGTV 321 Query 236 DTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLI 295 +T ++LFI GAF +SK P DL I Sbjct 322 NTEHMLFIGAGAFH-------------------------------VSK--PSDL-----I 343 Query 296 PEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKK 355 PE GR P+ L+ L E V ILT+PK +L+KQ++ +L+ + V + F +EA++ +A+ Sbjct 344 PELQGRFPIRVELDSLAVEDFVRILTEPKLSLIKQYEALLQTEEVTVNFTDEAITRLAEI 403 Query 356 AIE-----RKTGARGLRSIIEGIMLDVMFELPS 383 A + GAR L +I+E ++ D+ FE PS Sbjct 404 AYQVNQDTDNIGARRLHTILEKMLEDLSFEAPS 436 Score = 93.6 bits (231), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 48/117 (41%), Positives = 77/117 (66%), Gaps = 5/117 (4%) Query 64 PQEIREILNEYVIGQDQAKKSLAVAVYNHYKR--INSNSKVDDVELSKSNISLIGPTGSG 121 P+EI LNEY++GQ+ AK+ +A+A+ N Y+R ++ SK E+S NI +IGPTG G Sbjct 10 PKEIVSKLNEYIVGQNDAKRKVAIALRNRYRRSLLDEESKQ---EISPKNILMIGPTGVG 66 Query 122 KTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAEKGII 178 KT +A+ +A+++ PF +AT TE GYVG DVE+++ L+ + V+ +K ++ Sbjct 67 KTEIARRMAKVVGAPFIKVEATKFTEVGYVGRDVESMVRDLVDVSVRLVKAQKKSLV 123 > sp|Q1G9V4|HSLU_LACDA ATP-dependent protease ATPase subunit HslU OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=hslU PE=3 SV=1 Length=464 Score = 97.1 bits (240), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 49/111 (44%), Positives = 75/111 (68%), Gaps = 1/111 (1%) Query 64 PQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKT 123 P++I ++L++Y++GQ++AKKS+A+A+YN Y+R V +++ NI + GPTG GKT Sbjct 6 PKQIVDLLDKYIVGQNEAKKSVAIALYNRYRRTQLPEDVQK-DITPKNILMAGPTGVGKT 64 Query 124 LLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAE 174 +A+ LA I++ PF +AT TE GYVG DVE+++ L A VEK E Sbjct 65 EIARRLADIVDAPFVKVEATKFTEVGYVGRDVESMVRDLANEAVRIVEKEE 115 Score = 89.7 bits (221), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 59/225 (26%) Query 174 EKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFI 233 + GII+IDEIDK+ + S VS EGVQ+ +L I+EG+ S ++ Sbjct 270 QSGIIFIDEIDKITAADKRNSA--GVSREGVQRDILPIVEGSTVST-----------KYG 316 Query 234 QIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFG 293 + T +ILFI GAF A++K +D Sbjct 317 PLSTDHILFIAAGAF-------------------AESKPSD------------------- 338 Query 294 LIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 LIPE GR P+ L L ++ V IL P+N+L+KQ+ +L+ D V+L F EA+ +IA Sbjct 339 LIPELQGRFPIRVELNALTKDDFVRILKDPQNSLLKQYIALLKADGVDLVFTAEAVDKIA 398 Query 354 KKAIE-----RKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVIT 393 + A E GAR L +I+E ++ +V++E P D+E IT Sbjct 399 EIAFEVNQGTDNIGARRLATILEKLLEEVLYEGP---DMEMGQIT 440 > sp|Q1G9V4|HSLU_LACDA ATP-dependent protease ATPase subunit HslU OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=hslU PE=3 SV=1 Length=464 Score = 97.1 bits (240), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 49/111 (44%), Positives = 75/111 (68%), Gaps = 1/111 (1%) Query 64 PQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKT 123 P++I ++L++Y++GQ++AKKS+A+A+YN Y+R V +++ NI + GPTG GKT Sbjct 6 PKQIVDLLDKYIVGQNEAKKSVAIALYNRYRRTQLPEDVQK-DITPKNILMAGPTGVGKT 64 Query 124 LLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKAE 174 +A+ LA I++ PF +AT TE GYVG DVE+++ L A VEK E Sbjct 65 EIARRLADIVDAPFVKVEATKFTEVGYVGRDVESMVRDLANEAVRIVEKEE 115 Score = 89.7 bits (221), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 59/225 (26%) Query 174 EKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFI 233 + GII+IDEIDK+ + S VS EGVQ+ +L I+EG+ S ++ Sbjct 270 QSGIIFIDEIDKITAADKRNSA--GVSREGVQRDILPIVEGSTVST-----------KYG 316 Query 234 QIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFG 293 + T +ILFI GAF A++K +D Sbjct 317 PLSTDHILFIAAGAF-------------------AESKPSD------------------- 338 Query 294 LIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 LIPE GR P+ L L ++ V IL P+N+L+KQ+ +L+ D V+L F EA+ +IA Sbjct 339 LIPELQGRFPIRVELNALTKDDFVRILKDPQNSLLKQYIALLKADGVDLVFTAEAVDKIA 398 Query 354 KKAIE-----RKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVIT 393 + A E GAR L +I+E ++ +V++E P D+E IT Sbjct 399 EIAFEVNQGTDNIGARRLATILEKLLEEVLYEGP---DMEMGQIT 440 > tr|A0A0H2USJ7|A0A0H2USJ7_STRPN ATP-dependent Clp protease, ATP-binding subunit OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=SP_2194 PE=3 SV=1 Length=810 Score = 59.3 bits (142), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 91/347 (26%), Positives = 153/347 (44%), Gaps = 74/347 (21%) Query 71 LNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA 130 L++ VIGQDQA S++ A+ + I S+ + + +GPTG GKT LA+ LA Sbjct 510 LHKRVIGQDQAVSSISRAIRRNQSGIRSHKR------PIGSFMFLGPTGVGKTELAKALA 563 Query 131 RILN------VPFAIAD------ATSLTEA--GYVGEDVENILLKLIQAADYDVEKAEKG 176 +L + F +++ A+ L A GYVG + L + ++ Y V Sbjct 564 EVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSV------ 617 Query 177 IIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQID 236 + DE++K +P I LL++L+ V + GRK I I Sbjct 618 -LLFDEVEKA-----HPDIF---------NVLLQVLDDGV--LTDSKGRKVDFSNTIIIM 660 Query 237 TTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIP 296 T+N+ GA K +GFGA K ++E++ ++ E L+ P Sbjct 661 TSNL-----GA--------TALRDDKTVGFGA--KDIRFDQENMEKRMFEE--LKKAYRP 703 Query 297 EFIGRLP---VIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 EFI R+ V SL + +V I+ KP A + + ++L+ + AL +A Sbjct 704 EFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLTE-------KGIDLKLQASALKLLA 756 Query 354 KKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIEKCVITGATVTHG 400 + + + GAR LR ++ + D + EL + D+ + G+T+ G Sbjct 757 NQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDL----VAGSTLKIG 799 > sp|Q6GDQ0|CLPL_STAAR ATP-dependent Clp protease ATP-binding subunit ClpL OS=Staphylococcus aureus (strain MRSA252) GN=clpL PE=3 SV=1 Length=701 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 81/333 (24%), Positives = 142/333 (43%), Gaps = 83/333 (25%) Query 55 EVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISL 114 +++ D+ + + I L +IGQD+A + ++ A+ + + DD + Sbjct 402 QMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRN------RAGFDDGNRPIGSFLF 455 Query 115 IGPTGSGKTLLAQTLA--------RILNVPFA-IADATSL-----TEAGYVG-EDVENIL 159 +GPTG GKT LA+ LA ++ + + +D T++ T AGYVG +D N L Sbjct 456 VGPTGVGKTELAKQLAIDLFGNKEALIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTL 515 Query 160 LKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKIL-EGTVAS 218 + ++ Y V I DEI+K NP I LL+++ +G + Sbjct 516 TEKVRRNPYSV-------ILFDEIEKA-----NPQIL---------TLLLQVMDDGNLTD 554 Query 219 VPPQGGRKHPHQEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKE 278 QG I+ N + IC GFG N D E++ Sbjct 555 --GQGN---------VINFKNTIIICTSN----------------AGFGNGN---DTEEK 584 Query 279 DLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELD 338 D++ ++ +F PEF+ R I LD++AL I+ N L+ + L+ Sbjct 585 DIM-----HEMKKF-FRPEFLNRFNGIVEFLHLDKDALQDIV----NLLLDDVQVTLDKK 634 Query 339 NVELEFEEEALSEIAKKAIERKTGARGLRSIIE 371 + ++ ++A + ++ + + GAR LR I+E Sbjct 635 GITMDVSQDAKDWLIEEGYDEELGARPLRRIVE 667 > tr|A2RIW9|A2RIW9_LACLM ATP-dependent Clp protease ATP-binding subunit OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=clpC PE=3 SV=1 Length=816 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 85/327 (26%), Positives = 142/327 (43%), Gaps = 70/327 (21%) Query 71 LNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA 130 L++ V+GQ++A +++ A+ + S V D + +GPTG GKT LA+ LA Sbjct 515 LHKRVVGQEEAISAVSRAIRR------ARSGVADSRRPMGSFMFLGPTGVGKTELAKALA 568 Query 131 -----------RILNVPFAIADATSL---TEAGYVGEDVENILLKLIQAADYDVEKAEKG 176 R+ F +TS GYVG D L + ++ Y V Sbjct 569 DSVFGSEDNMIRVDMSEFMEKHSTSRLIGAPPGYVGYDEGGQLTERVRNKPYSV------ 622 Query 177 IIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQID 236 + +DE++K + V +L+IL+ V GRK + I I Sbjct 623 -VLLDEVEK--------------AHLDVFNIMLQILDDGF--VTDTKGRKVDFRNTIIIM 665 Query 237 TTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIP 296 T+N+ GA K +GFGA N AD + S++L E L+ P Sbjct 666 TSNL-----GA--------TALRDDKTVGFGAKNITADYSA--MQSRILEE--LKRHYRP 708 Query 297 EFIGRLP---VIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 EF+ R+ V SLE + E +V I++K +L+K+ + ++ ++ A+ IA Sbjct 709 EFLNRIDENIVFHSLESQEIEQIVKIMSK---SLIKRLAE----QDIHVKLTPSAIKLIA 761 Query 354 KKAIERKTGARGLRSIIEGIMLDVMFE 380 + + + GAR LR ++ + D++ E Sbjct 762 EVGFDPEYGARPLRKALQKEVEDLLSE 788 > sp|Q6GJE4|CLPC_STAAR ATP-dependent Clp protease ATP-binding subunit ClpC OS=Staphylococcus aureus (strain MRSA252) GN=clpC PE=3 SV=1 Length=818 Score = 53.9 bits (128), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 85/329 (26%), Positives = 136/329 (41%), Gaps = 64/329 (19%) Query 67 IREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLA 126 + + L+E VIGQ A S++ AV + + + D + + +GPTG GKT LA Sbjct 502 LEDTLHERVIGQKDAVNSISKAVRR------ARAGLKDPKRPIGSFIFLGPTGVGKTELA 555 Query 127 QTLA-----------RILNVPFAIADATSL---TEAGYVGEDVENILLKLIQAADYDVEK 172 + LA R+ F A S GYVG D L + ++ Y V Sbjct 556 RALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSV-- 613 Query 173 AEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEF 232 I DEI+K +P V LL++L+ + GR + Sbjct 614 -----ILFDEIEKA-----HPD---------VFNILLQVLDD--GHLTDTKGRTVDFRNT 652 Query 233 IQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRF 292 I I T+N+ G +++ +R GFG + D E + +L E L+ Sbjct 653 IIIMTSNV---------GAQELQDQRFA----GFGGSSDGQDYET--IRKTMLKE--LKN 695 Query 293 GLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEI 352 PEF+ R+ I KL +E L I+T +V + L N+ + ++A +I Sbjct 696 SFRPEFLNRVDDIIVFHKLTKEELKEIVT----MMVNKLTNRLSEQNINIIVTDKAKDKI 751 Query 353 AKKAIERKTGARGLRSIIEGIMLDVMFEL 381 A++ + + GAR L I+ + D + EL Sbjct 752 AEEGYDPEYGARPLIRAIQKTIEDNLSEL 780 > tr|Q8Y8B1|Q8Y8B1_LISMO ATP-dependent protease OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=clpE PE=3 SV=1 Length=724 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 81/321 (25%), Positives = 132/321 (41%), Gaps = 74/321 (23%) Query 75 VIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLARILN 134 VIGQ+ A K +A A+ R+ SK + + +GPTG GKT L +TLAR L Sbjct 430 VIGQEDAVKKVAKAI--RRSRVGLKSKNRPI----GSFLFVGPTGVGKTELGRTLAREL- 482 Query 135 VPFAIADAT---SLTE--------------AGYVGEDVENILLKLIQAADYDVEKAEKGI 177 F ++A ++E GYVG + L + ++ Y I Sbjct 483 --FGTSEAMIRLDMSEFMEKHSISKLIGSPPGYVGHEEAGQLTEKVRRNPY-------SI 533 Query 178 IYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDT 237 I +DEI+K +P VQ L+ILE + GR ++ + I T Sbjct 534 ILLDEIEKA-----HPD---------VQHMFLQILED--GRLTDSQGRTVSFKDTVIIMT 577 Query 238 TNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIPE 297 +N GA D + +GF + + D+L+K L PE Sbjct 578 SN-----AGATD----------TEASVGFNTTTETKLEKGSDILAK------LGAYFKPE 616 Query 298 FIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAI 357 F+ RL + + L+++ LV I+ + ++ +ML + V ++ +E + Sbjct 617 FLNRLDSVIEFKSLEKDDLVQII----DLMLVDLNEMLAQEGVTIDVSKEVKEHLIDLGY 672 Query 358 ERKTGARGLRSIIEGIMLDVM 378 + K GAR LR I+ + D + Sbjct 673 DPKFGARPLRRTIQEHLEDTI 693 > sp|Q8CQ88|CLPC_STAES ATP-dependent Clp protease ATP-binding subunit ClpC OS=Staphylococcus epidermidis (strain ATCC 12228) GN=clpC PE=3 SV=1 Length=817 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 81/329 (25%), Positives = 140/329 (43%), Gaps = 64/329 (19%) Query 67 IREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLA 126 + + L++ VIGQ+ A S++ AV + + + D + + +GPTG GKT LA Sbjct 502 LEDTLHKRVIGQNDAVNSISKAVRR------ARAGLKDPKRPIGSFIFLGPTGVGKTELA 555 Query 127 QTLA-----------RILNVPFAIADATSL---TEAGYVGEDVENILLKLIQAADYDVEK 172 + LA R+ F A S GYVG D L + ++ Y V Sbjct 556 RALAESMFGEDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSV-- 613 Query 173 AEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEF 232 I DEI+K +P V LL++L+ + GR + Sbjct 614 -----ILFDEIEKA-----HPD---------VFNILLQVLDD--GHLTDTKGRTVDFRNT 652 Query 233 IQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRF 292 + I T+N+ G +++ +R GFG ++ +D E + K + ++ L+ Sbjct 653 VIIMTSNV---------GAQELQDQRFA----GFGGASEGSDYE---TVRKTMMKE-LKN 695 Query 293 GLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEI 352 PEF+ R+ I KL ++ L I+T +V + L N+ + ++A +I Sbjct 696 SFRPEFLNRVDDIIVFHKLTKDELKEIVT----MMVNKLTHRLSEQNINIVVTDKAKEKI 751 Query 353 AKKAIERKTGARGLRSIIEGIMLDVMFEL 381 A++ + + GAR L I+ + D + EL Sbjct 752 AEEGYDPEYGARPLIRAIQKTVEDNLSEL 780 > tr|Q8YAB6|Q8YAB6_LISMO Endopeptidase Clp ATP-binding chain C OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=clpC PE=3 SV=1 Length=820 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 87/339 (26%), Positives = 148/339 (44%), Gaps = 70/339 (21%) Query 67 IREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLA 126 + ++L+E VIGQD A K++++AV + + + D + + +GPTG GKT LA Sbjct 501 MEKLLHERVIGQDAAVKAVSLAVRR------ARAGLKDPKRPIGSFIFLGPTGVGKTELA 554 Query 127 QTLARILNVPFAIADAT---SLTE--------------AGYVGEDVENILLKLIQAADYD 169 + LA + F D+ ++E GYVG + L + ++ Y Sbjct 555 RALAESM---FGDEDSMIRIDMSEYMEKFSTARLVGAPPGYVGYEEGGQLTEKVRQKPYS 611 Query 170 VEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPH 229 V + +DEI+K +P + LL++L+ + GR Sbjct 612 V-------VLLDEIEKA-----HPDVF---------NMLLQVLDD--GRLTDSKGRVVDF 648 Query 230 QEFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDL 289 + + I T+NI GA Q +K+ K +GF + D + + +VL + Sbjct 649 RNTVIIMTSNI-----GA-----QEMKQ---DKSMGFNVTDPLKD--HKAMEHRVLQD-- 691 Query 290 LRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEAL 349 L+ PEFI R+ L E+ L I+T L Q K L ++ ++ E A Sbjct 692 LKQAFRPEFINRIDETIVFHSLQEKELKQIVT----LLTAQLTKRLAERDIHVKLTEGAK 747 Query 350 SEIAKKAIERKTGARGLRSIIEGIMLDVMFELPSRDDIE 388 S+IAK + + GAR L+ I+ + D++ E R +I+ Sbjct 748 SKIAKDGYDPEYGARPLKRAIQKEVEDMLSEELLRGNIK 786 > tr|Q1G869|Q1G869_LACDA ATP-dependent Clp protease, ATP-binding subunit OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpL PE=4 SV=1 Length=696 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 87/364 (24%), Positives = 143/364 (39%), Gaps = 87/364 (24%) Query 24 RKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKK 83 RK VA P +E T I ++G D+ + + + L +IGQD+A + Sbjct 369 RKTVATPADVAA--AVERLTGIPVSKMGAS------DIERLKGLSSRLKGKIIGQDEAVE 420 Query 84 SLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA--------RILNV 135 ++A A+ + + D+ + +GPTG GKT LA+ LA I+ + Sbjct 421 AVAKAIRRN------RAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIRL 474 Query 136 PFA-IADATSL-----TEAGYVG-EDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVAR 188 + +D T++ T AGYVG +D N L + ++ Y II +DEI+K Sbjct 475 DMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTEKVRRNPY-------SIILLDEIEKA-- 525 Query 189 KSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAF 248 +P + LL++L+ + G + I I T+N Sbjct 526 ---DPQVI---------TLLLQVLDD--GRLTDGQGNTVNFKNTIIIATSN--------- 562 Query 249 DGIEQIIKRRLGQKVIGFGADNKAADLEK-EDLLSKVLPEDLLRFGLIPEFIGRLPVIAS 307 GFG + D +K E L+ ++ P PEF+ R + Sbjct 563 ---------------AGFGNEQLMGDAKKDEKLMDRLAPY------FRPEFLNRFNAVIE 601 Query 308 LEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLR 367 L +E L I+ N ++ K L + L E A + ++ + GAR LR Sbjct 602 FSHLTKEDLKEIV----NLMLADVNKTLAKKGISLTVSESAKDYLIEQGYDEAMGARPLR 657 Query 368 SIIE 371 +IE Sbjct 658 RVIE 661 > tr|Q1G869|Q1G869_LACDA ATP-dependent Clp protease, ATP-binding subunit OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpL PE=4 SV=1 Length=696 Score = 50.4 bits (119), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 87/364 (24%), Positives = 143/364 (39%), Gaps = 87/364 (24%) Query 24 RKLVAGPGVYICDECIELCTEIVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKK 83 RK VA P +E T I ++G D+ + + + L +IGQD+A + Sbjct 369 RKTVATPADVAA--AVERLTGIPVSKMGAS------DIERLKGLSSRLKGKIIGQDEAVE 420 Query 84 SLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA--------RILNV 135 ++A A+ + + D+ + +GPTG GKT LA+ LA I+ + Sbjct 421 AVAKAIRRN------RAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIRL 474 Query 136 PFA-IADATSL-----TEAGYVG-EDVENILLKLIQAADYDVEKAEKGIIYIDEIDKVAR 188 + +D T++ T AGYVG +D N L + ++ Y II +DEI+K Sbjct 475 DMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTEKVRRNPY-------SIILLDEIEKA-- 525 Query 189 KSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQIDTTNILFICGGAF 248 +P + LL++L+ + G + I I T+N Sbjct 526 ---DPQVI---------TLLLQVLDD--GRLTDGQGNTVNFKNTIIIATSN--------- 562 Query 249 DGIEQIIKRRLGQKVIGFGADNKAADLEK-EDLLSKVLPEDLLRFGLIPEFIGRLPVIAS 307 GFG + D +K E L+ ++ P PEF+ R + Sbjct 563 ---------------AGFGNEQLMGDAKKDEKLMDRLAPY------FRPEFLNRFNAVIE 601 Query 308 LEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIAKKAIERKTGARGLR 367 L +E L I+ N ++ K L + L E A + ++ + GAR LR Sbjct 602 FSHLTKEDLKEIV----NLMLADVNKTLAKKGISLTVSESAKDYLIEQGYDEAMGARPLR 657 Query 368 SIIE 371 +IE Sbjct 658 RVIE 661 > tr|A0A0H2UNL3|A0A0H2UNL3_STRPN Putative ATP-dependent Clp protease, ATP-binding subunit OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=SP_0338 PE=4 SV=1 Length=701 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 77/333 (23%), Positives = 137/333 (41%), Gaps = 79/333 (24%) Query 55 EVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISL 114 ++E D+ + +++ L + VIGQD+A + +A A+ + + D+ N Sbjct 397 QMEASDIERLKDMAHRLQDKVIGQDKAVEVVARAIR------RNRAGFDEGNRPIGNFLF 450 Query 115 IGPTGSGKTLLAQTLA--------RILNVPFA-IADATSL-----TEAGYVG-EDVENIL 159 +G TG GKT LA+ LA I+ + + +D T++ T AGYVG +D N L Sbjct 451 VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTL 510 Query 160 LKLIQAADYDVEKAEKGIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASV 219 + ++ Y II +DEI+K +P + LL++L+ Sbjct 511 TERVRRNPY-------SIILLDEIEKA-----DPQVI---------TLLLQVLD------ 543 Query 220 PPQGGRKHPHQ-EFIQIDTTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKE 278 GR Q + T I+ F G+ A N D +K Sbjct 544 ---DGRLTDGQGNTVNFKNTVIIATSNAGF----------------GYEA-NLTEDADKP 583 Query 279 DLLSKVLPEDLLRFGLIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELD 338 +L+ ++ P R PEF+ R + L +E L I+ + ++ + + L Sbjct 584 ELMDRLKP--FFR----PEFLNRFNAVIEFSHLTKEDLSKIV----DLMLAEVNQTLAKK 633 Query 339 NVELEFEEEALSEIAKKAIERKTGARGLRSIIE 371 +++L + A I ++ + G R LR ++E Sbjct 634 DIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVE 666 > tr|J7MBF9|J7MBF9_STRP1 Negative regulator of genetic competence OS=Streptococcus pyogenes M1 476 GN=clpC PE=3 SV=1 Length=814 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 82/328 (25%), Positives = 137/328 (42%), Gaps = 70/328 (21%) Query 71 LNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA 130 L++ VIGQD A +++ A+ + I + + + +GPTG GKT LA+ LA Sbjct 514 LHKRVIGQDAAVTAISRAIRRNQSGIRTGKR------PIGSFMFLGPTGVGKTELAKALA 567 Query 131 RILN------VPFAIAD------ATSLTEA--GYVGEDVENILLKLIQAADYDVEKAEKG 176 +L + F +++ A+ L A GYVG D L + ++ Y V Sbjct 568 EVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSV------ 621 Query 177 IIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQID 236 + DE++K +P I LL++L+ + + GRK I I Sbjct 622 -LLFDEVEKA-----HPDIF---------NVLLQVLDDGI--LTDSRGRKVDFSNTIIIM 664 Query 237 TTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIP 296 T+N+ GA K +GFG + D + + ++L E LR P Sbjct 665 TSNL-----GA--------TALRDDKTVGFGVKDIHQD--HQAMEKRILEE--LRKTYRP 707 Query 297 EFIGRLP---VIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 EFI R+ V SL + + +V I+ +P L + L+ + AL ++ Sbjct 708 EFINRIDEKVVFHSLTQDNMRDVVKIMVQP-------LITTLAEKGITLKIQPLALKHLS 760 Query 354 KKAIERKTGARGLRSIIEGIMLDVMFEL 381 + + GAR LR ++ + D + EL Sbjct 761 EVGYDEHMGARPLRRTLQTEIEDKLSEL 788 > tr|Q99XR9|Q99XR9_STRP1 Putative endopeptidase Clp ATP-binding chain C OS=Streptococcus pyogenes serotype M1 GN=clpC PE=3 SV=1 Length=814 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 82/328 (25%), Positives = 137/328 (42%), Gaps = 70/328 (21%) Query 71 LNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTLA 130 L++ VIGQD A +++ A+ + I + + + +GPTG GKT LA+ LA Sbjct 514 LHKRVIGQDAAVTAISRAIRRNQSGIRTGKR------PIGSFMFLGPTGVGKTELAKALA 567 Query 131 RILN------VPFAIAD------ATSLTEA--GYVGEDVENILLKLIQAADYDVEKAEKG 176 +L + F +++ A+ L A GYVG D L + ++ Y V Sbjct 568 EVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSV------ 621 Query 177 IIYIDEIDKVARKSENPSITRDVSGEGVQQALLKILEGTVASVPPQGGRKHPHQEFIQID 236 + DE++K +P I LL++L+ + + GRK I I Sbjct 622 -LLFDEVEKA-----HPDIF---------NVLLQVLDDGI--LTDSRGRKVDFSNTIIIM 664 Query 237 TTNILFICGGAFDGIEQIIKRRLGQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFGLIP 296 T+N+ GA K +GFG + D + + ++L E LR P Sbjct 665 TSNL-----GA--------TALRDDKTVGFGVKDIHQD--HQAMEKRILEE--LRKTYRP 707 Query 297 EFIGRLP---VIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALSEIA 353 EFI R+ V SL + + +V I+ +P L + L+ + AL ++ Sbjct 708 EFINRIDEKVVFHSLTQDNMRDVVKIMVQP-------LITTLAEKGITLKIQPLALKHLS 760 Query 354 KKAIERKTGARGLRSIIEGIMLDVMFEL 381 + + GAR LR ++ + D + EL Sbjct 761 EVGYDEHMGARPLRRTLQTEIEDKLSEL 788 > tr|Q1GBM8|Q1GBM8_LACDA ATP-dependent Clp protease, ATP-binding subunit OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpC PE=4 SV=1 Length=819 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 87/321 (27%), Positives = 132/321 (41%), Gaps = 75/321 (23%) Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTL 129 IL+E VIGQD A K++A A+ S S + D + +GPTG GKT LA+ + Sbjct 509 ILHERVIGQDDAVKAVANAIRR------SRSGLKDENRPIGSFLFLGPTGVGKTELAKAV 562 Query 130 A--------RILNVPFA-IADATSLTE-----AGYVGEDVENILLKLIQAADYDVEKAEK 175 A I+ V + D S ++ GYVG + L ++ Y V Sbjct 563 AEAVFGSEDNIIRVDMSEYMDRESSSKLIGSAPGYVGYEEGGQLSNKVREHPYSV----- 617 Query 176 GIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKIL-EGTVASVPPQGGRKHPHQEFIQ 234 + DE++K NP I LL++L EG + GRK + I Sbjct 618 --VLFDEVEKA-----NPEIF---------NVLLRVLDEGFMTD---SLGRKVDFRNTII 658 Query 235 IDTTNILFICGGAFDGIEQIIKRRL-GQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFG 293 I T+N+ G+ R L +GF A +ED K++ E + R Sbjct 659 IMTSNL-----GS---------RSLEADSHVGFSA-------SQEDQ-GKLIAEKVTRAT 696 Query 294 ---LIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALS 350 PEF+ R+ + L+ + L I+T L ++ K L ++ L AL Sbjct 697 KDFFRPEFLNRIDEKIVFKPLEAKQLRKIVT----LLTRKLVKRLAEKDITLRLSPAALD 752 Query 351 EIAKKAIERKTGARGLRSIIE 371 ++AK + GAR LR I+ Sbjct 753 QLAKDGYNPEMGARPLRRTIQ 773 > tr|Q1GBM8|Q1GBM8_LACDA ATP-dependent Clp protease, ATP-binding subunit OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=clpC PE=4 SV=1 Length=819 Score = 45.4 bits (106), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 87/321 (27%), Positives = 132/321 (41%), Gaps = 75/321 (23%) Query 70 ILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDDVELSKSNISLIGPTGSGKTLLAQTL 129 IL+E VIGQD A K++A A+ S S + D + +GPTG GKT LA+ + Sbjct 509 ILHERVIGQDDAVKAVANAIRR------SRSGLKDENRPIGSFLFLGPTGVGKTELAKAV 562 Query 130 A--------RILNVPFA-IADATSLTE-----AGYVGEDVENILLKLIQAADYDVEKAEK 175 A I+ V + D S ++ GYVG + L ++ Y V Sbjct 563 AEAVFGSEDNIIRVDMSEYMDRESSSKLIGSAPGYVGYEEGGQLSNKVREHPYSV----- 617 Query 176 GIIYIDEIDKVARKSENPSITRDVSGEGVQQALLKIL-EGTVASVPPQGGRKHPHQEFIQ 234 + DE++K NP I LL++L EG + GRK + I Sbjct 618 --VLFDEVEKA-----NPEIF---------NVLLRVLDEGFMTD---SLGRKVDFRNTII 658 Query 235 IDTTNILFICGGAFDGIEQIIKRRL-GQKVIGFGADNKAADLEKEDLLSKVLPEDLLRFG 293 I T+N+ G+ R L +GF A +ED K++ E + R Sbjct 659 IMTSNL-----GS---------RSLEADSHVGFSA-------SQEDQ-GKLIAEKVTRAT 696 Query 294 ---LIPEFIGRLPVIASLEKLDEEALVAILTKPKNALVKQFKKMLELDNVELEFEEEALS 350 PEF+ R+ + L+ + L I+T L ++ K L ++ L AL Sbjct 697 KDFFRPEFLNRIDEKIVFKPLEAKQLRKIVT----LLTRKLVKRLAEKDITLRLSPAALD 752 Query 351 EIAKKAIERKTGARGLRSIIE 371 ++AK + GAR LR I+ Sbjct 753 QLAKDGYNPEMGARPLRRTIQ 773 > tr|J7M6I1|J7M6I1_STRP1 ATP-dependent zinc metalloprotease FtsH OS=Streptococcus pyogenes M1 476 GN=ftsH PE=3 SV=2 Length=659 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/77 (38%), Positives = 43/77 (56%), Gaps = 6/77 (8%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 + + L GP G+GKTLLA+ +A VPF + E +VG + +++ D Sbjct 221 AGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEM-FVG-----VGASRVRSLFED 274 Query 170 VEKAEKGIIYIDEIDKV 186 +KAE+ II+IDEID V Sbjct 275 AKKAERAIIFIDEIDAV 291 > tr|Q9A200|Q9A200_STRP1 ATP-dependent zinc metalloprotease FtsH OS=Streptococcus pyogenes serotype M1 GN=ftsH PE=3 SV=1 Length=659 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 29/77 (38%), Positives = 43/77 (56%), Gaps = 6/77 (8%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 + + L GP G+GKTLLA+ +A VPF + E +VG + +++ D Sbjct 221 AGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEM-FVG-----VGASRVRSLFED 274 Query 170 VEKAEKGIIYIDEIDKV 186 +KAE+ II+IDEID V Sbjct 275 AKKAERAIIFIDEIDAV 291 > sp|O69076|FTSH_STRPN ATP-dependent zinc metalloprotease FtsH OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) GN=ftsH PE=3 SV=3 Length=652 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 43/80 (54%), Gaps = 6/80 (8%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 + + L GP G+GKTLLA+ +A VPF + E +VG + +++ D Sbjct 221 AGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEM-FVG-----VGASRVRSLFED 274 Query 170 VEKAEKGIIYIDEIDKVARK 189 +KA II+IDEID V R+ Sbjct 275 AKKAAPAIIFIDEIDAVGRQ 294 > tr|Q1GBN8|Q1GBN8_LACDA ATP-dependent zinc metalloprotease FtsH OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=ftsH PE=3 SV=1 Length=737 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 S + L GP G+GKTLLA+ +A VPF + E +VG + A Sbjct 223 SGVLLEGPPGTGKTLLAKAVAGEAGVPFFYISGSDFVEM-FVGVGASRVRDLFTNA---- 277 Query 170 VEKAEKGIIYIDEIDKVARKSEN 192 +K II+IDEID + RK N Sbjct 278 -KKNAPSIIFIDEIDAIGRKRGN 299 > tr|Q1GBN8|Q1GBN8_LACDA ATP-dependent zinc metalloprotease FtsH OS=Lactobacillus delbrueckii subsp. bulgaricus (strain ATCC 11842 / DSM 20081 / JCM 1002 / NBRC 13953 / NCIMB 11778) GN=ftsH PE=3 SV=1 Length=737 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 40/83 (48%), Gaps = 6/83 (7%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 S + L GP G+GKTLLA+ +A VPF + E +VG + A Sbjct 223 SGVLLEGPPGTGKTLLAKAVAGEAGVPFFYISGSDFVEM-FVGVGASRVRDLFTNA---- 277 Query 170 VEKAEKGIIYIDEIDKVARKSEN 192 +K II+IDEID + RK N Sbjct 278 -KKNAPSIIFIDEIDAIGRKRGN 299 > sp|Q6GGZ9|Y1421_STAAR Uncharacterized protein SAR1421 OS=Staphylococcus aureus (strain MRSA252) GN=SAR1421 PE=3 SV=1 Length=263 Score = 42.0 bits (97), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/162 (33%), Positives = 77/162 (48%), Gaps = 44/162 (27%) Query 92 HYKRINSNSKVDD-----VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLT 146 HYK NS+S V + +L+K NI L GPTGSGKT LA+TL+ +++ P + + Sbjct 5 HYK--NSDSTVFNDAKALFDLNK-NILLKGPTGSGKTKLAETLSEVVDTPMHQVNCS--- 58 Query 147 EAGYVGEDVENIL-LKLIQA----------ADYDVEKA--EKGIIYIDEIDKVARKSENP 193 V D E++L K I+ D V KA E I+YIDEI+ +A+ P Sbjct 59 ----VDLDTESLLGFKTIKTNAEGQQEIVFVDGPVIKAMKEGHILYIDEIN-MAKPETLP 113 Query 194 ----------SITRDVSGEGVQ-----QALLKILEGTVASVP 220 IT +GE ++ + I EG V ++P Sbjct 114 VLNGVLDYRRQITNPYTGEVIKAVPGFNVIAAINEGYVGTLP 155 > tr|Q8YAC6|Q8YAC6_LISMO ATP-dependent zinc metalloprotease FtsH OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=ftsH PE=3 SV=1 Length=691 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 40/76 (53%), Gaps = 6/76 (8%) Query 114 LIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYDVEKA 173 L+GP G+GKTLLA+ +A VPF + E +VG + L + A +K Sbjct 218 LVGPPGTGKTLLARAVAGEAGVPFFSISGSDFVEM-FVGVGASRV-RDLFENA----KKN 271 Query 174 EKGIIYIDEIDKVARK 189 II+IDEID V R+ Sbjct 272 APCIIFIDEIDAVGRQ 287 > sp|Q8Y6Z8|RUVB_LISMO Holliday junction ATP-dependent DNA helicase RuvB OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=ruvB PE=3 SV=1 Length=335 Score = 40.8 bits (94), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 43/148 (29%), Positives = 65/148 (44%), Gaps = 31/148 (21%) Query 45 IVEEELGTEEEVEFKDVPKPQEIREILNEYVIGQDQAKKSLAVAVYNHYKRINSNSKVDD 104 I+ E EEV F+ +PQ L++Y IGQD+ K +L V + R N +D Sbjct 5 IISSETVDAEEVSFETSLRPQN----LSQY-IGQDKVKNNLTVFIEAATLR---NEALD- 55 Query 105 VELSKSNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQ 164 ++ L GP G GKT LA +A + ++ G D+ IL L Sbjct 56 ------HVLLYGPPGLGKTTLAMVIASEMGSQIKTTSGPAIERPG----DLATILTSL-- 103 Query 165 AADYDVEKAEKG-IIYIDEIDKVARKSE 191 E G +++IDEI +++R E Sbjct 104 ---------EPGDVLFIDEIHRLSRAIE 122 > tr|A2RH93|A2RH93_LACLM ATP-dependent zinc metalloprotease FtsH OS=Lactococcus lactis subsp. cremoris (strain MG1363) GN=ftsH PE=3 SV=1 Length=695 Score = 40.4 bits (93), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 41/80 (51%), Gaps = 6/80 (8%) Query 110 SNISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYD 169 + + L GP G+GKTLLA+ +A VPF + E +VG + L + A Sbjct 227 AGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEM-FVGVGASRV-RDLFENA--- 281 Query 170 VEKAEKGIIYIDEIDKVARK 189 +K II+IDEID V R+ Sbjct 282 -KKTAPSIIFIDEIDAVGRQ 300 > sp|Q8CP85|Y1092_STAES Uncharacterized protein SE_1092 OS=Staphylococcus epidermidis (strain ATCC 12228) GN=SE_1092 PE=3 SV=1 Length=263 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 44/138 (32%), Positives = 64/138 (46%), Gaps = 36/138 (26%) Query 111 NISLIGPTGSGKTLLAQTLARILNVPFAIADATSLTEAGYVGEDVENIL-LKLIQAA--- 166 NI L GPTGSGKT LA+TL+ ++ +P + + V D E++L K I Sbjct 26 NILLKGPTGSGKTKLAETLSNVMKLPMHQVNCS-------VDLDTESLLGFKTIHTNEEG 78 Query 167 -------DYDVEKA--EKGIIYIDEIDKVARKSENP----------SITRDVSGEGVQQA 207 D V KA E I+YIDEI+ +A+ P +T +GE ++ A Sbjct 79 HQEIVFIDGPVIKAMKEGHILYIDEIN-MAKPETLPILNGVLDYRRQLTNPYTGEVIKAA 137 Query 208 -----LLKILEGTVASVP 220 + I EG V ++P Sbjct 138 PGFNVIAAINEGYVGTLP 155 Lambda K H a alpha 0.315 0.136 0.374 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 1130510875 Database: all.fasta Posted date: Sep 5, 2017 3:11 PM Number of letters in database: 5,095,205 Number of sequences in database: 17,018 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40