data_2CV0
# 
_entry.id   2CV0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.279 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
PDB   2CV0         
NDB   PR0163       
RCSB  RCSB024650   
WWPDB D_1000024650 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.db_id 
_pdbx_database_related.details 
_pdbx_database_related.content_type 
PDB      1GLN           .                                                                                                
unspecified 
PDB      1G59           .                                                                                                
unspecified 
PDB      1J09           .                                                                                                
unspecified 
PDB      1N75           .                                                                                                
unspecified 
PDB      1N77           .                                                                                                
unspecified 
PDB      1N78           .                                                                                                
unspecified 
PDB      2CUZ           'the same protein complexed with L-glutamate'                                                    
unspecified 
PDB      2CV1           'the same protein complexed with tRNA(Glu), ATP, an analog of L-glutamate: a quaternary complex' 
unspecified 
PDB      2CV2           'the same protein complexed with tRNA(Glu), an enzyme inhibitor, Glu-AMS'                        
unspecified 
PDB      2DXI           .                                                                                                
unspecified 
TargetDB ttk003000897.8 .                                                                                                
unspecified 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.entry_id                        2CV0 
_pdbx_database_status.recvd_initial_deposition_date   2005-05-31 
_pdbx_database_status.deposit_site                    PDBJ 
_pdbx_database_status.process_site                    PDBJ 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.SG_entry                        Y 
_pdbx_database_status.pdb_format_compatible           Y 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.methods_development_category    ? 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
'Sekine, S.'                                             1 
'Yokoyama, S.'                                           2 
'RIKEN Structural Genomics/Proteomics Initiative (RSGI)' 3 
# 
_citation.id                        primary 
_citation.title                     
'Structural bases of transfer RNA-dependent amino acid recognition and activation by glutamyl-tRNA synthetase' 
_citation.journal_abbrev            Structure 
_citation.journal_volume            14 
_citation.page_first                1791 
_citation.page_last                 1799 
_citation.year                      2006 
_citation.journal_id_ASTM           STRUE6 
_citation.country                   UK 
_citation.journal_id_ISSN           0969-2126 
_citation.journal_id_CSD            2005 
_citation.book_publisher            ? 
_citation.pdbx_database_id_PubMed   17161369 
_citation.pdbx_database_id_DOI      10.1016/j.str.2006.10.005 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
primary 'Sekine, S.'    1 
primary 'Shichiri, M.'  2 
primary 'Bernier, S.'   3 
primary 'Chenevert, R.' 4 
primary 'Lapointe, J.'  5 
primary 'Yokoyama, S.'  6 
# 
_cell.entry_id           2CV0 
_cell.length_a           110.727 
_cell.length_b           219.321 
_cell.length_c           135.400 
_cell.angle_alpha        90.00 
_cell.angle_beta         90.00 
_cell.angle_gamma        90.00 
_cell.Z_PDB              16 
_cell.pdbx_unique_axis   ? 
_cell.length_a_esd       ? 
_cell.length_b_esd       ? 
_cell.length_c_esd       ? 
_cell.angle_alpha_esd    ? 
_cell.angle_beta_esd     ? 
_cell.angle_gamma_esd    ? 
# 
_symmetry.entry_id                         2CV0 
_symmetry.space_group_name_H-M             'C 2 2 21' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                20 
_symmetry.space_group_name_Hall            ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     syn tRNA                       24105.336 2   ?        ? ? ? 
2 polymer     man 'glutamyl-tRNA synthetase' 53988.727 2   6.1.1.17 ? ? ? 
3 non-polymer syn 'MAGNESIUM ION'            24.305    2   ?        ? ? ? 
4 non-polymer syn 'GLUTAMIC ACID'            147.129   2   ?        ? ? ? 
5 water       nat water                      18.015    281 ?        ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        'Glutamate--tRNA ligase, GluRS' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 polyribonucleotide no no GGCCCCAUCGUCUAGCGGUUAGGACGCGGCCCUCUCAAGGCCGAAACGGGGGUUCGAUUCCCCCUGGGGUCACCA 
GGCCCCAUCGUCUAGCGGUUAGGACGCGGCCCUCUCAAGGCCGAAACGGGGGUUCGAUUCCCCCUGGGGUCACCA C,D ?              
2 'polypeptide(L)'   no no 
;MVVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALKWLGLSYDEGPDVGGPHGPY
RQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIRKEKGGYDGRARNIPPEEAEERARRGEPHVIRLKVPRPGTTEVKD
ELRGVVVYDNQEIPDVVLLKSDGYPTYHLANVVDDHLMGVTDVIRAEEWLVSTPIHVLLYRAFGWEAPRFYHMPLLRNPD
KTKISKRKSHTSLDWYKAEGFLPEALRNYLCLMGFSMPDGREIFTLEEFIQAFTWERVSLGGPVFDLEKLRWMNGKYIRE
VLSLEEVAERVKPFLREAGLSWESEAYLRRAVELMRPRFDTLKEFPEKARYLFTEDYPVSEKAQRKLEEGLPLLKELYPR
LRAQEEWTEAALEALLRGFAAEKGVKLGQVAQPLRAALTGSLETPGLFEILALLGKERALRRLERALA
;
;MVVTRIAPSPTGDPHVGTAYIALFNYAWARRNGGRFIVRIEDTDRARYVPGAEERILAALKWLGLSYDEGPDVGGPHGPY
RQSERLPLYQKYAEELLKRGWAYRAFETPEELEQIRKEKGGYDGRARNIPPEEAEERARRGEPHVIRLKVPRPGTTEVKD
ELRGVVVYDNQEIPDVVLLKSDGYPTYHLANVVDDHLMGVTDVIRAEEWLVSTPIHVLLYRAFGWEAPRFYHMPLLRNPD
KTKISKRKSHTSLDWYKAEGFLPEALRNYLCLMGFSMPDGREIFTLEEFIQAFTWERVSLGGPVFDLEKLRWMNGKYIRE
VLSLEEVAERVKPFLREAGLSWESEAYLRRAVELMRPRFDTLKEFPEKARYLFTEDYPVSEKAQRKLEEGLPLLKELYPR
LRAQEEWTEAALEALLRGFAAEKGVKLGQVAQPLRAALTGSLETPGLFEILALLGKERALRRLERALA
;
A,B ttk003000897.8 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   G   n 
1 2   G   n 
1 3   C   n 
1 4   C   n 
1 5   C   n 
1 6   C   n 
1 7   A   n 
1 8   U   n 
1 9   C   n 
1 10  G   n 
1 11  U   n 
1 12  C   n 
1 13  U   n 
1 14  A   n 
1 15  G   n 
1 16  C   n 
1 17  G   n 
1 18  G   n 
1 19  U   n 
1 20  U   n 
1 21  A   n 
1 22  G   n 
1 23  G   n 
1 24  A   n 
1 25  C   n 
1 26  G   n 
1 27  C   n 
1 28  G   n 
1 29  G   n 
1 30  C   n 
1 31  C   n 
1 32  C   n 
1 33  U   n 
1 34  C   n 
1 35  U   n 
1 36  C   n 
1 37  A   n 
1 38  A   n 
1 39  G   n 
1 40  G   n 
1 41  C   n 
1 42  C   n 
1 43  G   n 
1 44  A   n 
1 45  A   n 
1 46  A   n 
1 47  C   n 
1 48  G   n 
1 49  G   n 
1 50  G   n 
1 51  G   n 
1 52  G   n 
1 53  U   n 
1 54  U   n 
1 55  C   n 
1 56  G   n 
1 57  A   n 
1 58  U   n 
1 59  U   n 
1 60  C   n 
1 61  C   n 
1 62  C   n 
1 63  C   n 
1 64  C   n 
1 65  U   n 
1 66  G   n 
1 67  G   n 
1 68  G   n 
1 69  G   n 
1 70  U   n 
1 71  C   n 
1 72  A   n 
1 73  C   n 
1 74  C   n 
1 75  A   n 
2 1   MET n 
2 2   VAL n 
2 3   VAL n 
2 4   THR n 
2 5   ARG n 
2 6   ILE n 
2 7   ALA n 
2 8   PRO n 
2 9   SER n 
2 10  PRO n 
2 11  THR n 
2 12  GLY n 
2 13  ASP n 
2 14  PRO n 
2 15  HIS n 
2 16  VAL n 
2 17  GLY n 
2 18  THR n 
2 19  ALA n 
2 20  TYR n 
2 21  ILE n 
2 22  ALA n 
2 23  LEU n 
2 24  PHE n 
2 25  ASN n 
2 26  TYR n 
2 27  ALA n 
2 28  TRP n 
2 29  ALA n 
2 30  ARG n 
2 31  ARG n 
2 32  ASN n 
2 33  GLY n 
2 34  GLY n 
2 35  ARG n 
2 36  PHE n 
2 37  ILE n 
2 38  VAL n 
2 39  ARG n 
2 40  ILE n 
2 41  GLU n 
2 42  ASP n 
2 43  THR n 
2 44  ASP n 
2 45  ARG n 
2 46  ALA n 
2 47  ARG n 
2 48  TYR n 
2 49  VAL n 
2 50  PRO n 
2 51  GLY n 
2 52  ALA n 
2 53  GLU n 
2 54  GLU n 
2 55  ARG n 
2 56  ILE n 
2 57  LEU n 
2 58  ALA n 
2 59  ALA n 
2 60  LEU n 
2 61  LYS n 
2 62  TRP n 
2 63  LEU n 
2 64  GLY n 
2 65  LEU n 
2 66  SER n 
2 67  TYR n 
2 68  ASP n 
2 69  GLU n 
2 70  GLY n 
2 71  PRO n 
2 72  ASP n 
2 73  VAL n 
2 74  GLY n 
2 75  GLY n 
2 76  PRO n 
2 77  HIS n 
2 78  GLY n 
2 79  PRO n 
2 80  TYR n 
2 81  ARG n 
2 82  GLN n 
2 83  SER n 
2 84  GLU n 
2 85  ARG n 
2 86  LEU n 
2 87  PRO n 
2 88  LEU n 
2 89  TYR n 
2 90  GLN n 
2 91  LYS n 
2 92  TYR n 
2 93  ALA n 
2 94  GLU n 
2 95  GLU n 
2 96  LEU n 
2 97  LEU n 
2 98  LYS n 
2 99  ARG n 
2 100 GLY n 
2 101 TRP n 
2 102 ALA n 
2 103 TYR n 
2 104 ARG n 
2 105 ALA n 
2 106 PHE n 
2 107 GLU n 
2 108 THR n 
2 109 PRO n 
2 110 GLU n 
2 111 GLU n 
2 112 LEU n 
2 113 GLU n 
2 114 GLN n 
2 115 ILE n 
2 116 ARG n 
2 117 LYS n 
2 118 GLU n 
2 119 LYS n 
2 120 GLY n 
2 121 GLY n 
2 122 TYR n 
2 123 ASP n 
2 124 GLY n 
2 125 ARG n 
2 126 ALA n 
2 127 ARG n 
2 128 ASN n 
2 129 ILE n 
2 130 PRO n 
2 131 PRO n 
2 132 GLU n 
2 133 GLU n 
2 134 ALA n 
2 135 GLU n 
2 136 GLU n 
2 137 ARG n 
2 138 ALA n 
2 139 ARG n 
2 140 ARG n 
2 141 GLY n 
2 142 GLU n 
2 143 PRO n 
2 144 HIS n 
2 145 VAL n 
2 146 ILE n 
2 147 ARG n 
2 148 LEU n 
2 149 LYS n 
2 150 VAL n 
2 151 PRO n 
2 152 ARG n 
2 153 PRO n 
2 154 GLY n 
2 155 THR n 
2 156 THR n 
2 157 GLU n 
2 158 VAL n 
2 159 LYS n 
2 160 ASP n 
2 161 GLU n 
2 162 LEU n 
2 163 ARG n 
2 164 GLY n 
2 165 VAL n 
2 166 VAL n 
2 167 VAL n 
2 168 TYR n 
2 169 ASP n 
2 170 ASN n 
2 171 GLN n 
2 172 GLU n 
2 173 ILE n 
2 174 PRO n 
2 175 ASP n 
2 176 VAL n 
2 177 VAL n 
2 178 LEU n 
2 179 LEU n 
2 180 LYS n 
2 181 SER n 
2 182 ASP n 
2 183 GLY n 
2 184 TYR n 
2 185 PRO n 
2 186 THR n 
2 187 TYR n 
2 188 HIS n 
2 189 LEU n 
2 190 ALA n 
2 191 ASN n 
2 192 VAL n 
2 193 VAL n 
2 194 ASP n 
2 195 ASP n 
2 196 HIS n 
2 197 LEU n 
2 198 MET n 
2 199 GLY n 
2 200 VAL n 
2 201 THR n 
2 202 ASP n 
2 203 VAL n 
2 204 ILE n 
2 205 ARG n 
2 206 ALA n 
2 207 GLU n 
2 208 GLU n 
2 209 TRP n 
2 210 LEU n 
2 211 VAL n 
2 212 SER n 
2 213 THR n 
2 214 PRO n 
2 215 ILE n 
2 216 HIS n 
2 217 VAL n 
2 218 LEU n 
2 219 LEU n 
2 220 TYR n 
2 221 ARG n 
2 222 ALA n 
2 223 PHE n 
2 224 GLY n 
2 225 TRP n 
2 226 GLU n 
2 227 ALA n 
2 228 PRO n 
2 229 ARG n 
2 230 PHE n 
2 231 TYR n 
2 232 HIS n 
2 233 MET n 
2 234 PRO n 
2 235 LEU n 
2 236 LEU n 
2 237 ARG n 
2 238 ASN n 
2 239 PRO n 
2 240 ASP n 
2 241 LYS n 
2 242 THR n 
2 243 LYS n 
2 244 ILE n 
2 245 SER n 
2 246 LYS n 
2 247 ARG n 
2 248 LYS n 
2 249 SER n 
2 250 HIS n 
2 251 THR n 
2 252 SER n 
2 253 LEU n 
2 254 ASP n 
2 255 TRP n 
2 256 TYR n 
2 257 LYS n 
2 258 ALA n 
2 259 GLU n 
2 260 GLY n 
2 261 PHE n 
2 262 LEU n 
2 263 PRO n 
2 264 GLU n 
2 265 ALA n 
2 266 LEU n 
2 267 ARG n 
2 268 ASN n 
2 269 TYR n 
2 270 LEU n 
2 271 CYS n 
2 272 LEU n 
2 273 MET n 
2 274 GLY n 
2 275 PHE n 
2 276 SER n 
2 277 MET n 
2 278 PRO n 
2 279 ASP n 
2 280 GLY n 
2 281 ARG n 
2 282 GLU n 
2 283 ILE n 
2 284 PHE n 
2 285 THR n 
2 286 LEU n 
2 287 GLU n 
2 288 GLU n 
2 289 PHE n 
2 290 ILE n 
2 291 GLN n 
2 292 ALA n 
2 293 PHE n 
2 294 THR n 
2 295 TRP n 
2 296 GLU n 
2 297 ARG n 
2 298 VAL n 
2 299 SER n 
2 300 LEU n 
2 301 GLY n 
2 302 GLY n 
2 303 PRO n 
2 304 VAL n 
2 305 PHE n 
2 306 ASP n 
2 307 LEU n 
2 308 GLU n 
2 309 LYS n 
2 310 LEU n 
2 311 ARG n 
2 312 TRP n 
2 313 MET n 
2 314 ASN n 
2 315 GLY n 
2 316 LYS n 
2 317 TYR n 
2 318 ILE n 
2 319 ARG n 
2 320 GLU n 
2 321 VAL n 
2 322 LEU n 
2 323 SER n 
2 324 LEU n 
2 325 GLU n 
2 326 GLU n 
2 327 VAL n 
2 328 ALA n 
2 329 GLU n 
2 330 ARG n 
2 331 VAL n 
2 332 LYS n 
2 333 PRO n 
2 334 PHE n 
2 335 LEU n 
2 336 ARG n 
2 337 GLU n 
2 338 ALA n 
2 339 GLY n 
2 340 LEU n 
2 341 SER n 
2 342 TRP n 
2 343 GLU n 
2 344 SER n 
2 345 GLU n 
2 346 ALA n 
2 347 TYR n 
2 348 LEU n 
2 349 ARG n 
2 350 ARG n 
2 351 ALA n 
2 352 VAL n 
2 353 GLU n 
2 354 LEU n 
2 355 MET n 
2 356 ARG n 
2 357 PRO n 
2 358 ARG n 
2 359 PHE n 
2 360 ASP n 
2 361 THR n 
2 362 LEU n 
2 363 LYS n 
2 364 GLU n 
2 365 PHE n 
2 366 PRO n 
2 367 GLU n 
2 368 LYS n 
2 369 ALA n 
2 370 ARG n 
2 371 TYR n 
2 372 LEU n 
2 373 PHE n 
2 374 THR n 
2 375 GLU n 
2 376 ASP n 
2 377 TYR n 
2 378 PRO n 
2 379 VAL n 
2 380 SER n 
2 381 GLU n 
2 382 LYS n 
2 383 ALA n 
2 384 GLN n 
2 385 ARG n 
2 386 LYS n 
2 387 LEU n 
2 388 GLU n 
2 389 GLU n 
2 390 GLY n 
2 391 LEU n 
2 392 PRO n 
2 393 LEU n 
2 394 LEU n 
2 395 LYS n 
2 396 GLU n 
2 397 LEU n 
2 398 TYR n 
2 399 PRO n 
2 400 ARG n 
2 401 LEU n 
2 402 ARG n 
2 403 ALA n 
2 404 GLN n 
2 405 GLU n 
2 406 GLU n 
2 407 TRP n 
2 408 THR n 
2 409 GLU n 
2 410 ALA n 
2 411 ALA n 
2 412 LEU n 
2 413 GLU n 
2 414 ALA n 
2 415 LEU n 
2 416 LEU n 
2 417 ARG n 
2 418 GLY n 
2 419 PHE n 
2 420 ALA n 
2 421 ALA n 
2 422 GLU n 
2 423 LYS n 
2 424 GLY n 
2 425 VAL n 
2 426 LYS n 
2 427 LEU n 
2 428 GLY n 
2 429 GLN n 
2 430 VAL n 
2 431 ALA n 
2 432 GLN n 
2 433 PRO n 
2 434 LEU n 
2 435 ARG n 
2 436 ALA n 
2 437 ALA n 
2 438 LEU n 
2 439 THR n 
2 440 GLY n 
2 441 SER n 
2 442 LEU n 
2 443 GLU n 
2 444 THR n 
2 445 PRO n 
2 446 GLY n 
2 447 LEU n 
2 448 PHE n 
2 449 GLU n 
2 450 ILE n 
2 451 LEU n 
2 452 ALA n 
2 453 LEU n 
2 454 LEU n 
2 455 GLY n 
2 456 LYS n 
2 457 GLU n 
2 458 ARG n 
2 459 ALA n 
2 460 LEU n 
2 461 ARG n 
2 462 ARG n 
2 463 LEU n 
2 464 GLU n 
2 465 ARG n 
2 466 ALA n 
2 467 LEU n 
2 468 ALA n 
# 
_entity_src_gen.entity_id                          2 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      ? 
_entity_src_gen.pdbx_beg_seq_num                   ? 
_entity_src_gen.pdbx_end_seq_num                   ? 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     Thermus 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Thermus thermophilus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     274 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli BL21(DE3)' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     469008 
_entity_src_gen.host_org_genus                     Escherichia 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   'Escherichia coli' 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               'BL21(DE3)' 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          plasmid 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       pK7 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              1 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       ? 
_pdbx_entity_src_syn.pdbx_end_seq_num       ? 
_pdbx_entity_src_syn.organism_scientific    ? 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       ? 
_pdbx_entity_src_syn.details                'In vitro transcription' 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.entity_id 
_struct_ref.pdbx_align_begin 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_db_isoform 
1 UNP SYE_THET8 P27000 2 1 ? ? 
2 PDB 2CV0      2CV0   1 ? ? ? 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 2CV0 A 1 ? 468 ? P27000 1   ? 468 ? 1   468 
2 1 2CV0 B 1 ? 468 ? P27000 1   ? 468 ? 1   468 
3 2 2CV0 C 1 ? 75  ? 2CV0   501 ? 576 ? 501 576 
4 2 2CV0 D 1 ? 75  ? 2CV0   501 ? 576 ? 501 576 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A   'RNA linking'       y "ADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
ALA 'L-peptide linking' y ALANINE                      ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                     ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                   ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'              ? 'C4 H7 N O4'      133.103 
C   'RNA linking'       y "CYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O8 P'  323.197 
CYS 'L-peptide linking' y CYSTEINE                     ? 'C3 H7 N O2 S'    121.158 
G   'RNA linking'       y "GUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O8 P' 363.221 
GLN 'L-peptide linking' y GLUTAMINE                    ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'              ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                      ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                    ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                        ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                   ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                      ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                       ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                   ? 'C5 H11 N O2 S'   149.211 
MG  non-polymer         . 'MAGNESIUM ION'              ? 'Mg 2'            24.305  
PHE 'L-peptide linking' y PHENYLALANINE                ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                      ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                       ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                    ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                   ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                     ? 'C9 H11 N O3'     181.189 
U   'RNA linking'       y "URIDINE-5'-MONOPHOSPHATE"   ? 'C9 H13 N2 O9 P'  324.181 
VAL 'L-peptide linking' y VALINE                       ? 'C5 H11 N O2'     117.146 
# 
_exptl.entry_id          2CV0 
_exptl.method            'X-RAY DIFFRACTION' 
_exptl.crystals_number   1 
# 
_exptl_crystal.id                    1 
_exptl_crystal.density_meas          ? 
_exptl_crystal.density_Matthews      2.61 
_exptl_crystal.density_percent_sol   52.94 
_exptl_crystal.description           ? 
_exptl_crystal.F_000                 ? 
_exptl_crystal.preparation           ? 
# 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, HANGING DROP' 
_exptl_crystal_grow.temp            293 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.pH              6.7 
_exptl_crystal_grow.pdbx_details    
'PEG1500, Mops-Na, ammonium sulfate, MPD, pH 6.7, VAPOR DIFFUSION, HANGING DROP, temperature 293K' 
_exptl_crystal_grow.pdbx_pH_range   . 
# 
loop_
_exptl_crystal_grow_comp.crystal_id 
_exptl_crystal_grow_comp.id 
_exptl_crystal_grow_comp.sol_id 
_exptl_crystal_grow_comp.name 
_exptl_crystal_grow_comp.volume 
_exptl_crystal_grow_comp.conc 
_exptl_crystal_grow_comp.details 
1 1 1 PEG1500            ? ? ? 
1 2 1 Mops-Na            ? ? ? 
1 3 1 'ammonium sulfate' ? ? ? 
1 4 1 MPD                ? ? ? 
1 5 1 HOH                ? ? ? 
1 6 2 PEG1500            ? ? ? 
1 7 2 'ammonium sulfate' ? ? ? 
1 8 2 MPD                ? ? ? 
1 9 2 HOH                ? ? ? 
# 
_diffrn.id                     1 
_diffrn.ambient_temp           100 
_diffrn.ambient_temp_details   ? 
_diffrn.crystal_id             1 
# 
_diffrn_detector.diffrn_id              1 
_diffrn_detector.detector               CCD 
_diffrn_detector.type                   'Bruker DIP-6040' 
_diffrn_detector.pdbx_collection_date   2004-03-04 
_diffrn_detector.details                ? 
# 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.monochromator                    silicon 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.9 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.diffrn_id                   1 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.type                        'SPRING-8 BEAMLINE BL44XU' 
_diffrn_source.pdbx_synchrotron_site       SPring-8 
_diffrn_source.pdbx_synchrotron_beamline   BL44XU 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_wavelength_list        0.9 
# 
_reflns.entry_id                     2CV0 
_reflns.observed_criterion_sigma_I   -3 
_reflns.observed_criterion_sigma_F   ? 
_reflns.d_resolution_low             50 
_reflns.d_resolution_high            2.35 
_reflns.number_obs                   67216 
_reflns.number_all                   67216 
_reflns.percent_possible_obs         96.9 
_reflns.pdbx_Rmerge_I_obs            0.098 
_reflns.pdbx_Rsym_value              0.098 
_reflns.pdbx_netI_over_sigmaI        14.5 
_reflns.B_iso_Wilson_estimate        36.4 
_reflns.pdbx_redundancy              4.4 
_reflns.R_free_details               ? 
_reflns.pdbx_chi_squared             ? 
_reflns.pdbx_scaling_rejects         ? 
_reflns.pdbx_diffrn_id               1 
_reflns.pdbx_ordinal                 1 
# 
_reflns_shell.d_res_high             2.35 
_reflns_shell.d_res_low              2.43 
_reflns_shell.percent_possible_all   98.3 
_reflns_shell.Rmerge_I_obs           ? 
_reflns_shell.pdbx_Rsym_value        ? 
_reflns_shell.meanI_over_sigI_obs    1.92 
_reflns_shell.pdbx_redundancy        ? 
_reflns_shell.percent_possible_obs   ? 
_reflns_shell.number_unique_all      ? 
_reflns_shell.number_measured_all    ? 
_reflns_shell.number_measured_obs    ? 
_reflns_shell.number_unique_obs      ? 
_reflns_shell.pdbx_chi_squared       ? 
_reflns_shell.pdbx_diffrn_id         ? 
_reflns_shell.pdbx_ordinal           1 
# 
_refine.entry_id                                 2CV0 
_refine.ls_number_reflns_obs                     62447 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          0.0 
_refine.pdbx_data_cutoff_high_absF               4042237.43 
_refine.pdbx_data_cutoff_low_absF                0.000000 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             19.96 
_refine.ls_d_res_high                            2.40 
_refine.ls_percent_reflns_obs                    96.9 
_refine.ls_R_factor_obs                          0.212 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       0.212 
_refine.ls_R_factor_R_free                       0.271 
_refine.ls_R_factor_R_free_error                 0.005 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 5.1 
_refine.ls_number_reflns_R_free                  3191 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               48.7 
_refine.aniso_B[1][1]                            8.03 
_refine.aniso_B[2][2]                            -7.73 
_refine.aniso_B[3][3]                            -0.31 
_refine.aniso_B[1][2]                            0.00 
_refine.aniso_B[1][3]                            0.00 
_refine.aniso_B[2][3]                            0.00 
_refine.solvent_model_details                    'FLAT MODEL' 
_refine.solvent_model_param_ksol                 0.252931 
_refine.solvent_model_param_bsol                 24.9552 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               THROUGHOUT 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_isotropic_thermal_model             RESTRAINED 
_refine.pdbx_stereochemistry_target_values       'Engh & Huber' 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            RANDOM 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_B                             ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.pdbx_diffrn_id                           1 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
_refine_analyze.entry_id                        2CV0 
_refine_analyze.Luzzati_coordinate_error_obs    0.29 
_refine_analyze.Luzzati_sigma_a_obs             0.32 
_refine_analyze.Luzzati_d_res_low_obs           5.00 
_refine_analyze.Luzzati_coordinate_error_free   0.39 
_refine_analyze.Luzzati_sigma_a_free            0.46 
_refine_analyze.Luzzati_d_res_low_free          ? 
_refine_analyze.number_disordered_residues      ? 
_refine_analyze.occupancy_sum_hydrogen          ? 
_refine_analyze.occupancy_sum_non_hydrogen      ? 
_refine_analyze.pdbx_refine_id                  'X-RAY DIFFRACTION' 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.pdbx_number_atoms_protein        7628 
_refine_hist.pdbx_number_atoms_nucleic_acid   3194 
_refine_hist.pdbx_number_atoms_ligand         22 
_refine_hist.number_atoms_solvent             281 
_refine_hist.number_atoms_total               11125 
_refine_hist.d_res_high                       2.40 
_refine_hist.d_res_low                        19.96 
# 
loop_
_refine_ls_restr.type 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.weight 
_refine_ls_restr.number 
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.pdbx_restraint_function 
c_bond_d                0.009 ?    ? ? 'X-RAY DIFFRACTION' ? 
c_bond_d_na             ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_bond_d_prot           ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_d               ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_d_na            ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_d_prot          ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_deg             1.5   ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_deg_na          ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_angle_deg_prot        ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_dihedral_angle_d      21.7  ?    ? ? 'X-RAY DIFFRACTION' ? 
c_dihedral_angle_d_na   ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_dihedral_angle_d_prot ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_improper_angle_d      1.55  ?    ? ? 'X-RAY DIFFRACTION' ? 
c_improper_angle_d_na   ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_improper_angle_d_prot ?     ?    ? ? 'X-RAY DIFFRACTION' ? 
c_mcbond_it             4.74  1.50 ? ? 'X-RAY DIFFRACTION' ? 
c_mcangle_it            6.15  2.00 ? ? 'X-RAY DIFFRACTION' ? 
c_scbond_it             6.62  2.00 ? ? 'X-RAY DIFFRACTION' ? 
c_scangle_it            8.22  2.50 ? ? 'X-RAY DIFFRACTION' ? 
# 
_refine_ls_shell.pdbx_total_number_of_bins_used   10 
_refine_ls_shell.d_res_high                       2.40 
_refine_ls_shell.d_res_low                        2.49 
_refine_ls_shell.number_reflns_R_work             5939 
_refine_ls_shell.R_factor_R_work                  0.302 
_refine_ls_shell.percent_reflns_obs               98.2 
_refine_ls_shell.R_factor_R_free                  0.396 
_refine_ls_shell.R_factor_R_free_error            0.023 
_refine_ls_shell.percent_reflns_R_free            4.9 
_refine_ls_shell.number_reflns_R_free             304 
_refine_ls_shell.redundancy_reflns_obs            ? 
_refine_ls_shell.number_reflns_all                ? 
_refine_ls_shell.number_reflns_obs                ? 
_refine_ls_shell.R_factor_all                     ? 
_refine_ls_shell.pdbx_refine_id                   'X-RAY DIFFRACTION' 
# 
loop_
_pdbx_xplor_file.serial_no 
_pdbx_xplor_file.param_file 
_pdbx_xplor_file.topol_file 
_pdbx_xplor_file.pdbx_refine_id 
1 protein_rep.param protein.top 'X-RAY DIFFRACTION' 
2 water_rep.param   water.top   'X-RAY DIFFRACTION' 
3 dna-rna_rep.param dna-rna.top 'X-RAY DIFFRACTION' 
4 ion.param         ion.top     'X-RAY DIFFRACTION' 
# 
_struct.entry_id                  2CV0 
_struct.title                     'Glutamyl-tRNA synthetase from Thermus thermophilus in complex with tRNA(Glu) and L-glutamate' 
_struct.pdbx_descriptor           'glutamyl-tRNA synthetase(E.C.6.1.1.17)/tRNA' 
_struct.pdbx_model_details        ? 
_struct.pdbx_CASP_flag            ? 
_struct.pdbx_model_type_details   ? 
# 
_struct_keywords.entry_id        2CV0 
_struct_keywords.pdbx_keywords   ligase/RNA 
_struct_keywords.text            
;ligase, RNA, Structural Genomics, NPPSFA, National Project on Protein Structural and Functional Analyses, RIKEN Structural Genomics/Proteomics Initiative, RSGI, ligase-RNA COMPLEX
;
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
I N N 5 ? 
J N N 5 ? 
K N N 5 ? 
L N N 5 ? 
# 
loop_
_struct_biol.id 
_struct_biol.details 
1 ? 
2 ? 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  1  HIS C 15  ? ASN C 32  ? HIS A 15  ASN A 32  1 ? 18 
HELX_P HELX_P2  2  GLY C 51  ? GLY C 64  ? GLY A 51  GLY A 64  1 ? 14 
HELX_P HELX_P3  3  ARG C 81  ? GLU C 84  ? ARG A 81  GLU A 84  5 ? 4  
HELX_P HELX_P4  4  ARG C 85  ? ARG C 99  ? ARG A 85  ARG A 99  1 ? 15 
HELX_P HELX_P5  5  THR C 108 ? GLY C 120 ? THR A 108 GLY A 120 1 ? 13 
HELX_P HELX_P6  6  GLY C 124 ? ILE C 129 ? GLY A 124 ILE A 129 5 ? 6  
HELX_P HELX_P7  7  PRO C 130 ? ARG C 140 ? PRO A 130 ARG A 140 1 ? 11 
HELX_P HELX_P8  8  GLN C 171 ? ILE C 173 ? GLN A 171 ILE A 173 5 ? 3  
HELX_P HELX_P9  9  THR C 186 ? MET C 198 ? THR A 186 MET A 198 1 ? 13 
HELX_P HELX_P10 10 GLU C 208 ? VAL C 211 ? GLU A 208 VAL A 211 5 ? 4  
HELX_P HELX_P11 11 SER C 212 ? GLY C 224 ? SER A 212 GLY A 224 1 ? 13 
HELX_P HELX_P12 12 SER C 252 ? GLU C 259 ? SER A 252 GLU A 259 1 ? 8  
HELX_P HELX_P13 13 LEU C 262 ? LEU C 272 ? LEU A 262 LEU A 272 1 ? 11 
HELX_P HELX_P14 14 THR C 285 ? PHE C 293 ? THR A 285 PHE A 293 1 ? 9  
HELX_P HELX_P15 15 THR C 294 ? VAL C 298 ? THR A 294 VAL A 298 5 ? 5  
HELX_P HELX_P16 16 ASP C 306 ? VAL C 321 ? ASP A 306 VAL A 321 1 ? 16 
HELX_P HELX_P17 17 SER C 323 ? ALA C 338 ? SER A 323 ALA A 338 1 ? 16 
HELX_P HELX_P18 18 SER C 344 ? ARG C 356 ? SER A 344 ARG A 356 1 ? 13 
HELX_P HELX_P19 19 PRO C 357 ? PHE C 359 ? PRO A 357 PHE A 359 5 ? 3  
HELX_P HELX_P20 20 LYS C 363 ? ALA C 369 ? LYS A 363 ALA A 369 1 ? 7  
HELX_P HELX_P21 21 ARG C 370 ? PHE C 373 ? ARG A 370 PHE A 373 5 ? 4  
HELX_P HELX_P22 22 SER C 380 ? GLN C 404 ? SER A 380 GLN A 404 1 ? 25 
HELX_P HELX_P23 23 THR C 408 ? LYS C 423 ? THR A 408 LYS A 423 1 ? 16 
HELX_P HELX_P24 24 LYS C 426 ? GLY C 440 ? LYS A 426 GLY A 440 1 ? 15 
HELX_P HELX_P25 25 GLY C 446 ? ALA C 468 ? GLY A 446 ALA A 468 1 ? 23 
HELX_P HELX_P26 26 HIS D 15  ? ASN D 32  ? HIS B 15  ASN B 32  1 ? 18 
HELX_P HELX_P27 27 GLY D 51  ? GLY D 64  ? GLY B 51  GLY B 64  1 ? 14 
HELX_P HELX_P28 28 ARG D 81  ? GLU D 84  ? ARG B 81  GLU B 84  5 ? 4  
HELX_P HELX_P29 29 ARG D 85  ? ARG D 99  ? ARG B 85  ARG B 99  1 ? 15 
HELX_P HELX_P30 30 THR D 108 ? GLY D 120 ? THR B 108 GLY B 120 1 ? 13 
HELX_P HELX_P31 31 GLY D 124 ? ILE D 129 ? GLY B 124 ILE B 129 5 ? 6  
HELX_P HELX_P32 32 PRO D 130 ? ARG D 140 ? PRO B 130 ARG B 140 1 ? 11 
HELX_P HELX_P33 33 GLN D 171 ? ILE D 173 ? GLN B 171 ILE B 173 5 ? 3  
HELX_P HELX_P34 34 THR D 186 ? MET D 198 ? THR B 186 MET B 198 1 ? 13 
HELX_P HELX_P35 35 GLU D 208 ? VAL D 211 ? GLU B 208 VAL B 211 5 ? 4  
HELX_P HELX_P36 36 SER D 212 ? GLY D 224 ? SER B 212 GLY B 224 1 ? 13 
HELX_P HELX_P37 37 SER D 252 ? GLU D 259 ? SER B 252 GLU B 259 1 ? 8  
HELX_P HELX_P38 38 LEU D 262 ? MET D 273 ? LEU B 262 MET B 273 1 ? 12 
HELX_P HELX_P39 39 THR D 285 ? PHE D 293 ? THR B 285 PHE B 293 1 ? 9  
HELX_P HELX_P40 40 THR D 294 ? VAL D 298 ? THR B 294 VAL B 298 5 ? 5  
HELX_P HELX_P41 41 ASP D 306 ? VAL D 321 ? ASP B 306 VAL B 321 1 ? 16 
HELX_P HELX_P42 42 SER D 323 ? ALA D 338 ? SER B 323 ALA B 338 1 ? 16 
HELX_P HELX_P43 43 SER D 344 ? ARG D 356 ? SER B 344 ARG B 356 1 ? 13 
HELX_P HELX_P44 44 PRO D 357 ? PHE D 359 ? PRO B 357 PHE B 359 5 ? 3  
HELX_P HELX_P45 45 LYS D 363 ? ALA D 369 ? LYS B 363 ALA B 369 1 ? 7  
HELX_P HELX_P46 46 ARG D 370 ? PHE D 373 ? ARG B 370 PHE B 373 5 ? 4  
HELX_P HELX_P47 47 SER D 380 ? ALA D 403 ? SER B 380 ALA B 403 1 ? 24 
HELX_P HELX_P48 48 THR D 408 ? LYS D 423 ? THR B 408 LYS B 423 1 ? 16 
HELX_P HELX_P49 49 LYS D 426 ? GLY D 440 ? LYS B 426 GLY B 440 1 ? 15 
HELX_P HELX_P50 50 GLY D 446 ? LEU D 454 ? GLY B 446 LEU B 454 1 ? 9  
HELX_P HELX_P51 51 GLY D 455 ? ALA D 468 ? GLY B 455 ALA B 468 1 ? 14 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
metalc1   metalc ? ? E MG .  MG ? ? ? 1_555 I HOH .  O  ? ? C MG 901 C HOH 1150 1_555 ? ? ? ? ? ? ?                       2.650 ? 
hydrog1   hydrog ? ? A G  1  N1 ? ? ? 1_555 A C   71 N3 ? ? C G  501 C C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog2   hydrog ? ? A G  1  N2 ? ? ? 1_555 A C   71 O2 ? ? C G  501 C C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog3   hydrog ? ? A G  1  O6 ? ? ? 1_555 A C   71 N4 ? ? C G  501 C C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog4   hydrog ? ? A G  2  N1 ? ? ? 1_555 A U   70 O2 ? ? C G  502 C U   571  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog5   hydrog ? ? A G  2  O6 ? ? ? 1_555 A U   70 N3 ? ? C G  502 C U   571  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog6   hydrog ? ? A C  3  N3 ? ? ? 1_555 A G   69 N1 ? ? C C  503 C G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog7   hydrog ? ? A C  3  N4 ? ? ? 1_555 A G   69 O6 ? ? C C  503 C G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog8   hydrog ? ? A C  3  O2 ? ? ? 1_555 A G   69 N2 ? ? C C  503 C G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog9   hydrog ? ? A C  4  N3 ? ? ? 1_555 A G   68 N1 ? ? C C  504 C G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog10  hydrog ? ? A C  4  N4 ? ? ? 1_555 A G   68 O6 ? ? C C  504 C G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog11  hydrog ? ? A C  4  O2 ? ? ? 1_555 A G   68 N2 ? ? C C  504 C G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog12  hydrog ? ? A C  5  N3 ? ? ? 1_555 A G   67 N1 ? ? C C  505 C G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog13  hydrog ? ? A C  5  N4 ? ? ? 1_555 A G   67 O6 ? ? C C  505 C G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog14  hydrog ? ? A C  5  O2 ? ? ? 1_555 A G   67 N2 ? ? C C  505 C G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog15  hydrog ? ? A C  6  N3 ? ? ? 1_555 A G   66 N1 ? ? C C  506 C G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog16  hydrog ? ? A C  6  N4 ? ? ? 1_555 A G   66 O6 ? ? C C  506 C G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog17  hydrog ? ? A C  6  O2 ? ? ? 1_555 A G   66 N2 ? ? C C  506 C G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog18  hydrog ? ? A A  7  N1 ? ? ? 1_555 A U   65 N3 ? ? C A  507 C U   566  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog19  hydrog ? ? A A  7  N6 ? ? ? 1_555 A U   65 O4 ? ? C A  507 C U   566  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog20  hydrog ? ? A U  8  N3 ? ? ? 1_555 A A   14 N7 ? ? C U  508 C A   514  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog21  hydrog ? ? A U  8  O2 ? ? ? 1_555 A A   14 N6 ? ? C U  508 C A   514  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog22  hydrog ? ? A C  9  N4 ? ? ? 1_555 A G   23 O6 ? ? C C  509 C G   523  1_555 ? ? ? ? ? ? 'C-G PAIR'              ?     ? 
hydrog23  hydrog ? ? A G  10 N1 ? ? ? 1_555 A C   25 N3 ? ? C G  510 C C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog24  hydrog ? ? A G  10 N2 ? ? ? 1_555 A C   25 O2 ? ? C G  510 C C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog25  hydrog ? ? A G  10 O6 ? ? ? 1_555 A C   25 N4 ? ? C G  510 C C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog26  hydrog ? ? A U  11 N3 ? ? ? 1_555 A A   24 N1 ? ? C U  511 C A   524  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog27  hydrog ? ? A U  11 O4 ? ? ? 1_555 A A   24 N6 ? ? C U  511 C A   524  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog28  hydrog ? ? A C  12 N3 ? ? ? 1_555 A G   23 N1 ? ? C C  512 C G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog29  hydrog ? ? A C  12 N4 ? ? ? 1_555 A G   23 O6 ? ? C C  512 C G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog30  hydrog ? ? A C  12 O2 ? ? ? 1_555 A G   23 N2 ? ? C C  512 C G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog31  hydrog ? ? A U  13 N3 ? ? ? 1_555 A G   22 O6 ? ? C U  513 C G   522  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog32  hydrog ? ? A U  13 O2 ? ? ? 1_555 A G   22 N1 ? ? C U  513 C G   522  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog33  hydrog ? ? A A  14 N6 ? ? ? 1_555 A A   21 N3 ? ? C A  514 C A   521  1_555 ? ? ? ? ? ? 'A-A MISPAIR'           ?     ? 
hydrog34  hydrog ? ? A G  15 N2 ? ? ? 1_555 A U   19 O4 ? ? C G  515 C U   520  1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ?     ? 
hydrog35  hydrog ? ? A G  15 N1 ? ? ? 1_555 A C   47 O2 ? ? C G  515 C C   548  1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ?     ? 
hydrog36  hydrog ? ? A G  15 N2 ? ? ? 1_555 A C   47 N3 ? ? C G  515 C C   548  1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ?     ? 
hydrog37  hydrog ? ? A G  17 N1 ? ? ? 1_555 A U   54 O2 ? ? C G  518 C U   555  1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ?     ? 
hydrog38  hydrog ? ? A G  18 N1 ? ? ? 1_555 A C   55 N3 ? ? C G  519 C C   556  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog39  hydrog ? ? A G  18 N2 ? ? ? 1_555 A C   55 O2 ? ? C G  519 C C   556  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog40  hydrog ? ? A G  18 O6 ? ? ? 1_555 A C   55 N4 ? ? C G  519 C C   556  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog41  hydrog ? ? A U  19 O4 ? ? ? 1_555 A C   47 N4 ? ? C U  520 C C   548  1_555 ? ? ? ? ? ? 'U-C MISPAIR'           ?     ? 
hydrog42  hydrog ? ? A G  22 N7 ? ? ? 1_555 A A   46 N6 ? ? C G  522 C A   546  1_555 ? ? ? ? ? ? 'G-A MISPAIR'           ?     ? 
hydrog43  hydrog ? ? A G  26 N1 ? ? ? 1_555 A A   44 N1 ? ? C G  526 C A   544  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ?     ? 
hydrog44  hydrog ? ? A G  26 O6 ? ? ? 1_555 A A   44 N6 ? ? C G  526 C A   544  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ?     ? 
hydrog45  hydrog ? ? A C  27 N3 ? ? ? 1_555 A G   43 N1 ? ? C C  527 C G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog46  hydrog ? ? A C  27 N4 ? ? ? 1_555 A G   43 O6 ? ? C C  527 C G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog47  hydrog ? ? A C  27 O2 ? ? ? 1_555 A G   43 N2 ? ? C C  527 C G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog48  hydrog ? ? A G  28 N1 ? ? ? 1_555 A C   42 N3 ? ? C G  528 C C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog49  hydrog ? ? A G  28 N2 ? ? ? 1_555 A C   42 O2 ? ? C G  528 C C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog50  hydrog ? ? A G  28 O6 ? ? ? 1_555 A C   42 N4 ? ? C G  528 C C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog51  hydrog ? ? A G  29 N1 ? ? ? 1_555 A C   41 N3 ? ? C G  529 C C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog52  hydrog ? ? A G  29 N2 ? ? ? 1_555 A C   41 O2 ? ? C G  529 C C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog53  hydrog ? ? A G  29 O6 ? ? ? 1_555 A C   41 N4 ? ? C G  529 C C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog54  hydrog ? ? A C  30 N3 ? ? ? 1_555 A G   40 N1 ? ? C C  530 C G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog55  hydrog ? ? A C  30 N4 ? ? ? 1_555 A G   40 O6 ? ? C C  530 C G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog56  hydrog ? ? A C  30 O2 ? ? ? 1_555 A G   40 N2 ? ? C C  530 C G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog57  hydrog ? ? A C  31 N3 ? ? ? 1_555 A G   39 N1 ? ? C C  531 C G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog58  hydrog ? ? A C  31 N4 ? ? ? 1_555 A G   39 O6 ? ? C C  531 C G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog59  hydrog ? ? A C  31 O2 ? ? ? 1_555 A G   39 N2 ? ? C C  531 C G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog60  hydrog ? ? A C  32 O2 ? ? ? 1_555 A A   38 N6 ? ? C C  532 C A   538  1_555 ? ? ? ? ? ? 'C-A MISPAIR'           ?     ? 
hydrog61  hydrog ? ? A G  48 N1 ? ? ? 1_555 A C   64 N3 ? ? C G  549 C C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog62  hydrog ? ? A G  48 N2 ? ? ? 1_555 A C   64 O2 ? ? C G  549 C C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog63  hydrog ? ? A G  48 O6 ? ? ? 1_555 A C   64 N4 ? ? C G  549 C C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog64  hydrog ? ? A G  49 N1 ? ? ? 1_555 A C   63 N3 ? ? C G  550 C C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog65  hydrog ? ? A G  49 N2 ? ? ? 1_555 A C   63 O2 ? ? C G  550 C C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog66  hydrog ? ? A G  49 O6 ? ? ? 1_555 A C   63 N4 ? ? C G  550 C C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog67  hydrog ? ? A G  50 N1 ? ? ? 1_555 A C   62 N3 ? ? C G  551 C C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog68  hydrog ? ? A G  50 N2 ? ? ? 1_555 A C   62 O2 ? ? C G  551 C C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog69  hydrog ? ? A G  50 O6 ? ? ? 1_555 A C   62 N4 ? ? C G  551 C C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog70  hydrog ? ? A G  51 N1 ? ? ? 1_555 A C   61 N3 ? ? C G  552 C C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog71  hydrog ? ? A G  51 N2 ? ? ? 1_555 A C   61 O2 ? ? C G  552 C C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog72  hydrog ? ? A G  51 O6 ? ? ? 1_555 A C   61 N4 ? ? C G  552 C C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog73  hydrog ? ? A G  52 N1 ? ? ? 1_555 A C   60 N3 ? ? C G  553 C C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog74  hydrog ? ? A G  52 N2 ? ? ? 1_555 A C   60 O2 ? ? C G  553 C C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog75  hydrog ? ? A G  52 O6 ? ? ? 1_555 A C   60 N4 ? ? C G  553 C C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog76  hydrog ? ? A U  53 N3 ? ? ? 1_555 A A   57 N7 ? ? C U  554 C A   558  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog77  hydrog ? ? A U  53 O2 ? ? ? 1_555 A A   57 N6 ? ? C U  554 C A   558  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog78  hydrog ? ? B G  1  N1 ? ? ? 1_555 B C   71 N3 ? ? D G  501 D C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog79  hydrog ? ? B G  1  N2 ? ? ? 1_555 B C   71 O2 ? ? D G  501 D C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog80  hydrog ? ? B G  1  O6 ? ? ? 1_555 B C   71 N4 ? ? D G  501 D C   572  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog81  hydrog ? ? B G  2  N1 ? ? ? 1_555 B U   70 O2 ? ? D G  502 D U   571  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog82  hydrog ? ? B G  2  O6 ? ? ? 1_555 B U   70 N3 ? ? D G  502 D U   571  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog83  hydrog ? ? B C  3  N3 ? ? ? 1_555 B G   69 N1 ? ? D C  503 D G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog84  hydrog ? ? B C  3  N4 ? ? ? 1_555 B G   69 O6 ? ? D C  503 D G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog85  hydrog ? ? B C  3  O2 ? ? ? 1_555 B G   69 N2 ? ? D C  503 D G   570  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog86  hydrog ? ? B C  4  N3 ? ? ? 1_555 B G   68 N1 ? ? D C  504 D G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog87  hydrog ? ? B C  4  N4 ? ? ? 1_555 B G   68 O6 ? ? D C  504 D G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog88  hydrog ? ? B C  4  O2 ? ? ? 1_555 B G   68 N2 ? ? D C  504 D G   569  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog89  hydrog ? ? B C  5  N3 ? ? ? 1_555 B G   67 N1 ? ? D C  505 D G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog90  hydrog ? ? B C  5  N4 ? ? ? 1_555 B G   67 O6 ? ? D C  505 D G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog91  hydrog ? ? B C  5  O2 ? ? ? 1_555 B G   67 N2 ? ? D C  505 D G   568  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog92  hydrog ? ? B C  6  N3 ? ? ? 1_555 B G   66 N1 ? ? D C  506 D G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog93  hydrog ? ? B C  6  N4 ? ? ? 1_555 B G   66 O6 ? ? D C  506 D G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog94  hydrog ? ? B C  6  O2 ? ? ? 1_555 B G   66 N2 ? ? D C  506 D G   567  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog95  hydrog ? ? B A  7  N1 ? ? ? 1_555 B U   65 N3 ? ? D A  507 D U   566  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog96  hydrog ? ? B A  7  N6 ? ? ? 1_555 B U   65 O4 ? ? D A  507 D U   566  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog97  hydrog ? ? B U  8  N3 ? ? ? 1_555 B A   14 N7 ? ? D U  508 D A   514  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog98  hydrog ? ? B U  8  O2 ? ? ? 1_555 B A   14 N6 ? ? D U  508 D A   514  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog99  hydrog ? ? B C  9  N4 ? ? ? 1_555 B G   23 N7 ? ? D C  509 D G   523  1_555 ? ? ? ? ? ? 'C-G PAIR'              ?     ? 
hydrog100 hydrog ? ? B G  10 N1 ? ? ? 1_555 B C   25 N3 ? ? D G  510 D C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog101 hydrog ? ? B G  10 N2 ? ? ? 1_555 B C   25 O2 ? ? D G  510 D C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog102 hydrog ? ? B G  10 O6 ? ? ? 1_555 B C   25 N4 ? ? D G  510 D C   525  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog103 hydrog ? ? B U  11 N3 ? ? ? 1_555 B A   24 N1 ? ? D U  511 D A   524  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog104 hydrog ? ? B U  11 O4 ? ? ? 1_555 B A   24 N6 ? ? D U  511 D A   524  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog105 hydrog ? ? B C  12 N3 ? ? ? 1_555 B G   23 N1 ? ? D C  512 D G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog106 hydrog ? ? B C  12 N4 ? ? ? 1_555 B G   23 O6 ? ? D C  512 D G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog107 hydrog ? ? B C  12 O2 ? ? ? 1_555 B G   23 N2 ? ? D C  512 D G   523  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog108 hydrog ? ? B U  13 N3 ? ? ? 1_555 B G   22 O6 ? ? D U  513 D G   522  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog109 hydrog ? ? B U  13 O2 ? ? ? 1_555 B G   22 N1 ? ? D U  513 D G   522  1_555 ? ? ? ? ? ? TYPE_28_PAIR            ?     ? 
hydrog110 hydrog ? ? B A  14 N6 ? ? ? 1_555 B A   21 N3 ? ? D A  514 D A   521  1_555 ? ? ? ? ? ? 'A-A MISPAIR'           ?     ? 
hydrog111 hydrog ? ? B G  15 N2 ? ? ? 1_555 B U   19 O4 ? ? D G  515 D U   520  1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ?     ? 
hydrog112 hydrog ? ? B G  15 N1 ? ? ? 1_555 B C   47 O2 ? ? D G  515 D C   548  1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ?     ? 
hydrog113 hydrog ? ? B G  15 N2 ? ? ? 1_555 B C   47 N3 ? ? D G  515 D C   548  1_555 ? ? ? ? ? ? 'REVERSED WATSON-CRICK' ?     ? 
hydrog114 hydrog ? ? B G  17 N1 ? ? ? 1_555 B U   54 O2 ? ? D G  518 D U   555  1_555 ? ? ? ? ? ? 'G-U MISPAIR'           ?     ? 
hydrog115 hydrog ? ? B G  18 N1 ? ? ? 1_555 B C   55 N3 ? ? D G  519 D C   556  1_555 ? ? ? ? ? ? 'G-C PAIR'              ?     ? 
hydrog116 hydrog ? ? B U  19 O4 ? ? ? 1_555 B C   47 N4 ? ? D U  520 D C   548  1_555 ? ? ? ? ? ? 'U-C MISPAIR'           ?     ? 
hydrog117 hydrog ? ? B G  22 N7 ? ? ? 1_555 B A   46 N6 ? ? D G  522 D A   546  1_555 ? ? ? ? ? ? 'G-A MISPAIR'           ?     ? 
hydrog118 hydrog ? ? B G  26 N1 ? ? ? 1_555 B A   44 N1 ? ? D G  526 D A   544  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ?     ? 
hydrog119 hydrog ? ? B G  26 O6 ? ? ? 1_555 B A   44 N6 ? ? D G  526 D A   544  1_555 ? ? ? ? ? ? TYPE_8_PAIR             ?     ? 
hydrog120 hydrog ? ? B C  27 N3 ? ? ? 1_555 B G   43 N1 ? ? D C  527 D G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog121 hydrog ? ? B C  27 N4 ? ? ? 1_555 B G   43 O6 ? ? D C  527 D G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog122 hydrog ? ? B C  27 O2 ? ? ? 1_555 B G   43 N2 ? ? D C  527 D G   543  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog123 hydrog ? ? B G  28 N1 ? ? ? 1_555 B C   42 N3 ? ? D G  528 D C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog124 hydrog ? ? B G  28 N2 ? ? ? 1_555 B C   42 O2 ? ? D G  528 D C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog125 hydrog ? ? B G  28 O6 ? ? ? 1_555 B C   42 N4 ? ? D G  528 D C   542  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog126 hydrog ? ? B G  29 N1 ? ? ? 1_555 B C   41 N3 ? ? D G  529 D C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog127 hydrog ? ? B G  29 N2 ? ? ? 1_555 B C   41 O2 ? ? D G  529 D C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog128 hydrog ? ? B G  29 O6 ? ? ? 1_555 B C   41 N4 ? ? D G  529 D C   541  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog129 hydrog ? ? B C  30 N3 ? ? ? 1_555 B G   40 N1 ? ? D C  530 D G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog130 hydrog ? ? B C  30 N4 ? ? ? 1_555 B G   40 O6 ? ? D C  530 D G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog131 hydrog ? ? B C  30 O2 ? ? ? 1_555 B G   40 N2 ? ? D C  530 D G   540  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog132 hydrog ? ? B C  31 N3 ? ? ? 1_555 B G   39 N1 ? ? D C  531 D G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog133 hydrog ? ? B C  31 N4 ? ? ? 1_555 B G   39 O6 ? ? D C  531 D G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog134 hydrog ? ? B C  31 O2 ? ? ? 1_555 B G   39 N2 ? ? D C  531 D G   539  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog135 hydrog ? ? B C  32 O2 ? ? ? 1_555 B A   38 N6 ? ? D C  532 D A   538  1_555 ? ? ? ? ? ? 'C-A MISPAIR'           ?     ? 
hydrog136 hydrog ? ? B G  48 N1 ? ? ? 1_555 B C   64 N3 ? ? D G  549 D C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog137 hydrog ? ? B G  48 N2 ? ? ? 1_555 B C   64 O2 ? ? D G  549 D C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog138 hydrog ? ? B G  48 O6 ? ? ? 1_555 B C   64 N4 ? ? D G  549 D C   565  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog139 hydrog ? ? B G  49 N1 ? ? ? 1_555 B C   63 N3 ? ? D G  550 D C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog140 hydrog ? ? B G  49 N2 ? ? ? 1_555 B C   63 O2 ? ? D G  550 D C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog141 hydrog ? ? B G  49 O6 ? ? ? 1_555 B C   63 N4 ? ? D G  550 D C   564  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog142 hydrog ? ? B G  50 N1 ? ? ? 1_555 B C   62 N3 ? ? D G  551 D C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog143 hydrog ? ? B G  50 N2 ? ? ? 1_555 B C   62 O2 ? ? D G  551 D C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog144 hydrog ? ? B G  50 O6 ? ? ? 1_555 B C   62 N4 ? ? D G  551 D C   563  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog145 hydrog ? ? B G  51 N1 ? ? ? 1_555 B C   61 N3 ? ? D G  552 D C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog146 hydrog ? ? B G  51 N2 ? ? ? 1_555 B C   61 O2 ? ? D G  552 D C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog147 hydrog ? ? B G  51 O6 ? ? ? 1_555 B C   61 N4 ? ? D G  552 D C   562  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog148 hydrog ? ? B G  52 N1 ? ? ? 1_555 B C   60 N3 ? ? D G  553 D C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog149 hydrog ? ? B G  52 N2 ? ? ? 1_555 B C   60 O2 ? ? D G  553 D C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog150 hydrog ? ? B G  52 O6 ? ? ? 1_555 B C   60 N4 ? ? D G  553 D C   561  1_555 ? ? ? ? ? ? WATSON-CRICK            ?     ? 
hydrog151 hydrog ? ? B U  53 N3 ? ? ? 1_555 B A   57 N7 ? ? D U  554 D A   558  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
hydrog152 hydrog ? ? B U  53 O2 ? ? ? 1_555 B A   57 N6 ? ? D U  554 D A   558  1_555 ? ? ? ? ? ? 'REVERSED HOOGSTEEN'    ?     ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 GLY 78  C . ? GLY 78  A PRO 79  C ? PRO 79  A 1 0.52  
2 ARG 152 C . ? ARG 152 A PRO 153 C ? PRO 153 A 1 -0.02 
3 GLY 78  D . ? GLY 78  B PRO 79  D ? PRO 79  B 1 -0.77 
4 ARG 152 D . ? ARG 152 B PRO 153 D ? PRO 153 B 1 -0.71 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
A ? 2 ? 
B ? 3 ? 
C ? 2 ? 
D ? 2 ? 
E ? 2 ? 
F ? 3 ? 
G ? 2 ? 
H ? 2 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
A 1 2 ? parallel      
B 1 2 ? anti-parallel 
B 2 3 ? anti-parallel 
C 1 2 ? anti-parallel 
D 1 2 ? parallel      
E 1 2 ? parallel      
F 1 2 ? anti-parallel 
F 2 3 ? anti-parallel 
G 1 2 ? anti-parallel 
H 1 2 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
A 1 VAL C 3   ? ILE C 6   ? VAL A 3   ILE A 6   
A 2 ARG C 35  ? VAL C 38  ? ARG A 35  VAL A 38  
B 1 ALA C 102 ? ALA C 105 ? ALA A 102 ALA A 105 
B 2 VAL C 145 ? LEU C 148 ? VAL A 145 LEU A 148 
B 3 VAL C 177 ? LEU C 179 ? VAL A 177 LEU A 179 
C 1 THR C 155 ? ASP C 160 ? THR A 155 ASP A 160 
C 2 GLY C 164 ? ASP C 169 ? GLY A 164 ASP A 169 
D 1 ASP C 202 ? ALA C 206 ? ASP A 202 ALA A 206 
D 2 ARG C 229 ? MET C 233 ? ARG A 229 MET A 233 
E 1 VAL D 3   ? ILE D 6   ? VAL B 3   ILE B 6   
E 2 ARG D 35  ? VAL D 38  ? ARG B 35  VAL B 38  
F 1 ALA D 102 ? ALA D 105 ? ALA B 102 ALA B 105 
F 2 VAL D 145 ? LEU D 148 ? VAL B 145 LEU B 148 
F 3 VAL D 177 ? LEU D 179 ? VAL B 177 LEU B 179 
G 1 THR D 155 ? ASP D 160 ? THR B 155 ASP B 160 
G 2 GLY D 164 ? ASP D 169 ? GLY B 164 ASP B 169 
H 1 ASP D 202 ? ALA D 206 ? ASP B 202 ALA B 206 
H 2 ARG D 229 ? MET D 233 ? ARG B 229 MET B 233 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
A 1 2 N THR C 4   ? N THR A 4   O ARG C 35  ? O ARG A 35  
B 1 2 N TYR C 103 ? N TYR A 103 O ARG C 147 ? O ARG A 147 
B 2 3 N ILE C 146 ? N ILE A 146 O LEU C 178 ? O LEU A 178 
C 1 2 N VAL C 158 ? N VAL A 158 O VAL C 166 ? O VAL A 166 
D 1 2 N ARG C 205 ? N ARG A 205 O MET C 233 ? O MET A 233 
E 1 2 N THR D 4   ? N THR B 4   O ARG D 35  ? O ARG B 35  
F 1 2 N TYR D 103 ? N TYR B 103 O ARG D 147 ? O ARG B 147 
F 2 3 N ILE D 146 ? N ILE B 146 O LEU D 178 ? O LEU B 178 
G 1 2 N VAL D 158 ? N VAL B 158 O VAL D 166 ? O VAL B 166 
H 1 2 N ARG D 205 ? N ARG B 205 O MET D 233 ? O MET B 233 
# 
loop_
_struct_site.id 
_struct_site.pdbx_evidence_code 
_struct_site.pdbx_auth_asym_id 
_struct_site.pdbx_auth_comp_id 
_struct_site.pdbx_auth_seq_id 
_struct_site.pdbx_auth_ins_code 
_struct_site.pdbx_num_residues 
_struct_site.details 
AC1 Software ? ? ? ? 4 'BINDING SITE FOR RESIDUE MG C 901'  
AC2 Software ? ? ? ? 3 'BINDING SITE FOR RESIDUE MG D 902'  
AC3 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE GLU A 601' 
AC4 Software ? ? ? ? 9 'BINDING SITE FOR RESIDUE GLU A 602' 
# 
loop_
_struct_site_gen.id 
_struct_site_gen.site_id 
_struct_site_gen.pdbx_num_res 
_struct_site_gen.label_comp_id 
_struct_site_gen.label_asym_id 
_struct_site_gen.label_seq_id 
_struct_site_gen.pdbx_auth_ins_code 
_struct_site_gen.auth_comp_id 
_struct_site_gen.auth_asym_id 
_struct_site_gen.auth_seq_id 
_struct_site_gen.label_atom_id 
_struct_site_gen.label_alt_id 
_struct_site_gen.symmetry 
_struct_site_gen.details 
1  AC1 4 C   A 9   ? C   C 509  . ? 1_555 ? 
2  AC1 4 A   A 45  ? A   C 545  . ? 1_555 ? 
3  AC1 4 A   A 46  ? A   C 546  . ? 1_555 ? 
4  AC1 4 HOH I .   ? HOH C 1150 . ? 1_555 ? 
5  AC2 3 C   B 9   ? C   D 509  . ? 1_555 ? 
6  AC2 3 A   B 45  ? A   D 545  . ? 1_555 ? 
7  AC2 3 A   B 46  ? A   D 546  . ? 1_555 ? 
8  AC3 9 ARG C 5   ? ARG A 5    . ? 1_555 ? 
9  AC3 9 ALA C 7   ? ALA A 7    . ? 1_555 ? 
10 AC3 9 GLU C 41  ? GLU A 41   . ? 1_555 ? 
11 AC3 9 TYR C 187 ? TYR A 187  . ? 1_555 ? 
12 AC3 9 ASN C 191 ? ASN A 191  . ? 1_555 ? 
13 AC3 9 ARG C 205 ? ARG A 205  . ? 1_555 ? 
14 AC3 9 TRP C 209 ? TRP A 209  . ? 1_555 ? 
15 AC3 9 HOH K .   ? HOH A 1167 . ? 1_555 ? 
16 AC3 9 A   A 75  ? A   C 576  . ? 1_555 ? 
17 AC4 9 HOH K .   ? HOH A 1104 . ? 1_555 ? 
18 AC4 9 ARG D 5   ? ARG B 5    . ? 1_555 ? 
19 AC4 9 ALA D 7   ? ALA B 7    . ? 1_555 ? 
20 AC4 9 GLU D 41  ? GLU B 41   . ? 1_555 ? 
21 AC4 9 TYR D 187 ? TYR B 187  . ? 1_555 ? 
22 AC4 9 ASN D 191 ? ASN B 191  . ? 1_555 ? 
23 AC4 9 ARG D 205 ? ARG B 205  . ? 1_555 ? 
24 AC4 9 TRP D 209 ? TRP B 209  . ? 1_555 ? 
25 AC4 9 A   B 75  ? A   D 576  . ? 1_555 ? 
# 
_database_PDB_matrix.entry_id          2CV0 
_database_PDB_matrix.origx[1][1]       1.000000 
_database_PDB_matrix.origx[1][2]       0.000000 
_database_PDB_matrix.origx[1][3]       0.000000 
_database_PDB_matrix.origx[2][1]       0.000000 
_database_PDB_matrix.origx[2][2]       1.000000 
_database_PDB_matrix.origx[2][3]       0.000000 
_database_PDB_matrix.origx[3][1]       0.000000 
_database_PDB_matrix.origx[3][2]       0.000000 
_database_PDB_matrix.origx[3][3]       1.000000 
_database_PDB_matrix.origx_vector[1]   0.00000 
_database_PDB_matrix.origx_vector[2]   0.00000 
_database_PDB_matrix.origx_vector[3]   0.00000 
# 
_atom_sites.entry_id                    2CV0 
_atom_sites.fract_transf_matrix[1][1]   0.009031 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.004560 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.007386 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     O  OP3   . G   A 1 1   ? 19.182  87.564  72.789  1.00 79.09  ? 501  G   C OP3   1 
ATOM   2     P  P     . G   A 1 1   ? 18.618  87.917  71.422  1.00 98.50  ? 501  G   C P     1 
ATOM   3     O  OP1   . G   A 1 1   ? 17.092  87.920  71.376  1.00 99.35  ? 501  G   C OP1   1 
ATOM   4     O  OP2   . G   A 1 1   ? 19.223  87.115  70.263  1.00 96.74  ? 501  G   C OP2   1 
ATOM   5     O  "O5'" . G   A 1 1   ? 19.088  89.454  71.168  1.00 81.08  ? 501  G   C "O5'" 1 
ATOM   6     C  "C5'" . G   A 1 1   ? 18.714  90.511  72.065  1.00 57.04  ? 501  G   C "C5'" 1 
ATOM   7     C  "C4'" . G   A 1 1   ? 19.513  91.752  71.737  1.00 54.79  ? 501  G   C "C4'" 1 
ATOM   8     O  "O4'" . G   A 1 1   ? 20.881  91.569  72.183  1.00 60.06  ? 501  G   C "O4'" 1 
ATOM   9     C  "C3'" . G   A 1 1   ? 19.621  92.023  70.247  1.00 52.20  ? 501  G   C "C3'" 1 
ATOM   10    O  "O3'" . G   A 1 1   ? 18.575  92.872  69.830  1.00 48.03  ? 501  G   C "O3'" 1 
ATOM   11    C  "C2'" . G   A 1 1   ? 20.959  92.726  70.121  1.00 49.07  ? 501  G   C "C2'" 1 
ATOM   12    O  "O2'" . G   A 1 1   ? 20.864  94.083  70.424  1.00 46.94  ? 501  G   C "O2'" 1 
ATOM   13    C  "C1'" . G   A 1 1   ? 21.787  92.013  71.188  1.00 47.02  ? 501  G   C "C1'" 1 
ATOM   14    N  N9    . G   A 1 1   ? 22.507  90.849  70.662  1.00 52.75  ? 501  G   C N9    1 
ATOM   15    C  C8    . G   A 1 1   ? 22.249  89.515  70.917  1.00 54.24  ? 501  G   C C8    1 
ATOM   16    N  N7    . G   A 1 1   ? 23.050  88.701  70.272  1.00 43.11  ? 501  G   C N7    1 
ATOM   17    C  C5    . G   A 1 1   ? 23.894  89.543  69.560  1.00 47.61  ? 501  G   C C5    1 
ATOM   18    C  C6    . G   A 1 1   ? 24.984  89.242  68.682  1.00 51.11  ? 501  G   C C6    1 
ATOM   19    O  O6    . G   A 1 1   ? 25.423  88.137  68.347  1.00 48.52  ? 501  G   C O6    1 
ATOM   20    N  N1    . G   A 1 1   ? 25.573  90.401  68.173  1.00 42.24  ? 501  G   C N1    1 
ATOM   21    C  C2    . G   A 1 1   ? 25.159  91.682  68.445  1.00 44.57  ? 501  G   C C2    1 
ATOM   22    N  N2    . G   A 1 1   ? 25.835  92.665  67.813  1.00 35.66  ? 501  G   C N2    1 
ATOM   23    N  N3    . G   A 1 1   ? 24.152  91.980  69.264  1.00 43.76  ? 501  G   C N3    1 
ATOM   24    C  C4    . G   A 1 1   ? 23.573  90.872  69.786  1.00 47.29  ? 501  G   C C4    1 
ATOM   25    P  P     . G   A 1 2   ? 17.952  92.687  68.383  1.00 55.53  ? 502  G   C P     1 
ATOM   26    O  OP1   . G   A 1 2   ? 16.664  93.439  68.360  1.00 66.53  ? 502  G   C OP1   1 
ATOM   27    O  OP2   . G   A 1 2   ? 17.962  91.226  68.075  1.00 57.91  ? 502  G   C OP2   1 
ATOM   28    O  "O5'" . G   A 1 2   ? 18.972  93.444  67.426  1.00 43.92  ? 502  G   C "O5'" 1 
ATOM   29    C  "C5'" . G   A 1 2   ? 18.975  94.861  67.373  1.00 45.63  ? 502  G   C "C5'" 1 
ATOM   30    C  "C4'" . G   A 1 2   ? 19.992  95.343  66.377  1.00 34.99  ? 502  G   C "C4'" 1 
ATOM   31    O  "O4'" . G   A 1 2   ? 21.311  94.921  66.809  1.00 45.74  ? 502  G   C "O4'" 1 
ATOM   32    C  "C3'" . G   A 1 2   ? 19.851  94.742  64.997  1.00 43.48  ? 502  G   C "C3'" 1 
ATOM   33    O  "O3'" . G   A 1 2   ? 18.909  95.459  64.229  1.00 44.05  ? 502  G   C "O3'" 1 
ATOM   34    C  "C2'" . G   A 1 2   ? 21.258  94.890  64.449  1.00 45.05  ? 502  G   C "C2'" 1 
ATOM   35    O  "O2'" . G   A 1 2   ? 21.536  96.206  64.037  1.00 43.23  ? 502  G   C "O2'" 1 
ATOM   36    C  "C1'" . G   A 1 2   ? 22.087  94.545  65.686  1.00 40.45  ? 502  G   C "C1'" 1 
ATOM   37    N  N9    . G   A 1 2   ? 22.403  93.114  65.789  1.00 45.08  ? 502  G   C N9    1 
ATOM   38    C  C8    . G   A 1 2   ? 21.777  92.162  66.560  1.00 38.00  ? 502  G   C C8    1 
ATOM   39    N  N7    . G   A 1 2   ? 22.304  90.973  66.440  1.00 37.98  ? 502  G   C N7    1 
ATOM   40    C  C5    . G   A 1 2   ? 23.340  91.148  65.535  1.00 36.09  ? 502  G   C C5    1 
ATOM   41    C  C6    . G   A 1 2   ? 24.288  90.210  65.010  1.00 39.79  ? 502  G   C C6    1 
ATOM   42    O  O6    . G   A 1 2   ? 24.409  88.994  65.256  1.00 37.13  ? 502  G   C O6    1 
ATOM   43    N  N1    . G   A 1 2   ? 25.154  90.821  64.112  1.00 31.76  ? 502  G   C N1    1 
ATOM   44    C  C2    . G   A 1 2   ? 25.123  92.147  63.759  1.00 35.35  ? 502  G   C C2    1 
ATOM   45    N  N2    . G   A 1 2   ? 26.023  92.535  62.870  1.00 37.57  ? 502  G   C N2    1 
ATOM   46    N  N3    . G   A 1 2   ? 24.266  93.026  64.239  1.00 36.94  ? 502  G   C N3    1 
ATOM   47    C  C4    . G   A 1 2   ? 23.407  92.461  65.116  1.00 40.67  ? 502  G   C C4    1 
ATOM   48    P  P     . C   A 1 3   ? 17.974  94.672  63.196  1.00 48.58  ? 503  C   C P     1 
ATOM   49    O  OP1   . C   A 1 3   ? 17.053  95.679  62.613  1.00 58.57  ? 503  C   C OP1   1 
ATOM   50    O  OP2   . C   A 1 3   ? 17.402  93.465  63.881  1.00 44.08  ? 503  C   C OP2   1 
ATOM   51    O  "O5'" . C   A 1 3   ? 18.997  94.234  62.052  1.00 41.95  ? 503  C   C "O5'" 1 
ATOM   52    C  "C5'" . C   A 1 3   ? 19.668  95.227  61.287  1.00 41.69  ? 503  C   C "C5'" 1 
ATOM   53    C  "C4'" . C   A 1 3   ? 20.726  94.599  60.426  1.00 46.84  ? 503  C   C "C4'" 1 
ATOM   54    O  "O4'" . C   A 1 3   ? 21.788  94.072  61.271  1.00 49.44  ? 503  C   C "O4'" 1 
ATOM   55    C  "C3'" . C   A 1 3   ? 20.266  93.400  59.617  1.00 45.66  ? 503  C   C "C3'" 1 
ATOM   56    O  "O3'" . C   A 1 3   ? 19.640  93.802  58.409  1.00 41.11  ? 503  C   C "O3'" 1 
ATOM   57    C  "C2'" . C   A 1 3   ? 21.586  92.701  59.352  1.00 41.91  ? 503  C   C "C2'" 1 
ATOM   58    O  "O2'" . C   A 1 3   ? 22.308  93.367  58.346  1.00 44.62  ? 503  C   C "O2'" 1 
ATOM   59    C  "C1'" . C   A 1 3   ? 22.290  92.876  60.702  1.00 48.75  ? 503  C   C "C1'" 1 
ATOM   60    N  N1    . C   A 1 3   ? 21.981  91.763  61.615  1.00 46.72  ? 503  C   C N1    1 
ATOM   61    C  C2    . C   A 1 3   ? 22.730  90.584  61.505  1.00 45.82  ? 503  C   C C2    1 
ATOM   62    O  O2    . C   A 1 3   ? 23.648  90.535  60.662  1.00 43.14  ? 503  C   C O2    1 
ATOM   63    N  N3    . C   A 1 3   ? 22.443  89.537  62.320  1.00 39.91  ? 503  C   C N3    1 
ATOM   64    C  C4    . C   A 1 3   ? 21.466  89.650  63.227  1.00 42.05  ? 503  C   C C4    1 
ATOM   65    N  N4    . C   A 1 3   ? 21.239  88.615  64.034  1.00 35.79  ? 503  C   C N4    1 
ATOM   66    C  C5    . C   A 1 3   ? 20.686  90.839  63.353  1.00 36.88  ? 503  C   C C5    1 
ATOM   67    C  C6    . C   A 1 3   ? 20.978  91.862  62.539  1.00 35.34  ? 503  C   C C6    1 
ATOM   68    P  P     . C   A 1 4   ? 18.524  92.861  57.745  1.00 47.00  ? 504  C   C P     1 
ATOM   69    O  OP1   . C   A 1 4   ? 17.983  93.618  56.598  1.00 48.66  ? 504  C   C OP1   1 
ATOM   70    O  OP2   . C   A 1 4   ? 17.610  92.376  58.810  1.00 37.50  ? 504  C   C OP2   1 
ATOM   71    O  "O5'" . C   A 1 4   ? 19.336  91.604  57.183  1.00 52.71  ? 504  C   C "O5'" 1 
ATOM   72    C  "C5'" . C   A 1 4   ? 20.274  91.756  56.122  1.00 43.15  ? 504  C   C "C5'" 1 
ATOM   73    C  "C4'" . C   A 1 4   ? 21.049  90.474  55.913  1.00 54.33  ? 504  C   C "C4'" 1 
ATOM   74    O  "O4'" . C   A 1 4   ? 21.828  90.164  57.100  1.00 49.97  ? 504  C   C "O4'" 1 
ATOM   75    C  "C3'" . C   A 1 4   ? 20.250  89.201  55.675  1.00 44.53  ? 504  C   C "C3'" 1 
ATOM   76    O  "O3'" . C   A 1 4   ? 19.814  89.117  54.327  1.00 44.59  ? 504  C   C "O3'" 1 
ATOM   77    C  "C2'" . C   A 1 4   ? 21.302  88.148  55.986  1.00 48.15  ? 504  C   C "C2'" 1 
ATOM   78    O  "O2'" . C   A 1 4   ? 22.312  88.073  54.992  1.00 45.77  ? 504  C   C "O2'" 1 
ATOM   79    C  "C1'" . C   A 1 4   ? 21.938  88.756  57.236  1.00 54.61  ? 504  C   C "C1'" 1 
ATOM   80    N  N1    . C   A 1 4   ? 21.226  88.350  58.454  1.00 45.82  ? 504  C   C N1    1 
ATOM   81    C  C2    . C   A 1 4   ? 21.437  87.067  58.962  1.00 48.36  ? 504  C   C C2    1 
ATOM   82    O  O2    . C   A 1 4   ? 22.215  86.300  58.366  1.00 58.14  ? 504  C   C O2    1 
ATOM   83    N  N3    . C   A 1 4   ? 20.794  86.691  60.085  1.00 46.95  ? 504  C   C N3    1 
ATOM   84    C  C4    . C   A 1 4   ? 19.975  87.539  60.701  1.00 42.22  ? 504  C   C C4    1 
ATOM   85    N  N4    . C   A 1 4   ? 19.391  87.134  61.828  1.00 50.41  ? 504  C   C N4    1 
ATOM   86    C  C5    . C   A 1 4   ? 19.727  88.846  60.197  1.00 51.27  ? 504  C   C C5    1 
ATOM   87    C  C6    . C   A 1 4   ? 20.370  89.208  59.081  1.00 53.03  ? 504  C   C C6    1 
ATOM   88    P  P     . C   A 1 5   ? 18.516  88.247  53.967  1.00 42.32  ? 505  C   C P     1 
ATOM   89    O  OP1   . C   A 1 5   ? 18.081  88.613  52.593  1.00 52.54  ? 505  C   C OP1   1 
ATOM   90    O  OP2   . C   A 1 5   ? 17.562  88.406  55.097  1.00 54.32  ? 505  C   C OP2   1 
ATOM   91    O  "O5'" . C   A 1 5   ? 19.027  86.726  54.005  1.00 46.56  ? 505  C   C "O5'" 1 
ATOM   92    C  "C5'" . C   A 1 5   ? 20.116  86.263  53.183  1.00 38.90  ? 505  C   C "C5'" 1 
ATOM   93    C  "C4'" . C   A 1 5   ? 20.512  84.842  53.568  1.00 34.82  ? 505  C   C "C4'" 1 
ATOM   94    O  "O4'" . C   A 1 5   ? 21.073  84.819  54.914  1.00 42.47  ? 505  C   C "O4'" 1 
ATOM   95    C  "C3'" . C   A 1 5   ? 19.376  83.839  53.656  1.00 44.75  ? 505  C   C "C3'" 1 
ATOM   96    O  "O3'" . C   A 1 5   ? 19.000  83.314  52.403  1.00 35.16  ? 505  C   C "O3'" 1 
ATOM   97    C  "C2'" . C   A 1 5   ? 19.961  82.760  54.555  1.00 37.34  ? 505  C   C "C2'" 1 
ATOM   98    O  "O2'" . C   A 1 5   ? 20.899  81.963  53.880  1.00 39.14  ? 505  C   C "O2'" 1 
ATOM   99    C  "C1'" . C   A 1 5   ? 20.699  83.610  55.580  1.00 45.11  ? 505  C   C "C1'" 1 
ATOM   100   N  N1    . C   A 1 5   ? 19.839  83.936  56.741  1.00 51.11  ? 505  C   C N1    1 
ATOM   101   C  C2    . C   A 1 5   ? 19.772  83.031  57.825  1.00 46.71  ? 505  C   C C2    1 
ATOM   102   O  O2    . C   A 1 5   ? 20.429  81.988  57.782  1.00 57.28  ? 505  C   C O2    1 
ATOM   103   N  N3    . C   A 1 5   ? 18.995  83.327  58.885  1.00 50.81  ? 505  C   C N3    1 
ATOM   104   C  C4    . C   A 1 5   ? 18.303  84.474  58.905  1.00 52.73  ? 505  C   C C4    1 
ATOM   105   N  N4    . C   A 1 5   ? 17.561  84.742  59.986  1.00 40.26  ? 505  C   C N4    1 
ATOM   106   C  C5    . C   A 1 5   ? 18.343  85.401  57.818  1.00 46.64  ? 505  C   C C5    1 
ATOM   107   C  C6    . C   A 1 5   ? 19.114  85.095  56.769  1.00 48.11  ? 505  C   C C6    1 
ATOM   108   P  P     . C   A 1 6   ? 17.521  82.727  52.227  1.00 47.29  ? 506  C   C P     1 
ATOM   109   O  OP1   . C   A 1 6   ? 17.325  82.342  50.801  1.00 43.75  ? 506  C   C OP1   1 
ATOM   110   O  OP2   . C   A 1 6   ? 16.577  83.683  52.876  1.00 43.10  ? 506  C   C OP2   1 
ATOM   111   O  "O5'" . C   A 1 6   ? 17.489  81.418  53.137  1.00 38.35  ? 506  C   C "O5'" 1 
ATOM   112   C  "C5'" . C   A 1 6   ? 18.269  80.271  52.823  1.00 45.11  ? 506  C   C "C5'" 1 
ATOM   113   C  "C4'" . C   A 1 6   ? 18.149  79.240  53.924  1.00 45.52  ? 506  C   C "C4'" 1 
ATOM   114   O  "O4'" . C   A 1 6   ? 18.519  79.853  55.190  1.00 56.62  ? 506  C   C "O4'" 1 
ATOM   115   C  "C3'" . C   A 1 6   ? 16.755  78.693  54.177  1.00 50.71  ? 506  C   C "C3'" 1 
ATOM   116   O  "O3'" . C   A 1 6   ? 16.514  77.597  53.307  1.00 44.20  ? 506  C   C "O3'" 1 
ATOM   117   C  "C2'" . C   A 1 6   ? 16.848  78.220  55.624  1.00 52.12  ? 506  C   C "C2'" 1 
ATOM   118   O  "O2'" . C   A 1 6   ? 17.487  76.970  55.743  1.00 54.84  ? 506  C   C "O2'" 1 
ATOM   119   C  "C1'" . C   A 1 6   ? 17.769  79.272  56.240  1.00 47.80  ? 506  C   C "C1'" 1 
ATOM   120   N  N1    . C   A 1 6   ? 17.045  80.332  56.947  1.00 45.51  ? 506  C   C N1    1 
ATOM   121   C  C2    . C   A 1 6   ? 16.476  80.031  58.191  1.00 52.02  ? 506  C   C C2    1 
ATOM   122   O  O2    . C   A 1 6   ? 16.594  78.886  58.633  1.00 56.21  ? 506  C   C O2    1 
ATOM   123   N  N3    . C   A 1 6   ? 15.814  80.995  58.873  1.00 51.03  ? 506  C   C N3    1 
ATOM   124   C  C4    . C   A 1 6   ? 15.716  82.223  58.357  1.00 49.45  ? 506  C   C C4    1 
ATOM   125   N  N4    . C   A 1 6   ? 15.078  83.158  59.078  1.00 51.40  ? 506  C   C N4    1 
ATOM   126   C  C5    . C   A 1 6   ? 16.273  82.551  57.080  1.00 46.78  ? 506  C   C C5    1 
ATOM   127   C  C6    . C   A 1 6   ? 16.923  81.583  56.417  1.00 40.51  ? 506  C   C C6    1 
ATOM   128   P  P     . A   A 1 7   ? 15.009  77.146  52.995  1.00 52.44  ? 507  A   C P     1 
ATOM   129   O  OP1   . A   A 1 7   ? 15.078  76.096  51.963  1.00 56.56  ? 507  A   C OP1   1 
ATOM   130   O  OP2   . A   A 1 7   ? 14.211  78.384  52.744  1.00 55.08  ? 507  A   C OP2   1 
ATOM   131   O  "O5'" . A   A 1 7   ? 14.502  76.461  54.344  1.00 55.87  ? 507  A   C "O5'" 1 
ATOM   132   C  "C5'" . A   A 1 7   ? 15.249  75.409  54.946  1.00 51.46  ? 507  A   C "C5'" 1 
ATOM   133   C  "C4'" . A   A 1 7   ? 14.435  74.714  56.019  1.00 60.03  ? 507  A   C "C4'" 1 
ATOM   134   O  "O4'" . A   A 1 7   ? 14.263  75.605  57.158  1.00 58.87  ? 507  A   C "O4'" 1 
ATOM   135   C  "C3'" . A   A 1 7   ? 13.036  74.399  55.518  1.00 69.20  ? 507  A   C "C3'" 1 
ATOM   136   O  "O3'" . A   A 1 7   ? 12.591  73.035  55.385  1.00 71.27  ? 507  A   C "O3'" 1 
ATOM   137   C  "C2'" . A   A 1 7   ? 12.116  75.490  56.073  1.00 68.82  ? 507  A   C "C2'" 1 
ATOM   138   O  "O2'" . A   A 1 7   ? 10.912  74.982  56.601  1.00 82.11  ? 507  A   C "O2'" 1 
ATOM   139   C  "C1'" . A   A 1 7   ? 12.914  76.014  57.267  1.00 70.43  ? 507  A   C "C1'" 1 
ATOM   140   N  N9    . A   A 1 7   ? 12.859  77.462  57.465  1.00 75.77  ? 507  A   C N9    1 
ATOM   141   C  C8    . A   A 1 7   ? 13.295  78.456  56.627  1.00 76.32  ? 507  A   C C8    1 
ATOM   142   N  N7    . A   A 1 7   ? 13.102  79.665  57.097  1.00 72.11  ? 507  A   C N7    1 
ATOM   143   C  C5    . A   A 1 7   ? 12.495  79.454  58.326  1.00 73.23  ? 507  A   C C5    1 
ATOM   144   C  C6    . A   A 1 7   ? 12.042  80.337  59.321  1.00 74.41  ? 507  A   C C6    1 
ATOM   145   N  N6    . A   A 1 7   ? 12.150  81.661  59.235  1.00 78.35  ? 507  A   C N6    1 
ATOM   146   N  N1    . A   A 1 7   ? 11.474  79.806  60.427  1.00 71.61  ? 507  A   C N1    1 
ATOM   147   C  C2    . A   A 1 7   ? 11.390  78.475  60.523  1.00 68.24  ? 507  A   C C2    1 
ATOM   148   N  N3    . A   A 1 7   ? 11.789  77.540  59.661  1.00 72.95  ? 507  A   C N3    1 
ATOM   149   C  C4    . A   A 1 7   ? 12.337  78.103  58.567  1.00 76.88  ? 507  A   C C4    1 
ATOM   150   P  P     . U   A 1 8   ? 13.280  71.840  56.246  1.00 78.15  ? 508  U   C P     1 
ATOM   151   O  OP1   . U   A 1 8   ? 13.294  72.255  57.677  1.00 82.07  ? 508  U   C OP1   1 
ATOM   152   O  OP2   . U   A 1 8   ? 14.534  71.308  55.635  1.00 73.39  ? 508  U   C OP2   1 
ATOM   153   O  "O5'" . U   A 1 8   ? 12.185  70.701  56.109  1.00 64.48  ? 508  U   C "O5'" 1 
ATOM   154   C  "C5'" . U   A 1 8   ? 10.830  70.972  56.437  1.00 41.90  ? 508  U   C "C5'" 1 
ATOM   155   C  "C4'" . U   A 1 8   ? 9.978   69.766  56.146  1.00 45.60  ? 508  U   C "C4'" 1 
ATOM   156   O  "O4'" . U   A 1 8   ? 9.712   69.668  54.722  1.00 50.63  ? 508  U   C "O4'" 1 
ATOM   157   C  "C3'" . U   A 1 8   ? 10.626  68.444  56.497  1.00 37.08  ? 508  U   C "C3'" 1 
ATOM   158   O  "O3'" . U   A 1 8   ? 10.445  68.181  57.877  1.00 46.22  ? 508  U   C "O3'" 1 
ATOM   159   C  "C2'" . U   A 1 8   ? 9.848   67.492  55.612  1.00 45.33  ? 508  U   C "C2'" 1 
ATOM   160   O  "O2'" . U   A 1 8   ? 8.549   67.325  56.129  1.00 48.07  ? 508  U   C "O2'" 1 
ATOM   161   C  "C1'" . U   A 1 8   ? 9.731   68.312  54.325  1.00 47.93  ? 508  U   C "C1'" 1 
ATOM   162   N  N1    . U   A 1 8   ? 10.849  68.133  53.385  1.00 46.26  ? 508  U   C N1    1 
ATOM   163   C  C2    . U   A 1 8   ? 10.722  67.177  52.399  1.00 40.96  ? 508  U   C C2    1 
ATOM   164   O  O2    . U   A 1 8   ? 9.718   66.507  52.248  1.00 38.26  ? 508  U   C O2    1 
ATOM   165   N  N3    . U   A 1 8   ? 11.809  67.050  51.576  1.00 41.03  ? 508  U   C N3    1 
ATOM   166   C  C4    . U   A 1 8   ? 12.976  67.782  51.618  1.00 48.83  ? 508  U   C C4    1 
ATOM   167   O  O4    . U   A 1 8   ? 13.844  67.589  50.763  1.00 46.00  ? 508  U   C O4    1 
ATOM   168   C  C5    . U   A 1 8   ? 13.025  68.766  52.660  1.00 38.09  ? 508  U   C C5    1 
ATOM   169   C  C6    . U   A 1 8   ? 11.989  68.900  53.486  1.00 43.60  ? 508  U   C C6    1 
ATOM   170   P  P     . C   A 1 9   ? 11.646  67.550  58.735  1.00 52.62  ? 509  C   C P     1 
ATOM   171   O  OP1   . C   A 1 9   ? 11.275  67.707  60.159  1.00 56.21  ? 509  C   C OP1   1 
ATOM   172   O  OP2   . C   A 1 9   ? 12.948  68.103  58.248  1.00 55.66  ? 509  C   C OP2   1 
ATOM   173   O  "O5'" . C   A 1 9   ? 11.576  66.005  58.335  1.00 54.58  ? 509  C   C "O5'" 1 
ATOM   174   C  "C5'" . C   A 1 9   ? 12.247  65.002  59.089  1.00 43.73  ? 509  C   C "C5'" 1 
ATOM   175   C  "C4'" . C   A 1 9   ? 11.244  64.004  59.587  1.00 36.84  ? 509  C   C "C4'" 1 
ATOM   176   O  "O4'" . C   A 1 9   ? 10.636  63.375  58.435  1.00 43.42  ? 509  C   C "O4'" 1 
ATOM   177   C  "C3'" . C   A 1 9   ? 11.930  62.877  60.356  1.00 33.62  ? 509  C   C "C3'" 1 
ATOM   178   O  "O3'" . C   A 1 9   ? 11.336  62.571  61.607  1.00 38.13  ? 509  C   C "O3'" 1 
ATOM   179   C  "C2'" . C   A 1 9   ? 12.047  61.700  59.401  1.00 37.99  ? 509  C   C "C2'" 1 
ATOM   180   O  "O2'" . C   A 1 9   ? 11.705  60.482  60.037  1.00 35.19  ? 509  C   C "O2'" 1 
ATOM   181   C  "C1'" . C   A 1 9   ? 10.919  61.998  58.435  1.00 33.96  ? 509  C   C "C1'" 1 
ATOM   182   N  N1    . C   A 1 9   ? 10.944  61.470  57.075  1.00 46.48  ? 509  C   C N1    1 
ATOM   183   C  C2    . C   A 1 9   ? 9.846   60.693  56.659  1.00 50.25  ? 509  C   C C2    1 
ATOM   184   O  O2    . C   A 1 9   ? 8.909   60.486  57.463  1.00 48.01  ? 509  C   C O2    1 
ATOM   185   N  N3    . C   A 1 9   ? 9.831   60.193  55.407  1.00 50.24  ? 509  C   C N3    1 
ATOM   186   C  C4    . C   A 1 9   ? 10.861  60.423  54.585  1.00 43.37  ? 509  C   C C4    1 
ATOM   187   N  N4    . C   A 1 9   ? 10.817  59.885  53.366  1.00 31.62  ? 509  C   C N4    1 
ATOM   188   C  C5    . C   A 1 9   ? 11.984  61.209  54.982  1.00 41.80  ? 509  C   C C5    1 
ATOM   189   C  C6    . C   A 1 9   ? 11.984  61.709  56.225  1.00 45.92  ? 509  C   C C6    1 
ATOM   190   P  P     . G   A 1 10  ? 11.590  63.522  62.863  1.00 43.29  ? 510  G   C P     1 
ATOM   191   O  OP1   . G   A 1 10  ? 10.747  63.020  63.981  1.00 52.15  ? 510  G   C OP1   1 
ATOM   192   O  OP2   . G   A 1 10  ? 11.439  64.923  62.401  1.00 44.94  ? 510  G   C OP2   1 
ATOM   193   O  "O5'" . G   A 1 10  ? 13.111  63.286  63.240  1.00 38.38  ? 510  G   C "O5'" 1 
ATOM   194   C  "C5'" . G   A 1 10  ? 13.681  63.965  64.344  1.00 37.65  ? 510  G   C "C5'" 1 
ATOM   195   C  "C4'" . G   A 1 10  ? 15.121  63.585  64.470  1.00 42.43  ? 510  G   C "C4'" 1 
ATOM   196   O  "O4'" . G   A 1 10  ? 15.184  62.142  64.601  1.00 45.66  ? 510  G   C "O4'" 1 
ATOM   197   C  "C3'" . G   A 1 10  ? 15.935  63.878  63.220  1.00 40.95  ? 510  G   C "C3'" 1 
ATOM   198   O  "O3'" . G   A 1 10  ? 16.456  65.189  63.295  1.00 34.34  ? 510  G   C "O3'" 1 
ATOM   199   C  "C2'" . G   A 1 10  ? 17.034  62.845  63.320  1.00 39.49  ? 510  G   C "C2'" 1 
ATOM   200   O  "O2'" . G   A 1 10  ? 17.980  63.238  64.293  1.00 46.55  ? 510  G   C "O2'" 1 
ATOM   201   C  "C1'" . G   A 1 10  ? 16.247  61.633  63.823  1.00 35.15  ? 510  G   C "C1'" 1 
ATOM   202   N  N9    . G   A 1 10  ? 15.652  60.845  62.751  1.00 39.31  ? 510  G   C N9    1 
ATOM   203   C  C8    . G   A 1 10  ? 14.312  60.679  62.496  1.00 38.40  ? 510  G   C C8    1 
ATOM   204   N  N7    . G   A 1 10  ? 14.074  59.913  61.460  1.00 35.88  ? 510  G   C N7    1 
ATOM   205   C  C5    . G   A 1 10  ? 15.337  59.544  61.012  1.00 39.16  ? 510  G   C C5    1 
ATOM   206   C  C6    . G   A 1 10  ? 15.719  58.716  59.933  1.00 35.78  ? 510  G   C C6    1 
ATOM   207   O  O6    . G   A 1 10  ? 15.001  58.098  59.148  1.00 33.98  ? 510  G   C O6    1 
ATOM   208   N  N1    . G   A 1 10  ? 17.098  58.640  59.810  1.00 42.94  ? 510  G   C N1    1 
ATOM   209   C  C2    . G   A 1 10  ? 17.998  59.272  60.625  1.00 44.08  ? 510  G   C C2    1 
ATOM   210   N  N2    . G   A 1 10  ? 19.292  59.100  60.319  1.00 38.91  ? 510  G   C N2    1 
ATOM   211   N  N3    . G   A 1 10  ? 17.659  60.024  61.657  1.00 40.24  ? 510  G   C N3    1 
ATOM   212   C  C4    . G   A 1 10  ? 16.322  60.120  61.788  1.00 42.06  ? 510  G   C C4    1 
ATOM   213   P  P     . U   A 1 11  ? 16.635  66.048  61.955  1.00 36.46  ? 511  U   C P     1 
ATOM   214   O  OP1   . U   A 1 11  ? 17.108  67.386  62.376  1.00 41.70  ? 511  U   C OP1   1 
ATOM   215   O  OP2   . U   A 1 11  ? 15.432  65.944  61.121  1.00 32.13  ? 511  U   C OP2   1 
ATOM   216   O  "O5'" . U   A 1 11  ? 17.799  65.266  61.195  1.00 37.65  ? 511  U   C "O5'" 1 
ATOM   217   C  "C5'" . U   A 1 11  ? 19.132  65.264  61.690  1.00 25.02  ? 511  U   C "C5'" 1 
ATOM   218   C  "C4'" . U   A 1 11  ? 20.041  64.560  60.711  1.00 37.05  ? 511  U   C "C4'" 1 
ATOM   219   O  "O4'" . U   A 1 11  ? 19.696  63.144  60.674  1.00 33.06  ? 511  U   C "O4'" 1 
ATOM   220   C  "C3'" . U   A 1 11  ? 19.901  65.011  59.258  1.00 36.24  ? 511  U   C "C3'" 1 
ATOM   221   O  "O3'" . U   A 1 11  ? 20.680  66.178  58.986  1.00 37.99  ? 511  U   C "O3'" 1 
ATOM   222   C  "C2'" . U   A 1 11  ? 20.414  63.792  58.511  1.00 39.88  ? 511  U   C "C2'" 1 
ATOM   223   O  "O2'" . U   A 1 11  ? 21.827  63.704  58.571  1.00 43.81  ? 511  U   C "O2'" 1 
ATOM   224   C  "C1'" . U   A 1 11  ? 19.812  62.657  59.349  1.00 40.87  ? 511  U   C "C1'" 1 
ATOM   225   N  N1    . U   A 1 11  ? 18.483  62.227  58.882  1.00 40.16  ? 511  U   C N1    1 
ATOM   226   C  C2    . U   A 1 11  ? 18.438  61.435  57.749  1.00 44.20  ? 511  U   C C2    1 
ATOM   227   O  O2    . U   A 1 11  ? 19.438  61.073  57.167  1.00 46.52  ? 511  U   C O2    1 
ATOM   228   N  N3    . U   A 1 11  ? 17.178  61.077  57.331  1.00 40.43  ? 511  U   C N3    1 
ATOM   229   C  C4    . U   A 1 11  ? 15.984  61.423  57.920  1.00 41.14  ? 511  U   C C4    1 
ATOM   230   O  O4    . U   A 1 11  ? 14.931  61.016  57.430  1.00 42.89  ? 511  U   C O4    1 
ATOM   231   C  C5    . U   A 1 11  ? 16.109  62.238  59.097  1.00 36.89  ? 511  U   C C5    1 
ATOM   232   C  C6    . U   A 1 11  ? 17.322  62.599  59.530  1.00 40.70  ? 511  U   C C6    1 
ATOM   233   P  P     . C   A 1 12  ? 20.284  67.135  57.745  1.00 37.39  ? 512  C   C P     1 
ATOM   234   O  OP1   . C   A 1 12  ? 21.126  68.363  57.809  1.00 36.27  ? 512  C   C OP1   1 
ATOM   235   O  OP2   . C   A 1 12  ? 18.826  67.270  57.694  1.00 32.51  ? 512  C   C OP2   1 
ATOM   236   O  "O5'" . C   A 1 12  ? 20.679  66.268  56.461  1.00 41.89  ? 512  C   C "O5'" 1 
ATOM   237   C  "C5'" . C   A 1 12  ? 22.041  65.953  56.168  1.00 29.99  ? 512  C   C "C5'" 1 
ATOM   238   C  "C4'" . C   A 1 12  ? 22.143  65.332  54.796  1.00 27.67  ? 512  C   C "C4'" 1 
ATOM   239   O  "O4'" . C   A 1 12  ? 21.585  63.999  54.857  1.00 31.38  ? 512  C   C "O4'" 1 
ATOM   240   C  "C3'" . C   A 1 12  ? 21.327  66.008  53.708  1.00 27.15  ? 512  C   C "C3'" 1 
ATOM   241   O  "O3'" . C   A 1 12  ? 21.942  67.165  53.160  1.00 38.56  ? 512  C   C "O3'" 1 
ATOM   242   C  "C2'" . C   A 1 12  ? 21.123  64.876  52.705  1.00 34.65  ? 512  C   C "C2'" 1 
ATOM   243   O  "O2'" . C   A 1 12  ? 22.224  64.576  51.874  1.00 35.67  ? 512  C   C "O2'" 1 
ATOM   244   C  "C1'" . C   A 1 12  ? 20.907  63.696  53.648  1.00 37.28  ? 512  C   C "C1'" 1 
ATOM   245   N  N1    . C   A 1 12  ? 19.484  63.512  53.943  1.00 35.09  ? 512  C   C N1    1 
ATOM   246   C  C2    . C   A 1 12  ? 18.720  62.785  53.042  1.00 36.19  ? 512  C   C C2    1 
ATOM   247   O  O2    . C   A 1 12  ? 19.287  62.306  52.053  1.00 37.57  ? 512  C   C O2    1 
ATOM   248   N  N3    . C   A 1 12  ? 17.390  62.619  53.269  1.00 33.28  ? 512  C   C N3    1 
ATOM   249   C  C4    . C   A 1 12  ? 16.838  63.137  54.365  1.00 36.11  ? 512  C   C C4    1 
ATOM   250   N  N4    . C   A 1 12  ? 15.539  62.929  54.568  1.00 35.35  ? 512  C   C N4    1 
ATOM   251   C  C5    . C   A 1 12  ? 17.602  63.888  55.310  1.00 44.83  ? 512  C   C C5    1 
ATOM   252   C  C6    . C   A 1 12  ? 18.910  64.048  55.063  1.00 35.53  ? 512  C   C C6    1 
ATOM   253   P  P     . U   A 1 13  ? 21.017  68.315  52.509  1.00 40.49  ? 513  U   C P     1 
ATOM   254   O  OP1   . U   A 1 13  ? 21.894  69.296  51.821  1.00 50.70  ? 513  U   C OP1   1 
ATOM   255   O  OP2   . U   A 1 13  ? 20.052  68.782  53.537  1.00 41.42  ? 513  U   C OP2   1 
ATOM   256   O  "O5'" . U   A 1 13  ? 20.229  67.502  51.405  1.00 38.22  ? 513  U   C "O5'" 1 
ATOM   257   C  "C5'" . U   A 1 13  ? 18.979  67.904  50.911  1.00 27.51  ? 513  U   C "C5'" 1 
ATOM   258   C  "C4'" . U   A 1 13  ? 18.419  66.774  50.092  1.00 42.32  ? 513  U   C "C4'" 1 
ATOM   259   O  "O4'" . U   A 1 13  ? 18.117  65.637  50.955  1.00 43.65  ? 513  U   C "O4'" 1 
ATOM   260   C  "C3'" . U   A 1 13  ? 17.126  67.052  49.369  1.00 44.60  ? 513  U   C "C3'" 1 
ATOM   261   O  "O3'" . U   A 1 13  ? 17.424  67.710  48.152  1.00 44.80  ? 513  U   C "O3'" 1 
ATOM   262   C  "C2'" . U   A 1 13  ? 16.586  65.646  49.149  1.00 37.53  ? 513  U   C "C2'" 1 
ATOM   263   O  "O2'" . U   A 1 13  ? 17.234  64.987  48.091  1.00 32.97  ? 513  U   C "O2'" 1 
ATOM   264   C  "C1'" . U   A 1 13  ? 16.966  64.967  50.467  1.00 39.14  ? 513  U   C "C1'" 1 
ATOM   265   N  N1    . U   A 1 13  ? 15.900  65.055  51.479  1.00 37.55  ? 513  U   C N1    1 
ATOM   266   C  C2    . U   A 1 13  ? 14.753  64.335  51.240  1.00 35.71  ? 513  U   C C2    1 
ATOM   267   O  O2    . U   A 1 13  ? 14.606  63.678  50.226  1.00 29.71  ? 513  U   C O2    1 
ATOM   268   N  N3    . U   A 1 13  ? 13.786  64.424  52.217  1.00 25.43  ? 513  U   C N3    1 
ATOM   269   C  C4    . U   A 1 13  ? 13.851  65.153  53.369  1.00 30.99  ? 513  U   C C4    1 
ATOM   270   O  O4    . U   A 1 13  ? 12.877  65.186  54.116  1.00 41.88  ? 513  U   C O4    1 
ATOM   271   C  C5    . U   A 1 13  ? 15.071  65.892  53.544  1.00 36.38  ? 513  U   C C5    1 
ATOM   272   C  C6    . U   A 1 13  ? 16.029  65.819  52.616  1.00 40.22  ? 513  U   C C6    1 
ATOM   273   P  P     . A   A 1 14  ? 16.342  68.693  47.509  1.00 45.00  ? 514  A   C P     1 
ATOM   274   O  OP1   . A   A 1 14  ? 17.017  69.472  46.443  1.00 55.89  ? 514  A   C OP1   1 
ATOM   275   O  OP2   . A   A 1 14  ? 15.676  69.403  48.633  1.00 39.34  ? 514  A   C OP2   1 
ATOM   276   O  "O5'" . A   A 1 14  ? 15.347  67.683  46.786  1.00 42.65  ? 514  A   C "O5'" 1 
ATOM   277   C  "C5'" . A   A 1 14  ? 15.861  66.768  45.829  1.00 42.57  ? 514  A   C "C5'" 1 
ATOM   278   C  "C4'" . A   A 1 14  ? 14.760  65.937  45.236  1.00 41.89  ? 514  A   C "C4'" 1 
ATOM   279   O  "O4'" . A   A 1 14  ? 14.250  64.987  46.206  1.00 41.86  ? 514  A   C "O4'" 1 
ATOM   280   C  "C3'" . A   A 1 14  ? 13.528  66.695  44.795  1.00 39.41  ? 514  A   C "C3'" 1 
ATOM   281   O  "O3'" . A   A 1 14  ? 13.770  67.287  43.530  1.00 36.30  ? 514  A   C "O3'" 1 
ATOM   282   C  "C2'" . A   A 1 14  ? 12.505  65.567  44.716  1.00 39.48  ? 514  A   C "C2'" 1 
ATOM   283   O  "O2'" . A   A 1 14  ? 12.679  64.767  43.574  1.00 32.70  ? 514  A   C "O2'" 1 
ATOM   284   C  "C1'" . A   A 1 14  ? 12.889  64.715  45.923  1.00 37.26  ? 514  A   C "C1'" 1 
ATOM   285   N  N9    . A   A 1 14  ? 12.094  64.999  47.118  1.00 43.29  ? 514  A   C N9    1 
ATOM   286   C  C8    . A   A 1 14  ? 12.484  65.649  48.258  1.00 44.23  ? 514  A   C C8    1 
ATOM   287   N  N7    . A   A 1 14  ? 11.553  65.710  49.178  1.00 50.51  ? 514  A   C N7    1 
ATOM   288   C  C5    . A   A 1 14  ? 10.470  65.067  48.597  1.00 50.20  ? 514  A   C C5    1 
ATOM   289   C  C6    . A   A 1 14  ? 9.176   64.776  49.069  1.00 43.17  ? 514  A   C C6    1 
ATOM   290   N  N6    . A   A 1 14  ? 8.748   65.092  50.290  1.00 38.47  ? 514  A   C N6    1 
ATOM   291   N  N1    . A   A 1 14  ? 8.339   64.125  48.239  1.00 38.93  ? 514  A   C N1    1 
ATOM   292   C  C2    . A   A 1 14  ? 8.780   63.778  47.027  1.00 38.93  ? 514  A   C C2    1 
ATOM   293   N  N3    . A   A 1 14  ? 9.975   63.980  46.474  1.00 47.58  ? 514  A   C N3    1 
ATOM   294   C  C4    . A   A 1 14  ? 10.785  64.636  47.324  1.00 47.27  ? 514  A   C C4    1 
ATOM   295   P  P     . G   A 1 15  ? 13.221  68.759  43.216  1.00 45.08  ? 515  G   C P     1 
ATOM   296   O  OP1   . G   A 1 15  ? 13.551  68.953  41.790  1.00 38.89  ? 515  G   C OP1   1 
ATOM   297   O  OP2   . G   A 1 15  ? 13.707  69.738  44.232  1.00 40.80  ? 515  G   C OP2   1 
ATOM   298   O  "O5'" . G   A 1 15  ? 11.636  68.622  43.376  1.00 51.26  ? 515  G   C "O5'" 1 
ATOM   299   C  "C5'" . G   A 1 15  ? 10.964  67.599  42.670  1.00 55.26  ? 515  G   C "C5'" 1 
ATOM   300   C  "C4'" . G   A 1 15  ? 9.550   67.389  43.168  1.00 59.71  ? 515  G   C "C4'" 1 
ATOM   301   O  "O4'" . G   A 1 15  ? 9.525   67.094  44.602  1.00 52.37  ? 515  G   C "O4'" 1 
ATOM   302   C  "C3'" . G   A 1 15  ? 8.723   68.659  42.994  1.00 61.28  ? 515  G   C "C3'" 1 
ATOM   303   O  "O3'" . G   A 1 15  ? 7.488   68.426  42.328  1.00 77.79  ? 515  G   C "O3'" 1 
ATOM   304   C  "C2'" . G   A 1 15  ? 8.645   69.314  44.363  1.00 52.69  ? 515  G   C "C2'" 1 
ATOM   305   O  "O2'" . G   A 1 15  ? 7.357   69.805  44.635  1.00 64.38  ? 515  G   C "O2'" 1 
ATOM   306   C  "C1'" . G   A 1 15  ? 8.831   68.109  45.282  1.00 46.00  ? 515  G   C "C1'" 1 
ATOM   307   N  N9    . G   A 1 15  ? 9.396   68.378  46.593  1.00 45.06  ? 515  G   C N9    1 
ATOM   308   C  C8    . G   A 1 15  ? 10.630  68.897  46.878  1.00 43.67  ? 515  G   C C8    1 
ATOM   309   N  N7    . G   A 1 15  ? 10.774  69.196  48.140  1.00 44.78  ? 515  G   C N7    1 
ATOM   310   C  C5    . G   A 1 15  ? 9.579   68.810  48.726  1.00 39.02  ? 515  G   C C5    1 
ATOM   311   C  C6    . G   A 1 15  ? 9.136   68.929  50.065  1.00 39.29  ? 515  G   C C6    1 
ATOM   312   O  O6    . G   A 1 15  ? 9.722   69.443  51.033  1.00 39.15  ? 515  G   C O6    1 
ATOM   313   N  N1    . G   A 1 15  ? 7.864   68.402  50.227  1.00 37.44  ? 515  G   C N1    1 
ATOM   314   C  C2    . G   A 1 15  ? 7.103   67.857  49.228  1.00 37.57  ? 515  G   C C2    1 
ATOM   315   N  N2    . G   A 1 15  ? 5.886   67.410  49.587  1.00 47.05  ? 515  G   C N2    1 
ATOM   316   N  N3    . G   A 1 15  ? 7.497   67.760  47.972  1.00 45.58  ? 515  G   C N3    1 
ATOM   317   C  C4    . G   A 1 15  ? 8.737   68.258  47.794  1.00 38.97  ? 515  G   C C4    1 
ATOM   318   P  P     . C   A 1 16  ? 7.009   69.395  41.155  1.00 83.49  ? 516  C   C P     1 
ATOM   319   O  OP1   . C   A 1 16  ? 5.634   68.987  40.775  1.00 83.95  ? 516  C   C OP1   1 
ATOM   320   O  OP2   . C   A 1 16  ? 8.088   69.419  40.122  1.00 85.39  ? 516  C   C OP2   1 
ATOM   321   O  "O5'" . C   A 1 16  ? 6.927   70.812  41.863  1.00 86.82  ? 516  C   C "O5'" 1 
ATOM   322   C  "C5'" . C   A 1 16  ? 6.487   71.947  41.146  1.00 89.77  ? 516  C   C "C5'" 1 
ATOM   323   C  "C4'" . C   A 1 16  ? 7.125   73.176  41.714  1.00 96.42  ? 516  C   C "C4'" 1 
ATOM   324   O  "O4'" . C   A 1 16  ? 8.570   73.082  41.592  1.00 104.77 ? 516  C   C "O4'" 1 
ATOM   325   C  "C3'" . C   A 1 16  ? 6.775   74.453  40.987  1.00 101.04 ? 516  C   C "C3'" 1 
ATOM   326   O  "O3'" . C   A 1 16  ? 5.532   74.934  41.477  1.00 94.48  ? 516  C   C "O3'" 1 
ATOM   327   C  "C2'" . C   A 1 16  ? 7.931   75.355  41.402  1.00 112.60 ? 516  C   C "C2'" 1 
ATOM   328   O  "O2'" . C   A 1 16  ? 7.779   75.844  42.723  1.00 121.42 ? 516  C   C "O2'" 1 
ATOM   329   C  "C1'" . C   A 1 16  ? 9.109   74.376  41.361  1.00 116.04 ? 516  C   C "C1'" 1 
ATOM   330   N  N1    . C   A 1 16  ? 9.811   74.378  40.060  1.00 125.59 ? 516  C   C N1    1 
ATOM   331   C  C2    . C   A 1 16  ? 10.788  75.373  39.802  1.00 126.62 ? 516  C   C C2    1 
ATOM   332   O  O2    . C   A 1 16  ? 11.054  76.210  40.683  1.00 123.78 ? 516  C   C O2    1 
ATOM   333   N  N3    . C   A 1 16  ? 11.415  75.387  38.599  1.00 124.91 ? 516  C   C N3    1 
ATOM   334   C  C4    . C   A 1 16  ? 11.114  74.464  37.677  1.00 125.32 ? 516  C   C C4    1 
ATOM   335   N  N4    . C   A 1 16  ? 11.756  74.515  36.506  1.00 122.89 ? 516  C   C N4    1 
ATOM   336   C  C5    . C   A 1 16  ? 10.140  73.445  37.915  1.00 126.25 ? 516  C   C C5    1 
ATOM   337   C  C6    . C   A 1 16  ? 9.520   73.439  39.107  1.00 127.24 ? 516  C   C C6    1 
ATOM   338   P  P     . G   A 1 17  ? 4.301   75.141  40.469  1.00 86.86  ? 518  G   C P     1 
ATOM   339   O  OP1   . G   A 1 17  ? 4.600   74.515  39.156  1.00 84.50  ? 518  G   C OP1   1 
ATOM   340   O  OP2   . G   A 1 17  ? 3.946   76.577  40.538  1.00 77.30  ? 518  G   C OP2   1 
ATOM   341   O  "O5'" . G   A 1 17  ? 3.131   74.328  41.164  1.00 78.63  ? 518  G   C "O5'" 1 
ATOM   342   C  "C5'" . G   A 1 17  ? 2.489   74.857  42.304  1.00 81.18  ? 518  G   C "C5'" 1 
ATOM   343   C  "C4'" . G   A 1 17  ? 1.434   73.907  42.794  1.00 84.52  ? 518  G   C "C4'" 1 
ATOM   344   O  "O4'" . G   A 1 17  ? 0.506   74.689  43.590  1.00 81.92  ? 518  G   C "O4'" 1 
ATOM   345   C  "C3'" . G   A 1 17  ? 0.599   73.318  41.668  1.00 85.59  ? 518  G   C "C3'" 1 
ATOM   346   O  "O3'" . G   A 1 17  ? 0.682   71.925  41.312  1.00 83.41  ? 518  G   C "O3'" 1 
ATOM   347   C  "C2'" . G   A 1 17  ? -0.649  74.177  41.537  1.00 82.01  ? 518  G   C "C2'" 1 
ATOM   348   O  "O2'" . G   A 1 17  ? -1.824  73.434  41.313  1.00 93.39  ? 518  G   C "O2'" 1 
ATOM   349   C  "C1'" . G   A 1 17  ? -0.723  74.842  42.909  1.00 80.95  ? 518  G   C "C1'" 1 
ATOM   350   N  N9    . G   A 1 17  ? -1.057  76.258  42.855  1.00 81.25  ? 518  G   C N9    1 
ATOM   351   C  C8    . G   A 1 17  ? -0.663  77.180  41.916  1.00 79.89  ? 518  G   C C8    1 
ATOM   352   N  N7    . G   A 1 17  ? -1.185  78.359  42.111  1.00 76.13  ? 518  G   C N7    1 
ATOM   353   C  C5    . G   A 1 17  ? -1.963  78.203  43.251  1.00 81.02  ? 518  G   C C5    1 
ATOM   354   C  C6    . G   A 1 17  ? -2.789  79.127  43.933  1.00 83.34  ? 518  G   C C6    1 
ATOM   355   O  O6    . G   A 1 17  ? -3.030  80.306  43.643  1.00 92.97  ? 518  G   C O6    1 
ATOM   356   N  N1    . G   A 1 17  ? -3.378  78.555  45.055  1.00 75.50  ? 518  G   C N1    1 
ATOM   357   C  C2    . G   A 1 17  ? -3.207  77.256  45.461  1.00 71.89  ? 518  G   C C2    1 
ATOM   358   N  N2    . G   A 1 17  ? -3.835  76.889  46.577  1.00 66.48  ? 518  G   C N2    1 
ATOM   359   N  N3    . G   A 1 17  ? -2.465  76.380  44.819  1.00 76.75  ? 518  G   C N3    1 
ATOM   360   C  C4    . G   A 1 17  ? -1.874  76.919  43.732  1.00 81.82  ? 518  G   C C4    1 
ATOM   361   P  P     . G   A 1 18  ? 0.444   70.769  42.424  1.00 77.30  ? 519  G   C P     1 
ATOM   362   O  OP1   . G   A 1 18  ? 1.339   71.007  43.588  1.00 85.01  ? 519  G   C OP1   1 
ATOM   363   O  OP2   . G   A 1 18  ? 0.508   69.479  41.700  1.00 89.43  ? 519  G   C OP2   1 
ATOM   364   O  "O5'" . G   A 1 18  ? -1.051  70.908  42.949  1.00 83.57  ? 519  G   C "O5'" 1 
ATOM   365   C  "C5'" . G   A 1 18  ? -1.348  70.707  44.333  1.00 77.98  ? 519  G   C "C5'" 1 
ATOM   366   C  "C4'" . G   A 1 18  ? -2.356  69.587  44.519  1.00 80.94  ? 519  G   C "C4'" 1 
ATOM   367   O  "O4'" . G   A 1 18  ? -3.639  69.968  43.960  1.00 82.35  ? 519  G   C "O4'" 1 
ATOM   368   C  "C3'" . G   A 1 18  ? -1.989  68.296  43.816  1.00 79.37  ? 519  G   C "C3'" 1 
ATOM   369   O  "O3'" . G   A 1 18  ? -1.746  67.167  44.653  1.00 79.37  ? 519  G   C "O3'" 1 
ATOM   370   C  "C2'" . G   A 1 18  ? -2.767  68.258  42.498  1.00 79.39  ? 519  G   C "C2'" 1 
ATOM   371   O  "O2'" . G   A 1 18  ? -3.335  66.997  42.194  1.00 72.16  ? 519  G   C "O2'" 1 
ATOM   372   C  "C1'" . G   A 1 18  ? -3.914  69.229  42.778  1.00 79.77  ? 519  G   C "C1'" 1 
ATOM   373   N  N9    . G   A 1 18  ? -4.227  70.177  41.714  1.00 79.01  ? 519  G   C N9    1 
ATOM   374   C  C8    . G   A 1 18  ? -3.547  70.394  40.541  1.00 77.71  ? 519  G   C C8    1 
ATOM   375   N  N7    . G   A 1 18  ? -4.067  71.352  39.817  1.00 76.05  ? 519  G   C N7    1 
ATOM   376   C  C5    . G   A 1 18  ? -5.162  71.787  40.556  1.00 77.41  ? 519  G   C C5    1 
ATOM   377   C  C6    . G   A 1 18  ? -6.110  72.819  40.295  1.00 72.20  ? 519  G   C C6    1 
ATOM   378   O  O6    . G   A 1 18  ? -6.158  73.598  39.341  1.00 69.98  ? 519  G   C O6    1 
ATOM   379   N  N1    . G   A 1 18  ? -7.067  72.902  41.300  1.00 70.38  ? 519  G   C N1    1 
ATOM   380   C  C2    . G   A 1 18  ? -7.112  72.107  42.420  1.00 75.24  ? 519  G   C C2    1 
ATOM   381   N  N2    . G   A 1 18  ? -8.138  72.320  43.265  1.00 72.06  ? 519  G   C N2    1 
ATOM   382   N  N3    . G   A 1 18  ? -6.223  71.165  42.689  1.00 79.87  ? 519  G   C N3    1 
ATOM   383   C  C4    . G   A 1 18  ? -5.285  71.058  41.719  1.00 81.43  ? 519  G   C C4    1 
ATOM   384   P  P     . U   A 1 19  ? -2.981  66.322  45.243  1.00 73.97  ? 520  U   C P     1 
ATOM   385   O  OP1   . U   A 1 19  ? -4.211  66.647  44.482  1.00 79.42  ? 520  U   C OP1   1 
ATOM   386   O  OP2   . U   A 1 19  ? -2.966  66.468  46.720  1.00 57.21  ? 520  U   C OP2   1 
ATOM   387   O  "O5'" . U   A 1 19  ? -2.584  64.818  44.933  1.00 67.27  ? 520  U   C "O5'" 1 
ATOM   388   C  "C5'" . U   A 1 19  ? -2.157  64.423  43.639  1.00 65.42  ? 520  U   C "C5'" 1 
ATOM   389   C  "C4'" . U   A 1 19  ? -1.038  63.431  43.766  1.00 65.66  ? 520  U   C "C4'" 1 
ATOM   390   O  "O4'" . U   A 1 19  ? 0.200   64.120  44.046  1.00 64.94  ? 520  U   C "O4'" 1 
ATOM   391   C  "C3'" . U   A 1 19  ? -1.211  62.476  44.929  1.00 66.21  ? 520  U   C "C3'" 1 
ATOM   392   O  "O3'" . U   A 1 19  ? -2.062  61.407  44.522  1.00 72.67  ? 520  U   C "O3'" 1 
ATOM   393   C  "C2'" . U   A 1 19  ? 0.227   62.044  45.226  1.00 65.55  ? 520  U   C "C2'" 1 
ATOM   394   O  "O2'" . U   A 1 19  ? 0.643   60.957  44.428  1.00 70.43  ? 520  U   C "O2'" 1 
ATOM   395   C  "C1'" . U   A 1 19  ? 1.029   63.296  44.842  1.00 57.59  ? 520  U   C "C1'" 1 
ATOM   396   N  N1    . U   A 1 19  ? 1.545   64.105  45.955  1.00 55.28  ? 520  U   C N1    1 
ATOM   397   C  C2    . U   A 1 19  ? 2.918   64.234  46.063  1.00 60.86  ? 520  U   C C2    1 
ATOM   398   O  O2    . U   A 1 19  ? 3.695   63.714  45.281  1.00 66.36  ? 520  U   C O2    1 
ATOM   399   N  N3    . U   A 1 19  ? 3.347   64.998  47.113  1.00 56.81  ? 520  U   C N3    1 
ATOM   400   C  C4    . U   A 1 19  ? 2.565   65.639  48.046  1.00 55.42  ? 520  U   C C4    1 
ATOM   401   O  O4    . U   A 1 19  ? 3.106   66.311  48.927  1.00 44.96  ? 520  U   C O4    1 
ATOM   402   C  C5    . U   A 1 19  ? 1.157   65.455  47.870  1.00 53.27  ? 520  U   C C5    1 
ATOM   403   C  C6    . U   A 1 19  ? 0.709   64.713  46.855  1.00 53.76  ? 520  U   C C6    1 
ATOM   404   P  P     . U   A 1 20  A -3.355  61.024  45.412  1.00 66.98  ? 520  U   C P     1 
ATOM   405   O  OP1   . U   A 1 20  A -4.107  59.989  44.658  1.00 72.07  ? 520  U   C OP1   1 
ATOM   406   O  OP2   . U   A 1 20  A -4.049  62.263  45.839  1.00 73.51  ? 520  U   C OP2   1 
ATOM   407   O  "O5'" . U   A 1 20  A -2.715  60.344  46.704  1.00 71.65  ? 520  U   C "O5'" 1 
ATOM   408   C  "C5'" . U   A 1 20  A -3.395  60.322  47.951  1.00 55.39  ? 520  U   C "C5'" 1 
ATOM   409   C  "C4'" . U   A 1 20  A -2.676  59.398  48.909  1.00 55.21  ? 520  U   C "C4'" 1 
ATOM   410   O  "O4'" . U   A 1 20  A -2.658  58.063  48.348  1.00 53.24  ? 520  U   C "O4'" 1 
ATOM   411   C  "C3'" . U   A 1 20  A -1.214  59.733  49.171  1.00 53.79  ? 520  U   C "C3'" 1 
ATOM   412   O  "O3'" . U   A 1 20  A -1.126  60.658  50.257  1.00 52.38  ? 520  U   C "O3'" 1 
ATOM   413   C  "C2'" . U   A 1 20  A -0.611  58.376  49.543  1.00 48.72  ? 520  U   C "C2'" 1 
ATOM   414   O  "O2'" . U   A 1 20  A -0.772  58.048  50.906  1.00 50.57  ? 520  U   C "O2'" 1 
ATOM   415   C  "C1'" . U   A 1 20  A -1.451  57.412  48.701  1.00 49.56  ? 520  U   C "C1'" 1 
ATOM   416   N  N1    . U   A 1 20  A -0.814  56.940  47.468  1.00 45.14  ? 520  U   C N1    1 
ATOM   417   C  C2    . U   A 1 20  A 0.096   55.914  47.577  1.00 42.99  ? 520  U   C C2    1 
ATOM   418   O  O2    . U   A 1 20  A 0.407   55.429  48.651  1.00 48.56  ? 520  U   C O2    1 
ATOM   419   N  N3    . U   A 1 20  A 0.628   55.482  46.389  1.00 31.87  ? 520  U   C N3    1 
ATOM   420   C  C4    . U   A 1 20  A 0.349   55.980  45.121  1.00 50.67  ? 520  U   C C4    1 
ATOM   421   O  O4    . U   A 1 20  A 0.900   55.483  44.132  1.00 52.35  ? 520  U   C O4    1 
ATOM   422   C  C5    . U   A 1 20  A -0.594  57.059  45.098  1.00 50.35  ? 520  U   C C5    1 
ATOM   423   C  C6    . U   A 1 20  A -1.130  57.492  46.243  1.00 52.23  ? 520  U   C C6    1 
ATOM   424   P  P     . A   A 1 21  ? -0.382  62.061  50.047  1.00 54.37  ? 521  A   C P     1 
ATOM   425   O  OP1   . A   A 1 21  ? -0.711  63.007  51.135  1.00 56.69  ? 521  A   C OP1   1 
ATOM   426   O  OP2   . A   A 1 21  ? -0.643  62.439  48.641  1.00 46.60  ? 521  A   C OP2   1 
ATOM   427   O  "O5'" . A   A 1 21  ? 1.164   61.696  50.204  1.00 62.87  ? 521  A   C "O5'" 1 
ATOM   428   C  "C5'" . A   A 1 21  ? 1.927   61.292  49.078  1.00 53.32  ? 521  A   C "C5'" 1 
ATOM   429   C  "C4'" . A   A 1 21  ? 3.264   61.995  49.064  1.00 53.43  ? 521  A   C "C4'" 1 
ATOM   430   O  "O4'" . A   A 1 21  ? 3.114   63.321  49.646  1.00 45.70  ? 521  A   C "O4'" 1 
ATOM   431   C  "C3'" . A   A 1 21  ? 4.381   61.413  49.915  1.00 44.57  ? 521  A   C "C3'" 1 
ATOM   432   O  "O3'" . A   A 1 21  ? 4.972   60.296  49.278  1.00 34.52  ? 521  A   C "O3'" 1 
ATOM   433   C  "C2'" . A   A 1 21  ? 5.337   62.598  49.947  1.00 47.06  ? 521  A   C "C2'" 1 
ATOM   434   O  "O2'" . A   A 1 21  ? 5.952   62.851  48.695  1.00 34.48  ? 521  A   C "O2'" 1 
ATOM   435   C  "C1'" . A   A 1 21  ? 4.356   63.737  50.195  1.00 41.44  ? 521  A   C "C1'" 1 
ATOM   436   N  N9    . A   A 1 21  ? 4.177   64.000  51.616  1.00 40.04  ? 521  A   C N9    1 
ATOM   437   C  C8    . A   A 1 21  ? 3.105   63.712  52.407  1.00 44.96  ? 521  A   C C8    1 
ATOM   438   N  N7    . A   A 1 21  ? 3.231   64.133  53.641  1.00 46.97  ? 521  A   C N7    1 
ATOM   439   C  C5    . A   A 1 21  ? 4.481   64.729  53.662  1.00 43.65  ? 521  A   C C5    1 
ATOM   440   C  C6    . A   A 1 21  ? 5.213   65.376  54.685  1.00 56.63  ? 521  A   C C6    1 
ATOM   441   N  N6    . A   A 1 21  ? 4.756   65.575  55.935  1.00 49.37  ? 521  A   C N6    1 
ATOM   442   N  N1    . A   A 1 21  ? 6.450   65.826  54.372  1.00 51.02  ? 521  A   C N1    1 
ATOM   443   C  C2    . A   A 1 21  ? 6.899   65.649  53.121  1.00 40.79  ? 521  A   C C2    1 
ATOM   444   N  N3    . A   A 1 21  ? 6.302   65.075  52.085  1.00 40.26  ? 521  A   C N3    1 
ATOM   445   C  C4    . A   A 1 21  ? 5.083   64.632  52.426  1.00 42.36  ? 521  A   C C4    1 
ATOM   446   P  P     . G   A 1 22  ? 5.157   58.913  50.087  1.00 41.26  ? 522  G   C P     1 
ATOM   447   O  OP1   . G   A 1 22  ? 3.929   58.097  49.878  1.00 50.51  ? 522  G   C OP1   1 
ATOM   448   O  OP2   . G   A 1 22  ? 5.614   59.192  51.480  1.00 37.03  ? 522  G   C OP2   1 
ATOM   449   O  "O5'" . G   A 1 22  ? 6.322   58.209  49.274  1.00 34.87  ? 522  G   C "O5'" 1 
ATOM   450   C  "C5'" . G   A 1 22  ? 6.106   57.786  47.927  1.00 39.30  ? 522  G   C "C5'" 1 
ATOM   451   C  "C4'" . G   A 1 22  ? 7.343   58.029  47.102  1.00 42.35  ? 522  G   C "C4'" 1 
ATOM   452   O  "O4'" . G   A 1 22  ? 7.532   59.466  46.936  1.00 47.81  ? 522  G   C "O4'" 1 
ATOM   453   C  "C3'" . G   A 1 22  ? 8.647   57.586  47.746  1.00 40.06  ? 522  G   C "C3'" 1 
ATOM   454   O  "O3'" . G   A 1 22  ? 8.893   56.190  47.680  1.00 36.73  ? 522  G   C "O3'" 1 
ATOM   455   C  "C2'" . G   A 1 22  ? 9.655   58.432  46.983  1.00 46.44  ? 522  G   C "C2'" 1 
ATOM   456   O  "O2'" . G   A 1 22  ? 9.904   57.979  45.664  1.00 44.80  ? 522  G   C "O2'" 1 
ATOM   457   C  "C1'" . G   A 1 22  ? 8.921   59.774  46.960  1.00 43.00  ? 522  G   C "C1'" 1 
ATOM   458   N  N9    . G   A 1 22  ? 9.202   60.515  48.190  1.00 49.87  ? 522  G   C N9    1 
ATOM   459   C  C8    . G   A 1 22  ? 8.365   60.717  49.260  1.00 38.59  ? 522  G   C C8    1 
ATOM   460   N  N7    . G   A 1 22  ? 8.915   61.426  50.212  1.00 43.71  ? 522  G   C N7    1 
ATOM   461   C  C5    . G   A 1 22  ? 10.190  61.706  49.741  1.00 42.85  ? 522  G   C C5    1 
ATOM   462   C  C6    . G   A 1 22  ? 11.263  62.435  50.330  1.00 35.59  ? 522  G   C C6    1 
ATOM   463   O  O6    . G   A 1 22  ? 11.305  63.027  51.410  1.00 39.68  ? 522  G   C O6    1 
ATOM   464   N  N1    . G   A 1 22  ? 12.376  62.433  49.518  1.00 33.26  ? 522  G   C N1    1 
ATOM   465   C  C2    . G   A 1 22  ? 12.469  61.822  48.304  1.00 30.75  ? 522  G   C C2    1 
ATOM   466   N  N2    . G   A 1 22  ? 13.644  61.911  47.686  1.00 31.58  ? 522  G   C N2    1 
ATOM   467   N  N3    . G   A 1 22  ? 11.489  61.163  47.737  1.00 40.01  ? 522  G   C N3    1 
ATOM   468   C  C4    . G   A 1 22  ? 10.385  61.142  48.503  1.00 42.56  ? 522  G   C C4    1 
ATOM   469   P  P     . G   A 1 23  ? 9.651   55.476  48.906  1.00 46.60  ? 523  G   C P     1 
ATOM   470   O  OP1   . G   A 1 23  ? 9.363   54.025  48.871  1.00 49.53  ? 523  G   C OP1   1 
ATOM   471   O  OP2   . G   A 1 23  ? 9.328   56.262  50.128  1.00 32.79  ? 523  G   C OP2   1 
ATOM   472   O  "O5'" . G   A 1 23  ? 11.188  55.667  48.546  1.00 48.05  ? 523  G   C "O5'" 1 
ATOM   473   C  "C5'" . G   A 1 23  ? 11.631  55.476  47.205  1.00 40.39  ? 523  G   C "C5'" 1 
ATOM   474   C  "C4'" . G   A 1 23  ? 13.010  56.053  47.027  1.00 42.56  ? 523  G   C "C4'" 1 
ATOM   475   O  "O4'" . G   A 1 23  ? 12.965  57.507  47.112  1.00 47.83  ? 523  G   C "O4'" 1 
ATOM   476   C  "C3'" . G   A 1 23  ? 14.018  55.662  48.095  1.00 39.49  ? 523  G   C "C3'" 1 
ATOM   477   O  "O3'" . G   A 1 23  ? 14.577  54.371  47.844  1.00 45.29  ? 523  G   C "O3'" 1 
ATOM   478   C  "C2'" . G   A 1 23  ? 15.057  56.752  47.903  1.00 42.07  ? 523  G   C "C2'" 1 
ATOM   479   O  "O2'" . G   A 1 23  ? 15.790  56.525  46.712  1.00 41.38  ? 523  G   C "O2'" 1 
ATOM   480   C  "C1'" . G   A 1 23  ? 14.165  57.980  47.712  1.00 39.12  ? 523  G   C "C1'" 1 
ATOM   481   N  N9    . G   A 1 23  ? 13.837  58.620  48.983  1.00 40.65  ? 523  G   C N9    1 
ATOM   482   C  C8    . G   A 1 23  ? 12.658  58.515  49.682  1.00 42.74  ? 523  G   C C8    1 
ATOM   483   N  N7    . G   A 1 23  ? 12.663  59.188  50.798  1.00 41.11  ? 523  G   C N7    1 
ATOM   484   C  C5    . G   A 1 23  ? 13.920  59.782  50.841  1.00 46.06  ? 523  G   C C5    1 
ATOM   485   C  C6    . G   A 1 23  ? 14.512  60.636  51.825  1.00 41.72  ? 523  G   C C6    1 
ATOM   486   O  O6    . G   A 1 23  ? 14.019  61.069  52.870  1.00 37.51  ? 523  G   C O6    1 
ATOM   487   N  N1    . G   A 1 23  ? 15.814  60.979  51.488  1.00 39.26  ? 523  G   C N1    1 
ATOM   488   C  C2    . G   A 1 23  ? 16.467  60.574  50.351  1.00 49.38  ? 523  G   C C2    1 
ATOM   489   N  N2    . G   A 1 23  ? 17.730  61.014  50.210  1.00 39.11  ? 523  G   C N2    1 
ATOM   490   N  N3    . G   A 1 23  ? 15.928  59.795  49.421  1.00 47.46  ? 523  G   C N3    1 
ATOM   491   C  C4    . G   A 1 23  ? 14.660  59.439  49.730  1.00 43.04  ? 523  G   C C4    1 
ATOM   492   P  P     . A   A 1 24  ? 15.072  53.462  49.077  1.00 43.09  ? 524  A   C P     1 
ATOM   493   O  OP1   . A   A 1 24  ? 15.459  52.139  48.549  1.00 48.89  ? 524  A   C OP1   1 
ATOM   494   O  OP2   . A   A 1 24  ? 14.047  53.560  50.143  1.00 50.64  ? 524  A   C OP2   1 
ATOM   495   O  "O5'" . A   A 1 24  ? 16.373  54.196  49.628  1.00 47.70  ? 524  A   C "O5'" 1 
ATOM   496   C  "C5'" . A   A 1 24  ? 17.549  54.297  48.832  1.00 39.31  ? 524  A   C "C5'" 1 
ATOM   497   C  "C4'" . A   A 1 24  ? 18.584  55.138  49.540  1.00 40.42  ? 524  A   C "C4'" 1 
ATOM   498   O  "O4'" . A   A 1 24  ? 18.105  56.509  49.655  1.00 40.23  ? 524  A   C "O4'" 1 
ATOM   499   C  "C3'" . A   A 1 24  ? 18.888  54.740  50.971  1.00 32.28  ? 524  A   C "C3'" 1 
ATOM   500   O  "O3'" . A   A 1 24  ? 19.821  53.673  51.031  1.00 35.80  ? 524  A   C "O3'" 1 
ATOM   501   C  "C2'" . A   A 1 24  ? 19.466  56.037  51.531  1.00 44.70  ? 524  A   C "C2'" 1 
ATOM   502   O  "O2'" . A   A 1 24  ? 20.799  56.293  51.137  1.00 45.42  ? 524  A   C "O2'" 1 
ATOM   503   C  "C1'" . A   A 1 24  ? 18.565  57.076  50.869  1.00 34.09  ? 524  A   C "C1'" 1 
ATOM   504   N  N9    . A   A 1 24  ? 17.413  57.394  51.711  1.00 42.12  ? 524  A   C N9    1 
ATOM   505   C  C8    . A   A 1 24  ? 16.103  56.989  51.574  1.00 43.25  ? 524  A   C C8    1 
ATOM   506   N  N7    . A   A 1 24  ? 15.307  57.445  52.513  1.00 36.92  ? 524  A   C N7    1 
ATOM   507   C  C5    . A   A 1 24  ? 16.148  58.207  53.317  1.00 40.08  ? 524  A   C C5    1 
ATOM   508   C  C6    . A   A 1 24  ? 15.916  58.963  54.471  1.00 34.79  ? 524  A   C C6    1 
ATOM   509   N  N6    . A   A 1 24  ? 14.727  59.080  55.050  1.00 43.05  ? 524  A   C N6    1 
ATOM   510   N  N1    . A   A 1 24  ? 16.967  59.608  55.022  1.00 49.85  ? 524  A   C N1    1 
ATOM   511   C  C2    . A   A 1 24  ? 18.170  59.489  54.449  1.00 39.04  ? 524  A   C C2    1 
ATOM   512   N  N3    . A   A 1 24  ? 18.516  58.804  53.368  1.00 44.66  ? 524  A   C N3    1 
ATOM   513   C  C4    . A   A 1 24  ? 17.445  58.181  52.838  1.00 39.48  ? 524  A   C C4    1 
ATOM   514   P  P     . C   A 1 25  ? 19.833  52.705  52.313  1.00 41.31  ? 525  C   C P     1 
ATOM   515   O  OP1   . C   A 1 25  ? 20.702  51.512  52.075  1.00 36.09  ? 525  C   C OP1   1 
ATOM   516   O  OP2   . C   A 1 25  ? 18.413  52.514  52.650  1.00 46.11  ? 525  C   C OP2   1 
ATOM   517   O  "O5'" . C   A 1 25  ? 20.523  53.567  53.461  1.00 36.46  ? 525  C   C "O5'" 1 
ATOM   518   C  "C5'" . C   A 1 25  ? 21.882  53.972  53.342  1.00 29.54  ? 525  C   C "C5'" 1 
ATOM   519   C  "C4'" . C   A 1 25  ? 22.283  54.793  54.540  1.00 38.47  ? 525  C   C "C4'" 1 
ATOM   520   O  "O4'" . C   A 1 25  ? 21.549  56.053  54.571  1.00 34.89  ? 525  C   C "O4'" 1 
ATOM   521   C  "C3'" . C   A 1 25  ? 21.986  54.140  55.875  1.00 35.05  ? 525  C   C "C3'" 1 
ATOM   522   O  "O3'" . C   A 1 25  ? 23.041  53.269  56.247  1.00 43.62  ? 525  C   C "O3'" 1 
ATOM   523   C  "C2'" . C   A 1 25  ? 21.896  55.337  56.811  1.00 25.65  ? 525  C   C "C2'" 1 
ATOM   524   O  "O2'" . C   A 1 25  ? 23.138  55.813  57.243  1.00 34.35  ? 525  C   C "O2'" 1 
ATOM   525   C  "C1'" . C   A 1 25  ? 21.227  56.375  55.919  1.00 37.83  ? 525  C   C "C1'" 1 
ATOM   526   N  N1    . C   A 1 25  ? 19.758  56.360  56.079  1.00 41.36  ? 525  C   C N1    1 
ATOM   527   C  C2    . C   A 1 25  ? 19.211  56.941  57.217  1.00 32.07  ? 525  C   C C2    1 
ATOM   528   O  O2    . C   A 1 25  ? 19.977  57.418  58.063  1.00 31.40  ? 525  C   C O2    1 
ATOM   529   N  N3    . C   A 1 25  ? 17.869  56.969  57.374  1.00 43.39  ? 525  C   C N3    1 
ATOM   530   C  C4    . C   A 1 25  ? 17.082  56.432  56.440  1.00 53.36  ? 525  C   C C4    1 
ATOM   531   N  N4    . C   A 1 25  ? 15.759  56.491  56.622  1.00 51.14  ? 525  C   C N4    1 
ATOM   532   C  C5    . C   A 1 25  ? 17.616  55.811  55.270  1.00 56.03  ? 525  C   C C5    1 
ATOM   533   C  C6    . C   A 1 25  ? 18.949  55.800  55.132  1.00 43.33  ? 525  C   C C6    1 
ATOM   534   P  P     . G   A 1 26  ? 22.721  51.946  57.089  1.00 43.54  ? 526  G   C P     1 
ATOM   535   O  OP1   . G   A 1 26  ? 23.998  51.296  57.459  1.00 47.61  ? 526  G   C OP1   1 
ATOM   536   O  OP2   . G   A 1 26  ? 21.684  51.191  56.318  1.00 36.15  ? 526  G   C OP2   1 
ATOM   537   O  "O5'" . G   A 1 26  ? 22.080  52.492  58.436  1.00 37.50  ? 526  G   C "O5'" 1 
ATOM   538   C  "C5'" . G   A 1 26  ? 22.856  53.207  59.377  1.00 38.21  ? 526  G   C "C5'" 1 
ATOM   539   C  "C4'" . G   A 1 26  ? 21.957  53.789  60.435  1.00 42.85  ? 526  G   C "C4'" 1 
ATOM   540   O  "O4'" . G   A 1 26  ? 21.080  54.778  59.831  1.00 37.59  ? 526  G   C "O4'" 1 
ATOM   541   C  "C3'" . G   A 1 26  ? 20.978  52.805  61.064  1.00 41.87  ? 526  G   C "C3'" 1 
ATOM   542   O  "O3'" . G   A 1 26  ? 21.580  52.040  62.094  1.00 55.44  ? 526  G   C "O3'" 1 
ATOM   543   C  "C2'" . G   A 1 26  ? 19.940  53.749  61.624  1.00 38.82  ? 526  G   C "C2'" 1 
ATOM   544   O  "O2'" . G   A 1 26  ? 20.414  54.433  62.754  1.00 34.19  ? 526  G   C "O2'" 1 
ATOM   545   C  "C1'" . G   A 1 26  ? 19.815  54.747  60.477  1.00 42.69  ? 526  G   C "C1'" 1 
ATOM   546   N  N9    . G   A 1 26  ? 18.798  54.328  59.516  1.00 43.37  ? 526  G   C N9    1 
ATOM   547   C  C8    . G   A 1 26  ? 18.993  53.729  58.298  1.00 41.98  ? 526  G   C C8    1 
ATOM   548   N  N7    . G   A 1 26  ? 17.877  53.493  57.660  1.00 39.83  ? 526  G   C N7    1 
ATOM   549   C  C5    . G   A 1 26  ? 16.890  53.961  58.513  1.00 36.41  ? 526  G   C C5    1 
ATOM   550   C  C6    . G   A 1 26  ? 15.480  53.969  58.370  1.00 37.55  ? 526  G   C C6    1 
ATOM   551   O  O6    . G   A 1 26  ? 14.789  53.539  57.429  1.00 39.63  ? 526  G   C O6    1 
ATOM   552   N  N1    . G   A 1 26  ? 14.864  54.540  59.470  1.00 34.93  ? 526  G   C N1    1 
ATOM   553   C  C2    . G   A 1 26  ? 15.509  55.022  60.571  1.00 43.16  ? 526  G   C C2    1 
ATOM   554   N  N2    . G   A 1 26  ? 14.734  55.554  61.521  1.00 53.28  ? 526  G   C N2    1 
ATOM   555   N  N3    . G   A 1 26  ? 16.819  54.995  60.732  1.00 49.67  ? 526  G   C N3    1 
ATOM   556   C  C4    . G   A 1 26  ? 17.442  54.466  59.666  1.00 41.66  ? 526  G   C C4    1 
ATOM   557   P  P     . C   A 1 27  ? 21.073  50.538  62.377  1.00 59.15  ? 527  C   C P     1 
ATOM   558   O  OP1   . C   A 1 27  ? 21.900  50.033  63.500  1.00 48.46  ? 527  C   C OP1   1 
ATOM   559   O  OP2   . C   A 1 27  ? 21.019  49.784  61.098  1.00 42.05  ? 527  C   C OP2   1 
ATOM   560   O  "O5'" . C   A 1 27  ? 19.582  50.740  62.895  1.00 48.60  ? 527  C   C "O5'" 1 
ATOM   561   C  "C5'" . C   A 1 27  ? 19.346  51.397  64.130  1.00 52.78  ? 527  C   C "C5'" 1 
ATOM   562   C  "C4'" . C   A 1 27  ? 17.872  51.426  64.439  1.00 56.49  ? 527  C   C "C4'" 1 
ATOM   563   O  "O4'" . C   A 1 27  ? 17.207  52.307  63.505  1.00 50.01  ? 527  C   C "O4'" 1 
ATOM   564   C  "C3'" . C   A 1 27  ? 17.120  50.112  64.291  1.00 61.05  ? 527  C   C "C3'" 1 
ATOM   565   O  "O3'" . C   A 1 27  ? 17.315  49.286  65.435  1.00 65.72  ? 527  C   C "O3'" 1 
ATOM   566   C  "C2'" . C   A 1 27  ? 15.690  50.618  64.167  1.00 58.01  ? 527  C   C "C2'" 1 
ATOM   567   O  "O2'" . C   A 1 27  ? 15.192  51.093  65.404  1.00 53.54  ? 527  C   C "O2'" 1 
ATOM   568   C  "C1'" . C   A 1 27  ? 15.898  51.827  63.253  1.00 56.36  ? 527  C   C "C1'" 1 
ATOM   569   N  N1    . C   A 1 27  ? 15.800  51.489  61.829  1.00 44.36  ? 527  C   C N1    1 
ATOM   570   C  C2    . C   A 1 27  ? 14.547  51.460  61.256  1.00 49.23  ? 527  C   C C2    1 
ATOM   571   O  O2    . C   A 1 27  ? 13.567  51.724  61.969  1.00 56.53  ? 527  C   C O2    1 
ATOM   572   N  N3    . C   A 1 27  ? 14.421  51.139  59.949  1.00 46.54  ? 527  C   C N3    1 
ATOM   573   C  C4    . C   A 1 27  ? 15.505  50.829  59.231  1.00 47.38  ? 527  C   C C4    1 
ATOM   574   N  N4    . C   A 1 27  ? 15.325  50.466  57.952  1.00 30.70  ? 527  C   C N4    1 
ATOM   575   C  C5    . C   A 1 27  ? 16.814  50.864  59.795  1.00 29.98  ? 527  C   C C5    1 
ATOM   576   C  C6    . C   A 1 27  ? 16.911  51.202  61.087  1.00 43.44  ? 527  C   C C6    1 
ATOM   577   P  P     . G   A 1 28  ? 17.491  47.693  65.254  1.00 67.39  ? 528  G   C P     1 
ATOM   578   O  OP1   . G   A 1 28  ? 17.989  47.177  66.561  1.00 53.42  ? 528  G   C OP1   1 
ATOM   579   O  OP2   . G   A 1 28  ? 18.249  47.391  64.007  1.00 57.15  ? 528  G   C OP2   1 
ATOM   580   O  "O5'" . G   A 1 28  ? 16.002  47.192  64.996  1.00 63.98  ? 528  G   C "O5'" 1 
ATOM   581   C  "C5'" . G   A 1 28  ? 14.968  47.441  65.945  1.00 60.78  ? 528  G   C "C5'" 1 
ATOM   582   C  "C4'" . G   A 1 28  ? 13.617  47.061  65.371  1.00 51.89  ? 528  G   C "C4'" 1 
ATOM   583   O  "O4'" . G   A 1 28  ? 13.236  47.997  64.323  1.00 50.63  ? 528  G   C "O4'" 1 
ATOM   584   C  "C3'" . G   A 1 28  ? 13.506  45.709  64.681  1.00 57.01  ? 528  G   C "C3'" 1 
ATOM   585   O  "O3'" . G   A 1 28  ? 13.416  44.618  65.599  1.00 66.79  ? 528  G   C "O3'" 1 
ATOM   586   C  "C2'" . G   A 1 28  ? 12.226  45.889  63.874  1.00 56.50  ? 528  G   C "C2'" 1 
ATOM   587   O  "O2'" . G   A 1 28  ? 11.061  45.780  64.674  1.00 58.07  ? 528  G   C "O2'" 1 
ATOM   588   C  "C1'" . G   A 1 28  ? 12.379  47.337  63.394  1.00 56.03  ? 528  G   C "C1'" 1 
ATOM   589   N  N9    . G   A 1 28  ? 12.974  47.425  62.063  1.00 45.79  ? 528  G   C N9    1 
ATOM   590   C  C8    . G   A 1 28  ? 14.254  47.825  61.752  1.00 50.96  ? 528  G   C C8    1 
ATOM   591   N  N7    . G   A 1 28  ? 14.507  47.783  60.471  1.00 43.46  ? 528  G   C N7    1 
ATOM   592   C  C5    . G   A 1 28  ? 13.321  47.342  59.900  1.00 44.19  ? 528  G   C C5    1 
ATOM   593   C  C6    . G   A 1 28  ? 12.981  47.122  58.535  1.00 55.00  ? 528  G   C C6    1 
ATOM   594   O  O6    . G   A 1 28  ? 13.680  47.294  57.526  1.00 50.07  ? 528  G   C O6    1 
ATOM   595   N  N1    . G   A 1 28  ? 11.673  46.664  58.401  1.00 51.78  ? 528  G   C N1    1 
ATOM   596   C  C2    . G   A 1 28  ? 10.804  46.451  59.438  1.00 52.24  ? 528  G   C C2    1 
ATOM   597   N  N2    . G   A 1 28  ? 9.593   45.992  59.095  1.00 55.20  ? 528  G   C N2    1 
ATOM   598   N  N3    . G   A 1 28  ? 11.099  46.667  60.712  1.00 43.82  ? 528  G   C N3    1 
ATOM   599   C  C4    . G   A 1 28  ? 12.366  47.112  60.868  1.00 43.03  ? 528  G   C C4    1 
ATOM   600   P  P     . G   A 1 29  ? 13.932  43.154  65.154  1.00 73.29  ? 529  G   C P     1 
ATOM   601   O  OP1   . G   A 1 29  ? 13.891  42.290  66.355  1.00 86.38  ? 529  G   C OP1   1 
ATOM   602   O  OP2   . G   A 1 29  ? 15.197  43.289  64.395  1.00 79.33  ? 529  G   C OP2   1 
ATOM   603   O  "O5'" . G   A 1 29  ? 12.827  42.639  64.136  1.00 71.66  ? 529  G   C "O5'" 1 
ATOM   604   C  "C5'" . G   A 1 29  ? 11.509  42.378  64.590  1.00 70.82  ? 529  G   C "C5'" 1 
ATOM   605   C  "C4'" . G   A 1 29  ? 10.619  42.040  63.428  1.00 71.95  ? 529  G   C "C4'" 1 
ATOM   606   O  "O4'" . G   A 1 29  ? 10.536  43.185  62.540  1.00 73.79  ? 529  G   C "O4'" 1 
ATOM   607   C  "C3'" . G   A 1 29  ? 11.117  40.929  62.522  1.00 75.23  ? 529  G   C "C3'" 1 
ATOM   608   O  "O3'" . G   A 1 29  ? 10.826  39.647  63.057  1.00 80.92  ? 529  G   C "O3'" 1 
ATOM   609   C  "C2'" . G   A 1 29  ? 10.327  41.200  61.250  1.00 77.92  ? 529  G   C "C2'" 1 
ATOM   610   O  "O2'" . G   A 1 29  ? 8.984   40.760  61.332  1.00 81.25  ? 529  G   C "O2'" 1 
ATOM   611   C  "C1'" . G   A 1 29  ? 10.371  42.729  61.202  1.00 76.68  ? 529  G   C "C1'" 1 
ATOM   612   N  N9    . G   A 1 29  ? 11.491  43.209  60.397  1.00 64.47  ? 529  G   C N9    1 
ATOM   613   C  C8    . G   A 1 29  ? 12.648  43.805  60.840  1.00 64.52  ? 529  G   C C8    1 
ATOM   614   N  N7    . G   A 1 29  ? 13.474  44.099  59.873  1.00 60.20  ? 529  G   C N7    1 
ATOM   615   C  C5    . G   A 1 29  ? 12.820  43.676  58.722  1.00 61.03  ? 529  G   C C5    1 
ATOM   616   C  C6    . G   A 1 29  ? 13.225  43.727  57.350  1.00 61.18  ? 529  G   C C6    1 
ATOM   617   O  O6    . G   A 1 29  ? 14.276  44.170  56.867  1.00 59.89  ? 529  G   C O6    1 
ATOM   618   N  N1    . G   A 1 29  ? 12.255  43.183  56.513  1.00 57.88  ? 529  G   C N1    1 
ATOM   619   C  C2    . G   A 1 29  ? 11.058  42.656  56.934  1.00 56.21  ? 529  G   C C2    1 
ATOM   620   N  N2    . G   A 1 29  ? 10.268  42.178  55.971  1.00 58.71  ? 529  G   C N2    1 
ATOM   621   N  N3    . G   A 1 29  ? 10.668  42.603  58.202  1.00 51.26  ? 529  G   C N3    1 
ATOM   622   C  C4    . G   A 1 29  ? 11.592  43.127  59.033  1.00 58.16  ? 529  G   C C4    1 
ATOM   623   P  P     . C   A 1 30  ? 11.766  38.395  62.682  1.00 84.87  ? 530  C   C P     1 
ATOM   624   O  OP1   . C   A 1 30  ? 11.300  37.261  63.519  1.00 92.30  ? 530  C   C OP1   1 
ATOM   625   O  OP2   . C   A 1 30  ? 13.180  38.847  62.796  1.00 88.17  ? 530  C   C OP2   1 
ATOM   626   O  "O5'" . C   A 1 30  ? 11.417  38.083  61.154  1.00 62.17  ? 530  C   C "O5'" 1 
ATOM   627   C  "C5'" . C   A 1 30  ? 10.130  37.590  60.803  1.00 63.49  ? 530  C   C "C5'" 1 
ATOM   628   C  "C4'" . C   A 1 30  ? 9.971   37.514  59.303  1.00 69.91  ? 530  C   C "C4'" 1 
ATOM   629   O  "O4'" . C   A 1 30  ? 10.147  38.839  58.738  1.00 72.11  ? 530  C   C "O4'" 1 
ATOM   630   C  "C3'" . C   A 1 30  ? 10.951  36.635  58.534  1.00 71.64  ? 530  C   C "C3'" 1 
ATOM   631   O  "O3'" . C   A 1 30  ? 10.541  35.264  58.522  1.00 70.62  ? 530  C   C "O3'" 1 
ATOM   632   C  "C2'" . C   A 1 30  ? 10.882  37.243  57.137  1.00 67.83  ? 530  C   C "C2'" 1 
ATOM   633   O  "O2'" . C   A 1 30  ? 9.750   36.819  56.401  1.00 58.71  ? 530  C   C "O2'" 1 
ATOM   634   C  "C1'" . C   A 1 30  ? 10.769  38.733  57.468  1.00 67.96  ? 530  C   C "C1'" 1 
ATOM   635   N  N1    . C   A 1 30  ? 12.080  39.399  57.548  1.00 69.43  ? 530  C   C N1    1 
ATOM   636   C  C2    . C   A 1 30  ? 12.741  39.732  56.357  1.00 68.76  ? 530  C   C C2    1 
ATOM   637   O  O2    . C   A 1 30  ? 12.222  39.413  55.271  1.00 67.92  ? 530  C   C O2    1 
ATOM   638   N  N3    . C   A 1 30  ? 13.926  40.383  56.420  1.00 66.52  ? 530  C   C N3    1 
ATOM   639   C  C4    . C   A 1 30  ? 14.460  40.687  57.608  1.00 66.20  ? 530  C   C C4    1 
ATOM   640   N  N4    . C   A 1 30  ? 15.621  41.355  57.618  1.00 60.37  ? 530  C   C N4    1 
ATOM   641   C  C5    . C   A 1 30  ? 13.822  40.330  58.837  1.00 51.48  ? 530  C   C C5    1 
ATOM   642   C  C6    . C   A 1 30  ? 12.644  39.698  58.760  1.00 59.99  ? 530  C   C C6    1 
ATOM   643   P  P     . C   A 1 31  ? 11.641  34.090  58.346  1.00 73.94  ? 531  C   C P     1 
ATOM   644   O  OP1   . C   A 1 31  ? 10.918  32.794  58.462  1.00 72.44  ? 531  C   C OP1   1 
ATOM   645   O  OP2   . C   A 1 31  ? 12.803  34.367  59.239  1.00 68.57  ? 531  C   C OP2   1 
ATOM   646   O  "O5'" . C   A 1 31  ? 12.130  34.219  56.840  1.00 58.52  ? 531  C   C "O5'" 1 
ATOM   647   C  "C5'" . C   A 1 31  ? 11.252  33.897  55.768  1.00 59.07  ? 531  C   C "C5'" 1 
ATOM   648   C  "C4'" . C   A 1 31  ? 11.896  34.233  54.446  1.00 62.55  ? 531  C   C "C4'" 1 
ATOM   649   O  "O4'" . C   A 1 31  ? 12.233  35.651  54.416  1.00 64.68  ? 531  C   C "O4'" 1 
ATOM   650   C  "C3'" . C   A 1 31  ? 13.229  33.557  54.180  1.00 62.24  ? 531  C   C "C3'" 1 
ATOM   651   O  "O3'" . C   A 1 31  ? 13.067  32.226  53.705  1.00 69.43  ? 531  C   C "O3'" 1 
ATOM   652   C  "C2'" . C   A 1 31  ? 13.834  34.466  53.121  1.00 59.01  ? 531  C   C "C2'" 1 
ATOM   653   O  "O2'" . C   A 1 31  ? 13.298  34.250  51.832  1.00 51.55  ? 531  C   C "O2'" 1 
ATOM   654   C  "C1'" . C   A 1 31  ? 13.402  35.841  53.631  1.00 63.44  ? 531  C   C "C1'" 1 
ATOM   655   N  N1    . C   A 1 31  ? 14.440  36.502  54.448  1.00 65.01  ? 531  C   C N1    1 
ATOM   656   C  C2    . C   A 1 31  ? 15.513  37.111  53.788  1.00 65.20  ? 531  C   C C2    1 
ATOM   657   O  O2    . C   A 1 31  ? 15.568  37.053  52.543  1.00 59.90  ? 531  C   C O2    1 
ATOM   658   N  N3    . C   A 1 31  ? 16.465  37.741  54.514  1.00 55.99  ? 531  C   C N3    1 
ATOM   659   C  C4    . C   A 1 31  ? 16.383  37.771  55.842  1.00 49.63  ? 531  C   C C4    1 
ATOM   660   N  N4    . C   A 1 31  ? 17.352  38.405  56.510  1.00 42.70  ? 531  C   C N4    1 
ATOM   661   C  C5    . C   A 1 31  ? 15.309  37.152  56.544  1.00 52.36  ? 531  C   C C5    1 
ATOM   662   C  C6    . C   A 1 31  ? 14.367  36.532  55.814  1.00 61.36  ? 531  C   C C6    1 
ATOM   663   P  P     . C   A 1 32  ? 14.083  31.078  54.199  1.00 73.19  ? 532  C   C P     1 
ATOM   664   O  OP1   . C   A 1 32  ? 13.627  29.788  53.620  1.00 76.20  ? 532  C   C OP1   1 
ATOM   665   O  OP2   . C   A 1 32  ? 14.284  31.195  55.682  1.00 71.71  ? 532  C   C OP2   1 
ATOM   666   O  "O5'" . C   A 1 32  ? 15.450  31.462  53.485  1.00 70.36  ? 532  C   C "O5'" 1 
ATOM   667   C  "C5'" . C   A 1 32  ? 15.543  31.494  52.068  1.00 61.32  ? 532  C   C "C5'" 1 
ATOM   668   C  "C4'" . C   A 1 32  ? 16.879  32.060  51.661  1.00 69.02  ? 532  C   C "C4'" 1 
ATOM   669   O  "O4'" . C   A 1 32  ? 16.964  33.447  52.085  1.00 60.32  ? 532  C   C "O4'" 1 
ATOM   670   C  "C3'" . C   A 1 32  ? 18.080  31.377  52.304  1.00 68.00  ? 532  C   C "C3'" 1 
ATOM   671   O  "O3'" . C   A 1 32  ? 18.474  30.260  51.508  1.00 72.63  ? 532  C   C "O3'" 1 
ATOM   672   C  "C2'" . C   A 1 32  ? 19.132  32.481  52.260  1.00 65.93  ? 532  C   C "C2'" 1 
ATOM   673   O  "O2'" . C   A 1 32  ? 19.720  32.587  50.979  1.00 54.23  ? 532  C   C "O2'" 1 
ATOM   674   C  "C1'" . C   A 1 32  ? 18.281  33.730  52.519  1.00 67.14  ? 532  C   C "C1'" 1 
ATOM   675   N  N1    . C   A 1 32  ? 18.220  34.157  53.931  1.00 69.28  ? 532  C   C N1    1 
ATOM   676   C  C2    . C   A 1 32  ? 19.300  34.881  54.471  1.00 62.12  ? 532  C   C C2    1 
ATOM   677   O  O2    . C   A 1 32  ? 20.296  35.100  53.763  1.00 74.40  ? 532  C   C O2    1 
ATOM   678   N  N3    . C   A 1 32  ? 19.232  35.311  55.747  1.00 52.85  ? 532  C   C N3    1 
ATOM   679   C  C4    . C   A 1 32  ? 18.163  35.031  56.489  1.00 53.28  ? 532  C   C C4    1 
ATOM   680   N  N4    . C   A 1 32  ? 18.147  35.474  57.748  1.00 56.59  ? 532  C   C N4    1 
ATOM   681   C  C5    . C   A 1 32  ? 17.063  34.282  55.977  1.00 60.93  ? 532  C   C C5    1 
ATOM   682   C  C6    . C   A 1 32  ? 17.130  33.869  54.703  1.00 57.05  ? 532  C   C C6    1 
ATOM   683   P  P     . U   A 1 33  ? 18.491  28.780  52.143  1.00 76.62  ? 533  U   C P     1 
ATOM   684   O  OP1   . U   A 1 33  ? 18.788  27.820  51.046  1.00 76.45  ? 533  U   C OP1   1 
ATOM   685   O  OP2   . U   A 1 33  ? 17.266  28.606  52.962  1.00 77.17  ? 533  U   C OP2   1 
ATOM   686   O  "O5'" . U   A 1 33  ? 19.736  28.799  53.137  1.00 73.52  ? 533  U   C "O5'" 1 
ATOM   687   C  "C5'" . U   A 1 33  ? 21.064  28.856  52.633  1.00 70.30  ? 533  U   C "C5'" 1 
ATOM   688   C  "C4'" . U   A 1 33  ? 21.984  29.412  53.683  1.00 68.43  ? 533  U   C "C4'" 1 
ATOM   689   O  "O4'" . U   A 1 33  ? 21.477  30.708  54.093  1.00 66.69  ? 533  U   C "O4'" 1 
ATOM   690   C  "C3'" . U   A 1 33  ? 22.035  28.613  54.972  1.00 69.89  ? 533  U   C "C3'" 1 
ATOM   691   O  "O3'" . U   A 1 33  ? 22.993  27.569  54.877  1.00 69.98  ? 533  U   C "O3'" 1 
ATOM   692   C  "C2'" . U   A 1 33  ? 22.461  29.662  55.988  1.00 69.11  ? 533  U   C "C2'" 1 
ATOM   693   O  "O2'" . U   A 1 33  ? 23.862  29.875  55.987  1.00 73.00  ? 533  U   C "O2'" 1 
ATOM   694   C  "C1'" . U   A 1 33  ? 21.714  30.897  55.476  1.00 66.36  ? 533  U   C "C1'" 1 
ATOM   695   N  N1    . U   A 1 33  ? 20.416  31.086  56.133  1.00 65.50  ? 533  U   C N1    1 
ATOM   696   C  C2    . U   A 1 33  ? 20.368  31.960  57.200  1.00 63.81  ? 533  U   C C2    1 
ATOM   697   O  O2    . U   A 1 33  ? 21.339  32.585  57.575  1.00 46.01  ? 533  U   C O2    1 
ATOM   698   N  N3    . U   A 1 33  ? 19.137  32.075  57.802  1.00 66.83  ? 533  U   C N3    1 
ATOM   699   C  C4    . U   A 1 33  ? 17.971  31.414  57.440  1.00 74.06  ? 533  U   C C4    1 
ATOM   700   O  O4    . U   A 1 33  ? 16.943  31.591  58.099  1.00 82.96  ? 533  U   C O4    1 
ATOM   701   C  C5    . U   A 1 33  ? 18.103  30.539  56.312  1.00 64.20  ? 533  U   C C5    1 
ATOM   702   C  C6    . U   A 1 33  ? 19.290  30.409  55.712  1.00 67.44  ? 533  U   C C6    1 
ATOM   703   P  P     . C   A 1 34  ? 22.890  26.310  55.870  1.00 71.23  ? 534  C   C P     1 
ATOM   704   O  OP1   . C   A 1 34  ? 23.507  25.125  55.196  1.00 63.73  ? 534  C   C OP1   1 
ATOM   705   O  OP2   . C   A 1 34  ? 21.489  26.243  56.384  1.00 61.81  ? 534  C   C OP2   1 
ATOM   706   O  "O5'" . C   A 1 34  ? 23.794  26.716  57.105  1.00 61.88  ? 534  C   C "O5'" 1 
ATOM   707   C  "C5'" . C   A 1 34  ? 23.702  26.025  58.335  1.00 54.23  ? 534  C   C "C5'" 1 
ATOM   708   C  "C4'" . C   A 1 34  ? 24.854  26.431  59.197  1.00 54.21  ? 534  C   C "C4'" 1 
ATOM   709   O  "O4'" . C   A 1 34  ? 26.080  25.884  58.641  1.00 54.15  ? 534  C   C "O4'" 1 
ATOM   710   C  "C3'" . C   A 1 34  ? 25.075  27.934  59.179  1.00 51.17  ? 534  C   C "C3'" 1 
ATOM   711   O  "O3'" . C   A 1 34  ? 24.260  28.559  60.159  1.00 54.02  ? 534  C   C "O3'" 1 
ATOM   712   C  "C2'" . C   A 1 34  ? 26.551  28.043  59.517  1.00 53.31  ? 534  C   C "C2'" 1 
ATOM   713   O  "O2'" . C   A 1 34  ? 26.775  27.876  60.901  1.00 57.31  ? 534  C   C "O2'" 1 
ATOM   714   C  "C1'" . C   A 1 34  ? 27.120  26.843  58.754  1.00 53.61  ? 534  C   C "C1'" 1 
ATOM   715   N  N1    . C   A 1 34  ? 27.586  27.190  57.405  1.00 39.90  ? 534  C   C N1    1 
ATOM   716   C  C2    . C   A 1 34  ? 28.839  27.803  57.265  1.00 46.21  ? 534  C   C C2    1 
ATOM   717   O  O2    . C   A 1 34  ? 29.506  28.035  58.273  1.00 41.85  ? 534  C   C O2    1 
ATOM   718   N  N3    . C   A 1 34  ? 29.288  28.129  56.030  1.00 44.56  ? 534  C   C N3    1 
ATOM   719   C  C4    . C   A 1 34  ? 28.538  27.866  54.961  1.00 45.27  ? 534  C   C C4    1 
ATOM   720   N  N4    . C   A 1 34  ? 29.031  28.188  53.769  1.00 37.10  ? 534  C   C N4    1 
ATOM   721   C  C5    . C   A 1 34  ? 27.252  27.254  55.073  1.00 44.05  ? 534  C   C C5    1 
ATOM   722   C  C6    . C   A 1 34  ? 26.822  26.932  56.305  1.00 45.08  ? 534  C   C C6    1 
ATOM   723   P  P     . U   A 1 35  ? 23.800  30.080  59.953  1.00 54.00  ? 535  U   C P     1 
ATOM   724   O  OP1   . U   A 1 35  ? 22.454  30.254  60.550  1.00 54.24  ? 535  U   C OP1   1 
ATOM   725   O  OP2   . U   A 1 35  ? 24.038  30.444  58.533  1.00 53.35  ? 535  U   C OP2   1 
ATOM   726   O  "O5'" . U   A 1 35  ? 24.808  30.912  60.842  1.00 47.39  ? 535  U   C "O5'" 1 
ATOM   727   C  "C5'" . U   A 1 35  ? 24.852  30.713  62.235  1.00 43.83  ? 535  U   C "C5'" 1 
ATOM   728   C  "C4'" . U   A 1 35  ? 26.038  31.424  62.802  1.00 42.16  ? 535  U   C "C4'" 1 
ATOM   729   O  "O4'" . U   A 1 35  ? 27.210  30.964  62.082  1.00 42.66  ? 535  U   C "O4'" 1 
ATOM   730   C  "C3'" . U   A 1 35  ? 26.049  32.926  62.569  1.00 47.55  ? 535  U   C "C3'" 1 
ATOM   731   O  "O3'" . U   A 1 35  ? 25.281  33.629  63.544  1.00 38.65  ? 535  U   C "O3'" 1 
ATOM   732   C  "C2'" . U   A 1 35  ? 27.533  33.238  62.673  1.00 47.00  ? 535  U   C "C2'" 1 
ATOM   733   O  "O2'" . U   A 1 35  ? 27.970  33.245  64.015  1.00 50.48  ? 535  U   C "O2'" 1 
ATOM   734   C  "C1'" . U   A 1 35  ? 28.136  32.030  61.958  1.00 41.67  ? 535  U   C "C1'" 1 
ATOM   735   N  N1    . U   A 1 35  ? 28.404  32.229  60.528  1.00 41.29  ? 535  U   C N1    1 
ATOM   736   C  C2    . U   A 1 35  ? 29.429  33.101  60.169  1.00 42.22  ? 535  U   C C2    1 
ATOM   737   O  O2    . U   A 1 35  ? 30.061  33.782  60.980  1.00 33.39  ? 535  U   C O2    1 
ATOM   738   N  N3    . U   A 1 35  ? 29.684  33.154  58.823  1.00 41.97  ? 535  U   C N3    1 
ATOM   739   C  C4    . U   A 1 35  ? 29.038  32.465  57.822  1.00 48.91  ? 535  U   C C4    1 
ATOM   740   O  O4    . U   A 1 35  ? 29.494  32.511  56.679  1.00 51.67  ? 535  U   C O4    1 
ATOM   741   C  C5    . U   A 1 35  ? 27.959  31.628  58.268  1.00 46.57  ? 535  U   C C5    1 
ATOM   742   C  C6    . U   A 1 35  ? 27.688  31.543  59.576  1.00 37.62  ? 535  U   C C6    1 
ATOM   743   P  P     . C   A 1 36  ? 24.318  34.817  63.071  1.00 50.80  ? 536  C   C P     1 
ATOM   744   O  OP1   . C   A 1 36  ? 23.548  35.312  64.236  1.00 60.86  ? 536  C   C OP1   1 
ATOM   745   O  OP2   . C   A 1 36  ? 23.593  34.383  61.842  1.00 46.03  ? 536  C   C OP2   1 
ATOM   746   O  "O5'" . C   A 1 36  ? 25.338  35.961  62.650  1.00 50.17  ? 536  C   C "O5'" 1 
ATOM   747   C  "C5'" . C   A 1 36  ? 26.200  36.539  63.615  1.00 48.86  ? 536  C   C "C5'" 1 
ATOM   748   C  "C4'" . C   A 1 36  ? 27.225  37.404  62.938  1.00 49.77  ? 536  C   C "C4'" 1 
ATOM   749   O  "O4'" . C   A 1 36  ? 28.058  36.572  62.087  1.00 53.97  ? 536  C   C "O4'" 1 
ATOM   750   C  "C3'" . C   A 1 36  ? 26.671  38.450  61.984  1.00 48.81  ? 536  C   C "C3'" 1 
ATOM   751   O  "O3'" . C   A 1 36  ? 26.226  39.615  62.679  1.00 41.02  ? 536  C   C "O3'" 1 
ATOM   752   C  "C2'" . C   A 1 36  ? 27.884  38.727  61.106  1.00 47.56  ? 536  C   C "C2'" 1 
ATOM   753   O  "O2'" . C   A 1 36  ? 28.833  39.555  61.748  1.00 46.60  ? 536  C   C "O2'" 1 
ATOM   754   C  "C1'" . C   A 1 36  ? 28.465  37.317  60.950  1.00 52.11  ? 536  C   C "C1'" 1 
ATOM   755   N  N1    . C   A 1 36  ? 27.992  36.617  59.744  1.00 47.92  ? 536  C   C N1    1 
ATOM   756   C  C2    . C   A 1 36  ? 28.690  36.796  58.546  1.00 40.40  ? 536  C   C C2    1 
ATOM   757   O  O2    . C   A 1 36  ? 29.687  37.540  58.532  1.00 48.96  ? 536  C   C O2    1 
ATOM   758   N  N3    . C   A 1 36  ? 28.269  36.160  57.436  1.00 40.06  ? 536  C   C N3    1 
ATOM   759   C  C4    . C   A 1 36  ? 27.196  35.372  57.483  1.00 46.28  ? 536  C   C C4    1 
ATOM   760   N  N4    . C   A 1 36  ? 26.821  34.767  56.348  1.00 44.68  ? 536  C   C N4    1 
ATOM   761   C  C5    . C   A 1 36  ? 26.460  35.169  58.690  1.00 38.81  ? 536  C   C C5    1 
ATOM   762   C  C6    . C   A 1 36  ? 26.890  35.806  59.787  1.00 45.29  ? 536  C   C C6    1 
ATOM   763   P  P     . A   A 1 37  ? 25.211  40.627  61.957  1.00 50.22  ? 537  A   C P     1 
ATOM   764   O  OP1   . A   A 1 37  ? 24.816  41.663  62.955  1.00 48.82  ? 537  A   C OP1   1 
ATOM   765   O  OP2   . A   A 1 37  ? 24.154  39.884  61.208  1.00 35.51  ? 537  A   C OP2   1 
ATOM   766   O  "O5'" . A   A 1 37  ? 26.136  41.313  60.863  1.00 46.05  ? 537  A   C "O5'" 1 
ATOM   767   C  "C5'" . A   A 1 37  ? 25.635  41.622  59.580  1.00 40.24  ? 537  A   C "C5'" 1 
ATOM   768   C  "C4'" . A   A 1 37  ? 26.780  41.724  58.608  1.00 45.39  ? 537  A   C "C4'" 1 
ATOM   769   O  "O4'" . A   A 1 37  ? 27.374  40.415  58.432  1.00 32.69  ? 537  A   C "O4'" 1 
ATOM   770   C  "C3'" . A   A 1 37  ? 26.396  42.152  57.206  1.00 47.17  ? 537  A   C "C3'" 1 
ATOM   771   O  "O3'" . A   A 1 37  ? 26.337  43.575  57.156  1.00 51.89  ? 537  A   C "O3'" 1 
ATOM   772   C  "C2'" . A   A 1 37  ? 27.563  41.611  56.402  1.00 45.13  ? 537  A   C "C2'" 1 
ATOM   773   O  "O2'" . A   A 1 37  ? 28.713  42.418  56.558  1.00 51.42  ? 537  A   C "O2'" 1 
ATOM   774   C  "C1'" . A   A 1 37  ? 27.788  40.261  57.088  1.00 36.86  ? 537  A   C "C1'" 1 
ATOM   775   N  N9    . A   A 1 37  ? 26.974  39.218  56.478  1.00 40.08  ? 537  A   C N9    1 
ATOM   776   C  C8    . A   A 1 37  ? 25.896  38.550  57.007  1.00 34.70  ? 537  A   C C8    1 
ATOM   777   N  N7    . A   A 1 37  ? 25.335  37.706  56.168  1.00 45.13  ? 537  A   C N7    1 
ATOM   778   C  C5    . A   A 1 37  ? 26.110  37.816  55.017  1.00 45.01  ? 537  A   C C5    1 
ATOM   779   C  C6    . A   A 1 37  ? 26.037  37.196  53.749  1.00 42.57  ? 537  A   C C6    1 
ATOM   780   N  N6    . A   A 1 37  ? 25.092  36.328  53.388  1.00 37.72  ? 537  A   C N6    1 
ATOM   781   N  N1    . A   A 1 37  ? 26.980  37.517  52.844  1.00 38.04  ? 537  A   C N1    1 
ATOM   782   C  C2    . A   A 1 37  ? 27.904  38.415  53.177  1.00 42.44  ? 537  A   C C2    1 
ATOM   783   N  N3    . A   A 1 37  ? 28.063  39.081  54.316  1.00 44.98  ? 537  A   C N3    1 
ATOM   784   C  C4    . A   A 1 37  ? 27.130  38.730  55.204  1.00 36.77  ? 537  A   C C4    1 
ATOM   785   P  P     . A   A 1 38  ? 25.150  44.295  56.352  1.00 53.53  ? 538  A   C P     1 
ATOM   786   O  OP1   . A   A 1 38  ? 25.359  45.770  56.503  1.00 59.84  ? 538  A   C OP1   1 
ATOM   787   O  OP2   . A   A 1 38  ? 23.881  43.677  56.801  1.00 48.04  ? 538  A   C OP2   1 
ATOM   788   O  "O5'" . A   A 1 38  ? 25.402  43.879  54.831  1.00 40.31  ? 538  A   C "O5'" 1 
ATOM   789   C  "C5'" . A   A 1 38  ? 26.636  44.186  54.189  1.00 26.02  ? 538  A   C "C5'" 1 
ATOM   790   C  "C4'" . A   A 1 38  ? 26.705  43.515  52.837  1.00 37.51  ? 538  A   C "C4'" 1 
ATOM   791   O  "O4'" . A   A 1 38  ? 26.911  42.095  53.005  1.00 39.51  ? 538  A   C "O4'" 1 
ATOM   792   C  "C3'" . A   A 1 38  ? 25.445  43.618  51.996  1.00 44.00  ? 538  A   C "C3'" 1 
ATOM   793   O  "O3'" . A   A 1 38  ? 25.424  44.819  51.251  1.00 47.91  ? 538  A   C "O3'" 1 
ATOM   794   C  "C2'" . A   A 1 38  ? 25.565  42.408  51.085  1.00 42.45  ? 538  A   C "C2'" 1 
ATOM   795   O  "O2'" . A   A 1 38  ? 26.487  42.600  50.037  1.00 47.56  ? 538  A   C "O2'" 1 
ATOM   796   C  "C1'" . A   A 1 38  ? 26.126  41.380  52.059  1.00 47.44  ? 538  A   C "C1'" 1 
ATOM   797   N  N9    . A   A 1 38  ? 25.061  40.702  52.788  1.00 42.05  ? 538  A   C N9    1 
ATOM   798   C  C8    . A   A 1 38  ? 24.678  40.929  54.086  1.00 46.69  ? 538  A   C C8    1 
ATOM   799   N  N7    . A   A 1 38  ? 23.706  40.152  54.492  1.00 40.66  ? 538  A   C N7    1 
ATOM   800   C  C5    . A   A 1 38  ? 23.424  39.367  53.385  1.00 39.60  ? 538  A   C C5    1 
ATOM   801   C  C6    . A   A 1 38  ? 22.491  38.350  53.174  1.00 40.79  ? 538  A   C C6    1 
ATOM   802   N  N6    . A   A 1 38  ? 21.630  37.933  54.109  1.00 37.13  ? 538  A   C N6    1 
ATOM   803   N  N1    . A   A 1 38  ? 22.462  37.769  51.955  1.00 50.90  ? 538  A   C N1    1 
ATOM   804   C  C2    . A   A 1 38  ? 23.323  38.198  51.018  1.00 39.02  ? 538  A   C C2    1 
ATOM   805   N  N3    . A   A 1 38  ? 24.245  39.155  51.101  1.00 49.28  ? 538  A   C N3    1 
ATOM   806   C  C4    . A   A 1 38  ? 24.244  39.704  52.325  1.00 42.24  ? 538  A   C C4    1 
ATOM   807   P  P     . G   A 1 39  ? 24.020  45.541  50.947  1.00 44.31  ? 539  G   C P     1 
ATOM   808   O  OP1   . G   A 1 39  ? 24.325  46.648  50.004  1.00 43.93  ? 539  G   C OP1   1 
ATOM   809   O  OP2   . G   A 1 39  ? 23.348  45.828  52.249  1.00 38.59  ? 539  G   C OP2   1 
ATOM   810   O  "O5'" . G   A 1 39  ? 23.144  44.460  50.175  1.00 37.77  ? 539  G   C "O5'" 1 
ATOM   811   C  "C5'" . G   A 1 39  ? 23.438  44.096  48.839  1.00 37.53  ? 539  G   C "C5'" 1 
ATOM   812   C  "C4'" . G   A 1 39  ? 22.502  43.002  48.378  1.00 46.19  ? 539  G   C "C4'" 1 
ATOM   813   O  "O4'" . G   A 1 39  ? 22.680  41.823  49.205  1.00 44.05  ? 539  G   C "O4'" 1 
ATOM   814   C  "C3'" . G   A 1 39  ? 21.014  43.280  48.505  1.00 40.28  ? 539  G   C "C3'" 1 
ATOM   815   O  "O3'" . G   A 1 39  ? 20.546  44.051  47.418  1.00 50.50  ? 539  G   C "O3'" 1 
ATOM   816   C  "C2'" . G   A 1 39  ? 20.448  41.880  48.432  1.00 45.14  ? 539  G   C "C2'" 1 
ATOM   817   O  "O2'" . G   A 1 39  ? 20.494  41.391  47.102  1.00 45.23  ? 539  G   C "O2'" 1 
ATOM   818   C  "C1'" . G   A 1 39  ? 21.447  41.127  49.311  1.00 45.55  ? 539  G   C "C1'" 1 
ATOM   819   N  N9    . G   A 1 39  ? 21.056  41.115  50.718  1.00 39.28  ? 539  G   C N9    1 
ATOM   820   C  C8    . G   A 1 39  ? 21.573  41.892  51.716  1.00 33.20  ? 539  G   C C8    1 
ATOM   821   N  N7    . G   A 1 39  ? 21.019  41.674  52.876  1.00 32.70  ? 539  G   C N7    1 
ATOM   822   C  C5    . G   A 1 39  ? 20.078  40.689  52.627  1.00 40.81  ? 539  G   C C5    1 
ATOM   823   C  C6    . G   A 1 39  ? 19.173  40.034  53.510  1.00 46.80  ? 539  G   C C6    1 
ATOM   824   O  O6    . G   A 1 39  ? 19.015  40.204  54.728  1.00 41.90  ? 539  G   C O6    1 
ATOM   825   N  N1    . G   A 1 39  ? 18.409  39.088  52.844  1.00 41.12  ? 539  G   C N1    1 
ATOM   826   C  C2    . G   A 1 39  ? 18.501  38.800  51.514  1.00 44.33  ? 539  G   C C2    1 
ATOM   827   N  N2    . G   A 1 39  ? 17.662  37.852  51.066  1.00 53.63  ? 539  G   C N2    1 
ATOM   828   N  N3    . G   A 1 39  ? 19.345  39.393  50.681  1.00 46.18  ? 539  G   C N3    1 
ATOM   829   C  C4    . G   A 1 39  ? 20.093  40.324  51.303  1.00 41.74  ? 539  G   C C4    1 
ATOM   830   P  P     . G   A 1 40  ? 19.257  44.989  47.613  1.00 58.80  ? 540  G   C P     1 
ATOM   831   O  OP1   . G   A 1 40  ? 19.130  45.824  46.396  1.00 51.19  ? 540  G   C OP1   1 
ATOM   832   O  OP2   . G   A 1 40  ? 19.352  45.638  48.955  1.00 49.22  ? 540  G   C OP2   1 
ATOM   833   O  "O5'" . G   A 1 40  ? 18.044  43.961  47.660  1.00 57.00  ? 540  G   C "O5'" 1 
ATOM   834   C  "C5'" . G   A 1 40  ? 17.703  43.166  46.531  1.00 51.03  ? 540  G   C "C5'" 1 
ATOM   835   C  "C4'" . G   A 1 40  ? 16.553  42.255  46.880  1.00 56.79  ? 540  G   C "C4'" 1 
ATOM   836   O  "O4'" . G   A 1 40  ? 16.985  41.318  47.902  1.00 53.32  ? 540  G   C "O4'" 1 
ATOM   837   C  "C3'" . G   A 1 40  ? 15.350  42.942  47.514  1.00 65.06  ? 540  G   C "C3'" 1 
ATOM   838   O  "O3'" . G   A 1 40  ? 14.494  43.530  46.540  1.00 72.62  ? 540  G   C "O3'" 1 
ATOM   839   C  "C2'" . G   A 1 40  ? 14.683  41.793  48.254  1.00 64.96  ? 540  G   C "C2'" 1 
ATOM   840   O  "O2'" . G   A 1 40  ? 13.935  40.939  47.407  1.00 78.02  ? 540  G   C "O2'" 1 
ATOM   841   C  "C1'" . G   A 1 40  ? 15.906  41.040  48.779  1.00 57.22  ? 540  G   C "C1'" 1 
ATOM   842   N  N9    . G   A 1 40  ? 16.274  41.481  50.117  1.00 54.99  ? 540  G   C N9    1 
ATOM   843   C  C8    . G   A 1 40  ? 17.289  42.340  50.471  1.00 48.22  ? 540  G   C C8    1 
ATOM   844   N  N7    . G   A 1 40  ? 17.379  42.518  51.761  1.00 52.72  ? 540  G   C N7    1 
ATOM   845   C  C5    . G   A 1 40  ? 16.359  41.733  52.288  1.00 51.09  ? 540  G   C C5    1 
ATOM   846   C  C6    . G   A 1 40  ? 15.963  41.512  53.632  1.00 45.15  ? 540  G   C C6    1 
ATOM   847   O  O6    . G   A 1 40  ? 16.453  41.974  54.666  1.00 46.45  ? 540  G   C O6    1 
ATOM   848   N  N1    . G   A 1 40  ? 14.871  40.656  53.710  1.00 51.20  ? 540  G   C N1    1 
ATOM   849   C  C2    . G   A 1 40  ? 14.236  40.085  52.636  1.00 58.44  ? 540  G   C C2    1 
ATOM   850   N  N2    . G   A 1 40  ? 13.190  39.294  52.914  1.00 60.83  ? 540  G   C N2    1 
ATOM   851   N  N3    . G   A 1 40  ? 14.597  40.276  51.381  1.00 54.53  ? 540  G   C N3    1 
ATOM   852   C  C4    . G   A 1 40  ? 15.660  41.101  51.282  1.00 53.53  ? 540  G   C C4    1 
ATOM   853   P  P     . C   A 1 41  ? 13.676  44.864  46.907  1.00 76.89  ? 541  C   C P     1 
ATOM   854   O  OP1   . C   A 1 41  ? 13.032  45.359  45.663  1.00 83.51  ? 541  C   C OP1   1 
ATOM   855   O  OP2   . C   A 1 41  ? 14.565  45.772  47.679  1.00 72.49  ? 541  C   C OP2   1 
ATOM   856   O  "O5'" . C   A 1 41  ? 12.536  44.316  47.871  1.00 76.65  ? 541  C   C "O5'" 1 
ATOM   857   C  "C5'" . C   A 1 41  ? 11.615  43.346  47.393  1.00 71.05  ? 541  C   C "C5'" 1 
ATOM   858   C  "C4'" . C   A 1 41  ? 10.772  42.817  48.522  1.00 69.85  ? 541  C   C "C4'" 1 
ATOM   859   O  "O4'" . C   A 1 41  ? 11.619  42.113  49.468  1.00 58.93  ? 541  C   C "O4'" 1 
ATOM   860   C  "C3'" . C   A 1 41  ? 10.055  43.848  49.381  1.00 66.84  ? 541  C   C "C3'" 1 
ATOM   861   O  "O3'" . C   A 1 41  ? 8.848   44.311  48.784  1.00 72.95  ? 541  C   C "O3'" 1 
ATOM   862   C  "C2'" . C   A 1 41  ? 9.765   43.039  50.633  1.00 63.30  ? 541  C   C "C2'" 1 
ATOM   863   O  "O2'" . C   A 1 41  ? 8.645   42.200  50.446  1.00 63.05  ? 541  C   C "O2'" 1 
ATOM   864   C  "C1'" . C   A 1 41  ? 11.052  42.213  50.761  1.00 56.35  ? 541  C   C "C1'" 1 
ATOM   865   N  N1    . C   A 1 41  ? 12.033  42.866  51.630  1.00 57.14  ? 541  C   C N1    1 
ATOM   866   C  C2    . C   A 1 41  ? 11.871  42.754  53.007  1.00 56.62  ? 541  C   C C2    1 
ATOM   867   O  O2    . C   A 1 41  ? 10.905  42.107  53.437  1.00 56.83  ? 541  C   C O2    1 
ATOM   868   N  N3    . C   A 1 41  ? 12.764  43.348  53.832  1.00 52.66  ? 541  C   C N3    1 
ATOM   869   C  C4    . C   A 1 41  ? 13.785  44.038  53.319  1.00 57.84  ? 541  C   C C4    1 
ATOM   870   N  N4    . C   A 1 41  ? 14.644  44.615  54.170  1.00 52.86  ? 541  C   C N4    1 
ATOM   871   C  C5    . C   A 1 41  ? 13.973  44.171  51.908  1.00 54.22  ? 541  C   C C5    1 
ATOM   872   C  C6    . C   A 1 41  ? 13.081  43.571  51.108  1.00 51.77  ? 541  C   C C6    1 
ATOM   873   P  P     . C   A 1 42  ? 8.319   45.796  49.107  1.00 77.25  ? 542  C   C P     1 
ATOM   874   O  OP1   . C   A 1 42  ? 7.144   46.074  48.242  1.00 86.27  ? 542  C   C OP1   1 
ATOM   875   O  OP2   . C   A 1 42  ? 9.490   46.709  49.058  1.00 85.70  ? 542  C   C OP2   1 
ATOM   876   O  "O5'" . C   A 1 42  ? 7.828   45.713  50.624  1.00 78.75  ? 542  C   C "O5'" 1 
ATOM   877   C  "C5'" . C   A 1 42  ? 6.681   44.943  50.970  1.00 77.17  ? 542  C   C "C5'" 1 
ATOM   878   C  "C4'" . C   A 1 42  ? 6.519   44.848  52.472  1.00 69.86  ? 542  C   C "C4'" 1 
ATOM   879   O  "O4'" . C   A 1 42  ? 7.679   44.191  53.057  1.00 69.42  ? 542  C   C "O4'" 1 
ATOM   880   C  "C3'" . C   A 1 42  ? 6.404   46.148  53.250  1.00 70.98  ? 542  C   C "C3'" 1 
ATOM   881   O  "O3'" . C   A 1 42  ? 5.078   46.688  53.173  1.00 74.42  ? 542  C   C "O3'" 1 
ATOM   882   C  "C2'" . C   A 1 42  ? 6.758   45.681  54.664  1.00 73.45  ? 542  C   C "C2'" 1 
ATOM   883   O  "O2'" . C   A 1 42  ? 5.691   45.035  55.327  1.00 75.47  ? 542  C   C "O2'" 1 
ATOM   884   C  "C1'" . C   A 1 42  ? 7.870   44.664  54.386  1.00 67.87  ? 542  C   C "C1'" 1 
ATOM   885   N  N1    . C   A 1 42  ? 9.202   45.290  54.485  1.00 65.83  ? 542  C   C N1    1 
ATOM   886   C  C2    . C   A 1 42  ? 9.734   45.547  55.764  1.00 58.33  ? 542  C   C C2    1 
ATOM   887   O  O2    . C   A 1 42  ? 9.087   45.216  56.763  1.00 50.41  ? 542  C   C O2    1 
ATOM   888   N  N3    . C   A 1 42  ? 10.933  46.161  55.866  1.00 61.58  ? 542  C   C N3    1 
ATOM   889   C  C4    . C   A 1 42  ? 11.594  46.523  54.762  1.00 56.02  ? 542  C   C C4    1 
ATOM   890   N  N4    . C   A 1 42  ? 12.758  47.151  54.917  1.00 54.27  ? 542  C   C N4    1 
ATOM   891   C  C5    . C   A 1 42  ? 11.086  46.260  53.451  1.00 53.82  ? 542  C   C C5    1 
ATOM   892   C  C6    . C   A 1 42  ? 9.903   45.643  53.360  1.00 57.28  ? 542  C   C C6    1 
ATOM   893   P  P     . G   A 1 43  ? 4.840   48.284  53.315  1.00 68.75  ? 543  G   C P     1 
ATOM   894   O  OP1   . G   A 1 43  ? 3.400   48.555  53.104  1.00 73.03  ? 543  G   C OP1   1 
ATOM   895   O  OP2   . G   A 1 43  ? 5.836   48.981  52.469  1.00 64.29  ? 543  G   C OP2   1 
ATOM   896   O  "O5'" . G   A 1 43  ? 5.170   48.587  54.846  1.00 64.91  ? 543  G   C "O5'" 1 
ATOM   897   C  "C5'" . G   A 1 43  ? 4.488   47.893  55.878  1.00 55.28  ? 543  G   C "C5'" 1 
ATOM   898   C  "C4'" . G   A 1 43  ? 5.144   48.144  57.212  1.00 54.74  ? 543  G   C "C4'" 1 
ATOM   899   O  "O4'" . G   A 1 43  ? 6.509   47.653  57.193  1.00 57.50  ? 543  G   C "O4'" 1 
ATOM   900   C  "C3'" . G   A 1 43  ? 5.301   49.597  57.611  1.00 58.04  ? 543  G   C "C3'" 1 
ATOM   901   O  "O3'" . G   A 1 43  ? 4.081   50.128  58.115  1.00 53.68  ? 543  G   C "O3'" 1 
ATOM   902   C  "C2'" . G   A 1 43  ? 6.402   49.520  58.671  1.00 65.60  ? 543  G   C "C2'" 1 
ATOM   903   O  "O2'" . G   A 1 43  ? 5.963   49.126  59.960  1.00 61.70  ? 543  G   C "O2'" 1 
ATOM   904   C  "C1'" . G   A 1 43  ? 7.294   48.411  58.103  1.00 63.08  ? 543  G   C "C1'" 1 
ATOM   905   N  N9    . G   A 1 43  ? 8.497   48.901  57.424  1.00 58.03  ? 543  G   C N9    1 
ATOM   906   C  C8    . G   A 1 43  ? 8.758   48.914  56.074  1.00 50.66  ? 543  G   C C8    1 
ATOM   907   N  N7    . G   A 1 43  ? 9.944   49.381  55.788  1.00 42.63  ? 543  G   C N7    1 
ATOM   908   C  C5    . G   A 1 43  ? 10.492  49.702  57.019  1.00 42.10  ? 543  G   C C5    1 
ATOM   909   C  C6    . G   A 1 43  ? 11.762  50.245  57.346  1.00 51.41  ? 543  G   C C6    1 
ATOM   910   O  O6    . G   A 1 43  ? 12.696  50.537  56.583  1.00 52.12  ? 543  G   C O6    1 
ATOM   911   N  N1    . G   A 1 43  ? 11.900  50.432  58.720  1.00 44.86  ? 543  G   C N1    1 
ATOM   912   C  C2    . G   A 1 43  ? 10.949  50.125  59.655  1.00 44.86  ? 543  G   C C2    1 
ATOM   913   N  N2    . G   A 1 43  ? 11.272  50.374  60.928  1.00 43.64  ? 543  G   C N2    1 
ATOM   914   N  N3    . G   A 1 43  ? 9.767   49.611  59.363  1.00 48.40  ? 543  G   C N3    1 
ATOM   915   C  C4    . G   A 1 43  ? 9.609   49.427  58.036  1.00 42.04  ? 543  G   C C4    1 
ATOM   916   P  P     . A   A 1 44  ? 3.780   51.704  57.978  1.00 56.25  ? 544  A   C P     1 
ATOM   917   O  OP1   . A   A 1 44  ? 2.314   51.959  58.059  1.00 55.55  ? 544  A   C OP1   1 
ATOM   918   O  OP2   . A   A 1 44  ? 4.529   52.188  56.791  1.00 54.46  ? 544  A   C OP2   1 
ATOM   919   O  "O5'" . A   A 1 44  ? 4.480   52.321  59.263  1.00 47.89  ? 544  A   C "O5'" 1 
ATOM   920   C  "C5'" . A   A 1 44  ? 4.121   51.905  60.564  1.00 42.09  ? 544  A   C "C5'" 1 
ATOM   921   C  "C4'" . A   A 1 44  ? 5.107   52.454  61.562  1.00 48.98  ? 544  A   C "C4'" 1 
ATOM   922   O  "O4'" . A   A 1 44  ? 6.394   51.810  61.368  1.00 54.88  ? 544  A   C "O4'" 1 
ATOM   923   C  "C3'" . A   A 1 44  ? 5.428   53.934  61.418  1.00 54.40  ? 544  A   C "C3'" 1 
ATOM   924   O  "O3'" . A   A 1 44  ? 4.453   54.768  62.029  1.00 56.73  ? 544  A   C "O3'" 1 
ATOM   925   C  "C2'" . A   A 1 44  ? 6.775   54.033  62.121  1.00 57.50  ? 544  A   C "C2'" 1 
ATOM   926   O  "O2'" . A   A 1 44  ? 6.687   54.075  63.533  1.00 60.13  ? 544  A   C "O2'" 1 
ATOM   927   C  "C1'" . A   A 1 44  ? 7.436   52.730  61.671  1.00 55.66  ? 544  A   C "C1'" 1 
ATOM   928   N  N9    . A   A 1 44  ? 8.235   52.937  60.470  1.00 47.47  ? 544  A   C N9    1 
ATOM   929   C  C8    . A   A 1 44  ? 7.864   52.800  59.156  1.00 52.00  ? 544  A   C C8    1 
ATOM   930   N  N7    . A   A 1 44  ? 8.824   53.057  58.306  1.00 47.33  ? 544  A   C N7    1 
ATOM   931   C  C5    . A   A 1 44  ? 9.902   53.392  59.118  1.00 54.14  ? 544  A   C C5    1 
ATOM   932   C  C6    . A   A 1 44  ? 11.236  53.758  58.830  1.00 47.28  ? 544  A   C C6    1 
ATOM   933   N  N6    . A   A 1 44  ? 11.713  53.893  57.597  1.00 39.50  ? 544  A   C N6    1 
ATOM   934   N  N1    . A   A 1 44  ? 12.064  53.989  59.874  1.00 52.25  ? 544  A   C N1    1 
ATOM   935   C  C2    . A   A 1 44  ? 11.573  53.880  61.118  1.00 50.81  ? 544  A   C C2    1 
ATOM   936   N  N3    . A   A 1 44  ? 10.336  53.560  61.513  1.00 55.38  ? 544  A   C N3    1 
ATOM   937   C  C4    . A   A 1 44  ? 9.546   53.321  60.452  1.00 49.13  ? 544  A   C C4    1 
ATOM   938   P  P     . A   A 1 45  ? 3.957   56.089  61.269  1.00 55.58  ? 545  A   C P     1 
ATOM   939   O  OP1   . A   A 1 45  ? 2.981   56.793  62.141  1.00 62.33  ? 545  A   C OP1   1 
ATOM   940   O  OP2   . A   A 1 45  ? 3.577   55.697  59.884  1.00 45.88  ? 545  A   C OP2   1 
ATOM   941   O  "O5'" . A   A 1 45  ? 5.251   57.005  61.225  1.00 52.29  ? 545  A   C "O5'" 1 
ATOM   942   C  "C5'" . A   A 1 45  ? 5.870   57.421  62.427  1.00 38.89  ? 545  A   C "C5'" 1 
ATOM   943   C  "C4'" . A   A 1 45  ? 7.179   58.105  62.120  1.00 55.14  ? 545  A   C "C4'" 1 
ATOM   944   O  "O4'" . A   A 1 45  ? 8.141   57.143  61.594  1.00 56.11  ? 545  A   C "O4'" 1 
ATOM   945   C  "C3'" . A   A 1 45  ? 7.151   59.162  61.029  1.00 50.95  ? 545  A   C "C3'" 1 
ATOM   946   O  "O3'" . A   A 1 45  ? 6.642   60.393  61.514  1.00 53.03  ? 545  A   C "O3'" 1 
ATOM   947   C  "C2'" . A   A 1 45  ? 8.635   59.285  60.725  1.00 46.44  ? 545  A   C "C2'" 1 
ATOM   948   O  "O2'" . A   A 1 45  ? 9.304   59.981  61.757  1.00 39.30  ? 545  A   C "O2'" 1 
ATOM   949   C  "C1'" . A   A 1 45  ? 9.062   57.815  60.746  1.00 48.27  ? 545  A   C "C1'" 1 
ATOM   950   N  N9    . A   A 1 45  ? 9.012   57.230  59.402  1.00 43.70  ? 545  A   C N9    1 
ATOM   951   C  C8    . A   A 1 45  ? 7.944   56.699  58.734  1.00 41.72  ? 545  A   C C8    1 
ATOM   952   N  N7    . A   A 1 45  ? 8.204   56.379  57.486  1.00 41.02  ? 545  A   C N7    1 
ATOM   953   C  C5    . A   A 1 45  ? 9.544   56.694  57.333  1.00 34.43  ? 545  A   C C5    1 
ATOM   954   C  C6    . A   A 1 45  ? 10.420  56.619  56.228  1.00 44.58  ? 545  A   C C6    1 
ATOM   955   N  N6    . A   A 1 45  ? 10.048  56.214  55.004  1.00 31.87  ? 545  A   C N6    1 
ATOM   956   N  N1    . A   A 1 45  ? 11.710  56.997  56.423  1.00 37.51  ? 545  A   C N1    1 
ATOM   957   C  C2    . A   A 1 45  ? 12.076  57.431  57.637  1.00 36.49  ? 545  A   C C2    1 
ATOM   958   N  N3    . A   A 1 45  ? 11.342  57.565  58.741  1.00 39.95  ? 545  A   C N3    1 
ATOM   959   C  C4    . A   A 1 45  ? 10.068  57.180  58.517  1.00 47.40  ? 545  A   C C4    1 
ATOM   960   P  P     . A   A 1 46  ? 5.427   61.106  60.750  1.00 50.82  ? 546  A   C P     1 
ATOM   961   O  OP1   . A   A 1 46  ? 4.452   61.413  61.834  1.00 53.14  ? 546  A   C OP1   1 
ATOM   962   O  OP2   . A   A 1 46  ? 5.013   60.283  59.579  1.00 48.84  ? 546  A   C OP2   1 
ATOM   963   O  "O5'" . A   A 1 46  ? 6.040   62.462  60.179  1.00 42.95  ? 546  A   C "O5'" 1 
ATOM   964   C  "C5'" . A   A 1 46  ? 6.662   63.396  61.053  1.00 48.12  ? 546  A   C "C5'" 1 
ATOM   965   C  "C4'" . A   A 1 46  ? 7.290   64.523  60.267  1.00 55.90  ? 546  A   C "C4'" 1 
ATOM   966   O  "O4'" . A   A 1 46  ? 8.220   63.973  59.292  1.00 54.76  ? 546  A   C "O4'" 1 
ATOM   967   C  "C3'" . A   A 1 46  ? 6.352   65.384  59.441  1.00 55.92  ? 546  A   C "C3'" 1 
ATOM   968   O  "O3'" . A   A 1 46  ? 5.814   66.416  60.264  1.00 60.01  ? 546  A   C "O3'" 1 
ATOM   969   C  "C2'" . A   A 1 46  ? 7.313   65.969  58.416  1.00 55.18  ? 546  A   C "C2'" 1 
ATOM   970   O  "O2'" . A   A 1 46  ? 8.114   66.970  59.026  1.00 52.95  ? 546  A   C "O2'" 1 
ATOM   971   C  "C1'" . A   A 1 46  ? 8.212   64.765  58.125  1.00 49.14  ? 546  A   C "C1'" 1 
ATOM   972   N  N9    . A   A 1 46  ? 7.816   63.917  56.994  1.00 50.11  ? 546  A   C N9    1 
ATOM   973   C  C8    . A   A 1 46  ? 6.712   63.109  56.864  1.00 47.28  ? 546  A   C C8    1 
ATOM   974   N  N7    . A   A 1 46  ? 6.655   62.469  55.717  1.00 44.25  ? 546  A   C N7    1 
ATOM   975   C  C5    . A   A 1 46  ? 7.800   62.879  55.047  1.00 46.20  ? 546  A   C C5    1 
ATOM   976   C  C6    . A   A 1 46  ? 8.332   62.558  53.778  1.00 38.00  ? 546  A   C C6    1 
ATOM   977   N  N6    . A   A 1 46  ? 7.778   61.691  52.923  1.00 32.11  ? 546  A   C N6    1 
ATOM   978   N  N1    . A   A 1 46  ? 9.477   63.165  53.414  1.00 37.96  ? 546  A   C N1    1 
ATOM   979   C  C2    . A   A 1 46  ? 10.061  64.007  54.271  1.00 44.82  ? 546  A   C C2    1 
ATOM   980   N  N3    . A   A 1 46  ? 9.678   64.373  55.488  1.00 42.46  ? 546  A   C N3    1 
ATOM   981   C  C4    . A   A 1 46  ? 8.522   63.773  55.820  1.00 45.82  ? 546  A   C C4    1 
ATOM   982   P  P     . C   A 1 47  ? 4.234   66.715  60.239  1.00 51.12  ? 548  C   C P     1 
ATOM   983   O  OP1   . C   A 1 47  ? 3.990   67.628  61.381  1.00 54.77  ? 548  C   C OP1   1 
ATOM   984   O  OP2   . C   A 1 47  ? 3.525   65.411  60.160  1.00 56.56  ? 548  C   C OP2   1 
ATOM   985   O  "O5'" . C   A 1 47  ? 3.974   67.436  58.839  1.00 54.43  ? 548  C   C "O5'" 1 
ATOM   986   C  "C5'" . C   A 1 47  ? 4.238   68.824  58.645  1.00 55.59  ? 548  C   C "C5'" 1 
ATOM   987   C  "C4'" . C   A 1 47  ? 5.546   69.003  57.909  1.00 54.99  ? 548  C   C "C4'" 1 
ATOM   988   O  "O4'" . C   A 1 47  ? 5.486   68.287  56.649  1.00 54.96  ? 548  C   C "O4'" 1 
ATOM   989   C  "C3'" . C   A 1 47  ? 5.785   70.467  57.543  1.00 54.96  ? 548  C   C "C3'" 1 
ATOM   990   O  "O3'" . C   A 1 47  ? 7.088   70.912  57.912  1.00 61.73  ? 548  C   C "O3'" 1 
ATOM   991   C  "C2'" . C   A 1 47  ? 5.356   70.621  56.083  1.00 46.82  ? 548  C   C "C2'" 1 
ATOM   992   O  "O2'" . C   A 1 47  ? 6.242   71.396  55.322  1.00 57.70  ? 548  C   C "O2'" 1 
ATOM   993   C  "C1'" . C   A 1 47  ? 5.530   69.198  55.573  1.00 49.70  ? 548  C   C "C1'" 1 
ATOM   994   N  N1    . C   A 1 47  ? 4.716   68.700  54.464  1.00 47.27  ? 548  C   C N1    1 
ATOM   995   C  C2    . C   A 1 47  ? 5.313   68.624  53.206  1.00 38.53  ? 548  C   C C2    1 
ATOM   996   O  O2    . C   A 1 47  ? 6.456   69.074  53.062  1.00 38.78  ? 548  C   C O2    1 
ATOM   997   N  N3    . C   A 1 47  ? 4.631   68.070  52.177  1.00 50.31  ? 548  C   C N3    1 
ATOM   998   C  C4    . C   A 1 47  ? 3.387   67.622  52.373  1.00 55.57  ? 548  C   C C4    1 
ATOM   999   N  N4    . C   A 1 47  ? 2.760   67.048  51.343  1.00 48.19  ? 548  C   C N4    1 
ATOM   1000  C  C5    . C   A 1 47  ? 2.734   67.737  53.641  1.00 54.51  ? 548  C   C C5    1 
ATOM   1001  C  C6    . C   A 1 47  ? 3.429   68.283  54.649  1.00 45.29  ? 548  C   C C6    1 
ATOM   1002  P  P     . G   A 1 48  ? 7.311   72.404  58.441  1.00 65.52  ? 549  G   C P     1 
ATOM   1003  O  OP1   . G   A 1 48  ? 6.766   73.347  57.435  1.00 65.49  ? 549  G   C OP1   1 
ATOM   1004  O  OP2   . G   A 1 48  ? 8.719   72.526  58.875  1.00 54.14  ? 549  G   C OP2   1 
ATOM   1005  O  "O5'" . G   A 1 48  ? 6.400   72.475  59.738  1.00 70.21  ? 549  G   C "O5'" 1 
ATOM   1006  C  "C5'" . G   A 1 48  ? 6.551   71.534  60.790  1.00 71.75  ? 549  G   C "C5'" 1 
ATOM   1007  C  "C4'" . G   A 1 48  ? 6.310   72.213  62.114  1.00 74.72  ? 549  G   C "C4'" 1 
ATOM   1008  O  "O4'" . G   A 1 48  ? 7.465   73.020  62.474  1.00 69.83  ? 549  G   C "O4'" 1 
ATOM   1009  C  "C3'" . G   A 1 48  ? 5.148   73.193  62.102  1.00 75.07  ? 549  G   C "C3'" 1 
ATOM   1010  O  "O3'" . G   A 1 48  ? 3.899   72.544  62.306  1.00 73.61  ? 549  G   C "O3'" 1 
ATOM   1011  C  "C2'" . G   A 1 48  ? 5.518   74.129  63.241  1.00 79.14  ? 549  G   C "C2'" 1 
ATOM   1012  O  "O2'" . G   A 1 48  ? 5.231   73.567  64.506  1.00 86.01  ? 549  G   C "O2'" 1 
ATOM   1013  C  "C1'" . G   A 1 48  ? 7.032   74.248  63.037  1.00 76.81  ? 549  G   C "C1'" 1 
ATOM   1014  N  N9    . G   A 1 48  ? 7.367   75.309  62.093  1.00 77.45  ? 549  G   C N9    1 
ATOM   1015  C  C8    . G   A 1 48  ? 7.953   75.154  60.862  1.00 71.43  ? 549  G   C C8    1 
ATOM   1016  N  N7    . G   A 1 48  ? 8.105   76.279  60.219  1.00 69.06  ? 549  G   C N7    1 
ATOM   1017  C  C5    . G   A 1 48  ? 7.592   77.242  61.078  1.00 78.08  ? 549  G   C C5    1 
ATOM   1018  C  C6    . G   A 1 48  ? 7.479   78.650  60.920  1.00 72.07  ? 549  G   C C6    1 
ATOM   1019  O  O6    . G   A 1 48  ? 7.820   79.343  59.958  1.00 68.56  ? 549  G   C O6    1 
ATOM   1020  N  N1    . G   A 1 48  ? 6.896   79.247  62.036  1.00 68.48  ? 549  G   C N1    1 
ATOM   1021  C  C2    . G   A 1 48  ? 6.479   78.583  63.164  1.00 68.92  ? 549  G   C C2    1 
ATOM   1022  N  N2    . G   A 1 48  ? 5.943   79.341  64.128  1.00 56.49  ? 549  G   C N2    1 
ATOM   1023  N  N3    . G   A 1 48  ? 6.580   77.267  63.329  1.00 81.13  ? 549  G   C N3    1 
ATOM   1024  C  C4    . G   A 1 48  ? 7.140   76.663  62.248  1.00 83.22  ? 549  G   C C4    1 
ATOM   1025  P  P     . G   A 1 49  ? 2.576   73.152  61.631  1.00 78.27  ? 550  G   C P     1 
ATOM   1026  O  OP1   . G   A 1 49  ? 1.446   72.221  61.871  1.00 81.76  ? 550  G   C OP1   1 
ATOM   1027  O  OP2   . G   A 1 49  ? 2.934   73.521  60.236  1.00 85.20  ? 550  G   C OP2   1 
ATOM   1028  O  "O5'" . G   A 1 49  ? 2.322   74.492  62.456  1.00 80.60  ? 550  G   C "O5'" 1 
ATOM   1029  C  "C5'" . G   A 1 49  ? 2.094   74.449  63.861  1.00 80.60  ? 550  G   C "C5'" 1 
ATOM   1030  C  "C4'" . G   A 1 49  ? 1.748   75.823  64.385  1.00 85.07  ? 550  G   C "C4'" 1 
ATOM   1031  O  "O4'" . G   A 1 49  ? 2.925   76.677  64.389  1.00 87.20  ? 550  G   C "O4'" 1 
ATOM   1032  C  "C3'" . G   A 1 49  ? 0.746   76.609  63.563  1.00 85.82  ? 550  G   C "C3'" 1 
ATOM   1033  O  "O3'" . G   A 1 49  ? -0.588  76.220  63.824  1.00 99.30  ? 550  G   C "O3'" 1 
ATOM   1034  C  "C2'" . G   A 1 49  ? 1.014   78.024  64.041  1.00 87.34  ? 550  G   C "C2'" 1 
ATOM   1035  O  "O2'" . G   A 1 49  ? 0.465   78.256  65.320  1.00 84.85  ? 550  G   C "O2'" 1 
ATOM   1036  C  "C1'" . G   A 1 49  ? 2.541   78.019  64.106  1.00 86.12  ? 550  G   C "C1'" 1 
ATOM   1037  N  N9    . G   A 1 49  ? 3.126   78.402  62.823  1.00 87.91  ? 550  G   C N9    1 
ATOM   1038  C  C8    . G   A 1 49  ? 3.578   77.557  61.837  1.00 90.48  ? 550  G   C C8    1 
ATOM   1039  N  N7    . G   A 1 49  ? 4.047   78.188  60.793  1.00 89.10  ? 550  G   C N7    1 
ATOM   1040  C  C5    . G   A 1 49  ? 3.899   79.531  61.108  1.00 86.92  ? 550  G   C C5    1 
ATOM   1041  C  C6    . G   A 1 49  ? 4.241   80.693  60.364  1.00 86.67  ? 550  G   C C6    1 
ATOM   1042  O  O6    . G   A 1 49  ? 4.776   80.770  59.247  1.00 81.72  ? 550  G   C O6    1 
ATOM   1043  N  N1    . G   A 1 49  ? 3.903   81.854  61.051  1.00 88.31  ? 550  G   C N1    1 
ATOM   1044  C  C2    . G   A 1 49  ? 3.320   81.898  62.293  1.00 88.94  ? 550  G   C C2    1 
ATOM   1045  N  N2    . G   A 1 49  ? 3.057   83.118  62.774  1.00 84.43  ? 550  G   C N2    1 
ATOM   1046  N  N3    . G   A 1 49  ? 3.014   80.824  63.007  1.00 88.39  ? 550  G   C N3    1 
ATOM   1047  C  C4    . G   A 1 49  ? 3.326   79.682  62.356  1.00 89.06  ? 550  G   C C4    1 
ATOM   1048  P  P     . G   A 1 50  ? -1.728  76.521  62.729  1.00 106.96 ? 551  G   C P     1 
ATOM   1049  O  OP1   . G   A 1 50  ? -2.995  75.929  63.232  1.00 110.65 ? 551  G   C OP1   1 
ATOM   1050  O  OP2   . G   A 1 50  ? -1.210  76.115  61.393  1.00 102.19 ? 551  G   C OP2   1 
ATOM   1051  O  "O5'" . G   A 1 50  ? -1.869  78.109  62.751  1.00 103.58 ? 551  G   C "O5'" 1 
ATOM   1052  C  "C5'" . G   A 1 50  ? -2.282  78.790  63.935  1.00 102.62 ? 551  G   C "C5'" 1 
ATOM   1053  C  "C4'" . G   A 1 50  ? -2.269  80.286  63.710  1.00 102.52 ? 551  G   C "C4'" 1 
ATOM   1054  O  "O4'" . G   A 1 50  ? -0.901  80.769  63.589  1.00 104.04 ? 551  G   C "O4'" 1 
ATOM   1055  C  "C3'" . G   A 1 50  ? -2.925  80.737  62.421  1.00 100.70 ? 551  G   C "C3'" 1 
ATOM   1056  O  "O3'" . G   A 1 50  ? -4.329  80.810  62.542  1.00 102.75 ? 551  G   C "O3'" 1 
ATOM   1057  C  "C2'" . G   A 1 50  ? -2.287  82.099  62.201  1.00 100.54 ? 551  G   C "C2'" 1 
ATOM   1058  O  "O2'" . G   A 1 50  ? -2.847  83.111  63.011  1.00 90.76  ? 551  G   C "O2'" 1 
ATOM   1059  C  "C1'" . G   A 1 50  ? -0.844  81.806  62.616  1.00 103.35 ? 551  G   C "C1'" 1 
ATOM   1060  N  N9    . G   A 1 50  ? -0.056  81.330  61.480  1.00 106.13 ? 551  G   C N9    1 
ATOM   1061  C  C8    . G   A 1 50  ? 0.240   80.025  61.155  1.00 105.24 ? 551  G   C C8    1 
ATOM   1062  N  N7    . G   A 1 50  ? 0.937   79.915  60.055  1.00 102.01 ? 551  G   C N7    1 
ATOM   1063  C  C5    . G   A 1 50  ? 1.120   81.225  59.634  1.00 103.44 ? 551  G   C C5    1 
ATOM   1064  C  C6    . G   A 1 50  ? 1.798   81.740  58.499  1.00 102.62 ? 551  G   C C6    1 
ATOM   1065  O  O6    . G   A 1 50  ? 2.398   81.122  57.609  1.00 100.06 ? 551  G   C O6    1 
ATOM   1066  N  N1    . G   A 1 50  ? 1.735   83.128  58.456  1.00 102.53 ? 551  G   C N1    1 
ATOM   1067  C  C2    . G   A 1 50  ? 1.107   83.921  59.385  1.00 102.73 ? 551  G   C C2    1 
ATOM   1068  N  N2    . G   A 1 50  ? 1.159   85.245  59.167  1.00 103.82 ? 551  G   C N2    1 
ATOM   1069  N  N3    . G   A 1 50  ? 0.476   83.456  60.446  1.00 99.60  ? 551  G   C N3    1 
ATOM   1070  C  C4    . G   A 1 50  ? 0.520   82.110  60.507  1.00 104.02 ? 551  G   C C4    1 
ATOM   1071  P  P     . G   A 1 51  ? -5.222  80.944  61.219  1.00 107.49 ? 552  G   C P     1 
ATOM   1072  O  OP1   . G   A 1 51  ? -6.599  80.487  61.540  1.00 107.12 ? 552  G   C OP1   1 
ATOM   1073  O  OP2   . G   A 1 51  ? -4.481  80.321  60.094  1.00 100.69 ? 552  G   C OP2   1 
ATOM   1074  O  "O5'" . G   A 1 51  ? -5.252  82.509  60.945  1.00 107.81 ? 552  G   C "O5'" 1 
ATOM   1075  C  "C5'" . G   A 1 51  ? -5.671  83.003  59.686  1.00 108.32 ? 552  G   C "C5'" 1 
ATOM   1076  C  "C4'" . G   A 1 51  ? -5.018  84.328  59.404  1.00 107.35 ? 552  G   C "C4'" 1 
ATOM   1077  O  "O4'" . G   A 1 51  ? -3.605  84.254  59.729  1.00 110.32 ? 552  G   C "O4'" 1 
ATOM   1078  C  "C3'" . G   A 1 51  ? -5.056  84.712  57.938  1.00 108.67 ? 552  G   C "C3'" 1 
ATOM   1079  O  "O3'" . G   A 1 51  ? -6.290  85.329  57.621  1.00 107.79 ? 552  G   C "O3'" 1 
ATOM   1080  C  "C2'" . G   A 1 51  ? -3.849  85.626  57.818  1.00 107.70 ? 552  G   C "C2'" 1 
ATOM   1081  O  "O2'" . G   A 1 51  ? -4.089  86.920  58.331  1.00 106.17 ? 552  G   C "O2'" 1 
ATOM   1082  C  "C1'" . G   A 1 51  ? -2.848  84.884  58.706  1.00 109.28 ? 552  G   C "C1'" 1 
ATOM   1083  N  N9    . G   A 1 51  ? -2.131  83.839  57.980  1.00 107.76 ? 552  G   C N9    1 
ATOM   1084  C  C8    . G   A 1 51  ? -2.172  82.485  58.222  1.00 103.62 ? 552  G   C C8    1 
ATOM   1085  N  N7    . G   A 1 51  ? -1.437  81.795  57.394  1.00 102.65 ? 552  G   C N7    1 
ATOM   1086  C  C5    . G   A 1 51  ? -0.872  82.748  56.558  1.00 105.06 ? 552  G   C C5    1 
ATOM   1087  C  C6    . G   A 1 51  ? 0.017   82.600  55.459  1.00 104.72 ? 552  G   C C6    1 
ATOM   1088  O  O6    . G   A 1 51  ? 0.499   81.563  54.992  1.00 105.29 ? 552  G   C O6    1 
ATOM   1089  N  N1    . G   A 1 51  ? 0.335   83.828  54.888  1.00 103.16 ? 552  G   C N1    1 
ATOM   1090  C  C2    . G   A 1 51  ? -0.138  85.042  55.314  1.00 102.49 ? 552  G   C C2    1 
ATOM   1091  N  N2    . G   A 1 51  ? 0.283   86.109  54.625  1.00 96.78  ? 552  G   C N2    1 
ATOM   1092  N  N3    . G   A 1 51  ? -0.964  85.197  56.337  1.00 103.09 ? 552  G   C N3    1 
ATOM   1093  C  C4    . G   A 1 51  ? -1.287  84.015  56.908  1.00 106.08 ? 552  G   C C4    1 
ATOM   1094  P  P     . G   A 1 52  ? -7.370  84.521  56.750  1.00 111.17 ? 553  G   C P     1 
ATOM   1095  O  OP1   . G   A 1 52  ? -8.690  85.176  56.946  1.00 111.35 ? 553  G   C OP1   1 
ATOM   1096  O  OP2   . G   A 1 52  ? -7.213  83.076  57.069  1.00 103.56 ? 553  G   C OP2   1 
ATOM   1097  O  "O5'" . G   A 1 52  ? -6.917  84.809  55.252  1.00 105.86 ? 553  G   C "O5'" 1 
ATOM   1098  C  "C5'" . G   A 1 52  ? -7.106  86.107  54.710  1.00 98.80  ? 553  G   C "C5'" 1 
ATOM   1099  C  "C4'" . G   A 1 52  ? -5.875  86.571  53.974  1.00 95.91  ? 553  G   C "C4'" 1 
ATOM   1100  O  "O4'" . G   A 1 52  ? -4.669  86.027  54.576  1.00 98.25  ? 553  G   C "O4'" 1 
ATOM   1101  C  "C3'" . G   A 1 52  ? -5.779  86.114  52.537  1.00 95.25  ? 553  G   C "C3'" 1 
ATOM   1102  O  "O3'" . G   A 1 52  ? -6.617  86.951  51.761  1.00 93.94  ? 553  G   C "O3'" 1 
ATOM   1103  C  "C2'" . G   A 1 52  ? -4.293  86.313  52.243  1.00 93.73  ? 553  G   C "C2'" 1 
ATOM   1104  O  "O2'" . G   A 1 52  ? -3.933  87.649  51.963  1.00 76.55  ? 553  G   C "O2'" 1 
ATOM   1105  C  "C1'" . G   A 1 52  ? -3.660  85.900  53.576  1.00 96.05  ? 553  G   C "C1'" 1 
ATOM   1106  N  N9    . G   A 1 52  ? -3.168  84.522  53.558  1.00 97.75  ? 553  G   C N9    1 
ATOM   1107  C  C8    . G   A 1 52  ? -3.427  83.533  54.476  1.00 98.56  ? 553  G   C C8    1 
ATOM   1108  N  N7    . G   A 1 52  ? -2.873  82.392  54.170  1.00 94.96  ? 553  G   C N7    1 
ATOM   1109  C  C5    . G   A 1 52  ? -2.202  82.641  52.980  1.00 93.79  ? 553  G   C C5    1 
ATOM   1110  C  C6    . G   A 1 52  ? -1.433  81.775  52.160  1.00 94.69  ? 553  G   C C6    1 
ATOM   1111  O  O6    . G   A 1 52  ? -1.189  80.576  52.321  1.00 101.30 ? 553  G   C O6    1 
ATOM   1112  N  N1    . G   A 1 52  ? -0.929  82.438  51.048  1.00 90.69  ? 553  G   C N1    1 
ATOM   1113  C  C2    . G   A 1 52  ? -1.139  83.760  50.755  1.00 87.36  ? 553  G   C C2    1 
ATOM   1114  N  N2    . G   A 1 52  ? -0.563  84.215  49.632  1.00 74.03  ? 553  G   C N2    1 
ATOM   1115  N  N3    . G   A 1 52  ? -1.860  84.576  51.507  1.00 91.27  ? 553  G   C N3    1 
ATOM   1116  C  C4    . G   A 1 52  ? -2.359  83.953  52.596  1.00 93.26  ? 553  G   C C4    1 
ATOM   1117  P  P     . U   A 1 53  ? -7.641  86.299  50.714  1.00 98.95  ? 554  U   C P     1 
ATOM   1118  O  OP1   . U   A 1 53  ? -8.675  87.325  50.400  1.00 95.66  ? 554  U   C OP1   1 
ATOM   1119  O  OP2   . U   A 1 53  ? -8.056  84.968  51.228  1.00 85.64  ? 554  U   C OP2   1 
ATOM   1120  O  "O5'" . U   A 1 53  ? -6.730  86.097  49.428  1.00 91.30  ? 554  U   C "O5'" 1 
ATOM   1121  C  "C5'" . U   A 1 53  ? -5.894  87.153  48.977  1.00 90.52  ? 554  U   C "C5'" 1 
ATOM   1122  C  "C4'" . U   A 1 53  ? -4.908  86.631  47.974  1.00 94.84  ? 554  U   C "C4'" 1 
ATOM   1123  O  "O4'" . U   A 1 53  ? -3.837  85.919  48.646  1.00 94.99  ? 554  U   C "O4'" 1 
ATOM   1124  C  "C3'" . U   A 1 53  ? -5.513  85.604  47.041  1.00 95.82  ? 554  U   C "C3'" 1 
ATOM   1125  O  "O3'" . U   A 1 53  ? -6.247  86.234  46.002  1.00 94.09  ? 554  U   C "O3'" 1 
ATOM   1126  C  "C2'" . U   A 1 53  ? -4.285  84.826  46.584  1.00 96.36  ? 554  U   C "C2'" 1 
ATOM   1127  O  "O2'" . U   A 1 53  ? -3.536  85.473  45.575  1.00 95.86  ? 554  U   C "O2'" 1 
ATOM   1128  C  "C1'" . U   A 1 53  ? -3.474  84.781  47.879  1.00 99.05  ? 554  U   C "C1'" 1 
ATOM   1129  N  N1    . U   A 1 53  ? -3.740  83.577  48.682  1.00 100.39 ? 554  U   C N1    1 
ATOM   1130  C  C2    . U   A 1 53  ? -3.225  82.383  48.219  1.00 99.08  ? 554  U   C C2    1 
ATOM   1131  O  O2    . U   A 1 53  ? -2.611  82.295  47.169  1.00 98.92  ? 554  U   C O2    1 
ATOM   1132  N  N3    . U   A 1 53  ? -3.463  81.295  49.027  1.00 96.10  ? 554  U   C N3    1 
ATOM   1133  C  C4    . U   A 1 53  ? -4.159  81.281  50.217  1.00 95.58  ? 554  U   C C4    1 
ATOM   1134  O  O4    . U   A 1 53  ? -4.234  80.233  50.859  1.00 95.23  ? 554  U   C O4    1 
ATOM   1135  C  C5    . U   A 1 53  ? -4.688  82.553  50.617  1.00 92.61  ? 554  U   C C5    1 
ATOM   1136  C  C6    . U   A 1 53  ? -4.465  83.631  49.857  1.00 96.66  ? 554  U   C C6    1 
ATOM   1137  P  P     . U   A 1 54  ? -7.823  85.954  45.871  1.00 94.38  ? 555  U   C P     1 
ATOM   1138  O  OP1   . U   A 1 54  ? -8.387  86.912  44.884  1.00 92.19  ? 555  U   C OP1   1 
ATOM   1139  O  OP2   . U   A 1 54  ? -8.371  85.903  47.255  1.00 77.74  ? 555  U   C OP2   1 
ATOM   1140  O  "O5'" . U   A 1 54  ? -7.897  84.496  45.232  1.00 95.41  ? 555  U   C "O5'" 1 
ATOM   1141  C  "C5'" . U   A 1 54  ? -7.211  84.206  44.016  1.00 100.37 ? 555  U   C "C5'" 1 
ATOM   1142  C  "C4'" . U   A 1 54  ? -6.952  82.719  43.888  1.00 103.62 ? 555  U   C "C4'" 1 
ATOM   1143  O  "O4'" . U   A 1 54  ? -6.064  82.265  44.952  1.00 105.31 ? 555  U   C "O4'" 1 
ATOM   1144  C  "C3'" . U   A 1 54  ? -8.159  81.810  44.036  1.00 102.53 ? 555  U   C "C3'" 1 
ATOM   1145  O  "O3'" . U   A 1 54  ? -8.932  81.767  42.843  1.00 96.14  ? 555  U   C "O3'" 1 
ATOM   1146  C  "C2'" . U   A 1 54  ? -7.496  80.470  44.346  1.00 103.85 ? 555  U   C "C2'" 1 
ATOM   1147  O  "O2'" . U   A 1 54  ? -6.966  79.827  43.201  1.00 102.89 ? 555  U   C "O2'" 1 
ATOM   1148  C  "C1'" . U   A 1 54  ? -6.348  80.907  45.260  1.00 98.68  ? 555  U   C "C1'" 1 
ATOM   1149  N  N1    . U   A 1 54  ? -6.709  80.799  46.682  1.00 94.81  ? 555  U   C N1    1 
ATOM   1150  C  C2    . U   A 1 54  ? -6.423  79.605  47.311  1.00 96.97  ? 555  U   C C2    1 
ATOM   1151  O  O2    . U   A 1 54  ? -5.842  78.689  46.750  1.00 98.73  ? 555  U   C O2    1 
ATOM   1152  N  N3    . U   A 1 54  ? -6.838  79.521  48.620  1.00 94.51  ? 555  U   C N3    1 
ATOM   1153  C  C4    . U   A 1 54  ? -7.486  80.491  49.351  1.00 89.51  ? 555  U   C C4    1 
ATOM   1154  O  O4    . U   A 1 54  ? -7.881  80.224  50.487  1.00 89.21  ? 555  U   C O4    1 
ATOM   1155  C  C5    . U   A 1 54  ? -7.715  81.715  48.641  1.00 89.10  ? 555  U   C C5    1 
ATOM   1156  C  C6    . U   A 1 54  ? -7.329  81.825  47.361  1.00 89.42  ? 555  U   C C6    1 
ATOM   1157  P  P     . C   A 1 55  ? -10.537 81.712  42.943  1.00 92.82  ? 556  C   C P     1 
ATOM   1158  O  OP1   . C   A 1 55  ? -11.093 81.717  41.563  1.00 84.17  ? 556  C   C OP1   1 
ATOM   1159  O  OP2   . C   A 1 55  ? -10.952 82.756  43.915  1.00 89.38  ? 556  C   C OP2   1 
ATOM   1160  O  "O5'" . C   A 1 55  ? -10.843 80.301  43.611  1.00 90.67  ? 556  C   C "O5'" 1 
ATOM   1161  C  "C5'" . C   A 1 55  ? -12.117 80.024  44.171  1.00 86.64  ? 556  C   C "C5'" 1 
ATOM   1162  C  "C4'" . C   A 1 55  ? -12.292 78.537  44.354  1.00 92.96  ? 556  C   C "C4'" 1 
ATOM   1163  O  "O4'" . C   A 1 55  ? -12.261 77.877  43.061  1.00 94.42  ? 556  C   C "O4'" 1 
ATOM   1164  C  "C3'" . C   A 1 55  ? -11.199 77.835  45.139  1.00 87.98  ? 556  C   C "C3'" 1 
ATOM   1165  O  "O3'" . C   A 1 55  ? -11.423 77.982  46.532  1.00 95.07  ? 556  C   C "O3'" 1 
ATOM   1166  C  "C2'" . C   A 1 55  ? -11.362 76.389  44.684  1.00 87.19  ? 556  C   C "C2'" 1 
ATOM   1167  O  "O2'" . C   A 1 55  ? -12.425 75.714  45.326  1.00 78.89  ? 556  C   C "O2'" 1 
ATOM   1168  C  "C1'" . C   A 1 55  ? -11.701 76.579  43.205  1.00 90.89  ? 556  C   C "C1'" 1 
ATOM   1169  N  N1    . C   A 1 55  ? -10.527 76.488  42.329  1.00 95.32  ? 556  C   C N1    1 
ATOM   1170  C  C2    . C   A 1 55  ? -10.056 75.220  41.958  1.00 94.52  ? 556  C   C C2    1 
ATOM   1171  O  O2    . C   A 1 55  ? -10.641 74.208  42.391  1.00 89.86  ? 556  C   C O2    1 
ATOM   1172  N  N3    . C   A 1 55  ? -8.978  75.132  41.141  1.00 94.98  ? 556  C   C N3    1 
ATOM   1173  C  C4    . C   A 1 55  ? -8.379  76.244  40.702  1.00 96.58  ? 556  C   C C4    1 
ATOM   1174  N  N4    . C   A 1 55  ? -7.322  76.110  39.897  1.00 97.90  ? 556  C   C N4    1 
ATOM   1175  C  C5    . C   A 1 55  ? -8.837  77.544  41.067  1.00 94.58  ? 556  C   C C5    1 
ATOM   1176  C  C6    . C   A 1 55  ? -9.903  77.619  41.875  1.00 94.38  ? 556  C   C C6    1 
ATOM   1177  P  P     . G   A 1 56  ? -10.207 78.413  47.481  1.00 95.42  ? 557  G   C P     1 
ATOM   1178  O  OP1   . G   A 1 56  ? -10.697 78.630  48.872  1.00 98.60  ? 557  G   C OP1   1 
ATOM   1179  O  OP2   . G   A 1 56  ? -9.507  79.510  46.768  1.00 93.89  ? 557  G   C OP2   1 
ATOM   1180  O  "O5'" . G   A 1 56  ? -9.263  77.129  47.474  1.00 102.90 ? 557  G   C "O5'" 1 
ATOM   1181  C  "C5'" . G   A 1 56  ? -9.683  75.899  48.070  1.00 98.44  ? 557  G   C "C5'" 1 
ATOM   1182  C  "C4'" . G   A 1 56  ? -8.690  74.799  47.758  1.00 94.46  ? 557  G   C "C4'" 1 
ATOM   1183  O  "O4'" . G   A 1 56  ? -8.716  74.516  46.335  1.00 95.46  ? 557  G   C "O4'" 1 
ATOM   1184  C  "C3'" . G   A 1 56  ? -7.236  75.139  48.020  1.00 88.06  ? 557  G   C "C3'" 1 
ATOM   1185  O  "O3'" . G   A 1 56  ? -6.877  74.970  49.377  1.00 83.59  ? 557  G   C "O3'" 1 
ATOM   1186  C  "C2'" . G   A 1 56  ? -6.514  74.152  47.124  1.00 89.43  ? 557  G   C "C2'" 1 
ATOM   1187  O  "O2'" . G   A 1 56  ? -6.489  72.854  47.675  1.00 97.69  ? 557  G   C "O2'" 1 
ATOM   1188  C  "C1'" . G   A 1 56  ? -7.417  74.165  45.895  1.00 91.83  ? 557  G   C "C1'" 1 
ATOM   1189  N  N9    . G   A 1 56  ? -6.981  75.149  44.912  1.00 94.26  ? 557  G   C N9    1 
ATOM   1190  C  C8    . G   A 1 56  ? -7.515  76.389  44.658  1.00 93.25  ? 557  G   C C8    1 
ATOM   1191  N  N7    . G   A 1 56  ? -6.877  77.038  43.721  1.00 92.50  ? 557  G   C N7    1 
ATOM   1192  C  C5    . G   A 1 56  ? -5.865  76.171  43.335  1.00 92.91  ? 557  G   C C5    1 
ATOM   1193  C  C6    . G   A 1 56  ? -4.842  76.319  42.363  1.00 91.77  ? 557  G   C C6    1 
ATOM   1194  O  O6    . G   A 1 56  ? -4.604  77.290  41.627  1.00 85.33  ? 557  G   C O6    1 
ATOM   1195  N  N1    . G   A 1 56  ? -4.039  75.183  42.296  1.00 93.07  ? 557  G   C N1    1 
ATOM   1196  C  C2    . G   A 1 56  ? -4.194  74.058  43.073  1.00 92.44  ? 557  G   C C2    1 
ATOM   1197  N  N2    . G   A 1 56  ? -3.335  73.061  42.869  1.00 86.02  ? 557  G   C N2    1 
ATOM   1198  N  N3    . G   A 1 56  ? -5.128  73.919  43.985  1.00 96.29  ? 557  G   C N3    1 
ATOM   1199  C  C4    . G   A 1 56  ? -5.924  75.001  44.061  1.00 96.04  ? 557  G   C C4    1 
ATOM   1200  P  P     . A   A 1 57  ? -5.892  76.032  50.041  1.00 89.01  ? 558  A   C P     1 
ATOM   1201  O  OP1   . A   A 1 57  ? -6.681  77.215  50.472  1.00 102.19 ? 558  A   C OP1   1 
ATOM   1202  O  OP2   . A   A 1 57  ? -4.797  76.203  49.058  1.00 86.38  ? 558  A   C OP2   1 
ATOM   1203  O  "O5'" . A   A 1 57  ? -5.322  75.311  51.337  1.00 93.69  ? 558  A   C "O5'" 1 
ATOM   1204  C  "C5'" . A   A 1 57  ? -3.991  75.568  51.784  1.00 98.55  ? 558  A   C "C5'" 1 
ATOM   1205  C  "C4'" . A   A 1 57  ? -3.073  74.454  51.326  1.00 98.56  ? 558  A   C "C4'" 1 
ATOM   1206  O  "O4'" . A   A 1 57  ? -2.775  74.633  49.905  1.00 94.32  ? 558  A   C "O4'" 1 
ATOM   1207  C  "C3'" . A   A 1 57  ? -1.717  74.441  52.003  1.00 94.16  ? 558  A   C "C3'" 1 
ATOM   1208  O  "O3'" . A   A 1 57  ? -1.410  73.480  53.008  1.00 85.18  ? 558  A   C "O3'" 1 
ATOM   1209  C  "C2'" . A   A 1 57  ? -0.717  75.098  51.069  1.00 95.60  ? 558  A   C "C2'" 1 
ATOM   1210  O  "O2'" . A   A 1 57  ? 0.446   74.314  50.940  1.00 111.39 ? 558  A   C "O2'" 1 
ATOM   1211  C  "C1'" . A   A 1 57  ? -1.430  75.050  49.720  1.00 94.24  ? 558  A   C "C1'" 1 
ATOM   1212  N  N9    . A   A 1 57  ? -1.418  76.378  49.102  1.00 98.78  ? 558  A   C N9    1 
ATOM   1213  C  C8    . A   A 1 57  ? -2.012  77.528  49.568  1.00 100.71 ? 558  A   C C8    1 
ATOM   1214  N  N7    . A   A 1 57  ? -1.789  78.582  48.818  1.00 97.72  ? 558  A   C N7    1 
ATOM   1215  C  C5    . A   A 1 57  ? -1.005  78.094  47.783  1.00 97.83  ? 558  A   C C5    1 
ATOM   1216  C  C6    . A   A 1 57  ? -0.434  78.713  46.653  1.00 97.43  ? 558  A   C C6    1 
ATOM   1217  N  N6    . A   A 1 57  ? -0.574  80.006  46.364  1.00 94.73  ? 558  A   C N6    1 
ATOM   1218  N  N1    . A   A 1 57  ? 0.297   77.944  45.820  1.00 98.42  ? 558  A   C N1    1 
ATOM   1219  C  C2    . A   A 1 57  ? 0.437   76.645  46.107  1.00 101.37 ? 558  A   C C2    1 
ATOM   1220  N  N3    . A   A 1 57  ? -0.053  75.947  47.132  1.00 102.19 ? 558  A   C N3    1 
ATOM   1221  C  C4    . A   A 1 57  ? -0.772  76.738  47.943  1.00 98.77  ? 558  A   C C4    1 
ATOM   1222  P  P     . U   A 1 58  ? -0.845  72.042  52.587  1.00 79.65  ? 559  U   C P     1 
ATOM   1223  O  OP1   . U   A 1 58  ? -1.424  71.675  51.261  1.00 75.21  ? 559  U   C OP1   1 
ATOM   1224  O  OP2   . U   A 1 58  ? -1.062  71.157  53.756  1.00 87.39  ? 559  U   C OP2   1 
ATOM   1225  O  "O5'" . U   A 1 58  ? 0.724   72.247  52.409  1.00 77.29  ? 559  U   C "O5'" 1 
ATOM   1226  C  "C5'" . U   A 1 58  ? 1.572   72.466  53.528  1.00 65.83  ? 559  U   C "C5'" 1 
ATOM   1227  C  "C4'" . U   A 1 58  ? 3.005   72.500  53.071  1.00 62.28  ? 559  U   C "C4'" 1 
ATOM   1228  O  "O4'" . U   A 1 58  ? 3.357   71.197  52.558  1.00 55.78  ? 559  U   C "O4'" 1 
ATOM   1229  C  "C3'" . U   A 1 58  ? 3.284   73.449  51.916  1.00 58.46  ? 559  U   C "C3'" 1 
ATOM   1230  O  "O3'" . U   A 1 58  ? 3.596   74.734  52.432  1.00 59.11  ? 559  U   C "O3'" 1 
ATOM   1231  C  "C2'" . U   A 1 58  ? 4.518   72.831  51.273  1.00 59.75  ? 559  U   C "C2'" 1 
ATOM   1232  O  "O2'" . U   A 1 58  ? 5.715   73.188  51.941  1.00 51.10  ? 559  U   C "O2'" 1 
ATOM   1233  C  "C1'" . U   A 1 58  ? 4.249   71.338  51.466  1.00 55.38  ? 559  U   C "C1'" 1 
ATOM   1234  N  N1    . U   A 1 58  ? 3.644   70.683  50.300  1.00 59.21  ? 559  U   C N1    1 
ATOM   1235  C  C2    . U   A 1 58  ? 4.425   70.503  49.173  1.00 55.00  ? 559  U   C C2    1 
ATOM   1236  O  O2    . U   A 1 58  ? 5.592   70.867  49.104  1.00 54.18  ? 559  U   C O2    1 
ATOM   1237  N  N3    . U   A 1 58  ? 3.791   69.879  48.130  1.00 43.14  ? 559  U   C N3    1 
ATOM   1238  C  C4    . U   A 1 58  ? 2.487   69.413  48.104  1.00 52.03  ? 559  U   C C4    1 
ATOM   1239  O  O4    . U   A 1 58  ? 2.063   68.819  47.099  1.00 49.37  ? 559  U   C O4    1 
ATOM   1240  C  C5    . U   A 1 58  ? 1.754   69.641  49.307  1.00 47.03  ? 559  U   C C5    1 
ATOM   1241  C  C6    . U   A 1 58  ? 2.338   70.255  50.333  1.00 58.93  ? 559  U   C C6    1 
ATOM   1242  P  P     . U   A 1 59  ? 3.262   76.053  51.579  1.00 56.69  ? 560  U   C P     1 
ATOM   1243  O  OP1   . U   A 1 59  ? 3.944   77.131  52.337  1.00 58.82  ? 560  U   C OP1   1 
ATOM   1244  O  OP2   . U   A 1 59  ? 1.802   76.121  51.369  1.00 59.48  ? 560  U   C OP2   1 
ATOM   1245  O  "O5'" . U   A 1 59  ? 3.989   75.850  50.170  1.00 47.52  ? 560  U   C "O5'" 1 
ATOM   1246  C  "C5'" . U   A 1 59  ? 5.405   75.935  50.091  1.00 53.00  ? 560  U   C "C5'" 1 
ATOM   1247  C  "C4'" . U   A 1 59  ? 5.903   75.641  48.696  1.00 51.51  ? 560  U   C "C4'" 1 
ATOM   1248  O  "O4'" . U   A 1 59  ? 5.347   74.382  48.250  1.00 54.21  ? 560  U   C "O4'" 1 
ATOM   1249  C  "C3'" . U   A 1 59  ? 5.437   76.687  47.687  1.00 58.74  ? 560  U   C "C3'" 1 
ATOM   1250  O  "O3'" . U   A 1 59  ? 6.487   77.149  46.838  1.00 56.19  ? 560  U   C "O3'" 1 
ATOM   1251  C  "C2'" . U   A 1 59  ? 4.221   76.088  46.984  1.00 56.59  ? 560  U   C "C2'" 1 
ATOM   1252  O  "O2'" . U   A 1 59  ? 4.207   76.320  45.588  1.00 58.77  ? 560  U   C "O2'" 1 
ATOM   1253  C  "C1'" . U   A 1 59  ? 4.472   74.593  47.167  1.00 55.06  ? 560  U   C "C1'" 1 
ATOM   1254  N  N1    . U   A 1 59  ? 3.294   73.736  47.294  1.00 54.45  ? 560  U   C N1    1 
ATOM   1255  C  C2    . U   A 1 59  ? 2.993   72.931  46.211  1.00 58.45  ? 560  U   C C2    1 
ATOM   1256  O  O2    . U   A 1 59  ? 3.680   72.898  45.201  1.00 48.90  ? 560  U   C O2    1 
ATOM   1257  N  N3    . U   A 1 59  ? 1.859   72.172  46.352  1.00 59.75  ? 560  U   C N3    1 
ATOM   1258  C  C4    . U   A 1 59  ? 1.018   72.145  47.439  1.00 59.81  ? 560  U   C C4    1 
ATOM   1259  O  O4    . U   A 1 59  ? 0.011   71.436  47.409  1.00 75.30  ? 560  U   C O4    1 
ATOM   1260  C  C5    . U   A 1 59  ? 1.413   72.992  48.521  1.00 61.07  ? 560  U   C C5    1 
ATOM   1261  C  C6    . U   A 1 59  ? 2.514   73.739  48.414  1.00 51.93  ? 560  U   C C6    1 
ATOM   1262  P  P     . C   A 1 60  ? 7.325   78.458  47.222  1.00 63.90  ? 561  C   C P     1 
ATOM   1263  O  OP1   . C   A 1 60  ? 8.519   78.441  46.326  1.00 53.95  ? 561  C   C OP1   1 
ATOM   1264  O  OP2   . C   A 1 60  ? 7.503   78.495  48.700  1.00 56.50  ? 561  C   C OP2   1 
ATOM   1265  O  "O5'" . C   A 1 60  ? 6.364   79.669  46.827  1.00 68.36  ? 561  C   C "O5'" 1 
ATOM   1266  C  "C5'" . C   A 1 60  ? 6.441   80.293  45.550  1.00 66.28  ? 561  C   C "C5'" 1 
ATOM   1267  C  "C4'" . C   A 1 60  ? 5.538   81.505  45.510  1.00 76.34  ? 561  C   C "C4'" 1 
ATOM   1268  O  "O4'" . C   A 1 60  ? 4.144   81.100  45.392  1.00 76.67  ? 561  C   C "O4'" 1 
ATOM   1269  C  "C3'" . C   A 1 60  ? 5.569   82.383  46.752  1.00 78.27  ? 561  C   C "C3'" 1 
ATOM   1270  O  "O3'" . C   A 1 60  ? 6.678   83.278  46.747  1.00 81.20  ? 561  C   C "O3'" 1 
ATOM   1271  C  "C2'" . C   A 1 60  ? 4.234   83.108  46.648  1.00 78.91  ? 561  C   C "C2'" 1 
ATOM   1272  O  "O2'" . C   A 1 60  ? 4.251   84.165  45.708  1.00 79.75  ? 561  C   C "O2'" 1 
ATOM   1273  C  "C1'" . C   A 1 60  ? 3.325   81.986  46.140  1.00 78.22  ? 561  C   C "C1'" 1 
ATOM   1274  N  N1    . C   A 1 60  ? 2.709   81.221  47.236  1.00 82.98  ? 561  C   C N1    1 
ATOM   1275  C  C2    . C   A 1 60  ? 1.989   81.909  48.211  1.00 85.07  ? 561  C   C C2    1 
ATOM   1276  O  O2    . C   A 1 60  ? 1.873   83.140  48.114  1.00 94.16  ? 561  C   C O2    1 
ATOM   1277  N  N3    . C   A 1 60  ? 1.440   81.222  49.238  1.00 81.76  ? 561  C   C N3    1 
ATOM   1278  C  C4    . C   A 1 60  ? 1.588   79.900  49.310  1.00 77.60  ? 561  C   C C4    1 
ATOM   1279  N  N4    . C   A 1 60  ? 1.040   79.267  50.349  1.00 67.67  ? 561  C   C N4    1 
ATOM   1280  C  C5    . C   A 1 60  ? 2.307   79.170  48.323  1.00 79.62  ? 561  C   C C5    1 
ATOM   1281  C  C6    . C   A 1 60  ? 2.844   79.864  47.311  1.00 85.10  ? 561  C   C C6    1 
ATOM   1282  P  P     . C   A 1 61  ? 7.273   83.812  48.143  1.00 73.30  ? 562  C   C P     1 
ATOM   1283  O  OP1   . C   A 1 61  ? 8.523   84.563  47.880  1.00 77.04  ? 562  C   C OP1   1 
ATOM   1284  O  OP2   . C   A 1 61  ? 7.285   82.671  49.085  1.00 81.29  ? 562  C   C OP2   1 
ATOM   1285  O  "O5'" . C   A 1 61  ? 6.173   84.833  48.670  1.00 86.96  ? 562  C   C "O5'" 1 
ATOM   1286  C  "C5'" . C   A 1 61  ? 5.948   86.083  48.017  1.00 85.67  ? 562  C   C "C5'" 1 
ATOM   1287  C  "C4'" . C   A 1 61  ? 5.036   86.945  48.857  1.00 86.91  ? 562  C   C "C4'" 1 
ATOM   1288  O  "O4'" . C   A 1 61  ? 3.711   86.348  48.907  1.00 81.26  ? 562  C   C "O4'" 1 
ATOM   1289  C  "C3'" . C   A 1 61  ? 5.454   87.056  50.314  1.00 87.10  ? 562  C   C "C3'" 1 
ATOM   1290  O  "O3'" . C   A 1 61  ? 6.427   88.079  50.502  1.00 88.79  ? 562  C   C "O3'" 1 
ATOM   1291  C  "C2'" . C   A 1 61  ? 4.139   87.379  51.005  1.00 82.24  ? 562  C   C "C2'" 1 
ATOM   1292  O  "O2'" . C   A 1 61  ? 3.810   88.748  50.903  1.00 83.28  ? 562  C   C "O2'" 1 
ATOM   1293  C  "C1'" . C   A 1 61  ? 3.155   86.527  50.197  1.00 78.45  ? 562  C   C "C1'" 1 
ATOM   1294  N  N1    . C   A 1 61  ? 2.942   85.199  50.784  1.00 82.31  ? 562  C   C N1    1 
ATOM   1295  C  C2    . C   A 1 61  ? 1.988   85.050  51.802  1.00 82.52  ? 562  C   C C2    1 
ATOM   1296  O  O2    . C   A 1 61  ? 1.337   86.036  52.163  1.00 86.04  ? 562  C   C O2    1 
ATOM   1297  N  N3    . C   A 1 61  ? 1.804   83.834  52.363  1.00 77.49  ? 562  C   C N3    1 
ATOM   1298  C  C4    . C   A 1 61  ? 2.528   82.793  51.945  1.00 80.21  ? 562  C   C C4    1 
ATOM   1299  N  N4    . C   A 1 61  ? 2.325   81.616  52.535  1.00 77.14  ? 562  C   C N4    1 
ATOM   1300  C  C5    . C   A 1 61  ? 3.495   82.913  50.902  1.00 81.11  ? 562  C   C C5    1 
ATOM   1301  C  C6    . C   A 1 61  ? 3.667   84.122  50.355  1.00 83.86  ? 562  C   C C6    1 
ATOM   1302  P  P     . C   A 1 62  ? 7.329   88.080  51.833  1.00 96.20  ? 563  C   C P     1 
ATOM   1303  O  OP1   . C   A 1 62  ? 8.348   89.159  51.759  1.00 94.30  ? 563  C   C OP1   1 
ATOM   1304  O  OP2   . C   A 1 62  ? 7.768   86.680  52.075  1.00 99.30  ? 563  C   C OP2   1 
ATOM   1305  O  "O5'" . C   A 1 62  ? 6.282   88.456  52.972  1.00 92.45  ? 563  C   C "O5'" 1 
ATOM   1306  C  "C5'" . C   A 1 62  ? 5.728   89.762  53.056  1.00 89.39  ? 563  C   C "C5'" 1 
ATOM   1307  C  "C4'" . C   A 1 62  ? 4.923   89.898  54.325  1.00 88.17  ? 563  C   C "C4'" 1 
ATOM   1308  O  "O4'" . C   A 1 62  ? 3.733   89.071  54.237  1.00 82.19  ? 563  C   C "O4'" 1 
ATOM   1309  C  "C3'" . C   A 1 62  ? 5.627   89.420  55.584  1.00 88.55  ? 563  C   C "C3'" 1 
ATOM   1310  O  "O3'" . C   A 1 62  ? 6.473   90.432  56.126  1.00 88.48  ? 563  C   C "O3'" 1 
ATOM   1311  C  "C2'" . C   A 1 62  ? 4.458   89.092  56.501  1.00 84.79  ? 563  C   C "C2'" 1 
ATOM   1312  O  "O2'" . C   A 1 62  ? 3.928   90.230  57.138  1.00 92.54  ? 563  C   C "O2'" 1 
ATOM   1313  C  "C1'" . C   A 1 62  ? 3.442   88.523  55.509  1.00 83.99  ? 563  C   C "C1'" 1 
ATOM   1314  N  N1    . C   A 1 62  ? 3.523   87.062  55.409  1.00 86.58  ? 563  C   C N1    1 
ATOM   1315  C  C2    . C   A 1 62  ? 2.895   86.295  56.385  1.00 87.89  ? 563  C   C C2    1 
ATOM   1316  O  O2    . C   A 1 62  ? 2.293   86.876  57.303  1.00 90.89  ? 563  C   C O2    1 
ATOM   1317  N  N3    . C   A 1 62  ? 2.961   84.942  56.310  1.00 85.70  ? 563  C   C N3    1 
ATOM   1318  C  C4    . C   A 1 62  ? 3.628   84.361  55.309  1.00 82.21  ? 563  C   C C4    1 
ATOM   1319  N  N4    . C   A 1 62  ? 3.672   83.027  55.276  1.00 69.77  ? 563  C   C N4    1 
ATOM   1320  C  C5    . C   A 1 62  ? 4.280   85.124  54.298  1.00 83.14  ? 563  C   C C5    1 
ATOM   1321  C  C6    . C   A 1 62  ? 4.201   86.459  54.385  1.00 86.38  ? 563  C   C C6    1 
ATOM   1322  P  P     . C   A 1 63  ? 7.677   90.024  57.110  1.00 89.38  ? 564  C   C P     1 
ATOM   1323  O  OP1   . C   A 1 63  ? 8.549   91.206  57.315  1.00 89.67  ? 564  C   C OP1   1 
ATOM   1324  O  OP2   . C   A 1 63  ? 8.263   88.773  56.573  1.00 86.51  ? 564  C   C OP2   1 
ATOM   1325  O  "O5'" . C   A 1 63  ? 6.947   89.688  58.488  1.00 86.19  ? 564  C   C "O5'" 1 
ATOM   1326  C  "C5'" . C   A 1 63  ? 6.149   90.663  59.149  1.00 84.29  ? 564  C   C "C5'" 1 
ATOM   1327  C  "C4'" . C   A 1 63  ? 5.290   90.011  60.207  1.00 91.36  ? 564  C   C "C4'" 1 
ATOM   1328  O  "O4'" . C   A 1 63  ? 4.348   89.095  59.583  1.00 100.61 ? 564  C   C "O4'" 1 
ATOM   1329  C  "C3'" . C   A 1 63  ? 6.018   89.132  61.206  1.00 91.64  ? 564  C   C "C3'" 1 
ATOM   1330  O  "O3'" . C   A 1 63  ? 6.617   89.901  62.230  1.00 93.50  ? 564  C   C "O3'" 1 
ATOM   1331  C  "C2'" . C   A 1 63  ? 4.888   88.263  61.740  1.00 94.79  ? 564  C   C "C2'" 1 
ATOM   1332  O  "O2'" . C   A 1 63  ? 4.070   88.929  62.683  1.00 86.81  ? 564  C   C "O2'" 1 
ATOM   1333  C  "C1'" . C   A 1 63  ? 4.092   88.002  60.460  1.00 100.69 ? 564  C   C "C1'" 1 
ATOM   1334  N  N1    . C   A 1 63  ? 4.512   86.756  59.793  1.00 104.24 ? 564  C   C N1    1 
ATOM   1335  C  C2    . C   A 1 63  ? 4.077   85.526  60.316  1.00 102.81 ? 564  C   C C2    1 
ATOM   1336  O  O2    . C   A 1 63  ? 3.324   85.524  61.305  1.00 102.00 ? 564  C   C O2    1 
ATOM   1337  N  N3    . C   A 1 63  ? 4.485   84.375  59.725  1.00 102.16 ? 564  C   C N3    1 
ATOM   1338  C  C4    . C   A 1 63  ? 5.284   84.420  58.652  1.00 100.97 ? 564  C   C C4    1 
ATOM   1339  N  N4    . C   A 1 63  ? 5.666   83.262  58.103  1.00 90.38  ? 564  C   C N4    1 
ATOM   1340  C  C5    . C   A 1 63  ? 5.728   85.657  58.093  1.00 103.28 ? 564  C   C C5    1 
ATOM   1341  C  C6    . C   A 1 63  ? 5.322   86.789  58.690  1.00 104.37 ? 564  C   C C6    1 
ATOM   1342  P  P     . C   A 1 64  ? 8.015   89.427  62.851  1.00 99.09  ? 565  C   C P     1 
ATOM   1343  O  OP1   . C   A 1 64  ? 8.568   90.528  63.680  1.00 97.27  ? 565  C   C OP1   1 
ATOM   1344  O  OP2   . C   A 1 64  ? 8.814   88.887  61.721  1.00 100.56 ? 565  C   C OP2   1 
ATOM   1345  O  "O5'" . C   A 1 64  ? 7.623   88.204  63.797  1.00 92.17  ? 565  C   C "O5'" 1 
ATOM   1346  C  "C5'" . C   A 1 64  ? 6.627   88.343  64.802  1.00 85.07  ? 565  C   C "C5'" 1 
ATOM   1347  C  "C4'" . C   A 1 64  ? 6.173   86.983  65.291  1.00 83.75  ? 565  C   C "C4'" 1 
ATOM   1348  O  "O4'" . C   A 1 64  ? 5.541   86.263  64.197  1.00 90.60  ? 565  C   C "O4'" 1 
ATOM   1349  C  "C3'" . C   A 1 64  ? 7.254   86.030  65.797  1.00 81.61  ? 565  C   C "C3'" 1 
ATOM   1350  O  "O3'" . C   A 1 64  ? 7.612   86.332  67.155  1.00 73.77  ? 565  C   C "O3'" 1 
ATOM   1351  C  "C2'" . C   A 1 64  ? 6.557   84.674  65.654  1.00 90.07  ? 565  C   C "C2'" 1 
ATOM   1352  O  "O2'" . C   A 1 64  ? 5.655   84.373  66.703  1.00 89.05  ? 565  C   C "O2'" 1 
ATOM   1353  C  "C1'" . C   A 1 64  ? 5.759   84.866  64.357  1.00 91.28  ? 565  C   C "C1'" 1 
ATOM   1354  N  N1    . C   A 1 64  ? 6.443   84.341  63.155  1.00 89.73  ? 565  C   C N1    1 
ATOM   1355  C  C2    . C   A 1 64  ? 6.438   82.959  62.933  1.00 87.03  ? 565  C   C C2    1 
ATOM   1356  O  O2    . C   A 1 64  ? 5.850   82.224  63.741  1.00 79.09  ? 565  C   C O2    1 
ATOM   1357  N  N3    . C   A 1 64  ? 7.068   82.462  61.842  1.00 84.60  ? 565  C   C N3    1 
ATOM   1358  C  C4    . C   A 1 64  ? 7.674   83.289  60.986  1.00 85.79  ? 565  C   C C4    1 
ATOM   1359  N  N4    . C   A 1 64  ? 8.264   82.754  59.913  1.00 77.02  ? 565  C   C N4    1 
ATOM   1360  C  C5    . C   A 1 64  ? 7.696   84.701  61.189  1.00 84.71  ? 565  C   C C5    1 
ATOM   1361  C  C6    . C   A 1 64  ? 7.073   85.179  62.274  1.00 87.59  ? 565  C   C C6    1 
ATOM   1362  P  P     . U   A 1 65  ? 9.087   85.965  67.722  1.00 74.62  ? 566  U   C P     1 
ATOM   1363  O  OP1   . U   A 1 65  ? 9.164   86.264  69.183  1.00 76.88  ? 566  U   C OP1   1 
ATOM   1364  O  OP2   . U   A 1 65  ? 10.153  86.483  66.823  1.00 76.69  ? 566  U   C OP2   1 
ATOM   1365  O  "O5'" . U   A 1 65  ? 9.108   84.388  67.636  1.00 75.04  ? 566  U   C "O5'" 1 
ATOM   1366  C  "C5'" . U   A 1 65  ? 8.291   83.633  68.502  1.00 79.09  ? 566  U   C "C5'" 1 
ATOM   1367  C  "C4'" . U   A 1 65  ? 8.398   82.178  68.162  1.00 83.20  ? 566  U   C "C4'" 1 
ATOM   1368  O  "O4'" . U   A 1 65  ? 7.915   81.969  66.808  1.00 88.28  ? 566  U   C "O4'" 1 
ATOM   1369  C  "C3'" . U   A 1 65  ? 9.813   81.634  68.122  1.00 82.51  ? 566  U   C "C3'" 1 
ATOM   1370  O  "O3'" . U   A 1 65  ? 10.263  81.317  69.431  1.00 83.76  ? 566  U   C "O3'" 1 
ATOM   1371  C  "C2'" . U   A 1 65  ? 9.626   80.398  67.254  1.00 83.39  ? 566  U   C "C2'" 1 
ATOM   1372  O  "O2'" . U   A 1 65  ? 8.990   79.350  67.952  1.00 83.81  ? 566  U   C "O2'" 1 
ATOM   1373  C  "C1'" . U   A 1 65  ? 8.658   80.926  66.194  1.00 81.99  ? 566  U   C "C1'" 1 
ATOM   1374  N  N1    . U   A 1 65  ? 9.347   81.474  65.016  1.00 75.75  ? 566  U   C N1    1 
ATOM   1375  C  C2    . U   A 1 65  ? 9.656   80.599  63.984  1.00 78.26  ? 566  U   C C2    1 
ATOM   1376  O  O2    . U   A 1 65  ? 9.375   79.410  64.009  1.00 71.83  ? 566  U   C O2    1 
ATOM   1377  N  N3    . U   A 1 65  ? 10.312  81.169  62.921  1.00 79.51  ? 566  U   C N3    1 
ATOM   1378  C  C4    . U   A 1 65  ? 10.688  82.489  62.791  1.00 82.02  ? 566  U   C C4    1 
ATOM   1379  O  O4    . U   A 1 65  ? 11.304  82.848  61.786  1.00 81.25  ? 566  U   C O4    1 
ATOM   1380  C  C5    . U   A 1 65  ? 10.328  83.325  63.898  1.00 80.27  ? 566  U   C C5    1 
ATOM   1381  C  C6    . U   A 1 65  ? 9.684   82.801  64.942  1.00 71.82  ? 566  U   C C6    1 
ATOM   1382  P  P     . G   A 1 66  ? 11.831  81.318  69.748  1.00 85.61  ? 567  G   C P     1 
ATOM   1383  O  OP1   . G   A 1 66  ? 12.025  80.909  71.163  1.00 82.74  ? 567  G   C OP1   1 
ATOM   1384  O  OP2   . G   A 1 66  ? 12.383  82.614  69.269  1.00 85.39  ? 567  G   C OP2   1 
ATOM   1385  O  "O5'" . G   A 1 66  ? 12.381  80.153  68.817  1.00 87.83  ? 567  G   C "O5'" 1 
ATOM   1386  C  "C5'" . G   A 1 66  ? 11.894  78.824  68.961  1.00 79.93  ? 567  G   C "C5'" 1 
ATOM   1387  C  "C4'" . G   A 1 66  ? 12.417  77.941  67.850  1.00 79.20  ? 567  G   C "C4'" 1 
ATOM   1388  O  "O4'" . G   A 1 66  ? 11.800  78.288  66.579  1.00 75.41  ? 567  G   C "O4'" 1 
ATOM   1389  C  "C3'" . G   A 1 66  ? 13.898  78.059  67.543  1.00 73.96  ? 567  G   C "C3'" 1 
ATOM   1390  O  "O3'" . G   A 1 66  ? 14.700  77.393  68.499  1.00 71.17  ? 567  G   C "O3'" 1 
ATOM   1391  C  "C2'" . G   A 1 66  ? 13.961  77.420  66.166  1.00 77.97  ? 567  G   C "C2'" 1 
ATOM   1392  O  "O2'" . G   A 1 66  ? 13.794  76.013  66.212  1.00 71.02  ? 567  G   C "O2'" 1 
ATOM   1393  C  "C1'" . G   A 1 66  ? 12.721  78.039  65.521  1.00 79.81  ? 567  G   C "C1'" 1 
ATOM   1394  N  N9    . G   A 1 66  ? 13.023  79.309  64.863  1.00 84.06  ? 567  G   C N9    1 
ATOM   1395  C  C8    . G   A 1 66  ? 12.722  80.569  65.319  1.00 84.49  ? 567  G   C C8    1 
ATOM   1396  N  N7    . G   A 1 66  ? 13.121  81.517  64.513  1.00 87.16  ? 567  G   C N7    1 
ATOM   1397  C  C5    . G   A 1 66  ? 13.723  80.843  63.460  1.00 85.28  ? 567  G   C C5    1 
ATOM   1398  C  C6    . G   A 1 66  ? 14.346  81.343  62.280  1.00 86.00  ? 567  G   C C6    1 
ATOM   1399  O  O6    . G   A 1 66  ? 14.491  82.526  61.923  1.00 73.32  ? 567  G   C O6    1 
ATOM   1400  N  N1    . G   A 1 66  ? 14.828  80.306  61.479  1.00 80.05  ? 567  G   C N1    1 
ATOM   1401  C  C2    . G   A 1 66  ? 14.725  78.969  61.774  1.00 77.57  ? 567  G   C C2    1 
ATOM   1402  N  N2    . G   A 1 66  ? 15.246  78.129  60.882  1.00 72.62  ? 567  G   C N2    1 
ATOM   1403  N  N3    . G   A 1 66  ? 14.151  78.493  62.867  1.00 84.36  ? 567  G   C N3    1 
ATOM   1404  C  C4    . G   A 1 66  ? 13.674  79.478  63.660  1.00 85.48  ? 567  G   C C4    1 
ATOM   1405  P  P     . G   A 1 67  ? 16.156  77.963  68.811  1.00 65.47  ? 568  G   C P     1 
ATOM   1406  O  OP1   . G   A 1 67  ? 16.719  77.231  69.978  1.00 66.35  ? 568  G   C OP1   1 
ATOM   1407  O  OP2   . G   A 1 67  ? 16.043  79.445  68.851  1.00 65.99  ? 568  G   C OP2   1 
ATOM   1408  O  "O5'" . G   A 1 67  ? 16.963  77.561  67.499  1.00 69.11  ? 568  G   C "O5'" 1 
ATOM   1409  C  "C5'" . G   A 1 67  ? 17.106  76.190  67.144  1.00 61.38  ? 568  G   C "C5'" 1 
ATOM   1410  C  "C4'" . G   A 1 67  ? 17.783  76.054  65.803  1.00 66.23  ? 568  G   C "C4'" 1 
ATOM   1411  O  "O4'" . G   A 1 67  ? 16.921  76.586  64.762  1.00 56.51  ? 568  G   C "O4'" 1 
ATOM   1412  C  "C3'" . G   A 1 67  ? 19.082  76.822  65.602  1.00 64.55  ? 568  G   C "C3'" 1 
ATOM   1413  O  "O3'" . G   A 1 67  ? 20.194  76.169  66.186  1.00 55.60  ? 568  G   C "O3'" 1 
ATOM   1414  C  "C2'" . G   A 1 67  ? 19.183  76.816  64.089  1.00 62.90  ? 568  G   C "C2'" 1 
ATOM   1415  O  "O2'" . G   A 1 67  ? 19.560  75.539  63.609  1.00 62.34  ? 568  G   C "O2'" 1 
ATOM   1416  C  "C1'" . G   A 1 67  ? 17.728  77.105  63.709  1.00 65.34  ? 568  G   C "C1'" 1 
ATOM   1417  N  N9    . G   A 1 67  ? 17.483  78.540  63.591  1.00 60.24  ? 568  G   C N9    1 
ATOM   1418  C  C8    . G   A 1 67  ? 16.825  79.352  64.485  1.00 58.70  ? 568  G   C C8    1 
ATOM   1419  N  N7    . G   A 1 67  ? 16.806  80.604  64.118  1.00 57.75  ? 568  G   C N7    1 
ATOM   1420  C  C5    . G   A 1 67  ? 17.487  80.616  62.906  1.00 60.50  ? 568  G   C C5    1 
ATOM   1421  C  C6    . G   A 1 67  ? 17.805  81.694  62.038  1.00 55.64  ? 568  G   C C6    1 
ATOM   1422  O  O6    . G   A 1 67  ? 17.554  82.891  62.181  1.00 62.68  ? 568  G   C O6    1 
ATOM   1423  N  N1    . G   A 1 67  ? 18.498  81.261  60.913  1.00 47.22  ? 568  G   C N1    1 
ATOM   1424  C  C2    . G   A 1 67  ? 18.851  79.959  60.658  1.00 51.69  ? 568  G   C C2    1 
ATOM   1425  N  N2    . G   A 1 67  ? 19.514  79.740  59.518  1.00 47.83  ? 568  G   C N2    1 
ATOM   1426  N  N3    . G   A 1 67  ? 18.573  78.948  61.464  1.00 53.55  ? 568  G   C N3    1 
ATOM   1427  C  C4    . G   A 1 67  ? 17.895  79.347  62.561  1.00 57.55  ? 568  G   C C4    1 
ATOM   1428  P  P     . G   A 1 68  ? 21.418  77.043  66.741  1.00 56.60  ? 569  G   C P     1 
ATOM   1429  O  OP1   . G   A 1 68  ? 22.281  76.123  67.538  1.00 58.16  ? 569  G   C OP1   1 
ATOM   1430  O  OP2   . G   A 1 68  ? 20.816  78.232  67.387  1.00 60.12  ? 569  G   C OP2   1 
ATOM   1431  O  "O5'" . G   A 1 68  ? 22.209  77.495  65.430  1.00 46.90  ? 569  G   C "O5'" 1 
ATOM   1432  C  "C5'" . G   A 1 68  ? 22.595  76.523  64.463  1.00 40.73  ? 569  G   C "C5'" 1 
ATOM   1433  C  "C4'" . G   A 1 68  ? 22.975  77.174  63.157  1.00 42.80  ? 569  G   C "C4'" 1 
ATOM   1434  O  "O4'" . G   A 1 68  ? 21.808  77.778  62.539  1.00 51.46  ? 569  G   C "O4'" 1 
ATOM   1435  C  "C3'" . G   A 1 68  ? 23.988  78.308  63.233  1.00 45.50  ? 569  G   C "C3'" 1 
ATOM   1436  O  "O3'" . G   A 1 68  ? 25.320  77.825  63.279  1.00 30.74  ? 569  G   C "O3'" 1 
ATOM   1437  C  "C2'" . G   A 1 68  ? 23.734  79.050  61.930  1.00 40.23  ? 569  G   C "C2'" 1 
ATOM   1438  O  "O2'" . G   A 1 68  ? 24.348  78.436  60.828  1.00 47.35  ? 569  G   C "O2'" 1 
ATOM   1439  C  "C1'" . G   A 1 68  ? 22.213  78.924  61.797  1.00 52.73  ? 569  G   C "C1'" 1 
ATOM   1440  N  N9    . G   A 1 68  ? 21.549  80.094  62.354  1.00 51.86  ? 569  G   C N9    1 
ATOM   1441  C  C8    . G   A 1 68  ? 20.761  80.150  63.478  1.00 51.61  ? 569  G   C C8    1 
ATOM   1442  N  N7    . G   A 1 68  ? 20.317  81.350  63.731  1.00 53.20  ? 569  G   C N7    1 
ATOM   1443  C  C5    . G   A 1 68  ? 20.840  82.135  62.709  1.00 61.43  ? 569  G   C C5    1 
ATOM   1444  C  C6    . G   A 1 68  ? 20.693  83.530  62.442  1.00 62.50  ? 569  G   C C6    1 
ATOM   1445  O  O6    . G   A 1 68  ? 20.061  84.378  63.089  1.00 57.32  ? 569  G   C O6    1 
ATOM   1446  N  N1    . G   A 1 68  ? 21.385  83.904  61.286  1.00 65.16  ? 569  G   C N1    1 
ATOM   1447  C  C2    . G   A 1 68  ? 22.126  83.051  60.492  1.00 59.00  ? 569  G   C C2    1 
ATOM   1448  N  N2    . G   A 1 68  ? 22.722  83.601  59.419  1.00 53.07  ? 569  G   C N2    1 
ATOM   1449  N  N3    . G   A 1 68  ? 22.270  81.757  60.735  1.00 55.22  ? 569  G   C N3    1 
ATOM   1450  C  C4    . G   A 1 68  ? 21.604  81.371  61.849  1.00 58.08  ? 569  G   C C4    1 
ATOM   1451  P  P     . G   A 1 69  ? 26.469  78.742  63.907  1.00 42.06  ? 570  G   C P     1 
ATOM   1452  O  OP1   . G   A 1 69  ? 27.706  77.916  64.089  1.00 49.62  ? 570  G   C OP1   1 
ATOM   1453  O  OP2   . G   A 1 69  ? 25.863  79.417  65.089  1.00 55.16  ? 570  G   C OP2   1 
ATOM   1454  O  "O5'" . G   A 1 69  ? 26.741  79.850  62.792  1.00 44.61  ? 570  G   C "O5'" 1 
ATOM   1455  C  "C5'" . G   A 1 69  ? 27.092  79.485  61.463  1.00 33.20  ? 570  G   C "C5'" 1 
ATOM   1456  C  "C4'" . G   A 1 69  ? 27.130  80.705  60.590  1.00 40.74  ? 570  G   C "C4'" 1 
ATOM   1457  O  "O4'" . G   A 1 69  ? 25.784  81.249  60.491  1.00 48.03  ? 570  G   C "O4'" 1 
ATOM   1458  C  "C3'" . G   A 1 69  ? 27.964  81.878  61.095  1.00 35.56  ? 570  G   C "C3'" 1 
ATOM   1459  O  "O3'" . G   A 1 69  ? 29.332  81.726  60.732  1.00 41.10  ? 570  G   C "O3'" 1 
ATOM   1460  C  "C2'" . G   A 1 69  ? 27.340  83.041  60.334  1.00 32.36  ? 570  G   C "C2'" 1 
ATOM   1461  O  "O2'" . G   A 1 69  ? 27.740  83.051  58.991  1.00 44.05  ? 570  G   C "O2'" 1 
ATOM   1462  C  "C1'" . G   A 1 69  ? 25.860  82.660  60.337  1.00 48.04  ? 570  G   C "C1'" 1 
ATOM   1463  N  N9    . G   A 1 69  ? 25.116  83.289  61.424  1.00 56.16  ? 570  G   C N9    1 
ATOM   1464  C  C8    . G   A 1 69  ? 24.617  82.672  62.546  1.00 59.23  ? 570  G   C C8    1 
ATOM   1465  N  N7    . G   A 1 69  ? 23.998  83.492  63.350  1.00 55.00  ? 570  G   C N7    1 
ATOM   1466  C  C5    . G   A 1 69  ? 24.092  84.726  62.719  1.00 63.52  ? 570  G   C C5    1 
ATOM   1467  C  C6    . G   A 1 69  ? 23.592  85.998  63.111  1.00 63.70  ? 570  G   C C6    1 
ATOM   1468  O  O6    . G   A 1 69  ? 22.943  86.289  64.130  1.00 57.23  ? 570  G   C O6    1 
ATOM   1469  N  N1    . G   A 1 69  ? 23.910  86.982  62.175  1.00 56.87  ? 570  G   C N1    1 
ATOM   1470  C  C2    . G   A 1 69  ? 24.608  86.768  61.010  1.00 54.93  ? 570  G   C C2    1 
ATOM   1471  N  N2    . G   A 1 69  ? 24.818  87.846  60.244  1.00 48.27  ? 570  G   C N2    1 
ATOM   1472  N  N3    . G   A 1 69  ? 25.070  85.584  60.630  1.00 55.57  ? 570  G   C N3    1 
ATOM   1473  C  C4    . G   A 1 69  ? 24.780  84.618  61.528  1.00 51.47  ? 570  G   C C4    1 
ATOM   1474  P  P     . U   A 1 70  ? 30.490  82.418  61.622  1.00 51.79  ? 571  U   C P     1 
ATOM   1475  O  OP1   . U   A 1 70  ? 31.819  82.016  61.092  1.00 53.39  ? 571  U   C OP1   1 
ATOM   1476  O  OP2   . U   A 1 70  ? 30.142  82.113  63.041  1.00 52.57  ? 571  U   C OP2   1 
ATOM   1477  O  "O5'" . U   A 1 70  ? 30.356  83.984  61.376  1.00 38.64  ? 571  U   C "O5'" 1 
ATOM   1478  C  "C5'" . U   A 1 70  ? 30.415  84.534  60.072  1.00 49.38  ? 571  U   C "C5'" 1 
ATOM   1479  C  "C4'" . U   A 1 70  ? 29.960  85.980  60.103  1.00 52.72  ? 571  U   C "C4'" 1 
ATOM   1480  O  "O4'" . U   A 1 70  ? 28.535  86.067  60.392  1.00 53.06  ? 571  U   C "O4'" 1 
ATOM   1481  C  "C3'" . U   A 1 70  ? 30.617  86.806  61.188  1.00 46.36  ? 571  U   C "C3'" 1 
ATOM   1482  O  "O3'" . U   A 1 70  ? 31.868  87.290  60.736  1.00 50.90  ? 571  U   C "O3'" 1 
ATOM   1483  C  "C2'" . U   A 1 70  ? 29.607  87.921  61.433  1.00 43.09  ? 571  U   C "C2'" 1 
ATOM   1484  O  "O2'" . U   A 1 70  ? 29.710  88.978  60.512  1.00 57.14  ? 571  U   C "O2'" 1 
ATOM   1485  C  "C1'" . U   A 1 70  ? 28.283  87.192  61.224  1.00 48.66  ? 571  U   C "C1'" 1 
ATOM   1486  N  N1    . U   A 1 70  ? 27.657  86.733  62.476  1.00 54.51  ? 571  U   C N1    1 
ATOM   1487  C  C2    . U   A 1 70  ? 27.024  87.680  63.269  1.00 48.60  ? 571  U   C C2    1 
ATOM   1488  O  O2    . U   A 1 70  ? 27.012  88.871  63.001  1.00 44.54  ? 571  U   C O2    1 
ATOM   1489  N  N3    . U   A 1 70  ? 26.424  87.178  64.394  1.00 40.47  ? 571  U   C N3    1 
ATOM   1490  C  C4    . U   A 1 70  ? 26.415  85.864  64.813  1.00 45.98  ? 571  U   C C4    1 
ATOM   1491  O  O4    . U   A 1 70  ? 25.806  85.558  65.837  1.00 41.16  ? 571  U   C O4    1 
ATOM   1492  C  C5    . U   A 1 70  ? 27.111  84.959  63.957  1.00 46.91  ? 571  U   C C5    1 
ATOM   1493  C  C6    . U   A 1 70  ? 27.688  85.410  62.846  1.00 46.96  ? 571  U   C C6    1 
ATOM   1494  P  P     . C   A 1 71  ? 32.844  88.033  61.768  1.00 63.97  ? 572  C   C P     1 
ATOM   1495  O  OP1   . C   A 1 71  ? 34.208  88.088  61.185  1.00 71.44  ? 572  C   C OP1   1 
ATOM   1496  O  OP2   . C   A 1 71  ? 32.646  87.411  63.104  1.00 58.32  ? 572  C   C OP2   1 
ATOM   1497  O  "O5'" . C   A 1 71  ? 32.284  89.527  61.784  1.00 63.99  ? 572  C   C "O5'" 1 
ATOM   1498  C  "C5'" . C   A 1 71  ? 32.932  90.530  62.539  1.00 64.78  ? 572  C   C "C5'" 1 
ATOM   1499  C  "C4'" . C   A 1 71  ? 31.941  91.575  62.960  1.00 64.33  ? 572  C   C "C4'" 1 
ATOM   1500  O  "O4'" . C   A 1 71  ? 30.600  91.021  62.953  1.00 55.92  ? 572  C   C "O4'" 1 
ATOM   1501  C  "C3'" . C   A 1 71  ? 32.129  92.035  64.388  1.00 68.78  ? 572  C   C "C3'" 1 
ATOM   1502  O  "O3'" . C   A 1 71  ? 33.167  92.996  64.467  1.00 87.55  ? 572  C   C "O3'" 1 
ATOM   1503  C  "C2'" . C   A 1 71  ? 30.761  92.612  64.706  1.00 63.56  ? 572  C   C "C2'" 1 
ATOM   1504  O  "O2'" . C   A 1 71  ? 30.601  93.893  64.132  1.00 63.78  ? 572  C   C "O2'" 1 
ATOM   1505  C  "C1'" . C   A 1 71  ? 29.849  91.604  64.003  1.00 50.58  ? 572  C   C "C1'" 1 
ATOM   1506  N  N1    . C   A 1 71  ? 29.355  90.527  64.883  1.00 46.26  ? 572  C   C N1    1 
ATOM   1507  C  C2    . C   A 1 71  ? 28.272  90.798  65.721  1.00 35.55  ? 572  C   C C2    1 
ATOM   1508  O  O2    . C   A 1 71  ? 27.797  91.952  65.743  1.00 41.33  ? 572  C   C O2    1 
ATOM   1509  N  N3    . C   A 1 71  ? 27.770  89.815  66.495  1.00 35.17  ? 572  C   C N3    1 
ATOM   1510  C  C4    . C   A 1 71  ? 28.312  88.607  66.474  1.00 36.67  ? 572  C   C C4    1 
ATOM   1511  N  N4    . C   A 1 71  ? 27.758  87.675  67.249  1.00 39.35  ? 572  C   C N4    1 
ATOM   1512  C  C5    . C   A 1 71  ? 29.440  88.299  65.650  1.00 37.59  ? 572  C   C C5    1 
ATOM   1513  C  C6    . C   A 1 71  ? 29.925  89.282  64.876  1.00 38.52  ? 572  C   C C6    1 
ATOM   1514  P  P     . A   A 1 72  ? 34.381  92.766  65.500  1.00 92.75  ? 573  A   C P     1 
ATOM   1515  O  OP1   . A   A 1 72  ? 34.709  91.316  65.571  1.00 68.44  ? 573  A   C OP1   1 
ATOM   1516  O  OP2   . A   A 1 72  ? 34.032  93.514  66.745  1.00 93.95  ? 573  A   C OP2   1 
ATOM   1517  O  "O5'" . A   A 1 72  ? 35.596  93.539  64.823  1.00 92.14  ? 573  A   C "O5'" 1 
ATOM   1518  C  "C5'" . A   A 1 72  ? 36.499  92.886  63.945  1.00 78.31  ? 573  A   C "C5'" 1 
ATOM   1519  C  "C4'" . A   A 1 72  ? 37.904  93.088  64.441  1.00 78.80  ? 573  A   C "C4'" 1 
ATOM   1520  O  "O4'" . A   A 1 72  ? 38.242  91.989  65.332  1.00 77.46  ? 573  A   C "O4'" 1 
ATOM   1521  C  "C3'" . A   A 1 72  ? 38.945  93.051  63.341  1.00 78.56  ? 573  A   C "C3'" 1 
ATOM   1522  O  "O3'" . A   A 1 72  ? 39.672  94.257  63.096  1.00 75.87  ? 573  A   C "O3'" 1 
ATOM   1523  C  "C2'" . A   A 1 72  ? 39.543  91.646  63.330  1.00 73.76  ? 573  A   C "C2'" 1 
ATOM   1524  O  "O2'" . A   A 1 72  ? 40.950  91.666  63.240  1.00 95.67  ? 573  A   C "O2'" 1 
ATOM   1525  C  "C1'" . A   A 1 72  ? 39.197  91.133  64.729  1.00 73.99  ? 573  A   C "C1'" 1 
ATOM   1526  N  N9    . A   A 1 72  ? 38.709  89.750  64.789  1.00 62.07  ? 573  A   C N9    1 
ATOM   1527  C  C8    . A   A 1 72  ? 37.417  89.288  64.708  1.00 56.27  ? 573  A   C C8    1 
ATOM   1528  N  N7    . A   A 1 72  ? 37.316  87.985  64.814  1.00 58.44  ? 573  A   C N7    1 
ATOM   1529  C  C5    . A   A 1 72  ? 38.630  87.557  64.971  1.00 52.70  ? 573  A   C C5    1 
ATOM   1530  C  C6    . A   A 1 72  ? 39.206  86.272  65.113  1.00 56.62  ? 573  A   C C6    1 
ATOM   1531  N  N6    . A   A 1 72  ? 38.502  85.136  65.122  1.00 57.39  ? 573  A   C N6    1 
ATOM   1532  N  N1    . A   A 1 72  ? 40.548  86.194  65.234  1.00 55.91  ? 573  A   C N1    1 
ATOM   1533  C  C2    . A   A 1 72  ? 41.258  87.329  65.200  1.00 57.58  ? 573  A   C C2    1 
ATOM   1534  N  N3    . A   A 1 72  ? 40.836  88.588  65.060  1.00 48.86  ? 573  A   C N3    1 
ATOM   1535  C  C4    . A   A 1 72  ? 39.497  88.632  64.951  1.00 53.73  ? 573  A   C C4    1 
ATOM   1536  P  P     . C   A 1 73  ? 40.688  94.815  64.211  1.00 74.56  ? 574  C   C P     1 
ATOM   1537  O  OP1   . C   A 1 73  ? 40.661  93.907  65.390  1.00 76.05  ? 574  C   C OP1   1 
ATOM   1538  O  OP2   . C   A 1 73  ? 40.360  96.250  64.385  1.00 81.82  ? 574  C   C OP2   1 
ATOM   1539  O  "O5'" . C   A 1 73  ? 42.120  94.716  63.523  1.00 75.83  ? 574  C   C "O5'" 1 
ATOM   1540  C  "C5'" . C   A 1 73  ? 42.221  94.558  62.122  1.00 58.77  ? 574  C   C "C5'" 1 
ATOM   1541  C  "C4'" . C   A 1 73  ? 43.514  93.893  61.758  1.00 49.23  ? 574  C   C "C4'" 1 
ATOM   1542  O  "O4'" . C   A 1 73  ? 44.554  94.905  61.676  1.00 50.62  ? 574  C   C "O4'" 1 
ATOM   1543  C  "C3'" . C   A 1 73  ? 43.961  92.959  62.876  1.00 50.75  ? 574  C   C "C3'" 1 
ATOM   1544  O  "O3'" . C   A 1 73  ? 43.935  91.560  62.659  1.00 73.54  ? 574  C   C "O3'" 1 
ATOM   1545  C  "C2'" . C   A 1 73  ? 45.017  93.690  63.688  1.00 49.53  ? 574  C   C "C2'" 1 
ATOM   1546  O  "O2'" . C   A 1 73  ? 46.124  92.955  64.157  1.00 38.76  ? 574  C   C "O2'" 1 
ATOM   1547  C  "C1'" . C   A 1 73  ? 45.534  94.683  62.662  1.00 38.90  ? 574  C   C "C1'" 1 
ATOM   1548  N  N1    . C   A 1 73  ? 45.992  95.935  63.239  1.00 36.23  ? 574  C   C N1    1 
ATOM   1549  C  C2    . C   A 1 73  ? 47.276  96.342  62.929  1.00 31.41  ? 574  C   C C2    1 
ATOM   1550  O  O2    . C   A 1 73  ? 47.887  95.742  62.035  1.00 25.25  ? 574  C   C O2    1 
ATOM   1551  N  N3    . C   A 1 73  ? 47.816  97.387  63.582  1.00 34.78  ? 574  C   C N3    1 
ATOM   1552  C  C4    . C   A 1 73  ? 47.092  98.055  64.477  1.00 34.48  ? 574  C   C C4    1 
ATOM   1553  N  N4    . C   A 1 73  ? 47.689  99.061  65.124  1.00 36.04  ? 574  C   C N4    1 
ATOM   1554  C  C5    . C   A 1 73  ? 45.731  97.715  64.752  1.00 29.28  ? 574  C   C C5    1 
ATOM   1555  C  C6    . C   A 1 73  ? 45.224  96.655  64.114  1.00 32.05  ? 574  C   C C6    1 
ATOM   1556  P  P     . C   A 1 74  ? 45.300  90.740  62.458  1.00 60.53  ? 575  C   C P     1 
ATOM   1557  O  OP1   . C   A 1 74  ? 45.934  90.398  63.755  1.00 68.06  ? 575  C   C OP1   1 
ATOM   1558  O  OP2   . C   A 1 74  ? 46.082  91.427  61.405  1.00 80.56  ? 575  C   C OP2   1 
ATOM   1559  O  "O5'" . C   A 1 74  ? 44.724  89.411  61.861  1.00 59.69  ? 575  C   C "O5'" 1 
ATOM   1560  C  "C5'" . C   A 1 74  ? 43.457  88.974  62.274  1.00 50.27  ? 575  C   C "C5'" 1 
ATOM   1561  C  "C4'" . C   A 1 74  ? 43.245  87.603  61.760  1.00 56.63  ? 575  C   C "C4'" 1 
ATOM   1562  O  "O4'" . C   A 1 74  ? 42.231  86.920  62.511  1.00 46.03  ? 575  C   C "O4'" 1 
ATOM   1563  C  "C3'" . C   A 1 74  ? 42.809  87.476  60.314  1.00 57.50  ? 575  C   C "C3'" 1 
ATOM   1564  O  "O3'" . C   A 1 74  ? 43.927  87.805  59.459  1.00 63.35  ? 575  C   C "O3'" 1 
ATOM   1565  C  "C2'" . C   A 1 74  ? 42.350  86.018  60.314  1.00 52.05  ? 575  C   C "C2'" 1 
ATOM   1566  O  "O2'" . C   A 1 74  ? 43.419  85.094  60.283  1.00 49.68  ? 575  C   C "O2'" 1 
ATOM   1567  C  "C1'" . C   A 1 74  ? 41.691  85.904  61.699  1.00 58.74  ? 575  C   C "C1'" 1 
ATOM   1568  N  N1    . C   A 1 74  ? 40.241  86.076  61.679  1.00 60.83  ? 575  C   C N1    1 
ATOM   1569  C  C2    . C   A 1 74  ? 39.446  84.944  61.817  1.00 60.84  ? 575  C   C C2    1 
ATOM   1570  O  O2    . C   A 1 74  ? 40.005  83.841  61.971  1.00 62.22  ? 575  C   C O2    1 
ATOM   1571  N  N3    . C   A 1 74  ? 38.103  85.073  61.780  1.00 60.49  ? 575  C   C N3    1 
ATOM   1572  C  C4    . C   A 1 74  ? 37.556  86.279  61.606  1.00 63.59  ? 575  C   C C4    1 
ATOM   1573  N  N4    . C   A 1 74  ? 36.226  86.362  61.564  1.00 62.39  ? 575  C   C N4    1 
ATOM   1574  C  C5    . C   A 1 74  ? 38.352  87.458  61.468  1.00 61.11  ? 575  C   C C5    1 
ATOM   1575  C  C6    . C   A 1 74  ? 39.677  87.311  61.515  1.00 53.00  ? 575  C   C C6    1 
ATOM   1576  P  P     . A   A 1 75  ? 43.797  87.717  57.849  1.00 51.80  ? 576  A   C P     1 
ATOM   1577  O  OP1   . A   A 1 75  ? 45.043  88.256  57.224  1.00 45.70  ? 576  A   C OP1   1 
ATOM   1578  O  OP2   . A   A 1 75  ? 42.487  88.295  57.471  1.00 45.01  ? 576  A   C OP2   1 
ATOM   1579  O  "O5'" . A   A 1 75  ? 43.837  86.137  57.633  1.00 53.44  ? 576  A   C "O5'" 1 
ATOM   1580  C  "C5'" . A   A 1 75  ? 43.549  85.557  56.396  1.00 47.72  ? 576  A   C "C5'" 1 
ATOM   1581  C  "C4'" . A   A 1 75  ? 42.753  84.294  56.588  1.00 44.66  ? 576  A   C "C4'" 1 
ATOM   1582  O  "O4'" . A   A 1 75  ? 42.026  84.307  57.849  1.00 53.82  ? 576  A   C "O4'" 1 
ATOM   1583  C  "C3'" . A   A 1 75  ? 41.683  84.190  55.522  1.00 48.68  ? 576  A   C "C3'" 1 
ATOM   1584  O  "O3'" . A   A 1 75  ? 42.381  83.849  54.328  1.00 34.63  ? 576  A   C "O3'" 1 
ATOM   1585  C  "C2'" . A   A 1 75  ? 40.610  83.342  56.199  1.00 43.53  ? 576  A   C "C2'" 1 
ATOM   1586  O  "O2'" . A   A 1 75  ? 40.867  81.957  56.139  1.00 48.92  ? 576  A   C "O2'" 1 
ATOM   1587  C  "C1'" . A   A 1 75  ? 40.687  83.855  57.646  1.00 46.86  ? 576  A   C "C1'" 1 
ATOM   1588  N  N9    . A   A 1 75  ? 39.770  84.977  57.884  1.00 48.73  ? 576  A   C N9    1 
ATOM   1589  C  C8    . A   A 1 75  ? 40.040  86.321  57.783  1.00 47.94  ? 576  A   C C8    1 
ATOM   1590  N  N7    . A   A 1 75  ? 38.992  87.090  57.965  1.00 50.66  ? 576  A   C N7    1 
ATOM   1591  C  C5    . A   A 1 75  ? 37.961  86.194  58.210  1.00 54.44  ? 576  A   C C5    1 
ATOM   1592  C  C6    . A   A 1 75  ? 36.572  86.373  58.415  1.00 61.79  ? 576  A   C C6    1 
ATOM   1593  N  N6    . A   A 1 75  ? 35.967  87.560  58.375  1.00 54.47  ? 576  A   C N6    1 
ATOM   1594  N  N1    . A   A 1 75  ? 35.820  85.269  58.638  1.00 60.94  ? 576  A   C N1    1 
ATOM   1595  C  C2    . A   A 1 75  ? 36.422  84.074  58.627  1.00 59.15  ? 576  A   C C2    1 
ATOM   1596  N  N3    . A   A 1 75  ? 37.710  83.775  58.415  1.00 62.58  ? 576  A   C N3    1 
ATOM   1597  C  C4    . A   A 1 75  ? 38.433  84.891  58.205  1.00 54.73  ? 576  A   C C4    1 
ATOM   1598  O  OP3   . G   B 1 1   ? 79.550  87.201  135.668 1.00 69.04  ? 501  G   D OP3   1 
ATOM   1599  P  P     . G   B 1 1   ? 78.734  87.708  134.484 1.00 62.79  ? 501  G   D P     1 
ATOM   1600  O  OP1   . G   B 1 1   ? 77.247  87.638  134.732 1.00 54.73  ? 501  G   D OP1   1 
ATOM   1601  O  OP2   . G   B 1 1   ? 79.146  87.006  133.202 1.00 52.20  ? 501  G   D OP2   1 
ATOM   1602  O  "O5'" . G   B 1 1   ? 79.084  89.301  134.304 1.00 55.99  ? 501  G   D "O5'" 1 
ATOM   1603  C  "C5'" . G   B 1 1   ? 78.630  90.287  135.248 1.00 36.93  ? 501  G   D "C5'" 1 
ATOM   1604  C  "C4'" . G   B 1 1   ? 79.182  91.636  134.873 1.00 48.56  ? 501  G   D "C4'" 1 
ATOM   1605  O  "O4'" . G   B 1 1   ? 80.600  91.668  135.165 1.00 55.08  ? 501  G   D "O4'" 1 
ATOM   1606  C  "C3'" . G   B 1 1   ? 79.065  91.951  133.390 1.00 46.87  ? 501  G   D "C3'" 1 
ATOM   1607  O  "O3'" . G   B 1 1   ? 77.813  92.580  133.128 1.00 48.71  ? 501  G   D "O3'" 1 
ATOM   1608  C  "C2'" . G   B 1 1   ? 80.255  92.871  133.155 1.00 56.86  ? 501  G   D "C2'" 1 
ATOM   1609  O  "O2'" . G   B 1 1   ? 80.032  94.214  133.542 1.00 53.47  ? 501  G   D "O2'" 1 
ATOM   1610  C  "C1'" . G   B 1 1   ? 81.299  92.231  134.069 1.00 58.86  ? 501  G   D "C1'" 1 
ATOM   1611  N  N9    . G   B 1 1   ? 82.046  91.155  133.425 1.00 49.98  ? 501  G   D N9    1 
ATOM   1612  C  C8    . G   B 1 1   ? 81.930  89.809  133.677 1.00 43.70  ? 501  G   D C8    1 
ATOM   1613  N  N7    . G   B 1 1   ? 82.761  89.085  132.980 1.00 47.18  ? 501  G   D N7    1 
ATOM   1614  C  C5    . G   B 1 1   ? 83.463  90.005  132.213 1.00 46.88  ? 501  G   D C5    1 
ATOM   1615  C  C6    . G   B 1 1   ? 84.519  89.807  131.266 1.00 46.08  ? 501  G   D C6    1 
ATOM   1616  O  O6    . G   B 1 1   ? 85.046  88.740  130.907 1.00 37.70  ? 501  G   D O6    1 
ATOM   1617  N  N1    . G   B 1 1   ? 84.949  91.013  130.725 1.00 33.03  ? 501  G   D N1    1 
ATOM   1618  C  C2    . G   B 1 1   ? 84.425  92.252  131.037 1.00 46.61  ? 501  G   D C2    1 
ATOM   1619  N  N2    . G   B 1 1   ? 84.959  93.298  130.388 1.00 45.98  ? 501  G   D N2    1 
ATOM   1620  N  N3    . G   B 1 1   ? 83.445  92.451  131.918 1.00 43.15  ? 501  G   D N3    1 
ATOM   1621  C  C4    . G   B 1 1   ? 83.021  91.290  132.465 1.00 50.46  ? 501  G   D C4    1 
ATOM   1622  P  P     . G   B 1 2   ? 77.034  92.310  131.738 1.00 41.69  ? 502  G   D P     1 
ATOM   1623  O  OP1   . G   B 1 2   ? 75.700  92.928  131.888 1.00 57.18  ? 502  G   D OP1   1 
ATOM   1624  O  OP2   . G   B 1 2   ? 77.122  90.899  131.354 1.00 40.45  ? 502  G   D OP2   1 
ATOM   1625  O  "O5'" . G   B 1 2   ? 77.833  93.189  130.683 1.00 43.55  ? 502  G   D "O5'" 1 
ATOM   1626  C  "C5'" . G   B 1 2   ? 77.811  94.607  130.775 1.00 42.90  ? 502  G   D "C5'" 1 
ATOM   1627  C  "C4'" . G   B 1 2   ? 78.636  95.217  129.682 1.00 46.42  ? 502  G   D "C4'" 1 
ATOM   1628  O  "O4'" . G   B 1 2   ? 80.044  94.969  129.933 1.00 41.38  ? 502  G   D "O4'" 1 
ATOM   1629  C  "C3'" . G   B 1 2   ? 78.385  94.663  128.288 1.00 39.78  ? 502  G   D "C3'" 1 
ATOM   1630  O  "O3'" . G   B 1 2   ? 77.268  95.310  127.685 1.00 38.20  ? 502  G   D "O3'" 1 
ATOM   1631  C  "C2'" . G   B 1 2   ? 79.686  95.022  127.589 1.00 41.14  ? 502  G   D "C2'" 1 
ATOM   1632  O  "O2'" . G   B 1 2   ? 79.725  96.396  127.251 1.00 31.74  ? 502  G   D "O2'" 1 
ATOM   1633  C  "C1'" . G   B 1 2   ? 80.707  94.757  128.701 1.00 41.92  ? 502  G   D "C1'" 1 
ATOM   1634  N  N9    . G   B 1 2   ? 81.202  93.389  128.716 1.00 43.83  ? 502  G   D N9    1 
ATOM   1635  C  C8    . G   B 1 2   ? 80.794  92.386  129.552 1.00 48.03  ? 502  G   D C8    1 
ATOM   1636  N  N7    . G   B 1 2   ? 81.427  91.265  129.355 1.00 43.38  ? 502  G   D N7    1 
ATOM   1637  C  C5    . G   B 1 2   ? 82.304  91.548  128.322 1.00 43.63  ? 502  G   D C5    1 
ATOM   1638  C  C6    . G   B 1 2   ? 83.249  90.715  127.674 1.00 43.35  ? 502  G   D C6    1 
ATOM   1639  O  O6    . G   B 1 2   ? 83.484  89.524  127.885 1.00 33.27  ? 502  G   D O6    1 
ATOM   1640  N  N1    . G   B 1 2   ? 83.946  91.406  126.686 1.00 40.90  ? 502  G   D N1    1 
ATOM   1641  C  C2    . G   B 1 2   ? 83.747  92.730  126.360 1.00 45.13  ? 502  G   D C2    1 
ATOM   1642  N  N2    . G   B 1 2   ? 84.532  93.234  125.400 1.00 47.95  ? 502  G   D N2    1 
ATOM   1643  N  N3    . G   B 1 2   ? 82.848  93.507  126.944 1.00 50.77  ? 502  G   D N3    1 
ATOM   1644  C  C4    . G   B 1 2   ? 82.172  92.854  127.912 1.00 43.91  ? 502  G   D C4    1 
ATOM   1645  P  P     . C   B 1 3   ? 76.289  94.473  126.727 1.00 42.62  ? 503  C   D P     1 
ATOM   1646  O  OP1   . C   B 1 3   ? 75.176  95.337  126.291 1.00 41.33  ? 503  C   D OP1   1 
ATOM   1647  O  OP2   . C   B 1 3   ? 76.003  93.206  127.418 1.00 38.30  ? 503  C   D OP2   1 
ATOM   1648  O  "O5'" . C   B 1 3   ? 77.199  94.159  125.467 1.00 43.26  ? 503  C   D "O5'" 1 
ATOM   1649  C  "C5'" . C   B 1 3   ? 77.704  95.215  124.667 1.00 34.51  ? 503  C   D "C5'" 1 
ATOM   1650  C  "C4'" . C   B 1 3   ? 78.712  94.680  123.687 1.00 40.20  ? 503  C   D "C4'" 1 
ATOM   1651  O  "O4'" . C   B 1 3   ? 79.915  94.271  124.399 1.00 42.74  ? 503  C   D "O4'" 1 
ATOM   1652  C  "C3'" . C   B 1 3   ? 78.292  93.427  122.929 1.00 41.17  ? 503  C   D "C3'" 1 
ATOM   1653  O  "O3'" . C   B 1 3   ? 77.498  93.756  121.804 1.00 42.24  ? 503  C   D "O3'" 1 
ATOM   1654  C  "C2'" . C   B 1 3   ? 79.643  92.875  122.501 1.00 45.57  ? 503  C   D "C2'" 1 
ATOM   1655  O  "O2'" . C   B 1 3   ? 80.204  93.602  121.424 1.00 40.36  ? 503  C   D "O2'" 1 
ATOM   1656  C  "C1'" . C   B 1 3   ? 80.474  93.135  123.757 1.00 42.68  ? 503  C   D "C1'" 1 
ATOM   1657  N  N1    . C   B 1 3   ? 80.410  91.994  124.681 1.00 47.57  ? 503  C   D N1    1 
ATOM   1658  C  C2    . C   B 1 3   ? 81.328  90.950  124.502 1.00 47.08  ? 503  C   D C2    1 
ATOM   1659  O  O2    . C   B 1 3   ? 82.136  91.032  123.576 1.00 39.22  ? 503  C   D O2    1 
ATOM   1660  N  N3    . C   B 1 3   ? 81.308  89.885  125.341 1.00 43.28  ? 503  C   D N3    1 
ATOM   1661  C  C4    . C   B 1 3   ? 80.417  89.844  126.336 1.00 51.08  ? 503  C   D C4    1 
ATOM   1662  N  N4    . C   B 1 3   ? 80.464  88.783  127.168 1.00 25.98  ? 503  C   D N4    1 
ATOM   1663  C  C5    . C   B 1 3   ? 79.446  90.896  126.532 1.00 41.74  ? 503  C   D C5    1 
ATOM   1664  C  C6    . C   B 1 3   ? 79.484  91.940  125.690 1.00 36.47  ? 503  C   D C6    1 
ATOM   1665  P  P     . C   B 1 4   ? 76.406  92.716  121.266 1.00 40.09  ? 504  C   D P     1 
ATOM   1666  O  OP1   . C   B 1 4   ? 75.600  93.428  120.243 1.00 39.92  ? 504  C   D OP1   1 
ATOM   1667  O  OP2   . C   B 1 4   ? 75.711  92.075  122.411 1.00 47.80  ? 504  C   D OP2   1 
ATOM   1668  O  "O5'" . C   B 1 4   ? 77.270  91.571  120.580 1.00 40.18  ? 504  C   D "O5'" 1 
ATOM   1669  C  "C5'" . C   B 1 4   ? 78.073  91.829  119.438 1.00 38.53  ? 504  C   D "C5'" 1 
ATOM   1670  C  "C4'" . C   B 1 4   ? 78.910  90.607  119.097 1.00 38.18  ? 504  C   D "C4'" 1 
ATOM   1671  O  "O4'" . C   B 1 4   ? 79.851  90.345  120.175 1.00 41.30  ? 504  C   D "O4'" 1 
ATOM   1672  C  "C3'" . C   B 1 4   ? 78.159  89.295  118.981 1.00 39.69  ? 504  C   D "C3'" 1 
ATOM   1673  O  "O3'" . C   B 1 4   ? 77.528  89.164  117.724 1.00 32.51  ? 504  C   D "O3'" 1 
ATOM   1674  C  "C2'" . C   B 1 4   ? 79.277  88.283  119.187 1.00 31.88  ? 504  C   D "C2'" 1 
ATOM   1675  O  "O2'" . C   B 1 4   ? 80.160  88.202  118.095 1.00 39.81  ? 504  C   D "O2'" 1 
ATOM   1676  C  "C1'" . C   B 1 4   ? 80.048  88.950  120.316 1.00 40.15  ? 504  C   D "C1'" 1 
ATOM   1677  N  N1    . C   B 1 4   ? 79.592  88.530  121.653 1.00 47.27  ? 504  C   D N1    1 
ATOM   1678  C  C2    . C   B 1 4   ? 80.102  87.336  122.190 1.00 43.42  ? 504  C   D C2    1 
ATOM   1679  O  O2    . C   B 1 4   ? 80.894  86.666  121.513 1.00 46.93  ? 504  C   D O2    1 
ATOM   1680  N  N3    . C   B 1 4   ? 79.715  86.944  123.422 1.00 45.37  ? 504  C   D N3    1 
ATOM   1681  C  C4    . C   B 1 4   ? 78.840  87.682  124.114 1.00 54.18  ? 504  C   D C4    1 
ATOM   1682  N  N4    . C   B 1 4   ? 78.485  87.253  125.337 1.00 39.66  ? 504  C   D N4    1 
ATOM   1683  C  C5    . C   B 1 4   ? 78.291  88.894  123.587 1.00 45.37  ? 504  C   D C5    1 
ATOM   1684  C  C6    . C   B 1 4   ? 78.694  89.278  122.364 1.00 49.14  ? 504  C   D C6    1 
ATOM   1685  P  P     . C   B 1 5   ? 76.238  88.228  117.593 1.00 38.56  ? 505  C   D P     1 
ATOM   1686  O  OP1   . C   B 1 5   ? 75.568  88.435  116.289 1.00 40.14  ? 505  C   D OP1   1 
ATOM   1687  O  OP2   . C   B 1 5   ? 75.472  88.424  118.839 1.00 44.89  ? 505  C   D OP2   1 
ATOM   1688  O  "O5'" . C   B 1 5   ? 76.857  86.755  117.617 1.00 44.18  ? 505  C   D "O5'" 1 
ATOM   1689  C  "C5'" . C   B 1 5   ? 77.760  86.320  116.608 1.00 36.64  ? 505  C   D "C5'" 1 
ATOM   1690  C  "C4'" . C   B 1 5   ? 78.270  84.939  116.920 1.00 39.69  ? 505  C   D "C4'" 1 
ATOM   1691  O  "O4'" . C   B 1 5   ? 79.040  84.964  118.155 1.00 42.72  ? 505  C   D "O4'" 1 
ATOM   1692  C  "C3'" . C   B 1 5   ? 77.206  83.898  117.216 1.00 45.12  ? 505  C   D "C3'" 1 
ATOM   1693  O  "O3'" . C   B 1 5   ? 76.610  83.399  116.044 1.00 39.35  ? 505  C   D "O3'" 1 
ATOM   1694  C  "C2'" . C   B 1 5   ? 78.026  82.845  117.939 1.00 45.34  ? 505  C   D "C2'" 1 
ATOM   1695  O  "O2'" . C   B 1 5   ? 78.902  82.156  117.076 1.00 39.00  ? 505  C   D "O2'" 1 
ATOM   1696  C  "C1'" . C   B 1 5   ? 78.868  83.732  118.849 1.00 46.25  ? 505  C   D "C1'" 1 
ATOM   1697  N  N1    . C   B 1 5   ? 78.199  83.995  120.138 1.00 48.29  ? 505  C   D N1    1 
ATOM   1698  C  C2    . C   B 1 5   ? 78.398  83.094  121.193 1.00 44.77  ? 505  C   D C2    1 
ATOM   1699  O  O2    . C   B 1 5   ? 79.070  82.080  120.994 1.00 43.92  ? 505  C   D O2    1 
ATOM   1700  N  N3    . C   B 1 5   ? 77.847  83.355  122.400 1.00 41.58  ? 505  C   D N3    1 
ATOM   1701  C  C4    . C   B 1 5   ? 77.113  84.455  122.577 1.00 45.30  ? 505  C   D C4    1 
ATOM   1702  N  N4    . C   B 1 5   ? 76.636  84.692  123.808 1.00 32.98  ? 505  C   D N4    1 
ATOM   1703  C  C5    . C   B 1 5   ? 76.851  85.365  121.508 1.00 29.97  ? 505  C   D C5    1 
ATOM   1704  C  C6    . C   B 1 5   ? 77.410  85.100  120.318 1.00 43.24  ? 505  C   D C6    1 
ATOM   1705  P  P     . C   B 1 6   ? 75.168  82.698  116.125 1.00 45.61  ? 506  C   D P     1 
ATOM   1706  O  OP1   . C   B 1 6   ? 74.815  82.286  114.748 1.00 35.81  ? 506  C   D OP1   1 
ATOM   1707  O  OP2   . C   B 1 6   ? 74.233  83.544  116.890 1.00 42.98  ? 506  C   D OP2   1 
ATOM   1708  O  "O5'" . C   B 1 6   ? 75.419  81.396  117.002 1.00 44.25  ? 506  C   D "O5'" 1 
ATOM   1709  C  "C5'" . C   B 1 6   ? 76.241  80.355  116.524 1.00 40.52  ? 506  C   D "C5'" 1 
ATOM   1710  C  "C4'" . C   B 1 6   ? 76.399  79.307  117.583 1.00 37.54  ? 506  C   D "C4'" 1 
ATOM   1711  O  "O4'" . C   B 1 6   ? 76.994  79.897  118.760 1.00 37.41  ? 506  C   D "O4'" 1 
ATOM   1712  C  "C3'" . C   B 1 6   ? 75.111  78.695  118.083 1.00 35.42  ? 506  C   D "C3'" 1 
ATOM   1713  O  "O3'" . C   B 1 6   ? 74.738  77.665  117.190 1.00 38.07  ? 506  C   D "O3'" 1 
ATOM   1714  C  "C2'" . C   B 1 6   ? 75.541  78.156  119.438 1.00 45.12  ? 506  C   D "C2'" 1 
ATOM   1715  O  "O2'" . C   B 1 6   ? 76.269  76.948  119.354 1.00 45.96  ? 506  C   D "O2'" 1 
ATOM   1716  C  "C1'" . C   B 1 6   ? 76.490  79.258  119.908 1.00 49.46  ? 506  C   D "C1'" 1 
ATOM   1717  N  N1    . C   B 1 6   ? 75.827  80.267  120.736 1.00 60.79  ? 506  C   D N1    1 
ATOM   1718  C  C2    . C   B 1 6   ? 75.559  79.961  122.071 1.00 65.06  ? 506  C   D C2    1 
ATOM   1719  O  O2    . C   B 1 6   ? 75.883  78.844  122.504 1.00 59.97  ? 506  C   D O2    1 
ATOM   1720  N  N3    . C   B 1 6   ? 74.959  80.886  122.852 1.00 62.99  ? 506  C   D N3    1 
ATOM   1721  C  C4    . C   B 1 6   ? 74.635  82.074  122.344 1.00 62.19  ? 506  C   D C4    1 
ATOM   1722  N  N4    . C   B 1 6   ? 74.065  82.966  123.157 1.00 64.05  ? 506  C   D N4    1 
ATOM   1723  C  C5    . C   B 1 6   ? 74.888  82.406  120.981 1.00 58.80  ? 506  C   D C5    1 
ATOM   1724  C  C6    . C   B 1 6   ? 75.480  81.483  120.221 1.00 62.08  ? 506  C   D C6    1 
ATOM   1725  P  P     . A   B 1 7   ? 73.251  77.051  117.234 1.00 57.99  ? 507  A   D P     1 
ATOM   1726  O  OP1   . A   B 1 7   ? 73.157  76.028  116.157 1.00 47.87  ? 507  A   D OP1   1 
ATOM   1727  O  OP2   . A   B 1 7   ? 72.279  78.163  117.267 1.00 54.86  ? 507  A   D OP2   1 
ATOM   1728  O  "O5'" . A   B 1 7   ? 73.181  76.298  118.636 1.00 58.98  ? 507  A   D "O5'" 1 
ATOM   1729  C  "C5'" . A   B 1 7   ? 74.133  75.292  118.968 1.00 69.07  ? 507  A   D "C5'" 1 
ATOM   1730  C  "C4'" . A   B 1 7   ? 73.642  74.472  120.129 1.00 75.58  ? 507  A   D "C4'" 1 
ATOM   1731  O  "O4'" . A   B 1 7   ? 73.635  75.288  121.333 1.00 75.91  ? 507  A   D "O4'" 1 
ATOM   1732  C  "C3'" . A   B 1 7   ? 72.203  74.032  119.941 1.00 82.66  ? 507  A   D "C3'" 1 
ATOM   1733  O  "O3'" . A   B 1 7   ? 71.930  72.664  119.698 1.00 86.74  ? 507  A   D "O3'" 1 
ATOM   1734  C  "C2'" . A   B 1 7   ? 71.314  74.984  120.736 1.00 81.37  ? 507  A   D "C2'" 1 
ATOM   1735  O  "O2'" . A   B 1 7   ? 70.313  74.327  121.484 1.00 81.35  ? 507  A   D "O2'" 1 
ATOM   1736  C  "C1'" . A   B 1 7   ? 72.303  75.578  121.735 1.00 80.60  ? 507  A   D "C1'" 1 
ATOM   1737  N  N9    . A   B 1 7   ? 72.162  77.022  121.918 1.00 86.89  ? 507  A   D N9    1 
ATOM   1738  C  C8    . A   B 1 7   ? 72.325  78.034  121.001 1.00 90.34  ? 507  A   D C8    1 
ATOM   1739  N  N7    . A   B 1 7   ? 72.128  79.235  121.498 1.00 83.17  ? 507  A   D N7    1 
ATOM   1740  C  C5    . A   B 1 7   ? 71.813  78.996  122.829 1.00 88.49  ? 507  A   D C5    1 
ATOM   1741  C  C6    . A   B 1 7   ? 71.498  79.857  123.902 1.00 88.92  ? 507  A   D C6    1 
ATOM   1742  N  N6    . A   B 1 7   ? 71.464  81.185  123.805 1.00 80.79  ? 507  A   D N6    1 
ATOM   1743  N  N1    . A   B 1 7   ? 71.222  79.296  125.098 1.00 88.00  ? 507  A   D N1    1 
ATOM   1744  C  C2    . A   B 1 7   ? 71.272  77.964  125.205 1.00 93.53  ? 507  A   D C2    1 
ATOM   1745  N  N3    . A   B 1 7   ? 71.564  77.051  124.277 1.00 94.89  ? 507  A   D N3    1 
ATOM   1746  C  C4    . A   B 1 7   ? 71.826  77.639  123.098 1.00 89.97  ? 507  A   D C4    1 
ATOM   1747  P  P     . U   B 1 8   ? 72.194  71.595  120.854 1.00 79.44  ? 508  U   D P     1 
ATOM   1748  O  OP1   . U   B 1 8   ? 72.213  72.285  122.168 1.00 84.55  ? 508  U   D OP1   1 
ATOM   1749  O  OP2   . U   B 1 8   ? 73.380  70.834  120.410 1.00 78.35  ? 508  U   D OP2   1 
ATOM   1750  O  "O5'" . U   B 1 8   ? 70.914  70.659  120.761 1.00 75.35  ? 508  U   D "O5'" 1 
ATOM   1751  C  "C5'" . U   B 1 8   ? 69.672  71.048  121.332 1.00 57.50  ? 508  U   D "C5'" 1 
ATOM   1752  C  "C4'" . U   B 1 8   ? 68.707  69.890  121.278 1.00 51.12  ? 508  U   D "C4'" 1 
ATOM   1753  O  "O4'" . U   B 1 8   ? 68.135  69.803  119.952 1.00 45.55  ? 508  U   D "O4'" 1 
ATOM   1754  C  "C3'" . U   B 1 8   ? 69.354  68.535  121.509 1.00 38.72  ? 508  U   D "C3'" 1 
ATOM   1755  O  "O3'" . U   B 1 8   ? 69.463  68.246  122.893 1.00 37.94  ? 508  U   D "O3'" 1 
ATOM   1756  C  "C2'" . U   B 1 8   ? 68.388  67.620  120.791 1.00 42.03  ? 508  U   D "C2'" 1 
ATOM   1757  O  "O2'" . U   B 1 8   ? 67.209  67.464  121.546 1.00 48.62  ? 508  U   D "O2'" 1 
ATOM   1758  C  "C1'" . U   B 1 8   ? 68.070  68.451  119.549 1.00 44.05  ? 508  U   D "C1'" 1 
ATOM   1759  N  N1    . U   B 1 8   ? 69.033  68.272  118.450 1.00 46.59  ? 508  U   D N1    1 
ATOM   1760  C  C2    . U   B 1 8   ? 68.731  67.341  117.501 1.00 35.30  ? 508  U   D C2    1 
ATOM   1761  O  O2    . U   B 1 8   ? 67.738  66.661  117.558 1.00 52.54  ? 508  U   D O2    1 
ATOM   1762  N  N3    . U   B 1 8   ? 69.630  67.236  116.482 1.00 46.17  ? 508  U   D N3    1 
ATOM   1763  C  C4    . U   B 1 8   ? 70.794  67.957  116.317 1.00 46.75  ? 508  U   D C4    1 
ATOM   1764  O  O4    . U   B 1 8   ? 71.474  67.787  115.301 1.00 45.40  ? 508  U   D O4    1 
ATOM   1765  C  C5    . U   B 1 8   ? 71.056  68.897  117.359 1.00 45.69  ? 508  U   D C5    1 
ATOM   1766  C  C6    . U   B 1 8   ? 70.186  69.019  118.368 1.00 36.08  ? 508  U   D C6    1 
ATOM   1767  P  P     . C   B 1 9   ? 70.816  67.604  123.464 1.00 54.08  ? 509  C   D P     1 
ATOM   1768  O  OP1   . C   B 1 9   ? 70.775  67.805  124.929 1.00 63.36  ? 509  C   D OP1   1 
ATOM   1769  O  OP2   . C   B 1 9   ? 71.981  68.109  122.692 1.00 52.33  ? 509  C   D OP2   1 
ATOM   1770  O  "O5'" . C   B 1 9   ? 70.650  66.055  123.125 1.00 50.38  ? 509  C   D "O5'" 1 
ATOM   1771  C  "C5'" . C   B 1 9   ? 71.431  65.067  123.773 1.00 35.94  ? 509  C   D "C5'" 1 
ATOM   1772  C  "C4'" . C   B 1 9   ? 70.522  64.050  124.406 1.00 43.26  ? 509  C   D "C4'" 1 
ATOM   1773  O  "O4'" . C   B 1 9   ? 69.730  63.422  123.367 1.00 42.72  ? 509  C   D "O4'" 1 
ATOM   1774  C  "C3'" . C   B 1 9   ? 71.348  62.926  125.031 1.00 39.36  ? 509  C   D "C3'" 1 
ATOM   1775  O  "O3'" . C   B 1 9   ? 70.942  62.596  126.347 1.00 39.85  ? 509  C   D "O3'" 1 
ATOM   1776  C  "C2'" . C   B 1 9   ? 71.332  61.771  124.031 1.00 48.64  ? 509  C   D "C2'" 1 
ATOM   1777  O  "O2'" . C   B 1 9   ? 71.209  60.504  124.646 1.00 47.72  ? 509  C   D "O2'" 1 
ATOM   1778  C  "C1'" . C   B 1 9   ? 70.031  62.049  123.293 1.00 37.18  ? 509  C   D "C1'" 1 
ATOM   1779  N  N1    . C   B 1 9   ? 69.805  61.542  121.936 1.00 52.29  ? 509  C   D N1    1 
ATOM   1780  C  C2    . C   B 1 9   ? 68.722  60.668  121.740 1.00 51.69  ? 509  C   D C2    1 
ATOM   1781  O  O2    . C   B 1 9   ? 68.017  60.366  122.713 1.00 53.61  ? 509  C   D O2    1 
ATOM   1782  N  N3    . C   B 1 9   ? 68.474  60.181  120.503 1.00 41.71  ? 509  C   D N3    1 
ATOM   1783  C  C4    . C   B 1 9   ? 69.260  60.531  119.481 1.00 46.35  ? 509  C   D C4    1 
ATOM   1784  N  N4    . C   B 1 9   ? 68.979  60.025  118.266 1.00 32.90  ? 509  C   D N4    1 
ATOM   1785  C  C5    . C   B 1 9   ? 70.373  61.417  119.651 1.00 40.53  ? 509  C   D C5    1 
ATOM   1786  C  C6    . C   B 1 9   ? 70.607  61.895  120.886 1.00 54.32  ? 509  C   D C6    1 
ATOM   1787  P  P     . G   B 1 10  ? 71.421  63.480  127.588 1.00 44.09  ? 510  G   D P     1 
ATOM   1788  O  OP1   . G   B 1 10  ? 70.849  62.832  128.791 1.00 43.91  ? 510  G   D OP1   1 
ATOM   1789  O  OP2   . G   B 1 10  ? 71.119  64.912  127.300 1.00 41.77  ? 510  G   D OP2   1 
ATOM   1790  O  "O5'" . G   B 1 10  ? 72.998  63.284  127.658 1.00 35.75  ? 510  G   D "O5'" 1 
ATOM   1791  C  "C5'" . G   B 1 10  ? 73.751  63.977  128.639 1.00 43.60  ? 510  G   D "C5'" 1 
ATOM   1792  C  "C4'" . G   B 1 10  ? 75.214  63.662  128.482 1.00 54.28  ? 510  G   D "C4'" 1 
ATOM   1793  O  "O4'" . G   B 1 10  ? 75.385  62.222  128.615 1.00 46.05  ? 510  G   D "O4'" 1 
ATOM   1794  C  "C3'" . G   B 1 10  ? 75.795  64.003  127.116 1.00 45.04  ? 510  G   D "C3'" 1 
ATOM   1795  O  "O3'" . G   B 1 10  ? 76.305  65.331  127.081 1.00 38.14  ? 510  G   D "O3'" 1 
ATOM   1796  C  "C2'" . G   B 1 10  ? 76.928  63.010  127.023 1.00 45.31  ? 510  G   D "C2'" 1 
ATOM   1797  O  "O2'" . G   B 1 10  ? 77.986  63.458  127.844 1.00 45.63  ? 510  G   D "O2'" 1 
ATOM   1798  C  "C1'" . G   B 1 10  ? 76.277  61.763  127.628 1.00 47.15  ? 510  G   D "C1'" 1 
ATOM   1799  N  N9    . G   B 1 10  ? 75.507  60.965  126.676 1.00 50.13  ? 510  G   D N9    1 
ATOM   1800  C  C8    . G   B 1 10  ? 74.145  60.745  126.685 1.00 52.90  ? 510  G   D C8    1 
ATOM   1801  N  N7    . G   B 1 10  ? 73.745  59.961  125.715 1.00 48.51  ? 510  G   D N7    1 
ATOM   1802  C  C5    . G   B 1 10  ? 74.910  59.643  125.026 1.00 42.15  ? 510  G   D C5    1 
ATOM   1803  C  C6    . G   B 1 10  ? 75.109  58.835  123.880 1.00 42.16  ? 510  G   D C6    1 
ATOM   1804  O  O6    . G   B 1 10  ? 74.266  58.195  123.225 1.00 48.77  ? 510  G   D O6    1 
ATOM   1805  N  N1    . G   B 1 10  ? 76.448  58.802  123.503 1.00 30.13  ? 510  G   D N1    1 
ATOM   1806  C  C2    . G   B 1 10  ? 77.463  59.447  124.148 1.00 44.36  ? 510  G   D C2    1 
ATOM   1807  N  N2    . G   B 1 10  ? 78.689  59.266  123.648 1.00 46.09  ? 510  G   D N2    1 
ATOM   1808  N  N3    . G   B 1 10  ? 77.297  60.211  125.213 1.00 44.33  ? 510  G   D N3    1 
ATOM   1809  C  C4    . G   B 1 10  ? 76.004  60.263  125.597 1.00 47.88  ? 510  G   D C4    1 
ATOM   1810  P  P     . U   B 1 11  ? 76.236  66.180  125.702 1.00 49.24  ? 511  U   D P     1 
ATOM   1811  O  OP1   . U   B 1 11  ? 76.782  67.533  125.964 1.00 41.43  ? 511  U   D OP1   1 
ATOM   1812  O  OP2   . U   B 1 11  ? 74.893  66.038  125.091 1.00 32.93  ? 511  U   D OP2   1 
ATOM   1813  O  "O5'" . U   B 1 11  ? 77.253  65.434  124.734 1.00 40.01  ? 511  U   D "O5'" 1 
ATOM   1814  C  "C5'" . U   B 1 11  ? 78.651  65.435  125.014 1.00 44.26  ? 511  U   D "C5'" 1 
ATOM   1815  C  "C4'" . U   B 1 11  ? 79.388  64.719  123.910 1.00 51.19  ? 511  U   D "C4'" 1 
ATOM   1816  O  "O4'" . U   B 1 11  ? 79.043  63.300  123.935 1.00 39.66  ? 511  U   D "O4'" 1 
ATOM   1817  C  "C3'" . U   B 1 11  ? 78.995  65.160  122.507 1.00 39.53  ? 511  U   D "C3'" 1 
ATOM   1818  O  "O3'" . U   B 1 11  ? 79.684  66.352  122.145 1.00 47.64  ? 511  U   D "O3'" 1 
ATOM   1819  C  "C2'" . U   B 1 11  ? 79.418  63.945  121.695 1.00 50.12  ? 511  U   D "C2'" 1 
ATOM   1820  O  "O2'" . U   B 1 11  ? 80.826  63.858  121.558 1.00 47.77  ? 511  U   D "O2'" 1 
ATOM   1821  C  "C1'" . U   B 1 11  ? 78.955  62.811  122.615 1.00 41.52  ? 511  U   D "C1'" 1 
ATOM   1822  N  N1    . U   B 1 11  ? 77.564  62.422  122.366 1.00 40.46  ? 511  U   D N1    1 
ATOM   1823  C  C2    . U   B 1 11  ? 77.322  61.652  121.248 1.00 36.29  ? 511  U   D C2    1 
ATOM   1824  O  O2    . U   B 1 11  ? 78.207  61.275  120.514 1.00 43.92  ? 511  U   D O2    1 
ATOM   1825  N  N3    . U   B 1 11  ? 76.013  61.326  121.032 1.00 35.06  ? 511  U   D N3    1 
ATOM   1826  C  C4    . U   B 1 11  ? 74.942  61.663  121.815 1.00 40.83  ? 511  U   D C4    1 
ATOM   1827  O  O4    . U   B 1 11  ? 73.829  61.242  121.512 1.00 49.40  ? 511  U   D O4    1 
ATOM   1828  C  C5    . U   B 1 11  ? 75.266  62.456  122.971 1.00 38.41  ? 511  U   D C5    1 
ATOM   1829  C  C6    . U   B 1 11  ? 76.541  62.802  123.200 1.00 35.68  ? 511  U   D C6    1 
ATOM   1830  P  P     . C   B 1 12  ? 79.060  67.337  121.032 1.00 35.20  ? 512  C   D P     1 
ATOM   1831  O  OP1   . C   B 1 12  ? 79.905  68.553  121.026 1.00 36.25  ? 512  C   D OP1   1 
ATOM   1832  O  OP2   . C   B 1 12  ? 77.606  67.461  121.215 1.00 34.99  ? 512  C   D OP2   1 
ATOM   1833  O  "O5'" . C   B 1 12  ? 79.255  66.554  119.662 1.00 42.47  ? 512  C   D "O5'" 1 
ATOM   1834  C  "C5'" . C   B 1 12  ? 80.546  66.243  119.161 1.00 36.62  ? 512  C   D "C5'" 1 
ATOM   1835  C  "C4'" . C   B 1 12  ? 80.409  65.603  117.805 1.00 37.68  ? 512  C   D "C4'" 1 
ATOM   1836  O  "O4'" . C   B 1 12  ? 79.873  64.262  117.949 1.00 40.02  ? 512  C   D "O4'" 1 
ATOM   1837  C  "C3'" . C   B 1 12  ? 79.407  66.283  116.896 1.00 31.35  ? 512  C   D "C3'" 1 
ATOM   1838  O  "O3'" . C   B 1 12  ? 79.938  67.437  116.268 1.00 35.82  ? 512  C   D "O3'" 1 
ATOM   1839  C  "C2'" . C   B 1 12  ? 79.054  65.167  115.924 1.00 34.00  ? 512  C   D "C2'" 1 
ATOM   1840  O  "O2'" . C   B 1 12  ? 80.038  64.927  114.940 1.00 34.68  ? 512  C   D "O2'" 1 
ATOM   1841  C  "C1'" . C   B 1 12  ? 79.012  63.966  116.867 1.00 37.45  ? 512  C   D "C1'" 1 
ATOM   1842  N  N1    . C   B 1 12  ? 77.667  63.742  117.409 1.00 40.19  ? 512  C   D N1    1 
ATOM   1843  C  C2    . C   B 1 12  ? 76.750  63.008  116.647 1.00 37.12  ? 512  C   D C2    1 
ATOM   1844  O  O2    . C   B 1 12  ? 77.108  62.570  115.543 1.00 35.57  ? 512  C   D O2    1 
ATOM   1845  N  N3    . C   B 1 12  ? 75.501  62.796  117.132 1.00 42.88  ? 512  C   D N3    1 
ATOM   1846  C  C4    . C   B 1 12  ? 75.160  63.287  118.328 1.00 41.58  ? 512  C   D C4    1 
ATOM   1847  N  N4    . C   B 1 12  ? 73.923  63.053  118.766 1.00 32.19  ? 512  C   D N4    1 
ATOM   1848  C  C5    . C   B 1 12  ? 76.080  64.042  119.127 1.00 38.73  ? 512  C   D C5    1 
ATOM   1849  C  C6    . C   B 1 12  ? 77.310  64.243  118.632 1.00 30.69  ? 512  C   D C6    1 
ATOM   1850  P  P     . U   B 1 13  ? 78.924  68.558  115.723 1.00 38.79  ? 513  U   D P     1 
ATOM   1851  O  OP1   . U   B 1 13  ? 79.680  69.485  114.845 1.00 43.50  ? 513  U   D OP1   1 
ATOM   1852  O  OP2   . U   B 1 13  ? 78.200  69.093  116.931 1.00 34.48  ? 513  U   D OP2   1 
ATOM   1853  O  "O5'" . U   B 1 13  ? 77.959  67.694  114.807 1.00 33.20  ? 513  U   D "O5'" 1 
ATOM   1854  C  "C5'" . U   B 1 13  ? 76.672  68.113  114.448 1.00 23.69  ? 513  U   D "C5'" 1 
ATOM   1855  C  "C4'" . U   B 1 13  ? 75.956  66.964  113.787 1.00 34.47  ? 513  U   D "C4'" 1 
ATOM   1856  O  "O4'" . U   B 1 13  ? 75.782  65.868  114.734 1.00 41.58  ? 513  U   D "O4'" 1 
ATOM   1857  C  "C3'" . U   B 1 13  ? 74.547  67.246  113.303 1.00 37.13  ? 513  U   D "C3'" 1 
ATOM   1858  O  "O3'" . U   B 1 13  ? 74.608  67.914  112.044 1.00 47.41  ? 513  U   D "O3'" 1 
ATOM   1859  C  "C2'" . U   B 1 13  ? 73.971  65.840  113.195 1.00 34.58  ? 513  U   D "C2'" 1 
ATOM   1860  O  "O2'" . U   B 1 13  ? 74.411  65.152  112.038 1.00 35.03  ? 513  U   D "O2'" 1 
ATOM   1861  C  "C1'" . U   B 1 13  ? 74.577  65.168  114.429 1.00 36.86  ? 513  U   D "C1'" 1 
ATOM   1862  N  N1    . U   B 1 13  ? 73.681  65.219  115.598 1.00 45.16  ? 513  U   D N1    1 
ATOM   1863  C  C2    . U   B 1 13  ? 72.498  64.497  115.543 1.00 38.73  ? 513  U   D C2    1 
ATOM   1864  O  O2    . U   B 1 13  ? 72.184  63.836  114.581 1.00 32.32  ? 513  U   D O2    1 
ATOM   1865  N  N3    . U   B 1 13  ? 71.695  64.597  116.653 1.00 30.47  ? 513  U   D N3    1 
ATOM   1866  C  C4    . U   B 1 13  ? 71.948  65.334  117.787 1.00 40.39  ? 513  U   D C4    1 
ATOM   1867  O  O4    . U   B 1 13  ? 71.132  65.341  118.704 1.00 37.73  ? 513  U   D O4    1 
ATOM   1868  C  C5    . U   B 1 13  ? 73.190  66.049  117.771 1.00 43.59  ? 513  U   D C5    1 
ATOM   1869  C  C6    . U   B 1 13  ? 73.993  65.967  116.706 1.00 47.58  ? 513  U   D C6    1 
ATOM   1870  P  P     . A   B 1 14  ? 73.439  68.939  111.626 1.00 41.75  ? 514  A   D P     1 
ATOM   1871  O  OP1   . A   B 1 14  ? 73.927  69.789  110.515 1.00 54.43  ? 514  A   D OP1   1 
ATOM   1872  O  OP2   . A   B 1 14  ? 72.969  69.582  112.884 1.00 44.17  ? 514  A   D OP2   1 
ATOM   1873  O  "O5'" . A   B 1 14  ? 72.328  67.967  111.031 1.00 41.10  ? 514  A   D "O5'" 1 
ATOM   1874  C  "C5'" . A   B 1 14  ? 72.671  67.041  110.015 1.00 44.42  ? 514  A   D "C5'" 1 
ATOM   1875  C  "C4'" . A   B 1 14  ? 71.480  66.187  109.643 1.00 56.28  ? 514  A   D "C4'" 1 
ATOM   1876  O  "O4'" . A   B 1 14  ? 71.143  65.285  110.723 1.00 54.99  ? 514  A   D "O4'" 1 
ATOM   1877  C  "C3'" . A   B 1 14  ? 70.176  66.912  109.367 1.00 55.07  ? 514  A   D "C3'" 1 
ATOM   1878  O  "O3'" . A   B 1 14  ? 70.174  67.415  108.040 1.00 46.93  ? 514  A   D "O3'" 1 
ATOM   1879  C  "C2'" . A   B 1 14  ? 69.154  65.788  109.522 1.00 51.52  ? 514  A   D "C2'" 1 
ATOM   1880  O  "O2'" . A   B 1 14  ? 69.069  64.961  108.385 1.00 43.34  ? 514  A   D "O2'" 1 
ATOM   1881  C  "C1'" . A   B 1 14  ? 69.764  64.969  110.654 1.00 51.77  ? 514  A   D "C1'" 1 
ATOM   1882  N  N9    . A   B 1 14  ? 69.163  65.226  111.957 1.00 44.76  ? 514  A   D N9    1 
ATOM   1883  C  C8    . A   B 1 14  ? 69.714  65.880  113.027 1.00 46.96  ? 514  A   D C8    1 
ATOM   1884  N  N7    . A   B 1 14  ? 68.947  65.901  114.082 1.00 43.34  ? 514  A   D N7    1 
ATOM   1885  C  C5    . A   B 1 14  ? 67.807  65.229  113.676 1.00 46.68  ? 514  A   D C5    1 
ATOM   1886  C  C6    . A   B 1 14  ? 66.620  64.907  114.344 1.00 41.15  ? 514  A   D C6    1 
ATOM   1887  N  N6    . A   B 1 14  ? 66.380  65.228  115.615 1.00 39.83  ? 514  A   D N6    1 
ATOM   1888  N  N1    . A   B 1 14  ? 65.680  64.232  113.657 1.00 36.42  ? 514  A   D N1    1 
ATOM   1889  C  C2    . A   B 1 14  ? 65.925  63.908  112.373 1.00 38.95  ? 514  A   D C2    1 
ATOM   1890  N  N3    . A   B 1 14  ? 67.006  64.150  111.638 1.00 42.80  ? 514  A   D N3    1 
ATOM   1891  C  C4    . A   B 1 14  ? 67.922  64.819  112.362 1.00 43.39  ? 514  A   D C4    1 
ATOM   1892  P  P     . G   B 1 15  ? 69.466  68.820  107.725 1.00 57.60  ? 515  G   D P     1 
ATOM   1893  O  OP1   . G   B 1 15  ? 69.485  68.908  106.235 1.00 41.54  ? 515  G   D OP1   1 
ATOM   1894  O  OP2   . G   B 1 15  ? 70.145  69.841  108.544 1.00 35.84  ? 515  G   D OP2   1 
ATOM   1895  O  "O5'" . G   B 1 15  ? 67.966  68.629  108.248 1.00 53.53  ? 515  G   D "O5'" 1 
ATOM   1896  C  "C5'" . G   B 1 15  ? 67.198  67.540  107.752 1.00 61.14  ? 515  G   D "C5'" 1 
ATOM   1897  C  "C4'" . G   B 1 15  ? 65.918  67.329  108.535 1.00 63.67  ? 515  G   D "C4'" 1 
ATOM   1898  O  "O4'" . G   B 1 15  ? 66.202  67.099  109.952 1.00 52.16  ? 515  G   D "O4'" 1 
ATOM   1899  C  "C3'" . G   B 1 15  ? 65.054  68.586  108.492 1.00 66.02  ? 515  G   D "C3'" 1 
ATOM   1900  O  "O3'" . G   B 1 15  ? 63.722  68.328  108.067 1.00 85.32  ? 515  G   D "O3'" 1 
ATOM   1901  C  "C2'" . G   B 1 15  ? 65.258  69.295  109.826 1.00 48.43  ? 515  G   D "C2'" 1 
ATOM   1902  O  "O2'" . G   B 1 15  ? 64.083  69.810  110.397 1.00 60.66  ? 515  G   D "O2'" 1 
ATOM   1903  C  "C1'" . G   B 1 15  ? 65.637  68.128  110.721 1.00 44.55  ? 515  G   D "C1'" 1 
ATOM   1904  N  N9    . G   B 1 15  ? 66.434  68.436  111.891 1.00 43.13  ? 515  G   D N9    1 
ATOM   1905  C  C8    . G   B 1 15  ? 67.716  68.903  111.921 1.00 47.69  ? 515  G   D C8    1 
ATOM   1906  N  N7    . G   B 1 15  ? 68.110  69.229  113.119 1.00 51.37  ? 515  G   D N7    1 
ATOM   1907  C  C5    . G   B 1 15  ? 67.030  68.928  113.933 1.00 42.71  ? 515  G   D C5    1 
ATOM   1908  C  C6    . G   B 1 15  ? 66.863  69.094  115.343 1.00 50.24  ? 515  G   D C6    1 
ATOM   1909  O  O6    . G   B 1 15  ? 67.650  69.589  116.167 1.00 46.12  ? 515  G   D O6    1 
ATOM   1910  N  N1    . G   B 1 15  ? 65.623  68.631  115.767 1.00 46.93  ? 515  G   D N1    1 
ATOM   1911  C  C2    . G   B 1 15  ? 64.657  68.099  114.941 1.00 56.68  ? 515  G   D C2    1 
ATOM   1912  N  N2    . G   B 1 15  ? 63.521  67.706  115.552 1.00 52.78  ? 515  G   D N2    1 
ATOM   1913  N  N3    . G   B 1 15  ? 64.794  67.963  113.619 1.00 41.35  ? 515  G   D N3    1 
ATOM   1914  C  C4    . G   B 1 15  ? 66.001  68.397  113.193 1.00 41.26  ? 515  G   D C4    1 
ATOM   1915  P  P     . C   B 1 16  ? 63.027  69.275  106.983 1.00 100.28 ? 516  C   D P     1 
ATOM   1916  O  OP1   . C   B 1 16  ? 61.594  68.893  106.915 1.00 99.12  ? 516  C   D OP1   1 
ATOM   1917  O  OP2   . C   B 1 16  ? 63.860  69.239  105.750 1.00 99.79  ? 516  C   D OP2   1 
ATOM   1918  O  "O5'" . C   B 1 16  ? 63.127  70.724  107.634 1.00 101.89 ? 516  C   D "O5'" 1 
ATOM   1919  C  "C5'" . C   B 1 16  ? 62.526  71.843  107.000 1.00 110.14 ? 516  C   D "C5'" 1 
ATOM   1920  C  "C4'" . C   B 1 16  ? 63.248  73.102  107.389 1.00 111.53 ? 516  C   D "C4'" 1 
ATOM   1921  O  "O4'" . C   B 1 16  ? 64.641  73.004  106.991 1.00 114.01 ? 516  C   D "O4'" 1 
ATOM   1922  C  "C3'" . C   B 1 16  ? 62.753  74.365  106.707 1.00 111.46 ? 516  C   D "C3'" 1 
ATOM   1923  O  "O3'" . C   B 1 16  ? 61.641  74.897  107.418 1.00 104.87 ? 516  C   D "O3'" 1 
ATOM   1924  C  "C2'" . C   B 1 16  ? 63.966  75.275  106.843 1.00 117.42 ? 516  C   D "C2'" 1 
ATOM   1925  O  "O2'" . C   B 1 16  ? 64.080  75.817  108.144 1.00 127.35 ? 516  C   D "O2'" 1 
ATOM   1926  C  "C1'" . C   B 1 16  ? 65.112  74.288  106.612 1.00 121.09 ? 516  C   D "C1'" 1 
ATOM   1927  N  N1    . C   B 1 16  ? 65.526  74.240  105.201 1.00 127.59 ? 516  C   D N1    1 
ATOM   1928  C  C2    . C   B 1 16  ? 66.407  75.225  104.720 1.00 127.89 ? 516  C   D C2    1 
ATOM   1929  O  O2    . C   B 1 16  ? 66.824  76.095  105.504 1.00 125.59 ? 516  C   D O2    1 
ATOM   1930  N  N3    . C   B 1 16  ? 66.780  75.201  103.418 1.00 128.95 ? 516  C   D N3    1 
ATOM   1931  C  C4    . C   B 1 16  ? 66.312  74.244  102.608 1.00 130.78 ? 516  C   D C4    1 
ATOM   1932  N  N4    . C   B 1 16  ? 66.705  74.259  101.328 1.00 130.96 ? 516  C   D N4    1 
ATOM   1933  C  C5    . C   B 1 16  ? 65.421  73.228  103.072 1.00 129.27 ? 516  C   D C5    1 
ATOM   1934  C  C6    . C   B 1 16  ? 65.058  73.263  104.363 1.00 129.29 ? 516  C   D C6    1 
ATOM   1935  P  P     . G   B 1 17  ? 60.222  75.058  106.685 1.00 93.64  ? 518  G   D P     1 
ATOM   1936  O  OP1   . G   B 1 17  ? 60.243  74.382  105.361 1.00 93.83  ? 518  G   D OP1   1 
ATOM   1937  O  OP2   . G   B 1 17  ? 59.884  76.496  106.769 1.00 86.38  ? 518  G   D OP2   1 
ATOM   1938  O  "O5'" . G   B 1 17  ? 59.233  74.262  107.641 1.00 94.41  ? 518  G   D "O5'" 1 
ATOM   1939  C  "C5'" . G   B 1 17  ? 58.807  74.833  108.862 1.00 88.06  ? 518  G   D "C5'" 1 
ATOM   1940  C  "C4'" . G   B 1 17  ? 57.871  73.899  109.576 1.00 91.43  ? 518  G   D "C4'" 1 
ATOM   1941  O  "O4'" . G   B 1 17  ? 57.114  74.701  110.517 1.00 96.05  ? 518  G   D "O4'" 1 
ATOM   1942  C  "C3'" . G   B 1 17  ? 56.830  73.275  108.661 1.00 96.64  ? 518  G   D "C3'" 1 
ATOM   1943  O  "O3'" . G   B 1 17  ? 56.855  71.875  108.358 1.00 98.45  ? 518  G   D "O3'" 1 
ATOM   1944  C  "C2'" . G   B 1 17  ? 55.566  74.120  108.756 1.00 96.91  ? 518  G   D "C2'" 1 
ATOM   1945  O  "O2'" . G   B 1 17  ? 54.367  73.376  108.808 1.00 101.53 ? 518  G   D "O2'" 1 
ATOM   1946  C  "C1'" . G   B 1 17  ? 55.768  74.840  110.088 1.00 96.39  ? 518  G   D "C1'" 1 
ATOM   1947  N  N9    . G   B 1 17  ? 55.420  76.256  110.050 1.00 91.35  ? 518  G   D N9    1 
ATOM   1948  C  C8    . G   B 1 17  ? 55.602  77.140  109.015 1.00 88.88  ? 518  G   D C8    1 
ATOM   1949  N  N7    . G   B 1 17  ? 55.128  78.327  109.270 1.00 89.01  ? 518  G   D N7    1 
ATOM   1950  C  C5    . G   B 1 17  ? 54.612  78.220  110.554 1.00 96.24  ? 518  G   D C5    1 
ATOM   1951  C  C6    . G   B 1 17  ? 53.952  79.178  111.368 1.00 100.92 ? 518  G   D C6    1 
ATOM   1952  O  O6    . G   B 1 17  ? 53.664  80.349  111.103 1.00 108.55 ? 518  G   D O6    1 
ATOM   1953  N  N1    . G   B 1 17  ? 53.608  78.649  112.606 1.00 98.54  ? 518  G   D N1    1 
ATOM   1954  C  C2    . G   B 1 17  ? 53.850  77.360  113.007 1.00 95.86  ? 518  G   D C2    1 
ATOM   1955  N  N2    . G   B 1 17  ? 53.440  77.033  114.241 1.00 99.14  ? 518  G   D N2    1 
ATOM   1956  N  N3    . G   B 1 17  ? 54.450  76.457  112.257 1.00 94.10  ? 518  G   D N3    1 
ATOM   1957  C  C4    . G   B 1 17  ? 54.802  76.953  111.052 1.00 93.98  ? 518  G   D C4    1 
ATOM   1958  P  P     . G   B 1 18  ? 56.856  70.774  109.543 1.00 94.84  ? 519  G   D P     1 
ATOM   1959  O  OP1   . G   B 1 18  ? 57.972  71.058  110.483 1.00 95.46  ? 519  G   D OP1   1 
ATOM   1960  O  OP2   . G   B 1 18  ? 56.786  69.462  108.847 1.00 98.13  ? 519  G   D OP2   1 
ATOM   1961  O  "O5'" . G   B 1 18  ? 55.493  70.947  110.353 1.00 100.89 ? 519  G   D "O5'" 1 
ATOM   1962  C  "C5'" . G   B 1 18  ? 55.465  70.774  111.778 1.00 91.70  ? 519  G   D "C5'" 1 
ATOM   1963  C  "C4'" . G   B 1 18  ? 54.504  69.663  112.182 1.00 92.78  ? 519  G   D "C4'" 1 
ATOM   1964  O  "O4'" . G   B 1 18  ? 53.137  70.033  111.859 1.00 95.83  ? 519  G   D "O4'" 1 
ATOM   1965  C  "C3'" . G   B 1 18  ? 54.723  68.342  111.464 1.00 92.80  ? 519  G   D "C3'" 1 
ATOM   1966  O  "O3'" . G   B 1 18  ? 55.099  67.225  112.271 1.00 93.33  ? 519  G   D "O3'" 1 
ATOM   1967  C  "C2'" . G   B 1 18  ? 53.714  68.268  110.319 1.00 89.93  ? 519  G   D "C2'" 1 
ATOM   1968  O  "O2'" . G   B 1 18  ? 53.123  66.994  110.165 1.00 84.24  ? 519  G   D "O2'" 1 
ATOM   1969  C  "C1'" . G   B 1 18  ? 52.638  69.248  110.786 1.00 89.16  ? 519  G   D "C1'" 1 
ATOM   1970  N  N9    . G   B 1 18  ? 52.114  70.154  109.770 1.00 98.45  ? 519  G   D N9    1 
ATOM   1971  C  C8    . G   B 1 18  ? 52.550  70.325  108.476 1.00 101.29 ? 519  G   D C8    1 
ATOM   1972  N  N7    . G   B 1 18  ? 51.879  71.242  107.827 1.00 105.48 ? 519  G   D N7    1 
ATOM   1973  C  C5    . G   B 1 18  ? 50.941  71.699  108.747 1.00 103.66 ? 519  G   D C5    1 
ATOM   1974  C  C6    . G   B 1 18  ? 49.936  72.705  108.628 1.00 99.74  ? 519  G   D C6    1 
ATOM   1975  O  O6    . G   B 1 18  ? 49.672  73.422  107.656 1.00 93.56  ? 519  G   D O6    1 
ATOM   1976  N  N1    . G   B 1 18  ? 49.204  72.838  109.804 1.00 101.83 ? 519  G   D N1    1 
ATOM   1977  C  C2    . G   B 1 18  ? 49.408  72.108  110.952 1.00 104.73 ? 519  G   D C2    1 
ATOM   1978  N  N2    . G   B 1 18  ? 48.594  72.379  111.989 1.00 102.71 ? 519  G   D N2    1 
ATOM   1979  N  N3    . G   B 1 18  ? 50.340  71.178  111.077 1.00 107.71 ? 519  G   D N3    1 
ATOM   1980  C  C4    . G   B 1 18  ? 51.065  71.028  109.945 1.00 104.16 ? 519  G   D C4    1 
ATOM   1981  P  P     . U   B 1 19  ? 53.982  66.408  113.095 1.00 84.68  ? 520  U   D P     1 
ATOM   1982  O  OP1   . U   B 1 19  ? 52.632  66.698  112.554 1.00 91.18  ? 520  U   D OP1   1 
ATOM   1983  O  OP2   . U   B 1 19  ? 54.259  66.617  114.543 1.00 67.64  ? 520  U   D OP2   1 
ATOM   1984  O  "O5'" . U   B 1 19  ? 54.318  64.893  112.773 1.00 80.68  ? 520  U   D "O5'" 1 
ATOM   1985  C  "C5'" . U   B 1 19  ? 54.545  64.459  111.439 1.00 79.95  ? 520  U   D "C5'" 1 
ATOM   1986  C  "C4'" . U   B 1 19  ? 55.688  63.473  111.413 1.00 79.53  ? 520  U   D "C4'" 1 
ATOM   1987  O  "O4'" . U   B 1 19  ? 56.955  64.163  111.397 1.00 71.99  ? 520  U   D "O4'" 1 
ATOM   1988  C  "C3'" . U   B 1 19  ? 55.753  62.560  112.627 1.00 76.37  ? 520  U   D "C3'" 1 
ATOM   1989  O  "O3'" . U   B 1 19  ? 54.910  61.442  112.382 1.00 83.47  ? 520  U   D "O3'" 1 
ATOM   1990  C  "C2'" . U   B 1 19  ? 57.225  62.149  112.673 1.00 72.72  ? 520  U   D "C2'" 1 
ATOM   1991  O  "O2'" . U   B 1 19  ? 57.477  60.964  111.934 1.00 66.82  ? 520  U   D "O2'" 1 
ATOM   1992  C  "C1'" . U   B 1 19  ? 57.926  63.367  112.042 1.00 68.52  ? 520  U   D "C1'" 1 
ATOM   1993  N  N1    . U   B 1 19  ? 58.646  64.229  112.984 1.00 67.94  ? 520  U   D N1    1 
ATOM   1994  C  C2    . U   B 1 19  ? 60.001  64.411  112.771 1.00 68.69  ? 520  U   D C2    1 
ATOM   1995  O  O2    . U   B 1 19  ? 60.604  63.885  111.844 1.00 70.18  ? 520  U   D O2    1 
ATOM   1996  N  N3    . U   B 1 19  ? 60.624  65.234  113.679 1.00 60.27  ? 520  U   D N3    1 
ATOM   1997  C  C4    . U   B 1 19  ? 60.041  65.876  114.757 1.00 62.78  ? 520  U   D C4    1 
ATOM   1998  O  O4    . U   B 1 19  ? 60.734  66.590  115.492 1.00 41.98  ? 520  U   D O4    1 
ATOM   1999  C  C5    . U   B 1 19  ? 58.635  65.629  114.906 1.00 60.71  ? 520  U   D C5    1 
ATOM   2000  C  C6    . U   B 1 19  ? 58.004  64.833  114.033 1.00 63.24  ? 520  U   D C6    1 
ATOM   2001  P  P     . U   B 1 20  A 53.717  61.090  113.398 1.00 84.90  ? 520  U   D P     1 
ATOM   2002  O  OP1   . U   B 1 20  A 52.762  60.269  112.612 1.00 76.94  ? 520  U   D OP1   1 
ATOM   2003  O  OP2   . U   B 1 20  A 53.247  62.328  114.075 1.00 86.92  ? 520  U   D OP2   1 
ATOM   2004  O  "O5'" . U   B 1 20  A 54.418  60.172  114.492 1.00 71.79  ? 520  U   D "O5'" 1 
ATOM   2005  C  "C5'" . U   B 1 20  A 54.086  60.274  115.866 1.00 59.82  ? 520  U   D "C5'" 1 
ATOM   2006  C  "C4'" . U   B 1 20  A 55.007  59.390  116.667 1.00 60.77  ? 520  U   D "C4'" 1 
ATOM   2007  O  "O4'" . U   B 1 20  A 54.974  58.054  116.093 1.00 61.91  ? 520  U   D "O4'" 1 
ATOM   2008  C  "C3'" . U   B 1 20  A 56.469  59.783  116.590 1.00 61.46  ? 520  U   D "C3'" 1 
ATOM   2009  O  "O3'" . U   B 1 20  A 56.756  60.774  117.581 1.00 68.64  ? 520  U   D "O3'" 1 
ATOM   2010  C  "C2'" . U   B 1 20  A 57.167  58.463  116.883 1.00 57.36  ? 520  U   D "C2'" 1 
ATOM   2011  O  "O2'" . U   B 1 20  A 57.116  58.188  118.267 1.00 57.25  ? 520  U   D "O2'" 1 
ATOM   2012  C  "C1'" . U   B 1 20  A 56.263  57.464  116.153 1.00 56.86  ? 520  U   D "C1'" 1 
ATOM   2013  N  N1    . U   B 1 20  A 56.651  57.034  114.790 1.00 45.88  ? 520  U   D N1    1 
ATOM   2014  C  C2    . U   B 1 20  A 57.495  55.926  114.662 1.00 42.24  ? 520  U   D C2    1 
ATOM   2015  O  O2    . U   B 1 20  A 57.935  55.319  115.619 1.00 38.76  ? 520  U   D O2    1 
ATOM   2016  N  N3    . U   B 1 20  A 57.786  55.551  113.368 1.00 31.18  ? 520  U   D N3    1 
ATOM   2017  C  C4    . U   B 1 20  A 57.320  56.149  112.204 1.00 46.83  ? 520  U   D C4    1 
ATOM   2018  O  O4    . U   B 1 20  A 57.580  55.638  111.107 1.00 44.06  ? 520  U   D O4    1 
ATOM   2019  C  C5    . U   B 1 20  A 56.469  57.288  112.420 1.00 36.97  ? 520  U   D C5    1 
ATOM   2020  C  C6    . U   B 1 20  A 56.178  57.683  113.671 1.00 42.02  ? 520  U   D C6    1 
ATOM   2021  P  P     . A   B 1 21  ? 57.510  62.133  117.156 1.00 62.56  ? 521  A   D P     1 
ATOM   2022  O  OP1   . A   B 1 21  ? 57.450  63.088  118.291 1.00 54.78  ? 521  A   D OP1   1 
ATOM   2023  O  OP2   . A   B 1 21  ? 56.957  62.519  115.817 1.00 54.88  ? 521  A   D OP2   1 
ATOM   2024  O  "O5'" . A   B 1 21  ? 59.037  61.696  116.966 1.00 71.24  ? 521  A   D "O5'" 1 
ATOM   2025  C  "C5'" . A   B 1 21  ? 59.548  61.367  115.673 1.00 61.69  ? 521  A   D "C5'" 1 
ATOM   2026  C  "C4'" . A   B 1 21  ? 60.861  62.082  115.418 1.00 63.34  ? 521  A   D "C4'" 1 
ATOM   2027  O  "O4'" . A   B 1 21  ? 60.809  63.419  116.002 1.00 50.03  ? 521  A   D "O4'" 1 
ATOM   2028  C  "C3'" . A   B 1 21  ? 62.127  61.506  116.041 1.00 52.21  ? 521  A   D "C3'" 1 
ATOM   2029  O  "O3'" . A   B 1 21  ? 62.634  60.408  115.285 1.00 55.55  ? 521  A   D "O3'" 1 
ATOM   2030  C  "C2'" . A   B 1 21  ? 63.064  62.699  115.920 1.00 52.49  ? 521  A   D "C2'" 1 
ATOM   2031  O  "O2'" . A   B 1 21  ? 63.476  62.903  114.576 1.00 37.95  ? 521  A   D "O2'" 1 
ATOM   2032  C  "C1'" . A   B 1 21  ? 62.128  63.841  116.320 1.00 50.20  ? 521  A   D "C1'" 1 
ATOM   2033  N  N9    . A   B 1 21  ? 62.194  64.146  117.745 1.00 39.86  ? 521  A   D N9    1 
ATOM   2034  C  C8    . A   B 1 21  ? 61.269  63.871  118.709 1.00 42.20  ? 521  A   D C8    1 
ATOM   2035  N  N7    . A   B 1 21  ? 61.623  64.264  119.909 1.00 37.86  ? 521  A   D N7    1 
ATOM   2036  C  C5    . A   B 1 21  ? 62.860  64.849  119.717 1.00 44.71  ? 521  A   D C5    1 
ATOM   2037  C  C6    . A   B 1 21  ? 63.766  65.467  120.605 1.00 58.69  ? 521  A   D C6    1 
ATOM   2038  N  N6    . A   B 1 21  ? 63.538  65.615  121.924 1.00 52.89  ? 521  A   D N6    1 
ATOM   2039  N  N1    . A   B 1 21  ? 64.929  65.935  120.087 1.00 44.21  ? 521  A   D N1    1 
ATOM   2040  C  C2    . A   B 1 21  ? 65.148  65.790  118.775 1.00 42.81  ? 521  A   D C2    1 
ATOM   2041  N  N3    . A   B 1 21  ? 64.375  65.236  117.847 1.00 46.75  ? 521  A   D N3    1 
ATOM   2042  C  C4    . A   B 1 21  ? 63.230  64.778  118.390 1.00 45.36  ? 521  A   D C4    1 
ATOM   2043  P  P     . G   B 1 22  ? 62.872  58.980  116.003 1.00 53.87  ? 522  G   D P     1 
ATOM   2044  O  OP1   . G   B 1 22  ? 61.581  58.226  115.943 1.00 58.96  ? 522  G   D OP1   1 
ATOM   2045  O  OP2   . G   B 1 22  ? 63.550  59.167  117.321 1.00 37.34  ? 522  G   D OP2   1 
ATOM   2046  O  "O5'" . G   B 1 22  ? 63.878  58.265  115.010 1.00 47.90  ? 522  G   D "O5'" 1 
ATOM   2047  C  "C5'" . G   B 1 22  ? 63.462  57.923  113.700 1.00 45.37  ? 522  G   D "C5'" 1 
ATOM   2048  C  "C4'" . G   B 1 22  ? 64.582  58.170  112.720 1.00 55.52  ? 522  G   D "C4'" 1 
ATOM   2049  O  "O4'" . G   B 1 22  ? 64.741  59.604  112.512 1.00 57.01  ? 522  G   D "O4'" 1 
ATOM   2050  C  "C3'" . G   B 1 22  ? 65.969  57.725  113.168 1.00 47.88  ? 522  G   D "C3'" 1 
ATOM   2051  O  "O3'" . G   B 1 22  ? 66.178  56.325  113.053 1.00 42.95  ? 522  G   D "O3'" 1 
ATOM   2052  C  "C2'" . G   B 1 22  ? 66.848  58.560  112.253 1.00 52.97  ? 522  G   D "C2'" 1 
ATOM   2053  O  "O2'" . G   B 1 22  ? 66.878  58.082  110.911 1.00 52.36  ? 522  G   D "O2'" 1 
ATOM   2054  C  "C1'" . G   B 1 22  ? 66.118  59.907  112.334 1.00 50.70  ? 522  G   D "C1'" 1 
ATOM   2055  N  N9    . G   B 1 22  ? 66.571  60.671  113.494 1.00 47.92  ? 522  G   D N9    1 
ATOM   2056  C  C8    . G   B 1 22  ? 65.913  60.876  114.688 1.00 37.94  ? 522  G   D C8    1 
ATOM   2057  N  N7    . G   B 1 22  ? 66.614  61.566  115.549 1.00 38.34  ? 522  G   D N7    1 
ATOM   2058  C  C5    . G   B 1 22  ? 67.802  61.842  114.878 1.00 45.91  ? 522  G   D C5    1 
ATOM   2059  C  C6    . G   B 1 22  ? 68.978  62.543  115.303 1.00 44.41  ? 522  G   D C6    1 
ATOM   2060  O  O6    . G   B 1 22  ? 69.225  63.075  116.413 1.00 37.49  ? 522  G   D O6    1 
ATOM   2061  N  N1    . G   B 1 22  ? 69.931  62.579  114.292 1.00 39.82  ? 522  G   D N1    1 
ATOM   2062  C  C2    . G   B 1 22  ? 69.793  62.012  113.046 1.00 44.96  ? 522  G   D C2    1 
ATOM   2063  N  N2    . G   B 1 22  ? 70.820  62.156  112.196 1.00 38.91  ? 522  G   D N2    1 
ATOM   2064  N  N3    . G   B 1 22  ? 68.727  61.351  112.654 1.00 46.33  ? 522  G   D N3    1 
ATOM   2065  C  C4    . G   B 1 22  ? 67.780  61.306  113.606 1.00 46.37  ? 522  G   D C4    1 
ATOM   2066  P  P     . G   B 1 23  ? 67.159  55.592  114.096 1.00 55.78  ? 523  G   D P     1 
ATOM   2067  O  OP1   . G   B 1 23  ? 66.873  54.134  114.048 1.00 56.95  ? 523  G   D OP1   1 
ATOM   2068  O  OP2   . G   B 1 23  ? 67.128  56.295  115.402 1.00 44.52  ? 523  G   D OP2   1 
ATOM   2069  O  "O5'" . G   B 1 23  ? 68.595  55.876  113.460 1.00 47.61  ? 523  G   D "O5'" 1 
ATOM   2070  C  "C5'" . G   B 1 23  ? 68.810  55.718  112.059 1.00 33.31  ? 523  G   D "C5'" 1 
ATOM   2071  C  "C4'" . G   B 1 23  ? 70.140  56.294  111.666 1.00 29.94  ? 523  G   D "C4'" 1 
ATOM   2072  O  "O4'" . G   B 1 23  ? 70.095  57.740  111.804 1.00 33.58  ? 523  G   D "O4'" 1 
ATOM   2073  C  "C3'" . G   B 1 23  ? 71.330  55.886  112.527 1.00 37.25  ? 523  G   D "C3'" 1 
ATOM   2074  O  "O3'" . G   B 1 23  ? 71.861  54.615  112.132 1.00 38.81  ? 523  G   D "O3'" 1 
ATOM   2075  C  "C2'" . G   B 1 23  ? 72.314  56.997  112.207 1.00 29.84  ? 523  G   D "C2'" 1 
ATOM   2076  O  "O2'" . G   B 1 23  ? 72.856  56.772  110.919 1.00 45.06  ? 523  G   D "O2'" 1 
ATOM   2077  C  "C1'" . G   B 1 23  ? 71.388  58.220  112.144 1.00 39.87  ? 523  G   D "C1'" 1 
ATOM   2078  N  N9    . G   B 1 23  ? 71.291  58.897  113.427 1.00 42.40  ? 523  G   D N9    1 
ATOM   2079  C  C8    . G   B 1 23  ? 70.242  58.831  114.306 1.00 45.35  ? 523  G   D C8    1 
ATOM   2080  N  N7    . G   B 1 23  ? 70.452  59.498  115.406 1.00 36.54  ? 523  G   D N7    1 
ATOM   2081  C  C5    . G   B 1 23  ? 71.709  60.052  115.239 1.00 35.59  ? 523  G   D C5    1 
ATOM   2082  C  C6    . G   B 1 23  ? 72.461  60.883  116.101 1.00 47.02  ? 523  G   D C6    1 
ATOM   2083  O  O6    . G   B 1 23  ? 72.148  61.333  117.206 1.00 50.72  ? 523  G   D O6    1 
ATOM   2084  N  N1    . G   B 1 23  ? 73.698  61.199  115.558 1.00 51.72  ? 523  G   D N1    1 
ATOM   2085  C  C2    . G   B 1 23  ? 74.150  60.790  114.330 1.00 53.37  ? 523  G   D C2    1 
ATOM   2086  N  N2    . G   B 1 23  ? 75.394  61.201  114.006 1.00 42.40  ? 523  G   D N2    1 
ATOM   2087  N  N3    . G   B 1 23  ? 73.443  60.034  113.492 1.00 41.12  ? 523  G   D N3    1 
ATOM   2088  C  C4    . G   B 1 23  ? 72.242  59.698  114.017 1.00 48.05  ? 523  G   D C4    1 
ATOM   2089  P  P     . A   B 1 24  ? 72.646  53.703  113.211 1.00 45.75  ? 524  A   D P     1 
ATOM   2090  O  OP1   . A   B 1 24  ? 72.991  52.423  112.516 1.00 51.52  ? 524  A   D OP1   1 
ATOM   2091  O  OP2   . A   B 1 24  ? 71.870  53.673  114.488 1.00 44.25  ? 524  A   D OP2   1 
ATOM   2092  O  "O5'" . A   B 1 24  ? 73.999  54.484  113.539 1.00 38.95  ? 524  A   D "O5'" 1 
ATOM   2093  C  "C5'" . A   B 1 24  ? 75.043  54.579  112.573 1.00 29.75  ? 524  A   D "C5'" 1 
ATOM   2094  C  "C4'" . A   B 1 24  ? 76.185  55.399  113.116 1.00 33.93  ? 524  A   D "C4'" 1 
ATOM   2095  O  "O4'" . A   B 1 24  ? 75.767  56.781  113.288 1.00 39.00  ? 524  A   D "O4'" 1 
ATOM   2096  C  "C3'" . A   B 1 24  ? 76.722  55.000  114.484 1.00 36.33  ? 524  A   D "C3'" 1 
ATOM   2097  O  "O3'" . A   B 1 24  ? 77.636  53.900  114.393 1.00 34.08  ? 524  A   D "O3'" 1 
ATOM   2098  C  "C2'" . A   B 1 24  ? 77.411  56.289  114.921 1.00 36.48  ? 524  A   D "C2'" 1 
ATOM   2099  O  "O2'" . A   B 1 24  ? 78.666  56.482  114.279 1.00 39.31  ? 524  A   D "O2'" 1 
ATOM   2100  C  "C1'" . A   B 1 24  ? 76.415  57.343  114.421 1.00 37.09  ? 524  A   D "C1'" 1 
ATOM   2101  N  N9    . A   B 1 24  ? 75.395  57.674  115.426 1.00 40.14  ? 524  A   D N9    1 
ATOM   2102  C  C8    . A   B 1 24  ? 74.069  57.279  115.469 1.00 34.50  ? 524  A   D C8    1 
ATOM   2103  N  N7    . A   B 1 24  ? 73.428  57.694  116.533 1.00 34.89  ? 524  A   D N7    1 
ATOM   2104  C  C5    . A   B 1 24  ? 74.381  58.434  117.226 1.00 35.70  ? 524  A   D C5    1 
ATOM   2105  C  C6    . A   B 1 24  ? 74.326  59.141  118.437 1.00 40.41  ? 524  A   D C6    1 
ATOM   2106  N  N6    . A   B 1 24  ? 73.218  59.245  119.191 1.00 39.41  ? 524  A   D N6    1 
ATOM   2107  N  N1    . A   B 1 24  ? 75.459  59.749  118.857 1.00 36.77  ? 524  A   D N1    1 
ATOM   2108  C  C2    . A   B 1 24  ? 76.562  59.657  118.099 1.00 35.90  ? 524  A   D C2    1 
ATOM   2109  N  N3    . A   B 1 24  ? 76.736  59.032  116.941 1.00 34.48  ? 524  A   D N3    1 
ATOM   2110  C  C4    . A   B 1 24  ? 75.594  58.431  116.555 1.00 35.02  ? 524  A   D C4    1 
ATOM   2111  P  P     . C   B 1 25  ? 77.880  52.959  115.678 1.00 38.36  ? 525  C   D P     1 
ATOM   2112  O  OP1   . C   B 1 25  ? 78.714  51.793  115.257 1.00 40.77  ? 525  C   D OP1   1 
ATOM   2113  O  OP2   . C   B 1 25  ? 76.577  52.713  116.323 1.00 35.03  ? 525  C   D OP2   1 
ATOM   2114  O  "O5'" . C   B 1 25  ? 78.739  53.874  116.662 1.00 38.09  ? 525  C   D "O5'" 1 
ATOM   2115  C  "C5'" . C   B 1 25  ? 80.065  54.266  116.316 1.00 38.14  ? 525  C   D "C5'" 1 
ATOM   2116  C  "C4'" . C   B 1 25  ? 80.671  55.095  117.421 1.00 39.37  ? 525  C   D "C4'" 1 
ATOM   2117  O  "O4'" . C   B 1 25  ? 79.923  56.328  117.562 1.00 43.40  ? 525  C   D "O4'" 1 
ATOM   2118  C  "C3'" . C   B 1 25  ? 80.615  54.468  118.800 1.00 41.35  ? 525  C   D "C3'" 1 
ATOM   2119  O  "O3'" . C   B 1 25  ? 81.724  53.619  119.034 1.00 38.97  ? 525  C   D "O3'" 1 
ATOM   2120  C  "C2'" . C   B 1 25  ? 80.679  55.680  119.711 1.00 38.44  ? 525  C   D "C2'" 1 
ATOM   2121  O  "O2'" . C   B 1 25  ? 82.000  56.144  119.901 1.00 37.00  ? 525  C   D "O2'" 1 
ATOM   2122  C  "C1'" . C   B 1 25  ? 79.836  56.681  118.929 1.00 35.76  ? 525  C   D "C1'" 1 
ATOM   2123  N  N1    . C   B 1 25  ? 78.417  56.643  119.325 1.00 38.04  ? 525  C   D N1    1 
ATOM   2124  C  C2    . C   B 1 25  ? 78.070  57.215  120.523 1.00 30.05  ? 525  C   D C2    1 
ATOM   2125  O  O2    . C   B 1 25  ? 78.965  57.734  121.201 1.00 28.94  ? 525  C   D O2    1 
ATOM   2126  N  N3    . C   B 1 25  ? 76.776  57.194  120.929 1.00 33.01  ? 525  C   D N3    1 
ATOM   2127  C  C4    . C   B 1 25  ? 75.850  56.614  120.171 1.00 39.38  ? 525  C   D C4    1 
ATOM   2128  N  N4    . C   B 1 25  ? 74.593  56.585  120.635 1.00 32.43  ? 525  C   D N4    1 
ATOM   2129  C  C5    . C   B 1 25  ? 76.175  56.024  118.910 1.00 34.89  ? 525  C   D C5    1 
ATOM   2130  C  C6    . C   B 1 25  ? 77.463  56.059  118.533 1.00 41.39  ? 525  C   D C6    1 
ATOM   2131  P  P     . G   B 1 26  ? 81.532  52.310  119.921 1.00 40.33  ? 526  G   D P     1 
ATOM   2132  O  OP1   . G   B 1 26  ? 82.869  51.704  120.057 1.00 49.53  ? 526  G   D OP1   1 
ATOM   2133  O  OP2   . G   B 1 26  ? 80.422  51.539  119.330 1.00 33.96  ? 526  G   D OP2   1 
ATOM   2134  O  "O5'" . G   B 1 26  ? 81.060  52.848  121.339 1.00 40.44  ? 526  G   D "O5'" 1 
ATOM   2135  C  "C5'" . G   B 1 26  ? 81.959  53.534  122.183 1.00 36.80  ? 526  G   D "C5'" 1 
ATOM   2136  C  "C4'" . G   B 1 26  ? 81.242  54.010  123.410 1.00 47.09  ? 526  G   D "C4'" 1 
ATOM   2137  O  "O4'" . G   B 1 26  ? 80.270  55.029  123.036 1.00 49.30  ? 526  G   D "O4'" 1 
ATOM   2138  C  "C3'" . G   B 1 26  ? 80.401  52.968  124.135 1.00 45.40  ? 526  G   D "C3'" 1 
ATOM   2139  O  "O3'" . G   B 1 26  ? 81.196  52.173  125.005 1.00 47.94  ? 526  G   D "O3'" 1 
ATOM   2140  C  "C2'" . G   B 1 26  ? 79.466  53.866  124.928 1.00 41.87  ? 526  G   D "C2'" 1 
ATOM   2141  O  "O2'" . G   B 1 26  ? 80.166  54.525  125.958 1.00 39.06  ? 526  G   D "O2'" 1 
ATOM   2142  C  "C1'" . G   B 1 26  ? 79.126  54.917  123.878 1.00 38.63  ? 526  G   D "C1'" 1 
ATOM   2143  N  N9    . G   B 1 26  ? 77.980  54.517  123.067 1.00 33.56  ? 526  G   D N9    1 
ATOM   2144  C  C8    . G   B 1 26  ? 78.000  53.994  121.800 1.00 32.99  ? 526  G   D C8    1 
ATOM   2145  N  N7    . G   B 1 26  ? 76.806  53.766  121.322 1.00 37.17  ? 526  G   D N7    1 
ATOM   2146  C  C5    . G   B 1 26  ? 75.948  54.152  122.342 1.00 33.46  ? 526  G   D C5    1 
ATOM   2147  C  C6    . G   B 1 26  ? 74.525  54.145  122.402 1.00 36.54  ? 526  G   D C6    1 
ATOM   2148  O  O6    . G   B 1 26  ? 73.722  53.806  121.526 1.00 40.91  ? 526  G   D O6    1 
ATOM   2149  N  N1    . G   B 1 26  ? 74.059  54.605  123.633 1.00 34.32  ? 526  G   D N1    1 
ATOM   2150  C  C2    . G   B 1 26  ? 74.856  55.026  124.671 1.00 41.06  ? 526  G   D C2    1 
ATOM   2151  N  N2    . G   B 1 26  ? 74.224  55.398  125.792 1.00 36.23  ? 526  G   D N2    1 
ATOM   2152  N  N3    . G   B 1 26  ? 76.185  55.063  124.616 1.00 44.07  ? 526  G   D N3    1 
ATOM   2153  C  C4    . G   B 1 26  ? 76.658  54.609  123.429 1.00 31.74  ? 526  G   D C4    1 
ATOM   2154  P  P     . C   B 1 27  ? 80.731  50.673  125.359 1.00 43.28  ? 527  C   D P     1 
ATOM   2155  O  OP1   . C   B 1 27  ? 81.687  50.122  126.342 1.00 44.61  ? 527  C   D OP1   1 
ATOM   2156  O  OP2   . C   B 1 27  ? 80.480  49.951  124.090 1.00 52.04  ? 527  C   D OP2   1 
ATOM   2157  O  "O5'" . C   B 1 27  ? 79.328  50.859  126.095 1.00 60.86  ? 527  C   D "O5'" 1 
ATOM   2158  C  "C5'" . C   B 1 27  ? 79.267  51.385  127.425 1.00 51.35  ? 527  C   D "C5'" 1 
ATOM   2159  C  "C4'" . C   B 1 27  ? 77.840  51.373  127.941 1.00 54.90  ? 527  C   D "C4'" 1 
ATOM   2160  O  "O4'" . C   B 1 27  ? 77.005  52.298  127.188 1.00 43.39  ? 527  C   D "O4'" 1 
ATOM   2161  C  "C3'" . C   B 1 27  ? 77.096  50.054  127.826 1.00 56.49  ? 527  C   D "C3'" 1 
ATOM   2162  O  "O3'" . C   B 1 27  ? 77.487  49.185  128.874 1.00 63.15  ? 527  C   D "O3'" 1 
ATOM   2163  C  "C2'" . C   B 1 27  ? 75.645  50.507  127.948 1.00 53.93  ? 527  C   D "C2'" 1 
ATOM   2164  O  "O2'" . C   B 1 27  ? 75.268  50.807  129.287 1.00 52.69  ? 527  C   D "O2'" 1 
ATOM   2165  C  "C1'" . C   B 1 27  ? 75.677  51.792  127.113 1.00 46.50  ? 527  C   D "C1'" 1 
ATOM   2166  N  N1    . C   B 1 27  ? 75.369  51.520  125.703 1.00 40.52  ? 527  C   D N1    1 
ATOM   2167  C  C2    . C   B 1 27  ? 74.036  51.406  125.319 1.00 44.54  ? 527  C   D C2    1 
ATOM   2168  O  O2    . C   B 1 27  ? 73.154  51.572  126.173 1.00 47.16  ? 527  C   D O2    1 
ATOM   2169  N  N3    . C   B 1 27  ? 73.740  51.119  124.029 1.00 36.66  ? 527  C   D N3    1 
ATOM   2170  C  C4    . C   B 1 27  ? 74.725  50.953  123.141 1.00 41.12  ? 527  C   D C4    1 
ATOM   2171  N  N4    . C   B 1 27  ? 74.393  50.652  121.883 1.00 29.46  ? 527  C   D N4    1 
ATOM   2172  C  C5    . C   B 1 27  ? 76.096  51.082  123.506 1.00 30.97  ? 527  C   D C5    1 
ATOM   2173  C  C6    . C   B 1 27  ? 76.369  51.366  124.784 1.00 38.19  ? 527  C   D C6    1 
ATOM   2174  P  P     . G   B 1 28  ? 77.605  47.615  128.595 1.00 57.67  ? 528  G   D P     1 
ATOM   2175  O  OP1   . G   B 1 28  ? 78.362  47.084  129.754 1.00 51.35  ? 528  G   D OP1   1 
ATOM   2176  O  OP2   . G   B 1 28  ? 78.114  47.392  127.216 1.00 50.95  ? 528  G   D OP2   1 
ATOM   2177  O  "O5'" . G   B 1 28  ? 76.087  47.119  128.598 1.00 60.05  ? 528  G   D "O5'" 1 
ATOM   2178  C  "C5'" . G   B 1 28  ? 75.225  47.347  129.717 1.00 47.12  ? 528  G   D "C5'" 1 
ATOM   2179  C  "C4'" . G   B 1 28  ? 73.800  46.943  129.377 1.00 45.82  ? 528  G   D "C4'" 1 
ATOM   2180  O  "O4'" . G   B 1 28  ? 73.189  47.908  128.479 1.00 48.94  ? 528  G   D "O4'" 1 
ATOM   2181  C  "C3'" . G   B 1 28  ? 73.617  45.632  128.633 1.00 54.66  ? 528  G   D "C3'" 1 
ATOM   2182  O  "O3'" . G   B 1 28  ? 73.703  44.504  129.494 1.00 64.57  ? 528  G   D "O3'" 1 
ATOM   2183  C  "C2'" . G   B 1 28  ? 72.206  45.796  128.093 1.00 55.75  ? 528  G   D "C2'" 1 
ATOM   2184  O  "O2'" . G   B 1 28  ? 71.263  45.661  129.138 1.00 57.99  ? 528  G   D "O2'" 1 
ATOM   2185  C  "C1'" . G   B 1 28  ? 72.235  47.255  127.642 1.00 48.64  ? 528  G   D "C1'" 1 
ATOM   2186  N  N9    . G   B 1 28  ? 72.648  47.403  126.245 1.00 46.79  ? 528  G   D N9    1 
ATOM   2187  C  C8    . G   B 1 28  ? 73.893  47.783  125.791 1.00 43.96  ? 528  G   D C8    1 
ATOM   2188  N  N7    . G   B 1 28  ? 73.976  47.812  124.489 1.00 48.62  ? 528  G   D N7    1 
ATOM   2189  C  C5    . G   B 1 28  ? 72.709  47.440  124.049 1.00 35.79  ? 528  G   D C5    1 
ATOM   2190  C  C6    . G   B 1 28  ? 72.196  47.307  122.732 1.00 42.31  ? 528  G   D C6    1 
ATOM   2191  O  O6    . G   B 1 28  ? 72.767  47.514  121.660 1.00 51.30  ? 528  G   D O6    1 
ATOM   2192  N  N1    . G   B 1 28  ? 70.871  46.889  122.734 1.00 45.94  ? 528  G   D N1    1 
ATOM   2193  C  C2    . G   B 1 28  ? 70.135  46.635  123.851 1.00 41.64  ? 528  G   D C2    1 
ATOM   2194  N  N2    . G   B 1 28  ? 68.891  46.199  123.623 1.00 46.76  ? 528  G   D N2    1 
ATOM   2195  N  N3    . G   B 1 28  ? 70.589  46.784  125.094 1.00 38.82  ? 528  G   D N3    1 
ATOM   2196  C  C4    . G   B 1 28  ? 71.877  47.180  125.116 1.00 36.50  ? 528  G   D C4    1 
ATOM   2197  P  P     . G   B 1 29  ? 74.172  43.087  128.896 1.00 67.19  ? 529  G   D P     1 
ATOM   2198  O  OP1   . G   B 1 29  ? 74.364  42.163  130.040 1.00 68.55  ? 529  G   D OP1   1 
ATOM   2199  O  OP2   . G   B 1 29  ? 75.304  43.351  127.973 1.00 71.02  ? 529  G   D OP2   1 
ATOM   2200  O  "O5'" . G   B 1 29  ? 72.925  42.597  128.025 1.00 59.50  ? 529  G   D "O5'" 1 
ATOM   2201  C  "C5'" . G   B 1 29  ? 71.706  42.246  128.661 1.00 60.88  ? 529  G   D "C5'" 1 
ATOM   2202  C  "C4'" . G   B 1 29  ? 70.638  41.970  127.642 1.00 58.64  ? 529  G   D "C4'" 1 
ATOM   2203  O  "O4'" . G   B 1 29  ? 70.438  43.165  126.846 1.00 66.83  ? 529  G   D "O4'" 1 
ATOM   2204  C  "C3'" . G   B 1 29  ? 70.932  40.912  126.598 1.00 56.87  ? 529  G   D "C3'" 1 
ATOM   2205  O  "O3'" . G   B 1 29  ? 70.720  39.600  127.101 1.00 68.26  ? 529  G   D "O3'" 1 
ATOM   2206  C  "C2'" . G   B 1 29  ? 69.912  41.275  125.524 1.00 65.15  ? 529  G   D "C2'" 1 
ATOM   2207  O  "O2'" . G   B 1 29  ? 68.588  40.901  125.850 1.00 63.92  ? 529  G   D "O2'" 1 
ATOM   2208  C  "C1'" . G   B 1 29  ? 69.995  42.800  125.544 1.00 62.64  ? 529  G   D "C1'" 1 
ATOM   2209  N  N9    . G   B 1 29  ? 70.958  43.298  124.570 1.00 53.46  ? 529  G   D N9    1 
ATOM   2210  C  C8    . G   B 1 29  ? 72.201  43.823  124.830 1.00 49.39  ? 529  G   D C8    1 
ATOM   2211  N  N7    . G   B 1 29  ? 72.857  44.147  123.749 1.00 47.56  ? 529  G   D N7    1 
ATOM   2212  C  C5    . G   B 1 29  ? 71.988  43.831  122.708 1.00 43.46  ? 529  G   D C5    1 
ATOM   2213  C  C6    . G   B 1 29  ? 72.150  43.963  121.299 1.00 40.69  ? 529  G   D C6    1 
ATOM   2214  O  O6    . G   B 1 29  ? 73.112  44.403  120.669 1.00 48.74  ? 529  G   D O6    1 
ATOM   2215  N  N1    . G   B 1 29  ? 71.039  43.509  120.615 1.00 37.31  ? 529  G   D N1    1 
ATOM   2216  C  C2    . G   B 1 29  ? 69.910  42.986  121.198 1.00 43.70  ? 529  G   D C2    1 
ATOM   2217  N  N2    . G   B 1 29  ? 68.970  42.569  120.348 1.00 32.84  ? 529  G   D N2    1 
ATOM   2218  N  N3    . G   B 1 29  ? 69.730  42.873  122.508 1.00 36.67  ? 529  G   D N3    1 
ATOM   2219  C  C4    . G   B 1 29  ? 70.808  43.310  123.198 1.00 48.51  ? 529  G   D C4    1 
ATOM   2220  P  P     . C   B 1 30  ? 71.594  38.366  126.527 1.00 70.18  ? 530  C   D P     1 
ATOM   2221  O  OP1   . C   B 1 30  ? 71.293  37.187  127.381 1.00 68.24  ? 530  C   D OP1   1 
ATOM   2222  O  OP2   . C   B 1 30  ? 73.000  38.834  126.410 1.00 68.29  ? 530  C   D OP2   1 
ATOM   2223  O  "O5'" . C   B 1 30  ? 70.993  38.100  125.068 1.00 53.34  ? 530  C   D "O5'" 1 
ATOM   2224  C  "C5'" . C   B 1 30  ? 69.631  37.690  124.912 1.00 54.61  ? 530  C   D "C5'" 1 
ATOM   2225  C  "C4'" . C   B 1 30  ? 69.220  37.694  123.454 1.00 54.92  ? 530  C   D "C4'" 1 
ATOM   2226  O  "O4'" . C   B 1 30  ? 69.336  39.038  122.930 1.00 58.12  ? 530  C   D "O4'" 1 
ATOM   2227  C  "C3'" . C   B 1 30  ? 70.048  36.847  122.505 1.00 59.95  ? 530  C   D "C3'" 1 
ATOM   2228  O  "O3'" . C   B 1 30  ? 69.576  35.507  122.489 1.00 59.53  ? 530  C   D "O3'" 1 
ATOM   2229  C  "C2'" . C   B 1 30  ? 69.795  37.525  121.162 1.00 58.72  ? 530  C   D "C2'" 1 
ATOM   2230  O  "O2'" . C   B 1 30  ? 68.558  37.168  120.576 1.00 64.59  ? 530  C   D "O2'" 1 
ATOM   2231  C  "C1'" . C   B 1 30  ? 69.741  38.995  121.571 1.00 52.11  ? 530  C   D "C1'" 1 
ATOM   2232  N  N1    . C   B 1 30  ? 71.037  39.676  121.462 1.00 40.57  ? 530  C   D N1    1 
ATOM   2233  C  C2    . C   B 1 30  ? 71.500  40.050  120.196 1.00 42.82  ? 530  C   D C2    1 
ATOM   2234  O  O2    . C   B 1 30  ? 70.801  39.792  119.196 1.00 33.60  ? 530  C   D O2    1 
ATOM   2235  N  N3    . C   B 1 30  ? 72.693  40.684  120.093 1.00 38.76  ? 530  C   D N3    1 
ATOM   2236  C  C4    . C   B 1 30  ? 73.406  40.947  121.194 1.00 47.89  ? 530  C   D C4    1 
ATOM   2237  N  N4    . C   B 1 30  ? 74.569  41.597  121.055 1.00 39.54  ? 530  C   D N4    1 
ATOM   2238  C  C5    . C   B 1 30  ? 72.956  40.564  122.493 1.00 42.12  ? 530  C   D C5    1 
ATOM   2239  C  C6    . C   B 1 30  ? 71.779  39.940  122.577 1.00 40.06  ? 530  C   D C6    1 
ATOM   2240  P  P     . C   B 1 31  ? 70.583  34.308  122.122 1.00 68.55  ? 531  C   D P     1 
ATOM   2241  O  OP1   . C   B 1 31  ? 69.810  33.045  122.268 1.00 60.06  ? 531  C   D OP1   1 
ATOM   2242  O  OP2   . C   B 1 31  ? 71.818  34.527  122.947 1.00 50.81  ? 531  C   D OP2   1 
ATOM   2243  O  "O5'" . C   B 1 31  ? 70.892  34.488  120.563 1.00 49.08  ? 531  C   D "O5'" 1 
ATOM   2244  C  "C5'" . C   B 1 31  ? 69.877  34.233  119.608 1.00 47.98  ? 531  C   D "C5'" 1 
ATOM   2245  C  "C4'" . C   B 1 31  ? 70.320  34.644  118.230 1.00 47.52  ? 531  C   D "C4'" 1 
ATOM   2246  O  "O4'" . C   B 1 31  ? 70.705  36.040  118.254 1.00 49.80  ? 531  C   D "O4'" 1 
ATOM   2247  C  "C3'" . C   B 1 31  ? 71.549  33.952  117.679 1.00 47.69  ? 531  C   D "C3'" 1 
ATOM   2248  O  "O3'" . C   B 1 31  ? 71.213  32.688  117.118 1.00 59.38  ? 531  C   D "O3'" 1 
ATOM   2249  C  "C2'" . C   B 1 31  ? 71.998  34.928  116.597 1.00 50.17  ? 531  C   D "C2'" 1 
ATOM   2250  O  "O2'" . C   B 1 31  ? 71.277  34.795  115.383 1.00 41.06  ? 531  C   D "O2'" 1 
ATOM   2251  C  "C1'" . C   B 1 31  ? 71.686  36.273  117.256 1.00 43.57  ? 531  C   D "C1'" 1 
ATOM   2252  N  N1    . C   B 1 31  ? 72.846  36.908  117.895 1.00 44.12  ? 531  C   D N1    1 
ATOM   2253  C  C2    . C   B 1 31  ? 73.784  37.558  117.092 1.00 38.90  ? 531  C   D C2    1 
ATOM   2254  O  O2    . C   B 1 31  ? 73.628  37.546  115.860 1.00 37.99  ? 531  C   D O2    1 
ATOM   2255  N  N3    . C   B 1 31  ? 74.825  38.187  117.674 1.00 33.72  ? 531  C   D N3    1 
ATOM   2256  C  C4    . C   B 1 31  ? 74.940  38.202  119.008 1.00 42.19  ? 531  C   D C4    1 
ATOM   2257  N  N4    . C   B 1 31  ? 75.950  38.908  119.547 1.00 36.25  ? 531  C   D N4    1 
ATOM   2258  C  C5    . C   B 1 31  ? 74.018  37.519  119.850 1.00 34.61  ? 531  C   D C5    1 
ATOM   2259  C  C6    . C   B 1 31  ? 72.996  36.887  119.256 1.00 47.62  ? 531  C   D C6    1 
ATOM   2260  P  P     . C   B 1 32  ? 72.222  31.438  117.291 1.00 58.37  ? 532  C   D P     1 
ATOM   2261  O  OP1   . C   B 1 32  ? 71.600  30.251  116.656 1.00 64.76  ? 532  C   D OP1   1 
ATOM   2262  O  OP2   . C   B 1 32  ? 72.640  31.384  118.722 1.00 47.40  ? 532  C   D OP2   1 
ATOM   2263  O  "O5'" . C   B 1 32  ? 73.485  31.812  116.400 1.00 53.42  ? 532  C   D "O5'" 1 
ATOM   2264  C  "C5'" . C   B 1 32  ? 73.369  31.934  114.988 1.00 53.22  ? 532  C   D "C5'" 1 
ATOM   2265  C  "C4'" . C   B 1 32  ? 74.622  32.563  114.431 1.00 56.57  ? 532  C   D "C4'" 1 
ATOM   2266  O  "O4'" . C   B 1 32  ? 74.738  33.914  114.942 1.00 48.79  ? 532  C   D "O4'" 1 
ATOM   2267  C  "C3'" . C   B 1 32  ? 75.918  31.883  114.847 1.00 57.61  ? 532  C   D "C3'" 1 
ATOM   2268  O  "O3'" . C   B 1 32  ? 76.213  30.806  113.948 1.00 54.84  ? 532  C   D "O3'" 1 
ATOM   2269  C  "C2'" . C   B 1 32  ? 76.930  33.017  114.727 1.00 50.36  ? 532  C   D "C2'" 1 
ATOM   2270  O  "O2'" . C   B 1 32  ? 77.348  33.211  113.389 1.00 53.94  ? 532  C   D "O2'" 1 
ATOM   2271  C  "C1'" . C   B 1 32  ? 76.097  34.226  115.163 1.00 48.67  ? 532  C   D "C1'" 1 
ATOM   2272  N  N1    . C   B 1 32  ? 76.237  34.593  116.572 1.00 46.56  ? 532  C   D N1    1 
ATOM   2273  C  C2    . C   B 1 32  ? 77.349  35.363  116.979 1.00 45.57  ? 532  C   D C2    1 
ATOM   2274  O  O2    . C   B 1 32  ? 78.186  35.708  116.128 1.00 49.23  ? 532  C   D O2    1 
ATOM   2275  N  N3    . C   B 1 32  ? 77.473  35.705  118.284 1.00 40.23  ? 532  C   D N3    1 
ATOM   2276  C  C4    . C   B 1 32  ? 76.549  35.306  119.165 1.00 43.94  ? 532  C   D C4    1 
ATOM   2277  N  N4    . C   B 1 32  ? 76.709  35.649  120.441 1.00 39.50  ? 532  C   D N4    1 
ATOM   2278  C  C5    . C   B 1 32  ? 75.415  34.531  118.774 1.00 42.07  ? 532  C   D C5    1 
ATOM   2279  C  C6    . C   B 1 32  ? 75.300  34.201  117.481 1.00 41.52  ? 532  C   D C6    1 
ATOM   2280  P  P     . U   B 1 33  ? 76.308  29.301  114.506 1.00 64.33  ? 533  U   D P     1 
ATOM   2281  O  OP1   . U   B 1 33  ? 76.506  28.423  113.332 1.00 61.12  ? 533  U   D OP1   1 
ATOM   2282  O  OP2   . U   B 1 33  ? 75.179  29.029  115.439 1.00 55.30  ? 533  U   D OP2   1 
ATOM   2283  O  "O5'" . U   B 1 33  ? 77.640  29.315  115.385 1.00 56.01  ? 533  U   D "O5'" 1 
ATOM   2284  C  "C5'" . U   B 1 33  ? 78.914  29.417  114.765 1.00 60.78  ? 533  U   D "C5'" 1 
ATOM   2285  C  "C4'" . U   B 1 33  ? 79.934  29.899  115.760 1.00 60.18  ? 533  U   D "C4'" 1 
ATOM   2286  O  "O4'" . U   B 1 33  ? 79.476  31.171  116.284 1.00 51.75  ? 533  U   D "O4'" 1 
ATOM   2287  C  "C3'" . U   B 1 33  ? 80.136  29.026  116.991 1.00 62.49  ? 533  U   D "C3'" 1 
ATOM   2288  O  "O3'" . U   B 1 33  ? 81.079  27.969  116.728 1.00 56.31  ? 533  U   D "O3'" 1 
ATOM   2289  C  "C2'" . U   B 1 33  ? 80.656  30.036  118.011 1.00 60.86  ? 533  U   D "C2'" 1 
ATOM   2290  O  "O2'" . U   B 1 33  ? 82.045  30.270  117.891 1.00 68.99  ? 533  U   D "O2'" 1 
ATOM   2291  C  "C1'" . U   B 1 33  ? 79.867  31.301  117.638 1.00 58.31  ? 533  U   D "C1'" 1 
ATOM   2292  N  N1    . U   B 1 33  ? 78.655  31.478  118.455 1.00 63.79  ? 533  U   D N1    1 
ATOM   2293  C  C2    . U   B 1 33  ? 78.742  32.289  119.577 1.00 56.11  ? 533  U   D C2    1 
ATOM   2294  O  O2    . U   B 1 33  ? 79.740  32.904  119.873 1.00 41.48  ? 533  U   D O2    1 
ATOM   2295  N  N3    . U   B 1 33  ? 77.605  32.347  120.343 1.00 68.77  ? 533  U   D N3    1 
ATOM   2296  C  C4    . U   B 1 33  ? 76.410  31.696  120.109 1.00 73.13  ? 533  U   D C4    1 
ATOM   2297  O  O4    . U   B 1 33  ? 75.518  31.751  120.962 1.00 72.80  ? 533  U   D O4    1 
ATOM   2298  C  C5    . U   B 1 33  ? 76.382  30.909  118.902 1.00 71.69  ? 533  U   D C5    1 
ATOM   2299  C  C6    . U   B 1 33  ? 77.476  30.832  118.136 1.00 68.59  ? 533  U   D C6    1 
ATOM   2300  P  P     . C   B 1 34  ? 81.100  26.642  117.664 1.00 58.91  ? 534  C   D P     1 
ATOM   2301  O  OP1   . C   B 1 34  ? 81.689  25.535  116.877 1.00 56.08  ? 534  C   D OP1   1 
ATOM   2302  O  OP2   . C   B 1 34  ? 79.758  26.453  118.294 1.00 57.65  ? 534  C   D OP2   1 
ATOM   2303  O  "O5'" . C   B 1 34  ? 82.144  27.030  118.803 1.00 48.49  ? 534  C   D "O5'" 1 
ATOM   2304  C  "C5'" . C   B 1 34  ? 82.148  26.382  120.067 1.00 42.83  ? 534  C   D "C5'" 1 
ATOM   2305  C  "C4'" . C   B 1 34  ? 83.370  26.808  120.843 1.00 44.97  ? 534  C   D "C4'" 1 
ATOM   2306  O  "O4'" . C   B 1 34  ? 84.552  26.262  120.196 1.00 38.43  ? 534  C   D "O4'" 1 
ATOM   2307  C  "C3'" . C   B 1 34  ? 83.604  28.314  120.868 1.00 37.87  ? 534  C   D "C3'" 1 
ATOM   2308  O  "O3'" . C   B 1 34  ? 82.908  28.926  121.945 1.00 41.99  ? 534  C   D "O3'" 1 
ATOM   2309  C  "C2'" . C   B 1 34  ? 85.104  28.395  121.078 1.00 39.47  ? 534  C   D "C2'" 1 
ATOM   2310  O  "O2'" . C   B 1 34  ? 85.440  28.172  122.430 1.00 42.40  ? 534  C   D "O2'" 1 
ATOM   2311  C  "C1'" . C   B 1 34  ? 85.590  27.226  120.217 1.00 41.25  ? 534  C   D "C1'" 1 
ATOM   2312  N  N1    . C   B 1 34  ? 85.890  27.616  118.835 1.00 31.03  ? 534  C   D N1    1 
ATOM   2313  C  C2    . C   B 1 34  ? 87.107  28.234  118.581 1.00 36.92  ? 534  C   D C2    1 
ATOM   2314  O  O2    . C   B 1 34  ? 87.852  28.448  119.530 1.00 37.91  ? 534  C   D O2    1 
ATOM   2315  N  N3    . C   B 1 34  ? 87.437  28.587  117.310 1.00 26.35  ? 534  C   D N3    1 
ATOM   2316  C  C4    . C   B 1 34  ? 86.574  28.360  116.317 1.00 44.29  ? 534  C   D C4    1 
ATOM   2317  N  N4    . C   B 1 34  ? 86.926  28.740  115.074 1.00 35.69  ? 534  C   D N4    1 
ATOM   2318  C  C5    . C   B 1 34  ? 85.302  27.735  116.552 1.00 39.72  ? 534  C   D C5    1 
ATOM   2319  C  C6    . C   B 1 34  ? 85.009  27.382  117.817 1.00 32.00  ? 534  C   D C6    1 
ATOM   2320  P  P     . U   B 1 35  ? 82.328  30.424  121.784 1.00 44.85  ? 535  U   D P     1 
ATOM   2321  O  OP1   . U   B 1 35  ? 81.043  30.454  122.502 1.00 47.85  ? 535  U   D OP1   1 
ATOM   2322  O  OP2   . U   B 1 35  ? 82.382  30.835  120.357 1.00 32.54  ? 535  U   D OP2   1 
ATOM   2323  O  "O5'" . U   B 1 35  ? 83.340  31.322  122.611 1.00 33.56  ? 535  U   D "O5'" 1 
ATOM   2324  C  "C5'" . U   B 1 35  ? 83.619  31.021  123.961 1.00 34.60  ? 535  U   D "C5'" 1 
ATOM   2325  C  "C4'" . U   B 1 35  ? 84.842  31.772  124.399 1.00 34.16  ? 535  U   D "C4'" 1 
ATOM   2326  O  "O4'" . U   B 1 35  ? 85.956  31.351  123.569 1.00 30.35  ? 535  U   D "O4'" 1 
ATOM   2327  C  "C3'" . U   B 1 35  ? 84.772  33.268  124.159 1.00 33.10  ? 535  U   D "C3'" 1 
ATOM   2328  O  "O3'" . U   B 1 35  ? 84.123  33.919  125.239 1.00 37.36  ? 535  U   D "O3'" 1 
ATOM   2329  C  "C2'" . U   B 1 35  ? 86.243  33.634  124.124 1.00 30.31  ? 535  U   D "C2'" 1 
ATOM   2330  O  "O2'" . U   B 1 35  ? 86.765  33.670  125.436 1.00 30.02  ? 535  U   D "O2'" 1 
ATOM   2331  C  "C1'" . U   B 1 35  ? 86.827  32.443  123.356 1.00 32.18  ? 535  U   D "C1'" 1 
ATOM   2332  N  N1    . U   B 1 35  ? 86.937  32.651  121.902 1.00 29.65  ? 535  U   D N1    1 
ATOM   2333  C  C2    . U   B 1 35  ? 87.958  33.455  121.434 1.00 25.92  ? 535  U   D C2    1 
ATOM   2334  O  O2    . U   B 1 35  ? 88.744  34.046  122.177 1.00 27.24  ? 535  U   D O2    1 
ATOM   2335  N  N3    . U   B 1 35  ? 88.026  33.557  120.065 1.00 24.45  ? 535  U   D N3    1 
ATOM   2336  C  C4    . U   B 1 35  ? 87.201  32.960  119.142 1.00 27.82  ? 535  U   D C4    1 
ATOM   2337  O  O4    . U   B 1 35  ? 87.464  33.057  117.949 1.00 29.82  ? 535  U   D O4    1 
ATOM   2338  C  C5    . U   B 1 35  ? 86.151  32.174  119.702 1.00 29.94  ? 535  U   D C5    1 
ATOM   2339  C  C6    . U   B 1 35  ? 86.056  32.049  121.032 1.00 32.50  ? 535  U   D C6    1 
ATOM   2340  P  P     . C   B 1 36  ? 83.139  35.147  124.948 1.00 35.37  ? 536  C   D P     1 
ATOM   2341  O  OP1   . C   B 1 36  ? 82.503  35.532  126.219 1.00 39.56  ? 536  C   D OP1   1 
ATOM   2342  O  OP2   . C   B 1 36  ? 82.300  34.721  123.792 1.00 30.77  ? 536  C   D OP2   1 
ATOM   2343  O  "O5'" . C   B 1 36  ? 84.079  36.356  124.509 1.00 31.21  ? 536  C   D "O5'" 1 
ATOM   2344  C  "C5'" . C   B 1 36  ? 85.053  36.893  125.402 1.00 39.12  ? 536  C   D "C5'" 1 
ATOM   2345  C  "C4'" . C   B 1 36  ? 86.047  37.753  124.642 1.00 44.75  ? 536  C   D "C4'" 1 
ATOM   2346  O  "O4'" . C   B 1 36  ? 86.819  36.945  123.696 1.00 49.91  ? 536  C   D "O4'" 1 
ATOM   2347  C  "C3'" . C   B 1 36  ? 85.412  38.818  123.769 1.00 39.67  ? 536  C   D "C3'" 1 
ATOM   2348  O  "O3'" . C   B 1 36  ? 85.065  39.961  124.532 1.00 36.47  ? 536  C   D "O3'" 1 
ATOM   2349  C  "C2'" . C   B 1 36  ? 86.518  39.112  122.769 1.00 34.87  ? 536  C   D "C2'" 1 
ATOM   2350  O  "O2'" . C   B 1 36  ? 87.492  39.986  123.303 1.00 46.99  ? 536  C   D "O2'" 1 
ATOM   2351  C  "C1'" . C   B 1 36  ? 87.094  37.712  122.531 1.00 37.22  ? 536  C   D "C1'" 1 
ATOM   2352  N  N1    . C   B 1 36  ? 86.480  37.033  121.376 1.00 36.62  ? 536  C   D N1    1 
ATOM   2353  C  C2    . C   B 1 36  ? 87.055  37.194  120.108 1.00 31.41  ? 536  C   D C2    1 
ATOM   2354  O  O2    . C   B 1 36  ? 88.034  37.942  119.980 1.00 39.52  ? 536  C   D O2    1 
ATOM   2355  N  N3    . C   B 1 36  ? 86.524  36.539  119.052 1.00 28.87  ? 536  C   D N3    1 
ATOM   2356  C  C4    . C   B 1 36  ? 85.447  35.770  119.215 1.00 28.37  ? 536  C   D C4    1 
ATOM   2357  N  N4    . C   B 1 36  ? 84.961  35.145  118.139 1.00 22.10  ? 536  C   D N4    1 
ATOM   2358  C  C5    . C   B 1 36  ? 84.817  35.610  120.489 1.00 23.20  ? 536  C   D C5    1 
ATOM   2359  C  C6    . C   B 1 36  ? 85.365  36.249  121.532 1.00 34.80  ? 536  C   D C6    1 
ATOM   2360  P  P     . A   B 1 37  ? 83.993  41.006  123.951 1.00 42.05  ? 537  A   D P     1 
ATOM   2361  O  OP1   . A   B 1 37  ? 83.727  41.997  125.028 1.00 50.77  ? 537  A   D OP1   1 
ATOM   2362  O  OP2   . A   B 1 37  ? 82.857  40.286  123.302 1.00 27.95  ? 537  A   D OP2   1 
ATOM   2363  O  "O5'" . A   B 1 37  ? 84.780  41.755  122.795 1.00 37.82  ? 537  A   D "O5'" 1 
ATOM   2364  C  "C5'" . A   B 1 37  ? 84.151  42.052  121.559 1.00 25.46  ? 537  A   D "C5'" 1 
ATOM   2365  C  "C4'" . A   B 1 37  ? 85.200  42.177  120.483 1.00 43.72  ? 537  A   D "C4'" 1 
ATOM   2366  O  "O4'" . A   B 1 37  ? 85.776  40.865  120.203 1.00 40.37  ? 537  A   D "O4'" 1 
ATOM   2367  C  "C3'" . A   B 1 37  ? 84.698  42.654  119.132 1.00 40.17  ? 537  A   D "C3'" 1 
ATOM   2368  O  "O3'" . A   B 1 37  ? 84.606  44.074  119.140 1.00 33.14  ? 537  A   D "O3'" 1 
ATOM   2369  C  "C2'" . A   B 1 37  ? 85.799  42.141  118.215 1.00 39.80  ? 537  A   D "C2'" 1 
ATOM   2370  O  "O2'" . A   B 1 37  ? 86.994  42.897  118.368 1.00 33.99  ? 537  A   D "O2'" 1 
ATOM   2371  C  "C1'" . A   B 1 37  ? 86.045  40.749  118.808 1.00 38.64  ? 537  A   D "C1'" 1 
ATOM   2372  N  N9    . A   B 1 37  ? 85.166  39.719  118.243 1.00 37.15  ? 537  A   D N9    1 
ATOM   2373  C  C8    . A   B 1 37  ? 84.167  39.021  118.880 1.00 34.38  ? 537  A   D C8    1 
ATOM   2374  N  N7    . A   B 1 37  ? 83.530  38.178  118.102 1.00 34.40  ? 537  A   D N7    1 
ATOM   2375  C  C5    . A   B 1 37  ? 84.147  38.324  116.870 1.00 35.84  ? 537  A   D C5    1 
ATOM   2376  C  C6    . A   B 1 37  ? 83.932  37.712  115.611 1.00 33.62  ? 537  A   D C6    1 
ATOM   2377  N  N6    . A   B 1 37  ? 82.969  36.824  115.363 1.00 33.96  ? 537  A   D N6    1 
ATOM   2378  N  N1    . A   B 1 37  ? 84.749  38.068  114.593 1.00 32.72  ? 537  A   D N1    1 
ATOM   2379  C  C2    . A   B 1 37  ? 85.694  38.986  114.821 1.00 33.02  ? 537  A   D C2    1 
ATOM   2380  N  N3    . A   B 1 37  ? 85.982  39.641  115.946 1.00 43.03  ? 537  A   D N3    1 
ATOM   2381  C  C4    . A   B 1 37  ? 85.167  39.262  116.945 1.00 39.38  ? 537  A   D C4    1 
ATOM   2382  P  P     . A   B 1 38  ? 83.325  44.799  118.484 1.00 33.46  ? 538  A   D P     1 
ATOM   2383  O  OP1   . A   B 1 38  ? 83.575  46.253  118.579 1.00 28.05  ? 538  A   D OP1   1 
ATOM   2384  O  OP2   . A   B 1 38  ? 82.099  44.214  119.101 1.00 34.71  ? 538  A   D OP2   1 
ATOM   2385  O  "O5'" . A   B 1 38  ? 83.382  44.386  116.945 1.00 29.61  ? 538  A   D "O5'" 1 
ATOM   2386  C  "C5'" . A   B 1 38  ? 84.501  44.767  116.156 1.00 24.49  ? 538  A   D "C5'" 1 
ATOM   2387  C  "C4'" . A   B 1 38  ? 84.447  44.091  114.832 1.00 22.89  ? 538  A   D "C4'" 1 
ATOM   2388  O  "O4'" . A   B 1 38  ? 84.634  42.675  115.019 1.00 23.33  ? 538  A   D "O4'" 1 
ATOM   2389  C  "C3'" . A   B 1 38  ? 83.107  44.199  114.139 1.00 29.53  ? 538  A   D "C3'" 1 
ATOM   2390  O  "O3'" . A   B 1 38  ? 83.057  45.404  113.414 1.00 29.33  ? 538  A   D "O3'" 1 
ATOM   2391  C  "C2'" . A   B 1 38  ? 83.156  43.001  113.210 1.00 33.06  ? 538  A   D "C2'" 1 
ATOM   2392  O  "O2'" . A   B 1 38  ? 83.998  43.218  112.108 1.00 30.27  ? 538  A   D "O2'" 1 
ATOM   2393  C  "C1'" . A   B 1 38  ? 83.821  41.970  114.112 1.00 28.17  ? 538  A   D "C1'" 1 
ATOM   2394  N  N9    . A   B 1 38  ? 82.821  41.279  114.896 1.00 36.66  ? 538  A   D N9    1 
ATOM   2395  C  C8    . A   B 1 38  ? 82.493  41.499  116.215 1.00 40.74  ? 538  A   D C8    1 
ATOM   2396  N  N7    . A   B 1 38  ? 81.562  40.697  116.665 1.00 36.13  ? 538  A   D N7    1 
ATOM   2397  C  C5    . A   B 1 38  ? 81.254  39.899  115.568 1.00 38.26  ? 538  A   D C5    1 
ATOM   2398  C  C6    . A   B 1 38  ? 80.361  38.827  115.399 1.00 35.76  ? 538  A   D C6    1 
ATOM   2399  N  N6    . A   B 1 38  ? 79.588  38.348  116.371 1.00 27.17  ? 538  A   D N6    1 
ATOM   2400  N  N1    . A   B 1 38  ? 80.303  38.250  114.184 1.00 36.42  ? 538  A   D N1    1 
ATOM   2401  C  C2    . A   B 1 38  ? 81.102  38.716  113.210 1.00 36.73  ? 538  A   D C2    1 
ATOM   2402  N  N3    . A   B 1 38  ? 81.988  39.712  113.247 1.00 29.21  ? 538  A   D N3    1 
ATOM   2403  C  C4    . A   B 1 38  ? 82.016  40.261  114.469 1.00 32.62  ? 538  A   D C4    1 
ATOM   2404  P  P     . G   B 1 39  ? 81.684  46.232  113.314 1.00 32.36  ? 539  G   D P     1 
ATOM   2405  O  OP1   . G   B 1 39  ? 81.975  47.352  112.396 1.00 27.41  ? 539  G   D OP1   1 
ATOM   2406  O  OP2   . G   B 1 39  ? 81.176  46.514  114.684 1.00 37.18  ? 539  G   D OP2   1 
ATOM   2407  O  "O5'" . G   B 1 39  ? 80.665  45.229  112.610 1.00 29.80  ? 539  G   D "O5'" 1 
ATOM   2408  C  "C5'" . G   B 1 39  ? 80.843  44.829  111.259 1.00 40.61  ? 539  G   D "C5'" 1 
ATOM   2409  C  "C4'" . G   B 1 39  ? 79.846  43.745  110.893 1.00 39.58  ? 539  G   D "C4'" 1 
ATOM   2410  O  "O4'" . G   B 1 39  ? 80.127  42.538  111.650 1.00 40.33  ? 539  G   D "O4'" 1 
ATOM   2411  C  "C3'" . G   B 1 39  ? 78.393  44.024  111.228 1.00 42.46  ? 539  G   D "C3'" 1 
ATOM   2412  O  "O3'" . G   B 1 39  ? 77.767  44.859  110.264 1.00 49.40  ? 539  G   D "O3'" 1 
ATOM   2413  C  "C2'" . G   B 1 39  ? 77.813  42.624  111.189 1.00 40.39  ? 539  G   D "C2'" 1 
ATOM   2414  O  "O2'" . G   B 1 39  ? 77.679  42.194  109.844 1.00 34.18  ? 539  G   D "O2'" 1 
ATOM   2415  C  "C1'" . G   B 1 39  ? 78.919  41.837  111.900 1.00 39.61  ? 539  G   D "C1'" 1 
ATOM   2416  N  N9    . G   B 1 39  ? 78.725  41.770  113.346 1.00 36.76  ? 539  G   D N9    1 
ATOM   2417  C  C8    . G   B 1 39  ? 79.357  42.541  114.295 1.00 35.39  ? 539  G   D C8    1 
ATOM   2418  N  N7    . G   B 1 39  ? 78.974  42.271  115.515 1.00 30.91  ? 539  G   D N7    1 
ATOM   2419  C  C5    . G   B 1 39  ? 78.034  41.254  115.368 1.00 37.89  ? 539  G   D C5    1 
ATOM   2420  C  C6    . G   B 1 39  ? 77.272  40.540  116.353 1.00 37.30  ? 539  G   D C6    1 
ATOM   2421  O  O6    . G   B 1 39  ? 77.269  40.672  117.598 1.00 43.04  ? 539  G   D O6    1 
ATOM   2422  N  N1    . G   B 1 39  ? 76.446  39.593  115.766 1.00 41.05  ? 539  G   D N1    1 
ATOM   2423  C  C2    . G   B 1 39  ? 76.338  39.361  114.426 1.00 39.29  ? 539  G   D C2    1 
ATOM   2424  N  N2    . G   B 1 39  ? 75.460  38.416  114.084 1.00 34.97  ? 539  G   D N2    1 
ATOM   2425  N  N3    . G   B 1 39  ? 77.033  40.008  113.495 1.00 41.04  ? 539  G   D N3    1 
ATOM   2426  C  C4    . G   B 1 39  ? 77.861  40.934  114.037 1.00 41.38  ? 539  G   D C4    1 
ATOM   2427  P  P     . G   B 1 40  ? 76.567  45.833  110.719 1.00 59.55  ? 540  G   D P     1 
ATOM   2428  O  OP1   . G   B 1 40  ? 76.337  46.750  109.572 1.00 48.21  ? 540  G   D OP1   1 
ATOM   2429  O  OP2   . G   B 1 40  ? 76.902  46.395  112.064 1.00 35.90  ? 540  G   D OP2   1 
ATOM   2430  O  "O5'" . G   B 1 40  ? 75.310  44.863  110.926 1.00 51.84  ? 540  G   D "O5'" 1 
ATOM   2431  C  "C5'" . G   B 1 40  ? 74.830  44.030  109.875 1.00 50.00  ? 540  G   D "C5'" 1 
ATOM   2432  C  "C4'" . G   B 1 40  ? 73.765  43.075  110.395 1.00 60.00  ? 540  G   D "C4'" 1 
ATOM   2433  O  "O4'" . G   B 1 40  ? 74.359  42.067  111.265 1.00 54.07  ? 540  G   D "O4'" 1 
ATOM   2434  C  "C3'" . G   B 1 40  ? 72.658  43.678  111.247 1.00 57.10  ? 540  G   D "C3'" 1 
ATOM   2435  O  "O3'" . G   B 1 40  ? 71.667  44.314  110.455 1.00 66.67  ? 540  G   D "O3'" 1 
ATOM   2436  C  "C2'" . G   B 1 40  ? 72.128  42.451  111.981 1.00 57.96  ? 540  G   D "C2'" 1 
ATOM   2437  O  "O2'" . G   B 1 40  ? 71.306  41.625  111.183 1.00 56.89  ? 540  G   D "O2'" 1 
ATOM   2438  C  "C1'" . G   B 1 40  ? 73.430  41.702  112.279 1.00 55.35  ? 540  G   D "C1'" 1 
ATOM   2439  N  N9    . G   B 1 40  ? 73.992  42.090  113.566 1.00 45.51  ? 540  G   D N9    1 
ATOM   2440  C  C8    . G   B 1 40  ? 75.050  42.937  113.780 1.00 46.53  ? 540  G   D C8    1 
ATOM   2441  N  N7    . G   B 1 40  ? 75.321  43.107  115.045 1.00 48.80  ? 540  G   D N7    1 
ATOM   2442  C  C5    . G   B 1 40  ? 74.386  42.318  115.706 1.00 45.55  ? 540  G   D C5    1 
ATOM   2443  C  C6    . G   B 1 40  ? 74.199  42.079  117.095 1.00 44.85  ? 540  G   D C6    1 
ATOM   2444  O  O6    . G   B 1 40  ? 74.841  42.531  118.047 1.00 52.41  ? 540  G   D O6    1 
ATOM   2445  N  N1    . G   B 1 40  ? 73.139  41.215  117.327 1.00 38.41  ? 540  G   D N1    1 
ATOM   2446  C  C2    . G   B 1 40  ? 72.354  40.658  116.357 1.00 43.06  ? 540  G   D C2    1 
ATOM   2447  N  N2    . G   B 1 40  ? 71.359  39.882  116.789 1.00 36.19  ? 540  G   D N2    1 
ATOM   2448  N  N3    . G   B 1 40  ? 72.528  40.855  115.057 1.00 46.83  ? 540  G   D N3    1 
ATOM   2449  C  C4    . G   B 1 40  ? 73.556  41.689  114.807 1.00 39.62  ? 540  G   D C4    1 
ATOM   2450  P  P     . C   B 1 41  ? 70.875  45.591  111.040 1.00 67.40  ? 541  C   D P     1 
ATOM   2451  O  OP1   . C   B 1 41  ? 70.082  46.124  109.901 1.00 75.02  ? 541  C   D OP1   1 
ATOM   2452  O  OP2   . C   B 1 41  ? 71.824  46.482  111.751 1.00 70.35  ? 541  C   D OP2   1 
ATOM   2453  O  "O5'" . C   B 1 41  ? 69.902  44.976  112.136 1.00 54.16  ? 541  C   D "O5'" 1 
ATOM   2454  C  "C5'" . C   B 1 41  ? 68.922  44.024  111.759 1.00 56.26  ? 541  C   D "C5'" 1 
ATOM   2455  C  "C4'" . C   B 1 41  ? 68.265  43.442  112.980 1.00 55.94  ? 541  C   D "C4'" 1 
ATOM   2456  O  "O4'" . C   B 1 41  ? 69.244  42.692  113.747 1.00 51.45  ? 541  C   D "O4'" 1 
ATOM   2457  C  "C3'" . C   B 1 41  ? 67.732  44.451  113.984 1.00 55.82  ? 541  C   D "C3'" 1 
ATOM   2458  O  "O3'" . C   B 1 41  ? 66.468  44.978  113.603 1.00 56.03  ? 541  C   D "O3'" 1 
ATOM   2459  C  "C2'" . C   B 1 41  ? 67.628  43.595  115.237 1.00 53.98  ? 541  C   D "C2'" 1 
ATOM   2460  O  "O2'" . C   B 1 41  ? 66.479  42.769  115.218 1.00 57.16  ? 541  C   D "O2'" 1 
ATOM   2461  C  "C1'" . C   B 1 41  ? 68.908  42.757  115.126 1.00 49.87  ? 541  C   D "C1'" 1 
ATOM   2462  N  N1    . C   B 1 41  ? 70.022  43.385  115.855 1.00 44.85  ? 541  C   D N1    1 
ATOM   2463  C  C2    . C   B 1 41  ? 70.100  43.190  117.237 1.00 52.91  ? 541  C   D C2    1 
ATOM   2464  O  O2    . C   B 1 41  ? 69.237  42.477  117.790 1.00 57.61  ? 541  C   D O2    1 
ATOM   2465  N  N3    . C   B 1 41  ? 71.097  43.782  117.938 1.00 43.03  ? 541  C   D N3    1 
ATOM   2466  C  C4    . C   B 1 41  ? 71.987  44.551  117.306 1.00 45.31  ? 541  C   D C4    1 
ATOM   2467  N  N4    . C   B 1 41  ? 72.934  45.135  118.039 1.00 40.25  ? 541  C   D N4    1 
ATOM   2468  C  C5    . C   B 1 41  ? 71.937  44.760  115.895 1.00 35.52  ? 541  C   D C5    1 
ATOM   2469  C  C6    . C   B 1 41  ? 70.949  44.158  115.213 1.00 41.44  ? 541  C   D C6    1 
ATOM   2470  P  P     . C   B 1 42  ? 66.045  46.445  114.096 1.00 63.32  ? 542  C   D P     1 
ATOM   2471  O  OP1   . C   B 1 42  ? 64.765  46.768  113.429 1.00 73.15  ? 542  C   D OP1   1 
ATOM   2472  O  OP2   . C   B 1 42  ? 67.204  47.351  113.920 1.00 65.19  ? 542  C   D OP2   1 
ATOM   2473  O  "O5'" . C   B 1 42  ? 65.807  46.283  115.665 1.00 55.40  ? 542  C   D "O5'" 1 
ATOM   2474  C  "C5'" . C   B 1 42  ? 64.725  45.509  116.139 1.00 57.99  ? 542  C   D "C5'" 1 
ATOM   2475  C  "C4'" . C   B 1 42  ? 64.814  45.314  117.628 1.00 55.07  ? 542  C   D "C4'" 1 
ATOM   2476  O  "O4'" . C   B 1 42  ? 66.063  44.663  117.952 1.00 60.92  ? 542  C   D "O4'" 1 
ATOM   2477  C  "C3'" . C   B 1 42  ? 64.828  46.548  118.505 1.00 54.22  ? 542  C   D "C3'" 1 
ATOM   2478  O  "O3'" . C   B 1 42  ? 63.513  47.063  118.694 1.00 64.29  ? 542  C   D "O3'" 1 
ATOM   2479  C  "C2'" . C   B 1 42  ? 65.378  45.971  119.800 1.00 59.99  ? 542  C   D "C2'" 1 
ATOM   2480  O  "O2'" . C   B 1 42  ? 64.409  45.242  120.520 1.00 59.75  ? 542  C   D "O2'" 1 
ATOM   2481  C  "C1'" . C   B 1 42  ? 66.448  45.007  119.275 1.00 55.19  ? 542  C   D "C1'" 1 
ATOM   2482  N  N1    . C   B 1 42  ? 67.783  45.631  119.222 1.00 49.13  ? 542  C   D N1    1 
ATOM   2483  C  C2    . C   B 1 42  ? 68.513  45.794  120.415 1.00 50.91  ? 542  C   D C2    1 
ATOM   2484  O  O2    . C   B 1 42  ? 68.039  45.371  121.479 1.00 45.86  ? 542  C   D O2    1 
ATOM   2485  N  N3    . C   B 1 42  ? 69.719  46.408  120.372 1.00 57.16  ? 542  C   D N3    1 
ATOM   2486  C  C4    . C   B 1 42  ? 70.203  46.848  119.201 1.00 58.10  ? 542  C   D C4    1 
ATOM   2487  N  N4    . C   B 1 42  ? 71.397  47.456  119.206 1.00 46.15  ? 542  C   D N4    1 
ATOM   2488  C  C5    . C   B 1 42  ? 69.485  46.682  117.973 1.00 46.97  ? 542  C   D C5    1 
ATOM   2489  C  C6    . C   B 1 42  ? 68.296  46.069  118.031 1.00 47.38  ? 542  C   D C6    1 
ATOM   2490  P  P     . G   B 1 43  ? 63.297  48.636  118.973 1.00 58.75  ? 543  G   D P     1 
ATOM   2491  O  OP1   . G   B 1 43  ? 61.831  48.893  118.980 1.00 66.07  ? 543  G   D OP1   1 
ATOM   2492  O  OP2   . G   B 1 43  ? 64.170  49.415  118.059 1.00 55.94  ? 543  G   D OP2   1 
ATOM   2493  O  "O5'" . G   B 1 43  ? 63.850  48.840  120.450 1.00 49.56  ? 543  G   D "O5'" 1 
ATOM   2494  C  "C5'" . G   B 1 43  ? 63.331  48.073  121.520 1.00 46.94  ? 543  G   D "C5'" 1 
ATOM   2495  C  "C4'" . G   B 1 43  ? 64.169  48.268  122.754 1.00 49.48  ? 543  G   D "C4'" 1 
ATOM   2496  O  "O4'" . G   B 1 43  ? 65.523  47.818  122.500 1.00 55.79  ? 543  G   D "O4'" 1 
ATOM   2497  C  "C3'" . G   B 1 43  ? 64.357  49.710  123.172 1.00 58.58  ? 543  G   D "C3'" 1 
ATOM   2498  O  "O3'" . G   B 1 43  ? 63.213  50.178  123.876 1.00 67.56  ? 543  G   D "O3'" 1 
ATOM   2499  C  "C2'" . G   B 1 43  ? 65.617  49.639  124.032 1.00 56.01  ? 543  G   D "C2'" 1 
ATOM   2500  O  "O2'" . G   B 1 43  ? 65.397  49.224  125.361 1.00 52.86  ? 543  G   D "O2'" 1 
ATOM   2501  C  "C1'" . G   B 1 43  ? 66.426  48.564  123.303 1.00 54.10  ? 543  G   D "C1'" 1 
ATOM   2502  N  N9    . G   B 1 43  ? 67.500  49.094  122.462 1.00 44.59  ? 543  G   D N9    1 
ATOM   2503  C  C8    . G   B 1 43  ? 67.539  49.173  121.090 1.00 40.62  ? 543  G   D C8    1 
ATOM   2504  N  N7    . G   B 1 43  ? 68.653  49.686  120.640 1.00 41.23  ? 543  G   D N7    1 
ATOM   2505  C  C5    . G   B 1 43  ? 69.392  49.952  121.787 1.00 39.61  ? 543  G   D C5    1 
ATOM   2506  C  C6    . G   B 1 43  ? 70.701  50.496  121.939 1.00 39.96  ? 543  G   D C6    1 
ATOM   2507  O  O6    . G   B 1 43  ? 71.495  50.841  121.066 1.00 45.94  ? 543  G   D O6    1 
ATOM   2508  N  N1    . G   B 1 43  ? 71.056  50.612  123.272 1.00 31.74  ? 543  G   D N1    1 
ATOM   2509  C  C2    . G   B 1 43  ? 70.267  50.235  124.335 1.00 48.19  ? 543  G   D C2    1 
ATOM   2510  N  N2    . G   B 1 43  ? 70.797  50.419  125.565 1.00 41.04  ? 543  G   D N2    1 
ATOM   2511  N  N3    . G   B 1 43  ? 69.055  49.713  124.209 1.00 43.79  ? 543  G   D N3    1 
ATOM   2512  C  C4    . G   B 1 43  ? 68.686  49.605  122.915 1.00 35.68  ? 543  G   D C4    1 
ATOM   2513  P  P     . A   B 1 44  ? 62.839  51.736  123.823 1.00 59.36  ? 544  A   D P     1 
ATOM   2514  O  OP1   . A   B 1 44  ? 61.408  51.921  124.179 1.00 64.45  ? 544  A   D OP1   1 
ATOM   2515  O  OP2   . A   B 1 44  ? 63.324  52.225  122.505 1.00 61.62  ? 544  A   D OP2   1 
ATOM   2516  O  "O5'" . A   B 1 44  ? 63.747  52.348  124.977 1.00 43.08  ? 544  A   D "O5'" 1 
ATOM   2517  C  "C5'" . A   B 1 44  ? 63.591  51.947  126.325 1.00 39.75  ? 544  A   D "C5'" 1 
ATOM   2518  C  "C4'" . A   B 1 44  ? 64.747  52.456  127.156 1.00 50.15  ? 544  A   D "C4'" 1 
ATOM   2519  O  "O4'" . A   B 1 44  ? 65.966  51.835  126.669 1.00 59.85  ? 544  A   D "O4'" 1 
ATOM   2520  C  "C3'" . A   B 1 44  ? 65.057  53.943  127.070 1.00 50.56  ? 544  A   D "C3'" 1 
ATOM   2521  O  "O3'" . A   B 1 44  ? 64.205  54.764  127.881 1.00 53.29  ? 544  A   D "O3'" 1 
ATOM   2522  C  "C2'" . A   B 1 44  ? 66.521  53.982  127.510 1.00 47.56  ? 544  A   D "C2'" 1 
ATOM   2523  O  "O2'" . A   B 1 44  ? 66.741  53.888  128.903 1.00 46.86  ? 544  A   D "O2'" 1 
ATOM   2524  C  "C1'" . A   B 1 44  ? 67.061  52.714  126.857 1.00 49.78  ? 544  A   D "C1'" 1 
ATOM   2525  N  N9    . A   B 1 44  ? 67.679  52.970  125.559 1.00 48.88  ? 544  A   D N9    1 
ATOM   2526  C  C8    . A   B 1 44  ? 67.137  52.851  124.298 1.00 47.68  ? 544  A   D C8    1 
ATOM   2527  N  N7    . A   B 1 44  ? 67.979  53.144  123.334 1.00 50.02  ? 544  A   D N7    1 
ATOM   2528  C  C5    . A   B 1 44  ? 69.154  53.481  124.009 1.00 48.34  ? 544  A   D C5    1 
ATOM   2529  C  C6    . A   B 1 44  ? 70.438  53.881  123.561 1.00 37.71  ? 544  A   D C6    1 
ATOM   2530  N  N6    . A   B 1 44  ? 70.766  54.046  122.281 1.00 36.03  ? 544  A   D N6    1 
ATOM   2531  N  N1    . A   B 1 44  ? 71.382  54.121  124.497 1.00 42.35  ? 544  A   D N1    1 
ATOM   2532  C  C2    . A   B 1 44  ? 71.050  53.996  125.791 1.00 47.45  ? 544  A   D C2    1 
ATOM   2533  N  N3    . A   B 1 44  ? 69.881  53.643  126.333 1.00 36.65  ? 544  A   D N3    1 
ATOM   2534  C  C4    . A   B 1 44  ? 68.973  53.388  125.378 1.00 40.13  ? 544  A   D C4    1 
ATOM   2535  P  P     . A   B 1 45  ? 63.701  56.195  127.311 1.00 62.33  ? 545  A   D P     1 
ATOM   2536  O  OP1   . A   B 1 45  ? 62.996  56.935  128.391 1.00 58.69  ? 545  A   D OP1   1 
ATOM   2537  O  OP2   . A   B 1 45  ? 63.035  56.004  125.979 1.00 48.50  ? 545  A   D OP2   1 
ATOM   2538  O  "O5'" . A   B 1 45  ? 65.046  56.985  127.037 1.00 54.03  ? 545  A   D "O5'" 1 
ATOM   2539  C  "C5'" . A   B 1 45  ? 65.853  57.423  128.109 1.00 53.72  ? 545  A   D "C5'" 1 
ATOM   2540  C  "C4'" . A   B 1 45  ? 67.047  58.148  127.569 1.00 57.72  ? 545  A   D "C4'" 1 
ATOM   2541  O  "O4'" . A   B 1 45  ? 67.883  57.206  126.837 1.00 51.93  ? 545  A   D "O4'" 1 
ATOM   2542  C  "C3'" . A   B 1 45  ? 66.755  59.206  126.516 1.00 54.05  ? 545  A   D "C3'" 1 
ATOM   2543  O  "O3'" . A   B 1 45  ? 66.299  60.426  127.103 1.00 46.50  ? 545  A   D "O3'" 1 
ATOM   2544  C  "C2'" . A   B 1 45  ? 68.145  59.373  125.925 1.00 53.27  ? 545  A   D "C2'" 1 
ATOM   2545  O  "O2'" . A   B 1 45  ? 68.950  60.129  126.811 1.00 56.15  ? 545  A   D "O2'" 1 
ATOM   2546  C  "C1'" . A   B 1 45  ? 68.626  57.915  125.865 1.00 49.32  ? 545  A   D "C1'" 1 
ATOM   2547  N  N9    . A   B 1 45  ? 68.402  57.319  124.541 1.00 54.68  ? 545  A   D N9    1 
ATOM   2548  C  C8    . A   B 1 45  ? 67.265  56.762  124.004 1.00 46.69  ? 545  A   D C8    1 
ATOM   2549  N  N7    . A   B 1 45  ? 67.371  56.474  122.721 1.00 42.10  ? 545  A   D N7    1 
ATOM   2550  C  C5    . A   B 1 45  ? 68.681  56.829  122.403 1.00 45.35  ? 545  A   D C5    1 
ATOM   2551  C  C6    . A   B 1 45  ? 69.420  56.810  121.186 1.00 37.24  ? 545  A   D C6    1 
ATOM   2552  N  N6    . A   B 1 45  ? 68.932  56.415  120.005 1.00 32.20  ? 545  A   D N6    1 
ATOM   2553  N  N1    . A   B 1 45  ? 70.698  57.233  121.226 1.00 41.98  ? 545  A   D N1    1 
ATOM   2554  C  C2    . A   B 1 45  ? 71.208  57.644  122.393 1.00 49.26  ? 545  A   D C2    1 
ATOM   2555  N  N3    . A   B 1 45  ? 70.622  57.721  123.593 1.00 58.34  ? 545  A   D N3    1 
ATOM   2556  C  C4    . A   B 1 45  ? 69.340  57.305  123.526 1.00 53.95  ? 545  A   D C4    1 
ATOM   2557  P  P     . A   B 1 46  ? 64.945  61.144  126.571 1.00 50.80  ? 546  A   D P     1 
ATOM   2558  O  OP1   . A   B 1 46  ? 64.169  61.497  127.793 1.00 54.55  ? 546  A   D OP1   1 
ATOM   2559  O  OP2   . A   B 1 46  ? 64.273  60.404  125.461 1.00 39.13  ? 546  A   D OP2   1 
ATOM   2560  O  "O5'" . A   B 1 46  ? 65.459  62.506  125.924 1.00 53.18  ? 546  A   D "O5'" 1 
ATOM   2561  C  "C5'" . A   B 1 46  ? 66.389  63.350  126.608 1.00 44.58  ? 546  A   D "C5'" 1 
ATOM   2562  C  "C4'" . A   B 1 46  ? 66.816  64.481  125.700 1.00 57.62  ? 546  A   D "C4'" 1 
ATOM   2563  O  "O4'" . A   B 1 46  ? 67.533  63.955  124.548 1.00 57.30  ? 546  A   D "O4'" 1 
ATOM   2564  C  "C3'" . A   B 1 46  ? 65.666  65.256  125.086 1.00 56.28  ? 546  A   D "C3'" 1 
ATOM   2565  O  "O3'" . A   B 1 46  ? 65.237  66.243  126.011 1.00 63.39  ? 546  A   D "O3'" 1 
ATOM   2566  C  "C2'" . A   B 1 46  ? 66.300  65.862  123.833 1.00 51.88  ? 546  A   D "C2'" 1 
ATOM   2567  O  "O2'" . A   B 1 46  ? 67.036  67.050  124.067 1.00 51.24  ? 546  A   D "O2'" 1 
ATOM   2568  C  "C1'" . A   B 1 46  ? 67.258  64.749  123.404 1.00 44.83  ? 546  A   D "C1'" 1 
ATOM   2569  N  N9    . A   B 1 46  ? 66.724  63.895  122.344 1.00 41.46  ? 546  A   D N9    1 
ATOM   2570  C  C8    . A   B 1 46  ? 65.642  63.057  122.400 1.00 38.50  ? 546  A   D C8    1 
ATOM   2571  N  N7    . A   B 1 46  ? 65.353  62.482  121.254 1.00 40.34  ? 546  A   D N7    1 
ATOM   2572  C  C5    . A   B 1 46  ? 66.329  62.960  120.386 1.00 48.88  ? 546  A   D C5    1 
ATOM   2573  C  C6    . A   B 1 46  ? 66.575  62.739  119.007 1.00 45.06  ? 546  A   D C6    1 
ATOM   2574  N  N6    . A   B 1 46  ? 65.819  61.956  118.231 1.00 41.12  ? 546  A   D N6    1 
ATOM   2575  N  N1    . A   B 1 46  ? 67.639  63.366  118.451 1.00 44.34  ? 546  A   D N1    1 
ATOM   2576  C  C2    . A   B 1 46  ? 68.397  64.156  119.229 1.00 38.44  ? 546  A   D C2    1 
ATOM   2577  N  N3    . A   B 1 46  ? 68.268  64.441  120.524 1.00 38.78  ? 546  A   D N3    1 
ATOM   2578  C  C4    . A   B 1 46  ? 67.199  63.809  121.051 1.00 44.85  ? 546  A   D C4    1 
ATOM   2579  P  P     . C   B 1 47  ? 63.678  66.595  126.139 1.00 62.85  ? 548  C   D P     1 
ATOM   2580  O  OP1   . C   B 1 47  ? 63.627  67.503  127.310 1.00 63.28  ? 548  C   D OP1   1 
ATOM   2581  O  OP2   . C   B 1 47  ? 62.877  65.337  126.121 1.00 62.77  ? 548  C   D OP2   1 
ATOM   2582  O  "O5'" . C   B 1 47  ? 63.323  67.393  124.806 1.00 63.11  ? 548  C   D "O5'" 1 
ATOM   2583  C  "C5'" . C   B 1 47  ? 63.577  68.795  124.695 1.00 63.14  ? 548  C   D "C5'" 1 
ATOM   2584  C  "C4'" . C   B 1 47  ? 64.759  69.034  123.787 1.00 52.57  ? 548  C   D "C4'" 1 
ATOM   2585  O  "O4'" . C   B 1 47  ? 64.538  68.315  122.553 1.00 58.84  ? 548  C   D "O4'" 1 
ATOM   2586  C  "C3'" . C   B 1 47  ? 64.905  70.502  123.410 1.00 49.96  ? 548  C   D "C3'" 1 
ATOM   2587  O  "O3'" . C   B 1 47  ? 66.264  70.929  123.538 1.00 69.46  ? 548  C   D "O3'" 1 
ATOM   2588  C  "C2'" . C   B 1 47  ? 64.237  70.641  122.039 1.00 49.42  ? 548  C   D "C2'" 1 
ATOM   2589  O  "O2'" . C   B 1 47  ? 64.945  71.459  121.143 1.00 48.59  ? 548  C   D "O2'" 1 
ATOM   2590  C  "C1'" . C   B 1 47  ? 64.346  69.219  121.491 1.00 53.08  ? 548  C   D "C1'" 1 
ATOM   2591  N  N1    . C   B 1 47  ? 63.294  68.711  120.597 1.00 58.92  ? 548  C   D N1    1 
ATOM   2592  C  C2    . C   B 1 47  ? 63.564  68.640  119.212 1.00 57.57  ? 548  C   D C2    1 
ATOM   2593  O  O2    . C   B 1 47  ? 64.675  69.014  118.784 1.00 60.47  ? 548  C   D O2    1 
ATOM   2594  N  N3    . C   B 1 47  ? 62.611  68.164  118.383 1.00 49.97  ? 548  C   D N3    1 
ATOM   2595  C  C4    . C   B 1 47  ? 61.439  67.761  118.877 1.00 46.49  ? 548  C   D C4    1 
ATOM   2596  N  N4    . C   B 1 47  ? 60.538  67.274  118.021 1.00 45.69  ? 548  C   D N4    1 
ATOM   2597  C  C5    . C   B 1 47  ? 61.139  67.830  120.266 1.00 45.93  ? 548  C   D C5    1 
ATOM   2598  C  C6    . C   B 1 47  ? 62.084  68.308  121.084 1.00 54.81  ? 548  C   D C6    1 
ATOM   2599  P  P     . G   B 1 48  ? 66.616  72.429  123.996 1.00 74.57  ? 549  G   D P     1 
ATOM   2600  O  OP1   . G   B 1 48  ? 65.833  73.372  123.153 1.00 70.03  ? 549  G   D OP1   1 
ATOM   2601  O  OP2   . G   B 1 48  ? 68.094  72.572  124.084 1.00 68.01  ? 549  G   D OP2   1 
ATOM   2602  O  "O5'" . G   B 1 48  ? 66.072  72.494  125.483 1.00 83.46  ? 549  G   D "O5'" 1 
ATOM   2603  C  "C5'" . G   B 1 48  ? 66.449  71.515  126.438 1.00 86.42  ? 549  G   D "C5'" 1 
ATOM   2604  C  "C4'" . G   B 1 48  ? 66.510  72.147  127.797 1.00 92.85  ? 549  G   D "C4'" 1 
ATOM   2605  O  "O4'" . G   B 1 48  ? 67.727  72.938  127.918 1.00 96.78  ? 549  G   D "O4'" 1 
ATOM   2606  C  "C3'" . G   B 1 48  ? 65.394  73.147  128.025 1.00 92.42  ? 549  G   D "C3'" 1 
ATOM   2607  O  "O3'" . G   B 1 48  ? 64.191  72.517  128.430 1.00 86.23  ? 549  G   D "O3'" 1 
ATOM   2608  C  "C2'" . G   B 1 48  ? 66.001  74.046  129.086 1.00 95.44  ? 549  G   D "C2'" 1 
ATOM   2609  O  "O2'" . G   B 1 48  ? 65.997  73.434  130.359 1.00 94.94  ? 549  G   D "O2'" 1 
ATOM   2610  C  "C1'" . G   B 1 48  ? 67.434  74.169  128.564 1.00 97.16  ? 549  G   D "C1'" 1 
ATOM   2611  N  N9    . G   B 1 48  ? 67.568  75.234  127.574 1.00 98.56  ? 549  G   D N9    1 
ATOM   2612  C  C8    . G   B 1 48  ? 67.865  75.087  126.242 1.00 98.99  ? 549  G   D C8    1 
ATOM   2613  N  N7    . G   B 1 48  ? 67.887  76.218  125.594 1.00 100.28 ? 549  G   D N7    1 
ATOM   2614  C  C5    . G   B 1 48  ? 67.595  77.171  126.557 1.00 104.79 ? 549  G   D C5    1 
ATOM   2615  C  C6    . G   B 1 48  ? 67.470  78.586  126.446 1.00 109.96 ? 549  G   D C6    1 
ATOM   2616  O  O6    . G   B 1 48  ? 67.601  79.301  125.440 1.00 106.81 ? 549  G   D O6    1 
ATOM   2617  N  N1    . G   B 1 48  ? 67.153  79.165  127.670 1.00 113.68 ? 549  G   D N1    1 
ATOM   2618  C  C2    . G   B 1 48  ? 66.979  78.475  128.850 1.00 114.48 ? 549  G   D C2    1 
ATOM   2619  N  N2    . G   B 1 48  ? 66.670  79.211  129.928 1.00 120.48 ? 549  G   D N2    1 
ATOM   2620  N  N3    . G   B 1 48  ? 67.099  77.162  128.964 1.00 108.90 ? 549  G   D N3    1 
ATOM   2621  C  C4    . G   B 1 48  ? 67.403  76.579  127.787 1.00 102.48 ? 549  G   D C4    1 
ATOM   2622  P  P     . G   B 1 49  ? 62.784  73.154  127.988 1.00 95.02  ? 550  G   D P     1 
ATOM   2623  O  OP1   . G   B 1 49  ? 61.700  72.230  128.407 1.00 101.94 ? 550  G   D OP1   1 
ATOM   2624  O  OP2   . G   B 1 49  ? 62.887  73.563  126.565 1.00 85.24  ? 550  G   D OP2   1 
ATOM   2625  O  "O5'" . G   B 1 49  ? 62.680  74.470  128.880 1.00 101.40 ? 550  G   D "O5'" 1 
ATOM   2626  C  "C5'" . G   B 1 49  ? 62.734  74.387  130.305 1.00 102.38 ? 550  G   D "C5'" 1 
ATOM   2627  C  "C4'" . G   B 1 49  ? 62.514  75.747  130.926 1.00 103.15 ? 550  G   D "C4'" 1 
ATOM   2628  O  "O4'" . G   B 1 49  ? 63.677  76.595  130.718 1.00 103.41 ? 550  G   D "O4'" 1 
ATOM   2629  C  "C3'" . G   B 1 49  ? 61.369  76.555  130.345 1.00 102.57 ? 550  G   D "C3'" 1 
ATOM   2630  O  "O3'" . G   B 1 49  ? 60.118  76.167  130.883 1.00 106.89 ? 550  G   D "O3'" 1 
ATOM   2631  C  "C2'" . G   B 1 49  ? 61.747  77.960  130.776 1.00 106.03 ? 550  G   D "C2'" 1 
ATOM   2632  O  "O2'" . G   B 1 49  ? 61.477  78.166  132.150 1.00 107.23 ? 550  G   D "O2'" 1 
ATOM   2633  C  "C1'" . G   B 1 49  ? 63.258  77.940  130.529 1.00 107.94 ? 550  G   D "C1'" 1 
ATOM   2634  N  N9    . G   B 1 49  ? 63.602  78.339  129.163 1.00 111.51 ? 550  G   D N9    1 
ATOM   2635  C  C8    . G   B 1 49  ? 63.844  77.503  128.098 1.00 109.82 ? 550  G   D C8    1 
ATOM   2636  N  N7    . G   B 1 49  ? 64.109  78.142  126.992 1.00 108.45 ? 550  G   D N7    1 
ATOM   2637  C  C5    . G   B 1 49  ? 64.048  79.483  127.344 1.00 110.09 ? 550  G   D C5    1 
ATOM   2638  C  C6    . G   B 1 49  ? 64.252  80.648  126.559 1.00 110.54 ? 550  G   D C6    1 
ATOM   2639  O  O6    . G   B 1 49  ? 64.539  80.728  125.356 1.00 108.96 ? 550  G   D O6    1 
ATOM   2640  N  N1    . G   B 1 49  ? 64.088  81.808  127.313 1.00 108.59 ? 550  G   D N1    1 
ATOM   2641  C  C2    . G   B 1 49  ? 63.773  81.844  128.650 1.00 107.47 ? 550  G   D C2    1 
ATOM   2642  N  N2    . G   B 1 49  ? 63.655  83.064  129.196 1.00 101.59 ? 550  G   D N2    1 
ATOM   2643  N  N3    . G   B 1 49  ? 63.588  80.765  129.395 1.00 109.15 ? 550  G   D N3    1 
ATOM   2644  C  C4    . G   B 1 49  ? 63.738  79.626  128.682 1.00 110.59 ? 550  G   D C4    1 
ATOM   2645  P  P     . G   B 1 50  ? 58.780  76.479  130.059 1.00 112.72 ? 551  G   D P     1 
ATOM   2646  O  OP1   . G   B 1 50  ? 57.622  75.891  130.780 1.00 116.95 ? 551  G   D OP1   1 
ATOM   2647  O  OP2   . G   B 1 50  ? 59.049  76.084  128.653 1.00 110.23 ? 551  G   D OP2   1 
ATOM   2648  O  "O5'" . G   B 1 50  ? 58.657  78.064  130.131 1.00 111.67 ? 551  G   D "O5'" 1 
ATOM   2649  C  "C5'" . G   B 1 50  ? 58.505  78.731  131.385 1.00 115.46 ? 551  G   D "C5'" 1 
ATOM   2650  C  "C4'" . G   B 1 50  ? 58.501  80.230  131.184 1.00 117.92 ? 551  G   D "C4'" 1 
ATOM   2651  O  "O4'" . G   B 1 50  ? 59.822  80.687  130.776 1.00 119.24 ? 551  G   D "O4'" 1 
ATOM   2652  C  "C3'" . G   B 1 50  ? 57.590  80.716  130.072 1.00 119.17 ? 551  G   D "C3'" 1 
ATOM   2653  O  "O3'" . G   B 1 50  ? 56.249  80.843  130.503 1.00 117.76 ? 551  G   D "O3'" 1 
ATOM   2654  C  "C2'" . G   B 1 50  ? 58.206  82.060  129.717 1.00 119.54 ? 551  G   D "C2'" 1 
ATOM   2655  O  "O2'" . G   B 1 50  ? 57.861  83.082  130.630 1.00 120.77 ? 551  G   D "O2'" 1 
ATOM   2656  C  "C1'" . G   B 1 50  ? 59.696  81.733  129.821 1.00 117.61 ? 551  G   D "C1'" 1 
ATOM   2657  N  N9    . G   B 1 50  ? 60.237  81.264  128.546 1.00 117.65 ? 551  G   D N9    1 
ATOM   2658  C  C8    . G   B 1 50  ? 60.470  79.963  128.165 1.00 115.10 ? 551  G   D C8    1 
ATOM   2659  N  N7    . G   B 1 50  ? 60.939  79.861  126.951 1.00 113.27 ? 551  G   D N7    1 
ATOM   2660  C  C5    . G   B 1 50  ? 61.024  81.172  126.505 1.00 116.72 ? 551  G   D C5    1 
ATOM   2661  C  C6    . G   B 1 50  ? 61.465  81.696  125.260 1.00 116.89 ? 551  G   D C6    1 
ATOM   2662  O  O6    . G   B 1 50  ? 61.883  81.085  124.269 1.00 116.37 ? 551  G   D O6    1 
ATOM   2663  N  N1    . G   B 1 50  ? 61.389  83.083  125.234 1.00 119.77 ? 551  G   D N1    1 
ATOM   2664  C  C2    . G   B 1 50  ? 60.948  83.871  126.269 1.00 119.75 ? 551  G   D C2    1 
ATOM   2665  N  N2    . G   B 1 50  ? 60.950  85.197  126.048 1.00 117.49 ? 551  G   D N2    1 
ATOM   2666  N  N3    . G   B 1 50  ? 60.536  83.396  127.433 1.00 118.06 ? 551  G   D N3    1 
ATOM   2667  C  C4    . G   B 1 50  ? 60.600  82.050  127.480 1.00 115.77 ? 551  G   D C4    1 
ATOM   2668  P  P     . G   B 1 51  ? 55.090  80.987  129.410 1.00 122.95 ? 552  G   D P     1 
ATOM   2669  O  OP1   . G   B 1 51  ? 53.799  80.562  130.011 1.00 126.13 ? 552  G   D OP1   1 
ATOM   2670  O  OP2   . G   B 1 51  ? 55.578  80.332  128.165 1.00 116.84 ? 552  G   D OP2   1 
ATOM   2671  O  "O5'" . G   B 1 51  ? 55.016  82.549  129.132 1.00 116.18 ? 552  G   D "O5'" 1 
ATOM   2672  C  "C5'" . G   B 1 51  ? 54.349  83.029  127.981 1.00 112.76 ? 552  G   D "C5'" 1 
ATOM   2673  C  "C4'" . G   B 1 51  ? 54.948  84.334  127.546 1.00 111.83 ? 552  G   D "C4'" 1 
ATOM   2674  O  "O4'" . G   B 1 51  ? 56.396  84.245  127.591 1.00 107.99 ? 552  G   D "O4'" 1 
ATOM   2675  C  "C3'" . G   B 1 51  ? 54.624  84.697  126.109 1.00 112.12 ? 552  G   D "C3'" 1 
ATOM   2676  O  "O3'" . G   B 1 51  ? 53.356  85.330  126.029 1.00 112.76 ? 552  G   D "O3'" 1 
ATOM   2677  C  "C2'" . G   B 1 51  ? 55.793  85.601  125.749 1.00 110.79 ? 552  G   D "C2'" 1 
ATOM   2678  O  "O2'" . G   B 1 51  ? 55.669  86.902  126.282 1.00 108.93 ? 552  G   D "O2'" 1 
ATOM   2679  C  "C1'" . G   B 1 51  ? 56.945  84.868  126.441 1.00 108.98 ? 552  G   D "C1'" 1 
ATOM   2680  N  N9    . G   B 1 51  ? 57.509  83.823  125.591 1.00 106.81 ? 552  G   D N9    1 
ATOM   2681  C  C8    . G   B 1 51  ? 57.525  82.471  125.836 1.00 102.70 ? 552  G   D C8    1 
ATOM   2682  N  N7    . G   B 1 51  ? 58.075  81.784  124.874 1.00 101.32 ? 552  G   D N7    1 
ATOM   2683  C  C5    . G   B 1 51  ? 58.449  82.739  123.939 1.00 105.47 ? 552  G   D C5    1 
ATOM   2684  C  C6    . G   B 1 51  ? 59.086  82.596  122.676 1.00 105.71 ? 552  G   D C6    1 
ATOM   2685  O  O6    . G   B 1 51  ? 59.454  81.561  122.109 1.00 102.09 ? 552  G   D O6    1 
ATOM   2686  N  N1    . G   B 1 51  ? 59.282  83.829  122.059 1.00 109.62 ? 552  G   D N1    1 
ATOM   2687  C  C2    . G   B 1 51  ? 58.915  85.044  122.584 1.00 106.65 ? 552  G   D C2    1 
ATOM   2688  N  N2    . G   B 1 51  ? 59.198  86.124  121.837 1.00 98.64  ? 552  G   D N2    1 
ATOM   2689  N  N3    . G   B 1 51  ? 58.317  85.190  123.756 1.00 107.57 ? 552  G   D N3    1 
ATOM   2690  C  C4    . G   B 1 51  ? 58.116  84.005  124.373 1.00 106.74 ? 552  G   D C4    1 
ATOM   2691  P  P     . G   B 1 52  ? 52.107  84.522  125.420 1.00 117.05 ? 553  G   D P     1 
ATOM   2692  O  OP1   . G   B 1 52  ? 50.854  85.193  125.868 1.00 111.18 ? 553  G   D OP1   1 
ATOM   2693  O  OP2   . G   B 1 52  ? 52.327  83.087  125.736 1.00 113.38 ? 553  G   D OP2   1 
ATOM   2694  O  "O5'" . G   B 1 52  ? 52.241  84.752  123.851 1.00 112.07 ? 553  G   D "O5'" 1 
ATOM   2695  C  "C5'" . G   B 1 52  ? 51.896  86.014  123.307 1.00 109.41 ? 553  G   D "C5'" 1 
ATOM   2696  C  "C4'" . G   B 1 52  ? 52.980  86.526  122.390 1.00 108.65 ? 553  G   D "C4'" 1 
ATOM   2697  O  "O4'" . G   B 1 52  ? 54.277  85.984  122.749 1.00 107.47 ? 553  G   D "O4'" 1 
ATOM   2698  C  "C3'" . G   B 1 52  ? 52.815  86.135  120.938 1.00 108.44 ? 553  G   D "C3'" 1 
ATOM   2699  O  "O3'" . G   B 1 52  ? 51.898  87.040  120.352 1.00 107.90 ? 553  G   D "O3'" 1 
ATOM   2700  C  "C2'" . G   B 1 52  ? 54.224  86.323  120.386 1.00 109.57 ? 553  G   D "C2'" 1 
ATOM   2701  O  "O2'" . G   B 1 52  ? 54.512  87.661  120.026 1.00 109.61 ? 553  G   D "O2'" 1 
ATOM   2702  C  "C1'" . G   B 1 52  ? 55.086  85.894  121.579 1.00 109.04 ? 553  G   D "C1'" 1 
ATOM   2703  N  N9    . G   B 1 52  ? 55.590  84.526  121.457 1.00 107.35 ? 553  G   D N9    1 
ATOM   2704  C  C8    . G   B 1 52  ? 55.563  83.543  122.416 1.00 105.15 ? 553  G   D C8    1 
ATOM   2705  N  N7    . G   B 1 52  ? 56.074  82.415  122.007 1.00 100.04 ? 553  G   D N7    1 
ATOM   2706  C  C5    . G   B 1 52  ? 56.467  82.667  120.700 1.00 99.81  ? 553  G   D C5    1 
ATOM   2707  C  C6    . G   B 1 52  ? 57.081  81.819  119.747 1.00 100.35 ? 553  G   D C6    1 
ATOM   2708  O  O6    . G   B 1 52  ? 57.408  80.635  119.868 1.00 99.10  ? 553  G   D O6    1 
ATOM   2709  N  N1    . G   B 1 52  ? 57.308  82.478  118.545 1.00 99.38  ? 553  G   D N1    1 
ATOM   2710  C  C2    . G   B 1 52  ? 56.985  83.783  118.288 1.00 101.64 ? 553  G   D C2    1 
ATOM   2711  N  N2    . G   B 1 52  ? 57.285  84.234  117.057 1.00 102.49 ? 553  G   D N2    1 
ATOM   2712  N  N3    . G   B 1 52  ? 56.409  84.587  119.167 1.00 103.43 ? 553  G   D N3    1 
ATOM   2713  C  C4    . G   B 1 52  ? 56.182  83.966  120.345 1.00 101.43 ? 553  G   D C4    1 
ATOM   2714  P  P     . U   B 1 53  ? 50.684  86.480  119.485 1.00 107.60 ? 554  U   D P     1 
ATOM   2715  O  OP1   . U   B 1 53  ? 49.646  87.539  119.377 1.00 112.13 ? 554  U   D OP1   1 
ATOM   2716  O  OP2   . U   B 1 53  ? 50.327  85.157  120.061 1.00 109.93 ? 554  U   D OP2   1 
ATOM   2717  O  "O5'" . U   B 1 53  ? 51.354  86.275  118.061 1.00 101.77 ? 554  U   D "O5'" 1 
ATOM   2718  C  "C5'" . U   B 1 53  ? 52.088  87.325  117.448 1.00 95.19  ? 554  U   D "C5'" 1 
ATOM   2719  C  "C4'" . U   B 1 53  ? 52.815  86.792  116.247 1.00 97.08  ? 554  U   D "C4'" 1 
ATOM   2720  O  "O4'" . U   B 1 53  ? 53.984  86.047  116.671 1.00 95.48  ? 554  U   D "O4'" 1 
ATOM   2721  C  "C3'" . U   B 1 53  ? 51.996  85.786  115.459 1.00 97.29  ? 554  U   D "C3'" 1 
ATOM   2722  O  "O3'" . U   B 1 53  ? 51.073  86.428  114.592 1.00 95.03  ? 554  U   D "O3'" 1 
ATOM   2723  C  "C2'" . U   B 1 53  ? 53.071  84.975  114.749 1.00 93.24  ? 554  U   D "C2'" 1 
ATOM   2724  O  "O2'" . U   B 1 53  ? 53.569  85.600  113.585 1.00 82.72  ? 554  U   D "O2'" 1 
ATOM   2725  C  "C1'" . U   B 1 53  ? 54.152  84.911  115.835 1.00 98.98  ? 554  U   D "C1'" 1 
ATOM   2726  N  N1    . U   B 1 53  ? 54.069  83.706  116.677 1.00 103.21 ? 554  U   D N1    1 
ATOM   2727  C  C2    . U   B 1 53  ? 54.429  82.498  116.108 1.00 105.06 ? 554  U   D C2    1 
ATOM   2728  O  O2    . U   B 1 53  ? 54.792  82.396  114.952 1.00 107.06 ? 554  U   D O2    1 
ATOM   2729  N  N3    . U   B 1 53  ? 54.344  81.412  116.946 1.00 105.25 ? 554  U   D N3    1 
ATOM   2730  C  C4    . U   B 1 53  ? 53.945  81.410  118.269 1.00 105.11 ? 554  U   D C4    1 
ATOM   2731  O  O4    . U   B 1 53  ? 53.986  80.358  118.914 1.00 103.12 ? 554  U   D O4    1 
ATOM   2732  C  C5    . U   B 1 53  ? 53.576  82.696  118.780 1.00 102.40 ? 554  U   D C5    1 
ATOM   2733  C  C6    . U   B 1 53  ? 53.650  83.773  117.987 1.00 102.48 ? 554  U   D C6    1 
ATOM   2734  P  P     . U   B 1 54  ? 49.501  86.175  114.794 1.00 93.93  ? 555  U   D P     1 
ATOM   2735  O  OP1   . U   B 1 54  ? 48.763  87.136  113.940 1.00 99.76  ? 555  U   D OP1   1 
ATOM   2736  O  OP2   . U   B 1 54  ? 49.228  86.129  116.256 1.00 82.44  ? 555  U   D OP2   1 
ATOM   2737  O  "O5'" . U   B 1 54  ? 49.284  84.712  114.201 1.00 103.03 ? 555  U   D "O5'" 1 
ATOM   2738  C  "C5'" . U   B 1 54  ? 49.662  84.407  112.860 1.00 102.92 ? 555  U   D "C5'" 1 
ATOM   2739  C  "C4'" . U   B 1 54  ? 49.837  82.912  112.682 1.00 102.66 ? 555  U   D "C4'" 1 
ATOM   2740  O  "O4'" . U   B 1 54  ? 50.906  82.435  113.542 1.00 96.59  ? 555  U   D "O4'" 1 
ATOM   2741  C  "C3'" . U   B 1 54  ? 48.662  82.035  113.082 1.00 103.88 ? 555  U   D "C3'" 1 
ATOM   2742  O  "O3'" . U   B 1 54  ? 47.656  82.006  112.080 1.00 114.03 ? 555  U   D "O3'" 1 
ATOM   2743  C  "C2'" . U   B 1 54  ? 49.330  80.677  113.257 1.00 96.24  ? 555  U   D "C2'" 1 
ATOM   2744  O  "O2'" . U   B 1 54  ? 49.555  80.020  112.028 1.00 86.11  ? 555  U   D "O2'" 1 
ATOM   2745  C  "C1'" . U   B 1 54  ? 50.660  81.081  113.897 1.00 94.81  ? 555  U   D "C1'" 1 
ATOM   2746  N  N1    . U   B 1 54  ? 50.618  80.976  115.362 1.00 93.85  ? 555  U   D N1    1 
ATOM   2747  C  C2    . U   B 1 54  ? 50.996  79.771  115.919 1.00 95.42  ? 555  U   D C2    1 
ATOM   2748  O  O2    . U   B 1 54  ? 51.404  78.834  115.249 1.00 92.40  ? 555  U   D O2    1 
ATOM   2749  N  N3    . U   B 1 54  ? 50.884  79.703  117.288 1.00 93.60  ? 555  U   D N3    1 
ATOM   2750  C  C4    . U   B 1 54  ? 50.450  80.699  118.141 1.00 90.20  ? 555  U   D C4    1 
ATOM   2751  O  O4    . U   B 1 54  ? 50.330  80.457  119.347 1.00 84.99  ? 555  U   D O4    1 
ATOM   2752  C  C5    . U   B 1 54  ? 50.107  81.929  117.490 1.00 89.34  ? 555  U   D C5    1 
ATOM   2753  C  C6    . U   B 1 54  ? 50.200  82.023  116.155 1.00 92.25  ? 555  U   D C6    1 
ATOM   2754  P  P     . C   B 1 55  ? 46.107  81.987  112.515 1.00 119.27 ? 556  C   D P     1 
ATOM   2755  O  OP1   . C   B 1 55  ? 45.287  81.999  111.272 1.00 113.04 ? 556  C   D OP1   1 
ATOM   2756  O  OP2   . C   B 1 55  ? 45.913  83.050  113.543 1.00 109.53 ? 556  C   D OP2   1 
ATOM   2757  O  "O5'" . C   B 1 55  ? 45.922  80.572  113.229 1.00 116.54 ? 556  C   D "O5'" 1 
ATOM   2758  C  "C5'" . C   B 1 55  ? 44.795  80.312  114.064 1.00 110.09 ? 556  C   D "C5'" 1 
ATOM   2759  C  "C4'" . C   B 1 55  ? 44.637  78.824  114.291 1.00 105.65 ? 556  C   D "C4'" 1 
ATOM   2760  O  "O4'" . C   B 1 55  ? 44.361  78.163  113.028 1.00 101.61 ? 556  C   D "O4'" 1 
ATOM   2761  C  "C3'" . C   B 1 55  ? 45.860  78.098  114.825 1.00 103.29 ? 556  C   D "C3'" 1 
ATOM   2762  O  "O3'" . C   B 1 55  ? 45.942  78.224  116.243 1.00 108.43 ? 556  C   D "O3'" 1 
ATOM   2763  C  "C2'" . C   B 1 55  ? 45.577  76.661  114.409 1.00 101.89 ? 556  C   D "C2'" 1 
ATOM   2764  O  "O2'" . C   B 1 55  ? 44.674  76.021  115.285 1.00 100.58 ? 556  C   D "O2'" 1 
ATOM   2765  C  "C1'" . C   B 1 55  ? 44.917  76.859  113.042 1.00 101.17 ? 556  C   D "C1'" 1 
ATOM   2766  N  N1    . C   B 1 55  ? 45.858  76.751  111.918 1.00 105.69 ? 556  C   D N1    1 
ATOM   2767  C  C2    . C   B 1 55  ? 46.172  75.480  111.410 1.00 107.32 ? 556  C   D C2    1 
ATOM   2768  O  O2    . C   B 1 55  ? 45.643  74.478  111.919 1.00 102.34 ? 556  C   D O2    1 
ATOM   2769  N  N3    . C   B 1 55  ? 47.042  75.377  110.378 1.00 108.98 ? 556  C   D N3    1 
ATOM   2770  C  C4    . C   B 1 55  ? 47.590  76.478  109.855 1.00 110.25 ? 556  C   D C4    1 
ATOM   2771  N  N4    . C   B 1 55  ? 48.445  76.332  108.839 1.00 110.68 ? 556  C   D N4    1 
ATOM   2772  C  C5    . C   B 1 55  ? 47.287  77.782  110.352 1.00 112.12 ? 556  C   D C5    1 
ATOM   2773  C  C6    . C   B 1 55  ? 46.425  77.871  111.374 1.00 109.10 ? 556  C   D C6    1 
ATOM   2774  P  P     . G   B 1 56  ? 47.345  78.618  116.927 1.00 109.51 ? 557  G   D P     1 
ATOM   2775  O  OP1   . G   B 1 56  ? 47.164  78.803  118.392 1.00 99.85  ? 557  G   D OP1   1 
ATOM   2776  O  OP2   . G   B 1 56  ? 47.928  79.717  116.110 1.00 108.66 ? 557  G   D OP2   1 
ATOM   2777  O  "O5'" . G   B 1 56  ? 48.243  77.326  116.702 1.00 112.39 ? 557  G   D "O5'" 1 
ATOM   2778  C  "C5'" . G   B 1 56  ? 47.940  76.096  117.355 1.00 107.53 ? 557  G   D "C5'" 1 
ATOM   2779  C  "C4'" . G   B 1 56  ? 48.835  74.997  116.826 1.00 102.09 ? 557  G   D "C4'" 1 
ATOM   2780  O  "O4'" . G   B 1 56  ? 48.505  74.727  115.438 1.00 100.68 ? 557  G   D "O4'" 1 
ATOM   2781  C  "C3'" . G   B 1 56  ? 50.312  75.344  116.772 1.00 95.10  ? 557  G   D "C3'" 1 
ATOM   2782  O  "O3'" . G   B 1 56  ? 50.957  75.163  118.016 1.00 90.78  ? 557  G   D "O3'" 1 
ATOM   2783  C  "C2'" . G   B 1 56  ? 50.833  74.371  115.735 1.00 94.07  ? 557  G   D "C2'" 1 
ATOM   2784  O  "O2'" . G   B 1 56  ? 51.009  73.081  116.270 1.00 95.83  ? 557  G   D "O2'" 1 
ATOM   2785  C  "C1'" . G   B 1 56  ? 49.682  74.371  114.733 1.00 98.69  ? 557  G   D "C1'" 1 
ATOM   2786  N  N9    . G   B 1 56  ? 49.908  75.346  113.676 1.00 101.42 ? 557  G   D N9    1 
ATOM   2787  C  C8    . G   B 1 56  ? 49.354  76.596  113.547 1.00 104.15 ? 557  G   D C8    1 
ATOM   2788  N  N7    . G   B 1 56  ? 49.777  77.233  112.488 1.00 108.95 ? 557  G   D N7    1 
ATOM   2789  C  C5    . G   B 1 56  ? 50.658  76.346  111.884 1.00 104.81 ? 557  G   D C5    1 
ATOM   2790  C  C6    . G   B 1 56  ? 51.437  76.473  110.699 1.00 103.68 ? 557  G   D C6    1 
ATOM   2791  O  O6    . G   B 1 56  ? 51.516  77.430  109.921 1.00 106.94 ? 557  G   D O6    1 
ATOM   2792  N  N1    . G   B 1 56  ? 52.186  75.329  110.458 1.00 103.91 ? 557  G   D N1    1 
ATOM   2793  C  C2    . G   B 1 56  ? 52.198  74.212  111.253 1.00 104.05 ? 557  G   D C2    1 
ATOM   2794  N  N2    . G   B 1 56  ? 52.987  73.211  110.856 1.00 99.01  ? 557  G   D N2    1 
ATOM   2795  N  N3    . G   B 1 56  ? 51.488  74.084  112.357 1.00 106.08 ? 557  G   D N3    1 
ATOM   2796  C  C4    . G   B 1 56  ? 50.746  75.179  112.608 1.00 104.68 ? 557  G   D C4    1 
ATOM   2797  P  P     . A   B 1 57  ? 52.083  76.207  118.455 1.00 94.32  ? 558  A   D P     1 
ATOM   2798  O  OP1   . A   B 1 57  ? 51.433  77.397  119.061 1.00 100.54 ? 558  A   D OP1   1 
ATOM   2799  O  OP2   . A   B 1 57  ? 52.930  76.367  117.247 1.00 94.20  ? 558  A   D OP2   1 
ATOM   2800  O  "O5'" . A   B 1 57  ? 52.910  75.460  119.588 1.00 92.24  ? 558  A   D "O5'" 1 
ATOM   2801  C  "C5'" . A   B 1 57  ? 54.309  75.679  119.730 1.00 100.85 ? 558  A   D "C5'" 1 
ATOM   2802  C  "C4'" . A   B 1 57  ? 55.072  74.552  119.074 1.00 98.86  ? 558  A   D "C4'" 1 
ATOM   2803  O  "O4'" . A   B 1 57  ? 55.049  74.742  117.626 1.00 96.73  ? 558  A   D "O4'" 1 
ATOM   2804  C  "C3'" . A   B 1 57  ? 56.544  74.506  119.431 1.00 97.74  ? 558  A   D "C3'" 1 
ATOM   2805  O  "O3'" . A   B 1 57  ? 57.035  73.527  120.334 1.00 95.18  ? 558  A   D "O3'" 1 
ATOM   2806  C  "C2'" . A   B 1 57  ? 57.328  75.148  118.300 1.00 101.14 ? 558  A   D "C2'" 1 
ATOM   2807  O  "O2'" . A   B 1 57  ? 58.418  74.345  117.901 1.00 115.18 ? 558  A   D "O2'" 1 
ATOM   2808  C  "C1'" . A   B 1 57  ? 56.329  75.127  117.146 1.00 100.02 ? 558  A   D "C1'" 1 
ATOM   2809  N  N9    . A   B 1 57  ? 56.235  76.458  116.547 1.00 103.58 ? 558  A   D N9    1 
ATOM   2810  C  C8    . A   B 1 57  ? 55.788  77.616  117.138 1.00 106.98 ? 558  A   D C8    1 
ATOM   2811  N  N7    . A   B 1 57  ? 55.863  78.672  116.362 1.00 105.27 ? 558  A   D N7    1 
ATOM   2812  C  C5    . A   B 1 57  ? 56.388  78.176  115.177 1.00 106.93 ? 558  A   D C5    1 
ATOM   2813  C  C6    . A   B 1 57  ? 56.718  78.792  113.956 1.00 108.20 ? 558  A   D C6    1 
ATOM   2814  N  N6    . A   B 1 57  ? 56.560  80.096  113.714 1.00 106.85 ? 558  A   D N6    1 
ATOM   2815  N  N1    . A   B 1 57  ? 57.225  78.013  112.977 1.00 109.72 ? 558  A   D N1    1 
ATOM   2816  C  C2    . A   B 1 57  ? 57.386  76.707  113.218 1.00 108.49 ? 558  A   D C2    1 
ATOM   2817  N  N3    . A   B 1 57  ? 57.114  76.011  114.320 1.00 109.63 ? 558  A   D N3    1 
ATOM   2818  C  C4    . A   B 1 57  ? 56.614  76.812  115.274 1.00 107.21 ? 558  A   D C4    1 
ATOM   2819  P  P     . U   B 1 58  ? 57.488  72.094  119.783 1.00 91.51  ? 559  U   D P     1 
ATOM   2820  O  OP1   . U   B 1 58  ? 56.648  71.767  118.594 1.00 81.58  ? 559  U   D OP1   1 
ATOM   2821  O  OP2   . U   B 1 58  ? 57.499  71.182  120.958 1.00 99.44  ? 559  U   D OP2   1 
ATOM   2822  O  "O5'" . U   B 1 58  ? 58.990  72.299  119.294 1.00 92.14  ? 559  U   D "O5'" 1 
ATOM   2823  C  "C5'" . U   B 1 58  ? 60.063  72.468  120.218 1.00 78.08  ? 559  U   D "C5'" 1 
ATOM   2824  C  "C4'" . U   B 1 58  ? 61.369  72.485  119.466 1.00 78.05  ? 559  U   D "C4'" 1 
ATOM   2825  O  "O4'" . U   B 1 58  ? 61.593  71.175  118.886 1.00 77.90  ? 559  U   D "O4'" 1 
ATOM   2826  C  "C3'" . U   B 1 58  ? 61.398  73.440  118.278 1.00 73.00  ? 559  U   D "C3'" 1 
ATOM   2827  O  "O3'" . U   B 1 58  ? 61.819  74.731  118.711 1.00 71.95  ? 559  U   D "O3'" 1 
ATOM   2828  C  "C2'" . U   B 1 58  ? 62.446  72.806  117.371 1.00 72.36  ? 559  U   D "C2'" 1 
ATOM   2829  O  "O2'" . U   B 1 58  ? 63.762  73.127  117.765 1.00 76.79  ? 559  U   D "O2'" 1 
ATOM   2830  C  "C1'" . U   B 1 58  ? 62.210  71.315  117.616 1.00 73.78  ? 559  U   D "C1'" 1 
ATOM   2831  N  N1    . U   B 1 58  ? 61.354  70.677  116.609 1.00 67.68  ? 559  U   D N1    1 
ATOM   2832  C  C2    . U   B 1 58  ? 61.873  70.506  115.334 1.00 70.16  ? 559  U   D C2    1 
ATOM   2833  O  O2    . U   B 1 58  ? 62.994  70.871  115.018 1.00 61.07  ? 559  U   D O2    1 
ATOM   2834  N  N3    . U   B 1 58  ? 61.028  69.891  114.443 1.00 69.23  ? 559  U   D N3    1 
ATOM   2835  C  C4    . U   B 1 58  ? 59.744  69.443  114.692 1.00 67.70  ? 559  U   D C4    1 
ATOM   2836  O  O4    . U   B 1 58  ? 59.088  68.939  113.776 1.00 62.15  ? 559  U   D O4    1 
ATOM   2837  C  C5    . U   B 1 58  ? 59.284  69.664  116.033 1.00 65.12  ? 559  U   D C5    1 
ATOM   2838  C  C6    . U   B 1 58  ? 60.086  70.261  116.919 1.00 60.53  ? 559  U   D C6    1 
ATOM   2839  P  P     . U   B 1 59  ? 61.305  76.057  117.952 1.00 68.89  ? 560  U   D P     1 
ATOM   2840  O  OP1   . U   B 1 59  ? 62.117  77.155  118.532 1.00 66.97  ? 560  U   D OP1   1 
ATOM   2841  O  OP2   . U   B 1 59  ? 59.838  76.127  118.029 1.00 66.98  ? 560  U   D OP2   1 
ATOM   2842  O  "O5'" . U   B 1 59  ? 61.712  75.852  116.420 1.00 65.64  ? 560  U   D "O5'" 1 
ATOM   2843  C  "C5'" . U   B 1 59  ? 63.081  75.897  116.047 1.00 58.90  ? 560  U   D "C5'" 1 
ATOM   2844  C  "C4'" . U   B 1 59  ? 63.272  75.601  114.575 1.00 63.19  ? 560  U   D "C4'" 1 
ATOM   2845  O  "O4'" . U   B 1 59  ? 62.626  74.343  114.257 1.00 59.81  ? 560  U   D "O4'" 1 
ATOM   2846  C  "C3'" . U   B 1 59  ? 62.622  76.644  113.670 1.00 64.36  ? 560  U   D "C3'" 1 
ATOM   2847  O  "O3'" . U   B 1 59  ? 63.479  77.192  112.674 1.00 64.04  ? 560  U   D "O3'" 1 
ATOM   2848  C  "C2'" . U   B 1 59  ? 61.299  76.051  113.202 1.00 68.64  ? 560  U   D "C2'" 1 
ATOM   2849  O  "O2'" . U   B 1 59  ? 61.093  76.246  111.815 1.00 65.95  ? 560  U   D "O2'" 1 
ATOM   2850  C  "C1'" . U   B 1 59  ? 61.550  74.557  113.375 1.00 67.72  ? 560  U   D "C1'" 1 
ATOM   2851  N  N1    . U   B 1 59  ? 60.404  73.728  113.760 1.00 65.91  ? 560  U   D N1    1 
ATOM   2852  C  C2    . U   B 1 59  ? 59.824  72.989  112.749 1.00 64.43  ? 560  U   D C2    1 
ATOM   2853  O  O2    . U   B 1 59  ? 60.255  72.996  111.605 1.00 53.99  ? 560  U   D O2    1 
ATOM   2854  N  N3    . U   B 1 59  ? 58.734  72.244  113.123 1.00 64.58  ? 560  U   D N3    1 
ATOM   2855  C  C4    . U   B 1 59  ? 58.182  72.169  114.389 1.00 73.58  ? 560  U   D C4    1 
ATOM   2856  O  O4    . U   B 1 59  ? 57.193  71.453  114.579 1.00 77.87  ? 560  U   D O4    1 
ATOM   2857  C  C5    . U   B 1 59  ? 58.857  72.958  115.387 1.00 67.40  ? 560  U   D C5    1 
ATOM   2858  C  C6    . U   B 1 59  ? 59.920  73.690  115.045 1.00 64.67  ? 560  U   D C6    1 
ATOM   2859  P  P     . C   B 1 60  ? 64.403  78.456  113.023 1.00 76.26  ? 561  C   D P     1 
ATOM   2860  O  OP1   . C   B 1 60  ? 65.462  78.514  111.977 1.00 68.64  ? 561  C   D OP1   1 
ATOM   2861  O  OP2   . C   B 1 60  ? 64.784  78.378  114.460 1.00 53.62  ? 561  C   D OP2   1 
ATOM   2862  O  "O5'" . C   B 1 60  ? 63.428  79.705  112.838 1.00 79.86  ? 561  C   D "O5'" 1 
ATOM   2863  C  "C5'" . C   B 1 60  ? 63.303  80.360  111.576 1.00 83.09  ? 561  C   D "C5'" 1 
ATOM   2864  C  "C4'" . C   B 1 60  ? 62.429  81.585  111.710 1.00 86.80  ? 561  C   D "C4'" 1 
ATOM   2865  O  "O4'" . C   B 1 60  ? 61.045  81.178  111.896 1.00 92.53  ? 561  C   D "O4'" 1 
ATOM   2866  C  "C3'" . C   B 1 60  ? 62.730  82.463  112.916 1.00 88.73  ? 561  C   D "C3'" 1 
ATOM   2867  O  "O3'" . C   B 1 60  ? 63.794  83.380  112.669 1.00 89.85  ? 561  C   D "O3'" 1 
ATOM   2868  C  "C2'" . C   B 1 60  ? 61.406  83.180  113.122 1.00 91.25  ? 561  C   D "C2'" 1 
ATOM   2869  O  "O2'" . C   B 1 60  ? 61.230  84.251  112.219 1.00 94.73  ? 561  C   D "O2'" 1 
ATOM   2870  C  "C1'" . C   B 1 60  ? 60.406  82.063  112.807 1.00 93.08  ? 561  C   D "C1'" 1 
ATOM   2871  N  N1    . C   B 1 60  ? 60.016  81.293  113.999 1.00 91.05  ? 561  C   D N1    1 
ATOM   2872  C  C2    . C   B 1 60  ? 59.447  81.965  115.091 1.00 89.04  ? 561  C   D C2    1 
ATOM   2873  O  O2    . C   B 1 60  ? 59.242  83.185  115.012 1.00 90.92  ? 561  C   D O2    1 
ATOM   2874  N  N3    . C   B 1 60  ? 59.134  81.266  116.206 1.00 92.92  ? 561  C   D N3    1 
ATOM   2875  C  C4    . C   B 1 60  ? 59.356  79.948  116.254 1.00 91.84  ? 561  C   D C4    1 
ATOM   2876  N  N4    . C   B 1 60  ? 59.049  79.298  117.388 1.00 80.78  ? 561  C   D N4    1 
ATOM   2877  C  C5    . C   B 1 60  ? 59.906  79.236  115.148 1.00 91.24  ? 561  C   D C5    1 
ATOM   2878  C  C6    . C   B 1 60  ? 60.218  79.941  114.051 1.00 90.92  ? 561  C   D C6    1 
ATOM   2879  P  P     . C   B 1 61  ? 64.666  83.943  113.904 1.00 89.81  ? 562  C   D P     1 
ATOM   2880  O  OP1   . C   B 1 61  ? 65.795  84.732  113.353 1.00 90.54  ? 562  C   D OP1   1 
ATOM   2881  O  OP2   . C   B 1 61  ? 64.949  82.809  114.821 1.00 89.17  ? 562  C   D OP2   1 
ATOM   2882  O  "O5'" . C   B 1 61  ? 63.674  84.934  114.665 1.00 90.13  ? 562  C   D "O5'" 1 
ATOM   2883  C  "C5'" . C   B 1 61  ? 63.316  86.201  114.110 1.00 89.55  ? 562  C   D "C5'" 1 
ATOM   2884  C  "C4'" . C   B 1 61  ? 62.596  87.036  115.143 1.00 89.95  ? 562  C   D "C4'" 1 
ATOM   2885  O  "O4'" . C   B 1 61  ? 61.317  86.421  115.467 1.00 95.33  ? 562  C   D "O4'" 1 
ATOM   2886  C  "C3'" . C   B 1 61  ? 63.307  87.122  116.479 1.00 89.70  ? 562  C   D "C3'" 1 
ATOM   2887  O  "O3'" . C   B 1 61  ? 64.293  88.137  116.487 1.00 90.14  ? 562  C   D "O3'" 1 
ATOM   2888  C  "C2'" . C   B 1 61  ? 62.172  87.427  117.444 1.00 88.99  ? 562  C   D "C2'" 1 
ATOM   2889  O  "O2'" . C   B 1 61  ? 61.825  88.792  117.466 1.00 91.09  ? 562  C   D "O2'" 1 
ATOM   2890  C  "C1'" . C   B 1 61  ? 61.039  86.589  116.851 1.00 93.39  ? 562  C   D "C1'" 1 
ATOM   2891  N  N1    . C   B 1 61  ? 60.951  85.258  117.474 1.00 101.73 ? 562  C   D N1    1 
ATOM   2892  C  C2    . C   B 1 61  ? 60.261  85.126  118.681 1.00 99.70  ? 562  C   D C2    1 
ATOM   2893  O  O2    . C   B 1 61  ? 59.739  86.127  119.181 1.00 97.54  ? 562  C   D O2    1 
ATOM   2894  N  N3    . C   B 1 61  ? 60.184  83.910  119.273 1.00 101.01 ? 562  C   D N3    1 
ATOM   2895  C  C4    . C   B 1 61  ? 60.767  82.853  118.703 1.00 103.48 ? 562  C   D C4    1 
ATOM   2896  N  N4    . C   B 1 61  ? 60.667  81.672  119.324 1.00 102.70 ? 562  C   D N4    1 
ATOM   2897  C  C5    . C   B 1 61  ? 61.477  82.958  117.471 1.00 104.90 ? 562  C   D C5    1 
ATOM   2898  C  C6    . C   B 1 61  ? 61.539  84.167  116.894 1.00 105.99 ? 562  C   D C6    1 
ATOM   2899  P  P     . C   B 1 62  ? 65.446  88.095  117.600 1.00 99.33  ? 563  C   D P     1 
ATOM   2900  O  OP1   . C   B 1 62  ? 66.481  89.134  117.331 1.00 94.95  ? 563  C   D OP1   1 
ATOM   2901  O  OP2   . C   B 1 62  ? 65.846  86.667  117.715 1.00 93.67  ? 563  C   D OP2   1 
ATOM   2902  O  "O5'" . C   B 1 62  ? 64.683  88.487  118.941 1.00 98.76  ? 563  C   D "O5'" 1 
ATOM   2903  C  "C5'" . C   B 1 62  ? 64.178  89.801  119.138 1.00 92.51  ? 563  C   D "C5'" 1 
ATOM   2904  C  "C4'" . C   B 1 62  ? 63.615  89.928  120.527 1.00 91.32  ? 563  C   D "C4'" 1 
ATOM   2905  O  "O4'" . C   B 1 62  ? 62.449  89.071  120.648 1.00 90.07  ? 563  C   D "O4'" 1 
ATOM   2906  C  "C3'" . C   B 1 62  ? 64.542  89.450  121.630 1.00 92.02  ? 563  C   D "C3'" 1 
ATOM   2907  O  "O3'" . C   B 1 62  ? 65.470  90.457  122.014 1.00 96.48  ? 563  C   D "O3'" 1 
ATOM   2908  C  "C2'" . C   B 1 62  ? 63.565  89.116  122.749 1.00 97.35  ? 563  C   D "C2'" 1 
ATOM   2909  O  "O2'" . C   B 1 62  ? 63.148  90.244  123.491 1.00 94.90  ? 563  C   D "O2'" 1 
ATOM   2910  C  "C1'" . C   B 1 62  ? 62.387  88.535  121.961 1.00 99.41  ? 563  C   D "C1'" 1 
ATOM   2911  N  N1    . C   B 1 62  ? 62.445  87.067  121.868 1.00 103.91 ? 563  C   D N1    1 
ATOM   2912  C  C2    . C   B 1 62  ? 62.047  86.302  122.976 1.00 104.00 ? 563  C   D C2    1 
ATOM   2913  O  O2    . C   B 1 62  ? 61.656  86.886  124.003 1.00 100.47 ? 563  C   D O2    1 
ATOM   2914  N  N3    . C   B 1 62  ? 62.104  84.951  122.900 1.00 100.83 ? 563  C   D N3    1 
ATOM   2915  C  C4    . C   B 1 62  ? 62.540  84.363  121.782 1.00 100.02 ? 563  C   D C4    1 
ATOM   2916  N  N4    . C   B 1 62  ? 62.586  83.027  121.754 1.00 95.44  ? 563  C   D N4    1 
ATOM   2917  C  C5    . C   B 1 62  ? 62.949  85.116  120.643 1.00 102.30 ? 563  C   D C5    1 
ATOM   2918  C  C6    . C   B 1 62  ? 62.883  86.452  120.728 1.00 104.90 ? 563  C   D C6    1 
ATOM   2919  P  P     . C   B 1 63  ? 66.847  90.034  122.732 1.00 108.59 ? 564  C   D P     1 
ATOM   2920  O  OP1   . C   B 1 63  ? 67.748  91.217  122.798 1.00 108.02 ? 564  C   D OP1   1 
ATOM   2921  O  OP2   . C   B 1 63  ? 67.316  88.790  122.060 1.00 104.61 ? 564  C   D OP2   1 
ATOM   2922  O  "O5'" . C   B 1 63  ? 66.411  89.668  124.221 1.00 104.53 ? 564  C   D "O5'" 1 
ATOM   2923  C  "C5'" . C   B 1 63  ? 65.771  90.635  125.046 1.00 105.14 ? 564  C   D "C5'" 1 
ATOM   2924  C  "C4'" . C   B 1 63  ? 65.158  89.976  126.261 1.00 108.28 ? 564  C   D "C4'" 1 
ATOM   2925  O  "O4'" . C   B 1 63  ? 64.089  89.072  125.858 1.00 106.88 ? 564  C   D "O4'" 1 
ATOM   2926  C  "C3'" . C   B 1 63  ? 66.083  89.088  127.072 1.00 109.07 ? 564  C   D "C3'" 1 
ATOM   2927  O  "O3'" . C   B 1 63  ? 66.915  89.830  127.949 1.00 108.01 ? 564  C   D "O3'" 1 
ATOM   2928  C  "C2'" . C   B 1 63  ? 65.089  88.231  127.838 1.00 112.51 ? 564  C   D "C2'" 1 
ATOM   2929  O  "O2'" . C   B 1 63  ? 64.522  88.925  128.931 1.00 111.64 ? 564  C   D "O2'" 1 
ATOM   2930  C  "C1'" . C   B 1 63  ? 64.034  87.972  126.759 1.00 112.64 ? 564  C   D "C1'" 1 
ATOM   2931  N  N1    . C   B 1 63  ? 64.324  86.734  126.011 1.00 115.83 ? 564  C   D N1    1 
ATOM   2932  C  C2    . C   B 1 63  ? 64.052  85.498  126.619 1.00 116.88 ? 564  C   D C2    1 
ATOM   2933  O  O2    . C   B 1 63  ? 63.571  85.484  127.765 1.00 114.71 ? 564  C   D O2    1 
ATOM   2934  N  N3    . C   B 1 63  ? 64.324  84.354  125.945 1.00 116.71 ? 564  C   D N3    1 
ATOM   2935  C  C4    . C   B 1 63  ? 64.842  84.410  124.715 1.00 114.61 ? 564  C   D C4    1 
ATOM   2936  N  N4    . C   B 1 63  ? 65.088  83.256  124.087 1.00 109.48 ? 564  C   D N4    1 
ATOM   2937  C  C5    . C   B 1 63  ? 65.129  85.652  124.074 1.00 115.56 ? 564  C   D C5    1 
ATOM   2938  C  C6    . C   B 1 63  ? 64.855  86.779  124.751 1.00 115.03 ? 564  C   D C6    1 
ATOM   2939  P  P     . C   B 1 64  ? 68.396  89.291  128.275 1.00 115.09 ? 565  C   D P     1 
ATOM   2940  O  OP1   . C   B 1 64  ? 69.138  90.357  128.998 1.00 111.84 ? 565  C   D OP1   1 
ATOM   2941  O  OP2   . C   B 1 64  ? 68.954  88.734  127.014 1.00 111.52 ? 565  C   D OP2   1 
ATOM   2942  O  "O5'" . C   B 1 64  ? 68.145  88.077  129.276 1.00 110.91 ? 565  C   D "O5'" 1 
ATOM   2943  C  "C5'" . C   B 1 64  ? 67.290  88.237  130.402 1.00 106.89 ? 565  C   D "C5'" 1 
ATOM   2944  C  "C4'" . C   B 1 64  ? 66.854  86.893  130.927 1.00 98.60  ? 565  C   D "C4'" 1 
ATOM   2945  O  "O4'" . C   B 1 64  ? 66.053  86.207  129.933 1.00 90.86  ? 565  C   D "O4'" 1 
ATOM   2946  C  "C3'" . C   B 1 64  ? 67.973  85.918  131.206 1.00 94.77  ? 565  C   D "C3'" 1 
ATOM   2947  O  "O3'" . C   B 1 64  ? 68.516  86.117  132.484 1.00 99.75  ? 565  C   D "O3'" 1 
ATOM   2948  C  "C2'" . C   B 1 64  ? 67.246  84.589  131.186 1.00 94.22  ? 565  C   D "C2'" 1 
ATOM   2949  O  "O2'" . C   B 1 64  ? 66.557  84.335  132.386 1.00 90.97  ? 565  C   D "O2'" 1 
ATOM   2950  C  "C1'" . C   B 1 64  ? 66.255  84.809  130.052 1.00 97.80  ? 565  C   D "C1'" 1 
ATOM   2951  N  N1    . C   B 1 64  ? 66.782  84.295  128.782 1.00 105.31 ? 565  C   D N1    1 
ATOM   2952  C  C2    . C   B 1 64  ? 66.839  82.908  128.595 1.00 107.88 ? 565  C   D C2    1 
ATOM   2953  O  O2    . C   B 1 64  ? 66.474  82.163  129.519 1.00 107.42 ? 565  C   D O2    1 
ATOM   2954  N  N3    . C   B 1 64  ? 67.293  82.415  127.420 1.00 107.78 ? 565  C   D N3    1 
ATOM   2955  C  C4    . C   B 1 64  ? 67.693  83.252  126.458 1.00 109.91 ? 565  C   D C4    1 
ATOM   2956  N  N4    . C   B 1 64  ? 68.117  82.723  125.308 1.00 107.76 ? 565  C   D N4    1 
ATOM   2957  C  C5    . C   B 1 64  ? 67.669  84.669  126.632 1.00 109.06 ? 565  C   D C5    1 
ATOM   2958  C  C6    . C   B 1 64  ? 67.208  85.142  127.798 1.00 108.07 ? 565  C   D C6    1 
ATOM   2959  P  P     . U   B 1 65  ? 69.844  85.338  132.882 1.00 112.76 ? 566  U   D P     1 
ATOM   2960  O  OP1   . U   B 1 65  ? 70.059  85.509  134.335 1.00 112.04 ? 566  U   D OP1   1 
ATOM   2961  O  OP2   . U   B 1 65  ? 70.845  85.852  131.917 1.00 109.78 ? 566  U   D OP2   1 
ATOM   2962  O  "O5'" . U   B 1 65  ? 69.538  83.797  132.560 1.00 120.28 ? 566  U   D "O5'" 1 
ATOM   2963  C  "C5'" . U   B 1 65  ? 68.846  82.951  133.493 1.00 116.97 ? 566  U   D "C5'" 1 
ATOM   2964  C  "C4'" . U   B 1 65  ? 69.032  81.484  133.135 1.00 109.15 ? 566  U   D "C4'" 1 
ATOM   2965  O  "O4'" . U   B 1 65  ? 68.371  81.177  131.877 1.00 107.03 ? 566  U   D "O4'" 1 
ATOM   2966  C  "C3'" . U   B 1 65  ? 70.461  81.035  132.904 1.00 102.17 ? 566  U   D "C3'" 1 
ATOM   2967  O  "O3'" . U   B 1 65  ? 71.134  80.770  134.118 1.00 97.22  ? 566  U   D "O3'" 1 
ATOM   2968  C  "C2'" . U   B 1 65  ? 70.264  79.767  132.095 1.00 106.68 ? 566  U   D "C2'" 1 
ATOM   2969  O  "O2'" . U   B 1 65  ? 69.901  78.672  132.910 1.00 111.36 ? 566  U   D "O2'" 1 
ATOM   2970  C  "C1'" . U   B 1 65  ? 69.103  80.173  131.189 1.00 111.60 ? 566  U   D "C1'" 1 
ATOM   2971  N  N1    . U   B 1 65  ? 69.577  80.738  129.919 1.00 117.58 ? 566  U   D N1    1 
ATOM   2972  C  C2    . U   B 1 65  ? 69.838  79.863  128.879 1.00 121.39 ? 566  U   D C2    1 
ATOM   2973  O  O2    . U   B 1 65  ? 69.696  78.652  128.977 1.00 122.75 ? 566  U   D O2    1 
ATOM   2974  N  N3    . U   B 1 65  ? 70.277  80.457  127.722 1.00 123.53 ? 566  U   D N3    1 
ATOM   2975  C  C4    . U   B 1 65  ? 70.485  81.804  127.505 1.00 121.01 ? 566  U   D C4    1 
ATOM   2976  O  O4    . U   B 1 65  ? 70.876  82.185  126.402 1.00 119.82 ? 566  U   D O4    1 
ATOM   2977  C  C5    . U   B 1 65  ? 70.200  82.640  128.630 1.00 118.20 ? 566  U   D C5    1 
ATOM   2978  C  C6    . U   B 1 65  ? 69.763  82.092  129.768 1.00 119.12 ? 566  U   D C6    1 
ATOM   2979  P  P     . G   B 1 66  ? 72.735  80.865  134.161 1.00 106.71 ? 567  G   D P     1 
ATOM   2980  O  OP1   . G   B 1 66  ? 73.234  80.483  135.510 1.00 105.61 ? 567  G   D OP1   1 
ATOM   2981  O  OP2   . G   B 1 66  ? 73.101  82.181  133.586 1.00 101.61 ? 567  G   D OP2   1 
ATOM   2982  O  "O5'" . G   B 1 66  ? 73.188  79.731  133.147 1.00 103.70 ? 567  G   D "O5'" 1 
ATOM   2983  C  "C5'" . G   B 1 66  ? 72.846  78.379  133.395 1.00 99.43  ? 567  G   D "C5'" 1 
ATOM   2984  C  "C4'" . G   B 1 66  ? 73.297  77.519  132.254 1.00 93.26  ? 567  G   D "C4'" 1 
ATOM   2985  O  "O4'" . G   B 1 66  ? 72.471  77.769  131.083 1.00 98.41  ? 567  G   D "O4'" 1 
ATOM   2986  C  "C3'" . G   B 1 66  ? 74.691  77.824  131.756 1.00 85.17  ? 567  G   D "C3'" 1 
ATOM   2987  O  "O3'" . G   B 1 66  ? 75.699  77.295  132.597 1.00 76.73  ? 567  G   D "O3'" 1 
ATOM   2988  C  "C2'" . G   B 1 66  ? 74.649  77.183  130.382 1.00 95.39  ? 567  G   D "C2'" 1 
ATOM   2989  O  "O2'" . G   B 1 66  ? 74.691  75.772  130.451 1.00 102.59 ? 567  G   D "O2'" 1 
ATOM   2990  C  "C1'" . G   B 1 66  ? 73.262  77.620  129.911 1.00 99.08  ? 567  G   D "C1'" 1 
ATOM   2991  N  N9    . G   B 1 66  ? 73.319  78.904  129.217 1.00 99.59  ? 567  G   D N9    1 
ATOM   2992  C  C8    . G   B 1 66  ? 72.979  80.137  129.719 1.00 98.82  ? 567  G   D C8    1 
ATOM   2993  N  N7    . G   B 1 66  ? 73.163  81.107  128.864 1.00 96.74  ? 567  G   D N7    1 
ATOM   2994  C  C5    . G   B 1 66  ? 73.650  80.475  127.726 1.00 98.07  ? 567  G   D C5    1 
ATOM   2995  C  C6    . G   B 1 66  ? 74.037  81.012  126.464 1.00 92.10  ? 567  G   D C6    1 
ATOM   2996  O  O6    . G   B 1 66  ? 74.032  82.188  126.090 1.00 84.18  ? 567  G   D O6    1 
ATOM   2997  N  N1    . G   B 1 66  ? 74.468  80.016  125.596 1.00 89.59  ? 567  G   D N1    1 
ATOM   2998  C  C2    . G   B 1 66  ? 74.525  78.681  125.892 1.00 92.13  ? 567  G   D C2    1 
ATOM   2999  N  N2    . G   B 1 66  ? 74.966  77.884  124.915 1.00 88.41  ? 567  G   D N2    1 
ATOM   3000  N  N3    . G   B 1 66  ? 74.173  78.166  127.061 1.00 96.34  ? 567  G   D N3    1 
ATOM   3001  C  C4    . G   B 1 66  ? 73.747  79.115  127.924 1.00 99.31  ? 567  G   D C4    1 
ATOM   3002  P  P     . G   B 1 67  ? 77.156  77.974  132.588 1.00 77.97  ? 568  G   D P     1 
ATOM   3003  O  OP1   . G   B 1 67  ? 78.078  77.339  133.559 1.00 71.64  ? 568  G   D OP1   1 
ATOM   3004  O  OP2   . G   B 1 67  ? 76.911  79.431  132.667 1.00 82.44  ? 568  G   D OP2   1 
ATOM   3005  O  "O5'" . G   B 1 67  ? 77.701  77.607  131.139 1.00 81.52  ? 568  G   D "O5'" 1 
ATOM   3006  C  "C5'" . G   B 1 67  ? 77.883  76.246  130.771 1.00 76.31  ? 568  G   D "C5'" 1 
ATOM   3007  C  "C4'" . G   B 1 67  ? 78.380  76.134  129.352 1.00 70.72  ? 568  G   D "C4'" 1 
ATOM   3008  O  "O4'" . G   B 1 67  ? 77.342  76.557  128.428 1.00 75.26  ? 568  G   D "O4'" 1 
ATOM   3009  C  "C3'" . G   B 1 67  ? 79.565  76.997  128.979 1.00 62.39  ? 568  G   D "C3'" 1 
ATOM   3010  O  "O3'" . G   B 1 67  ? 80.787  76.441  129.427 1.00 65.20  ? 568  G   D "O3'" 1 
ATOM   3011  C  "C2'" . G   B 1 67  ? 79.456  77.009  127.465 1.00 65.09  ? 568  G   D "C2'" 1 
ATOM   3012  O  "O2'" . G   B 1 67  ? 79.868  75.806  126.869 1.00 70.64  ? 568  G   D "O2'" 1 
ATOM   3013  C  "C1'" . G   B 1 67  ? 77.945  77.143  127.285 1.00 79.33  ? 568  G   D "C1'" 1 
ATOM   3014  N  N9    . G   B 1 67  ? 77.573  78.553  127.228 1.00 91.89  ? 568  G   D N9    1 
ATOM   3015  C  C8    . G   B 1 67  ? 76.981  79.307  128.214 1.00 87.63  ? 568  G   D C8    1 
ATOM   3016  N  N7    . G   B 1 67  ? 76.826  80.556  127.876 1.00 84.01  ? 568  G   D N7    1 
ATOM   3017  C  C5    . G   B 1 67  ? 77.337  80.630  126.587 1.00 84.71  ? 568  G   D C5    1 
ATOM   3018  C  C6    . G   B 1 67  ? 77.456  81.734  125.704 1.00 78.62  ? 568  G   D C6    1 
ATOM   3019  O  O6    . G   B 1 67  ? 77.136  82.909  125.894 1.00 64.34  ? 568  G   D O6    1 
ATOM   3020  N  N1    . G   B 1 67  ? 78.027  81.359  124.491 1.00 80.04  ? 568  G   D N1    1 
ATOM   3021  C  C2    . G   B 1 67  ? 78.436  80.090  124.165 1.00 81.48  ? 568  G   D C2    1 
ATOM   3022  N  N2    . G   B 1 67  ? 78.951  79.923  122.934 1.00 75.28  ? 568  G   D N2    1 
ATOM   3023  N  N3    . G   B 1 67  ? 78.344  79.060  124.983 1.00 88.12  ? 568  G   D N3    1 
ATOM   3024  C  C4    . G   B 1 67  ? 77.787  79.399  126.168 1.00 88.82  ? 568  G   D C4    1 
ATOM   3025  P  P     . G   B 1 68  ? 82.027  77.414  129.739 1.00 79.19  ? 569  G   D P     1 
ATOM   3026  O  OP1   . G   B 1 68  ? 83.138  76.653  130.381 1.00 87.19  ? 569  G   D OP1   1 
ATOM   3027  O  OP2   . G   B 1 68  ? 81.427  78.568  130.455 1.00 87.08  ? 569  G   D OP2   1 
ATOM   3028  O  "O5'" . G   B 1 68  ? 82.517  77.894  128.299 1.00 74.79  ? 569  G   D "O5'" 1 
ATOM   3029  C  "C5'" . G   B 1 68  ? 82.844  76.947  127.279 1.00 66.13  ? 569  G   D "C5'" 1 
ATOM   3030  C  "C4'" . G   B 1 68  ? 83.022  77.635  125.941 1.00 57.27  ? 569  G   D "C4'" 1 
ATOM   3031  O  "O4'" . G   B 1 68  ? 81.746  78.149  125.465 1.00 63.72  ? 569  G   D "O4'" 1 
ATOM   3032  C  "C3'" . G   B 1 68  ? 83.933  78.849  125.932 1.00 50.63  ? 569  G   D "C3'" 1 
ATOM   3033  O  "O3'" . G   B 1 68  ? 85.293  78.490  125.818 1.00 52.36  ? 569  G   D "O3'" 1 
ATOM   3034  C  "C2'" . G   B 1 68  ? 83.472  79.597  124.689 1.00 53.95  ? 569  G   D "C2'" 1 
ATOM   3035  O  "O2'" . G   B 1 68  ? 84.051  79.121  123.499 1.00 49.13  ? 569  G   D "O2'" 1 
ATOM   3036  C  "C1'" . G   B 1 68  ? 81.964  79.344  124.716 1.00 62.84  ? 569  G   D "C1'" 1 
ATOM   3037  N  N9    . G   B 1 68  ? 81.264  80.454  125.368 1.00 74.93  ? 569  G   D N9    1 
ATOM   3038  C  C8    . G   B 1 68  ? 80.638  80.444  126.594 1.00 73.25  ? 569  G   D C8    1 
ATOM   3039  N  N7    . G   B 1 68  ? 80.131  81.602  126.920 1.00 74.52  ? 569  G   D N7    1 
ATOM   3040  C  C5    . G   B 1 68  ? 80.438  82.431  125.846 1.00 71.64  ? 569  G   D C5    1 
ATOM   3041  C  C6    . G   B 1 68  ? 80.146  83.816  125.626 1.00 68.54  ? 569  G   D C6    1 
ATOM   3042  O  O6    . G   B 1 68  ? 79.554  84.613  126.371 1.00 54.02  ? 569  G   D O6    1 
ATOM   3043  N  N1    . G   B 1 68  ? 80.625  84.246  124.394 1.00 59.55  ? 569  G   D N1    1 
ATOM   3044  C  C2    . G   B 1 68  ? 81.294  83.460  123.491 1.00 55.23  ? 569  G   D C2    1 
ATOM   3045  N  N2    . G   B 1 68  ? 81.657  84.060  122.360 1.00 48.18  ? 569  G   D N2    1 
ATOM   3046  N  N3    . G   B 1 68  ? 81.582  82.183  123.683 1.00 59.91  ? 569  G   D N3    1 
ATOM   3047  C  C4    . G   B 1 68  ? 81.126  81.737  124.873 1.00 68.13  ? 569  G   D C4    1 
ATOM   3048  P  P     . G   B 1 69  ? 86.429  79.534  126.259 1.00 69.59  ? 570  G   D P     1 
ATOM   3049  O  OP1   . G   B 1 69  ? 87.740  78.830  126.306 1.00 72.50  ? 570  G   D OP1   1 
ATOM   3050  O  OP2   . G   B 1 69  ? 85.911  80.192  127.490 1.00 65.64  ? 570  G   D OP2   1 
ATOM   3051  O  "O5'" . G   B 1 69  ? 86.466  80.641  125.107 1.00 67.31  ? 570  G   D "O5'" 1 
ATOM   3052  C  "C5'" . G   B 1 69  ? 86.600  80.305  123.730 1.00 59.56  ? 570  G   D "C5'" 1 
ATOM   3053  C  "C4'" . G   B 1 69  ? 86.449  81.549  122.872 1.00 64.61  ? 570  G   D "C4'" 1 
ATOM   3054  O  "O4'" . G   B 1 69  ? 85.078  82.015  122.946 1.00 63.97  ? 570  G   D "O4'" 1 
ATOM   3055  C  "C3'" . G   B 1 69  ? 87.273  82.765  123.288 1.00 62.93  ? 570  G   D "C3'" 1 
ATOM   3056  O  "O3'" . G   B 1 69  ? 88.585  82.748  122.743 1.00 72.99  ? 570  G   D "O3'" 1 
ATOM   3057  C  "C2'" . G   B 1 69  ? 86.487  83.926  122.689 1.00 60.29  ? 570  G   D "C2'" 1 
ATOM   3058  O  "O2'" . G   B 1 69  ? 86.799  84.211  121.341 1.00 53.09  ? 570  G   D "O2'" 1 
ATOM   3059  C  "C1'" . G   B 1 69  ? 85.049  83.433  122.827 1.00 61.74  ? 570  G   D "C1'" 1 
ATOM   3060  N  N9    . G   B 1 69  ? 84.404  83.988  124.012 1.00 66.88  ? 570  G   D N9    1 
ATOM   3061  C  C8    . G   B 1 69  ? 84.137  83.331  125.188 1.00 63.60  ? 570  G   D C8    1 
ATOM   3062  N  N7    . G   B 1 69  ? 83.549  84.087  126.072 1.00 67.95  ? 570  G   D N7    1 
ATOM   3063  C  C5    . G   B 1 69  ? 83.424  85.321  125.444 1.00 64.52  ? 570  G   D C5    1 
ATOM   3064  C  C6    . G   B 1 69  ? 82.866  86.539  125.914 1.00 55.34  ? 570  G   D C6    1 
ATOM   3065  O  O6    . G   B 1 69  ? 82.372  86.783  127.016 1.00 37.98  ? 570  G   D O6    1 
ATOM   3066  N  N1    . G   B 1 69  ? 82.927  87.531  124.947 1.00 50.31  ? 570  G   D N1    1 
ATOM   3067  C  C2    . G   B 1 69  ? 83.456  87.379  123.697 1.00 43.07  ? 570  G   D C2    1 
ATOM   3068  N  N2    . G   B 1 69  ? 83.392  88.453  122.909 1.00 41.04  ? 570  G   D N2    1 
ATOM   3069  N  N3    . G   B 1 69  ? 83.998  86.258  123.252 1.00 50.10  ? 570  G   D N3    1 
ATOM   3070  C  C4    . G   B 1 69  ? 83.945  85.276  124.171 1.00 58.16  ? 570  G   D C4    1 
ATOM   3071  P  P     . U   B 1 70  ? 89.780  83.518  123.504 1.00 81.06  ? 571  U   D P     1 
ATOM   3072  O  OP1   . U   B 1 70  ? 91.051  83.267  122.781 1.00 91.80  ? 571  U   D OP1   1 
ATOM   3073  O  OP2   . U   B 1 70  ? 89.651  83.113  124.925 1.00 80.46  ? 571  U   D OP2   1 
ATOM   3074  O  "O5'" . U   B 1 70  ? 89.464  85.071  123.344 1.00 70.65  ? 571  U   D "O5'" 1 
ATOM   3075  C  "C5'" . U   B 1 70  ? 89.361  85.667  122.054 1.00 77.31  ? 571  U   D "C5'" 1 
ATOM   3076  C  "C4'" . U   B 1 70  ? 88.769  87.058  122.162 1.00 77.58  ? 571  U   D "C4'" 1 
ATOM   3077  O  "O4'" . U   B 1 70  ? 87.401  86.974  122.645 1.00 75.51  ? 571  U   D "O4'" 1 
ATOM   3078  C  "C3'" . U   B 1 70  ? 89.461  88.002  123.134 1.00 72.12  ? 571  U   D "C3'" 1 
ATOM   3079  O  "O3'" . U   B 1 70  ? 90.577  88.628  122.505 1.00 79.97  ? 571  U   D "O3'" 1 
ATOM   3080  C  "C2'" . U   B 1 70  ? 88.353  88.995  123.473 1.00 64.68  ? 571  U   D "C2'" 1 
ATOM   3081  O  "O2'" . U   B 1 70  ? 88.190  90.006  122.506 1.00 65.22  ? 571  U   D "O2'" 1 
ATOM   3082  C  "C1'" . U   B 1 70  ? 87.116  88.097  123.462 1.00 63.72  ? 571  U   D "C1'" 1 
ATOM   3083  N  N1    . U   B 1 70  ? 86.713  87.608  124.785 1.00 62.57  ? 571  U   D N1    1 
ATOM   3084  C  C2    . U   B 1 70  ? 86.096  88.493  125.643 1.00 60.83  ? 571  U   D C2    1 
ATOM   3085  O  O2    . U   B 1 70  ? 85.910  89.662  125.365 1.00 57.30  ? 571  U   D O2    1 
ATOM   3086  N  N3    . U   B 1 70  ? 85.702  87.958  126.841 1.00 63.03  ? 571  U   D N3    1 
ATOM   3087  C  C4    . U   B 1 70  ? 85.859  86.654  127.257 1.00 69.40  ? 571  U   D C4    1 
ATOM   3088  O  O4    . U   B 1 70  ? 85.365  86.294  128.334 1.00 71.01  ? 571  U   D O4    1 
ATOM   3089  C  C5    . U   B 1 70  ? 86.528  85.809  126.317 1.00 63.46  ? 571  U   D C5    1 
ATOM   3090  C  C6    . U   B 1 70  ? 86.925  86.306  125.147 1.00 61.79  ? 571  U   D C6    1 
ATOM   3091  P  P     . C   B 1 71  ? 91.601  89.541  123.370 1.00 85.55  ? 572  C   D P     1 
ATOM   3092  O  OP1   . C   B 1 71  ? 92.862  89.685  122.601 1.00 85.60  ? 572  C   D OP1   1 
ATOM   3093  O  OP2   . C   B 1 71  ? 91.656  89.044  124.778 1.00 71.14  ? 572  C   D OP2   1 
ATOM   3094  O  "O5'" . C   B 1 71  ? 90.940  90.983  123.371 1.00 66.95  ? 572  C   D "O5'" 1 
ATOM   3095  C  "C5'" . C   B 1 71  ? 91.515  92.004  124.143 1.00 73.08  ? 572  C   D "C5'" 1 
ATOM   3096  C  "C4'" . C   B 1 71  ? 90.446  92.882  124.712 1.00 78.46  ? 572  C   D "C4'" 1 
ATOM   3097  O  "O4'" . C   B 1 71  ? 89.240  92.115  124.935 1.00 78.91  ? 572  C   D "O4'" 1 
ATOM   3098  C  "C3'" . C   B 1 71  ? 90.766  93.416  126.091 1.00 88.08  ? 572  C   D "C3'" 1 
ATOM   3099  O  "O3'" . C   B 1 71  ? 91.638  94.522  126.029 1.00 99.80  ? 572  C   D "O3'" 1 
ATOM   3100  C  "C2'" . C   B 1 71  ? 89.396  93.795  126.617 1.00 78.59  ? 572  C   D "C2'" 1 
ATOM   3101  O  "O2'" . C   B 1 71  ? 88.958  95.031  126.091 1.00 79.14  ? 572  C   D "O2'" 1 
ATOM   3102  C  "C1'" . C   B 1 71  ? 88.549  92.656  126.053 1.00 76.08  ? 572  C   D "C1'" 1 
ATOM   3103  N  N1    . C   B 1 71  ? 88.313  91.577  127.017 1.00 67.45  ? 572  C   D N1    1 
ATOM   3104  C  C2    . C   B 1 71  ? 87.344  91.765  128.015 1.00 57.98  ? 572  C   D C2    1 
ATOM   3105  O  O2    . C   B 1 71  ? 86.768  92.861  128.092 1.00 48.77  ? 572  C   D O2    1 
ATOM   3106  N  N3    . C   B 1 71  ? 87.065  90.751  128.863 1.00 50.43  ? 572  C   D N3    1 
ATOM   3107  C  C4    . C   B 1 71  ? 87.715  89.591  128.750 1.00 58.92  ? 572  C   D C4    1 
ATOM   3108  N  N4    . C   B 1 71  ? 87.379  88.606  129.583 1.00 42.17  ? 572  C   D N4    1 
ATOM   3109  C  C5    . C   B 1 71  ? 88.735  89.386  127.769 1.00 61.21  ? 572  C   D C5    1 
ATOM   3110  C  C6    . C   B 1 71  ? 89.001  90.399  126.933 1.00 63.58  ? 572  C   D C6    1 
ATOM   3111  P  P     . A   B 1 72  ? 92.998  94.473  126.865 1.00 104.90 ? 573  A   D P     1 
ATOM   3112  O  OP1   . A   B 1 72  ? 93.395  93.034  126.976 1.00 93.16  ? 573  A   D OP1   1 
ATOM   3113  O  OP2   . A   B 1 72  ? 92.795  95.284  128.091 1.00 94.74  ? 573  A   D OP2   1 
ATOM   3114  O  "O5'" . A   B 1 72  ? 94.036  95.220  125.925 1.00 103.51 ? 573  A   D "O5'" 1 
ATOM   3115  C  "C5'" . A   B 1 72  ? 94.796  94.507  124.955 1.00 96.58  ? 573  A   D "C5'" 1 
ATOM   3116  C  "C4'" . A   B 1 72  ? 96.259  94.729  125.215 1.00 94.18  ? 573  A   D "C4'" 1 
ATOM   3117  O  "O4'" . A   B 1 72  ? 96.761  93.630  126.021 1.00 88.55  ? 573  A   D "O4'" 1 
ATOM   3118  C  "C3'" . A   B 1 72  ? 97.105  94.725  123.958 1.00 95.22  ? 573  A   D "C3'" 1 
ATOM   3119  O  "O3'" . A   B 1 72  ? 97.740  95.954  123.620 1.00 89.13  ? 573  A   D "O3'" 1 
ATOM   3120  C  "C2'" . A   B 1 72  ? 97.735  93.338  123.834 1.00 94.65  ? 573  A   D "C2'" 1 
ATOM   3121  O  "O2'" . A   B 1 72  ? 99.110  93.378  123.515 1.00 105.34 ? 573  A   D "O2'" 1 
ATOM   3122  C  "C1'" . A   B 1 72  ? 97.633  92.810  125.264 1.00 88.76  ? 573  A   D "C1'" 1 
ATOM   3123  N  N9    . A   B 1 72  ? 97.193  91.419  125.369 1.00 83.91  ? 573  A   D N9    1 
ATOM   3124  C  C8    . A   B 1 72  ? 95.914  90.921  125.469 1.00 81.86  ? 573  A   D C8    1 
ATOM   3125  N  N7    . A   B 1 72  ? 95.862  89.611  125.550 1.00 72.55  ? 573  A   D N7    1 
ATOM   3126  C  C5    . A   B 1 72  ? 97.194  89.219  125.498 1.00 71.53  ? 573  A   D C5    1 
ATOM   3127  C  C6    . A   B 1 72  ? 97.816  87.952  125.525 1.00 75.58  ? 573  A   D C6    1 
ATOM   3128  N  N6    . A   B 1 72  ? 97.149  86.797  125.613 1.00 73.53  ? 573  A   D N6    1 
ATOM   3129  N  N1    . A   B 1 72  ? 99.167  87.914  125.452 1.00 77.40  ? 573  A   D N1    1 
ATOM   3130  C  C2    . A   B 1 72  ? 99.838  89.070  125.356 1.00 77.22  ? 573  A   D C2    1 
ATOM   3131  N  N3    . A   B 1 72  ? 99.369  90.317  125.313 1.00 81.39  ? 573  A   D N3    1 
ATOM   3132  C  C4    . A   B 1 72  ? 98.024  90.323  125.389 1.00 79.01  ? 573  A   D C4    1 
ATOM   3133  P  P     . C   B 1 73  ? 98.896  96.534  124.569 1.00 87.22  ? 574  C   D P     1 
ATOM   3134  O  OP1   . C   B 1 73  ? 99.054  95.635  125.739 1.00 92.67  ? 574  C   D OP1   1 
ATOM   3135  O  OP2   . C   B 1 73  ? 98.584  97.966  124.793 1.00 98.86  ? 574  C   D OP2   1 
ATOM   3136  O  "O5'" . C   B 1 73  ? 100.206 96.446  123.667 1.00 91.60  ? 574  C   D "O5'" 1 
ATOM   3137  C  "C5'" . C   B 1 73  ? 100.093 96.263  122.264 1.00 84.88  ? 574  C   D "C5'" 1 
ATOM   3138  C  "C4'" . C   B 1 73  ? 101.327 95.597  121.712 1.00 80.81  ? 574  C   D "C4'" 1 
ATOM   3139  O  "O4'" . C   B 1 73  ? 102.348 96.601  121.455 1.00 81.17  ? 574  C   D "O4'" 1 
ATOM   3140  C  "C3'" . C   B 1 73  ? 101.932 94.659  122.743 1.00 74.96  ? 574  C   D "C3'" 1 
ATOM   3141  O  "O3'" . C   B 1 73  ? 101.898 93.263  122.472 1.00 80.01  ? 574  C   D "O3'" 1 
ATOM   3142  C  "C2'" . C   B 1 73  ? 103.092 95.404  123.400 1.00 74.18  ? 574  C   D "C2'" 1 
ATOM   3143  O  "O2'" . C   B 1 73  ? 104.246 94.642  123.645 1.00 67.72  ? 574  C   D "O2'" 1 
ATOM   3144  C  "C1'" . C   B 1 73  ? 103.449 96.414  122.319 1.00 77.57  ? 574  C   D "C1'" 1 
ATOM   3145  N  N1    . C   B 1 73  ? 103.956 97.703  122.788 1.00 83.13  ? 574  C   D N1    1 
ATOM   3146  C  C2    . C   B 1 73  ? 105.139 98.195  122.214 1.00 84.96  ? 574  C   D C2    1 
ATOM   3147  O  O2    . C   B 1 73  ? 105.665 97.568  121.279 1.00 75.75  ? 574  C   D O2    1 
ATOM   3148  N  N3    . C   B 1 73  ? 105.673 99.339  122.684 1.00 90.51  ? 574  C   D N3    1 
ATOM   3149  C  C4    . C   B 1 73  ? 105.071 99.997  123.676 1.00 93.28  ? 574  C   D C4    1 
ATOM   3150  N  N4    . C   B 1 73  ? 105.654 101.114 124.126 1.00 98.09  ? 574  C   D N4    1 
ATOM   3151  C  C5    . C   B 1 73  ? 103.848 99.537  124.255 1.00 92.69  ? 574  C   D C5    1 
ATOM   3152  C  C6    . C   B 1 73  ? 103.329 98.397  123.781 1.00 85.23  ? 574  C   D C6    1 
ATOM   3153  P  P     . C   B 1 74  ? 103.222 92.499  121.974 1.00 84.44  ? 575  C   D P     1 
ATOM   3154  O  OP1   . C   B 1 74  ? 104.156 92.275  123.103 1.00 85.67  ? 575  C   D OP1   1 
ATOM   3155  O  OP2   . C   B 1 74  ? 103.700 93.181  120.751 1.00 90.42  ? 575  C   D OP2   1 
ATOM   3156  O  "O5'" . C   B 1 74  ? 102.661 91.089  121.533 1.00 83.87  ? 575  C   D "O5'" 1 
ATOM   3157  C  "C5'" . C   B 1 74  ? 101.512 90.552  122.159 1.00 88.30  ? 575  C   D "C5'" 1 
ATOM   3158  C  "C4'" . C   B 1 74  ? 101.288 89.160  121.656 1.00 96.63  ? 575  C   D "C4'" 1 
ATOM   3159  O  "O4'" . C   B 1 74  ? 100.406 88.434  122.538 1.00 97.11  ? 575  C   D "O4'" 1 
ATOM   3160  C  "C3'" . C   B 1 74  ? 100.653 89.005  120.285 1.00 97.06  ? 575  C   D "C3'" 1 
ATOM   3161  O  "O3'" . C   B 1 74  ? 101.626 89.277  119.265 1.00 95.30  ? 575  C   D "O3'" 1 
ATOM   3162  C  "C2'" . C   B 1 74  ? 100.232 87.539  120.341 1.00 96.36  ? 575  C   D "C2'" 1 
ATOM   3163  O  "O2'" . C   B 1 74  ? 101.341 86.685  120.124 1.00 93.32  ? 575  C   D "O2'" 1 
ATOM   3164  C  "C1'" . C   B 1 74  ? 99.788  87.397  121.806 1.00 95.68  ? 575  C   D "C1'" 1 
ATOM   3165  N  N1    . C   B 1 74  ? 98.340  87.483  122.026 1.00 94.81  ? 575  C   D N1    1 
ATOM   3166  C  C2    . C   B 1 74  ? 97.629  86.298  122.253 1.00 100.17 ? 575  C   D C2    1 
ATOM   3167  O  O2    . C   B 1 74  ? 98.248  85.220  122.262 1.00 102.90 ? 575  C   D O2    1 
ATOM   3168  N  N3    . C   B 1 74  ? 96.294  86.353  122.459 1.00 99.95  ? 575  C   D N3    1 
ATOM   3169  C  C4    . C   B 1 74  ? 95.668  87.532  122.447 1.00 97.48  ? 575  C   D C4    1 
ATOM   3170  N  N4    . C   B 1 74  ? 94.349  87.537  122.665 1.00 93.06  ? 575  C   D N4    1 
ATOM   3171  C  C5    . C   B 1 74  ? 96.368  88.759  122.215 1.00 93.14  ? 575  C   D C5    1 
ATOM   3172  C  C6    . C   B 1 74  ? 97.692  88.688  122.012 1.00 89.31  ? 575  C   D C6    1 
ATOM   3173  P  P     . A   B 1 75  ? 101.219 89.205  117.704 1.00 88.73  ? 576  A   D P     1 
ATOM   3174  O  OP1   . A   B 1 75  ? 102.303 89.848  116.921 1.00 76.03  ? 576  A   D OP1   1 
ATOM   3175  O  OP2   . A   B 1 75  ? 99.812  89.679  117.545 1.00 69.50  ? 576  A   D OP2   1 
ATOM   3176  O  "O5'" . A   B 1 75  ? 101.292 87.646  117.390 1.00 82.04  ? 576  A   D "O5'" 1 
ATOM   3177  C  "C5'" . A   B 1 75  ? 100.691 87.116  116.227 1.00 82.69  ? 576  A   D "C5'" 1 
ATOM   3178  C  "C4'" . A   B 1 75  ? 99.941  85.854  116.563 1.00 83.21  ? 576  A   D "C4'" 1 
ATOM   3179  O  "O4'" . A   B 1 75  ? 99.432  85.924  117.917 1.00 84.69  ? 576  A   D "O4'" 1 
ATOM   3180  C  "C3'" . A   B 1 75  ? 98.717  85.635  115.696 1.00 78.52  ? 576  A   D "C3'" 1 
ATOM   3181  O  "O3'" . A   B 1 75  ? 99.128  85.134  114.422 1.00 80.89  ? 576  A   D "O3'" 1 
ATOM   3182  C  "C2'" . A   B 1 75  ? 97.822  84.783  116.589 1.00 75.81  ? 576  A   D "C2'" 1 
ATOM   3183  O  "O2'" . A   B 1 75  ? 98.141  83.410  116.555 1.00 65.64  ? 576  A   D "O2'" 1 
ATOM   3184  C  "C1'" . A   B 1 75  ? 98.130  85.365  117.974 1.00 79.48  ? 576  A   D "C1'" 1 
ATOM   3185  N  N9    . A   B 1 75  ? 97.214  86.435  118.351 1.00 78.82  ? 576  A   D N9    1 
ATOM   3186  C  C8    . A   B 1 75  ? 97.437  87.788  118.252 1.00 80.81  ? 576  A   D C8    1 
ATOM   3187  N  N7    . A   B 1 75  ? 96.403  88.519  118.588 1.00 79.12  ? 576  A   D N7    1 
ATOM   3188  C  C5    . A   B 1 75  ? 95.438  87.586  118.944 1.00 84.76  ? 576  A   D C5    1 
ATOM   3189  C  C6    . A   B 1 75  ? 94.097  87.720  119.358 1.00 86.55  ? 576  A   D C6    1 
ATOM   3190  N  N6    . A   B 1 75  ? 93.465  88.895  119.451 1.00 79.60  ? 576  A   D N6    1 
ATOM   3191  N  N1    . A   B 1 75  ? 93.415  86.588  119.658 1.00 88.75  ? 576  A   D N1    1 
ATOM   3192  C  C2    . A   B 1 75  ? 94.041  85.410  119.524 1.00 86.71  ? 576  A   D C2    1 
ATOM   3193  N  N3    . A   B 1 75  ? 95.288  85.156  119.118 1.00 85.26  ? 576  A   D N3    1 
ATOM   3194  C  C4    . A   B 1 75  ? 95.938  86.299  118.837 1.00 84.51  ? 576  A   D C4    1 
ATOM   3195  N  N     . MET C 2 1   ? 35.013  83.870  29.794  1.00 73.58  ? 1    MET A N     1 
ATOM   3196  C  CA    . MET C 2 1   ? 34.357  82.560  30.134  1.00 74.31  ? 1    MET A CA    1 
ATOM   3197  C  C     . MET C 2 1   ? 34.032  82.383  31.634  1.00 66.92  ? 1    MET A C     1 
ATOM   3198  O  O     . MET C 2 1   ? 33.266  83.173  32.216  1.00 64.45  ? 1    MET A O     1 
ATOM   3199  C  CB    . MET C 2 1   ? 35.247  81.401  29.674  1.00 80.80  ? 1    MET A CB    1 
ATOM   3200  C  CG    . MET C 2 1   ? 36.693  81.550  30.115  1.00 87.92  ? 1    MET A CG    1 
ATOM   3201  S  SD    . MET C 2 1   ? 37.463  79.969  30.436  1.00 98.40  ? 1    MET A SD    1 
ATOM   3202  C  CE    . MET C 2 1   ? 38.237  80.298  31.987  1.00 97.04  ? 1    MET A CE    1 
ATOM   3203  N  N     . VAL C 2 2   ? 34.609  81.343  32.244  1.00 45.72  ? 2    VAL A N     1 
ATOM   3204  C  CA    . VAL C 2 2   ? 34.379  81.056  33.646  1.00 30.42  ? 2    VAL A CA    1 
ATOM   3205  C  C     . VAL C 2 2   ? 35.642  80.629  34.378  1.00 29.30  ? 2    VAL A C     1 
ATOM   3206  O  O     . VAL C 2 2   ? 36.270  79.632  34.036  1.00 30.79  ? 2    VAL A O     1 
ATOM   3207  C  CB    . VAL C 2 2   ? 33.293  79.951  33.827  1.00 31.64  ? 2    VAL A CB    1 
ATOM   3208  C  CG1   . VAL C 2 2   ? 33.275  79.457  35.241  1.00 20.54  ? 2    VAL A CG1   1 
ATOM   3209  C  CG2   . VAL C 2 2   ? 31.917  80.515  33.520  1.00 24.30  ? 2    VAL A CG2   1 
ATOM   3210  N  N     . VAL C 2 3   ? 36.009  81.400  35.395  1.00 27.52  ? 3    VAL A N     1 
ATOM   3211  C  CA    . VAL C 2 3   ? 37.171  81.086  36.229  1.00 30.30  ? 3    VAL A CA    1 
ATOM   3212  C  C     . VAL C 2 3   ? 36.747  81.021  37.703  1.00 27.83  ? 3    VAL A C     1 
ATOM   3213  O  O     . VAL C 2 3   ? 36.191  81.988  38.239  1.00 28.12  ? 3    VAL A O     1 
ATOM   3214  C  CB    . VAL C 2 3   ? 38.286  82.159  36.089  1.00 23.23  ? 3    VAL A CB    1 
ATOM   3215  C  CG1   . VAL C 2 3   ? 39.458  81.837  37.011  1.00 18.57  ? 3    VAL A CG1   1 
ATOM   3216  C  CG2   . VAL C 2 3   ? 38.764  82.208  34.670  1.00 25.46  ? 3    VAL A CG2   1 
ATOM   3217  N  N     . THR C 2 4   ? 36.997  79.887  38.343  1.00 21.52  ? 4    THR A N     1 
ATOM   3218  C  CA    . THR C 2 4   ? 36.669  79.731  39.765  1.00 27.73  ? 4    THR A CA    1 
ATOM   3219  C  C     . THR C 2 4   ? 37.947  79.449  40.584  1.00 29.71  ? 4    THR A C     1 
ATOM   3220  O  O     . THR C 2 4   ? 39.024  79.247  40.025  1.00 34.74  ? 4    THR A O     1 
ATOM   3221  C  CB    . THR C 2 4   ? 35.723  78.538  40.000  1.00 29.65  ? 4    THR A CB    1 
ATOM   3222  O  OG1   . THR C 2 4   ? 36.383  77.322  39.635  1.00 21.66  ? 4    THR A OG1   1 
ATOM   3223  C  CG2   . THR C 2 4   ? 34.466  78.685  39.192  1.00 33.23  ? 4    THR A CG2   1 
ATOM   3224  N  N     . ARG C 2 5   ? 37.835  79.442  41.905  1.00 28.05  ? 5    ARG A N     1 
ATOM   3225  C  CA    . ARG C 2 5   ? 38.990  79.123  42.735  1.00 26.28  ? 5    ARG A CA    1 
ATOM   3226  C  C     . ARG C 2 5   ? 38.655  78.672  44.129  1.00 25.36  ? 5    ARG A C     1 
ATOM   3227  O  O     . ARG C 2 5   ? 37.557  78.906  44.613  1.00 32.57  ? 5    ARG A O     1 
ATOM   3228  C  CB    . ARG C 2 5   ? 39.956  80.304  42.853  1.00 27.69  ? 5    ARG A CB    1 
ATOM   3229  C  CG    . ARG C 2 5   ? 39.386  81.685  43.196  1.00 25.89  ? 5    ARG A CG    1 
ATOM   3230  C  CD    . ARG C 2 5   ? 38.213  81.723  44.131  1.00 33.74  ? 5    ARG A CD    1 
ATOM   3231  N  NE    . ARG C 2 5   ? 38.017  83.040  44.748  1.00 23.98  ? 5    ARG A NE    1 
ATOM   3232  C  CZ    . ARG C 2 5   ? 37.391  83.175  45.915  1.00 32.89  ? 5    ARG A CZ    1 
ATOM   3233  N  NH1   . ARG C 2 5   ? 36.931  82.083  46.497  1.00 26.38  ? 5    ARG A NH1   1 
ATOM   3234  N  NH2   . ARG C 2 5   ? 37.274  84.351  46.531  1.00 21.09  ? 5    ARG A NH2   1 
ATOM   3235  N  N     . ILE C 2 6   ? 39.612  77.984  44.748  1.00 27.68  ? 6    ILE A N     1 
ATOM   3236  C  CA    . ILE C 2 6   ? 39.512  77.555  46.133  1.00 25.76  ? 6    ILE A CA    1 
ATOM   3237  C  C     . ILE C 2 6   ? 40.681  78.363  46.734  1.00 32.20  ? 6    ILE A C     1 
ATOM   3238  O  O     . ILE C 2 6   ? 41.729  78.525  46.098  1.00 32.93  ? 6    ILE A O     1 
ATOM   3239  C  CB    . ILE C 2 6   ? 39.697  76.006  46.304  1.00 23.25  ? 6    ILE A CB    1 
ATOM   3240  C  CG1   . ILE C 2 6   ? 39.505  75.622  47.764  1.00 29.80  ? 6    ILE A CG1   1 
ATOM   3241  C  CG2   . ILE C 2 6   ? 41.073  75.560  45.918  1.00 23.25  ? 6    ILE A CG2   1 
ATOM   3242  C  CD1   . ILE C 2 6   ? 38.184  76.047  48.351  1.00 27.15  ? 6    ILE A CD1   1 
ATOM   3243  N  N     . ALA C 2 7   ? 40.505  78.919  47.921  1.00 23.87  ? 7    ALA A N     1 
ATOM   3244  C  CA    . ALA C 2 7   ? 41.571  79.726  48.475  1.00 20.58  ? 7    ALA A CA    1 
ATOM   3245  C  C     . ALA C 2 7   ? 41.820  79.405  49.949  1.00 29.88  ? 7    ALA A C     1 
ATOM   3246  O  O     . ALA C 2 7   ? 41.583  80.228  50.841  1.00 19.24  ? 7    ALA A O     1 
ATOM   3247  C  CB    . ALA C 2 7   ? 41.247  81.213  48.296  1.00 22.86  ? 7    ALA A CB    1 
ATOM   3248  N  N     . PRO C 2 8   ? 42.331  78.196  50.211  1.00 26.37  ? 8    PRO A N     1 
ATOM   3249  C  CA    . PRO C 2 8   ? 42.638  77.700  51.555  1.00 27.76  ? 8    PRO A CA    1 
ATOM   3250  C  C     . PRO C 2 8   ? 43.653  78.562  52.285  1.00 27.80  ? 8    PRO A C     1 
ATOM   3251  O  O     . PRO C 2 8   ? 44.543  79.170  51.671  1.00 22.96  ? 8    PRO A O     1 
ATOM   3252  C  CB    . PRO C 2 8   ? 43.204  76.299  51.319  1.00 25.91  ? 8    PRO A CB    1 
ATOM   3253  C  CG    . PRO C 2 8   ? 43.180  76.096  49.826  1.00 26.71  ? 8    PRO A CG    1 
ATOM   3254  C  CD    . PRO C 2 8   ? 43.011  77.412  49.175  1.00 24.49  ? 8    PRO A CD    1 
ATOM   3255  N  N     . SER C 2 9   ? 43.493  78.612  53.603  1.00 28.04  ? 9    SER A N     1 
ATOM   3256  C  CA    . SER C 2 9   ? 44.394  79.345  54.485  1.00 27.40  ? 9    SER A CA    1 
ATOM   3257  C  C     . SER C 2 9   ? 45.198  78.222  55.126  1.00 27.20  ? 9    SER A C     1 
ATOM   3258  O  O     . SER C 2 9   ? 44.628  77.282  55.652  1.00 25.00  ? 9    SER A O     1 
ATOM   3259  C  CB    . SER C 2 9   ? 43.595  80.100  55.537  1.00 26.63  ? 9    SER A CB    1 
ATOM   3260  O  OG    . SER C 2 9   ? 44.333  81.176  56.060  1.00 51.50  ? 9    SER A OG    1 
ATOM   3261  N  N     . PRO C 2 10  ? 46.538  78.282  55.067  1.00 33.51  ? 10   PRO A N     1 
ATOM   3262  C  CA    . PRO C 2 10  ? 47.365  77.220  55.661  1.00 31.03  ? 10   PRO A CA    1 
ATOM   3263  C  C     . PRO C 2 10  ? 47.508  77.415  57.174  1.00 27.71  ? 10   PRO A C     1 
ATOM   3264  O  O     . PRO C 2 10  ? 48.568  77.760  57.646  1.00 31.19  ? 10   PRO A O     1 
ATOM   3265  C  CB    . PRO C 2 10  ? 48.683  77.402  54.940  1.00 23.29  ? 10   PRO A CB    1 
ATOM   3266  C  CG    . PRO C 2 10  ? 48.798  78.872  54.919  1.00 28.69  ? 10   PRO A CG    1 
ATOM   3267  C  CD    . PRO C 2 10  ? 47.389  79.359  54.545  1.00 24.50  ? 10   PRO A CD    1 
ATOM   3268  N  N     . THR C 2 11  ? 46.452  77.156  57.928  1.00 24.59  ? 11   THR A N     1 
ATOM   3269  C  CA    . THR C 2 11  ? 46.499  77.384  59.363  1.00 31.25  ? 11   THR A CA    1 
ATOM   3270  C  C     . THR C 2 11  ? 45.971  76.239  60.210  1.00 28.35  ? 11   THR A C     1 
ATOM   3271  O  O     . THR C 2 11  ? 45.487  76.453  61.303  1.00 35.96  ? 11   THR A O     1 
ATOM   3272  C  CB    . THR C 2 11  ? 45.723  78.672  59.696  1.00 32.14  ? 11   THR A CB    1 
ATOM   3273  O  OG1   . THR C 2 11  ? 44.418  78.578  59.121  1.00 30.83  ? 11   THR A OG1   1 
ATOM   3274  C  CG2   . THR C 2 11  ? 46.425  79.909  59.091  1.00 25.11  ? 11   THR A CG2   1 
ATOM   3275  N  N     . GLY C 2 12  ? 46.091  75.021  59.707  1.00 29.57  ? 12   GLY A N     1 
ATOM   3276  C  CA    . GLY C 2 12  ? 45.618  73.853  60.428  1.00 22.13  ? 12   GLY A CA    1 
ATOM   3277  C  C     . GLY C 2 12  ? 45.605  72.680  59.459  1.00 30.48  ? 12   GLY A C     1 
ATOM   3278  O  O     . GLY C 2 12  ? 46.161  72.777  58.353  1.00 35.90  ? 12   GLY A O     1 
ATOM   3279  N  N     . ASP C 2 13  ? 44.971  71.582  59.852  1.00 24.28  ? 13   ASP A N     1 
ATOM   3280  C  CA    . ASP C 2 13  ? 44.906  70.419  58.998  1.00 30.78  ? 13   ASP A CA    1 
ATOM   3281  C  C     . ASP C 2 13  ? 44.034  70.654  57.763  1.00 32.54  ? 13   ASP A C     1 
ATOM   3282  O  O     . ASP C 2 13  ? 43.241  71.601  57.721  1.00 32.62  ? 13   ASP A O     1 
ATOM   3283  C  CB    . ASP C 2 13  ? 44.325  69.247  59.789  1.00 42.39  ? 13   ASP A CB    1 
ATOM   3284  C  CG    . ASP C 2 13  ? 45.189  68.840  60.962  1.00 40.05  ? 13   ASP A CG    1 
ATOM   3285  O  OD1   . ASP C 2 13  ? 46.394  69.172  60.970  1.00 42.83  ? 13   ASP A OD1   1 
ATOM   3286  O  OD2   . ASP C 2 13  ? 44.659  68.163  61.865  1.00 47.65  ? 13   ASP A OD2   1 
ATOM   3287  N  N     . PRO C 2 14  ? 44.186  69.808  56.729  1.00 30.90  ? 14   PRO A N     1 
ATOM   3288  C  CA    . PRO C 2 14  ? 43.380  69.931  55.505  1.00 30.80  ? 14   PRO A CA    1 
ATOM   3289  C  C     . PRO C 2 14  ? 41.942  69.699  55.987  1.00 28.16  ? 14   PRO A C     1 
ATOM   3290  O  O     . PRO C 2 14  ? 41.632  68.646  56.533  1.00 28.62  ? 14   PRO A O     1 
ATOM   3291  C  CB    . PRO C 2 14  ? 43.895  68.792  54.640  1.00 32.50  ? 14   PRO A CB    1 
ATOM   3292  C  CG    . PRO C 2 14  ? 45.332  68.633  55.093  1.00 33.79  ? 14   PRO A CG    1 
ATOM   3293  C  CD    . PRO C 2 14  ? 45.190  68.743  56.593  1.00 35.82  ? 14   PRO A CD    1 
ATOM   3294  N  N     . HIS C 2 15  ? 41.099  70.698  55.777  1.00 24.33  ? 15   HIS A N     1 
ATOM   3295  C  CA    . HIS C 2 15  ? 39.720  70.738  56.255  1.00 25.27  ? 15   HIS A CA    1 
ATOM   3296  C  C     . HIS C 2 15  ? 38.667  70.274  55.279  1.00 25.46  ? 15   HIS A C     1 
ATOM   3297  O  O     . HIS C 2 15  ? 38.643  70.710  54.132  1.00 34.18  ? 15   HIS A O     1 
ATOM   3298  C  CB    . HIS C 2 15  ? 39.422  72.186  56.663  1.00 36.49  ? 15   HIS A CB    1 
ATOM   3299  C  CG    . HIS C 2 15  ? 38.250  72.344  57.579  1.00 46.94  ? 15   HIS A CG    1 
ATOM   3300  N  ND1   . HIS C 2 15  ? 36.951  72.096  57.184  1.00 48.37  ? 15   HIS A ND1   1 
ATOM   3301  C  CD2   . HIS C 2 15  ? 38.182  72.736  58.874  1.00 36.12  ? 15   HIS A CD2   1 
ATOM   3302  C  CE1   . HIS C 2 15  ? 36.134  72.328  58.199  1.00 42.89  ? 15   HIS A CE1   1 
ATOM   3303  N  NE2   . HIS C 2 15  ? 36.857  72.716  59.234  1.00 38.59  ? 15   HIS A NE2   1 
ATOM   3304  N  N     . VAL C 2 16  ? 37.767  69.426  55.758  1.00 22.56  ? 16   VAL A N     1 
ATOM   3305  C  CA    . VAL C 2 16  ? 36.698  68.893  54.933  1.00 29.46  ? 16   VAL A CA    1 
ATOM   3306  C  C     . VAL C 2 16  ? 35.839  69.996  54.331  1.00 24.96  ? 16   VAL A C     1 
ATOM   3307  O  O     . VAL C 2 16  ? 35.292  69.842  53.249  1.00 24.48  ? 16   VAL A O     1 
ATOM   3308  C  CB    . VAL C 2 16  ? 35.815  67.884  55.742  1.00 37.16  ? 16   VAL A CB    1 
ATOM   3309  C  CG1   . VAL C 2 16  ? 35.207  68.552  56.967  1.00 40.17  ? 16   VAL A CG1   1 
ATOM   3310  C  CG2   . VAL C 2 16  ? 34.737  67.311  54.840  1.00 37.43  ? 16   VAL A CG2   1 
ATOM   3311  N  N     . GLY C 2 17  ? 35.737  71.117  55.038  1.00 29.85  ? 17   GLY A N     1 
ATOM   3312  C  CA    . GLY C 2 17  ? 34.959  72.237  54.535  1.00 26.69  ? 17   GLY A CA    1 
ATOM   3313  C  C     . GLY C 2 17  ? 35.608  72.753  53.266  1.00 26.76  ? 17   GLY A C     1 
ATOM   3314  O  O     . GLY C 2 17  ? 34.943  73.219  52.341  1.00 29.83  ? 17   GLY A O     1 
ATOM   3315  N  N     . THR C 2 18  ? 36.927  72.639  53.215  1.00 23.74  ? 18   THR A N     1 
ATOM   3316  C  CA    . THR C 2 18  ? 37.685  73.072  52.052  1.00 22.86  ? 18   THR A CA    1 
ATOM   3317  C  C     . THR C 2 18  ? 37.418  72.129  50.883  1.00 22.59  ? 18   THR A C     1 
ATOM   3318  O  O     . THR C 2 18  ? 37.193  72.582  49.777  1.00 17.68  ? 18   THR A O     1 
ATOM   3319  C  CB    . THR C 2 18  ? 39.192  73.064  52.346  1.00 26.54  ? 18   THR A CB    1 
ATOM   3320  O  OG1   . THR C 2 18  ? 39.450  74.028  53.354  1.00 24.79  ? 18   THR A OG1   1 
ATOM   3321  C  CG2   . THR C 2 18  ? 40.021  73.403  51.079  1.00 25.49  ? 18   THR A CG2   1 
ATOM   3322  N  N     . ALA C 2 19  ? 37.452  70.824  51.128  1.00 16.34  ? 19   ALA A N     1 
ATOM   3323  C  CA    . ALA C 2 19  ? 37.213  69.883  50.037  1.00 25.32  ? 19   ALA A CA    1 
ATOM   3324  C  C     . ALA C 2 19  ? 35.843  70.115  49.468  1.00 29.84  ? 19   ALA A C     1 
ATOM   3325  O  O     . ALA C 2 19  ? 35.647  70.110  48.250  1.00 29.42  ? 19   ALA A O     1 
ATOM   3326  C  CB    . ALA C 2 19  ? 37.300  68.469  50.518  1.00 15.55  ? 19   ALA A CB    1 
ATOM   3327  N  N     . TYR C 2 20  ? 34.896  70.307  50.380  1.00 28.17  ? 20   TYR A N     1 
ATOM   3328  C  CA    . TYR C 2 20  ? 33.507  70.506  50.023  1.00 24.08  ? 20   TYR A CA    1 
ATOM   3329  C  C     . TYR C 2 20  ? 33.355  71.683  49.069  1.00 27.52  ? 20   TYR A C     1 
ATOM   3330  O  O     . TYR C 2 20  ? 32.775  71.550  47.988  1.00 29.72  ? 20   TYR A O     1 
ATOM   3331  C  CB    . TYR C 2 20  ? 32.696  70.707  51.308  1.00 28.16  ? 20   TYR A CB    1 
ATOM   3332  C  CG    . TYR C 2 20  ? 31.308  71.244  51.127  1.00 17.78  ? 20   TYR A CG    1 
ATOM   3333  C  CD1   . TYR C 2 20  ? 30.340  70.535  50.406  1.00 22.52  ? 20   TYR A CD1   1 
ATOM   3334  C  CD2   . TYR C 2 20  ? 30.947  72.456  51.706  1.00 31.30  ? 20   TYR A CD2   1 
ATOM   3335  C  CE1   . TYR C 2 20  ? 29.032  71.023  50.272  1.00 18.58  ? 20   TYR A CE1   1 
ATOM   3336  C  CE2   . TYR C 2 20  ? 29.654  72.958  51.582  1.00 29.08  ? 20   TYR A CE2   1 
ATOM   3337  C  CZ    . TYR C 2 20  ? 28.701  72.244  50.870  1.00 31.10  ? 20   TYR A CZ    1 
ATOM   3338  O  OH    . TYR C 2 20  ? 27.422  72.766  50.777  1.00 41.33  ? 20   TYR A OH    1 
ATOM   3339  N  N     . ILE C 2 21  ? 33.889  72.834  49.456  1.00 24.72  ? 21   ILE A N     1 
ATOM   3340  C  CA    . ILE C 2 21  ? 33.779  74.009  48.612  1.00 20.77  ? 21   ILE A CA    1 
ATOM   3341  C  C     . ILE C 2 21  ? 34.619  73.842  47.322  1.00 27.77  ? 21   ILE A C     1 
ATOM   3342  O  O     . ILE C 2 21  ? 34.232  74.300  46.250  1.00 23.02  ? 21   ILE A O     1 
ATOM   3343  C  CB    . ILE C 2 21  ? 34.242  75.262  49.397  1.00 16.65  ? 21   ILE A CB    1 
ATOM   3344  C  CG1   . ILE C 2 21  ? 33.250  75.561  50.532  1.00 29.18  ? 21   ILE A CG1   1 
ATOM   3345  C  CG2   . ILE C 2 21  ? 34.345  76.481  48.469  1.00 15.04  ? 21   ILE A CG2   1 
ATOM   3346  C  CD1   . ILE C 2 21  ? 31.842  75.913  50.050  1.00 22.65  ? 21   ILE A CD1   1 
ATOM   3347  N  N     . ALA C 2 22  ? 35.766  73.188  47.429  1.00 17.99  ? 22   ALA A N     1 
ATOM   3348  C  CA    . ALA C 2 22  ? 36.636  72.997  46.280  1.00 26.40  ? 22   ALA A CA    1 
ATOM   3349  C  C     . ALA C 2 22  ? 35.905  72.145  45.231  1.00 28.52  ? 22   ALA A C     1 
ATOM   3350  O  O     . ALA C 2 22  ? 36.003  72.380  44.020  1.00 34.23  ? 22   ALA A O     1 
ATOM   3351  C  CB    . ALA C 2 22  ? 37.958  72.303  46.720  1.00 20.15  ? 22   ALA A CB    1 
ATOM   3352  N  N     . LEU C 2 23  ? 35.163  71.162  45.712  1.00 26.88  ? 23   LEU A N     1 
ATOM   3353  C  CA    . LEU C 2 23  ? 34.406  70.274  44.852  1.00 27.95  ? 23   LEU A CA    1 
ATOM   3354  C  C     . LEU C 2 23  ? 33.397  71.023  43.964  1.00 30.09  ? 23   LEU A C     1 
ATOM   3355  O  O     . LEU C 2 23  ? 33.274  70.732  42.773  1.00 27.19  ? 23   LEU A O     1 
ATOM   3356  C  CB    . LEU C 2 23  ? 33.689  69.253  45.729  1.00 28.80  ? 23   LEU A CB    1 
ATOM   3357  C  CG    . LEU C 2 23  ? 32.831  68.168  45.108  1.00 30.86  ? 23   LEU A CG    1 
ATOM   3358  C  CD1   . LEU C 2 23  ? 33.640  67.417  44.084  1.00 38.07  ? 23   LEU A CD1   1 
ATOM   3359  C  CD2   . LEU C 2 23  ? 32.373  67.215  46.188  1.00 40.45  ? 23   LEU A CD2   1 
ATOM   3360  N  N     . PHE C 2 24  ? 32.684  71.995  44.523  1.00 26.40  ? 24   PHE A N     1 
ATOM   3361  C  CA    . PHE C 2 24  ? 31.696  72.712  43.727  1.00 26.15  ? 24   PHE A CA    1 
ATOM   3362  C  C     . PHE C 2 24  ? 32.331  73.712  42.763  1.00 30.29  ? 24   PHE A C     1 
ATOM   3363  O  O     . PHE C 2 24  ? 31.809  73.975  41.678  1.00 25.15  ? 24   PHE A O     1 
ATOM   3364  C  CB    . PHE C 2 24  ? 30.647  73.368  44.641  1.00 27.22  ? 24   PHE A CB    1 
ATOM   3365  C  CG    . PHE C 2 24  ? 29.653  72.382  45.207  1.00 21.79  ? 24   PHE A CG    1 
ATOM   3366  C  CD1   . PHE C 2 24  ? 29.999  71.547  46.271  1.00 20.02  ? 24   PHE A CD1   1 
ATOM   3367  C  CD2   . PHE C 2 24  ? 28.401  72.202  44.606  1.00 27.91  ? 24   PHE A CD2   1 
ATOM   3368  C  CE1   . PHE C 2 24  ? 29.112  70.529  46.723  1.00 29.28  ? 24   PHE A CE1   1 
ATOM   3369  C  CE2   . PHE C 2 24  ? 27.512  71.185  45.054  1.00 26.22  ? 24   PHE A CE2   1 
ATOM   3370  C  CZ    . PHE C 2 24  ? 27.872  70.349  46.109  1.00 17.30  ? 24   PHE A CZ    1 
ATOM   3371  N  N     . ASN C 2 25  ? 33.482  74.240  43.145  1.00 26.14  ? 25   ASN A N     1 
ATOM   3372  C  CA    . ASN C 2 25  ? 34.210  75.166  42.290  1.00 27.07  ? 25   ASN A CA    1 
ATOM   3373  C  C     . ASN C 2 25  ? 34.765  74.436  41.086  1.00 26.01  ? 25   ASN A C     1 
ATOM   3374  O  O     . ASN C 2 25  ? 34.701  74.906  39.952  1.00 23.11  ? 25   ASN A O     1 
ATOM   3375  C  CB    . ASN C 2 25  ? 35.354  75.782  43.067  1.00 21.65  ? 25   ASN A CB    1 
ATOM   3376  C  CG    . ASN C 2 25  ? 34.931  77.019  43.774  1.00 23.28  ? 25   ASN A CG    1 
ATOM   3377  O  OD1   . ASN C 2 25  ? 34.847  78.085  43.158  1.00 26.41  ? 25   ASN A OD1   1 
ATOM   3378  N  ND2   . ASN C 2 25  ? 34.610  76.894  45.062  1.00 13.57  ? 25   ASN A ND2   1 
ATOM   3379  N  N     . TYR C 2 26  ? 35.323  73.271  41.362  1.00 25.53  ? 26   TYR A N     1 
ATOM   3380  C  CA    . TYR C 2 26  ? 35.882  72.457  40.319  1.00 27.09  ? 26   TYR A CA    1 
ATOM   3381  C  C     . TYR C 2 26  ? 34.779  72.040  39.330  1.00 26.73  ? 26   TYR A C     1 
ATOM   3382  O  O     . TYR C 2 26  ? 34.944  72.133  38.117  1.00 23.02  ? 26   TYR A O     1 
ATOM   3383  C  CB    . TYR C 2 26  ? 36.566  71.264  40.960  1.00 15.30  ? 26   TYR A CB    1 
ATOM   3384  C  CG    . TYR C 2 26  ? 36.880  70.137  40.024  1.00 25.25  ? 26   TYR A CG    1 
ATOM   3385  C  CD1   . TYR C 2 26  ? 35.948  69.119  39.810  1.00 26.34  ? 26   TYR A CD1   1 
ATOM   3386  C  CD2   . TYR C 2 26  ? 38.121  70.057  39.374  1.00 24.11  ? 26   TYR A CD2   1 
ATOM   3387  C  CE1   . TYR C 2 26  ? 36.234  68.047  38.983  1.00 25.02  ? 26   TYR A CE1   1 
ATOM   3388  C  CE2   . TYR C 2 26  ? 38.425  68.980  38.534  1.00 20.97  ? 26   TYR A CE2   1 
ATOM   3389  C  CZ    . TYR C 2 26  ? 37.472  67.973  38.350  1.00 28.34  ? 26   TYR A CZ    1 
ATOM   3390  O  OH    . TYR C 2 26  ? 37.733  66.862  37.578  1.00 30.61  ? 26   TYR A OH    1 
ATOM   3391  N  N     . ALA C 2 27  ? 33.637  71.615  39.846  1.00 23.75  ? 27   ALA A N     1 
ATOM   3392  C  CA    . ALA C 2 27  ? 32.571  71.198  38.955  1.00 21.56  ? 27   ALA A CA    1 
ATOM   3393  C  C     . ALA C 2 27  ? 32.039  72.346  38.128  1.00 21.96  ? 27   ALA A C     1 
ATOM   3394  O  O     . ALA C 2 27  ? 31.863  72.202  36.941  1.00 26.84  ? 27   ALA A O     1 
ATOM   3395  C  CB    . ALA C 2 27  ? 31.451  70.557  39.732  1.00 20.40  ? 27   ALA A CB    1 
ATOM   3396  N  N     . TRP C 2 28  ? 31.796  73.500  38.739  1.00 22.35  ? 28   TRP A N     1 
ATOM   3397  C  CA    . TRP C 2 28  ? 31.253  74.598  37.961  1.00 24.26  ? 28   TRP A CA    1 
ATOM   3398  C  C     . TRP C 2 28  ? 32.235  75.039  36.887  1.00 30.80  ? 28   TRP A C     1 
ATOM   3399  O  O     . TRP C 2 28  ? 31.836  75.449  35.805  1.00 32.81  ? 28   TRP A O     1 
ATOM   3400  C  CB    . TRP C 2 28  ? 30.924  75.771  38.861  1.00 19.31  ? 28   TRP A CB    1 
ATOM   3401  C  CG    . TRP C 2 28  ? 30.256  76.919  38.202  1.00 22.87  ? 28   TRP A CG    1 
ATOM   3402  C  CD1   . TRP C 2 28  ? 30.656  78.217  38.255  1.00 34.08  ? 28   TRP A CD1   1 
ATOM   3403  C  CD2   . TRP C 2 28  ? 29.019  76.910  37.477  1.00 22.40  ? 28   TRP A CD2   1 
ATOM   3404  N  NE1   . TRP C 2 28  ? 29.748  79.023  37.617  1.00 28.46  ? 28   TRP A NE1   1 
ATOM   3405  C  CE2   . TRP C 2 28  ? 28.731  78.248  37.126  1.00 27.90  ? 28   TRP A CE2   1 
ATOM   3406  C  CE3   . TRP C 2 28  ? 28.122  75.905  37.091  1.00 31.35  ? 28   TRP A CE3   1 
ATOM   3407  C  CZ2   . TRP C 2 28  ? 27.575  78.615  36.401  1.00 26.66  ? 28   TRP A CZ2   1 
ATOM   3408  C  CZ3   . TRP C 2 28  ? 26.956  76.273  36.364  1.00 30.52  ? 28   TRP A CZ3   1 
ATOM   3409  C  CH2   . TRP C 2 28  ? 26.705  77.615  36.035  1.00 30.45  ? 28   TRP A CH2   1 
ATOM   3410  N  N     . ALA C 2 29  ? 33.524  74.977  37.187  1.00 25.45  ? 29   ALA A N     1 
ATOM   3411  C  CA    . ALA C 2 29  ? 34.486  75.388  36.192  1.00 29.15  ? 29   ALA A CA    1 
ATOM   3412  C  C     . ALA C 2 29  ? 34.464  74.407  35.012  1.00 22.43  ? 29   ALA A C     1 
ATOM   3413  O  O     . ALA C 2 29  ? 34.431  74.821  33.881  1.00 23.57  ? 29   ALA A O     1 
ATOM   3414  C  CB    . ALA C 2 29  ? 35.883  75.453  36.802  1.00 26.62  ? 29   ALA A CB    1 
ATOM   3415  N  N     . ARG C 2 30  ? 34.465  73.111  35.275  1.00 20.88  ? 30   ARG A N     1 
ATOM   3416  C  CA    . ARG C 2 30  ? 34.495  72.154  34.179  1.00 28.15  ? 30   ARG A CA    1 
ATOM   3417  C  C     . ARG C 2 30  ? 33.194  72.133  33.422  1.00 35.79  ? 30   ARG A C     1 
ATOM   3418  O  O     . ARG C 2 30  ? 33.183  72.149  32.192  1.00 36.58  ? 30   ARG A O     1 
ATOM   3419  C  CB    . ARG C 2 30  ? 34.833  70.776  34.702  1.00 25.02  ? 30   ARG A CB    1 
ATOM   3420  C  CG    . ARG C 2 30  ? 36.272  70.702  35.167  1.00 27.80  ? 30   ARG A CG    1 
ATOM   3421  C  CD    . ARG C 2 30  ? 37.241  70.385  34.004  1.00 24.41  ? 30   ARG A CD    1 
ATOM   3422  N  NE    . ARG C 2 30  ? 38.589  70.163  34.520  1.00 25.73  ? 30   ARG A NE    1 
ATOM   3423  C  CZ    . ARG C 2 30  ? 39.467  71.140  34.737  1.00 28.04  ? 30   ARG A CZ    1 
ATOM   3424  N  NH1   . ARG C 2 30  ? 39.144  72.399  34.466  1.00 26.56  ? 30   ARG A NH1   1 
ATOM   3425  N  NH2   . ARG C 2 30  ? 40.654  70.866  35.262  1.00 28.67  ? 30   ARG A NH2   1 
ATOM   3426  N  N     . ARG C 2 31  ? 32.091  72.111  34.154  1.00 31.33  ? 31   ARG A N     1 
ATOM   3427  C  CA    . ARG C 2 31  ? 30.791  72.125  33.520  1.00 32.27  ? 31   ARG A CA    1 
ATOM   3428  C  C     . ARG C 2 31  ? 30.741  73.229  32.450  1.00 34.44  ? 31   ARG A C     1 
ATOM   3429  O  O     . ARG C 2 31  ? 30.043  73.083  31.465  1.00 37.63  ? 31   ARG A O     1 
ATOM   3430  C  CB    . ARG C 2 31  ? 29.711  72.388  34.560  1.00 33.38  ? 31   ARG A CB    1 
ATOM   3431  C  CG    . ARG C 2 31  ? 28.330  72.531  33.978  1.00 32.55  ? 31   ARG A CG    1 
ATOM   3432  C  CD    . ARG C 2 31  ? 27.719  71.174  33.694  1.00 42.76  ? 31   ARG A CD    1 
ATOM   3433  N  NE    . ARG C 2 31  ? 26.409  71.324  33.080  1.00 55.68  ? 31   ARG A NE    1 
ATOM   3434  C  CZ    . ARG C 2 31  ? 26.234  71.696  31.817  1.00 66.37  ? 31   ARG A CZ    1 
ATOM   3435  N  NH1   . ARG C 2 31  ? 27.296  71.936  31.042  1.00 49.14  ? 31   ARG A NH1   1 
ATOM   3436  N  NH2   . ARG C 2 31  ? 25.002  71.864  31.342  1.00 64.72  ? 31   ARG A NH2   1 
ATOM   3437  N  N     . ASN C 2 32  ? 31.499  74.312  32.649  1.00 37.15  ? 32   ASN A N     1 
ATOM   3438  C  CA    . ASN C 2 32  ? 31.527  75.458  31.736  1.00 32.17  ? 32   ASN A CA    1 
ATOM   3439  C  C     . ASN C 2 32  ? 32.788  75.547  30.881  1.00 33.80  ? 32   ASN A C     1 
ATOM   3440  O  O     . ASN C 2 32  ? 33.027  76.564  30.212  1.00 29.63  ? 32   ASN A O     1 
ATOM   3441  C  CB    . ASN C 2 32  ? 31.396  76.754  32.542  1.00 33.02  ? 32   ASN A CB    1 
ATOM   3442  C  CG    . ASN C 2 32  ? 29.992  76.969  33.091  1.00 40.41  ? 32   ASN A CG    1 
ATOM   3443  O  OD1   . ASN C 2 32  ? 29.153  77.549  32.418  1.00 47.67  ? 32   ASN A OD1   1 
ATOM   3444  N  ND2   . ASN C 2 32  ? 29.726  76.489  34.306  1.00 29.83  ? 32   ASN A ND2   1 
ATOM   3445  N  N     . GLY C 2 33  ? 33.595  74.491  30.898  1.00 32.91  ? 33   GLY A N     1 
ATOM   3446  C  CA    . GLY C 2 33  ? 34.844  74.514  30.144  1.00 32.33  ? 33   GLY A CA    1 
ATOM   3447  C  C     . GLY C 2 33  ? 35.699  75.698  30.574  1.00 29.62  ? 33   GLY A C     1 
ATOM   3448  O  O     . GLY C 2 33  ? 36.365  76.340  29.769  1.00 36.06  ? 33   GLY A O     1 
ATOM   3449  N  N     . GLY C 2 34  ? 35.666  76.004  31.860  1.00 30.19  ? 34   GLY A N     1 
ATOM   3450  C  CA    . GLY C 2 34  ? 36.435  77.121  32.383  1.00 30.97  ? 34   GLY A CA    1 
ATOM   3451  C  C     . GLY C 2 34  ? 37.686  76.685  33.134  1.00 26.13  ? 34   GLY A C     1 
ATOM   3452  O  O     . GLY C 2 34  ? 38.176  75.577  32.968  1.00 27.97  ? 34   GLY A O     1 
ATOM   3453  N  N     . ARG C 2 35  ? 38.184  77.565  33.986  1.00 30.92  ? 35   ARG A N     1 
ATOM   3454  C  CA    . ARG C 2 35  ? 39.402  77.308  34.745  1.00 32.81  ? 35   ARG A CA    1 
ATOM   3455  C  C     . ARG C 2 35  ? 39.172  77.325  36.258  1.00 19.17  ? 35   ARG A C     1 
ATOM   3456  O  O     . ARG C 2 35  ? 38.420  78.146  36.766  1.00 34.67  ? 35   ARG A O     1 
ATOM   3457  C  CB    . ARG C 2 35  ? 40.441  78.347  34.331  1.00 25.11  ? 35   ARG A CB    1 
ATOM   3458  C  CG    . ARG C 2 35  ? 41.660  77.751  33.703  1.00 51.03  ? 35   ARG A CG    1 
ATOM   3459  C  CD    . ARG C 2 35  ? 42.412  78.735  32.810  1.00 40.41  ? 35   ARG A CD    1 
ATOM   3460  N  NE    . ARG C 2 35  ? 42.410  80.077  33.358  1.00 45.40  ? 35   ARG A NE    1 
ATOM   3461  C  CZ    . ARG C 2 35  ? 41.904  81.130  32.720  1.00 56.72  ? 35   ARG A CZ    1 
ATOM   3462  N  NH1   . ARG C 2 35  ? 41.370  80.968  31.510  1.00 47.59  ? 35   ARG A NH1   1 
ATOM   3463  N  NH2   . ARG C 2 35  ? 41.919  82.336  33.293  1.00 47.16  ? 35   ARG A NH2   1 
ATOM   3464  N  N     . PHE C 2 36  ? 39.828  76.399  36.953  1.00 24.84  ? 36   PHE A N     1 
ATOM   3465  C  CA    . PHE C 2 36  ? 39.756  76.227  38.405  1.00 17.65  ? 36   PHE A CA    1 
ATOM   3466  C  C     . PHE C 2 36  ? 41.162  76.425  39.027  1.00 21.17  ? 36   PHE A C     1 
ATOM   3467  O  O     . PHE C 2 36  ? 42.072  75.594  38.865  1.00 16.94  ? 36   PHE A O     1 
ATOM   3468  C  CB    . PHE C 2 36  ? 39.230  74.813  38.726  1.00 16.55  ? 36   PHE A CB    1 
ATOM   3469  C  CG    . PHE C 2 36  ? 39.309  74.448  40.187  1.00 19.79  ? 36   PHE A CG    1 
ATOM   3470  C  CD1   . PHE C 2 36  ? 39.816  73.213  40.578  1.00 26.40  ? 36   PHE A CD1   1 
ATOM   3471  C  CD2   . PHE C 2 36  ? 38.889  75.342  41.172  1.00 24.39  ? 36   PHE A CD2   1 
ATOM   3472  C  CE1   . PHE C 2 36  ? 39.909  72.872  41.929  1.00 26.48  ? 36   PHE A CE1   1 
ATOM   3473  C  CE2   . PHE C 2 36  ? 38.970  75.015  42.533  1.00 23.64  ? 36   PHE A CE2   1 
ATOM   3474  C  CZ    . PHE C 2 36  ? 39.482  73.782  42.919  1.00 25.43  ? 36   PHE A CZ    1 
ATOM   3475  N  N     . ILE C 2 37  ? 41.287  77.519  39.766  1.00 20.92  ? 37   ILE A N     1 
ATOM   3476  C  CA    . ILE C 2 37  ? 42.511  77.992  40.446  1.00 23.86  ? 37   ILE A CA    1 
ATOM   3477  C  C     . ILE C 2 37  ? 42.631  77.671  41.947  1.00 24.77  ? 37   ILE A C     1 
ATOM   3478  O  O     . ILE C 2 37  ? 41.634  77.683  42.689  1.00 21.50  ? 37   ILE A O     1 
ATOM   3479  C  CB    . ILE C 2 37  ? 42.589  79.578  40.424  1.00 29.29  ? 37   ILE A CB    1 
ATOM   3480  C  CG1   . ILE C 2 37  ? 42.400  80.139  39.020  1.00 40.61  ? 37   ILE A CG1   1 
ATOM   3481  C  CG2   . ILE C 2 37  ? 43.890  80.047  41.006  1.00 37.81  ? 37   ILE A CG2   1 
ATOM   3482  C  CD1   . ILE C 2 37  ? 42.932  79.243  37.921  1.00 43.12  ? 37   ILE A CD1   1 
ATOM   3483  N  N     . VAL C 2 38  ? 43.866  77.451  42.400  1.00 26.02  ? 38   VAL A N     1 
ATOM   3484  C  CA    . VAL C 2 38  ? 44.138  77.272  43.823  1.00 15.79  ? 38   VAL A CA    1 
ATOM   3485  C  C     . VAL C 2 38  ? 45.009  78.482  44.195  1.00 23.14  ? 38   VAL A C     1 
ATOM   3486  O  O     . VAL C 2 38  ? 46.016  78.746  43.541  1.00 29.04  ? 38   VAL A O     1 
ATOM   3487  C  CB    . VAL C 2 38  ? 44.927  75.975  44.148  1.00 22.08  ? 38   VAL A CB    1 
ATOM   3488  C  CG1   . VAL C 2 38  ? 45.293  75.962  45.612  1.00 21.31  ? 38   VAL A CG1   1 
ATOM   3489  C  CG2   . VAL C 2 38  ? 44.102  74.740  43.848  1.00 17.06  ? 38   VAL A CG2   1 
ATOM   3490  N  N     . ARG C 2 39  ? 44.611  79.244  45.214  1.00 30.53  ? 39   ARG A N     1 
ATOM   3491  C  CA    . ARG C 2 39  ? 45.403  80.393  45.674  1.00 22.52  ? 39   ARG A CA    1 
ATOM   3492  C  C     . ARG C 2 39  ? 45.618  80.212  47.156  1.00 23.36  ? 39   ARG A C     1 
ATOM   3493  O  O     . ARG C 2 39  ? 44.657  80.106  47.897  1.00 28.52  ? 39   ARG A O     1 
ATOM   3494  C  CB    . ARG C 2 39  ? 44.673  81.719  45.442  1.00 25.84  ? 39   ARG A CB    1 
ATOM   3495  C  CG    . ARG C 2 39  ? 45.456  82.942  45.963  1.00 22.29  ? 39   ARG A CG    1 
ATOM   3496  C  CD    . ARG C 2 39  ? 44.803  84.265  45.575  1.00 23.48  ? 39   ARG A CD    1 
ATOM   3497  N  NE    . ARG C 2 39  ? 43.458  84.439  46.140  1.00 20.31  ? 39   ARG A NE    1 
ATOM   3498  C  CZ    . ARG C 2 39  ? 42.370  84.742  45.430  1.00 26.70  ? 39   ARG A CZ    1 
ATOM   3499  N  NH1   . ARG C 2 39  ? 42.449  84.904  44.119  1.00 24.35  ? 39   ARG A NH1   1 
ATOM   3500  N  NH2   . ARG C 2 39  ? 41.190  84.889  46.033  1.00 30.71  ? 39   ARG A NH2   1 
ATOM   3501  N  N     . ILE C 2 40  ? 46.868  80.139  47.601  1.00 21.51  ? 40   ILE A N     1 
ATOM   3502  C  CA    . ILE C 2 40  ? 47.130  79.948  49.018  1.00 18.25  ? 40   ILE A CA    1 
ATOM   3503  C  C     . ILE C 2 40  ? 47.045  81.278  49.721  1.00 25.50  ? 40   ILE A C     1 
ATOM   3504  O  O     . ILE C 2 40  ? 47.781  82.228  49.421  1.00 31.39  ? 40   ILE A O     1 
ATOM   3505  C  CB    . ILE C 2 40  ? 48.491  79.305  49.273  1.00 21.65  ? 40   ILE A CB    1 
ATOM   3506  C  CG1   . ILE C 2 40  ? 48.485  77.880  48.723  1.00 20.80  ? 40   ILE A CG1   1 
ATOM   3507  C  CG2   . ILE C 2 40  ? 48.763  79.270  50.770  1.00 19.09  ? 40   ILE A CG2   1 
ATOM   3508  C  CD1   . ILE C 2 40  ? 47.268  77.053  49.195  1.00 15.00  ? 40   ILE A CD1   1 
ATOM   3509  N  N     . GLU C 2 41  ? 46.157  81.352  50.688  1.00 26.57  ? 41   GLU A N     1 
ATOM   3510  C  CA    . GLU C 2 41  ? 45.935  82.636  51.345  1.00 36.67  ? 41   GLU A CA    1 
ATOM   3511  C  C     . GLU C 2 41  ? 46.642  82.724  52.691  1.00 25.72  ? 41   GLU A C     1 
ATOM   3512  O  O     . GLU C 2 41  ? 46.016  82.677  53.741  1.00 23.16  ? 41   GLU A O     1 
ATOM   3513  C  CB    . GLU C 2 41  ? 44.408  82.816  51.456  1.00 37.69  ? 41   GLU A CB    1 
ATOM   3514  C  CG    . GLU C 2 41  ? 43.900  84.179  51.085  1.00 54.50  ? 41   GLU A CG    1 
ATOM   3515  C  CD    . GLU C 2 41  ? 42.653  84.157  50.213  1.00 52.02  ? 41   GLU A CD    1 
ATOM   3516  O  OE1   . GLU C 2 41  ? 42.800  84.066  48.972  1.00 41.71  ? 41   GLU A OE1   1 
ATOM   3517  O  OE2   . GLU C 2 41  ? 41.537  84.233  50.774  1.00 40.83  ? 41   GLU A OE2   1 
ATOM   3518  N  N     . ASP C 2 42  ? 47.964  82.829  52.640  1.00 30.50  ? 42   ASP A N     1 
ATOM   3519  C  CA    . ASP C 2 42  ? 48.794  82.882  53.838  1.00 21.92  ? 42   ASP A CA    1 
ATOM   3520  C  C     . ASP C 2 42  ? 49.198  84.310  54.239  1.00 32.78  ? 42   ASP A C     1 
ATOM   3521  O  O     . ASP C 2 42  ? 50.380  84.682  54.205  1.00 30.53  ? 42   ASP A O     1 
ATOM   3522  C  CB    . ASP C 2 42  ? 50.041  82.022  53.630  1.00 25.98  ? 42   ASP A CB    1 
ATOM   3523  C  CG    . ASP C 2 42  ? 50.892  82.452  52.416  1.00 28.47  ? 42   ASP A CG    1 
ATOM   3524  O  OD1   . ASP C 2 42  ? 52.049  81.979  52.338  1.00 32.92  ? 42   ASP A OD1   1 
ATOM   3525  O  OD2   . ASP C 2 42  ? 50.443  83.235  51.534  1.00 26.24  ? 42   ASP A OD2   1 
ATOM   3526  N  N     . THR C 2 43  ? 48.214  85.100  54.658  1.00 34.58  ? 43   THR A N     1 
ATOM   3527  C  CA    . THR C 2 43  ? 48.453  86.492  55.028  1.00 32.26  ? 43   THR A CA    1 
ATOM   3528  C  C     . THR C 2 43  ? 48.579  86.750  56.528  1.00 27.93  ? 43   THR A C     1 
ATOM   3529  O  O     . THR C 2 43  ? 48.935  87.844  56.939  1.00 28.44  ? 43   THR A O     1 
ATOM   3530  C  CB    . THR C 2 43  ? 47.341  87.402  54.470  1.00 33.01  ? 43   THR A CB    1 
ATOM   3531  O  OG1   . THR C 2 43  ? 46.056  86.941  54.929  1.00 30.98  ? 43   THR A OG1   1 
ATOM   3532  C  CG2   . THR C 2 43  ? 47.357  87.387  52.955  1.00 33.94  ? 43   THR A CG2   1 
ATOM   3533  N  N     . ASP C 2 44  ? 48.300  85.742  57.337  1.00 26.54  ? 44   ASP A N     1 
ATOM   3534  C  CA    . ASP C 2 44  ? 48.368  85.882  58.798  1.00 32.88  ? 44   ASP A CA    1 
ATOM   3535  C  C     . ASP C 2 44  ? 49.520  85.057  59.402  1.00 37.71  ? 44   ASP A C     1 
ATOM   3536  O  O     . ASP C 2 44  ? 49.350  83.856  59.667  1.00 38.28  ? 44   ASP A O     1 
ATOM   3537  C  CB    . ASP C 2 44  ? 47.038  85.407  59.399  1.00 37.31  ? 44   ASP A CB    1 
ATOM   3538  C  CG    . ASP C 2 44  ? 46.993  85.522  60.932  1.00 45.89  ? 44   ASP A CG    1 
ATOM   3539  O  OD1   . ASP C 2 44  ? 45.887  85.386  61.492  1.00 50.88  ? 44   ASP A OD1   1 
ATOM   3540  O  OD2   . ASP C 2 44  ? 48.039  85.736  61.583  1.00 39.31  ? 44   ASP A OD2   1 
ATOM   3541  N  N     . ARG C 2 45  ? 50.670  85.687  59.646  1.00 42.56  ? 45   ARG A N     1 
ATOM   3542  C  CA    . ARG C 2 45  ? 51.819  84.964  60.196  1.00 43.98  ? 45   ARG A CA    1 
ATOM   3543  C  C     . ARG C 2 45  ? 51.616  84.376  61.583  1.00 40.81  ? 45   ARG A C     1 
ATOM   3544  O  O     . ARG C 2 45  ? 52.287  83.421  61.959  1.00 52.44  ? 45   ARG A O     1 
ATOM   3545  C  CB    . ARG C 2 45  ? 53.076  85.844  60.137  1.00 50.72  ? 45   ARG A CB    1 
ATOM   3546  C  CG    . ARG C 2 45  ? 52.870  87.317  60.399  1.00 53.70  ? 45   ARG A CG    1 
ATOM   3547  C  CD    . ARG C 2 45  ? 54.054  88.144  59.884  1.00 56.83  ? 45   ARG A CD    1 
ATOM   3548  N  NE    . ARG C 2 45  ? 54.079  89.480  60.485  1.00 63.81  ? 45   ARG A NE    1 
ATOM   3549  C  CZ    . ARG C 2 45  ? 54.415  89.719  61.753  1.00 66.72  ? 45   ARG A CZ    1 
ATOM   3550  N  NH1   . ARG C 2 45  ? 54.763  88.713  62.546  1.00 67.17  ? 45   ARG A NH1   1 
ATOM   3551  N  NH2   . ARG C 2 45  ? 54.376  90.955  62.243  1.00 63.54  ? 45   ARG A NH2   1 
ATOM   3552  N  N     . ALA C 2 46  ? 50.659  84.913  62.325  1.00 44.23  ? 46   ALA A N     1 
ATOM   3553  C  CA    . ALA C 2 46  ? 50.364  84.416  63.662  1.00 44.46  ? 46   ALA A CA    1 
ATOM   3554  C  C     . ALA C 2 46  ? 49.741  83.013  63.643  1.00 39.54  ? 46   ALA A C     1 
ATOM   3555  O  O     . ALA C 2 46  ? 50.147  82.133  64.402  1.00 37.91  ? 46   ALA A O     1 
ATOM   3556  C  CB    . ALA C 2 46  ? 49.429  85.407  64.393  1.00 36.89  ? 46   ALA A CB    1 
ATOM   3557  N  N     . ARG C 2 47  ? 48.760  82.798  62.773  1.00 46.18  ? 47   ARG A N     1 
ATOM   3558  C  CA    . ARG C 2 47  ? 48.095  81.498  62.722  1.00 45.09  ? 47   ARG A CA    1 
ATOM   3559  C  C     . ARG C 2 47  ? 48.719  80.549  61.713  1.00 43.91  ? 47   ARG A C     1 
ATOM   3560  O  O     . ARG C 2 47  ? 48.276  79.399  61.576  1.00 41.45  ? 47   ARG A O     1 
ATOM   3561  C  CB    . ARG C 2 47  ? 46.608  81.666  62.407  1.00 39.85  ? 47   ARG A CB    1 
ATOM   3562  C  CG    . ARG C 2 47  ? 45.882  82.628  63.325  1.00 50.22  ? 47   ARG A CG    1 
ATOM   3563  C  CD    . ARG C 2 47  ? 44.382  82.310  63.379  1.00 62.33  ? 47   ARG A CD    1 
ATOM   3564  N  NE    . ARG C 2 47  ? 43.711  82.449  62.088  1.00 68.58  ? 47   ARG A NE    1 
ATOM   3565  C  CZ    . ARG C 2 47  ? 42.898  81.536  61.562  1.00 77.04  ? 47   ARG A CZ    1 
ATOM   3566  N  NH1   . ARG C 2 47  ? 42.647  80.403  62.212  1.00 70.71  ? 47   ARG A NH1   1 
ATOM   3567  N  NH2   . ARG C 2 47  ? 42.328  81.759  60.380  1.00 81.39  ? 47   ARG A NH2   1 
ATOM   3568  N  N     . TYR C 2 48  ? 49.744  81.018  61.010  1.00 31.56  ? 48   TYR A N     1 
ATOM   3569  C  CA    . TYR C 2 48  ? 50.398  80.174  60.014  1.00 34.31  ? 48   TYR A CA    1 
ATOM   3570  C  C     . TYR C 2 48  ? 51.012  78.901  60.576  1.00 34.82  ? 48   TYR A C     1 
ATOM   3571  O  O     . TYR C 2 48  ? 51.798  78.929  61.519  1.00 37.51  ? 48   TYR A O     1 
ATOM   3572  C  CB    . TYR C 2 48  ? 51.498  80.933  59.281  1.00 33.79  ? 48   TYR A CB    1 
ATOM   3573  C  CG    . TYR C 2 48  ? 52.118  80.134  58.164  1.00 31.84  ? 48   TYR A CG    1 
ATOM   3574  C  CD1   . TYR C 2 48  ? 53.329  79.456  58.342  1.00 36.29  ? 48   TYR A CD1   1 
ATOM   3575  C  CD2   . TYR C 2 48  ? 51.502  80.078  56.915  1.00 31.54  ? 48   TYR A CD2   1 
ATOM   3576  C  CE1   . TYR C 2 48  ? 53.915  78.751  57.296  1.00 29.71  ? 48   TYR A CE1   1 
ATOM   3577  C  CE2   . TYR C 2 48  ? 52.062  79.390  55.878  1.00 39.05  ? 48   TYR A CE2   1 
ATOM   3578  C  CZ    . TYR C 2 48  ? 53.273  78.725  56.069  1.00 40.70  ? 48   TYR A CZ    1 
ATOM   3579  O  OH    . TYR C 2 48  ? 53.807  78.037  55.013  1.00 44.73  ? 48   TYR A OH    1 
ATOM   3580  N  N     . VAL C 2 49  ? 50.640  77.785  59.974  1.00 27.68  ? 49   VAL A N     1 
ATOM   3581  C  CA    . VAL C 2 49  ? 51.142  76.489  60.362  1.00 28.16  ? 49   VAL A CA    1 
ATOM   3582  C  C     . VAL C 2 49  ? 52.054  75.956  59.236  1.00 38.26  ? 49   VAL A C     1 
ATOM   3583  O  O     . VAL C 2 49  ? 51.570  75.558  58.172  1.00 37.49  ? 49   VAL A O     1 
ATOM   3584  C  CB    . VAL C 2 49  ? 49.982  75.502  60.558  1.00 27.60  ? 49   VAL A CB    1 
ATOM   3585  C  CG1   . VAL C 2 49  ? 50.528  74.109  60.860  1.00 20.35  ? 49   VAL A CG1   1 
ATOM   3586  C  CG2   . VAL C 2 49  ? 49.075  75.977  61.675  1.00 31.85  ? 49   VAL A CG2   1 
ATOM   3587  N  N     . PRO C 2 50  ? 53.380  75.975  59.443  1.00 34.60  ? 50   PRO A N     1 
ATOM   3588  C  CA    . PRO C 2 50  ? 54.288  75.472  58.404  1.00 38.34  ? 50   PRO A CA    1 
ATOM   3589  C  C     . PRO C 2 50  ? 53.948  74.021  58.064  1.00 35.98  ? 50   PRO A C     1 
ATOM   3590  O  O     . PRO C 2 50  ? 53.745  73.216  58.966  1.00 37.75  ? 50   PRO A O     1 
ATOM   3591  C  CB    . PRO C 2 50  ? 55.679  75.627  59.036  1.00 40.11  ? 50   PRO A CB    1 
ATOM   3592  C  CG    . PRO C 2 50  ? 55.410  75.847  60.507  1.00 39.25  ? 50   PRO A CG    1 
ATOM   3593  C  CD    . PRO C 2 50  ? 54.125  76.603  60.543  1.00 39.18  ? 50   PRO A CD    1 
ATOM   3594  N  N     . GLY C 2 51  ? 53.859  73.705  56.768  1.00 34.53  ? 51   GLY A N     1 
ATOM   3595  C  CA    . GLY C 2 51  ? 53.509  72.359  56.347  1.00 22.07  ? 51   GLY A CA    1 
ATOM   3596  C  C     . GLY C 2 51  ? 52.037  72.192  56.010  1.00 27.79  ? 51   GLY A C     1 
ATOM   3597  O  O     . GLY C 2 51  ? 51.639  71.204  55.400  1.00 32.00  ? 51   GLY A O     1 
ATOM   3598  N  N     . ALA C 2 52  ? 51.212  73.151  56.416  1.00 25.75  ? 52   ALA A N     1 
ATOM   3599  C  CA    . ALA C 2 52  ? 49.786  73.062  56.141  1.00 33.30  ? 52   ALA A CA    1 
ATOM   3600  C  C     . ALA C 2 52  ? 49.468  73.189  54.648  1.00 27.07  ? 52   ALA A C     1 
ATOM   3601  O  O     . ALA C 2 52  ? 48.588  72.492  54.143  1.00 27.08  ? 52   ALA A O     1 
ATOM   3602  C  CB    . ALA C 2 52  ? 49.030  74.137  56.922  1.00 29.11  ? 52   ALA A CB    1 
ATOM   3603  N  N     . GLU C 2 53  ? 50.182  74.075  53.955  1.00 22.76  ? 53   GLU A N     1 
ATOM   3604  C  CA    . GLU C 2 53  ? 49.958  74.289  52.530  1.00 26.34  ? 53   GLU A CA    1 
ATOM   3605  C  C     . GLU C 2 53  ? 50.099  72.986  51.723  1.00 32.18  ? 53   GLU A C     1 
ATOM   3606  O  O     . GLU C 2 53  ? 49.163  72.607  51.010  1.00 30.66  ? 53   GLU A O     1 
ATOM   3607  C  CB    . GLU C 2 53  ? 50.910  75.371  51.986  1.00 24.73  ? 53   GLU A CB    1 
ATOM   3608  C  CG    . GLU C 2 53  ? 50.980  75.377  50.460  1.00 34.14  ? 53   GLU A CG    1 
ATOM   3609  C  CD    . GLU C 2 53  ? 51.705  76.580  49.873  1.00 45.32  ? 53   GLU A CD    1 
ATOM   3610  O  OE1   . GLU C 2 53  ? 52.052  76.516  48.669  1.00 42.89  ? 53   GLU A OE1   1 
ATOM   3611  O  OE2   . GLU C 2 53  ? 51.925  77.584  50.593  1.00 44.71  ? 53   GLU A OE2   1 
ATOM   3612  N  N     . GLU C 2 54  ? 51.246  72.303  51.838  1.00 32.65  ? 54   GLU A N     1 
ATOM   3613  C  CA    . GLU C 2 54  ? 51.467  71.028  51.120  1.00 38.65  ? 54   GLU A CA    1 
ATOM   3614  C  C     . GLU C 2 54  ? 50.373  70.027  51.435  1.00 29.63  ? 54   GLU A C     1 
ATOM   3615  O  O     . GLU C 2 54  ? 49.948  69.266  50.577  1.00 29.49  ? 54   GLU A O     1 
ATOM   3616  C  CB    . GLU C 2 54  ? 52.769  70.327  51.531  1.00 29.78  ? 54   GLU A CB    1 
ATOM   3617  C  CG    . GLU C 2 54  ? 53.998  71.157  51.498  1.00 50.58  ? 54   GLU A CG    1 
ATOM   3618  C  CD    . GLU C 2 54  ? 54.373  71.676  52.866  1.00 47.36  ? 54   GLU A CD    1 
ATOM   3619  O  OE1   . GLU C 2 54  ? 53.849  72.748  53.248  1.00 55.42  ? 54   GLU A OE1   1 
ATOM   3620  O  OE2   . GLU C 2 54  ? 55.177  71.000  53.553  1.00 40.00  ? 54   GLU A OE2   1 
ATOM   3621  N  N     . ARG C 2 55  ? 49.955  70.009  52.693  1.00 30.62  ? 55   ARG A N     1 
ATOM   3622  C  CA    . ARG C 2 55  ? 48.941  69.069  53.121  1.00 33.34  ? 55   ARG A CA    1 
ATOM   3623  C  C     . ARG C 2 55  ? 47.588  69.332  52.485  1.00 31.66  ? 55   ARG A C     1 
ATOM   3624  O  O     . ARG C 2 55  ? 46.928  68.388  52.067  1.00 30.89  ? 55   ARG A O     1 
ATOM   3625  C  CB    . ARG C 2 55  ? 48.862  69.037  54.647  1.00 31.38  ? 55   ARG A CB    1 
ATOM   3626  C  CG    . ARG C 2 55  ? 50.134  68.407  55.285  1.00 35.75  ? 55   ARG A CG    1 
ATOM   3627  C  CD    . ARG C 2 55  ? 50.239  68.650  56.815  1.00 28.44  ? 55   ARG A CD    1 
ATOM   3628  N  NE    . ARG C 2 55  ? 49.143  67.986  57.513  1.00 32.67  ? 55   ARG A NE    1 
ATOM   3629  C  CZ    . ARG C 2 55  ? 48.522  68.462  58.587  1.00 40.96  ? 55   ARG A CZ    1 
ATOM   3630  N  NH1   . ARG C 2 55  ? 48.882  69.632  59.116  1.00 42.27  ? 55   ARG A NH1   1 
ATOM   3631  N  NH2   . ARG C 2 55  ? 47.528  67.760  59.123  1.00 31.73  ? 55   ARG A NH2   1 
ATOM   3632  N  N     . ILE C 2 56  ? 47.174  70.592  52.368  1.00 30.72  ? 56   ILE A N     1 
ATOM   3633  C  CA    . ILE C 2 56  ? 45.882  70.847  51.732  1.00 27.22  ? 56   ILE A CA    1 
ATOM   3634  C  C     . ILE C 2 56  ? 45.973  70.542  50.211  1.00 28.20  ? 56   ILE A C     1 
ATOM   3635  O  O     . ILE C 2 56  ? 45.053  69.958  49.635  1.00 28.56  ? 56   ILE A O     1 
ATOM   3636  C  CB    . ILE C 2 56  ? 45.386  72.303  52.003  1.00 25.27  ? 56   ILE A CB    1 
ATOM   3637  C  CG1   . ILE C 2 56  ? 44.012  72.537  51.348  1.00 33.30  ? 56   ILE A CG1   1 
ATOM   3638  C  CG2   . ILE C 2 56  ? 46.312  73.281  51.398  1.00 37.94  ? 56   ILE A CG2   1 
ATOM   3639  C  CD1   . ILE C 2 56  ? 42.905  71.555  51.795  1.00 30.55  ? 56   ILE A CD1   1 
ATOM   3640  N  N     . LEU C 2 57  ? 47.090  70.892  49.567  1.00 27.78  ? 57   LEU A N     1 
ATOM   3641  C  CA    . LEU C 2 57  ? 47.257  70.600  48.134  1.00 25.08  ? 57   LEU A CA    1 
ATOM   3642  C  C     . LEU C 2 57  ? 47.212  69.103  47.868  1.00 26.17  ? 57   LEU A C     1 
ATOM   3643  O  O     . LEU C 2 57  ? 46.553  68.657  46.933  1.00 31.70  ? 57   LEU A O     1 
ATOM   3644  C  CB    . LEU C 2 57  ? 48.568  71.204  47.603  1.00 25.52  ? 57   LEU A CB    1 
ATOM   3645  C  CG    . LEU C 2 57  ? 48.523  72.738  47.684  1.00 30.09  ? 57   LEU A CG    1 
ATOM   3646  C  CD1   . LEU C 2 57  ? 49.830  73.311  47.247  1.00 28.29  ? 57   LEU A CD1   1 
ATOM   3647  C  CD2   . LEU C 2 57  ? 47.348  73.282  46.827  1.00 25.47  ? 57   LEU A CD2   1 
ATOM   3648  N  N     . ALA C 2 58  ? 47.894  68.322  48.698  1.00 22.07  ? 58   ALA A N     1 
ATOM   3649  C  CA    . ALA C 2 58  ? 47.882  66.868  48.528  1.00 27.24  ? 58   ALA A CA    1 
ATOM   3650  C  C     . ALA C 2 58  ? 46.484  66.284  48.734  1.00 26.93  ? 58   ALA A C     1 
ATOM   3651  O  O     . ALA C 2 58  ? 46.082  65.370  48.011  1.00 30.28  ? 58   ALA A O     1 
ATOM   3652  C  CB    . ALA C 2 58  ? 48.851  66.202  49.497  1.00 22.05  ? 58   ALA A CB    1 
ATOM   3653  N  N     . ALA C 2 59  ? 45.751  66.806  49.715  1.00 27.92  ? 59   ALA A N     1 
ATOM   3654  C  CA    . ALA C 2 59  ? 44.402  66.317  50.008  1.00 28.39  ? 59   ALA A CA    1 
ATOM   3655  C  C     . ALA C 2 59  ? 43.396  66.575  48.877  1.00 30.37  ? 59   ALA A C     1 
ATOM   3656  O  O     . ALA C 2 59  ? 42.488  65.764  48.665  1.00 36.27  ? 59   ALA A O     1 
ATOM   3657  C  CB    . ALA C 2 59  ? 43.904  66.920  51.294  1.00 24.70  ? 59   ALA A CB    1 
ATOM   3658  N  N     . LEU C 2 60  ? 43.549  67.695  48.163  1.00 29.27  ? 60   LEU A N     1 
ATOM   3659  C  CA    . LEU C 2 60  ? 42.653  68.019  47.043  1.00 28.52  ? 60   LEU A CA    1 
ATOM   3660  C  C     . LEU C 2 60  ? 42.925  67.035  45.917  1.00 28.07  ? 60   LEU A C     1 
ATOM   3661  O  O     . LEU C 2 60  ? 41.999  66.532  45.284  1.00 33.87  ? 60   LEU A O     1 
ATOM   3662  C  CB    . LEU C 2 60  ? 42.877  69.449  46.544  1.00 27.13  ? 60   LEU A CB    1 
ATOM   3663  C  CG    . LEU C 2 60  ? 42.422  70.476  47.594  1.00 34.54  ? 60   LEU A CG    1 
ATOM   3664  C  CD1   . LEU C 2 60  ? 42.830  71.862  47.198  1.00 29.95  ? 60   LEU A CD1   1 
ATOM   3665  C  CD2   . LEU C 2 60  ? 40.935  70.414  47.769  1.00 31.10  ? 60   LEU A CD2   1 
ATOM   3666  N  N     . LYS C 2 61  ? 44.201  66.732  45.692  1.00 28.02  ? 61   LYS A N     1 
ATOM   3667  C  CA    . LYS C 2 61  ? 44.566  65.783  44.657  1.00 28.42  ? 61   LYS A CA    1 
ATOM   3668  C  C     . LYS C 2 61  ? 44.090  64.384  45.068  1.00 32.56  ? 61   LYS A C     1 
ATOM   3669  O  O     . LYS C 2 61  ? 43.519  63.658  44.260  1.00 31.29  ? 61   LYS A O     1 
ATOM   3670  C  CB    . LYS C 2 61  ? 46.076  65.816  44.427  1.00 30.61  ? 61   LYS A CB    1 
ATOM   3671  C  CG    . LYS C 2 61  ? 46.560  67.139  43.803  1.00 26.81  ? 61   LYS A CG    1 
ATOM   3672  C  CD    . LYS C 2 61  ? 47.999  67.018  43.396  1.00 33.76  ? 61   LYS A CD    1 
ATOM   3673  C  CE    . LYS C 2 61  ? 48.719  68.363  43.384  1.00 40.88  ? 61   LYS A CE    1 
ATOM   3674  N  NZ    . LYS C 2 61  ? 49.095  68.725  44.781  1.00 39.87  ? 61   LYS A NZ    1 
ATOM   3675  N  N     . TRP C 2 62  ? 44.287  64.044  46.339  1.00 24.86  ? 62   TRP A N     1 
ATOM   3676  C  CA    . TRP C 2 62  ? 43.871  62.754  46.878  1.00 25.17  ? 62   TRP A CA    1 
ATOM   3677  C  C     . TRP C 2 62  ? 42.374  62.566  46.650  1.00 30.94  ? 62   TRP A C     1 
ATOM   3678  O  O     . TRP C 2 62  ? 41.947  61.520  46.185  1.00 25.26  ? 62   TRP A O     1 
ATOM   3679  C  CB    . TRP C 2 62  ? 44.170  62.701  48.371  1.00 22.41  ? 62   TRP A CB    1 
ATOM   3680  C  CG    . TRP C 2 62  ? 43.662  61.486  49.035  1.00 25.54  ? 62   TRP A CG    1 
ATOM   3681  C  CD1   . TRP C 2 62  ? 44.130  60.204  48.878  1.00 23.17  ? 62   TRP A CD1   1 
ATOM   3682  C  CD2   . TRP C 2 62  ? 42.582  61.407  49.965  1.00 24.44  ? 62   TRP A CD2   1 
ATOM   3683  N  NE1   . TRP C 2 62  ? 43.407  59.336  49.651  1.00 26.74  ? 62   TRP A NE1   1 
ATOM   3684  C  CE2   . TRP C 2 62  ? 42.447  60.039  50.333  1.00 32.50  ? 62   TRP A CE2   1 
ATOM   3685  C  CE3   . TRP C 2 62  ? 41.710  62.354  50.530  1.00 29.96  ? 62   TRP A CE3   1 
ATOM   3686  C  CZ2   . TRP C 2 62  ? 41.472  59.591  51.245  1.00 26.33  ? 62   TRP A CZ2   1 
ATOM   3687  C  CZ3   . TRP C 2 62  ? 40.732  61.910  51.447  1.00 25.45  ? 62   TRP A CZ3   1 
ATOM   3688  C  CH2   . TRP C 2 62  ? 40.629  60.534  51.791  1.00 32.97  ? 62   TRP A CH2   1 
ATOM   3689  N  N     . LEU C 2 63  ? 41.596  63.597  46.975  1.00 23.70  ? 63   LEU A N     1 
ATOM   3690  C  CA    . LEU C 2 63  ? 40.136  63.577  46.823  1.00 33.23  ? 63   LEU A CA    1 
ATOM   3691  C  C     . LEU C 2 63  ? 39.676  63.427  45.363  1.00 34.23  ? 63   LEU A C     1 
ATOM   3692  O  O     . LEU C 2 63  ? 38.523  63.057  45.112  1.00 34.56  ? 63   LEU A O     1 
ATOM   3693  C  CB    . LEU C 2 63  ? 39.559  64.859  47.411  1.00 23.04  ? 63   LEU A CB    1 
ATOM   3694  C  CG    . LEU C 2 63  ? 38.360  64.790  48.342  1.00 34.84  ? 63   LEU A CG    1 
ATOM   3695  C  CD1   . LEU C 2 63  ? 37.103  65.252  47.614  1.00 34.03  ? 63   LEU A CD1   1 
ATOM   3696  C  CD2   . LEU C 2 63  ? 38.211  63.394  48.860  1.00 21.99  ? 63   LEU A CD2   1 
ATOM   3697  N  N     . GLY C 2 64  ? 40.583  63.728  44.421  1.00 28.13  ? 64   GLY A N     1 
ATOM   3698  C  CA    . GLY C 2 64  ? 40.289  63.602  43.002  1.00 20.14  ? 64   GLY A CA    1 
ATOM   3699  C  C     . GLY C 2 64  ? 40.182  64.870  42.161  1.00 30.12  ? 64   GLY A C     1 
ATOM   3700  O  O     . GLY C 2 64  ? 39.961  64.799  40.955  1.00 28.05  ? 64   GLY A O     1 
ATOM   3701  N  N     . LEU C 2 65  ? 40.342  66.035  42.774  1.00 21.72  ? 65   LEU A N     1 
ATOM   3702  C  CA    . LEU C 2 65  ? 40.231  67.272  42.041  1.00 27.63  ? 65   LEU A CA    1 
ATOM   3703  C  C     . LEU C 2 65  ? 41.564  67.556  41.398  1.00 34.83  ? 65   LEU A C     1 
ATOM   3704  O  O     . LEU C 2 65  ? 42.592  67.010  41.820  1.00 41.10  ? 65   LEU A O     1 
ATOM   3705  C  CB    . LEU C 2 65  ? 39.843  68.410  42.985  1.00 20.61  ? 65   LEU A CB    1 
ATOM   3706  C  CG    . LEU C 2 65  ? 38.668  68.005  43.899  1.00 38.13  ? 65   LEU A CG    1 
ATOM   3707  C  CD1   . LEU C 2 65  ? 38.297  69.142  44.857  1.00 36.51  ? 65   LEU A CD1   1 
ATOM   3708  C  CD2   . LEU C 2 65  ? 37.466  67.599  43.051  1.00 30.96  ? 65   LEU A CD2   1 
ATOM   3709  N  N     . SER C 2 66  ? 41.533  68.362  40.340  1.00 34.08  ? 66   SER A N     1 
ATOM   3710  C  CA    . SER C 2 66  ? 42.733  68.793  39.637  1.00 32.04  ? 66   SER A CA    1 
ATOM   3711  C  C     . SER C 2 66  ? 42.475  70.270  39.502  1.00 30.56  ? 66   SER A C     1 
ATOM   3712  O  O     . SER C 2 66  ? 41.324  70.687  39.390  1.00 29.56  ? 66   SER A O     1 
ATOM   3713  C  CB    . SER C 2 66  ? 42.822  68.214  38.212  1.00 37.96  ? 66   SER A CB    1 
ATOM   3714  O  OG    . SER C 2 66  ? 42.745  66.799  38.202  1.00 53.34  ? 66   SER A OG    1 
ATOM   3715  N  N     . TYR C 2 67  ? 43.527  71.065  39.526  1.00 25.86  ? 67   TYR A N     1 
ATOM   3716  C  CA    . TYR C 2 67  ? 43.360  72.482  39.317  1.00 27.35  ? 67   TYR A CA    1 
ATOM   3717  C  C     . TYR C 2 67  ? 44.210  72.859  38.107  1.00 27.91  ? 67   TYR A C     1 
ATOM   3718  O  O     . TYR C 2 67  ? 45.160  72.164  37.768  1.00 28.51  ? 67   TYR A O     1 
ATOM   3719  C  CB    . TYR C 2 67  ? 43.729  73.311  40.569  1.00 28.66  ? 67   TYR A CB    1 
ATOM   3720  C  CG    . TYR C 2 67  ? 44.862  72.799  41.399  1.00 23.56  ? 67   TYR A CG    1 
ATOM   3721  C  CD1   . TYR C 2 67  ? 44.678  71.741  42.273  1.00 20.01  ? 67   TYR A CD1   1 
ATOM   3722  C  CD2   . TYR C 2 67  ? 46.136  73.381  41.316  1.00 28.68  ? 67   TYR A CD2   1 
ATOM   3723  C  CE1   . TYR C 2 67  ? 45.727  71.263  43.051  1.00 21.69  ? 67   TYR A CE1   1 
ATOM   3724  C  CE2   . TYR C 2 67  ? 47.195  72.907  42.090  1.00 20.15  ? 67   TYR A CE2   1 
ATOM   3725  C  CZ    . TYR C 2 67  ? 46.972  71.848  42.956  1.00 22.64  ? 67   TYR A CZ    1 
ATOM   3726  O  OH    . TYR C 2 67  ? 47.981  71.395  43.750  1.00 29.50  ? 67   TYR A OH    1 
ATOM   3727  N  N     . ASP C 2 68  ? 43.847  73.947  37.442  1.00 24.27  ? 68   ASP A N     1 
ATOM   3728  C  CA    . ASP C 2 68  ? 44.559  74.361  36.258  1.00 21.17  ? 68   ASP A CA    1 
ATOM   3729  C  C     . ASP C 2 68  ? 45.661  75.376  36.543  1.00 30.14  ? 68   ASP A C     1 
ATOM   3730  O  O     . ASP C 2 68  ? 46.592  75.490  35.742  1.00 29.92  ? 68   ASP A O     1 
ATOM   3731  C  CB    . ASP C 2 68  ? 43.570  74.906  35.221  1.00 22.05  ? 68   ASP A CB    1 
ATOM   3732  C  CG    . ASP C 2 68  ? 42.386  73.982  35.013  1.00 25.35  ? 68   ASP A CG    1 
ATOM   3733  O  OD1   . ASP C 2 68  ? 41.209  74.404  35.195  1.00 31.10  ? 68   ASP A OD1   1 
ATOM   3734  O  OD2   . ASP C 2 68  ? 42.634  72.822  34.656  1.00 29.51  ? 68   ASP A OD2   1 
ATOM   3735  N  N     . GLU C 2 69  ? 45.557  76.127  37.646  1.00 16.02  ? 69   GLU A N     1 
ATOM   3736  C  CA    . GLU C 2 69  ? 46.610  77.072  38.020  1.00 17.84  ? 69   GLU A CA    1 
ATOM   3737  C  C     . GLU C 2 69  ? 46.803  76.978  39.536  1.00 27.31  ? 69   GLU A C     1 
ATOM   3738  O  O     . GLU C 2 69  ? 45.844  76.685  40.272  1.00 26.40  ? 69   GLU A O     1 
ATOM   3739  C  CB    . GLU C 2 69  ? 46.259  78.500  37.592  1.00 19.47  ? 69   GLU A CB    1 
ATOM   3740  C  CG    . GLU C 2 69  ? 45.940  78.628  36.090  1.00 22.96  ? 69   GLU A CG    1 
ATOM   3741  C  CD    . GLU C 2 69  ? 45.539  80.041  35.658  1.00 28.12  ? 69   GLU A CD    1 
ATOM   3742  O  OE1   . GLU C 2 69  ? 45.711  80.994  36.443  1.00 29.37  ? 69   GLU A OE1   1 
ATOM   3743  O  OE2   . GLU C 2 69  ? 45.054  80.210  34.516  1.00 35.36  ? 69   GLU A OE2   1 
ATOM   3744  N  N     . GLY C 2 70  ? 48.029  77.219  40.005  1.00 20.30  ? 70   GLY A N     1 
ATOM   3745  C  CA    . GLY C 2 70  ? 48.305  77.105  41.419  1.00 18.77  ? 70   GLY A CA    1 
ATOM   3746  C  C     . GLY C 2 70  ? 49.771  77.034  41.787  1.00 21.40  ? 70   GLY A C     1 
ATOM   3747  O  O     . GLY C 2 70  ? 50.617  76.961  40.915  1.00 26.20  ? 70   GLY A O     1 
ATOM   3748  N  N     . PRO C 2 71  ? 50.101  77.028  43.087  1.00 31.97  ? 71   PRO A N     1 
ATOM   3749  C  CA    . PRO C 2 71  ? 51.482  76.982  43.592  1.00 30.32  ? 71   PRO A CA    1 
ATOM   3750  C  C     . PRO C 2 71  ? 52.374  75.932  42.932  1.00 30.77  ? 71   PRO A C     1 
ATOM   3751  O  O     . PRO C 2 71  ? 53.516  76.220  42.573  1.00 37.64  ? 71   PRO A O     1 
ATOM   3752  C  CB    . PRO C 2 71  ? 51.306  76.689  45.088  1.00 28.82  ? 71   PRO A CB    1 
ATOM   3753  C  CG    . PRO C 2 71  ? 49.898  77.138  45.392  1.00 28.92  ? 71   PRO A CG    1 
ATOM   3754  C  CD    . PRO C 2 71  ? 49.141  76.728  44.169  1.00 32.01  ? 71   PRO A CD    1 
ATOM   3755  N  N     . ASP C 2 72  ? 51.849  74.722  42.772  1.00 23.26  ? 72   ASP A N     1 
ATOM   3756  C  CA    . ASP C 2 72  ? 52.634  73.622  42.218  1.00 28.85  ? 72   ASP A CA    1 
ATOM   3757  C  C     . ASP C 2 72  ? 52.298  73.163  40.811  1.00 23.83  ? 72   ASP A C     1 
ATOM   3758  O  O     . ASP C 2 72  ? 52.695  72.076  40.403  1.00 23.73  ? 72   ASP A O     1 
ATOM   3759  C  CB    . ASP C 2 72  ? 52.577  72.409  43.169  1.00 19.64  ? 72   ASP A CB    1 
ATOM   3760  C  CG    . ASP C 2 72  ? 51.143  72.001  43.502  1.00 38.15  ? 72   ASP A CG    1 
ATOM   3761  O  OD1   . ASP C 2 72  ? 50.188  72.736  43.110  1.00 28.59  ? 72   ASP A OD1   1 
ATOM   3762  O  OD2   . ASP C 2 72  ? 50.970  70.949  44.159  1.00 32.87  ? 72   ASP A OD2   1 
ATOM   3763  N  N     . VAL C 2 73  ? 51.573  73.974  40.060  1.00 27.36  ? 73   VAL A N     1 
ATOM   3764  C  CA    . VAL C 2 73  ? 51.254  73.596  38.695  1.00 20.43  ? 73   VAL A CA    1 
ATOM   3765  C  C     . VAL C 2 73  ? 51.477  74.789  37.772  1.00 26.59  ? 73   VAL A C     1 
ATOM   3766  O  O     . VAL C 2 73  ? 51.209  74.699  36.586  1.00 29.98  ? 73   VAL A O     1 
ATOM   3767  C  CB    . VAL C 2 73  ? 49.788  73.087  38.561  1.00 25.51  ? 73   VAL A CB    1 
ATOM   3768  C  CG1   . VAL C 2 73  ? 49.580  71.818  39.378  1.00 24.61  ? 73   VAL A CG1   1 
ATOM   3769  C  CG2   . VAL C 2 73  ? 48.821  74.167  39.005  1.00 28.77  ? 73   VAL A CG2   1 
ATOM   3770  N  N     . GLY C 2 74  ? 51.979  75.900  38.315  1.00 30.06  ? 74   GLY A N     1 
ATOM   3771  C  CA    . GLY C 2 74  ? 52.238  77.093  37.507  1.00 22.19  ? 74   GLY A CA    1 
ATOM   3772  C  C     . GLY C 2 74  ? 50.986  77.869  37.116  1.00 28.18  ? 74   GLY A C     1 
ATOM   3773  O  O     . GLY C 2 74  ? 49.901  77.659  37.681  1.00 28.28  ? 74   GLY A O     1 
ATOM   3774  N  N     . GLY C 2 75  ? 51.134  78.765  36.143  1.00 23.16  ? 75   GLY A N     1 
ATOM   3775  C  CA    . GLY C 2 75  ? 50.019  79.566  35.661  1.00 20.68  ? 75   GLY A CA    1 
ATOM   3776  C  C     . GLY C 2 75  ? 50.515  80.962  35.365  1.00 18.72  ? 75   GLY A C     1 
ATOM   3777  O  O     . GLY C 2 75  ? 51.458  81.393  35.996  1.00 25.17  ? 75   GLY A O     1 
ATOM   3778  N  N     . PRO C 2 76  ? 49.881  81.707  34.455  1.00 24.03  ? 76   PRO A N     1 
ATOM   3779  C  CA    . PRO C 2 76  ? 50.274  83.073  34.070  1.00 15.11  ? 76   PRO A CA    1 
ATOM   3780  C  C     . PRO C 2 76  ? 50.017  84.199  35.053  1.00 33.57  ? 76   PRO A C     1 
ATOM   3781  O  O     . PRO C 2 76  ? 50.454  85.335  34.820  1.00 28.38  ? 76   PRO A O     1 
ATOM   3782  C  CB    . PRO C 2 76  ? 49.501  83.310  32.773  1.00 24.73  ? 76   PRO A CB    1 
ATOM   3783  C  CG    . PRO C 2 76  ? 48.203  82.546  33.032  1.00 32.37  ? 76   PRO A CG    1 
ATOM   3784  C  CD    . PRO C 2 76  ? 48.689  81.259  33.703  1.00 26.11  ? 76   PRO A CD    1 
ATOM   3785  N  N     . HIS C 2 77  ? 49.314  83.922  36.148  1.00 33.25  ? 77   HIS A N     1 
ATOM   3786  C  CA    . HIS C 2 77  ? 49.034  84.997  37.092  1.00 29.85  ? 77   HIS A CA    1 
ATOM   3787  C  C     . HIS C 2 77  ? 49.611  84.746  38.450  1.00 25.79  ? 77   HIS A C     1 
ATOM   3788  O  O     . HIS C 2 77  ? 49.079  85.225  39.428  1.00 29.22  ? 77   HIS A O     1 
ATOM   3789  C  CB    . HIS C 2 77  ? 47.537  85.202  37.215  1.00 26.20  ? 77   HIS A CB    1 
ATOM   3790  C  CG    . HIS C 2 77  ? 46.871  85.437  35.902  1.00 42.93  ? 77   HIS A CG    1 
ATOM   3791  N  ND1   . HIS C 2 77  ? 47.152  86.535  35.115  1.00 48.58  ? 77   HIS A ND1   1 
ATOM   3792  C  CD2   . HIS C 2 77  ? 45.968  84.700  35.214  1.00 46.02  ? 77   HIS A CD2   1 
ATOM   3793  C  CE1   . HIS C 2 77  ? 46.449  86.465  33.998  1.00 45.33  ? 77   HIS A CE1   1 
ATOM   3794  N  NE2   . HIS C 2 77  ? 45.723  85.361  34.033  1.00 41.98  ? 77   HIS A NE2   1 
ATOM   3795  N  N     . GLY C 2 78  ? 50.683  83.968  38.513  1.00 31.80  ? 78   GLY A N     1 
ATOM   3796  C  CA    . GLY C 2 78  ? 51.302  83.683  39.795  1.00 28.74  ? 78   GLY A CA    1 
ATOM   3797  C  C     . GLY C 2 78  ? 51.992  84.923  40.308  1.00 28.12  ? 78   GLY A C     1 
ATOM   3798  O  O     . GLY C 2 78  ? 51.976  85.964  39.640  1.00 34.89  ? 78   GLY A O     1 
ATOM   3799  N  N     . PRO C 2 79  ? 52.588  84.859  41.495  1.00 27.10  ? 79   PRO A N     1 
ATOM   3800  C  CA    . PRO C 2 79  ? 52.628  83.661  42.332  1.00 28.53  ? 79   PRO A CA    1 
ATOM   3801  C  C     . PRO C 2 79  ? 51.223  83.392  42.850  1.00 30.52  ? 79   PRO A C     1 
ATOM   3802  O  O     . PRO C 2 79  ? 50.387  84.280  42.856  1.00 32.19  ? 79   PRO A O     1 
ATOM   3803  C  CB    . PRO C 2 79  ? 53.584  84.045  43.465  1.00 31.35  ? 79   PRO A CB    1 
ATOM   3804  C  CG    . PRO C 2 79  ? 54.339  85.232  42.955  1.00 32.94  ? 79   PRO A CG    1 
ATOM   3805  C  CD    . PRO C 2 79  ? 53.335  85.964  42.115  1.00 27.47  ? 79   PRO A CD    1 
ATOM   3806  N  N     . TYR C 2 80  ? 50.984  82.162  43.290  1.00 31.23  ? 80   TYR A N     1 
ATOM   3807  C  CA    . TYR C 2 80  ? 49.688  81.746  43.779  1.00 25.87  ? 80   TYR A CA    1 
ATOM   3808  C  C     . TYR C 2 80  ? 49.654  81.563  45.281  1.00 26.71  ? 80   TYR A C     1 
ATOM   3809  O  O     . TYR C 2 80  ? 48.856  80.807  45.797  1.00 30.41  ? 80   TYR A O     1 
ATOM   3810  C  CB    . TYR C 2 80  ? 49.275  80.453  43.084  1.00 25.04  ? 80   TYR A CB    1 
ATOM   3811  C  CG    . TYR C 2 80  ? 48.940  80.687  41.632  1.00 32.50  ? 80   TYR A CG    1 
ATOM   3812  C  CD1   . TYR C 2 80  ? 49.922  80.584  40.660  1.00 28.72  ? 80   TYR A CD1   1 
ATOM   3813  C  CD2   . TYR C 2 80  ? 47.672  81.128  41.242  1.00 26.23  ? 80   TYR A CD2   1 
ATOM   3814  C  CE1   . TYR C 2 80  ? 49.674  80.916  39.355  1.00 17.04  ? 80   TYR A CE1   1 
ATOM   3815  C  CE2   . TYR C 2 80  ? 47.407  81.473  39.919  1.00 21.14  ? 80   TYR A CE2   1 
ATOM   3816  C  CZ    . TYR C 2 80  ? 48.430  81.364  38.980  1.00 26.42  ? 80   TYR A CZ    1 
ATOM   3817  O  OH    . TYR C 2 80  ? 48.253  81.735  37.666  1.00 24.63  ? 80   TYR A OH    1 
ATOM   3818  N  N     . ARG C 2 81  ? 50.537  82.267  45.967  1.00 27.38  ? 81   ARG A N     1 
ATOM   3819  C  CA    . ARG C 2 81  ? 50.641  82.220  47.413  1.00 22.94  ? 81   ARG A CA    1 
ATOM   3820  C  C     . ARG C 2 81  ? 50.667  83.715  47.774  1.00 23.78  ? 81   ARG A C     1 
ATOM   3821  O  O     . ARG C 2 81  ? 51.542  84.439  47.323  1.00 24.66  ? 81   ARG A O     1 
ATOM   3822  C  CB    . ARG C 2 81  ? 51.964  81.526  47.756  1.00 25.67  ? 81   ARG A CB    1 
ATOM   3823  C  CG    . ARG C 2 81  ? 52.351  81.460  49.215  1.00 35.10  ? 81   ARG A CG    1 
ATOM   3824  C  CD    . ARG C 2 81  ? 53.632  80.645  49.391  1.00 28.43  ? 81   ARG A CD    1 
ATOM   3825  N  NE    . ARG C 2 81  ? 53.539  79.350  48.712  1.00 36.27  ? 81   ARG A NE    1 
ATOM   3826  C  CZ    . ARG C 2 81  ? 54.334  78.979  47.706  1.00 38.10  ? 81   ARG A CZ    1 
ATOM   3827  N  NH1   . ARG C 2 81  ? 55.280  79.803  47.274  1.00 40.91  ? 81   ARG A NH1   1 
ATOM   3828  N  NH2   . ARG C 2 81  ? 54.181  77.799  47.119  1.00 32.81  ? 81   ARG A NH2   1 
ATOM   3829  N  N     . GLN C 2 82  ? 49.734  84.182  48.591  1.00 26.55  ? 82   GLN A N     1 
ATOM   3830  C  CA    . GLN C 2 82  ? 49.691  85.617  48.894  1.00 29.40  ? 82   GLN A CA    1 
ATOM   3831  C  C     . GLN C 2 82  ? 50.885  86.211  49.639  1.00 30.72  ? 82   GLN A C     1 
ATOM   3832  O  O     . GLN C 2 82  ? 51.128  87.408  49.528  1.00 26.97  ? 82   GLN A O     1 
ATOM   3833  C  CB    . GLN C 2 82  ? 48.386  85.963  49.620  1.00 27.29  ? 82   GLN A CB    1 
ATOM   3834  C  CG    . GLN C 2 82  ? 47.175  85.440  48.884  1.00 27.30  ? 82   GLN A CG    1 
ATOM   3835  C  CD    . GLN C 2 82  ? 45.880  85.985  49.421  1.00 29.34  ? 82   GLN A CD    1 
ATOM   3836  O  OE1   . GLN C 2 82  ? 45.626  85.955  50.627  1.00 32.49  ? 82   GLN A OE1   1 
ATOM   3837  N  NE2   . GLN C 2 82  ? 45.043  86.483  48.526  1.00 28.63  ? 82   GLN A NE2   1 
ATOM   3838  N  N     . SER C 2 83  ? 51.636  85.401  50.380  1.00 23.49  ? 83   SER A N     1 
ATOM   3839  C  CA    . SER C 2 83  ? 52.791  85.957  51.085  1.00 33.61  ? 83   SER A CA    1 
ATOM   3840  C  C     . SER C 2 83  ? 53.839  86.512  50.110  1.00 26.77  ? 83   SER A C     1 
ATOM   3841  O  O     . SER C 2 83  ? 54.600  87.403  50.463  1.00 35.01  ? 83   SER A O     1 
ATOM   3842  C  CB    . SER C 2 83  ? 53.428  84.906  52.003  1.00 29.41  ? 83   SER A CB    1 
ATOM   3843  O  OG    . SER C 2 83  ? 53.738  83.742  51.273  1.00 27.76  ? 83   SER A OG    1 
ATOM   3844  N  N     . GLU C 2 84  ? 53.846  86.003  48.882  1.00 26.14  ? 84   GLU A N     1 
ATOM   3845  C  CA    . GLU C 2 84  ? 54.772  86.463  47.838  1.00 26.61  ? 84   GLU A CA    1 
ATOM   3846  C  C     . GLU C 2 84  ? 54.220  87.587  46.962  1.00 26.17  ? 84   GLU A C     1 
ATOM   3847  O  O     . GLU C 2 84  ? 54.823  87.962  45.968  1.00 29.50  ? 84   GLU A O     1 
ATOM   3848  C  CB    . GLU C 2 84  ? 55.150  85.285  46.955  1.00 24.96  ? 84   GLU A CB    1 
ATOM   3849  C  CG    . GLU C 2 84  ? 56.115  84.353  47.678  1.00 38.87  ? 84   GLU A CG    1 
ATOM   3850  C  CD    . GLU C 2 84  ? 56.197  82.969  47.074  1.00 37.82  ? 84   GLU A CD    1 
ATOM   3851  O  OE1   . GLU C 2 84  ? 56.278  82.856  45.830  1.00 32.41  ? 84   GLU A OE1   1 
ATOM   3852  O  OE2   . GLU C 2 84  ? 56.187  81.996  47.865  1.00 45.57  ? 84   GLU A OE2   1 
ATOM   3853  N  N     . ARG C 2 85  ? 53.066  88.126  47.324  1.00 28.60  ? 85   ARG A N     1 
ATOM   3854  C  CA    . ARG C 2 85  ? 52.455  89.179  46.527  1.00 25.96  ? 85   ARG A CA    1 
ATOM   3855  C  C     . ARG C 2 85  ? 52.369  90.507  47.298  1.00 30.56  ? 85   ARG A C     1 
ATOM   3856  O  O     . ARG C 2 85  ? 51.788  91.489  46.808  1.00 29.19  ? 85   ARG A O     1 
ATOM   3857  C  CB    . ARG C 2 85  ? 51.045  88.730  46.094  1.00 24.95  ? 85   ARG A CB    1 
ATOM   3858  C  CG    . ARG C 2 85  ? 50.999  87.458  45.184  1.00 21.76  ? 85   ARG A CG    1 
ATOM   3859  C  CD    . ARG C 2 85  ? 49.543  86.905  44.979  1.00 21.18  ? 85   ARG A CD    1 
ATOM   3860  N  NE    . ARG C 2 85  ? 48.742  87.741  44.082  1.00 20.98  ? 85   ARG A NE    1 
ATOM   3861  C  CZ    . ARG C 2 85  ? 48.850  87.739  42.753  1.00 30.98  ? 85   ARG A CZ    1 
ATOM   3862  N  NH1   . ARG C 2 85  ? 49.725  86.942  42.117  1.00 22.85  ? 85   ARG A NH1   1 
ATOM   3863  N  NH2   . ARG C 2 85  ? 48.085  88.540  42.048  1.00 25.57  ? 85   ARG A NH2   1 
ATOM   3864  N  N     . LEU C 2 86  ? 52.980  90.547  48.483  1.00 25.21  ? 86   LEU A N     1 
ATOM   3865  C  CA    . LEU C 2 86  ? 52.911  91.730  49.335  1.00 28.59  ? 86   LEU A CA    1 
ATOM   3866  C  C     . LEU C 2 86  ? 53.027  93.057  48.632  1.00 26.46  ? 86   LEU A C     1 
ATOM   3867  O  O     . LEU C 2 86  ? 52.157  93.902  48.777  1.00 32.14  ? 86   LEU A O     1 
ATOM   3868  C  CB    . LEU C 2 86  ? 53.933  91.644  50.487  1.00 28.42  ? 86   LEU A CB    1 
ATOM   3869  C  CG    . LEU C 2 86  ? 53.415  90.925  51.753  1.00 33.16  ? 86   LEU A CG    1 
ATOM   3870  C  CD1   . LEU C 2 86  ? 52.520  89.779  51.365  1.00 27.22  ? 86   LEU A CD1   1 
ATOM   3871  C  CD2   . LEU C 2 86  ? 54.560  90.416  52.612  1.00 39.67  ? 86   LEU A CD2   1 
ATOM   3872  N  N     . PRO C 2 87  ? 54.078  93.251  47.830  1.00 31.46  ? 87   PRO A N     1 
ATOM   3873  C  CA    . PRO C 2 87  ? 54.194  94.551  47.151  1.00 28.34  ? 87   PRO A CA    1 
ATOM   3874  C  C     . PRO C 2 87  ? 52.945  94.929  46.344  1.00 31.15  ? 87   PRO A C     1 
ATOM   3875  O  O     . PRO C 2 87  ? 52.606  96.113  46.190  1.00 26.61  ? 87   PRO A O     1 
ATOM   3876  C  CB    . PRO C 2 87  ? 55.435  94.384  46.269  1.00 26.64  ? 87   PRO A CB    1 
ATOM   3877  C  CG    . PRO C 2 87  ? 56.266  93.325  47.046  1.00 25.39  ? 87   PRO A CG    1 
ATOM   3878  C  CD    . PRO C 2 87  ? 55.202  92.349  47.488  1.00 26.34  ? 87   PRO A CD    1 
ATOM   3879  N  N     . LEU C 2 88  ? 52.237  93.936  45.839  1.00 24.01  ? 88   LEU A N     1 
ATOM   3880  C  CA    . LEU C 2 88  ? 51.046  94.252  45.073  1.00 24.07  ? 88   LEU A CA    1 
ATOM   3881  C  C     . LEU C 2 88  ? 49.961  94.909  45.946  1.00 25.18  ? 88   LEU A C     1 
ATOM   3882  O  O     . LEU C 2 88  ? 49.457  95.976  45.606  1.00 25.95  ? 88   LEU A O     1 
ATOM   3883  C  CB    . LEU C 2 88  ? 50.508  92.979  44.444  1.00 32.68  ? 88   LEU A CB    1 
ATOM   3884  C  CG    . LEU C 2 88  ? 49.974  93.031  43.019  1.00 40.57  ? 88   LEU A CG    1 
ATOM   3885  C  CD1   . LEU C 2 88  ? 50.961  93.697  42.113  1.00 35.82  ? 88   LEU A CD1   1 
ATOM   3886  C  CD2   . LEU C 2 88  ? 49.731  91.587  42.544  1.00 51.03  ? 88   LEU A CD2   1 
ATOM   3887  N  N     . TYR C 2 89  ? 49.611  94.287  47.071  1.00 20.36  ? 89   TYR A N     1 
ATOM   3888  C  CA    . TYR C 2 89  ? 48.550  94.828  47.935  1.00 26.97  ? 89   TYR A CA    1 
ATOM   3889  C  C     . TYR C 2 89  ? 48.948  96.218  48.404  1.00 30.00  ? 89   TYR A C     1 
ATOM   3890  O  O     . TYR C 2 89  ? 48.142  97.158  48.392  1.00 28.48  ? 89   TYR A O     1 
ATOM   3891  C  CB    . TYR C 2 89  ? 48.305  93.896  49.129  1.00 31.47  ? 89   TYR A CB    1 
ATOM   3892  C  CG    . TYR C 2 89  ? 48.216  92.439  48.714  1.00 29.57  ? 89   TYR A CG    1 
ATOM   3893  C  CD1   . TYR C 2 89  ? 47.331  92.041  47.714  1.00 23.51  ? 89   TYR A CD1   1 
ATOM   3894  C  CD2   . TYR C 2 89  ? 49.066  91.461  49.282  1.00 33.28  ? 89   TYR A CD2   1 
ATOM   3895  C  CE1   . TYR C 2 89  ? 47.285  90.714  47.272  1.00 20.78  ? 89   TYR A CE1   1 
ATOM   3896  C  CE2   . TYR C 2 89  ? 49.028  90.116  48.846  1.00 19.72  ? 89   TYR A CE2   1 
ATOM   3897  C  CZ    . TYR C 2 89  ? 48.133  89.760  47.833  1.00 24.13  ? 89   TYR A CZ    1 
ATOM   3898  O  OH    . TYR C 2 89  ? 48.109  88.471  47.332  1.00 33.40  ? 89   TYR A OH    1 
ATOM   3899  N  N     . GLN C 2 90  ? 50.211  96.333  48.796  1.00 32.73  ? 90   GLN A N     1 
ATOM   3900  C  CA    . GLN C 2 90  ? 50.800  97.589  49.222  1.00 36.44  ? 90   GLN A CA    1 
ATOM   3901  C  C     . GLN C 2 90  ? 50.433  98.654  48.211  1.00 39.04  ? 90   GLN A C     1 
ATOM   3902  O  O     . GLN C 2 90  ? 49.877  99.707  48.559  1.00 38.47  ? 90   GLN A O     1 
ATOM   3903  C  CB    . GLN C 2 90  ? 52.315  97.454  49.258  1.00 41.47  ? 90   GLN A CB    1 
ATOM   3904  C  CG    . GLN C 2 90  ? 52.863  97.361  50.643  1.00 60.05  ? 90   GLN A CG    1 
ATOM   3905  C  CD    . GLN C 2 90  ? 52.724  98.682  51.365  1.00 70.68  ? 90   GLN A CD    1 
ATOM   3906  O  OE1   . GLN C 2 90  ? 52.745  98.731  52.597  1.00 70.65  ? 90   GLN A OE1   1 
ATOM   3907  N  NE2   . GLN C 2 90  ? 52.590  99.772  50.598  1.00 63.43  ? 90   GLN A NE2   1 
ATOM   3908  N  N     . LYS C 2 91  ? 50.736  98.358  46.948  1.00 33.40  ? 91   LYS A N     1 
ATOM   3909  C  CA    . LYS C 2 91  ? 50.470  99.287  45.849  1.00 36.73  ? 91   LYS A CA    1 
ATOM   3910  C  C     . LYS C 2 91  ? 48.975  99.639  45.740  1.00 34.85  ? 91   LYS A C     1 
ATOM   3911  O  O     . LYS C 2 91  ? 48.618  100.816 45.696  1.00 31.57  ? 91   LYS A O     1 
ATOM   3912  C  CB    . LYS C 2 91  ? 51.001  98.677  44.541  1.00 42.97  ? 91   LYS A CB    1 
ATOM   3913  C  CG    . LYS C 2 91  ? 50.885  99.551  43.308  1.00 53.08  ? 91   LYS A CG    1 
ATOM   3914  C  CD    . LYS C 2 91  ? 49.857  99.007  42.299  1.00 59.69  ? 91   LYS A CD    1 
ATOM   3915  C  CE    . LYS C 2 91  ? 50.304  97.705  41.617  1.00 52.29  ? 91   LYS A CE    1 
ATOM   3916  N  NZ    . LYS C 2 91  ? 51.196  97.937  40.457  1.00 50.44  ? 91   LYS A NZ    1 
ATOM   3917  N  N     . TYR C 2 92  ? 48.102  98.628  45.737  1.00 24.30  ? 92   TYR A N     1 
ATOM   3918  C  CA    . TYR C 2 92  ? 46.679  98.895  45.622  1.00 29.62  ? 92   TYR A CA    1 
ATOM   3919  C  C     . TYR C 2 92  ? 46.106  99.644  46.840  1.00 33.82  ? 92   TYR A C     1 
ATOM   3920  O  O     . TYR C 2 92  ? 45.224  100.490 46.676  1.00 31.02  ? 92   TYR A O     1 
ATOM   3921  C  CB    . TYR C 2 92  ? 45.901  97.597  45.327  1.00 26.92  ? 92   TYR A CB    1 
ATOM   3922  C  CG    . TYR C 2 92  ? 46.027  97.142  43.872  1.00 28.60  ? 92   TYR A CG    1 
ATOM   3923  C  CD1   . TYR C 2 92  ? 46.852  96.069  43.513  1.00 32.96  ? 92   TYR A CD1   1 
ATOM   3924  C  CD2   . TYR C 2 92  ? 45.346  97.805  42.858  1.00 25.37  ? 92   TYR A CD2   1 
ATOM   3925  C  CE1   . TYR C 2 92  ? 46.994  95.668  42.171  1.00 28.80  ? 92   TYR A CE1   1 
ATOM   3926  C  CE2   . TYR C 2 92  ? 45.476  97.425  41.525  1.00 34.55  ? 92   TYR A CE2   1 
ATOM   3927  C  CZ    . TYR C 2 92  ? 46.303  96.355  41.184  1.00 39.56  ? 92   TYR A CZ    1 
ATOM   3928  O  OH    . TYR C 2 92  ? 46.457  95.995  39.858  1.00 32.97  ? 92   TYR A OH    1 
ATOM   3929  N  N     . ALA C 2 93  ? 46.614  99.374  48.046  1.00 25.71  ? 93   ALA A N     1 
ATOM   3930  C  CA    . ALA C 2 93  ? 46.118  100.085 49.221  1.00 22.36  ? 93   ALA A CA    1 
ATOM   3931  C  C     . ALA C 2 93  ? 46.418  101.579 49.045  1.00 30.03  ? 93   ALA A C     1 
ATOM   3932  O  O     . ALA C 2 93  ? 45.575  102.437 49.316  1.00 23.74  ? 93   ALA A O     1 
ATOM   3933  C  CB    . ALA C 2 93  ? 46.773  99.563  50.477  1.00 16.00  ? 93   ALA A CB    1 
ATOM   3934  N  N     . GLU C 2 94  ? 47.624  101.883 48.583  1.00 29.69  ? 94   GLU A N     1 
ATOM   3935  C  CA    . GLU C 2 94  ? 48.014  103.266 48.349  1.00 34.10  ? 94   GLU A CA    1 
ATOM   3936  C  C     . GLU C 2 94  ? 47.172  103.907 47.234  1.00 32.48  ? 94   GLU A C     1 
ATOM   3937  O  O     . GLU C 2 94  ? 46.890  105.097 47.279  1.00 36.64  ? 94   GLU A O     1 
ATOM   3938  C  CB    . GLU C 2 94  ? 49.515  103.341 48.000  1.00 31.38  ? 94   GLU A CB    1 
ATOM   3939  C  CG    . GLU C 2 94  ? 50.420  103.031 49.190  1.00 36.03  ? 94   GLU A CG    1 
ATOM   3940  C  CD    . GLU C 2 94  ? 51.865  102.836 48.790  1.00 58.95  ? 94   GLU A CD    1 
ATOM   3941  O  OE1   . GLU C 2 94  ? 52.212  103.196 47.637  1.00 68.77  ? 94   GLU A OE1   1 
ATOM   3942  O  OE2   . GLU C 2 94  ? 52.653  102.335 49.630  1.00 57.59  ? 94   GLU A OE2   1 
ATOM   3943  N  N     . GLU C 2 95  ? 46.785  103.135 46.228  1.00 31.61  ? 95   GLU A N     1 
ATOM   3944  C  CA    . GLU C 2 95  ? 45.954  103.692 45.159  1.00 30.04  ? 95   GLU A CA    1 
ATOM   3945  C  C     . GLU C 2 95  ? 44.571  104.038 45.732  1.00 29.90  ? 95   GLU A C     1 
ATOM   3946  O  O     . GLU C 2 95  ? 43.937  104.997 45.315  1.00 23.24  ? 95   GLU A O     1 
ATOM   3947  C  CB    . GLU C 2 95  ? 45.818  102.684 44.011  1.00 33.74  ? 95   GLU A CB    1 
ATOM   3948  C  CG    . GLU C 2 95  ? 45.036  103.186 42.789  1.00 51.77  ? 95   GLU A CG    1 
ATOM   3949  C  CD    . GLU C 2 95  ? 45.547  104.525 42.221  1.00 61.76  ? 95   GLU A CD    1 
ATOM   3950  O  OE1   . GLU C 2 95  ? 46.769  104.817 42.278  1.00 58.93  ? 95   GLU A OE1   1 
ATOM   3951  O  OE2   . GLU C 2 95  ? 44.705  105.285 41.696  1.00 66.30  ? 95   GLU A OE2   1 
ATOM   3952  N  N     . LEU C 2 96  ? 44.099  103.263 46.705  1.00 30.28  ? 96   LEU A N     1 
ATOM   3953  C  CA    . LEU C 2 96  ? 42.799  103.566 47.299  1.00 31.54  ? 96   LEU A CA    1 
ATOM   3954  C  C     . LEU C 2 96  ? 42.943  104.883 48.066  1.00 37.03  ? 96   LEU A C     1 
ATOM   3955  O  O     . LEU C 2 96  ? 42.028  105.714 48.055  1.00 35.48  ? 96   LEU A O     1 
ATOM   3956  C  CB    . LEU C 2 96  ? 42.356  102.436 48.232  1.00 21.99  ? 96   LEU A CB    1 
ATOM   3957  C  CG    . LEU C 2 96  ? 41.144  101.594 47.783  1.00 37.47  ? 96   LEU A CG    1 
ATOM   3958  C  CD1   . LEU C 2 96  ? 41.182  101.351 46.301  1.00 30.93  ? 96   LEU A CD1   1 
ATOM   3959  C  CD2   . LEU C 2 96  ? 41.102  100.281 48.545  1.00 34.60  ? 96   LEU A CD2   1 
ATOM   3960  N  N     . LEU C 2 97  ? 44.106  105.068 48.708  1.00 35.18  ? 97   LEU A N     1 
ATOM   3961  C  CA    . LEU C 2 97  ? 44.426  106.275 49.489  1.00 31.58  ? 97   LEU A CA    1 
ATOM   3962  C  C     . LEU C 2 97  ? 44.277  107.523 48.624  1.00 35.99  ? 97   LEU A C     1 
ATOM   3963  O  O     . LEU C 2 97  ? 43.614  108.494 49.005  1.00 32.73  ? 97   LEU A O     1 
ATOM   3964  C  CB    . LEU C 2 97  ? 45.860  106.191 50.009  1.00 36.80  ? 97   LEU A CB    1 
ATOM   3965  C  CG    . LEU C 2 97  ? 46.143  105.994 51.501  1.00 35.22  ? 97   LEU A CG    1 
ATOM   3966  C  CD1   . LEU C 2 97  ? 45.104  105.110 52.102  1.00 36.12  ? 97   LEU A CD1   1 
ATOM   3967  C  CD2   . LEU C 2 97  ? 47.544  105.402 51.699  1.00 30.34  ? 97   LEU A CD2   1 
ATOM   3968  N  N     . LYS C 2 98  ? 44.897  107.475 47.453  1.00 33.17  ? 98   LYS A N     1 
ATOM   3969  C  CA    . LYS C 2 98  ? 44.841  108.564 46.505  1.00 38.95  ? 98   LYS A CA    1 
ATOM   3970  C  C     . LYS C 2 98  ? 43.417  108.785 45.984  1.00 43.82  ? 98   LYS A C     1 
ATOM   3971  O  O     . LYS C 2 98  ? 42.955  109.933 45.904  1.00 48.81  ? 98   LYS A O     1 
ATOM   3972  C  CB    . LYS C 2 98  ? 45.814  108.294 45.355  1.00 35.60  ? 98   LYS A CB    1 
ATOM   3973  C  CG    . LYS C 2 98  ? 47.232  108.747 45.683  1.00 58.30  ? 98   LYS A CG    1 
ATOM   3974  C  CD    . LYS C 2 98  ? 48.324  107.751 45.243  1.00 71.60  ? 98   LYS A CD    1 
ATOM   3975  C  CE    . LYS C 2 98  ? 48.436  107.620 43.724  1.00 73.29  ? 98   LYS A CE    1 
ATOM   3976  N  NZ    . LYS C 2 98  ? 49.281  106.444 43.341  1.00 73.16  ? 98   LYS A NZ    1 
ATOM   3977  N  N     . ARG C 2 99  ? 42.708  107.707 45.660  1.00 41.68  ? 99   ARG A N     1 
ATOM   3978  C  CA    . ARG C 2 99  ? 41.341  107.833 45.148  1.00 39.70  ? 99   ARG A CA    1 
ATOM   3979  C  C     . ARG C 2 99  ? 40.374  108.353 46.199  1.00 39.37  ? 99   ARG A C     1 
ATOM   3980  O  O     . ARG C 2 99  ? 39.218  108.646 45.904  1.00 38.42  ? 99   ARG A O     1 
ATOM   3981  C  CB    . ARG C 2 99  ? 40.839  106.487 44.630  1.00 43.92  ? 99   ARG A CB    1 
ATOM   3982  C  CG    . ARG C 2 99  ? 41.511  106.044 43.353  1.00 51.93  ? 99   ARG A CG    1 
ATOM   3983  C  CD    . ARG C 2 99  ? 41.150  104.604 43.014  1.00 62.71  ? 99   ARG A CD    1 
ATOM   3984  N  NE    . ARG C 2 99  ? 41.824  104.182 41.792  1.00 67.66  ? 99   ARG A NE    1 
ATOM   3985  C  CZ    . ARG C 2 99  ? 41.404  104.479 40.568  1.00 75.07  ? 99   ARG A CZ    1 
ATOM   3986  N  NH1   . ARG C 2 99  ? 40.293  105.188 40.396  1.00 75.59  ? 99   ARG A NH1   1 
ATOM   3987  N  NH2   . ARG C 2 99  ? 42.123  104.103 39.514  1.00 80.52  ? 99   ARG A NH2   1 
ATOM   3988  N  N     . GLY C 2 100 ? 40.848  108.470 47.429  1.00 37.44  ? 100  GLY A N     1 
ATOM   3989  C  CA    . GLY C 2 100 ? 39.977  108.926 48.487  1.00 40.05  ? 100  GLY A CA    1 
ATOM   3990  C  C     . GLY C 2 100 ? 39.071  107.824 49.021  1.00 42.21  ? 100  GLY A C     1 
ATOM   3991  O  O     . GLY C 2 100 ? 38.056  108.127 49.641  1.00 46.53  ? 100  GLY A O     1 
ATOM   3992  N  N     . TRP C 2 101 ? 39.435  106.556 48.811  1.00 32.25  ? 101  TRP A N     1 
ATOM   3993  C  CA    . TRP C 2 101 ? 38.621  105.435 49.281  1.00 32.73  ? 101  TRP A CA    1 
ATOM   3994  C  C     . TRP C 2 101 ? 39.137  104.688 50.499  1.00 26.56  ? 101  TRP A C     1 
ATOM   3995  O  O     . TRP C 2 101 ? 38.559  103.685 50.896  1.00 28.46  ? 101  TRP A O     1 
ATOM   3996  C  CB    . TRP C 2 101 ? 38.411  104.424 48.165  1.00 35.42  ? 101  TRP A CB    1 
ATOM   3997  C  CG    . TRP C 2 101 ? 37.233  104.699 47.280  1.00 41.02  ? 101  TRP A CG    1 
ATOM   3998  C  CD1   . TRP C 2 101 ? 37.238  105.375 46.091  1.00 39.37  ? 101  TRP A CD1   1 
ATOM   3999  C  CD2   . TRP C 2 101 ? 35.906  104.174 47.438  1.00 38.66  ? 101  TRP A CD2   1 
ATOM   4000  N  NE1   . TRP C 2 101 ? 35.998  105.287 45.486  1.00 44.22  ? 101  TRP A NE1   1 
ATOM   4001  C  CE2   . TRP C 2 101 ? 35.164  104.554 46.288  1.00 42.77  ? 101  TRP A CE2   1 
ATOM   4002  C  CE3   . TRP C 2 101 ? 35.276  103.417 48.429  1.00 31.39  ? 101  TRP A CE3   1 
ATOM   4003  C  CZ2   . TRP C 2 101 ? 33.827  104.192 46.103  1.00 38.80  ? 101  TRP A CZ2   1 
ATOM   4004  C  CZ3   . TRP C 2 101 ? 33.936  103.056 48.246  1.00 34.49  ? 101  TRP A CZ3   1 
ATOM   4005  C  CH2   . TRP C 2 101 ? 33.230  103.446 47.089  1.00 36.95  ? 101  TRP A CH2   1 
ATOM   4006  N  N     . ALA C 2 102 ? 40.210  105.189 51.096  1.00 29.56  ? 102  ALA A N     1 
ATOM   4007  C  CA    . ALA C 2 102 ? 40.821  104.570 52.268  1.00 28.82  ? 102  ALA A CA    1 
ATOM   4008  C  C     . ALA C 2 102 ? 41.537  105.652 53.038  1.00 31.57  ? 102  ALA A C     1 
ATOM   4009  O  O     . ALA C 2 102 ? 41.739  106.741 52.535  1.00 34.75  ? 102  ALA A O     1 
ATOM   4010  C  CB    . ALA C 2 102 ? 41.833  103.512 51.842  1.00 28.78  ? 102  ALA A CB    1 
ATOM   4011  N  N     . TYR C 2 103 ? 41.944  105.354 54.256  1.00 22.66  ? 103  TYR A N     1 
ATOM   4012  C  CA    . TYR C 2 103 ? 42.652  106.346 55.037  1.00 30.26  ? 103  TYR A CA    1 
ATOM   4013  C  C     . TYR C 2 103 ? 43.544  105.638 56.013  1.00 23.65  ? 103  TYR A C     1 
ATOM   4014  O  O     . TYR C 2 103 ? 43.300  104.487 56.354  1.00 27.00  ? 103  TYR A O     1 
ATOM   4015  C  CB    . TYR C 2 103 ? 41.675  107.224 55.794  1.00 21.44  ? 103  TYR A CB    1 
ATOM   4016  C  CG    . TYR C 2 103 ? 40.760  106.452 56.735  1.00 28.81  ? 103  TYR A CG    1 
ATOM   4017  C  CD1   . TYR C 2 103 ? 41.036  106.375 58.102  1.00 17.74  ? 103  TYR A CD1   1 
ATOM   4018  C  CD2   . TYR C 2 103 ? 39.578  105.870 56.268  1.00 22.88  ? 103  TYR A CD2   1 
ATOM   4019  C  CE1   . TYR C 2 103 ? 40.156  105.750 58.977  1.00 24.03  ? 103  TYR A CE1   1 
ATOM   4020  C  CE2   . TYR C 2 103 ? 38.688  105.240 57.139  1.00 25.77  ? 103  TYR A CE2   1 
ATOM   4021  C  CZ    . TYR C 2 103 ? 38.980  105.184 58.484  1.00 26.35  ? 103  TYR A CZ    1 
ATOM   4022  O  OH    . TYR C 2 103 ? 38.115  104.552 59.343  1.00 28.62  ? 103  TYR A OH    1 
ATOM   4023  N  N     . ARG C 2 104 ? 44.589  106.322 56.440  1.00 25.80  ? 104  ARG A N     1 
ATOM   4024  C  CA    . ARG C 2 104 ? 45.523  105.760 57.397  1.00 25.98  ? 104  ARG A CA    1 
ATOM   4025  C  C     . ARG C 2 104 ? 44.967  105.963 58.799  1.00 25.57  ? 104  ARG A C     1 
ATOM   4026  O  O     . ARG C 2 104 ? 44.347  106.990 59.092  1.00 28.20  ? 104  ARG A O     1 
ATOM   4027  C  CB    . ARG C 2 104 ? 46.888  106.438 57.256  1.00 31.27  ? 104  ARG A CB    1 
ATOM   4028  C  CG    . ARG C 2 104 ? 47.582  106.211 55.904  1.00 29.86  ? 104  ARG A CG    1 
ATOM   4029  C  CD    . ARG C 2 104 ? 49.025  106.708 55.937  1.00 25.81  ? 104  ARG A CD    1 
ATOM   4030  N  NE    . ARG C 2 104 ? 49.564  107.035 54.618  1.00 33.69  ? 104  ARG A NE    1 
ATOM   4031  C  CZ    . ARG C 2 104 ? 50.217  106.163 53.852  1.00 41.82  ? 104  ARG A CZ    1 
ATOM   4032  N  NH1   . ARG C 2 104 ? 50.684  106.527 52.671  1.00 32.24  ? 104  ARG A NH1   1 
ATOM   4033  N  NH2   . ARG C 2 104 ? 50.412  104.923 54.275  1.00 34.54  ? 104  ARG A NH2   1 
ATOM   4034  N  N     . ALA C 2 105 ? 45.183  104.980 59.659  1.00 21.10  ? 105  ALA A N     1 
ATOM   4035  C  CA    . ALA C 2 105 ? 44.698  105.026 61.034  1.00 28.05  ? 105  ALA A CA    1 
ATOM   4036  C  C     . ALA C 2 105 ? 45.840  104.531 61.943  1.00 33.26  ? 105  ALA A C     1 
ATOM   4037  O  O     . ALA C 2 105 ? 46.395  103.449 61.718  1.00 28.99  ? 105  ALA A O     1 
ATOM   4038  C  CB    . ALA C 2 105 ? 43.437  104.130 61.172  1.00 23.08  ? 105  ALA A CB    1 
ATOM   4039  N  N     . PHE C 2 106 ? 46.164  105.300 62.979  1.00 29.70  ? 106  PHE A N     1 
ATOM   4040  C  CA    . PHE C 2 106 ? 47.280  104.962 63.843  1.00 28.02  ? 106  PHE A CA    1 
ATOM   4041  C  C     . PHE C 2 106 ? 46.991  104.442 65.224  1.00 28.88  ? 106  PHE A C     1 
ATOM   4042  O  O     . PHE C 2 106 ? 47.907  104.321 66.028  1.00 33.83  ? 106  PHE A O     1 
ATOM   4043  C  CB    . PHE C 2 106 ? 48.188  106.179 63.985  1.00 27.88  ? 106  PHE A CB    1 
ATOM   4044  C  CG    . PHE C 2 106 ? 48.553  106.805 62.690  1.00 18.04  ? 106  PHE A CG    1 
ATOM   4045  C  CD1   . PHE C 2 106 ? 47.621  107.530 61.968  1.00 29.01  ? 106  PHE A CD1   1 
ATOM   4046  C  CD2   . PHE C 2 106 ? 49.827  106.659 62.180  1.00 24.69  ? 106  PHE A CD2   1 
ATOM   4047  C  CE1   . PHE C 2 106 ? 47.957  108.112 60.742  1.00 28.55  ? 106  PHE A CE1   1 
ATOM   4048  C  CE2   . PHE C 2 106 ? 50.186  107.236 60.951  1.00 25.46  ? 106  PHE A CE2   1 
ATOM   4049  C  CZ    . PHE C 2 106 ? 49.247  107.961 60.236  1.00 27.79  ? 106  PHE A CZ    1 
ATOM   4050  N  N     . GLU C 2 107 ? 45.745  104.132 65.529  1.00 27.41  ? 107  GLU A N     1 
ATOM   4051  C  CA    . GLU C 2 107 ? 45.454  103.644 66.880  1.00 28.44  ? 107  GLU A CA    1 
ATOM   4052  C  C     . GLU C 2 107 ? 46.183  102.331 67.200  1.00 35.89  ? 107  GLU A C     1 
ATOM   4053  O  O     . GLU C 2 107 ? 46.322  101.447 66.339  1.00 31.01  ? 107  GLU A O     1 
ATOM   4054  C  CB    . GLU C 2 107 ? 43.942  103.397 67.090  1.00 22.62  ? 107  GLU A CB    1 
ATOM   4055  C  CG    . GLU C 2 107 ? 42.988  104.597 66.884  1.00 23.45  ? 107  GLU A CG    1 
ATOM   4056  C  CD    . GLU C 2 107 ? 42.723  104.878 65.423  1.00 32.05  ? 107  GLU A CD    1 
ATOM   4057  O  OE1   . GLU C 2 107 ? 42.026  105.870 65.135  1.00 41.79  ? 107  GLU A OE1   1 
ATOM   4058  O  OE2   . GLU C 2 107 ? 43.219  104.117 64.555  1.00 33.68  ? 107  GLU A OE2   1 
ATOM   4059  N  N     . THR C 2 108 ? 46.623  102.206 68.450  1.00 32.07  ? 108  THR A N     1 
ATOM   4060  C  CA    . THR C 2 108 ? 47.263  100.991 68.944  1.00 31.52  ? 108  THR A CA    1 
ATOM   4061  C  C     . THR C 2 108 ? 46.152  99.949  69.118  1.00 35.90  ? 108  THR A C     1 
ATOM   4062  O  O     . THR C 2 108 ? 44.967  100.303 69.243  1.00 38.20  ? 108  THR A O     1 
ATOM   4063  C  CB    . THR C 2 108 ? 47.846  101.189 70.348  1.00 29.64  ? 108  THR A CB    1 
ATOM   4064  O  OG1   . THR C 2 108 ? 46.785  101.603 71.228  1.00 32.08  ? 108  THR A OG1   1 
ATOM   4065  C  CG2   . THR C 2 108 ? 48.945  102.222 70.338  1.00 23.27  ? 108  THR A CG2   1 
ATOM   4066  N  N     . PRO C 2 109 ? 46.509  98.656  69.150  1.00 31.13  ? 109  PRO A N     1 
ATOM   4067  C  CA    . PRO C 2 109 ? 45.450  97.655  69.327  1.00 28.85  ? 109  PRO A CA    1 
ATOM   4068  C  C     . PRO C 2 109 ? 44.711  97.925  70.639  1.00 34.48  ? 109  PRO A C     1 
ATOM   4069  O  O     . PRO C 2 109 ? 43.510  97.677  70.750  1.00 40.91  ? 109  PRO A O     1 
ATOM   4070  C  CB    . PRO C 2 109 ? 46.216  96.319  69.356  1.00 24.73  ? 109  PRO A CB    1 
ATOM   4071  C  CG    . PRO C 2 109 ? 47.382  96.583  68.488  1.00 29.70  ? 109  PRO A CG    1 
ATOM   4072  C  CD    . PRO C 2 109 ? 47.802  98.015  68.848  1.00 33.88  ? 109  PRO A CD    1 
ATOM   4073  N  N     . GLU C 2 110 ? 45.426  98.445  71.638  1.00 42.61  ? 110  GLU A N     1 
ATOM   4074  C  CA    . GLU C 2 110 ? 44.798  98.730  72.930  1.00 34.21  ? 110  GLU A CA    1 
ATOM   4075  C  C     . GLU C 2 110 ? 43.737  99.813  72.828  1.00 35.16  ? 110  GLU A C     1 
ATOM   4076  O  O     . GLU C 2 110 ? 42.649  99.655  73.379  1.00 34.62  ? 110  GLU A O     1 
ATOM   4077  C  CB    . GLU C 2 110 ? 45.847  99.119  73.981  1.00 43.83  ? 110  GLU A CB    1 
ATOM   4078  C  CG    . GLU C 2 110 ? 46.806  98.002  74.357  1.00 41.35  ? 110  GLU A CG    1 
ATOM   4079  C  CD    . GLU C 2 110 ? 47.841  97.747  73.268  1.00 52.97  ? 110  GLU A CD    1 
ATOM   4080  O  OE1   . GLU C 2 110 ? 48.344  96.608  73.163  1.00 57.11  ? 110  GLU A OE1   1 
ATOM   4081  O  OE2   . GLU C 2 110 ? 48.157  98.691  72.519  1.00 54.64  ? 110  GLU A OE2   1 
ATOM   4082  N  N     . GLU C 2 111 ? 44.040  100.912 72.136  1.00 34.18  ? 111  GLU A N     1 
ATOM   4083  C  CA    . GLU C 2 111 ? 43.050  101.969 71.997  1.00 30.58  ? 111  GLU A CA    1 
ATOM   4084  C  C     . GLU C 2 111 ? 41.824  101.401 71.295  1.00 34.96  ? 111  GLU A C     1 
ATOM   4085  O  O     . GLU C 2 111 ? 40.696  101.654 71.708  1.00 32.88  ? 111  GLU A O     1 
ATOM   4086  C  CB    . GLU C 2 111 ? 43.575  103.165 71.181  1.00 32.64  ? 111  GLU A CB    1 
ATOM   4087  C  CG    . GLU C 2 111 ? 42.568  104.343 71.191  1.00 34.55  ? 111  GLU A CG    1 
ATOM   4088  C  CD    . GLU C 2 111 ? 42.975  105.542 70.343  1.00 33.60  ? 111  GLU A CD    1 
ATOM   4089  O  OE1   . GLU C 2 111 ? 44.178  105.702 70.054  1.00 42.06  ? 111  GLU A OE1   1 
ATOM   4090  O  OE2   . GLU C 2 111 ? 42.086  106.350 69.982  1.00 38.94  ? 111  GLU A OE2   1 
ATOM   4091  N  N     . LEU C 2 112 ? 42.043  100.628 70.230  1.00 36.00  ? 112  LEU A N     1 
ATOM   4092  C  CA    . LEU C 2 112 ? 40.920  100.045 69.490  1.00 34.99  ? 112  LEU A CA    1 
ATOM   4093  C  C     . LEU C 2 112 ? 39.978  99.252  70.377  1.00 31.51  ? 112  LEU A C     1 
ATOM   4094  O  O     . LEU C 2 112 ? 38.762  99.348  70.239  1.00 36.14  ? 112  LEU A O     1 
ATOM   4095  C  CB    . LEU C 2 112 ? 41.414  99.128  68.366  1.00 26.84  ? 112  LEU A CB    1 
ATOM   4096  C  CG    . LEU C 2 112 ? 42.104  99.857  67.224  1.00 34.16  ? 112  LEU A CG    1 
ATOM   4097  C  CD1   . LEU C 2 112 ? 42.711  98.857  66.219  1.00 38.70  ? 112  LEU A CD1   1 
ATOM   4098  C  CD2   . LEU C 2 112 ? 41.082  100.756 66.551  1.00 23.75  ? 112  LEU A CD2   1 
ATOM   4099  N  N     . GLU C 2 113 ? 40.548  98.457  71.272  1.00 35.34  ? 113  GLU A N     1 
ATOM   4100  C  CA    . GLU C 2 113 ? 39.756  97.632  72.170  1.00 37.32  ? 113  GLU A CA    1 
ATOM   4101  C  C     . GLU C 2 113 ? 38.889  98.527  73.012  1.00 41.56  ? 113  GLU A C     1 
ATOM   4102  O  O     . GLU C 2 113 ? 37.698  98.271  73.214  1.00 39.16  ? 113  GLU A O     1 
ATOM   4103  C  CB    . GLU C 2 113 ? 40.674  96.822  73.076  1.00 47.84  ? 113  GLU A CB    1 
ATOM   4104  C  CG    . GLU C 2 113 ? 39.946  96.010  74.132  1.00 60.87  ? 113  GLU A CG    1 
ATOM   4105  C  CD    . GLU C 2 113 ? 40.898  95.399  75.146  1.00 70.49  ? 113  GLU A CD    1 
ATOM   4106  O  OE1   . GLU C 2 113 ? 40.433  94.559  75.950  1.00 76.05  ? 113  GLU A OE1   1 
ATOM   4107  O  OE2   . GLU C 2 113 ? 42.104  95.761  75.143  1.00 70.65  ? 113  GLU A OE2   1 
ATOM   4108  N  N     . GLN C 2 114 ? 39.500  99.600  73.501  1.00 45.07  ? 114  GLN A N     1 
ATOM   4109  C  CA    . GLN C 2 114 ? 38.791  100.556 74.335  1.00 38.36  ? 114  GLN A CA    1 
ATOM   4110  C  C     . GLN C 2 114 ? 37.665  101.208 73.509  1.00 32.80  ? 114  GLN A C     1 
ATOM   4111  O  O     . GLN C 2 114 ? 36.541  101.331 73.985  1.00 38.30  ? 114  GLN A O     1 
ATOM   4112  C  CB    . GLN C 2 114 ? 39.798  101.581 74.865  1.00 43.08  ? 114  GLN A CB    1 
ATOM   4113  C  CG    . GLN C 2 114 ? 39.535  102.123 76.272  1.00 60.05  ? 114  GLN A CG    1 
ATOM   4114  C  CD    . GLN C 2 114 ? 39.275  101.045 77.319  1.00 63.53  ? 114  GLN A CD    1 
ATOM   4115  O  OE1   . GLN C 2 114 ? 40.003  100.053 77.418  1.00 61.34  ? 114  GLN A OE1   1 
ATOM   4116  N  NE2   . GLN C 2 114 ? 38.234  101.250 78.122  1.00 64.36  ? 114  GLN A NE2   1 
ATOM   4117  N  N     . ILE C 2 115 ? 37.958  101.592 72.267  1.00 25.71  ? 115  ILE A N     1 
ATOM   4118  C  CA    . ILE C 2 115 ? 36.964  102.208 71.393  1.00 28.01  ? 115  ILE A CA    1 
ATOM   4119  C  C     . ILE C 2 115 ? 35.813  101.233 71.193  1.00 32.10  ? 115  ILE A C     1 
ATOM   4120  O  O     . ILE C 2 115 ? 34.638  101.603 71.207  1.00 30.02  ? 115  ILE A O     1 
ATOM   4121  C  CB    . ILE C 2 115 ? 37.561  102.523 69.999  1.00 25.12  ? 115  ILE A CB    1 
ATOM   4122  C  CG1   . ILE C 2 115 ? 38.612  103.616 70.122  1.00 24.62  ? 115  ILE A CG1   1 
ATOM   4123  C  CG2   . ILE C 2 115 ? 36.471  102.973 69.035  1.00 23.66  ? 115  ILE A CG2   1 
ATOM   4124  C  CD1   . ILE C 2 115 ? 39.340  103.878 68.839  1.00 31.69  ? 115  ILE A CD1   1 
ATOM   4125  N  N     . ARG C 2 116 ? 36.171  99.975  70.986  1.00 34.31  ? 116  ARG A N     1 
ATOM   4126  C  CA    . ARG C 2 116 ? 35.190  98.920  70.763  1.00 36.98  ? 116  ARG A CA    1 
ATOM   4127  C  C     . ARG C 2 116 ? 34.304  98.736  72.017  1.00 45.13  ? 116  ARG A C     1 
ATOM   4128  O  O     . ARG C 2 116 ? 33.087  98.537  71.922  1.00 34.63  ? 116  ARG A O     1 
ATOM   4129  C  CB    . ARG C 2 116 ? 35.953  97.644  70.424  1.00 37.25  ? 116  ARG A CB    1 
ATOM   4130  C  CG    . ARG C 2 116 ? 35.258  96.706  69.502  1.00 46.87  ? 116  ARG A CG    1 
ATOM   4131  C  CD    . ARG C 2 116 ? 36.256  96.009  68.591  1.00 40.35  ? 116  ARG A CD    1 
ATOM   4132  N  NE    . ARG C 2 116 ? 37.406  95.504  69.327  1.00 49.39  ? 116  ARG A NE    1 
ATOM   4133  C  CZ    . ARG C 2 116 ? 38.628  95.426  68.805  1.00 56.40  ? 116  ARG A CZ    1 
ATOM   4134  N  NH1   . ARG C 2 116 ? 38.836  95.813  67.539  1.00 46.16  ? 116  ARG A NH1   1 
ATOM   4135  N  NH2   . ARG C 2 116 ? 39.646  95.016  69.560  1.00 38.37  ? 116  ARG A NH2   1 
ATOM   4136  N  N     . LYS C 2 117 ? 34.919  98.818  73.193  1.00 47.38  ? 117  LYS A N     1 
ATOM   4137  C  CA    . LYS C 2 117 ? 34.182  98.678  74.439  1.00 53.53  ? 117  LYS A CA    1 
ATOM   4138  C  C     . LYS C 2 117 ? 33.207  99.834  74.660  1.00 61.39  ? 117  LYS A C     1 
ATOM   4139  O  O     . LYS C 2 117 ? 32.130  99.645  75.225  1.00 63.38  ? 117  LYS A O     1 
ATOM   4140  C  CB    . LYS C 2 117 ? 35.141  98.610  75.628  1.00 59.37  ? 117  LYS A CB    1 
ATOM   4141  C  CG    . LYS C 2 117 ? 34.425  98.783  76.961  1.00 63.63  ? 117  LYS A CG    1 
ATOM   4142  C  CD    . LYS C 2 117 ? 35.358  99.175  78.094  1.00 57.98  ? 117  LYS A CD    1 
ATOM   4143  C  CE    . LYS C 2 117 ? 36.318  98.063  78.454  1.00 65.62  ? 117  LYS A CE    1 
ATOM   4144  N  NZ    . LYS C 2 117 ? 37.157  98.435  79.632  1.00 67.22  ? 117  LYS A NZ    1 
ATOM   4145  N  N     . GLU C 2 118 ? 33.575  101.028 74.208  1.00 60.96  ? 118  GLU A N     1 
ATOM   4146  C  CA    . GLU C 2 118 ? 32.719  102.189 74.400  1.00 62.75  ? 118  GLU A CA    1 
ATOM   4147  C  C     . GLU C 2 118 ? 31.660  102.387 73.330  1.00 64.50  ? 118  GLU A C     1 
ATOM   4148  O  O     . GLU C 2 118 ? 30.586  102.905 73.618  1.00 57.16  ? 118  GLU A O     1 
ATOM   4149  C  CB    . GLU C 2 118 ? 33.575  103.448 74.495  1.00 75.82  ? 118  GLU A CB    1 
ATOM   4150  C  CG    . GLU C 2 118 ? 34.638  103.391 75.588  1.00 85.32  ? 118  GLU A CG    1 
ATOM   4151  C  CD    . GLU C 2 118 ? 34.051  103.401 76.988  1.00 89.70  ? 118  GLU A CD    1 
ATOM   4152  O  OE1   . GLU C 2 118 ? 33.389  104.400 77.356  1.00 84.99  ? 118  GLU A OE1   1 
ATOM   4153  O  OE2   . GLU C 2 118 ? 34.258  102.406 77.719  1.00 93.01  ? 118  GLU A OE2   1 
ATOM   4154  N  N     . LYS C 2 119 ? 31.955  101.978 72.099  1.00 65.51  ? 119  LYS A N     1 
ATOM   4155  C  CA    . LYS C 2 119 ? 31.010  102.153 71.003  1.00 62.18  ? 119  LYS A CA    1 
ATOM   4156  C  C     . LYS C 2 119 ? 30.753  100.880 70.200  1.00 65.56  ? 119  LYS A C     1 
ATOM   4157  O  O     . LYS C 2 119 ? 30.038  100.912 69.195  1.00 66.74  ? 119  LYS A O     1 
ATOM   4158  C  CB    . LYS C 2 119 ? 31.517  103.253 70.072  1.00 66.66  ? 119  LYS A CB    1 
ATOM   4159  C  CG    . LYS C 2 119 ? 31.963  104.511 70.803  1.00 68.98  ? 119  LYS A CG    1 
ATOM   4160  C  CD    . LYS C 2 119 ? 32.219  105.625 69.824  1.00 69.78  ? 119  LYS A CD    1 
ATOM   4161  C  CE    . LYS C 2 119 ? 32.614  106.908 70.529  1.00 80.37  ? 119  LYS A CE    1 
ATOM   4162  N  NZ    . LYS C 2 119 ? 32.815  108.026 69.549  1.00 85.46  ? 119  LYS A NZ    1 
ATOM   4163  N  N     . GLY C 2 120 ? 31.339  99.768  70.633  1.00 61.78  ? 120  GLY A N     1 
ATOM   4164  C  CA    . GLY C 2 120 ? 31.142  98.509  69.935  1.00 64.08  ? 120  GLY A CA    1 
ATOM   4165  C  C     . GLY C 2 120 ? 31.575  98.462  68.475  1.00 65.14  ? 120  GLY A C     1 
ATOM   4166  O  O     . GLY C 2 120 ? 30.817  97.998  67.621  1.00 75.08  ? 120  GLY A O     1 
ATOM   4167  N  N     . GLY C 2 121 ? 32.788  98.923  68.179  1.00 58.78  ? 121  GLY A N     1 
ATOM   4168  C  CA    . GLY C 2 121 ? 33.275  98.894  66.810  1.00 46.43  ? 121  GLY A CA    1 
ATOM   4169  C  C     . GLY C 2 121 ? 34.041  100.167 66.564  1.00 48.02  ? 121  GLY A C     1 
ATOM   4170  O  O     . GLY C 2 121 ? 33.773  101.151 67.232  1.00 55.79  ? 121  GLY A O     1 
ATOM   4171  N  N     . TYR C 2 122 ? 34.977  100.178 65.621  1.00 44.56  ? 122  TYR A N     1 
ATOM   4172  C  CA    . TYR C 2 122 ? 35.737  101.401 65.353  1.00 37.81  ? 122  TYR A CA    1 
ATOM   4173  C  C     . TYR C 2 122 ? 34.793  102.495 64.844  1.00 34.40  ? 122  TYR A C     1 
ATOM   4174  O  O     . TYR C 2 122 ? 33.879  102.232 64.027  1.00 29.52  ? 122  TYR A O     1 
ATOM   4175  C  CB    . TYR C 2 122 ? 36.860  101.128 64.342  1.00 26.67  ? 122  TYR A CB    1 
ATOM   4176  C  CG    . TYR C 2 122 ? 37.789  102.310 64.073  1.00 33.79  ? 122  TYR A CG    1 
ATOM   4177  C  CD1   . TYR C 2 122 ? 38.501  102.929 65.112  1.00 37.72  ? 122  TYR A CD1   1 
ATOM   4178  C  CD2   . TYR C 2 122 ? 38.001  102.775 62.772  1.00 26.34  ? 122  TYR A CD2   1 
ATOM   4179  C  CE1   . TYR C 2 122 ? 39.404  103.967 64.856  1.00 27.49  ? 122  TYR A CE1   1 
ATOM   4180  C  CE2   . TYR C 2 122 ? 38.893  103.815 62.512  1.00 29.96  ? 122  TYR A CE2   1 
ATOM   4181  C  CZ    . TYR C 2 122 ? 39.593  104.402 63.554  1.00 29.64  ? 122  TYR A CZ    1 
ATOM   4182  O  OH    . TYR C 2 122 ? 40.497  105.407 63.279  1.00 37.18  ? 122  TYR A OH    1 
ATOM   4183  N  N     . ASP C 2 123 ? 35.015  103.720 65.320  1.00 25.69  ? 123  ASP A N     1 
ATOM   4184  C  CA    . ASP C 2 123 ? 34.154  104.847 64.938  1.00 33.56  ? 123  ASP A CA    1 
ATOM   4185  C  C     . ASP C 2 123 ? 34.682  105.714 63.798  1.00 33.55  ? 123  ASP A C     1 
ATOM   4186  O  O     . ASP C 2 123 ? 34.189  106.816 63.572  1.00 40.51  ? 123  ASP A O     1 
ATOM   4187  C  CB    . ASP C 2 123 ? 33.830  105.723 66.165  1.00 29.77  ? 123  ASP A CB    1 
ATOM   4188  C  CG    . ASP C 2 123 ? 35.070  106.242 66.863  1.00 38.71  ? 123  ASP A CG    1 
ATOM   4189  O  OD1   . ASP C 2 123 ? 36.171  106.160 66.258  1.00 35.67  ? 123  ASP A OD1   1 
ATOM   4190  O  OD2   . ASP C 2 123 ? 34.942  106.741 68.011  1.00 31.27  ? 123  ASP A OD2   1 
ATOM   4191  N  N     . GLY C 2 124 ? 35.673  105.203 63.078  1.00 24.00  ? 124  GLY A N     1 
ATOM   4192  C  CA    . GLY C 2 124 ? 36.237  105.934 61.961  1.00 22.55  ? 124  GLY A CA    1 
ATOM   4193  C  C     . GLY C 2 124 ? 36.873  107.251 62.332  1.00 28.26  ? 124  GLY A C     1 
ATOM   4194  O  O     . GLY C 2 124 ? 36.989  108.124 61.475  1.00 25.31  ? 124  GLY A O     1 
ATOM   4195  N  N     . ARG C 2 125 ? 37.302  107.391 63.591  1.00 28.20  ? 125  ARG A N     1 
ATOM   4196  C  CA    . ARG C 2 125 ? 37.906  108.635 64.062  1.00 29.71  ? 125  ARG A CA    1 
ATOM   4197  C  C     . ARG C 2 125 ? 39.102  109.124 63.248  1.00 25.47  ? 125  ARG A C     1 
ATOM   4198  O  O     . ARG C 2 125 ? 39.318  110.329 63.140  1.00 24.36  ? 125  ARG A O     1 
ATOM   4199  C  CB    . ARG C 2 125 ? 38.302  108.523 65.542  1.00 21.20  ? 125  ARG A CB    1 
ATOM   4200  C  CG    . ARG C 2 125 ? 39.360  107.463 65.846  1.00 24.58  ? 125  ARG A CG    1 
ATOM   4201  C  CD    . ARG C 2 125 ? 39.529  107.314 67.370  1.00 29.04  ? 125  ARG A CD    1 
ATOM   4202  N  NE    . ARG C 2 125 ? 38.218  107.200 68.020  1.00 23.32  ? 125  ARG A NE    1 
ATOM   4203  C  CZ    . ARG C 2 125 ? 38.012  107.164 69.337  1.00 35.20  ? 125  ARG A CZ    1 
ATOM   4204  N  NH1   . ARG C 2 125 ? 39.029  107.238 70.184  1.00 24.69  ? 125  ARG A NH1   1 
ATOM   4205  N  NH2   . ARG C 2 125 ? 36.774  107.042 69.813  1.00 31.90  ? 125  ARG A NH2   1 
ATOM   4206  N  N     . ALA C 2 126 ? 39.863  108.216 62.648  1.00 30.24  ? 126  ALA A N     1 
ATOM   4207  C  CA    . ALA C 2 126 ? 41.041  108.635 61.870  1.00 30.55  ? 126  ALA A CA    1 
ATOM   4208  C  C     . ALA C 2 126 ? 40.709  109.321 60.550  1.00 33.46  ? 126  ALA A C     1 
ATOM   4209  O  O     . ALA C 2 126 ? 41.591  109.889 59.893  1.00 32.73  ? 126  ALA A O     1 
ATOM   4210  C  CB    . ALA C 2 126 ? 41.931  107.463 61.605  1.00 35.08  ? 126  ALA A CB    1 
ATOM   4211  N  N     . ARG C 2 127 ? 39.444  109.267 60.145  1.00 29.93  ? 127  ARG A N     1 
ATOM   4212  C  CA    . ARG C 2 127 ? 39.064  109.910 58.895  1.00 36.37  ? 127  ARG A CA    1 
ATOM   4213  C  C     . ARG C 2 127 ? 39.312  111.407 59.016  1.00 34.27  ? 127  ARG A C     1 
ATOM   4214  O  O     . ARG C 2 127 ? 39.557  112.096 58.023  1.00 34.39  ? 127  ARG A O     1 
ATOM   4215  C  CB    . ARG C 2 127 ? 37.593  109.620 58.557  1.00 25.79  ? 127  ARG A CB    1 
ATOM   4216  C  CG    . ARG C 2 127 ? 37.403  108.204 58.008  1.00 40.11  ? 127  ARG A CG    1 
ATOM   4217  C  CD    . ARG C 2 127 ? 35.984  107.623 58.151  1.00 29.07  ? 127  ARG A CD    1 
ATOM   4218  N  NE    . ARG C 2 127 ? 35.101  108.128 57.117  1.00 42.16  ? 127  ARG A NE    1 
ATOM   4219  C  CZ    . ARG C 2 127 ? 34.277  107.387 56.387  1.00 38.35  ? 127  ARG A CZ    1 
ATOM   4220  N  NH1   . ARG C 2 127 ? 33.523  107.977 55.477  1.00 39.32  ? 127  ARG A NH1   1 
ATOM   4221  N  NH2   . ARG C 2 127 ? 34.211  106.071 56.546  1.00 37.85  ? 127  ARG A NH2   1 
ATOM   4222  N  N     . ASN C 2 128 ? 39.290  111.889 60.254  1.00 36.67  ? 128  ASN A N     1 
ATOM   4223  C  CA    . ASN C 2 128 ? 39.482  113.301 60.543  1.00 35.37  ? 128  ASN A CA    1 
ATOM   4224  C  C     . ASN C 2 128 ? 40.932  113.752 60.600  1.00 37.00  ? 128  ASN A C     1 
ATOM   4225  O  O     . ASN C 2 128 ? 41.213  114.919 60.825  1.00 34.28  ? 128  ASN A O     1 
ATOM   4226  C  CB    . ASN C 2 128 ? 38.762  113.666 61.850  1.00 31.45  ? 128  ASN A CB    1 
ATOM   4227  C  CG    . ASN C 2 128 ? 37.258  113.514 61.727  1.00 30.77  ? 128  ASN A CG    1 
ATOM   4228  O  OD1   . ASN C 2 128 ? 36.672  113.980 60.760  1.00 34.28  ? 128  ASN A OD1   1 
ATOM   4229  N  ND2   . ASN C 2 128 ? 36.634  112.862 62.691  1.00 24.86  ? 128  ASN A ND2   1 
ATOM   4230  N  N     . ILE C 2 129 ? 41.868  112.835 60.424  1.00 37.61  ? 129  ILE A N     1 
ATOM   4231  C  CA    . ILE C 2 129 ? 43.258  113.245 60.428  1.00 35.48  ? 129  ILE A CA    1 
ATOM   4232  C  C     . ILE C 2 129 ? 43.550  113.891 59.063  1.00 38.38  ? 129  ILE A C     1 
ATOM   4233  O  O     . ILE C 2 129 ? 43.222  113.337 58.023  1.00 37.42  ? 129  ILE A O     1 
ATOM   4234  C  CB    . ILE C 2 129 ? 44.175  112.042 60.662  1.00 36.98  ? 129  ILE A CB    1 
ATOM   4235  C  CG1   . ILE C 2 129 ? 43.946  111.502 62.082  1.00 35.43  ? 129  ILE A CG1   1 
ATOM   4236  C  CG2   . ILE C 2 129 ? 45.637  112.433 60.421  1.00 32.49  ? 129  ILE A CG2   1 
ATOM   4237  C  CD1   . ILE C 2 129 ? 44.601  110.152 62.340  1.00 31.43  ? 129  ILE A CD1   1 
ATOM   4238  N  N     . PRO C 2 130 ? 44.118  115.105 59.054  1.00 42.63  ? 130  PRO A N     1 
ATOM   4239  C  CA    . PRO C 2 130 ? 44.416  115.748 57.768  1.00 40.84  ? 130  PRO A CA    1 
ATOM   4240  C  C     . PRO C 2 130 ? 45.286  114.830 56.909  1.00 36.11  ? 130  PRO A C     1 
ATOM   4241  O  O     . PRO C 2 130 ? 46.317  114.331 57.368  1.00 39.48  ? 130  PRO A O     1 
ATOM   4242  C  CB    . PRO C 2 130 ? 45.158  117.017 58.181  1.00 37.30  ? 130  PRO A CB    1 
ATOM   4243  C  CG    . PRO C 2 130 ? 44.488  117.357 59.481  1.00 47.01  ? 130  PRO A CG    1 
ATOM   4244  C  CD    . PRO C 2 130 ? 44.406  116.013 60.179  1.00 42.17  ? 130  PRO A CD    1 
ATOM   4245  N  N     . PRO C 2 131 ? 44.890  114.605 55.649  1.00 39.31  ? 131  PRO A N     1 
ATOM   4246  C  CA    . PRO C 2 131 ? 45.648  113.738 54.734  1.00 46.15  ? 131  PRO A CA    1 
ATOM   4247  C  C     . PRO C 2 131 ? 47.150  114.024 54.692  1.00 45.50  ? 131  PRO A C     1 
ATOM   4248  O  O     . PRO C 2 131 ? 47.954  113.087 54.753  1.00 47.81  ? 131  PRO A O     1 
ATOM   4249  C  CB    . PRO C 2 131 ? 44.969  113.968 53.385  1.00 41.04  ? 131  PRO A CB    1 
ATOM   4250  C  CG    . PRO C 2 131 ? 43.564  114.230 53.783  1.00 50.77  ? 131  PRO A CG    1 
ATOM   4251  C  CD    . PRO C 2 131 ? 43.731  115.186 54.959  1.00 46.87  ? 131  PRO A CD    1 
ATOM   4252  N  N     . GLU C 2 132 ? 47.535  115.300 54.604  1.00 41.06  ? 132  GLU A N     1 
ATOM   4253  C  CA    . GLU C 2 132 ? 48.957  115.609 54.565  1.00 45.21  ? 132  GLU A CA    1 
ATOM   4254  C  C     . GLU C 2 132 ? 49.652  115.215 55.853  1.00 36.82  ? 132  GLU A C     1 
ATOM   4255  O  O     . GLU C 2 132 ? 50.803  114.821 55.821  1.00 38.12  ? 132  GLU A O     1 
ATOM   4256  C  CB    . GLU C 2 132 ? 49.226  117.093 54.276  1.00 53.97  ? 132  GLU A CB    1 
ATOM   4257  C  CG    . GLU C 2 132 ? 50.297  117.316 53.154  1.00 72.99  ? 132  GLU A CG    1 
ATOM   4258  C  CD    . GLU C 2 132 ? 51.448  116.261 53.138  1.00 81.56  ? 132  GLU A CD    1 
ATOM   4259  O  OE1   . GLU C 2 132 ? 52.284  116.243 54.075  1.00 87.35  ? 132  GLU A OE1   1 
ATOM   4260  O  OE2   . GLU C 2 132 ? 51.518  115.444 52.182  1.00 76.17  ? 132  GLU A OE2   1 
ATOM   4261  N  N     . GLU C 2 133 ? 48.951  115.312 56.979  1.00 35.18  ? 133  GLU A N     1 
ATOM   4262  C  CA    . GLU C 2 133 ? 49.533  114.939 58.262  1.00 35.69  ? 133  GLU A CA    1 
ATOM   4263  C  C     . GLU C 2 133 ? 49.651  113.427 58.338  1.00 36.50  ? 133  GLU A C     1 
ATOM   4264  O  O     . GLU C 2 133 ? 50.649  112.889 58.841  1.00 37.92  ? 133  GLU A O     1 
ATOM   4265  C  CB    . GLU C 2 133 ? 48.673  115.451 59.422  1.00 40.54  ? 133  GLU A CB    1 
ATOM   4266  C  CG    . GLU C 2 133 ? 48.927  114.737 60.748  1.00 38.54  ? 133  GLU A CG    1 
ATOM   4267  C  CD    . GLU C 2 133 ? 48.146  115.334 61.915  1.00 43.98  ? 133  GLU A CD    1 
ATOM   4268  O  OE1   . GLU C 2 133 ? 47.944  114.627 62.921  1.00 45.48  ? 133  GLU A OE1   1 
ATOM   4269  O  OE2   . GLU C 2 133 ? 47.739  116.512 61.833  1.00 55.89  ? 133  GLU A OE2   1 
ATOM   4270  N  N     . ALA C 2 134 ? 48.640  112.730 57.832  1.00 32.35  ? 134  ALA A N     1 
ATOM   4271  C  CA    . ALA C 2 134 ? 48.673  111.260 57.857  1.00 33.01  ? 134  ALA A CA    1 
ATOM   4272  C  C     . ALA C 2 134 ? 49.881  110.812 57.058  1.00 27.99  ? 134  ALA A C     1 
ATOM   4273  O  O     . ALA C 2 134 ? 50.621  109.926 57.468  1.00 26.22  ? 134  ALA A O     1 
ATOM   4274  C  CB    . ALA C 2 134 ? 47.387  110.674 57.245  1.00 20.92  ? 134  ALA A CB    1 
ATOM   4275  N  N     . GLU C 2 135 ? 50.067  111.449 55.909  1.00 33.07  ? 135  GLU A N     1 
ATOM   4276  C  CA    . GLU C 2 135 ? 51.183  111.145 55.025  1.00 41.98  ? 135  GLU A CA    1 
ATOM   4277  C  C     . GLU C 2 135 ? 52.522  111.374 55.688  1.00 42.33  ? 135  GLU A C     1 
ATOM   4278  O  O     . GLU C 2 135 ? 53.448  110.570 55.527  1.00 46.04  ? 135  GLU A O     1 
ATOM   4279  C  CB    . GLU C 2 135 ? 51.083  111.989 53.752  1.00 45.65  ? 135  GLU A CB    1 
ATOM   4280  C  CG    . GLU C 2 135 ? 49.983  111.501 52.845  1.00 48.73  ? 135  GLU A CG    1 
ATOM   4281  C  CD    . GLU C 2 135 ? 49.984  109.979 52.767  1.00 58.24  ? 135  GLU A CD    1 
ATOM   4282  O  OE1   . GLU C 2 135 ? 51.001  109.432 52.284  1.00 52.94  ? 135  GLU A OE1   1 
ATOM   4283  O  OE2   . GLU C 2 135 ? 48.991  109.341 53.212  1.00 45.99  ? 135  GLU A OE2   1 
ATOM   4284  N  N     . GLU C 2 136 ? 52.622  112.466 56.439  1.00 40.06  ? 136  GLU A N     1 
ATOM   4285  C  CA    . GLU C 2 136 ? 53.861  112.788 57.124  1.00 45.79  ? 136  GLU A CA    1 
ATOM   4286  C  C     . GLU C 2 136 ? 54.125  111.777 58.225  1.00 45.73  ? 136  GLU A C     1 
ATOM   4287  O  O     . GLU C 2 136 ? 55.252  111.295 58.369  1.00 46.95  ? 136  GLU A O     1 
ATOM   4288  C  CB    . GLU C 2 136 ? 53.804  114.198 57.720  1.00 54.97  ? 136  GLU A CB    1 
ATOM   4289  C  CG    . GLU C 2 136 ? 54.861  115.150 57.163  1.00 73.87  ? 136  GLU A CG    1 
ATOM   4290  C  CD    . GLU C 2 136 ? 56.289  114.672 57.415  1.00 77.13  ? 136  GLU A CD    1 
ATOM   4291  O  OE1   . GLU C 2 136 ? 56.677  114.567 58.596  1.00 78.04  ? 136  GLU A OE1   1 
ATOM   4292  O  OE2   . GLU C 2 136 ? 57.023  114.401 56.435  1.00 81.48  ? 136  GLU A OE2   1 
ATOM   4293  N  N     . ARG C 2 137 ? 53.093  111.447 59.001  1.00 38.88  ? 137  ARG A N     1 
ATOM   4294  C  CA    . ARG C 2 137 ? 53.276  110.484 60.075  1.00 35.06  ? 137  ARG A CA    1 
ATOM   4295  C  C     . ARG C 2 137 ? 53.699  109.132 59.521  1.00 43.07  ? 137  ARG A C     1 
ATOM   4296  O  O     . ARG C 2 137 ? 54.398  108.353 60.193  1.00 45.07  ? 137  ARG A O     1 
ATOM   4297  C  CB    . ARG C 2 137 ? 52.007  110.383 60.885  1.00 23.36  ? 137  ARG A CB    1 
ATOM   4298  C  CG    . ARG C 2 137 ? 51.769  111.676 61.629  1.00 30.78  ? 137  ARG A CG    1 
ATOM   4299  C  CD    . ARG C 2 137 ? 50.399  111.800 62.210  1.00 31.09  ? 137  ARG A CD    1 
ATOM   4300  N  NE    . ARG C 2 137 ? 50.172  110.857 63.295  1.00 41.08  ? 137  ARG A NE    1 
ATOM   4301  C  CZ    . ARG C 2 137 ? 49.040  110.806 63.992  1.00 45.25  ? 137  ARG A CZ    1 
ATOM   4302  N  NH1   . ARG C 2 137 ? 48.051  111.647 63.704  1.00 40.67  ? 137  ARG A NH1   1 
ATOM   4303  N  NH2   . ARG C 2 137 ? 48.896  109.918 64.967  1.00 38.23  ? 137  ARG A NH2   1 
ATOM   4304  N  N     . ALA C 2 138 ? 53.301  108.860 58.282  1.00 39.08  ? 138  ALA A N     1 
ATOM   4305  C  CA    . ALA C 2 138 ? 53.673  107.606 57.631  1.00 41.74  ? 138  ALA A CA    1 
ATOM   4306  C  C     . ALA C 2 138 ? 55.151  107.639 57.258  1.00 43.46  ? 138  ALA A C     1 
ATOM   4307  O  O     . ALA C 2 138 ? 55.884  106.685 57.519  1.00 43.16  ? 138  ALA A O     1 
ATOM   4308  C  CB    . ALA C 2 138 ? 52.827  107.373 56.368  1.00 44.44  ? 138  ALA A CB    1 
ATOM   4309  N  N     . ARG C 2 139 ? 55.579  108.736 56.639  1.00 44.81  ? 139  ARG A N     1 
ATOM   4310  C  CA    . ARG C 2 139 ? 56.973  108.887 56.241  1.00 51.37  ? 139  ARG A CA    1 
ATOM   4311  C  C     . ARG C 2 139 ? 57.917  108.809 57.438  1.00 51.66  ? 139  ARG A C     1 
ATOM   4312  O  O     . ARG C 2 139 ? 59.039  108.333 57.309  1.00 63.71  ? 139  ARG A O     1 
ATOM   4313  C  CB    . ARG C 2 139 ? 57.179  110.208 55.499  1.00 49.79  ? 139  ARG A CB    1 
ATOM   4314  C  CG    . ARG C 2 139 ? 56.602  110.209 54.093  1.00 63.62  ? 139  ARG A CG    1 
ATOM   4315  C  CD    . ARG C 2 139 ? 56.548  111.622 53.510  1.00 74.81  ? 139  ARG A CD    1 
ATOM   4316  N  NE    . ARG C 2 139 ? 55.398  112.384 54.000  1.00 83.24  ? 139  ARG A NE    1 
ATOM   4317  C  CZ    . ARG C 2 139 ? 55.242  113.697 53.846  1.00 82.77  ? 139  ARG A CZ    1 
ATOM   4318  N  NH1   . ARG C 2 139 ? 56.173  114.404 53.217  1.00 88.50  ? 139  ARG A NH1   1 
ATOM   4319  N  NH2   . ARG C 2 139 ? 54.152  114.306 54.302  1.00 71.01  ? 139  ARG A NH2   1 
ATOM   4320  N  N     . ARG C 2 140 ? 57.472  109.266 58.602  1.00 51.80  ? 140  ARG A N     1 
ATOM   4321  C  CA    . ARG C 2 140 ? 58.312  109.212 59.791  1.00 45.25  ? 140  ARG A CA    1 
ATOM   4322  C  C     . ARG C 2 140 ? 58.360  107.804 60.356  1.00 46.42  ? 140  ARG A C     1 
ATOM   4323  O  O     . ARG C 2 140 ? 59.039  107.544 61.343  1.00 48.33  ? 140  ARG A O     1 
ATOM   4324  C  CB    . ARG C 2 140 ? 57.797  110.171 60.854  1.00 50.61  ? 140  ARG A CB    1 
ATOM   4325  C  CG    . ARG C 2 140 ? 57.969  111.631 60.506  1.00 56.26  ? 140  ARG A CG    1 
ATOM   4326  C  CD    . ARG C 2 140 ? 57.706  112.500 61.729  1.00 76.39  ? 140  ARG A CD    1 
ATOM   4327  N  NE    . ARG C 2 140 ? 57.861  113.933 61.465  1.00 87.86  ? 140  ARG A NE    1 
ATOM   4328  C  CZ    . ARG C 2 140 ? 58.929  114.494 60.897  1.00 97.51  ? 140  ARG A CZ    1 
ATOM   4329  N  NH1   . ARG C 2 140 ? 59.966  113.753 60.512  1.00 98.70  ? 140  ARG A NH1   1 
ATOM   4330  N  NH2   . ARG C 2 140 ? 58.965  115.810 60.722  1.00 98.18  ? 140  ARG A NH2   1 
ATOM   4331  N  N     . GLY C 2 141 ? 57.615  106.894 59.741  1.00 48.40  ? 141  GLY A N     1 
ATOM   4332  C  CA    . GLY C 2 141 ? 57.634  105.510 60.185  1.00 49.18  ? 141  GLY A CA    1 
ATOM   4333  C  C     . GLY C 2 141 ? 56.658  105.132 61.277  1.00 48.98  ? 141  GLY A C     1 
ATOM   4334  O  O     . GLY C 2 141 ? 56.707  104.019 61.797  1.00 44.29  ? 141  GLY A O     1 
ATOM   4335  N  N     . GLU C 2 142 ? 55.766  106.044 61.629  1.00 47.23  ? 142  GLU A N     1 
ATOM   4336  C  CA    . GLU C 2 142 ? 54.798  105.750 62.670  1.00 48.61  ? 142  GLU A CA    1 
ATOM   4337  C  C     . GLU C 2 142 ? 53.944  104.555 62.223  1.00 44.15  ? 142  GLU A C     1 
ATOM   4338  O  O     . GLU C 2 142 ? 53.321  104.582 61.166  1.00 43.85  ? 142  GLU A O     1 
ATOM   4339  C  CB    . GLU C 2 142 ? 53.916  106.986 62.940  1.00 56.78  ? 142  GLU A CB    1 
ATOM   4340  C  CG    . GLU C 2 142 ? 53.209  106.937 64.304  1.00 64.32  ? 142  GLU A CG    1 
ATOM   4341  C  CD    . GLU C 2 142 ? 52.311  108.133 64.573  1.00 67.04  ? 142  GLU A CD    1 
ATOM   4342  O  OE1   . GLU C 2 142 ? 52.688  109.261 64.168  1.00 60.36  ? 142  GLU A OE1   1 
ATOM   4343  O  OE2   . GLU C 2 142 ? 51.243  107.931 65.212  1.00 59.07  ? 142  GLU A OE2   1 
ATOM   4344  N  N     . PRO C 2 143 ? 53.911  103.489 63.024  1.00 36.57  ? 143  PRO A N     1 
ATOM   4345  C  CA    . PRO C 2 143 ? 53.112  102.333 62.634  1.00 41.30  ? 143  PRO A CA    1 
ATOM   4346  C  C     . PRO C 2 143 ? 51.633  102.667 62.445  1.00 45.11  ? 143  PRO A C     1 
ATOM   4347  O  O     . PRO C 2 143 ? 51.058  103.458 63.198  1.00 48.21  ? 143  PRO A O     1 
ATOM   4348  C  CB    . PRO C 2 143 ? 53.362  101.337 63.764  1.00 41.55  ? 143  PRO A CB    1 
ATOM   4349  C  CG    . PRO C 2 143 ? 53.614  102.205 64.943  1.00 40.94  ? 143  PRO A CG    1 
ATOM   4350  C  CD    . PRO C 2 143 ? 54.484  103.310 64.366  1.00 44.64  ? 143  PRO A CD    1 
ATOM   4351  N  N     . HIS C 2 144 ? 51.021  102.059 61.433  1.00 40.58  ? 144  HIS A N     1 
ATOM   4352  C  CA    . HIS C 2 144 ? 49.611  102.306 61.143  1.00 41.46  ? 144  HIS A CA    1 
ATOM   4353  C  C     . HIS C 2 144 ? 49.008  101.250 60.226  1.00 38.16  ? 144  HIS A C     1 
ATOM   4354  O  O     . HIS C 2 144 ? 49.705  100.369 59.717  1.00 43.38  ? 144  HIS A O     1 
ATOM   4355  C  CB    . HIS C 2 144 ? 49.452  103.666 60.457  1.00 34.82  ? 144  HIS A CB    1 
ATOM   4356  C  CG    . HIS C 2 144 ? 50.204  103.764 59.170  1.00 37.49  ? 144  HIS A CG    1 
ATOM   4357  N  ND1   . HIS C 2 144 ? 51.579  103.782 59.118  1.00 36.67  ? 144  HIS A ND1   1 
ATOM   4358  C  CD2   . HIS C 2 144 ? 49.777  103.799 57.885  1.00 41.20  ? 144  HIS A CD2   1 
ATOM   4359  C  CE1   . HIS C 2 144 ? 51.970  103.829 57.856  1.00 36.82  ? 144  HIS A CE1   1 
ATOM   4360  N  NE2   . HIS C 2 144 ? 50.897  103.840 57.087  1.00 40.32  ? 144  HIS A NE2   1 
ATOM   4361  N  N     . VAL C 2 145 ? 47.700  101.347 60.017  1.00 33.93  ? 145  VAL A N     1 
ATOM   4362  C  CA    . VAL C 2 145 ? 47.026  100.435 59.114  1.00 30.64  ? 145  VAL A CA    1 
ATOM   4363  C  C     . VAL C 2 145 ? 46.297  101.317 58.122  1.00 29.59  ? 145  VAL A C     1 
ATOM   4364  O  O     . VAL C 2 145 ? 46.171  102.515 58.352  1.00 31.87  ? 145  VAL A O     1 
ATOM   4365  C  CB    . VAL C 2 145 ? 45.998  99.575  59.843  1.00 23.02  ? 145  VAL A CB    1 
ATOM   4366  C  CG1   . VAL C 2 145 ? 46.666  98.840  61.004  1.00 32.39  ? 145  VAL A CG1   1 
ATOM   4367  C  CG2   . VAL C 2 145 ? 44.844  100.445 60.307  1.00 21.67  ? 145  VAL A CG2   1 
ATOM   4368  N  N     . ILE C 2 146 ? 45.832  100.737 57.025  1.00 25.96  ? 146  ILE A N     1 
ATOM   4369  C  CA    . ILE C 2 146 ? 45.053  101.483 56.062  1.00 23.98  ? 146  ILE A CA    1 
ATOM   4370  C  C     . ILE C 2 146 ? 43.654  100.870 56.092  1.00 32.75  ? 146  ILE A C     1 
ATOM   4371  O  O     . ILE C 2 146 ? 43.496  99.653  56.037  1.00 33.72  ? 146  ILE A O     1 
ATOM   4372  C  CB    . ILE C 2 146 ? 45.684  101.383 54.702  1.00 27.79  ? 146  ILE A CB    1 
ATOM   4373  C  CG1   . ILE C 2 146 ? 47.031  102.105 54.754  1.00 27.31  ? 146  ILE A CG1   1 
ATOM   4374  C  CG2   . ILE C 2 146 ? 44.757  101.962 53.638  1.00 23.34  ? 146  ILE A CG2   1 
ATOM   4375  C  CD1   . ILE C 2 146 ? 47.831  102.083 53.447  1.00 30.94  ? 146  ILE A CD1   1 
ATOM   4376  N  N     . ARG C 2 147 ? 42.635  101.713 56.202  1.00 34.59  ? 147  ARG A N     1 
ATOM   4377  C  CA    . ARG C 2 147 ? 41.265  101.226 56.287  1.00 24.27  ? 147  ARG A CA    1 
ATOM   4378  C  C     . ARG C 2 147 ? 40.402  101.616 55.094  1.00 31.37  ? 147  ARG A C     1 
ATOM   4379  O  O     . ARG C 2 147 ? 40.661  102.597 54.396  1.00 29.81  ? 147  ARG A O     1 
ATOM   4380  C  CB    . ARG C 2 147 ? 40.610  101.753 57.583  1.00 30.52  ? 147  ARG A CB    1 
ATOM   4381  C  CG    . ARG C 2 147 ? 41.055  101.105 58.928  1.00 25.92  ? 147  ARG A CG    1 
ATOM   4382  C  CD    . ARG C 2 147 ? 40.516  101.930 60.136  1.00 22.23  ? 147  ARG A CD    1 
ATOM   4383  N  NE    . ARG C 2 147 ? 40.823  101.356 61.452  1.00 24.10  ? 147  ARG A NE    1 
ATOM   4384  C  CZ    . ARG C 2 147 ? 40.179  100.324 62.004  1.00 24.77  ? 147  ARG A CZ    1 
ATOM   4385  N  NH1   . ARG C 2 147 ? 39.175  99.735  61.368  1.00 30.19  ? 147  ARG A NH1   1 
ATOM   4386  N  NH2   . ARG C 2 147 ? 40.532  99.868  63.193  1.00 21.69  ? 147  ARG A NH2   1 
ATOM   4387  N  N     . LEU C 2 148 ? 39.359  100.828 54.866  1.00 36.91  ? 148  LEU A N     1 
ATOM   4388  C  CA    . LEU C 2 148 ? 38.414  101.089 53.797  1.00 26.78  ? 148  LEU A CA    1 
ATOM   4389  C  C     . LEU C 2 148 ? 37.607  102.298 54.264  1.00 30.55  ? 148  LEU A C     1 
ATOM   4390  O  O     . LEU C 2 148 ? 37.149  102.339 55.415  1.00 28.76  ? 148  LEU A O     1 
ATOM   4391  C  CB    . LEU C 2 148 ? 37.495  99.879  53.631  1.00 27.17  ? 148  LEU A CB    1 
ATOM   4392  C  CG    . LEU C 2 148 ? 36.262  100.119 52.763  1.00 27.93  ? 148  LEU A CG    1 
ATOM   4393  C  CD1   . LEU C 2 148 ? 36.734  100.404 51.352  1.00 26.91  ? 148  LEU A CD1   1 
ATOM   4394  C  CD2   . LEU C 2 148 ? 35.324  98.912  52.813  1.00 25.32  ? 148  LEU A CD2   1 
ATOM   4395  N  N     . LYS C 2 149 ? 37.437  103.289 53.399  1.00 33.50  ? 149  LYS A N     1 
ATOM   4396  C  CA    . LYS C 2 149 ? 36.657  104.464 53.784  1.00 33.35  ? 149  LYS A CA    1 
ATOM   4397  C  C     . LYS C 2 149 ? 35.244  104.280 53.223  1.00 33.96  ? 149  LYS A C     1 
ATOM   4398  O  O     . LYS C 2 149 ? 34.930  104.696 52.112  1.00 31.27  ? 149  LYS A O     1 
ATOM   4399  C  CB    . LYS C 2 149 ? 37.303  105.736 53.238  1.00 36.02  ? 149  LYS A CB    1 
ATOM   4400  C  CG    . LYS C 2 149 ? 36.698  107.040 53.737  1.00 42.77  ? 149  LYS A CG    1 
ATOM   4401  C  CD    . LYS C 2 149 ? 37.315  108.231 52.995  1.00 60.30  ? 149  LYS A CD    1 
ATOM   4402  C  CE    . LYS C 2 149 ? 36.850  109.602 53.536  1.00 67.75  ? 149  LYS A CE    1 
ATOM   4403  N  NZ    . LYS C 2 149 ? 37.788  110.231 54.533  1.00 72.20  ? 149  LYS A NZ    1 
ATOM   4404  N  N     . VAL C 2 150 ? 34.393  103.625 53.998  1.00 27.85  ? 150  VAL A N     1 
ATOM   4405  C  CA    . VAL C 2 150 ? 33.037  103.382 53.556  1.00 27.09  ? 150  VAL A CA    1 
ATOM   4406  C  C     . VAL C 2 150 ? 32.280  104.668 53.327  1.00 30.02  ? 150  VAL A C     1 
ATOM   4407  O  O     . VAL C 2 150 ? 32.391  105.606 54.109  1.00 31.71  ? 150  VAL A O     1 
ATOM   4408  C  CB    . VAL C 2 150 ? 32.270  102.556 54.580  1.00 25.72  ? 150  VAL A CB    1 
ATOM   4409  C  CG1   . VAL C 2 150 ? 30.804  102.469 54.187  1.00 30.40  ? 150  VAL A CG1   1 
ATOM   4410  C  CG2   . VAL C 2 150 ? 32.894  101.180 54.677  1.00 29.82  ? 150  VAL A CG2   1 
ATOM   4411  N  N     . PRO C 2 151 ? 31.506  104.729 52.238  1.00 32.89  ? 151  PRO A N     1 
ATOM   4412  C  CA    . PRO C 2 151 ? 30.687  105.884 51.846  1.00 31.62  ? 151  PRO A CA    1 
ATOM   4413  C  C     . PRO C 2 151 ? 29.534  105.997 52.827  1.00 33.69  ? 151  PRO A C     1 
ATOM   4414  O  O     . PRO C 2 151 ? 28.632  105.170 52.802  1.00 42.41  ? 151  PRO A O     1 
ATOM   4415  C  CB    . PRO C 2 151 ? 30.155  105.494 50.465  1.00 35.77  ? 151  PRO A CB    1 
ATOM   4416  C  CG    . PRO C 2 151 ? 31.127  104.459 49.979  1.00 40.51  ? 151  PRO A CG    1 
ATOM   4417  C  CD    . PRO C 2 151 ? 31.433  103.671 51.220  1.00 32.54  ? 151  PRO A CD    1 
ATOM   4418  N  N     . ARG C 2 152 ? 29.553  107.003 53.687  1.00 33.25  ? 152  ARG A N     1 
ATOM   4419  C  CA    . ARG C 2 152 ? 28.471  107.177 54.647  1.00 39.97  ? 152  ARG A CA    1 
ATOM   4420  C  C     . ARG C 2 152 ? 27.816  108.557 54.422  1.00 44.10  ? 152  ARG A C     1 
ATOM   4421  O  O     . ARG C 2 152 ? 28.518  109.547 54.139  1.00 36.07  ? 152  ARG A O     1 
ATOM   4422  C  CB    . ARG C 2 152 ? 29.019  107.075 56.065  1.00 40.52  ? 152  ARG A CB    1 
ATOM   4423  C  CG    . ARG C 2 152 ? 29.865  105.855 56.315  1.00 43.12  ? 152  ARG A CG    1 
ATOM   4424  C  CD    . ARG C 2 152 ? 30.375  105.841 57.754  1.00 43.34  ? 152  ARG A CD    1 
ATOM   4425  N  NE    . ARG C 2 152 ? 31.296  104.731 57.977  1.00 42.54  ? 152  ARG A NE    1 
ATOM   4426  C  CZ    . ARG C 2 152 ? 30.948  103.454 57.898  1.00 42.55  ? 152  ARG A CZ    1 
ATOM   4427  N  NH1   . ARG C 2 152 ? 29.690  103.132 57.610  1.00 38.06  ? 152  ARG A NH1   1 
ATOM   4428  N  NH2   . ARG C 2 152 ? 31.862  102.506 58.068  1.00 36.93  ? 152  ARG A NH2   1 
ATOM   4429  N  N     . PRO C 2 153 ? 26.468  108.626 54.485  1.00 36.32  ? 153  PRO A N     1 
ATOM   4430  C  CA    . PRO C 2 153 ? 25.551  107.511 54.748  1.00 36.25  ? 153  PRO A CA    1 
ATOM   4431  C  C     . PRO C 2 153 ? 25.408  106.776 53.423  1.00 42.55  ? 153  PRO A C     1 
ATOM   4432  O  O     . PRO C 2 153 ? 25.891  107.253 52.386  1.00 44.14  ? 153  PRO A O     1 
ATOM   4433  C  CB    . PRO C 2 153 ? 24.268  108.216 55.107  1.00 30.39  ? 153  PRO A CB    1 
ATOM   4434  C  CG    . PRO C 2 153 ? 24.251  109.279 54.046  1.00 35.40  ? 153  PRO A CG    1 
ATOM   4435  C  CD    . PRO C 2 153 ? 25.705  109.813 54.058  1.00 35.35  ? 153  PRO A CD    1 
ATOM   4436  N  N     . GLY C 2 154 ? 24.728  105.638 53.434  1.00 46.02  ? 154  GLY A N     1 
ATOM   4437  C  CA    . GLY C 2 154 ? 24.583  104.914 52.187  1.00 47.48  ? 154  GLY A CA    1 
ATOM   4438  C  C     . GLY C 2 154 ? 23.989  103.515 52.219  1.00 48.92  ? 154  GLY A C     1 
ATOM   4439  O  O     . GLY C 2 154 ? 23.626  102.956 53.267  1.00 43.03  ? 154  GLY A O     1 
ATOM   4440  N  N     . THR C 2 155 ? 23.916  102.935 51.031  1.00 41.53  ? 155  THR A N     1 
ATOM   4441  C  CA    . THR C 2 155 ? 23.333  101.631 50.881  1.00 45.39  ? 155  THR A CA    1 
ATOM   4442  C  C     . THR C 2 155 ? 24.154  100.804 49.868  1.00 45.22  ? 155  THR A C     1 
ATOM   4443  O  O     . THR C 2 155 ? 24.679  101.337 48.889  1.00 44.72  ? 155  THR A O     1 
ATOM   4444  C  CB    . THR C 2 155 ? 21.868  101.842 50.471  1.00 47.29  ? 155  THR A CB    1 
ATOM   4445  O  OG1   . THR C 2 155 ? 21.062  100.839 51.086  1.00 53.17  ? 155  THR A OG1   1 
ATOM   4446  C  CG2   . THR C 2 155 ? 21.710  101.839 48.942  1.00 40.66  ? 155  THR A CG2   1 
ATOM   4447  N  N     . THR C 2 156 ? 24.283  99.504  50.108  1.00 41.29  ? 156  THR A N     1 
ATOM   4448  C  CA    . THR C 2 156 ? 25.103  98.673  49.227  1.00 39.46  ? 156  THR A CA    1 
ATOM   4449  C  C     . THR C 2 156 ? 24.409  97.382  48.854  1.00 39.96  ? 156  THR A C     1 
ATOM   4450  O  O     . THR C 2 156 ? 24.073  96.573  49.713  1.00 37.96  ? 156  THR A O     1 
ATOM   4451  C  CB    . THR C 2 156 ? 26.476  98.354  49.899  1.00 39.23  ? 156  THR A CB    1 
ATOM   4452  O  OG1   . THR C 2 156 ? 27.215  99.571  50.054  1.00 37.94  ? 156  THR A OG1   1 
ATOM   4453  C  CG2   . THR C 2 156 ? 27.296  97.356  49.070  1.00 22.70  ? 156  THR A CG2   1 
ATOM   4454  N  N     . GLU C 2 157 ? 24.211  97.198  47.560  1.00 39.89  ? 157  GLU A N     1 
ATOM   4455  C  CA    . GLU C 2 157 ? 23.540  96.017  47.055  1.00 44.71  ? 157  GLU A CA    1 
ATOM   4456  C  C     . GLU C 2 157 ? 24.477  94.864  46.751  1.00 41.62  ? 157  GLU A C     1 
ATOM   4457  O  O     . GLU C 2 157 ? 25.462  95.032  46.033  1.00 48.23  ? 157  GLU A O     1 
ATOM   4458  C  CB    . GLU C 2 157 ? 22.773  96.363  45.776  1.00 51.51  ? 157  GLU A CB    1 
ATOM   4459  C  CG    . GLU C 2 157 ? 21.309  96.715  45.986  1.00 69.76  ? 157  GLU A CG    1 
ATOM   4460  C  CD    . GLU C 2 157 ? 20.496  96.540  44.713  1.00 77.55  ? 157  GLU A CD    1 
ATOM   4461  O  OE1   . GLU C 2 157 ? 19.248  96.630  44.777  1.00 79.90  ? 157  GLU A OE1   1 
ATOM   4462  O  OE2   . GLU C 2 157 ? 21.110  96.309  43.646  1.00 80.70  ? 157  GLU A OE2   1 
ATOM   4463  N  N     . VAL C 2 158 ? 24.175  93.690  47.294  1.00 40.48  ? 158  VAL A N     1 
ATOM   4464  C  CA    . VAL C 2 158 ? 24.981  92.510  47.014  1.00 30.34  ? 158  VAL A CA    1 
ATOM   4465  C  C     . VAL C 2 158 ? 24.054  91.495  46.384  1.00 38.80  ? 158  VAL A C     1 
ATOM   4466  O  O     . VAL C 2 158 ? 22.918  91.287  46.841  1.00 47.36  ? 158  VAL A O     1 
ATOM   4467  C  CB    . VAL C 2 158 ? 25.612  91.887  48.286  1.00 40.31  ? 158  VAL A CB    1 
ATOM   4468  C  CG1   . VAL C 2 158 ? 26.311  90.577  47.935  1.00 20.58  ? 158  VAL A CG1   1 
ATOM   4469  C  CG2   . VAL C 2 158 ? 26.612  92.863  48.903  1.00 43.30  ? 158  VAL A CG2   1 
ATOM   4470  N  N     . LYS C 2 159 ? 24.529  90.861  45.323  1.00 37.99  ? 159  LYS A N     1 
ATOM   4471  C  CA    . LYS C 2 159 ? 23.725  89.881  44.645  1.00 34.35  ? 159  LYS A CA    1 
ATOM   4472  C  C     . LYS C 2 159 ? 24.345  88.516  44.753  1.00 33.81  ? 159  LYS A C     1 
ATOM   4473  O  O     . LYS C 2 159 ? 25.469  88.310  44.313  1.00 34.50  ? 159  LYS A O     1 
ATOM   4474  C  CB    . LYS C 2 159 ? 23.586  90.259  43.192  1.00 30.48  ? 159  LYS A CB    1 
ATOM   4475  C  CG    . LYS C 2 159 ? 22.789  89.255  42.390  1.00 49.12  ? 159  LYS A CG    1 
ATOM   4476  C  CD    . LYS C 2 159 ? 22.943  89.561  40.904  1.00 55.31  ? 159  LYS A CD    1 
ATOM   4477  C  CE    . LYS C 2 159 ? 22.220  88.542  40.045  1.00 60.76  ? 159  LYS A CE    1 
ATOM   4478  N  NZ    . LYS C 2 159 ? 22.626  88.713  38.618  1.00 69.21  ? 159  LYS A NZ    1 
ATOM   4479  N  N     . ASP C 2 160 ? 23.616  87.599  45.376  1.00 35.96  ? 160  ASP A N     1 
ATOM   4480  C  CA    . ASP C 2 160 ? 24.051  86.213  45.518  1.00 34.95  ? 160  ASP A CA    1 
ATOM   4481  C  C     . ASP C 2 160 ? 23.194  85.454  44.501  1.00 33.93  ? 160  ASP A C     1 
ATOM   4482  O  O     . ASP C 2 160 ? 21.971  85.535  44.543  1.00 33.03  ? 160  ASP A O     1 
ATOM   4483  C  CB    . ASP C 2 160 ? 23.788  85.715  46.946  1.00 33.12  ? 160  ASP A CB    1 
ATOM   4484  C  CG    . ASP C 2 160 ? 24.081  84.225  47.111  1.00 42.61  ? 160  ASP A CG    1 
ATOM   4485  O  OD1   . ASP C 2 160 ? 23.199  83.393  46.782  1.00 40.68  ? 160  ASP A OD1   1 
ATOM   4486  O  OD2   . ASP C 2 160 ? 25.199  83.884  47.561  1.00 29.76  ? 160  ASP A OD2   1 
ATOM   4487  N  N     . GLU C 2 161 ? 23.829  84.744  43.582  1.00 27.95  ? 161  GLU A N     1 
ATOM   4488  C  CA    . GLU C 2 161 ? 23.112  84.021  42.546  1.00 27.64  ? 161  GLU A CA    1 
ATOM   4489  C  C     . GLU C 2 161 ? 22.085  83.002  43.009  1.00 34.74  ? 161  GLU A C     1 
ATOM   4490  O  O     . GLU C 2 161 ? 21.211  82.626  42.233  1.00 39.61  ? 161  GLU A O     1 
ATOM   4491  C  CB    . GLU C 2 161 ? 24.096  83.319  41.609  1.00 27.93  ? 161  GLU A CB    1 
ATOM   4492  C  CG    . GLU C 2 161 ? 25.036  84.271  40.869  1.00 43.93  ? 161  GLU A CG    1 
ATOM   4493  C  CD    . GLU C 2 161 ? 24.293  85.247  39.956  1.00 49.37  ? 161  GLU A CD    1 
ATOM   4494  O  OE1   . GLU C 2 161 ? 23.408  84.784  39.189  1.00 53.05  ? 161  GLU A OE1   1 
ATOM   4495  O  OE2   . GLU C 2 161 ? 24.604  86.462  40.004  1.00 34.58  ? 161  GLU A OE2   1 
ATOM   4496  N  N     . LEU C 2 162 ? 22.166  82.562  44.259  1.00 35.45  ? 162  LEU A N     1 
ATOM   4497  C  CA    . LEU C 2 162 ? 21.228  81.550  44.764  1.00 38.69  ? 162  LEU A CA    1 
ATOM   4498  C  C     . LEU C 2 162 ? 20.149  82.070  45.687  1.00 38.60  ? 162  LEU A C     1 
ATOM   4499  O  O     . LEU C 2 162 ? 19.148  81.392  45.873  1.00 35.76  ? 162  LEU A O     1 
ATOM   4500  C  CB    . LEU C 2 162 ? 21.962  80.454  45.541  1.00 37.95  ? 162  LEU A CB    1 
ATOM   4501  C  CG    . LEU C 2 162 ? 23.263  79.866  45.001  1.00 41.33  ? 162  LEU A CG    1 
ATOM   4502  C  CD1   . LEU C 2 162 ? 23.877  78.978  46.058  1.00 37.09  ? 162  LEU A CD1   1 
ATOM   4503  C  CD2   . LEU C 2 162 ? 23.002  79.081  43.730  1.00 50.61  ? 162  LEU A CD2   1 
ATOM   4504  N  N     . ARG C 2 163 ? 20.369  83.238  46.291  1.00 37.73  ? 163  ARG A N     1 
ATOM   4505  C  CA    . ARG C 2 163 ? 19.409  83.802  47.240  1.00 37.07  ? 163  ARG A CA    1 
ATOM   4506  C  C     . ARG C 2 163 ? 18.730  85.084  46.769  1.00 37.31  ? 163  ARG A C     1 
ATOM   4507  O  O     . ARG C 2 163 ? 17.681  85.449  47.274  1.00 42.74  ? 163  ARG A O     1 
ATOM   4508  C  CB    . ARG C 2 163 ? 20.097  84.055  48.587  1.00 40.86  ? 163  ARG A CB    1 
ATOM   4509  C  CG    . ARG C 2 163 ? 20.762  82.817  49.221  1.00 41.27  ? 163  ARG A CG    1 
ATOM   4510  C  CD    . ARG C 2 163 ? 21.989  83.220  50.051  1.00 31.04  ? 163  ARG A CD    1 
ATOM   4511  N  NE    . ARG C 2 163 ? 23.006  82.160  50.081  1.00 37.80  ? 163  ARG A NE    1 
ATOM   4512  C  CZ    . ARG C 2 163 ? 22.973  81.143  50.929  1.00 43.39  ? 163  ARG A CZ    1 
ATOM   4513  N  NH1   . ARG C 2 163 ? 21.982  81.068  51.799  1.00 67.81  ? 163  ARG A NH1   1 
ATOM   4514  N  NH2   . ARG C 2 163 ? 23.912  80.212  50.927  1.00 46.48  ? 163  ARG A NH2   1 
ATOM   4515  N  N     . GLY C 2 164 ? 19.319  85.759  45.790  1.00 45.89  ? 164  GLY A N     1 
ATOM   4516  C  CA    . GLY C 2 164 ? 18.737  86.996  45.301  1.00 38.08  ? 164  GLY A CA    1 
ATOM   4517  C  C     . GLY C 2 164 ? 19.538  88.195  45.767  1.00 44.30  ? 164  GLY A C     1 
ATOM   4518  O  O     . GLY C 2 164 ? 20.697  88.065  46.171  1.00 44.94  ? 164  GLY A O     1 
ATOM   4519  N  N     . VAL C 2 165 ? 18.927  89.367  45.723  1.00 44.78  ? 165  VAL A N     1 
ATOM   4520  C  CA    . VAL C 2 165 ? 19.602  90.585  46.136  1.00 43.47  ? 165  VAL A CA    1 
ATOM   4521  C  C     . VAL C 2 165 ? 19.410  90.877  47.610  1.00 45.33  ? 165  VAL A C     1 
ATOM   4522  O  O     . VAL C 2 165 ? 18.340  90.643  48.153  1.00 50.83  ? 165  VAL A O     1 
ATOM   4523  C  CB    . VAL C 2 165 ? 19.058  91.781  45.359  1.00 37.94  ? 165  VAL A CB    1 
ATOM   4524  C  CG1   . VAL C 2 165 ? 19.777  93.041  45.783  1.00 45.48  ? 165  VAL A CG1   1 
ATOM   4525  C  CG2   . VAL C 2 165 ? 19.210  91.535  43.881  1.00 38.23  ? 165  VAL A CG2   1 
ATOM   4526  N  N     . VAL C 2 166 ? 20.454  91.370  48.265  1.00 45.73  ? 166  VAL A N     1 
ATOM   4527  C  CA    . VAL C 2 166 ? 20.352  91.763  49.675  1.00 46.53  ? 166  VAL A CA    1 
ATOM   4528  C  C     . VAL C 2 166 ? 20.876  93.178  49.712  1.00 45.42  ? 166  VAL A C     1 
ATOM   4529  O  O     . VAL C 2 166 ? 21.884  93.491  49.081  1.00 44.13  ? 166  VAL A O     1 
ATOM   4530  C  CB    . VAL C 2 166 ? 21.193  90.895  50.614  1.00 51.70  ? 166  VAL A CB    1 
ATOM   4531  C  CG1   . VAL C 2 166 ? 20.524  89.574  50.823  1.00 62.47  ? 166  VAL A CG1   1 
ATOM   4532  C  CG2   . VAL C 2 166 ? 22.561  90.657  50.014  1.00 71.21  ? 166  VAL A CG2   1 
ATOM   4533  N  N     . VAL C 2 167 ? 20.168  94.051  50.409  1.00 50.29  ? 167  VAL A N     1 
ATOM   4534  C  CA    . VAL C 2 167 ? 20.578  95.434  50.477  1.00 48.00  ? 167  VAL A CA    1 
ATOM   4535  C  C     . VAL C 2 167 ? 21.027  95.831  51.863  1.00 53.34  ? 167  VAL A C     1 
ATOM   4536  O  O     . VAL C 2 167 ? 20.221  95.995  52.775  1.00 56.39  ? 167  VAL A O     1 
ATOM   4537  C  CB    . VAL C 2 167 ? 19.455  96.354  50.023  1.00 53.75  ? 167  VAL A CB    1 
ATOM   4538  C  CG1   . VAL C 2 167 ? 19.835  97.799  50.283  1.00 54.76  ? 167  VAL A CG1   1 
ATOM   4539  C  CG2   . VAL C 2 167 ? 19.194  96.139  48.543  1.00 48.99  ? 167  VAL A CG2   1 
ATOM   4540  N  N     . TYR C 2 168 ? 22.337  95.972  52.011  1.00 50.07  ? 168  TYR A N     1 
ATOM   4541  C  CA    . TYR C 2 168 ? 22.908  96.358  53.275  1.00 39.71  ? 168  TYR A CA    1 
ATOM   4542  C  C     . TYR C 2 168 ? 22.870  97.841  53.447  1.00 39.39  ? 168  TYR A C     1 
ATOM   4543  O  O     . TYR C 2 168 ? 22.931  98.614  52.493  1.00 38.90  ? 168  TYR A O     1 
ATOM   4544  C  CB    . TYR C 2 168 ? 24.353  95.925  53.359  1.00 35.10  ? 168  TYR A CB    1 
ATOM   4545  C  CG    . TYR C 2 168 ? 24.507  94.450  53.385  1.00 30.68  ? 168  TYR A CG    1 
ATOM   4546  C  CD1   . TYR C 2 168 ? 24.551  93.767  54.586  1.00 35.95  ? 168  TYR A CD1   1 
ATOM   4547  C  CD2   . TYR C 2 168 ? 24.597  93.722  52.202  1.00 33.72  ? 168  TYR A CD2   1 
ATOM   4548  C  CE1   . TYR C 2 168 ? 24.682  92.382  54.617  1.00 40.73  ? 168  TYR A CE1   1 
ATOM   4549  C  CE2   . TYR C 2 168 ? 24.739  92.338  52.217  1.00 38.62  ? 168  TYR A CE2   1 
ATOM   4550  C  CZ    . TYR C 2 168 ? 24.782  91.675  53.431  1.00 35.62  ? 168  TYR A CZ    1 
ATOM   4551  O  OH    . TYR C 2 168 ? 24.968  90.315  53.472  1.00 37.80  ? 168  TYR A OH    1 
ATOM   4552  N  N     . ASP C 2 169 ? 22.749  98.235  54.696  1.00 39.93  ? 169  ASP A N     1 
ATOM   4553  C  CA    . ASP C 2 169 ? 22.773  99.626  55.033  1.00 43.50  ? 169  ASP A CA    1 
ATOM   4554  C  C     . ASP C 2 169 ? 24.261  99.822  55.302  1.00 42.68  ? 169  ASP A C     1 
ATOM   4555  O  O     . ASP C 2 169 ? 24.884  99.023  56.002  1.00 33.77  ? 169  ASP A O     1 
ATOM   4556  C  CB    . ASP C 2 169 ? 21.988  99.874  56.303  1.00 48.82  ? 169  ASP A CB    1 
ATOM   4557  C  CG    . ASP C 2 169 ? 22.034  101.306 56.714  1.00 64.16  ? 169  ASP A CG    1 
ATOM   4558  O  OD1   . ASP C 2 169 ? 22.092  101.559 57.934  1.00 74.75  ? 169  ASP A OD1   1 
ATOM   4559  O  OD2   . ASP C 2 169 ? 22.009  102.178 55.812  1.00 70.35  ? 169  ASP A OD2   1 
ATOM   4560  N  N     . ASN C 2 170 ? 24.846  100.867 54.753  1.00 34.02  ? 170  ASN A N     1 
ATOM   4561  C  CA    . ASN C 2 170 ? 26.246  101.045 54.979  1.00 30.10  ? 170  ASN A CA    1 
ATOM   4562  C  C     . ASN C 2 170 ? 26.604  101.156 56.449  1.00 37.06  ? 170  ASN A C     1 
ATOM   4563  O  O     . ASN C 2 170 ? 27.715  100.831 56.828  1.00 38.89  ? 170  ASN A O     1 
ATOM   4564  C  CB    . ASN C 2 170 ? 26.734  102.213 54.177  1.00 26.49  ? 170  ASN A CB    1 
ATOM   4565  C  CG    . ASN C 2 170 ? 26.849  101.878 52.704  1.00 38.22  ? 170  ASN A CG    1 
ATOM   4566  O  OD1   . ASN C 2 170 ? 26.327  100.861 52.244  1.00 36.00  ? 170  ASN A OD1   1 
ATOM   4567  N  ND2   . ASN C 2 170 ? 27.532  102.735 51.953  1.00 37.19  ? 170  ASN A ND2   1 
ATOM   4568  N  N     . GLN C 2 171 ? 25.667  101.559 57.294  1.00 35.73  ? 171  GLN A N     1 
ATOM   4569  C  CA    . GLN C 2 171 ? 25.992  101.639 58.709  1.00 40.12  ? 171  GLN A CA    1 
ATOM   4570  C  C     . GLN C 2 171 ? 26.355  100.253 59.244  1.00 43.36  ? 171  GLN A C     1 
ATOM   4571  O  O     . GLN C 2 171 ? 26.989  100.135 60.300  1.00 48.62  ? 171  GLN A O     1 
ATOM   4572  C  CB    . GLN C 2 171 ? 24.829  102.233 59.521  1.00 47.31  ? 171  GLN A CB    1 
ATOM   4573  C  CG    . GLN C 2 171 ? 24.871  103.762 59.656  1.00 67.72  ? 171  GLN A CG    1 
ATOM   4574  C  CD    . GLN C 2 171 ? 24.375  104.500 58.402  1.00 85.38  ? 171  GLN A CD    1 
ATOM   4575  O  OE1   . GLN C 2 171 ? 24.858  104.259 57.286  1.00 91.40  ? 171  GLN A OE1   1 
ATOM   4576  N  NE2   . GLN C 2 171 ? 23.408  105.406 58.586  1.00 78.03  ? 171  GLN A NE2   1 
ATOM   4577  N  N     . GLU C 2 172 ? 25.961  99.206  58.525  1.00 30.96  ? 172  GLU A N     1 
ATOM   4578  C  CA    . GLU C 2 172 ? 26.284  97.837  58.953  1.00 41.21  ? 172  GLU A CA    1 
ATOM   4579  C  C     . GLU C 2 172 ? 27.660  97.405  58.434  1.00 38.59  ? 172  GLU A C     1 
ATOM   4580  O  O     . GLU C 2 172 ? 28.132  96.319  58.770  1.00 41.89  ? 172  GLU A O     1 
ATOM   4581  C  CB    . GLU C 2 172 ? 25.252  96.821  58.426  1.00 46.62  ? 172  GLU A CB    1 
ATOM   4582  C  CG    . GLU C 2 172 ? 23.804  97.345  58.248  1.00 75.04  ? 172  GLU A CG    1 
ATOM   4583  C  CD    . GLU C 2 172 ? 22.900  96.385  57.424  1.00 85.26  ? 172  GLU A CD    1 
ATOM   4584  O  OE1   . GLU C 2 172 ? 21.803  96.804  56.972  1.00 75.06  ? 172  GLU A OE1   1 
ATOM   4585  O  OE2   . GLU C 2 172 ? 23.287  95.207  57.229  1.00 87.23  ? 172  GLU A OE2   1 
ATOM   4586  N  N     . ILE C 2 173 ? 28.292  98.242  57.607  1.00 31.73  ? 173  ILE A N     1 
ATOM   4587  C  CA    . ILE C 2 173 ? 29.587  97.894  57.019  1.00 29.73  ? 173  ILE A CA    1 
ATOM   4588  C  C     . ILE C 2 173 ? 30.714  98.655  57.680  1.00 29.69  ? 173  ILE A C     1 
ATOM   4589  O  O     . ILE C 2 173 ? 30.808  99.865  57.588  1.00 26.99  ? 173  ILE A O     1 
ATOM   4590  C  CB    . ILE C 2 173 ? 29.638  98.222  55.511  1.00 34.85  ? 173  ILE A CB    1 
ATOM   4591  C  CG1   . ILE C 2 173 ? 28.378  97.680  54.813  1.00 34.38  ? 173  ILE A CG1   1 
ATOM   4592  C  CG2   . ILE C 2 173 ? 30.926  97.643  54.887  1.00 22.89  ? 173  ILE A CG2   1 
ATOM   4593  C  CD1   . ILE C 2 173 ? 28.320  98.032  53.341  1.00 38.02  ? 173  ILE A CD1   1 
ATOM   4594  N  N     . PRO C 2 174 ? 31.616  97.948  58.330  1.00 27.64  ? 174  PRO A N     1 
ATOM   4595  C  CA    . PRO C 2 174 ? 32.694  98.702  58.966  1.00 29.93  ? 174  PRO A CA    1 
ATOM   4596  C  C     . PRO C 2 174 ? 33.787  99.242  58.031  1.00 24.86  ? 174  PRO A C     1 
ATOM   4597  O  O     . PRO C 2 174 ? 33.912  98.829  56.890  1.00 30.93  ? 174  PRO A O     1 
ATOM   4598  C  CB    . PRO C 2 174 ? 33.246  97.694  59.968  1.00 41.47  ? 174  PRO A CB    1 
ATOM   4599  C  CG    . PRO C 2 174 ? 33.075  96.377  59.236  1.00 35.02  ? 174  PRO A CG    1 
ATOM   4600  C  CD    . PRO C 2 174 ? 31.708  96.506  58.612  1.00 32.86  ? 174  PRO A CD    1 
ATOM   4601  N  N     . ASP C 2 175 ? 34.550  100.193 58.544  1.00 28.87  ? 175  ASP A N     1 
ATOM   4602  C  CA    . ASP C 2 175 ? 35.700  100.788 57.880  1.00 23.83  ? 175  ASP A CA    1 
ATOM   4603  C  C     . ASP C 2 175 ? 36.842  99.778  58.143  1.00 30.44  ? 175  ASP A C     1 
ATOM   4604  O  O     . ASP C 2 175 ? 37.773  100.043 58.917  1.00 29.69  ? 175  ASP A O     1 
ATOM   4605  C  CB    . ASP C 2 175 ? 36.042  102.115 58.563  1.00 26.94  ? 175  ASP A CB    1 
ATOM   4606  C  CG    . ASP C 2 175 ? 35.309  103.297 57.961  1.00 32.36  ? 175  ASP A CG    1 
ATOM   4607  O  OD1   . ASP C 2 175 ? 34.386  103.099 57.149  1.00 30.55  ? 175  ASP A OD1   1 
ATOM   4608  O  OD2   . ASP C 2 175 ? 35.660  104.439 58.316  1.00 44.33  ? 175  ASP A OD2   1 
ATOM   4609  N  N     . VAL C 2 176 ? 36.768  98.631  57.481  1.00 25.66  ? 176  VAL A N     1 
ATOM   4610  C  CA    . VAL C 2 176 ? 37.723  97.553  57.677  1.00 28.55  ? 176  VAL A CA    1 
ATOM   4611  C  C     . VAL C 2 176 ? 39.179  97.811  57.299  1.00 22.94  ? 176  VAL A C     1 
ATOM   4612  O  O     . VAL C 2 176 ? 39.494  98.512  56.351  1.00 26.10  ? 176  VAL A O     1 
ATOM   4613  C  CB    . VAL C 2 176 ? 37.269  96.271  56.918  1.00 34.32  ? 176  VAL A CB    1 
ATOM   4614  C  CG1   . VAL C 2 176 ? 35.808  95.974  57.217  1.00 32.45  ? 176  VAL A CG1   1 
ATOM   4615  C  CG2   . VAL C 2 176 ? 37.494  96.431  55.390  1.00 25.45  ? 176  VAL A CG2   1 
ATOM   4616  N  N     . VAL C 2 177 ? 40.061  97.219  58.078  1.00 30.40  ? 177  VAL A N     1 
ATOM   4617  C  CA    . VAL C 2 177 ? 41.490  97.293  57.842  1.00 29.20  ? 177  VAL A CA    1 
ATOM   4618  C  C     . VAL C 2 177 ? 41.770  96.548  56.534  1.00 30.32  ? 177  VAL A C     1 
ATOM   4619  O  O     . VAL C 2 177 ? 41.304  95.424  56.337  1.00 21.16  ? 177  VAL A O     1 
ATOM   4620  C  CB    . VAL C 2 177 ? 42.245  96.590  58.976  1.00 32.30  ? 177  VAL A CB    1 
ATOM   4621  C  CG1   . VAL C 2 177 ? 43.722  96.512  58.642  1.00 24.05  ? 177  VAL A CG1   1 
ATOM   4622  C  CG2   . VAL C 2 177 ? 41.989  97.328  60.294  1.00 26.50  ? 177  VAL A CG2   1 
ATOM   4623  N  N     . LEU C 2 178 ? 42.506  97.189  55.639  1.00 28.32  ? 178  LEU A N     1 
ATOM   4624  C  CA    . LEU C 2 178 ? 42.860  96.580  54.373  1.00 28.16  ? 178  LEU A CA    1 
ATOM   4625  C  C     . LEU C 2 178 ? 44.345  96.188  54.381  1.00 31.02  ? 178  LEU A C     1 
ATOM   4626  O  O     . LEU C 2 178 ? 44.723  95.158  53.810  1.00 28.67  ? 178  LEU A O     1 
ATOM   4627  C  CB    . LEU C 2 178 ? 42.561  97.549  53.232  1.00 27.89  ? 178  LEU A CB    1 
ATOM   4628  C  CG    . LEU C 2 178 ? 41.080  97.911  53.163  1.00 31.61  ? 178  LEU A CG    1 
ATOM   4629  C  CD1   . LEU C 2 178 ? 40.863  99.016  52.168  1.00 27.95  ? 178  LEU A CD1   1 
ATOM   4630  C  CD2   . LEU C 2 178 ? 40.265  96.677  52.786  1.00 30.57  ? 178  LEU A CD2   1 
ATOM   4631  N  N     . LEU C 2 179 ? 45.175  97.008  55.028  1.00 21.42  ? 179  LEU A N     1 
ATOM   4632  C  CA    . LEU C 2 179 ? 46.620  96.748  55.123  1.00 31.03  ? 179  LEU A CA    1 
ATOM   4633  C  C     . LEU C 2 179 ? 47.030  96.887  56.585  1.00 31.50  ? 179  LEU A C     1 
ATOM   4634  O  O     . LEU C 2 179 ? 46.837  97.940  57.196  1.00 33.97  ? 179  LEU A O     1 
ATOM   4635  C  CB    . LEU C 2 179 ? 47.429  97.734  54.261  1.00 27.68  ? 179  LEU A CB    1 
ATOM   4636  C  CG    . LEU C 2 179 ? 48.876  97.327  53.967  1.00 32.67  ? 179  LEU A CG    1 
ATOM   4637  C  CD1   . LEU C 2 179 ? 48.843  96.126  53.028  1.00 21.63  ? 179  LEU A CD1   1 
ATOM   4638  C  CD2   . LEU C 2 179 ? 49.652  98.485  53.314  1.00 19.97  ? 179  LEU A CD2   1 
ATOM   4639  N  N     . LYS C 2 180 ? 47.575  95.810  57.149  1.00 36.31  ? 180  LYS A N     1 
ATOM   4640  C  CA    . LYS C 2 180 ? 47.973  95.792  58.545  1.00 30.93  ? 180  LYS A CA    1 
ATOM   4641  C  C     . LYS C 2 180 ? 49.270  96.574  58.753  1.00 35.48  ? 180  LYS A C     1 
ATOM   4642  O  O     . LYS C 2 180 ? 49.954  96.913  57.784  1.00 31.32  ? 180  LYS A O     1 
ATOM   4643  C  CB    . LYS C 2 180 ? 48.135  94.357  59.008  1.00 28.70  ? 180  LYS A CB    1 
ATOM   4644  C  CG    . LYS C 2 180 ? 46.919  93.459  58.739  1.00 32.05  ? 180  LYS A CG    1 
ATOM   4645  C  CD    . LYS C 2 180 ? 47.355  91.989  58.908  1.00 32.92  ? 180  LYS A CD    1 
ATOM   4646  C  CE    . LYS C 2 180 ? 46.262  90.978  58.594  1.00 32.64  ? 180  LYS A CE    1 
ATOM   4647  N  NZ    . LYS C 2 180 ? 46.756  89.563  58.833  1.00 26.47  ? 180  LYS A NZ    1 
ATOM   4648  N  N     . SER C 2 181 ? 49.613  96.857  60.010  1.00 32.52  ? 181  SER A N     1 
ATOM   4649  C  CA    . SER C 2 181 ? 50.821  97.637  60.288  1.00 43.48  ? 181  SER A CA    1 
ATOM   4650  C  C     . SER C 2 181 ? 52.127  96.895  60.014  1.00 38.79  ? 181  SER A C     1 
ATOM   4651  O  O     . SER C 2 181 ? 53.199  97.498  60.008  1.00 46.04  ? 181  SER A O     1 
ATOM   4652  C  CB    . SER C 2 181 ? 50.805  98.202  61.729  1.00 40.66  ? 181  SER A CB    1 
ATOM   4653  O  OG    . SER C 2 181 ? 50.314  97.275  62.675  1.00 35.51  ? 181  SER A OG    1 
ATOM   4654  N  N     . ASP C 2 182 ? 52.040  95.590  59.796  1.00 32.62  ? 182  ASP A N     1 
ATOM   4655  C  CA    . ASP C 2 182 ? 53.222  94.813  59.469  1.00 22.67  ? 182  ASP A CA    1 
ATOM   4656  C  C     . ASP C 2 182 ? 53.330  94.784  57.956  1.00 24.51  ? 182  ASP A C     1 
ATOM   4657  O  O     . ASP C 2 182 ? 54.190  94.120  57.406  1.00 25.47  ? 182  ASP A O     1 
ATOM   4658  C  CB    . ASP C 2 182 ? 53.122  93.389  60.020  1.00 25.35  ? 182  ASP A CB    1 
ATOM   4659  C  CG    . ASP C 2 182 ? 51.978  92.615  59.417  1.00 38.58  ? 182  ASP A CG    1 
ATOM   4660  O  OD1   . ASP C 2 182 ? 51.721  91.470  59.858  1.00 30.88  ? 182  ASP A OD1   1 
ATOM   4661  O  OD2   . ASP C 2 182 ? 51.327  93.161  58.499  1.00 39.82  ? 182  ASP A OD2   1 
ATOM   4662  N  N     . GLY C 2 183 ? 52.449  95.516  57.278  1.00 28.87  ? 183  GLY A N     1 
ATOM   4663  C  CA    . GLY C 2 183 ? 52.493  95.563  55.819  1.00 36.87  ? 183  GLY A CA    1 
ATOM   4664  C  C     . GLY C 2 183 ? 51.857  94.384  55.086  1.00 31.92  ? 183  GLY A C     1 
ATOM   4665  O  O     . GLY C 2 183 ? 52.023  94.208  53.875  1.00 31.52  ? 183  GLY A O     1 
ATOM   4666  N  N     . TYR C 2 184 ? 51.157  93.546  55.826  1.00 24.04  ? 184  TYR A N     1 
ATOM   4667  C  CA    . TYR C 2 184 ? 50.473  92.424  55.214  1.00 28.89  ? 184  TYR A CA    1 
ATOM   4668  C  C     . TYR C 2 184 ? 49.055  92.884  54.987  1.00 30.37  ? 184  TYR A C     1 
ATOM   4669  O  O     . TYR C 2 184 ? 48.531  93.690  55.760  1.00 30.97  ? 184  TYR A O     1 
ATOM   4670  C  CB    . TYR C 2 184 ? 50.439  91.218  56.150  1.00 28.08  ? 184  TYR A CB    1 
ATOM   4671  C  CG    . TYR C 2 184 ? 51.640  90.312  56.069  1.00 28.89  ? 184  TYR A CG    1 
ATOM   4672  C  CD1   . TYR C 2 184 ? 51.573  89.089  55.381  1.00 28.58  ? 184  TYR A CD1   1 
ATOM   4673  C  CD2   . TYR C 2 184 ? 52.834  90.658  56.701  1.00 26.53  ? 184  TYR A CD2   1 
ATOM   4674  C  CE1   . TYR C 2 184 ? 52.681  88.219  55.327  1.00 34.57  ? 184  TYR A CE1   1 
ATOM   4675  C  CE2   . TYR C 2 184 ? 53.933  89.816  56.657  1.00 31.43  ? 184  TYR A CE2   1 
ATOM   4676  C  CZ    . TYR C 2 184 ? 53.856  88.597  55.973  1.00 36.59  ? 184  TYR A CZ    1 
ATOM   4677  O  OH    . TYR C 2 184 ? 54.960  87.783  55.955  1.00 45.11  ? 184  TYR A OH    1 
ATOM   4678  N  N     . PRO C 2 185 ? 48.408  92.389  53.921  1.00 33.64  ? 185  PRO A N     1 
ATOM   4679  C  CA    . PRO C 2 185 ? 47.016  92.813  53.680  1.00 29.69  ? 185  PRO A CA    1 
ATOM   4680  C  C     . PRO C 2 185 ? 46.085  91.988  54.558  1.00 29.43  ? 185  PRO A C     1 
ATOM   4681  O  O     . PRO C 2 185 ? 46.501  90.942  55.067  1.00 30.10  ? 185  PRO A O     1 
ATOM   4682  C  CB    . PRO C 2 185 ? 46.797  92.430  52.227  1.00 31.13  ? 185  PRO A CB    1 
ATOM   4683  C  CG    . PRO C 2 185 ? 47.550  91.078  52.171  1.00 24.06  ? 185  PRO A CG    1 
ATOM   4684  C  CD    . PRO C 2 185 ? 48.868  91.449  52.875  1.00 19.19  ? 185  PRO A CD    1 
ATOM   4685  N  N     . THR C 2 186 ? 44.847  92.443  54.758  1.00 24.59  ? 186  THR A N     1 
ATOM   4686  C  CA    . THR C 2 186 ? 43.908  91.578  55.461  1.00 22.02  ? 186  THR A CA    1 
ATOM   4687  C  C     . THR C 2 186 ? 43.269  90.796  54.317  1.00 25.73  ? 186  THR A C     1 
ATOM   4688  O  O     . THR C 2 186 ? 43.405  91.153  53.129  1.00 20.95  ? 186  THR A O     1 
ATOM   4689  C  CB    . THR C 2 186 ? 42.727  92.306  56.139  1.00 30.57  ? 186  THR A CB    1 
ATOM   4690  O  OG1   . THR C 2 186 ? 42.177  93.248  55.219  1.00 24.51  ? 186  THR A OG1   1 
ATOM   4691  C  CG2   . THR C 2 186 ? 43.144  92.967  57.475  1.00 23.33  ? 186  THR A CG2   1 
ATOM   4692  N  N     . TYR C 2 187 ? 42.551  89.747  54.686  1.00 23.46  ? 187  TYR A N     1 
ATOM   4693  C  CA    . TYR C 2 187 ? 41.822  88.917  53.739  1.00 16.20  ? 187  TYR A CA    1 
ATOM   4694  C  C     . TYR C 2 187 ? 40.961  89.751  52.745  1.00 24.73  ? 187  TYR A C     1 
ATOM   4695  O  O     . TYR C 2 187 ? 40.909  89.453  51.546  1.00 18.31  ? 187  TYR A O     1 
ATOM   4696  C  CB    . TYR C 2 187 ? 40.909  87.969  54.532  1.00 21.68  ? 187  TYR A CB    1 
ATOM   4697  C  CG    . TYR C 2 187 ? 39.761  87.436  53.740  1.00 24.47  ? 187  TYR A CG    1 
ATOM   4698  C  CD1   . TYR C 2 187 ? 39.950  86.417  52.782  1.00 17.71  ? 187  TYR A CD1   1 
ATOM   4699  C  CD2   . TYR C 2 187 ? 38.495  88.016  53.858  1.00 30.78  ? 187  TYR A CD2   1 
ATOM   4700  C  CE1   . TYR C 2 187 ? 38.901  86.000  51.957  1.00 22.75  ? 187  TYR A CE1   1 
ATOM   4701  C  CE2   . TYR C 2 187 ? 37.435  87.613  53.037  1.00 27.67  ? 187  TYR A CE2   1 
ATOM   4702  C  CZ    . TYR C 2 187 ? 37.645  86.607  52.086  1.00 31.55  ? 187  TYR A CZ    1 
ATOM   4703  O  OH    . TYR C 2 187 ? 36.610  86.230  51.252  1.00 38.99  ? 187  TYR A OH    1 
ATOM   4704  N  N     . HIS C 2 188 ? 40.263  90.777  53.242  1.00 25.08  ? 188  HIS A N     1 
ATOM   4705  C  CA    . HIS C 2 188 ? 39.408  91.602  52.380  1.00 26.69  ? 188  HIS A CA    1 
ATOM   4706  C  C     . HIS C 2 188 ? 40.148  92.250  51.232  1.00 29.55  ? 188  HIS A C     1 
ATOM   4707  O  O     . HIS C 2 188 ? 39.676  92.229  50.089  1.00 37.23  ? 188  HIS A O     1 
ATOM   4708  C  CB    . HIS C 2 188 ? 38.692  92.679  53.186  1.00 28.53  ? 188  HIS A CB    1 
ATOM   4709  C  CG    . HIS C 2 188 ? 37.810  92.120  54.252  1.00 27.14  ? 188  HIS A CG    1 
ATOM   4710  N  ND1   . HIS C 2 188 ? 36.776  91.251  53.976  1.00 25.11  ? 188  HIS A ND1   1 
ATOM   4711  C  CD2   . HIS C 2 188 ? 37.852  92.243  55.598  1.00 27.36  ? 188  HIS A CD2   1 
ATOM   4712  C  CE1   . HIS C 2 188 ? 36.220  90.860  55.108  1.00 24.86  ? 188  HIS A CE1   1 
ATOM   4713  N  NE2   . HIS C 2 188 ? 36.855  91.445  56.108  1.00 39.83  ? 188  HIS A NE2   1 
ATOM   4714  N  N     . LEU C 2 189 ? 41.313  92.810  51.514  1.00 21.51  ? 189  LEU A N     1 
ATOM   4715  C  CA    . LEU C 2 189 ? 42.069  93.446  50.455  1.00 25.29  ? 189  LEU A CA    1 
ATOM   4716  C  C     . LEU C 2 189 ? 42.601  92.432  49.423  1.00 30.65  ? 189  LEU A C     1 
ATOM   4717  O  O     . LEU C 2 189 ? 42.349  92.550  48.209  1.00 28.18  ? 189  LEU A O     1 
ATOM   4718  C  CB    . LEU C 2 189 ? 43.240  94.211  51.048  1.00 27.61  ? 189  LEU A CB    1 
ATOM   4719  C  CG    . LEU C 2 189 ? 43.803  95.393  50.272  1.00 35.57  ? 189  LEU A CG    1 
ATOM   4720  C  CD1   . LEU C 2 189 ? 45.251  95.607  50.685  1.00 26.31  ? 189  LEU A CD1   1 
ATOM   4721  C  CD2   . LEU C 2 189 ? 43.688  95.171  48.800  1.00 21.73  ? 189  LEU A CD2   1 
ATOM   4722  N  N     . ALA C 2 190 ? 43.317  91.423  49.906  1.00 23.15  ? 190  ALA A N     1 
ATOM   4723  C  CA    . ALA C 2 190 ? 43.927  90.461  48.998  1.00 21.97  ? 190  ALA A CA    1 
ATOM   4724  C  C     . ALA C 2 190 ? 42.964  89.678  48.118  1.00 26.72  ? 190  ALA A C     1 
ATOM   4725  O  O     . ALA C 2 190 ? 43.220  89.479  46.939  1.00 30.13  ? 190  ALA A O     1 
ATOM   4726  C  CB    . ALA C 2 190 ? 44.822  89.499  49.783  1.00 15.30  ? 190  ALA A CB    1 
ATOM   4727  N  N     . ASN C 2 191 ? 41.863  89.235  48.704  1.00 28.54  ? 191  ASN A N     1 
ATOM   4728  C  CA    . ASN C 2 191 ? 40.861  88.448  48.015  1.00 27.02  ? 191  ASN A CA    1 
ATOM   4729  C  C     . ASN C 2 191 ? 40.336  89.180  46.774  1.00 33.99  ? 191  ASN A C     1 
ATOM   4730  O  O     . ASN C 2 191 ? 40.208  88.579  45.701  1.00 24.06  ? 191  ASN A O     1 
ATOM   4731  C  CB    . ASN C 2 191 ? 39.713  88.158  48.989  1.00 38.62  ? 191  ASN A CB    1 
ATOM   4732  C  CG    . ASN C 2 191 ? 38.873  86.962  48.583  1.00 47.17  ? 191  ASN A CG    1 
ATOM   4733  O  OD1   . ASN C 2 191 ? 37.719  87.121  48.171  1.00 39.93  ? 191  ASN A OD1   1 
ATOM   4734  N  ND2   . ASN C 2 191 ? 39.442  85.750  48.712  1.00 32.50  ? 191  ASN A ND2   1 
ATOM   4735  N  N     . VAL C 2 192 ? 40.050  90.472  46.911  1.00 28.79  ? 192  VAL A N     1 
ATOM   4736  C  CA    . VAL C 2 192 ? 39.532  91.245  45.789  1.00 26.21  ? 192  VAL A CA    1 
ATOM   4737  C  C     . VAL C 2 192 ? 40.591  91.529  44.754  1.00 25.04  ? 192  VAL A C     1 
ATOM   4738  O  O     . VAL C 2 192 ? 40.333  91.419  43.551  1.00 21.50  ? 192  VAL A O     1 
ATOM   4739  C  CB    . VAL C 2 192 ? 38.940  92.586  46.249  1.00 35.44  ? 192  VAL A CB    1 
ATOM   4740  C  CG1   . VAL C 2 192 ? 38.661  93.483  45.036  1.00 20.32  ? 192  VAL A CG1   1 
ATOM   4741  C  CG2   . VAL C 2 192 ? 37.639  92.322  47.030  1.00 33.35  ? 192  VAL A CG2   1 
ATOM   4742  N  N     . VAL C 2 193 ? 41.785  91.893  45.218  1.00 26.77  ? 193  VAL A N     1 
ATOM   4743  C  CA    . VAL C 2 193 ? 42.906  92.186  44.302  1.00 20.76  ? 193  VAL A CA    1 
ATOM   4744  C  C     . VAL C 2 193 ? 43.271  90.934  43.491  1.00 23.12  ? 193  VAL A C     1 
ATOM   4745  O  O     . VAL C 2 193 ? 43.346  90.976  42.264  1.00 23.74  ? 193  VAL A O     1 
ATOM   4746  C  CB    . VAL C 2 193 ? 44.168  92.737  45.091  1.00 31.08  ? 193  VAL A CB    1 
ATOM   4747  C  CG1   . VAL C 2 193 ? 45.394  92.763  44.192  1.00 27.88  ? 193  VAL A CG1   1 
ATOM   4748  C  CG2   . VAL C 2 193 ? 43.893  94.194  45.630  1.00 13.88  ? 193  VAL A CG2   1 
ATOM   4749  N  N     . ASP C 2 194 ? 43.445  89.803  44.159  1.00 19.52  ? 194  ASP A N     1 
ATOM   4750  C  CA    . ASP C 2 194 ? 43.784  88.589  43.441  1.00 24.57  ? 194  ASP A CA    1 
ATOM   4751  C  C     . ASP C 2 194 ? 42.676  87.950  42.610  1.00 28.73  ? 194  ASP A C     1 
ATOM   4752  O  O     . ASP C 2 194 ? 42.962  87.403  41.544  1.00 36.96  ? 194  ASP A O     1 
ATOM   4753  C  CB    . ASP C 2 194 ? 44.401  87.570  44.397  1.00 29.42  ? 194  ASP A CB    1 
ATOM   4754  C  CG    . ASP C 2 194 ? 45.725  88.066  44.987  1.00 27.52  ? 194  ASP A CG    1 
ATOM   4755  O  OD1   . ASP C 2 194 ? 46.203  87.497  45.993  1.00 23.07  ? 194  ASP A OD1   1 
ATOM   4756  O  OD2   . ASP C 2 194 ? 46.279  89.029  44.434  1.00 27.67  ? 194  ASP A OD2   1 
ATOM   4757  N  N     . ASP C 2 195 ? 41.426  87.983  43.059  1.00 21.23  ? 195  ASP A N     1 
ATOM   4758  C  CA    . ASP C 2 195 ? 40.386  87.391  42.223  1.00 23.43  ? 195  ASP A CA    1 
ATOM   4759  C  C     . ASP C 2 195 ? 40.363  88.188  40.923  1.00 22.50  ? 195  ASP A C     1 
ATOM   4760  O  O     . ASP C 2 195 ? 40.202  87.640  39.832  1.00 28.46  ? 195  ASP A O     1 
ATOM   4761  C  CB    . ASP C 2 195 ? 39.003  87.457  42.893  1.00 17.86  ? 195  ASP A CB    1 
ATOM   4762  C  CG    . ASP C 2 195 ? 38.819  86.387  43.974  1.00 31.10  ? 195  ASP A CG    1 
ATOM   4763  O  OD1   . ASP C 2 195 ? 37.909  86.568  44.819  1.00 18.23  ? 195  ASP A OD1   1 
ATOM   4764  O  OD2   . ASP C 2 195 ? 39.566  85.366  43.974  1.00 26.42  ? 195  ASP A OD2   1 
ATOM   4765  N  N     . HIS C 2 196 ? 40.540  89.491  41.036  1.00 21.22  ? 196  HIS A N     1 
ATOM   4766  C  CA    . HIS C 2 196 ? 40.526  90.338  39.851  1.00 25.22  ? 196  HIS A CA    1 
ATOM   4767  C  C     . HIS C 2 196 ? 41.673  90.071  38.850  1.00 26.47  ? 196  HIS A C     1 
ATOM   4768  O  O     . HIS C 2 196 ? 41.444  89.875  37.660  1.00 26.32  ? 196  HIS A O     1 
ATOM   4769  C  CB    . HIS C 2 196 ? 40.566  91.797  40.280  1.00 23.05  ? 196  HIS A CB    1 
ATOM   4770  C  CG    . HIS C 2 196 ? 40.780  92.743  39.142  1.00 37.74  ? 196  HIS A CG    1 
ATOM   4771  N  ND1   . HIS C 2 196 ? 39.801  93.024  38.212  1.00 27.38  ? 196  HIS A ND1   1 
ATOM   4772  C  CD2   . HIS C 2 196 ? 41.875  93.444  38.760  1.00 34.02  ? 196  HIS A CD2   1 
ATOM   4773  C  CE1   . HIS C 2 196 ? 40.282  93.857  37.310  1.00 29.86  ? 196  HIS A CE1   1 
ATOM   4774  N  NE2   . HIS C 2 196 ? 41.537  94.130  37.619  1.00 38.77  ? 196  HIS A NE2   1 
ATOM   4775  N  N     . LEU C 2 197 ? 42.897  90.095  39.363  1.00 19.27  ? 197  LEU A N     1 
ATOM   4776  C  CA    . LEU C 2 197 ? 44.115  89.888  38.601  1.00 27.12  ? 197  LEU A CA    1 
ATOM   4777  C  C     . LEU C 2 197 ? 44.212  88.452  38.062  1.00 32.89  ? 197  LEU A C     1 
ATOM   4778  O  O     . LEU C 2 197 ? 44.805  88.217  37.009  1.00 36.26  ? 197  LEU A O     1 
ATOM   4779  C  CB    . LEU C 2 197 ? 45.329  90.219  39.500  1.00 24.99  ? 197  LEU A CB    1 
ATOM   4780  C  CG    . LEU C 2 197 ? 46.034  91.596  39.471  1.00 24.04  ? 197  LEU A CG    1 
ATOM   4781  C  CD1   . LEU C 2 197 ? 45.179  92.647  38.883  1.00 35.19  ? 197  LEU A CD1   1 
ATOM   4782  C  CD2   . LEU C 2 197 ? 46.462  91.987  40.856  1.00 29.73  ? 197  LEU A CD2   1 
ATOM   4783  N  N     . MET C 2 198 ? 43.651  87.488  38.786  1.00 22.57  ? 198  MET A N     1 
ATOM   4784  C  CA    . MET C 2 198 ? 43.687  86.112  38.328  1.00 24.25  ? 198  MET A CA    1 
ATOM   4785  C  C     . MET C 2 198 ? 42.447  85.847  37.462  1.00 27.69  ? 198  MET A C     1 
ATOM   4786  O  O     . MET C 2 198 ? 42.220  84.726  36.998  1.00 37.38  ? 198  MET A O     1 
ATOM   4787  C  CB    . MET C 2 198 ? 43.746  85.148  39.526  1.00 23.89  ? 198  MET A CB    1 
ATOM   4788  C  CG    . MET C 2 198 ? 45.031  85.248  40.281  1.00 21.00  ? 198  MET A CG    1 
ATOM   4789  S  SD    . MET C 2 198 ? 45.167  84.110  41.624  1.00 29.50  ? 198  MET A SD    1 
ATOM   4790  C  CE    . MET C 2 198 ? 46.903  84.409  42.097  1.00 30.05  ? 198  MET A CE    1 
ATOM   4791  N  N     . GLY C 2 199 ? 41.653  86.896  37.264  1.00 29.71  ? 199  GLY A N     1 
ATOM   4792  C  CA    . GLY C 2 199 ? 40.463  86.822  36.439  1.00 23.28  ? 199  GLY A CA    1 
ATOM   4793  C  C     . GLY C 2 199 ? 39.281  85.990  36.907  1.00 32.51  ? 199  GLY A C     1 
ATOM   4794  O  O     . GLY C 2 199 ? 38.501  85.569  36.052  1.00 33.94  ? 199  GLY A O     1 
ATOM   4795  N  N     . VAL C 2 200 ? 39.095  85.748  38.211  1.00 27.54  ? 200  VAL A N     1 
ATOM   4796  C  CA    . VAL C 2 200 ? 37.942  84.923  38.597  1.00 25.83  ? 200  VAL A CA    1 
ATOM   4797  C  C     . VAL C 2 200 ? 36.584  85.571  38.278  1.00 24.71  ? 200  VAL A C     1 
ATOM   4798  O  O     . VAL C 2 200 ? 36.349  86.766  38.458  1.00 20.53  ? 200  VAL A O     1 
ATOM   4799  C  CB    . VAL C 2 200 ? 37.979  84.439  40.103  1.00 30.04  ? 200  VAL A CB    1 
ATOM   4800  C  CG1   . VAL C 2 200 ? 39.394  84.460  40.639  1.00 19.63  ? 200  VAL A CG1   1 
ATOM   4801  C  CG2   . VAL C 2 200 ? 36.982  85.208  40.944  1.00 34.46  ? 200  VAL A CG2   1 
ATOM   4802  N  N     . THR C 2 201 ? 35.658  84.774  37.797  1.00 25.68  ? 201  THR A N     1 
ATOM   4803  C  CA    . THR C 2 201 ? 34.400  85.371  37.427  1.00 22.87  ? 201  THR A CA    1 
ATOM   4804  C  C     . THR C 2 201 ? 33.301  84.834  38.301  1.00 35.36  ? 201  THR A C     1 
ATOM   4805  O  O     . THR C 2 201 ? 32.195  85.398  38.356  1.00 33.44  ? 201  THR A O     1 
ATOM   4806  C  CB    . THR C 2 201 ? 34.117  84.995  36.021  1.00 27.83  ? 201  THR A CB    1 
ATOM   4807  O  OG1   . THR C 2 201 ? 34.155  83.566  35.928  1.00 17.34  ? 201  THR A OG1   1 
ATOM   4808  C  CG2   . THR C 2 201 ? 35.200  85.554  35.106  1.00 28.97  ? 201  THR A CG2   1 
ATOM   4809  N  N     . ASP C 2 202 ? 33.613  83.733  38.983  1.00 29.22  ? 202  ASP A N     1 
ATOM   4810  C  CA    . ASP C 2 202 ? 32.637  83.073  39.834  1.00 22.77  ? 202  ASP A CA    1 
ATOM   4811  C  C     . ASP C 2 202 ? 33.198  82.692  41.202  1.00 32.77  ? 202  ASP A C     1 
ATOM   4812  O  O     . ASP C 2 202 ? 34.028  81.777  41.335  1.00 24.70  ? 202  ASP A O     1 
ATOM   4813  C  CB    . ASP C 2 202 ? 32.105  81.837  39.108  1.00 32.54  ? 202  ASP A CB    1 
ATOM   4814  C  CG    . ASP C 2 202 ? 31.331  82.190  37.817  1.00 34.65  ? 202  ASP A CG    1 
ATOM   4815  O  OD1   . ASP C 2 202 ? 30.083  82.124  37.809  1.00 35.60  ? 202  ASP A OD1   1 
ATOM   4816  O  OD2   . ASP C 2 202 ? 31.969  82.544  36.815  1.00 31.36  ? 202  ASP A OD2   1 
ATOM   4817  N  N     . VAL C 2 203 ? 32.751  83.418  42.220  1.00 27.43  ? 203  VAL A N     1 
ATOM   4818  C  CA    . VAL C 2 203 ? 33.174  83.152  43.577  1.00 29.36  ? 203  VAL A CA    1 
ATOM   4819  C  C     . VAL C 2 203 ? 32.160  82.239  44.277  1.00 32.56  ? 203  VAL A C     1 
ATOM   4820  O  O     . VAL C 2 203 ? 31.053  82.673  44.608  1.00 26.41  ? 203  VAL A O     1 
ATOM   4821  C  CB    . VAL C 2 203 ? 33.291  84.455  44.367  1.00 34.61  ? 203  VAL A CB    1 
ATOM   4822  C  CG1   . VAL C 2 203 ? 33.828  84.174  45.787  1.00 22.17  ? 203  VAL A CG1   1 
ATOM   4823  C  CG2   . VAL C 2 203 ? 34.197  85.402  43.614  1.00 19.95  ? 203  VAL A CG2   1 
ATOM   4824  N  N     . ILE C 2 204 ? 32.522  80.972  44.469  1.00 24.31  ? 204  ILE A N     1 
ATOM   4825  C  CA    . ILE C 2 204 ? 31.643  80.021  45.153  1.00 21.47  ? 204  ILE A CA    1 
ATOM   4826  C  C     . ILE C 2 204 ? 32.372  79.802  46.459  1.00 26.02  ? 204  ILE A C     1 
ATOM   4827  O  O     . ILE C 2 204 ? 33.536  79.385  46.478  1.00 22.91  ? 204  ILE A O     1 
ATOM   4828  C  CB    . ILE C 2 204 ? 31.553  78.695  44.396  1.00 30.21  ? 204  ILE A CB    1 
ATOM   4829  C  CG1   . ILE C 2 204 ? 31.159  78.965  42.943  1.00 26.65  ? 204  ILE A CG1   1 
ATOM   4830  C  CG2   . ILE C 2 204 ? 30.550  77.767  45.068  1.00 23.31  ? 204  ILE A CG2   1 
ATOM   4831  C  CD1   . ILE C 2 204 ? 31.329  77.764  42.072  1.00 23.85  ? 204  ILE A CD1   1 
ATOM   4832  N  N     . ARG C 2 205 ? 31.707  80.100  47.557  1.00 25.11  ? 205  ARG A N     1 
ATOM   4833  C  CA    . ARG C 2 205 ? 32.348  79.965  48.853  1.00 28.66  ? 205  ARG A CA    1 
ATOM   4834  C  C     . ARG C 2 205 ? 31.289  79.702  49.931  1.00 27.88  ? 205  ARG A C     1 
ATOM   4835  O  O     . ARG C 2 205 ? 30.088  79.773  49.663  1.00 28.71  ? 205  ARG A O     1 
ATOM   4836  C  CB    . ARG C 2 205 ? 33.135  81.251  49.168  1.00 30.60  ? 205  ARG A CB    1 
ATOM   4837  C  CG    . ARG C 2 205 ? 32.330  82.267  49.922  1.00 37.97  ? 205  ARG A CG    1 
ATOM   4838  C  CD    . ARG C 2 205 ? 32.244  83.627  49.261  1.00 39.78  ? 205  ARG A CD    1 
ATOM   4839  N  NE    . ARG C 2 205 ? 33.496  84.363  49.241  1.00 33.91  ? 205  ARG A NE    1 
ATOM   4840  C  CZ    . ARG C 2 205 ? 33.583  85.697  49.211  1.00 37.19  ? 205  ARG A CZ    1 
ATOM   4841  N  NH1   . ARG C 2 205 ? 32.501  86.454  49.216  1.00 31.56  ? 205  ARG A NH1   1 
ATOM   4842  N  NH2   . ARG C 2 205 ? 34.768  86.277  49.122  1.00 41.82  ? 205  ARG A NH2   1 
ATOM   4843  N  N     . ALA C 2 206 ? 31.742  79.420  51.148  1.00 18.67  ? 206  ALA A N     1 
ATOM   4844  C  CA    . ALA C 2 206 ? 30.840  79.102  52.217  1.00 15.79  ? 206  ALA A CA    1 
ATOM   4845  C  C     . ALA C 2 206 ? 30.105  80.328  52.701  1.00 24.90  ? 206  ALA A C     1 
ATOM   4846  O  O     . ALA C 2 206 ? 30.648  81.440  52.729  1.00 23.69  ? 206  ALA A O     1 
ATOM   4847  C  CB    . ALA C 2 206 ? 31.601  78.448  53.376  1.00 17.06  ? 206  ALA A CB    1 
ATOM   4848  N  N     . GLU C 2 207 ? 28.861  80.089  53.099  1.00 29.28  ? 207  GLU A N     1 
ATOM   4849  C  CA    . GLU C 2 207 ? 27.954  81.098  53.603  1.00 29.49  ? 207  GLU A CA    1 
ATOM   4850  C  C     . GLU C 2 207 ? 28.606  81.988  54.684  1.00 30.08  ? 207  GLU A C     1 
ATOM   4851  O  O     . GLU C 2 207 ? 28.269  83.159  54.811  1.00 31.49  ? 207  GLU A O     1 
ATOM   4852  C  CB    . GLU C 2 207 ? 26.698  80.398  54.148  1.00 29.55  ? 207  GLU A CB    1 
ATOM   4853  C  CG    . GLU C 2 207 ? 25.420  81.178  53.934  1.00 46.17  ? 207  GLU A CG    1 
ATOM   4854  C  CD    . GLU C 2 207 ? 24.175  80.513  54.555  1.00 57.68  ? 207  GLU A CD    1 
ATOM   4855  O  OE1   . GLU C 2 207 ? 23.066  81.065  54.376  1.00 53.10  ? 207  GLU A OE1   1 
ATOM   4856  O  OE2   . GLU C 2 207 ? 24.294  79.457  55.216  1.00 50.99  ? 207  GLU A OE2   1 
ATOM   4857  N  N     . GLU C 2 208 ? 29.551  81.462  55.454  1.00 29.73  ? 208  GLU A N     1 
ATOM   4858  C  CA    . GLU C 2 208 ? 30.186  82.303  56.475  1.00 34.03  ? 208  GLU A CA    1 
ATOM   4859  C  C     . GLU C 2 208 ? 30.754  83.611  55.916  1.00 29.06  ? 208  GLU A C     1 
ATOM   4860  O  O     . GLU C 2 208 ? 31.021  84.526  56.676  1.00 35.29  ? 208  GLU A O     1 
ATOM   4861  C  CB    . GLU C 2 208 ? 31.299  81.542  57.208  1.00 33.74  ? 208  GLU A CB    1 
ATOM   4862  C  CG    . GLU C 2 208 ? 32.536  81.246  56.365  1.00 53.06  ? 208  GLU A CG    1 
ATOM   4863  C  CD    . GLU C 2 208 ? 33.604  80.507  57.156  1.00 57.16  ? 208  GLU A CD    1 
ATOM   4864  O  OE1   . GLU C 2 208 ? 34.181  81.094  58.111  1.00 61.39  ? 208  GLU A OE1   1 
ATOM   4865  O  OE2   . GLU C 2 208 ? 33.856  79.333  56.822  1.00 47.93  ? 208  GLU A OE2   1 
ATOM   4866  N  N     . TRP C 2 209 ? 30.919  83.702  54.595  1.00 31.04  ? 209  TRP A N     1 
ATOM   4867  C  CA    . TRP C 2 209 ? 31.454  84.902  53.938  1.00 29.12  ? 209  TRP A CA    1 
ATOM   4868  C  C     . TRP C 2 209 ? 30.384  85.861  53.377  1.00 32.09  ? 209  TRP A C     1 
ATOM   4869  O  O     . TRP C 2 209 ? 30.722  86.948  52.897  1.00 28.05  ? 209  TRP A O     1 
ATOM   4870  C  CB    . TRP C 2 209 ? 32.379  84.505  52.786  1.00 23.46  ? 209  TRP A CB    1 
ATOM   4871  C  CG    . TRP C 2 209 ? 33.496  83.656  53.218  1.00 28.90  ? 209  TRP A CG    1 
ATOM   4872  C  CD1   . TRP C 2 209 ? 33.619  82.310  53.042  1.00 24.15  ? 209  TRP A CD1   1 
ATOM   4873  C  CD2   . TRP C 2 209 ? 34.619  84.064  53.985  1.00 22.66  ? 209  TRP A CD2   1 
ATOM   4874  N  NE1   . TRP C 2 209 ? 34.741  81.854  53.662  1.00 28.83  ? 209  TRP A NE1   1 
ATOM   4875  C  CE2   . TRP C 2 209 ? 35.381  82.910  54.249  1.00 32.57  ? 209  TRP A CE2   1 
ATOM   4876  C  CE3   . TRP C 2 209 ? 35.056  85.296  54.480  1.00 40.51  ? 209  TRP A CE3   1 
ATOM   4877  C  CZ2   . TRP C 2 209 ? 36.568  82.947  54.988  1.00 35.28  ? 209  TRP A CZ2   1 
ATOM   4878  C  CZ3   . TRP C 2 209 ? 36.230  85.339  55.212  1.00 35.95  ? 209  TRP A CZ3   1 
ATOM   4879  C  CH2   . TRP C 2 209 ? 36.973  84.168  55.458  1.00 33.60  ? 209  TRP A CH2   1 
ATOM   4880  N  N     . LEU C 2 210 ? 29.113  85.462  53.437  1.00 29.91  ? 210  LEU A N     1 
ATOM   4881  C  CA    . LEU C 2 210 ? 28.024  86.275  52.890  1.00 29.56  ? 210  LEU A CA    1 
ATOM   4882  C  C     . LEU C 2 210 ? 28.005  87.723  53.350  1.00 28.06  ? 210  LEU A C     1 
ATOM   4883  O  O     . LEU C 2 210 ? 27.972  88.617  52.514  1.00 27.27  ? 210  LEU A O     1 
ATOM   4884  C  CB    . LEU C 2 210 ? 26.665  85.640  53.193  1.00 32.08  ? 210  LEU A CB    1 
ATOM   4885  C  CG    . LEU C 2 210 ? 25.408  86.263  52.569  1.00 34.23  ? 210  LEU A CG    1 
ATOM   4886  C  CD1   . LEU C 2 210 ? 25.482  86.298  51.048  1.00 34.26  ? 210  LEU A CD1   1 
ATOM   4887  C  CD2   . LEU C 2 210 ? 24.237  85.428  52.974  1.00 41.77  ? 210  LEU A CD2   1 
ATOM   4888  N  N     . VAL C 2 211 ? 28.036  87.961  54.660  1.00 29.70  ? 211  VAL A N     1 
ATOM   4889  C  CA    . VAL C 2 211 ? 28.007  89.333  55.171  1.00 31.30  ? 211  VAL A CA    1 
ATOM   4890  C  C     . VAL C 2 211 ? 29.284  90.104  54.883  1.00 35.87  ? 211  VAL A C     1 
ATOM   4891  O  O     . VAL C 2 211 ? 29.297  91.339  54.945  1.00 37.68  ? 211  VAL A O     1 
ATOM   4892  C  CB    . VAL C 2 211 ? 27.779  89.405  56.680  1.00 39.36  ? 211  VAL A CB    1 
ATOM   4893  C  CG1   . VAL C 2 211 ? 26.427  88.805  57.016  1.00 38.16  ? 211  VAL A CG1   1 
ATOM   4894  C  CG2   . VAL C 2 211 ? 28.921  88.686  57.411  1.00 43.40  ? 211  VAL A CG2   1 
ATOM   4895  N  N     . SER C 2 212 ? 30.364  89.409  54.569  1.00 20.83  ? 212  SER A N     1 
ATOM   4896  C  CA    . SER C 2 212 ? 31.545  90.172  54.271  1.00 26.75  ? 212  SER A CA    1 
ATOM   4897  C  C     . SER C 2 212 ? 31.507  90.575  52.778  1.00 23.98  ? 212  SER A C     1 
ATOM   4898  O  O     . SER C 2 212 ? 32.251  91.463  52.351  1.00 23.11  ? 212  SER A O     1 
ATOM   4899  C  CB    . SER C 2 212 ? 32.810  89.379  54.639  1.00 26.16  ? 212  SER A CB    1 
ATOM   4900  O  OG    . SER C 2 212 ? 33.235  88.620  53.532  1.00 56.83  ? 212  SER A OG    1 
ATOM   4901  N  N     . THR C 2 213 ? 30.590  89.978  52.004  1.00 21.04  ? 213  THR A N     1 
ATOM   4902  C  CA    . THR C 2 213 ? 30.498  90.317  50.585  1.00 27.35  ? 213  THR A CA    1 
ATOM   4903  C  C     . THR C 2 213 ? 30.277  91.813  50.276  1.00 31.69  ? 213  THR A C     1 
ATOM   4904  O  O     . THR C 2 213 ? 30.870  92.333  49.328  1.00 26.20  ? 213  THR A O     1 
ATOM   4905  C  CB    . THR C 2 213 ? 29.436  89.472  49.863  1.00 32.26  ? 213  THR A CB    1 
ATOM   4906  O  OG1   . THR C 2 213 ? 29.751  88.079  50.029  1.00 30.88  ? 213  THR A OG1   1 
ATOM   4907  C  CG2   . THR C 2 213 ? 29.435  89.798  48.355  1.00 27.21  ? 213  THR A CG2   1 
ATOM   4908  N  N     . PRO C 2 214 ? 29.443  92.526  51.072  1.00 28.53  ? 214  PRO A N     1 
ATOM   4909  C  CA    . PRO C 2 214 ? 29.270  93.946  50.753  1.00 30.12  ? 214  PRO A CA    1 
ATOM   4910  C  C     . PRO C 2 214 ? 30.609  94.707  50.886  1.00 32.28  ? 214  PRO A C     1 
ATOM   4911  O  O     . PRO C 2 214 ? 30.823  95.701  50.202  1.00 38.99  ? 214  PRO A O     1 
ATOM   4912  C  CB    . PRO C 2 214 ? 28.188  94.410  51.752  1.00 25.34  ? 214  PRO A CB    1 
ATOM   4913  C  CG    . PRO C 2 214 ? 28.428  93.521  52.946  1.00 31.68  ? 214  PRO A CG    1 
ATOM   4914  C  CD    . PRO C 2 214 ? 28.671  92.162  52.277  1.00 34.63  ? 214  PRO A CD    1 
ATOM   4915  N  N     . ILE C 2 215 ? 31.516  94.259  51.755  1.00 32.16  ? 215  ILE A N     1 
ATOM   4916  C  CA    . ILE C 2 215 ? 32.821  94.937  51.847  1.00 26.63  ? 215  ILE A CA    1 
ATOM   4917  C  C     . ILE C 2 215 ? 33.556  94.759  50.491  1.00 29.42  ? 215  ILE A C     1 
ATOM   4918  O  O     . ILE C 2 215 ? 34.181  95.692  49.971  1.00 24.81  ? 215  ILE A O     1 
ATOM   4919  C  CB    . ILE C 2 215 ? 33.676  94.336  52.967  1.00 20.33  ? 215  ILE A CB    1 
ATOM   4920  C  CG1   . ILE C 2 215 ? 33.101  94.730  54.321  1.00 35.39  ? 215  ILE A CG1   1 
ATOM   4921  C  CG2   . ILE C 2 215 ? 35.094  94.793  52.826  1.00 32.64  ? 215  ILE A CG2   1 
ATOM   4922  C  CD1   . ILE C 2 215 ? 33.596  93.871  55.482  1.00 34.51  ? 215  ILE A CD1   1 
ATOM   4923  N  N     . HIS C 2 216 ? 33.456  93.565  49.909  1.00 17.50  ? 216  HIS A N     1 
ATOM   4924  C  CA    . HIS C 2 216 ? 34.095  93.292  48.617  1.00 22.85  ? 216  HIS A CA    1 
ATOM   4925  C  C     . HIS C 2 216 ? 33.471  94.028  47.424  1.00 25.63  ? 216  HIS A C     1 
ATOM   4926  O  O     . HIS C 2 216 ? 34.194  94.481  46.518  1.00 21.52  ? 216  HIS A O     1 
ATOM   4927  C  CB    . HIS C 2 216 ? 34.109  91.800  48.407  1.00 15.30  ? 216  HIS A CB    1 
ATOM   4928  C  CG    . HIS C 2 216 ? 34.739  91.080  49.550  1.00 24.06  ? 216  HIS A CG    1 
ATOM   4929  N  ND1   . HIS C 2 216 ? 34.458  89.769  49.857  1.00 33.92  ? 216  HIS A ND1   1 
ATOM   4930  C  CD2   . HIS C 2 216 ? 35.598  91.512  50.500  1.00 28.49  ? 216  HIS A CD2   1 
ATOM   4931  C  CE1   . HIS C 2 216 ? 35.110  89.430  50.954  1.00 42.16  ? 216  HIS A CE1   1 
ATOM   4932  N  NE2   . HIS C 2 216 ? 35.810  90.470  51.365  1.00 31.99  ? 216  HIS A NE2   1 
ATOM   4933  N  N     . VAL C 2 217 ? 32.144  94.162  47.427  1.00 23.24  ? 217  VAL A N     1 
ATOM   4934  C  CA    . VAL C 2 217 ? 31.448  94.909  46.377  1.00 21.14  ? 217  VAL A CA    1 
ATOM   4935  C  C     . VAL C 2 217 ? 31.981  96.347  46.338  1.00 28.12  ? 217  VAL A C     1 
ATOM   4936  O  O     . VAL C 2 217 ? 32.206  96.931  45.267  1.00 29.82  ? 217  VAL A O     1 
ATOM   4937  C  CB    . VAL C 2 217 ? 29.930  94.959  46.647  1.00 13.65  ? 217  VAL A CB    1 
ATOM   4938  C  CG1   . VAL C 2 217 ? 29.257  96.075  45.803  1.00 22.91  ? 217  VAL A CG1   1 
ATOM   4939  C  CG2   . VAL C 2 217 ? 29.320  93.606  46.263  1.00 21.40  ? 217  VAL A CG2   1 
ATOM   4940  N  N     . LEU C 2 218 ? 32.183  96.911  47.518  1.00 24.32  ? 218  LEU A N     1 
ATOM   4941  C  CA    . LEU C 2 218 ? 32.675  98.278  47.628  1.00 32.21  ? 218  LEU A CA    1 
ATOM   4942  C  C     . LEU C 2 218 ? 34.108  98.415  47.120  1.00 28.59  ? 218  LEU A C     1 
ATOM   4943  O  O     . LEU C 2 218 ? 34.432  99.387  46.437  1.00 34.08  ? 218  LEU A O     1 
ATOM   4944  C  CB    . LEU C 2 218 ? 32.578  98.750  49.088  1.00 22.11  ? 218  LEU A CB    1 
ATOM   4945  C  CG    . LEU C 2 218 ? 31.665  99.902  49.555  1.00 36.88  ? 218  LEU A CG    1 
ATOM   4946  C  CD1   . LEU C 2 218 ? 30.504  100.215 48.596  1.00 18.75  ? 218  LEU A CD1   1 
ATOM   4947  C  CD2   . LEU C 2 218 ? 31.180  99.523  50.932  1.00 21.35  ? 218  LEU A CD2   1 
ATOM   4948  N  N     . LEU C 2 219 ? 34.966  97.453  47.453  1.00 27.60  ? 219  LEU A N     1 
ATOM   4949  C  CA    . LEU C 2 219 ? 36.360  97.499  47.006  1.00 29.80  ? 219  LEU A CA    1 
ATOM   4950  C  C     . LEU C 2 219 ? 36.388  97.418  45.477  1.00 29.79  ? 219  LEU A C     1 
ATOM   4951  O  O     . LEU C 2 219 ? 37.129  98.154  44.832  1.00 30.11  ? 219  LEU A O     1 
ATOM   4952  C  CB    . LEU C 2 219 ? 37.182  96.335  47.609  1.00 31.17  ? 219  LEU A CB    1 
ATOM   4953  C  CG    . LEU C 2 219 ? 37.616  96.508  49.055  1.00 26.34  ? 219  LEU A CG    1 
ATOM   4954  C  CD1   . LEU C 2 219 ? 38.048  95.204  49.638  1.00 23.47  ? 219  LEU A CD1   1 
ATOM   4955  C  CD2   . LEU C 2 219 ? 38.740  97.508  49.117  1.00 29.47  ? 219  LEU A CD2   1 
ATOM   4956  N  N     . TYR C 2 220 ? 35.588  96.519  44.899  1.00 33.29  ? 220  TYR A N     1 
ATOM   4957  C  CA    . TYR C 2 220 ? 35.525  96.416  43.443  1.00 33.63  ? 220  TYR A CA    1 
ATOM   4958  C  C     . TYR C 2 220 ? 35.109  97.760  42.866  1.00 35.01  ? 220  TYR A C     1 
ATOM   4959  O  O     . TYR C 2 220 ? 35.660  98.217  41.855  1.00 31.83  ? 220  TYR A O     1 
ATOM   4960  C  CB    . TYR C 2 220 ? 34.542  95.337  43.005  1.00 31.43  ? 220  TYR A CB    1 
ATOM   4961  C  CG    . TYR C 2 220 ? 35.152  93.958  42.967  1.00 27.35  ? 220  TYR A CG    1 
ATOM   4962  C  CD1   . TYR C 2 220 ? 34.812  93.011  43.915  1.00 26.97  ? 220  TYR A CD1   1 
ATOM   4963  C  CD2   . TYR C 2 220 ? 36.079  93.604  41.981  1.00 24.99  ? 220  TYR A CD2   1 
ATOM   4964  C  CE1   . TYR C 2 220 ? 35.365  91.746  43.899  1.00 25.59  ? 220  TYR A CE1   1 
ATOM   4965  C  CE2   . TYR C 2 220 ? 36.644  92.331  41.953  1.00 22.50  ? 220  TYR A CE2   1 
ATOM   4966  C  CZ    . TYR C 2 220 ? 36.277  91.409  42.916  1.00 27.83  ? 220  TYR A CZ    1 
ATOM   4967  O  OH    . TYR C 2 220 ? 36.784  90.130  42.898  1.00 29.93  ? 220  TYR A OH    1 
ATOM   4968  N  N     . ARG C 2 221 ? 34.150  98.403  43.524  1.00 33.45  ? 221  ARG A N     1 
ATOM   4969  C  CA    . ARG C 2 221 ? 33.704  99.714  43.065  1.00 39.41  ? 221  ARG A CA    1 
ATOM   4970  C  C     . ARG C 2 221 ? 34.864  100.708 43.161  1.00 35.55  ? 221  ARG A C     1 
ATOM   4971  O  O     . ARG C 2 221 ? 35.172  101.413 42.201  1.00 38.81  ? 221  ARG A O     1 
ATOM   4972  C  CB    . ARG C 2 221 ? 32.540  100.252 43.915  1.00 26.79  ? 221  ARG A CB    1 
ATOM   4973  C  CG    . ARG C 2 221 ? 31.930  101.514 43.313  1.00 39.20  ? 221  ARG A CG    1 
ATOM   4974  C  CD    . ARG C 2 221 ? 31.151  102.373 44.304  1.00 36.70  ? 221  ARG A CD    1 
ATOM   4975  N  NE    . ARG C 2 221 ? 30.076  101.636 44.944  1.00 45.57  ? 221  ARG A NE    1 
ATOM   4976  C  CZ    . ARG C 2 221 ? 29.273  102.154 45.865  1.00 52.39  ? 221  ARG A CZ    1 
ATOM   4977  N  NH1   . ARG C 2 221 ? 29.429  103.422 46.245  1.00 45.11  ? 221  ARG A NH1   1 
ATOM   4978  N  NH2   . ARG C 2 221 ? 28.335  101.395 46.415  1.00 52.02  ? 221  ARG A NH2   1 
ATOM   4979  N  N     . ALA C 2 222 ? 35.491  100.752 44.332  1.00 31.93  ? 222  ALA A N     1 
ATOM   4980  C  CA    . ALA C 2 222 ? 36.596  101.659 44.611  1.00 29.05  ? 222  ALA A CA    1 
ATOM   4981  C  C     . ALA C 2 222 ? 37.700  101.583 43.567  1.00 31.71  ? 222  ALA A C     1 
ATOM   4982  O  O     . ALA C 2 222 ? 38.243  102.603 43.176  1.00 35.59  ? 222  ALA A O     1 
ATOM   4983  C  CB    . ALA C 2 222 ? 37.164  101.361 45.992  1.00 26.19  ? 222  ALA A CB    1 
ATOM   4984  N  N     . PHE C 2 223 ? 38.035  100.375 43.120  1.00 32.21  ? 223  PHE A N     1 
ATOM   4985  C  CA    . PHE C 2 223 ? 39.077  100.201 42.114  1.00 33.02  ? 223  PHE A CA    1 
ATOM   4986  C  C     . PHE C 2 223 ? 38.536  100.416 40.708  1.00 34.75  ? 223  PHE A C     1 
ATOM   4987  O  O     . PHE C 2 223 ? 39.315  100.495 39.749  1.00 34.00  ? 223  PHE A O     1 
ATOM   4988  C  CB    . PHE C 2 223 ? 39.693  98.789  42.173  1.00 26.39  ? 223  PHE A CB    1 
ATOM   4989  C  CG    . PHE C 2 223 ? 40.561  98.558  43.353  1.00 27.51  ? 223  PHE A CG    1 
ATOM   4990  C  CD1   . PHE C 2 223 ? 41.686  99.340  43.562  1.00 30.19  ? 223  PHE A CD1   1 
ATOM   4991  C  CD2   . PHE C 2 223 ? 40.277  97.536  44.247  1.00 26.82  ? 223  PHE A CD2   1 
ATOM   4992  C  CE1   . PHE C 2 223 ? 42.520  99.098  44.649  1.00 29.44  ? 223  PHE A CE1   1 
ATOM   4993  C  CE2   . PHE C 2 223 ? 41.098  97.286  45.335  1.00 24.44  ? 223  PHE A CE2   1 
ATOM   4994  C  CZ    . PHE C 2 223 ? 42.222  98.063  45.539  1.00 23.35  ? 223  PHE A CZ    1 
ATOM   4995  N  N     . GLY C 2 224 ? 37.212  100.501 40.591  1.00 33.22  ? 224  GLY A N     1 
ATOM   4996  C  CA    . GLY C 2 224 ? 36.585  100.661 39.292  1.00 31.60  ? 224  GLY A CA    1 
ATOM   4997  C  C     . GLY C 2 224 ? 36.597  99.360  38.484  1.00 39.05  ? 224  GLY A C     1 
ATOM   4998  O  O     . GLY C 2 224 ? 36.741  99.390  37.260  1.00 39.38  ? 224  GLY A O     1 
ATOM   4999  N  N     . TRP C 2 225 ? 36.442  98.220  39.161  1.00 35.14  ? 225  TRP A N     1 
ATOM   5000  C  CA    . TRP C 2 225 ? 36.436  96.923  38.492  1.00 34.44  ? 225  TRP A CA    1 
ATOM   5001  C  C     . TRP C 2 225 ? 35.036  96.317  38.492  1.00 37.11  ? 225  TRP A C     1 
ATOM   5002  O  O     . TRP C 2 225 ? 34.166  96.730  39.242  1.00 39.21  ? 225  TRP A O     1 
ATOM   5003  C  CB    . TRP C 2 225 ? 37.400  95.941  39.185  1.00 28.32  ? 225  TRP A CB    1 
ATOM   5004  C  CG    . TRP C 2 225 ? 38.828  96.391  39.244  1.00 28.35  ? 225  TRP A CG    1 
ATOM   5005  C  CD1   . TRP C 2 225 ? 39.461  97.233  38.365  1.00 31.44  ? 225  TRP A CD1   1 
ATOM   5006  C  CD2   . TRP C 2 225 ? 39.833  95.954  40.168  1.00 26.81  ? 225  TRP A CD2   1 
ATOM   5007  N  NE1   . TRP C 2 225 ? 40.789  97.338  38.680  1.00 26.40  ? 225  TRP A NE1   1 
ATOM   5008  C  CE2   . TRP C 2 225 ? 41.050  96.565  39.780  1.00 27.88  ? 225  TRP A CE2   1 
ATOM   5009  C  CE3   . TRP C 2 225 ? 39.826  95.102  41.284  1.00 24.48  ? 225  TRP A CE3   1 
ATOM   5010  C  CZ2   . TRP C 2 225 ? 42.254  96.354  40.468  1.00 34.31  ? 225  TRP A CZ2   1 
ATOM   5011  C  CZ3   . TRP C 2 225 ? 41.026  94.892  41.974  1.00 28.90  ? 225  TRP A CZ3   1 
ATOM   5012  C  CH2   . TRP C 2 225 ? 42.222  95.516  41.561  1.00 35.93  ? 225  TRP A CH2   1 
ATOM   5013  N  N     . GLU C 2 226 ? 34.838  95.315  37.659  1.00 36.61  ? 226  GLU A N     1 
ATOM   5014  C  CA    . GLU C 2 226 ? 33.559  94.639  37.557  1.00 32.63  ? 226  GLU A CA    1 
ATOM   5015  C  C     . GLU C 2 226 ? 33.533  93.500  38.591  1.00 34.97  ? 226  GLU A C     1 
ATOM   5016  O  O     . GLU C 2 226 ? 34.436  92.644  38.632  1.00 26.24  ? 226  GLU A O     1 
ATOM   5017  C  CB    . GLU C 2 226 ? 33.421  94.097  36.122  1.00 39.38  ? 226  GLU A CB    1 
ATOM   5018  C  CG    . GLU C 2 226 ? 32.149  93.310  35.814  1.00 54.31  ? 226  GLU A CG    1 
ATOM   5019  C  CD    . GLU C 2 226 ? 32.224  92.532  34.478  1.00 59.91  ? 226  GLU A CD    1 
ATOM   5020  O  OE1   . GLU C 2 226 ? 33.272  91.906  34.203  1.00 65.85  ? 226  GLU A OE1   1 
ATOM   5021  O  OE2   . GLU C 2 226 ? 31.234  92.525  33.711  1.00 51.75  ? 226  GLU A OE2   1 
ATOM   5022  N  N     . ALA C 2 227 ? 32.498  93.485  39.427  1.00 28.88  ? 227  ALA A N     1 
ATOM   5023  C  CA    . ALA C 2 227 ? 32.360  92.458  40.449  1.00 27.34  ? 227  ALA A CA    1 
ATOM   5024  C  C     . ALA C 2 227 ? 32.044  91.098  39.839  1.00 27.99  ? 227  ALA A C     1 
ATOM   5025  O  O     . ALA C 2 227 ? 31.378  91.000  38.822  1.00 33.83  ? 227  ALA A O     1 
ATOM   5026  C  CB    . ALA C 2 227 ? 31.247  92.836  41.419  1.00 37.56  ? 227  ALA A CB    1 
ATOM   5027  N  N     . PRO C 2 228 ? 32.526  90.026  40.455  1.00 29.18  ? 228  PRO A N     1 
ATOM   5028  C  CA    . PRO C 2 228 ? 32.228  88.702  39.896  1.00 23.55  ? 228  PRO A CA    1 
ATOM   5029  C  C     . PRO C 2 228 ? 30.861  88.259  40.435  1.00 27.62  ? 228  PRO A C     1 
ATOM   5030  O  O     . PRO C 2 228 ? 30.219  89.003  41.201  1.00 19.72  ? 228  PRO A O     1 
ATOM   5031  C  CB    . PRO C 2 228 ? 33.365  87.828  40.458  1.00 22.77  ? 228  PRO A CB    1 
ATOM   5032  C  CG    . PRO C 2 228 ? 33.573  88.420  41.827  1.00 24.62  ? 228  PRO A CG    1 
ATOM   5033  C  CD    . PRO C 2 228 ? 33.510  89.939  41.553  1.00 29.06  ? 228  PRO A CD    1 
ATOM   5034  N  N     . ARG C 2 229 ? 30.418  87.067  40.033  1.00 18.92  ? 229  ARG A N     1 
ATOM   5035  C  CA    . ARG C 2 229 ? 29.161  86.540  40.548  1.00 21.49  ? 229  ARG A CA    1 
ATOM   5036  C  C     . ARG C 2 229 ? 29.544  85.863  41.851  1.00 28.02  ? 229  ARG A C     1 
ATOM   5037  O  O     . ARG C 2 229 ? 30.652  85.293  41.983  1.00 19.41  ? 229  ARG A O     1 
ATOM   5038  C  CB    . ARG C 2 229 ? 28.569  85.464  39.647  1.00 21.40  ? 229  ARG A CB    1 
ATOM   5039  C  CG    . ARG C 2 229 ? 28.223  85.882  38.229  1.00 32.06  ? 229  ARG A CG    1 
ATOM   5040  C  CD    . ARG C 2 229 ? 28.053  84.614  37.337  1.00 34.30  ? 229  ARG A CD    1 
ATOM   5041  N  NE    . ARG C 2 229 ? 28.095  84.998  35.929  1.00 43.45  ? 229  ARG A NE    1 
ATOM   5042  C  CZ    . ARG C 2 229 ? 29.133  84.835  35.115  1.00 42.88  ? 229  ARG A CZ    1 
ATOM   5043  N  NH1   . ARG C 2 229 ? 30.257  84.260  35.532  1.00 44.07  ? 229  ARG A NH1   1 
ATOM   5044  N  NH2   . ARG C 2 229 ? 29.066  85.322  33.884  1.00 54.53  ? 229  ARG A NH2   1 
ATOM   5045  N  N     . PHE C 2 230 ? 28.606  85.899  42.789  1.00 26.06  ? 230  PHE A N     1 
ATOM   5046  C  CA    . PHE C 2 230 ? 28.771  85.290  44.096  1.00 21.22  ? 230  PHE A CA    1 
ATOM   5047  C  C     . PHE C 2 230 ? 27.764  84.174  44.343  1.00 27.48  ? 230  PHE A C     1 
ATOM   5048  O  O     . PHE C 2 230 ? 26.569  84.346  44.085  1.00 34.96  ? 230  PHE A O     1 
ATOM   5049  C  CB    . PHE C 2 230 ? 28.610  86.353  45.171  1.00 20.92  ? 230  PHE A CB    1 
ATOM   5050  C  CG    . PHE C 2 230 ? 29.658  87.413  45.125  1.00 26.65  ? 230  PHE A CG    1 
ATOM   5051  C  CD1   . PHE C 2 230 ? 30.965  87.134  45.531  1.00 19.85  ? 230  PHE A CD1   1 
ATOM   5052  C  CD2   . PHE C 2 230 ? 29.354  88.689  44.654  1.00 23.07  ? 230  PHE A CD2   1 
ATOM   5053  C  CE1   . PHE C 2 230 ? 31.967  88.116  45.468  1.00 16.22  ? 230  PHE A CE1   1 
ATOM   5054  C  CE2   . PHE C 2 230 ? 30.339  89.670  44.587  1.00 25.33  ? 230  PHE A CE2   1 
ATOM   5055  C  CZ    . PHE C 2 230 ? 31.654  89.387  44.995  1.00 24.73  ? 230  PHE A CZ    1 
ATOM   5056  N  N     . TYR C 2 231 ? 28.247  83.032  44.826  1.00 25.23  ? 231  TYR A N     1 
ATOM   5057  C  CA    . TYR C 2 231 ? 27.384  81.903  45.160  1.00 26.16  ? 231  TYR A CA    1 
ATOM   5058  C  C     . TYR C 2 231 ? 27.841  81.429  46.524  1.00 29.65  ? 231  TYR A C     1 
ATOM   5059  O  O     . TYR C 2 231 ? 28.957  80.945  46.678  1.00 31.80  ? 231  TYR A O     1 
ATOM   5060  C  CB    . TYR C 2 231 ? 27.526  80.712  44.203  1.00 26.17  ? 231  TYR A CB    1 
ATOM   5061  C  CG    . TYR C 2 231 ? 27.377  80.991  42.723  1.00 30.59  ? 231  TYR A CG    1 
ATOM   5062  C  CD1   . TYR C 2 231 ? 28.383  81.650  42.021  1.00 26.96  ? 231  TYR A CD1   1 
ATOM   5063  C  CD2   . TYR C 2 231 ? 26.264  80.547  42.015  1.00 27.55  ? 231  TYR A CD2   1 
ATOM   5064  C  CE1   . TYR C 2 231 ? 28.295  81.856  40.652  1.00 27.56  ? 231  TYR A CE1   1 
ATOM   5065  C  CE2   . TYR C 2 231 ? 26.156  80.751  40.638  1.00 30.01  ? 231  TYR A CE2   1 
ATOM   5066  C  CZ    . TYR C 2 231 ? 27.184  81.405  39.966  1.00 33.61  ? 231  TYR A CZ    1 
ATOM   5067  O  OH    . TYR C 2 231 ? 27.142  81.602  38.612  1.00 36.47  ? 231  TYR A OH    1 
ATOM   5068  N  N     . HIS C 2 232 ? 26.987  81.562  47.525  1.00 27.73  ? 232  HIS A N     1 
ATOM   5069  C  CA    . HIS C 2 232 ? 27.369  81.120  48.845  1.00 17.14  ? 232  HIS A CA    1 
ATOM   5070  C  C     . HIS C 2 232 ? 26.734  79.785  49.197  1.00 21.47  ? 232  HIS A C     1 
ATOM   5071  O  O     . HIS C 2 232 ? 25.516  79.610  49.151  1.00 26.10  ? 232  HIS A O     1 
ATOM   5072  C  CB    . HIS C 2 232 ? 27.041  82.214  49.855  1.00 20.50  ? 232  HIS A CB    1 
ATOM   5073  C  CG    . HIS C 2 232 ? 27.925  83.418  49.715  1.00 24.26  ? 232  HIS A CG    1 
ATOM   5074  N  ND1   . HIS C 2 232 ? 27.664  84.434  48.827  1.00 29.22  ? 232  HIS A ND1   1 
ATOM   5075  C  CD2   . HIS C 2 232 ? 29.128  83.708  50.271  1.00 23.98  ? 232  HIS A CD2   1 
ATOM   5076  C  CE1   . HIS C 2 232 ? 28.665  85.297  48.834  1.00 18.94  ? 232  HIS A CE1   1 
ATOM   5077  N  NE2   . HIS C 2 232 ? 29.565  84.877  49.700  1.00 26.50  ? 232  HIS A NE2   1 
ATOM   5078  N  N     . MET C 2 233 ? 27.591  78.814  49.470  1.00 21.49  ? 233  MET A N     1 
ATOM   5079  C  CA    . MET C 2 233 ? 27.152  77.481  49.820  1.00 23.73  ? 233  MET A CA    1 
ATOM   5080  C  C     . MET C 2 233 ? 26.889  77.395  51.330  1.00 34.49  ? 233  MET A C     1 
ATOM   5081  O  O     . MET C 2 233 ? 27.584  78.014  52.149  1.00 37.73  ? 233  MET A O     1 
ATOM   5082  C  CB    . MET C 2 233 ? 28.228  76.445  49.492  1.00 20.92  ? 233  MET A CB    1 
ATOM   5083  C  CG    . MET C 2 233 ? 28.661  76.312  48.041  1.00 28.52  ? 233  MET A CG    1 
ATOM   5084  S  SD    . MET C 2 233 ? 27.368  75.726  46.999  1.00 41.33  ? 233  MET A SD    1 
ATOM   5085  C  CE    . MET C 2 233 ? 27.084  74.073  47.611  1.00 33.10  ? 233  MET A CE    1 
ATOM   5086  N  N     . PRO C 2 234 ? 25.903  76.590  51.718  1.00 34.39  ? 234  PRO A N     1 
ATOM   5087  C  CA    . PRO C 2 234 ? 25.599  76.446  53.143  1.00 40.27  ? 234  PRO A CA    1 
ATOM   5088  C  C     . PRO C 2 234 ? 26.774  75.776  53.886  1.00 35.75  ? 234  PRO A C     1 
ATOM   5089  O  O     . PRO C 2 234 ? 27.509  74.985  53.309  1.00 35.45  ? 234  PRO A O     1 
ATOM   5090  C  CB    . PRO C 2 234 ? 24.316  75.602  53.133  1.00 40.27  ? 234  PRO A CB    1 
ATOM   5091  C  CG    . PRO C 2 234 ? 24.469  74.769  51.873  1.00 40.99  ? 234  PRO A CG    1 
ATOM   5092  C  CD    . PRO C 2 234 ? 25.022  75.752  50.880  1.00 34.23  ? 234  PRO A CD    1 
ATOM   5093  N  N     . LEU C 2 235 ? 26.966  76.119  55.153  1.00 36.62  ? 235  LEU A N     1 
ATOM   5094  C  CA    . LEU C 2 235 ? 28.051  75.529  55.913  1.00 38.64  ? 235  LEU A CA    1 
ATOM   5095  C  C     . LEU C 2 235 ? 27.734  74.098  56.273  1.00 39.53  ? 235  LEU A C     1 
ATOM   5096  O  O     . LEU C 2 235 ? 26.581  73.753  56.500  1.00 37.13  ? 235  LEU A O     1 
ATOM   5097  C  CB    . LEU C 2 235 ? 28.302  76.278  57.223  1.00 47.64  ? 235  LEU A CB    1 
ATOM   5098  C  CG    . LEU C 2 235 ? 29.265  77.455  57.284  1.00 45.97  ? 235  LEU A CG    1 
ATOM   5099  C  CD1   . LEU C 2 235 ? 30.640  77.032  56.797  1.00 40.07  ? 235  LEU A CD1   1 
ATOM   5100  C  CD2   . LEU C 2 235 ? 28.718  78.563  56.439  1.00 64.69  ? 235  LEU A CD2   1 
ATOM   5101  N  N     . LEU C 2 236 ? 28.778  73.278  56.308  1.00 34.51  ? 236  LEU A N     1 
ATOM   5102  C  CA    . LEU C 2 236 ? 28.685  71.882  56.705  1.00 31.99  ? 236  LEU A CA    1 
ATOM   5103  C  C     . LEU C 2 236 ? 28.477  72.006  58.233  1.00 32.93  ? 236  LEU A C     1 
ATOM   5104  O  O     . LEU C 2 236 ? 29.092  72.862  58.884  1.00 34.82  ? 236  LEU A O     1 
ATOM   5105  C  CB    . LEU C 2 236 ? 30.012  71.179  56.385  1.00 26.20  ? 236  LEU A CB    1 
ATOM   5106  C  CG    . LEU C 2 236 ? 30.159  70.210  55.207  1.00 32.85  ? 236  LEU A CG    1 
ATOM   5107  C  CD1   . LEU C 2 236 ? 29.365  70.632  54.009  1.00 22.51  ? 236  LEU A CD1   1 
ATOM   5108  C  CD2   . LEU C 2 236 ? 31.633  70.084  54.889  1.00 23.95  ? 236  LEU A CD2   1 
ATOM   5109  N  N     . ARG C 2 237 ? 27.641  71.154  58.811  1.00 26.99  ? 237  ARG A N     1 
ATOM   5110  C  CA    . ARG C 2 237 ? 27.354  71.260  60.234  1.00 24.50  ? 237  ARG A CA    1 
ATOM   5111  C  C     . ARG C 2 237 ? 27.690  70.053  61.090  1.00 29.01  ? 237  ARG A C     1 
ATOM   5112  O  O     . ARG C 2 237 ? 27.678  68.914  60.617  1.00 19.15  ? 237  ARG A O     1 
ATOM   5113  C  CB    . ARG C 2 237 ? 25.854  71.552  60.445  1.00 28.49  ? 237  ARG A CB    1 
ATOM   5114  C  CG    . ARG C 2 237 ? 25.263  72.652  59.557  1.00 30.88  ? 237  ARG A CG    1 
ATOM   5115  C  CD    . ARG C 2 237 ? 26.065  73.983  59.623  1.00 24.84  ? 237  ARG A CD    1 
ATOM   5116  N  NE    . ARG C 2 237 ? 25.314  75.021  58.932  1.00 36.90  ? 237  ARG A NE    1 
ATOM   5117  C  CZ    . ARG C 2 237 ? 24.128  75.460  59.352  1.00 39.94  ? 237  ARG A CZ    1 
ATOM   5118  N  NH1   . ARG C 2 237 ? 23.593  74.960  60.459  1.00 30.06  ? 237  ARG A NH1   1 
ATOM   5119  N  NH2   . ARG C 2 237 ? 23.456  76.360  58.655  1.00 36.85  ? 237  ARG A NH2   1 
ATOM   5120  N  N     . ASN C 2 238 ? 27.947  70.339  62.371  1.00 34.56  ? 238  ASN A N     1 
ATOM   5121  C  CA    . ASN C 2 238 ? 28.211  69.331  63.389  1.00 29.12  ? 238  ASN A CA    1 
ATOM   5122  C  C     . ASN C 2 238 ? 26.825  68.743  63.626  1.00 29.37  ? 238  ASN A C     1 
ATOM   5123  O  O     . ASN C 2 238 ? 25.830  69.267  63.152  1.00 30.37  ? 238  ASN A O     1 
ATOM   5124  C  CB    . ASN C 2 238 ? 28.680  69.968  64.695  1.00 32.86  ? 238  ASN A CB    1 
ATOM   5125  C  CG    . ASN C 2 238 ? 30.000  70.686  64.564  1.00 46.42  ? 238  ASN A CG    1 
ATOM   5126  O  OD1   . ASN C 2 238 ? 31.014  70.095  64.187  1.00 52.96  ? 238  ASN A OD1   1 
ATOM   5127  N  ND2   . ASN C 2 238 ? 30.003  71.967  64.893  1.00 46.74  ? 238  ASN A ND2   1 
ATOM   5128  N  N     . PRO C 2 239 ? 26.746  67.642  64.362  1.00 35.81  ? 239  PRO A N     1 
ATOM   5129  C  CA    . PRO C 2 239 ? 25.416  67.067  64.598  1.00 37.46  ? 239  PRO A CA    1 
ATOM   5130  C  C     . PRO C 2 239 ? 24.450  68.034  65.303  1.00 42.38  ? 239  PRO A C     1 
ATOM   5131  O  O     . PRO C 2 239 ? 23.239  67.944  65.107  1.00 41.92  ? 239  PRO A O     1 
ATOM   5132  C  CB    . PRO C 2 239 ? 25.723  65.822  65.428  1.00 41.37  ? 239  PRO A CB    1 
ATOM   5133  C  CG    . PRO C 2 239 ? 27.122  65.411  64.918  1.00 45.78  ? 239  PRO A CG    1 
ATOM   5134  C  CD    . PRO C 2 239 ? 27.829  66.758  64.843  1.00 31.98  ? 239  PRO A CD    1 
ATOM   5135  N  N     . ASP C 2 240 ? 24.965  68.964  66.112  1.00 38.53  ? 240  ASP A N     1 
ATOM   5136  C  CA    . ASP C 2 240 ? 24.064  69.910  66.790  1.00 44.08  ? 240  ASP A CA    1 
ATOM   5137  C  C     . ASP C 2 240 ? 23.646  71.082  65.918  1.00 41.16  ? 240  ASP A C     1 
ATOM   5138  O  O     . ASP C 2 240 ? 23.042  72.032  66.413  1.00 41.02  ? 240  ASP A O     1 
ATOM   5139  C  CB    . ASP C 2 240 ? 24.682  70.468  68.082  1.00 36.13  ? 240  ASP A CB    1 
ATOM   5140  C  CG    . ASP C 2 240 ? 25.933  71.285  67.826  1.00 49.72  ? 240  ASP A CG    1 
ATOM   5141  O  OD1   . ASP C 2 240 ? 26.183  71.627  66.641  1.00 44.88  ? 240  ASP A OD1   1 
ATOM   5142  O  OD2   . ASP C 2 240 ? 26.660  71.586  68.813  1.00 38.39  ? 240  ASP A OD2   1 
ATOM   5143  N  N     . LYS C 2 241 ? 23.974  71.007  64.629  1.00 37.65  ? 241  LYS A N     1 
ATOM   5144  C  CA    . LYS C 2 241 ? 23.643  72.040  63.637  1.00 41.82  ? 241  LYS A CA    1 
ATOM   5145  C  C     . LYS C 2 241 ? 24.582  73.254  63.616  1.00 37.41  ? 241  LYS A C     1 
ATOM   5146  O  O     . LYS C 2 241 ? 24.398  74.154  62.815  1.00 40.06  ? 241  LYS A O     1 
ATOM   5147  C  CB    . LYS C 2 241 ? 22.198  72.533  63.810  1.00 44.62  ? 241  LYS A CB    1 
ATOM   5148  C  CG    . LYS C 2 241 ? 21.146  71.429  63.824  1.00 50.37  ? 241  LYS A CG    1 
ATOM   5149  C  CD    . LYS C 2 241 ? 20.864  70.909  62.432  1.00 56.80  ? 241  LYS A CD    1 
ATOM   5150  C  CE    . LYS C 2 241 ? 19.503  70.196  62.360  1.00 58.50  ? 241  LYS A CE    1 
ATOM   5151  N  NZ    . LYS C 2 241 ? 19.540  68.762  62.762  1.00 61.92  ? 241  LYS A NZ    1 
ATOM   5152  N  N     . THR C 2 242 ? 25.568  73.302  64.498  1.00 29.37  ? 242  THR A N     1 
ATOM   5153  C  CA    . THR C 2 242 ? 26.491  74.410  64.462  1.00 32.19  ? 242  THR A CA    1 
ATOM   5154  C  C     . THR C 2 242 ? 27.504  74.099  63.350  1.00 31.60  ? 242  THR A C     1 
ATOM   5155  O  O     . THR C 2 242 ? 27.637  72.950  62.939  1.00 29.38  ? 242  THR A O     1 
ATOM   5156  C  CB    . THR C 2 242 ? 27.210  74.589  65.808  1.00 32.65  ? 242  THR A CB    1 
ATOM   5157  O  OG1   . THR C 2 242 ? 27.819  73.350  66.203  1.00 31.81  ? 242  THR A OG1   1 
ATOM   5158  C  CG2   . THR C 2 242 ? 26.209  75.066  66.874  1.00 32.86  ? 242  THR A CG2   1 
ATOM   5159  N  N     . LYS C 2 243 ? 28.221  75.106  62.865  1.00 28.19  ? 243  LYS A N     1 
ATOM   5160  C  CA    . LYS C 2 243 ? 29.162  74.845  61.801  1.00 28.05  ? 243  LYS A CA    1 
ATOM   5161  C  C     . LYS C 2 243 ? 30.169  73.816  62.248  1.00 29.23  ? 243  LYS A C     1 
ATOM   5162  O  O     . LYS C 2 243 ? 30.737  73.903  63.329  1.00 28.20  ? 243  LYS A O     1 
ATOM   5163  C  CB    . LYS C 2 243 ? 29.847  76.124  61.311  1.00 32.44  ? 243  LYS A CB    1 
ATOM   5164  C  CG    . LYS C 2 243 ? 30.882  76.734  62.202  1.00 39.44  ? 243  LYS A CG    1 
ATOM   5165  C  CD    . LYS C 2 243 ? 31.702  77.727  61.376  1.00 46.95  ? 243  LYS A CD    1 
ATOM   5166  C  CE    . LYS C 2 243 ? 32.647  78.562  62.227  1.00 49.94  ? 243  LYS A CE    1 
ATOM   5167  N  NZ    . LYS C 2 243 ? 33.452  79.470  61.366  1.00 59.22  ? 243  LYS A NZ    1 
ATOM   5168  N  N     . ILE C 2 244 ? 30.337  72.815  61.399  1.00 25.88  ? 244  ILE A N     1 
ATOM   5169  C  CA    . ILE C 2 244 ? 31.219  71.708  61.664  1.00 25.95  ? 244  ILE A CA    1 
ATOM   5170  C  C     . ILE C 2 244 ? 32.503  72.227  62.314  1.00 26.68  ? 244  ILE A C     1 
ATOM   5171  O  O     . ILE C 2 244 ? 33.091  73.200  61.854  1.00 24.04  ? 244  ILE A O     1 
ATOM   5172  C  CB    . ILE C 2 244 ? 31.460  70.947  60.337  1.00 30.62  ? 244  ILE A CB    1 
ATOM   5173  C  CG1   . ILE C 2 244 ? 32.009  69.564  60.626  1.00 26.10  ? 244  ILE A CG1   1 
ATOM   5174  C  CG2   . ILE C 2 244 ? 32.387  71.749  59.407  1.00 26.37  ? 244  ILE A CG2   1 
ATOM   5175  C  CD1   . ILE C 2 244 ? 31.813  68.630  59.465  1.00 31.74  ? 244  ILE A CD1   1 
ATOM   5176  N  N     . SER C 2 245 ? 32.911  71.606  63.411  1.00 22.15  ? 245  SER A N     1 
ATOM   5177  C  CA    . SER C 2 245 ? 34.112  72.059  64.099  1.00 36.37  ? 245  SER A CA    1 
ATOM   5178  C  C     . SER C 2 245 ? 34.898  70.872  64.608  1.00 38.73  ? 245  SER A C     1 
ATOM   5179  O  O     . SER C 2 245 ? 34.335  69.798  64.818  1.00 33.79  ? 245  SER A O     1 
ATOM   5180  C  CB    . SER C 2 245 ? 33.757  72.975  65.274  1.00 31.27  ? 245  SER A CB    1 
ATOM   5181  O  OG    . SER C 2 245 ? 32.921  72.297  66.193  1.00 49.35  ? 245  SER A OG    1 
ATOM   5182  N  N     . LYS C 2 246 ? 36.195  71.090  64.808  1.00 43.26  ? 246  LYS A N     1 
ATOM   5183  C  CA    . LYS C 2 246 ? 37.120  70.052  65.266  1.00 56.32  ? 246  LYS A CA    1 
ATOM   5184  C  C     . LYS C 2 246 ? 36.748  69.309  66.556  1.00 54.17  ? 246  LYS A C     1 
ATOM   5185  O  O     . LYS C 2 246 ? 37.165  68.170  66.749  1.00 54.84  ? 246  LYS A O     1 
ATOM   5186  C  CB    . LYS C 2 246 ? 38.530  70.646  65.417  1.00 55.51  ? 246  LYS A CB    1 
ATOM   5187  C  CG    . LYS C 2 246 ? 39.560  69.612  65.776  1.00 74.26  ? 246  LYS A CG    1 
ATOM   5188  C  CD    . LYS C 2 246 ? 40.920  70.208  66.087  1.00 84.21  ? 246  LYS A CD    1 
ATOM   5189  C  CE    . LYS C 2 246 ? 41.899  69.108  66.539  1.00 88.69  ? 246  LYS A CE    1 
ATOM   5190  N  NZ    . LYS C 2 246 ? 41.385  68.313  67.709  1.00 82.63  ? 246  LYS A NZ    1 
ATOM   5191  N  N     . ARG C 2 247 ? 35.980  69.940  67.442  1.00 60.45  ? 247  ARG A N     1 
ATOM   5192  C  CA    . ARG C 2 247 ? 35.604  69.281  68.689  1.00 58.55  ? 247  ARG A CA    1 
ATOM   5193  C  C     . ARG C 2 247 ? 34.304  68.489  68.701  1.00 55.56  ? 247  ARG A C     1 
ATOM   5194  O  O     . ARG C 2 247 ? 34.120  67.634  69.570  1.00 56.06  ? 247  ARG A O     1 
ATOM   5195  C  CB    . ARG C 2 247 ? 35.590  70.284  69.847  1.00 75.67  ? 247  ARG A CB    1 
ATOM   5196  C  CG    . ARG C 2 247 ? 36.863  70.221  70.712  1.00 94.16  ? 247  ARG A CG    1 
ATOM   5197  C  CD    . ARG C 2 247 ? 37.191  68.758  71.128  1.00 103.94 ? 247  ARG A CD    1 
ATOM   5198  N  NE    . ARG C 2 247 ? 38.377  68.635  71.985  1.00 105.71 ? 247  ARG A NE    1 
ATOM   5199  C  CZ    . ARG C 2 247 ? 38.886  67.477  72.408  1.00 105.25 ? 247  ARG A CZ    1 
ATOM   5200  N  NH1   . ARG C 2 247 ? 38.317  66.332  72.051  1.00 105.10 ? 247  ARG A NH1   1 
ATOM   5201  N  NH2   . ARG C 2 247 ? 39.961  67.460  73.191  1.00 99.46  ? 247  ARG A NH2   1 
ATOM   5202  N  N     . LYS C 2 248 ? 33.409  68.754  67.752  1.00 44.05  ? 248  LYS A N     1 
ATOM   5203  C  CA    . LYS C 2 248 ? 32.136  68.039  67.694  1.00 37.86  ? 248  LYS A CA    1 
ATOM   5204  C  C     . LYS C 2 248 ? 32.092  67.078  66.530  1.00 40.16  ? 248  LYS A C     1 
ATOM   5205  O  O     . LYS C 2 248 ? 31.184  66.223  66.438  1.00 42.98  ? 248  LYS A O     1 
ATOM   5206  C  CB    . LYS C 2 248 ? 30.971  69.024  67.580  1.00 34.89  ? 248  LYS A CB    1 
ATOM   5207  C  CG    . LYS C 2 248 ? 30.976  70.084  68.677  1.00 45.78  ? 248  LYS A CG    1 
ATOM   5208  C  CD    . LYS C 2 248 ? 29.730  70.940  68.629  1.00 50.70  ? 248  LYS A CD    1 
ATOM   5209  C  CE    . LYS C 2 248 ? 29.773  72.015  69.690  1.00 40.59  ? 248  LYS A CE    1 
ATOM   5210  N  NZ    . LYS C 2 248 ? 28.573  72.882  69.536  1.00 41.00  ? 248  LYS A NZ    1 
ATOM   5211  N  N     . SER C 2 249 ? 33.073  67.221  65.637  1.00 39.40  ? 249  SER A N     1 
ATOM   5212  C  CA    . SER C 2 249 ? 33.174  66.367  64.451  1.00 38.07  ? 249  SER A CA    1 
ATOM   5213  C  C     . SER C 2 249 ? 34.606  66.209  64.011  1.00 37.29  ? 249  SER A C     1 
ATOM   5214  O  O     . SER C 2 249 ? 35.500  66.875  64.522  1.00 44.38  ? 249  SER A O     1 
ATOM   5215  C  CB    . SER C 2 249 ? 32.392  66.946  63.265  1.00 32.35  ? 249  SER A CB    1 
ATOM   5216  O  OG    . SER C 2 249 ? 31.004  67.051  63.524  1.00 29.68  ? 249  SER A OG    1 
ATOM   5217  N  N     . HIS C 2 250 ? 34.801  65.309  63.048  1.00 41.92  ? 250  HIS A N     1 
ATOM   5218  C  CA    . HIS C 2 250 ? 36.104  65.057  62.442  1.00 38.95  ? 250  HIS A CA    1 
ATOM   5219  C  C     . HIS C 2 250 ? 36.200  65.965  61.216  1.00 36.61  ? 250  HIS A C     1 
ATOM   5220  O  O     . HIS C 2 250 ? 35.528  65.724  60.224  1.00 39.30  ? 250  HIS A O     1 
ATOM   5221  C  CB    . HIS C 2 250 ? 36.194  63.606  62.002  1.00 39.19  ? 250  HIS A CB    1 
ATOM   5222  C  CG    . HIS C 2 250 ? 36.320  62.645  63.136  1.00 42.69  ? 250  HIS A CG    1 
ATOM   5223  N  ND1   . HIS C 2 250 ? 37.382  62.675  64.021  1.00 43.23  ? 250  HIS A ND1   1 
ATOM   5224  C  CD2   . HIS C 2 250 ? 35.520  61.630  63.536  1.00 38.72  ? 250  HIS A CD2   1 
ATOM   5225  C  CE1   . HIS C 2 250 ? 37.227  61.717  64.916  1.00 42.83  ? 250  HIS A CE1   1 
ATOM   5226  N  NE2   . HIS C 2 250 ? 36.107  61.068  64.643  1.00 43.90  ? 250  HIS A NE2   1 
ATOM   5227  N  N     . THR C 2 251 ? 37.011  67.017  61.280  1.00 35.81  ? 251  THR A N     1 
ATOM   5228  C  CA    . THR C 2 251 ? 37.099  67.907  60.138  1.00 34.47  ? 251  THR A CA    1 
ATOM   5229  C  C     . THR C 2 251 ? 38.386  67.779  59.348  1.00 35.14  ? 251  THR A C     1 
ATOM   5230  O  O     . THR C 2 251 ? 38.547  68.465  58.342  1.00 36.72  ? 251  THR A O     1 
ATOM   5231  C  CB    . THR C 2 251 ? 36.935  69.383  60.556  1.00 38.06  ? 251  THR A CB    1 
ATOM   5232  O  OG1   . THR C 2 251 ? 37.911  69.702  61.538  1.00 32.72  ? 251  THR A OG1   1 
ATOM   5233  C  CG2   . THR C 2 251 ? 35.574  69.626  61.133  1.00 23.45  ? 251  THR A CG2   1 
ATOM   5234  N  N     . SER C 2 252 ? 39.297  66.905  59.782  1.00 36.19  ? 252  SER A N     1 
ATOM   5235  C  CA    . SER C 2 252 ? 40.570  66.721  59.078  1.00 29.77  ? 252  SER A CA    1 
ATOM   5236  C  C     . SER C 2 252 ? 40.517  65.660  57.971  1.00 25.89  ? 252  SER A C     1 
ATOM   5237  O  O     . SER C 2 252 ? 40.127  64.528  58.199  1.00 23.61  ? 252  SER A O     1 
ATOM   5238  C  CB    . SER C 2 252 ? 41.679  66.362  60.082  1.00 35.78  ? 252  SER A CB    1 
ATOM   5239  O  OG    . SER C 2 252 ? 42.949  66.256  59.460  1.00 38.79  ? 252  SER A OG    1 
ATOM   5240  N  N     . LEU C 2 253 ? 40.907  66.041  56.764  1.00 24.89  ? 253  LEU A N     1 
ATOM   5241  C  CA    . LEU C 2 253 ? 40.930  65.097  55.661  1.00 22.48  ? 253  LEU A CA    1 
ATOM   5242  C  C     . LEU C 2 253 ? 41.933  64.007  55.954  1.00 25.06  ? 253  LEU A C     1 
ATOM   5243  O  O     . LEU C 2 253 ? 41.790  62.888  55.478  1.00 30.43  ? 253  LEU A O     1 
ATOM   5244  C  CB    . LEU C 2 253 ? 41.301  65.801  54.364  1.00 20.56  ? 253  LEU A CB    1 
ATOM   5245  C  CG    . LEU C 2 253 ? 40.245  66.845  54.000  1.00 27.45  ? 253  LEU A CG    1 
ATOM   5246  C  CD1   . LEU C 2 253 ? 40.710  67.724  52.845  1.00 24.55  ? 253  LEU A CD1   1 
ATOM   5247  C  CD2   . LEU C 2 253 ? 38.947  66.108  53.649  1.00 18.51  ? 253  LEU A CD2   1 
ATOM   5248  N  N     . ASP C 2 254 ? 42.952  64.329  56.737  1.00 25.88  ? 254  ASP A N     1 
ATOM   5249  C  CA    . ASP C 2 254 ? 43.961  63.339  57.075  1.00 34.26  ? 254  ASP A CA    1 
ATOM   5250  C  C     . ASP C 2 254 ? 43.361  62.271  57.964  1.00 32.05  ? 254  ASP A C     1 
ATOM   5251  O  O     . ASP C 2 254 ? 43.745  61.109  57.867  1.00 33.14  ? 254  ASP A O     1 
ATOM   5252  C  CB    . ASP C 2 254 ? 45.167  63.995  57.755  1.00 33.88  ? 254  ASP A CB    1 
ATOM   5253  C  CG    . ASP C 2 254 ? 45.991  64.831  56.781  1.00 51.29  ? 254  ASP A CG    1 
ATOM   5254  O  OD1   . ASP C 2 254 ? 46.806  65.661  57.249  1.00 61.56  ? 254  ASP A OD1   1 
ATOM   5255  O  OD2   . ASP C 2 254 ? 45.827  64.652  55.543  1.00 49.91  ? 254  ASP A OD2   1 
ATOM   5256  N  N     . TRP C 2 255 ? 42.408  62.654  58.810  1.00 28.29  ? 255  TRP A N     1 
ATOM   5257  C  CA    . TRP C 2 255 ? 41.771  61.677  59.674  1.00 26.45  ? 255  TRP A CA    1 
ATOM   5258  C  C     . TRP C 2 255 ? 41.006  60.676  58.778  1.00 29.80  ? 255  TRP A C     1 
ATOM   5259  O  O     . TRP C 2 255 ? 41.177  59.469  58.889  1.00 34.66  ? 255  TRP A O     1 
ATOM   5260  C  CB    . TRP C 2 255 ? 40.812  62.357  60.649  1.00 26.53  ? 255  TRP A CB    1 
ATOM   5261  C  CG    . TRP C 2 255 ? 40.169  61.379  61.569  1.00 35.07  ? 255  TRP A CG    1 
ATOM   5262  C  CD1   . TRP C 2 255 ? 40.722  60.821  62.694  1.00 37.22  ? 255  TRP A CD1   1 
ATOM   5263  C  CD2   . TRP C 2 255 ? 38.910  60.719  61.374  1.00 32.64  ? 255  TRP A CD2   1 
ATOM   5264  N  NE1   . TRP C 2 255 ? 39.889  59.846  63.201  1.00 34.05  ? 255  TRP A NE1   1 
ATOM   5265  C  CE2   . TRP C 2 255 ? 38.771  59.763  62.416  1.00 40.79  ? 255  TRP A CE2   1 
ATOM   5266  C  CE3   . TRP C 2 255 ? 37.892  60.834  60.422  1.00 26.92  ? 255  TRP A CE3   1 
ATOM   5267  C  CZ2   . TRP C 2 255 ? 37.649  58.930  62.529  1.00 34.69  ? 255  TRP A CZ2   1 
ATOM   5268  C  CZ3   . TRP C 2 255 ? 36.777  60.009  60.532  1.00 40.29  ? 255  TRP A CZ3   1 
ATOM   5269  C  CH2   . TRP C 2 255 ? 36.667  59.067  61.583  1.00 45.24  ? 255  TRP A CH2   1 
ATOM   5270  N  N     . TYR C 2 256 ? 40.192  61.182  57.861  1.00 29.03  ? 256  TYR A N     1 
ATOM   5271  C  CA    . TYR C 2 256 ? 39.430  60.316  56.975  1.00 28.26  ? 256  TYR A CA    1 
ATOM   5272  C  C     . TYR C 2 256 ? 40.269  59.310  56.174  1.00 30.21  ? 256  TYR A C     1 
ATOM   5273  O  O     . TYR C 2 256 ? 39.884  58.145  56.010  1.00 30.25  ? 256  TYR A O     1 
ATOM   5274  C  CB    . TYR C 2 256 ? 38.586  61.168  56.033  1.00 27.19  ? 256  TYR A CB    1 
ATOM   5275  C  CG    . TYR C 2 256 ? 37.436  61.831  56.752  1.00 35.17  ? 256  TYR A CG    1 
ATOM   5276  C  CD1   . TYR C 2 256 ? 37.538  63.149  57.196  1.00 27.73  ? 256  TYR A CD1   1 
ATOM   5277  C  CD2   . TYR C 2 256 ? 36.282  61.120  57.065  1.00 27.55  ? 256  TYR A CD2   1 
ATOM   5278  C  CE1   . TYR C 2 256 ? 36.536  63.738  57.932  1.00 22.47  ? 256  TYR A CE1   1 
ATOM   5279  C  CE2   . TYR C 2 256 ? 35.255  61.711  57.812  1.00 29.65  ? 256  TYR A CE2   1 
ATOM   5280  C  CZ    . TYR C 2 256 ? 35.398  63.018  58.243  1.00 31.47  ? 256  TYR A CZ    1 
ATOM   5281  O  OH    . TYR C 2 256 ? 34.432  63.605  59.031  1.00 30.86  ? 256  TYR A OH    1 
ATOM   5282  N  N     . LYS C 2 257 ? 41.412  59.768  55.674  1.00 31.27  ? 257  LYS A N     1 
ATOM   5283  C  CA    . LYS C 2 257 ? 42.300  58.922  54.896  1.00 25.76  ? 257  LYS A CA    1 
ATOM   5284  C  C     . LYS C 2 257 ? 42.916  57.903  55.842  1.00 35.74  ? 257  LYS A C     1 
ATOM   5285  O  O     . LYS C 2 257 ? 42.981  56.724  55.512  1.00 32.86  ? 257  LYS A O     1 
ATOM   5286  C  CB    . LYS C 2 257 ? 43.377  59.775  54.243  1.00 25.17  ? 257  LYS A CB    1 
ATOM   5287  C  CG    . LYS C 2 257 ? 44.499  59.007  53.594  1.00 26.88  ? 257  LYS A CG    1 
ATOM   5288  C  CD    . LYS C 2 257 ? 45.030  59.816  52.418  1.00 41.40  ? 257  LYS A CD    1 
ATOM   5289  C  CE    . LYS C 2 257 ? 46.504  60.136  52.537  1.00 36.92  ? 257  LYS A CE    1 
ATOM   5290  N  NZ    . LYS C 2 257 ? 47.320  58.896  52.543  1.00 40.05  ? 257  LYS A NZ    1 
ATOM   5291  N  N     . ALA C 2 258 ? 43.349  58.352  57.024  1.00 32.12  ? 258  ALA A N     1 
ATOM   5292  C  CA    . ALA C 2 258 ? 43.947  57.453  58.019  1.00 34.89  ? 258  ALA A CA    1 
ATOM   5293  C  C     . ALA C 2 258 ? 42.968  56.365  58.426  1.00 34.24  ? 258  ALA A C     1 
ATOM   5294  O  O     . ALA C 2 258 ? 43.366  55.235  58.661  1.00 38.68  ? 258  ALA A O     1 
ATOM   5295  C  CB    . ALA C 2 258 ? 44.378  58.223  59.264  1.00 25.81  ? 258  ALA A CB    1 
ATOM   5296  N  N     . GLU C 2 259 ? 41.691  56.715  58.509  1.00 28.81  ? 259  GLU A N     1 
ATOM   5297  C  CA    . GLU C 2 259 ? 40.674  55.763  58.902  1.00 27.01  ? 259  GLU A CA    1 
ATOM   5298  C  C     . GLU C 2 259 ? 40.234  54.802  57.818  1.00 31.34  ? 259  GLU A C     1 
ATOM   5299  O  O     . GLU C 2 259 ? 39.371  53.959  58.060  1.00 25.15  ? 259  GLU A O     1 
ATOM   5300  C  CB    . GLU C 2 259 ? 39.455  56.499  59.445  1.00 39.29  ? 259  GLU A CB    1 
ATOM   5301  C  CG    . GLU C 2 259 ? 39.670  57.022  60.855  1.00 42.65  ? 259  GLU A CG    1 
ATOM   5302  C  CD    . GLU C 2 259 ? 39.658  55.924  61.913  1.00 57.41  ? 259  GLU A CD    1 
ATOM   5303  O  OE1   . GLU C 2 259 ? 40.498  56.005  62.838  1.00 58.63  ? 259  GLU A OE1   1 
ATOM   5304  O  OE2   . GLU C 2 259 ? 38.811  54.999  61.829  1.00 47.04  ? 259  GLU A OE2   1 
ATOM   5305  N  N     . GLY C 2 260 ? 40.810  54.936  56.623  1.00 32.18  ? 260  GLY A N     1 
ATOM   5306  C  CA    . GLY C 2 260 ? 40.472  54.040  55.533  1.00 26.59  ? 260  GLY A CA    1 
ATOM   5307  C  C     . GLY C 2 260 ? 39.193  54.348  54.761  1.00 37.49  ? 260  GLY A C     1 
ATOM   5308  O  O     . GLY C 2 260 ? 38.495  53.424  54.333  1.00 32.91  ? 260  GLY A O     1 
ATOM   5309  N  N     . PHE C 2 261 ? 38.863  55.631  54.612  1.00 26.23  ? 261  PHE A N     1 
ATOM   5310  C  CA    . PHE C 2 261 ? 37.708  56.014  53.823  1.00 24.50  ? 261  PHE A CA    1 
ATOM   5311  C  C     . PHE C 2 261 ? 38.340  56.227  52.451  1.00 25.44  ? 261  PHE A C     1 
ATOM   5312  O  O     . PHE C 2 261 ? 39.442  56.768  52.363  1.00 28.64  ? 261  PHE A O     1 
ATOM   5313  C  CB    . PHE C 2 261 ? 37.080  57.330  54.354  1.00 23.08  ? 261  PHE A CB    1 
ATOM   5314  C  CG    . PHE C 2 261 ? 36.157  57.139  55.539  1.00 28.52  ? 261  PHE A CG    1 
ATOM   5315  C  CD1   . PHE C 2 261 ? 36.633  57.270  56.849  1.00 29.13  ? 261  PHE A CD1   1 
ATOM   5316  C  CD2   . PHE C 2 261 ? 34.813  56.782  55.347  1.00 27.09  ? 261  PHE A CD2   1 
ATOM   5317  C  CE1   . PHE C 2 261 ? 35.775  57.047  57.953  1.00 29.90  ? 261  PHE A CE1   1 
ATOM   5318  C  CE2   . PHE C 2 261 ? 33.957  56.557  56.436  1.00 22.30  ? 261  PHE A CE2   1 
ATOM   5319  C  CZ    . PHE C 2 261 ? 34.441  56.692  57.742  1.00 22.64  ? 261  PHE A CZ    1 
ATOM   5320  N  N     . LEU C 2 262 ? 37.680  55.773  51.396  1.00 23.28  ? 262  LEU A N     1 
ATOM   5321  C  CA    . LEU C 2 262 ? 38.186  55.918  50.035  1.00 22.56  ? 262  LEU A CA    1 
ATOM   5322  C  C     . LEU C 2 262 ? 37.898  57.351  49.600  1.00 28.48  ? 262  LEU A C     1 
ATOM   5323  O  O     . LEU C 2 262 ? 36.811  57.886  49.880  1.00 29.55  ? 262  LEU A O     1 
ATOM   5324  C  CB    . LEU C 2 262 ? 37.452  54.966  49.062  1.00 24.69  ? 262  LEU A CB    1 
ATOM   5325  C  CG    . LEU C 2 262 ? 37.429  53.453  49.323  1.00 31.41  ? 262  LEU A CG    1 
ATOM   5326  C  CD1   . LEU C 2 262 ? 36.229  52.793  48.666  1.00 29.06  ? 262  LEU A CD1   1 
ATOM   5327  C  CD2   . LEU C 2 262 ? 38.671  52.857  48.772  1.00 36.59  ? 262  LEU A CD2   1 
ATOM   5328  N  N     . PRO C 2 263 ? 38.855  57.998  48.905  1.00 28.32  ? 263  PRO A N     1 
ATOM   5329  C  CA    . PRO C 2 263 ? 38.599  59.386  48.459  1.00 22.63  ? 263  PRO A CA    1 
ATOM   5330  C  C     . PRO C 2 263 ? 37.371  59.503  47.568  1.00 17.38  ? 263  PRO A C     1 
ATOM   5331  O  O     . PRO C 2 263 ? 36.643  60.493  47.630  1.00 28.66  ? 263  PRO A O     1 
ATOM   5332  C  CB    . PRO C 2 263 ? 39.884  59.781  47.717  1.00 21.13  ? 263  PRO A CB    1 
ATOM   5333  C  CG    . PRO C 2 263 ? 40.514  58.432  47.313  1.00 12.83  ? 263  PRO A CG    1 
ATOM   5334  C  CD    . PRO C 2 263 ? 40.200  57.527  48.510  1.00 15.19  ? 263  PRO A CD    1 
ATOM   5335  N  N     . GLU C 2 264 ? 37.120  58.474  46.769  1.00 20.28  ? 264  GLU A N     1 
ATOM   5336  C  CA    . GLU C 2 264 ? 35.984  58.468  45.840  1.00 20.75  ? 264  GLU A CA    1 
ATOM   5337  C  C     . GLU C 2 264 ? 34.662  58.512  46.594  1.00 27.49  ? 264  GLU A C     1 
ATOM   5338  O  O     . GLU C 2 264 ? 33.706  59.181  46.185  1.00 21.02  ? 264  GLU A O     1 
ATOM   5339  C  CB    . GLU C 2 264 ? 36.008  57.201  44.976  1.00 23.33  ? 264  GLU A CB    1 
ATOM   5340  C  CG    . GLU C 2 264 ? 37.121  57.168  43.943  1.00 37.66  ? 264  GLU A CG    1 
ATOM   5341  C  CD    . GLU C 2 264 ? 38.434  56.632  44.496  1.00 40.76  ? 264  GLU A CD    1 
ATOM   5342  O  OE1   . GLU C 2 264 ? 38.525  56.439  45.728  1.00 40.22  ? 264  GLU A OE1   1 
ATOM   5343  O  OE2   . GLU C 2 264 ? 39.371  56.407  43.691  1.00 44.82  ? 264  GLU A OE2   1 
ATOM   5344  N  N     . ALA C 2 265 ? 34.612  57.771  47.696  1.00 20.99  ? 265  ALA A N     1 
ATOM   5345  C  CA    . ALA C 2 265 ? 33.406  57.714  48.498  1.00 22.16  ? 265  ALA A CA    1 
ATOM   5346  C  C     . ALA C 2 265 ? 33.231  59.042  49.249  1.00 24.05  ? 265  ALA A C     1 
ATOM   5347  O  O     . ALA C 2 265 ? 32.152  59.602  49.236  1.00 25.00  ? 265  ALA A O     1 
ATOM   5348  C  CB    . ALA C 2 265 ? 33.483  56.524  49.487  1.00 20.09  ? 265  ALA A CB    1 
ATOM   5349  N  N     . LEU C 2 266 ? 34.289  59.543  49.889  1.00 21.97  ? 266  LEU A N     1 
ATOM   5350  C  CA    . LEU C 2 266 ? 34.189  60.798  50.623  1.00 23.47  ? 266  LEU A CA    1 
ATOM   5351  C  C     . LEU C 2 266 ? 33.726  61.882  49.677  1.00 25.53  ? 266  LEU A C     1 
ATOM   5352  O  O     . LEU C 2 266 ? 32.842  62.676  50.009  1.00 34.69  ? 266  LEU A O     1 
ATOM   5353  C  CB    . LEU C 2 266 ? 35.530  61.171  51.250  1.00 16.79  ? 266  LEU A CB    1 
ATOM   5354  C  CG    . LEU C 2 266 ? 35.600  62.506  51.974  1.00 28.02  ? 266  LEU A CG    1 
ATOM   5355  C  CD1   . LEU C 2 266 ? 34.481  62.582  53.042  1.00 19.63  ? 266  LEU A CD1   1 
ATOM   5356  C  CD2   . LEU C 2 266 ? 37.029  62.675  52.577  1.00 19.98  ? 266  LEU A CD2   1 
ATOM   5357  N  N     . ARG C 2 267 ? 34.290  61.882  48.474  1.00 32.54  ? 267  ARG A N     1 
ATOM   5358  C  CA    . ARG C 2 267 ? 33.925  62.860  47.462  1.00 22.96  ? 267  ARG A CA    1 
ATOM   5359  C  C     . ARG C 2 267 ? 32.478  62.726  47.013  1.00 27.53  ? 267  ARG A C     1 
ATOM   5360  O  O     . ARG C 2 267 ? 31.791  63.738  46.769  1.00 27.59  ? 267  ARG A O     1 
ATOM   5361  C  CB    . ARG C 2 267 ? 34.840  62.728  46.252  1.00 28.12  ? 267  ARG A CB    1 
ATOM   5362  C  CG    . ARG C 2 267 ? 34.474  63.657  45.098  1.00 25.59  ? 267  ARG A CG    1 
ATOM   5363  C  CD    . ARG C 2 267 ? 34.179  62.841  43.861  1.00 39.23  ? 267  ARG A CD    1 
ATOM   5364  N  NE    . ARG C 2 267 ? 32.759  62.610  43.619  1.00 39.72  ? 267  ARG A NE    1 
ATOM   5365  C  CZ    . ARG C 2 267 ? 32.247  61.449  43.198  1.00 44.04  ? 267  ARG A CZ    1 
ATOM   5366  N  NH1   . ARG C 2 267 ? 33.030  60.396  42.987  1.00 33.63  ? 267  ARG A NH1   1 
ATOM   5367  N  NH2   . ARG C 2 267 ? 30.946  61.350  42.945  1.00 33.25  ? 267  ARG A NH2   1 
ATOM   5368  N  N     . ASN C 2 268 ? 32.015  61.484  46.888  1.00 22.33  ? 268  ASN A N     1 
ATOM   5369  C  CA    . ASN C 2 268 ? 30.641  61.239  46.466  1.00 23.08  ? 268  ASN A CA    1 
ATOM   5370  C  C     . ASN C 2 268 ? 29.702  61.710  47.588  1.00 21.41  ? 268  ASN A C     1 
ATOM   5371  O  O     . ASN C 2 268 ? 28.631  62.238  47.328  1.00 28.74  ? 268  ASN A O     1 
ATOM   5372  C  CB    . ASN C 2 268 ? 30.440  59.732  46.158  1.00 24.01  ? 268  ASN A CB    1 
ATOM   5373  C  CG    . ASN C 2 268 ? 29.048  59.392  45.539  1.00 22.03  ? 268  ASN A CG    1 
ATOM   5374  O  OD1   . ASN C 2 268 ? 28.879  58.324  44.969  1.00 26.90  ? 268  ASN A OD1   1 
ATOM   5375  N  ND2   . ASN C 2 268 ? 28.073  60.289  45.670  1.00 16.55  ? 268  ASN A ND2   1 
ATOM   5376  N  N     . TYR C 2 269 ? 30.121  61.571  48.834  1.00 22.33  ? 269  TYR A N     1 
ATOM   5377  C  CA    . TYR C 2 269 ? 29.268  61.976  49.927  1.00 22.43  ? 269  TYR A CA    1 
ATOM   5378  C  C     . TYR C 2 269 ? 29.185  63.505  50.000  1.00 28.57  ? 269  TYR A C     1 
ATOM   5379  O  O     . TYR C 2 269 ? 28.116  64.091  50.179  1.00 27.15  ? 269  TYR A O     1 
ATOM   5380  C  CB    . TYR C 2 269 ? 29.790  61.387  51.238  1.00 31.31  ? 269  TYR A CB    1 
ATOM   5381  C  CG    . TYR C 2 269 ? 28.966  61.795  52.441  1.00 38.84  ? 269  TYR A CG    1 
ATOM   5382  C  CD1   . TYR C 2 269 ? 27.650  61.359  52.583  1.00 32.45  ? 269  TYR A CD1   1 
ATOM   5383  C  CD2   . TYR C 2 269 ? 29.464  62.690  53.379  1.00 24.06  ? 269  TYR A CD2   1 
ATOM   5384  C  CE1   . TYR C 2 269 ? 26.848  61.809  53.615  1.00 30.99  ? 269  TYR A CE1   1 
ATOM   5385  C  CE2   . TYR C 2 269 ? 28.664  63.151  54.426  1.00 39.01  ? 269  TYR A CE2   1 
ATOM   5386  C  CZ    . TYR C 2 269 ? 27.352  62.708  54.533  1.00 43.37  ? 269  TYR A CZ    1 
ATOM   5387  O  OH    . TYR C 2 269 ? 26.521  63.188  55.526  1.00 38.23  ? 269  TYR A OH    1 
ATOM   5388  N  N     . LEU C 2 270 ? 30.316  64.164  49.823  1.00 25.66  ? 270  LEU A N     1 
ATOM   5389  C  CA    . LEU C 2 270 ? 30.316  65.606  49.881  1.00 15.48  ? 270  LEU A CA    1 
ATOM   5390  C  C     . LEU C 2 270 ? 29.394  66.216  48.817  1.00 24.75  ? 270  LEU A C     1 
ATOM   5391  O  O     . LEU C 2 270 ? 28.784  67.254  49.057  1.00 27.44  ? 270  LEU A O     1 
ATOM   5392  C  CB    . LEU C 2 270 ? 31.744  66.105  49.728  1.00 19.34  ? 270  LEU A CB    1 
ATOM   5393  C  CG    . LEU C 2 270 ? 32.530  66.698  50.901  1.00 27.98  ? 270  LEU A CG    1 
ATOM   5394  C  CD1   . LEU C 2 270 ? 31.994  66.367  52.276  1.00 29.29  ? 270  LEU A CD1   1 
ATOM   5395  C  CD2   . LEU C 2 270 ? 33.938  66.186  50.738  1.00 22.01  ? 270  LEU A CD2   1 
ATOM   5396  N  N     . CYS C 2 271 ? 29.291  65.591  47.646  1.00 26.78  ? 271  CYS A N     1 
ATOM   5397  C  CA    . CYS C 2 271 ? 28.416  66.105  46.595  1.00 26.46  ? 271  CYS A CA    1 
ATOM   5398  C  C     . CYS C 2 271 ? 26.978  66.130  47.072  1.00 30.86  ? 271  CYS A C     1 
ATOM   5399  O  O     . CYS C 2 271 ? 26.176  66.925  46.598  1.00 33.42  ? 271  CYS A O     1 
ATOM   5400  C  CB    . CYS C 2 271 ? 28.439  65.204  45.363  1.00 33.07  ? 271  CYS A CB    1 
ATOM   5401  S  SG    . CYS C 2 271 ? 29.954  65.161  44.443  1.00 32.75  ? 271  CYS A SG    1 
ATOM   5402  N  N     . LEU C 2 272 ? 26.650  65.209  47.973  1.00 34.34  ? 272  LEU A N     1 
ATOM   5403  C  CA    . LEU C 2 272 ? 25.295  65.092  48.488  1.00 31.42  ? 272  LEU A CA    1 
ATOM   5404  C  C     . LEU C 2 272 ? 24.995  66.123  49.567  1.00 35.78  ? 272  LEU A C     1 
ATOM   5405  O  O     . LEU C 2 272 ? 23.860  66.205  50.070  1.00 29.15  ? 272  LEU A O     1 
ATOM   5406  C  CB    . LEU C 2 272 ? 25.049  63.677  49.033  1.00 34.11  ? 272  LEU A CB    1 
ATOM   5407  C  CG    . LEU C 2 272 ? 24.233  62.666  48.214  1.00 34.19  ? 272  LEU A CG    1 
ATOM   5408  C  CD1   . LEU C 2 272 ? 24.016  63.123  46.805  1.00 35.01  ? 272  LEU A CD1   1 
ATOM   5409  C  CD2   . LEU C 2 272 ? 24.969  61.345  48.213  1.00 36.57  ? 272  LEU A CD2   1 
ATOM   5410  N  N     . MET C 2 273 ? 26.014  66.893  49.938  1.00 27.73  ? 273  MET A N     1 
ATOM   5411  C  CA    . MET C 2 273 ? 25.820  67.944  50.927  1.00 29.61  ? 273  MET A CA    1 
ATOM   5412  C  C     . MET C 2 273 ? 25.419  69.196  50.151  1.00 31.10  ? 273  MET A C     1 
ATOM   5413  O  O     . MET C 2 273 ? 26.231  70.096  49.939  1.00 39.54  ? 273  MET A O     1 
ATOM   5414  C  CB    . MET C 2 273 ? 27.107  68.229  51.702  1.00 28.84  ? 273  MET A CB    1 
ATOM   5415  C  CG    . MET C 2 273 ? 27.708  67.053  52.422  1.00 32.25  ? 273  MET A CG    1 
ATOM   5416  S  SD    . MET C 2 273 ? 26.768  66.581  53.874  1.00 36.66  ? 273  MET A SD    1 
ATOM   5417  C  CE    . MET C 2 273 ? 25.621  65.466  53.155  1.00 27.33  ? 273  MET A CE    1 
ATOM   5418  N  N     . GLY C 2 274 ? 24.176  69.249  49.695  1.00 38.14  ? 274  GLY A N     1 
ATOM   5419  C  CA    . GLY C 2 274 ? 23.741  70.430  48.979  1.00 41.82  ? 274  GLY A CA    1 
ATOM   5420  C  C     . GLY C 2 274 ? 23.326  70.197  47.550  1.00 36.83  ? 274  GLY A C     1 
ATOM   5421  O  O     . GLY C 2 274 ? 22.718  71.073  46.942  1.00 46.01  ? 274  GLY A O     1 
ATOM   5422  N  N     . PHE C 2 275 ? 23.629  69.019  47.022  1.00 31.17  ? 275  PHE A N     1 
ATOM   5423  C  CA    . PHE C 2 275 ? 23.272  68.687  45.651  1.00 28.90  ? 275  PHE A CA    1 
ATOM   5424  C  C     . PHE C 2 275 ? 22.633  67.310  45.541  1.00 33.67  ? 275  PHE A C     1 
ATOM   5425  O  O     . PHE C 2 275 ? 22.859  66.444  46.388  1.00 37.22  ? 275  PHE A O     1 
ATOM   5426  C  CB    . PHE C 2 275 ? 24.527  68.712  44.760  1.00 30.88  ? 275  PHE A CB    1 
ATOM   5427  C  CG    . PHE C 2 275 ? 24.264  68.312  43.319  1.00 25.32  ? 275  PHE A CG    1 
ATOM   5428  C  CD1   . PHE C 2 275 ? 24.501  67.005  42.889  1.00 25.36  ? 275  PHE A CD1   1 
ATOM   5429  C  CD2   . PHE C 2 275 ? 23.737  69.236  42.409  1.00 19.38  ? 275  PHE A CD2   1 
ATOM   5430  C  CE1   . PHE C 2 275 ? 24.222  66.603  41.575  1.00 26.73  ? 275  PHE A CE1   1 
ATOM   5431  C  CE2   . PHE C 2 275 ? 23.450  68.856  41.105  1.00 28.42  ? 275  PHE A CE2   1 
ATOM   5432  C  CZ    . PHE C 2 275 ? 23.695  67.528  40.682  1.00 27.41  ? 275  PHE A CZ    1 
ATOM   5433  N  N     . SER C 2 276 ? 21.843  67.107  44.493  1.00 25.82  ? 276  SER A N     1 
ATOM   5434  C  CA    . SER C 2 276 ? 21.236  65.804  44.245  1.00 35.78  ? 276  SER A CA    1 
ATOM   5435  C  C     . SER C 2 276 ? 20.978  65.580  42.756  1.00 32.98  ? 276  SER A C     1 
ATOM   5436  O  O     . SER C 2 276 ? 20.671  66.509  42.019  1.00 25.73  ? 276  SER A O     1 
ATOM   5437  C  CB    . SER C 2 276 ? 19.919  65.635  45.020  1.00 38.89  ? 276  SER A CB    1 
ATOM   5438  O  OG    . SER C 2 276 ? 18.906  66.502  44.530  1.00 56.82  ? 276  SER A OG    1 
ATOM   5439  N  N     . MET C 2 277 ? 21.124  64.335  42.323  1.00 31.96  ? 277  MET A N     1 
ATOM   5440  C  CA    . MET C 2 277 ? 20.879  63.975  40.934  1.00 42.15  ? 277  MET A CA    1 
ATOM   5441  C  C     . MET C 2 277 ? 19.373  64.042  40.676  1.00 43.75  ? 277  MET A C     1 
ATOM   5442  O  O     . MET C 2 277 ? 18.577  63.782  41.583  1.00 35.38  ? 277  MET A O     1 
ATOM   5443  C  CB    . MET C 2 277 ? 21.390  62.553  40.667  1.00 40.89  ? 277  MET A CB    1 
ATOM   5444  C  CG    . MET C 2 277 ? 22.904  62.418  40.740  1.00 39.81  ? 277  MET A CG    1 
ATOM   5445  S  SD    . MET C 2 277 ? 23.676  63.254  39.332  1.00 44.62  ? 277  MET A SD    1 
ATOM   5446  C  CE    . MET C 2 277 ? 25.356  62.755  39.555  1.00 33.04  ? 277  MET A CE    1 
ATOM   5447  N  N     . PRO C 2 278 ? 18.963  64.396  39.438  1.00 47.85  ? 278  PRO A N     1 
ATOM   5448  C  CA    . PRO C 2 278 ? 17.544  64.496  39.058  1.00 46.73  ? 278  PRO A CA    1 
ATOM   5449  C  C     . PRO C 2 278 ? 16.790  63.211  39.352  1.00 51.67  ? 278  PRO A C     1 
ATOM   5450  O  O     . PRO C 2 278 ? 15.697  63.238  39.927  1.00 53.59  ? 278  PRO A O     1 
ATOM   5451  C  CB    . PRO C 2 278 ? 17.605  64.775  37.562  1.00 51.58  ? 278  PRO A CB    1 
ATOM   5452  C  CG    . PRO C 2 278 ? 18.893  65.554  37.409  1.00 46.35  ? 278  PRO A CG    1 
ATOM   5453  C  CD    . PRO C 2 278 ? 19.835  64.778  38.312  1.00 49.45  ? 278  PRO A CD    1 
ATOM   5454  N  N     . ASP C 2 279 ? 17.404  62.091  38.969  1.00 53.81  ? 279  ASP A N     1 
ATOM   5455  C  CA    . ASP C 2 279 ? 16.824  60.761  39.143  1.00 53.67  ? 279  ASP A CA    1 
ATOM   5456  C  C     . ASP C 2 279 ? 16.999  60.200  40.536  1.00 51.92  ? 279  ASP A C     1 
ATOM   5457  O  O     . ASP C 2 279 ? 16.722  59.028  40.757  1.00 54.50  ? 279  ASP A O     1 
ATOM   5458  C  CB    . ASP C 2 279 ? 17.445  59.786  38.159  1.00 57.52  ? 279  ASP A CB    1 
ATOM   5459  C  CG    . ASP C 2 279 ? 18.881  59.470  38.499  1.00 69.99  ? 279  ASP A CG    1 
ATOM   5460  O  OD1   . ASP C 2 279 ? 19.626  59.047  37.589  1.00 84.50  ? 279  ASP A OD1   1 
ATOM   5461  O  OD2   . ASP C 2 279 ? 19.267  59.638  39.679  1.00 63.81  ? 279  ASP A OD2   1 
ATOM   5462  N  N     . GLY C 2 280 ? 17.487  61.024  41.458  1.00 46.92  ? 280  GLY A N     1 
ATOM   5463  C  CA    . GLY C 2 280 ? 17.663  60.590  42.836  1.00 45.79  ? 280  GLY A CA    1 
ATOM   5464  C  C     . GLY C 2 280 ? 18.757  59.585  43.159  1.00 47.42  ? 280  GLY A C     1 
ATOM   5465  O  O     . GLY C 2 280 ? 18.883  59.178  44.312  1.00 46.64  ? 280  GLY A O     1 
ATOM   5466  N  N     . ARG C 2 281 ? 19.540  59.175  42.166  1.00 38.06  ? 281  ARG A N     1 
ATOM   5467  C  CA    . ARG C 2 281 ? 20.628  58.226  42.389  1.00 41.68  ? 281  ARG A CA    1 
ATOM   5468  C  C     . ARG C 2 281 ? 21.647  58.829  43.368  1.00 43.67  ? 281  ARG A C     1 
ATOM   5469  O  O     . ARG C 2 281 ? 21.901  60.032  43.336  1.00 33.72  ? 281  ARG A O     1 
ATOM   5470  C  CB    . ARG C 2 281 ? 21.287  57.927  41.051  1.00 42.27  ? 281  ARG A CB    1 
ATOM   5471  C  CG    . ARG C 2 281 ? 22.702  57.480  41.112  1.00 57.45  ? 281  ARG A CG    1 
ATOM   5472  C  CD    . ARG C 2 281 ? 23.235  57.388  39.701  1.00 67.00  ? 281  ARG A CD    1 
ATOM   5473  N  NE    . ARG C 2 281 ? 22.803  58.534  38.916  1.00 65.91  ? 281  ARG A NE    1 
ATOM   5474  C  CZ    . ARG C 2 281 ? 23.276  58.839  37.715  1.00 74.90  ? 281  ARG A CZ    1 
ATOM   5475  N  NH1   . ARG C 2 281 ? 24.210  58.079  37.147  1.00 73.55  ? 281  ARG A NH1   1 
ATOM   5476  N  NH2   . ARG C 2 281 ? 22.810  59.910  37.084  1.00 79.19  ? 281  ARG A NH2   1 
ATOM   5477  N  N     . GLU C 2 282 ? 22.236  57.999  44.230  1.00 39.00  ? 282  GLU A N     1 
ATOM   5478  C  CA    . GLU C 2 282 ? 23.189  58.508  45.209  1.00 37.72  ? 282  GLU A CA    1 
ATOM   5479  C  C     . GLU C 2 282 ? 24.653  58.154  44.971  1.00 39.86  ? 282  GLU A C     1 
ATOM   5480  O  O     . GLU C 2 282 ? 25.550  58.830  45.479  1.00 40.64  ? 282  GLU A O     1 
ATOM   5481  C  CB    . GLU C 2 282 ? 22.776  58.064  46.612  1.00 43.33  ? 282  GLU A CB    1 
ATOM   5482  C  CG    . GLU C 2 282 ? 21.431  58.645  47.047  1.00 62.02  ? 282  GLU A CG    1 
ATOM   5483  C  CD    . GLU C 2 282 ? 21.204  58.520  48.544  1.00 67.24  ? 282  GLU A CD    1 
ATOM   5484  O  OE1   . GLU C 2 282 ? 21.533  57.447  49.094  1.00 70.14  ? 282  GLU A OE1   1 
ATOM   5485  O  OE2   . GLU C 2 282 ? 20.695  59.483  49.162  1.00 55.50  ? 282  GLU A OE2   1 
ATOM   5486  N  N     . ILE C 2 283 ? 24.892  57.083  44.222  1.00 31.70  ? 283  ILE A N     1 
ATOM   5487  C  CA    . ILE C 2 283 ? 26.240  56.664  43.921  1.00 28.53  ? 283  ILE A CA    1 
ATOM   5488  C  C     . ILE C 2 283 ? 26.538  57.074  42.491  1.00 35.31  ? 283  ILE A C     1 
ATOM   5489  O  O     . ILE C 2 283 ? 25.870  56.630  41.557  1.00 34.27  ? 283  ILE A O     1 
ATOM   5490  C  CB    . ILE C 2 283 ? 26.425  55.142  44.006  1.00 25.49  ? 283  ILE A CB    1 
ATOM   5491  C  CG1   . ILE C 2 283 ? 25.945  54.597  45.364  1.00 29.81  ? 283  ILE A CG1   1 
ATOM   5492  C  CG2   . ILE C 2 283 ? 27.874  54.825  43.819  1.00 29.18  ? 283  ILE A CG2   1 
ATOM   5493  C  CD1   . ILE C 2 283 ? 26.588  55.220  46.563  1.00 35.44  ? 283  ILE A CD1   1 
ATOM   5494  N  N     . PHE C 2 284 ? 27.531  57.940  42.325  1.00 29.86  ? 284  PHE A N     1 
ATOM   5495  C  CA    . PHE C 2 284 ? 27.910  58.383  41.007  1.00 25.20  ? 284  PHE A CA    1 
ATOM   5496  C  C     . PHE C 2 284 ? 29.353  58.870  41.014  1.00 31.71  ? 284  PHE A C     1 
ATOM   5497  O  O     . PHE C 2 284 ? 29.918  59.192  42.069  1.00 29.78  ? 284  PHE A O     1 
ATOM   5498  C  CB    . PHE C 2 284 ? 26.952  59.477  40.523  1.00 27.42  ? 284  PHE A CB    1 
ATOM   5499  C  CG    . PHE C 2 284 ? 26.677  60.546  41.546  1.00 29.16  ? 284  PHE A CG    1 
ATOM   5500  C  CD1   . PHE C 2 284 ? 25.482  60.549  42.263  1.00 29.68  ? 284  PHE A CD1   1 
ATOM   5501  C  CD2   . PHE C 2 284 ? 27.584  61.580  41.760  1.00 24.01  ? 284  PHE A CD2   1 
ATOM   5502  C  CE1   . PHE C 2 284 ? 25.186  61.570  43.163  1.00 20.49  ? 284  PHE A CE1   1 
ATOM   5503  C  CE2   . PHE C 2 284 ? 27.293  62.612  42.669  1.00 21.59  ? 284  PHE A CE2   1 
ATOM   5504  C  CZ    . PHE C 2 284 ? 26.086  62.604  43.365  1.00 18.98  ? 284  PHE A CZ    1 
ATOM   5505  N  N     . THR C 2 285 ? 29.948  58.911  39.829  1.00 23.78  ? 285  THR A N     1 
ATOM   5506  C  CA    . THR C 2 285 ? 31.334  59.331  39.669  1.00 21.37  ? 285  THR A CA    1 
ATOM   5507  C  C     . THR C 2 285 ? 31.548  60.869  39.707  1.00 27.51  ? 285  THR A C     1 
ATOM   5508  O  O     . THR C 2 285 ? 30.602  61.669  39.649  1.00 24.72  ? 285  THR A O     1 
ATOM   5509  C  CB    . THR C 2 285 ? 31.882  58.779  38.323  1.00 33.04  ? 285  THR A CB    1 
ATOM   5510  O  OG1   . THR C 2 285 ? 31.331  59.549  37.242  1.00 28.55  ? 285  THR A OG1   1 
ATOM   5511  C  CG2   . THR C 2 285 ? 31.437  57.278  38.115  1.00 21.74  ? 285  THR A CG2   1 
ATOM   5512  N  N     . LEU C 2 286 ? 32.807  61.266  39.823  1.00 22.61  ? 286  LEU A N     1 
ATOM   5513  C  CA    . LEU C 2 286 ? 33.179  62.659  39.833  1.00 24.07  ? 286  LEU A CA    1 
ATOM   5514  C  C     . LEU C 2 286 ? 32.756  63.226  38.481  1.00 29.56  ? 286  LEU A C     1 
ATOM   5515  O  O     . LEU C 2 286 ? 32.162  64.310  38.387  1.00 33.06  ? 286  LEU A O     1 
ATOM   5516  C  CB    . LEU C 2 286 ? 34.695  62.781  39.957  1.00 21.69  ? 286  LEU A CB    1 
ATOM   5517  C  CG    . LEU C 2 286 ? 35.259  64.010  40.644  1.00 28.35  ? 286  LEU A CG    1 
ATOM   5518  C  CD1   . LEU C 2 286 ? 36.710  64.118  40.341  1.00 27.71  ? 286  LEU A CD1   1 
ATOM   5519  C  CD2   . LEU C 2 286 ? 34.556  65.217  40.215  1.00 22.94  ? 286  LEU A CD2   1 
ATOM   5520  N  N     . GLU C 2 287 ? 33.055  62.477  37.430  1.00 24.17  ? 287  GLU A N     1 
ATOM   5521  C  CA    . GLU C 2 287 ? 32.729  62.919  36.088  1.00 32.65  ? 287  GLU A CA    1 
ATOM   5522  C  C     . GLU C 2 287 ? 31.231  63.111  35.859  1.00 33.59  ? 287  GLU A C     1 
ATOM   5523  O  O     . GLU C 2 287 ? 30.821  64.105  35.249  1.00 35.12  ? 287  GLU A O     1 
ATOM   5524  C  CB    . GLU C 2 287 ? 33.320  61.943  35.075  1.00 33.93  ? 287  GLU A CB    1 
ATOM   5525  C  CG    . GLU C 2 287 ? 33.453  62.492  33.667  1.00 53.28  ? 287  GLU A CG    1 
ATOM   5526  C  CD    . GLU C 2 287 ? 34.309  63.764  33.579  1.00 57.04  ? 287  GLU A CD    1 
ATOM   5527  O  OE1   . GLU C 2 287 ? 35.306  63.885  34.335  1.00 45.23  ? 287  GLU A OE1   1 
ATOM   5528  O  OE2   . GLU C 2 287 ? 33.984  64.630  32.730  1.00 56.41  ? 287  GLU A OE2   1 
ATOM   5529  N  N     . GLU C 2 288 ? 30.408  62.190  36.359  1.00 30.47  ? 288  GLU A N     1 
ATOM   5530  C  CA    . GLU C 2 288 ? 28.959  62.313  36.193  1.00 32.84  ? 288  GLU A CA    1 
ATOM   5531  C  C     . GLU C 2 288 ? 28.404  63.555  36.926  1.00 37.15  ? 288  GLU A C     1 
ATOM   5532  O  O     . GLU C 2 288 ? 27.535  64.267  36.425  1.00 45.01  ? 288  GLU A O     1 
ATOM   5533  C  CB    . GLU C 2 288 ? 28.273  61.049  36.704  1.00 32.05  ? 288  GLU A CB    1 
ATOM   5534  C  CG    . GLU C 2 288 ? 28.560  59.793  35.857  1.00 47.65  ? 288  GLU A CG    1 
ATOM   5535  C  CD    . GLU C 2 288 ? 27.844  58.560  36.384  1.00 45.07  ? 288  GLU A CD    1 
ATOM   5536  O  OE1   . GLU C 2 288 ? 28.293  58.018  37.411  1.00 52.09  ? 288  GLU A OE1   1 
ATOM   5537  O  OE2   . GLU C 2 288 ? 26.823  58.143  35.790  1.00 55.07  ? 288  GLU A OE2   1 
ATOM   5538  N  N     . PHE C 2 289 ? 28.926  63.805  38.114  1.00 32.15  ? 289  PHE A N     1 
ATOM   5539  C  CA    . PHE C 2 289 ? 28.519  64.923  38.920  1.00 30.96  ? 289  PHE A CA    1 
ATOM   5540  C  C     . PHE C 2 289 ? 28.751  66.218  38.156  1.00 30.16  ? 289  PHE A C     1 
ATOM   5541  O  O     . PHE C 2 289 ? 27.879  67.068  38.105  1.00 30.72  ? 289  PHE A O     1 
ATOM   5542  C  CB    . PHE C 2 289 ? 29.310  64.899  40.233  1.00 30.91  ? 289  PHE A CB    1 
ATOM   5543  C  CG    . PHE C 2 289 ? 29.203  66.143  41.021  1.00 19.41  ? 289  PHE A CG    1 
ATOM   5544  C  CD1   . PHE C 2 289 ? 27.957  66.554  41.540  1.00 24.78  ? 289  PHE A CD1   1 
ATOM   5545  C  CD2   . PHE C 2 289 ? 30.333  66.917  41.252  1.00 17.26  ? 289  PHE A CD2   1 
ATOM   5546  C  CE1   . PHE C 2 289 ? 27.838  67.724  42.285  1.00 22.13  ? 289  PHE A CE1   1 
ATOM   5547  C  CE2   . PHE C 2 289 ? 30.238  68.117  42.006  1.00 25.54  ? 289  PHE A CE2   1 
ATOM   5548  C  CZ    . PHE C 2 289 ? 28.990  68.520  42.524  1.00 28.95  ? 289  PHE A CZ    1 
ATOM   5549  N  N     . ILE C 2 290 ? 29.921  66.355  37.545  1.00 34.59  ? 290  ILE A N     1 
ATOM   5550  C  CA    . ILE C 2 290 ? 30.255  67.549  36.764  1.00 34.88  ? 290  ILE A CA    1 
ATOM   5551  C  C     . ILE C 2 290 ? 29.203  67.780  35.687  1.00 36.64  ? 290  ILE A C     1 
ATOM   5552  O  O     . ILE C 2 290 ? 28.631  68.864  35.563  1.00 38.24  ? 290  ILE A O     1 
ATOM   5553  C  CB    . ILE C 2 290 ? 31.618  67.381  36.056  1.00 40.02  ? 290  ILE A CB    1 
ATOM   5554  C  CG1   . ILE C 2 290 ? 32.761  67.529  37.066  1.00 41.69  ? 290  ILE A CG1   1 
ATOM   5555  C  CG2   . ILE C 2 290 ? 31.729  68.348  34.897  1.00 32.81  ? 290  ILE A CG2   1 
ATOM   5556  C  CD1   . ILE C 2 290 ? 34.113  67.034  36.530  1.00 41.95  ? 290  ILE A CD1   1 
ATOM   5557  N  N     . GLN C 2 291 ? 28.948  66.738  34.918  1.00 34.84  ? 291  GLN A N     1 
ATOM   5558  C  CA    . GLN C 2 291 ? 27.991  66.804  33.828  1.00 40.81  ? 291  GLN A CA    1 
ATOM   5559  C  C     . GLN C 2 291 ? 26.551  67.081  34.246  1.00 36.41  ? 291  GLN A C     1 
ATOM   5560  O  O     . GLN C 2 291 ? 25.781  67.644  33.484  1.00 38.86  ? 291  GLN A O     1 
ATOM   5561  C  CB    . GLN C 2 291 ? 28.075  65.507  33.013  1.00 44.01  ? 291  GLN A CB    1 
ATOM   5562  C  CG    . GLN C 2 291 ? 29.207  65.528  31.998  1.00 57.43  ? 291  GLN A CG    1 
ATOM   5563  C  CD    . GLN C 2 291 ? 29.782  64.151  31.723  1.00 72.85  ? 291  GLN A CD    1 
ATOM   5564  O  OE1   . GLN C 2 291 ? 29.055  63.145  31.714  1.00 71.40  ? 291  GLN A OE1   1 
ATOM   5565  N  NE2   . GLN C 2 291 ? 31.099  64.095  31.488  1.00 66.87  ? 291  GLN A NE2   1 
ATOM   5566  N  N     . ALA C 2 292 ? 26.171  66.711  35.457  1.00 34.05  ? 292  ALA A N     1 
ATOM   5567  C  CA    . ALA C 2 292 ? 24.796  66.965  35.862  1.00 28.67  ? 292  ALA A CA    1 
ATOM   5568  C  C     . ALA C 2 292 ? 24.640  68.191  36.732  1.00 34.53  ? 292  ALA A C     1 
ATOM   5569  O  O     . ALA C 2 292 ? 23.510  68.616  36.997  1.00 33.84  ? 292  ALA A O     1 
ATOM   5570  C  CB    . ALA C 2 292 ? 24.237  65.768  36.585  1.00 24.10  ? 292  ALA A CB    1 
ATOM   5571  N  N     . PHE C 2 293 ? 25.753  68.788  37.158  1.00 32.48  ? 293  PHE A N     1 
ATOM   5572  C  CA    . PHE C 2 293 ? 25.642  69.948  38.047  1.00 33.18  ? 293  PHE A CA    1 
ATOM   5573  C  C     . PHE C 2 293 ? 24.821  71.137  37.527  1.00 26.20  ? 293  PHE A C     1 
ATOM   5574  O  O     . PHE C 2 293 ? 24.921  71.510  36.374  1.00 31.71  ? 293  PHE A O     1 
ATOM   5575  C  CB    . PHE C 2 293 ? 27.021  70.456  38.463  1.00 37.96  ? 293  PHE A CB    1 
ATOM   5576  C  CG    . PHE C 2 293 ? 26.958  71.545  39.484  1.00 33.14  ? 293  PHE A CG    1 
ATOM   5577  C  CD1   . PHE C 2 293 ? 26.573  71.267  40.779  1.00 41.02  ? 293  PHE A CD1   1 
ATOM   5578  C  CD2   . PHE C 2 293 ? 27.198  72.868  39.127  1.00 40.52  ? 293  PHE A CD2   1 
ATOM   5579  C  CE1   . PHE C 2 293 ? 26.420  72.301  41.710  1.00 42.74  ? 293  PHE A CE1   1 
ATOM   5580  C  CE2   . PHE C 2 293 ? 27.050  73.903  40.040  1.00 31.53  ? 293  PHE A CE2   1 
ATOM   5581  C  CZ    . PHE C 2 293 ? 26.662  73.624  41.327  1.00 39.19  ? 293  PHE A CZ    1 
ATOM   5582  N  N     . THR C 2 294 ? 24.037  71.741  38.411  1.00 26.19  ? 294  THR A N     1 
ATOM   5583  C  CA    . THR C 2 294 ? 23.198  72.880  38.067  1.00 28.70  ? 294  THR A CA    1 
ATOM   5584  C  C     . THR C 2 294 ? 22.907  73.523  39.382  1.00 25.37  ? 294  THR A C     1 
ATOM   5585  O  O     . THR C 2 294 ? 22.633  72.801  40.326  1.00 27.43  ? 294  THR A O     1 
ATOM   5586  C  CB    . THR C 2 294 ? 21.791  72.471  37.535  1.00 30.21  ? 294  THR A CB    1 
ATOM   5587  O  OG1   . THR C 2 294 ? 21.899  71.807  36.276  1.00 49.09  ? 294  THR A OG1   1 
ATOM   5588  C  CG2   . THR C 2 294 ? 20.944  73.683  37.368  1.00 29.35  ? 294  THR A CG2   1 
ATOM   5589  N  N     . TRP C 2 295 ? 22.942  74.854  39.444  1.00 16.63  ? 295  TRP A N     1 
ATOM   5590  C  CA    . TRP C 2 295 ? 22.630  75.559  40.673  1.00 21.06  ? 295  TRP A CA    1 
ATOM   5591  C  C     . TRP C 2 295 ? 21.151  75.382  41.025  1.00 31.73  ? 295  TRP A C     1 
ATOM   5592  O  O     . TRP C 2 295 ? 20.757  75.574  42.183  1.00 31.83  ? 295  TRP A O     1 
ATOM   5593  C  CB    . TRP C 2 295 ? 22.942  77.049  40.522  1.00 20.95  ? 295  TRP A CB    1 
ATOM   5594  C  CG    . TRP C 2 295 ? 24.418  77.295  40.362  1.00 35.65  ? 295  TRP A CG    1 
ATOM   5595  C  CD1   . TRP C 2 295 ? 25.073  77.717  39.233  1.00 22.05  ? 295  TRP A CD1   1 
ATOM   5596  C  CD2   . TRP C 2 295 ? 25.428  77.062  41.353  1.00 19.45  ? 295  TRP A CD2   1 
ATOM   5597  N  NE1   . TRP C 2 295 ? 26.428  77.754  39.464  1.00 32.28  ? 295  TRP A NE1   1 
ATOM   5598  C  CE2   . TRP C 2 295 ? 26.673  77.358  40.758  1.00 34.06  ? 295  TRP A CE2   1 
ATOM   5599  C  CE3   . TRP C 2 295 ? 25.400  76.626  42.682  1.00 28.20  ? 295  TRP A CE3   1 
ATOM   5600  C  CZ2   . TRP C 2 295 ? 27.893  77.228  41.460  1.00 32.74  ? 295  TRP A CZ2   1 
ATOM   5601  C  CZ3   . TRP C 2 295 ? 26.615  76.492  43.380  1.00 26.28  ? 295  TRP A CZ3   1 
ATOM   5602  C  CH2   . TRP C 2 295 ? 27.837  76.792  42.766  1.00 17.87  ? 295  TRP A CH2   1 
ATOM   5603  N  N     . GLU C 2 296 ? 20.340  75.013  40.028  1.00 32.99  ? 296  GLU A N     1 
ATOM   5604  C  CA    . GLU C 2 296 ? 18.902  74.818  40.231  1.00 40.55  ? 296  GLU A CA    1 
ATOM   5605  C  C     . GLU C 2 296 ? 18.678  73.645  41.156  1.00 43.01  ? 296  GLU A C     1 
ATOM   5606  O  O     . GLU C 2 296 ? 17.601  73.534  41.756  1.00 44.85  ? 296  GLU A O     1 
ATOM   5607  C  CB    . GLU C 2 296 ? 18.170  74.544  38.914  1.00 39.64  ? 296  GLU A CB    1 
ATOM   5608  C  CG    . GLU C 2 296 ? 18.349  75.626  37.856  1.00 58.95  ? 296  GLU A CG    1 
ATOM   5609  C  CD    . GLU C 2 296 ? 17.846  75.183  36.476  1.00 81.54  ? 296  GLU A CD    1 
ATOM   5610  O  OE1   . GLU C 2 296 ? 16.759  75.658  36.042  1.00 81.30  ? 296  GLU A OE1   1 
ATOM   5611  O  OE2   . GLU C 2 296 ? 18.539  74.349  35.826  1.00 82.43  ? 296  GLU A OE2   1 
ATOM   5612  N  N     . ARG C 2 297 ? 19.690  72.778  41.273  1.00 36.60  ? 297  ARG A N     1 
ATOM   5613  C  CA    . ARG C 2 297 ? 19.589  71.614  42.142  1.00 33.99  ? 297  ARG A CA    1 
ATOM   5614  C  C     . ARG C 2 297 ? 20.414  71.685  43.419  1.00 31.64  ? 297  ARG A C     1 
ATOM   5615  O  O     . ARG C 2 297 ? 20.712  70.652  44.026  1.00 34.76  ? 297  ARG A O     1 
ATOM   5616  C  CB    . ARG C 2 297 ? 19.931  70.328  41.371  1.00 33.70  ? 297  ARG A CB    1 
ATOM   5617  C  CG    . ARG C 2 297 ? 18.882  69.967  40.323  1.00 34.63  ? 297  ARG A CG    1 
ATOM   5618  C  CD    . ARG C 2 297 ? 19.018  68.511  39.888  1.00 39.94  ? 297  ARG A CD    1 
ATOM   5619  N  NE    . ARG C 2 297 ? 18.494  67.578  40.891  1.00 34.79  ? 297  ARG A NE    1 
ATOM   5620  C  CZ    . ARG C 2 297 ? 17.194  67.391  41.153  1.00 46.86  ? 297  ARG A CZ    1 
ATOM   5621  N  NH1   . ARG C 2 297 ? 16.255  68.063  40.486  1.00 31.50  ? 297  ARG A NH1   1 
ATOM   5622  N  NH2   . ARG C 2 297 ? 16.827  66.534  42.102  1.00 45.90  ? 297  ARG A NH2   1 
ATOM   5623  N  N     . VAL C 2 298 ? 20.781  72.892  43.834  1.00 27.02  ? 298  VAL A N     1 
ATOM   5624  C  CA    . VAL C 2 298 ? 21.547  73.058  45.074  1.00 27.11  ? 298  VAL A CA    1 
ATOM   5625  C  C     . VAL C 2 298 ? 20.598  73.516  46.163  1.00 33.53  ? 298  VAL A C     1 
ATOM   5626  O  O     . VAL C 2 298 ? 19.937  74.517  45.997  1.00 33.10  ? 298  VAL A O     1 
ATOM   5627  C  CB    . VAL C 2 298 ? 22.652  74.126  44.934  1.00 34.68  ? 298  VAL A CB    1 
ATOM   5628  C  CG1   . VAL C 2 298 ? 23.205  74.471  46.310  1.00 26.07  ? 298  VAL A CG1   1 
ATOM   5629  C  CG2   . VAL C 2 298 ? 23.776  73.613  43.991  1.00 27.32  ? 298  VAL A CG2   1 
ATOM   5630  N  N     . SER C 2 299 ? 20.522  72.792  47.276  1.00 36.44  ? 299  SER A N     1 
ATOM   5631  C  CA    . SER C 2 299 ? 19.607  73.195  48.343  1.00 31.85  ? 299  SER A CA    1 
ATOM   5632  C  C     . SER C 2 299 ? 20.351  74.043  49.373  1.00 26.54  ? 299  SER A C     1 
ATOM   5633  O  O     . SER C 2 299 ? 21.519  73.816  49.643  1.00 29.19  ? 299  SER A O     1 
ATOM   5634  C  CB    . SER C 2 299 ? 18.976  71.953  48.986  1.00 32.93  ? 299  SER A CB    1 
ATOM   5635  O  OG    . SER C 2 299 ? 19.948  71.176  49.659  1.00 48.65  ? 299  SER A OG    1 
ATOM   5636  N  N     . LEU C 2 300 ? 19.676  75.017  49.967  1.00 26.57  ? 300  LEU A N     1 
ATOM   5637  C  CA    . LEU C 2 300 ? 20.355  75.915  50.891  1.00 28.43  ? 300  LEU A CA    1 
ATOM   5638  C  C     . LEU C 2 300 ? 20.396  75.654  52.407  1.00 32.19  ? 300  LEU A C     1 
ATOM   5639  O  O     . LEU C 2 300 ? 20.935  76.459  53.168  1.00 35.11  ? 300  LEU A O     1 
ATOM   5640  C  CB    . LEU C 2 300 ? 19.852  77.325  50.616  1.00 28.14  ? 300  LEU A CB    1 
ATOM   5641  C  CG    . LEU C 2 300 ? 20.077  77.765  49.161  1.00 38.02  ? 300  LEU A CG    1 
ATOM   5642  C  CD1   . LEU C 2 300 ? 19.421  79.142  48.899  1.00 27.88  ? 300  LEU A CD1   1 
ATOM   5643  C  CD2   . LEU C 2 300 ? 21.586  77.798  48.886  1.00 19.73  ? 300  LEU A CD2   1 
ATOM   5644  N  N     . GLY C 2 301 ? 19.850  74.536  52.853  1.00 29.50  ? 301  GLY A N     1 
ATOM   5645  C  CA    . GLY C 2 301 ? 19.897  74.244  54.269  1.00 36.89  ? 301  GLY A CA    1 
ATOM   5646  C  C     . GLY C 2 301 ? 21.272  73.742  54.674  1.00 41.33  ? 301  GLY A C     1 
ATOM   5647  O  O     . GLY C 2 301 ? 21.957  73.095  53.867  1.00 49.84  ? 301  GLY A O     1 
ATOM   5648  N  N     . GLY C 2 302 ? 21.679  74.038  55.909  1.00 37.98  ? 302  GLY A N     1 
ATOM   5649  C  CA    . GLY C 2 302 ? 22.975  73.593  56.399  1.00 38.60  ? 302  GLY A CA    1 
ATOM   5650  C  C     . GLY C 2 302 ? 22.969  72.102  56.691  1.00 39.37  ? 302  GLY A C     1 
ATOM   5651  O  O     . GLY C 2 302 ? 22.379  71.685  57.682  1.00 44.36  ? 302  GLY A O     1 
ATOM   5652  N  N     . PRO C 2 303 ? 23.653  71.271  55.876  1.00 41.65  ? 303  PRO A N     1 
ATOM   5653  C  CA    . PRO C 2 303 ? 23.689  69.816  56.070  1.00 34.15  ? 303  PRO A CA    1 
ATOM   5654  C  C     . PRO C 2 303 ? 24.528  69.267  57.225  1.00 37.88  ? 303  PRO A C     1 
ATOM   5655  O  O     . PRO C 2 303 ? 25.697  69.610  57.398  1.00 24.07  ? 303  PRO A O     1 
ATOM   5656  C  CB    . PRO C 2 303 ? 24.189  69.312  54.720  1.00 27.99  ? 303  PRO A CB    1 
ATOM   5657  C  CG    . PRO C 2 303 ? 25.183  70.360  54.371  1.00 30.83  ? 303  PRO A CG    1 
ATOM   5658  C  CD    . PRO C 2 303 ? 24.488  71.658  54.723  1.00 30.05  ? 303  PRO A CD    1 
ATOM   5659  N  N     . VAL C 2 304 ? 23.918  68.391  58.010  1.00 35.81  ? 304  VAL A N     1 
ATOM   5660  C  CA    . VAL C 2 304 ? 24.634  67.770  59.100  1.00 37.91  ? 304  VAL A CA    1 
ATOM   5661  C  C     . VAL C 2 304 ? 25.509  66.722  58.440  1.00 37.90  ? 304  VAL A C     1 
ATOM   5662  O  O     . VAL C 2 304 ? 25.048  65.967  57.598  1.00 40.09  ? 304  VAL A O     1 
ATOM   5663  C  CB    . VAL C 2 304 ? 23.660  67.083  60.080  1.00 42.94  ? 304  VAL A CB    1 
ATOM   5664  C  CG1   . VAL C 2 304 ? 24.432  66.224  61.112  1.00 26.13  ? 304  VAL A CG1   1 
ATOM   5665  C  CG2   . VAL C 2 304 ? 22.822  68.144  60.766  1.00 28.60  ? 304  VAL A CG2   1 
ATOM   5666  N  N     . PHE C 2 305 ? 26.780  66.697  58.796  1.00 38.53  ? 305  PHE A N     1 
ATOM   5667  C  CA    . PHE C 2 305 ? 27.676  65.714  58.234  1.00 36.28  ? 305  PHE A CA    1 
ATOM   5668  C  C     . PHE C 2 305 ? 27.467  64.477  59.093  1.00 41.43  ? 305  PHE A C     1 
ATOM   5669  O  O     . PHE C 2 305 ? 27.792  64.494  60.288  1.00 42.66  ? 305  PHE A O     1 
ATOM   5670  C  CB    . PHE C 2 305 ? 29.100  66.217  58.337  1.00 37.63  ? 305  PHE A CB    1 
ATOM   5671  C  CG    . PHE C 2 305 ? 30.097  65.331  57.703  1.00 37.12  ? 305  PHE A CG    1 
ATOM   5672  C  CD1   . PHE C 2 305 ? 30.547  64.184  58.362  1.00 44.69  ? 305  PHE A CD1   1 
ATOM   5673  C  CD2   . PHE C 2 305 ? 30.622  65.644  56.457  1.00 32.55  ? 305  PHE A CD2   1 
ATOM   5674  C  CE1   . PHE C 2 305 ? 31.526  63.348  57.776  1.00 41.00  ? 305  PHE A CE1   1 
ATOM   5675  C  CE2   . PHE C 2 305 ? 31.587  64.830  55.869  1.00 35.79  ? 305  PHE A CE2   1 
ATOM   5676  C  CZ    . PHE C 2 305 ? 32.042  63.678  56.529  1.00 35.43  ? 305  PHE A CZ    1 
ATOM   5677  N  N     . ASP C 2 306 ? 26.909  63.430  58.470  1.00 34.48  ? 306  ASP A N     1 
ATOM   5678  C  CA    . ASP C 2 306 ? 26.576  62.130  59.081  1.00 26.41  ? 306  ASP A CA    1 
ATOM   5679  C  C     . ASP C 2 306 ? 27.652  61.023  58.825  1.00 29.93  ? 306  ASP A C     1 
ATOM   5680  O  O     . ASP C 2 306 ? 27.703  60.408  57.767  1.00 28.05  ? 306  ASP A O     1 
ATOM   5681  C  CB    . ASP C 2 306 ? 25.210  61.711  58.511  1.00 30.08  ? 306  ASP A CB    1 
ATOM   5682  C  CG    . ASP C 2 306 ? 24.634  60.441  59.146  1.00 30.66  ? 306  ASP A CG    1 
ATOM   5683  O  OD1   . ASP C 2 306 ? 23.558  59.996  58.678  1.00 32.24  ? 306  ASP A OD1   1 
ATOM   5684  O  OD2   . ASP C 2 306 ? 25.220  59.895  60.097  1.00 33.98  ? 306  ASP A OD2   1 
ATOM   5685  N  N     . LEU C 2 307 ? 28.481  60.751  59.817  1.00 26.22  ? 307  LEU A N     1 
ATOM   5686  C  CA    . LEU C 2 307 ? 29.532  59.762  59.681  1.00 27.50  ? 307  LEU A CA    1 
ATOM   5687  C  C     . LEU C 2 307 ? 28.988  58.396  59.308  1.00 31.31  ? 307  LEU A C     1 
ATOM   5688  O  O     . LEU C 2 307 ? 29.578  57.647  58.516  1.00 36.42  ? 307  LEU A O     1 
ATOM   5689  C  CB    . LEU C 2 307 ? 30.309  59.687  60.993  1.00 34.12  ? 307  LEU A CB    1 
ATOM   5690  C  CG    . LEU C 2 307 ? 31.695  59.065  60.967  1.00 42.83  ? 307  LEU A CG    1 
ATOM   5691  C  CD1   . LEU C 2 307 ? 32.581  59.811  59.983  1.00 50.16  ? 307  LEU A CD1   1 
ATOM   5692  C  CD2   . LEU C 2 307 ? 32.280  59.121  62.354  1.00 48.93  ? 307  LEU A CD2   1 
ATOM   5693  N  N     . GLU C 2 308 ? 27.850  58.057  59.873  1.00 28.24  ? 308  GLU A N     1 
ATOM   5694  C  CA    . GLU C 2 308 ? 27.256  56.770  59.576  1.00 36.04  ? 308  GLU A CA    1 
ATOM   5695  C  C     . GLU C 2 308 ? 26.927  56.609  58.102  1.00 38.36  ? 308  GLU A C     1 
ATOM   5696  O  O     . GLU C 2 308 ? 27.198  55.553  57.523  1.00 34.46  ? 308  GLU A O     1 
ATOM   5697  C  CB    . GLU C 2 308 ? 26.005  56.547  60.425  1.00 33.64  ? 308  GLU A CB    1 
ATOM   5698  C  CG    . GLU C 2 308 ? 26.363  56.037  61.801  1.00 54.87  ? 308  GLU A CG    1 
ATOM   5699  C  CD    . GLU C 2 308 ? 27.195  54.765  61.722  1.00 70.10  ? 308  GLU A CD    1 
ATOM   5700  O  OE1   . GLU C 2 308 ? 28.351  54.763  62.215  1.00 69.62  ? 308  GLU A OE1   1 
ATOM   5701  O  OE2   . GLU C 2 308 ? 26.687  53.767  61.149  1.00 74.65  ? 308  GLU A OE2   1 
ATOM   5702  N  N     . LYS C 2 309 ? 26.356  57.647  57.484  1.00 31.08  ? 309  LYS A N     1 
ATOM   5703  C  CA    . LYS C 2 309 ? 26.027  57.517  56.094  1.00 24.04  ? 309  LYS A CA    1 
ATOM   5704  C  C     . LYS C 2 309 ? 27.282  57.477  55.237  1.00 26.26  ? 309  LYS A C     1 
ATOM   5705  O  O     . LYS C 2 309 ? 27.303  56.815  54.200  1.00 29.20  ? 309  LYS A O     1 
ATOM   5706  C  CB    . LYS C 2 309 ? 25.105  58.619  55.605  1.00 28.02  ? 309  LYS A CB    1 
ATOM   5707  C  CG    . LYS C 2 309 ? 24.647  58.319  54.184  1.00 25.60  ? 309  LYS A CG    1 
ATOM   5708  C  CD    . LYS C 2 309 ? 23.414  59.044  53.798  1.00 32.84  ? 309  LYS A CD    1 
ATOM   5709  C  CE    . LYS C 2 309 ? 22.860  58.570  52.430  1.00 42.80  ? 309  LYS A CE    1 
ATOM   5710  N  NZ    . LYS C 2 309 ? 21.798  59.518  51.891  1.00 43.10  ? 309  LYS A NZ    1 
ATOM   5711  N  N     . LEU C 2 310 ? 28.334  58.142  55.694  1.00 22.92  ? 310  LEU A N     1 
ATOM   5712  C  CA    . LEU C 2 310 ? 29.602  58.147  54.971  1.00 24.67  ? 310  LEU A CA    1 
ATOM   5713  C  C     . LEU C 2 310 ? 30.130  56.697  55.006  1.00 35.65  ? 310  LEU A C     1 
ATOM   5714  O  O     . LEU C 2 310 ? 30.551  56.151  53.971  1.00 34.49  ? 310  LEU A O     1 
ATOM   5715  C  CB    . LEU C 2 310 ? 30.596  59.110  55.649  1.00 23.62  ? 310  LEU A CB    1 
ATOM   5716  C  CG    . LEU C 2 310 ? 31.788  59.759  54.907  1.00 34.10  ? 310  LEU A CG    1 
ATOM   5717  C  CD1   . LEU C 2 310 ? 33.086  59.643  55.750  1.00 23.30  ? 310  LEU A CD1   1 
ATOM   5718  C  CD2   . LEU C 2 310 ? 31.984  59.127  53.558  1.00 20.18  ? 310  LEU A CD2   1 
ATOM   5719  N  N     . ARG C 2 311 ? 30.096  56.064  56.187  1.00 34.32  ? 311  ARG A N     1 
ATOM   5720  C  CA    . ARG C 2 311 ? 30.569  54.683  56.284  1.00 30.76  ? 311  ARG A CA    1 
ATOM   5721  C  C     . ARG C 2 311 ? 29.753  53.801  55.364  1.00 33.46  ? 311  ARG A C     1 
ATOM   5722  O  O     . ARG C 2 311 ? 30.307  52.985  54.639  1.00 30.03  ? 311  ARG A O     1 
ATOM   5723  C  CB    . ARG C 2 311 ? 30.470  54.134  57.706  1.00 30.85  ? 311  ARG A CB    1 
ATOM   5724  C  CG    . ARG C 2 311 ? 31.497  54.710  58.633  1.00 34.79  ? 311  ARG A CG    1 
ATOM   5725  C  CD    . ARG C 2 311 ? 31.160  54.431  60.085  1.00 50.47  ? 311  ARG A CD    1 
ATOM   5726  N  NE    . ARG C 2 311 ? 32.266  53.752  60.728  1.00 57.83  ? 311  ARG A NE    1 
ATOM   5727  C  CZ    . ARG C 2 311 ? 32.502  52.456  60.594  1.00 57.70  ? 311  ARG A CZ    1 
ATOM   5728  N  NH1   . ARG C 2 311 ? 31.695  51.707  59.849  1.00 59.77  ? 311  ARG A NH1   1 
ATOM   5729  N  NH2   . ARG C 2 311 ? 33.559  51.917  61.182  1.00 65.78  ? 311  ARG A NH2   1 
ATOM   5730  N  N     . TRP C 2 312 ? 28.432  53.954  55.390  1.00 32.01  ? 312  TRP A N     1 
ATOM   5731  C  CA    . TRP C 2 312 ? 27.593  53.130  54.515  1.00 31.57  ? 312  TRP A CA    1 
ATOM   5732  C  C     . TRP C 2 312 ? 28.089  53.247  53.083  1.00 32.12  ? 312  TRP A C     1 
ATOM   5733  O  O     . TRP C 2 312 ? 28.260  52.256  52.368  1.00 29.91  ? 312  TRP A O     1 
ATOM   5734  C  CB    . TRP C 2 312 ? 26.133  53.595  54.521  1.00 23.64  ? 312  TRP A CB    1 
ATOM   5735  C  CG    . TRP C 2 312 ? 25.353  52.990  53.418  1.00 21.53  ? 312  TRP A CG    1 
ATOM   5736  C  CD1   . TRP C 2 312 ? 24.927  51.689  53.336  1.00 27.97  ? 312  TRP A CD1   1 
ATOM   5737  C  CD2   . TRP C 2 312 ? 24.923  53.629  52.210  1.00 19.93  ? 312  TRP A CD2   1 
ATOM   5738  N  NE1   . TRP C 2 312 ? 24.258  51.485  52.159  1.00 19.06  ? 312  TRP A NE1   1 
ATOM   5739  C  CE2   . TRP C 2 312 ? 24.238  52.653  51.444  1.00 22.95  ? 312  TRP A CE2   1 
ATOM   5740  C  CE3   . TRP C 2 312 ? 25.047  54.928  51.699  1.00 21.68  ? 312  TRP A CE3   1 
ATOM   5741  C  CZ2   . TRP C 2 312 ? 23.673  52.937  50.183  1.00 31.69  ? 312  TRP A CZ2   1 
ATOM   5742  C  CZ3   . TRP C 2 312 ? 24.480  55.221  50.429  1.00 23.96  ? 312  TRP A CZ3   1 
ATOM   5743  C  CH2   . TRP C 2 312 ? 23.804  54.226  49.693  1.00 32.48  ? 312  TRP A CH2   1 
ATOM   5744  N  N     . MET C 2 313 ? 28.283  54.486  52.668  1.00 27.70  ? 313  MET A N     1 
ATOM   5745  C  CA    . MET C 2 313 ? 28.721  54.749  51.324  1.00 30.69  ? 313  MET A CA    1 
ATOM   5746  C  C     . MET C 2 313 ? 30.108  54.133  51.056  1.00 29.81  ? 313  MET A C     1 
ATOM   5747  O  O     . MET C 2 313 ? 30.333  53.535  50.008  1.00 27.87  ? 313  MET A O     1 
ATOM   5748  C  CB    . MET C 2 313 ? 28.732  56.256  51.089  1.00 31.23  ? 313  MET A CB    1 
ATOM   5749  C  CG    . MET C 2 313 ? 29.164  56.656  49.682  1.00 41.45  ? 313  MET A CG    1 
ATOM   5750  S  SD    . MET C 2 313 ? 28.609  58.315  49.259  1.00 51.97  ? 313  MET A SD    1 
ATOM   5751  C  CE    . MET C 2 313 ? 26.889  58.045  48.983  1.00 42.99  ? 313  MET A CE    1 
ATOM   5752  N  N     . ASN C 2 314 ? 31.020  54.256  52.011  1.00 22.77  ? 314  ASN A N     1 
ATOM   5753  C  CA    . ASN C 2 314 ? 32.356  53.731  51.815  1.00 26.47  ? 314  ASN A CA    1 
ATOM   5754  C  C     . ASN C 2 314 ? 32.257  52.231  51.583  1.00 33.11  ? 314  ASN A C     1 
ATOM   5755  O  O     . ASN C 2 314 ? 32.947  51.691  50.721  1.00 32.49  ? 314  ASN A O     1 
ATOM   5756  C  CB    . ASN C 2 314 ? 33.223  54.014  53.029  1.00 22.26  ? 314  ASN A CB    1 
ATOM   5757  C  CG    . ASN C 2 314 ? 34.694  54.092  52.692  1.00 26.88  ? 314  ASN A CG    1 
ATOM   5758  O  OD1   . ASN C 2 314 ? 35.118  54.908  51.871  1.00 23.62  ? 314  ASN A OD1   1 
ATOM   5759  N  ND2   . ASN C 2 314 ? 35.488  53.265  53.351  1.00 25.53  ? 314  ASN A ND2   1 
ATOM   5760  N  N     . GLY C 2 315 ? 31.406  51.563  52.362  1.00 28.27  ? 315  GLY A N     1 
ATOM   5761  C  CA    . GLY C 2 315 ? 31.219  50.135  52.209  1.00 30.72  ? 315  GLY A CA    1 
ATOM   5762  C  C     . GLY C 2 315 ? 30.618  49.868  50.828  1.00 38.02  ? 315  GLY A C     1 
ATOM   5763  O  O     . GLY C 2 315 ? 30.988  48.904  50.153  1.00 36.49  ? 315  GLY A O     1 
ATOM   5764  N  N     . LYS C 2 316 ? 29.708  50.739  50.391  1.00 26.05  ? 316  LYS A N     1 
ATOM   5765  C  CA    . LYS C 2 316 ? 29.083  50.595  49.088  1.00 23.24  ? 316  LYS A CA    1 
ATOM   5766  C  C     . LYS C 2 316 ? 30.134  50.689  47.945  1.00 31.45  ? 316  LYS A C     1 
ATOM   5767  O  O     . LYS C 2 316 ? 30.041  49.979  46.954  1.00 25.47  ? 316  LYS A O     1 
ATOM   5768  C  CB    . LYS C 2 316 ? 28.019  51.677  48.924  1.00 28.40  ? 316  LYS A CB    1 
ATOM   5769  C  CG    . LYS C 2 316 ? 26.967  51.408  47.868  1.00 51.91  ? 316  LYS A CG    1 
ATOM   5770  C  CD    . LYS C 2 316 ? 25.818  50.549  48.377  1.00 47.97  ? 316  LYS A CD    1 
ATOM   5771  C  CE    . LYS C 2 316 ? 24.766  50.344  47.283  1.00 50.43  ? 316  LYS A CE    1 
ATOM   5772  N  NZ    . LYS C 2 316 ? 23.621  49.496  47.758  1.00 51.39  ? 316  LYS A NZ    1 
ATOM   5773  N  N     . TYR C 2 317 ? 31.139  51.552  48.082  1.00 30.21  ? 317  TYR A N     1 
ATOM   5774  C  CA    . TYR C 2 317 ? 32.155  51.673  47.029  1.00 24.04  ? 317  TYR A CA    1 
ATOM   5775  C  C     . TYR C 2 317 ? 33.023  50.436  47.052  1.00 27.25  ? 317  TYR A C     1 
ATOM   5776  O  O     . TYR C 2 317 ? 33.342  49.869  46.011  1.00 31.97  ? 317  TYR A O     1 
ATOM   5777  C  CB    . TYR C 2 317 ? 33.025  52.917  47.231  1.00 26.14  ? 317  TYR A CB    1 
ATOM   5778  C  CG    . TYR C 2 317 ? 32.531  54.157  46.507  1.00 27.96  ? 317  TYR A CG    1 
ATOM   5779  C  CD1   . TYR C 2 317 ? 33.193  54.642  45.381  1.00 24.35  ? 317  TYR A CD1   1 
ATOM   5780  C  CD2   . TYR C 2 317 ? 31.349  54.784  46.885  1.00 29.09  ? 317  TYR A CD2   1 
ATOM   5781  C  CE1   . TYR C 2 317 ? 32.690  55.698  44.647  1.00 20.60  ? 317  TYR A CE1   1 
ATOM   5782  C  CE2   . TYR C 2 317 ? 30.827  55.861  46.137  1.00 33.15  ? 317  TYR A CE2   1 
ATOM   5783  C  CZ    . TYR C 2 317 ? 31.510  56.297  45.016  1.00 20.75  ? 317  TYR A CZ    1 
ATOM   5784  O  OH    . TYR C 2 317 ? 30.958  57.275  44.221  1.00 25.60  ? 317  TYR A OH    1 
ATOM   5785  N  N     . ILE C 2 318 ? 33.367  49.991  48.253  1.00 27.07  ? 318  ILE A N     1 
ATOM   5786  C  CA    . ILE C 2 318 ? 34.204  48.819  48.434  1.00 23.16  ? 318  ILE A CA    1 
ATOM   5787  C  C     . ILE C 2 318 ? 33.562  47.582  47.824  1.00 26.78  ? 318  ILE A C     1 
ATOM   5788  O  O     . ILE C 2 318 ? 34.246  46.749  47.241  1.00 25.04  ? 318  ILE A O     1 
ATOM   5789  C  CB    . ILE C 2 318 ? 34.447  48.544  49.932  1.00 22.56  ? 318  ILE A CB    1 
ATOM   5790  C  CG1   . ILE C 2 318 ? 35.452  49.567  50.455  1.00 25.02  ? 318  ILE A CG1   1 
ATOM   5791  C  CG2   . ILE C 2 318 ? 34.928  47.075  50.164  1.00 16.73  ? 318  ILE A CG2   1 
ATOM   5792  C  CD1   . ILE C 2 318 ? 35.550  49.637  51.964  1.00 29.77  ? 318  ILE A CD1   1 
ATOM   5793  N  N     . ARG C 2 319 ? 32.250  47.466  47.929  1.00 22.16  ? 319  ARG A N     1 
ATOM   5794  C  CA    . ARG C 2 319 ? 31.636  46.273  47.411  1.00 35.09  ? 319  ARG A CA    1 
ATOM   5795  C  C     . ARG C 2 319 ? 31.010  46.357  46.009  1.00 37.53  ? 319  ARG A C     1 
ATOM   5796  O  O     . ARG C 2 319 ? 30.940  45.349  45.319  1.00 40.39  ? 319  ARG A O     1 
ATOM   5797  C  CB    . ARG C 2 319 ? 30.659  45.713  48.476  1.00 27.36  ? 319  ARG A CB    1 
ATOM   5798  C  CG    . ARG C 2 319 ? 29.242  46.200  48.443  1.00 45.86  ? 319  ARG A CG    1 
ATOM   5799  C  CD    . ARG C 2 319 ? 28.439  45.497  49.563  1.00 47.99  ? 319  ARG A CD    1 
ATOM   5800  N  NE    . ARG C 2 319 ? 28.951  45.899  50.858  1.00 30.19  ? 319  ARG A NE    1 
ATOM   5801  C  CZ    . ARG C 2 319 ? 28.485  46.929  51.566  1.00 34.27  ? 319  ARG A CZ    1 
ATOM   5802  N  NH1   . ARG C 2 319 ? 29.045  47.223  52.733  1.00 27.54  ? 319  ARG A NH1   1 
ATOM   5803  N  NH2   . ARG C 2 319 ? 27.441  47.646  51.142  1.00 23.44  ? 319  ARG A NH2   1 
ATOM   5804  N  N     . GLU C 2 320 ? 30.635  47.553  45.557  1.00 38.39  ? 320  GLU A N     1 
ATOM   5805  C  CA    . GLU C 2 320 ? 29.999  47.698  44.253  1.00 30.03  ? 320  GLU A CA    1 
ATOM   5806  C  C     . GLU C 2 320 ? 30.648  48.597  43.221  1.00 35.87  ? 320  GLU A C     1 
ATOM   5807  O  O     . GLU C 2 320 ? 30.294  48.510  42.054  1.00 40.05  ? 320  GLU A O     1 
ATOM   5808  C  CB    . GLU C 2 320 ? 28.563  48.182  44.424  1.00 25.68  ? 320  GLU A CB    1 
ATOM   5809  C  CG    . GLU C 2 320 ? 27.710  47.318  45.345  1.00 33.49  ? 320  GLU A CG    1 
ATOM   5810  C  CD    . GLU C 2 320 ? 26.259  47.787  45.426  1.00 42.81  ? 320  GLU A CD    1 
ATOM   5811  O  OE1   . GLU C 2 320 ? 25.596  47.518  46.462  1.00 51.13  ? 320  GLU A OE1   1 
ATOM   5812  O  OE2   . GLU C 2 320 ? 25.779  48.419  44.460  1.00 44.59  ? 320  GLU A OE2   1 
ATOM   5813  N  N     . VAL C 2 321 ? 31.569  49.472  43.612  1.00 32.84  ? 321  VAL A N     1 
ATOM   5814  C  CA    . VAL C 2 321 ? 32.163  50.377  42.628  1.00 22.67  ? 321  VAL A CA    1 
ATOM   5815  C  C     . VAL C 2 321 ? 33.575  50.034  42.206  1.00 24.79  ? 321  VAL A C     1 
ATOM   5816  O  O     . VAL C 2 321 ? 33.890  50.060  41.031  1.00 29.23  ? 321  VAL A O     1 
ATOM   5817  C  CB    . VAL C 2 321 ? 32.163  51.845  43.135  1.00 28.69  ? 321  VAL A CB    1 
ATOM   5818  C  CG1   . VAL C 2 321 ? 32.762  52.790  42.056  1.00 25.69  ? 321  VAL A CG1   1 
ATOM   5819  C  CG2   . VAL C 2 321 ? 30.753  52.276  43.452  1.00 30.87  ? 321  VAL A CG2   1 
ATOM   5820  N  N     . LEU C 2 322 ? 34.437  49.766  43.175  1.00 26.57  ? 322  LEU A N     1 
ATOM   5821  C  CA    . LEU C 2 322 ? 35.793  49.399  42.888  1.00 31.43  ? 322  LEU A CA    1 
ATOM   5822  C  C     . LEU C 2 322 ? 35.767  47.925  42.522  1.00 34.44  ? 322  LEU A C     1 
ATOM   5823  O  O     . LEU C 2 322 ? 34.827  47.214  42.869  1.00 37.46  ? 322  LEU A O     1 
ATOM   5824  C  CB    . LEU C 2 322 ? 36.678  49.599  44.118  1.00 24.14  ? 322  LEU A CB    1 
ATOM   5825  C  CG    . LEU C 2 322 ? 36.771  51.018  44.673  1.00 39.79  ? 322  LEU A CG    1 
ATOM   5826  C  CD1   . LEU C 2 322 ? 38.125  51.205  45.385  1.00 38.85  ? 322  LEU A CD1   1 
ATOM   5827  C  CD2   . LEU C 2 322 ? 36.643  52.016  43.532  1.00 32.55  ? 322  LEU A CD2   1 
ATOM   5828  N  N     . SER C 2 323 ? 36.796  47.483  41.811  1.00 30.55  ? 323  SER A N     1 
ATOM   5829  C  CA    . SER C 2 323 ? 36.954  46.087  41.442  1.00 39.37  ? 323  SER A CA    1 
ATOM   5830  C  C     . SER C 2 323 ? 37.641  45.392  42.628  1.00 41.52  ? 323  SER A C     1 
ATOM   5831  O  O     . SER C 2 323 ? 38.202  46.049  43.525  1.00 36.59  ? 323  SER A O     1 
ATOM   5832  C  CB    . SER C 2 323 ? 37.866  45.979  40.227  1.00 36.85  ? 323  SER A CB    1 
ATOM   5833  O  OG    . SER C 2 323 ? 39.170  46.458  40.559  1.00 36.07  ? 323  SER A OG    1 
ATOM   5834  N  N     . LEU C 2 324 ? 37.616  44.066  42.604  1.00 40.97  ? 324  LEU A N     1 
ATOM   5835  C  CA    . LEU C 2 324 ? 38.245  43.253  43.634  1.00 41.46  ? 324  LEU A CA    1 
ATOM   5836  C  C     . LEU C 2 324 ? 39.729  43.612  43.777  1.00 40.75  ? 324  LEU A C     1 
ATOM   5837  O  O     . LEU C 2 324 ? 40.263  43.787  44.884  1.00 41.34  ? 324  LEU A O     1 
ATOM   5838  C  CB    . LEU C 2 324 ? 38.097  41.769  43.262  1.00 34.48  ? 324  LEU A CB    1 
ATOM   5839  C  CG    . LEU C 2 324 ? 38.721  40.736  44.211  1.00 44.60  ? 324  LEU A CG    1 
ATOM   5840  C  CD1   . LEU C 2 324 ? 38.373  41.091  45.662  1.00 31.44  ? 324  LEU A CD1   1 
ATOM   5841  C  CD2   . LEU C 2 324 ? 38.223  39.316  43.849  1.00 34.47  ? 324  LEU A CD2   1 
ATOM   5842  N  N     . GLU C 2 325 ? 40.388  43.718  42.636  1.00 37.20  ? 325  GLU A N     1 
ATOM   5843  C  CA    . GLU C 2 325 ? 41.802  44.021  42.597  1.00 36.54  ? 325  GLU A CA    1 
ATOM   5844  C  C     . GLU C 2 325 ? 42.111  45.407  43.160  1.00 35.67  ? 325  GLU A C     1 
ATOM   5845  O  O     . GLU C 2 325 ? 43.126  45.597  43.841  1.00 36.35  ? 325  GLU A O     1 
ATOM   5846  C  CB    . GLU C 2 325 ? 42.301  43.879  41.153  1.00 43.29  ? 325  GLU A CB    1 
ATOM   5847  C  CG    . GLU C 2 325 ? 42.121  42.467  40.545  1.00 36.18  ? 325  GLU A CG    1 
ATOM   5848  C  CD    . GLU C 2 325 ? 40.707  42.137  40.010  1.00 47.34  ? 325  GLU A CD    1 
ATOM   5849  O  OE1   . GLU C 2 325 ? 40.574  41.070  39.375  1.00 48.99  ? 325  GLU A OE1   1 
ATOM   5850  O  OE2   . GLU C 2 325 ? 39.730  42.899  40.210  1.00 44.04  ? 325  GLU A OE2   1 
ATOM   5851  N  N     . GLU C 2 326 ? 41.249  46.380  42.885  1.00 35.54  ? 326  GLU A N     1 
ATOM   5852  C  CA    . GLU C 2 326 ? 41.486  47.726  43.415  1.00 39.14  ? 326  GLU A CA    1 
ATOM   5853  C  C     . GLU C 2 326 ? 41.371  47.711  44.921  1.00 36.26  ? 326  GLU A C     1 
ATOM   5854  O  O     . GLU C 2 326 ? 42.179  48.355  45.603  1.00 28.13  ? 326  GLU A O     1 
ATOM   5855  C  CB    . GLU C 2 326 ? 40.510  48.768  42.829  1.00 44.51  ? 326  GLU A CB    1 
ATOM   5856  C  CG    . GLU C 2 326 ? 40.944  49.303  41.463  1.00 57.77  ? 326  GLU A CG    1 
ATOM   5857  C  CD    . GLU C 2 326 ? 39.985  50.329  40.864  1.00 71.27  ? 326  GLU A CD    1 
ATOM   5858  O  OE1   . GLU C 2 326 ? 38.799  49.973  40.610  1.00 56.48  ? 326  GLU A OE1   1 
ATOM   5859  O  OE2   . GLU C 2 326 ? 40.435  51.491  40.642  1.00 73.06  ? 326  GLU A OE2   1 
ATOM   5860  N  N     . VAL C 2 327 ? 40.396  46.964  45.451  1.00 24.70  ? 327  VAL A N     1 
ATOM   5861  C  CA    . VAL C 2 327 ? 40.255  46.916  46.896  1.00 26.95  ? 327  VAL A CA    1 
ATOM   5862  C  C     . VAL C 2 327 ? 41.475  46.254  47.527  1.00 31.73  ? 327  VAL A C     1 
ATOM   5863  O  O     . VAL C 2 327 ? 41.972  46.694  48.575  1.00 38.54  ? 327  VAL A O     1 
ATOM   5864  C  CB    . VAL C 2 327 ? 38.992  46.163  47.328  1.00 31.06  ? 327  VAL A CB    1 
ATOM   5865  C  CG1   . VAL C 2 327 ? 38.922  46.110  48.860  1.00 23.34  ? 327  VAL A CG1   1 
ATOM   5866  C  CG2   . VAL C 2 327 ? 37.765  46.868  46.771  1.00 22.50  ? 327  VAL A CG2   1 
ATOM   5867  N  N     . ALA C 2 328 ? 41.978  45.213  46.881  1.00 26.19  ? 328  ALA A N     1 
ATOM   5868  C  CA    . ALA C 2 328 ? 43.151  44.515  47.400  1.00 31.38  ? 328  ALA A CA    1 
ATOM   5869  C  C     . ALA C 2 328 ? 44.372  45.440  47.431  1.00 35.89  ? 328  ALA A C     1 
ATOM   5870  O  O     . ALA C 2 328 ? 45.165  45.413  48.384  1.00 32.84  ? 328  ALA A O     1 
ATOM   5871  C  CB    . ALA C 2 328 ? 43.452  43.265  46.552  1.00 25.86  ? 328  ALA A CB    1 
ATOM   5872  N  N     . GLU C 2 329 ? 44.533  46.255  46.396  1.00 27.44  ? 329  GLU A N     1 
ATOM   5873  C  CA    . GLU C 2 329 ? 45.669  47.163  46.393  1.00 37.74  ? 329  GLU A CA    1 
ATOM   5874  C  C     . GLU C 2 329 ? 45.587  48.178  47.536  1.00 37.61  ? 329  GLU A C     1 
ATOM   5875  O  O     . GLU C 2 329 ? 46.572  48.384  48.257  1.00 40.65  ? 329  GLU A O     1 
ATOM   5876  C  CB    . GLU C 2 329 ? 45.775  47.901  45.048  1.00 28.66  ? 329  GLU A CB    1 
ATOM   5877  C  CG    . GLU C 2 329 ? 47.065  48.656  44.869  1.00 44.29  ? 329  GLU A CG    1 
ATOM   5878  C  CD    . GLU C 2 329 ? 48.304  47.751  44.983  1.00 57.75  ? 329  GLU A CD    1 
ATOM   5879  O  OE1   . GLU C 2 329 ? 49.402  48.267  45.330  1.00 52.53  ? 329  GLU A OE1   1 
ATOM   5880  O  OE2   . GLU C 2 329 ? 48.182  46.530  44.716  1.00 54.61  ? 329  GLU A OE2   1 
ATOM   5881  N  N     . ARG C 2 330 ? 44.407  48.776  47.720  1.00 30.63  ? 330  ARG A N     1 
ATOM   5882  C  CA    . ARG C 2 330 ? 44.198  49.809  48.739  1.00 29.76  ? 330  ARG A CA    1 
ATOM   5883  C  C     . ARG C 2 330 ? 44.225  49.315  50.169  1.00 31.82  ? 330  ARG A C     1 
ATOM   5884  O  O     . ARG C 2 330 ? 44.395  50.081  51.118  1.00 36.26  ? 330  ARG A O     1 
ATOM   5885  C  CB    . ARG C 2 330 ? 42.864  50.521  48.495  1.00 33.39  ? 330  ARG A CB    1 
ATOM   5886  C  CG    . ARG C 2 330 ? 42.858  51.433  47.290  1.00 27.81  ? 330  ARG A CG    1 
ATOM   5887  C  CD    . ARG C 2 330 ? 41.445  51.752  46.928  1.00 25.21  ? 330  ARG A CD    1 
ATOM   5888  N  NE    . ARG C 2 330 ? 41.321  52.372  45.616  1.00 36.07  ? 330  ARG A NE    1 
ATOM   5889  C  CZ    . ARG C 2 330 ? 40.790  53.572  45.401  1.00 36.72  ? 330  ARG A CZ    1 
ATOM   5890  N  NH1   . ARG C 2 330 ? 40.343  54.313  46.413  1.00 29.15  ? 330  ARG A NH1   1 
ATOM   5891  N  NH2   . ARG C 2 330 ? 40.652  54.007  44.162  1.00 29.36  ? 330  ARG A NH2   1 
ATOM   5892  N  N     . VAL C 2 331 ? 44.034  48.027  50.328  1.00 29.27  ? 331  VAL A N     1 
ATOM   5893  C  CA    . VAL C 2 331 ? 44.032  47.454  51.651  1.00 34.37  ? 331  VAL A CA    1 
ATOM   5894  C  C     . VAL C 2 331 ? 45.469  47.231  52.181  1.00 38.44  ? 331  VAL A C     1 
ATOM   5895  O  O     . VAL C 2 331 ? 45.680  47.130  53.395  1.00 37.60  ? 331  VAL A O     1 
ATOM   5896  C  CB    . VAL C 2 331 ? 43.189  46.139  51.604  1.00 37.15  ? 331  VAL A CB    1 
ATOM   5897  C  CG1   . VAL C 2 331 ? 44.060  44.924  51.723  1.00 33.87  ? 331  VAL A CG1   1 
ATOM   5898  C  CG2   . VAL C 2 331 ? 42.102  46.198  52.631  1.00 27.94  ? 331  VAL A CG2   1 
ATOM   5899  N  N     . LYS C 2 332 ? 46.455  47.202  51.278  1.00 33.50  ? 332  LYS A N     1 
ATOM   5900  C  CA    . LYS C 2 332 ? 47.857  46.956  51.652  1.00 32.91  ? 332  LYS A CA    1 
ATOM   5901  C  C     . LYS C 2 332 ? 48.463  47.890  52.688  1.00 37.56  ? 332  LYS A C     1 
ATOM   5902  O  O     . LYS C 2 332 ? 49.096  47.454  53.647  1.00 35.61  ? 332  LYS A O     1 
ATOM   5903  C  CB    . LYS C 2 332 ? 48.730  46.947  50.394  1.00 33.51  ? 332  LYS A CB    1 
ATOM   5904  C  CG    . LYS C 2 332 ? 48.515  45.693  49.520  1.00 29.63  ? 332  LYS A CG    1 
ATOM   5905  C  CD    . LYS C 2 332 ? 49.332  45.727  48.230  1.00 34.70  ? 332  LYS A CD    1 
ATOM   5906  C  CE    . LYS C 2 332 ? 49.056  44.492  47.397  1.00 34.10  ? 332  LYS A CE    1 
ATOM   5907  N  NZ    . LYS C 2 332 ? 49.610  44.555  46.024  1.00 30.42  ? 332  LYS A NZ    1 
ATOM   5908  N  N     . PRO C 2 333 ? 48.280  49.196  52.517  1.00 36.87  ? 333  PRO A N     1 
ATOM   5909  C  CA    . PRO C 2 333 ? 48.867  50.086  53.517  1.00 36.99  ? 333  PRO A CA    1 
ATOM   5910  C  C     . PRO C 2 333 ? 48.368  49.801  54.927  1.00 36.29  ? 333  PRO A C     1 
ATOM   5911  O  O     . PRO C 2 333 ? 49.108  49.966  55.900  1.00 41.83  ? 333  PRO A O     1 
ATOM   5912  C  CB    . PRO C 2 333 ? 48.431  51.465  53.037  1.00 33.47  ? 333  PRO A CB    1 
ATOM   5913  C  CG    . PRO C 2 333 ? 48.265  51.282  51.581  1.00 41.34  ? 333  PRO A CG    1 
ATOM   5914  C  CD    . PRO C 2 333 ? 47.599  49.952  51.462  1.00 30.69  ? 333  PRO A CD    1 
ATOM   5915  N  N     . PHE C 2 334 ? 47.107  49.387  55.044  1.00 31.23  ? 334  PHE A N     1 
ATOM   5916  C  CA    . PHE C 2 334 ? 46.519  49.140  56.352  1.00 27.20  ? 334  PHE A CA    1 
ATOM   5917  C  C     . PHE C 2 334 ? 47.009  47.833  56.917  1.00 40.03  ? 334  PHE A C     1 
ATOM   5918  O  O     . PHE C 2 334 ? 47.133  47.673  58.137  1.00 40.83  ? 334  PHE A O     1 
ATOM   5919  C  CB    . PHE C 2 334 ? 44.988  49.215  56.269  1.00 21.78  ? 334  PHE A CB    1 
ATOM   5920  C  CG    . PHE C 2 334 ? 44.495  50.601  55.930  1.00 22.18  ? 334  PHE A CG    1 
ATOM   5921  C  CD1   . PHE C 2 334 ? 44.217  51.515  56.941  1.00 15.41  ? 334  PHE A CD1   1 
ATOM   5922  C  CD2   . PHE C 2 334 ? 44.484  51.039  54.611  1.00 21.19  ? 334  PHE A CD2   1 
ATOM   5923  C  CE1   . PHE C 2 334 ? 43.957  52.825  56.664  1.00 14.29  ? 334  PHE A CE1   1 
ATOM   5924  C  CE2   . PHE C 2 334 ? 44.223  52.367  54.300  1.00 24.30  ? 334  PHE A CE2   1 
ATOM   5925  C  CZ    . PHE C 2 334 ? 43.965  53.269  55.337  1.00 29.86  ? 334  PHE A CZ    1 
ATOM   5926  N  N     . LEU C 2 335 ? 47.300  46.885  56.034  1.00 42.23  ? 335  LEU A N     1 
ATOM   5927  C  CA    . LEU C 2 335 ? 47.862  45.617  56.492  1.00 38.66  ? 335  LEU A CA    1 
ATOM   5928  C  C     . LEU C 2 335 ? 49.259  45.924  56.992  1.00 34.89  ? 335  LEU A C     1 
ATOM   5929  O  O     . LEU C 2 335 ? 49.648  45.449  58.047  1.00 29.68  ? 335  LEU A O     1 
ATOM   5930  C  CB    . LEU C 2 335 ? 47.954  44.604  55.361  1.00 29.71  ? 335  LEU A CB    1 
ATOM   5931  C  CG    . LEU C 2 335 ? 46.653  43.874  55.077  1.00 32.31  ? 335  LEU A CG    1 
ATOM   5932  C  CD1   . LEU C 2 335 ? 46.734  43.177  53.751  1.00 30.35  ? 335  LEU A CD1   1 
ATOM   5933  C  CD2   . LEU C 2 335 ? 46.386  42.900  56.230  1.00 37.16  ? 335  LEU A CD2   1 
ATOM   5934  N  N     . ARG C 2 336 ? 50.004  46.728  56.233  1.00 29.66  ? 336  ARG A N     1 
ATOM   5935  C  CA    . ARG C 2 336 ? 51.361  47.072  56.626  1.00 38.07  ? 336  ARG A CA    1 
ATOM   5936  C  C     . ARG C 2 336 ? 51.341  47.755  57.986  1.00 44.24  ? 336  ARG A C     1 
ATOM   5937  O  O     . ARG C 2 336 ? 52.066  47.359  58.905  1.00 45.21  ? 336  ARG A O     1 
ATOM   5938  C  CB    . ARG C 2 336 ? 52.022  47.989  55.578  1.00 36.74  ? 336  ARG A CB    1 
ATOM   5939  C  CG    . ARG C 2 336 ? 52.804  47.254  54.494  1.00 39.24  ? 336  ARG A CG    1 
ATOM   5940  C  CD    . ARG C 2 336 ? 53.270  48.187  53.355  1.00 60.73  ? 336  ARG A CD    1 
ATOM   5941  N  NE    . ARG C 2 336 ? 52.318  48.307  52.235  1.00 69.99  ? 336  ARG A NE    1 
ATOM   5942  C  CZ    . ARG C 2 336 ? 51.811  49.459  51.782  1.00 80.25  ? 336  ARG A CZ    1 
ATOM   5943  N  NH1   . ARG C 2 336 ? 52.149  50.617  52.352  1.00 84.13  ? 336  ARG A NH1   1 
ATOM   5944  N  NH2   . ARG C 2 336 ? 50.976  49.463  50.743  1.00 78.36  ? 336  ARG A NH2   1 
ATOM   5945  N  N     . GLU C 2 337 ? 50.488  48.768  58.109  1.00 46.92  ? 337  GLU A N     1 
ATOM   5946  C  CA    . GLU C 2 337 ? 50.353  49.531  59.340  1.00 49.52  ? 337  GLU A CA    1 
ATOM   5947  C  C     . GLU C 2 337 ? 50.002  48.643  60.535  1.00 48.12  ? 337  GLU A C     1 
ATOM   5948  O  O     . GLU C 2 337 ? 50.374  48.934  61.677  1.00 50.56  ? 337  GLU A O     1 
ATOM   5949  C  CB    . GLU C 2 337 ? 49.276  50.608  59.167  1.00 54.92  ? 337  GLU A CB    1 
ATOM   5950  C  CG    . GLU C 2 337 ? 48.928  51.332  60.464  1.00 69.45  ? 337  GLU A CG    1 
ATOM   5951  C  CD    . GLU C 2 337 ? 47.574  52.023  60.412  1.00 81.38  ? 337  GLU A CD    1 
ATOM   5952  O  OE1   . GLU C 2 337 ? 47.013  52.326  61.495  1.00 78.43  ? 337  GLU A OE1   1 
ATOM   5953  O  OE2   . GLU C 2 337 ? 47.072  52.263  59.290  1.00 88.82  ? 337  GLU A OE2   1 
ATOM   5954  N  N     . ALA C 2 338 ? 49.273  47.567  60.272  1.00 46.03  ? 338  ALA A N     1 
ATOM   5955  C  CA    . ALA C 2 338 ? 48.868  46.633  61.323  1.00 49.26  ? 338  ALA A CA    1 
ATOM   5956  C  C     . ALA C 2 338 ? 49.993  45.635  61.609  1.00 54.73  ? 338  ALA A C     1 
ATOM   5957  O  O     . ALA C 2 338 ? 49.887  44.799  62.515  1.00 58.47  ? 338  ALA A O     1 
ATOM   5958  C  CB    . ALA C 2 338 ? 47.605  45.883  60.898  1.00 37.39  ? 338  ALA A CB    1 
ATOM   5959  N  N     . GLY C 2 339 ? 51.065  45.724  60.822  1.00 50.50  ? 339  GLY A N     1 
ATOM   5960  C  CA    . GLY C 2 339 ? 52.194  44.837  61.008  1.00 49.87  ? 339  GLY A CA    1 
ATOM   5961  C  C     . GLY C 2 339 ? 51.980  43.446  60.445  1.00 50.50  ? 339  GLY A C     1 
ATOM   5962  O  O     . GLY C 2 339 ? 52.653  42.498  60.844  1.00 55.35  ? 339  GLY A O     1 
ATOM   5963  N  N     . LEU C 2 340 ? 51.054  43.318  59.505  1.00 45.85  ? 340  LEU A N     1 
ATOM   5964  C  CA    . LEU C 2 340 ? 50.766  42.030  58.905  1.00 35.87  ? 340  LEU A CA    1 
ATOM   5965  C  C     . LEU C 2 340 ? 51.263  41.966  57.467  1.00 40.00  ? 340  LEU A C     1 
ATOM   5966  O  O     . LEU C 2 340 ? 51.417  43.002  56.805  1.00 40.43  ? 340  LEU A O     1 
ATOM   5967  C  CB    . LEU C 2 340 ? 49.269  41.789  58.917  1.00 33.37  ? 340  LEU A CB    1 
ATOM   5968  C  CG    . LEU C 2 340 ? 48.526  41.829  60.246  1.00 32.98  ? 340  LEU A CG    1 
ATOM   5969  C  CD1   . LEU C 2 340 ? 47.054  41.778  59.916  1.00 25.55  ? 340  LEU A CD1   1 
ATOM   5970  C  CD2   . LEU C 2 340 ? 48.909  40.646  61.145  1.00 33.30  ? 340  LEU A CD2   1 
ATOM   5971  N  N     . SER C 2 341 ? 51.539  40.754  56.989  1.00 28.73  ? 341  SER A N     1 
ATOM   5972  C  CA    . SER C 2 341 ? 51.958  40.585  55.603  1.00 39.08  ? 341  SER A CA    1 
ATOM   5973  C  C     . SER C 2 341 ? 51.091  39.515  54.938  1.00 38.94  ? 341  SER A C     1 
ATOM   5974  O  O     . SER C 2 341 ? 50.423  38.727  55.605  1.00 33.76  ? 341  SER A O     1 
ATOM   5975  C  CB    . SER C 2 341 ? 53.431  40.172  55.511  1.00 43.59  ? 341  SER A CB    1 
ATOM   5976  O  OG    . SER C 2 341 ? 53.580  38.794  55.801  1.00 56.55  ? 341  SER A OG    1 
ATOM   5977  N  N     . TRP C 2 342 ? 51.102  39.495  53.617  1.00 39.88  ? 342  TRP A N     1 
ATOM   5978  C  CA    . TRP C 2 342 ? 50.326  38.515  52.878  1.00 44.22  ? 342  TRP A CA    1 
ATOM   5979  C  C     . TRP C 2 342 ? 51.319  37.638  52.113  1.00 48.47  ? 342  TRP A C     1 
ATOM   5980  O  O     . TRP C 2 342 ? 52.353  38.127  51.673  1.00 40.77  ? 342  TRP A O     1 
ATOM   5981  C  CB    . TRP C 2 342 ? 49.353  39.239  51.940  1.00 36.29  ? 342  TRP A CB    1 
ATOM   5982  C  CG    . TRP C 2 342 ? 49.983  40.345  51.133  1.00 49.87  ? 342  TRP A CG    1 
ATOM   5983  C  CD1   . TRP C 2 342 ? 50.355  40.296  49.812  1.00 46.87  ? 342  TRP A CD1   1 
ATOM   5984  C  CD2   . TRP C 2 342 ? 50.325  41.663  51.593  1.00 42.52  ? 342  TRP A CD2   1 
ATOM   5985  N  NE1   . TRP C 2 342 ? 50.901  41.502  49.426  1.00 44.44  ? 342  TRP A NE1   1 
ATOM   5986  C  CE2   . TRP C 2 342 ? 50.897  42.356  50.497  1.00 35.46  ? 342  TRP A CE2   1 
ATOM   5987  C  CE3   . TRP C 2 342 ? 50.204  42.323  52.820  1.00 34.55  ? 342  TRP A CE3   1 
ATOM   5988  C  CZ2   . TRP C 2 342 ? 51.345  43.669  50.594  1.00 32.64  ? 342  TRP A CZ2   1 
ATOM   5989  C  CZ3   . TRP C 2 342 ? 50.653  43.632  52.915  1.00 39.29  ? 342  TRP A CZ3   1 
ATOM   5990  C  CH2   . TRP C 2 342 ? 51.217  44.291  51.804  1.00 37.58  ? 342  TRP A CH2   1 
ATOM   5991  N  N     . GLU C 2 343 ? 51.021  36.347  51.977  1.00 55.91  ? 343  GLU A N     1 
ATOM   5992  C  CA    . GLU C 2 343 ? 51.932  35.428  51.291  1.00 62.59  ? 343  GLU A CA    1 
ATOM   5993  C  C     . GLU C 2 343 ? 52.171  35.782  49.840  1.00 63.87  ? 343  GLU A C     1 
ATOM   5994  O  O     . GLU C 2 343 ? 53.291  35.679  49.358  1.00 65.48  ? 343  GLU A O     1 
ATOM   5995  C  CB    . GLU C 2 343 ? 51.400  34.002  51.293  1.00 73.95  ? 343  GLU A CB    1 
ATOM   5996  C  CG    . GLU C 2 343 ? 50.684  33.559  52.539  1.00 88.60  ? 343  GLU A CG    1 
ATOM   5997  C  CD    . GLU C 2 343 ? 50.193  32.136  52.394  1.00 90.11  ? 343  GLU A CD    1 
ATOM   5998  O  OE1   . GLU C 2 343 ? 51.040  31.216  52.387  1.00 97.01  ? 343  GLU A OE1   1 
ATOM   5999  O  OE2   . GLU C 2 343 ? 48.967  31.938  52.264  1.00 92.24  ? 343  GLU A OE2   1 
ATOM   6000  N  N     . SER C 2 344 ? 51.110  36.177  49.144  1.00 60.34  ? 344  SER A N     1 
ATOM   6001  C  CA    . SER C 2 344 ? 51.195  36.506  47.725  1.00 55.35  ? 344  SER A CA    1 
ATOM   6002  C  C     . SER C 2 344 ? 49.998  37.334  47.285  1.00 54.49  ? 344  SER A C     1 
ATOM   6003  O  O     . SER C 2 344 ? 49.055  37.534  48.044  1.00 60.40  ? 344  SER A O     1 
ATOM   6004  C  CB    . SER C 2 344 ? 51.189  35.228  46.905  1.00 48.83  ? 344  SER A CB    1 
ATOM   6005  O  OG    . SER C 2 344 ? 49.978  34.529  47.145  1.00 55.09  ? 344  SER A OG    1 
ATOM   6006  N  N     . GLU C 2 345 ? 50.027  37.798  46.044  1.00 47.25  ? 345  GLU A N     1 
ATOM   6007  C  CA    . GLU C 2 345 ? 48.917  38.585  45.526  1.00 47.10  ? 345  GLU A CA    1 
ATOM   6008  C  C     . GLU C 2 345 ? 47.684  37.702  45.493  1.00 44.21  ? 345  GLU A C     1 
ATOM   6009  O  O     . GLU C 2 345 ? 46.592  38.113  45.888  1.00 38.39  ? 345  GLU A O     1 
ATOM   6010  C  CB    . GLU C 2 345 ? 49.209  39.080  44.104  1.00 48.48  ? 345  GLU A CB    1 
ATOM   6011  C  CG    . GLU C 2 345 ? 50.304  40.148  44.007  1.00 52.40  ? 345  GLU A CG    1 
ATOM   6012  C  CD    . GLU C 2 345 ? 49.881  41.487  44.605  1.00 64.13  ? 345  GLU A CD    1 
ATOM   6013  O  OE1   . GLU C 2 345 ? 48.979  42.133  44.022  1.00 46.10  ? 345  GLU A OE1   1 
ATOM   6014  O  OE2   . GLU C 2 345 ? 50.452  41.887  45.657  1.00 64.65  ? 345  GLU A OE2   1 
ATOM   6015  N  N     . ALA C 2 346 ? 47.878  36.479  45.020  1.00 37.92  ? 346  ALA A N     1 
ATOM   6016  C  CA    . ALA C 2 346 ? 46.791  35.539  44.907  1.00 36.65  ? 346  ALA A CA    1 
ATOM   6017  C  C     . ALA C 2 346 ? 46.082  35.372  46.250  1.00 39.06  ? 346  ALA A C     1 
ATOM   6018  O  O     . ALA C 2 346 ? 44.852  35.426  46.334  1.00 35.97  ? 346  ALA A O     1 
ATOM   6019  C  CB    . ALA C 2 346 ? 47.321  34.201  44.407  1.00 32.44  ? 346  ALA A CB    1 
ATOM   6020  N  N     . TYR C 2 347 ? 46.864  35.204  47.305  1.00 39.00  ? 347  TYR A N     1 
ATOM   6021  C  CA    . TYR C 2 347 ? 46.291  35.004  48.629  1.00 40.47  ? 347  TYR A CA    1 
ATOM   6022  C  C     . TYR C 2 347 ? 45.541  36.245  49.113  1.00 37.25  ? 347  TYR A C     1 
ATOM   6023  O  O     . TYR C 2 347 ? 44.402  36.166  49.580  1.00 36.73  ? 347  TYR A O     1 
ATOM   6024  C  CB    . TYR C 2 347 ? 47.390  34.652  49.625  1.00 33.44  ? 347  TYR A CB    1 
ATOM   6025  C  CG    . TYR C 2 347 ? 46.851  34.269  50.975  1.00 45.63  ? 347  TYR A CG    1 
ATOM   6026  C  CD1   . TYR C 2 347 ? 46.418  32.968  51.224  1.00 41.21  ? 347  TYR A CD1   1 
ATOM   6027  C  CD2   . TYR C 2 347 ? 46.766  35.214  52.011  1.00 39.66  ? 347  TYR A CD2   1 
ATOM   6028  C  CE1   . TYR C 2 347 ? 45.919  32.605  52.466  1.00 40.64  ? 347  TYR A CE1   1 
ATOM   6029  C  CE2   . TYR C 2 347 ? 46.264  34.866  53.255  1.00 38.63  ? 347  TYR A CE2   1 
ATOM   6030  C  CZ    . TYR C 2 347 ? 45.839  33.550  53.480  1.00 47.05  ? 347  TYR A CZ    1 
ATOM   6031  O  OH    . TYR C 2 347 ? 45.329  33.177  54.709  1.00 39.59  ? 347  TYR A OH    1 
ATOM   6032  N  N     . LEU C 2 348 ? 46.184  37.397  49.003  1.00 30.15  ? 348  LEU A N     1 
ATOM   6033  C  CA    . LEU C 2 348 ? 45.555  38.633  49.435  1.00 34.24  ? 348  LEU A CA    1 
ATOM   6034  C  C     . LEU C 2 348 ? 44.221  38.852  48.705  1.00 33.42  ? 348  LEU A C     1 
ATOM   6035  O  O     . LEU C 2 348 ? 43.218  39.158  49.333  1.00 35.94  ? 348  LEU A O     1 
ATOM   6036  C  CB    . LEU C 2 348 ? 46.501  39.803  49.194  1.00 25.33  ? 348  LEU A CB    1 
ATOM   6037  C  CG    . LEU C 2 348 ? 45.925  41.199  49.403  1.00 31.18  ? 348  LEU A CG    1 
ATOM   6038  C  CD1   . LEU C 2 348 ? 45.423  41.342  50.838  1.00 21.40  ? 348  LEU A CD1   1 
ATOM   6039  C  CD2   . LEU C 2 348 ? 47.002  42.235  49.089  1.00 27.36  ? 348  LEU A CD2   1 
ATOM   6040  N  N     . ARG C 2 349 ? 44.210  38.653  47.389  1.00 36.56  ? 349  ARG A N     1 
ATOM   6041  C  CA    . ARG C 2 349 ? 42.996  38.857  46.595  1.00 37.63  ? 349  ARG A CA    1 
ATOM   6042  C  C     . ARG C 2 349 ? 41.854  37.952  47.073  1.00 32.13  ? 349  ARG A C     1 
ATOM   6043  O  O     . ARG C 2 349 ? 40.737  38.396  47.230  1.00 33.36  ? 349  ARG A O     1 
ATOM   6044  C  CB    . ARG C 2 349 ? 43.287  38.632  45.104  1.00 37.75  ? 349  ARG A CB    1 
ATOM   6045  C  CG    . ARG C 2 349 ? 42.082  38.849  44.185  1.00 37.29  ? 349  ARG A CG    1 
ATOM   6046  C  CD    . ARG C 2 349 ? 42.390  38.436  42.734  1.00 38.28  ? 349  ARG A CD    1 
ATOM   6047  N  NE    . ARG C 2 349 ? 43.465  39.242  42.144  1.00 53.42  ? 349  ARG A NE    1 
ATOM   6048  C  CZ    . ARG C 2 349 ? 44.135  38.910  41.039  1.00 49.99  ? 349  ARG A CZ    1 
ATOM   6049  N  NH1   . ARG C 2 349 ? 43.848  37.785  40.401  1.00 44.22  ? 349  ARG A NH1   1 
ATOM   6050  N  NH2   . ARG C 2 349 ? 45.086  39.708  40.563  1.00 42.51  ? 349  ARG A NH2   1 
ATOM   6051  N  N     . ARG C 2 350 ? 42.131  36.683  47.306  1.00 31.07  ? 350  ARG A N     1 
ATOM   6052  C  CA    . ARG C 2 350 ? 41.091  35.796  47.780  1.00 31.22  ? 350  ARG A CA    1 
ATOM   6053  C  C     . ARG C 2 350 ? 40.612  36.203  49.180  1.00 31.06  ? 350  ARG A C     1 
ATOM   6054  O  O     . ARG C 2 350 ? 39.416  36.164  49.465  1.00 33.43  ? 350  ARG A O     1 
ATOM   6055  C  CB    . ARG C 2 350 ? 41.600  34.360  47.787  1.00 31.19  ? 350  ARG A CB    1 
ATOM   6056  C  CG    . ARG C 2 350 ? 40.554  33.354  48.286  1.00 44.50  ? 350  ARG A CG    1 
ATOM   6057  C  CD    . ARG C 2 350 ? 39.185  33.541  47.635  1.00 31.93  ? 350  ARG A CD    1 
ATOM   6058  N  NE    . ARG C 2 350 ? 38.311  32.425  47.981  1.00 37.34  ? 350  ARG A NE    1 
ATOM   6059  C  CZ    . ARG C 2 350 ? 37.176  32.132  47.351  1.00 45.34  ? 350  ARG A CZ    1 
ATOM   6060  N  NH1   . ARG C 2 350 ? 36.765  32.872  46.326  1.00 44.84  ? 350  ARG A NH1   1 
ATOM   6061  N  NH2   . ARG C 2 350 ? 36.448  31.096  47.750  1.00 41.27  ? 350  ARG A NH2   1 
ATOM   6062  N  N     . ALA C 2 351 ? 41.539  36.602  50.046  1.00 25.89  ? 351  ALA A N     1 
ATOM   6063  C  CA    . ALA C 2 351 ? 41.167  37.035  51.386  1.00 24.39  ? 351  ALA A CA    1 
ATOM   6064  C  C     . ALA C 2 351 ? 40.262  38.267  51.305  1.00 25.82  ? 351  ALA A C     1 
ATOM   6065  O  O     . ALA C 2 351 ? 39.203  38.330  51.960  1.00 33.62  ? 351  ALA A O     1 
ATOM   6066  C  CB    . ALA C 2 351 ? 42.397  37.341  52.203  1.00 25.20  ? 351  ALA A CB    1 
ATOM   6067  N  N     . VAL C 2 352 ? 40.652  39.234  50.486  1.00 18.46  ? 352  VAL A N     1 
ATOM   6068  C  CA    . VAL C 2 352 ? 39.839  40.435  50.321  1.00 22.57  ? 352  VAL A CA    1 
ATOM   6069  C  C     . VAL C 2 352 ? 38.468  40.093  49.754  1.00 18.85  ? 352  VAL A C     1 
ATOM   6070  O  O     . VAL C 2 352 ? 37.459  40.694  50.122  1.00 26.19  ? 352  VAL A O     1 
ATOM   6071  C  CB    . VAL C 2 352 ? 40.529  41.452  49.403  1.00 27.94  ? 352  VAL A CB    1 
ATOM   6072  C  CG1   . VAL C 2 352 ? 39.544  42.541  48.943  1.00 26.54  ? 352  VAL A CG1   1 
ATOM   6073  C  CG2   . VAL C 2 352 ? 41.672  42.093  50.158  1.00 29.15  ? 352  VAL A CG2   1 
ATOM   6074  N  N     . GLU C 2 353 ? 38.421  39.110  48.873  1.00 20.41  ? 353  GLU A N     1 
ATOM   6075  C  CA    . GLU C 2 353 ? 37.160  38.719  48.276  1.00 23.35  ? 353  GLU A CA    1 
ATOM   6076  C  C     . GLU C 2 353 ? 36.201  38.128  49.325  1.00 25.91  ? 353  GLU A C     1 
ATOM   6077  O  O     . GLU C 2 353 ? 35.009  38.423  49.328  1.00 29.57  ? 353  GLU A O     1 
ATOM   6078  C  CB    . GLU C 2 353 ? 37.421  37.723  47.158  1.00 28.44  ? 353  GLU A CB    1 
ATOM   6079  C  CG    . GLU C 2 353 ? 36.158  37.159  46.522  1.00 26.62  ? 353  GLU A CG    1 
ATOM   6080  C  CD    . GLU C 2 353 ? 36.469  36.398  45.258  1.00 41.93  ? 353  GLU A CD    1 
ATOM   6081  O  OE1   . GLU C 2 353 ? 35.651  36.490  44.318  1.00 53.88  ? 353  GLU A OE1   1 
ATOM   6082  O  OE2   . GLU C 2 353 ? 37.527  35.714  45.191  1.00 36.46  ? 353  GLU A OE2   1 
ATOM   6083  N  N     . LEU C 2 354 ? 36.722  37.295  50.214  1.00 25.44  ? 354  LEU A N     1 
ATOM   6084  C  CA    . LEU C 2 354 ? 35.897  36.680  51.255  1.00 21.54  ? 354  LEU A CA    1 
ATOM   6085  C  C     . LEU C 2 354 ? 35.384  37.733  52.242  1.00 22.15  ? 354  LEU A C     1 
ATOM   6086  O  O     . LEU C 2 354 ? 34.295  37.596  52.809  1.00 24.49  ? 354  LEU A O     1 
ATOM   6087  C  CB    . LEU C 2 354 ? 36.707  35.618  52.025  1.00 24.62  ? 354  LEU A CB    1 
ATOM   6088  C  CG    . LEU C 2 354 ? 37.235  34.366  51.300  1.00 37.70  ? 354  LEU A CG    1 
ATOM   6089  C  CD1   . LEU C 2 354 ? 38.031  33.505  52.271  1.00 35.22  ? 354  LEU A CD1   1 
ATOM   6090  C  CD2   . LEU C 2 354 ? 36.086  33.559  50.728  1.00 30.89  ? 354  LEU A CD2   1 
ATOM   6091  N  N     . MET C 2 355 ? 36.169  38.783  52.457  1.00 20.56  ? 355  MET A N     1 
ATOM   6092  C  CA    . MET C 2 355 ? 35.768  39.814  53.401  1.00 22.03  ? 355  MET A CA    1 
ATOM   6093  C  C     . MET C 2 355 ? 35.067  41.015  52.803  1.00 25.94  ? 355  MET A C     1 
ATOM   6094  O  O     . MET C 2 355 ? 34.556  41.843  53.552  1.00 21.35  ? 355  MET A O     1 
ATOM   6095  C  CB    . MET C 2 355 ? 36.966  40.328  54.198  1.00 21.41  ? 355  MET A CB    1 
ATOM   6096  C  CG    . MET C 2 355 ? 37.642  39.298  55.063  1.00 30.87  ? 355  MET A CG    1 
ATOM   6097  S  SD    . MET C 2 355 ? 36.658  38.752  56.481  1.00 34.96  ? 355  MET A SD    1 
ATOM   6098  C  CE    . MET C 2 355 ? 36.271  40.295  57.341  1.00 22.63  ? 355  MET A CE    1 
ATOM   6099  N  N     . ARG C 2 356 ? 35.029  41.118  51.476  1.00 28.59  ? 356  ARG A N     1 
ATOM   6100  C  CA    . ARG C 2 356 ? 34.410  42.279  50.839  1.00 31.90  ? 356  ARG A CA    1 
ATOM   6101  C  C     . ARG C 2 356 ? 33.119  42.786  51.464  1.00 32.04  ? 356  ARG A C     1 
ATOM   6102  O  O     . ARG C 2 356 ? 32.994  43.969  51.743  1.00 30.49  ? 356  ARG A O     1 
ATOM   6103  C  CB    . ARG C 2 356 ? 34.174  42.036  49.349  1.00 32.22  ? 356  ARG A CB    1 
ATOM   6104  C  CG    . ARG C 2 356 ? 35.142  42.844  48.512  1.00 35.55  ? 356  ARG A CG    1 
ATOM   6105  C  CD    . ARG C 2 356 ? 34.460  43.702  47.479  1.00 35.82  ? 356  ARG A CD    1 
ATOM   6106  N  NE    . ARG C 2 356 ? 34.431  43.056  46.175  1.00 37.97  ? 356  ARG A NE    1 
ATOM   6107  C  CZ    . ARG C 2 356 ? 34.417  43.703  45.018  1.00 35.66  ? 356  ARG A CZ    1 
ATOM   6108  N  NH1   . ARG C 2 356 ? 34.433  45.024  44.994  1.00 37.87  ? 356  ARG A NH1   1 
ATOM   6109  N  NH2   . ARG C 2 356 ? 34.378  43.024  43.881  1.00 41.54  ? 356  ARG A NH2   1 
ATOM   6110  N  N     . PRO C 2 357 ? 32.140  41.906  51.678  1.00 22.03  ? 357  PRO A N     1 
ATOM   6111  C  CA    . PRO C 2 357 ? 30.911  42.397  52.278  1.00 25.14  ? 357  PRO A CA    1 
ATOM   6112  C  C     . PRO C 2 357 ? 30.991  42.599  53.795  1.00 32.72  ? 357  PRO A C     1 
ATOM   6113  O  O     . PRO C 2 357 ? 29.992  42.908  54.426  1.00 35.90  ? 357  PRO A O     1 
ATOM   6114  C  CB    . PRO C 2 357 ? 29.912  41.317  51.917  1.00 30.35  ? 357  PRO A CB    1 
ATOM   6115  C  CG    . PRO C 2 357 ? 30.729  40.091  52.012  1.00 33.53  ? 357  PRO A CG    1 
ATOM   6116  C  CD    . PRO C 2 357 ? 32.041  40.479  51.341  1.00 24.66  ? 357  PRO A CD    1 
ATOM   6117  N  N     . ARG C 2 358 ? 32.163  42.437  54.391  1.00 31.81  ? 358  ARG A N     1 
ATOM   6118  C  CA    . ARG C 2 358 ? 32.244  42.581  55.833  1.00 26.47  ? 358  ARG A CA    1 
ATOM   6119  C  C     . ARG C 2 358 ? 33.038  43.755  56.420  1.00 29.77  ? 358  ARG A C     1 
ATOM   6120  O  O     . ARG C 2 358 ? 33.190  43.836  57.640  1.00 29.03  ? 358  ARG A O     1 
ATOM   6121  C  CB    . ARG C 2 358 ? 32.705  41.256  56.440  1.00 26.67  ? 358  ARG A CB    1 
ATOM   6122  C  CG    . ARG C 2 358 ? 31.794  40.110  56.029  1.00 28.14  ? 358  ARG A CG    1 
ATOM   6123  C  CD    . ARG C 2 358 ? 32.334  38.738  56.414  1.00 35.29  ? 358  ARG A CD    1 
ATOM   6124  N  NE    . ARG C 2 358 ? 31.316  37.695  56.261  1.00 34.80  ? 358  ARG A NE    1 
ATOM   6125  C  CZ    . ARG C 2 358 ? 30.976  37.131  55.106  1.00 40.34  ? 358  ARG A CZ    1 
ATOM   6126  N  NH1   . ARG C 2 358 ? 31.572  37.491  53.976  1.00 37.10  ? 358  ARG A NH1   1 
ATOM   6127  N  NH2   . ARG C 2 358 ? 30.025  36.212  55.078  1.00 34.47  ? 358  ARG A NH2   1 
ATOM   6128  N  N     . PHE C 2 359 ? 33.550  44.667  55.591  1.00 20.63  ? 359  PHE A N     1 
ATOM   6129  C  CA    . PHE C 2 359 ? 34.232  45.827  56.160  1.00 22.45  ? 359  PHE A CA    1 
ATOM   6130  C  C     . PHE C 2 359 ? 33.790  47.077  55.440  1.00 24.98  ? 359  PHE A C     1 
ATOM   6131  O  O     . PHE C 2 359 ? 33.657  47.085  54.223  1.00 35.69  ? 359  PHE A O     1 
ATOM   6132  C  CB    . PHE C 2 359 ? 35.773  45.694  56.140  1.00 21.66  ? 359  PHE A CB    1 
ATOM   6133  C  CG    . PHE C 2 359 ? 36.376  45.437  54.767  1.00 23.56  ? 359  PHE A CG    1 
ATOM   6134  C  CD1   . PHE C 2 359 ? 36.994  46.461  54.052  1.00 29.03  ? 359  PHE A CD1   1 
ATOM   6135  C  CD2   . PHE C 2 359 ? 36.384  44.157  54.225  1.00 20.01  ? 359  PHE A CD2   1 
ATOM   6136  C  CE1   . PHE C 2 359 ? 37.625  46.214  52.807  1.00 23.92  ? 359  PHE A CE1   1 
ATOM   6137  C  CE2   . PHE C 2 359 ? 37.000  43.894  53.001  1.00 20.48  ? 359  PHE A CE2   1 
ATOM   6138  C  CZ    . PHE C 2 359 ? 37.626  44.931  52.290  1.00 30.51  ? 359  PHE A CZ    1 
ATOM   6139  N  N     . ASP C 2 360 ? 33.562  48.134  56.199  1.00 24.53  ? 360  ASP A N     1 
ATOM   6140  C  CA    . ASP C 2 360 ? 33.122  49.390  55.633  1.00 26.82  ? 360  ASP A CA    1 
ATOM   6141  C  C     . ASP C 2 360 ? 34.229  50.410  55.429  1.00 29.96  ? 360  ASP A C     1 
ATOM   6142  O  O     . ASP C 2 360 ? 34.006  51.426  54.746  1.00 32.83  ? 360  ASP A O     1 
ATOM   6143  C  CB    . ASP C 2 360 ? 31.990  49.975  56.491  1.00 22.05  ? 360  ASP A CB    1 
ATOM   6144  C  CG    . ASP C 2 360 ? 30.646  49.306  56.198  1.00 39.34  ? 360  ASP A CG    1 
ATOM   6145  O  OD1   . ASP C 2 360 ? 30.580  48.530  55.210  1.00 37.12  ? 360  ASP A OD1   1 
ATOM   6146  O  OD2   . ASP C 2 360 ? 29.659  49.553  56.935  1.00 41.88  ? 360  ASP A OD2   1 
ATOM   6147  N  N     . THR C 2 361 ? 35.396  50.147  56.027  1.00 19.50  ? 361  THR A N     1 
ATOM   6148  C  CA    . THR C 2 361 ? 36.573  50.999  55.892  1.00 25.53  ? 361  THR A CA    1 
ATOM   6149  C  C     . THR C 2 361 ? 37.822  50.110  55.690  1.00 31.85  ? 361  THR A C     1 
ATOM   6150  O  O     . THR C 2 361 ? 37.874  48.982  56.172  1.00 25.87  ? 361  THR A O     1 
ATOM   6151  C  CB    . THR C 2 361 ? 36.793  51.860  57.132  1.00 30.11  ? 361  THR A CB    1 
ATOM   6152  O  OG1   . THR C 2 361 ? 37.103  51.029  58.254  1.00 33.30  ? 361  THR A OG1   1 
ATOM   6153  C  CG2   . THR C 2 361 ? 35.566  52.657  57.424  1.00 36.04  ? 361  THR A CG2   1 
ATOM   6154  N  N     . LEU C 2 362 ? 38.836  50.606  54.990  1.00 31.71  ? 362  LEU A N     1 
ATOM   6155  C  CA    . LEU C 2 362 ? 40.012  49.762  54.753  1.00 27.39  ? 362  LEU A CA    1 
ATOM   6156  C  C     . LEU C 2 362 ? 40.702  49.366  56.042  1.00 26.82  ? 362  LEU A C     1 
ATOM   6157  O  O     . LEU C 2 362 ? 41.303  48.291  56.132  1.00 25.95  ? 362  LEU A O     1 
ATOM   6158  C  CB    . LEU C 2 362 ? 41.012  50.464  53.839  1.00 20.04  ? 362  LEU A CB    1 
ATOM   6159  C  CG    . LEU C 2 362 ? 40.374  51.066  52.591  1.00 21.67  ? 362  LEU A CG    1 
ATOM   6160  C  CD1   . LEU C 2 362 ? 41.445  51.809  51.803  1.00 27.59  ? 362  LEU A CD1   1 
ATOM   6161  C  CD2   . LEU C 2 362 ? 39.726  49.990  51.745  1.00 26.28  ? 362  LEU A CD2   1 
ATOM   6162  N  N     . LYS C 2 363 ? 40.601  50.237  57.040  1.00 32.04  ? 363  LYS A N     1 
ATOM   6163  C  CA    . LYS C 2 363 ? 41.199  50.004  58.348  1.00 36.34  ? 363  LYS A CA    1 
ATOM   6164  C  C     . LYS C 2 363 ? 40.532  48.794  59.036  1.00 37.44  ? 363  LYS A C     1 
ATOM   6165  O  O     . LYS C 2 363 ? 41.197  48.026  59.740  1.00 36.16  ? 363  LYS A O     1 
ATOM   6166  C  CB    . LYS C 2 363 ? 41.059  51.282  59.191  1.00 41.67  ? 363  LYS A CB    1 
ATOM   6167  C  CG    . LYS C 2 363 ? 41.905  51.338  60.453  1.00 39.81  ? 363  LYS A CG    1 
ATOM   6168  C  CD    . LYS C 2 363 ? 41.870  52.762  61.030  1.00 56.65  ? 363  LYS A CD    1 
ATOM   6169  C  CE    . LYS C 2 363 ? 42.780  52.939  62.235  1.00 50.53  ? 363  LYS A CE    1 
ATOM   6170  N  NZ    . LYS C 2 363 ? 42.279  52.203  63.426  1.00 56.97  ? 363  LYS A NZ    1 
ATOM   6171  N  N     . GLU C 2 364 ? 39.227  48.617  58.810  1.00 34.01  ? 364  GLU A N     1 
ATOM   6172  C  CA    . GLU C 2 364 ? 38.502  47.491  59.380  1.00 31.50  ? 364  GLU A CA    1 
ATOM   6173  C  C     . GLU C 2 364 ? 38.974  46.136  58.857  1.00 36.80  ? 364  GLU A C     1 
ATOM   6174  O  O     . GLU C 2 364 ? 38.871  45.146  59.577  1.00 34.89  ? 364  GLU A O     1 
ATOM   6175  C  CB    . GLU C 2 364 ? 37.008  47.607  59.096  1.00 38.42  ? 364  GLU A CB    1 
ATOM   6176  C  CG    . GLU C 2 364 ? 36.203  48.204  60.221  1.00 36.96  ? 364  GLU A CG    1 
ATOM   6177  C  CD    . GLU C 2 364 ? 34.792  48.591  59.808  1.00 40.67  ? 364  GLU A CD    1 
ATOM   6178  O  OE1   . GLU C 2 364 ? 34.145  47.873  59.006  1.00 37.93  ? 364  GLU A OE1   1 
ATOM   6179  O  OE2   . GLU C 2 364 ? 34.318  49.622  60.311  1.00 48.91  ? 364  GLU A OE2   1 
ATOM   6180  N  N     . PHE C 2 365 ? 39.484  46.078  57.624  1.00 25.37  ? 365  PHE A N     1 
ATOM   6181  C  CA    . PHE C 2 365 ? 39.918  44.791  57.065  1.00 31.55  ? 365  PHE A CA    1 
ATOM   6182  C  C     . PHE C 2 365 ? 40.961  44.009  57.927  1.00 34.98  ? 365  PHE A C     1 
ATOM   6183  O  O     . PHE C 2 365 ? 40.747  42.843  58.256  1.00 37.04  ? 365  PHE A O     1 
ATOM   6184  C  CB    . PHE C 2 365 ? 40.439  44.982  55.633  1.00 32.40  ? 365  PHE A CB    1 
ATOM   6185  C  CG    . PHE C 2 365 ? 40.968  43.714  54.996  1.00 24.74  ? 365  PHE A CG    1 
ATOM   6186  C  CD1   . PHE C 2 365 ? 40.130  42.640  54.743  1.00 29.11  ? 365  PHE A CD1   1 
ATOM   6187  C  CD2   . PHE C 2 365 ? 42.298  43.620  54.614  1.00 25.19  ? 365  PHE A CD2   1 
ATOM   6188  C  CE1   . PHE C 2 365 ? 40.601  41.492  54.115  1.00 19.14  ? 365  PHE A CE1   1 
ATOM   6189  C  CE2   . PHE C 2 365 ? 42.788  42.485  53.988  1.00 24.21  ? 365  PHE A CE2   1 
ATOM   6190  C  CZ    . PHE C 2 365 ? 41.931  41.415  53.737  1.00 31.14  ? 365  PHE A CZ    1 
ATOM   6191  N  N     . PRO C 2 366 ? 42.097  44.629  58.287  1.00 34.41  ? 366  PRO A N     1 
ATOM   6192  C  CA    . PRO C 2 366 ? 43.099  43.928  59.107  1.00 33.78  ? 366  PRO A CA    1 
ATOM   6193  C  C     . PRO C 2 366 ? 42.518  43.522  60.462  1.00 34.74  ? 366  PRO A C     1 
ATOM   6194  O  O     . PRO C 2 366 ? 42.861  42.483  61.020  1.00 41.31  ? 366  PRO A O     1 
ATOM   6195  C  CB    . PRO C 2 366 ? 44.186  44.969  59.292  1.00 33.20  ? 366  PRO A CB    1 
ATOM   6196  C  CG    . PRO C 2 366 ? 44.066  45.801  58.046  1.00 36.97  ? 366  PRO A CG    1 
ATOM   6197  C  CD    . PRO C 2 366 ? 42.586  45.959  57.895  1.00 34.10  ? 366  PRO A CD    1 
ATOM   6198  N  N     . GLU C 2 367 ? 41.642  44.357  60.993  1.00 28.90  ? 367  GLU A N     1 
ATOM   6199  C  CA    . GLU C 2 367 ? 41.008  44.096  62.279  1.00 39.00  ? 367  GLU A CA    1 
ATOM   6200  C  C     . GLU C 2 367 ? 40.167  42.825  62.265  1.00 40.03  ? 367  GLU A C     1 
ATOM   6201  O  O     . GLU C 2 367 ? 40.421  41.902  63.020  1.00 50.49  ? 367  GLU A O     1 
ATOM   6202  C  CB    . GLU C 2 367 ? 40.093  45.263  62.666  1.00 41.76  ? 367  GLU A CB    1 
ATOM   6203  C  CG    . GLU C 2 367 ? 40.739  46.372  63.464  1.00 55.02  ? 367  GLU A CG    1 
ATOM   6204  C  CD    . GLU C 2 367 ? 39.889  47.649  63.499  1.00 66.77  ? 367  GLU A CD    1 
ATOM   6205  O  OE1   . GLU C 2 367 ? 38.639  47.536  63.566  1.00 64.47  ? 367  GLU A OE1   1 
ATOM   6206  O  OE2   . GLU C 2 367 ? 40.478  48.763  63.472  1.00 62.81  ? 367  GLU A OE2   1 
ATOM   6207  N  N     . LYS C 2 368 ? 39.170  42.787  61.390  1.00 35.49  ? 368  LYS A N     1 
ATOM   6208  C  CA    . LYS C 2 368 ? 38.256  41.666  61.293  1.00 34.68  ? 368  LYS A CA    1 
ATOM   6209  C  C     . LYS C 2 368 ? 38.807  40.386  60.649  1.00 40.78  ? 368  LYS A C     1 
ATOM   6210  O  O     . LYS C 2 368 ? 38.250  39.299  60.850  1.00 38.39  ? 368  LYS A O     1 
ATOM   6211  C  CB    . LYS C 2 368 ? 36.971  42.121  60.568  1.00 23.97  ? 368  LYS A CB    1 
ATOM   6212  C  CG    . LYS C 2 368 ? 36.336  43.353  61.180  1.00 37.25  ? 368  LYS A CG    1 
ATOM   6213  C  CD    . LYS C 2 368 ? 35.063  43.843  60.477  1.00 39.56  ? 368  LYS A CD    1 
ATOM   6214  C  CE    . LYS C 2 368 ? 33.843  42.998  60.885  1.00 60.65  ? 368  LYS A CE    1 
ATOM   6215  N  NZ    . LYS C 2 368 ? 32.523  43.585  60.451  1.00 59.10  ? 368  LYS A NZ    1 
ATOM   6216  N  N     . ALA C 2 369 ? 39.890  40.492  59.881  1.00 41.85  ? 369  ALA A N     1 
ATOM   6217  C  CA    . ALA C 2 369 ? 40.455  39.307  59.237  1.00 31.91  ? 369  ALA A CA    1 
ATOM   6218  C  C     . ALA C 2 369 ? 41.911  39.064  59.637  1.00 34.25  ? 369  ALA A C     1 
ATOM   6219  O  O     . ALA C 2 369 ? 42.686  38.483  58.870  1.00 40.95  ? 369  ALA A O     1 
ATOM   6220  C  CB    . ALA C 2 369 ? 40.353  39.435  57.724  1.00 34.95  ? 369  ALA A CB    1 
ATOM   6221  N  N     . ARG C 2 370 ? 42.294  39.503  60.830  1.00 29.75  ? 370  ARG A N     1 
ATOM   6222  C  CA    . ARG C 2 370 ? 43.672  39.306  61.294  1.00 32.01  ? 370  ARG A CA    1 
ATOM   6223  C  C     . ARG C 2 370 ? 44.087  37.820  61.275  1.00 32.81  ? 370  ARG A C     1 
ATOM   6224  O  O     . ARG C 2 370 ? 45.225  37.475  60.952  1.00 34.48  ? 370  ARG A O     1 
ATOM   6225  C  CB    . ARG C 2 370 ? 43.835  39.860  62.710  1.00 27.49  ? 370  ARG A CB    1 
ATOM   6226  C  CG    . ARG C 2 370 ? 45.283  39.945  63.209  1.00 44.52  ? 370  ARG A CG    1 
ATOM   6227  C  CD    . ARG C 2 370 ? 45.330  40.586  64.592  1.00 50.70  ? 370  ARG A CD    1 
ATOM   6228  N  NE    . ARG C 2 370 ? 46.652  40.516  65.191  1.00 56.71  ? 370  ARG A NE    1 
ATOM   6229  C  CZ    . ARG C 2 370 ? 47.677  41.288  64.842  1.00 61.58  ? 370  ARG A CZ    1 
ATOM   6230  N  NH1   . ARG C 2 370 ? 47.535  42.198  63.889  1.00 59.09  ? 370  ARG A NH1   1 
ATOM   6231  N  NH2   . ARG C 2 370 ? 48.850  41.152  65.454  1.00 62.24  ? 370  ARG A NH2   1 
ATOM   6232  N  N     . TYR C 2 371 ? 43.155  36.943  61.616  1.00 33.22  ? 371  TYR A N     1 
ATOM   6233  C  CA    . TYR C 2 371 ? 43.426  35.531  61.640  1.00 33.57  ? 371  TYR A CA    1 
ATOM   6234  C  C     . TYR C 2 371 ? 43.816  34.981  60.265  1.00 37.72  ? 371  TYR A C     1 
ATOM   6235  O  O     . TYR C 2 371 ? 44.437  33.933  60.186  1.00 36.30  ? 371  TYR A O     1 
ATOM   6236  C  CB    . TYR C 2 371 ? 42.212  34.787  62.188  1.00 35.27  ? 371  TYR A CB    1 
ATOM   6237  C  CG    . TYR C 2 371 ? 40.961  35.035  61.399  1.00 31.25  ? 371  TYR A CG    1 
ATOM   6238  C  CD1   . TYR C 2 371 ? 40.068  36.032  61.768  1.00 30.18  ? 371  TYR A CD1   1 
ATOM   6239  C  CD2   . TYR C 2 371 ? 40.662  34.261  60.284  1.00 35.64  ? 371  TYR A CD2   1 
ATOM   6240  C  CE1   . TYR C 2 371 ? 38.903  36.246  61.047  1.00 33.57  ? 371  TYR A CE1   1 
ATOM   6241  C  CE2   . TYR C 2 371 ? 39.505  34.465  59.557  1.00 28.13  ? 371  TYR A CE2   1 
ATOM   6242  C  CZ    . TYR C 2 371 ? 38.634  35.446  59.937  1.00 30.99  ? 371  TYR A CZ    1 
ATOM   6243  O  OH    . TYR C 2 371 ? 37.480  35.632  59.213  1.00 38.18  ? 371  TYR A OH    1 
ATOM   6244  N  N     . LEU C 2 372 ? 43.461  35.684  59.191  1.00 40.28  ? 372  LEU A N     1 
ATOM   6245  C  CA    . LEU C 2 372 ? 43.796  35.236  57.841  1.00 35.86  ? 372  LEU A CA    1 
ATOM   6246  C  C     . LEU C 2 372 ? 45.243  35.521  57.448  1.00 37.97  ? 372  LEU A C     1 
ATOM   6247  O  O     . LEU C 2 372 ? 45.726  35.018  56.436  1.00 37.03  ? 372  LEU A O     1 
ATOM   6248  C  CB    . LEU C 2 372 ? 42.887  35.906  56.818  1.00 36.16  ? 372  LEU A CB    1 
ATOM   6249  C  CG    . LEU C 2 372 ? 41.417  35.503  56.820  1.00 34.49  ? 372  LEU A CG    1 
ATOM   6250  C  CD1   . LEU C 2 372 ? 40.726  36.187  55.664  1.00 33.39  ? 372  LEU A CD1   1 
ATOM   6251  C  CD2   . LEU C 2 372 ? 41.288  33.993  56.692  1.00 29.87  ? 372  LEU A CD2   1 
ATOM   6252  N  N     . PHE C 2 373 ? 45.941  36.310  58.250  1.00 35.87  ? 373  PHE A N     1 
ATOM   6253  C  CA    . PHE C 2 373 ? 47.317  36.685  57.929  1.00 39.42  ? 373  PHE A CA    1 
ATOM   6254  C  C     . PHE C 2 373 ? 48.364  36.371  59.011  1.00 43.73  ? 373  PHE A C     1 
ATOM   6255  O  O     . PHE C 2 373 ? 49.562  36.429  58.745  1.00 39.81  ? 373  PHE A O     1 
ATOM   6256  C  CB    . PHE C 2 373 ? 47.380  38.188  57.622  1.00 34.70  ? 373  PHE A CB    1 
ATOM   6257  C  CG    . PHE C 2 373 ? 46.502  38.617  56.491  1.00 32.00  ? 373  PHE A CG    1 
ATOM   6258  C  CD1   . PHE C 2 373 ? 46.930  38.502  55.174  1.00 33.03  ? 373  PHE A CD1   1 
ATOM   6259  C  CD2   . PHE C 2 373 ? 45.240  39.129  56.738  1.00 33.33  ? 373  PHE A CD2   1 
ATOM   6260  C  CE1   . PHE C 2 373 ? 46.120  38.888  54.130  1.00 24.62  ? 373  PHE A CE1   1 
ATOM   6261  C  CE2   . PHE C 2 373 ? 44.429  39.512  55.695  1.00 34.64  ? 373  PHE A CE2   1 
ATOM   6262  C  CZ    . PHE C 2 373 ? 44.874  39.390  54.388  1.00 27.47  ? 373  PHE A CZ    1 
ATOM   6263  N  N     . THR C 2 374 ? 47.925  36.077  60.230  1.00 46.31  ? 374  THR A N     1 
ATOM   6264  C  CA    . THR C 2 374 ? 48.866  35.765  61.290  1.00 39.22  ? 374  THR A CA    1 
ATOM   6265  C  C     . THR C 2 374 ? 48.269  34.769  62.267  1.00 50.64  ? 374  THR A C     1 
ATOM   6266  O  O     . THR C 2 374 ? 47.041  34.593  62.342  1.00 45.39  ? 374  THR A O     1 
ATOM   6267  C  CB    . THR C 2 374 ? 49.275  37.038  62.057  1.00 47.66  ? 374  THR A CB    1 
ATOM   6268  O  OG1   . THR C 2 374 ? 50.369  36.746  62.928  1.00 45.77  ? 374  THR A OG1   1 
ATOM   6269  C  CG2   . THR C 2 374 ? 48.112  37.571  62.891  1.00 47.10  ? 374  THR A CG2   1 
ATOM   6270  N  N     . GLU C 2 375 ? 49.151  34.112  63.015  1.00 52.85  ? 375  GLU A N     1 
ATOM   6271  C  CA    . GLU C 2 375 ? 48.732  33.147  64.023  1.00 51.90  ? 375  GLU A CA    1 
ATOM   6272  C  C     . GLU C 2 375 ? 48.473  33.926  65.330  1.00 52.27  ? 375  GLU A C     1 
ATOM   6273  O  O     . GLU C 2 375 ? 47.776  33.461  66.249  1.00 51.31  ? 375  GLU A O     1 
ATOM   6274  C  CB    . GLU C 2 375 ? 49.821  32.091  64.210  1.00 50.82  ? 375  GLU A CB    1 
ATOM   6275  C  CG    . GLU C 2 375 ? 49.277  30.676  64.284  1.00 64.94  ? 375  GLU A CG    1 
ATOM   6276  C  CD    . GLU C 2 375 ? 48.712  30.172  62.960  1.00 70.94  ? 375  GLU A CD    1 
ATOM   6277  O  OE1   . GLU C 2 375 ? 47.837  29.267  62.990  1.00 68.86  ? 375  GLU A OE1   1 
ATOM   6278  O  OE2   . GLU C 2 375 ? 49.151  30.667  61.895  1.00 70.41  ? 375  GLU A OE2   1 
ATOM   6279  N  N     . ASP C 2 376 ? 49.033  35.127  65.383  1.00 42.86  ? 376  ASP A N     1 
ATOM   6280  C  CA    . ASP C 2 376 ? 48.871  36.012  66.528  1.00 53.06  ? 376  ASP A CA    1 
ATOM   6281  C  C     . ASP C 2 376 ? 47.462  36.666  66.524  1.00 48.20  ? 376  ASP A C     1 
ATOM   6282  O  O     . ASP C 2 376 ? 47.338  37.890  66.420  1.00 59.00  ? 376  ASP A O     1 
ATOM   6283  C  CB    . ASP C 2 376 ? 49.945  37.100  66.455  1.00 51.48  ? 376  ASP A CB    1 
ATOM   6284  C  CG    . ASP C 2 376 ? 49.914  38.034  67.642  1.00 66.53  ? 376  ASP A CG    1 
ATOM   6285  O  OD1   . ASP C 2 376 ? 50.261  39.229  67.452  1.00 66.09  ? 376  ASP A OD1   1 
ATOM   6286  O  OD2   . ASP C 2 376 ? 49.557  37.568  68.756  1.00 64.01  ? 376  ASP A OD2   1 
ATOM   6287  N  N     . TYR C 2 377 ? 46.406  35.866  66.610  1.00 47.13  ? 377  TYR A N     1 
ATOM   6288  C  CA    . TYR C 2 377 ? 45.052  36.419  66.612  1.00 47.41  ? 377  TYR A CA    1 
ATOM   6289  C  C     . TYR C 2 377 ? 44.345  36.168  67.932  1.00 48.78  ? 377  TYR A C     1 
ATOM   6290  O  O     . TYR C 2 377 ? 44.729  35.283  68.692  1.00 55.11  ? 377  TYR A O     1 
ATOM   6291  C  CB    . TYR C 2 377 ? 44.214  35.835  65.474  1.00 44.86  ? 377  TYR A CB    1 
ATOM   6292  C  CG    . TYR C 2 377 ? 44.064  34.332  65.504  1.00 52.95  ? 377  TYR A CG    1 
ATOM   6293  C  CD1   . TYR C 2 377 ? 45.075  33.496  65.010  1.00 47.21  ? 377  TYR A CD1   1 
ATOM   6294  C  CD2   . TYR C 2 377 ? 42.912  33.743  66.011  1.00 45.06  ? 377  TYR A CD2   1 
ATOM   6295  C  CE1   . TYR C 2 377 ? 44.935  32.116  65.017  1.00 51.13  ? 377  TYR A CE1   1 
ATOM   6296  C  CE2   . TYR C 2 377 ? 42.763  32.359  66.029  1.00 52.10  ? 377  TYR A CE2   1 
ATOM   6297  C  CZ    . TYR C 2 377 ? 43.773  31.547  65.532  1.00 56.34  ? 377  TYR A CZ    1 
ATOM   6298  O  OH    . TYR C 2 377 ? 43.620  30.167  65.559  1.00 58.74  ? 377  TYR A OH    1 
ATOM   6299  N  N     . PRO C 2 378 ? 43.294  36.940  68.220  1.00 43.66  ? 378  PRO A N     1 
ATOM   6300  C  CA    . PRO C 2 378 ? 42.538  36.793  69.463  1.00 47.04  ? 378  PRO A CA    1 
ATOM   6301  C  C     . PRO C 2 378 ? 41.405  35.768  69.392  1.00 51.62  ? 378  PRO A C     1 
ATOM   6302  O  O     . PRO C 2 378 ? 40.735  35.637  68.362  1.00 52.41  ? 378  PRO A O     1 
ATOM   6303  C  CB    . PRO C 2 378 ? 41.980  38.186  69.668  1.00 48.44  ? 378  PRO A CB    1 
ATOM   6304  C  CG    . PRO C 2 378 ? 41.548  38.531  68.249  1.00 41.90  ? 378  PRO A CG    1 
ATOM   6305  C  CD    . PRO C 2 378 ? 42.784  38.084  67.439  1.00 48.53  ? 378  PRO A CD    1 
ATOM   6306  N  N     . VAL C 2 379 ? 41.183  35.049  70.490  1.00 47.60  ? 379  VAL A N     1 
ATOM   6307  C  CA    . VAL C 2 379 ? 40.086  34.093  70.542  1.00 42.25  ? 379  VAL A CA    1 
ATOM   6308  C  C     . VAL C 2 379 ? 39.060  34.633  71.535  1.00 48.01  ? 379  VAL A C     1 
ATOM   6309  O  O     . VAL C 2 379 ? 39.364  34.799  72.721  1.00 50.25  ? 379  VAL A O     1 
ATOM   6310  C  CB    . VAL C 2 379 ? 40.554  32.701  70.998  1.00 42.23  ? 379  VAL A CB    1 
ATOM   6311  C  CG1   . VAL C 2 379 ? 39.358  31.724  71.024  1.00 33.54  ? 379  VAL A CG1   1 
ATOM   6312  C  CG2   . VAL C 2 379 ? 41.650  32.202  70.058  1.00 40.08  ? 379  VAL A CG2   1 
ATOM   6313  N  N     . SER C 2 380 ? 37.854  34.927  71.055  1.00 43.80  ? 380  SER A N     1 
ATOM   6314  C  CA    . SER C 2 380 ? 36.818  35.461  71.935  1.00 45.99  ? 380  SER A CA    1 
ATOM   6315  C  C     . SER C 2 380 ? 36.298  34.407  72.894  1.00 51.43  ? 380  SER A C     1 
ATOM   6316  O  O     . SER C 2 380 ? 36.365  33.211  72.609  1.00 53.10  ? 380  SER A O     1 
ATOM   6317  C  CB    . SER C 2 380 ? 35.634  35.969  71.123  1.00 50.65  ? 380  SER A CB    1 
ATOM   6318  O  OG    . SER C 2 380 ? 34.810  34.899  70.701  1.00 42.60  ? 380  SER A OG    1 
ATOM   6319  N  N     . GLU C 2 381 ? 35.742  34.863  74.015  1.00 61.66  ? 381  GLU A N     1 
ATOM   6320  C  CA    . GLU C 2 381 ? 35.180  33.960  75.021  1.00 59.33  ? 381  GLU A CA    1 
ATOM   6321  C  C     . GLU C 2 381 ? 34.100  33.068  74.407  1.00 54.32  ? 381  GLU A C     1 
ATOM   6322  O  O     . GLU C 2 381 ? 34.129  31.854  74.613  1.00 51.64  ? 381  GLU A O     1 
ATOM   6323  C  CB    . GLU C 2 381 ? 34.602  34.745  76.214  1.00 60.24  ? 381  GLU A CB    1 
ATOM   6324  C  CG    . GLU C 2 381 ? 34.373  33.866  77.459  1.00 71.47  ? 381  GLU A CG    1 
ATOM   6325  C  CD    . GLU C 2 381 ? 34.122  34.661  78.739  1.00 83.28  ? 381  GLU A CD    1 
ATOM   6326  O  OE1   . GLU C 2 381 ? 35.017  35.443  79.142  1.00 87.39  ? 381  GLU A OE1   1 
ATOM   6327  O  OE2   . GLU C 2 381 ? 33.036  34.496  79.348  1.00 80.72  ? 381  GLU A OE2   1 
ATOM   6328  N  N     . LYS C 2 382 ? 33.167  33.659  73.656  1.00 45.36  ? 382  LYS A N     1 
ATOM   6329  C  CA    . LYS C 2 382 ? 32.100  32.894  73.004  1.00 51.92  ? 382  LYS A CA    1 
ATOM   6330  C  C     . LYS C 2 382 ? 32.650  31.851  72.020  1.00 50.15  ? 382  LYS A C     1 
ATOM   6331  O  O     . LYS C 2 382 ? 32.059  30.785  71.826  1.00 54.09  ? 382  LYS A O     1 
ATOM   6332  C  CB    . LYS C 2 382 ? 31.141  33.817  72.243  1.00 54.64  ? 382  LYS A CB    1 
ATOM   6333  C  CG    . LYS C 2 382 ? 30.074  34.489  73.085  1.00 65.48  ? 382  LYS A CG    1 
ATOM   6334  C  CD    . LYS C 2 382 ? 29.234  35.448  72.234  1.00 69.56  ? 382  LYS A CD    1 
ATOM   6335  C  CE    . LYS C 2 382 ? 28.437  34.707  71.143  1.00 81.37  ? 382  LYS A CE    1 
ATOM   6336  N  NZ    . LYS C 2 382 ? 27.272  33.899  71.653  1.00 75.51  ? 382  LYS A NZ    1 
ATOM   6337  N  N     . ALA C 2 383 ? 33.770  32.168  71.385  1.00 49.04  ? 383  ALA A N     1 
ATOM   6338  C  CA    . ALA C 2 383 ? 34.385  31.254  70.436  1.00 43.48  ? 383  ALA A CA    1 
ATOM   6339  C  C     . ALA C 2 383 ? 35.072  30.132  71.202  1.00 37.12  ? 383  ALA A C     1 
ATOM   6340  O  O     . ALA C 2 383 ? 34.996  28.965  70.814  1.00 30.15  ? 383  ALA A O     1 
ATOM   6341  C  CB    . ALA C 2 383 ? 35.403  32.002  69.565  1.00 47.51  ? 383  ALA A CB    1 
ATOM   6342  N  N     . GLN C 2 384 ? 35.727  30.494  72.302  1.00 38.43  ? 384  GLN A N     1 
ATOM   6343  C  CA    . GLN C 2 384 ? 36.435  29.515  73.124  1.00 46.21  ? 384  GLN A CA    1 
ATOM   6344  C  C     . GLN C 2 384 ? 35.435  28.549  73.737  1.00 44.97  ? 384  GLN A C     1 
ATOM   6345  O  O     . GLN C 2 384 ? 35.696  27.362  73.897  1.00 52.40  ? 384  GLN A O     1 
ATOM   6346  C  CB    . GLN C 2 384 ? 37.223  30.212  74.234  1.00 43.26  ? 384  GLN A CB    1 
ATOM   6347  C  CG    . GLN C 2 384 ? 38.193  29.305  74.946  1.00 54.18  ? 384  GLN A CG    1 
ATOM   6348  C  CD    . GLN C 2 384 ? 39.158  28.599  73.986  1.00 68.57  ? 384  GLN A CD    1 
ATOM   6349  O  OE1   . GLN C 2 384 ? 39.976  29.236  73.308  1.00 70.69  ? 384  GLN A OE1   1 
ATOM   6350  N  NE2   . GLN C 2 384 ? 39.058  27.275  73.925  1.00 69.89  ? 384  GLN A NE2   1 
ATOM   6351  N  N     . ARG C 2 385 ? 34.270  29.066  74.060  1.00 43.31  ? 385  ARG A N     1 
ATOM   6352  C  CA    . ARG C 2 385 ? 33.243  28.248  74.660  1.00 50.82  ? 385  ARG A CA    1 
ATOM   6353  C  C     . ARG C 2 385 ? 32.688  27.286  73.607  1.00 49.55  ? 385  ARG A C     1 
ATOM   6354  O  O     . ARG C 2 385 ? 32.495  26.110  73.899  1.00 51.02  ? 385  ARG A O     1 
ATOM   6355  C  CB    . ARG C 2 385 ? 32.151  29.165  75.232  1.00 52.44  ? 385  ARG A CB    1 
ATOM   6356  C  CG    . ARG C 2 385 ? 31.265  28.541  76.288  1.00 60.14  ? 385  ARG A CG    1 
ATOM   6357  C  CD    . ARG C 2 385 ? 30.588  29.625  77.130  1.00 58.08  ? 385  ARG A CD    1 
ATOM   6358  N  NE    . ARG C 2 385 ? 29.759  30.519  76.323  1.00 57.33  ? 385  ARG A NE    1 
ATOM   6359  C  CZ    . ARG C 2 385 ? 29.800  31.851  76.384  1.00 60.05  ? 385  ARG A CZ    1 
ATOM   6360  N  NH1   . ARG C 2 385 ? 30.640  32.461  77.221  1.00 55.00  ? 385  ARG A NH1   1 
ATOM   6361  N  NH2   . ARG C 2 385 ? 28.999  32.579  75.605  1.00 49.28  ? 385  ARG A NH2   1 
ATOM   6362  N  N     . LYS C 2 386 ? 32.450  27.785  72.388  1.00 49.60  ? 386  LYS A N     1 
ATOM   6363  C  CA    . LYS C 2 386 ? 31.913  26.966  71.290  1.00 45.21  ? 386  LYS A CA    1 
ATOM   6364  C  C     . LYS C 2 386 ? 32.933  25.893  70.928  1.00 46.54  ? 386  LYS A C     1 
ATOM   6365  O  O     . LYS C 2 386 ? 32.580  24.758  70.581  1.00 36.00  ? 386  LYS A O     1 
ATOM   6366  C  CB    . LYS C 2 386 ? 31.650  27.814  70.047  1.00 45.69  ? 386  LYS A CB    1 
ATOM   6367  C  CG    . LYS C 2 386 ? 30.440  27.387  69.242  1.00 44.14  ? 386  LYS A CG    1 
ATOM   6368  C  CD    . LYS C 2 386 ? 29.165  27.727  70.036  1.00 58.77  ? 386  LYS A CD    1 
ATOM   6369  C  CE    . LYS C 2 386 ? 27.919  27.865  69.168  1.00 50.00  ? 386  LYS A CE    1 
ATOM   6370  N  NZ    . LYS C 2 386 ? 27.446  26.559  68.625  1.00 72.19  ? 386  LYS A NZ    1 
ATOM   6371  N  N     . LEU C 2 387 ? 34.202  26.272  71.008  1.00 36.85  ? 387  LEU A N     1 
ATOM   6372  C  CA    . LEU C 2 387 ? 35.265  25.347  70.699  1.00 44.03  ? 387  LEU A CA    1 
ATOM   6373  C  C     . LEU C 2 387 ? 35.238  24.193  71.703  1.00 49.06  ? 387  LEU A C     1 
ATOM   6374  O  O     . LEU C 2 387 ? 35.203  23.027  71.307  1.00 50.88  ? 387  LEU A O     1 
ATOM   6375  C  CB    . LEU C 2 387 ? 36.625  26.066  70.719  1.00 31.61  ? 387  LEU A CB    1 
ATOM   6376  C  CG    . LEU C 2 387 ? 37.867  25.214  70.447  1.00 34.36  ? 387  LEU A CG    1 
ATOM   6377  C  CD1   . LEU C 2 387 ? 37.643  24.370  69.202  1.00 33.35  ? 387  LEU A CD1   1 
ATOM   6378  C  CD2   . LEU C 2 387 ? 39.089  26.116  70.291  1.00 23.58  ? 387  LEU A CD2   1 
ATOM   6379  N  N     . GLU C 2 388 ? 35.232  24.514  72.994  1.00 49.76  ? 388  GLU A N     1 
ATOM   6380  C  CA    . GLU C 2 388 ? 35.216  23.479  74.022  1.00 54.14  ? 388  GLU A CA    1 
ATOM   6381  C  C     . GLU C 2 388 ? 34.052  22.522  73.855  1.00 52.75  ? 388  GLU A C     1 
ATOM   6382  O  O     . GLU C 2 388 ? 34.220  21.307  73.904  1.00 53.74  ? 388  GLU A O     1 
ATOM   6383  C  CB    . GLU C 2 388 ? 35.128  24.101  75.406  1.00 55.89  ? 388  GLU A CB    1 
ATOM   6384  C  CG    . GLU C 2 388 ? 36.300  24.964  75.769  1.00 69.62  ? 388  GLU A CG    1 
ATOM   6385  C  CD    . GLU C 2 388 ? 36.114  25.606  77.127  1.00 88.27  ? 388  GLU A CD    1 
ATOM   6386  O  OE1   . GLU C 2 388 ? 35.012  26.156  77.378  1.00 93.32  ? 388  GLU A OE1   1 
ATOM   6387  O  OE2   . GLU C 2 388 ? 37.064  25.565  77.940  1.00 94.03  ? 388  GLU A OE2   1 
ATOM   6388  N  N     . GLU C 2 389 ? 32.866  23.073  73.654  1.00 49.58  ? 389  GLU A N     1 
ATOM   6389  C  CA    . GLU C 2 389 ? 31.683  22.247  73.512  1.00 53.80  ? 389  GLU A CA    1 
ATOM   6390  C  C     . GLU C 2 389 ? 31.738  21.294  72.332  1.00 48.45  ? 389  GLU A C     1 
ATOM   6391  O  O     . GLU C 2 389 ? 31.195  20.199  72.392  1.00 54.72  ? 389  GLU A O     1 
ATOM   6392  C  CB    . GLU C 2 389 ? 30.449  23.140  73.420  1.00 53.44  ? 389  GLU A CB    1 
ATOM   6393  C  CG    . GLU C 2 389 ? 30.229  23.929  74.697  1.00 59.19  ? 389  GLU A CG    1 
ATOM   6394  C  CD    . GLU C 2 389 ? 28.933  24.712  74.692  1.00 70.72  ? 389  GLU A CD    1 
ATOM   6395  O  OE1   . GLU C 2 389 ? 28.563  25.255  75.764  1.00 69.15  ? 389  GLU A OE1   1 
ATOM   6396  O  OE2   . GLU C 2 389 ? 28.290  24.780  73.618  1.00 69.84  ? 389  GLU A OE2   1 
ATOM   6397  N  N     . GLY C 2 390 ? 32.409  21.704  71.266  1.00 48.20  ? 390  GLY A N     1 
ATOM   6398  C  CA    . GLY C 2 390 ? 32.497  20.862  70.090  1.00 43.15  ? 390  GLY A CA    1 
ATOM   6399  C  C     . GLY C 2 390 ? 33.757  20.023  69.932  1.00 42.32  ? 390  GLY A C     1 
ATOM   6400  O  O     . GLY C 2 390 ? 33.900  19.330  68.936  1.00 39.42  ? 390  GLY A O     1 
ATOM   6401  N  N     . LEU C 2 391 ? 34.663  20.076  70.903  1.00 45.68  ? 391  LEU A N     1 
ATOM   6402  C  CA    . LEU C 2 391 ? 35.900  19.306  70.842  1.00 50.87  ? 391  LEU A CA    1 
ATOM   6403  C  C     . LEU C 2 391 ? 35.704  17.819  70.541  1.00 51.69  ? 391  LEU A C     1 
ATOM   6404  O  O     . LEU C 2 391 ? 36.438  17.237  69.742  1.00 54.95  ? 391  LEU A O     1 
ATOM   6405  C  CB    . LEU C 2 391 ? 36.680  19.463  72.149  1.00 49.24  ? 391  LEU A CB    1 
ATOM   6406  C  CG    . LEU C 2 391 ? 37.752  20.548  72.097  1.00 52.68  ? 391  LEU A CG    1 
ATOM   6407  C  CD1   . LEU C 2 391 ? 38.363  20.761  73.466  1.00 51.05  ? 391  LEU A CD1   1 
ATOM   6408  C  CD2   . LEU C 2 391 ? 38.812  20.138  71.107  1.00 51.58  ? 391  LEU A CD2   1 
ATOM   6409  N  N     . PRO C 2 392 ? 34.714  17.187  71.175  1.00 47.79  ? 392  PRO A N     1 
ATOM   6410  C  CA    . PRO C 2 392 ? 34.470  15.766  70.935  1.00 52.00  ? 392  PRO A CA    1 
ATOM   6411  C  C     . PRO C 2 392 ? 34.203  15.417  69.470  1.00 54.31  ? 392  PRO A C     1 
ATOM   6412  O  O     . PRO C 2 392 ? 34.814  14.483  68.940  1.00 54.84  ? 392  PRO A O     1 
ATOM   6413  C  CB    . PRO C 2 392 ? 33.275  15.470  71.843  1.00 58.04  ? 392  PRO A CB    1 
ATOM   6414  C  CG    . PRO C 2 392 ? 33.514  16.400  72.996  1.00 52.01  ? 392  PRO A CG    1 
ATOM   6415  C  CD    . PRO C 2 392 ? 33.872  17.678  72.277  1.00 51.75  ? 392  PRO A CD    1 
ATOM   6416  N  N     . LEU C 2 393 ? 33.296  16.140  68.811  1.00 53.12  ? 393  LEU A N     1 
ATOM   6417  C  CA    . LEU C 2 393 ? 33.025  15.831  67.411  1.00 51.62  ? 393  LEU A CA    1 
ATOM   6418  C  C     . LEU C 2 393 ? 34.129  16.358  66.499  1.00 51.18  ? 393  LEU A C     1 
ATOM   6419  O  O     . LEU C 2 393 ? 34.318  15.847  65.401  1.00 54.16  ? 393  LEU A O     1 
ATOM   6420  C  CB    . LEU C 2 393 ? 31.641  16.322  66.958  1.00 49.41  ? 393  LEU A CB    1 
ATOM   6421  C  CG    . LEU C 2 393 ? 31.157  17.729  67.248  1.00 56.45  ? 393  LEU A CG    1 
ATOM   6422  C  CD1   . LEU C 2 393 ? 29.818  17.936  66.577  1.00 57.10  ? 393  LEU A CD1   1 
ATOM   6423  C  CD2   . LEU C 2 393 ? 31.025  17.925  68.756  1.00 71.24  ? 393  LEU A CD2   1 
ATOM   6424  N  N     . LEU C 2 394 ? 34.876  17.359  66.945  1.00 47.83  ? 394  LEU A N     1 
ATOM   6425  C  CA    . LEU C 2 394 ? 35.971  17.837  66.119  1.00 52.00  ? 394  LEU A CA    1 
ATOM   6426  C  C     . LEU C 2 394 ? 37.040  16.758  66.098  1.00 51.74  ? 394  LEU A C     1 
ATOM   6427  O  O     . LEU C 2 394 ? 37.615  16.480  65.054  1.00 49.62  ? 394  LEU A O     1 
ATOM   6428  C  CB    . LEU C 2 394 ? 36.566  19.140  66.659  1.00 47.21  ? 394  LEU A CB    1 
ATOM   6429  C  CG    . LEU C 2 394 ? 35.736  20.373  66.283  1.00 61.95  ? 394  LEU A CG    1 
ATOM   6430  C  CD1   . LEU C 2 394 ? 36.441  21.640  66.738  1.00 54.77  ? 394  LEU A CD1   1 
ATOM   6431  C  CD2   . LEU C 2 394 ? 35.528  20.395  64.769  1.00 60.92  ? 394  LEU A CD2   1 
ATOM   6432  N  N     . LYS C 2 395 ? 37.309  16.149  67.253  1.00 55.31  ? 395  LYS A N     1 
ATOM   6433  C  CA    . LYS C 2 395 ? 38.323  15.093  67.322  1.00 54.82  ? 395  LYS A CA    1 
ATOM   6434  C  C     . LYS C 2 395 ? 37.901  13.932  66.420  1.00 53.93  ? 395  LYS A C     1 
ATOM   6435  O  O     . LYS C 2 395 ? 38.740  13.321  65.765  1.00 47.79  ? 395  LYS A O     1 
ATOM   6436  C  CB    . LYS C 2 395 ? 38.532  14.613  68.765  1.00 48.22  ? 395  LYS A CB    1 
ATOM   6437  C  CG    . LYS C 2 395 ? 38.934  15.733  69.727  1.00 58.19  ? 395  LYS A CG    1 
ATOM   6438  C  CD    . LYS C 2 395 ? 39.874  15.246  70.830  1.00 62.71  ? 395  LYS A CD    1 
ATOM   6439  C  CE    . LYS C 2 395 ? 40.053  16.272  71.963  1.00 57.21  ? 395  LYS A CE    1 
ATOM   6440  N  NZ    . LYS C 2 395 ? 38.939  16.185  72.977  1.00 56.88  ? 395  LYS A NZ    1 
ATOM   6441  N  N     . GLU C 2 396 ? 36.603  13.645  66.373  1.00 50.87  ? 396  GLU A N     1 
ATOM   6442  C  CA    . GLU C 2 396 ? 36.102  12.585  65.505  1.00 60.23  ? 396  GLU A CA    1 
ATOM   6443  C  C     . GLU C 2 396 ? 36.142  12.982  64.018  1.00 63.24  ? 396  GLU A C     1 
ATOM   6444  O  O     . GLU C 2 396 ? 36.183  12.112  63.140  1.00 64.29  ? 396  GLU A O     1 
ATOM   6445  C  CB    . GLU C 2 396 ? 34.661  12.200  65.879  1.00 67.22  ? 396  GLU A CB    1 
ATOM   6446  C  CG    . GLU C 2 396 ? 34.552  11.062  66.894  1.00 77.65  ? 396  GLU A CG    1 
ATOM   6447  C  CD    . GLU C 2 396 ? 33.207  10.343  66.828  1.00 84.81  ? 396  GLU A CD    1 
ATOM   6448  O  OE1   . GLU C 2 396 ? 32.821  9.899   65.718  1.00 83.76  ? 396  GLU A OE1   1 
ATOM   6449  O  OE2   . GLU C 2 396 ? 32.543  10.215  67.884  1.00 83.98  ? 396  GLU A OE2   1 
ATOM   6450  N  N     . LEU C 2 397 ? 36.121  14.284  63.734  1.00 57.81  ? 397  LEU A N     1 
ATOM   6451  C  CA    . LEU C 2 397 ? 36.156  14.750  62.356  1.00 53.39  ? 397  LEU A CA    1 
ATOM   6452  C  C     . LEU C 2 397 ? 37.597  14.832  61.842  1.00 56.42  ? 397  LEU A C     1 
ATOM   6453  O  O     . LEU C 2 397 ? 37.875  14.479  60.692  1.00 54.99  ? 397  LEU A O     1 
ATOM   6454  C  CB    . LEU C 2 397 ? 35.482  16.126  62.246  1.00 50.95  ? 397  LEU A CB    1 
ATOM   6455  C  CG    . LEU C 2 397 ? 35.469  16.840  60.884  1.00 51.34  ? 397  LEU A CG    1 
ATOM   6456  C  CD1   . LEU C 2 397 ? 34.587  16.107  59.912  1.00 45.60  ? 397  LEU A CD1   1 
ATOM   6457  C  CD2   . LEU C 2 397 ? 34.954  18.245  61.053  1.00 46.75  ? 397  LEU A CD2   1 
ATOM   6458  N  N     . TYR C 2 398 ? 38.511  15.272  62.701  1.00 48.20  ? 398  TYR A N     1 
ATOM   6459  C  CA    . TYR C 2 398 ? 39.901  15.432  62.303  1.00 53.96  ? 398  TYR A CA    1 
ATOM   6460  C  C     . TYR C 2 398 ? 40.436  14.339  61.387  1.00 63.94  ? 398  TYR A C     1 
ATOM   6461  O  O     . TYR C 2 398 ? 40.891  14.628  60.280  1.00 67.04  ? 398  TYR A O     1 
ATOM   6462  C  CB    . TYR C 2 398 ? 40.812  15.531  63.517  1.00 46.34  ? 398  TYR A CB    1 
ATOM   6463  C  CG    . TYR C 2 398 ? 42.256  15.696  63.120  1.00 52.84  ? 398  TYR A CG    1 
ATOM   6464  C  CD1   . TYR C 2 398 ? 42.828  16.959  63.003  1.00 55.90  ? 398  TYR A CD1   1 
ATOM   6465  C  CD2   . TYR C 2 398 ? 43.047  14.590  62.826  1.00 53.58  ? 398  TYR A CD2   1 
ATOM   6466  C  CE1   . TYR C 2 398 ? 44.155  17.119  62.604  1.00 57.41  ? 398  TYR A CE1   1 
ATOM   6467  C  CE2   . TYR C 2 398 ? 44.375  14.737  62.426  1.00 54.23  ? 398  TYR A CE2   1 
ATOM   6468  C  CZ    . TYR C 2 398 ? 44.927  16.000  62.317  1.00 60.47  ? 398  TYR A CZ    1 
ATOM   6469  O  OH    . TYR C 2 398 ? 46.247  16.141  61.928  1.00 57.03  ? 398  TYR A OH    1 
ATOM   6470  N  N     . PRO C 2 399 ? 40.415  13.066  61.840  1.00 66.99  ? 399  PRO A N     1 
ATOM   6471  C  CA    . PRO C 2 399 ? 40.927  11.997  60.974  1.00 63.76  ? 399  PRO A CA    1 
ATOM   6472  C  C     . PRO C 2 399 ? 40.303  11.965  59.570  1.00 64.15  ? 399  PRO A C     1 
ATOM   6473  O  O     . PRO C 2 399 ? 41.016  11.780  58.582  1.00 64.31  ? 399  PRO A O     1 
ATOM   6474  C  CB    . PRO C 2 399 ? 40.655  10.730  61.794  1.00 62.30  ? 399  PRO A CB    1 
ATOM   6475  C  CG    . PRO C 2 399 ? 39.503  11.135  62.712  1.00 59.84  ? 399  PRO A CG    1 
ATOM   6476  C  CD    . PRO C 2 399 ? 39.911  12.516  63.112  1.00 56.62  ? 399  PRO A CD    1 
ATOM   6477  N  N     . ARG C 2 400 ? 38.986  12.160  59.481  1.00 64.63  ? 400  ARG A N     1 
ATOM   6478  C  CA    . ARG C 2 400 ? 38.298  12.152  58.191  1.00 64.82  ? 400  ARG A CA    1 
ATOM   6479  C  C     . ARG C 2 400 ? 38.814  13.305  57.335  1.00 71.03  ? 400  ARG A C     1 
ATOM   6480  O  O     . ARG C 2 400 ? 38.741  13.267  56.103  1.00 76.02  ? 400  ARG A O     1 
ATOM   6481  C  CB    . ARG C 2 400 ? 36.789  12.331  58.369  1.00 66.56  ? 400  ARG A CB    1 
ATOM   6482  C  CG    . ARG C 2 400 ? 36.130  11.428  59.398  1.00 68.50  ? 400  ARG A CG    1 
ATOM   6483  C  CD    . ARG C 2 400 ? 35.559  10.175  58.778  1.00 64.57  ? 400  ARG A CD    1 
ATOM   6484  N  NE    . ARG C 2 400 ? 34.550  9.562   59.639  1.00 69.82  ? 400  ARG A NE    1 
ATOM   6485  C  CZ    . ARG C 2 400 ? 33.248  9.865   59.626  1.00 71.31  ? 400  ARG A CZ    1 
ATOM   6486  N  NH1   . ARG C 2 400 ? 32.768  10.776  58.788  1.00 61.35  ? 400  ARG A NH1   1 
ATOM   6487  N  NH2   . ARG C 2 400 ? 32.422  9.255   60.466  1.00 64.07  ? 400  ARG A NH2   1 
ATOM   6488  N  N     . LEU C 2 401 ? 39.322  14.340  57.994  1.00 67.09  ? 401  LEU A N     1 
ATOM   6489  C  CA    . LEU C 2 401 ? 39.827  15.494  57.279  1.00 65.41  ? 401  LEU A CA    1 
ATOM   6490  C  C     . LEU C 2 401 ? 41.246  15.252  56.807  1.00 64.52  ? 401  LEU A C     1 
ATOM   6491  O  O     . LEU C 2 401 ? 41.590  15.612  55.690  1.00 60.13  ? 401  LEU A O     1 
ATOM   6492  C  CB    . LEU C 2 401 ? 39.765  16.744  58.167  1.00 66.49  ? 401  LEU A CB    1 
ATOM   6493  C  CG    . LEU C 2 401 ? 38.638  17.772  57.990  1.00 66.12  ? 401  LEU A CG    1 
ATOM   6494  C  CD1   . LEU C 2 401 ? 37.276  17.122  57.790  1.00 71.20  ? 401  LEU A CD1   1 
ATOM   6495  C  CD2   . LEU C 2 401 ? 38.626  18.645  59.229  1.00 74.52  ? 401  LEU A CD2   1 
ATOM   6496  N  N     . ARG C 2 402 ? 42.077  14.634  57.636  1.00 68.81  ? 402  ARG A N     1 
ATOM   6497  C  CA    . ARG C 2 402 ? 43.448  14.410  57.200  1.00 73.02  ? 402  ARG A CA    1 
ATOM   6498  C  C     . ARG C 2 402 ? 43.472  13.407  56.052  1.00 70.30  ? 402  ARG A C     1 
ATOM   6499  O  O     . ARG C 2 402 ? 44.500  13.241  55.399  1.00 59.17  ? 402  ARG A O     1 
ATOM   6500  C  CB    . ARG C 2 402 ? 44.339  13.942  58.357  1.00 75.17  ? 402  ARG A CB    1 
ATOM   6501  C  CG    . ARG C 2 402 ? 45.834  14.219  58.123  1.00 79.42  ? 402  ARG A CG    1 
ATOM   6502  C  CD    . ARG C 2 402 ? 46.550  14.512  59.442  1.00 89.89  ? 402  ARG A CD    1 
ATOM   6503  N  NE    . ARG C 2 402 ? 48.005  14.347  59.357  1.00 104.12 ? 402  ARG A NE    1 
ATOM   6504  C  CZ    . ARG C 2 402 ? 48.841  14.327  60.403  1.00 108.04 ? 402  ARG A CZ    1 
ATOM   6505  N  NH1   . ARG C 2 402 ? 48.384  14.468  61.648  1.00 100.82 ? 402  ARG A NH1   1 
ATOM   6506  N  NH2   . ARG C 2 402 ? 50.147  14.141  60.207  1.00 104.57 ? 402  ARG A NH2   1 
ATOM   6507  N  N     . ALA C 2 403 ? 42.316  12.791  55.792  1.00 67.60  ? 403  ALA A N     1 
ATOM   6508  C  CA    . ALA C 2 403 ? 42.150  11.793  54.729  1.00 76.19  ? 403  ALA A CA    1 
ATOM   6509  C  C     . ALA C 2 403 ? 41.636  12.374  53.411  1.00 78.22  ? 403  ALA A C     1 
ATOM   6510  O  O     . ALA C 2 403 ? 41.920  11.845  52.331  1.00 80.76  ? 403  ALA A O     1 
ATOM   6511  C  CB    . ALA C 2 403 ? 41.199  10.684  55.195  1.00 69.17  ? 403  ALA A CB    1 
ATOM   6512  N  N     . GLN C 2 404 ? 40.853  13.444  53.502  1.00 79.31  ? 404  GLN A N     1 
ATOM   6513  C  CA    . GLN C 2 404 ? 40.302  14.103  52.322  1.00 74.02  ? 404  GLN A CA    1 
ATOM   6514  C  C     . GLN C 2 404 ? 41.474  14.528  51.439  1.00 75.37  ? 404  GLN A C     1 
ATOM   6515  O  O     . GLN C 2 404 ? 42.280  15.359  51.854  1.00 74.16  ? 404  GLN A O     1 
ATOM   6516  C  CB    . GLN C 2 404 ? 39.515  15.339  52.752  1.00 74.27  ? 404  GLN A CB    1 
ATOM   6517  C  CG    . GLN C 2 404 ? 38.132  15.446  52.172  1.00 75.96  ? 404  GLN A CG    1 
ATOM   6518  C  CD    . GLN C 2 404 ? 38.088  15.042  50.722  1.00 82.16  ? 404  GLN A CD    1 
ATOM   6519  O  OE1   . GLN C 2 404 ? 39.072  15.187  49.993  1.00 88.27  ? 404  GLN A OE1   1 
ATOM   6520  N  NE2   . GLN C 2 404 ? 36.941  14.535  50.285  1.00 81.65  ? 404  GLN A NE2   1 
ATOM   6521  N  N     . GLU C 2 405 ? 41.588  13.974  50.234  1.00 78.32  ? 405  GLU A N     1 
ATOM   6522  C  CA    . GLU C 2 405 ? 42.714  14.353  49.378  1.00 84.48  ? 405  GLU A CA    1 
ATOM   6523  C  C     . GLU C 2 405 ? 42.422  15.630  48.590  1.00 84.96  ? 405  GLU A C     1 
ATOM   6524  O  O     . GLU C 2 405 ? 43.309  16.478  48.430  1.00 80.51  ? 405  GLU A O     1 
ATOM   6525  C  CB    . GLU C 2 405 ? 43.103  13.204  48.426  1.00 92.23  ? 405  GLU A CB    1 
ATOM   6526  C  CG    . GLU C 2 405 ? 44.480  13.385  47.724  1.00 97.52  ? 405  GLU A CG    1 
ATOM   6527  C  CD    . GLU C 2 405 ? 44.942  12.152  46.918  1.00 101.92 ? 405  GLU A CD    1 
ATOM   6528  O  OE1   . GLU C 2 405 ? 45.203  11.088  47.529  1.00 92.76  ? 405  GLU A OE1   1 
ATOM   6529  O  OE2   . GLU C 2 405 ? 45.047  12.248  45.671  1.00 99.86  ? 405  GLU A OE2   1 
ATOM   6530  N  N     . GLU C 2 406 ? 41.188  15.775  48.108  1.00 83.17  ? 406  GLU A N     1 
ATOM   6531  C  CA    . GLU C 2 406 ? 40.812  16.974  47.360  1.00 85.14  ? 406  GLU A CA    1 
ATOM   6532  C  C     . GLU C 2 406 ? 40.290  18.061  48.303  1.00 83.01  ? 406  GLU A C     1 
ATOM   6533  O  O     . GLU C 2 406 ? 39.137  18.042  48.738  1.00 78.18  ? 406  GLU A O     1 
ATOM   6534  C  CB    . GLU C 2 406 ? 39.757  16.653  46.302  1.00 84.70  ? 406  GLU A CB    1 
ATOM   6535  C  CG    . GLU C 2 406 ? 38.546  15.929  46.841  1.00 98.28  ? 406  GLU A CG    1 
ATOM   6536  C  CD    . GLU C 2 406 ? 37.385  15.930  45.864  1.00 107.11 ? 406  GLU A CD    1 
ATOM   6537  O  OE1   . GLU C 2 406 ? 36.469  15.094  46.040  1.00 112.29 ? 406  GLU A OE1   1 
ATOM   6538  O  OE2   . GLU C 2 406 ? 37.383  16.769  44.931  1.00 106.40 ? 406  GLU A OE2   1 
ATOM   6539  N  N     . TRP C 2 407 ? 41.159  19.015  48.607  1.00 80.39  ? 407  TRP A N     1 
ATOM   6540  C  CA    . TRP C 2 407 ? 40.813  20.103  49.500  1.00 81.49  ? 407  TRP A CA    1 
ATOM   6541  C  C     . TRP C 2 407 ? 40.138  21.268  48.761  1.00 77.37  ? 407  TRP A C     1 
ATOM   6542  O  O     . TRP C 2 407 ? 40.769  22.283  48.452  1.00 69.79  ? 407  TRP A O     1 
ATOM   6543  C  CB    . TRP C 2 407 ? 42.079  20.570  50.230  1.00 89.84  ? 407  TRP A CB    1 
ATOM   6544  C  CG    . TRP C 2 407 ? 41.807  21.216  51.557  1.00 99.44  ? 407  TRP A CG    1 
ATOM   6545  C  CD1   . TRP C 2 407 ? 41.533  22.531  51.790  1.00 102.59 ? 407  TRP A CD1   1 
ATOM   6546  C  CD2   . TRP C 2 407 ? 41.746  20.563  52.832  1.00 100.77 ? 407  TRP A CD2   1 
ATOM   6547  N  NE1   . TRP C 2 407 ? 41.305  22.739  53.130  1.00 103.92 ? 407  TRP A NE1   1 
ATOM   6548  C  CE2   . TRP C 2 407 ? 41.427  21.548  53.792  1.00 99.85  ? 407  TRP A CE2   1 
ATOM   6549  C  CE3   . TRP C 2 407 ? 41.923  19.240  53.255  1.00 100.05 ? 407  TRP A CE3   1 
ATOM   6550  C  CZ2   . TRP C 2 407 ? 41.287  21.256  55.146  1.00 99.38  ? 407  TRP A CZ2   1 
ATOM   6551  C  CZ3   . TRP C 2 407 ? 41.784  18.950  54.602  1.00 102.74 ? 407  TRP A CZ3   1 
ATOM   6552  C  CH2   . TRP C 2 407 ? 41.467  19.956  55.532  1.00 103.13 ? 407  TRP A CH2   1 
ATOM   6553  N  N     . THR C 2 408 ? 38.844  21.105  48.485  1.00 74.08  ? 408  THR A N     1 
ATOM   6554  C  CA    . THR C 2 408 ? 38.057  22.120  47.794  1.00 71.81  ? 408  THR A CA    1 
ATOM   6555  C  C     . THR C 2 408 ? 36.777  22.463  48.551  1.00 71.25  ? 408  THR A C     1 
ATOM   6556  O  O     . THR C 2 408 ? 36.265  21.671  49.337  1.00 67.61  ? 408  THR A O     1 
ATOM   6557  C  CB    . THR C 2 408 ? 37.659  21.665  46.370  1.00 74.38  ? 408  THR A CB    1 
ATOM   6558  O  OG1   . THR C 2 408 ? 36.765  20.547  46.450  1.00 67.35  ? 408  THR A OG1   1 
ATOM   6559  C  CG2   . THR C 2 408 ? 38.902  21.281  45.568  1.00 73.89  ? 408  THR A CG2   1 
ATOM   6560  N  N     . GLU C 2 409 ? 36.250  23.650  48.282  1.00 72.66  ? 409  GLU A N     1 
ATOM   6561  C  CA    . GLU C 2 409 ? 35.045  24.121  48.942  1.00 69.58  ? 409  GLU A CA    1 
ATOM   6562  C  C     . GLU C 2 409 ? 33.807  23.275  48.636  1.00 67.79  ? 409  GLU A C     1 
ATOM   6563  O  O     . GLU C 2 409 ? 32.823  23.328  49.378  1.00 61.76  ? 409  GLU A O     1 
ATOM   6564  C  CB    . GLU C 2 409 ? 34.812  25.586  48.568  1.00 72.65  ? 409  GLU A CB    1 
ATOM   6565  C  CG    . GLU C 2 409 ? 36.074  26.429  48.720  1.00 82.82  ? 409  GLU A CG    1 
ATOM   6566  C  CD    . GLU C 2 409 ? 35.883  27.893  48.353  1.00 91.71  ? 409  GLU A CD    1 
ATOM   6567  O  OE1   . GLU C 2 409 ? 36.871  28.652  48.469  1.00 87.96  ? 409  GLU A OE1   1 
ATOM   6568  O  OE2   . GLU C 2 409 ? 34.760  28.288  47.953  1.00 97.57  ? 409  GLU A OE2   1 
ATOM   6569  N  N     . ALA C 2 410 ? 33.843  22.507  47.548  1.00 65.49  ? 410  ALA A N     1 
ATOM   6570  C  CA    . ALA C 2 410 ? 32.706  21.655  47.202  1.00 66.03  ? 410  ALA A CA    1 
ATOM   6571  C  C     . ALA C 2 410 ? 32.921  20.313  47.894  1.00 64.49  ? 410  ALA A C     1 
ATOM   6572  O  O     . ALA C 2 410 ? 32.013  19.771  48.525  1.00 58.95  ? 410  ALA A O     1 
ATOM   6573  C  CB    . ALA C 2 410 ? 32.606  21.472  45.694  1.00 67.89  ? 410  ALA A CB    1 
ATOM   6574  N  N     . ALA C 2 411 ? 34.140  19.795  47.781  1.00 63.74  ? 411  ALA A N     1 
ATOM   6575  C  CA    . ALA C 2 411 ? 34.504  18.536  48.424  1.00 66.81  ? 411  ALA A CA    1 
ATOM   6576  C  C     . ALA C 2 411 ? 34.225  18.674  49.921  1.00 65.34  ? 411  ALA A C     1 
ATOM   6577  O  O     . ALA C 2 411 ? 33.390  17.959  50.477  1.00 71.31  ? 411  ALA A O     1 
ATOM   6578  C  CB    . ALA C 2 411 ? 36.001  18.225  48.191  1.00 55.29  ? 411  ALA A CB    1 
ATOM   6579  N  N     . LEU C 2 412 ? 34.917  19.616  50.560  1.00 61.56  ? 412  LEU A N     1 
ATOM   6580  C  CA    . LEU C 2 412 ? 34.764  19.843  51.991  1.00 52.86  ? 412  LEU A CA    1 
ATOM   6581  C  C     . LEU C 2 412 ? 33.321  20.007  52.429  1.00 52.38  ? 412  LEU A C     1 
ATOM   6582  O  O     . LEU C 2 412 ? 32.936  19.514  53.487  1.00 46.80  ? 412  LEU A O     1 
ATOM   6583  C  CB    . LEU C 2 412 ? 35.564  21.061  52.437  1.00 49.91  ? 412  LEU A CB    1 
ATOM   6584  C  CG    . LEU C 2 412 ? 37.084  20.999  52.649  1.00 48.12  ? 412  LEU A CG    1 
ATOM   6585  C  CD1   . LEU C 2 412 ? 37.442  19.844  53.544  1.00 49.50  ? 412  LEU A CD1   1 
ATOM   6586  C  CD2   . LEU C 2 412 ? 37.788  20.875  51.348  1.00 50.82  ? 412  LEU A CD2   1 
ATOM   6587  N  N     . GLU C 2 413 ? 32.507  20.688  51.631  1.00 53.70  ? 413  GLU A N     1 
ATOM   6588  C  CA    . GLU C 2 413 ? 31.121  20.858  52.039  1.00 54.75  ? 413  GLU A CA    1 
ATOM   6589  C  C     . GLU C 2 413 ? 30.459  19.501  52.073  1.00 59.13  ? 413  GLU A C     1 
ATOM   6590  O  O     . GLU C 2 413 ? 29.738  19.187  53.018  1.00 63.38  ? 413  GLU A O     1 
ATOM   6591  C  CB    . GLU C 2 413 ? 30.343  21.787  51.097  1.00 47.05  ? 413  GLU A CB    1 
ATOM   6592  C  CG    . GLU C 2 413 ? 28.849  21.887  51.452  1.00 49.94  ? 413  GLU A CG    1 
ATOM   6593  C  CD    . GLU C 2 413 ? 28.080  22.840  50.546  1.00 63.71  ? 413  GLU A CD    1 
ATOM   6594  O  OE1   . GLU C 2 413 ? 28.406  22.906  49.336  1.00 72.51  ? 413  GLU A OE1   1 
ATOM   6595  O  OE2   . GLU C 2 413 ? 27.140  23.512  51.033  1.00 48.93  ? 413  GLU A OE2   1 
ATOM   6596  N  N     . ALA C 2 414 ? 30.714  18.692  51.048  1.00 61.66  ? 414  ALA A N     1 
ATOM   6597  C  CA    . ALA C 2 414 ? 30.126  17.357  50.976  1.00 68.03  ? 414  ALA A CA    1 
ATOM   6598  C  C     . ALA C 2 414 ? 30.601  16.511  52.166  1.00 65.43  ? 414  ALA A C     1 
ATOM   6599  O  O     . ALA C 2 414 ? 29.796  15.852  52.837  1.00 70.86  ? 414  ALA A O     1 
ATOM   6600  C  CB    . ALA C 2 414 ? 30.494  16.683  49.645  1.00 63.10  ? 414  ALA A CB    1 
ATOM   6601  N  N     . LEU C 2 415 ? 31.905  16.545  52.428  1.00 56.76  ? 415  LEU A N     1 
ATOM   6602  C  CA    . LEU C 2 415 ? 32.492  15.813  53.551  1.00 57.46  ? 415  LEU A CA    1 
ATOM   6603  C  C     . LEU C 2 415 ? 31.823  16.188  54.892  1.00 60.65  ? 415  LEU A C     1 
ATOM   6604  O  O     . LEU C 2 415 ? 31.422  15.315  55.667  1.00 56.01  ? 415  LEU A O     1 
ATOM   6605  C  CB    . LEU C 2 415 ? 33.993  16.115  53.645  1.00 51.37  ? 415  LEU A CB    1 
ATOM   6606  C  CG    . LEU C 2 415 ? 34.721  15.195  54.625  1.00 59.32  ? 415  LEU A CG    1 
ATOM   6607  C  CD1   . LEU C 2 415 ? 34.754  13.804  54.005  1.00 63.01  ? 415  LEU A CD1   1 
ATOM   6608  C  CD2   . LEU C 2 415 ? 36.138  15.667  54.916  1.00 47.71  ? 415  LEU A CD2   1 
ATOM   6609  N  N     . LEU C 2 416 ? 31.692  17.488  55.150  1.00 55.70  ? 416  LEU A N     1 
ATOM   6610  C  CA    . LEU C 2 416 ? 31.101  17.952  56.398  1.00 60.15  ? 416  LEU A CA    1 
ATOM   6611  C  C     . LEU C 2 416 ? 29.603  17.716  56.486  1.00 62.11  ? 416  LEU A C     1 
ATOM   6612  O  O     . LEU C 2 416 ? 29.075  17.449  57.565  1.00 59.80  ? 416  LEU A O     1 
ATOM   6613  C  CB    . LEU C 2 416 ? 31.408  19.436  56.614  1.00 55.23  ? 416  LEU A CB    1 
ATOM   6614  C  CG    . LEU C 2 416 ? 32.893  19.789  56.699  1.00 54.62  ? 416  LEU A CG    1 
ATOM   6615  C  CD1   . LEU C 2 416 ? 33.046  21.285  56.804  1.00 69.37  ? 416  LEU A CD1   1 
ATOM   6616  C  CD2   . LEU C 2 416 ? 33.535  19.114  57.878  1.00 54.56  ? 416  LEU A CD2   1 
ATOM   6617  N  N     . ARG C 2 417 ? 28.908  17.832  55.362  1.00 66.93  ? 417  ARG A N     1 
ATOM   6618  C  CA    . ARG C 2 417 ? 27.464  17.595  55.350  1.00 70.43  ? 417  ARG A CA    1 
ATOM   6619  C  C     . ARG C 2 417 ? 27.231  16.121  55.723  1.00 68.68  ? 417  ARG A C     1 
ATOM   6620  O  O     . ARG C 2 417 ? 26.388  15.802  56.557  1.00 66.88  ? 417  ARG A O     1 
ATOM   6621  C  CB    . ARG C 2 417 ? 26.886  17.871  53.950  1.00 74.11  ? 417  ARG A CB    1 
ATOM   6622  C  CG    . ARG C 2 417 ? 26.927  19.325  53.488  1.00 67.15  ? 417  ARG A CG    1 
ATOM   6623  C  CD    . ARG C 2 417 ? 25.653  20.058  53.819  1.00 63.16  ? 417  ARG A CD    1 
ATOM   6624  N  NE    . ARG C 2 417 ? 25.747  21.465  53.442  1.00 67.46  ? 417  ARG A NE    1 
ATOM   6625  C  CZ    . ARG C 2 417 ? 24.866  22.400  53.796  1.00 67.09  ? 417  ARG A CZ    1 
ATOM   6626  N  NH1   . ARG C 2 417 ? 23.808  22.082  54.537  1.00 60.75  ? 417  ARG A NH1   1 
ATOM   6627  N  NH2   . ARG C 2 417 ? 25.057  23.661  53.434  1.00 62.95  ? 417  ARG A NH2   1 
ATOM   6628  N  N     . GLY C 2 418 ? 27.994  15.231  55.098  1.00 68.45  ? 418  GLY A N     1 
ATOM   6629  C  CA    . GLY C 2 418 ? 27.850  13.818  55.380  1.00 72.03  ? 418  GLY A CA    1 
ATOM   6630  C  C     . GLY C 2 418 ? 28.114  13.497  56.838  1.00 71.12  ? 418  GLY A C     1 
ATOM   6631  O  O     . GLY C 2 418 ? 27.318  12.832  57.503  1.00 71.48  ? 418  GLY A O     1 
ATOM   6632  N  N     . PHE C 2 419 ? 29.246  13.975  57.335  1.00 70.30  ? 419  PHE A N     1 
ATOM   6633  C  CA    . PHE C 2 419 ? 29.641  13.747  58.717  1.00 68.50  ? 419  PHE A CA    1 
ATOM   6634  C  C     . PHE C 2 419 ? 28.557  14.173  59.704  1.00 66.99  ? 419  PHE A C     1 
ATOM   6635  O  O     . PHE C 2 419 ? 28.255  13.447  60.648  1.00 68.55  ? 419  PHE A O     1 
ATOM   6636  C  CB    . PHE C 2 419 ? 30.944  14.496  58.988  1.00 67.00  ? 419  PHE A CB    1 
ATOM   6637  C  CG    . PHE C 2 419 ? 31.435  14.385  60.391  1.00 66.24  ? 419  PHE A CG    1 
ATOM   6638  C  CD1   . PHE C 2 419 ? 30.892  15.171  61.396  1.00 58.16  ? 419  PHE A CD1   1 
ATOM   6639  C  CD2   . PHE C 2 419 ? 32.474  13.519  60.707  1.00 70.61  ? 419  PHE A CD2   1 
ATOM   6640  C  CE1   . PHE C 2 419 ? 31.382  15.096  62.699  1.00 62.93  ? 419  PHE A CE1   1 
ATOM   6641  C  CE2   . PHE C 2 419 ? 32.969  13.439  62.009  1.00 70.04  ? 419  PHE A CE2   1 
ATOM   6642  C  CZ    . PHE C 2 419 ? 32.421  14.230  63.005  1.00 61.78  ? 419  PHE A CZ    1 
ATOM   6643  N  N     . ALA C 2 420 ? 27.969  15.343  59.491  1.00 67.00  ? 420  ALA A N     1 
ATOM   6644  C  CA    . ALA C 2 420 ? 26.921  15.831  60.389  1.00 70.36  ? 420  ALA A CA    1 
ATOM   6645  C  C     . ALA C 2 420 ? 25.710  14.926  60.284  1.00 67.48  ? 420  ALA A C     1 
ATOM   6646  O  O     . ALA C 2 420 ? 25.029  14.649  61.272  1.00 64.34  ? 420  ALA A O     1 
ATOM   6647  C  CB    . ALA C 2 420 ? 26.531  17.266  60.033  1.00 69.24  ? 420  ALA A CB    1 
ATOM   6648  N  N     . ALA C 2 421 ? 25.440  14.478  59.068  1.00 67.54  ? 421  ALA A N     1 
ATOM   6649  C  CA    . ALA C 2 421 ? 24.314  13.593  58.826  1.00 70.98  ? 421  ALA A CA    1 
ATOM   6650  C  C     . ALA C 2 421 ? 24.561  12.302  59.593  1.00 69.66  ? 421  ALA A C     1 
ATOM   6651  O  O     . ALA C 2 421 ? 23.780  11.920  60.472  1.00 62.67  ? 421  ALA A O     1 
ATOM   6652  C  CB    . ALA C 2 421 ? 24.183  13.303  57.326  1.00 70.24  ? 421  ALA A CB    1 
ATOM   6653  N  N     . GLU C 2 422 ? 25.668  11.644  59.265  1.00 68.33  ? 422  GLU A N     1 
ATOM   6654  C  CA    . GLU C 2 422 ? 26.017  10.394  59.913  1.00 71.05  ? 422  GLU A CA    1 
ATOM   6655  C  C     . GLU C 2 422 ? 26.115  10.540  61.432  1.00 72.35  ? 422  GLU A C     1 
ATOM   6656  O  O     . GLU C 2 422 ? 26.134  9.545   62.149  1.00 77.60  ? 422  GLU A O     1 
ATOM   6657  C  CB    . GLU C 2 422 ? 27.335  9.858   59.373  1.00 69.65  ? 422  GLU A CB    1 
ATOM   6658  C  CG    . GLU C 2 422 ? 28.536  10.456  60.032  1.00 71.85  ? 422  GLU A CG    1 
ATOM   6659  C  CD    . GLU C 2 422 ? 29.701  9.519   60.000  1.00 69.46  ? 422  GLU A CD    1 
ATOM   6660  O  OE1   . GLU C 2 422 ? 30.269  9.316   58.909  1.00 68.86  ? 422  GLU A OE1   1 
ATOM   6661  O  OE2   . GLU C 2 422 ? 30.042  8.977   61.070  1.00 77.75  ? 422  GLU A OE2   1 
ATOM   6662  N  N     . LYS C 2 423 ? 26.187  11.776  61.917  1.00 70.88  ? 423  LYS A N     1 
ATOM   6663  C  CA    . LYS C 2 423 ? 26.268  12.026  63.352  1.00 67.74  ? 423  LYS A CA    1 
ATOM   6664  C  C     . LYS C 2 423 ? 24.937  12.498  63.920  1.00 66.60  ? 423  LYS A C     1 
ATOM   6665  O  O     . LYS C 2 423 ? 24.813  12.736  65.124  1.00 59.59  ? 423  LYS A O     1 
ATOM   6666  C  CB    . LYS C 2 423 ? 27.350  13.059  63.652  1.00 69.90  ? 423  LYS A CB    1 
ATOM   6667  C  CG    . LYS C 2 423 ? 28.724  12.449  63.835  1.00 71.36  ? 423  LYS A CG    1 
ATOM   6668  C  CD    . LYS C 2 423 ? 28.728  11.526  65.035  1.00 66.37  ? 423  LYS A CD    1 
ATOM   6669  C  CE    . LYS C 2 423 ? 30.138  11.164  65.458  1.00 69.47  ? 423  LYS A CE    1 
ATOM   6670  N  NZ    . LYS C 2 423 ? 30.145  10.367  66.724  1.00 69.48  ? 423  LYS A NZ    1 
ATOM   6671  N  N     . GLY C 2 424 ? 23.943  12.624  63.044  1.00 67.97  ? 424  GLY A N     1 
ATOM   6672  C  CA    . GLY C 2 424 ? 22.621  13.052  63.467  1.00 68.82  ? 424  GLY A CA    1 
ATOM   6673  C  C     . GLY C 2 424 ? 22.631  14.388  64.178  1.00 72.01  ? 424  GLY A C     1 
ATOM   6674  O  O     . GLY C 2 424 ? 21.900  14.611  65.147  1.00 67.97  ? 424  GLY A O     1 
ATOM   6675  N  N     . VAL C 2 425 ? 23.469  15.290  63.686  1.00 73.20  ? 425  VAL A N     1 
ATOM   6676  C  CA    . VAL C 2 425 ? 23.586  16.613  64.270  1.00 67.75  ? 425  VAL A CA    1 
ATOM   6677  C  C     . VAL C 2 425 ? 23.459  17.629  63.132  1.00 65.00  ? 425  VAL A C     1 
ATOM   6678  O  O     . VAL C 2 425 ? 23.655  17.280  61.968  1.00 69.99  ? 425  VAL A O     1 
ATOM   6679  C  CB    . VAL C 2 425 ? 24.952  16.753  64.995  1.00 68.38  ? 425  VAL A CB    1 
ATOM   6680  C  CG1   . VAL C 2 425 ? 26.005  17.327  64.045  1.00 65.95  ? 425  VAL A CG1   1 
ATOM   6681  C  CG2   . VAL C 2 425 ? 24.793  17.583  66.253  1.00 59.91  ? 425  VAL A CG2   1 
ATOM   6682  N  N     . LYS C 2 426 ? 23.113  18.870  63.459  1.00 66.52  ? 426  LYS A N     1 
ATOM   6683  C  CA    . LYS C 2 426 ? 22.966  19.920  62.441  1.00 64.94  ? 426  LYS A CA    1 
ATOM   6684  C  C     . LYS C 2 426 ? 24.360  20.418  62.037  1.00 59.54  ? 426  LYS A C     1 
ATOM   6685  O  O     . LYS C 2 426 ? 25.242  20.529  62.888  1.00 56.19  ? 426  LYS A O     1 
ATOM   6686  C  CB    . LYS C 2 426 ? 22.154  21.088  63.007  1.00 63.27  ? 426  LYS A CB    1 
ATOM   6687  C  CG    . LYS C 2 426 ? 21.168  20.694  64.096  1.00 67.43  ? 426  LYS A CG    1 
ATOM   6688  C  CD    . LYS C 2 426 ? 20.449  21.917  64.665  1.00 73.44  ? 426  LYS A CD    1 
ATOM   6689  C  CE    . LYS C 2 426 ? 19.521  22.583  63.641  1.00 73.90  ? 426  LYS A CE    1 
ATOM   6690  N  NZ    . LYS C 2 426 ? 18.824  23.791  64.203  1.00 73.72  ? 426  LYS A NZ    1 
ATOM   6691  N  N     . LEU C 2 427 ? 24.558  20.721  60.754  1.00 58.10  ? 427  LEU A N     1 
ATOM   6692  C  CA    . LEU C 2 427 ? 25.862  21.200  60.283  1.00 56.80  ? 427  LEU A CA    1 
ATOM   6693  C  C     . LEU C 2 427 ? 26.435  22.255  61.227  1.00 56.08  ? 427  LEU A C     1 
ATOM   6694  O  O     . LEU C 2 427 ? 27.610  22.211  61.594  1.00 53.26  ? 427  LEU A O     1 
ATOM   6695  C  CB    . LEU C 2 427 ? 25.743  21.788  58.871  1.00 53.03  ? 427  LEU A CB    1 
ATOM   6696  C  CG    . LEU C 2 427 ? 27.043  22.370  58.290  1.00 58.67  ? 427  LEU A CG    1 
ATOM   6697  C  CD1   . LEU C 2 427 ? 28.117  21.288  58.237  1.00 45.51  ? 427  LEU A CD1   1 
ATOM   6698  C  CD2   . LEU C 2 427 ? 26.791  22.959  56.899  1.00 49.50  ? 427  LEU A CD2   1 
ATOM   6699  N  N     . GLY C 2 428 ? 25.594  23.203  61.620  1.00 57.87  ? 428  GLY A N     1 
ATOM   6700  C  CA    . GLY C 2 428 ? 26.047  24.247  62.512  1.00 54.98  ? 428  GLY A CA    1 
ATOM   6701  C  C     . GLY C 2 428 ? 26.718  23.673  63.734  1.00 63.13  ? 428  GLY A C     1 
ATOM   6702  O  O     . GLY C 2 428 ? 27.671  24.253  64.251  1.00 69.71  ? 428  GLY A O     1 
ATOM   6703  N  N     . GLN C 2 429 ? 26.230  22.530  64.206  1.00 61.89  ? 429  GLN A N     1 
ATOM   6704  C  CA    . GLN C 2 429 ? 26.805  21.905  65.390  1.00 61.27  ? 429  GLN A CA    1 
ATOM   6705  C  C     . GLN C 2 429 ? 28.245  21.510  65.138  1.00 54.34  ? 429  GLN A C     1 
ATOM   6706  O  O     . GLN C 2 429 ? 29.004  21.285  66.080  1.00 46.43  ? 429  GLN A O     1 
ATOM   6707  C  CB    . GLN C 2 429 ? 25.999  20.669  65.799  1.00 74.29  ? 429  GLN A CB    1 
ATOM   6708  C  CG    . GLN C 2 429 ? 24.644  20.950  66.480  1.00 86.56  ? 429  GLN A CG    1 
ATOM   6709  C  CD    . GLN C 2 429 ? 24.732  21.026  68.007  1.00 89.48  ? 429  GLN A CD    1 
ATOM   6710  O  OE1   . GLN C 2 429 ? 23.796  20.630  68.712  1.00 87.20  ? 429  GLN A OE1   1 
ATOM   6711  N  NE2   . GLN C 2 429 ? 25.849  21.544  68.521  1.00 88.97  ? 429  GLN A NE2   1 
ATOM   6712  N  N     . VAL C 2 430 ? 28.622  21.410  63.868  1.00 51.94  ? 430  VAL A N     1 
ATOM   6713  C  CA    . VAL C 2 430 ? 29.999  21.057  63.543  1.00 56.42  ? 430  VAL A CA    1 
ATOM   6714  C  C     . VAL C 2 430 ? 30.751  22.227  62.898  1.00 53.03  ? 430  VAL A C     1 
ATOM   6715  O  O     . VAL C 2 430 ? 31.941  22.416  63.131  1.00 49.96  ? 430  VAL A O     1 
ATOM   6716  C  CB    . VAL C 2 430 ? 30.064  19.830  62.627  1.00 58.52  ? 430  VAL A CB    1 
ATOM   6717  C  CG1   . VAL C 2 430 ? 29.535  20.173  61.248  1.00 64.63  ? 430  VAL A CG1   1 
ATOM   6718  C  CG2   . VAL C 2 430 ? 31.487  19.340  62.557  1.00 56.76  ? 430  VAL A CG2   1 
ATOM   6719  N  N     . ALA C 2 431 ? 30.042  23.023  62.109  1.00 49.87  ? 431  ALA A N     1 
ATOM   6720  C  CA    . ALA C 2 431 ? 30.635  24.187  61.459  1.00 51.78  ? 431  ALA A CA    1 
ATOM   6721  C  C     . ALA C 2 431 ? 31.063  25.288  62.452  1.00 48.25  ? 431  ALA A C     1 
ATOM   6722  O  O     . ALA C 2 431 ? 32.167  25.811  62.372  1.00 53.64  ? 431  ALA A O     1 
ATOM   6723  C  CB    . ALA C 2 431 ? 29.652  24.765  60.439  1.00 47.03  ? 431  ALA A CB    1 
ATOM   6724  N  N     . GLN C 2 432 ? 30.204  25.634  63.401  1.00 50.13  ? 432  GLN A N     1 
ATOM   6725  C  CA    . GLN C 2 432 ? 30.546  26.695  64.342  1.00 45.85  ? 432  GLN A CA    1 
ATOM   6726  C  C     . GLN C 2 432 ? 31.804  26.395  65.165  1.00 43.91  ? 432  GLN A C     1 
ATOM   6727  O  O     . GLN C 2 432 ? 32.719  27.221  65.235  1.00 47.46  ? 432  GLN A O     1 
ATOM   6728  C  CB    . GLN C 2 432 ? 29.345  27.008  65.244  1.00 36.94  ? 432  GLN A CB    1 
ATOM   6729  C  CG    . GLN C 2 432 ? 29.312  28.452  65.732  1.00 63.35  ? 432  GLN A CG    1 
ATOM   6730  C  CD    . GLN C 2 432 ? 29.092  29.511  64.625  1.00 60.16  ? 432  GLN A CD    1 
ATOM   6731  O  OE1   . GLN C 2 432 ? 29.851  29.612  63.656  1.00 45.65  ? 432  GLN A OE1   1 
ATOM   6732  N  NE2   . GLN C 2 432 ? 28.054  30.313  64.796  1.00 63.83  ? 432  GLN A NE2   1 
ATOM   6733  N  N     . PRO C 2 433 ? 31.881  25.215  65.804  1.00 45.07  ? 433  PRO A N     1 
ATOM   6734  C  CA    . PRO C 2 433 ? 33.104  24.948  66.581  1.00 37.74  ? 433  PRO A CA    1 
ATOM   6735  C  C     . PRO C 2 433 ? 34.357  24.941  65.687  1.00 37.86  ? 433  PRO A C     1 
ATOM   6736  O  O     . PRO C 2 433 ? 35.431  25.384  66.107  1.00 41.39  ? 433  PRO A O     1 
ATOM   6737  C  CB    . PRO C 2 433 ? 32.823  23.592  67.233  1.00 37.03  ? 433  PRO A CB    1 
ATOM   6738  C  CG    . PRO C 2 433 ? 31.824  22.942  66.304  1.00 43.67  ? 433  PRO A CG    1 
ATOM   6739  C  CD    . PRO C 2 433 ? 30.926  24.096  65.899  1.00 43.68  ? 433  PRO A CD    1 
ATOM   6740  N  N     . LEU C 2 434 ? 34.223  24.467  64.449  1.00 37.74  ? 434  LEU A N     1 
ATOM   6741  C  CA    . LEU C 2 434 ? 35.365  24.454  63.530  1.00 41.68  ? 434  LEU A CA    1 
ATOM   6742  C  C     . LEU C 2 434 ? 35.737  25.897  63.175  1.00 38.01  ? 434  LEU A C     1 
ATOM   6743  O  O     . LEU C 2 434 ? 36.931  26.257  63.152  1.00 33.03  ? 434  LEU A O     1 
ATOM   6744  C  CB    . LEU C 2 434 ? 35.049  23.666  62.255  1.00 40.27  ? 434  LEU A CB    1 
ATOM   6745  C  CG    . LEU C 2 434 ? 36.205  23.526  61.262  1.00 41.56  ? 434  LEU A CG    1 
ATOM   6746  C  CD1   . LEU C 2 434 ? 37.403  22.881  61.918  1.00 37.09  ? 434  LEU A CD1   1 
ATOM   6747  C  CD2   . LEU C 2 434 ? 35.749  22.704  60.077  1.00 40.81  ? 434  LEU A CD2   1 
ATOM   6748  N  N     . ARG C 2 435 ? 34.721  26.726  62.930  1.00 29.77  ? 435  ARG A N     1 
ATOM   6749  C  CA    . ARG C 2 435 ? 34.974  28.129  62.614  1.00 31.78  ? 435  ARG A CA    1 
ATOM   6750  C  C     . ARG C 2 435 ? 35.808  28.719  63.751  1.00 35.31  ? 435  ARG A C     1 
ATOM   6751  O  O     . ARG C 2 435 ? 36.813  29.381  63.512  1.00 34.76  ? 435  ARG A O     1 
ATOM   6752  C  CB    . ARG C 2 435 ? 33.676  28.922  62.461  1.00 23.64  ? 435  ARG A CB    1 
ATOM   6753  C  CG    . ARG C 2 435 ? 33.901  30.377  62.066  1.00 38.11  ? 435  ARG A CG    1 
ATOM   6754  C  CD    . ARG C 2 435 ? 32.595  31.207  61.924  1.00 30.41  ? 435  ARG A CD    1 
ATOM   6755  N  NE    . ARG C 2 435 ? 31.457  30.358  61.635  1.00 42.32  ? 435  ARG A NE    1 
ATOM   6756  C  CZ    . ARG C 2 435 ? 31.035  29.998  60.430  1.00 42.46  ? 435  ARG A CZ    1 
ATOM   6757  N  NH1   . ARG C 2 435 ? 31.629  30.408  59.321  1.00 37.01  ? 435  ARG A NH1   1 
ATOM   6758  N  NH2   . ARG C 2 435 ? 30.003  29.180  60.353  1.00 49.35  ? 435  ARG A NH2   1 
ATOM   6759  N  N     . ALA C 2 436 ? 35.409  28.452  64.991  1.00 37.12  ? 436  ALA A N     1 
ATOM   6760  C  CA    . ALA C 2 436 ? 36.155  28.972  66.149  1.00 41.01  ? 436  ALA A CA    1 
ATOM   6761  C  C     . ALA C 2 436 ? 37.590  28.462  66.174  1.00 36.87  ? 436  ALA A C     1 
ATOM   6762  O  O     . ALA C 2 436 ? 38.494  29.162  66.585  1.00 35.03  ? 436  ALA A O     1 
ATOM   6763  C  CB    . ALA C 2 436 ? 35.448  28.578  67.464  1.00 39.66  ? 436  ALA A CB    1 
ATOM   6764  N  N     . ALA C 2 437 ? 37.791  27.226  65.739  1.00 39.26  ? 437  ALA A N     1 
ATOM   6765  C  CA    . ALA C 2 437 ? 39.125  26.649  65.753  1.00 38.96  ? 437  ALA A CA    1 
ATOM   6766  C  C     . ALA C 2 437 ? 40.042  27.322  64.733  1.00 42.42  ? 437  ALA A C     1 
ATOM   6767  O  O     . ALA C 2 437 ? 41.200  27.628  65.020  1.00 40.53  ? 437  ALA A O     1 
ATOM   6768  C  CB    . ALA C 2 437 ? 39.030  25.156  65.479  1.00 33.29  ? 437  ALA A CB    1 
ATOM   6769  N  N     . LEU C 2 438 ? 39.504  27.552  63.546  1.00 31.87  ? 438  LEU A N     1 
ATOM   6770  C  CA    . LEU C 2 438 ? 40.242  28.161  62.470  1.00 32.68  ? 438  LEU A CA    1 
ATOM   6771  C  C     . LEU C 2 438 ? 40.448  29.659  62.576  1.00 38.69  ? 438  LEU A C     1 
ATOM   6772  O  O     . LEU C 2 438 ? 41.472  30.178  62.113  1.00 37.16  ? 438  LEU A O     1 
ATOM   6773  C  CB    . LEU C 2 438 ? 39.523  27.891  61.157  1.00 31.61  ? 438  LEU A CB    1 
ATOM   6774  C  CG    . LEU C 2 438 ? 39.442  26.419  60.808  1.00 44.26  ? 438  LEU A CG    1 
ATOM   6775  C  CD1   . LEU C 2 438 ? 38.544  26.208  59.597  1.00 45.88  ? 438  LEU A CD1   1 
ATOM   6776  C  CD2   . LEU C 2 438 ? 40.859  25.921  60.547  1.00 44.16  ? 438  LEU A CD2   1 
ATOM   6777  N  N     . THR C 2 439 ? 39.501  30.353  63.204  1.00 37.63  ? 439  THR A N     1 
ATOM   6778  C  CA    . THR C 2 439 ? 39.568  31.812  63.252  1.00 37.59  ? 439  THR A CA    1 
ATOM   6779  C  C     . THR C 2 439 ? 39.544  32.500  64.615  1.00 43.82  ? 439  THR A C     1 
ATOM   6780  O  O     . THR C 2 439 ? 39.846  33.693  64.716  1.00 33.83  ? 439  THR A O     1 
ATOM   6781  C  CB    . THR C 2 439 ? 38.417  32.396  62.441  1.00 34.32  ? 439  THR A CB    1 
ATOM   6782  O  OG1   . THR C 2 439 ? 37.221  32.353  63.234  1.00 32.72  ? 439  THR A OG1   1 
ATOM   6783  C  CG2   . THR C 2 439 ? 38.190  31.569  61.153  1.00 31.70  ? 439  THR A CG2   1 
ATOM   6784  N  N     . GLY C 2 440 ? 39.165  31.767  65.660  1.00 50.99  ? 440  GLY A N     1 
ATOM   6785  C  CA    . GLY C 2 440 ? 39.112  32.361  66.991  1.00 41.20  ? 440  GLY A CA    1 
ATOM   6786  C  C     . GLY C 2 440 ? 37.946  33.325  67.093  1.00 36.81  ? 440  GLY A C     1 
ATOM   6787  O  O     . GLY C 2 440 ? 37.912  34.175  67.982  1.00 35.55  ? 440  GLY A O     1 
ATOM   6788  N  N     . SER C 2 441 ? 36.998  33.186  66.166  1.00 36.67  ? 441  SER A N     1 
ATOM   6789  C  CA    . SER C 2 441 ? 35.798  34.020  66.111  1.00 32.32  ? 441  SER A CA    1 
ATOM   6790  C  C     . SER C 2 441 ? 34.582  33.269  65.562  1.00 35.96  ? 441  SER A C     1 
ATOM   6791  O  O     . SER C 2 441 ? 34.720  32.283  64.822  1.00 38.02  ? 441  SER A O     1 
ATOM   6792  C  CB    . SER C 2 441 ? 36.043  35.242  65.221  1.00 43.60  ? 441  SER A CB    1 
ATOM   6793  O  OG    . SER C 2 441 ? 34.811  35.855  64.844  1.00 44.58  ? 441  SER A OG    1 
ATOM   6794  N  N     . LEU C 2 442 ? 33.391  33.749  65.910  1.00 33.45  ? 442  LEU A N     1 
ATOM   6795  C  CA    . LEU C 2 442 ? 32.153  33.138  65.440  1.00 35.60  ? 442  LEU A CA    1 
ATOM   6796  C  C     . LEU C 2 442 ? 31.493  34.032  64.393  1.00 41.04  ? 442  LEU A C     1 
ATOM   6797  O  O     . LEU C 2 442 ? 30.381  33.754  63.948  1.00 45.10  ? 442  LEU A O     1 
ATOM   6798  C  CB    . LEU C 2 442 ? 31.162  32.898  66.600  1.00 40.74  ? 442  LEU A CB    1 
ATOM   6799  C  CG    . LEU C 2 442 ? 31.135  31.657  67.528  1.00 46.08  ? 442  LEU A CG    1 
ATOM   6800  C  CD1   . LEU C 2 442 ? 31.841  30.454  66.867  1.00 48.21  ? 442  LEU A CD1   1 
ATOM   6801  C  CD2   . LEU C 2 442 ? 31.789  31.982  68.862  1.00 42.69  ? 442  LEU A CD2   1 
ATOM   6802  N  N     . GLU C 2 443 ? 32.183  35.103  64.005  1.00 44.60  ? 443  GLU A N     1 
ATOM   6803  C  CA    . GLU C 2 443 ? 31.685  36.049  62.991  1.00 48.59  ? 443  GLU A CA    1 
ATOM   6804  C  C     . GLU C 2 443 ? 32.719  36.099  61.854  1.00 47.97  ? 443  GLU A C     1 
ATOM   6805  O  O     . GLU C 2 443 ? 33.652  36.910  61.879  1.00 48.16  ? 443  GLU A O     1 
ATOM   6806  C  CB    . GLU C 2 443 ? 31.528  37.452  63.593  1.00 49.09  ? 443  GLU A CB    1 
ATOM   6807  C  CG    . GLU C 2 443 ? 30.548  37.543  64.761  1.00 68.34  ? 443  GLU A CG    1 
ATOM   6808  C  CD    . GLU C 2 443 ? 30.381  38.975  65.301  1.00 82.34  ? 443  GLU A CD    1 
ATOM   6809  O  OE1   . GLU C 2 443 ? 29.520  39.178  66.188  1.00 92.16  ? 443  GLU A OE1   1 
ATOM   6810  O  OE2   . GLU C 2 443 ? 31.103  39.896  64.847  1.00 75.89  ? 443  GLU A OE2   1 
ATOM   6811  N  N     . THR C 2 444 ? 32.556  35.241  60.853  1.00 42.62  ? 444  THR A N     1 
ATOM   6812  C  CA    . THR C 2 444 ? 33.524  35.170  59.754  1.00 31.75  ? 444  THR A CA    1 
ATOM   6813  C  C     . THR C 2 444 ? 32.805  34.868  58.452  1.00 35.39  ? 444  THR A C     1 
ATOM   6814  O  O     . THR C 2 444 ? 31.583  34.868  58.398  1.00 29.79  ? 444  THR A O     1 
ATOM   6815  C  CB    . THR C 2 444 ? 34.484  33.981  59.952  1.00 28.10  ? 444  THR A CB    1 
ATOM   6816  O  OG1   . THR C 2 444 ? 33.801  32.760  59.584  1.00 19.89  ? 444  THR A OG1   1 
ATOM   6817  C  CG2   . THR C 2 444 ? 34.935  33.879  61.403  1.00 23.68  ? 444  THR A CG2   1 
ATOM   6818  N  N     . PRO C 2 445 ? 33.567  34.668  57.364  1.00 33.55  ? 445  PRO A N     1 
ATOM   6819  C  CA    . PRO C 2 445 ? 32.886  34.335  56.110  1.00 32.19  ? 445  PRO A CA    1 
ATOM   6820  C  C     . PRO C 2 445 ? 32.604  32.833  56.148  1.00 36.73  ? 445  PRO A C     1 
ATOM   6821  O  O     . PRO C 2 445 ? 32.855  32.172  57.161  1.00 34.37  ? 445  PRO A O     1 
ATOM   6822  C  CB    . PRO C 2 445 ? 33.901  34.709  55.028  1.00 40.08  ? 445  PRO A CB    1 
ATOM   6823  C  CG    . PRO C 2 445 ? 35.215  34.764  55.755  1.00 45.31  ? 445  PRO A CG    1 
ATOM   6824  C  CD    . PRO C 2 445 ? 34.856  35.322  57.094  1.00 30.66  ? 445  PRO A CD    1 
ATOM   6825  N  N     . GLY C 2 446 ? 32.088  32.303  55.042  1.00 43.59  ? 446  GLY A N     1 
ATOM   6826  C  CA    . GLY C 2 446 ? 31.746  30.890  54.932  1.00 35.25  ? 446  GLY A CA    1 
ATOM   6827  C  C     . GLY C 2 446 ? 32.811  29.887  55.344  1.00 41.02  ? 446  GLY A C     1 
ATOM   6828  O  O     . GLY C 2 446 ? 33.980  29.970  54.949  1.00 32.20  ? 446  GLY A O     1 
ATOM   6829  N  N     . LEU C 2 447 ? 32.392  28.896  56.113  1.00 37.18  ? 447  LEU A N     1 
ATOM   6830  C  CA    . LEU C 2 447 ? 33.319  27.897  56.603  1.00 42.73  ? 447  LEU A CA    1 
ATOM   6831  C  C     . LEU C 2 447 ? 34.118  27.195  55.524  1.00 41.60  ? 447  LEU A C     1 
ATOM   6832  O  O     . LEU C 2 447 ? 35.327  26.991  55.661  1.00 42.41  ? 447  LEU A O     1 
ATOM   6833  C  CB    . LEU C 2 447 ? 32.579  26.847  57.443  1.00 43.60  ? 447  LEU A CB    1 
ATOM   6834  C  CG    . LEU C 2 447 ? 33.448  25.700  57.985  1.00 44.94  ? 447  LEU A CG    1 
ATOM   6835  C  CD1   . LEU C 2 447 ? 34.442  26.204  59.061  1.00 29.84  ? 447  LEU A CD1   1 
ATOM   6836  C  CD2   . LEU C 2 447 ? 32.530  24.637  58.542  1.00 37.11  ? 447  LEU A CD2   1 
ATOM   6837  N  N     . PHE C 2 448 ? 33.462  26.819  54.444  1.00 42.40  ? 448  PHE A N     1 
ATOM   6838  C  CA    . PHE C 2 448 ? 34.181  26.088  53.413  1.00 43.09  ? 448  PHE A CA    1 
ATOM   6839  C  C     . PHE C 2 448 ? 35.250  26.926  52.716  1.00 46.80  ? 448  PHE A C     1 
ATOM   6840  O  O     . PHE C 2 448 ? 36.340  26.416  52.418  1.00 35.49  ? 448  PHE A O     1 
ATOM   6841  C  CB    . PHE C 2 448 ? 33.175  25.498  52.439  1.00 37.53  ? 448  PHE A CB    1 
ATOM   6842  C  CG    . PHE C 2 448 ? 32.013  24.829  53.134  1.00 38.95  ? 448  PHE A CG    1 
ATOM   6843  C  CD1   . PHE C 2 448 ? 32.232  23.756  54.004  1.00 36.31  ? 448  PHE A CD1   1 
ATOM   6844  C  CD2   . PHE C 2 448 ? 30.712  25.319  52.978  1.00 44.06  ? 448  PHE A CD2   1 
ATOM   6845  C  CE1   . PHE C 2 448 ? 31.178  23.181  54.714  1.00 40.01  ? 448  PHE A CE1   1 
ATOM   6846  C  CE2   . PHE C 2 448 ? 29.639  24.758  53.680  1.00 46.33  ? 448  PHE A CE2   1 
ATOM   6847  C  CZ    . PHE C 2 448 ? 29.872  23.685  54.554  1.00 49.38  ? 448  PHE A CZ    1 
ATOM   6848  N  N     . GLU C 2 449 ? 34.969  28.206  52.476  1.00 38.79  ? 449  GLU A N     1 
ATOM   6849  C  CA    . GLU C 2 449 ? 35.979  29.039  51.832  1.00 42.05  ? 449  GLU A CA    1 
ATOM   6850  C  C     . GLU C 2 449 ? 37.072  29.355  52.835  1.00 40.67  ? 449  GLU A C     1 
ATOM   6851  O  O     . GLU C 2 449 ? 38.218  29.542  52.473  1.00 46.47  ? 449  GLU A O     1 
ATOM   6852  C  CB    . GLU C 2 449 ? 35.376  30.331  51.289  1.00 42.77  ? 449  GLU A CB    1 
ATOM   6853  C  CG    . GLU C 2 449 ? 34.181  30.795  52.054  1.00 60.15  ? 449  GLU A CG    1 
ATOM   6854  C  CD    . GLU C 2 449 ? 32.911  30.209  51.517  1.00 63.01  ? 449  GLU A CD    1 
ATOM   6855  O  OE1   . GLU C 2 449 ? 32.469  30.731  50.481  1.00 67.26  ? 449  GLU A OE1   1 
ATOM   6856  O  OE2   . GLU C 2 449 ? 32.371  29.237  52.114  1.00 67.88  ? 449  GLU A OE2   1 
ATOM   6857  N  N     . ILE C 2 450 ? 36.709  29.403  54.106  1.00 43.09  ? 450  ILE A N     1 
ATOM   6858  C  CA    . ILE C 2 450 ? 37.671  29.672  55.148  1.00 38.39  ? 450  ILE A CA    1 
ATOM   6859  C  C     . ILE C 2 450 ? 38.571  28.470  55.251  1.00 37.16  ? 450  ILE A C     1 
ATOM   6860  O  O     . ILE C 2 450 ? 39.777  28.616  55.421  1.00 44.61  ? 450  ILE A O     1 
ATOM   6861  C  CB    . ILE C 2 450 ? 36.982  29.914  56.511  1.00 39.26  ? 450  ILE A CB    1 
ATOM   6862  C  CG1   . ILE C 2 450 ? 36.473  31.354  56.594  1.00 48.64  ? 450  ILE A CG1   1 
ATOM   6863  C  CG2   . ILE C 2 450 ? 37.944  29.654  57.652  1.00 39.68  ? 450  ILE A CG2   1 
ATOM   6864  C  CD1   . ILE C 2 450 ? 37.567  32.401  56.588  1.00 56.09  ? 450  ILE A CD1   1 
ATOM   6865  N  N     . LEU C 2 451 ? 37.977  27.281  55.164  1.00 47.30  ? 451  LEU A N     1 
ATOM   6866  C  CA    . LEU C 2 451 ? 38.733  26.021  55.244  1.00 47.14  ? 451  LEU A CA    1 
ATOM   6867  C  C     . LEU C 2 451 ? 39.606  25.835  53.996  1.00 48.28  ? 451  LEU A C     1 
ATOM   6868  O  O     . LEU C 2 451 ? 40.770  25.436  54.087  1.00 47.98  ? 451  LEU A O     1 
ATOM   6869  C  CB    . LEU C 2 451 ? 37.785  24.825  55.369  1.00 50.16  ? 451  LEU A CB    1 
ATOM   6870  C  CG    . LEU C 2 451 ? 37.953  23.941  56.605  1.00 52.06  ? 451  LEU A CG    1 
ATOM   6871  C  CD1   . LEU C 2 451 ? 37.062  22.722  56.464  1.00 60.39  ? 451  LEU A CD1   1 
ATOM   6872  C  CD2   . LEU C 2 451 ? 39.390  23.515  56.761  1.00 48.41  ? 451  LEU A CD2   1 
ATOM   6873  N  N     . ALA C 2 452 ? 39.037  26.123  52.829  1.00 41.01  ? 452  ALA A N     1 
ATOM   6874  C  CA    . ALA C 2 452 ? 39.770  26.002  51.583  1.00 40.47  ? 452  ALA A CA    1 
ATOM   6875  C  C     . ALA C 2 452 ? 40.899  27.031  51.473  1.00 41.70  ? 452  ALA A C     1 
ATOM   6876  O  O     . ALA C 2 452 ? 42.005  26.712  51.054  1.00 49.16  ? 452  ALA A O     1 
ATOM   6877  C  CB    . ALA C 2 452 ? 38.813  26.149  50.395  1.00 33.76  ? 452  ALA A CB    1 
ATOM   6878  N  N     . LEU C 2 453 ? 40.637  28.257  51.887  1.00 45.07  ? 453  LEU A N     1 
ATOM   6879  C  CA    . LEU C 2 453 ? 41.628  29.325  51.755  1.00 50.21  ? 453  LEU A CA    1 
ATOM   6880  C  C     . LEU C 2 453 ? 43.068  29.006  52.141  1.00 49.69  ? 453  LEU A C     1 
ATOM   6881  O  O     . LEU C 2 453 ? 43.989  29.339  51.403  1.00 51.21  ? 453  LEU A O     1 
ATOM   6882  C  CB    . LEU C 2 453 ? 41.165  30.577  52.521  1.00 41.85  ? 453  LEU A CB    1 
ATOM   6883  C  CG    . LEU C 2 453 ? 41.524  31.958  51.942  1.00 44.31  ? 453  LEU A CG    1 
ATOM   6884  C  CD1   . LEU C 2 453 ? 41.059  33.085  52.891  1.00 24.49  ? 453  LEU A CD1   1 
ATOM   6885  C  CD2   . LEU C 2 453 ? 42.999  32.048  51.723  1.00 27.82  ? 453  LEU A CD2   1 
ATOM   6886  N  N     . LEU C 2 454 ? 43.285  28.355  53.273  1.00 52.14  ? 454  LEU A N     1 
ATOM   6887  C  CA    . LEU C 2 454 ? 44.667  28.110  53.689  1.00 63.16  ? 454  LEU A CA    1 
ATOM   6888  C  C     . LEU C 2 454 ? 45.359  26.845  53.159  1.00 65.35  ? 454  LEU A C     1 
ATOM   6889  O  O     . LEU C 2 454 ? 46.580  26.697  53.286  1.00 63.23  ? 454  LEU A O     1 
ATOM   6890  C  CB    . LEU C 2 454 ? 44.740  28.115  55.215  1.00 62.90  ? 454  LEU A CB    1 
ATOM   6891  C  CG    . LEU C 2 454 ? 43.861  29.141  55.938  1.00 80.58  ? 454  LEU A CG    1 
ATOM   6892  C  CD1   . LEU C 2 454 ? 44.221  29.160  57.444  1.00 85.19  ? 454  LEU A CD1   1 
ATOM   6893  C  CD2   . LEU C 2 454 ? 44.050  30.525  55.318  1.00 78.82  ? 454  LEU A CD2   1 
ATOM   6894  N  N     . GLY C 2 455 ? 44.582  25.946  52.558  1.00 69.52  ? 455  GLY A N     1 
ATOM   6895  C  CA    . GLY C 2 455 ? 45.135  24.697  52.070  1.00 68.58  ? 455  GLY A CA    1 
ATOM   6896  C  C     . GLY C 2 455 ? 45.139  23.695  53.216  1.00 70.60  ? 455  GLY A C     1 
ATOM   6897  O  O     . GLY C 2 455 ? 45.312  24.090  54.373  1.00 68.86  ? 455  GLY A O     1 
ATOM   6898  N  N     . LYS C 2 456 ? 44.942  22.414  52.902  1.00 68.87  ? 456  LYS A N     1 
ATOM   6899  C  CA    . LYS C 2 456 ? 44.918  21.338  53.898  1.00 63.94  ? 456  LYS A CA    1 
ATOM   6900  C  C     . LYS C 2 456 ? 45.936  21.464  55.037  1.00 59.67  ? 456  LYS A C     1 
ATOM   6901  O  O     . LYS C 2 456 ? 45.569  21.510  56.207  1.00 64.13  ? 456  LYS A O     1 
ATOM   6902  C  CB    . LYS C 2 456 ? 45.127  19.994  53.202  1.00 65.58  ? 456  LYS A CB    1 
ATOM   6903  C  CG    . LYS C 2 456 ? 45.068  18.785  54.123  1.00 69.53  ? 456  LYS A CG    1 
ATOM   6904  C  CD    . LYS C 2 456 ? 45.119  17.502  53.312  1.00 72.11  ? 456  LYS A CD    1 
ATOM   6905  C  CE    . LYS C 2 456 ? 44.543  16.323  54.082  1.00 73.75  ? 456  LYS A CE    1 
ATOM   6906  N  NZ    . LYS C 2 456 ? 44.531  15.072  53.271  1.00 73.47  ? 456  LYS A NZ    1 
ATOM   6907  N  N     . GLU C 2 457 ? 47.215  21.514  54.695  1.00 59.45  ? 457  GLU A N     1 
ATOM   6908  C  CA    . GLU C 2 457 ? 48.273  21.603  55.699  1.00 63.97  ? 457  GLU A CA    1 
ATOM   6909  C  C     . GLU C 2 457 ? 48.078  22.676  56.767  1.00 59.79  ? 457  GLU A C     1 
ATOM   6910  O  O     . GLU C 2 457 ? 48.021  22.374  57.954  1.00 55.10  ? 457  GLU A O     1 
ATOM   6911  C  CB    . GLU C 2 457 ? 49.629  21.817  55.014  1.00 73.39  ? 457  GLU A CB    1 
ATOM   6912  C  CG    . GLU C 2 457 ? 50.622  20.663  55.174  1.00 83.78  ? 457  GLU A CG    1 
ATOM   6913  C  CD    . GLU C 2 457 ? 50.135  19.349  54.562  1.00 91.37  ? 457  GLU A CD    1 
ATOM   6914  O  OE1   . GLU C 2 457 ? 49.109  18.802  55.031  1.00 86.49  ? 457  GLU A OE1   1 
ATOM   6915  O  OE2   . GLU C 2 457 ? 50.788  18.861  53.610  1.00 96.56  ? 457  GLU A OE2   1 
ATOM   6916  N  N     . ARG C 2 458 ? 48.000  23.932  56.340  1.00 62.82  ? 458  ARG A N     1 
ATOM   6917  C  CA    . ARG C 2 458 ? 47.826  25.046  57.270  1.00 61.88  ? 458  ARG A CA    1 
ATOM   6918  C  C     . ARG C 2 458 ? 46.536  24.901  58.091  1.00 54.35  ? 458  ARG A C     1 
ATOM   6919  O  O     . ARG C 2 458 ? 46.532  25.148  59.300  1.00 47.17  ? 458  ARG A O     1 
ATOM   6920  C  CB    . ARG C 2 458 ? 47.831  26.376  56.499  1.00 68.27  ? 458  ARG A CB    1 
ATOM   6921  C  CG    . ARG C 2 458 ? 48.937  27.362  56.925  1.00 83.20  ? 458  ARG A CG    1 
ATOM   6922  C  CD    . ARG C 2 458 ? 48.605  28.125  58.236  1.00 89.81  ? 458  ARG A CD    1 
ATOM   6923  N  NE    . ARG C 2 458 ? 48.000  29.447  58.005  1.00 91.03  ? 458  ARG A NE    1 
ATOM   6924  C  CZ    . ARG C 2 458 ? 48.650  30.516  57.531  1.00 90.21  ? 458  ARG A CZ    1 
ATOM   6925  N  NH1   . ARG C 2 458 ? 49.943  30.443  57.233  1.00 84.89  ? 458  ARG A NH1   1 
ATOM   6926  N  NH2   . ARG C 2 458 ? 48.005  31.662  57.342  1.00 75.29  ? 458  ARG A NH2   1 
ATOM   6927  N  N     . ALA C 2 459 ? 45.459  24.484  57.431  1.00 45.96  ? 459  ALA A N     1 
ATOM   6928  C  CA    . ALA C 2 459 ? 44.160  24.295  58.082  1.00 50.12  ? 459  ALA A CA    1 
ATOM   6929  C  C     . ALA C 2 459 ? 44.232  23.314  59.268  1.00 53.74  ? 459  ALA A C     1 
ATOM   6930  O  O     . ALA C 2 459 ? 43.883  23.661  60.399  1.00 45.93  ? 459  ALA A O     1 
ATOM   6931  C  CB    . ALA C 2 459 ? 43.124  23.810  57.045  1.00 38.01  ? 459  ALA A CB    1 
ATOM   6932  N  N     . LEU C 2 460 ? 44.694  22.093  58.998  1.00 60.90  ? 460  LEU A N     1 
ATOM   6933  C  CA    . LEU C 2 460 ? 44.812  21.066  60.027  1.00 61.57  ? 460  LEU A CA    1 
ATOM   6934  C  C     . LEU C 2 460 ? 45.791  21.469  61.129  1.00 58.03  ? 460  LEU A C     1 
ATOM   6935  O  O     . LEU C 2 460 ? 45.528  21.260  62.310  1.00 59.79  ? 460  LEU A O     1 
ATOM   6936  C  CB    . LEU C 2 460 ? 45.229  19.742  59.380  1.00 60.13  ? 460  LEU A CB    1 
ATOM   6937  C  CG    . LEU C 2 460 ? 44.211  19.277  58.323  1.00 65.94  ? 460  LEU A CG    1 
ATOM   6938  C  CD1   . LEU C 2 460 ? 44.733  18.041  57.568  1.00 59.39  ? 460  LEU A CD1   1 
ATOM   6939  C  CD2   . LEU C 2 460 ? 42.868  18.993  59.005  1.00 61.15  ? 460  LEU A CD2   1 
ATOM   6940  N  N     . ARG C 2 461 ? 46.908  22.067  60.743  1.00 57.27  ? 461  ARG A N     1 
ATOM   6941  C  CA    . ARG C 2 461 ? 47.915  22.504  61.701  1.00 59.23  ? 461  ARG A CA    1 
ATOM   6942  C  C     . ARG C 2 461 ? 47.238  23.360  62.764  1.00 60.22  ? 461  ARG A C     1 
ATOM   6943  O  O     . ARG C 2 461 ? 47.503  23.227  63.963  1.00 62.44  ? 461  ARG A O     1 
ATOM   6944  C  CB    . ARG C 2 461 ? 48.990  23.303  60.966  1.00 62.54  ? 461  ARG A CB    1 
ATOM   6945  C  CG    . ARG C 2 461 ? 50.342  23.342  61.661  1.00 76.31  ? 461  ARG A CG    1 
ATOM   6946  C  CD    . ARG C 2 461 ? 50.446  24.496  62.636  1.00 84.92  ? 461  ARG A CD    1 
ATOM   6947  N  NE    . ARG C 2 461 ? 50.265  25.781  61.964  1.00 95.01  ? 461  ARG A NE    1 
ATOM   6948  C  CZ    . ARG C 2 461 ? 50.521  26.966  62.514  1.00 98.99  ? 461  ARG A CZ    1 
ATOM   6949  N  NH1   . ARG C 2 461 ? 50.980  27.051  63.763  1.00 95.66  ? 461  ARG A NH1   1 
ATOM   6950  N  NH2   . ARG C 2 461 ? 50.314  28.072  61.808  1.00 97.08  ? 461  ARG A NH2   1 
ATOM   6951  N  N     . ARG C 2 462 ? 46.344  24.231  62.314  1.00 58.19  ? 462  ARG A N     1 
ATOM   6952  C  CA    . ARG C 2 462 ? 45.618  25.101  63.222  1.00 60.39  ? 462  ARG A CA    1 
ATOM   6953  C  C     . ARG C 2 462 ? 44.547  24.294  63.969  1.00 58.81  ? 462  ARG A C     1 
ATOM   6954  O  O     . ARG C 2 462 ? 44.344  24.479  65.168  1.00 54.72  ? 462  ARG A O     1 
ATOM   6955  C  CB    . ARG C 2 462 ? 44.985  26.257  62.438  1.00 60.54  ? 462  ARG A CB    1 
ATOM   6956  C  CG    . ARG C 2 462 ? 44.257  27.267  63.301  1.00 59.08  ? 462  ARG A CG    1 
ATOM   6957  C  CD    . ARG C 2 462 ? 43.932  28.536  62.537  1.00 58.73  ? 462  ARG A CD    1 
ATOM   6958  N  NE    . ARG C 2 462 ? 45.117  29.366  62.303  1.00 50.85  ? 462  ARG A NE    1 
ATOM   6959  C  CZ    . ARG C 2 462 ? 45.074  30.571  61.743  1.00 46.44  ? 462  ARG A CZ    1 
ATOM   6960  N  NH1   . ARG C 2 462 ? 43.902  31.080  61.362  1.00 37.13  ? 462  ARG A NH1   1 
ATOM   6961  N  NH2   . ARG C 2 462 ? 46.196  31.267  61.569  1.00 35.32  ? 462  ARG A NH2   1 
ATOM   6962  N  N     . LEU C 2 463 ? 43.879  23.387  63.265  1.00 52.39  ? 463  LEU A N     1 
ATOM   6963  C  CA    . LEU C 2 463 ? 42.861  22.579  63.895  1.00 46.92  ? 463  LEU A CA    1 
ATOM   6964  C  C     . LEU C 2 463 ? 43.484  21.770  65.009  1.00 51.87  ? 463  LEU A C     1 
ATOM   6965  O  O     . LEU C 2 463 ? 42.876  21.569  66.062  1.00 51.47  ? 463  LEU A O     1 
ATOM   6966  C  CB    . LEU C 2 463 ? 42.238  21.635  62.885  1.00 50.23  ? 463  LEU A CB    1 
ATOM   6967  C  CG    . LEU C 2 463 ? 40.787  21.231  63.166  1.00 48.57  ? 463  LEU A CG    1 
ATOM   6968  C  CD1   . LEU C 2 463 ? 40.432  20.075  62.243  1.00 52.07  ? 463  LEU A CD1   1 
ATOM   6969  C  CD2   . LEU C 2 463 ? 40.593  20.834  64.608  1.00 42.44  ? 463  LEU A CD2   1 
ATOM   6970  N  N     . GLU C 2 464 ? 44.708  21.311  64.775  1.00 57.19  ? 464  GLU A N     1 
ATOM   6971  C  CA    . GLU C 2 464 ? 45.423  20.507  65.749  1.00 58.90  ? 464  GLU A CA    1 
ATOM   6972  C  C     . GLU C 2 464 ? 45.723  21.252  67.035  1.00 61.99  ? 464  GLU A C     1 
ATOM   6973  O  O     . GLU C 2 464 ? 45.502  20.712  68.112  1.00 72.74  ? 464  GLU A O     1 
ATOM   6974  C  CB    . GLU C 2 464 ? 46.711  19.967  65.128  1.00 61.74  ? 464  GLU A CB    1 
ATOM   6975  C  CG    . GLU C 2 464 ? 46.426  18.987  63.995  1.00 68.57  ? 464  GLU A CG    1 
ATOM   6976  C  CD    . GLU C 2 464 ? 47.593  18.801  63.040  1.00 70.55  ? 464  GLU A CD    1 
ATOM   6977  O  OE1   . GLU C 2 464 ? 47.383  18.183  61.969  1.00 65.28  ? 464  GLU A OE1   1 
ATOM   6978  O  OE2   . GLU C 2 464 ? 48.709  19.271  63.359  1.00 58.70  ? 464  GLU A OE2   1 
ATOM   6979  N  N     . ARG C 2 465 ? 46.218  22.483  66.948  1.00 62.96  ? 465  ARG A N     1 
ATOM   6980  C  CA    . ARG C 2 465 ? 46.514  23.231  68.170  1.00 64.20  ? 465  ARG A CA    1 
ATOM   6981  C  C     . ARG C 2 465 ? 45.271  23.416  69.041  1.00 65.28  ? 465  ARG A C     1 
ATOM   6982  O  O     . ARG C 2 465 ? 45.375  23.603  70.250  1.00 69.64  ? 465  ARG A O     1 
ATOM   6983  C  CB    . ARG C 2 465 ? 47.097  24.601  67.838  1.00 66.62  ? 465  ARG A CB    1 
ATOM   6984  C  CG    . ARG C 2 465 ? 48.451  24.567  67.157  1.00 82.00  ? 465  ARG A CG    1 
ATOM   6985  C  CD    . ARG C 2 465 ? 49.033  25.977  67.083  1.00 88.89  ? 465  ARG A CD    1 
ATOM   6986  N  NE    . ARG C 2 465 ? 48.078  26.901  66.471  1.00 93.10  ? 465  ARG A NE    1 
ATOM   6987  C  CZ    . ARG C 2 465 ? 48.300  28.196  66.270  1.00 87.73  ? 465  ARG A CZ    1 
ATOM   6988  N  NH1   . ARG C 2 465 ? 49.456  28.738  66.634  1.00 85.73  ? 465  ARG A NH1   1 
ATOM   6989  N  NH2   . ARG C 2 465 ? 47.361  28.944  65.704  1.00 77.95  ? 465  ARG A NH2   1 
ATOM   6990  N  N     . ALA C 2 466 ? 44.094  23.368  68.423  1.00 64.94  ? 466  ALA A N     1 
ATOM   6991  C  CA    . ALA C 2 466 ? 42.838  23.539  69.148  1.00 65.64  ? 466  ALA A CA    1 
ATOM   6992  C  C     . ALA C 2 466 ? 42.430  22.233  69.810  1.00 66.20  ? 466  ALA A C     1 
ATOM   6993  O  O     . ALA C 2 466 ? 41.772  22.221  70.854  1.00 64.64  ? 466  ALA A O     1 
ATOM   6994  C  CB    . ALA C 2 466 ? 41.743  24.007  68.200  1.00 69.09  ? 466  ALA A CB    1 
ATOM   6995  N  N     . LEU C 2 467 ? 42.817  21.125  69.195  1.00 66.04  ? 467  LEU A N     1 
ATOM   6996  C  CA    . LEU C 2 467 ? 42.500  19.822  69.755  1.00 65.04  ? 467  LEU A CA    1 
ATOM   6997  C  C     . LEU C 2 467 ? 43.564  19.460  70.794  1.00 70.55  ? 467  LEU A C     1 
ATOM   6998  O  O     . LEU C 2 467 ? 43.398  18.527  71.577  1.00 68.64  ? 467  LEU A O     1 
ATOM   6999  C  CB    . LEU C 2 467 ? 42.470  18.768  68.656  1.00 55.74  ? 467  LEU A CB    1 
ATOM   7000  C  CG    . LEU C 2 467 ? 41.580  19.077  67.454  1.00 57.67  ? 467  LEU A CG    1 
ATOM   7001  C  CD1   . LEU C 2 467 ? 41.603  17.889  66.492  1.00 57.05  ? 467  LEU A CD1   1 
ATOM   7002  C  CD2   . LEU C 2 467 ? 40.161  19.373  67.915  1.00 55.41  ? 467  LEU A CD2   1 
ATOM   7003  N  N     . ALA C 2 468 ? 44.664  20.206  70.797  1.00 75.92  ? 468  ALA A N     1 
ATOM   7004  C  CA    . ALA C 2 468 ? 45.735  19.955  71.750  1.00 79.91  ? 468  ALA A CA    1 
ATOM   7005  C  C     . ALA C 2 468 ? 45.217  20.342  73.129  1.00 83.49  ? 468  ALA A C     1 
ATOM   7006  O  O     . ALA C 2 468 ? 45.247  19.480  74.039  1.00 85.45  ? 468  ALA A O     1 
ATOM   7007  C  CB    . ALA C 2 468 ? 46.972  20.777  71.392  1.00 72.74  ? 468  ALA A CB    1 
ATOM   7008  O  OXT   . ALA C 2 468 ? 44.774  21.505  73.273  1.00 87.50  ? 468  ALA A OXT   1 
ATOM   7009  N  N     . MET D 2 1   ? 88.827  84.297  91.259  1.00 83.60  ? 1    MET B N     1 
ATOM   7010  C  CA    . MET D 2 1   ? 88.066  83.092  91.733  1.00 80.18  ? 1    MET B CA    1 
ATOM   7011  C  C     . MET D 2 1   ? 88.020  82.937  93.271  1.00 71.98  ? 1    MET B C     1 
ATOM   7012  O  O     . MET D 2 1   ? 87.342  83.712  93.966  1.00 68.47  ? 1    MET B O     1 
ATOM   7013  C  CB    . MET D 2 1   ? 88.642  81.816  91.075  1.00 83.98  ? 1    MET B CB    1 
ATOM   7014  C  CG    . MET D 2 1   ? 90.086  81.942  90.529  1.00 88.39  ? 1    MET B CG    1 
ATOM   7015  S  SD    . MET D 2 1   ? 91.442  82.133  91.764  1.00 93.71  ? 1    MET B SD    1 
ATOM   7016  C  CE    . MET D 2 1   ? 92.247  80.496  91.670  1.00 84.61  ? 1    MET B CE    1 
ATOM   7017  N  N     . VAL D 2 2   ? 88.742  81.946  93.791  1.00 54.18  ? 2    VAL B N     1 
ATOM   7018  C  CA    . VAL D 2 2   ? 88.764  81.687  95.221  1.00 39.75  ? 2    VAL B CA    1 
ATOM   7019  C  C     . VAL D 2 2   ? 90.135  81.353  95.765  1.00 36.41  ? 2    VAL B C     1 
ATOM   7020  O  O     . VAL D 2 2   ? 90.784  80.427  95.302  1.00 35.55  ? 2    VAL B O     1 
ATOM   7021  C  CB    . VAL D 2 2   ? 87.834  80.513  95.590  1.00 36.41  ? 2    VAL B CB    1 
ATOM   7022  C  CG1   . VAL D 2 2   ? 88.055  80.095  97.032  1.00 26.54  ? 2    VAL B CG1   1 
ATOM   7023  C  CG2   . VAL D 2 2   ? 86.389  80.921  95.384  1.00 38.17  ? 2    VAL B CG2   1 
ATOM   7024  N  N     . VAL D 2 3   ? 90.561  82.104  96.771  1.00 34.43  ? 3    VAL B N     1 
ATOM   7025  C  CA    . VAL D 2 3   ? 91.830  81.854  97.428  1.00 24.84  ? 3    VAL B CA    1 
ATOM   7026  C  C     . VAL D 2 3   ? 91.601  81.844  98.943  1.00 29.72  ? 3    VAL B C     1 
ATOM   7027  O  O     . VAL D 2 3   ? 91.053  82.798  99.525  1.00 33.99  ? 3    VAL B O     1 
ATOM   7028  C  CB    . VAL D 2 3   ? 92.861  82.924  97.083  1.00 28.28  ? 3    VAL B CB    1 
ATOM   7029  C  CG1   . VAL D 2 3   ? 94.124  82.720  97.905  1.00 27.46  ? 3    VAL B CG1   1 
ATOM   7030  C  CG2   . VAL D 2 3   ? 93.186  82.867  95.620  1.00 25.68  ? 3    VAL B CG2   1 
ATOM   7031  N  N     . THR D 2 4   ? 92.007  80.746  99.565  1.00 29.55  ? 4    THR B N     1 
ATOM   7032  C  CA    . THR D 2 4   ? 91.906  80.566  101.003 1.00 20.80  ? 4    THR B CA    1 
ATOM   7033  C  C     . THR D 2 4   ? 93.307  80.405  101.550 1.00 31.44  ? 4    THR B C     1 
ATOM   7034  O  O     . THR D 2 4   ? 94.279  80.255  100.790 1.00 28.02  ? 4    THR B O     1 
ATOM   7035  C  CB    . THR D 2 4   ? 91.143  79.290  101.358 1.00 25.41  ? 4    THR B CB    1 
ATOM   7036  O  OG1   . THR D 2 4   ? 91.847  78.161  100.819 1.00 19.66  ? 4    THR B OG1   1 
ATOM   7037  C  CG2   . THR D 2 4   ? 89.697  79.335  100.789 1.00 11.69  ? 4    THR B CG2   1 
ATOM   7038  N  N     . ARG D 2 5   ? 93.424  80.444  102.873 1.00 31.90  ? 5    ARG B N     1 
ATOM   7039  C  CA    . ARG D 2 5   ? 94.724  80.236  103.495 1.00 31.54  ? 5    ARG B CA    1 
ATOM   7040  C  C     . ARG D 2 5   ? 94.666  79.700  104.914 1.00 32.28  ? 5    ARG B C     1 
ATOM   7041  O  O     . ARG D 2 5   ? 93.649  79.778  105.587 1.00 33.43  ? 5    ARG B O     1 
ATOM   7042  C  CB    . ARG D 2 5   ? 95.555  81.532  103.492 1.00 29.74  ? 5    ARG B CB    1 
ATOM   7043  C  CG    . ARG D 2 5   ? 94.849  82.792  103.944 1.00 34.34  ? 5    ARG B CG    1 
ATOM   7044  C  CD    . ARG D 2 5   ? 94.316  82.690  105.328 1.00 38.39  ? 5    ARG B CD    1 
ATOM   7045  N  NE    . ARG D 2 5   ? 93.958  83.988  105.884 1.00 39.97  ? 5    ARG B NE    1 
ATOM   7046  C  CZ    . ARG D 2 5   ? 93.604  84.165  107.155 1.00 35.84  ? 5    ARG B CZ    1 
ATOM   7047  N  NH1   . ARG D 2 5   ? 93.550  83.138  107.986 1.00 37.61  ? 5    ARG B NH1   1 
ATOM   7048  N  NH2   . ARG D 2 5   ? 93.342  85.364  107.609 1.00 29.88  ? 5    ARG B NH2   1 
ATOM   7049  N  N     . ILE D 2 6   ? 95.772  79.117  105.341 1.00 35.35  ? 6    ILE B N     1 
ATOM   7050  C  CA    . ILE D 2 6   ? 95.912  78.658  106.700 1.00 33.69  ? 6    ILE B CA    1 
ATOM   7051  C  C     . ILE D 2 6   ? 97.049  79.589  107.087 1.00 37.19  ? 6    ILE B C     1 
ATOM   7052  O  O     . ILE D 2 6   ? 97.902  79.914  106.244 1.00 42.36  ? 6    ILE B O     1 
ATOM   7053  C  CB    . ILE D 2 6   ? 96.335  77.165  106.794 1.00 40.63  ? 6    ILE B CB    1 
ATOM   7054  C  CG1   . ILE D 2 6   ? 96.268  76.727  108.253 1.00 47.75  ? 6    ILE B CG1   1 
ATOM   7055  C  CG2   . ILE D 2 6   ? 97.720  76.934  106.244 1.00 37.71  ? 6    ILE B CG2   1 
ATOM   7056  C  CD1   . ILE D 2 6   ? 94.838  76.781  108.840 1.00 44.23  ? 6    ILE B CD1   1 
ATOM   7057  N  N     . ALA D 2 7   ? 97.063  80.068  108.320 1.00 29.85  ? 7    ALA B N     1 
ATOM   7058  C  CA    . ALA D 2 7   ? 98.124  80.980  108.719 1.00 27.45  ? 7    ALA B CA    1 
ATOM   7059  C  C     . ALA D 2 7   ? 98.587  80.694  110.145 1.00 33.74  ? 7    ALA B C     1 
ATOM   7060  O  O     . ALA D 2 7   ? 98.419  81.512  111.047 1.00 31.85  ? 7    ALA B O     1 
ATOM   7061  C  CB    . ALA D 2 7   ? 97.631  82.411  108.590 1.00 28.26  ? 7    ALA B CB    1 
ATOM   7062  N  N     . PRO D 2 8   ? 99.202  79.528  110.364 1.00 36.27  ? 8    PRO B N     1 
ATOM   7063  C  CA    . PRO D 2 8   ? 99.672  79.156  111.699 1.00 35.52  ? 8    PRO B CA    1 
ATOM   7064  C  C     . PRO D 2 8   ? 100.878 79.936  112.187 1.00 35.94  ? 8    PRO B C     1 
ATOM   7065  O  O     . PRO D 2 8   ? 101.665 80.453  111.402 1.00 35.44  ? 8    PRO B O     1 
ATOM   7066  C  CB    . PRO D 2 8   ? 100.024 77.700  111.528 1.00 37.77  ? 8    PRO B CB    1 
ATOM   7067  C  CG    . PRO D 2 8   ? 100.696 77.748  110.158 1.00 33.92  ? 8    PRO B CG    1 
ATOM   7068  C  CD    . PRO D 2 8   ? 99.726  78.600  109.348 1.00 29.49  ? 8    PRO B CD    1 
ATOM   7069  N  N     . SER D 2 9   ? 101.009 79.981  113.503 1.00 47.31  ? 9    SER B N     1 
ATOM   7070  C  CA    . SER D 2 9   ? 102.131 80.615  114.176 1.00 57.58  ? 9    SER B CA    1 
ATOM   7071  C  C     . SER D 2 9   ? 102.999 79.447  114.653 1.00 65.24  ? 9    SER B C     1 
ATOM   7072  O  O     . SER D 2 9   ? 102.481 78.446  115.147 1.00 64.20  ? 9    SER B O     1 
ATOM   7073  C  CB    . SER D 2 9   ? 101.650 81.410  115.391 1.00 59.31  ? 9    SER B CB    1 
ATOM   7074  O  OG    . SER D 2 9   ? 100.730 82.422  115.014 1.00 60.38  ? 9    SER B OG    1 
ATOM   7075  N  N     . PRO D 2 10  ? 104.325 79.547  114.491 1.00 70.55  ? 10   PRO B N     1 
ATOM   7076  C  CA    . PRO D 2 10  ? 105.221 78.471  114.925 1.00 73.03  ? 10   PRO B CA    1 
ATOM   7077  C  C     . PRO D 2 10  ? 105.585 78.637  116.408 1.00 74.79  ? 10   PRO B C     1 
ATOM   7078  O  O     . PRO D 2 10  ? 106.675 79.101  116.742 1.00 76.16  ? 10   PRO B O     1 
ATOM   7079  C  CB    . PRO D 2 10  ? 106.449 78.648  114.021 1.00 74.69  ? 10   PRO B CB    1 
ATOM   7080  C  CG    . PRO D 2 10  ? 106.037 79.674  112.989 1.00 73.25  ? 10   PRO B CG    1 
ATOM   7081  C  CD    . PRO D 2 10  ? 105.067 80.544  113.709 1.00 70.50  ? 10   PRO B CD    1 
ATOM   7082  N  N     . THR D 2 11  ? 104.678 78.269  117.301 1.00 74.33  ? 11   THR B N     1 
ATOM   7083  C  CA    . THR D 2 11  ? 104.954 78.419  118.725 1.00 74.55  ? 11   THR B CA    1 
ATOM   7084  C  C     . THR D 2 11  ? 104.903 77.102  119.486 1.00 70.02  ? 11   THR B C     1 
ATOM   7085  O  O     . THR D 2 11  ? 104.910 77.102  120.719 1.00 70.72  ? 11   THR B O     1 
ATOM   7086  C  CB    . THR D 2 11  ? 103.956 79.413  119.406 1.00 79.31  ? 11   THR B CB    1 
ATOM   7087  O  OG1   . THR D 2 11  ? 102.626 78.887  119.329 1.00 78.66  ? 11   THR B OG1   1 
ATOM   7088  C  CG2   . THR D 2 11  ? 104.001 80.795  118.732 1.00 77.40  ? 11   THR B CG2   1 
ATOM   7089  N  N     . GLY D 2 12  ? 104.859 75.986  118.760 1.00 65.66  ? 12   GLY B N     1 
ATOM   7090  C  CA    . GLY D 2 12  ? 104.803 74.679  119.409 1.00 65.13  ? 12   GLY B CA    1 
ATOM   7091  C  C     . GLY D 2 12  ? 104.570 73.487  118.480 1.00 64.01  ? 12   GLY B C     1 
ATOM   7092  O  O     . GLY D 2 12  ? 104.852 73.561  117.273 1.00 63.49  ? 12   GLY B O     1 
ATOM   7093  N  N     . ASP D 2 13  ? 104.070 72.383  119.042 1.00 56.49  ? 13   ASP B N     1 
ATOM   7094  C  CA    . ASP D 2 13  ? 103.781 71.180  118.261 1.00 54.70  ? 13   ASP B CA    1 
ATOM   7095  C  C     . ASP D 2 13  ? 102.607 71.455  117.336 1.00 44.90  ? 13   ASP B C     1 
ATOM   7096  O  O     . ASP D 2 13  ? 101.717 72.206  117.681 1.00 46.37  ? 13   ASP B O     1 
ATOM   7097  C  CB    . ASP D 2 13  ? 103.347 70.003  119.147 1.00 63.47  ? 13   ASP B CB    1 
ATOM   7098  C  CG    . ASP D 2 13  ? 104.216 69.819  120.371 1.00 72.40  ? 13   ASP B CG    1 
ATOM   7099  O  OD1   . ASP D 2 13  ? 105.450 69.639  120.218 1.00 76.98  ? 13   ASP B OD1   1 
ATOM   7100  O  OD2   . ASP D 2 13  ? 103.651 69.841  121.490 1.00 69.53  ? 13   ASP B OD2   1 
ATOM   7101  N  N     . PRO D 2 14  ? 102.588 70.839  116.152 1.00 41.34  ? 14   PRO B N     1 
ATOM   7102  C  CA    . PRO D 2 14  ? 101.465 71.063  115.231 1.00 43.81  ? 14   PRO B CA    1 
ATOM   7103  C  C     . PRO D 2 14  ? 100.160 70.670  115.962 1.00 41.07  ? 14   PRO B C     1 
ATOM   7104  O  O     . PRO D 2 14  ? 100.019 69.566  116.479 1.00 32.30  ? 14   PRO B O     1 
ATOM   7105  C  CB    . PRO D 2 14  ? 101.803 70.165  114.041 1.00 37.39  ? 14   PRO B CB    1 
ATOM   7106  C  CG    . PRO D 2 14  ? 102.636 69.068  114.662 1.00 54.93  ? 14   PRO B CG    1 
ATOM   7107  C  CD    . PRO D 2 14  ? 103.502 69.799  115.649 1.00 47.33  ? 14   PRO B CD    1 
ATOM   7108  N  N     . HIS D 2 15  ? 99.220  71.601  115.995 1.00 37.09  ? 15   HIS B N     1 
ATOM   7109  C  CA    . HIS D 2 15  ? 97.968  71.448  116.727 1.00 35.58  ? 15   HIS B CA    1 
ATOM   7110  C  C     . HIS D 2 15  ? 96.795  70.942  115.852 1.00 34.85  ? 15   HIS B C     1 
ATOM   7111  O  O     . HIS D 2 15  ? 96.660  71.304  114.665 1.00 31.14  ? 15   HIS B O     1 
ATOM   7112  C  CB    . HIS D 2 15  ? 97.689  72.831  117.366 1.00 42.61  ? 15   HIS B CB    1 
ATOM   7113  C  CG    . HIS D 2 15  ? 96.598  72.868  118.398 1.00 53.11  ? 15   HIS B CG    1 
ATOM   7114  N  ND1   . HIS D 2 15  ? 95.276  72.591  118.110 1.00 50.56  ? 15   HIS B ND1   1 
ATOM   7115  C  CD2   . HIS D 2 15  ? 96.615  73.297  119.687 1.00 56.86  ? 15   HIS B CD2   1 
ATOM   7116  C  CE1   . HIS D 2 15  ? 94.529  72.855  119.170 1.00 53.93  ? 15   HIS B CE1   1 
ATOM   7117  N  NE2   . HIS D 2 15  ? 95.317  73.286  120.140 1.00 57.54  ? 15   HIS B NE2   1 
ATOM   7118  N  N     . VAL D 2 16  ? 95.946  70.115  116.456 1.00 22.55  ? 16   VAL B N     1 
ATOM   7119  C  CA    . VAL D 2 16  ? 94.786  69.537  115.783 1.00 23.67  ? 16   VAL B CA    1 
ATOM   7120  C  C     . VAL D 2 16  ? 93.814  70.622  115.322 1.00 25.81  ? 16   VAL B C     1 
ATOM   7121  O  O     . VAL D 2 16  ? 93.092  70.461  114.341 1.00 31.31  ? 16   VAL B O     1 
ATOM   7122  C  CB    . VAL D 2 16  ? 94.064  68.519  116.723 1.00 25.61  ? 16   VAL B CB    1 
ATOM   7123  C  CG1   . VAL D 2 16  ? 93.568  69.220  117.947 1.00 30.60  ? 16   VAL B CG1   1 
ATOM   7124  C  CG2   . VAL D 2 16  ? 92.917  67.855  116.004 1.00 39.25  ? 16   VAL B CG2   1 
ATOM   7125  N  N     . GLY D 2 17  ? 93.788  71.738  116.035 1.00 29.08  ? 17   GLY B N     1 
ATOM   7126  C  CA    . GLY D 2 17  ? 92.911  72.829  115.637 1.00 22.75  ? 17   GLY B CA    1 
ATOM   7127  C  C     . GLY D 2 17  ? 93.355  73.397  114.299 1.00 20.55  ? 17   GLY B C     1 
ATOM   7128  O  O     . GLY D 2 17  ? 92.539  73.873  113.531 1.00 24.49  ? 17   GLY B O     1 
ATOM   7129  N  N     . THR D 2 18  ? 94.650  73.334  114.001 1.00 26.09  ? 18   THR B N     1 
ATOM   7130  C  CA    . THR D 2 18  ? 95.151  73.857  112.731 1.00 30.96  ? 18   THR B CA    1 
ATOM   7131  C  C     . THR D 2 18  ? 94.744  72.848  111.655 1.00 32.96  ? 18   THR B C     1 
ATOM   7132  O  O     . THR D 2 18  ? 94.218  73.214  110.595 1.00 31.35  ? 18   THR B O     1 
ATOM   7133  C  CB    . THR D 2 18  ? 96.702  73.997  112.714 1.00 40.71  ? 18   THR B CB    1 
ATOM   7134  O  OG1   . THR D 2 18  ? 97.140  74.727  113.866 1.00 31.70  ? 18   THR B OG1   1 
ATOM   7135  C  CG2   . THR D 2 18  ? 97.152  74.730  111.455 1.00 38.90  ? 18   THR B CG2   1 
ATOM   7136  N  N     . ALA D 2 19  ? 94.954  71.575  111.947 1.00 20.71  ? 19   ALA B N     1 
ATOM   7137  C  CA    . ALA D 2 19  ? 94.586  70.543  110.982 1.00 30.32  ? 19   ALA B CA    1 
ATOM   7138  C  C     . ALA D 2 19  ? 93.155  70.778  110.586 1.00 26.83  ? 19   ALA B C     1 
ATOM   7139  O  O     . ALA D 2 19  ? 92.796  70.784  109.402 1.00 23.77  ? 19   ALA B O     1 
ATOM   7140  C  CB    . ALA D 2 19  ? 94.723  69.159  111.599 1.00 21.89  ? 19   ALA B CB    1 
ATOM   7141  N  N     . TYR D 2 20  ? 92.351  71.005  111.614 1.00 29.02  ? 20   TYR B N     1 
ATOM   7142  C  CA    . TYR D 2 20  ? 90.921  71.217  111.475 1.00 31.55  ? 20   TYR B CA    1 
ATOM   7143  C  C     . TYR D 2 20  ? 90.543  72.429  110.573 1.00 29.90  ? 20   TYR B C     1 
ATOM   7144  O  O     . TYR D 2 20  ? 89.783  72.288  109.618 1.00 19.46  ? 20   TYR B O     1 
ATOM   7145  C  CB    . TYR D 2 20  ? 90.352  71.326  112.883 1.00 25.05  ? 20   TYR B CB    1 
ATOM   7146  C  CG    . TYR D 2 20  ? 88.984  71.902  112.958 1.00 26.94  ? 20   TYR B CG    1 
ATOM   7147  C  CD1   . TYR D 2 20  ? 87.890  71.233  112.423 1.00 26.55  ? 20   TYR B CD1   1 
ATOM   7148  C  CD2   . TYR D 2 20  ? 88.772  73.104  113.602 1.00 26.77  ? 20   TYR B CD2   1 
ATOM   7149  C  CE1   . TYR D 2 20  ? 86.615  71.749  112.534 1.00 25.15  ? 20   TYR B CE1   1 
ATOM   7150  C  CE2   . TYR D 2 20  ? 87.502  73.634  113.723 1.00 36.41  ? 20   TYR B CE2   1 
ATOM   7151  C  CZ    . TYR D 2 20  ? 86.425  72.955  113.187 1.00 33.09  ? 20   TYR B CZ    1 
ATOM   7152  O  OH    . TYR D 2 20  ? 85.165  73.502  113.305 1.00 40.78  ? 20   TYR B OH    1 
ATOM   7153  N  N     . ILE D 2 21  ? 91.093  73.604  110.860 1.00 30.41  ? 21   ILE B N     1 
ATOM   7154  C  CA    . ILE D 2 21  ? 90.807  74.775  110.038 1.00 26.55  ? 21   ILE B CA    1 
ATOM   7155  C  C     . ILE D 2 21  ? 91.443  74.593  108.640 1.00 27.60  ? 21   ILE B C     1 
ATOM   7156  O  O     . ILE D 2 21  ? 90.868  75.010  107.626 1.00 23.22  ? 21   ILE B O     1 
ATOM   7157  C  CB    . ILE D 2 21  ? 91.327  76.088  110.714 1.00 26.97  ? 21   ILE B CB    1 
ATOM   7158  C  CG1   . ILE D 2 21  ? 90.212  76.776  111.506 1.00 28.56  ? 21   ILE B CG1   1 
ATOM   7159  C  CG2   . ILE D 2 21  ? 91.729  77.092  109.666 1.00 21.89  ? 21   ILE B CG2   1 
ATOM   7160  C  CD1   . ILE D 2 21  ? 89.750  76.061  112.711 1.00 36.21  ? 21   ILE B CD1   1 
ATOM   7161  N  N     . ALA D 2 22  ? 92.616  73.960  108.590 1.00 24.01  ? 22   ALA B N     1 
ATOM   7162  C  CA    . ALA D 2 22  ? 93.276  73.688  107.311 1.00 27.98  ? 22   ALA B CA    1 
ATOM   7163  C  C     . ALA D 2 22  ? 92.359  72.845  106.425 1.00 31.57  ? 22   ALA B C     1 
ATOM   7164  O  O     . ALA D 2 22  ? 92.168  73.121  105.248 1.00 30.63  ? 22   ALA B O     1 
ATOM   7165  C  CB    . ALA D 2 22  ? 94.587  72.935  107.537 1.00 24.21  ? 22   ALA B CB    1 
ATOM   7166  N  N     . LEU D 2 23  ? 91.786  71.807  107.016 1.00 37.66  ? 23   LEU B N     1 
ATOM   7167  C  CA    . LEU D 2 23  ? 90.914  70.904  106.300 1.00 22.42  ? 23   LEU B CA    1 
ATOM   7168  C  C     . LEU D 2 23  ? 89.778  71.609  105.582 1.00 32.38  ? 23   LEU B C     1 
ATOM   7169  O  O     . LEU D 2 23  ? 89.494  71.306  104.425 1.00 28.34  ? 23   LEU B O     1 
ATOM   7170  C  CB    . LEU D 2 23  ? 90.351  69.885  107.270 1.00 32.34  ? 23   LEU B CB    1 
ATOM   7171  C  CG    . LEU D 2 23  ? 89.402  68.865  106.665 1.00 32.96  ? 23   LEU B CG    1 
ATOM   7172  C  CD1   . LEU D 2 23  ? 90.173  68.006  105.690 1.00 34.85  ? 23   LEU B CD1   1 
ATOM   7173  C  CD2   . LEU D 2 23  ? 88.814  68.004  107.759 1.00 34.03  ? 23   LEU B CD2   1 
ATOM   7174  N  N     . PHE D 2 24  ? 89.109  72.549  106.251 1.00 34.27  ? 24   PHE B N     1 
ATOM   7175  C  CA    . PHE D 2 24  ? 87.997  73.244  105.594 1.00 30.88  ? 24   PHE B CA    1 
ATOM   7176  C  C     . PHE D 2 24  ? 88.480  74.289  104.562 1.00 34.32  ? 24   PHE B C     1 
ATOM   7177  O  O     . PHE D 2 24  ? 87.809  74.578  103.569 1.00 27.47  ? 24   PHE B O     1 
ATOM   7178  C  CB    . PHE D 2 24  ? 87.062  73.873  106.649 1.00 27.22  ? 24   PHE B CB    1 
ATOM   7179  C  CG    . PHE D 2 24  ? 86.121  72.885  107.288 1.00 25.55  ? 24   PHE B CG    1 
ATOM   7180  C  CD1   . PHE D 2 24  ? 86.563  72.028  108.292 1.00 24.61  ? 24   PHE B CD1   1 
ATOM   7181  C  CD2   . PHE D 2 24  ? 84.809  72.743  106.810 1.00 24.71  ? 24   PHE B CD2   1 
ATOM   7182  C  CE1   . PHE D 2 24  ? 85.714  71.015  108.811 1.00 21.74  ? 24   PHE B CE1   1 
ATOM   7183  C  CE2   . PHE D 2 24  ? 83.947  71.744  107.314 1.00 24.71  ? 24   PHE B CE2   1 
ATOM   7184  C  CZ    . PHE D 2 24  ? 84.409  70.874  108.317 1.00 23.65  ? 24   PHE B CZ    1 
ATOM   7185  N  N     . ASN D 2 25  ? 89.654  74.864  104.795 1.00 32.57  ? 25   ASN B N     1 
ATOM   7186  C  CA    . ASN D 2 25  ? 90.184  75.811  103.843 1.00 29.85  ? 25   ASN B CA    1 
ATOM   7187  C  C     . ASN D 2 25  ? 90.559  75.089  102.548 1.00 34.39  ? 25   ASN B C     1 
ATOM   7188  O  O     . ASN D 2 25  ? 90.251  75.561  101.441 1.00 28.19  ? 25   ASN B O     1 
ATOM   7189  C  CB    . ASN D 2 25  ? 91.398  76.502  104.420 1.00 28.90  ? 25   ASN B CB    1 
ATOM   7190  C  CG    . ASN D 2 25  ? 91.018  77.676  105.269 1.00 31.37  ? 25   ASN B CG    1 
ATOM   7191  O  OD1   . ASN D 2 25  ? 90.976  77.583  106.495 1.00 25.98  ? 25   ASN B OD1   1 
ATOM   7192  N  ND2   . ASN D 2 25  ? 90.714  78.798  104.616 1.00 21.88  ? 25   ASN B ND2   1 
ATOM   7193  N  N     . TYR D 2 26  ? 91.207  73.934  102.702 1.00 26.35  ? 26   TYR B N     1 
ATOM   7194  C  CA    . TYR D 2 26  ? 91.630  73.126  101.567 1.00 27.05  ? 26   TYR B CA    1 
ATOM   7195  C  C     . TYR D 2 26  ? 90.418  72.705  100.733 1.00 34.85  ? 26   TYR B C     1 
ATOM   7196  O  O     . TYR D 2 26  ? 90.410  72.834  99.490  1.00 26.27  ? 26   TYR B O     1 
ATOM   7197  C  CB    . TYR D 2 26  ? 92.409  71.906  102.071 1.00 16.63  ? 26   TYR B CB    1 
ATOM   7198  C  CG    . TYR D 2 26  ? 92.685  70.846  101.043 1.00 22.63  ? 26   TYR B CG    1 
ATOM   7199  C  CD1   . TYR D 2 26  ? 91.831  69.747  100.920 1.00 36.60  ? 26   TYR B CD1   1 
ATOM   7200  C  CD2   . TYR D 2 26  ? 93.797  70.920  100.194 1.00 20.89  ? 26   TYR B CD2   1 
ATOM   7201  C  CE1   . TYR D 2 26  ? 92.071  68.738  99.981  1.00 31.72  ? 26   TYR B CE1   1 
ATOM   7202  C  CE2   . TYR D 2 26  ? 94.052  69.915  99.245  1.00 25.66  ? 26   TYR B CE2   1 
ATOM   7203  C  CZ    . TYR D 2 26  ? 93.168  68.821  99.149  1.00 35.74  ? 26   TYR B CZ    1 
ATOM   7204  O  OH    . TYR D 2 26  ? 93.337  67.813  98.221  1.00 37.81  ? 26   TYR B OH    1 
ATOM   7205  N  N     . ALA D 2 27  ? 89.387  72.233  101.425 1.00 26.95  ? 27   ALA B N     1 
ATOM   7206  C  CA    . ALA D 2 27  ? 88.181  71.795  100.754 1.00 29.32  ? 27   ALA B CA    1 
ATOM   7207  C  C     . ALA D 2 27  ? 87.504  72.929  99.981  1.00 34.42  ? 27   ALA B C     1 
ATOM   7208  O  O     . ALA D 2 27  ? 87.182  72.774  98.794  1.00 29.34  ? 27   ALA B O     1 
ATOM   7209  C  CB    . ALA D 2 27  ? 87.224  71.207  101.757 1.00 24.27  ? 27   ALA B CB    1 
ATOM   7210  N  N     . TRP D 2 28  ? 87.325  74.082  100.614 1.00 25.76  ? 28   TRP B N     1 
ATOM   7211  C  CA    . TRP D 2 28  ? 86.639  75.167  99.915  1.00 29.88  ? 28   TRP B CA    1 
ATOM   7212  C  C     . TRP D 2 28  ? 87.440  75.634  98.699  1.00 31.80  ? 28   TRP B C     1 
ATOM   7213  O  O     . TRP D 2 28  ? 86.881  76.107  97.702  1.00 26.05  ? 28   TRP B O     1 
ATOM   7214  C  CB    . TRP D 2 28  ? 86.370  76.339  100.882 1.00 18.91  ? 28   TRP B CB    1 
ATOM   7215  C  CG    . TRP D 2 28  ? 85.530  77.444  100.341 1.00 22.05  ? 28   TRP B CG    1 
ATOM   7216  C  CD1   . TRP D 2 28  ? 85.844  78.771  100.347 1.00 24.67  ? 28   TRP B CD1   1 
ATOM   7217  C  CD2   . TRP D 2 28  ? 84.193  77.354  99.801  1.00 20.76  ? 28   TRP B CD2   1 
ATOM   7218  N  NE1   . TRP D 2 28  ? 84.799  79.513  99.862  1.00 23.25  ? 28   TRP B NE1   1 
ATOM   7219  C  CE2   . TRP D 2 28  ? 83.770  78.676  99.519  1.00 26.11  ? 28   TRP B CE2   1 
ATOM   7220  C  CE3   . TRP D 2 28  ? 83.323  76.291  99.522  1.00 17.81  ? 28   TRP B CE3   1 
ATOM   7221  C  CZ2   . TRP D 2 28  ? 82.495  78.974  98.981  1.00 22.08  ? 28   TRP B CZ2   1 
ATOM   7222  C  CZ3   . TRP D 2 28  ? 82.053  76.579  98.979  1.00 20.42  ? 28   TRP B CZ3   1 
ATOM   7223  C  CH2   . TRP D 2 28  ? 81.653  77.920  98.718  1.00 20.94  ? 28   TRP B CH2   1 
ATOM   7224  N  N     . ALA D 2 29  ? 88.759  75.523  98.775  1.00 33.12  ? 29   ALA B N     1 
ATOM   7225  C  CA    . ALA D 2 29  ? 89.558  75.943  97.636  1.00 35.42  ? 29   ALA B CA    1 
ATOM   7226  C  C     . ALA D 2 29  ? 89.334  74.946  96.491  1.00 37.49  ? 29   ALA B C     1 
ATOM   7227  O  O     . ALA D 2 29  ? 88.957  75.325  95.379  1.00 32.92  ? 29   ALA B O     1 
ATOM   7228  C  CB    . ALA D 2 29  ? 91.054  76.016  98.007  1.00 35.50  ? 29   ALA B CB    1 
ATOM   7229  N  N     . ARG D 2 30  ? 89.536  73.666  96.770  1.00 28.30  ? 30   ARG B N     1 
ATOM   7230  C  CA    . ARG D 2 30  ? 89.372  72.676  95.726  1.00 32.72  ? 30   ARG B CA    1 
ATOM   7231  C  C     . ARG D 2 30  ? 87.979  72.630  95.132  1.00 33.17  ? 30   ARG B C     1 
ATOM   7232  O  O     . ARG D 2 30  ? 87.833  72.560  93.928  1.00 37.15  ? 30   ARG B O     1 
ATOM   7233  C  CB    . ARG D 2 30  ? 89.776  71.308  96.246  1.00 31.53  ? 30   ARG B CB    1 
ATOM   7234  C  CG    . ARG D 2 30  ? 91.268  71.240  96.573  1.00 30.61  ? 30   ARG B CG    1 
ATOM   7235  C  CD    . ARG D 2 30  ? 92.160  71.129  95.328  1.00 29.06  ? 30   ARG B CD    1 
ATOM   7236  N  NE    . ARG D 2 30  ? 93.559  71.022  95.724  1.00 31.42  ? 30   ARG B NE    1 
ATOM   7237  C  CZ    . ARG D 2 30  ? 94.398  72.046  95.708  1.00 37.20  ? 30   ARG B CZ    1 
ATOM   7238  N  NH1   . ARG D 2 30  ? 93.980  73.244  95.295  1.00 36.76  ? 30   ARG B NH1   1 
ATOM   7239  N  NH2   . ARG D 2 30  ? 95.635  71.889  96.147  1.00 43.99  ? 30   ARG B NH2   1 
ATOM   7240  N  N     . ARG D 2 31  ? 86.958  72.701  95.975  1.00 33.08  ? 31   ARG B N     1 
ATOM   7241  C  CA    . ARG D 2 31  ? 85.575  72.648  95.512  1.00 28.02  ? 31   ARG B CA    1 
ATOM   7242  C  C     . ARG D 2 31  ? 85.298  73.734  94.474  1.00 36.07  ? 31   ARG B C     1 
ATOM   7243  O  O     . ARG D 2 31  ? 84.441  73.570  93.618  1.00 33.40  ? 31   ARG B O     1 
ATOM   7244  C  CB    . ARG D 2 31  ? 84.620  72.808  96.705  1.00 28.35  ? 31   ARG B CB    1 
ATOM   7245  C  CG    . ARG D 2 31  ? 83.141  72.938  96.346  1.00 32.83  ? 31   ARG B CG    1 
ATOM   7246  C  CD    . ARG D 2 31  ? 82.719  71.757  95.488  1.00 53.93  ? 31   ARG B CD    1 
ATOM   7247  N  NE    . ARG D 2 31  ? 81.465  71.995  94.787  1.00 61.50  ? 31   ARG B NE    1 
ATOM   7248  C  CZ    . ARG D 2 31  ? 80.264  71.733  95.294  1.00 74.05  ? 31   ARG B CZ    1 
ATOM   7249  N  NH1   . ARG D 2 31  ? 80.143  71.211  96.514  1.00 67.60  ? 31   ARG B NH1   1 
ATOM   7250  N  NH2   . ARG D 2 31  ? 79.180  72.006  94.579  1.00 74.96  ? 31   ARG B NH2   1 
ATOM   7251  N  N     . ASN D 2 32  ? 86.032  74.839  94.550  1.00 34.94  ? 32   ASN B N     1 
ATOM   7252  C  CA    . ASN D 2 32  ? 85.836  75.960  93.636  1.00 31.04  ? 32   ASN B CA    1 
ATOM   7253  C  C     . ASN D 2 32  ? 86.967  76.126  92.613  1.00 40.41  ? 32   ASN B C     1 
ATOM   7254  O  O     . ASN D 2 32  ? 87.040  77.145  91.919  1.00 34.83  ? 32   ASN B O     1 
ATOM   7255  C  CB    . ASN D 2 32  ? 85.712  77.248  94.445  1.00 42.47  ? 32   ASN B CB    1 
ATOM   7256  C  CG    . ASN D 2 32  ? 84.375  77.375  95.149  1.00 43.38  ? 32   ASN B CG    1 
ATOM   7257  O  OD1   . ASN D 2 32  ? 83.404  77.834  94.549  1.00 53.01  ? 32   ASN B OD1   1 
ATOM   7258  N  ND2   . ASN D 2 32  ? 84.314  76.968  96.423  1.00 42.57  ? 32   ASN B ND2   1 
ATOM   7259  N  N     . GLY D 2 33  ? 87.848  75.130  92.521  1.00 38.38  ? 33   GLY B N     1 
ATOM   7260  C  CA    . GLY D 2 33  ? 88.954  75.224  91.598  1.00 25.23  ? 33   GLY B CA    1 
ATOM   7261  C  C     . GLY D 2 33  ? 89.823  76.421  91.910  1.00 33.65  ? 33   GLY B C     1 
ATOM   7262  O  O     . GLY D 2 33  ? 90.351  77.069  91.000  1.00 34.30  ? 33   GLY B O     1 
ATOM   7263  N  N     . GLY D 2 34  ? 89.973  76.726  93.198  1.00 33.50  ? 34   GLY B N     1 
ATOM   7264  C  CA    . GLY D 2 34  ? 90.783  77.870  93.590  1.00 30.77  ? 34   GLY B CA    1 
ATOM   7265  C  C     . GLY D 2 34  ? 92.150  77.499  94.133  1.00 28.24  ? 34   GLY B C     1 
ATOM   7266  O  O     . GLY D 2 34  ? 92.664  76.420  93.873  1.00 35.97  ? 34   GLY B O     1 
ATOM   7267  N  N     . ARG D 2 35  ? 92.743  78.392  94.903  1.00 28.51  ? 35   ARG B N     1 
ATOM   7268  C  CA    . ARG D 2 35  ? 94.052  78.130  95.478  1.00 35.90  ? 35   ARG B CA    1 
ATOM   7269  C  C     . ARG D 2 35  ? 94.050  78.155  97.019  1.00 36.70  ? 35   ARG B C     1 
ATOM   7270  O  O     . ARG D 2 35  ? 93.374  78.993  97.639  1.00 33.23  ? 35   ARG B O     1 
ATOM   7271  C  CB    . ARG D 2 35  ? 95.050  79.154  94.935  1.00 38.72  ? 35   ARG B CB    1 
ATOM   7272  C  CG    . ARG D 2 35  ? 95.977  78.591  93.900  1.00 48.53  ? 35   ARG B CG    1 
ATOM   7273  C  CD    . ARG D 2 35  ? 96.436  79.660  92.944  1.00 52.41  ? 35   ARG B CD    1 
ATOM   7274  N  NE    . ARG D 2 35  ? 96.762  80.896  93.633  1.00 52.42  ? 35   ARG B NE    1 
ATOM   7275  C  CZ    . ARG D 2 35  ? 96.231  82.070  93.309  1.00 59.59  ? 35   ARG B CZ    1 
ATOM   7276  N  NH1   . ARG D 2 35  ? 95.356  82.130  92.312  1.00 38.39  ? 35   ARG B NH1   1 
ATOM   7277  N  NH2   . ARG D 2 35  ? 96.584  83.177  93.968  1.00 57.25  ? 35   ARG B NH2   1 
ATOM   7278  N  N     . PHE D 2 36  ? 94.804  77.227  97.613  1.00 23.54  ? 36   PHE B N     1 
ATOM   7279  C  CA    . PHE D 2 36  ? 94.950  77.108  99.063  1.00 28.82  ? 36   PHE B CA    1 
ATOM   7280  C  C     . PHE D 2 36  ? 96.404  77.392  99.407  1.00 30.35  ? 36   PHE B C     1 
ATOM   7281  O  O     . PHE D 2 36  ? 97.314  76.649  99.018  1.00 29.03  ? 36   PHE B O     1 
ATOM   7282  C  CB    . PHE D 2 36  ? 94.581  75.703  99.524  1.00 28.47  ? 36   PHE B CB    1 
ATOM   7283  C  CG    . PHE D 2 36  ? 94.895  75.427  100.961 1.00 21.86  ? 36   PHE B CG    1 
ATOM   7284  C  CD1   . PHE D 2 36  ? 95.372  74.183  101.345 1.00 29.00  ? 36   PHE B CD1   1 
ATOM   7285  C  CD2   . PHE D 2 36  ? 94.672  76.377  101.932 1.00 23.41  ? 36   PHE B CD2   1 
ATOM   7286  C  CE1   . PHE D 2 36  ? 95.617  73.895  102.676 1.00 33.84  ? 36   PHE B CE1   1 
ATOM   7287  C  CE2   . PHE D 2 36  ? 94.912  76.096  103.267 1.00 26.46  ? 36   PHE B CE2   1 
ATOM   7288  C  CZ    . PHE D 2 36  ? 95.380  74.857  103.644 1.00 27.64  ? 36   PHE B CZ    1 
ATOM   7289  N  N     . ILE D 2 37  ? 96.586  78.466  100.162 1.00 35.83  ? 37   ILE B N     1 
ATOM   7290  C  CA    . ILE D 2 37  ? 97.880  79.003  100.585 1.00 33.66  ? 37   ILE B CA    1 
ATOM   7291  C  C     . ILE D 2 37  ? 98.258  78.803  102.067 1.00 39.54  ? 37   ILE B C     1 
ATOM   7292  O  O     . ILE D 2 37  ? 97.404  78.851  102.969 1.00 34.69  ? 37   ILE B O     1 
ATOM   7293  C  CB    . ILE D 2 37  ? 97.878  80.524  100.349 1.00 41.07  ? 37   ILE B CB    1 
ATOM   7294  C  CG1   . ILE D 2 37  ? 97.737  80.824  98.876  1.00 44.17  ? 37   ILE B CG1   1 
ATOM   7295  C  CG2   . ILE D 2 37  ? 99.112  81.175  100.911 1.00 41.78  ? 37   ILE B CG2   1 
ATOM   7296  C  CD1   . ILE D 2 37  ? 97.443  82.311  98.668  1.00 52.37  ? 37   ILE B CD1   1 
ATOM   7297  N  N     . VAL D 2 38  ? 99.555  78.616  102.303 1.00 34.25  ? 38   VAL B N     1 
ATOM   7298  C  CA    . VAL D 2 38  ? 100.077 78.509  103.647 1.00 27.12  ? 38   VAL B CA    1 
ATOM   7299  C  C     . VAL D 2 38  ? 100.994 79.724  103.902 1.00 31.50  ? 38   VAL B C     1 
ATOM   7300  O  O     . VAL D 2 38  ? 101.988 79.948  103.193 1.00 34.02  ? 38   VAL B O     1 
ATOM   7301  C  CB    . VAL D 2 38  ? 100.884 77.232  103.851 1.00 21.63  ? 38   VAL B CB    1 
ATOM   7302  C  CG1   . VAL D 2 38  ? 101.398 77.186  105.289 1.00 30.90  ? 38   VAL B CG1   1 
ATOM   7303  C  CG2   . VAL D 2 38  ? 100.025 76.001  103.590 1.00 26.47  ? 38   VAL B CG2   1 
ATOM   7304  N  N     . ARG D 2 39  ? 100.636 80.524  104.898 1.00 31.51  ? 39   ARG B N     1 
ATOM   7305  C  CA    . ARG D 2 39  ? 101.424 81.700  105.280 1.00 30.94  ? 39   ARG B CA    1 
ATOM   7306  C  C     . ARG D 2 39  ? 101.840 81.444  106.745 1.00 29.88  ? 39   ARG B C     1 
ATOM   7307  O  O     . ARG D 2 39  ? 101.001 81.080  107.567 1.00 34.60  ? 39   ARG B O     1 
ATOM   7308  C  CB    . ARG D 2 39  ? 100.567 82.988  105.181 1.00 15.53  ? 39   ARG B CB    1 
ATOM   7309  C  CG    . ARG D 2 39  ? 101.286 84.232  105.705 1.00 25.02  ? 39   ARG B CG    1 
ATOM   7310  C  CD    . ARG D 2 39  ? 100.321 85.303  106.198 1.00 29.23  ? 39   ARG B CD    1 
ATOM   7311  N  NE    . ARG D 2 39  ? 99.413  85.644  105.125 1.00 43.91  ? 39   ARG B NE    1 
ATOM   7312  C  CZ    . ARG D 2 39  ? 98.128  85.923  105.279 1.00 37.33  ? 39   ARG B CZ    1 
ATOM   7313  N  NH1   . ARG D 2 39  ? 97.573  85.923  106.485 1.00 31.11  ? 39   ARG B NH1   1 
ATOM   7314  N  NH2   . ARG D 2 39  ? 97.394  86.148  104.204 1.00 42.24  ? 39   ARG B NH2   1 
ATOM   7315  N  N     . ILE D 2 40  ? 103.123 81.601  107.058 1.00 28.09  ? 40   ILE B N     1 
ATOM   7316  C  CA    . ILE D 2 40  ? 103.624 81.364  108.409 1.00 31.88  ? 40   ILE B CA    1 
ATOM   7317  C  C     . ILE D 2 40  ? 103.610 82.665  109.162 1.00 30.93  ? 40   ILE B C     1 
ATOM   7318  O  O     . ILE D 2 40  ? 104.304 83.589  108.796 1.00 36.90  ? 40   ILE B O     1 
ATOM   7319  C  CB    . ILE D 2 40  ? 105.071 80.834  108.383 1.00 32.05  ? 40   ILE B CB    1 
ATOM   7320  C  CG1   . ILE D 2 40  ? 105.110 79.525  107.632 1.00 28.22  ? 40   ILE B CG1   1 
ATOM   7321  C  CG2   . ILE D 2 40  ? 105.595 80.611  109.813 1.00 24.47  ? 40   ILE B CG2   1 
ATOM   7322  C  CD1   . ILE D 2 40  ? 104.256 78.455  108.298 1.00 37.06  ? 40   ILE B CD1   1 
ATOM   7323  N  N     . GLU D 2 41  ? 102.827 82.759  110.219 1.00 34.96  ? 41   GLU B N     1 
ATOM   7324  C  CA    . GLU D 2 41  ? 102.785 84.021  110.926 1.00 36.85  ? 41   GLU B CA    1 
ATOM   7325  C  C     . GLU D 2 41  ? 103.713 84.020  112.130 1.00 46.59  ? 41   GLU B C     1 
ATOM   7326  O  O     . GLU D 2 41  ? 103.281 83.838  113.274 1.00 43.17  ? 41   GLU B O     1 
ATOM   7327  C  CB    . GLU D 2 41  ? 101.339 84.372  111.293 1.00 37.39  ? 41   GLU B CB    1 
ATOM   7328  C  CG    . GLU D 2 41  ? 100.490 84.700  110.040 1.00 47.90  ? 41   GLU B CG    1 
ATOM   7329  C  CD    . GLU D 2 41  ? 99.172  85.461  110.319 1.00 63.68  ? 41   GLU B CD    1 
ATOM   7330  O  OE1   . GLU D 2 41  ? 98.504  85.888  109.342 1.00 60.35  ? 41   GLU B OE1   1 
ATOM   7331  O  OE2   . GLU D 2 41  ? 98.800  85.637  111.497 1.00 62.86  ? 41   GLU B OE2   1 
ATOM   7332  N  N     . ASP D 2 42  ? 105.003 84.225  111.836 1.00 47.30  ? 42   ASP B N     1 
ATOM   7333  C  CA    . ASP D 2 42  ? 106.068 84.242  112.838 1.00 52.00  ? 42   ASP B CA    1 
ATOM   7334  C  C     . ASP D 2 42  ? 106.557 85.639  113.183 1.00 57.18  ? 42   ASP B C     1 
ATOM   7335  O  O     . ASP D 2 42  ? 107.768 85.865  113.291 1.00 52.44  ? 42   ASP B O     1 
ATOM   7336  C  CB    . ASP D 2 42  ? 107.259 83.396  112.372 1.00 48.99  ? 42   ASP B CB    1 
ATOM   7337  C  CG    . ASP D 2 42  ? 107.796 83.814  111.000 1.00 52.22  ? 42   ASP B CG    1 
ATOM   7338  O  OD1   . ASP D 2 42  ? 108.741 83.148  110.517 1.00 49.66  ? 42   ASP B OD1   1 
ATOM   7339  O  OD2   . ASP D 2 42  ? 107.285 84.781  110.396 1.00 40.58  ? 42   ASP B OD2   1 
ATOM   7340  N  N     . THR D 2 43  ? 105.603 86.549  113.389 1.00 58.92  ? 43   THR B N     1 
ATOM   7341  C  CA    . THR D 2 43  ? 105.876 87.950  113.712 1.00 65.50  ? 43   THR B CA    1 
ATOM   7342  C  C     . THR D 2 43  ? 106.068 88.260  115.198 1.00 71.58  ? 43   THR B C     1 
ATOM   7343  O  O     . THR D 2 43  ? 106.294 89.419  115.556 1.00 69.65  ? 43   THR B O     1 
ATOM   7344  C  CB    . THR D 2 43  ? 104.747 88.883  113.197 1.00 61.68  ? 43   THR B CB    1 
ATOM   7345  O  OG1   . THR D 2 43  ? 103.520 88.592  113.881 1.00 65.55  ? 43   THR B OG1   1 
ATOM   7346  C  CG2   . THR D 2 43  ? 104.537 88.697  111.719 1.00 67.52  ? 43   THR B CG2   1 
ATOM   7347  N  N     . ASP D 2 44  ? 105.954 87.248  116.059 1.00 76.73  ? 44   ASP B N     1 
ATOM   7348  C  CA    . ASP D 2 44  ? 106.136 87.451  117.496 1.00 77.65  ? 44   ASP B CA    1 
ATOM   7349  C  C     . ASP D 2 44  ? 107.404 86.770  117.973 1.00 73.68  ? 44   ASP B C     1 
ATOM   7350  O  O     . ASP D 2 44  ? 107.405 85.593  118.342 1.00 70.65  ? 44   ASP B O     1 
ATOM   7351  C  CB    . ASP D 2 44  ? 104.944 86.924  118.293 1.00 81.19  ? 44   ASP B CB    1 
ATOM   7352  C  CG    . ASP D 2 44  ? 105.208 86.943  119.782 1.00 86.01  ? 44   ASP B CG    1 
ATOM   7353  O  OD1   . ASP D 2 44  ? 105.735 87.967  120.270 1.00 81.51  ? 44   ASP B OD1   1 
ATOM   7354  O  OD2   . ASP D 2 44  ? 104.894 85.941  120.462 1.00 95.85  ? 44   ASP B OD2   1 
ATOM   7355  N  N     . ARG D 2 45  ? 108.482 87.540  117.966 1.00 72.07  ? 45   ARG B N     1 
ATOM   7356  C  CA    . ARG D 2 45  ? 109.790 87.048  118.365 1.00 72.77  ? 45   ARG B CA    1 
ATOM   7357  C  C     . ARG D 2 45  ? 109.818 86.326  119.691 1.00 72.71  ? 45   ARG B C     1 
ATOM   7358  O  O     . ARG D 2 45  ? 110.560 85.372  119.867 1.00 68.94  ? 45   ARG B O     1 
ATOM   7359  C  CB    . ARG D 2 45  ? 110.790 88.190  118.465 1.00 75.02  ? 45   ARG B CB    1 
ATOM   7360  C  CG    . ARG D 2 45  ? 111.062 88.934  117.184 1.00 85.78  ? 45   ARG B CG    1 
ATOM   7361  C  CD    . ARG D 2 45  ? 112.233 89.892  117.412 1.00 95.53  ? 45   ARG B CD    1 
ATOM   7362  N  NE    . ARG D 2 45  ? 112.034 90.746  118.587 1.00 96.71  ? 45   ARG B NE    1 
ATOM   7363  C  CZ    . ARG D 2 45  ? 112.922 91.634  119.031 1.00 96.80  ? 45   ARG B CZ    1 
ATOM   7364  N  NH1   . ARG D 2 45  ? 114.081 91.792  118.401 1.00 93.02  ? 45   ARG B NH1   1 
ATOM   7365  N  NH2   . ARG D 2 45  ? 112.652 92.370  120.105 1.00 91.60  ? 45   ARG B NH2   1 
ATOM   7366  N  N     . ALA D 2 46  ? 109.018 86.803  120.634 1.00 82.09  ? 46   ALA B N     1 
ATOM   7367  C  CA    . ALA D 2 46  ? 108.972 86.225  121.970 1.00 85.71  ? 46   ALA B CA    1 
ATOM   7368  C  C     . ALA D 2 46  ? 108.566 84.756  122.023 1.00 87.71  ? 46   ALA B C     1 
ATOM   7369  O  O     . ALA D 2 46  ? 109.316 83.918  122.527 1.00 88.93  ? 46   ALA B O     1 
ATOM   7370  C  CB    . ALA D 2 46  ? 108.034 87.050  122.849 1.00 85.61  ? 46   ALA B CB    1 
ATOM   7371  N  N     . ARG D 2 47  ? 107.379 84.448  121.510 1.00 87.45  ? 47   ARG B N     1 
ATOM   7372  C  CA    . ARG D 2 47  ? 106.867 83.081  121.537 1.00 87.80  ? 47   ARG B CA    1 
ATOM   7373  C  C     . ARG D 2 47  ? 107.313 82.229  120.354 1.00 84.20  ? 47   ARG B C     1 
ATOM   7374  O  O     . ARG D 2 47  ? 106.979 81.047  120.272 1.00 84.63  ? 47   ARG B O     1 
ATOM   7375  C  CB    . ARG D 2 47  ? 105.336 83.096  121.590 1.00 92.86  ? 47   ARG B CB    1 
ATOM   7376  C  CG    . ARG D 2 47  ? 104.733 83.950  122.708 1.00 97.41  ? 47   ARG B CG    1 
ATOM   7377  C  CD    . ARG D 2 47  ? 103.227 83.732  122.780 1.00 94.85  ? 47   ARG B CD    1 
ATOM   7378  N  NE    . ARG D 2 47  ? 102.630 83.788  121.448 1.00 96.90  ? 47   ARG B NE    1 
ATOM   7379  C  CZ    . ARG D 2 47  ? 101.397 83.386  121.158 1.00 95.97  ? 47   ARG B CZ    1 
ATOM   7380  N  NH1   . ARG D 2 47  ? 100.612 82.895  122.105 1.00 95.51  ? 47   ARG B NH1   1 
ATOM   7381  N  NH2   . ARG D 2 47  ? 100.953 83.460  119.912 1.00 97.52  ? 47   ARG B NH2   1 
ATOM   7382  N  N     . TYR D 2 48  ? 108.071 82.828  119.446 1.00 81.40  ? 48   TYR B N     1 
ATOM   7383  C  CA    . TYR D 2 48  ? 108.544 82.124  118.262 1.00 79.35  ? 48   TYR B CA    1 
ATOM   7384  C  C     . TYR D 2 48  ? 109.403 80.898  118.567 1.00 77.91  ? 48   TYR B C     1 
ATOM   7385  O  O     . TYR D 2 48  ? 110.387 80.982  119.309 1.00 71.20  ? 48   TYR B O     1 
ATOM   7386  C  CB    . TYR D 2 48  ? 109.315 83.099  117.363 1.00 80.22  ? 48   TYR B CB    1 
ATOM   7387  C  CG    . TYR D 2 48  ? 110.161 82.418  116.319 1.00 80.51  ? 48   TYR B CG    1 
ATOM   7388  C  CD1   . TYR D 2 48  ? 111.545 82.304  116.484 1.00 75.67  ? 48   TYR B CD1   1 
ATOM   7389  C  CD2   . TYR D 2 48  ? 109.572 81.825  115.198 1.00 77.37  ? 48   TYR B CD2   1 
ATOM   7390  C  CE1   . TYR D 2 48  ? 112.323 81.609  115.565 1.00 79.12  ? 48   TYR B CE1   1 
ATOM   7391  C  CE2   . TYR D 2 48  ? 110.342 81.125  114.267 1.00 81.68  ? 48   TYR B CE2   1 
ATOM   7392  C  CZ    . TYR D 2 48  ? 111.719 81.017  114.459 1.00 85.30  ? 48   TYR B CZ    1 
ATOM   7393  O  OH    . TYR D 2 48  ? 112.490 80.295  113.567 1.00 85.69  ? 48   TYR B OH    1 
ATOM   7394  N  N     . VAL D 2 49  ? 109.018 79.762  117.990 1.00 76.63  ? 49   VAL B N     1 
ATOM   7395  C  CA    . VAL D 2 49  ? 109.751 78.517  118.170 1.00 80.01  ? 49   VAL B CA    1 
ATOM   7396  C  C     . VAL D 2 49  ? 110.300 78.073  116.817 1.00 84.39  ? 49   VAL B C     1 
ATOM   7397  O  O     . VAL D 2 49  ? 109.561 77.550  115.982 1.00 84.96  ? 49   VAL B O     1 
ATOM   7398  C  CB    . VAL D 2 49  ? 108.848 77.402  118.708 1.00 80.99  ? 49   VAL B CB    1 
ATOM   7399  C  CG1   . VAL D 2 49  ? 109.694 76.170  119.038 1.00 80.54  ? 49   VAL B CG1   1 
ATOM   7400  C  CG2   . VAL D 2 49  ? 108.083 77.895  119.925 1.00 78.35  ? 49   VAL B CG2   1 
ATOM   7401  N  N     . PRO D 2 50  ? 111.607 78.283  116.572 1.00 86.39  ? 50   PRO B N     1 
ATOM   7402  C  CA    . PRO D 2 50  ? 112.120 77.853  115.268 1.00 84.68  ? 50   PRO B CA    1 
ATOM   7403  C  C     . PRO D 2 50  ? 111.852 76.366  115.018 1.00 83.82  ? 50   PRO B C     1 
ATOM   7404  O  O     . PRO D 2 50  ? 111.937 75.546  115.937 1.00 87.23  ? 50   PRO B O     1 
ATOM   7405  C  CB    . PRO D 2 50  ? 113.611 78.207  115.345 1.00 83.51  ? 50   PRO B CB    1 
ATOM   7406  C  CG    . PRO D 2 50  ? 113.910 78.122  116.814 1.00 86.37  ? 50   PRO B CG    1 
ATOM   7407  C  CD    . PRO D 2 50  ? 112.696 78.791  117.425 1.00 87.99  ? 50   PRO B CD    1 
ATOM   7408  N  N     . GLY D 2 51  ? 111.497 76.030  113.780 1.00 73.88  ? 51   GLY B N     1 
ATOM   7409  C  CA    . GLY D 2 51  ? 111.217 74.646  113.449 1.00 68.41  ? 51   GLY B CA    1 
ATOM   7410  C  C     . GLY D 2 51  ? 109.755 74.267  113.591 1.00 65.02  ? 51   GLY B C     1 
ATOM   7411  O  O     . GLY D 2 51  ? 109.314 73.263  113.041 1.00 62.24  ? 51   GLY B O     1 
ATOM   7412  N  N     . ALA D 2 52  ? 108.991 75.049  114.341 1.00 62.36  ? 52   ALA B N     1 
ATOM   7413  C  CA    . ALA D 2 52  ? 107.576 74.738  114.494 1.00 60.03  ? 52   ALA B CA    1 
ATOM   7414  C  C     . ALA D 2 52  ? 106.997 74.732  113.078 1.00 58.27  ? 52   ALA B C     1 
ATOM   7415  O  O     . ALA D 2 52  ? 106.006 74.045  112.782 1.00 49.34  ? 52   ALA B O     1 
ATOM   7416  C  CB    . ALA D 2 52  ? 106.875 75.798  115.367 1.00 49.77  ? 52   ALA B CB    1 
ATOM   7417  N  N     . GLU D 2 53  ? 107.668 75.464  112.197 1.00 50.91  ? 53   GLU B N     1 
ATOM   7418  C  CA    . GLU D 2 53  ? 107.233 75.564  110.821 1.00 49.96  ? 53   GLU B CA    1 
ATOM   7419  C  C     . GLU D 2 53  ? 107.338 74.239  110.079 1.00 46.41  ? 53   GLU B C     1 
ATOM   7420  O  O     . GLU D 2 53  ? 106.345 73.733  109.552 1.00 41.86  ? 53   GLU B O     1 
ATOM   7421  C  CB    . GLU D 2 53  ? 108.051 76.632  110.108 1.00 55.67  ? 53   GLU B CB    1 
ATOM   7422  C  CG    . GLU D 2 53  ? 107.816 76.725  108.625 1.00 57.43  ? 53   GLU B CG    1 
ATOM   7423  C  CD    . GLU D 2 53  ? 108.654 77.824  107.993 1.00 68.86  ? 53   GLU B CD    1 
ATOM   7424  O  OE1   . GLU D 2 53  ? 108.635 77.938  106.751 1.00 69.97  ? 53   GLU B OE1   1 
ATOM   7425  O  OE2   . GLU D 2 53  ? 109.330 78.574  108.740 1.00 67.11  ? 53   GLU B OE2   1 
ATOM   7426  N  N     . GLU D 2 54  ? 108.542 73.680  110.040 1.00 45.34  ? 54   GLU B N     1 
ATOM   7427  C  CA    . GLU D 2 54  ? 108.770 72.425  109.338 1.00 48.73  ? 54   GLU B CA    1 
ATOM   7428  C  C     . GLU D 2 54  ? 107.828 71.339  109.829 1.00 48.88  ? 54   GLU B C     1 
ATOM   7429  O  O     . GLU D 2 54  ? 107.325 70.542  109.029 1.00 48.01  ? 54   GLU B O     1 
ATOM   7430  C  CB    . GLU D 2 54  ? 110.237 71.973  109.490 1.00 60.92  ? 54   GLU B CB    1 
ATOM   7431  C  CG    . GLU D 2 54  ? 110.671 71.632  110.939 1.00 86.63  ? 54   GLU B CG    1 
ATOM   7432  C  CD    . GLU D 2 54  ? 112.200 71.678  111.177 1.00 97.37  ? 54   GLU B CD    1 
ATOM   7433  O  OE1   . GLU D 2 54  ? 112.641 71.302  112.296 1.00 93.84  ? 54   GLU B OE1   1 
ATOM   7434  O  OE2   . GLU D 2 54  ? 112.952 72.097  110.259 1.00 99.97  ? 54   GLU B OE2   1 
ATOM   7435  N  N     . ARG D 2 55  ? 107.562 71.330  111.135 1.00 44.26  ? 55   ARG B N     1 
ATOM   7436  C  CA    . ARG D 2 55  ? 106.694 70.320  111.726 1.00 40.03  ? 55   ARG B CA    1 
ATOM   7437  C  C     . ARG D 2 55  ? 105.226 70.524  111.355 1.00 43.83  ? 55   ARG B C     1 
ATOM   7438  O  O     . ARG D 2 55  ? 104.505 69.557  111.068 1.00 44.79  ? 55   ARG B O     1 
ATOM   7439  C  CB    . ARG D 2 55  ? 106.885 70.292  113.245 1.00 36.68  ? 55   ARG B CB    1 
ATOM   7440  C  CG    . ARG D 2 55  ? 108.296 69.841  113.645 1.00 42.20  ? 55   ARG B CG    1 
ATOM   7441  C  CD    . ARG D 2 55  ? 108.552 70.037  115.123 1.00 38.79  ? 55   ARG B CD    1 
ATOM   7442  N  NE    . ARG D 2 55  ? 107.657 69.207  115.918 1.00 49.07  ? 55   ARG B NE    1 
ATOM   7443  C  CZ    . ARG D 2 55  ? 107.244 69.510  117.145 1.00 46.47  ? 55   ARG B CZ    1 
ATOM   7444  N  NH1   . ARG D 2 55  ? 107.644 70.636  117.724 1.00 48.86  ? 55   ARG B NH1   1 
ATOM   7445  N  NH2   . ARG D 2 55  ? 106.434 68.682  117.791 1.00 39.04  ? 55   ARG B NH2   1 
ATOM   7446  N  N     . ILE D 2 56  ? 104.760 71.765  111.335 1.00 39.91  ? 56   ILE B N     1 
ATOM   7447  C  CA    . ILE D 2 56  ? 103.378 71.938  110.956 1.00 37.26  ? 56   ILE B CA    1 
ATOM   7448  C  C     . ILE D 2 56  ? 103.165 71.678  109.437 1.00 34.42  ? 56   ILE B C     1 
ATOM   7449  O  O     . ILE D 2 56  ? 102.130 71.142  109.030 1.00 25.75  ? 56   ILE B O     1 
ATOM   7450  C  CB    . ILE D 2 56  ? 102.823 73.302  111.433 1.00 35.88  ? 56   ILE B CB    1 
ATOM   7451  C  CG1   . ILE D 2 56  ? 101.412 73.475  110.887 1.00 46.61  ? 56   ILE B CG1   1 
ATOM   7452  C  CG2   . ILE D 2 56  ? 103.714 74.416  111.037 1.00 42.82  ? 56   ILE B CG2   1 
ATOM   7453  C  CD1   . ILE D 2 56  ? 100.538 72.266  111.215 1.00 28.44  ? 56   ILE B CD1   1 
ATOM   7454  N  N     . LEU D 2 57  ? 104.145 71.987  108.595 1.00 30.61  ? 57   LEU B N     1 
ATOM   7455  C  CA    . LEU D 2 57  ? 103.945 71.690  107.169 1.00 38.41  ? 57   LEU B CA    1 
ATOM   7456  C  C     . LEU D 2 57  ? 103.952 70.177  106.954 1.00 38.73  ? 57   LEU B C     1 
ATOM   7457  O  O     . LEU D 2 57  ? 103.220 69.645  106.097 1.00 38.23  ? 57   LEU B O     1 
ATOM   7458  C  CB    . LEU D 2 57  ? 105.030 72.325  106.291 1.00 27.87  ? 57   LEU B CB    1 
ATOM   7459  C  CG    . LEU D 2 57  ? 105.099 73.849  106.369 1.00 35.79  ? 57   LEU B CG    1 
ATOM   7460  C  CD1   . LEU D 2 57  ? 106.317 74.304  105.603 1.00 32.01  ? 57   LEU B CD1   1 
ATOM   7461  C  CD2   . LEU D 2 57  ? 103.833 74.483  105.823 1.00 25.78  ? 57   LEU B CD2   1 
ATOM   7462  N  N     . ALA D 2 58  ? 104.788 69.494  107.735 1.00 32.04  ? 58   ALA B N     1 
ATOM   7463  C  CA    . ALA D 2 58  ? 104.911 68.039  107.656 1.00 32.87  ? 58   ALA B CA    1 
ATOM   7464  C  C     . ALA D 2 58  ? 103.605 67.385  108.106 1.00 34.51  ? 58   ALA B C     1 
ATOM   7465  O  O     . ALA D 2 58  ? 103.143 66.403  107.502 1.00 30.26  ? 58   ALA B O     1 
ATOM   7466  C  CB    . ALA D 2 58  ? 106.074 67.555  108.539 1.00 27.61  ? 58   ALA B CB    1 
ATOM   7467  N  N     . ALA D 2 59  ? 103.019 67.931  109.172 1.00 35.39  ? 59   ALA B N     1 
ATOM   7468  C  CA    . ALA D 2 59  ? 101.761 67.408  109.700 1.00 35.14  ? 59   ALA B CA    1 
ATOM   7469  C  C     . ALA D 2 59  ? 100.617 67.541  108.671 1.00 33.06  ? 59   ALA B C     1 
ATOM   7470  O  O     . ALA D 2 59  ? 99.832  66.612  108.488 1.00 30.88  ? 59   ALA B O     1 
ATOM   7471  C  CB    . ALA D 2 59  ? 101.401 68.122  110.980 1.00 28.49  ? 59   ALA B CB    1 
ATOM   7472  N  N     . LEU D 2 60  ? 100.540 68.670  107.979 1.00 29.04  ? 60   LEU B N     1 
ATOM   7473  C  CA    . LEU D 2 60  ? 99.479  68.869  106.978 1.00 32.65  ? 60   LEU B CA    1 
ATOM   7474  C  C     . LEU D 2 60  ? 99.562  67.873  105.832 1.00 32.13  ? 60   LEU B C     1 
ATOM   7475  O  O     . LEU D 2 60  ? 98.547  67.362  105.363 1.00 34.20  ? 60   LEU B O     1 
ATOM   7476  C  CB    . LEU D 2 60  ? 99.548  70.275  106.390 1.00 34.81  ? 60   LEU B CB    1 
ATOM   7477  C  CG    . LEU D 2 60  ? 99.400  71.392  107.414 1.00 36.18  ? 60   LEU B CG    1 
ATOM   7478  C  CD1   . LEU D 2 60  ? 99.501  72.734  106.702 1.00 37.49  ? 60   LEU B CD1   1 
ATOM   7479  C  CD2   . LEU D 2 60  ? 98.071  71.228  108.151 1.00 42.99  ? 60   LEU B CD2   1 
ATOM   7480  N  N     . LYS D 2 61  ? 100.777 67.607  105.377 1.00 35.54  ? 61   LYS B N     1 
ATOM   7481  C  CA    . LYS D 2 61  ? 100.974 66.665  104.294 1.00 41.80  ? 61   LYS B CA    1 
ATOM   7482  C  C     . LYS D 2 61  ? 100.643 65.251  104.789 1.00 42.07  ? 61   LYS B C     1 
ATOM   7483  O  O     . LYS D 2 61  ? 100.051 64.433  104.060 1.00 39.85  ? 61   LYS B O     1 
ATOM   7484  C  CB    . LYS D 2 61  ? 102.419 66.747  103.802 1.00 46.54  ? 61   LYS B CB    1 
ATOM   7485  C  CG    . LYS D 2 61  ? 102.836 68.172  103.469 1.00 50.26  ? 61   LYS B CG    1 
ATOM   7486  C  CD    . LYS D 2 61  ? 104.235 68.235  102.883 1.00 53.82  ? 61   LYS B CD    1 
ATOM   7487  C  CE    . LYS D 2 61  ? 104.583 69.657  102.481 1.00 54.20  ? 61   LYS B CE    1 
ATOM   7488  N  NZ    . LYS D 2 61  ? 105.834 69.682  101.684 1.00 64.33  ? 61   LYS B NZ    1 
ATOM   7489  N  N     . TRP D 2 62  ? 101.010 64.973  106.039 1.00 34.73  ? 62   TRP B N     1 
ATOM   7490  C  CA    . TRP D 2 62  ? 100.735 63.662  106.635 1.00 28.26  ? 62   TRP B CA    1 
ATOM   7491  C  C     . TRP D 2 62  ? 99.230  63.417  106.671 1.00 32.06  ? 62   TRP B C     1 
ATOM   7492  O  O     . TRP D 2 62  ? 98.776  62.299  106.469 1.00 34.06  ? 62   TRP B O     1 
ATOM   7493  C  CB    . TRP D 2 62  ? 101.267 63.605  108.059 1.00 21.77  ? 62   TRP B CB    1 
ATOM   7494  C  CG    . TRP D 2 62  ? 100.959 62.333  108.771 1.00 31.63  ? 62   TRP B CG    1 
ATOM   7495  C  CD1   . TRP D 2 62  ? 101.500 61.097  108.525 1.00 28.42  ? 62   TRP B CD1   1 
ATOM   7496  C  CD2   . TRP D 2 62  ? 100.100 62.172  109.901 1.00 30.50  ? 62   TRP B CD2   1 
ATOM   7497  N  NE1   . TRP D 2 62  ? 101.040 60.194  109.437 1.00 26.99  ? 62   TRP B NE1   1 
ATOM   7498  C  CE2   . TRP D 2 62  ? 100.181 60.818  110.295 1.00 25.54  ? 62   TRP B CE2   1 
ATOM   7499  C  CE3   . TRP D 2 62  ? 99.276  63.043  110.625 1.00 24.27  ? 62   TRP B CE3   1 
ATOM   7500  C  CZ2   . TRP D 2 62  ? 99.471  60.307  111.383 1.00 32.71  ? 62   TRP B CZ2   1 
ATOM   7501  C  CZ3   . TRP D 2 62  ? 98.572  62.538  111.706 1.00 29.18  ? 62   TRP B CZ3   1 
ATOM   7502  C  CH2   . TRP D 2 62  ? 98.673  61.177  112.078 1.00 29.09  ? 62   TRP B CH2   1 
ATOM   7503  N  N     . LEU D 2 63  ? 98.464  64.478  106.921 1.00 33.53  ? 63   LEU B N     1 
ATOM   7504  C  CA    . LEU D 2 63  ? 97.019  64.377  106.993 1.00 31.23  ? 63   LEU B CA    1 
ATOM   7505  C  C     . LEU D 2 63  ? 96.411  64.161  105.648 1.00 33.27  ? 63   LEU B C     1 
ATOM   7506  O  O     . LEU D 2 63  ? 95.264  63.733  105.552 1.00 45.79  ? 63   LEU B O     1 
ATOM   7507  C  CB    . LEU D 2 63  ? 96.426  65.615  107.652 1.00 33.07  ? 63   LEU B CB    1 
ATOM   7508  C  CG    . LEU D 2 63  ? 96.241  65.424  109.166 1.00 42.64  ? 63   LEU B CG    1 
ATOM   7509  C  CD1   . LEU D 2 63  ? 96.169  66.763  109.864 1.00 44.40  ? 63   LEU B CD1   1 
ATOM   7510  C  CD2   . LEU D 2 63  ? 94.983  64.630  109.422 1.00 34.79  ? 63   LEU B CD2   1 
ATOM   7511  N  N     . GLY D 2 64  ? 97.186  64.421  104.601 1.00 34.01  ? 64   GLY B N     1 
ATOM   7512  C  CA    . GLY D 2 64  ? 96.678  64.227  103.258 1.00 29.95  ? 64   GLY B CA    1 
ATOM   7513  C  C     . GLY D 2 64  ? 96.352  65.518  102.521 1.00 35.16  ? 64   GLY B C     1 
ATOM   7514  O  O     . GLY D 2 64  ? 95.781  65.493  101.435 1.00 38.11  ? 64   GLY B O     1 
ATOM   7515  N  N     . LEU D 2 65  ? 96.731  66.653  103.083 1.00 28.06  ? 65   LEU B N     1 
ATOM   7516  C  CA    . LEU D 2 65  ? 96.444  67.915  102.424 1.00 38.19  ? 65   LEU B CA    1 
ATOM   7517  C  C     . LEU D 2 65  ? 97.606  68.306  101.539 1.00 41.25  ? 65   LEU B C     1 
ATOM   7518  O  O     . LEU D 2 65  ? 98.710  67.777  101.669 1.00 54.07  ? 65   LEU B O     1 
ATOM   7519  C  CB    . LEU D 2 65  ? 96.174  69.002  103.472 1.00 30.45  ? 65   LEU B CB    1 
ATOM   7520  C  CG    . LEU D 2 65  ? 95.112  68.499  104.453 1.00 33.81  ? 65   LEU B CG    1 
ATOM   7521  C  CD1   . LEU D 2 65  ? 95.030  69.424  105.625 1.00 33.75  ? 65   LEU B CD1   1 
ATOM   7522  C  CD2   . LEU D 2 65  ? 93.772  68.341  103.732 1.00 22.71  ? 65   LEU B CD2   1 
ATOM   7523  N  N     . SER D 2 66  ? 97.330  69.201  100.605 1.00 43.14  ? 66   SER B N     1 
ATOM   7524  C  CA    . SER D 2 66  ? 98.330  69.725  99.694  1.00 36.79  ? 66   SER B CA    1 
ATOM   7525  C  C     . SER D 2 66  ? 98.016  71.194  99.663  1.00 32.41  ? 66   SER B C     1 
ATOM   7526  O  O     . SER D 2 66  ? 96.880  71.584  99.889  1.00 39.30  ? 66   SER B O     1 
ATOM   7527  C  CB    . SER D 2 66  ? 98.143  69.144  98.303  1.00 41.73  ? 66   SER B CB    1 
ATOM   7528  O  OG    . SER D 2 66  ? 98.513  67.779  98.304  1.00 58.98  ? 66   SER B OG    1 
ATOM   7529  N  N     . TYR D 2 67  ? 99.007  72.025  99.441  1.00 22.93  ? 67   TYR B N     1 
ATOM   7530  C  CA    . TYR D 2 67  ? 98.706  73.425  99.360  1.00 30.77  ? 67   TYR B CA    1 
ATOM   7531  C  C     . TYR D 2 67  ? 99.315  73.903  98.056  1.00 32.74  ? 67   TYR B C     1 
ATOM   7532  O  O     . TYR D 2 67  ? 100.201 73.265  97.518  1.00 37.01  ? 67   TYR B O     1 
ATOM   7533  C  CB    . TYR D 2 67  ? 99.225  74.183  100.582 1.00 30.75  ? 67   TYR B CB    1 
ATOM   7534  C  CG    . TYR D 2 67  ? 100.546 73.736  101.126 1.00 30.68  ? 67   TYR B CG    1 
ATOM   7535  C  CD1   . TYR D 2 67  ? 100.625 72.707  102.047 1.00 32.14  ? 67   TYR B CD1   1 
ATOM   7536  C  CD2   . TYR D 2 67  ? 101.729 74.368  100.736 1.00 34.83  ? 67   TYR B CD2   1 
ATOM   7537  C  CE1   . TYR D 2 67  ? 101.852 72.311  102.575 1.00 31.82  ? 67   TYR B CE1   1 
ATOM   7538  C  CE2   . TYR D 2 67  ? 102.963 73.979  101.259 1.00 34.48  ? 67   TYR B CE2   1 
ATOM   7539  C  CZ    . TYR D 2 67  ? 103.015 72.951  102.171 1.00 28.61  ? 67   TYR B CZ    1 
ATOM   7540  O  OH    . TYR D 2 67  ? 104.235 72.537  102.634 1.00 39.61  ? 67   TYR B OH    1 
ATOM   7541  N  N     . ASP D 2 68  ? 98.824  75.007  97.530  1.00 33.36  ? 68   ASP B N     1 
ATOM   7542  C  CA    . ASP D 2 68  ? 99.315  75.487  96.258  1.00 32.42  ? 68   ASP B CA    1 
ATOM   7543  C  C     . ASP D 2 68  ? 100.434 76.534  96.332  1.00 39.31  ? 68   ASP B C     1 
ATOM   7544  O  O     . ASP D 2 68  ? 101.162 76.738  95.360  1.00 35.38  ? 68   ASP B O     1 
ATOM   7545  C  CB    . ASP D 2 68  ? 98.119  76.008  95.485  1.00 26.36  ? 68   ASP B CB    1 
ATOM   7546  C  CG    . ASP D 2 68  ? 97.004  74.987  95.416  1.00 29.50  ? 68   ASP B CG    1 
ATOM   7547  O  OD1   . ASP D 2 68  ? 95.847  75.327  95.726  1.00 42.00  ? 68   ASP B OD1   1 
ATOM   7548  O  OD2   . ASP D 2 68  ? 97.279  73.831  95.056  1.00 29.73  ? 68   ASP B OD2   1 
ATOM   7549  N  N     . GLU D 2 69  ? 100.558 77.201  97.475  1.00 31.59  ? 69   GLU B N     1 
ATOM   7550  C  CA    . GLU D 2 69  ? 101.589 78.216  97.672  1.00 24.24  ? 69   GLU B CA    1 
ATOM   7551  C  C     . GLU D 2 69  ? 101.975 78.114  99.119  1.00 28.33  ? 69   GLU B C     1 
ATOM   7552  O  O     . GLU D 2 69  ? 101.160 77.709  99.951  1.00 35.31  ? 69   GLU B O     1 
ATOM   7553  C  CB    . GLU D 2 69  ? 101.052 79.620  97.394  1.00 31.50  ? 69   GLU B CB    1 
ATOM   7554  C  CG    . GLU D 2 69  ? 100.634 79.846  95.964  1.00 31.54  ? 69   GLU B CG    1 
ATOM   7555  C  CD    . GLU D 2 69  ? 100.018 81.202  95.770  1.00 37.91  ? 69   GLU B CD    1 
ATOM   7556  O  OE1   . GLU D 2 69  ? 100.456 82.163  96.433  1.00 46.92  ? 69   GLU B OE1   1 
ATOM   7557  O  OE2   . GLU D 2 69  ? 99.096  81.321  94.943  1.00 52.27  ? 69   GLU B OE2   1 
ATOM   7558  N  N     . GLY D 2 70  ? 103.208 78.486  99.429  1.00 28.89  ? 70   GLY B N     1 
ATOM   7559  C  CA    . GLY D 2 70  ? 103.669 78.390  100.792 1.00 27.17  ? 70   GLY B CA    1 
ATOM   7560  C  C     . GLY D 2 70  ? 105.172 78.560  100.826 1.00 35.28  ? 70   GLY B C     1 
ATOM   7561  O  O     . GLY D 2 70  ? 105.816 78.577  99.789  1.00 33.20  ? 70   GLY B O     1 
ATOM   7562  N  N     . PRO D 2 71  ? 105.757 78.643  102.023 1.00 39.97  ? 71   PRO B N     1 
ATOM   7563  C  CA    . PRO D 2 71  ? 107.190 78.824  102.264 1.00 33.85  ? 71   PRO B CA    1 
ATOM   7564  C  C     . PRO D 2 71  ? 108.083 77.837  101.544 1.00 39.29  ? 71   PRO B C     1 
ATOM   7565  O  O     . PRO D 2 71  ? 109.031 78.233  100.870 1.00 51.35  ? 71   PRO B O     1 
ATOM   7566  C  CB    . PRO D 2 71  ? 107.321 78.677  103.780 1.00 32.26  ? 71   PRO B CB    1 
ATOM   7567  C  CG    . PRO D 2 71  ? 105.914 78.914  104.300 1.00 44.25  ? 71   PRO B CG    1 
ATOM   7568  C  CD    . PRO D 2 71  ? 105.068 78.245  103.263 1.00 34.88  ? 71   PRO B CD    1 
ATOM   7569  N  N     . ASP D 2 72  ? 107.794 76.553  101.682 1.00 40.01  ? 72   ASP B N     1 
ATOM   7570  C  CA    . ASP D 2 72  ? 108.637 75.548  101.050 1.00 51.29  ? 72   ASP B CA    1 
ATOM   7571  C  C     . ASP D 2 72  ? 108.305 75.188  99.608  1.00 54.73  ? 72   ASP B C     1 
ATOM   7572  O  O     . ASP D 2 72  ? 108.981 74.354  99.017  1.00 66.46  ? 72   ASP B O     1 
ATOM   7573  C  CB    . ASP D 2 72  ? 108.679 74.283  101.926 1.00 41.61  ? 72   ASP B CB    1 
ATOM   7574  C  CG    . ASP D 2 72  ? 107.310 73.642  102.124 1.00 45.91  ? 72   ASP B CG    1 
ATOM   7575  O  OD1   . ASP D 2 72  ? 106.262 74.289  101.866 1.00 42.59  ? 72   ASP B OD1   1 
ATOM   7576  O  OD2   . ASP D 2 72  ? 107.290 72.474  102.561 1.00 39.53  ? 72   ASP B OD2   1 
ATOM   7577  N  N     . VAL D 2 73  ? 107.289 75.825  99.032  1.00 55.02  ? 73   VAL B N     1 
ATOM   7578  C  CA    . VAL D 2 73  ? 106.901 75.529  97.660  1.00 48.75  ? 73   VAL B CA    1 
ATOM   7579  C  C     . VAL D 2 73  ? 106.915 76.800  96.827  1.00 40.62  ? 73   VAL B C     1 
ATOM   7580  O  O     . VAL D 2 73  ? 106.637 76.770  95.640  1.00 44.75  ? 73   VAL B O     1 
ATOM   7581  C  CB    . VAL D 2 73  ? 105.480 74.904  97.621  1.00 58.98  ? 73   VAL B CB    1 
ATOM   7582  C  CG1   . VAL D 2 73  ? 105.048 74.633  96.187  1.00 58.28  ? 73   VAL B CG1   1 
ATOM   7583  C  CG2   . VAL D 2 73  ? 105.467 73.603  98.419  1.00 61.64  ? 73   VAL B CG2   1 
ATOM   7584  N  N     . GLY D 2 74  ? 107.245 77.926  97.449  1.00 41.93  ? 74   GLY B N     1 
ATOM   7585  C  CA    . GLY D 2 74  ? 107.248 79.184  96.720  1.00 34.65  ? 74   GLY B CA    1 
ATOM   7586  C  C     . GLY D 2 74  ? 105.864 79.552  96.182  1.00 32.88  ? 74   GLY B C     1 
ATOM   7587  O  O     . GLY D 2 74  ? 104.868 78.934  96.535  1.00 34.79  ? 74   GLY B O     1 
ATOM   7588  N  N     . GLY D 2 75  ? 105.800 80.563  95.323  1.00 34.04  ? 75   GLY B N     1 
ATOM   7589  C  CA    . GLY D 2 75  ? 104.538 80.996  94.769  1.00 25.89  ? 75   GLY B CA    1 
ATOM   7590  C  C     . GLY D 2 75  ? 104.740 82.411  94.289  1.00 37.72  ? 75   GLY B C     1 
ATOM   7591  O  O     . GLY D 2 75  ? 105.755 83.026  94.613  1.00 37.80  ? 75   GLY B O     1 
ATOM   7592  N  N     . PRO D 2 76  ? 103.778 82.968  93.541  1.00 40.07  ? 76   PRO B N     1 
ATOM   7593  C  CA    . PRO D 2 76  ? 103.810 84.328  92.980  1.00 40.08  ? 76   PRO B CA    1 
ATOM   7594  C  C     . PRO D 2 76  ? 103.720 85.488  93.957  1.00 47.50  ? 76   PRO B C     1 
ATOM   7595  O  O     . PRO D 2 76  ? 103.945 86.647  93.567  1.00 43.90  ? 76   PRO B O     1 
ATOM   7596  C  CB    . PRO D 2 76  ? 102.612 84.357  92.014  1.00 38.22  ? 76   PRO B CB    1 
ATOM   7597  C  CG    . PRO D 2 76  ? 102.101 82.921  91.958  1.00 42.86  ? 76   PRO B CG    1 
ATOM   7598  C  CD    . PRO D 2 76  ? 102.495 82.302  93.262  1.00 32.28  ? 76   PRO B CD    1 
ATOM   7599  N  N     . HIS D 2 77  ? 103.379 85.211  95.211  1.00 48.43  ? 77   HIS B N     1 
ATOM   7600  C  CA    . HIS D 2 77  ? 103.238 86.314  96.162  1.00 45.17  ? 77   HIS B CA    1 
ATOM   7601  C  C     . HIS D 2 77  ? 104.016 86.170  97.453  1.00 38.83  ? 77   HIS B C     1 
ATOM   7602  O  O     . HIS D 2 77  ? 103.553 86.618  98.495  1.00 42.08  ? 77   HIS B O     1 
ATOM   7603  C  CB    . HIS D 2 77  ? 101.764 86.516  96.507  1.00 49.04  ? 77   HIS B CB    1 
ATOM   7604  C  CG    . HIS D 2 77  ? 100.842 86.398  95.334  1.00 57.71  ? 77   HIS B CG    1 
ATOM   7605  N  ND1   . HIS D 2 77  ? 100.840 87.300  94.292  1.00 53.66  ? 77   HIS B ND1   1 
ATOM   7606  C  CD2   . HIS D 2 77  ? 99.869  85.495  95.055  1.00 65.43  ? 77   HIS B CD2   1 
ATOM   7607  C  CE1   . HIS D 2 77  ? 99.902  86.961  93.424  1.00 60.58  ? 77   HIS B CE1   1 
ATOM   7608  N  NE2   . HIS D 2 77  ? 99.298  85.871  93.864  1.00 61.85  ? 77   HIS B NE2   1 
ATOM   7609  N  N     . GLY D 2 78  ? 105.186 85.545  97.398  1.00 33.10  ? 78   GLY B N     1 
ATOM   7610  C  CA    . GLY D 2 78  ? 105.968 85.392  98.615  1.00 30.58  ? 78   GLY B CA    1 
ATOM   7611  C  C     . GLY D 2 78  ? 106.604 86.690  99.038  1.00 25.91  ? 78   GLY B C     1 
ATOM   7612  O  O     . GLY D 2 78  ? 106.376 87.706  98.406  1.00 28.25  ? 78   GLY B O     1 
ATOM   7613  N  N     . PRO D 2 79  ? 107.364 86.710  100.138 1.00 31.46  ? 79   PRO B N     1 
ATOM   7614  C  CA    . PRO D 2 79  ? 107.672 85.598  101.047 1.00 29.32  ? 79   PRO B CA    1 
ATOM   7615  C  C     . PRO D 2 79  ? 106.379 85.116  101.703 1.00 35.30  ? 79   PRO B C     1 
ATOM   7616  O  O     . PRO D 2 79  ? 105.402 85.873  101.809 1.00 37.51  ? 79   PRO B O     1 
ATOM   7617  C  CB    . PRO D 2 79  ? 108.576 86.239  102.113 1.00 19.14  ? 79   PRO B CB    1 
ATOM   7618  C  CG    . PRO D 2 79  ? 109.081 87.443  101.500 1.00 23.73  ? 79   PRO B CG    1 
ATOM   7619  C  CD    . PRO D 2 79  ? 107.980 87.954  100.613 1.00 18.44  ? 79   PRO B CD    1 
ATOM   7620  N  N     . TYR D 2 80  ? 106.398 83.880  102.177 1.00 34.05  ? 80   TYR B N     1 
ATOM   7621  C  CA    . TYR D 2 80  ? 105.253 83.286  102.858 1.00 35.37  ? 80   TYR B CA    1 
ATOM   7622  C  C     . TYR D 2 80  ? 105.529 83.127  104.364 1.00 33.58  ? 80   TYR B C     1 
ATOM   7623  O  O     . TYR D 2 80  ? 104.960 82.283  105.037 1.00 38.00  ? 80   TYR B O     1 
ATOM   7624  C  CB    . TYR D 2 80  ? 104.895 81.953  102.195 1.00 19.99  ? 80   TYR B CB    1 
ATOM   7625  C  CG    . TYR D 2 80  ? 104.285 82.170  100.832 1.00 28.56  ? 80   TYR B CG    1 
ATOM   7626  C  CD1   . TYR D 2 80  ? 105.069 82.188  99.689  1.00 34.56  ? 80   TYR B CD1   1 
ATOM   7627  C  CD2   . TYR D 2 80  ? 102.914 82.446  100.693 1.00 37.03  ? 80   TYR B CD2   1 
ATOM   7628  C  CE1   . TYR D 2 80  ? 104.511 82.486  98.433  1.00 35.00  ? 80   TYR B CE1   1 
ATOM   7629  C  CE2   . TYR D 2 80  ? 102.346 82.740  99.448  1.00 28.05  ? 80   TYR B CE2   1 
ATOM   7630  C  CZ    . TYR D 2 80  ? 103.152 82.766  98.319  1.00 38.49  ? 80   TYR B CZ    1 
ATOM   7631  O  OH    . TYR D 2 80  ? 102.620 83.111  97.086  1.00 33.93  ? 80   TYR B OH    1 
ATOM   7632  N  N     . ARG D 2 81  ? 106.444 83.947  104.863 1.00 34.10  ? 81   ARG B N     1 
ATOM   7633  C  CA    . ARG D 2 81  ? 106.799 83.992  106.273 1.00 35.92  ? 81   ARG B CA    1 
ATOM   7634  C  C     . ARG D 2 81  ? 106.704 85.481  106.582 1.00 37.06  ? 81   ARG B C     1 
ATOM   7635  O  O     . ARG D 2 81  ? 107.343 86.304  105.927 1.00 40.39  ? 81   ARG B O     1 
ATOM   7636  C  CB    . ARG D 2 81  ? 108.229 83.512  106.518 1.00 33.96  ? 81   ARG B CB    1 
ATOM   7637  C  CG    . ARG D 2 81  ? 108.544 82.110  106.013 1.00 36.93  ? 81   ARG B CG    1 
ATOM   7638  C  CD    . ARG D 2 81  ? 109.982 81.729  106.377 1.00 34.58  ? 81   ARG B CD    1 
ATOM   7639  N  NE    . ARG D 2 81  ? 110.263 80.302  106.215 1.00 36.71  ? 81   ARG B NE    1 
ATOM   7640  C  CZ    . ARG D 2 81  ? 110.661 79.718  105.083 1.00 45.32  ? 81   ARG B CZ    1 
ATOM   7641  N  NH1   . ARG D 2 81  ? 110.846 80.418  103.968 1.00 53.58  ? 81   ARG B NH1   1 
ATOM   7642  N  NH2   . ARG D 2 81  ? 110.873 78.414  105.061 1.00 48.14  ? 81   ARG B NH2   1 
ATOM   7643  N  N     . GLN D 2 82  ? 105.912 85.853  107.572 1.00 35.55  ? 82   GLN B N     1 
ATOM   7644  C  CA    . GLN D 2 82  ? 105.769 87.271  107.855 1.00 42.99  ? 82   GLN B CA    1 
ATOM   7645  C  C     . GLN D 2 82  ? 107.046 87.922  108.394 1.00 39.44  ? 82   GLN B C     1 
ATOM   7646  O  O     . GLN D 2 82  ? 107.203 89.137  108.341 1.00 39.76  ? 82   GLN B O     1 
ATOM   7647  C  CB    . GLN D 2 82  ? 104.576 87.499  108.807 1.00 43.63  ? 82   GLN B CB    1 
ATOM   7648  C  CG    . GLN D 2 82  ? 103.247 86.988  108.224 1.00 37.87  ? 82   GLN B CG    1 
ATOM   7649  C  CD    . GLN D 2 82  ? 102.026 87.367  109.042 1.00 34.84  ? 82   GLN B CD    1 
ATOM   7650  O  OE1   . GLN D 2 82  ? 101.960 87.123  110.254 1.00 33.46  ? 82   GLN B OE1   1 
ATOM   7651  N  NE2   . GLN D 2 82  ? 101.044 87.956  108.378 1.00 28.92  ? 82   GLN B NE2   1 
ATOM   7652  N  N     . SER D 2 83  ? 107.972 87.109  108.880 1.00 38.08  ? 83   SER B N     1 
ATOM   7653  C  CA    . SER D 2 83  ? 109.220 87.632  109.430 1.00 39.93  ? 83   SER B CA    1 
ATOM   7654  C  C     . SER D 2 83  ? 110.112 88.142  108.305 1.00 44.59  ? 83   SER B C     1 
ATOM   7655  O  O     . SER D 2 83  ? 111.032 88.934  108.520 1.00 41.83  ? 83   SER B O     1 
ATOM   7656  C  CB    . SER D 2 83  ? 109.937 86.534  110.191 1.00 35.73  ? 83   SER B CB    1 
ATOM   7657  O  OG    . SER D 2 83  ? 110.186 85.462  109.313 1.00 32.01  ? 83   SER B OG    1 
ATOM   7658  N  N     . GLU D 2 84  ? 109.827 87.677  107.094 1.00 50.81  ? 84   GLU B N     1 
ATOM   7659  C  CA    . GLU D 2 84  ? 110.582 88.087  105.920 1.00 44.78  ? 84   GLU B CA    1 
ATOM   7660  C  C     . GLU D 2 84  ? 109.952 89.294  105.223 1.00 44.49  ? 84   GLU B C     1 
ATOM   7661  O  O     . GLU D 2 84  ? 110.496 89.789  104.246 1.00 44.84  ? 84   GLU B O     1 
ATOM   7662  C  CB    . GLU D 2 84  ? 110.690 86.916  104.942 1.00 39.31  ? 84   GLU B CB    1 
ATOM   7663  C  CG    . GLU D 2 84  ? 111.256 85.678  105.592 1.00 38.88  ? 84   GLU B CG    1 
ATOM   7664  C  CD    . GLU D 2 84  ? 111.371 84.497  104.649 1.00 50.11  ? 84   GLU B CD    1 
ATOM   7665  O  OE1   . GLU D 2 84  ? 110.535 84.398  103.720 1.00 49.68  ? 84   GLU B OE1   1 
ATOM   7666  O  OE2   . GLU D 2 84  ? 112.289 83.659  104.854 1.00 53.26  ? 84   GLU B OE2   1 
ATOM   7667  N  N     . ARG D 2 85  ? 108.823 89.789  105.731 1.00 46.94  ? 85   ARG B N     1 
ATOM   7668  C  CA    . ARG D 2 85  ? 108.168 90.924  105.092 1.00 37.01  ? 85   ARG B CA    1 
ATOM   7669  C  C     . ARG D 2 85  ? 107.924 92.153  105.985 1.00 39.51  ? 85   ARG B C     1 
ATOM   7670  O  O     . ARG D 2 85  ? 107.020 92.983  105.728 1.00 36.53  ? 85   ARG B O     1 
ATOM   7671  C  CB    . ARG D 2 85  ? 106.863 90.440  104.421 1.00 38.17  ? 85   ARG B CB    1 
ATOM   7672  C  CG    . ARG D 2 85  ? 105.981 89.538  105.259 1.00 56.01  ? 85   ARG B CG    1 
ATOM   7673  C  CD    . ARG D 2 85  ? 104.621 89.322  104.570 1.00 50.72  ? 85   ARG B CD    1 
ATOM   7674  N  NE    . ARG D 2 85  ? 104.834 88.806  103.236 1.00 43.35  ? 85   ARG B NE    1 
ATOM   7675  C  CZ    . ARG D 2 85  ? 104.073 89.080  102.187 1.00 36.37  ? 85   ARG B CZ    1 
ATOM   7676  N  NH1   . ARG D 2 85  ? 103.029 89.872  102.314 1.00 24.14  ? 85   ARG B NH1   1 
ATOM   7677  N  NH2   . ARG D 2 85  ? 104.381 88.567  101.000 1.00 37.61  ? 85   ARG B NH2   1 
ATOM   7678  N  N     . LEU D 2 86  ? 108.756 92.290  107.015 1.00 40.31  ? 86   LEU B N     1 
ATOM   7679  C  CA    . LEU D 2 86  ? 108.646 93.415  107.940 1.00 46.76  ? 86   LEU B CA    1 
ATOM   7680  C  C     . LEU D 2 86  ? 108.539 94.797  107.287 1.00 48.65  ? 86   LEU B C     1 
ATOM   7681  O  O     . LEU D 2 86  ? 107.633 95.561  107.615 1.00 56.01  ? 86   LEU B O     1 
ATOM   7682  C  CB    . LEU D 2 86  ? 109.820 93.393  108.914 1.00 46.97  ? 86   LEU B CB    1 
ATOM   7683  C  CG    . LEU D 2 86  ? 109.538 92.855  110.327 1.00 61.90  ? 86   LEU B CG    1 
ATOM   7684  C  CD1   . LEU D 2 86  ? 108.355 91.876  110.353 1.00 46.50  ? 86   LEU B CD1   1 
ATOM   7685  C  CD2   . LEU D 2 86  ? 110.821 92.201  110.848 1.00 59.18  ? 86   LEU B CD2   1 
ATOM   7686  N  N     . PRO D 2 87  ? 109.445 95.126  106.344 1.00 47.16  ? 87   PRO B N     1 
ATOM   7687  C  CA    . PRO D 2 87  ? 109.457 96.419  105.644 1.00 53.90  ? 87   PRO B CA    1 
ATOM   7688  C  C     . PRO D 2 87  ? 108.093 96.755  105.061 1.00 53.84  ? 87   PRO B C     1 
ATOM   7689  O  O     . PRO D 2 87  ? 107.656 97.915  105.049 1.00 52.55  ? 87   PRO B O     1 
ATOM   7690  C  CB    . PRO D 2 87  ? 110.495 96.206  104.544 1.00 55.71  ? 87   PRO B CB    1 
ATOM   7691  C  CG    . PRO D 2 87  ? 111.430 95.198  105.152 1.00 59.68  ? 87   PRO B CG    1 
ATOM   7692  C  CD    . PRO D 2 87  ? 110.469 94.229  105.781 1.00 52.14  ? 87   PRO B CD    1 
ATOM   7693  N  N     . LEU D 2 88  ? 107.434 95.714  104.570 1.00 48.53  ? 88   LEU B N     1 
ATOM   7694  C  CA    . LEU D 2 88  ? 106.118 95.839  103.977 1.00 53.83  ? 88   LEU B CA    1 
ATOM   7695  C  C     . LEU D 2 88  ? 105.127 96.454  104.974 1.00 52.66  ? 88   LEU B C     1 
ATOM   7696  O  O     . LEU D 2 88  ? 104.442 97.433  104.677 1.00 47.77  ? 88   LEU B O     1 
ATOM   7697  C  CB    . LEU D 2 88  ? 105.663 94.452  103.537 1.00 53.43  ? 88   LEU B CB    1 
ATOM   7698  C  CG    . LEU D 2 88  ? 104.819 94.373  102.270 1.00 62.16  ? 88   LEU B CG    1 
ATOM   7699  C  CD1   . LEU D 2 88  ? 105.414 95.247  101.170 1.00 55.87  ? 88   LEU B CD1   1 
ATOM   7700  C  CD2   . LEU D 2 88  ? 104.763 92.924  101.831 1.00 60.71  ? 88   LEU B CD2   1 
ATOM   7701  N  N     . TYR D 2 89  ? 105.078 95.875  106.167 1.00 56.26  ? 89   TYR B N     1 
ATOM   7702  C  CA    . TYR D 2 89  ? 104.181 96.339  107.218 1.00 53.96  ? 89   TYR B CA    1 
ATOM   7703  C  C     . TYR D 2 89  ? 104.497 97.773  107.655 1.00 56.17  ? 89   TYR B C     1 
ATOM   7704  O  O     . TYR D 2 89  ? 103.576 98.582  107.886 1.00 47.12  ? 89   TYR B O     1 
ATOM   7705  C  CB    . TYR D 2 89  ? 104.276 95.384  108.406 1.00 54.36  ? 89   TYR B CB    1 
ATOM   7706  C  CG    . TYR D 2 89  ? 104.101 93.928  108.018 1.00 45.01  ? 89   TYR B CG    1 
ATOM   7707  C  CD1   . TYR D 2 89  ? 102.949 93.492  107.357 1.00 44.03  ? 89   TYR B CD1   1 
ATOM   7708  C  CD2   . TYR D 2 89  ? 105.070 92.981  108.350 1.00 42.59  ? 89   TYR B CD2   1 
ATOM   7709  C  CE1   . TYR D 2 89  ? 102.762 92.136  107.038 1.00 44.69  ? 89   TYR B CE1   1 
ATOM   7710  C  CE2   . TYR D 2 89  ? 104.897 91.627  108.041 1.00 44.81  ? 89   TYR B CE2   1 
ATOM   7711  C  CZ    . TYR D 2 89  ? 103.741 91.214  107.387 1.00 46.33  ? 89   TYR B CZ    1 
ATOM   7712  O  OH    . TYR D 2 89  ? 103.571 89.883  107.103 1.00 44.18  ? 89   TYR B OH    1 
ATOM   7713  N  N     . GLN D 2 90  ? 105.792 98.085  107.760 1.00 51.36  ? 90   GLN B N     1 
ATOM   7714  C  CA    . GLN D 2 90  ? 106.226 99.430  108.151 1.00 54.99  ? 90   GLN B CA    1 
ATOM   7715  C  C     . GLN D 2 90  ? 105.648 100.456 107.190 1.00 48.16  ? 90   GLN B C     1 
ATOM   7716  O  O     . GLN D 2 90  ? 105.045 101.447 107.603 1.00 50.20  ? 90   GLN B O     1 
ATOM   7717  C  CB    . GLN D 2 90  ? 107.760 99.518  108.168 1.00 63.44  ? 90   GLN B CB    1 
ATOM   7718  C  CG    . GLN D 2 90  ? 108.371 99.333  109.574 1.00 81.27  ? 90   GLN B CG    1 
ATOM   7719  C  CD    . GLN D 2 90  ? 109.707 98.576  109.584 1.00 89.61  ? 90   GLN B CD    1 
ATOM   7720  O  OE1   . GLN D 2 90  ? 110.693 99.011  108.977 1.00 93.73  ? 90   GLN B OE1   1 
ATOM   7721  N  NE2   . GLN D 2 90  ? 109.739 97.437  110.282 1.00 84.19  ? 90   GLN B NE2   1 
ATOM   7722  N  N     . LYS D 2 91  ? 105.809 100.192 105.901 1.00 46.18  ? 91   LYS B N     1 
ATOM   7723  C  CA    . LYS D 2 91  ? 105.301 101.075 104.847 1.00 49.21  ? 91   LYS B CA    1 
ATOM   7724  C  C     . LYS D 2 91  ? 103.765 101.295 104.934 1.00 49.19  ? 91   LYS B C     1 
ATOM   7725  O  O     . LYS D 2 91  ? 103.270 102.429 104.836 1.00 37.51  ? 91   LYS B O     1 
ATOM   7726  C  CB    . LYS D 2 91  ? 105.722 100.489 103.488 1.00 49.51  ? 91   LYS B CB    1 
ATOM   7727  C  CG    . LYS D 2 91  ? 104.842 100.819 102.295 1.00 59.60  ? 91   LYS B CG    1 
ATOM   7728  C  CD    . LYS D 2 91  ? 105.184 99.896  101.116 1.00 68.19  ? 91   LYS B CD    1 
ATOM   7729  C  CE    . LYS D 2 91  ? 104.195 100.030 99.959  1.00 70.60  ? 91   LYS B CE    1 
ATOM   7730  N  NZ    . LYS D 2 91  ? 104.498 99.043  98.874  1.00 73.24  ? 91   LYS B NZ    1 
ATOM   7731  N  N     . TYR D 2 92  ? 103.013 100.212 105.133 1.00 51.98  ? 92   TYR B N     1 
ATOM   7732  C  CA    . TYR D 2 92  ? 101.559 100.324 105.233 1.00 48.60  ? 92   TYR B CA    1 
ATOM   7733  C  C     . TYR D 2 92  ? 101.139 101.027 106.529 1.00 48.50  ? 92   TYR B C     1 
ATOM   7734  O  O     . TYR D 2 92  ? 100.142 101.767 106.554 1.00 41.87  ? 92   TYR B O     1 
ATOM   7735  C  CB    . TYR D 2 92  ? 100.907 98.935  105.115 1.00 43.06  ? 92   TYR B CB    1 
ATOM   7736  C  CG    . TYR D 2 92  ? 100.861 98.422  103.697 1.00 35.62  ? 92   TYR B CG    1 
ATOM   7737  C  CD1   . TYR D 2 92  ? 101.761 97.459  103.239 1.00 36.99  ? 92   TYR B CD1   1 
ATOM   7738  C  CD2   . TYR D 2 92  ? 99.940  98.934  102.795 1.00 44.63  ? 92   TYR B CD2   1 
ATOM   7739  C  CE1   . TYR D 2 92  ? 101.737 97.028  101.922 1.00 33.66  ? 92   TYR B CE1   1 
ATOM   7740  C  CE2   . TYR D 2 92  ? 99.908  98.514  101.480 1.00 39.89  ? 92   TYR B CE2   1 
ATOM   7741  C  CZ    . TYR D 2 92  ? 100.802 97.563  101.044 1.00 40.90  ? 92   TYR B CZ    1 
ATOM   7742  O  OH    . TYR D 2 92  ? 100.720 97.147  99.728  1.00 38.51  ? 92   TYR B OH    1 
ATOM   7743  N  N     . ALA D 2 93  ? 101.895 100.805 107.601 1.00 44.62  ? 93   ALA B N     1 
ATOM   7744  C  CA    . ALA D 2 93  ? 101.586 101.462 108.863 1.00 51.42  ? 93   ALA B CA    1 
ATOM   7745  C  C     . ALA D 2 93  ? 101.653 102.974 108.594 1.00 58.50  ? 93   ALA B C     1 
ATOM   7746  O  O     . ALA D 2 93  ? 100.697 103.735 108.869 1.00 48.95  ? 93   ALA B O     1 
ATOM   7747  C  CB    . ALA D 2 93  ? 102.602 101.066 109.910 1.00 47.62  ? 93   ALA B CB    1 
ATOM   7748  N  N     . GLU D 2 94  ? 102.790 103.393 108.039 1.00 55.77  ? 94   GLU B N     1 
ATOM   7749  C  CA    . GLU D 2 94  ? 103.012 104.789 107.688 1.00 56.68  ? 94   GLU B CA    1 
ATOM   7750  C  C     . GLU D 2 94  ? 101.937 105.267 106.717 1.00 55.16  ? 94   GLU B C     1 
ATOM   7751  O  O     . GLU D 2 94  ? 101.478 106.400 106.810 1.00 57.10  ? 94   GLU B O     1 
ATOM   7752  C  CB    . GLU D 2 94  ? 104.389 104.947 107.069 1.00 57.20  ? 94   GLU B CB    1 
ATOM   7753  C  CG    . GLU D 2 94  ? 105.499 104.731 108.070 1.00 68.51  ? 94   GLU B CG    1 
ATOM   7754  C  CD    . GLU D 2 94  ? 106.770 104.248 107.415 1.00 77.14  ? 94   GLU B CD    1 
ATOM   7755  O  OE1   . GLU D 2 94  ? 107.093 104.744 106.309 1.00 80.18  ? 94   GLU B OE1   1 
ATOM   7756  O  OE2   . GLU D 2 94  ? 107.443 103.377 108.011 1.00 81.68  ? 94   GLU B OE2   1 
ATOM   7757  N  N     . GLU D 2 95  ? 101.528 104.408 105.790 1.00 55.56  ? 95   GLU B N     1 
ATOM   7758  C  CA    . GLU D 2 95  ? 100.482 104.781 104.839 1.00 57.35  ? 95   GLU B CA    1 
ATOM   7759  C  C     . GLU D 2 95  ? 99.180  105.124 105.567 1.00 55.95  ? 95   GLU B C     1 
ATOM   7760  O  O     . GLU D 2 95  ? 98.458  106.037 105.172 1.00 50.71  ? 95   GLU B O     1 
ATOM   7761  C  CB    . GLU D 2 95  ? 100.219 103.641 103.864 1.00 65.31  ? 95   GLU B CB    1 
ATOM   7762  C  CG    . GLU D 2 95  ? 98.959  103.818 103.015 1.00 74.58  ? 95   GLU B CG    1 
ATOM   7763  C  CD    . GLU D 2 95  ? 99.163  104.741 101.825 1.00 84.83  ? 95   GLU B CD    1 
ATOM   7764  O  OE1   . GLU D 2 95  ? 99.292  105.969 102.019 1.00 82.58  ? 95   GLU B OE1   1 
ATOM   7765  O  OE2   . GLU D 2 95  ? 99.198  104.230 100.684 1.00 93.87  ? 95   GLU B OE2   1 
ATOM   7766  N  N     . LEU D 2 96  ? 98.873  104.379 106.626 1.00 56.31  ? 96   LEU B N     1 
ATOM   7767  C  CA    . LEU D 2 96  ? 97.652  104.634 107.391 1.00 55.59  ? 96   LEU B CA    1 
ATOM   7768  C  C     . LEU D 2 96  ? 97.780  105.970 108.122 1.00 49.70  ? 96   LEU B C     1 
ATOM   7769  O  O     . LEU D 2 96  ? 96.806  106.707 108.251 1.00 47.16  ? 96   LEU B O     1 
ATOM   7770  C  CB    . LEU D 2 96  ? 97.392  103.494 108.390 1.00 46.26  ? 96   LEU B CB    1 
ATOM   7771  C  CG    . LEU D 2 96  ? 96.967  102.119 107.847 1.00 41.00  ? 96   LEU B CG    1 
ATOM   7772  C  CD1   . LEU D 2 96  ? 97.091  101.105 108.967 1.00 31.08  ? 96   LEU B CD1   1 
ATOM   7773  C  CD2   . LEU D 2 96  ? 95.530  102.155 107.311 1.00 32.43  ? 96   LEU B CD2   1 
ATOM   7774  N  N     . LEU D 2 97  ? 98.997  106.270 108.576 1.00 54.35  ? 97   LEU B N     1 
ATOM   7775  C  CA    . LEU D 2 97  ? 99.311  107.513 109.285 1.00 56.65  ? 97   LEU B CA    1 
ATOM   7776  C  C     . LEU D 2 97  ? 98.946  108.701 108.414 1.00 60.90  ? 97   LEU B C     1 
ATOM   7777  O  O     . LEU D 2 97  ? 98.179  109.584 108.812 1.00 61.34  ? 97   LEU B O     1 
ATOM   7778  C  CB    . LEU D 2 97  ? 100.803 107.567 109.584 1.00 56.77  ? 97   LEU B CB    1 
ATOM   7779  C  CG    . LEU D 2 97  ? 101.192 107.648 111.049 1.00 53.81  ? 97   LEU B CG    1 
ATOM   7780  C  CD1   . LEU D 2 97  ? 100.397 106.624 111.848 1.00 64.19  ? 97   LEU B CD1   1 
ATOM   7781  C  CD2   . LEU D 2 97  ? 102.684 107.418 111.168 1.00 54.53  ? 97   LEU B CD2   1 
ATOM   7782  N  N     . LYS D 2 98  ? 99.517  108.704 107.217 1.00 60.97  ? 98   LYS B N     1 
ATOM   7783  C  CA    . LYS D 2 98  ? 99.272  109.751 106.244 1.00 66.32  ? 98   LYS B CA    1 
ATOM   7784  C  C     . LYS D 2 98  ? 97.779  109.879 106.018 1.00 62.78  ? 98   LYS B C     1 
ATOM   7785  O  O     . LYS D 2 98  ? 97.233  110.979 106.043 1.00 70.74  ? 98   LYS B O     1 
ATOM   7786  C  CB    . LYS D 2 98  ? 99.984  109.420 104.922 1.00 66.29  ? 98   LYS B CB    1 
ATOM   7787  C  CG    . LYS D 2 98  ? 101.447 109.873 104.868 1.00 83.04  ? 98   LYS B CG    1 
ATOM   7788  C  CD    . LYS D 2 98  ? 102.256 109.419 106.105 1.00 92.26  ? 98   LYS B CD    1 
ATOM   7789  C  CE    . LYS D 2 98  ? 103.589 110.185 106.264 1.00 95.49  ? 98   LYS B CE    1 
ATOM   7790  N  NZ    . LYS D 2 98  ? 104.356 109.787 107.493 1.00 81.91  ? 98   LYS B NZ    1 
ATOM   7791  N  N     . ARG D 2 99  ? 97.118  108.746 105.823 1.00 58.96  ? 99   ARG B N     1 
ATOM   7792  C  CA    . ARG D 2 99  ? 95.686  108.746 105.573 1.00 62.94  ? 99   ARG B CA    1 
ATOM   7793  C  C     . ARG D 2 99  ? 94.893  109.131 106.811 1.00 63.96  ? 99   ARG B C     1 
ATOM   7794  O  O     . ARG D 2 99  ? 93.660  109.206 106.771 1.00 60.53  ? 99   ARG B O     1 
ATOM   7795  C  CB    . ARG D 2 99  ? 95.244  107.372 105.067 1.00 70.04  ? 99   ARG B CB    1 
ATOM   7796  C  CG    . ARG D 2 99  ? 95.889  106.950 103.738 1.00 68.88  ? 99   ARG B CG    1 
ATOM   7797  C  CD    . ARG D 2 99  ? 95.619  105.485 103.454 1.00 72.39  ? 99   ARG B CD    1 
ATOM   7798  N  NE    . ARG D 2 99  ? 94.734  105.286 102.312 1.00 72.36  ? 99   ARG B NE    1 
ATOM   7799  C  CZ    . ARG D 2 99  ? 95.129  105.338 101.044 1.00 77.89  ? 99   ARG B CZ    1 
ATOM   7800  N  NH1   . ARG D 2 99  ? 96.400  105.581 100.757 1.00 80.57  ? 99   ARG B NH1   1 
ATOM   7801  N  NH2   . ARG D 2 99  ? 94.256  105.144 100.061 1.00 73.48  ? 99   ARG B NH2   1 
ATOM   7802  N  N     . GLY D 2 100 ? 95.606  109.380 107.905 1.00 58.89  ? 100  GLY B N     1 
ATOM   7803  C  CA    . GLY D 2 100 ? 94.944  109.766 109.137 1.00 69.71  ? 100  GLY B CA    1 
ATOM   7804  C  C     . GLY D 2 100 ? 94.090  108.684 109.791 1.00 70.48  ? 100  GLY B C     1 
ATOM   7805  O  O     . GLY D 2 100 ? 93.177  108.992 110.566 1.00 64.47  ? 100  GLY B O     1 
ATOM   7806  N  N     . TRP D 2 101 ? 94.373  107.422 109.469 1.00 67.36  ? 101  TRP B N     1 
ATOM   7807  C  CA    . TRP D 2 101 ? 93.653  106.291 110.050 1.00 59.92  ? 101  TRP B CA    1 
ATOM   7808  C  C     . TRP D 2 101 ? 94.464  105.638 111.184 1.00 56.22  ? 101  TRP B C     1 
ATOM   7809  O  O     . TRP D 2 101 ? 94.026  104.657 111.767 1.00 55.03  ? 101  TRP B O     1 
ATOM   7810  C  CB    . TRP D 2 101 ? 93.345  105.232 108.989 1.00 54.86  ? 101  TRP B CB    1 
ATOM   7811  C  CG    . TRP D 2 101 ? 92.077  105.443 108.242 1.00 50.41  ? 101  TRP B CG    1 
ATOM   7812  C  CD1   . TRP D 2 101 ? 91.919  106.106 107.065 1.00 55.23  ? 101  TRP B CD1   1 
ATOM   7813  C  CD2   . TRP D 2 101 ? 90.780  104.982 108.619 1.00 45.97  ? 101  TRP B CD2   1 
ATOM   7814  N  NE1   . TRP D 2 101 ? 90.597  106.087 106.677 1.00 46.81  ? 101  TRP B NE1   1 
ATOM   7815  C  CE2   . TRP D 2 101 ? 89.876  105.406 107.617 1.00 47.81  ? 101  TRP B CE2   1 
ATOM   7816  C  CE3   . TRP D 2 101 ? 90.289  104.252 109.709 1.00 51.17  ? 101  TRP B CE3   1 
ATOM   7817  C  CZ2   . TRP D 2 101 ? 88.506  105.126 107.673 1.00 44.80  ? 101  TRP B CZ2   1 
ATOM   7818  C  CZ3   . TRP D 2 101 ? 88.926  103.970 109.767 1.00 37.32  ? 101  TRP B CZ3   1 
ATOM   7819  C  CH2   . TRP D 2 101 ? 88.052  104.407 108.755 1.00 47.80  ? 101  TRP B CH2   1 
ATOM   7820  N  N     . ALA D 2 102 ? 95.647  106.174 111.474 1.00 52.32  ? 102  ALA B N     1 
ATOM   7821  C  CA    . ALA D 2 102 ? 96.512  105.660 112.540 1.00 50.60  ? 102  ALA B CA    1 
ATOM   7822  C  C     . ALA D 2 102 ? 97.240  106.839 113.160 1.00 53.55  ? 102  ALA B C     1 
ATOM   7823  O  O     . ALA D 2 102 ? 97.307  107.902 112.560 1.00 61.46  ? 102  ALA B O     1 
ATOM   7824  C  CB    . ALA D 2 102 ? 97.523  104.696 111.970 1.00 37.26  ? 102  ALA B CB    1 
ATOM   7825  N  N     . TYR D 2 103 ? 97.785  106.673 114.355 1.00 52.36  ? 103  TYR B N     1 
ATOM   7826  C  CA    . TYR D 2 103 ? 98.527  107.763 114.972 1.00 46.54  ? 103  TYR B CA    1 
ATOM   7827  C  C     . TYR D 2 103 ? 99.627  107.163 115.781 1.00 56.44  ? 103  TYR B C     1 
ATOM   7828  O  O     . TYR D 2 103 ? 99.528  106.007 116.191 1.00 59.35  ? 103  TYR B O     1 
ATOM   7829  C  CB    . TYR D 2 103 ? 97.635  108.597 115.885 1.00 46.29  ? 103  TYR B CB    1 
ATOM   7830  C  CG    . TYR D 2 103 ? 96.986  107.835 117.032 1.00 55.24  ? 103  TYR B CG    1 
ATOM   7831  C  CD1   . TYR D 2 103 ? 97.676  107.580 118.219 1.00 53.00  ? 103  TYR B CD1   1 
ATOM   7832  C  CD2   . TYR D 2 103 ? 95.679  107.369 116.924 1.00 49.02  ? 103  TYR B CD2   1 
ATOM   7833  C  CE1   . TYR D 2 103 ? 97.074  106.878 119.265 1.00 52.00  ? 103  TYR B CE1   1 
ATOM   7834  C  CE2   . TYR D 2 103 ? 95.077  106.671 117.953 1.00 55.19  ? 103  TYR B CE2   1 
ATOM   7835  C  CZ    . TYR D 2 103 ? 95.772  106.424 119.121 1.00 58.07  ? 103  TYR B CZ    1 
ATOM   7836  O  OH    . TYR D 2 103 ? 95.155  105.705 120.131 1.00 59.48  ? 103  TYR B OH    1 
ATOM   7837  N  N     . ARG D 2 104 ? 100.679 107.941 116.018 1.00 64.51  ? 104  ARG B N     1 
ATOM   7838  C  CA    . ARG D 2 104 ? 101.803 107.464 116.818 1.00 66.21  ? 104  ARG B CA    1 
ATOM   7839  C  C     . ARG D 2 104 ? 101.496 107.681 118.307 1.00 67.59  ? 104  ARG B C     1 
ATOM   7840  O  O     . ARG D 2 104 ? 100.846 108.661 118.684 1.00 69.94  ? 104  ARG B O     1 
ATOM   7841  C  CB    . ARG D 2 104 ? 103.074 108.209 116.425 1.00 68.19  ? 104  ARG B CB    1 
ATOM   7842  C  CG    . ARG D 2 104 ? 103.163 108.494 114.933 1.00 72.36  ? 104  ARG B CG    1 
ATOM   7843  C  CD    . ARG D 2 104 ? 104.500 109.114 114.576 1.00 69.83  ? 104  ARG B CD    1 
ATOM   7844  N  NE    . ARG D 2 104 ? 105.482 108.123 114.151 1.00 71.36  ? 104  ARG B NE    1 
ATOM   7845  C  CZ    . ARG D 2 104 ? 105.823 107.920 112.881 1.00 70.51  ? 104  ARG B CZ    1 
ATOM   7846  N  NH1   . ARG D 2 104 ? 105.262 108.642 111.917 1.00 53.99  ? 104  ARG B NH1   1 
ATOM   7847  N  NH2   . ARG D 2 104 ? 106.722 106.993 112.577 1.00 74.38  ? 104  ARG B NH2   1 
ATOM   7848  N  N     . ALA D 2 105 ? 101.949 106.753 119.143 1.00 63.20  ? 105  ALA B N     1 
ATOM   7849  C  CA    . ALA D 2 105 ? 101.720 106.824 120.580 1.00 63.63  ? 105  ALA B CA    1 
ATOM   7850  C  C     . ALA D 2 105 ? 103.035 106.443 121.238 1.00 69.62  ? 105  ALA B C     1 
ATOM   7851  O  O     . ALA D 2 105 ? 103.597 105.384 120.930 1.00 67.73  ? 105  ALA B O     1 
ATOM   7852  C  CB    . ALA D 2 105 ? 100.626 105.848 120.978 1.00 57.59  ? 105  ALA B CB    1 
ATOM   7853  N  N     . PHE D 2 106 ? 103.524 107.290 122.150 1.00 74.62  ? 106  PHE B N     1 
ATOM   7854  C  CA    . PHE D 2 106 ? 104.818 107.038 122.800 1.00 73.19  ? 106  PHE B CA    1 
ATOM   7855  C  C     . PHE D 2 106 ? 104.815 106.516 124.238 1.00 70.98  ? 106  PHE B C     1 
ATOM   7856  O  O     . PHE D 2 106 ? 105.881 106.342 124.819 1.00 73.80  ? 106  PHE B O     1 
ATOM   7857  C  CB    . PHE D 2 106 ? 105.693 108.300 122.744 1.00 65.87  ? 106  PHE B CB    1 
ATOM   7858  C  CG    . PHE D 2 106 ? 105.701 108.978 121.400 1.00 61.28  ? 106  PHE B CG    1 
ATOM   7859  C  CD1   . PHE D 2 106 ? 104.651 109.817 121.020 1.00 53.21  ? 106  PHE B CD1   1 
ATOM   7860  C  CD2   . PHE D 2 106 ? 106.737 108.754 120.504 1.00 52.75  ? 106  PHE B CD2   1 
ATOM   7861  C  CE1   . PHE D 2 106 ? 104.628 110.422 119.769 1.00 49.75  ? 106  PHE B CE1   1 
ATOM   7862  C  CE2   . PHE D 2 106 ? 106.727 109.354 119.245 1.00 58.45  ? 106  PHE B CE2   1 
ATOM   7863  C  CZ    . PHE D 2 106 ? 105.667 110.192 118.876 1.00 59.19  ? 106  PHE B CZ    1 
ATOM   7864  N  N     . GLU D 2 107 ? 103.646 106.257 124.808 1.00 65.74  ? 107  GLU B N     1 
ATOM   7865  C  CA    . GLU D 2 107 ? 103.580 105.765 126.175 1.00 67.87  ? 107  GLU B CA    1 
ATOM   7866  C  C     . GLU D 2 107 ? 104.456 104.542 126.340 1.00 75.29  ? 107  GLU B C     1 
ATOM   7867  O  O     . GLU D 2 107 ? 104.560 103.717 125.431 1.00 83.20  ? 107  GLU B O     1 
ATOM   7868  C  CB    . GLU D 2 107 ? 102.145 105.397 126.556 1.00 67.11  ? 107  GLU B CB    1 
ATOM   7869  C  CG    . GLU D 2 107 ? 101.139 106.527 126.452 1.00 72.64  ? 107  GLU B CG    1 
ATOM   7870  C  CD    . GLU D 2 107 ? 100.923 107.008 125.030 1.00 74.05  ? 107  GLU B CD    1 
ATOM   7871  O  OE1   . GLU D 2 107 ? 100.101 107.928 124.820 1.00 77.76  ? 107  GLU B OE1   1 
ATOM   7872  O  OE2   . GLU D 2 107 ? 101.570 106.468 124.118 1.00 75.22  ? 107  GLU B OE2   1 
ATOM   7873  N  N     . THR D 2 108 ? 105.089 104.427 127.500 1.00 78.93  ? 108  THR B N     1 
ATOM   7874  C  CA    . THR D 2 108 ? 105.936 103.282 127.786 1.00 80.62  ? 108  THR B CA    1 
ATOM   7875  C  C     . THR D 2 108 ? 104.999 102.191 128.279 1.00 82.28  ? 108  THR B C     1 
ATOM   7876  O  O     . THR D 2 108 ? 103.839 102.462 128.604 1.00 84.03  ? 108  THR B O     1 
ATOM   7877  C  CB    . THR D 2 108 ? 106.947 103.606 128.886 1.00 85.21  ? 108  THR B CB    1 
ATOM   7878  O  OG1   . THR D 2 108 ? 106.319 103.484 130.170 1.00 93.98  ? 108  THR B OG1   1 
ATOM   7879  C  CG2   . THR D 2 108 ? 107.448 105.034 128.720 1.00 88.88  ? 108  THR B CG2   1 
ATOM   7880  N  N     . PRO D 2 109 ? 105.473 100.940 128.320 1.00 84.91  ? 109  PRO B N     1 
ATOM   7881  C  CA    . PRO D 2 109 ? 104.616 99.846  128.791 1.00 88.54  ? 109  PRO B CA    1 
ATOM   7882  C  C     . PRO D 2 109 ? 104.055 100.141 130.185 1.00 90.91  ? 109  PRO B C     1 
ATOM   7883  O  O     . PRO D 2 109 ? 102.895 99.850  130.480 1.00 93.21  ? 109  PRO B O     1 
ATOM   7884  C  CB    . PRO D 2 109 ? 105.563 98.647  128.773 1.00 89.63  ? 109  PRO B CB    1 
ATOM   7885  C  CG    . PRO D 2 109 ? 106.446 98.953  127.580 1.00 82.08  ? 109  PRO B CG    1 
ATOM   7886  C  CD    . PRO D 2 109 ? 106.746 100.427 127.779 1.00 85.04  ? 109  PRO B CD    1 
ATOM   7887  N  N     . GLU D 2 110 ? 104.899 100.729 131.031 1.00 94.81  ? 110  GLU B N     1 
ATOM   7888  C  CA    . GLU D 2 110 ? 104.531 101.095 132.397 1.00 94.86  ? 110  GLU B CA    1 
ATOM   7889  C  C     . GLU D 2 110 ? 103.323 102.038 132.415 1.00 93.13  ? 110  GLU B C     1 
ATOM   7890  O  O     . GLU D 2 110 ? 102.325 101.770 133.085 1.00 90.46  ? 110  GLU B O     1 
ATOM   7891  C  CB    . GLU D 2 110 ? 105.739 101.758 133.084 1.00 100.31 ? 110  GLU B CB    1 
ATOM   7892  C  CG    . GLU D 2 110 ? 105.412 102.835 134.139 1.00 108.65 ? 110  GLU B CG    1 
ATOM   7893  C  CD    . GLU D 2 110 ? 105.366 102.312 135.573 1.00 111.42 ? 110  GLU B CD    1 
ATOM   7894  O  OE1   . GLU D 2 110 ? 106.403 101.807 136.067 1.00 109.59 ? 110  GLU B OE1   1 
ATOM   7895  O  OE2   . GLU D 2 110 ? 104.292 102.421 136.209 1.00 111.05 ? 110  GLU B OE2   1 
ATOM   7896  N  N     . GLU D 2 111 ? 103.423 103.143 131.683 1.00 90.00  ? 111  GLU B N     1 
ATOM   7897  C  CA    . GLU D 2 111 ? 102.340 104.113 131.618 1.00 91.79  ? 111  GLU B CA    1 
ATOM   7898  C  C     . GLU D 2 111 ? 101.050 103.436 131.208 1.00 93.20  ? 111  GLU B C     1 
ATOM   7899  O  O     . GLU D 2 111 ? 99.999  103.673 131.798 1.00 95.74  ? 111  GLU B O     1 
ATOM   7900  C  CB    . GLU D 2 111 ? 102.653 105.198 130.593 1.00 95.69  ? 111  GLU B CB    1 
ATOM   7901  C  CG    . GLU D 2 111 ? 103.763 106.141 130.977 1.00 103.26 ? 111  GLU B CG    1 
ATOM   7902  C  CD    . GLU D 2 111 ? 104.132 107.081 129.844 1.00 109.37 ? 111  GLU B CD    1 
ATOM   7903  O  OE1   . GLU D 2 111 ? 105.031 106.730 129.043 1.00 110.94 ? 111  GLU B OE1   1 
ATOM   7904  O  OE2   . GLU D 2 111 ? 103.512 108.164 129.745 1.00 106.78 ? 111  GLU B OE2   1 
ATOM   7905  N  N     . LEU D 2 112 ? 101.140 102.600 130.178 1.00 95.42  ? 112  LEU B N     1 
ATOM   7906  C  CA    . LEU D 2 112 ? 99.979  101.885 129.660 1.00 94.12  ? 112  LEU B CA    1 
ATOM   7907  C  C     . LEU D 2 112 ? 99.259  101.101 130.736 1.00 91.33  ? 112  LEU B C     1 
ATOM   7908  O  O     . LEU D 2 112 ? 98.043  101.186 130.863 1.00 94.24  ? 112  LEU B O     1 
ATOM   7909  C  CB    . LEU D 2 112 ? 100.387 100.916 128.550 1.00 96.36  ? 112  LEU B CB    1 
ATOM   7910  C  CG    . LEU D 2 112 ? 101.071 101.462 127.299 1.00 98.55  ? 112  LEU B CG    1 
ATOM   7911  C  CD1   . LEU D 2 112 ? 101.210 100.321 126.291 1.00 96.81  ? 112  LEU B CD1   1 
ATOM   7912  C  CD2   . LEU D 2 112 ? 100.262 102.610 126.706 1.00 98.40  ? 112  LEU B CD2   1 
ATOM   7913  N  N     . GLU D 2 113 ? 100.010 100.324 131.504 1.00 88.43  ? 113  GLU B N     1 
ATOM   7914  C  CA    . GLU D 2 113 ? 99.406  99.520  132.553 1.00 87.70  ? 113  GLU B CA    1 
ATOM   7915  C  C     . GLU D 2 113 ? 98.687  100.458 133.517 1.00 88.15  ? 113  GLU B C     1 
ATOM   7916  O  O     . GLU D 2 113 ? 97.577  100.181 133.983 1.00 85.02  ? 113  GLU B O     1 
ATOM   7917  C  CB    . GLU D 2 113 ? 100.487 98.708  133.273 1.00 92.27  ? 113  GLU B CB    1 
ATOM   7918  C  CG    . GLU D 2 113 ? 99.967  97.504  134.048 1.00 96.37  ? 113  GLU B CG    1 
ATOM   7919  C  CD    . GLU D 2 113 ? 99.053  96.620  133.213 1.00 99.45  ? 113  GLU B CD    1 
ATOM   7920  O  OE1   . GLU D 2 113 ? 97.895  97.020  132.961 1.00 101.95 ? 113  GLU B OE1   1 
ATOM   7921  O  OE2   . GLU D 2 113 ? 99.492  95.527  132.801 1.00 99.55  ? 113  GLU B OE2   1 
ATOM   7922  N  N     . GLN D 2 114 ? 99.327  101.586 133.797 1.00 89.55  ? 114  GLN B N     1 
ATOM   7923  C  CA    . GLN D 2 114 ? 98.757  102.585 134.686 1.00 92.14  ? 114  GLN B CA    1 
ATOM   7924  C  C     . GLN D 2 114 ? 97.407  103.028 134.153 1.00 88.82  ? 114  GLN B C     1 
ATOM   7925  O  O     . GLN D 2 114 ? 96.389  102.891 134.834 1.00 88.02  ? 114  GLN B O     1 
ATOM   7926  C  CB    . GLN D 2 114 ? 99.691  103.802 134.794 1.00 95.48  ? 114  GLN B CB    1 
ATOM   7927  C  CG    . GLN D 2 114 ? 100.890 103.599 135.715 1.00 96.42  ? 114  GLN B CG    1 
ATOM   7928  C  CD    . GLN D 2 114 ? 100.589 103.976 137.155 1.00 101.14 ? 114  GLN B CD    1 
ATOM   7929  O  OE1   . GLN D 2 114 ? 99.467  103.789 137.643 1.00 99.50  ? 114  GLN B OE1   1 
ATOM   7930  N  NE2   . GLN D 2 114 ? 101.596 104.502 137.850 1.00 101.28 ? 114  GLN B NE2   1 
ATOM   7931  N  N     . ILE D 2 115 ? 97.390  103.544 132.928 1.00 82.83  ? 115  ILE B N     1 
ATOM   7932  C  CA    . ILE D 2 115 ? 96.133  104.013 132.380 1.00 82.01  ? 115  ILE B CA    1 
ATOM   7933  C  C     . ILE D 2 115 ? 95.106  102.886 132.246 1.00 80.39  ? 115  ILE B C     1 
ATOM   7934  O  O     . ILE D 2 115 ? 93.906  103.123 132.308 1.00 79.73  ? 115  ILE B O     1 
ATOM   7935  C  CB    . ILE D 2 115 ? 96.350  104.820 131.048 1.00 76.97  ? 115  ILE B CB    1 
ATOM   7936  C  CG1   . ILE D 2 115 ? 95.589  104.193 129.882 1.00 81.13  ? 115  ILE B CG1   1 
ATOM   7937  C  CG2   . ILE D 2 115 ? 97.828  104.977 130.786 1.00 70.60  ? 115  ILE B CG2   1 
ATOM   7938  C  CD1   . ILE D 2 115 ? 96.144  102.868 129.386 1.00 96.38  ? 115  ILE B CD1   1 
ATOM   7939  N  N     . ARG D 2 116 ? 95.575  101.654 132.114 1.00 84.18  ? 116  ARG B N     1 
ATOM   7940  C  CA    . ARG D 2 116 ? 94.672  100.521 132.000 1.00 87.48  ? 116  ARG B CA    1 
ATOM   7941  C  C     . ARG D 2 116 ? 94.043  100.309 133.377 1.00 94.01  ? 116  ARG B C     1 
ATOM   7942  O  O     . ARG D 2 116 ? 92.883  99.916  133.487 1.00 98.49  ? 116  ARG B O     1 
ATOM   7943  C  CB    . ARG D 2 116 ? 95.459  99.279  131.571 1.00 85.27  ? 116  ARG B CB    1 
ATOM   7944  C  CG    . ARG D 2 116 ? 94.681  98.275  130.736 1.00 89.87  ? 116  ARG B CG    1 
ATOM   7945  C  CD    . ARG D 2 116 ? 93.662  97.497  131.561 1.00 100.26 ? 116  ARG B CD    1 
ATOM   7946  N  NE    . ARG D 2 116 ? 94.288  96.534  132.469 1.00 102.83 ? 116  ARG B NE    1 
ATOM   7947  C  CZ    . ARG D 2 116 ? 94.841  95.381  132.095 1.00 98.77  ? 116  ARG B CZ    1 
ATOM   7948  N  NH1   . ARG D 2 116 ? 94.851  95.025  130.818 1.00 97.74  ? 116  ARG B NH1   1 
ATOM   7949  N  NH2   . ARG D 2 116 ? 95.398  94.586  133.000 1.00 90.09  ? 116  ARG B NH2   1 
ATOM   7950  N  N     . LYS D 2 117 ? 94.817  100.584 134.426 1.00 97.67  ? 117  LYS B N     1 
ATOM   7951  C  CA    . LYS D 2 117 ? 94.351  100.427 135.805 1.00 100.50 ? 117  LYS B CA    1 
ATOM   7952  C  C     . LYS D 2 117 ? 93.337  101.517 136.165 1.00 101.58 ? 117  LYS B C     1 
ATOM   7953  O  O     . LYS D 2 117 ? 92.389  101.281 136.912 1.00 101.70 ? 117  LYS B O     1 
ATOM   7954  C  CB    . LYS D 2 117 ? 95.548  100.496 136.769 1.00 102.58 ? 117  LYS B CB    1 
ATOM   7955  C  CG    . LYS D 2 117 ? 95.289  99.954  138.190 1.00 107.65 ? 117  LYS B CG    1 
ATOM   7956  C  CD    . LYS D 2 117 ? 94.599  100.959 139.126 1.00 109.38 ? 117  LYS B CD    1 
ATOM   7957  C  CE    . LYS D 2 117 ? 95.594  101.773 139.956 1.00 107.27 ? 117  LYS B CE    1 
ATOM   7958  N  NZ    . LYS D 2 117 ? 96.489  102.622 139.122 1.00 109.57 ? 117  LYS B NZ    1 
ATOM   7959  N  N     . GLU D 2 118 ? 93.541  102.707 135.610 1.00 103.51 ? 118  GLU B N     1 
ATOM   7960  C  CA    . GLU D 2 118 ? 92.684  103.862 135.872 1.00 104.38 ? 118  GLU B CA    1 
ATOM   7961  C  C     . GLU D 2 118 ? 91.392  103.878 135.056 1.00 104.05 ? 118  GLU B C     1 
ATOM   7962  O  O     . GLU D 2 118 ? 90.350  104.302 135.552 1.00 104.61 ? 118  GLU B O     1 
ATOM   7963  C  CB    . GLU D 2 118 ? 93.449  105.163 135.581 1.00 107.66 ? 118  GLU B CB    1 
ATOM   7964  C  CG    . GLU D 2 118 ? 94.952  105.113 135.864 1.00 117.15 ? 118  GLU B CG    1 
ATOM   7965  C  CD    . GLU D 2 118 ? 95.362  105.875 137.113 1.00 123.12 ? 118  GLU B CD    1 
ATOM   7966  O  OE1   . GLU D 2 118 ? 96.569  105.845 137.457 1.00 120.87 ? 118  GLU B OE1   1 
ATOM   7967  O  OE2   . GLU D 2 118 ? 94.484  106.506 137.744 1.00 125.81 ? 118  GLU B OE2   1 
ATOM   7968  N  N     . LYS D 2 119 ? 91.464  103.442 133.800 1.00 103.09 ? 119  LYS B N     1 
ATOM   7969  C  CA    . LYS D 2 119 ? 90.287  103.437 132.931 1.00 100.06 ? 119  LYS B CA    1 
ATOM   7970  C  C     . LYS D 2 119 ? 90.002  102.098 132.249 1.00 98.01  ? 119  LYS B C     1 
ATOM   7971  O  O     . LYS D 2 119 ? 89.081  101.996 131.440 1.00 98.22  ? 119  LYS B O     1 
ATOM   7972  C  CB    . LYS D 2 119 ? 90.408  104.530 131.862 1.00 96.63  ? 119  LYS B CB    1 
ATOM   7973  C  CG    . LYS D 2 119 ? 91.757  105.215 131.824 1.00 93.93  ? 119  LYS B CG    1 
ATOM   7974  C  CD    . LYS D 2 119 ? 91.840  106.320 132.855 1.00 95.96  ? 119  LYS B CD    1 
ATOM   7975  C  CE    . LYS D 2 119 ? 91.132  107.577 132.372 1.00 95.18  ? 119  LYS B CE    1 
ATOM   7976  N  NZ    . LYS D 2 119 ? 91.809  108.176 131.184 1.00 92.38  ? 119  LYS B NZ    1 
ATOM   7977  N  N     . GLY D 2 120 ? 90.795  101.079 132.567 1.00 97.47  ? 120  GLY B N     1 
ATOM   7978  C  CA    . GLY D 2 120 ? 90.590  99.761  131.983 1.00 95.32  ? 120  GLY B CA    1 
ATOM   7979  C  C     . GLY D 2 120 ? 90.758  99.665  130.477 1.00 93.20  ? 120  GLY B C     1 
ATOM   7980  O  O     . GLY D 2 120 ? 89.887  99.136  129.786 1.00 92.85  ? 120  GLY B O     1 
ATOM   7981  N  N     . GLY D 2 121 ? 91.884  100.159 129.972 1.00 92.01  ? 121  GLY B N     1 
ATOM   7982  C  CA    . GLY D 2 121 ? 92.146  100.125 128.542 1.00 88.88  ? 121  GLY B CA    1 
ATOM   7983  C  C     . GLY D 2 121 ? 92.690  101.471 128.109 1.00 87.64  ? 121  GLY B C     1 
ATOM   7984  O  O     . GLY D 2 121 ? 92.460  102.467 128.792 1.00 89.92  ? 121  GLY B O     1 
ATOM   7985  N  N     . TYR D 2 122 ? 93.406  101.522 126.989 1.00 83.49  ? 122  TYR B N     1 
ATOM   7986  C  CA    . TYR D 2 122 ? 93.964  102.792 126.524 1.00 80.45  ? 122  TYR B CA    1 
ATOM   7987  C  C     . TYR D 2 122 ? 92.861  103.793 126.179 1.00 81.88  ? 122  TYR B C     1 
ATOM   7988  O  O     . TYR D 2 122 ? 91.838  103.431 125.591 1.00 78.53  ? 122  TYR B O     1 
ATOM   7989  C  CB    . TYR D 2 122 ? 94.854  102.579 125.303 1.00 77.38  ? 122  TYR B CB    1 
ATOM   7990  C  CG    . TYR D 2 122 ? 95.666  103.794 124.928 1.00 74.84  ? 122  TYR B CG    1 
ATOM   7991  C  CD1   . TYR D 2 122 ? 96.641  104.295 125.788 1.00 75.42  ? 122  TYR B CD1   1 
ATOM   7992  C  CD2   . TYR D 2 122 ? 95.488  104.424 123.699 1.00 79.72  ? 122  TYR B CD2   1 
ATOM   7993  C  CE1   . TYR D 2 122 ? 97.426  105.395 125.428 1.00 75.24  ? 122  TYR B CE1   1 
ATOM   7994  C  CE2   . TYR D 2 122 ? 96.265  105.523 123.329 1.00 76.12  ? 122  TYR B CE2   1 
ATOM   7995  C  CZ    . TYR D 2 122 ? 97.231  106.000 124.197 1.00 75.10  ? 122  TYR B CZ    1 
ATOM   7996  O  OH    . TYR D 2 122 ? 98.004  107.074 123.828 1.00 75.06  ? 122  TYR B OH    1 
ATOM   7997  N  N     . ASP D 2 123 ? 93.084  105.054 126.549 1.00 82.85  ? 123  ASP B N     1 
ATOM   7998  C  CA    . ASP D 2 123 ? 92.124  106.127 126.312 1.00 75.59  ? 123  ASP B CA    1 
ATOM   7999  C  C     . ASP D 2 123 ? 92.382  106.922 125.039 1.00 77.19  ? 123  ASP B C     1 
ATOM   8000  O  O     . ASP D 2 123 ? 91.746  107.944 124.813 1.00 79.85  ? 123  ASP B O     1 
ATOM   8001  C  CB    . ASP D 2 123 ? 92.117  107.083 127.502 1.00 75.70  ? 123  ASP B CB    1 
ATOM   8002  C  CG    . ASP D 2 123 ? 93.519  107.457 127.966 1.00 81.13  ? 123  ASP B CG    1 
ATOM   8003  O  OD1   . ASP D 2 123 ? 94.322  107.976 127.153 1.00 77.80  ? 123  ASP B OD1   1 
ATOM   8004  O  OD2   . ASP D 2 123 ? 93.815  107.232 129.159 1.00 86.08  ? 123  ASP B OD2   1 
ATOM   8005  N  N     . GLY D 2 124 ? 93.316  106.462 124.214 1.00 76.29  ? 124  GLY B N     1 
ATOM   8006  C  CA    . GLY D 2 124 ? 93.611  107.162 122.976 1.00 76.19  ? 124  GLY B CA    1 
ATOM   8007  C  C     . GLY D 2 124 ? 94.146  108.562 123.192 1.00 74.79  ? 124  GLY B C     1 
ATOM   8008  O  O     . GLY D 2 124 ? 94.014  109.432 122.330 1.00 68.82  ? 124  GLY B O     1 
ATOM   8009  N  N     . ARG D 2 125 ? 94.775  108.782 124.337 1.00 75.19  ? 125  ARG B N     1 
ATOM   8010  C  CA    . ARG D 2 125 ? 95.293  110.103 124.634 1.00 79.90  ? 125  ARG B CA    1 
ATOM   8011  C  C     . ARG D 2 125 ? 96.297  110.624 123.623 1.00 80.91  ? 125  ARG B C     1 
ATOM   8012  O  O     . ARG D 2 125 ? 96.415  111.832 123.448 1.00 83.37  ? 125  ARG B O     1 
ATOM   8013  C  CB    . ARG D 2 125 ? 95.905  110.137 126.031 1.00 81.40  ? 125  ARG B CB    1 
ATOM   8014  C  CG    . ARG D 2 125 ? 97.037  109.162 126.259 1.00 89.88  ? 125  ARG B CG    1 
ATOM   8015  C  CD    . ARG D 2 125 ? 97.455  109.221 127.707 1.00 84.44  ? 125  ARG B CD    1 
ATOM   8016  N  NE    . ARG D 2 125 ? 96.285  109.179 128.577 1.00 84.81  ? 125  ARG B NE    1 
ATOM   8017  C  CZ    . ARG D 2 125 ? 96.332  109.332 129.896 1.00 91.12  ? 125  ARG B CZ    1 
ATOM   8018  N  NH1   . ARG D 2 125 ? 97.497  109.534 130.500 1.00 87.38  ? 125  ARG B NH1   1 
ATOM   8019  N  NH2   . ARG D 2 125 ? 95.214  109.292 130.611 1.00 91.05  ? 125  ARG B NH2   1 
ATOM   8020  N  N     . ALA D 2 126 ? 97.007  109.727 122.945 1.00 79.71  ? 126  ALA B N     1 
ATOM   8021  C  CA    . ALA D 2 126 ? 98.007  110.151 121.973 1.00 73.10  ? 126  ALA B CA    1 
ATOM   8022  C  C     . ALA D 2 126 ? 97.395  110.745 120.707 1.00 73.47  ? 126  ALA B C     1 
ATOM   8023  O  O     . ALA D 2 126 ? 98.101  111.323 119.878 1.00 77.57  ? 126  ALA B O     1 
ATOM   8024  C  CB    . ALA D 2 126 ? 98.910  108.984 121.625 1.00 82.65  ? 126  ALA B CB    1 
ATOM   8025  N  N     . ARG D 2 127 ? 96.086  110.605 120.551 1.00 68.84  ? 127  ARG B N     1 
ATOM   8026  C  CA    . ARG D 2 127 ? 95.427  111.152 119.375 1.00 77.82  ? 127  ARG B CA    1 
ATOM   8027  C  C     . ARG D 2 127 ? 95.607  112.674 119.332 1.00 87.91  ? 127  ARG B C     1 
ATOM   8028  O  O     . ARG D 2 127 ? 95.651  113.293 118.265 1.00 91.43  ? 127  ARG B O     1 
ATOM   8029  C  CB    . ARG D 2 127 ? 93.935  110.837 119.414 1.00 73.35  ? 127  ARG B CB    1 
ATOM   8030  C  CG    . ARG D 2 127 ? 93.547  109.374 119.244 1.00 74.09  ? 127  ARG B CG    1 
ATOM   8031  C  CD    . ARG D 2 127 ? 92.074  109.319 118.831 1.00 68.93  ? 127  ARG B CD    1 
ATOM   8032  N  NE    . ARG D 2 127 ? 91.600  107.989 118.459 1.00 67.75  ? 127  ARG B NE    1 
ATOM   8033  C  CZ    . ARG D 2 127 ? 90.432  107.752 117.860 1.00 67.23  ? 127  ARG B CZ    1 
ATOM   8034  N  NH1   . ARG D 2 127 ? 89.616  108.755 117.557 1.00 46.94  ? 127  ARG B NH1   1 
ATOM   8035  N  NH2   . ARG D 2 127 ? 90.071  106.505 117.575 1.00 65.84  ? 127  ARG B NH2   1 
ATOM   8036  N  N     . ASN D 2 128 ? 95.726  113.267 120.512 1.00 95.16  ? 128  ASN B N     1 
ATOM   8037  C  CA    . ASN D 2 128 ? 95.856  114.708 120.642 1.00 98.47  ? 128  ASN B CA    1 
ATOM   8038  C  C     . ASN D 2 128 ? 97.268  115.257 120.468 1.00 98.37  ? 128  ASN B C     1 
ATOM   8039  O  O     . ASN D 2 128 ? 97.493  116.457 120.599 1.00 103.46 ? 128  ASN B O     1 
ATOM   8040  C  CB    . ASN D 2 128 ? 95.275  115.119 121.988 1.00 105.25 ? 128  ASN B CB    1 
ATOM   8041  C  CG    . ASN D 2 128 ? 93.918  114.479 122.242 1.00 108.72 ? 128  ASN B CG    1 
ATOM   8042  O  OD1   . ASN D 2 128 ? 92.952  114.739 121.520 1.00 108.97 ? 128  ASN B OD1   1 
ATOM   8043  N  ND2   . ASN D 2 128 ? 93.845  113.625 123.262 1.00 106.95 ? 128  ASN B ND2   1 
ATOM   8044  N  N     . ILE D 2 129 ? 98.222  114.384 120.179 1.00 95.14  ? 129  ILE B N     1 
ATOM   8045  C  CA    . ILE D 2 129 ? 99.583  114.833 119.957 1.00 95.24  ? 129  ILE B CA    1 
ATOM   8046  C  C     . ILE D 2 129 ? 99.599  115.444 118.555 1.00 99.29  ? 129  ILE B C     1 
ATOM   8047  O  O     . ILE D 2 129 ? 99.092  114.844 117.607 1.00 100.48 ? 129  ILE B O     1 
ATOM   8048  C  CB    . ILE D 2 129 ? 100.570 113.648 120.034 1.00 94.40  ? 129  ILE B CB    1 
ATOM   8049  C  CG1   . ILE D 2 129 ? 100.486 113.004 121.423 1.00 95.69  ? 129  ILE B CG1   1 
ATOM   8050  C  CG2   . ILE D 2 129 ? 101.991 114.118 119.733 1.00 89.22  ? 129  ILE B CG2   1 
ATOM   8051  C  CD1   . ILE D 2 129 ? 101.402 111.804 121.614 1.00 95.21  ? 129  ILE B CD1   1 
ATOM   8052  N  N     . PRO D 2 130 ? 100.149 116.663 118.412 1.00 103.91 ? 130  PRO B N     1 
ATOM   8053  C  CA    . PRO D 2 130 ? 100.209 117.324 117.099 1.00 102.93 ? 130  PRO B CA    1 
ATOM   8054  C  C     . PRO D 2 130 ? 100.916 116.436 116.075 1.00 100.81 ? 130  PRO B C     1 
ATOM   8055  O  O     . PRO D 2 130 ? 102.032 115.960 116.316 1.00 95.69  ? 130  PRO B O     1 
ATOM   8056  C  CB    . PRO D 2 130 ? 100.996 118.602 117.393 1.00 102.74 ? 130  PRO B CB    1 
ATOM   8057  C  CG    . PRO D 2 130 ? 100.618 118.909 118.819 1.00 102.67 ? 130  PRO B CG    1 
ATOM   8058  C  CD    . PRO D 2 130 ? 100.683 117.543 119.470 1.00 104.38 ? 130  PRO B CD    1 
ATOM   8059  N  N     . PRO D 2 131 ? 100.268 116.193 114.923 1.00 99.20  ? 131  PRO B N     1 
ATOM   8060  C  CA    . PRO D 2 131 ? 100.828 115.357 113.854 1.00 98.76  ? 131  PRO B CA    1 
ATOM   8061  C  C     . PRO D 2 131 ? 102.294 115.671 113.565 1.00 101.73 ? 131  PRO B C     1 
ATOM   8062  O  O     . PRO D 2 131 ? 103.138 114.770 113.530 1.00 102.87 ? 131  PRO B O     1 
ATOM   8063  C  CB    . PRO D 2 131 ? 99.916  115.665 112.672 1.00 96.68  ? 131  PRO B CB    1 
ATOM   8064  C  CG    . PRO D 2 131 ? 98.583  115.850 113.345 1.00 95.92  ? 131  PRO B CG    1 
ATOM   8065  C  CD    . PRO D 2 131 ? 98.935  116.705 114.551 1.00 95.61  ? 131  PRO B CD    1 
ATOM   8066  N  N     . GLU D 2 132 ? 102.594 116.951 113.366 1.00 102.76 ? 132  GLU B N     1 
ATOM   8067  C  CA    . GLU D 2 132 ? 103.962 117.369 113.083 1.00 104.67 ? 132  GLU B CA    1 
ATOM   8068  C  C     . GLU D 2 132 ? 104.905 117.059 114.239 1.00 106.41 ? 132  GLU B C     1 
ATOM   8069  O  O     . GLU D 2 132 ? 106.075 116.727 114.027 1.00 106.50 ? 132  GLU B O     1 
ATOM   8070  C  CB    . GLU D 2 132 ? 103.999 118.859 112.759 1.00 106.02 ? 132  GLU B CB    1 
ATOM   8071  C  CG    . GLU D 2 132 ? 103.445 119.175 111.384 1.00 111.83 ? 132  GLU B CG    1 
ATOM   8072  C  CD    . GLU D 2 132 ? 104.036 118.268 110.318 1.00 115.62 ? 132  GLU B CD    1 
ATOM   8073  O  OE1   . GLU D 2 132 ? 105.280 118.137 110.274 1.00 115.08 ? 132  GLU B OE1   1 
ATOM   8074  O  OE2   . GLU D 2 132 ? 103.260 117.686 109.528 1.00 119.42 ? 132  GLU B OE2   1 
ATOM   8075  N  N     . GLU D 2 133 ? 104.389 117.168 115.460 1.00 105.91 ? 133  GLU B N     1 
ATOM   8076  C  CA    . GLU D 2 133 ? 105.170 116.878 116.657 1.00 105.51 ? 133  GLU B CA    1 
ATOM   8077  C  C     . GLU D 2 133 ? 105.471 115.387 116.717 1.00 106.76 ? 133  GLU B C     1 
ATOM   8078  O  O     . GLU D 2 133 ? 106.598 114.964 116.999 1.00 107.53 ? 133  GLU B O     1 
ATOM   8079  C  CB    . GLU D 2 133 ? 104.389 117.290 117.909 1.00 105.72 ? 133  GLU B CB    1 
ATOM   8080  C  CG    . GLU D 2 133 ? 104.827 116.569 119.186 1.00 106.42 ? 133  GLU B CG    1 
ATOM   8081  C  CD    . GLU D 2 133 ? 104.188 117.140 120.443 1.00 106.96 ? 133  GLU B CD    1 
ATOM   8082  O  OE1   . GLU D 2 133 ? 104.262 116.463 121.493 1.00 105.34 ? 133  GLU B OE1   1 
ATOM   8083  O  OE2   . GLU D 2 133 ? 103.626 118.260 120.385 1.00 97.47  ? 133  GLU B OE2   1 
ATOM   8084  N  N     . ALA D 2 134 ? 104.442 114.591 116.458 1.00 103.66 ? 134  ALA B N     1 
ATOM   8085  C  CA    . ALA D 2 134 ? 104.590 113.151 116.479 1.00 97.02  ? 134  ALA B CA    1 
ATOM   8086  C  C     . ALA D 2 134 ? 105.687 112.761 115.507 1.00 92.16  ? 134  ALA B C     1 
ATOM   8087  O  O     . ALA D 2 134 ? 106.609 112.027 115.862 1.00 86.41  ? 134  ALA B O     1 
ATOM   8088  C  CB    . ALA D 2 134 ? 103.283 112.497 116.085 1.00 100.20 ? 134  ALA B CB    1 
ATOM   8089  N  N     . GLU D 2 135 ? 105.588 113.277 114.284 1.00 90.93  ? 135  GLU B N     1 
ATOM   8090  C  CA    . GLU D 2 135 ? 106.558 112.971 113.239 1.00 94.00  ? 135  GLU B CA    1 
ATOM   8091  C  C     . GLU D 2 135 ? 107.967 113.354 113.651 1.00 95.39  ? 135  GLU B C     1 
ATOM   8092  O  O     . GLU D 2 135 ? 108.923 112.618 113.401 1.00 88.46  ? 135  GLU B O     1 
ATOM   8093  C  CB    . GLU D 2 135 ? 106.184 113.686 111.938 1.00 97.83  ? 135  GLU B CB    1 
ATOM   8094  C  CG    . GLU D 2 135 ? 104.790 113.347 111.421 1.00 102.44 ? 135  GLU B CG    1 
ATOM   8095  C  CD    . GLU D 2 135 ? 104.549 111.846 111.318 1.00 108.56 ? 135  GLU B CD    1 
ATOM   8096  O  OE1   . GLU D 2 135 ? 105.307 111.166 110.592 1.00 112.12 ? 135  GLU B OE1   1 
ATOM   8097  O  OE2   . GLU D 2 135 ? 103.601 111.343 111.963 1.00 105.01 ? 135  GLU B OE2   1 
ATOM   8098  N  N     . GLU D 2 136 ? 108.090 114.510 114.288 1.00 99.74  ? 136  GLU B N     1 
ATOM   8099  C  CA    . GLU D 2 136 ? 109.387 114.979 114.733 1.00 103.60 ? 136  GLU B CA    1 
ATOM   8100  C  C     . GLU D 2 136 ? 109.938 114.026 115.789 1.00 103.87 ? 136  GLU B C     1 
ATOM   8101  O  O     . GLU D 2 136 ? 111.095 113.610 115.719 1.00 108.11 ? 136  GLU B O     1 
ATOM   8102  C  CB    . GLU D 2 136 ? 109.265 116.399 115.301 1.00 108.00 ? 136  GLU B CB    1 
ATOM   8103  C  CG    . GLU D 2 136 ? 108.917 117.468 114.265 1.00 112.31 ? 136  GLU B CG    1 
ATOM   8104  C  CD    . GLU D 2 136 ? 110.077 117.800 113.328 1.00 117.22 ? 136  GLU B CD    1 
ATOM   8105  O  OE1   . GLU D 2 136 ? 109.863 118.571 112.363 1.00 117.55 ? 136  GLU B OE1   1 
ATOM   8106  O  OE2   . GLU D 2 136 ? 111.203 117.299 113.559 1.00 112.38 ? 136  GLU B OE2   1 
ATOM   8107  N  N     . ARG D 2 137 ? 109.102 113.671 116.760 1.00 100.09 ? 137  ARG B N     1 
ATOM   8108  C  CA    . ARG D 2 137 ? 109.524 112.780 117.831 1.00 97.14  ? 137  ARG B CA    1 
ATOM   8109  C  C     . ARG D 2 137 ? 109.961 111.426 117.281 1.00 99.67  ? 137  ARG B C     1 
ATOM   8110  O  O     . ARG D 2 137 ? 110.790 110.731 117.881 1.00 95.49  ? 137  ARG B O     1 
ATOM   8111  C  CB    . ARG D 2 137 ? 108.386 112.628 118.839 1.00 92.35  ? 137  ARG B CB    1 
ATOM   8112  C  CG    . ARG D 2 137 ? 107.961 113.961 119.448 1.00 89.86  ? 137  ARG B CG    1 
ATOM   8113  C  CD    . ARG D 2 137 ? 106.795 113.831 120.412 1.00 89.11  ? 137  ARG B CD    1 
ATOM   8114  N  NE    . ARG D 2 137 ? 107.093 112.945 121.536 1.00 80.59  ? 137  ARG B NE    1 
ATOM   8115  C  CZ    . ARG D 2 137 ? 106.233 112.658 122.513 1.00 82.72  ? 137  ARG B CZ    1 
ATOM   8116  N  NH1   . ARG D 2 137 ? 105.013 113.193 122.510 1.00 71.77  ? 137  ARG B NH1   1 
ATOM   8117  N  NH2   . ARG D 2 137 ? 106.591 111.831 123.492 1.00 71.82  ? 137  ARG B NH2   1 
ATOM   8118  N  N     . ALA D 2 138 ? 109.413 111.067 116.124 1.00 101.99 ? 138  ALA B N     1 
ATOM   8119  C  CA    . ALA D 2 138 ? 109.751 109.804 115.479 1.00 105.86 ? 138  ALA B CA    1 
ATOM   8120  C  C     . ALA D 2 138 ? 111.117 109.917 114.813 1.00 109.04 ? 138  ALA B C     1 
ATOM   8121  O  O     . ALA D 2 138 ? 111.953 109.021 114.941 1.00 113.48 ? 138  ALA B O     1 
ATOM   8122  C  CB    . ALA D 2 138 ? 108.700 109.441 114.445 1.00 104.66 ? 138  ALA B CB    1 
ATOM   8123  N  N     . ARG D 2 139 ? 111.339 111.018 114.099 1.00 109.66 ? 139  ARG B N     1 
ATOM   8124  C  CA    . ARG D 2 139 ? 112.612 111.243 113.418 1.00 108.86 ? 139  ARG B CA    1 
ATOM   8125  C  C     . ARG D 2 139 ? 113.775 111.243 114.411 1.00 106.21 ? 139  ARG B C     1 
ATOM   8126  O  O     . ARG D 2 139 ? 114.876 110.793 114.086 1.00 100.14 ? 139  ARG B O     1 
ATOM   8127  C  CB    . ARG D 2 139 ? 112.565 112.567 112.638 1.00 110.38 ? 139  ARG B CB    1 
ATOM   8128  C  CG    . ARG D 2 139 ? 111.684 112.508 111.386 1.00 113.88 ? 139  ARG B CG    1 
ATOM   8129  C  CD    . ARG D 2 139 ? 111.133 113.878 110.989 1.00 115.10 ? 139  ARG B CD    1 
ATOM   8130  N  NE    . ARG D 2 139 ? 110.201 113.797 109.862 1.00 111.51 ? 139  ARG B NE    1 
ATOM   8131  C  CZ    . ARG D 2 139 ? 109.300 114.731 109.561 1.00 111.44 ? 139  ARG B CZ    1 
ATOM   8132  N  NH1   . ARG D 2 139 ? 109.199 115.830 110.302 1.00 106.65 ? 139  ARG B NH1   1 
ATOM   8133  N  NH2   . ARG D 2 139 ? 108.494 114.565 108.518 1.00 110.77 ? 139  ARG B NH2   1 
ATOM   8134  N  N     . ARG D 2 140 ? 113.521 111.734 115.624 1.00 107.11 ? 140  ARG B N     1 
ATOM   8135  C  CA    . ARG D 2 140 ? 114.546 111.776 116.664 1.00 108.43 ? 140  ARG B CA    1 
ATOM   8136  C  C     . ARG D 2 140 ? 114.844 110.388 117.217 1.00 106.81 ? 140  ARG B C     1 
ATOM   8137  O  O     . ARG D 2 140 ? 115.764 110.204 118.017 1.00 101.93 ? 140  ARG B O     1 
ATOM   8138  C  CB    . ARG D 2 140 ? 114.124 112.708 117.808 1.00 113.14 ? 140  ARG B CB    1 
ATOM   8139  C  CG    . ARG D 2 140 ? 114.350 114.193 117.521 1.00 118.09 ? 140  ARG B CG    1 
ATOM   8140  C  CD    . ARG D 2 140 ? 115.735 114.424 116.915 1.00 121.46 ? 140  ARG B CD    1 
ATOM   8141  N  NE    . ARG D 2 140 ? 116.784 113.703 117.637 1.00 121.45 ? 140  ARG B NE    1 
ATOM   8142  C  CZ    . ARG D 2 140 ? 118.017 113.512 117.175 1.00 118.76 ? 140  ARG B CZ    1 
ATOM   8143  N  NH1   . ARG D 2 140 ? 118.367 113.986 115.985 1.00 116.07 ? 140  ARG B NH1   1 
ATOM   8144  N  NH2   . ARG D 2 140 ? 118.901 112.845 117.904 1.00 114.00 ? 140  ARG B NH2   1 
ATOM   8145  N  N     . GLY D 2 141 ? 114.054 109.411 116.789 1.00 106.23 ? 141  GLY B N     1 
ATOM   8146  C  CA    . GLY D 2 141 ? 114.263 108.050 117.237 1.00 102.79 ? 141  GLY B CA    1 
ATOM   8147  C  C     . GLY D 2 141 ? 113.525 107.673 118.503 1.00 102.47 ? 141  GLY B C     1 
ATOM   8148  O  O     . GLY D 2 141 ? 113.754 106.592 119.042 1.00 101.75 ? 141  GLY B O     1 
ATOM   8149  N  N     . GLU D 2 142 ? 112.644 108.542 118.989 1.00 99.82  ? 142  GLU B N     1 
ATOM   8150  C  CA    . GLU D 2 142 ? 111.906 108.218 120.203 1.00 100.97 ? 142  GLU B CA    1 
ATOM   8151  C  C     . GLU D 2 142 ? 111.057 106.968 119.982 1.00 100.82 ? 142  GLU B C     1 
ATOM   8152  O  O     . GLU D 2 142 ? 110.283 106.893 119.028 1.00 102.48 ? 142  GLU B O     1 
ATOM   8153  C  CB    . GLU D 2 142 ? 111.007 109.380 120.622 1.00 99.19  ? 142  GLU B CB    1 
ATOM   8154  C  CG    . GLU D 2 142 ? 110.108 109.037 121.798 1.00 97.58  ? 142  GLU B CG    1 
ATOM   8155  C  CD    . GLU D 2 142 ? 109.176 110.171 122.164 1.00 102.55 ? 142  GLU B CD    1 
ATOM   8156  O  OE1   . GLU D 2 142 ? 108.803 110.947 121.260 1.00 100.63 ? 142  GLU B OE1   1 
ATOM   8157  O  OE2   . GLU D 2 142 ? 108.803 110.282 123.351 1.00 105.28 ? 142  GLU B OE2   1 
ATOM   8158  N  N     . PRO D 2 143 ? 111.196 105.966 120.867 1.00 100.29 ? 143  PRO B N     1 
ATOM   8159  C  CA    . PRO D 2 143 ? 110.439 104.710 120.768 1.00 99.68  ? 143  PRO B CA    1 
ATOM   8160  C  C     . PRO D 2 143 ? 108.930 104.961 120.732 1.00 95.35  ? 143  PRO B C     1 
ATOM   8161  O  O     . PRO D 2 143 ? 108.424 105.818 121.463 1.00 95.40  ? 143  PRO B O     1 
ATOM   8162  C  CB    . PRO D 2 143 ? 110.853 103.953 122.035 1.00 99.50  ? 143  PRO B CB    1 
ATOM   8163  C  CG    . PRO D 2 143 ? 112.227 104.476 122.319 1.00 101.44 ? 143  PRO B CG    1 
ATOM   8164  C  CD    . PRO D 2 143 ? 112.072 105.957 122.053 1.00 100.64 ? 143  PRO B CD    1 
ATOM   8165  N  N     . HIS D 2 144 ? 108.213 104.210 119.899 1.00 89.13  ? 144  HIS B N     1 
ATOM   8166  C  CA    . HIS D 2 144 ? 106.767 104.378 119.803 1.00 81.78  ? 144  HIS B CA    1 
ATOM   8167  C  C     . HIS D 2 144 ? 106.070 103.253 119.033 1.00 78.71  ? 144  HIS B C     1 
ATOM   8168  O  O     . HIS D 2 144 ? 106.723 102.366 118.478 1.00 76.25  ? 144  HIS B O     1 
ATOM   8169  C  CB    . HIS D 2 144 ? 106.454 105.724 119.142 1.00 77.79  ? 144  HIS B CB    1 
ATOM   8170  C  CG    . HIS D 2 144 ? 106.894 105.815 117.714 1.00 76.17  ? 144  HIS B CG    1 
ATOM   8171  N  ND1   . HIS D 2 144 ? 108.162 105.468 117.302 1.00 71.96  ? 144  HIS B ND1   1 
ATOM   8172  C  CD2   . HIS D 2 144 ? 106.236 106.227 116.604 1.00 80.46  ? 144  HIS B CD2   1 
ATOM   8173  C  CE1   . HIS D 2 144 ? 108.269 105.662 115.999 1.00 74.78  ? 144  HIS B CE1   1 
ATOM   8174  N  NE2   . HIS D 2 144 ? 107.114 106.123 115.551 1.00 81.03  ? 144  HIS B NE2   1 
ATOM   8175  N  N     . VAL D 2 145 ? 104.737 103.289 119.034 1.00 71.83  ? 145  VAL B N     1 
ATOM   8176  C  CA    . VAL D 2 145 ? 103.927 102.316 118.304 1.00 66.16  ? 145  VAL B CA    1 
ATOM   8177  C  C     . VAL D 2 145 ? 102.915 103.095 117.490 1.00 57.41  ? 145  VAL B C     1 
ATOM   8178  O  O     . VAL D 2 145 ? 102.655 104.252 117.775 1.00 55.95  ? 145  VAL B O     1 
ATOM   8179  C  CB    . VAL D 2 145 ? 103.125 101.363 119.226 1.00 64.74  ? 145  VAL B CB    1 
ATOM   8180  C  CG1   . VAL D 2 145 ? 104.055 100.643 120.176 1.00 72.50  ? 145  VAL B CG1   1 
ATOM   8181  C  CG2   . VAL D 2 145 ? 102.045 102.131 119.960 1.00 63.99  ? 145  VAL B CG2   1 
ATOM   8182  N  N     . ILE D 2 146 ? 102.364 102.462 116.462 1.00 56.79  ? 146  ILE B N     1 
ATOM   8183  C  CA    . ILE D 2 146 ? 101.343 103.093 115.626 1.00 53.75  ? 146  ILE B CA    1 
ATOM   8184  C  C     . ILE D 2 146 ? 100.022 102.376 115.942 1.00 51.76  ? 146  ILE B C     1 
ATOM   8185  O  O     . ILE D 2 146 ? 99.962  101.142 115.957 1.00 47.84  ? 146  ILE B O     1 
ATOM   8186  C  CB    . ILE D 2 146 ? 101.661 102.958 114.109 1.00 56.00  ? 146  ILE B CB    1 
ATOM   8187  C  CG1   . ILE D 2 146 ? 102.898 103.798 113.766 1.00 52.70  ? 146  ILE B CG1   1 
ATOM   8188  C  CG2   . ILE D 2 146 ? 100.442 103.394 113.269 1.00 53.67  ? 146  ILE B CG2   1 
ATOM   8189  C  CD1   . ILE D 2 146 ? 103.182 103.904 112.278 1.00 53.39  ? 146  ILE B CD1   1 
ATOM   8190  N  N     . ARG D 2 147 ? 98.973  103.148 116.207 1.00 44.98  ? 147  ARG B N     1 
ATOM   8191  C  CA    . ARG D 2 147 ? 97.683  102.582 116.577 1.00 42.37  ? 147  ARG B CA    1 
ATOM   8192  C  C     . ARG D 2 147 ? 96.608  102.849 115.553 1.00 42.13  ? 147  ARG B C     1 
ATOM   8193  O  O     . ARG D 2 147 ? 96.670  103.833 114.815 1.00 46.30  ? 147  ARG B O     1 
ATOM   8194  C  CB    . ARG D 2 147 ? 97.212  103.149 117.934 1.00 38.60  ? 147  ARG B CB    1 
ATOM   8195  C  CG    . ARG D 2 147 ? 97.872  102.524 119.170 1.00 46.94  ? 147  ARG B CG    1 
ATOM   8196  C  CD    . ARG D 2 147 ? 97.499  103.249 120.476 1.00 51.15  ? 147  ARG B CD    1 
ATOM   8197  N  NE    . ARG D 2 147 ? 98.137  102.649 121.652 1.00 48.82  ? 147  ARG B NE    1 
ATOM   8198  C  CZ    . ARG D 2 147 ? 97.605  101.671 122.383 1.00 55.67  ? 147  ARG B CZ    1 
ATOM   8199  N  NH1   . ARG D 2 147 ? 96.412  101.178 122.077 1.00 54.61  ? 147  ARG B NH1   1 
ATOM   8200  N  NH2   . ARG D 2 147 ? 98.281  101.158 123.403 1.00 50.58  ? 147  ARG B NH2   1 
ATOM   8201  N  N     . LEU D 2 148 ? 95.620  101.959 115.503 1.00 42.95  ? 148  LEU B N     1 
ATOM   8202  C  CA    . LEU D 2 148 ? 94.495  102.151 114.602 1.00 38.68  ? 148  LEU B CA    1 
ATOM   8203  C  C     . LEU D 2 148 ? 93.747  103.318 115.193 1.00 42.82  ? 148  LEU B C     1 
ATOM   8204  O  O     . LEU D 2 148 ? 93.573  103.397 116.411 1.00 46.90  ? 148  LEU B O     1 
ATOM   8205  C  CB    . LEU D 2 148 ? 93.568  100.935 114.579 1.00 37.44  ? 148  LEU B CB    1 
ATOM   8206  C  CG    . LEU D 2 148 ? 92.308  101.038 113.700 1.00 38.22  ? 148  LEU B CG    1 
ATOM   8207  C  CD1   . LEU D 2 148 ? 92.622  101.383 112.262 1.00 33.82  ? 148  LEU B CD1   1 
ATOM   8208  C  CD2   . LEU D 2 148 ? 91.603  99.711  113.724 1.00 33.37  ? 148  LEU B CD2   1 
ATOM   8209  N  N     . LYS D 2 149 ? 93.334  104.237 114.338 1.00 43.94  ? 149  LYS B N     1 
ATOM   8210  C  CA    . LYS D 2 149 ? 92.593  105.392 114.789 1.00 48.79  ? 149  LYS B CA    1 
ATOM   8211  C  C     . LYS D 2 149 ? 91.130  105.131 114.547 1.00 40.57  ? 149  LYS B C     1 
ATOM   8212  O  O     . LYS D 2 149 ? 90.559  105.658 113.609 1.00 43.33  ? 149  LYS B O     1 
ATOM   8213  C  CB    . LYS D 2 149 ? 93.025  106.651 114.031 1.00 53.30  ? 149  LYS B CB    1 
ATOM   8214  C  CG    . LYS D 2 149 ? 92.390  107.925 114.582 1.00 62.00  ? 149  LYS B CG    1 
ATOM   8215  C  CD    . LYS D 2 149 ? 93.147  109.178 114.144 1.00 70.77  ? 149  LYS B CD    1 
ATOM   8216  C  CE    . LYS D 2 149 ? 92.660  110.435 114.892 1.00 75.51  ? 149  LYS B CE    1 
ATOM   8217  N  NZ    . LYS D 2 149 ? 93.388  111.694 114.488 1.00 65.66  ? 149  LYS B NZ    1 
ATOM   8218  N  N     . VAL D 2 150 ? 90.531  104.303 115.390 1.00 40.76  ? 150  VAL B N     1 
ATOM   8219  C  CA    . VAL D 2 150 ? 89.114  103.978 115.265 1.00 40.40  ? 150  VAL B CA    1 
ATOM   8220  C  C     . VAL D 2 150 ? 88.179  105.188 115.259 1.00 39.39  ? 150  VAL B C     1 
ATOM   8221  O  O     . VAL D 2 150 ? 88.242  106.036 116.147 1.00 43.45  ? 150  VAL B O     1 
ATOM   8222  C  CB    . VAL D 2 150 ? 88.664  103.037 116.414 1.00 41.37  ? 150  VAL B CB    1 
ATOM   8223  C  CG1   . VAL D 2 150 ? 87.141  102.779 116.327 1.00 24.67  ? 150  VAL B CG1   1 
ATOM   8224  C  CG2   . VAL D 2 150 ? 89.456  101.711 116.342 1.00 32.66  ? 150  VAL B CG2   1 
ATOM   8225  N  N     . PRO D 2 151 ? 87.292  105.273 114.256 1.00 44.28  ? 151  PRO B N     1 
ATOM   8226  C  CA    . PRO D 2 151 ? 86.306  106.353 114.084 1.00 48.51  ? 151  PRO B CA    1 
ATOM   8227  C  C     . PRO D 2 151 ? 85.355  106.394 115.271 1.00 51.35  ? 151  PRO B C     1 
ATOM   8228  O  O     . PRO D 2 151 ? 84.538  105.490 115.428 1.00 53.94  ? 151  PRO B O     1 
ATOM   8229  C  CB    . PRO D 2 151 ? 85.539  105.945 112.822 1.00 41.55  ? 151  PRO B CB    1 
ATOM   8230  C  CG    . PRO D 2 151 ? 86.535  105.167 112.059 1.00 46.79  ? 151  PRO B CG    1 
ATOM   8231  C  CD    . PRO D 2 151 ? 87.259  104.353 113.107 1.00 44.98  ? 151  PRO B CD    1 
ATOM   8232  N  N     . ARG D 2 152 ? 85.449  107.422 116.106 1.00 51.81  ? 152  ARG B N     1 
ATOM   8233  C  CA    . ARG D 2 152 ? 84.540  107.537 117.251 1.00 57.13  ? 152  ARG B CA    1 
ATOM   8234  C  C     . ARG D 2 152 ? 83.750  108.849 117.207 1.00 60.02  ? 152  ARG B C     1 
ATOM   8235  O  O     . ARG D 2 152 ? 84.318  109.926 116.991 1.00 60.75  ? 152  ARG B O     1 
ATOM   8236  C  CB    . ARG D 2 152 ? 85.310  107.474 118.569 1.00 60.80  ? 152  ARG B CB    1 
ATOM   8237  C  CG    . ARG D 2 152 ? 85.930  106.132 118.889 1.00 65.68  ? 152  ARG B CG    1 
ATOM   8238  C  CD    . ARG D 2 152 ? 86.678  106.176 120.233 1.00 69.28  ? 152  ARG B CD    1 
ATOM   8239  N  NE    . ARG D 2 152 ? 87.796  105.234 120.248 1.00 61.11  ? 152  ARG B NE    1 
ATOM   8240  C  CZ    . ARG D 2 152 ? 87.659  103.928 120.058 1.00 59.46  ? 152  ARG B CZ    1 
ATOM   8241  N  NH1   . ARG D 2 152 ? 86.448  103.415 119.854 1.00 44.11  ? 152  ARG B NH1   1 
ATOM   8242  N  NH2   . ARG D 2 152 ? 88.731  103.148 120.033 1.00 45.14  ? 152  ARG B NH2   1 
ATOM   8243  N  N     . PRO D 2 153 ? 82.428  108.785 117.426 1.00 58.11  ? 153  PRO B N     1 
ATOM   8244  C  CA    . PRO D 2 153 ? 81.587  107.617 117.697 1.00 55.93  ? 153  PRO B CA    1 
ATOM   8245  C  C     . PRO D 2 153 ? 81.249  106.932 116.397 1.00 53.30  ? 153  PRO B C     1 
ATOM   8246  O  O     . PRO D 2 153 ? 81.660  107.400 115.337 1.00 52.55  ? 153  PRO B O     1 
ATOM   8247  C  CB    . PRO D 2 153 ? 80.343  108.228 118.329 1.00 55.23  ? 153  PRO B CB    1 
ATOM   8248  C  CG    . PRO D 2 153 ? 80.858  109.485 118.927 1.00 62.13  ? 153  PRO B CG    1 
ATOM   8249  C  CD    . PRO D 2 153 ? 81.724  110.006 117.829 1.00 58.68  ? 153  PRO B CD    1 
ATOM   8250  N  N     . GLY D 2 154 ? 80.490  105.841 116.476 1.00 42.65  ? 154  GLY B N     1 
ATOM   8251  C  CA    . GLY D 2 154 ? 80.123  105.122 115.272 1.00 44.90  ? 154  GLY B CA    1 
ATOM   8252  C  C     . GLY D 2 154 ? 79.999  103.615 115.400 1.00 48.03  ? 154  GLY B C     1 
ATOM   8253  O  O     . GLY D 2 154 ? 80.262  103.039 116.446 1.00 50.34  ? 154  GLY B O     1 
ATOM   8254  N  N     . THR D 2 155 ? 79.587  102.976 114.310 1.00 55.28  ? 155  THR B N     1 
ATOM   8255  C  CA    . THR D 2 155 ? 79.410  101.533 114.275 1.00 49.08  ? 155  THR B CA    1 
ATOM   8256  C  C     . THR D 2 155 ? 80.052  100.894 113.046 1.00 47.49  ? 155  THR B C     1 
ATOM   8257  O  O     . THR D 2 155 ? 80.249  101.535 112.010 1.00 51.51  ? 155  THR B O     1 
ATOM   8258  C  CB    . THR D 2 155 ? 77.922  101.166 114.316 1.00 51.52  ? 155  THR B CB    1 
ATOM   8259  O  OG1   . THR D 2 155 ? 77.261  101.744 113.190 1.00 59.13  ? 155  THR B OG1   1 
ATOM   8260  C  CG2   . THR D 2 155 ? 77.283  101.702 115.586 1.00 58.67  ? 155  THR B CG2   1 
ATOM   8261  N  N     . THR D 2 156 ? 80.368  99.612  113.178 1.00 42.26  ? 156  THR B N     1 
ATOM   8262  C  CA    . THR D 2 156 ? 81.016  98.847  112.134 1.00 35.34  ? 156  THR B CA    1 
ATOM   8263  C  C     . THR D 2 156 ? 80.258  97.559  111.884 1.00 42.27  ? 156  THR B C     1 
ATOM   8264  O  O     . THR D 2 156 ? 80.052  96.773  112.799 1.00 46.54  ? 156  THR B O     1 
ATOM   8265  C  CB    . THR D 2 156 ? 82.442  98.508  112.569 1.00 43.50  ? 156  THR B CB    1 
ATOM   8266  O  OG1   . THR D 2 156 ? 83.153  99.735  112.795 1.00 30.25  ? 156  THR B OG1   1 
ATOM   8267  C  CG2   . THR D 2 156 ? 83.161  97.629  111.511 1.00 28.83  ? 156  THR B CG2   1 
ATOM   8268  N  N     . GLU D 2 157 ? 79.845  97.337  110.645 1.00 41.77  ? 157  GLU B N     1 
ATOM   8269  C  CA    . GLU D 2 157 ? 79.122  96.122  110.321 1.00 49.56  ? 157  GLU B CA    1 
ATOM   8270  C  C     . GLU D 2 157 ? 80.098  95.046  109.905 1.00 45.86  ? 157  GLU B C     1 
ATOM   8271  O  O     . GLU D 2 157 ? 81.017  95.300  109.141 1.00 55.74  ? 157  GLU B O     1 
ATOM   8272  C  CB    . GLU D 2 157 ? 78.171  96.326  109.150 1.00 51.50  ? 157  GLU B CB    1 
ATOM   8273  C  CG    . GLU D 2 157 ? 76.836  96.925  109.459 1.00 69.47  ? 157  GLU B CG    1 
ATOM   8274  C  CD    . GLU D 2 157 ? 75.901  96.820  108.261 1.00 75.44  ? 157  GLU B CD    1 
ATOM   8275  O  OE1   . GLU D 2 157 ? 74.768  97.333  108.343 1.00 77.10  ? 157  GLU B OE1   1 
ATOM   8276  O  OE2   . GLU D 2 157 ? 76.301  96.214  107.236 1.00 75.73  ? 157  GLU B OE2   1 
ATOM   8277  N  N     . VAL D 2 158 ? 79.888  93.839  110.399 1.00 43.70  ? 158  VAL B N     1 
ATOM   8278  C  CA    . VAL D 2 158 ? 80.716  92.713  110.019 1.00 41.48  ? 158  VAL B CA    1 
ATOM   8279  C  C     . VAL D 2 158 ? 79.802  91.611  109.496 1.00 39.48  ? 158  VAL B C     1 
ATOM   8280  O  O     . VAL D 2 158 ? 78.801  91.261  110.134 1.00 44.19  ? 158  VAL B O     1 
ATOM   8281  C  CB    . VAL D 2 158 ? 81.509  92.164  111.204 1.00 39.44  ? 158  VAL B CB    1 
ATOM   8282  C  CG1   . VAL D 2 158 ? 82.107  90.814  110.843 1.00 41.36  ? 158  VAL B CG1   1 
ATOM   8283  C  CG2   . VAL D 2 158 ? 82.583  93.133  111.579 1.00 36.91  ? 158  VAL B CG2   1 
ATOM   8284  N  N     . LYS D 2 159 ? 80.128  91.076  108.327 1.00 32.64  ? 159  LYS B N     1 
ATOM   8285  C  CA    . LYS D 2 159 ? 79.324  90.004  107.780 1.00 37.49  ? 159  LYS B CA    1 
ATOM   8286  C  C     . LYS D 2 159 ? 80.035  88.668  107.785 1.00 44.27  ? 159  LYS B C     1 
ATOM   8287  O  O     . LYS D 2 159 ? 81.105  88.491  107.182 1.00 43.16  ? 159  LYS B O     1 
ATOM   8288  C  CB    . LYS D 2 159 ? 78.888  90.282  106.352 1.00 42.37  ? 159  LYS B CB    1 
ATOM   8289  C  CG    . LYS D 2 159 ? 77.924  89.218  105.854 1.00 49.84  ? 159  LYS B CG    1 
ATOM   8290  C  CD    . LYS D 2 159 ? 77.667  89.371  104.381 1.00 64.10  ? 159  LYS B CD    1 
ATOM   8291  C  CE    . LYS D 2 159 ? 76.755  88.272  103.875 1.00 63.86  ? 159  LYS B CE    1 
ATOM   8292  N  NZ    . LYS D 2 159 ? 76.583  88.408  102.403 1.00 71.52  ? 159  LYS B NZ    1 
ATOM   8293  N  N     . ASP D 2 160 ? 79.424  87.725  108.483 1.00 41.02  ? 160  ASP B N     1 
ATOM   8294  C  CA    . ASP D 2 160 ? 79.941  86.398  108.552 1.00 33.87  ? 160  ASP B CA    1 
ATOM   8295  C  C     . ASP D 2 160 ? 79.022  85.591  107.642 1.00 36.77  ? 160  ASP B C     1 
ATOM   8296  O  O     . ASP D 2 160 ? 77.798  85.621  107.795 1.00 33.00  ? 160  ASP B O     1 
ATOM   8297  C  CB    . ASP D 2 160 ? 79.887  85.904  109.981 1.00 33.81  ? 160  ASP B CB    1 
ATOM   8298  C  CG    . ASP D 2 160 ? 80.385  84.473  110.109 1.00 41.34  ? 160  ASP B CG    1 
ATOM   8299  O  OD1   . ASP D 2 160 ? 79.535  83.547  110.035 1.00 36.17  ? 160  ASP B OD1   1 
ATOM   8300  O  OD2   . ASP D 2 160 ? 81.623  84.290  110.259 1.00 28.19  ? 160  ASP B OD2   1 
ATOM   8301  N  N     . GLU D 2 161 ? 79.601  84.880  106.682 1.00 32.48  ? 161  GLU B N     1 
ATOM   8302  C  CA    . GLU D 2 161 ? 78.788  84.117  105.748 1.00 30.24  ? 161  GLU B CA    1 
ATOM   8303  C  C     . GLU D 2 161 ? 77.921  83.035  106.406 1.00 34.88  ? 161  GLU B C     1 
ATOM   8304  O  O     . GLU D 2 161 ? 76.958  82.558  105.815 1.00 37.06  ? 161  GLU B O     1 
ATOM   8305  C  CB    . GLU D 2 161 ? 79.687  83.507  104.672 1.00 21.10  ? 161  GLU B CB    1 
ATOM   8306  C  CG    . GLU D 2 161 ? 80.454  84.531  103.837 1.00 42.61  ? 161  GLU B CG    1 
ATOM   8307  C  CD    . GLU D 2 161 ? 79.543  85.429  102.992 1.00 50.42  ? 161  GLU B CD    1 
ATOM   8308  O  OE1   . GLU D 2 161 ? 78.620  84.890  102.339 1.00 52.24  ? 161  GLU B OE1   1 
ATOM   8309  O  OE2   . GLU D 2 161 ? 79.756  86.665  102.969 1.00 44.28  ? 161  GLU B OE2   1 
ATOM   8310  N  N     . LEU D 2 162 ? 78.246  82.658  107.636 1.00 35.00  ? 162  LEU B N     1 
ATOM   8311  C  CA    . LEU D 2 162 ? 77.490  81.621  108.314 1.00 34.74  ? 162  LEU B CA    1 
ATOM   8312  C  C     . LEU D 2 162 ? 76.506  82.126  109.376 1.00 35.18  ? 162  LEU B C     1 
ATOM   8313  O  O     . LEU D 2 162 ? 75.567  81.416  109.733 1.00 38.02  ? 162  LEU B O     1 
ATOM   8314  C  CB    . LEU D 2 162 ? 78.449  80.631  108.954 1.00 23.72  ? 162  LEU B CB    1 
ATOM   8315  C  CG    . LEU D 2 162 ? 79.463  79.971  108.036 1.00 34.23  ? 162  LEU B CG    1 
ATOM   8316  C  CD1   . LEU D 2 162 ? 80.150  78.853  108.824 1.00 32.18  ? 162  LEU B CD1   1 
ATOM   8317  C  CD2   . LEU D 2 162 ? 78.800  79.406  106.809 1.00 28.30  ? 162  LEU B CD2   1 
ATOM   8318  N  N     . ARG D 2 163 ? 76.718  83.339  109.874 1.00 30.61  ? 163  ARG B N     1 
ATOM   8319  C  CA    . ARG D 2 163 ? 75.844  83.890  110.900 1.00 43.09  ? 163  ARG B CA    1 
ATOM   8320  C  C     . ARG D 2 163 ? 74.985  85.055  110.427 1.00 44.49  ? 163  ARG B C     1 
ATOM   8321  O  O     . ARG D 2 163 ? 73.871  85.249  110.893 1.00 44.92  ? 163  ARG B O     1 
ATOM   8322  C  CB    . ARG D 2 163 ? 76.676  84.329  112.105 1.00 31.12  ? 163  ARG B CB    1 
ATOM   8323  C  CG    . ARG D 2 163 ? 77.343  83.179  112.786 1.00 29.36  ? 163  ARG B CG    1 
ATOM   8324  C  CD    . ARG D 2 163 ? 78.488  83.626  113.638 1.00 32.37  ? 163  ARG B CD    1 
ATOM   8325  N  NE    . ARG D 2 163 ? 79.220  82.477  114.180 1.00 41.48  ? 163  ARG B NE    1 
ATOM   8326  C  CZ    . ARG D 2 163 ? 79.966  81.648  113.457 1.00 37.88  ? 163  ARG B CZ    1 
ATOM   8327  N  NH1   . ARG D 2 163 ? 80.096  81.829  112.147 1.00 32.57  ? 163  ARG B NH1   1 
ATOM   8328  N  NH2   . ARG D 2 163 ? 80.583  80.632  114.050 1.00 42.63  ? 163  ARG B NH2   1 
ATOM   8329  N  N     . GLY D 2 164 ? 75.502  85.833  109.495 1.00 50.15  ? 164  GLY B N     1 
ATOM   8330  C  CA    . GLY D 2 164 ? 74.749  86.973  109.020 1.00 52.44  ? 164  GLY B CA    1 
ATOM   8331  C  C     . GLY D 2 164 ? 75.486  88.227  109.441 1.00 57.36  ? 164  GLY B C     1 
ATOM   8332  O  O     . GLY D 2 164 ? 76.625  88.149  109.921 1.00 57.49  ? 164  GLY B O     1 
ATOM   8333  N  N     . VAL D 2 165 ? 74.850  89.383  109.273 1.00 54.60  ? 165  VAL B N     1 
ATOM   8334  C  CA    . VAL D 2 165 ? 75.484  90.640  109.644 1.00 53.72  ? 165  VAL B CA    1 
ATOM   8335  C  C     . VAL D 2 165 ? 75.445  90.863  111.162 1.00 51.55  ? 165  VAL B C     1 
ATOM   8336  O  O     . VAL D 2 165 ? 74.481  90.506  111.827 1.00 55.95  ? 165  VAL B O     1 
ATOM   8337  C  CB    . VAL D 2 165 ? 74.815  91.837  108.909 1.00 52.75  ? 165  VAL B CB    1 
ATOM   8338  C  CG1   . VAL D 2 165 ? 75.412  93.153  109.388 1.00 51.80  ? 165  VAL B CG1   1 
ATOM   8339  C  CG2   . VAL D 2 165 ? 75.039  91.713  107.418 1.00 41.98  ? 165  VAL B CG2   1 
ATOM   8340  N  N     . VAL D 2 166 ? 76.521  91.431  111.691 1.00 46.92  ? 166  VAL B N     1 
ATOM   8341  C  CA    . VAL D 2 166 ? 76.660  91.737  113.109 1.00 55.64  ? 166  VAL B CA    1 
ATOM   8342  C  C     . VAL D 2 166 ? 77.002  93.218  113.166 1.00 55.83  ? 166  VAL B C     1 
ATOM   8343  O  O     . VAL D 2 166 ? 77.756  93.690  112.330 1.00 61.79  ? 166  VAL B O     1 
ATOM   8344  C  CB    . VAL D 2 166 ? 77.845  90.985  113.720 1.00 57.59  ? 166  VAL B CB    1 
ATOM   8345  C  CG1   . VAL D 2 166 ? 77.988  91.364  115.172 1.00 64.24  ? 166  VAL B CG1   1 
ATOM   8346  C  CG2   . VAL D 2 166 ? 77.674  89.478  113.534 1.00 65.99  ? 166  VAL B CG2   1 
ATOM   8347  N  N     . VAL D 2 167 ? 76.478  93.964  114.128 1.00 48.84  ? 167  VAL B N     1 
ATOM   8348  C  CA    . VAL D 2 167 ? 76.822  95.371  114.164 1.00 45.73  ? 167  VAL B CA    1 
ATOM   8349  C  C     . VAL D 2 167 ? 77.484  95.776  115.464 1.00 49.82  ? 167  VAL B C     1 
ATOM   8350  O  O     . VAL D 2 167 ? 76.826  95.967  116.482 1.00 56.07  ? 167  VAL B O     1 
ATOM   8351  C  CB    . VAL D 2 167 ? 75.592  96.263  113.931 1.00 53.11  ? 167  VAL B CB    1 
ATOM   8352  C  CG1   . VAL D 2 167 ? 76.026  97.729  113.783 1.00 46.53  ? 167  VAL B CG1   1 
ATOM   8353  C  CG2   . VAL D 2 167 ? 74.845  95.799  112.687 1.00 58.66  ? 167  VAL B CG2   1 
ATOM   8354  N  N     . TYR D 2 168 ? 78.797  95.930  115.413 1.00 45.46  ? 168  TYR B N     1 
ATOM   8355  C  CA    . TYR D 2 168 ? 79.572  96.313  116.577 1.00 45.78  ? 168  TYR B CA    1 
ATOM   8356  C  C     . TYR D 2 168 ? 79.507  97.805  116.829 1.00 47.13  ? 168  TYR B C     1 
ATOM   8357  O  O     . TYR D 2 168 ? 79.441  98.602  115.908 1.00 50.45  ? 168  TYR B O     1 
ATOM   8358  C  CB    . TYR D 2 168 ? 81.045  95.906  116.390 1.00 41.25  ? 168  TYR B CB    1 
ATOM   8359  C  CG    . TYR D 2 168 ? 81.297  94.411  116.421 1.00 43.03  ? 168  TYR B CG    1 
ATOM   8360  C  CD1   . TYR D 2 168 ? 81.595  93.763  117.623 1.00 37.80  ? 168  TYR B CD1   1 
ATOM   8361  C  CD2   . TYR D 2 168 ? 81.216  93.635  115.255 1.00 34.61  ? 168  TYR B CD2   1 
ATOM   8362  C  CE1   . TYR D 2 168 ? 81.804  92.392  117.674 1.00 33.98  ? 168  TYR B CE1   1 
ATOM   8363  C  CE2   . TYR D 2 168 ? 81.425  92.259  115.295 1.00 41.03  ? 168  TYR B CE2   1 
ATOM   8364  C  CZ    . TYR D 2 168 ? 81.718  91.637  116.514 1.00 45.06  ? 168  TYR B CZ    1 
ATOM   8365  O  OH    . TYR D 2 168 ? 81.899  90.264  116.588 1.00 43.64  ? 168  TYR B OH    1 
ATOM   8366  N  N     . ASP D 2 169 ? 79.516  98.186  118.096 1.00 52.89  ? 169  ASP B N     1 
ATOM   8367  C  CA    . ASP D 2 169 ? 79.525  99.593  118.440 1.00 46.03  ? 169  ASP B CA    1 
ATOM   8368  C  C     . ASP D 2 169 ? 81.012  99.871  118.485 1.00 43.93  ? 169  ASP B C     1 
ATOM   8369  O  O     . ASP D 2 169 ? 81.770  99.055  119.022 1.00 42.76  ? 169  ASP B O     1 
ATOM   8370  C  CB    . ASP D 2 169 ? 78.897  99.819  119.813 1.00 47.08  ? 169  ASP B CB    1 
ATOM   8371  C  CG    . ASP D 2 169 ? 78.950  101.281 120.247 1.00 60.32  ? 169  ASP B CG    1 
ATOM   8372  O  OD1   . ASP D 2 169 ? 77.963  101.752 120.852 1.00 62.50  ? 169  ASP B OD1   1 
ATOM   8373  O  OD2   . ASP D 2 169 ? 79.977  101.960 119.995 1.00 57.30  ? 169  ASP B OD2   1 
ATOM   8374  N  N     . ASN D 2 170 ? 81.445  100.994 117.922 1.00 36.70  ? 170  ASN B N     1 
ATOM   8375  C  CA    . ASN D 2 170 ? 82.867  101.298 117.913 1.00 36.94  ? 170  ASN B CA    1 
ATOM   8376  C  C     . ASN D 2 170 ? 83.477  101.456 119.298 1.00 45.90  ? 170  ASN B C     1 
ATOM   8377  O  O     . ASN D 2 170 ? 84.706  101.427 119.455 1.00 42.53  ? 170  ASN B O     1 
ATOM   8378  C  CB    . ASN D 2 170 ? 83.113  102.536 117.101 1.00 36.55  ? 170  ASN B CB    1 
ATOM   8379  C  CG    . ASN D 2 170 ? 83.059  102.265 115.619 1.00 45.53  ? 170  ASN B CG    1 
ATOM   8380  O  OD1   . ASN D 2 170 ? 82.463  101.275 115.171 1.00 39.04  ? 170  ASN B OD1   1 
ATOM   8381  N  ND2   . ASN D 2 170 ? 83.672  103.152 114.840 1.00 35.86  ? 170  ASN B ND2   1 
ATOM   8382  N  N     . GLN D 2 171 ? 82.623  101.626 120.303 1.00 38.99  ? 171  GLN B N     1 
ATOM   8383  C  CA    . GLN D 2 171 ? 83.097  101.760 121.665 1.00 42.78  ? 171  GLN B CA    1 
ATOM   8384  C  C     . GLN D 2 171 ? 83.681  100.417 122.103 1.00 47.58  ? 171  GLN B C     1 
ATOM   8385  O  O     . GLN D 2 171 ? 84.425  100.349 123.071 1.00 52.24  ? 171  GLN B O     1 
ATOM   8386  C  CB    . GLN D 2 171 ? 81.948  102.149 122.603 1.00 52.57  ? 171  GLN B CB    1 
ATOM   8387  C  CG    . GLN D 2 171 ? 82.415  102.787 123.917 1.00 68.06  ? 171  GLN B CG    1 
ATOM   8388  C  CD    . GLN D 2 171 ? 83.166  104.107 123.704 1.00 75.53  ? 171  GLN B CD    1 
ATOM   8389  O  OE1   . GLN D 2 171 ? 84.364  104.219 124.004 1.00 76.83  ? 171  GLN B OE1   1 
ATOM   8390  N  NE2   . GLN D 2 171 ? 82.459  105.112 123.181 1.00 81.06  ? 171  GLN B NE2   1 
ATOM   8391  N  N     . GLU D 2 172 ? 83.351  99.348  121.384 1.00 47.19  ? 172  GLU B N     1 
ATOM   8392  C  CA    . GLU D 2 172 ? 83.866  98.026  121.729 1.00 50.57  ? 172  GLU B CA    1 
ATOM   8393  C  C     . GLU D 2 172 ? 85.100  97.630  120.927 1.00 51.45  ? 172  GLU B C     1 
ATOM   8394  O  O     . GLU D 2 172 ? 85.677  96.576  121.164 1.00 50.44  ? 172  GLU B O     1 
ATOM   8395  C  CB    . GLU D 2 172 ? 82.781  96.968  121.533 1.00 53.75  ? 172  GLU B CB    1 
ATOM   8396  C  CG    . GLU D 2 172 ? 81.524  97.221  122.346 1.00 62.16  ? 172  GLU B CG    1 
ATOM   8397  C  CD    . GLU D 2 172 ? 81.740  97.098  123.859 1.00 74.65  ? 172  GLU B CD    1 
ATOM   8398  O  OE1   . GLU D 2 172 ? 80.841  97.576  124.608 1.00 66.31  ? 172  GLU B OE1   1 
ATOM   8399  O  OE2   . GLU D 2 172 ? 82.785  96.524  124.284 1.00 64.60  ? 172  GLU B OE2   1 
ATOM   8400  N  N     . ILE D 2 173 ? 85.504  98.478  119.982 1.00 53.61  ? 173  ILE B N     1 
ATOM   8401  C  CA    . ILE D 2 173 ? 86.663  98.210  119.138 1.00 40.54  ? 173  ILE B CA    1 
ATOM   8402  C  C     . ILE D 2 173 ? 87.784  99.143  119.557 1.00 43.47  ? 173  ILE B C     1 
ATOM   8403  O  O     . ILE D 2 173 ? 87.747  100.335 119.290 1.00 51.72  ? 173  ILE B O     1 
ATOM   8404  C  CB    . ILE D 2 173 ? 86.323  98.477  117.664 1.00 45.49  ? 173  ILE B CB    1 
ATOM   8405  C  CG1   . ILE D 2 173 ? 85.040  97.749  117.291 1.00 38.22  ? 173  ILE B CG1   1 
ATOM   8406  C  CG2   . ILE D 2 173 ? 87.443  98.024  116.772 1.00 45.13  ? 173  ILE B CG2   1 
ATOM   8407  C  CD1   . ILE D 2 173 ? 84.550  98.122  115.932 1.00 38.71  ? 173  ILE B CD1   1 
ATOM   8408  N  N     . PRO D 2 174 ? 88.809  98.612  120.217 1.00 38.69  ? 174  PRO B N     1 
ATOM   8409  C  CA    . PRO D 2 174 ? 89.931  99.432  120.666 1.00 34.51  ? 174  PRO B CA    1 
ATOM   8410  C  C     . PRO D 2 174 ? 90.845  99.944  119.581 1.00 41.80  ? 174  PRO B C     1 
ATOM   8411  O  O     . PRO D 2 174 ? 90.893  99.386  118.488 1.00 42.75  ? 174  PRO B O     1 
ATOM   8412  C  CB    . PRO D 2 174 ? 90.668  98.504  121.605 1.00 34.07  ? 174  PRO B CB    1 
ATOM   8413  C  CG    . PRO D 2 174 ? 90.416  97.175  121.020 1.00 35.49  ? 174  PRO B CG    1 
ATOM   8414  C  CD    . PRO D 2 174 ? 88.986  97.211  120.615 1.00 37.76  ? 174  PRO B CD    1 
ATOM   8415  N  N     . ASP D 2 175 ? 91.566  101.022 119.880 1.00 44.46  ? 175  ASP B N     1 
ATOM   8416  C  CA    . ASP D 2 175 ? 92.527  101.556 118.922 1.00 48.45  ? 175  ASP B CA    1 
ATOM   8417  C  C     . ASP D 2 175 ? 93.710  100.617 119.099 1.00 46.74  ? 175  ASP B C     1 
ATOM   8418  O  O     . ASP D 2 175 ? 94.645  100.931 119.841 1.00 49.83  ? 175  ASP B O     1 
ATOM   8419  C  CB    . ASP D 2 175 ? 92.974  102.975 119.284 1.00 54.49  ? 175  ASP B CB    1 
ATOM   8420  C  CG    . ASP D 2 175 ? 91.951  104.035 118.927 1.00 49.92  ? 175  ASP B CG    1 
ATOM   8421  O  OD1   . ASP D 2 175 ? 90.950  103.723 118.248 1.00 51.68  ? 175  ASP B OD1   1 
ATOM   8422  O  OD2   . ASP D 2 175 ? 92.173  105.198 119.330 1.00 57.16  ? 175  ASP B OD2   1 
ATOM   8423  N  N     . VAL D 2 176 ? 93.665  99.463  118.436 1.00 43.25  ? 176  VAL B N     1 
ATOM   8424  C  CA    . VAL D 2 176 ? 94.732  98.478  118.577 1.00 35.88  ? 176  VAL B CA    1 
ATOM   8425  C  C     . VAL D 2 176 ? 96.076  98.882  117.999 1.00 39.87  ? 176  VAL B C     1 
ATOM   8426  O  O     . VAL D 2 176 ? 96.174  99.640  117.025 1.00 41.47  ? 176  VAL B O     1 
ATOM   8427  C  CB    . VAL D 2 176 ? 94.369  97.119  117.932 1.00 37.39  ? 176  VAL B CB    1 
ATOM   8428  C  CG1   . VAL D 2 176 ? 93.059  96.580  118.520 1.00 31.18  ? 176  VAL B CG1   1 
ATOM   8429  C  CG2   . VAL D 2 176 ? 94.286  97.283  116.421 1.00 32.36  ? 176  VAL B CG2   1 
ATOM   8430  N  N     . VAL D 2 177 ? 97.118  98.376  118.639 1.00 34.68  ? 177  VAL B N     1 
ATOM   8431  C  CA    . VAL D 2 177 ? 98.462  98.592  118.171 1.00 38.24  ? 177  VAL B CA    1 
ATOM   8432  C  C     . VAL D 2 177 ? 98.599  97.829  116.836 1.00 35.78  ? 177  VAL B C     1 
ATOM   8433  O  O     . VAL D 2 177 ? 98.289  96.648  116.754 1.00 37.22  ? 177  VAL B O     1 
ATOM   8434  C  CB    . VAL D 2 177 ? 99.430  98.035  119.188 1.00 37.35  ? 177  VAL B CB    1 
ATOM   8435  C  CG1   . VAL D 2 177 ? 100.830 97.889  118.582 1.00 40.20  ? 177  VAL B CG1   1 
ATOM   8436  C  CG2   . VAL D 2 177 ? 99.409  98.929  120.399 1.00 40.95  ? 177  VAL B CG2   1 
ATOM   8437  N  N     . LEU D 2 178 ? 99.041  98.518  115.799 1.00 37.13  ? 178  LEU B N     1 
ATOM   8438  C  CA    . LEU D 2 178 ? 99.231  97.915  114.496 1.00 39.84  ? 178  LEU B CA    1 
ATOM   8439  C  C     . LEU D 2 178 ? 100.727 97.618  114.324 1.00 49.38  ? 178  LEU B C     1 
ATOM   8440  O  O     . LEU D 2 178 ? 101.110 96.498  113.964 1.00 54.40  ? 178  LEU B O     1 
ATOM   8441  C  CB    . LEU D 2 178 ? 98.741  98.876  113.424 1.00 31.43  ? 178  LEU B CB    1 
ATOM   8442  C  CG    . LEU D 2 178 ? 97.300  99.326  113.639 1.00 32.70  ? 178  LEU B CG    1 
ATOM   8443  C  CD1   . LEU D 2 178 ? 96.928  100.385 112.611 1.00 38.06  ? 178  LEU B CD1   1 
ATOM   8444  C  CD2   . LEU D 2 178 ? 96.377  98.144  113.491 1.00 38.04  ? 178  LEU B CD2   1 
ATOM   8445  N  N     . LEU D 2 179 ? 101.566 98.620  114.596 1.00 49.48  ? 179  LEU B N     1 
ATOM   8446  C  CA    . LEU D 2 179 ? 103.021 98.466  114.501 1.00 53.38  ? 179  LEU B CA    1 
ATOM   8447  C  C     . LEU D 2 179 ? 103.602 98.623  115.899 1.00 46.96  ? 179  LEU B C     1 
ATOM   8448  O  O     . LEU D 2 179 ? 103.409 99.655  116.526 1.00 45.16  ? 179  LEU B O     1 
ATOM   8449  C  CB    . LEU D 2 179 ? 103.639 99.537  113.581 1.00 54.59  ? 179  LEU B CB    1 
ATOM   8450  C  CG    . LEU D 2 179 ? 104.879 99.110  112.768 1.00 60.90  ? 179  LEU B CG    1 
ATOM   8451  C  CD1   . LEU D 2 179 ? 105.643 100.334 112.294 1.00 56.61  ? 179  LEU B CD1   1 
ATOM   8452  C  CD2   . LEU D 2 179 ? 105.795 98.231  113.609 1.00 66.69  ? 179  LEU B CD2   1 
ATOM   8453  N  N     . LYS D 2 180 ? 104.296 97.593  116.378 1.00 51.97  ? 180  LYS B N     1 
ATOM   8454  C  CA    . LYS D 2 180 ? 104.910 97.605  117.702 1.00 57.20  ? 180  LYS B CA    1 
ATOM   8455  C  C     . LYS D 2 180 ? 106.177 98.459  117.695 1.00 62.96  ? 180  LYS B C     1 
ATOM   8456  O  O     . LYS D 2 180 ? 106.786 98.665  116.643 1.00 59.99  ? 180  LYS B O     1 
ATOM   8457  C  CB    . LYS D 2 180 ? 105.234 96.174  118.144 1.00 54.41  ? 180  LYS B CB    1 
ATOM   8458  C  CG    . LYS D 2 180 ? 104.036 95.410  118.668 1.00 53.49  ? 180  LYS B CG    1 
ATOM   8459  C  CD    . LYS D 2 180 ? 103.904 94.049  118.025 1.00 52.94  ? 180  LYS B CD    1 
ATOM   8460  C  CE    . LYS D 2 180 ? 105.075 93.143  118.369 1.00 54.40  ? 180  LYS B CE    1 
ATOM   8461  N  NZ    . LYS D 2 180 ? 104.771 91.738  117.941 1.00 55.60  ? 180  LYS B NZ    1 
ATOM   8462  N  N     . SER D 2 181 ? 106.583 98.948  118.866 1.00 64.35  ? 181  SER B N     1 
ATOM   8463  C  CA    . SER D 2 181 ? 107.761 99.804  118.932 1.00 66.81  ? 181  SER B CA    1 
ATOM   8464  C  C     . SER D 2 181 ? 109.060 99.156  118.429 1.00 67.79  ? 181  SER B C     1 
ATOM   8465  O  O     . SER D 2 181 ? 110.036 99.862  118.162 1.00 67.53  ? 181  SER B O     1 
ATOM   8466  C  CB    . SER D 2 181 ? 107.942 100.364 120.354 1.00 61.88  ? 181  SER B CB    1 
ATOM   8467  O  OG    . SER D 2 181 ? 108.093 99.334  121.315 1.00 61.79  ? 181  SER B OG    1 
ATOM   8468  N  N     . ASP D 2 182 ? 109.087 97.835  118.278 1.00 64.52  ? 182  ASP B N     1 
ATOM   8469  C  CA    . ASP D 2 182 ? 110.309 97.215  117.788 1.00 68.16  ? 182  ASP B CA    1 
ATOM   8470  C  C     . ASP D 2 182 ? 110.291 97.093  116.271 1.00 66.59  ? 182  ASP B C     1 
ATOM   8471  O  O     . ASP D 2 182 ? 111.123 96.392  115.685 1.00 68.61  ? 182  ASP B O     1 
ATOM   8472  C  CB    . ASP D 2 182 ? 110.522 95.843  118.420 1.00 70.34  ? 182  ASP B CB    1 
ATOM   8473  C  CG    . ASP D 2 182 ? 109.516 94.832  117.958 1.00 77.15  ? 182  ASP B CG    1 
ATOM   8474  O  OD1   . ASP D 2 182 ? 109.663 93.639  118.309 1.00 79.33  ? 182  ASP B OD1   1 
ATOM   8475  O  OD2   . ASP D 2 182 ? 108.576 95.236  117.244 1.00 80.52  ? 182  ASP B OD2   1 
ATOM   8476  N  N     . GLY D 2 183 ? 109.345 97.785  115.640 1.00 61.49  ? 183  GLY B N     1 
ATOM   8477  C  CA    . GLY D 2 183 ? 109.232 97.736  114.190 1.00 62.30  ? 183  GLY B CA    1 
ATOM   8478  C  C     . GLY D 2 183 ? 108.461 96.537  113.652 1.00 62.33  ? 183  GLY B C     1 
ATOM   8479  O  O     . GLY D 2 183 ? 108.256 96.415  112.445 1.00 64.61  ? 183  GLY B O     1 
ATOM   8480  N  N     . TYR D 2 184 ? 108.045 95.647  114.550 1.00 60.91  ? 184  TYR B N     1 
ATOM   8481  C  CA    . TYR D 2 184 ? 107.282 94.460  114.195 1.00 56.46  ? 184  TYR B CA    1 
ATOM   8482  C  C     . TYR D 2 184 ? 105.793 94.776  114.183 1.00 56.09  ? 184  TYR B C     1 
ATOM   8483  O  O     . TYR D 2 184 ? 105.315 95.577  114.974 1.00 59.31  ? 184  TYR B O     1 
ATOM   8484  C  CB    . TYR D 2 184 ? 107.562 93.368  115.205 1.00 57.31  ? 184  TYR B CB    1 
ATOM   8485  C  CG    . TYR D 2 184 ? 108.813 92.585  114.923 1.00 64.67  ? 184  TYR B CG    1 
ATOM   8486  C  CD1   . TYR D 2 184 ? 108.771 91.459  114.112 1.00 66.41  ? 184  TYR B CD1   1 
ATOM   8487  C  CD2   . TYR D 2 184 ? 110.031 92.942  115.494 1.00 66.76  ? 184  TYR B CD2   1 
ATOM   8488  C  CE1   . TYR D 2 184 ? 109.906 90.692  113.883 1.00 73.47  ? 184  TYR B CE1   1 
ATOM   8489  C  CE2   . TYR D 2 184 ? 111.179 92.181  115.267 1.00 72.07  ? 184  TYR B CE2   1 
ATOM   8490  C  CZ    . TYR D 2 184 ? 111.106 91.053  114.464 1.00 70.73  ? 184  TYR B CZ    1 
ATOM   8491  O  OH    . TYR D 2 184 ? 112.211 90.255  114.266 1.00 68.37  ? 184  TYR B OH    1 
ATOM   8492  N  N     . PRO D 2 185 ? 105.033 94.142  113.283 1.00 55.89  ? 185  PRO B N     1 
ATOM   8493  C  CA    . PRO D 2 185 ? 103.595 94.406  113.217 1.00 48.23  ? 185  PRO B CA    1 
ATOM   8494  C  C     . PRO D 2 185 ? 102.829 93.492  114.155 1.00 46.96  ? 185  PRO B C     1 
ATOM   8495  O  O     . PRO D 2 185 ? 103.350 92.454  114.584 1.00 42.63  ? 185  PRO B O     1 
ATOM   8496  C  CB    . PRO D 2 185 ? 103.277 94.064  111.783 1.00 43.90  ? 185  PRO B CB    1 
ATOM   8497  C  CG    . PRO D 2 185 ? 104.069 92.783  111.627 1.00 43.29  ? 185  PRO B CG    1 
ATOM   8498  C  CD    . PRO D 2 185 ? 105.426 93.199  112.218 1.00 50.24  ? 185  PRO B CD    1 
ATOM   8499  N  N     . THR D 2 186 ? 101.599 93.875  114.480 1.00 39.83  ? 186  THR B N     1 
ATOM   8500  C  CA    . THR D 2 186 ? 100.777 93.007  115.307 1.00 39.01  ? 186  THR B CA    1 
ATOM   8501  C  C     . THR D 2 186 ? 99.968  92.182  114.306 1.00 41.96  ? 186  THR B C     1 
ATOM   8502  O  O     . THR D 2 186 ? 99.970  92.450  113.084 1.00 34.93  ? 186  THR B O     1 
ATOM   8503  C  CB    . THR D 2 186 ? 99.791  93.780  116.268 1.00 41.17  ? 186  THR B CB    1 
ATOM   8504  O  OG1   . THR D 2 186 ? 98.799  94.477  115.512 1.00 27.80  ? 186  THR B OG1   1 
ATOM   8505  C  CG2   . THR D 2 186 ? 100.560 94.773  117.157 1.00 49.70  ? 186  THR B CG2   1 
ATOM   8506  N  N     . TYR D 2 187 ? 99.294  91.170  114.833 1.00 37.10  ? 187  TYR B N     1 
ATOM   8507  C  CA    . TYR D 2 187 ? 98.483  90.279  114.033 1.00 29.85  ? 187  TYR B CA    1 
ATOM   8508  C  C     . TYR D 2 187 ? 97.429  91.002  113.181 1.00 31.65  ? 187  TYR B C     1 
ATOM   8509  O  O     . TYR D 2 187 ? 97.149  90.608  112.048 1.00 29.78  ? 187  TYR B O     1 
ATOM   8510  C  CB    . TYR D 2 187 ? 97.810  89.274  114.964 1.00 32.71  ? 187  TYR B CB    1 
ATOM   8511  C  CG    . TYR D 2 187 ? 96.654  88.619  114.321 1.00 32.62  ? 187  TYR B CG    1 
ATOM   8512  C  CD1   . TYR D 2 187 ? 96.843  87.658  113.333 1.00 28.10  ? 187  TYR B CD1   1 
ATOM   8513  C  CD2   . TYR D 2 187 ? 95.368  89.071  114.576 1.00 28.30  ? 187  TYR B CD2   1 
ATOM   8514  C  CE1   . TYR D 2 187 ? 95.774  87.176  112.604 1.00 39.84  ? 187  TYR B CE1   1 
ATOM   8515  C  CE2   . TYR D 2 187 ? 94.289  88.601  113.852 1.00 36.05  ? 187  TYR B CE2   1 
ATOM   8516  C  CZ    . TYR D 2 187 ? 94.495  87.659  112.871 1.00 38.90  ? 187  TYR B CZ    1 
ATOM   8517  O  OH    . TYR D 2 187 ? 93.420  87.199  112.163 1.00 52.06  ? 187  TYR B OH    1 
ATOM   8518  N  N     . HIS D 2 188 ? 96.844  92.064  113.715 1.00 31.33  ? 188  HIS B N     1 
ATOM   8519  C  CA    . HIS D 2 188 ? 95.809  92.780  112.982 1.00 30.60  ? 188  HIS B CA    1 
ATOM   8520  C  C     . HIS D 2 188 ? 96.309  93.510  111.754 1.00 34.27  ? 188  HIS B C     1 
ATOM   8521  O  O     . HIS D 2 188 ? 95.603  93.655  110.765 1.00 36.97  ? 188  HIS B O     1 
ATOM   8522  C  CB    . HIS D 2 188 ? 95.117  93.759  113.900 1.00 32.78  ? 188  HIS B CB    1 
ATOM   8523  C  CG    . HIS D 2 188 ? 94.510  93.121  115.105 1.00 32.78  ? 188  HIS B CG    1 
ATOM   8524  N  ND1   . HIS D 2 188 ? 93.393  92.315  115.039 1.00 32.14  ? 188  HIS B ND1   1 
ATOM   8525  C  CD2   . HIS D 2 188 ? 94.866  93.169  116.408 1.00 30.82  ? 188  HIS B CD2   1 
ATOM   8526  C  CE1   . HIS D 2 188 ? 93.088  91.895  116.253 1.00 29.73  ? 188  HIS B CE1   1 
ATOM   8527  N  NE2   . HIS D 2 188 ? 93.965  92.398  117.103 1.00 37.27  ? 188  HIS B NE2   1 
ATOM   8528  N  N     . LEU D 2 189 ? 97.539  93.972  111.796 1.00 36.48  ? 189  LEU B N     1 
ATOM   8529  C  CA    . LEU D 2 189 ? 98.050  94.677  110.637 1.00 37.50  ? 189  LEU B CA    1 
ATOM   8530  C  C     . LEU D 2 189 ? 98.445  93.652  109.582 1.00 39.12  ? 189  LEU B C     1 
ATOM   8531  O  O     . LEU D 2 189 ? 97.942  93.671  108.460 1.00 34.53  ? 189  LEU B O     1 
ATOM   8532  C  CB    . LEU D 2 189 ? 99.274  95.495  111.028 1.00 29.52  ? 189  LEU B CB    1 
ATOM   8533  C  CG    . LEU D 2 189 ? 99.609  96.764  110.264 1.00 38.70  ? 189  LEU B CG    1 
ATOM   8534  C  CD1   . LEU D 2 189 ? 101.123 96.939  110.323 1.00 41.06  ? 189  LEU B CD1   1 
ATOM   8535  C  CD2   . LEU D 2 189 ? 99.130  96.691  108.836 1.00 36.32  ? 189  LEU B CD2   1 
ATOM   8536  N  N     . ALA D 2 190 ? 99.343  92.746  109.979 1.00 39.46  ? 190  ALA B N     1 
ATOM   8537  C  CA    . ALA D 2 190 ? 99.874  91.717  109.093 1.00 37.55  ? 190  ALA B CA    1 
ATOM   8538  C  C     . ALA D 2 190 ? 98.809  90.924  108.359 1.00 31.46  ? 190  ALA B C     1 
ATOM   8539  O  O     . ALA D 2 190 ? 98.888  90.731  107.154 1.00 30.24  ? 190  ALA B O     1 
ATOM   8540  C  CB    . ALA D 2 190 ? 100.787 90.790  109.875 1.00 30.95  ? 190  ALA B CB    1 
ATOM   8541  N  N     . ASN D 2 191 ? 97.806  90.487  109.103 1.00 32.31  ? 191  ASN B N     1 
ATOM   8542  C  CA    . ASN D 2 191 ? 96.695  89.710  108.570 1.00 29.78  ? 191  ASN B CA    1 
ATOM   8543  C  C     . ASN D 2 191 ? 96.022  90.359  107.352 1.00 34.03  ? 191  ASN B C     1 
ATOM   8544  O  O     . ASN D 2 191 ? 95.878  89.742  106.293 1.00 26.96  ? 191  ASN B O     1 
ATOM   8545  C  CB    . ASN D 2 191 ? 95.664  89.524  109.679 1.00 40.82  ? 191  ASN B CB    1 
ATOM   8546  C  CG    . ASN D 2 191 ? 94.617  88.507  109.335 1.00 47.60  ? 191  ASN B CG    1 
ATOM   8547  O  OD1   . ASN D 2 191 ? 93.477  88.848  108.989 1.00 52.56  ? 191  ASN B OD1   1 
ATOM   8548  N  ND2   . ASN D 2 191 ? 94.995  87.237  109.426 1.00 47.25  ? 191  ASN B ND2   1 
ATOM   8549  N  N     . VAL D 2 192 ? 95.606  91.608  107.515 1.00 28.28  ? 192  VAL B N     1 
ATOM   8550  C  CA    . VAL D 2 192 ? 94.926  92.316  106.453 1.00 34.57  ? 192  VAL B CA    1 
ATOM   8551  C  C     . VAL D 2 192 ? 95.834  92.642  105.262 1.00 36.99  ? 192  VAL B C     1 
ATOM   8552  O  O     . VAL D 2 192 ? 95.408  92.549  104.112 1.00 43.51  ? 192  VAL B O     1 
ATOM   8553  C  CB    . VAL D 2 192 ? 94.282  93.613  107.005 1.00 37.60  ? 192  VAL B CB    1 
ATOM   8554  C  CG1   . VAL D 2 192 ? 93.723  94.475  105.861 1.00 30.32  ? 192  VAL B CG1   1 
ATOM   8555  C  CG2   . VAL D 2 192 ? 93.169  93.238  107.986 1.00 34.89  ? 192  VAL B CG2   1 
ATOM   8556  N  N     . VAL D 2 193 ? 97.085  93.001  105.531 1.00 35.60  ? 193  VAL B N     1 
ATOM   8557  C  CA    . VAL D 2 193 ? 98.021  93.329  104.458 1.00 36.77  ? 193  VAL B CA    1 
ATOM   8558  C  C     . VAL D 2 193 ? 98.311  92.101  103.568 1.00 35.83  ? 193  VAL B C     1 
ATOM   8559  O  O     . VAL D 2 193 ? 98.196  92.158  102.338 1.00 31.26  ? 193  VAL B O     1 
ATOM   8560  C  CB    . VAL D 2 193 ? 99.362  93.899  105.040 1.00 37.21  ? 193  VAL B CB    1 
ATOM   8561  C  CG1   . VAL D 2 193 ? 100.447 93.890  103.980 1.00 33.86  ? 193  VAL B CG1   1 
ATOM   8562  C  CG2   . VAL D 2 193 ? 99.156  95.333  105.553 1.00 26.49  ? 193  VAL B CG2   1 
ATOM   8563  N  N     . ASP D 2 194 ? 98.658  90.991  104.204 1.00 27.85  ? 194  ASP B N     1 
ATOM   8564  C  CA    . ASP D 2 194 ? 98.981  89.775  103.491 1.00 29.13  ? 194  ASP B CA    1 
ATOM   8565  C  C     . ASP D 2 194 ? 97.768  89.114  102.803 1.00 30.66  ? 194  ASP B C     1 
ATOM   8566  O  O     . ASP D 2 194 ? 97.876  88.651  101.670 1.00 27.10  ? 194  ASP B O     1 
ATOM   8567  C  CB    . ASP D 2 194 ? 99.685  88.812  104.452 1.00 30.19  ? 194  ASP B CB    1 
ATOM   8568  C  CG    . ASP D 2 194 ? 101.040 89.359  104.949 1.00 39.14  ? 194  ASP B CG    1 
ATOM   8569  O  OD1   . ASP D 2 194 ? 101.631 88.786  105.889 1.00 37.63  ? 194  ASP B OD1   1 
ATOM   8570  O  OD2   . ASP D 2 194 ? 101.526 90.363  104.398 1.00 40.02  ? 194  ASP B OD2   1 
ATOM   8571  N  N     . ASP D 2 195 ? 96.619  89.066  103.466 1.00 25.14  ? 195  ASP B N     1 
ATOM   8572  C  CA    . ASP D 2 195 ? 95.452  88.481  102.816 1.00 35.62  ? 195  ASP B CA    1 
ATOM   8573  C  C     . ASP D 2 195 ? 95.176  89.266  101.526 1.00 36.09  ? 195  ASP B C     1 
ATOM   8574  O  O     . ASP D 2 195 ? 94.833  88.692  100.495 1.00 40.47  ? 195  ASP B O     1 
ATOM   8575  C  CB    . ASP D 2 195 ? 94.225  88.533  103.738 1.00 35.04  ? 195  ASP B CB    1 
ATOM   8576  C  CG    . ASP D 2 195 ? 94.220  87.416  104.773 1.00 36.87  ? 195  ASP B CG    1 
ATOM   8577  O  OD1   . ASP D 2 195 ? 93.473  87.535  105.767 1.00 30.55  ? 195  ASP B OD1   1 
ATOM   8578  O  OD2   . ASP D 2 195 ? 94.954  86.418  104.586 1.00 33.67  ? 195  ASP B OD2   1 
ATOM   8579  N  N     . HIS D 2 196 ? 95.333  90.583  101.585 1.00 40.79  ? 196  HIS B N     1 
ATOM   8580  C  CA    . HIS D 2 196 ? 95.122  91.414  100.401 1.00 42.75  ? 196  HIS B CA    1 
ATOM   8581  C  C     . HIS D 2 196 ? 96.201  91.172  99.327  1.00 40.29  ? 196  HIS B C     1 
ATOM   8582  O  O     . HIS D 2 196 ? 95.889  90.832  98.185  1.00 36.21  ? 196  HIS B O     1 
ATOM   8583  C  CB    . HIS D 2 196 ? 95.132  92.890  100.780 1.00 39.92  ? 196  HIS B CB    1 
ATOM   8584  C  CG    . HIS D 2 196 ? 95.048  93.802  99.600  1.00 41.99  ? 196  HIS B CG    1 
ATOM   8585  N  ND1   . HIS D 2 196 ? 93.887  93.977  98.880  1.00 39.86  ? 196  HIS B ND1   1 
ATOM   8586  C  CD2   . HIS D 2 196 ? 95.987  94.575  99.001  1.00 35.56  ? 196  HIS B CD2   1 
ATOM   8587  C  CE1   . HIS D 2 196 ? 94.112  94.822  97.888  1.00 37.47  ? 196  HIS B CE1   1 
ATOM   8588  N  NE2   . HIS D 2 196 ? 95.378  95.199  97.941  1.00 43.79  ? 196  HIS B NE2   1 
ATOM   8589  N  N     . LEU D 2 197 ? 97.467  91.345  99.696  1.00 37.53  ? 197  LEU B N     1 
ATOM   8590  C  CA    . LEU D 2 197 ? 98.567  91.146  98.747  1.00 42.64  ? 197  LEU B CA    1 
ATOM   8591  C  C     . LEU D 2 197 ? 98.691  89.727  98.158  1.00 46.31  ? 197  LEU B C     1 
ATOM   8592  O  O     . LEU D 2 197 ? 99.217  89.578  97.050  1.00 46.77  ? 197  LEU B O     1 
ATOM   8593  C  CB    . LEU D 2 197 ? 99.898  91.538  99.385  1.00 34.99  ? 197  LEU B CB    1 
ATOM   8594  C  CG    . LEU D 2 197 ? 100.132 93.003  99.778  1.00 41.12  ? 197  LEU B CG    1 
ATOM   8595  C  CD1   . LEU D 2 197 ? 101.536 93.143  100.426 1.00 32.82  ? 197  LEU B CD1   1 
ATOM   8596  C  CD2   . LEU D 2 197 ? 100.020 93.895  98.535  1.00 37.41  ? 197  LEU B CD2   1 
ATOM   8597  N  N     . MET D 2 198 ? 98.236  88.700  98.894  1.00 38.94  ? 198  MET B N     1 
ATOM   8598  C  CA    . MET D 2 198 ? 98.282  87.319  98.412  1.00 31.61  ? 198  MET B CA    1 
ATOM   8599  C  C     . MET D 2 198 ? 96.976  86.922  97.715  1.00 33.21  ? 198  MET B C     1 
ATOM   8600  O  O     . MET D 2 198 ? 96.793  85.765  97.328  1.00 29.80  ? 198  MET B O     1 
ATOM   8601  C  CB    . MET D 2 198 ? 98.559  86.348  99.558  1.00 33.35  ? 198  MET B CB    1 
ATOM   8602  C  CG    . MET D 2 198 ? 99.919  86.526  100.233 1.00 30.45  ? 198  MET B CG    1 
ATOM   8603  S  SD    . MET D 2 198 ? 100.162 85.393  101.611 1.00 31.24  ? 198  MET B SD    1 
ATOM   8604  C  CE    . MET D 2 198 ? 101.788 85.972  102.223 1.00 26.19  ? 198  MET B CE    1 
ATOM   8605  N  N     . GLY D 2 199 ? 96.062  87.881  97.591  1.00 31.48  ? 199  GLY B N     1 
ATOM   8606  C  CA    . GLY D 2 199 ? 94.796  87.646  96.910  1.00 26.11  ? 199  GLY B CA    1 
ATOM   8607  C  C     . GLY D 2 199 ? 93.722  86.813  97.584  1.00 30.29  ? 199  GLY B C     1 
ATOM   8608  O  O     . GLY D 2 199 ? 92.835  86.304  96.903  1.00 30.52  ? 199  GLY B O     1 
ATOM   8609  N  N     . VAL D 2 200 ? 93.790  86.680  98.905  1.00 22.31  ? 200  VAL B N     1 
ATOM   8610  C  CA    . VAL D 2 200 ? 92.830  85.896  99.669  1.00 20.36  ? 200  VAL B CA    1 
ATOM   8611  C  C     . VAL D 2 200 ? 91.402  86.455  99.519  1.00 25.92  ? 200  VAL B C     1 
ATOM   8612  O  O     . VAL D 2 200 ? 91.131  87.622  99.807  1.00 21.05  ? 200  VAL B O     1 
ATOM   8613  C  CB    . VAL D 2 200 ? 93.265  85.873  101.166 1.00 21.40  ? 200  VAL B CB    1 
ATOM   8614  C  CG1   . VAL D 2 200 ? 92.271  85.080  102.016 1.00 28.22  ? 200  VAL B CG1   1 
ATOM   8615  C  CG2   . VAL D 2 200 ? 94.634  85.217  101.283 1.00 24.70  ? 200  VAL B CG2   1 
ATOM   8616  N  N     . THR D 2 201 ? 90.480  85.610  99.093  1.00 21.22  ? 201  THR B N     1 
ATOM   8617  C  CA    . THR D 2 201 ? 89.092  86.054  98.879  1.00 22.59  ? 201  THR B CA    1 
ATOM   8618  C  C     . THR D 2 201 ? 88.137  85.441  99.895  1.00 27.94  ? 201  THR B C     1 
ATOM   8619  O  O     . THR D 2 201 ? 86.999  85.887  100.023 1.00 30.57  ? 201  THR B O     1 
ATOM   8620  C  CB    . THR D 2 201 ? 88.556  85.596  97.516  1.00 27.50  ? 201  THR B CB    1 
ATOM   8621  O  OG1   . THR D 2 201 ? 88.582  84.156  97.472  1.00 27.31  ? 201  THR B OG1   1 
ATOM   8622  C  CG2   . THR D 2 201 ? 89.401  86.140  96.376  1.00 22.61  ? 201  THR B CG2   1 
ATOM   8623  N  N     . ASP D 2 202 ? 88.591  84.397  100.588 1.00 26.89  ? 202  ASP B N     1 
ATOM   8624  C  CA    . ASP D 2 202 ? 87.756  83.711  101.568 1.00 24.46  ? 202  ASP B CA    1 
ATOM   8625  C  C     . ASP D 2 202 ? 88.535  83.365  102.821 1.00 28.72  ? 202  ASP B C     1 
ATOM   8626  O  O     . ASP D 2 202 ? 89.377  82.455  102.796 1.00 25.71  ? 202  ASP B O     1 
ATOM   8627  C  CB    . ASP D 2 202 ? 87.181  82.438  100.943 1.00 28.00  ? 202  ASP B CB    1 
ATOM   8628  C  CG    . ASP D 2 202 ? 86.231  82.736  99.770  1.00 40.63  ? 202  ASP B CG    1 
ATOM   8629  O  OD1   . ASP D 2 202 ? 84.990  82.689  99.955  1.00 42.22  ? 202  ASP B OD1   1 
ATOM   8630  O  OD2   . ASP D 2 202 ? 86.722  83.033  98.662  1.00 37.38  ? 202  ASP B OD2   1 
ATOM   8631  N  N     . VAL D 2 203 ? 88.277  84.109  103.899 1.00 21.85  ? 203  VAL B N     1 
ATOM   8632  C  CA    . VAL D 2 203 ? 88.938  83.876  105.175 1.00 21.05  ? 203  VAL B CA    1 
ATOM   8633  C  C     . VAL D 2 203 ? 88.113  82.904  106.008 1.00 22.39  ? 203  VAL B C     1 
ATOM   8634  O  O     . VAL D 2 203 ? 87.029  83.246  106.477 1.00 27.84  ? 203  VAL B O     1 
ATOM   8635  C  CB    . VAL D 2 203 ? 89.108  85.195  105.965 1.00 29.18  ? 203  VAL B CB    1 
ATOM   8636  C  CG1   . VAL D 2 203 ? 89.709  84.937  107.375 1.00 28.66  ? 203  VAL B CG1   1 
ATOM   8637  C  CG2   . VAL D 2 203 ? 90.027  86.104  105.203 1.00 36.52  ? 203  VAL B CG2   1 
ATOM   8638  N  N     . ILE D 2 204 ? 88.622  81.690  106.177 1.00 24.40  ? 204  ILE B N     1 
ATOM   8639  C  CA    . ILE D 2 204 ? 87.940  80.668  106.976 1.00 26.07  ? 204  ILE B CA    1 
ATOM   8640  C  C     . ILE D 2 204 ? 88.793  80.448  108.207 1.00 29.59  ? 204  ILE B C     1 
ATOM   8641  O  O     . ILE D 2 204 ? 89.911  79.933  108.126 1.00 32.79  ? 204  ILE B O     1 
ATOM   8642  C  CB    . ILE D 2 204 ? 87.805  79.367  106.207 1.00 29.26  ? 204  ILE B CB    1 
ATOM   8643  C  CG1   . ILE D 2 204 ? 87.038  79.643  104.908 1.00 31.21  ? 204  ILE B CG1   1 
ATOM   8644  C  CG2   . ILE D 2 204 ? 87.119  78.314  107.085 1.00 33.04  ? 204  ILE B CG2   1 
ATOM   8645  C  CD1   . ILE D 2 204 ? 87.246  78.610  103.814 1.00 14.85  ? 204  ILE B CD1   1 
ATOM   8646  N  N     . ARG D 2 205 ? 88.278  80.855  109.354 1.00 29.52  ? 205  ARG B N     1 
ATOM   8647  C  CA    . ARG D 2 205 ? 89.069  80.744  110.557 1.00 31.83  ? 205  ARG B CA    1 
ATOM   8648  C  C     . ARG D 2 205 ? 88.238  80.417  111.794 1.00 33.19  ? 205  ARG B C     1 
ATOM   8649  O  O     . ARG D 2 205 ? 87.008  80.466  111.778 1.00 34.00  ? 205  ARG B O     1 
ATOM   8650  C  CB    . ARG D 2 205 ? 89.816  82.060  110.767 1.00 32.57  ? 205  ARG B CB    1 
ATOM   8651  C  CG    . ARG D 2 205 ? 89.003  83.068  111.538 1.00 41.19  ? 205  ARG B CG    1 
ATOM   8652  C  CD    . ARG D 2 205 ? 88.779  84.398  110.861 1.00 38.21  ? 205  ARG B CD    1 
ATOM   8653  N  NE    . ARG D 2 205 ? 89.936  85.273  110.823 1.00 34.52  ? 205  ARG B NE    1 
ATOM   8654  C  CZ    . ARG D 2 205 ? 89.853  86.607  110.758 1.00 43.60  ? 205  ARG B CZ    1 
ATOM   8655  N  NH1   . ARG D 2 205 ? 88.673  87.218  110.753 1.00 29.79  ? 205  ARG B NH1   1 
ATOM   8656  N  NH2   . ARG D 2 205 ? 90.953  87.335  110.612 1.00 34.79  ? 205  ARG B NH2   1 
ATOM   8657  N  N     . ALA D 2 206 ? 88.932  80.091  112.877 1.00 34.74  ? 206  ALA B N     1 
ATOM   8658  C  CA    . ALA D 2 206 ? 88.257  79.766  114.122 1.00 35.02  ? 206  ALA B CA    1 
ATOM   8659  C  C     . ALA D 2 206 ? 87.446  80.946  114.729 1.00 28.95  ? 206  ALA B C     1 
ATOM   8660  O  O     . ALA D 2 206 ? 87.837  82.106  114.639 1.00 28.87  ? 206  ALA B O     1 
ATOM   8661  C  CB    . ALA D 2 206 ? 89.287  79.236  115.132 1.00 33.66  ? 206  ALA B CB    1 
ATOM   8662  N  N     . GLU D 2 207 ? 86.321  80.604  115.346 1.00 30.93  ? 207  GLU B N     1 
ATOM   8663  C  CA    . GLU D 2 207 ? 85.419  81.561  115.980 1.00 42.71  ? 207  GLU B CA    1 
ATOM   8664  C  C     . GLU D 2 207 ? 86.163  82.535  116.872 1.00 39.94  ? 207  GLU B C     1 
ATOM   8665  O  O     . GLU D 2 207 ? 85.724  83.654  117.044 1.00 36.94  ? 207  GLU B O     1 
ATOM   8666  C  CB    . GLU D 2 207 ? 84.379  80.852  116.859 1.00 37.50  ? 207  GLU B CB    1 
ATOM   8667  C  CG    . GLU D 2 207 ? 83.049  80.549  116.217 1.00 59.06  ? 207  GLU B CG    1 
ATOM   8668  C  CD    . GLU D 2 207 ? 81.932  80.413  117.248 1.00 57.45  ? 207  GLU B CD    1 
ATOM   8669  O  OE1   . GLU D 2 207 ? 81.379  81.450  117.683 1.00 62.39  ? 207  GLU B OE1   1 
ATOM   8670  O  OE2   . GLU D 2 207 ? 81.616  79.269  117.636 1.00 65.03  ? 207  GLU B OE2   1 
ATOM   8671  N  N     . GLU D 2 208 ? 87.289  82.122  117.435 1.00 31.15  ? 208  GLU B N     1 
ATOM   8672  C  CA    . GLU D 2 208 ? 87.972  83.031  118.328 1.00 40.15  ? 208  GLU B CA    1 
ATOM   8673  C  C     . GLU D 2 208 ? 88.353  84.349  117.692 1.00 42.06  ? 208  GLU B C     1 
ATOM   8674  O  O     . GLU D 2 208 ? 88.606  85.320  118.401 1.00 41.93  ? 208  GLU B O     1 
ATOM   8675  C  CB    . GLU D 2 208 ? 89.198  82.376  118.964 1.00 36.85  ? 208  GLU B CB    1 
ATOM   8676  C  CG    . GLU D 2 208 ? 90.163  81.731  118.018 1.00 56.08  ? 208  GLU B CG    1 
ATOM   8677  C  CD    . GLU D 2 208 ? 91.431  81.312  118.727 1.00 62.15  ? 208  GLU B CD    1 
ATOM   8678  O  OE1   . GLU D 2 208 ? 92.116  82.210  119.258 1.00 74.10  ? 208  GLU B OE1   1 
ATOM   8679  O  OE2   . GLU D 2 208 ? 91.740  80.098  118.770 1.00 68.82  ? 208  GLU B OE2   1 
ATOM   8680  N  N     . TRP D 2 209 ? 88.342  84.406  116.364 1.00 32.28  ? 209  TRP B N     1 
ATOM   8681  C  CA    . TRP D 2 209 ? 88.711  85.638  115.683 1.00 34.66  ? 209  TRP B CA    1 
ATOM   8682  C  C     . TRP D 2 209 ? 87.524  86.520  115.320 1.00 38.36  ? 209  TRP B C     1 
ATOM   8683  O  O     . TRP D 2 209 ? 87.707  87.617  114.777 1.00 37.77  ? 209  TRP B O     1 
ATOM   8684  C  CB    . TRP D 2 209 ? 89.483  85.322  114.394 1.00 37.86  ? 209  TRP B CB    1 
ATOM   8685  C  CG    . TRP D 2 209 ? 90.616  84.430  114.637 1.00 31.31  ? 209  TRP B CG    1 
ATOM   8686  C  CD1   . TRP D 2 209 ? 90.634  83.070  114.513 1.00 42.81  ? 209  TRP B CD1   1 
ATOM   8687  C  CD2   . TRP D 2 209 ? 91.860  84.799  115.211 1.00 34.56  ? 209  TRP B CD2   1 
ATOM   8688  N  NE1   . TRP D 2 209 ? 91.820  82.567  114.993 1.00 37.42  ? 209  TRP B NE1   1 
ATOM   8689  C  CE2   . TRP D 2 209 ? 92.590  83.611  115.429 1.00 39.03  ? 209  TRP B CE2   1 
ATOM   8690  C  CE3   . TRP D 2 209 ? 92.434  86.026  115.572 1.00 48.43  ? 209  TRP B CE3   1 
ATOM   8691  C  CZ2   . TRP D 2 209 ? 93.863  83.611  115.990 1.00 48.28  ? 209  TRP B CZ2   1 
ATOM   8692  C  CZ3   . TRP D 2 209 ? 93.707  86.029  116.130 1.00 49.61  ? 209  TRP B CZ3   1 
ATOM   8693  C  CH2   . TRP D 2 209 ? 94.406  84.828  116.333 1.00 50.01  ? 209  TRP B CH2   1 
ATOM   8694  N  N     . LEU D 2 210 ? 86.310  86.067  115.604 1.00 32.17  ? 210  LEU B N     1 
ATOM   8695  C  CA    . LEU D 2 210 ? 85.180  86.864  115.183 1.00 32.81  ? 210  LEU B CA    1 
ATOM   8696  C  C     . LEU D 2 210 ? 85.222  88.268  115.745 1.00 38.17  ? 210  LEU B C     1 
ATOM   8697  O  O     . LEU D 2 210 ? 85.108  89.230  114.993 1.00 38.04  ? 210  LEU B O     1 
ATOM   8698  C  CB    . LEU D 2 210 ? 83.857  86.185  115.541 1.00 31.71  ? 210  LEU B CB    1 
ATOM   8699  C  CG    . LEU D 2 210 ? 82.578  86.786  114.930 1.00 31.74  ? 210  LEU B CG    1 
ATOM   8700  C  CD1   . LEU D 2 210 ? 82.690  86.967  113.410 1.00 27.65  ? 210  LEU B CD1   1 
ATOM   8701  C  CD2   . LEU D 2 210 ? 81.421  85.862  115.264 1.00 31.10  ? 210  LEU B CD2   1 
ATOM   8702  N  N     . VAL D 2 211 ? 85.430  88.400  117.051 1.00 36.26  ? 211  VAL B N     1 
ATOM   8703  C  CA    . VAL D 2 211 ? 85.436  89.718  117.670 1.00 34.19  ? 211  VAL B CA    1 
ATOM   8704  C  C     . VAL D 2 211 ? 86.480  90.654  117.093 1.00 37.20  ? 211  VAL B C     1 
ATOM   8705  O  O     . VAL D 2 211 ? 86.373  91.866  117.231 1.00 35.04  ? 211  VAL B O     1 
ATOM   8706  C  CB    . VAL D 2 211 ? 85.615  89.623  119.199 1.00 41.90  ? 211  VAL B CB    1 
ATOM   8707  C  CG1   . VAL D 2 211 ? 85.834  91.003  119.792 1.00 51.48  ? 211  VAL B CG1   1 
ATOM   8708  C  CG2   . VAL D 2 211 ? 84.365  89.042  119.827 1.00 42.25  ? 211  VAL B CG2   1 
ATOM   8709  N  N     . SER D 2 212 ? 87.493  90.106  116.439 1.00 38.73  ? 212  SER B N     1 
ATOM   8710  C  CA    . SER D 2 212 ? 88.530  90.958  115.854 1.00 38.61  ? 212  SER B CA    1 
ATOM   8711  C  C     . SER D 2 212 ? 88.196  91.366  114.422 1.00 34.74  ? 212  SER B C     1 
ATOM   8712  O  O     . SER D 2 212 ? 88.781  92.294  113.879 1.00 36.69  ? 212  SER B O     1 
ATOM   8713  C  CB    . SER D 2 212 ? 89.885  90.247  115.863 1.00 30.75  ? 212  SER B CB    1 
ATOM   8714  O  OG    . SER D 2 212 ? 90.378  90.128  117.184 1.00 47.38  ? 212  SER B OG    1 
ATOM   8715  N  N     . THR D 2 213 ? 87.260  90.665  113.808 1.00 25.51  ? 213  THR B N     1 
ATOM   8716  C  CA    . THR D 2 213 ? 86.908  90.978  112.441 1.00 31.86  ? 213  THR B CA    1 
ATOM   8717  C  C     . THR D 2 213 ? 86.610  92.473  112.230 1.00 34.20  ? 213  THR B C     1 
ATOM   8718  O  O     . THR D 2 213 ? 87.094  93.047  111.260 1.00 30.23  ? 213  THR B O     1 
ATOM   8719  C  CB    . THR D 2 213 ? 85.723  90.072  111.944 1.00 23.23  ? 213  THR B CB    1 
ATOM   8720  O  OG1   . THR D 2 213 ? 86.102  88.690  112.074 1.00 23.10  ? 213  THR B OG1   1 
ATOM   8721  C  CG2   . THR D 2 213 ? 85.410  90.330  110.460 1.00 29.19  ? 213  THR B CG2   1 
ATOM   8722  N  N     . PRO D 2 214 ? 85.850  93.127  113.147 1.00 34.79  ? 214  PRO B N     1 
ATOM   8723  C  CA    . PRO D 2 214 ? 85.538  94.559  112.988 1.00 33.54  ? 214  PRO B CA    1 
ATOM   8724  C  C     . PRO D 2 214 ? 86.829  95.375  112.857 1.00 34.92  ? 214  PRO B C     1 
ATOM   8725  O  O     . PRO D 2 214 ? 86.878  96.372  112.144 1.00 38.78  ? 214  PRO B O     1 
ATOM   8726  C  CB    . PRO D 2 214 ? 84.786  94.923  114.274 1.00 34.84  ? 214  PRO B CB    1 
ATOM   8727  C  CG    . PRO D 2 214 ? 84.385  93.620  114.856 1.00 42.77  ? 214  PRO B CG    1 
ATOM   8728  C  CD    . PRO D 2 214 ? 85.466  92.665  114.489 1.00 36.86  ? 214  PRO B CD    1 
ATOM   8729  N  N     . ILE D 2 215 ? 87.866  94.959  113.564 1.00 27.51  ? 215  ILE B N     1 
ATOM   8730  C  CA    . ILE D 2 215 ? 89.139  95.642  113.458 1.00 35.23  ? 215  ILE B CA    1 
ATOM   8731  C  C     . ILE D 2 215 ? 89.639  95.517  112.016 1.00 38.46  ? 215  ILE B C     1 
ATOM   8732  O  O     . ILE D 2 215 ? 90.057  96.498  111.396 1.00 34.34  ? 215  ILE B O     1 
ATOM   8733  C  CB    . ILE D 2 215 ? 90.169  95.020  114.413 1.00 31.10  ? 215  ILE B CB    1 
ATOM   8734  C  CG1   . ILE D 2 215 ? 89.797  95.362  115.859 1.00 40.25  ? 215  ILE B CG1   1 
ATOM   8735  C  CG2   . ILE D 2 215 ? 91.561  95.524  114.092 1.00 36.13  ? 215  ILE B CG2   1 
ATOM   8736  C  CD1   . ILE D 2 215 ? 90.694  94.715  116.882 1.00 41.79  ? 215  ILE B CD1   1 
ATOM   8737  N  N     . HIS D 2 216 ? 89.572  94.308  111.479 1.00 32.11  ? 216  HIS B N     1 
ATOM   8738  C  CA    . HIS D 2 216 ? 90.031  94.052  110.120 1.00 36.82  ? 216  HIS B CA    1 
ATOM   8739  C  C     . HIS D 2 216 ? 89.144  94.720  109.079 1.00 37.78  ? 216  HIS B C     1 
ATOM   8740  O  O     . HIS D 2 216 ? 89.645  95.241  108.079 1.00 34.79  ? 216  HIS B O     1 
ATOM   8741  C  CB    . HIS D 2 216 ? 90.139  92.538  109.908 1.00 26.93  ? 216  HIS B CB    1 
ATOM   8742  C  CG    . HIS D 2 216 ? 90.947  91.871  110.976 1.00 28.25  ? 216  HIS B CG    1 
ATOM   8743  N  ND1   . HIS D 2 216 ? 90.729  90.578  111.394 1.00 29.28  ? 216  HIS B ND1   1 
ATOM   8744  C  CD2   . HIS D 2 216 ? 91.949  92.351  111.754 1.00 29.21  ? 216  HIS B CD2   1 
ATOM   8745  C  CE1   . HIS D 2 216 ? 91.560  90.290  112.382 1.00 30.96  ? 216  HIS B CE1   1 
ATOM   8746  N  NE2   . HIS D 2 216 ? 92.311  91.350  112.619 1.00 31.10  ? 216  HIS B NE2   1 
ATOM   8747  N  N     . VAL D 2 217 ? 87.840  94.727  109.320 1.00 33.26  ? 217  VAL B N     1 
ATOM   8748  C  CA    . VAL D 2 217 ? 86.909  95.379  108.409 1.00 34.69  ? 217  VAL B CA    1 
ATOM   8749  C  C     . VAL D 2 217 ? 87.289  96.853  108.263 1.00 38.57  ? 217  VAL B C     1 
ATOM   8750  O  O     . VAL D 2 217 ? 87.304  97.418  107.154 1.00 35.84  ? 217  VAL B O     1 
ATOM   8751  C  CB    . VAL D 2 217 ? 85.459  95.255  108.932 1.00 32.06  ? 217  VAL B CB    1 
ATOM   8752  C  CG1   . VAL D 2 217 ? 84.563  96.340  108.339 1.00 33.21  ? 217  VAL B CG1   1 
ATOM   8753  C  CG2   . VAL D 2 217 ? 84.926  93.923  108.540 1.00 29.10  ? 217  VAL B CG2   1 
ATOM   8754  N  N     . LEU D 2 218 ? 87.596  97.464  109.401 1.00 37.67  ? 218  LEU B N     1 
ATOM   8755  C  CA    . LEU D 2 218 ? 88.003  98.861  109.446 1.00 37.37  ? 218  LEU B CA    1 
ATOM   8756  C  C     . LEU D 2 218 ? 89.321  99.067  108.688 1.00 42.37  ? 218  LEU B C     1 
ATOM   8757  O  O     . LEU D 2 218 ? 89.458  100.040 107.955 1.00 46.11  ? 218  LEU B O     1 
ATOM   8758  C  CB    . LEU D 2 218 ? 88.145  99.313  110.909 1.00 34.07  ? 218  LEU B CB    1 
ATOM   8759  C  CG    . LEU D 2 218 ? 87.093  100.268 111.500 1.00 41.26  ? 218  LEU B CG    1 
ATOM   8760  C  CD1   . LEU D 2 218 ? 85.748  100.163 110.780 1.00 34.44  ? 218  LEU B CD1   1 
ATOM   8761  C  CD2   . LEU D 2 218 ? 86.950  99.957  112.981 1.00 31.04  ? 218  LEU B CD2   1 
ATOM   8762  N  N     . LEU D 2 219 ? 90.294  98.167  108.862 1.00 36.98  ? 219  LEU B N     1 
ATOM   8763  C  CA    . LEU D 2 219 ? 91.555  98.313  108.137 1.00 34.18  ? 219  LEU B CA    1 
ATOM   8764  C  C     . LEU D 2 219 ? 91.342  98.239  106.623 1.00 36.48  ? 219  LEU B C     1 
ATOM   8765  O  O     . LEU D 2 219 ? 91.956  98.995  105.881 1.00 39.30  ? 219  LEU B O     1 
ATOM   8766  C  CB    . LEU D 2 219 ? 92.559  97.249  108.562 1.00 32.26  ? 219  LEU B CB    1 
ATOM   8767  C  CG    . LEU D 2 219 ? 93.145  97.427  109.964 1.00 31.41  ? 219  LEU B CG    1 
ATOM   8768  C  CD1   . LEU D 2 219 ? 93.822  96.133  110.404 1.00 24.84  ? 219  LEU B CD1   1 
ATOM   8769  C  CD2   . LEU D 2 219 ? 94.095  98.601  109.977 1.00 18.63  ? 219  LEU B CD2   1 
ATOM   8770  N  N     . TYR D 2 220 ? 90.484  97.336  106.158 1.00 32.78  ? 220  TYR B N     1 
ATOM   8771  C  CA    . TYR D 2 220 ? 90.237  97.242  104.730 1.00 36.70  ? 220  TYR B CA    1 
ATOM   8772  C  C     . TYR D 2 220 ? 89.704  98.581  104.255 1.00 41.33  ? 220  TYR B C     1 
ATOM   8773  O  O     . TYR D 2 220 ? 90.131  99.081  103.218 1.00 45.90  ? 220  TYR B O     1 
ATOM   8774  C  CB    . TYR D 2 220 ? 89.227  96.134  104.389 1.00 37.62  ? 220  TYR B CB    1 
ATOM   8775  C  CG    . TYR D 2 220 ? 89.837  94.746  104.280 1.00 38.65  ? 220  TYR B CG    1 
ATOM   8776  C  CD1   . TYR D 2 220 ? 89.768  93.855  105.348 1.00 31.53  ? 220  TYR B CD1   1 
ATOM   8777  C  CD2   . TYR D 2 220 ? 90.531  94.349  103.125 1.00 33.15  ? 220  TYR B CD2   1 
ATOM   8778  C  CE1   . TYR D 2 220 ? 90.376  92.600  105.291 1.00 33.05  ? 220  TYR B CE1   1 
ATOM   8779  C  CE2   . TYR D 2 220 ? 91.152  93.090  103.056 1.00 36.39  ? 220  TYR B CE2   1 
ATOM   8780  C  CZ    . TYR D 2 220 ? 91.071  92.226  104.150 1.00 32.34  ? 220  TYR B CZ    1 
ATOM   8781  O  OH    . TYR D 2 220 ? 91.700  91.007  104.140 1.00 30.37  ? 220  TYR B OH    1 
ATOM   8782  N  N     . ARG D 2 221 ? 88.787  99.170  105.019 1.00 42.10  ? 221  ARG B N     1 
ATOM   8783  C  CA    . ARG D 2 221 ? 88.233  100.472 104.656 1.00 37.87  ? 221  ARG B CA    1 
ATOM   8784  C  C     . ARG D 2 221 ? 89.344  101.540 104.607 1.00 43.53  ? 221  ARG B C     1 
ATOM   8785  O  O     . ARG D 2 221 ? 89.478  102.261 103.620 1.00 38.77  ? 221  ARG B O     1 
ATOM   8786  C  CB    . ARG D 2 221 ? 87.152  100.908 105.657 1.00 42.77  ? 221  ARG B CB    1 
ATOM   8787  C  CG    . ARG D 2 221 ? 86.368  102.157 105.222 1.00 52.81  ? 221  ARG B CG    1 
ATOM   8788  C  CD    . ARG D 2 221 ? 85.422  102.669 106.309 1.00 52.89  ? 221  ARG B CD    1 
ATOM   8789  N  NE    . ARG D 2 221 ? 84.452  101.661 106.733 1.00 62.97  ? 221  ARG B NE    1 
ATOM   8790  C  CZ    . ARG D 2 221 ? 83.816  101.680 107.907 1.00 70.54  ? 221  ARG B CZ    1 
ATOM   8791  N  NH1   . ARG D 2 221 ? 84.041  102.659 108.781 1.00 62.81  ? 221  ARG B NH1   1 
ATOM   8792  N  NH2   . ARG D 2 221 ? 82.966  100.708 108.220 1.00 67.84  ? 221  ARG B NH2   1 
ATOM   8793  N  N     . ALA D 2 222 ? 90.139  101.637 105.669 1.00 36.96  ? 222  ALA B N     1 
ATOM   8794  C  CA    . ALA D 2 222 ? 91.213  102.617 105.718 1.00 42.23  ? 222  ALA B CA    1 
ATOM   8795  C  C     . ALA D 2 222 ? 92.138  102.530 104.496 1.00 48.97  ? 222  ALA B C     1 
ATOM   8796  O  O     . ALA D 2 222 ? 92.538  103.562 103.943 1.00 51.67  ? 222  ALA B O     1 
ATOM   8797  C  CB    . ALA D 2 222 ? 92.024  102.448 106.994 1.00 28.88  ? 222  ALA B CB    1 
ATOM   8798  N  N     . PHE D 2 223 ? 92.476  101.310 104.076 1.00 44.00  ? 223  PHE B N     1 
ATOM   8799  C  CA    . PHE D 2 223 ? 93.359  101.119 102.934 1.00 37.24  ? 223  PHE B CA    1 
ATOM   8800  C  C     . PHE D 2 223 ? 92.609  101.228 101.617 1.00 45.63  ? 223  PHE B C     1 
ATOM   8801  O  O     . PHE D 2 223 ? 93.222  101.285 100.556 1.00 50.93  ? 223  PHE B O     1 
ATOM   8802  C  CB    . PHE D 2 223 ? 94.034  99.755  102.998 1.00 36.37  ? 223  PHE B CB    1 
ATOM   8803  C  CG    . PHE D 2 223 ? 95.128  99.668  104.011 1.00 35.98  ? 223  PHE B CG    1 
ATOM   8804  C  CD1   . PHE D 2 223 ? 96.214  100.528 103.949 1.00 38.41  ? 223  PHE B CD1   1 
ATOM   8805  C  CD2   . PHE D 2 223 ? 95.096  98.701  105.003 1.00 29.07  ? 223  PHE B CD2   1 
ATOM   8806  C  CE1   . PHE D 2 223 ? 97.264  100.426 104.863 1.00 50.00  ? 223  PHE B CE1   1 
ATOM   8807  C  CE2   . PHE D 2 223 ? 96.125  98.593  105.908 1.00 41.17  ? 223  PHE B CE2   1 
ATOM   8808  C  CZ    . PHE D 2 223 ? 97.223  99.460  105.842 1.00 35.61  ? 223  PHE B CZ    1 
ATOM   8809  N  N     . GLY D 2 224 ? 91.286  101.252 101.676 1.00 37.22  ? 224  GLY B N     1 
ATOM   8810  C  CA    . GLY D 2 224 ? 90.526  101.364 100.451 1.00 30.55  ? 224  GLY B CA    1 
ATOM   8811  C  C     . GLY D 2 224 ? 90.421  100.054 99.699  1.00 40.15  ? 224  GLY B C     1 
ATOM   8812  O  O     . GLY D 2 224 ? 90.131  100.049 98.515  1.00 38.34  ? 224  GLY B O     1 
ATOM   8813  N  N     . TRP D 2 225 ? 90.660  98.936  100.382 1.00 41.90  ? 225  TRP B N     1 
ATOM   8814  C  CA    . TRP D 2 225 ? 90.564  97.626  99.742  1.00 36.94  ? 225  TRP B CA    1 
ATOM   8815  C  C     . TRP D 2 225 ? 89.215  96.950  99.999  1.00 40.16  ? 225  TRP B C     1 
ATOM   8816  O  O     . TRP D 2 225 ? 88.510  97.274  100.961 1.00 36.19  ? 225  TRP B O     1 
ATOM   8817  C  CB    . TRP D 2 225 ? 91.679  96.691  100.228 1.00 33.36  ? 225  TRP B CB    1 
ATOM   8818  C  CG    . TRP D 2 225 ? 93.059  97.224  100.049 1.00 36.38  ? 225  TRP B CG    1 
ATOM   8819  C  CD1   . TRP D 2 225 ? 93.480  98.070  99.074  1.00 36.64  ? 225  TRP B CD1   1 
ATOM   8820  C  CD2   . TRP D 2 225 ? 94.218  96.924  100.852 1.00 34.80  ? 225  TRP B CD2   1 
ATOM   8821  N  NE1   . TRP D 2 225 ? 94.825  98.318  99.217  1.00 43.58  ? 225  TRP B NE1   1 
ATOM   8822  C  CE2   . TRP D 2 225 ? 95.299  97.625  100.299 1.00 31.53  ? 225  TRP B CE2   1 
ATOM   8823  C  CE3   . TRP D 2 225 ? 94.440  96.126  101.980 1.00 31.30  ? 225  TRP B CE3   1 
ATOM   8824  C  CZ2   . TRP D 2 225 ? 96.582  97.560  100.831 1.00 41.28  ? 225  TRP B CZ2   1 
ATOM   8825  C  CZ3   . TRP D 2 225 ? 95.707  96.060  102.509 1.00 21.01  ? 225  TRP B CZ3   1 
ATOM   8826  C  CH2   . TRP D 2 225 ? 96.767  96.771  101.937 1.00 43.36  ? 225  TRP B CH2   1 
ATOM   8827  N  N     . GLU D 2 226 ? 88.882  96.006  99.119  1.00 43.64  ? 226  GLU B N     1 
ATOM   8828  C  CA    . GLU D 2 226 ? 87.656  95.217  99.190  1.00 44.14  ? 226  GLU B CA    1 
ATOM   8829  C  C     . GLU D 2 226 ? 87.896  94.111  100.231 1.00 37.65  ? 226  GLU B C     1 
ATOM   8830  O  O     . GLU D 2 226 ? 88.904  93.409  100.206 1.00 34.01  ? 226  GLU B O     1 
ATOM   8831  C  CB    . GLU D 2 226 ? 87.343  94.621  97.790  1.00 49.14  ? 226  GLU B CB    1 
ATOM   8832  C  CG    . GLU D 2 226 ? 86.115  93.677  97.697  1.00 57.02  ? 226  GLU B CG    1 
ATOM   8833  C  CD    . GLU D 2 226 ? 85.980  92.960  96.324  1.00 67.77  ? 226  GLU B CD    1 
ATOM   8834  O  OE1   . GLU D 2 226 ? 87.013  92.529  95.757  1.00 66.05  ? 226  GLU B OE1   1 
ATOM   8835  O  OE2   . GLU D 2 226 ? 84.839  92.809  95.820  1.00 52.72  ? 226  GLU B OE2   1 
ATOM   8836  N  N     . ALA D 2 227 ? 86.965  93.975  101.160 1.00 41.52  ? 227  ALA B N     1 
ATOM   8837  C  CA    . ALA D 2 227 ? 87.084  92.972  102.215 1.00 35.45  ? 227  ALA B CA    1 
ATOM   8838  C  C     . ALA D 2 227 ? 86.703  91.609  101.679 1.00 33.29  ? 227  ALA B C     1 
ATOM   8839  O  O     . ALA D 2 227 ? 85.839  91.483  100.828 1.00 32.03  ? 227  ALA B O     1 
ATOM   8840  C  CB    . ALA D 2 227 ? 86.175  93.341  103.396 1.00 31.28  ? 227  ALA B CB    1 
ATOM   8841  N  N     . PRO D 2 228 ? 87.367  90.565  102.161 1.00 31.97  ? 228  PRO B N     1 
ATOM   8842  C  CA    . PRO D 2 228 ? 87.042  89.217  101.691 1.00 25.93  ? 228  PRO B CA    1 
ATOM   8843  C  C     . PRO D 2 228 ? 85.810  88.686  102.409 1.00 33.44  ? 228  PRO B C     1 
ATOM   8844  O  O     . PRO D 2 228 ? 85.279  89.354  103.298 1.00 31.68  ? 228  PRO B O     1 
ATOM   8845  C  CB    . PRO D 2 228 ? 88.278  88.426  102.064 1.00 26.50  ? 228  PRO B CB    1 
ATOM   8846  C  CG    . PRO D 2 228 ? 88.749  89.136  103.339 1.00 27.06  ? 228  PRO B CG    1 
ATOM   8847  C  CD    . PRO D 2 228 ? 88.617  90.581  102.943 1.00 24.93  ? 228  PRO B CD    1 
ATOM   8848  N  N     . ARG D 2 229 ? 85.333  87.512  102.002 1.00 31.23  ? 229  ARG B N     1 
ATOM   8849  C  CA    . ARG D 2 229 ? 84.220  86.892  102.707 1.00 27.38  ? 229  ARG B CA    1 
ATOM   8850  C  C     . ARG D 2 229 ? 84.858  86.265  103.974 1.00 36.58  ? 229  ARG B C     1 
ATOM   8851  O  O     . ARG D 2 229 ? 86.019  85.824  103.946 1.00 27.92  ? 229  ARG B O     1 
ATOM   8852  C  CB    . ARG D 2 229 ? 83.593  85.784  101.870 1.00 31.58  ? 229  ARG B CB    1 
ATOM   8853  C  CG    . ARG D 2 229 ? 82.706  86.246  100.722 1.00 27.90  ? 229  ARG B CG    1 
ATOM   8854  C  CD    . ARG D 2 229 ? 82.219  85.052  99.894  1.00 34.34  ? 229  ARG B CD    1 
ATOM   8855  N  NE    . ARG D 2 229 ? 83.257  84.482  99.024  1.00 39.73  ? 229  ARG B NE    1 
ATOM   8856  C  CZ    . ARG D 2 229 ? 83.674  85.028  97.877  1.00 40.29  ? 229  ARG B CZ    1 
ATOM   8857  N  NH1   . ARG D 2 229 ? 83.145  86.162  97.446  1.00 55.38  ? 229  ARG B NH1   1 
ATOM   8858  N  NH2   . ARG D 2 229 ? 84.621  84.448  97.151  1.00 34.02  ? 229  ARG B NH2   1 
ATOM   8859  N  N     . PHE D 2 230 ? 84.103  86.236  105.073 1.00 32.85  ? 230  PHE B N     1 
ATOM   8860  C  CA    . PHE D 2 230 ? 84.558  85.655  106.333 1.00 30.06  ? 230  PHE B CA    1 
ATOM   8861  C  C     . PHE D 2 230 ? 83.654  84.458  106.726 1.00 39.39  ? 230  PHE B C     1 
ATOM   8862  O  O     . PHE D 2 230 ? 82.415  84.541  106.639 1.00 35.13  ? 230  PHE B O     1 
ATOM   8863  C  CB    . PHE D 2 230 ? 84.492  86.700  107.457 1.00 27.82  ? 230  PHE B CB    1 
ATOM   8864  C  CG    . PHE D 2 230 ? 85.423  87.855  107.280 1.00 23.02  ? 230  PHE B CG    1 
ATOM   8865  C  CD1   . PHE D 2 230 ? 86.784  87.720  107.548 1.00 27.43  ? 230  PHE B CD1   1 
ATOM   8866  C  CD2   . PHE D 2 230 ? 84.952  89.069  106.809 1.00 19.07  ? 230  PHE B CD2   1 
ATOM   8867  C  CE1   . PHE D 2 230 ? 87.676  88.783  107.339 1.00 25.44  ? 230  PHE B CE1   1 
ATOM   8868  C  CE2   . PHE D 2 230 ? 85.828  90.143  106.594 1.00 23.26  ? 230  PHE B CE2   1 
ATOM   8869  C  CZ    . PHE D 2 230 ? 87.195  89.996  106.857 1.00 27.95  ? 230  PHE B CZ    1 
ATOM   8870  N  N     . TYR D 2 231 ? 84.273  83.352  107.142 1.00 31.75  ? 231  TYR B N     1 
ATOM   8871  C  CA    . TYR D 2 231 ? 83.532  82.179  107.598 1.00 31.28  ? 231  TYR B CA    1 
ATOM   8872  C  C     . TYR D 2 231 ? 84.208  81.788  108.895 1.00 34.59  ? 231  TYR B C     1 
ATOM   8873  O  O     . TYR D 2 231 ? 85.361  81.344  108.897 1.00 34.90  ? 231  TYR B O     1 
ATOM   8874  C  CB    . TYR D 2 231 ? 83.645  81.012  106.628 1.00 31.55  ? 231  TYR B CB    1 
ATOM   8875  C  CG    . TYR D 2 231 ? 83.234  81.311  105.220 1.00 29.02  ? 231  TYR B CG    1 
ATOM   8876  C  CD1   . TYR D 2 231 ? 84.000  82.154  104.419 1.00 23.75  ? 231  TYR B CD1   1 
ATOM   8877  C  CD2   . TYR D 2 231 ? 82.109  80.704  104.657 1.00 33.25  ? 231  TYR B CD2   1 
ATOM   8878  C  CE1   . TYR D 2 231 ? 83.669  82.372  103.085 1.00 27.57  ? 231  TYR B CE1   1 
ATOM   8879  C  CE2   . TYR D 2 231 ? 81.764  80.929  103.317 1.00 21.11  ? 231  TYR B CE2   1 
ATOM   8880  C  CZ    . TYR D 2 231 ? 82.555  81.756  102.542 1.00 26.67  ? 231  TYR B CZ    1 
ATOM   8881  O  OH    . TYR D 2 231 ? 82.274  81.938  101.205 1.00 37.64  ? 231  TYR B OH    1 
ATOM   8882  N  N     . HIS D 2 232 ? 83.518  81.970  110.013 1.00 34.24  ? 232  HIS B N     1 
ATOM   8883  C  CA    . HIS D 2 232 ? 84.145  81.631  111.281 1.00 27.63  ? 232  HIS B CA    1 
ATOM   8884  C  C     . HIS D 2 232 ? 83.666  80.254  111.732 1.00 29.25  ? 232  HIS B C     1 
ATOM   8885  O  O     . HIS D 2 232 ? 82.462  79.993  111.865 1.00 27.82  ? 232  HIS B O     1 
ATOM   8886  C  CB    . HIS D 2 232 ? 83.885  82.749  112.316 1.00 25.27  ? 232  HIS B CB    1 
ATOM   8887  C  CG    . HIS D 2 232 ? 84.736  83.969  112.104 1.00 35.66  ? 232  HIS B CG    1 
ATOM   8888  N  ND1   . HIS D 2 232 ? 84.379  84.998  111.252 1.00 27.66  ? 232  HIS B ND1   1 
ATOM   8889  C  CD2   . HIS D 2 232 ? 85.988  84.267  112.543 1.00 34.44  ? 232  HIS B CD2   1 
ATOM   8890  C  CE1   . HIS D 2 232 ? 85.376  85.865  111.170 1.00 29.69  ? 232  HIS B CE1   1 
ATOM   8891  N  NE2   . HIS D 2 232 ? 86.364  85.444  111.943 1.00 25.04  ? 232  HIS B NE2   1 
ATOM   8892  N  N     . MET D 2 233 ? 84.621  79.358  111.912 1.00 25.80  ? 233  MET B N     1 
ATOM   8893  C  CA    . MET D 2 233 ? 84.314  77.988  112.315 1.00 35.09  ? 233  MET B CA    1 
ATOM   8894  C  C     . MET D 2 233 ? 84.305  77.867  113.824 1.00 32.80  ? 233  MET B C     1 
ATOM   8895  O  O     . MET D 2 233 ? 85.019  78.586  114.496 1.00 28.57  ? 233  MET B O     1 
ATOM   8896  C  CB    . MET D 2 233 ? 85.375  77.030  111.755 1.00 36.21  ? 233  MET B CB    1 
ATOM   8897  C  CG    . MET D 2 233 ? 85.443  76.979  110.245 1.00 39.92  ? 233  MET B CG    1 
ATOM   8898  S  SD    . MET D 2 233 ? 83.938  76.306  109.585 1.00 44.97  ? 233  MET B SD    1 
ATOM   8899  C  CE    . MET D 2 233 ? 84.216  74.494  109.845 1.00 45.38  ? 233  MET B CE    1 
ATOM   8900  N  N     . PRO D 2 234 ? 83.496  76.943  114.365 1.00 38.34  ? 234  PRO B N     1 
ATOM   8901  C  CA    . PRO D 2 234 ? 83.362  76.669  115.809 1.00 34.21  ? 234  PRO B CA    1 
ATOM   8902  C  C     . PRO D 2 234 ? 84.705  76.169  116.338 1.00 34.56  ? 234  PRO B C     1 
ATOM   8903  O  O     . PRO D 2 234 ? 85.500  75.602  115.586 1.00 32.40  ? 234  PRO B O     1 
ATOM   8904  C  CB    . PRO D 2 234 ? 82.318  75.552  115.871 1.00 30.68  ? 234  PRO B CB    1 
ATOM   8905  C  CG    . PRO D 2 234 ? 81.517  75.749  114.608 1.00 52.41  ? 234  PRO B CG    1 
ATOM   8906  C  CD    . PRO D 2 234 ? 82.574  76.101  113.576 1.00 44.49  ? 234  PRO B CD    1 
ATOM   8907  N  N     . LEU D 2 235 ? 84.954  76.382  117.625 1.00 34.56  ? 235  LEU B N     1 
ATOM   8908  C  CA    . LEU D 2 235 ? 86.197  75.943  118.253 1.00 34.02  ? 235  LEU B CA    1 
ATOM   8909  C  C     . LEU D 2 235 ? 86.044  74.507  118.770 1.00 40.21  ? 235  LEU B C     1 
ATOM   8910  O  O     . LEU D 2 235 ? 85.015  74.176  119.366 1.00 40.23  ? 235  LEU B O     1 
ATOM   8911  C  CB    . LEU D 2 235 ? 86.545  76.861  119.419 1.00 30.22  ? 235  LEU B CB    1 
ATOM   8912  C  CG    . LEU D 2 235 ? 87.293  78.146  119.085 1.00 43.71  ? 235  LEU B CG    1 
ATOM   8913  C  CD1   . LEU D 2 235 ? 87.312  79.092  120.289 1.00 40.84  ? 235  LEU B CD1   1 
ATOM   8914  C  CD2   . LEU D 2 235 ? 88.720  77.772  118.677 1.00 44.23  ? 235  LEU B CD2   1 
ATOM   8915  N  N     . LEU D 2 236 ? 87.046  73.661  118.524 1.00 31.50  ? 236  LEU B N     1 
ATOM   8916  C  CA    . LEU D 2 236 ? 87.015  72.289  119.012 1.00 33.34  ? 236  LEU B CA    1 
ATOM   8917  C  C     . LEU D 2 236 ? 87.059  72.464  120.528 1.00 28.34  ? 236  LEU B C     1 
ATOM   8918  O  O     . LEU D 2 236 ? 87.771  73.331  121.033 1.00 32.61  ? 236  LEU B O     1 
ATOM   8919  C  CB    . LEU D 2 236 ? 88.254  71.516  118.536 1.00 37.46  ? 236  LEU B CB    1 
ATOM   8920  C  CG    . LEU D 2 236 ? 88.259  70.681  117.236 1.00 43.73  ? 236  LEU B CG    1 
ATOM   8921  C  CD1   . LEU D 2 236 ? 87.232  71.097  116.228 1.00 28.04  ? 236  LEU B CD1   1 
ATOM   8922  C  CD2   . LEU D 2 236 ? 89.643  70.793  116.631 1.00 40.68  ? 236  LEU B CD2   1 
ATOM   8923  N  N     . ARG D 2 237 ? 86.343  71.616  121.247 1.00 24.87  ? 237  ARG B N     1 
ATOM   8924  C  CA    . ARG D 2 237 ? 86.260  71.711  122.702 1.00 29.69  ? 237  ARG B CA    1 
ATOM   8925  C  C     . ARG D 2 237 ? 86.809  70.507  123.456 1.00 32.09  ? 237  ARG B C     1 
ATOM   8926  O  O     . ARG D 2 237 ? 86.795  69.386  122.943 1.00 34.17  ? 237  ARG B O     1 
ATOM   8927  C  CB    . ARG D 2 237 ? 84.774  71.902  123.090 1.00 22.44  ? 237  ARG B CB    1 
ATOM   8928  C  CG    . ARG D 2 237 ? 83.994  72.863  122.132 1.00 17.47  ? 237  ARG B CG    1 
ATOM   8929  C  CD    . ARG D 2 237 ? 84.489  74.331  122.271 1.00 25.30  ? 237  ARG B CD    1 
ATOM   8930  N  NE    . ARG D 2 237 ? 83.539  75.068  123.098 1.00 46.34  ? 237  ARG B NE    1 
ATOM   8931  C  CZ    . ARG D 2 237 ? 82.565  75.840  122.627 1.00 43.63  ? 237  ARG B CZ    1 
ATOM   8932  N  NH1   . ARG D 2 237 ? 82.399  76.022  121.327 1.00 43.41  ? 237  ARG B NH1   1 
ATOM   8933  N  NH2   . ARG D 2 237 ? 81.705  76.386  123.467 1.00 71.03  ? 237  ARG B NH2   1 
ATOM   8934  N  N     . ASN D 2 238 ? 87.301  70.743  124.678 1.00 42.60  ? 238  ASN B N     1 
ATOM   8935  C  CA    . ASN D 2 238 ? 87.776  69.660  125.540 1.00 35.66  ? 238  ASN B CA    1 
ATOM   8936  C  C     . ASN D 2 238 ? 86.443  69.041  125.964 1.00 36.82  ? 238  ASN B C     1 
ATOM   8937  O  O     . ASN D 2 238 ? 85.395  69.635  125.748 1.00 35.38  ? 238  ASN B O     1 
ATOM   8938  C  CB    . ASN D 2 238 ? 88.492  70.192  126.782 1.00 28.24  ? 238  ASN B CB    1 
ATOM   8939  C  CG    . ASN D 2 238 ? 89.807  70.865  126.464 1.00 47.41  ? 238  ASN B CG    1 
ATOM   8940  O  OD1   . ASN D 2 238 ? 90.690  70.263  125.838 1.00 52.06  ? 238  ASN B OD1   1 
ATOM   8941  N  ND2   . ASN D 2 238 ? 89.965  72.119  126.911 1.00 37.03  ? 238  ASN B ND2   1 
ATOM   8942  N  N     . PRO D 2 239 ? 86.448  67.837  126.553 1.00 40.90  ? 239  PRO B N     1 
ATOM   8943  C  CA    . PRO D 2 239 ? 85.134  67.314  126.933 1.00 39.99  ? 239  PRO B CA    1 
ATOM   8944  C  C     . PRO D 2 239 ? 84.357  68.180  127.947 1.00 45.42  ? 239  PRO B C     1 
ATOM   8945  O  O     . PRO D 2 239 ? 83.126  68.066  128.016 1.00 42.95  ? 239  PRO B O     1 
ATOM   8946  C  CB    . PRO D 2 239 ? 85.443  65.901  127.423 1.00 43.05  ? 239  PRO B CB    1 
ATOM   8947  C  CG    . PRO D 2 239 ? 86.885  65.959  127.795 1.00 50.34  ? 239  PRO B CG    1 
ATOM   8948  C  CD    . PRO D 2 239 ? 87.486  66.815  126.724 1.00 45.03  ? 239  PRO B CD    1 
ATOM   8949  N  N     . ASP D 2 240 ? 85.042  69.054  128.705 1.00 37.91  ? 240  ASP B N     1 
ATOM   8950  C  CA    . ASP D 2 240 ? 84.325  69.944  129.630 1.00 37.67  ? 240  ASP B CA    1 
ATOM   8951  C  C     . ASP D 2 240 ? 83.806  71.183  128.899 1.00 41.45  ? 240  ASP B C     1 
ATOM   8952  O  O     . ASP D 2 240 ? 83.390  72.148  129.531 1.00 45.90  ? 240  ASP B O     1 
ATOM   8953  C  CB    . ASP D 2 240 ? 85.181  70.390  130.832 1.00 28.86  ? 240  ASP B CB    1 
ATOM   8954  C  CG    . ASP D 2 240 ? 86.287  71.376  130.461 1.00 51.29  ? 240  ASP B CG    1 
ATOM   8955  O  OD1   . ASP D 2 240 ? 86.190  72.052  129.398 1.00 53.71  ? 240  ASP B OD1   1 
ATOM   8956  O  OD2   . ASP D 2 240 ? 87.258  71.485  131.260 1.00 37.29  ? 240  ASP B OD2   1 
ATOM   8957  N  N     . LYS D 2 241 ? 83.853  71.143  127.566 1.00 46.39  ? 241  LYS B N     1 
ATOM   8958  C  CA    . LYS D 2 241 ? 83.374  72.218  126.684 1.00 39.05  ? 241  LYS B CA    1 
ATOM   8959  C  C     . LYS D 2 241 ? 84.263  73.469  126.472 1.00 39.49  ? 241  LYS B C     1 
ATOM   8960  O  O     . LYS D 2 241 ? 83.902  74.338  125.662 1.00 30.60  ? 241  LYS B O     1 
ATOM   8961  C  CB    . LYS D 2 241 ? 81.980  72.665  127.124 1.00 51.22  ? 241  LYS B CB    1 
ATOM   8962  C  CG    . LYS D 2 241 ? 80.995  71.532  127.343 1.00 58.16  ? 241  LYS B CG    1 
ATOM   8963  C  CD    . LYS D 2 241 ? 80.788  70.707  126.091 1.00 62.32  ? 241  LYS B CD    1 
ATOM   8964  C  CE    . LYS D 2 241 ? 79.784  69.578  126.331 1.00 60.08  ? 241  LYS B CE    1 
ATOM   8965  N  NZ    . LYS D 2 241 ? 78.358  70.047  126.270 1.00 64.76  ? 241  LYS B NZ    1 
ATOM   8966  N  N     . THR D 2 242 ? 85.391  73.589  127.183 1.00 32.43  ? 242  THR B N     1 
ATOM   8967  C  CA    . THR D 2 242 ? 86.255  74.744  126.957 1.00 34.27  ? 242  THR B CA    1 
ATOM   8968  C  C     . THR D 2 242 ? 87.064  74.459  125.691 1.00 36.33  ? 242  THR B C     1 
ATOM   8969  O  O     . THR D 2 242 ? 87.147  73.295  125.274 1.00 33.64  ? 242  THR B O     1 
ATOM   8970  C  CB    . THR D 2 242 ? 87.246  75.024  128.122 1.00 39.78  ? 242  THR B CB    1 
ATOM   8971  O  OG1   . THR D 2 242 ? 88.131  73.917  128.301 1.00 34.45  ? 242  THR B OG1   1 
ATOM   8972  C  CG2   . THR D 2 242 ? 86.479  75.338  129.420 1.00 43.71  ? 242  THR B CG2   1 
ATOM   8973  N  N     . LYS D 2 243 ? 87.646  75.490  125.063 1.00 30.43  ? 243  LYS B N     1 
ATOM   8974  C  CA    . LYS D 2 243 ? 88.394  75.215  123.849 1.00 37.18  ? 243  LYS B CA    1 
ATOM   8975  C  C     . LYS D 2 243 ? 89.527  74.228  124.136 1.00 40.69  ? 243  LYS B C     1 
ATOM   8976  O  O     . LYS D 2 243 ? 90.285  74.359  125.103 1.00 45.00  ? 243  LYS B O     1 
ATOM   8977  C  CB    . LYS D 2 243 ? 88.885  76.495  123.157 1.00 40.50  ? 243  LYS B CB    1 
ATOM   8978  C  CG    . LYS D 2 243 ? 89.721  77.438  123.971 1.00 38.44  ? 243  LYS B CG    1 
ATOM   8979  C  CD    . LYS D 2 243 ? 89.676  78.835  123.324 1.00 35.67  ? 243  LYS B CD    1 
ATOM   8980  C  CE    . LYS D 2 243 ? 90.618  78.976  122.140 1.00 51.64  ? 243  LYS B CE    1 
ATOM   8981  N  NZ    . LYS D 2 243 ? 92.030  79.257  122.588 1.00 48.93  ? 243  LYS B NZ    1 
ATOM   8982  N  N     . ILE D 2 244 ? 89.569  73.198  123.302 1.00 36.64  ? 244  ILE B N     1 
ATOM   8983  C  CA    . ILE D 2 244 ? 90.522  72.128  123.431 1.00 38.02  ? 244  ILE B CA    1 
ATOM   8984  C  C     . ILE D 2 244 ? 91.900  72.661  123.822 1.00 40.43  ? 244  ILE B C     1 
ATOM   8985  O  O     . ILE D 2 244 ? 92.385  73.649  123.251 1.00 36.63  ? 244  ILE B O     1 
ATOM   8986  C  CB    . ILE D 2 244 ? 90.536  71.329  122.119 1.00 35.89  ? 244  ILE B CB    1 
ATOM   8987  C  CG1   . ILE D 2 244 ? 91.317  70.041  122.291 1.00 26.16  ? 244  ILE B CG1   1 
ATOM   8988  C  CG2   . ILE D 2 244 ? 91.056  72.193  120.996 1.00 32.53  ? 244  ILE B CG2   1 
ATOM   8989  C  CD1   . ILE D 2 244 ? 90.861  68.986  121.293 1.00 31.82  ? 244  ILE B CD1   1 
ATOM   8990  N  N     . SER D 2 245 ? 92.510  72.021  124.821 1.00 39.50  ? 245  SER B N     1 
ATOM   8991  C  CA    . SER D 2 245 ? 93.827  72.440  125.314 1.00 47.08  ? 245  SER B CA    1 
ATOM   8992  C  C     . SER D 2 245 ? 94.684  71.251  125.700 1.00 45.02  ? 245  SER B C     1 
ATOM   8993  O  O     . SER D 2 245 ? 94.167  70.188  126.038 1.00 45.96  ? 245  SER B O     1 
ATOM   8994  C  CB    . SER D 2 245 ? 93.681  73.376  126.528 1.00 46.09  ? 245  SER B CB    1 
ATOM   8995  O  OG    . SER D 2 245 ? 92.995  72.734  127.599 1.00 50.16  ? 245  SER B OG    1 
ATOM   8996  N  N     . LYS D 2 246 ? 96.001  71.459  125.664 1.00 58.49  ? 246  LYS B N     1 
ATOM   8997  C  CA    . LYS D 2 246 ? 96.988  70.417  125.954 1.00 58.97  ? 246  LYS B CA    1 
ATOM   8998  C  C     . LYS D 2 246 ? 96.913  69.773  127.321 1.00 64.14  ? 246  LYS B C     1 
ATOM   8999  O  O     . LYS D 2 246 ? 97.432  68.675  127.506 1.00 66.77  ? 246  LYS B O     1 
ATOM   9000  C  CB    . LYS D 2 246 ? 98.403  70.949  125.758 1.00 60.96  ? 246  LYS B CB    1 
ATOM   9001  C  CG    . LYS D 2 246 ? 98.845  71.963  126.806 1.00 77.33  ? 246  LYS B CG    1 
ATOM   9002  C  CD    . LYS D 2 246 ? 100.273 72.469  126.535 1.00 89.49  ? 246  LYS B CD    1 
ATOM   9003  C  CE    . LYS D 2 246 ? 100.384 73.206  125.189 1.00 93.25  ? 246  LYS B CE    1 
ATOM   9004  N  NZ    . LYS D 2 246 ? 101.781 73.654  124.877 1.00 96.82  ? 246  LYS B NZ    1 
ATOM   9005  N  N     . ARG D 2 247 ? 96.280  70.440  128.277 1.00 65.82  ? 247  ARG B N     1 
ATOM   9006  C  CA    . ARG D 2 247 ? 96.168  69.893  129.626 1.00 69.97  ? 247  ARG B CA    1 
ATOM   9007  C  C     . ARG D 2 247 ? 94.932  69.025  129.820 1.00 66.45  ? 247  ARG B C     1 
ATOM   9008  O  O     . ARG D 2 247 ? 94.886  68.233  130.758 1.00 73.73  ? 247  ARG B O     1 
ATOM   9009  C  CB    . ARG D 2 247 ? 96.137  71.023  130.666 1.00 75.65  ? 247  ARG B CB    1 
ATOM   9010  C  CG    . ARG D 2 247 ? 97.305  71.987  130.569 1.00 89.96  ? 247  ARG B CG    1 
ATOM   9011  C  CD    . ARG D 2 247 ? 97.128  73.189  131.477 1.00 99.11  ? 247  ARG B CD    1 
ATOM   9012  N  NE    . ARG D 2 247 ? 97.184  72.843  132.897 1.00 101.26 ? 247  ARG B NE    1 
ATOM   9013  C  CZ    . ARG D 2 247 ? 97.145  73.737  133.886 1.00 105.65 ? 247  ARG B CZ    1 
ATOM   9014  N  NH1   . ARG D 2 247 ? 97.047  75.035  133.614 1.00 101.71 ? 247  ARG B NH1   1 
ATOM   9015  N  NH2   . ARG D 2 247 ? 97.205  73.336  135.150 1.00 106.91 ? 247  ARG B NH2   1 
ATOM   9016  N  N     . LYS D 2 248 ? 93.938  69.159  128.944 1.00 60.39  ? 248  LYS B N     1 
ATOM   9017  C  CA    . LYS D 2 248 ? 92.697  68.392  129.104 1.00 55.92  ? 248  LYS B CA    1 
ATOM   9018  C  C     . LYS D 2 248 ? 92.366  67.427  127.968 1.00 51.45  ? 248  LYS B C     1 
ATOM   9019  O  O     . LYS D 2 248 ? 91.446  66.611  128.078 1.00 56.59  ? 248  LYS B O     1 
ATOM   9020  C  CB    . LYS D 2 248 ? 91.515  69.348  129.302 1.00 52.36  ? 248  LYS B CB    1 
ATOM   9021  C  CG    . LYS D 2 248 ? 91.638  70.248  130.515 1.00 52.71  ? 248  LYS B CG    1 
ATOM   9022  C  CD    . LYS D 2 248 ? 90.536  71.287  130.519 1.00 62.41  ? 248  LYS B CD    1 
ATOM   9023  C  CE    . LYS D 2 248 ? 90.758  72.350  131.591 1.00 62.72  ? 248  LYS B CE    1 
ATOM   9024  N  NZ    . LYS D 2 248 ? 89.704  73.399  131.508 1.00 54.94  ? 248  LYS B NZ    1 
ATOM   9025  N  N     . SER D 2 249 ? 93.110  67.520  126.878 1.00 46.86  ? 249  SER B N     1 
ATOM   9026  C  CA    . SER D 2 249 ? 92.873  66.670  125.715 1.00 43.43  ? 249  SER B CA    1 
ATOM   9027  C  C     . SER D 2 249 ? 94.205  66.618  124.995 1.00 51.29  ? 249  SER B C     1 
ATOM   9028  O  O     . SER D 2 249 ? 95.128  67.359  125.365 1.00 56.42  ? 249  SER B O     1 
ATOM   9029  C  CB    . SER D 2 249 ? 91.851  67.329  124.783 1.00 29.19  ? 249  SER B CB    1 
ATOM   9030  O  OG    . SER D 2 249 ? 90.564  67.372  125.357 1.00 46.72  ? 249  SER B OG    1 
ATOM   9031  N  N     . HIS D 2 250 ? 94.313  65.780  123.968 1.00 35.08  ? 250  HIS B N     1 
ATOM   9032  C  CA    . HIS D 2 250 ? 95.557  65.731  123.214 1.00 38.00  ? 250  HIS B CA    1 
ATOM   9033  C  C     . HIS D 2 250 ? 95.359  66.623  122.015 1.00 31.25  ? 250  HIS B C     1 
ATOM   9034  O  O     . HIS D 2 250 ? 94.461  66.401  121.213 1.00 36.35  ? 250  HIS B O     1 
ATOM   9035  C  CB    . HIS D 2 250 ? 95.860  64.305  122.782 1.00 41.42  ? 250  HIS B CB    1 
ATOM   9036  C  CG    . HIS D 2 250 ? 95.983  63.362  123.929 1.00 34.77  ? 250  HIS B CG    1 
ATOM   9037  N  ND1   . HIS D 2 250 ? 97.121  63.283  124.703 1.00 46.00  ? 250  HIS B ND1   1 
ATOM   9038  C  CD2   . HIS D 2 250 ? 95.089  62.508  124.481 1.00 37.52  ? 250  HIS B CD2   1 
ATOM   9039  C  CE1   . HIS D 2 250 ? 96.923  62.419  125.683 1.00 38.96  ? 250  HIS B CE1   1 
ATOM   9040  N  NE2   . HIS D 2 250 ? 95.698  61.935  125.570 1.00 43.35  ? 250  HIS B NE2   1 
ATOM   9041  N  N     . THR D 2 251 ? 96.187  67.644  121.895 1.00 27.89  ? 251  THR B N     1 
ATOM   9042  C  CA    . THR D 2 251 ? 96.041  68.570  120.793 1.00 35.48  ? 251  THR B CA    1 
ATOM   9043  C  C     . THR D 2 251 ? 97.180  68.448  119.781 1.00 40.44  ? 251  THR B C     1 
ATOM   9044  O  O     . THR D 2 251 ? 97.097  69.012  118.692 1.00 45.69  ? 251  THR B O     1 
ATOM   9045  C  CB    . THR D 2 251 ? 95.964  70.028  121.315 1.00 34.67  ? 251  THR B CB    1 
ATOM   9046  O  OG1   . THR D 2 251 ? 97.171  70.348  122.014 1.00 34.85  ? 251  THR B OG1   1 
ATOM   9047  C  CG2   . THR D 2 251 ? 94.791  70.190  122.272 1.00 35.28  ? 251  THR B CG2   1 
ATOM   9048  N  N     . SER D 2 252 ? 98.233  67.718  120.139 1.00 31.28  ? 252  SER B N     1 
ATOM   9049  C  CA    . SER D 2 252 ? 99.372  67.531  119.251 1.00 25.13  ? 252  SER B CA    1 
ATOM   9050  C  C     . SER D 2 252 ? 99.119  66.433  118.232 1.00 25.59  ? 252  SER B C     1 
ATOM   9051  O  O     . SER D 2 252 ? 98.773  65.311  118.579 1.00 31.00  ? 252  SER B O     1 
ATOM   9052  C  CB    . SER D 2 252 ? 100.635 67.165  120.059 1.00 31.53  ? 252  SER B CB    1 
ATOM   9053  O  OG    . SER D 2 252 ? 101.759 66.886  119.210 1.00 37.95  ? 252  SER B OG    1 
ATOM   9054  N  N     . LEU D 2 253 ? 99.296  66.748  116.966 1.00 26.02  ? 253  LEU B N     1 
ATOM   9055  C  CA    . LEU D 2 253 ? 99.111  65.741  115.946 1.00 27.92  ? 253  LEU B CA    1 
ATOM   9056  C  C     . LEU D 2 253 ? 100.163 64.660  116.102 1.00 33.26  ? 253  LEU B C     1 
ATOM   9057  O  O     . LEU D 2 253 ? 99.918  63.525  115.707 1.00 36.92  ? 253  LEU B O     1 
ATOM   9058  C  CB    . LEU D 2 253 ? 99.225  66.358  114.559 1.00 29.94  ? 253  LEU B CB    1 
ATOM   9059  C  CG    . LEU D 2 253 ? 98.094  67.332  114.242 1.00 37.05  ? 253  LEU B CG    1 
ATOM   9060  C  CD1   . LEU D 2 253 ? 98.487  68.174  113.034 1.00 30.22  ? 253  LEU B CD1   1 
ATOM   9061  C  CD2   . LEU D 2 253 ? 96.788  66.551  114.016 1.00 23.43  ? 253  LEU B CD2   1 
ATOM   9062  N  N     . ASP D 2 254 ? 101.329 64.993  116.664 1.00 25.25  ? 254  ASP B N     1 
ATOM   9063  C  CA    . ASP D 2 254 ? 102.389 63.983  116.838 1.00 31.48  ? 254  ASP B CA    1 
ATOM   9064  C  C     . ASP D 2 254 ? 101.945 62.875  117.787 1.00 30.60  ? 254  ASP B C     1 
ATOM   9065  O  O     . ASP D 2 254 ? 102.330 61.711  117.618 1.00 33.60  ? 254  ASP B O     1 
ATOM   9066  C  CB    . ASP D 2 254 ? 103.684 64.607  117.367 1.00 36.86  ? 254  ASP B CB    1 
ATOM   9067  C  CG    . ASP D 2 254 ? 104.407 65.408  116.316 1.00 50.47  ? 254  ASP B CG    1 
ATOM   9068  O  OD1   . ASP D 2 254 ? 105.324 66.189  116.668 1.00 49.40  ? 254  ASP B OD1   1 
ATOM   9069  O  OD2   . ASP D 2 254 ? 104.054 65.249  115.125 1.00 62.09  ? 254  ASP B OD2   1 
ATOM   9070  N  N     . TRP D 2 255 ? 101.147 63.236  118.788 1.00 23.66  ? 255  TRP B N     1 
ATOM   9071  C  CA    . TRP D 2 255 ? 100.625 62.249  119.725 1.00 33.30  ? 255  TRP B CA    1 
ATOM   9072  C  C     . TRP D 2 255 ? 99.689  61.271  118.986 1.00 34.04  ? 255  TRP B C     1 
ATOM   9073  O  O     . TRP D 2 255 ? 99.776  60.060  119.195 1.00 44.99  ? 255  TRP B O     1 
ATOM   9074  C  CB    . TRP D 2 255 ? 99.865  62.932  120.882 1.00 31.58  ? 255  TRP B CB    1 
ATOM   9075  C  CG    . TRP D 2 255 ? 99.280  61.967  121.883 1.00 35.06  ? 255  TRP B CG    1 
ATOM   9076  C  CD1   . TRP D 2 255 ? 99.886  61.480  123.009 1.00 35.82  ? 255  TRP B CD1   1 
ATOM   9077  C  CD2   . TRP D 2 255 ? 98.003  61.318  121.804 1.00 37.68  ? 255  TRP B CD2   1 
ATOM   9078  N  NE1   . TRP D 2 255 ? 99.067  60.569  123.638 1.00 33.14  ? 255  TRP B NE1   1 
ATOM   9079  C  CE2   . TRP D 2 255 ? 97.906  60.446  122.920 1.00 42.69  ? 255  TRP B CE2   1 
ATOM   9080  C  CE3   . TRP D 2 255 ? 96.928  61.384  120.899 1.00 45.88  ? 255  TRP B CE3   1 
ATOM   9081  C  CZ2   . TRP D 2 255 ? 96.777  59.642  123.154 1.00 33.23  ? 255  TRP B CZ2   1 
ATOM   9082  C  CZ3   . TRP D 2 255 ? 95.794  60.585  121.137 1.00 38.43  ? 255  TRP B CZ3   1 
ATOM   9083  C  CH2   . TRP D 2 255 ? 95.735  59.725  122.257 1.00 41.65  ? 255  TRP B CH2   1 
ATOM   9084  N  N     . TYR D 2 256 ? 98.801  61.777  118.132 1.00 27.86  ? 256  TYR B N     1 
ATOM   9085  C  CA    . TYR D 2 256 ? 97.901  60.874  117.416 1.00 30.65  ? 256  TYR B CA    1 
ATOM   9086  C  C     . TYR D 2 256 ? 98.723  59.954  116.518 1.00 33.98  ? 256  TYR B C     1 
ATOM   9087  O  O     . TYR D 2 256 ? 98.480  58.743  116.462 1.00 36.33  ? 256  TYR B O     1 
ATOM   9088  C  CB    . TYR D 2 256 ? 96.869  61.640  116.582 1.00 21.32  ? 256  TYR B CB    1 
ATOM   9089  C  CG    . TYR D 2 256 ? 95.856  62.383  117.419 1.00 25.59  ? 256  TYR B CG    1 
ATOM   9090  C  CD1   . TYR D 2 256 ? 96.057  63.723  117.754 1.00 25.39  ? 256  TYR B CD1   1 
ATOM   9091  C  CD2   . TYR D 2 256 ? 94.753  61.722  117.966 1.00 20.62  ? 256  TYR B CD2   1 
ATOM   9092  C  CE1   . TYR D 2 256 ? 95.212  64.378  118.612 1.00 27.65  ? 256  TYR B CE1   1 
ATOM   9093  C  CE2   . TYR D 2 256 ? 93.893  62.371  118.839 1.00 24.64  ? 256  TYR B CE2   1 
ATOM   9094  C  CZ    . TYR D 2 256 ? 94.140  63.695  119.161 1.00 29.44  ? 256  TYR B CZ    1 
ATOM   9095  O  OH    . TYR D 2 256 ? 93.386  64.322  120.096 1.00 35.01  ? 256  TYR B OH    1 
ATOM   9096  N  N     . LYS D 2 257 ? 99.711  60.512  115.823 1.00 22.62  ? 257  LYS B N     1 
ATOM   9097  C  CA    . LYS D 2 257 ? 100.539 59.675  114.973 1.00 23.45  ? 257  LYS B CA    1 
ATOM   9098  C  C     . LYS D 2 257 ? 101.306 58.643  115.827 1.00 34.27  ? 257  LYS B C     1 
ATOM   9099  O  O     . LYS D 2 257 ? 101.399 57.474  115.449 1.00 33.75  ? 257  LYS B O     1 
ATOM   9100  C  CB    . LYS D 2 257 ? 101.506 60.532  114.165 1.00 18.47  ? 257  LYS B CB    1 
ATOM   9101  C  CG    . LYS D 2 257 ? 102.554 59.745  113.397 1.00 32.22  ? 257  LYS B CG    1 
ATOM   9102  C  CD    . LYS D 2 257 ? 103.284 60.651  112.412 1.00 38.43  ? 257  LYS B CD    1 
ATOM   9103  C  CE    . LYS D 2 257 ? 104.360 59.908  111.617 1.00 39.07  ? 257  LYS B CE    1 
ATOM   9104  N  NZ    . LYS D 2 257 ? 105.593 59.667  112.410 1.00 44.85  ? 257  LYS B NZ    1 
ATOM   9105  N  N     . ALA D 2 258 ? 101.820 59.057  116.988 1.00 27.49  ? 258  ALA B N     1 
ATOM   9106  C  CA    . ALA D 2 258 ? 102.575 58.136  117.847 1.00 35.27  ? 258  ALA B CA    1 
ATOM   9107  C  C     . ALA D 2 258 ? 101.696 57.053  118.476 1.00 32.71  ? 258  ALA B C     1 
ATOM   9108  O  O     . ALA D 2 258 ? 102.187 55.979  118.809 1.00 34.07  ? 258  ALA B O     1 
ATOM   9109  C  CB    . ALA D 2 258 ? 103.338 58.927  118.962 1.00 26.35  ? 258  ALA B CB    1 
ATOM   9110  N  N     . GLU D 2 259 ? 100.405 57.343  118.636 1.00 30.14  ? 259  GLU B N     1 
ATOM   9111  C  CA    . GLU D 2 259 ? 99.460  56.403  119.234 1.00 31.10  ? 259  GLU B CA    1 
ATOM   9112  C  C     . GLU D 2 259 ? 98.856  55.428  118.224 1.00 37.84  ? 259  GLU B C     1 
ATOM   9113  O  O     . GLU D 2 259 ? 97.997  54.610  118.565 1.00 36.54  ? 259  GLU B O     1 
ATOM   9114  C  CB    . GLU D 2 259 ? 98.333  57.168  119.927 1.00 42.14  ? 259  GLU B CB    1 
ATOM   9115  C  CG    . GLU D 2 259 ? 98.130  56.762  121.357 1.00 52.96  ? 259  GLU B CG    1 
ATOM   9116  C  CD    . GLU D 2 259 ? 99.429  56.799  122.124 1.00 59.28  ? 259  GLU B CD    1 
ATOM   9117  O  OE1   . GLU D 2 259 ? 100.190 57.780  121.957 1.00 66.77  ? 259  GLU B OE1   1 
ATOM   9118  O  OE2   . GLU D 2 259 ? 99.693  55.854  122.887 1.00 62.32  ? 259  GLU B OE2   1 
ATOM   9119  N  N     . GLY D 2 260 ? 99.283  55.541  116.974 1.00 35.43  ? 260  GLY B N     1 
ATOM   9120  C  CA    . GLY D 2 260 ? 98.801  54.636  115.958 1.00 32.87  ? 260  GLY B CA    1 
ATOM   9121  C  C     . GLY D 2 260 ? 97.465  54.945  115.317 1.00 29.83  ? 260  GLY B C     1 
ATOM   9122  O  O     . GLY D 2 260 ? 96.743  54.016  114.914 1.00 27.55  ? 260  GLY B O     1 
ATOM   9123  N  N     . PHE D 2 261 ? 97.118  56.225  115.232 1.00 22.69  ? 261  PHE B N     1 
ATOM   9124  C  CA    . PHE D 2 261 ? 95.886  56.626  114.569 1.00 22.97  ? 261  PHE B CA    1 
ATOM   9125  C  C     . PHE D 2 261 ? 96.296  56.878  113.115 1.00 28.04  ? 261  PHE B C     1 
ATOM   9126  O  O     . PHE D 2 261 ? 97.348  57.463  112.869 1.00 25.42  ? 261  PHE B O     1 
ATOM   9127  C  CB    . PHE D 2 261 ? 95.312  57.926  115.166 1.00 24.03  ? 261  PHE B CB    1 
ATOM   9128  C  CG    . PHE D 2 261 ? 94.546  57.726  116.437 1.00 26.96  ? 261  PHE B CG    1 
ATOM   9129  C  CD1   . PHE D 2 261 ? 95.188  57.799  117.674 1.00 27.32  ? 261  PHE B CD1   1 
ATOM   9130  C  CD2   . PHE D 2 261 ? 93.192  57.407  116.404 1.00 24.86  ? 261  PHE B CD2   1 
ATOM   9131  C  CE1   . PHE D 2 261 ? 94.500  57.551  118.855 1.00 16.98  ? 261  PHE B CE1   1 
ATOM   9132  C  CE2   . PHE D 2 261 ? 92.496  57.158  117.590 1.00 30.45  ? 261  PHE B CE2   1 
ATOM   9133  C  CZ    . PHE D 2 261 ? 93.158  57.230  118.816 1.00 19.51  ? 261  PHE B CZ    1 
ATOM   9134  N  N     . LEU D 2 262 ? 95.473  56.426  112.168 1.00 25.85  ? 262  LEU B N     1 
ATOM   9135  C  CA    . LEU D 2 262 ? 95.750  56.615  110.743 1.00 23.64  ? 262  LEU B CA    1 
ATOM   9136  C  C     . LEU D 2 262 ? 95.397  58.055  110.397 1.00 26.19  ? 262  LEU B C     1 
ATOM   9137  O  O     . LEU D 2 262 ? 94.391  58.581  110.862 1.00 21.76  ? 262  LEU B O     1 
ATOM   9138  C  CB    . LEU D 2 262 ? 94.888  55.675  109.912 1.00 20.38  ? 262  LEU B CB    1 
ATOM   9139  C  CG    . LEU D 2 262 ? 95.096  54.202  110.232 1.00 28.32  ? 262  LEU B CG    1 
ATOM   9140  C  CD1   . LEU D 2 262 ? 94.029  53.352  109.492 1.00 33.03  ? 262  LEU B CD1   1 
ATOM   9141  C  CD2   . LEU D 2 262 ? 96.498  53.820  109.823 1.00 28.60  ? 262  LEU B CD2   1 
ATOM   9142  N  N     . PRO D 2 263 ? 96.202  58.707  109.558 1.00 23.40  ? 263  PRO B N     1 
ATOM   9143  C  CA    . PRO D 2 263 ? 95.845  60.090  109.257 1.00 18.74  ? 263  PRO B CA    1 
ATOM   9144  C  C     . PRO D 2 263 ? 94.563  60.227  108.472 1.00 21.69  ? 263  PRO B C     1 
ATOM   9145  O  O     . PRO D 2 263 ? 93.899  61.275  108.523 1.00 23.93  ? 263  PRO B O     1 
ATOM   9146  C  CB    . PRO D 2 263 ? 97.079  60.618  108.519 1.00 16.42  ? 263  PRO B CB    1 
ATOM   9147  C  CG    . PRO D 2 263 ? 97.603  59.390  107.832 1.00 21.26  ? 263  PRO B CG    1 
ATOM   9148  C  CD    . PRO D 2 263 ? 97.464  58.324  108.901 1.00 23.51  ? 263  PRO B CD    1 
ATOM   9149  N  N     . GLU D 2 264 ? 94.201  59.173  107.763 1.00 18.52  ? 264  GLU B N     1 
ATOM   9150  C  CA    . GLU D 2 264 ? 92.986  59.215  106.984 1.00 24.35  ? 264  GLU B CA    1 
ATOM   9151  C  C     . GLU D 2 264 ? 91.799  59.170  107.915 1.00 27.89  ? 264  GLU B C     1 
ATOM   9152  O  O     . GLU D 2 264 ? 90.763  59.791  107.656 1.00 29.73  ? 264  GLU B O     1 
ATOM   9153  C  CB    . GLU D 2 264 ? 92.909  58.044  106.005 1.00 25.38  ? 264  GLU B CB    1 
ATOM   9154  C  CG    . GLU D 2 264 ? 93.987  58.060  104.922 1.00 33.51  ? 264  GLU B CG    1 
ATOM   9155  C  CD    . GLU D 2 264 ? 95.233  57.278  105.332 1.00 38.41  ? 264  GLU B CD    1 
ATOM   9156  O  OE1   . GLU D 2 264 ? 95.362  56.913  106.532 1.00 34.10  ? 264  GLU B OE1   1 
ATOM   9157  O  OE2   . GLU D 2 264 ? 96.080  57.035  104.452 1.00 35.47  ? 264  GLU B OE2   1 
ATOM   9158  N  N     . ALA D 2 265 ? 91.922  58.428  109.009 1.00 28.69  ? 265  ALA B N     1 
ATOM   9159  C  CA    . ALA D 2 265 ? 90.782  58.359  109.924 1.00 27.92  ? 265  ALA B CA    1 
ATOM   9160  C  C     . ALA D 2 265 ? 90.636  59.674  110.668 1.00 22.11  ? 265  ALA B C     1 
ATOM   9161  O  O     . ALA D 2 265 ? 89.536  60.186  110.773 1.00 14.89  ? 265  ALA B O     1 
ATOM   9162  C  CB    . ALA D 2 265 ? 90.944  57.231  110.893 1.00 25.04  ? 265  ALA B CB    1 
ATOM   9163  N  N     . LEU D 2 266 ? 91.763  60.219  111.140 1.00 18.18  ? 266  LEU B N     1 
ATOM   9164  C  CA    . LEU D 2 266 ? 91.792  61.475  111.895 1.00 24.82  ? 266  LEU B CA    1 
ATOM   9165  C  C     . LEU D 2 266 ? 91.204  62.613  111.074 1.00 23.77  ? 266  LEU B C     1 
ATOM   9166  O  O     . LEU D 2 266 ? 90.511  63.462  111.589 1.00 31.46  ? 266  LEU B O     1 
ATOM   9167  C  CB    . LEU D 2 266 ? 93.226  61.850  112.279 1.00 22.68  ? 266  LEU B CB    1 
ATOM   9168  C  CG    . LEU D 2 266 ? 93.459  62.710  113.532 1.00 29.67  ? 266  LEU B CG    1 
ATOM   9169  C  CD1   . LEU D 2 266 ? 94.685  63.578  113.353 1.00 25.27  ? 266  LEU B CD1   1 
ATOM   9170  C  CD2   . LEU D 2 266 ? 92.263  63.555  113.814 1.00 16.68  ? 266  LEU B CD2   1 
ATOM   9171  N  N     . ARG D 2 267 ? 91.525  62.621  109.790 1.00 31.54  ? 267  ARG B N     1 
ATOM   9172  C  CA    . ARG D 2 267 ? 91.064  63.623  108.859 1.00 20.10  ? 267  ARG B CA    1 
ATOM   9173  C  C     . ARG D 2 267 ? 89.571  63.437  108.668 1.00 26.43  ? 267  ARG B C     1 
ATOM   9174  O  O     . ARG D 2 267 ? 88.803  64.391  108.735 1.00 27.22  ? 267  ARG B O     1 
ATOM   9175  C  CB    . ARG D 2 267 ? 91.792  63.447  107.536 1.00 26.27  ? 267  ARG B CB    1 
ATOM   9176  C  CG    . ARG D 2 267 ? 91.277  64.280  106.396 1.00 33.65  ? 267  ARG B CG    1 
ATOM   9177  C  CD    . ARG D 2 267 ? 90.975  63.351  105.227 1.00 50.07  ? 267  ARG B CD    1 
ATOM   9178  N  NE    . ARG D 2 267 ? 89.592  62.891  105.230 1.00 48.50  ? 267  ARG B NE    1 
ATOM   9179  C  CZ    . ARG D 2 267 ? 89.192  61.681  104.855 1.00 44.67  ? 267  ARG B CZ    1 
ATOM   9180  N  NH1   . ARG D 2 267 ? 90.060  60.771  104.448 1.00 36.40  ? 267  ARG B NH1   1 
ATOM   9181  N  NH2   . ARG D 2 267 ? 87.904  61.397  104.862 1.00 46.77  ? 267  ARG B NH2   1 
ATOM   9182  N  N     . ASN D 2 268 ? 89.165  62.200  108.442 1.00 19.96  ? 268  ASN B N     1 
ATOM   9183  C  CA    . ASN D 2 268 ? 87.762  61.902  108.258 1.00 23.93  ? 268  ASN B CA    1 
ATOM   9184  C  C     . ASN D 2 268 ? 86.993  62.352  109.512 1.00 25.18  ? 268  ASN B C     1 
ATOM   9185  O  O     . ASN D 2 268 ? 85.921  62.921  109.408 1.00 22.31  ? 268  ASN B O     1 
ATOM   9186  C  CB    . ASN D 2 268 ? 87.609  60.394  107.996 1.00 24.78  ? 268  ASN B CB    1 
ATOM   9187  C  CG    . ASN D 2 268 ? 86.177  59.976  107.628 1.00 17.01  ? 268  ASN B CG    1 
ATOM   9188  O  OD1   . ASN D 2 268 ? 85.977  58.932  107.018 1.00 22.93  ? 268  ASN B OD1   1 
ATOM   9189  N  ND2   . ASN D 2 268 ? 85.191  60.782  107.999 1.00 24.14  ? 268  ASN B ND2   1 
ATOM   9190  N  N     . TYR D 2 269 ? 87.560  62.132  110.693 1.00 25.65  ? 269  TYR B N     1 
ATOM   9191  C  CA    . TYR D 2 269 ? 86.883  62.518  111.925 1.00 25.89  ? 269  TYR B CA    1 
ATOM   9192  C  C     . TYR D 2 269 ? 86.745  64.053  112.030 1.00 32.31  ? 269  TYR B C     1 
ATOM   9193  O  O     . TYR D 2 269 ? 85.673  64.592  112.372 1.00 27.83  ? 269  TYR B O     1 
ATOM   9194  C  CB    . TYR D 2 269 ? 87.630  61.957  113.139 1.00 29.10  ? 269  TYR B CB    1 
ATOM   9195  C  CG    . TYR D 2 269 ? 86.918  62.254  114.431 1.00 31.83  ? 269  TYR B CG    1 
ATOM   9196  C  CD1   . TYR D 2 269 ? 85.671  61.691  114.713 1.00 33.44  ? 269  TYR B CD1   1 
ATOM   9197  C  CD2   . TYR D 2 269 ? 87.440  63.170  115.328 1.00 33.10  ? 269  TYR B CD2   1 
ATOM   9198  C  CE1   . TYR D 2 269 ? 84.944  62.047  115.875 1.00 32.46  ? 269  TYR B CE1   1 
ATOM   9199  C  CE2   . TYR D 2 269 ? 86.737  63.533  116.469 1.00 39.94  ? 269  TYR B CE2   1 
ATOM   9200  C  CZ    . TYR D 2 269 ? 85.492  62.977  116.747 1.00 43.03  ? 269  TYR B CZ    1 
ATOM   9201  O  OH    . TYR D 2 269 ? 84.815  63.379  117.895 1.00 39.19  ? 269  TYR B OH    1 
ATOM   9202  N  N     . LEU D 2 270 ? 87.823  64.768  111.735 1.00 24.27  ? 270  LEU B N     1 
ATOM   9203  C  CA    . LEU D 2 270 ? 87.743  66.224  111.773 1.00 29.68  ? 270  LEU B CA    1 
ATOM   9204  C  C     . LEU D 2 270 ? 86.626  66.706  110.814 1.00 24.11  ? 270  LEU B C     1 
ATOM   9205  O  O     . LEU D 2 270 ? 85.929  67.671  111.095 1.00 26.79  ? 270  LEU B O     1 
ATOM   9206  C  CB    . LEU D 2 270 ? 89.095  66.826  111.382 1.00 26.00  ? 270  LEU B CB    1 
ATOM   9207  C  CG    . LEU D 2 270 ? 90.039  67.400  112.449 1.00 34.19  ? 270  LEU B CG    1 
ATOM   9208  C  CD1   . LEU D 2 270 ? 89.676  66.938  113.831 1.00 34.95  ? 270  LEU B CD1   1 
ATOM   9209  C  CD2   . LEU D 2 270 ? 91.454  67.017  112.106 1.00 26.17  ? 270  LEU B CD2   1 
ATOM   9210  N  N     . CYS D 2 271 ? 86.449  66.023  109.688 1.00 26.28  ? 271  CYS B N     1 
ATOM   9211  C  CA    . CYS D 2 271 ? 85.422  66.405  108.731 1.00 29.60  ? 271  CYS B CA    1 
ATOM   9212  C  C     . CYS D 2 271 ? 84.052  66.409  109.418 1.00 33.75  ? 271  CYS B C     1 
ATOM   9213  O  O     . CYS D 2 271 ? 83.225  67.258  109.136 1.00 30.96  ? 271  CYS B O     1 
ATOM   9214  C  CB    . CYS D 2 271 ? 85.365  65.417  107.559 1.00 31.71  ? 271  CYS B CB    1 
ATOM   9215  S  SG    . CYS D 2 271 ? 86.559  65.637  106.263 1.00 38.90  ? 271  CYS B SG    1 
ATOM   9216  N  N     . LEU D 2 272 ? 83.813  65.445  110.306 1.00 31.26  ? 272  LEU B N     1 
ATOM   9217  C  CA    . LEU D 2 272 ? 82.534  65.370  110.999 1.00 29.18  ? 272  LEU B CA    1 
ATOM   9218  C  C     . LEU D 2 272 ? 82.380  66.400  112.104 1.00 30.98  ? 272  LEU B C     1 
ATOM   9219  O  O     . LEU D 2 272 ? 81.314  66.516  112.687 1.00 32.15  ? 272  LEU B O     1 
ATOM   9220  C  CB    . LEU D 2 272 ? 82.326  63.971  111.566 1.00 32.90  ? 272  LEU B CB    1 
ATOM   9221  C  CG    . LEU D 2 272 ? 81.321  63.017  110.892 1.00 36.95  ? 272  LEU B CG    1 
ATOM   9222  C  CD1   . LEU D 2 272 ? 80.952  63.400  109.454 1.00 26.85  ? 272  LEU B CD1   1 
ATOM   9223  C  CD2   . LEU D 2 272 ? 81.936  61.632  110.955 1.00 35.09  ? 272  LEU B CD2   1 
ATOM   9224  N  N     . MET D 2 273 ? 83.454  67.122  112.413 1.00 34.02  ? 273  MET B N     1 
ATOM   9225  C  CA    . MET D 2 273 ? 83.403  68.184  113.421 1.00 36.54  ? 273  MET B CA    1 
ATOM   9226  C  C     . MET D 2 273 ? 82.859  69.420  112.685 1.00 36.49  ? 273  MET B C     1 
ATOM   9227  O  O     . MET D 2 273 ? 83.625  70.231  112.151 1.00 44.67  ? 273  MET B O     1 
ATOM   9228  C  CB    . MET D 2 273 ? 84.803  68.526  113.957 1.00 29.88  ? 273  MET B CB    1 
ATOM   9229  C  CG    . MET D 2 273 ? 85.543  67.404  114.651 1.00 34.31  ? 273  MET B CG    1 
ATOM   9230  S  SD    . MET D 2 273 ? 84.882  67.020  116.264 1.00 39.35  ? 273  MET B SD    1 
ATOM   9231  C  CE    . MET D 2 273 ? 83.860  65.665  115.871 1.00 29.42  ? 273  MET B CE    1 
ATOM   9232  N  N     . GLY D 2 274 ? 81.544  69.546  112.621 1.00 31.23  ? 274  GLY B N     1 
ATOM   9233  C  CA    . GLY D 2 274 ? 80.956  70.692  111.965 1.00 33.43  ? 274  GLY B CA    1 
ATOM   9234  C  C     . GLY D 2 274 ? 80.310  70.399  110.641 1.00 32.17  ? 274  GLY B C     1 
ATOM   9235  O  O     . GLY D 2 274 ? 79.451  71.140  110.206 1.00 49.66  ? 274  GLY B O     1 
ATOM   9236  N  N     . PHE D 2 275 ? 80.712  69.335  109.972 1.00 35.85  ? 275  PHE B N     1 
ATOM   9237  C  CA    . PHE D 2 275 ? 80.097  69.023  108.692 1.00 31.32  ? 275  PHE B CA    1 
ATOM   9238  C  C     . PHE D 2 275 ? 79.561  67.598  108.716 1.00 35.92  ? 275  PHE B C     1 
ATOM   9239  O  O     . PHE D 2 275 ? 80.027  66.763  109.487 1.00 37.15  ? 275  PHE B O     1 
ATOM   9240  C  CB    . PHE D 2 275 ? 81.122  69.206  107.571 1.00 33.10  ? 275  PHE B CB    1 
ATOM   9241  C  CG    . PHE D 2 275 ? 80.690  68.661  106.240 1.00 27.89  ? 275  PHE B CG    1 
ATOM   9242  C  CD1   . PHE D 2 275 ? 80.810  67.303  105.958 1.00 20.40  ? 275  PHE B CD1   1 
ATOM   9243  C  CD2   . PHE D 2 275 ? 80.115  69.503  105.286 1.00 32.70  ? 275  PHE B CD2   1 
ATOM   9244  C  CE1   . PHE D 2 275 ? 80.358  66.785  104.757 1.00 26.83  ? 275  PHE B CE1   1 
ATOM   9245  C  CE2   . PHE D 2 275 ? 79.653  68.993  104.069 1.00 39.31  ? 275  PHE B CE2   1 
ATOM   9246  C  CZ    . PHE D 2 275 ? 79.771  67.634  103.807 1.00 26.83  ? 275  PHE B CZ    1 
ATOM   9247  N  N     . SER D 2 276 ? 78.579  67.338  107.864 1.00 33.64  ? 276  SER B N     1 
ATOM   9248  C  CA    . SER D 2 276 ? 77.975  66.021  107.751 1.00 38.22  ? 276  SER B CA    1 
ATOM   9249  C  C     . SER D 2 276 ? 77.527  65.833  106.307 1.00 31.89  ? 276  SER B C     1 
ATOM   9250  O  O     . SER D 2 276 ? 77.264  66.803  105.613 1.00 44.67  ? 276  SER B O     1 
ATOM   9251  C  CB    . SER D 2 276 ? 76.761  65.910  108.681 1.00 33.86  ? 276  SER B CB    1 
ATOM   9252  O  OG    . SER D 2 276 ? 75.768  66.849  108.310 1.00 42.91  ? 276  SER B OG    1 
ATOM   9253  N  N     . MET D 2 277 ? 77.445  64.588  105.863 1.00 32.47  ? 277  MET B N     1 
ATOM   9254  C  CA    . MET D 2 277 ? 77.013  64.268  104.506 1.00 42.00  ? 277  MET B CA    1 
ATOM   9255  C  C     . MET D 2 277 ? 75.497  64.230  104.437 1.00 46.23  ? 277  MET B C     1 
ATOM   9256  O  O     . MET D 2 277 ? 74.817  63.934  105.434 1.00 45.38  ? 277  MET B O     1 
ATOM   9257  C  CB    . MET D 2 277 ? 77.549  62.897  104.090 1.00 38.01  ? 277  MET B CB    1 
ATOM   9258  C  CG    . MET D 2 277 ? 79.048  62.854  103.885 1.00 45.62  ? 277  MET B CG    1 
ATOM   9259  S  SD    . MET D 2 277 ? 79.500  63.541  102.289 1.00 50.37  ? 277  MET B SD    1 
ATOM   9260  C  CE    . MET D 2 277 ? 81.254  63.306  102.306 1.00 44.20  ? 277  MET B CE    1 
ATOM   9261  N  N     . PRO D 2 278 ? 74.937  64.520  103.254 1.00 50.74  ? 278  PRO B N     1 
ATOM   9262  C  CA    . PRO D 2 278 ? 73.477  64.506  103.079 1.00 52.42  ? 278  PRO B CA    1 
ATOM   9263  C  C     . PRO D 2 278 ? 72.860  63.144  103.417 1.00 50.13  ? 278  PRO B C     1 
ATOM   9264  O  O     . PRO D 2 278 ? 71.859  63.070  104.136 1.00 43.15  ? 278  PRO B O     1 
ATOM   9265  C  CB    . PRO D 2 278 ? 73.298  64.910  101.614 1.00 50.11  ? 278  PRO B CB    1 
ATOM   9266  C  CG    . PRO D 2 278 ? 74.609  64.459  100.977 1.00 65.84  ? 278  PRO B CG    1 
ATOM   9267  C  CD    . PRO D 2 278 ? 75.620  64.879  102.001 1.00 57.37  ? 278  PRO B CD    1 
ATOM   9268  N  N     . ASP D 2 279 ? 73.462  62.061  102.933 1.00 48.49  ? 279  ASP B N     1 
ATOM   9269  C  CA    . ASP D 2 279 ? 72.900  60.753  103.245 1.00 47.24  ? 279  ASP B CA    1 
ATOM   9270  C  C     . ASP D 2 279 ? 73.408  60.154  104.563 1.00 47.59  ? 279  ASP B C     1 
ATOM   9271  O  O     . ASP D 2 279 ? 73.306  58.952  104.786 1.00 49.22  ? 279  ASP B O     1 
ATOM   9272  C  CB    . ASP D 2 279 ? 73.129  59.778  102.092 1.00 47.97  ? 279  ASP B CB    1 
ATOM   9273  C  CG    . ASP D 2 279 ? 74.587  59.470  101.877 1.00 62.04  ? 279  ASP B CG    1 
ATOM   9274  O  OD1   . ASP D 2 279 ? 74.909  58.828  100.839 1.00 51.70  ? 279  ASP B OD1   1 
ATOM   9275  O  OD2   . ASP D 2 279 ? 75.396  59.869  102.754 1.00 51.03  ? 279  ASP B OD2   1 
ATOM   9276  N  N     . GLY D 2 280 ? 73.954  60.992  105.436 1.00 43.31  ? 280  GLY B N     1 
ATOM   9277  C  CA    . GLY D 2 280 ? 74.402  60.521  106.734 1.00 29.69  ? 280  GLY B CA    1 
ATOM   9278  C  C     . GLY D 2 280 ? 75.592  59.588  106.801 1.00 34.55  ? 280  GLY B C     1 
ATOM   9279  O  O     . GLY D 2 280 ? 75.949  59.159  107.895 1.00 39.26  ? 280  GLY B O     1 
ATOM   9280  N  N     . ARG D 2 281 ? 76.232  59.273  105.684 1.00 32.83  ? 281  ARG B N     1 
ATOM   9281  C  CA    . ARG D 2 281 ? 77.391  58.367  105.763 1.00 42.59  ? 281  ARG B CA    1 
ATOM   9282  C  C     . ARG D 2 281 ? 78.548  59.013  106.554 1.00 36.32  ? 281  ARG B C     1 
ATOM   9283  O  O     . ARG D 2 281 ? 78.793  60.208  106.437 1.00 45.69  ? 281  ARG B O     1 
ATOM   9284  C  CB    . ARG D 2 281 ? 77.871  57.979  104.369 1.00 27.05  ? 281  ARG B CB    1 
ATOM   9285  C  CG    . ARG D 2 281 ? 78.485  59.116  103.637 1.00 42.18  ? 281  ARG B CG    1 
ATOM   9286  C  CD    . ARG D 2 281 ? 79.267  58.638  102.436 1.00 55.26  ? 281  ARG B CD    1 
ATOM   9287  N  NE    . ARG D 2 281 ? 78.430  58.133  101.358 1.00 64.64  ? 281  ARG B NE    1 
ATOM   9288  C  CZ    . ARG D 2 281 ? 78.547  58.530  100.091 1.00 80.57  ? 281  ARG B CZ    1 
ATOM   9289  N  NH1   . ARG D 2 281 ? 79.463  59.442  99.768  1.00 73.42  ? 281  ARG B NH1   1 
ATOM   9290  N  NH2   . ARG D 2 281 ? 77.769  58.001  99.145  1.00 74.42  ? 281  ARG B NH2   1 
ATOM   9291  N  N     . GLU D 2 282 ? 79.256  58.223  107.352 1.00 35.90  ? 282  GLU B N     1 
ATOM   9292  C  CA    . GLU D 2 282 ? 80.355  58.741  108.171 1.00 37.33  ? 282  GLU B CA    1 
ATOM   9293  C  C     . GLU D 2 282 ? 81.767  58.443  107.696 1.00 35.60  ? 282  GLU B C     1 
ATOM   9294  O  O     . GLU D 2 282 ? 82.723  59.122  108.090 1.00 34.07  ? 282  GLU B O     1 
ATOM   9295  C  CB    . GLU D 2 282 ? 80.207  58.242  109.601 1.00 34.73  ? 282  GLU B CB    1 
ATOM   9296  C  CG    . GLU D 2 282 ? 78.995  58.818  110.263 1.00 46.93  ? 282  GLU B CG    1 
ATOM   9297  C  CD    . GLU D 2 282 ? 78.787  58.261  111.630 1.00 58.75  ? 282  GLU B CD    1 
ATOM   9298  O  OE1   . GLU D 2 282 ? 78.667  57.015  111.732 1.00 56.78  ? 282  GLU B OE1   1 
ATOM   9299  O  OE2   . GLU D 2 282 ? 78.743  59.068  112.590 1.00 61.41  ? 282  GLU B OE2   1 
ATOM   9300  N  N     . ILE D 2 283 ? 81.896  57.429  106.853 1.00 32.05  ? 283  ILE B N     1 
ATOM   9301  C  CA    . ILE D 2 283 ? 83.193  57.043  106.327 1.00 28.07  ? 283  ILE B CA    1 
ATOM   9302  C  C     . ILE D 2 283 ? 83.278  57.440  104.868 1.00 29.59  ? 283  ILE B C     1 
ATOM   9303  O  O     . ILE D 2 283 ? 82.495  56.986  104.045 1.00 33.45  ? 283  ILE B O     1 
ATOM   9304  C  CB    . ILE D 2 283 ? 83.391  55.534  106.463 1.00 26.66  ? 283  ILE B CB    1 
ATOM   9305  C  CG1   . ILE D 2 283 ? 83.222  55.130  107.942 1.00 16.94  ? 283  ILE B CG1   1 
ATOM   9306  C  CG2   . ILE D 2 283 ? 84.741  55.146  105.908 1.00 22.09  ? 283  ILE B CG2   1 
ATOM   9307  C  CD1   . ILE D 2 283 ? 83.958  56.051  108.921 1.00 21.44  ? 283  ILE B CD1   1 
ATOM   9308  N  N     . PHE D 2 284 ? 84.216  58.323  104.553 1.00 29.61  ? 284  PHE B N     1 
ATOM   9309  C  CA    . PHE D 2 284 ? 84.390  58.791  103.181 1.00 24.24  ? 284  PHE B CA    1 
ATOM   9310  C  C     . PHE D 2 284 ? 85.758  59.400  103.049 1.00 27.19  ? 284  PHE B C     1 
ATOM   9311  O  O     . PHE D 2 284 ? 86.385  59.763  104.041 1.00 25.01  ? 284  PHE B O     1 
ATOM   9312  C  CB    . PHE D 2 284 ? 83.360  59.848  102.815 1.00 19.19  ? 284  PHE B CB    1 
ATOM   9313  C  CG    . PHE D 2 284 ? 83.244  60.939  103.826 1.00 23.29  ? 284  PHE B CG    1 
ATOM   9314  C  CD1   . PHE D 2 284 ? 82.226  60.922  104.772 1.00 23.77  ? 284  PHE B CD1   1 
ATOM   9315  C  CD2   . PHE D 2 284 ? 84.178  61.966  103.875 1.00 23.57  ? 284  PHE B CD2   1 
ATOM   9316  C  CE1   . PHE D 2 284 ? 82.146  61.919  105.759 1.00 24.54  ? 284  PHE B CE1   1 
ATOM   9317  C  CE2   . PHE D 2 284 ? 84.102  62.961  104.861 1.00 26.53  ? 284  PHE B CE2   1 
ATOM   9318  C  CZ    . PHE D 2 284 ? 83.087  62.935  105.797 1.00 19.63  ? 284  PHE B CZ    1 
ATOM   9319  N  N     . THR D 2 285 ? 86.178  59.546  101.801 1.00 27.61  ? 285  THR B N     1 
ATOM   9320  C  CA    . THR D 2 285 ? 87.480  60.081  101.447 1.00 23.21  ? 285  THR B CA    1 
ATOM   9321  C  C     . THR D 2 285 ? 87.557  61.596  101.450 1.00 23.99  ? 285  THR B C     1 
ATOM   9322  O  O     . THR D 2 285 ? 86.539  62.305  101.448 1.00 19.57  ? 285  THR B O     1 
ATOM   9323  C  CB    . THR D 2 285 ? 87.865  59.638  100.021 1.00 26.20  ? 285  THR B CB    1 
ATOM   9324  O  OG1   . THR D 2 285 ? 87.037  60.326  99.085  1.00 30.06  ? 285  THR B OG1   1 
ATOM   9325  C  CG2   . THR D 2 285 ? 87.634  58.137  99.834  1.00 21.75  ? 285  THR B CG2   1 
ATOM   9326  N  N     . LEU D 2 286 ? 88.788  62.080  101.437 1.00 14.86  ? 286  LEU B N     1 
ATOM   9327  C  CA    . LEU D 2 286 ? 89.037  63.489  101.356 1.00 22.86  ? 286  LEU B CA    1 
ATOM   9328  C  C     . LEU D 2 286 ? 88.401  63.985  100.045 1.00 31.75  ? 286  LEU B C     1 
ATOM   9329  O  O     . LEU D 2 286 ? 87.777  65.058  100.036 1.00 31.26  ? 286  LEU B O     1 
ATOM   9330  C  CB    . LEU D 2 286 ? 90.540  63.774  101.367 1.00 22.55  ? 286  LEU B CB    1 
ATOM   9331  C  CG    . LEU D 2 286 ? 90.964  65.252  101.230 1.00 26.92  ? 286  LEU B CG    1 
ATOM   9332  C  CD1   . LEU D 2 286 ? 90.231  66.118  102.223 1.00 16.31  ? 286  LEU B CD1   1 
ATOM   9333  C  CD2   . LEU D 2 286 ? 92.513  65.327  101.437 1.00 22.45  ? 286  LEU B CD2   1 
ATOM   9334  N  N     . GLU D 2 287 ? 88.517  63.207  98.959  1.00 21.82  ? 287  GLU B N     1 
ATOM   9335  C  CA    . GLU D 2 287 ? 87.923  63.638  97.687  1.00 28.26  ? 287  GLU B CA    1 
ATOM   9336  C  C     . GLU D 2 287 ? 86.415  63.740  97.800  1.00 32.47  ? 287  GLU B C     1 
ATOM   9337  O  O     . GLU D 2 287 ? 85.821  64.707  97.320  1.00 30.66  ? 287  GLU B O     1 
ATOM   9338  C  CB    . GLU D 2 287 ? 88.242  62.691  96.517  1.00 21.64  ? 287  GLU B CB    1 
ATOM   9339  C  CG    . GLU D 2 287 ? 89.245  63.243  95.560  1.00 42.35  ? 287  GLU B CG    1 
ATOM   9340  C  CD    . GLU D 2 287 ? 88.771  64.527  94.882  1.00 53.95  ? 287  GLU B CD    1 
ATOM   9341  O  OE1   . GLU D 2 287 ? 89.542  65.513  94.857  1.00 52.29  ? 287  GLU B OE1   1 
ATOM   9342  O  OE2   . GLU D 2 287 ? 87.633  64.548  94.364  1.00 57.54  ? 287  GLU B OE2   1 
ATOM   9343  N  N     . GLU D 2 288 ? 85.786  62.753  98.427  1.00 20.26  ? 288  GLU B N     1 
ATOM   9344  C  CA    . GLU D 2 288 ? 84.340  62.819  98.557  1.00 32.19  ? 288  GLU B CA    1 
ATOM   9345  C  C     . GLU D 2 288 ? 83.909  64.042  99.394  1.00 33.90  ? 288  GLU B C     1 
ATOM   9346  O  O     . GLU D 2 288 ? 82.877  64.668  99.121  1.00 32.23  ? 288  GLU B O     1 
ATOM   9347  C  CB    . GLU D 2 288 ? 83.806  61.507  99.144  1.00 20.53  ? 288  GLU B CB    1 
ATOM   9348  C  CG    . GLU D 2 288 ? 84.067  60.307  98.249  1.00 32.15  ? 288  GLU B CG    1 
ATOM   9349  C  CD    . GLU D 2 288 ? 83.561  58.985  98.831  1.00 45.60  ? 288  GLU B CD    1 
ATOM   9350  O  OE1   . GLU D 2 288 ? 84.096  58.535  99.867  1.00 46.71  ? 288  GLU B OE1   1 
ATOM   9351  O  OE2   . GLU D 2 288 ? 82.620  58.399  98.253  1.00 54.00  ? 288  GLU B OE2   1 
ATOM   9352  N  N     . PHE D 2 289 ? 84.721  64.382  100.394 1.00 39.85  ? 289  PHE B N     1 
ATOM   9353  C  CA    . PHE D 2 289 ? 84.458  65.520  101.266 1.00 35.18  ? 289  PHE B CA    1 
ATOM   9354  C  C     . PHE D 2 289 ? 84.436  66.791  100.430 1.00 31.88  ? 289  PHE B C     1 
ATOM   9355  O  O     . PHE D 2 289 ? 83.465  67.546  100.468 1.00 27.55  ? 289  PHE B O     1 
ATOM   9356  C  CB    . PHE D 2 289 ? 85.544  65.619  102.366 1.00 34.97  ? 289  PHE B CB    1 
ATOM   9357  C  CG    . PHE D 2 289 ? 85.427  66.845  103.249 1.00 30.88  ? 289  PHE B CG    1 
ATOM   9358  C  CD1   . PHE D 2 289 ? 84.296  67.065  104.028 1.00 34.21  ? 289  PHE B CD1   1 
ATOM   9359  C  CD2   . PHE D 2 289 ? 86.472  67.746  103.341 1.00 33.49  ? 289  PHE B CD2   1 
ATOM   9360  C  CE1   . PHE D 2 289 ? 84.222  68.156  104.888 1.00 30.83  ? 289  PHE B CE1   1 
ATOM   9361  C  CE2   . PHE D 2 289 ? 86.401  68.834  104.196 1.00 34.46  ? 289  PHE B CE2   1 
ATOM   9362  C  CZ    . PHE D 2 289 ? 85.282  69.033  104.966 1.00 32.22  ? 289  PHE B CZ    1 
ATOM   9363  N  N     . ILE D 2 290 ? 85.486  67.033  99.653  1.00 31.92  ? 290  ILE B N     1 
ATOM   9364  C  CA    . ILE D 2 290 ? 85.461  68.240  98.858  1.00 36.96  ? 290  ILE B CA    1 
ATOM   9365  C  C     . ILE D 2 290 ? 84.338  68.266  97.824  1.00 37.00  ? 290  ILE B C     1 
ATOM   9366  O  O     . ILE D 2 290 ? 83.771  69.317  97.540  1.00 34.56  ? 290  ILE B O     1 
ATOM   9367  C  CB    . ILE D 2 290 ? 86.825  68.546  98.192  1.00 35.92  ? 290  ILE B CB    1 
ATOM   9368  C  CG1   . ILE D 2 290 ? 87.458  67.330  97.568  1.00 52.69  ? 290  ILE B CG1   1 
ATOM   9369  C  CG2   . ILE D 2 290 ? 87.791  68.987  99.242  1.00 52.82  ? 290  ILE B CG2   1 
ATOM   9370  C  CD1   . ILE D 2 290 ? 88.978  67.550  97.330  1.00 46.06  ? 290  ILE B CD1   1 
ATOM   9371  N  N     . GLN D 2 291 ? 83.973  67.122  97.279  1.00 28.75  ? 291  GLN B N     1 
ATOM   9372  C  CA    . GLN D 2 291 ? 82.921  67.149  96.290  1.00 41.90  ? 291  GLN B CA    1 
ATOM   9373  C  C     . GLN D 2 291 ? 81.579  67.419  96.936  1.00 41.32  ? 291  GLN B C     1 
ATOM   9374  O  O     . GLN D 2 291 ? 80.709  68.025  96.323  1.00 37.20  ? 291  GLN B O     1 
ATOM   9375  C  CB    . GLN D 2 291 ? 82.874  65.836  95.510  1.00 45.47  ? 291  GLN B CB    1 
ATOM   9376  C  CG    . GLN D 2 291 ? 83.230  66.013  94.035  1.00 61.34  ? 291  GLN B CG    1 
ATOM   9377  C  CD    . GLN D 2 291 ? 84.199  64.960  93.546  1.00 65.20  ? 291  GLN B CD    1 
ATOM   9378  O  OE1   . GLN D 2 291 ? 83.997  63.760  93.771  1.00 67.23  ? 291  GLN B OE1   1 
ATOM   9379  N  NE2   . GLN D 2 291 ? 85.262  65.399  92.876  1.00 63.58  ? 291  GLN B NE2   1 
ATOM   9380  N  N     . ALA D 2 292 ? 81.411  66.983  98.176  1.00 30.76  ? 292  ALA B N     1 
ATOM   9381  C  CA    . ALA D 2 292 ? 80.141  67.196  98.834  1.00 29.87  ? 292  ALA B CA    1 
ATOM   9382  C  C     . ALA D 2 292 ? 80.114  68.446  99.689  1.00 34.03  ? 292  ALA B C     1 
ATOM   9383  O  O     . ALA D 2 292 ? 79.065  68.794  100.230 1.00 40.61  ? 292  ALA B O     1 
ATOM   9384  C  CB    . ALA D 2 292 ? 79.800  65.993  99.699  1.00 16.79  ? 292  ALA B CB    1 
ATOM   9385  N  N     . PHE D 2 293 ? 81.241  69.139  99.814  1.00 31.71  ? 293  PHE B N     1 
ATOM   9386  C  CA    . PHE D 2 293 ? 81.248  70.297  100.699 1.00 37.30  ? 293  PHE B CA    1 
ATOM   9387  C  C     . PHE D 2 293 ? 80.292  71.445  100.347 1.00 35.65  ? 293  PHE B C     1 
ATOM   9388  O  O     . PHE D 2 293 ? 80.178  71.821  99.188  1.00 32.09  ? 293  PHE B O     1 
ATOM   9389  C  CB    . PHE D 2 293 ? 82.653  70.875  100.846 1.00 35.07  ? 293  PHE B CB    1 
ATOM   9390  C  CG    . PHE D 2 293 ? 82.731  71.940  101.878 1.00 36.26  ? 293  PHE B CG    1 
ATOM   9391  C  CD1   . PHE D 2 293 ? 82.853  71.605  103.228 1.00 46.87  ? 293  PHE B CD1   1 
ATOM   9392  C  CD2   . PHE D 2 293 ? 82.555  73.282  101.526 1.00 39.29  ? 293  PHE B CD2   1 
ATOM   9393  C  CE1   . PHE D 2 293 ? 82.790  72.592  104.231 1.00 44.04  ? 293  PHE B CE1   1 
ATOM   9394  C  CE2   . PHE D 2 293 ? 82.490  74.282  102.512 1.00 44.32  ? 293  PHE B CE2   1 
ATOM   9395  C  CZ    . PHE D 2 293 ? 82.607  73.934  103.870 1.00 48.67  ? 293  PHE B CZ    1 
ATOM   9396  N  N     . THR D 2 294 ? 79.606  71.971  101.366 1.00 26.12  ? 294  THR B N     1 
ATOM   9397  C  CA    . THR D 2 294 ? 78.700  73.108  101.215 1.00 32.70  ? 294  THR B CA    1 
ATOM   9398  C  C     . THR D 2 294 ? 78.541  73.740  102.577 1.00 33.86  ? 294  THR B C     1 
ATOM   9399  O  O     . THR D 2 294 ? 78.445  73.036  103.578 1.00 34.73  ? 294  THR B O     1 
ATOM   9400  C  CB    . THR D 2 294 ? 77.266  72.721  100.695 1.00 26.06  ? 294  THR B CB    1 
ATOM   9401  O  OG1   . THR D 2 294 ? 76.486  73.904  100.553 1.00 34.97  ? 294  THR B OG1   1 
ATOM   9402  C  CG2   . THR D 2 294 ? 76.543  71.871  101.661 1.00 23.64  ? 294  THR B CG2   1 
ATOM   9403  N  N     . TRP D 2 295 ? 78.500  75.068  102.618 1.00 37.90  ? 295  TRP B N     1 
ATOM   9404  C  CA    . TRP D 2 295 ? 78.338  75.768  103.878 1.00 29.23  ? 295  TRP B CA    1 
ATOM   9405  C  C     . TRP D 2 295 ? 76.940  75.526  104.468 1.00 34.44  ? 295  TRP B C     1 
ATOM   9406  O  O     . TRP D 2 295 ? 76.686  75.829  105.626 1.00 30.43  ? 295  TRP B O     1 
ATOM   9407  C  CB    . TRP D 2 295 ? 78.622  77.260  103.688 1.00 26.98  ? 295  TRP B CB    1 
ATOM   9408  C  CG    . TRP D 2 295 ? 80.081  77.540  103.389 1.00 32.85  ? 295  TRP B CG    1 
ATOM   9409  C  CD1   . TRP D 2 295 ? 80.614  77.974  102.200 1.00 25.44  ? 295  TRP B CD1   1 
ATOM   9410  C  CD2   . TRP D 2 295 ? 81.191  77.350  104.280 1.00 23.81  ? 295  TRP B CD2   1 
ATOM   9411  N  NE1   . TRP D 2 295 ? 81.985  78.064  102.301 1.00 32.20  ? 295  TRP B NE1   1 
ATOM   9412  C  CE2   . TRP D 2 295 ? 82.365  77.685  103.565 1.00 29.60  ? 295  TRP B CE2   1 
ATOM   9413  C  CE3   . TRP D 2 295 ? 81.306  76.934  105.609 1.00 32.45  ? 295  TRP B CE3   1 
ATOM   9414  C  CZ2   . TRP D 2 295 ? 83.644  77.608  104.138 1.00 26.92  ? 295  TRP B CZ2   1 
ATOM   9415  C  CZ3   . TRP D 2 295 ? 82.589  76.861  106.188 1.00 37.54  ? 295  TRP B CZ3   1 
ATOM   9416  C  CH2   . TRP D 2 295 ? 83.738  77.198  105.447 1.00 24.34  ? 295  TRP B CH2   1 
ATOM   9417  N  N     . GLU D 2 296 ? 76.037  74.958  103.677 1.00 35.17  ? 296  GLU B N     1 
ATOM   9418  C  CA    . GLU D 2 296 ? 74.697  74.657  104.187 1.00 46.95  ? 296  GLU B CA    1 
ATOM   9419  C  C     . GLU D 2 296 ? 74.744  73.486  105.161 1.00 44.04  ? 296  GLU B C     1 
ATOM   9420  O  O     . GLU D 2 296 ? 73.874  73.367  106.007 1.00 40.62  ? 296  GLU B O     1 
ATOM   9421  C  CB    . GLU D 2 296 ? 73.730  74.279  103.060 1.00 45.30  ? 296  GLU B CB    1 
ATOM   9422  C  CG    . GLU D 2 296 ? 73.167  75.434  102.290 1.00 65.27  ? 296  GLU B CG    1 
ATOM   9423  C  CD    . GLU D 2 296 ? 72.731  75.009  100.907 1.00 79.28  ? 296  GLU B CD    1 
ATOM   9424  O  OE1   . GLU D 2 296 ? 73.634  74.639  100.120 1.00 78.87  ? 296  GLU B OE1   1 
ATOM   9425  O  OE2   . GLU D 2 296 ? 71.503  75.033  100.612 1.00 78.59  ? 296  GLU B OE2   1 
ATOM   9426  N  N     . ARG D 2 297 ? 75.744  72.615  105.028 1.00 44.41  ? 297  ARG B N     1 
ATOM   9427  C  CA    . ARG D 2 297 ? 75.854  71.451  105.916 1.00 40.50  ? 297  ARG B CA    1 
ATOM   9428  C  C     . ARG D 2 297 ? 76.772  71.717  107.113 1.00 36.99  ? 297  ARG B C     1 
ATOM   9429  O  O     . ARG D 2 297 ? 77.077  70.805  107.869 1.00 37.21  ? 297  ARG B O     1 
ATOM   9430  C  CB    . ARG D 2 297 ? 76.405  70.233  105.169 1.00 35.51  ? 297  ARG B CB    1 
ATOM   9431  C  CG    . ARG D 2 297 ? 75.765  69.871  103.796 1.00 51.45  ? 297  ARG B CG    1 
ATOM   9432  C  CD    . ARG D 2 297 ? 74.455  69.111  103.872 1.00 41.21  ? 297  ARG B CD    1 
ATOM   9433  N  NE    . ARG D 2 297 ? 74.490  68.045  104.866 1.00 50.18  ? 297  ARG B NE    1 
ATOM   9434  C  CZ    . ARG D 2 297 ? 73.409  67.414  105.309 1.00 49.26  ? 297  ARG B CZ    1 
ATOM   9435  N  NH1   . ARG D 2 297 ? 72.221  67.750  104.828 1.00 51.55  ? 297  ARG B NH1   1 
ATOM   9436  N  NH2   . ARG D 2 297 ? 73.507  66.471  106.248 1.00 43.41  ? 297  ARG B NH2   1 
ATOM   9437  N  N     . VAL D 2 298 ? 77.238  72.943  107.282 1.00 29.21  ? 298  VAL B N     1 
ATOM   9438  C  CA    . VAL D 2 298 ? 78.107  73.236  108.418 1.00 34.68  ? 298  VAL B CA    1 
ATOM   9439  C  C     . VAL D 2 298 ? 77.288  73.609  109.634 1.00 33.09  ? 298  VAL B C     1 
ATOM   9440  O  O     . VAL D 2 298 ? 76.450  74.491  109.540 1.00 44.99  ? 298  VAL B O     1 
ATOM   9441  C  CB    . VAL D 2 298 ? 79.039  74.422  108.122 1.00 36.11  ? 298  VAL B CB    1 
ATOM   9442  C  CG1   . VAL D 2 298 ? 79.794  74.823  109.392 1.00 22.70  ? 298  VAL B CG1   1 
ATOM   9443  C  CG2   . VAL D 2 298 ? 79.986  74.054  107.008 1.00 34.14  ? 298  VAL B CG2   1 
ATOM   9444  N  N     . SER D 2 299 ? 77.518  72.968  110.776 1.00 34.25  ? 299  SER B N     1 
ATOM   9445  C  CA    . SER D 2 299 ? 76.746  73.309  111.987 1.00 37.80  ? 299  SER B CA    1 
ATOM   9446  C  C     . SER D 2 299 ? 77.646  74.131  112.901 1.00 35.69  ? 299  SER B C     1 
ATOM   9447  O  O     . SER D 2 299 ? 78.861  73.895  112.961 1.00 35.32  ? 299  SER B O     1 
ATOM   9448  C  CB    . SER D 2 299 ? 76.243  72.050  112.718 1.00 32.75  ? 299  SER B CB    1 
ATOM   9449  O  OG    . SER D 2 299 ? 77.324  71.248  113.160 1.00 41.68  ? 299  SER B OG    1 
ATOM   9450  N  N     . LEU D 2 300 ? 77.051  75.069  113.637 1.00 33.41  ? 300  LEU B N     1 
ATOM   9451  C  CA    . LEU D 2 300 ? 77.833  75.959  114.476 1.00 27.82  ? 300  LEU B CA    1 
ATOM   9452  C  C     . LEU D 2 300 ? 78.037  75.665  115.950 1.00 31.52  ? 300  LEU B C     1 
ATOM   9453  O  O     . LEU D 2 300 ? 78.634  76.482  116.661 1.00 35.18  ? 300  LEU B O     1 
ATOM   9454  C  CB    . LEU D 2 300 ? 77.312  77.380  114.303 1.00 36.32  ? 300  LEU B CB    1 
ATOM   9455  C  CG    . LEU D 2 300 ? 77.383  77.936  112.875 1.00 42.43  ? 300  LEU B CG    1 
ATOM   9456  C  CD1   . LEU D 2 300 ? 76.613  79.274  112.799 1.00 42.21  ? 300  LEU B CD1   1 
ATOM   9457  C  CD2   . LEU D 2 300 ? 78.829  78.119  112.456 1.00 37.82  ? 300  LEU B CD2   1 
ATOM   9458  N  N     . GLY D 2 301 ? 77.566  74.525  116.436 1.00 23.66  ? 301  GLY B N     1 
ATOM   9459  C  CA    . GLY D 2 301 ? 77.816  74.221  117.837 1.00 27.35  ? 301  GLY B CA    1 
ATOM   9460  C  C     . GLY D 2 301 ? 79.279  73.818  118.027 1.00 30.23  ? 301  GLY B C     1 
ATOM   9461  O  O     . GLY D 2 301 ? 79.840  73.137  117.172 1.00 48.99  ? 301  GLY B O     1 
ATOM   9462  N  N     . GLY D 2 302 ? 79.920  74.249  119.105 1.00 32.02  ? 302  GLY B N     1 
ATOM   9463  C  CA    . GLY D 2 302 ? 81.314  73.879  119.338 1.00 31.88  ? 302  GLY B CA    1 
ATOM   9464  C  C     . GLY D 2 302 ? 81.398  72.386  119.636 1.00 38.67  ? 302  GLY B C     1 
ATOM   9465  O  O     . GLY D 2 302 ? 80.911  71.928  120.666 1.00 39.91  ? 302  GLY B O     1 
ATOM   9466  N  N     . PRO D 2 303 ? 82.035  71.595  118.769 1.00 34.46  ? 303  PRO B N     1 
ATOM   9467  C  CA    . PRO D 2 303 ? 82.100  70.157  119.038 1.00 34.22  ? 303  PRO B CA    1 
ATOM   9468  C  C     . PRO D 2 303 ? 83.166  69.642  120.013 1.00 36.42  ? 303  PRO B C     1 
ATOM   9469  O  O     . PRO D 2 303 ? 84.310  70.111  120.041 1.00 30.26  ? 303  PRO B O     1 
ATOM   9470  C  CB    . PRO D 2 303 ? 82.266  69.576  117.639 1.00 34.53  ? 303  PRO B CB    1 
ATOM   9471  C  CG    . PRO D 2 303 ? 83.259  70.583  117.025 1.00 33.68  ? 303  PRO B CG    1 
ATOM   9472  C  CD    . PRO D 2 303 ? 82.689  71.937  117.489 1.00 35.72  ? 303  PRO B CD    1 
ATOM   9473  N  N     . VAL D 2 304 ? 82.774  68.668  120.820 1.00 36.90  ? 304  VAL B N     1 
ATOM   9474  C  CA    . VAL D 2 304 ? 83.709  68.052  121.758 1.00 40.06  ? 304  VAL B CA    1 
ATOM   9475  C  C     . VAL D 2 304 ? 84.462  67.008  120.939 1.00 35.01  ? 304  VAL B C     1 
ATOM   9476  O  O     . VAL D 2 304 ? 83.855  66.189  120.278 1.00 33.26  ? 304  VAL B O     1 
ATOM   9477  C  CB    . VAL D 2 304 ? 82.976  67.337  122.938 1.00 37.31  ? 304  VAL B CB    1 
ATOM   9478  C  CG1   . VAL D 2 304 ? 83.848  66.214  123.508 1.00 27.97  ? 304  VAL B CG1   1 
ATOM   9479  C  CG2   . VAL D 2 304 ? 82.660  68.328  124.017 1.00 34.41  ? 304  VAL B CG2   1 
ATOM   9480  N  N     . PHE D 2 305 ? 85.781  67.076  120.953 1.00 38.22  ? 305  PHE B N     1 
ATOM   9481  C  CA    . PHE D 2 305 ? 86.586  66.113  120.228 1.00 33.41  ? 305  PHE B CA    1 
ATOM   9482  C  C     . PHE D 2 305 ? 86.524  64.900  121.133 1.00 38.42  ? 305  PHE B C     1 
ATOM   9483  O  O     . PHE D 2 305 ? 86.978  64.956  122.282 1.00 36.33  ? 305  PHE B O     1 
ATOM   9484  C  CB    . PHE D 2 305 ? 88.018  66.627  120.104 1.00 30.83  ? 305  PHE B CB    1 
ATOM   9485  C  CG    . PHE D 2 305 ? 88.923  65.726  119.322 1.00 36.41  ? 305  PHE B CG    1 
ATOM   9486  C  CD1   . PHE D 2 305 ? 89.438  64.567  119.896 1.00 28.83  ? 305  PHE B CD1   1 
ATOM   9487  C  CD2   . PHE D 2 305 ? 89.273  66.045  118.015 1.00 33.83  ? 305  PHE B CD2   1 
ATOM   9488  C  CE1   . PHE D 2 305 ? 90.281  63.749  119.188 1.00 38.88  ? 305  PHE B CE1   1 
ATOM   9489  C  CE2   . PHE D 2 305 ? 90.116  65.238  117.291 1.00 29.28  ? 305  PHE B CE2   1 
ATOM   9490  C  CZ    . PHE D 2 305 ? 90.627  64.080  117.877 1.00 46.55  ? 305  PHE B CZ    1 
ATOM   9491  N  N     . ASP D 2 306 ? 85.953  63.816  120.613 1.00 37.11  ? 306  ASP B N     1 
ATOM   9492  C  CA    . ASP D 2 306 ? 85.775  62.560  121.362 1.00 40.39  ? 306  ASP B CA    1 
ATOM   9493  C  C     . ASP D 2 306 ? 86.708  61.405  120.903 1.00 35.13  ? 306  ASP B C     1 
ATOM   9494  O  O     . ASP D 2 306 ? 86.495  60.791  119.852 1.00 28.43  ? 306  ASP B O     1 
ATOM   9495  C  CB    . ASP D 2 306 ? 84.291  62.169  121.256 1.00 33.78  ? 306  ASP B CB    1 
ATOM   9496  C  CG    . ASP D 2 306 ? 83.971  60.827  121.868 1.00 40.39  ? 306  ASP B CG    1 
ATOM   9497  O  OD1   . ASP D 2 306 ? 82.809  60.380  121.638 1.00 35.07  ? 306  ASP B OD1   1 
ATOM   9498  O  OD2   . ASP D 2 306 ? 84.850  60.235  122.556 1.00 31.77  ? 306  ASP B OD2   1 
ATOM   9499  N  N     . LEU D 2 307 ? 87.745  61.144  121.699 1.00 32.72  ? 307  LEU B N     1 
ATOM   9500  C  CA    . LEU D 2 307 ? 88.715  60.091  121.416 1.00 40.31  ? 307  LEU B CA    1 
ATOM   9501  C  C     . LEU D 2 307 ? 88.053  58.763  121.160 1.00 37.89  ? 307  LEU B C     1 
ATOM   9502  O  O     . LEU D 2 307 ? 88.587  57.930  120.427 1.00 33.44  ? 307  LEU B O     1 
ATOM   9503  C  CB    . LEU D 2 307 ? 89.684  59.907  122.581 1.00 35.47  ? 307  LEU B CB    1 
ATOM   9504  C  CG    . LEU D 2 307 ? 90.803  60.926  122.694 1.00 53.54  ? 307  LEU B CG    1 
ATOM   9505  C  CD1   . LEU D 2 307 ? 91.509  60.764  124.034 1.00 53.89  ? 307  LEU B CD1   1 
ATOM   9506  C  CD2   . LEU D 2 307 ? 91.762  60.739  121.530 1.00 46.73  ? 307  LEU B CD2   1 
ATOM   9507  N  N     . GLU D 2 308 ? 86.892  58.559  121.771 1.00 38.05  ? 308  GLU B N     1 
ATOM   9508  C  CA    . GLU D 2 308 ? 86.191  57.297  121.602 1.00 38.23  ? 308  GLU B CA    1 
ATOM   9509  C  C     . GLU D 2 308 ? 85.611  57.154  120.194 1.00 33.47  ? 308  GLU B C     1 
ATOM   9510  O  O     . GLU D 2 308 ? 85.711  56.083  119.594 1.00 32.04  ? 308  GLU B O     1 
ATOM   9511  C  CB    . GLU D 2 308 ? 85.110  57.150  122.684 1.00 46.68  ? 308  GLU B CB    1 
ATOM   9512  C  CG    . GLU D 2 308 ? 84.714  55.712  123.003 1.00 68.69  ? 308  GLU B CG    1 
ATOM   9513  C  CD    . GLU D 2 308 ? 85.908  54.823  123.374 1.00 79.65  ? 308  GLU B CD    1 
ATOM   9514  O  OE1   . GLU D 2 308 ? 86.780  55.293  124.142 1.00 78.04  ? 308  GLU B OE1   1 
ATOM   9515  O  OE2   . GLU D 2 308 ? 85.967  53.658  122.902 1.00 71.48  ? 308  GLU B OE2   1 
ATOM   9516  N  N     . LYS D 2 309 ? 85.010  58.204  119.640 1.00 29.13  ? 309  LYS B N     1 
ATOM   9517  C  CA    . LYS D 2 309 ? 84.493  58.045  118.273 1.00 29.03  ? 309  LYS B CA    1 
ATOM   9518  C  C     . LYS D 2 309 ? 85.699  57.992  117.284 1.00 29.94  ? 309  LYS B C     1 
ATOM   9519  O  O     . LYS D 2 309 ? 85.691  57.219  116.306 1.00 28.00  ? 309  LYS B O     1 
ATOM   9520  C  CB    . LYS D 2 309 ? 83.522  59.163  117.927 1.00 21.69  ? 309  LYS B CB    1 
ATOM   9521  C  CG    . LYS D 2 309 ? 82.253  58.691  117.222 1.00 25.48  ? 309  LYS B CG    1 
ATOM   9522  C  CD    . LYS D 2 309 ? 82.328  58.891  115.732 1.00 29.20  ? 309  LYS B CD    1 
ATOM   9523  C  CE    . LYS D 2 309 ? 81.027  58.590  115.035 1.00 38.71  ? 309  LYS B CE    1 
ATOM   9524  N  NZ    . LYS D 2 309 ? 79.974  59.599  115.372 1.00 49.68  ? 309  LYS B NZ    1 
ATOM   9525  N  N     . LEU D 2 310 ? 86.749  58.767  117.560 1.00 25.01  ? 310  LEU B N     1 
ATOM   9526  C  CA    . LEU D 2 310 ? 87.940  58.758  116.707 1.00 24.78  ? 310  LEU B CA    1 
ATOM   9527  C  C     . LEU D 2 310 ? 88.457  57.316  116.679 1.00 29.55  ? 310  LEU B C     1 
ATOM   9528  O  O     . LEU D 2 310 ? 88.725  56.772  115.605 1.00 26.59  ? 310  LEU B O     1 
ATOM   9529  C  CB    . LEU D 2 310 ? 89.042  59.648  117.265 1.00 26.67  ? 310  LEU B CB    1 
ATOM   9530  C  CG    . LEU D 2 310 ? 90.073  60.180  116.276 1.00 35.76  ? 310  LEU B CG    1 
ATOM   9531  C  CD1   . LEU D 2 310 ? 91.394  60.345  116.986 1.00 22.48  ? 310  LEU B CD1   1 
ATOM   9532  C  CD2   . LEU D 2 310 ? 90.206  59.263  115.085 1.00 30.56  ? 310  LEU B CD2   1 
ATOM   9533  N  N     . ARG D 2 311 ? 88.597  56.705  117.860 1.00 26.31  ? 311  ARG B N     1 
ATOM   9534  C  CA    . ARG D 2 311 ? 89.051  55.308  117.950 1.00 35.54  ? 311  ARG B CA    1 
ATOM   9535  C  C     . ARG D 2 311 ? 88.149  54.379  117.140 1.00 33.16  ? 311  ARG B C     1 
ATOM   9536  O  O     . ARG D 2 311 ? 88.639  53.516  116.407 1.00 33.76  ? 311  ARG B O     1 
ATOM   9537  C  CB    . ARG D 2 311 ? 89.077  54.816  119.401 1.00 32.48  ? 311  ARG B CB    1 
ATOM   9538  C  CG    . ARG D 2 311 ? 90.250  55.322  120.200 1.00 44.35  ? 311  ARG B CG    1 
ATOM   9539  C  CD    . ARG D 2 311 ? 90.205  54.842  121.654 1.00 51.93  ? 311  ARG B CD    1 
ATOM   9540  N  NE    . ARG D 2 311 ? 90.847  53.547  121.836 1.00 57.87  ? 311  ARG B NE    1 
ATOM   9541  C  CZ    . ARG D 2 311 ? 90.264  52.372  121.619 1.00 67.54  ? 311  ARG B CZ    1 
ATOM   9542  N  NH1   . ARG D 2 311 ? 88.999  52.295  121.209 1.00 69.41  ? 311  ARG B NH1   1 
ATOM   9543  N  NH2   . ARG D 2 311 ? 90.961  51.262  121.800 1.00 70.05  ? 311  ARG B NH2   1 
ATOM   9544  N  N     . TRP D 2 312 ? 86.838  54.542  117.276 1.00 28.00  ? 312  TRP B N     1 
ATOM   9545  C  CA    . TRP D 2 312 ? 85.923  53.709  116.518 1.00 29.52  ? 312  TRP B CA    1 
ATOM   9546  C  C     . TRP D 2 312 ? 86.209  53.877  115.029 1.00 31.84  ? 312  TRP B C     1 
ATOM   9547  O  O     . TRP D 2 312 ? 86.308  52.897  114.278 1.00 24.78  ? 312  TRP B O     1 
ATOM   9548  C  CB    . TRP D 2 312 ? 84.476  54.118  116.775 1.00 27.38  ? 312  TRP B CB    1 
ATOM   9549  C  CG    . TRP D 2 312 ? 83.569  53.518  115.785 1.00 26.05  ? 312  TRP B CG    1 
ATOM   9550  C  CD1   . TRP D 2 312 ? 83.106  52.216  115.756 1.00 28.88  ? 312  TRP B CD1   1 
ATOM   9551  C  CD2   . TRP D 2 312 ? 82.996  54.174  114.659 1.00 20.39  ? 312  TRP B CD2   1 
ATOM   9552  N  NE1   . TRP D 2 312 ? 82.266  52.038  114.674 1.00 26.01  ? 312  TRP B NE1   1 
ATOM   9553  C  CE2   . TRP D 2 312 ? 82.179  53.226  113.987 1.00 33.03  ? 312  TRP B CE2   1 
ATOM   9554  C  CE3   . TRP D 2 312 ? 83.086  55.467  114.148 1.00 25.94  ? 312  TRP B CE3   1 
ATOM   9555  C  CZ2   . TRP D 2 312 ? 81.457  53.550  112.834 1.00 25.17  ? 312  TRP B CZ2   1 
ATOM   9556  C  CZ3   . TRP D 2 312 ? 82.370  55.783  112.993 1.00 25.77  ? 312  TRP B CZ3   1 
ATOM   9557  C  CH2   . TRP D 2 312 ? 81.570  54.829  112.357 1.00 19.37  ? 312  TRP B CH2   1 
ATOM   9558  N  N     . MET D 2 313 ? 86.327  55.133  114.619 1.00 23.30  ? 313  MET B N     1 
ATOM   9559  C  CA    . MET D 2 313 ? 86.571  55.437  113.234 1.00 27.39  ? 313  MET B CA    1 
ATOM   9560  C  C     . MET D 2 313 ? 87.884  54.817  112.755 1.00 21.13  ? 313  MET B C     1 
ATOM   9561  O  O     . MET D 2 313 ? 87.952  54.265  111.658 1.00 23.70  ? 313  MET B O     1 
ATOM   9562  C  CB    . MET D 2 313 ? 86.601  56.956  113.035 1.00 23.31  ? 313  MET B CB    1 
ATOM   9563  C  CG    . MET D 2 313 ? 86.771  57.327  111.556 1.00 44.10  ? 313  MET B CG    1 
ATOM   9564  S  SD    . MET D 2 313 ? 85.966  58.856  111.029 1.00 44.39  ? 313  MET B SD    1 
ATOM   9565  C  CE    . MET D 2 313 ? 84.296  58.452  111.390 1.00 38.16  ? 313  MET B CE    1 
ATOM   9566  N  N     . ASN D 2 314 ? 88.914  54.907  113.594 1.00 20.36  ? 314  ASN B N     1 
ATOM   9567  C  CA    . ASN D 2 314 ? 90.227  54.403  113.255 1.00 20.95  ? 314  ASN B CA    1 
ATOM   9568  C  C     . ASN D 2 314 ? 90.114  52.910  113.020 1.00 22.76  ? 314  ASN B C     1 
ATOM   9569  O  O     . ASN D 2 314 ? 90.694  52.392  112.089 1.00 24.38  ? 314  ASN B O     1 
ATOM   9570  C  CB    . ASN D 2 314 ? 91.211  54.728  114.368 1.00 16.38  ? 314  ASN B CB    1 
ATOM   9571  C  CG    . ASN D 2 314 ? 92.650  54.719  113.888 1.00 31.24  ? 314  ASN B CG    1 
ATOM   9572  O  OD1   . ASN D 2 314 ? 93.094  55.623  113.138 1.00 20.85  ? 314  ASN B OD1   1 
ATOM   9573  N  ND2   . ASN D 2 314 ? 93.407  53.693  114.318 1.00 21.92  ? 314  ASN B ND2   1 
ATOM   9574  N  N     . GLY D 2 315 ? 89.326  52.240  113.856 1.00 31.45  ? 315  GLY B N     1 
ATOM   9575  C  CA    . GLY D 2 315 ? 89.096  50.809  113.720 1.00 30.85  ? 315  GLY B CA    1 
ATOM   9576  C  C     . GLY D 2 315 ? 88.328  50.525  112.437 1.00 37.09  ? 315  GLY B C     1 
ATOM   9577  O  O     . GLY D 2 315 ? 88.593  49.544  111.728 1.00 41.05  ? 315  GLY B O     1 
ATOM   9578  N  N     . LYS D 2 316 ? 87.384  51.398  112.119 1.00 28.77  ? 316  LYS B N     1 
ATOM   9579  C  CA    . LYS D 2 316 ? 86.605  51.234  110.899 1.00 32.29  ? 316  LYS B CA    1 
ATOM   9580  C  C     . LYS D 2 316 ? 87.526  51.285  109.667 1.00 22.67  ? 316  LYS B C     1 
ATOM   9581  O  O     . LYS D 2 316 ? 87.359  50.515  108.728 1.00 32.27  ? 316  LYS B O     1 
ATOM   9582  C  CB    . LYS D 2 316 ? 85.545  52.342  110.801 1.00 28.51  ? 316  LYS B CB    1 
ATOM   9583  C  CG    . LYS D 2 316 ? 84.326  51.978  109.970 1.00 39.81  ? 316  LYS B CG    1 
ATOM   9584  C  CD    . LYS D 2 316 ? 83.232  51.417  110.863 1.00 38.64  ? 316  LYS B CD    1 
ATOM   9585  C  CE    . LYS D 2 316 ? 81.845  51.657  110.256 1.00 39.07  ? 316  LYS B CE    1 
ATOM   9586  N  NZ    . LYS D 2 316 ? 81.351  50.538  109.410 1.00 35.91  ? 316  LYS B NZ    1 
ATOM   9587  N  N     . TYR D 2 317 ? 88.494  52.195  109.668 1.00 26.56  ? 317  TYR B N     1 
ATOM   9588  C  CA    . TYR D 2 317 ? 89.414  52.307  108.542 1.00 26.23  ? 317  TYR B CA    1 
ATOM   9589  C  C     . TYR D 2 317 ? 90.254  51.052  108.406 1.00 24.88  ? 317  TYR B C     1 
ATOM   9590  O  O     . TYR D 2 317 ? 90.393  50.477  107.335 1.00 35.27  ? 317  TYR B O     1 
ATOM   9591  C  CB    . TYR D 2 317 ? 90.316  53.528  108.734 1.00 27.37  ? 317  TYR B CB    1 
ATOM   9592  C  CG    . TYR D 2 317 ? 89.763  54.769  108.061 1.00 29.37  ? 317  TYR B CG    1 
ATOM   9593  C  CD1   . TYR D 2 317 ? 90.321  55.240  106.876 1.00 22.65  ? 317  TYR B CD1   1 
ATOM   9594  C  CD2   . TYR D 2 317 ? 88.603  55.383  108.534 1.00 22.26  ? 317  TYR B CD2   1 
ATOM   9595  C  CE1   . TYR D 2 317 ? 89.738  56.270  106.166 1.00 29.62  ? 317  TYR B CE1   1 
ATOM   9596  C  CE2   . TYR D 2 317 ? 88.008  56.429  107.827 1.00 25.99  ? 317  TYR B CE2   1 
ATOM   9597  C  CZ    . TYR D 2 317 ? 88.585  56.854  106.637 1.00 26.28  ? 317  TYR B CZ    1 
ATOM   9598  O  OH    . TYR D 2 317 ? 87.969  57.792  105.866 1.00 25.17  ? 317  TYR B OH    1 
ATOM   9599  N  N     . ILE D 2 318 ? 90.816  50.627  109.519 1.00 29.22  ? 318  ILE B N     1 
ATOM   9600  C  CA    . ILE D 2 318 ? 91.644  49.452  109.544 1.00 22.86  ? 318  ILE B CA    1 
ATOM   9601  C  C     . ILE D 2 318 ? 90.889  48.240  109.032 1.00 28.39  ? 318  ILE B C     1 
ATOM   9602  O  O     . ILE D 2 318 ? 91.466  47.407  108.353 1.00 21.59  ? 318  ILE B O     1 
ATOM   9603  C  CB    . ILE D 2 318 ? 92.115  49.166  110.969 1.00 23.83  ? 318  ILE B CB    1 
ATOM   9604  C  CG1   . ILE D 2 318 ? 93.185  50.200  111.361 1.00 20.28  ? 318  ILE B CG1   1 
ATOM   9605  C  CG2   . ILE D 2 318 ? 92.544  47.694  111.081 1.00 20.74  ? 318  ILE B CG2   1 
ATOM   9606  C  CD1   . ILE D 2 318 ? 93.509  50.291  112.834 1.00 18.25  ? 318  ILE B CD1   1 
ATOM   9607  N  N     . ARG D 2 319 ? 89.593  48.139  109.313 1.00 23.43  ? 319  ARG B N     1 
ATOM   9608  C  CA    . ARG D 2 319 ? 88.920  46.925  108.886 1.00 28.44  ? 319  ARG B CA    1 
ATOM   9609  C  C     . ARG D 2 319 ? 88.140  47.018  107.573 1.00 30.22  ? 319  ARG B C     1 
ATOM   9610  O  O     . ARG D 2 319 ? 87.912  46.011  106.899 1.00 33.88  ? 319  ARG B O     1 
ATOM   9611  C  CB    . ARG D 2 319 ? 88.054  46.369  110.060 1.00 17.97  ? 319  ARG B CB    1 
ATOM   9612  C  CG    . ARG D 2 319 ? 86.599  46.842  110.136 1.00 47.48  ? 319  ARG B CG    1 
ATOM   9613  C  CD    . ARG D 2 319 ? 85.879  46.244  111.367 1.00 45.37  ? 319  ARG B CD    1 
ATOM   9614  N  NE    . ARG D 2 319 ? 86.570  46.650  112.575 1.00 36.35  ? 319  ARG B NE    1 
ATOM   9615  C  CZ    . ARG D 2 319 ? 86.194  47.668  113.350 1.00 39.20  ? 319  ARG B CZ    1 
ATOM   9616  N  NH1   . ARG D 2 319 ? 86.915  47.997  114.435 1.00 23.64  ? 319  ARG B NH1   1 
ATOM   9617  N  NH2   . ARG D 2 319 ? 85.078  48.333  113.069 1.00 26.78  ? 319  ARG B NH2   1 
ATOM   9618  N  N     . GLU D 2 320 ? 87.804  48.227  107.160 1.00 25.58  ? 320  GLU B N     1 
ATOM   9619  C  CA    . GLU D 2 320 ? 87.008  48.369  105.976 1.00 21.55  ? 320  GLU B CA    1 
ATOM   9620  C  C     . GLU D 2 320 ? 87.515  49.266  104.890 1.00 21.12  ? 320  GLU B C     1 
ATOM   9621  O  O     . GLU D 2 320 ? 86.977  49.226  103.802 1.00 28.83  ? 320  GLU B O     1 
ATOM   9622  C  CB    . GLU D 2 320 ? 85.612  48.856  106.372 1.00 30.57  ? 320  GLU B CB    1 
ATOM   9623  C  CG    . GLU D 2 320 ? 84.854  47.945  107.302 1.00 29.93  ? 320  GLU B CG    1 
ATOM   9624  C  CD    . GLU D 2 320 ? 83.546  48.571  107.743 1.00 42.11  ? 320  GLU B CD    1 
ATOM   9625  O  OE1   . GLU D 2 320 ? 83.017  48.216  108.824 1.00 54.16  ? 320  GLU B OE1   1 
ATOM   9626  O  OE2   . GLU D 2 320 ? 83.040  49.424  106.993 1.00 55.53  ? 320  GLU B OE2   1 
ATOM   9627  N  N     . VAL D 2 321 ? 88.529  50.079  105.143 1.00 23.20  ? 321  VAL B N     1 
ATOM   9628  C  CA    . VAL D 2 321 ? 88.973  50.970  104.084 1.00 22.38  ? 321  VAL B CA    1 
ATOM   9629  C  C     . VAL D 2 321 ? 90.304  50.617  103.507 1.00 22.25  ? 321  VAL B C     1 
ATOM   9630  O  O     . VAL D 2 321 ? 90.475  50.608  102.298 1.00 29.32  ? 321  VAL B O     1 
ATOM   9631  C  CB    . VAL D 2 321 ? 89.038  52.424  104.534 1.00 23.96  ? 321  VAL B CB    1 
ATOM   9632  C  CG1   . VAL D 2 321 ? 89.362  53.324  103.332 1.00 28.61  ? 321  VAL B CG1   1 
ATOM   9633  C  CG2   . VAL D 2 321 ? 87.726  52.843  105.120 1.00 28.08  ? 321  VAL B CG2   1 
ATOM   9634  N  N     . LEU D 2 322 ? 91.264  50.362  104.375 1.00 32.54  ? 322  LEU B N     1 
ATOM   9635  C  CA    . LEU D 2 322 ? 92.588  49.980  103.937 1.00 22.23  ? 322  LEU B CA    1 
ATOM   9636  C  C     . LEU D 2 322 ? 92.559  48.521  103.546 1.00 27.51  ? 322  LEU B C     1 
ATOM   9637  O  O     . LEU D 2 322 ? 91.709  47.749  104.006 1.00 26.11  ? 322  LEU B O     1 
ATOM   9638  C  CB    . LEU D 2 322 ? 93.588  50.103  105.059 1.00 26.71  ? 322  LEU B CB    1 
ATOM   9639  C  CG    . LEU D 2 322 ? 93.729  51.385  105.882 1.00 44.58  ? 322  LEU B CG    1 
ATOM   9640  C  CD1   . LEU D 2 322 ? 95.191  51.455  106.339 1.00 28.12  ? 322  LEU B CD1   1 
ATOM   9641  C  CD2   . LEU D 2 322 ? 93.343  52.627  105.090 1.00 22.39  ? 322  LEU B CD2   1 
ATOM   9642  N  N     . SER D 2 323 ? 93.502  48.137  102.695 1.00 26.31  ? 323  SER B N     1 
ATOM   9643  C  CA    . SER D 2 323 ? 93.617  46.742  102.309 1.00 31.66  ? 323  SER B CA    1 
ATOM   9644  C  C     . SER D 2 323 ? 94.430  46.033  103.438 1.00 33.12  ? 323  SER B C     1 
ATOM   9645  O  O     . SER D 2 323 ? 95.087  46.685  104.281 1.00 25.44  ? 323  SER B O     1 
ATOM   9646  C  CB    . SER D 2 323 ? 94.373  46.627  100.988 1.00 28.53  ? 323  SER B CB    1 
ATOM   9647  O  OG    . SER D 2 323 ? 95.748  46.961  101.180 1.00 35.94  ? 323  SER B OG    1 
ATOM   9648  N  N     . LEU D 2 324 ? 94.379  44.706  103.440 1.00 26.88  ? 324  LEU B N     1 
ATOM   9649  C  CA    . LEU D 2 324 ? 95.102  43.886  104.411 1.00 28.94  ? 324  LEU B CA    1 
ATOM   9650  C  C     . LEU D 2 324 ? 96.571  44.286  104.368 1.00 28.79  ? 324  LEU B C     1 
ATOM   9651  O  O     . LEU D 2 324 ? 97.202  44.539  105.392 1.00 29.77  ? 324  LEU B O     1 
ATOM   9652  C  CB    . LEU D 2 324 ? 94.999  42.427  104.003 1.00 37.97  ? 324  LEU B CB    1 
ATOM   9653  C  CG    . LEU D 2 324 ? 94.819  41.330  105.029 1.00 39.53  ? 324  LEU B CG    1 
ATOM   9654  C  CD1   . LEU D 2 324 ? 95.159  40.014  104.353 1.00 35.37  ? 324  LEU B CD1   1 
ATOM   9655  C  CD2   . LEU D 2 324 ? 95.696  41.565  106.214 1.00 23.85  ? 324  LEU B CD2   1 
ATOM   9656  N  N     . GLU D 2 325 ? 97.096  44.339  103.153 1.00 27.16  ? 325  GLU B N     1 
ATOM   9657  C  CA    . GLU D 2 325 ? 98.481  44.696  102.898 1.00 29.41  ? 325  GLU B CA    1 
ATOM   9658  C  C     . GLU D 2 325 ? 98.862  46.068  103.435 1.00 28.53  ? 325  GLU B C     1 
ATOM   9659  O  O     . GLU D 2 325 ? 99.937  46.232  104.007 1.00 31.72  ? 325  GLU B O     1 
ATOM   9660  C  CB    . GLU D 2 325 ? 98.775  44.636  101.391 1.00 29.82  ? 325  GLU B CB    1 
ATOM   9661  C  CG    . GLU D 2 325 ? 98.774  43.204  100.833 1.00 30.46  ? 325  GLU B CG    1 
ATOM   9662  C  CD    . GLU D 2 325 ? 97.372  42.620  100.667 1.00 42.73  ? 325  GLU B CD    1 
ATOM   9663  O  OE1   . GLU D 2 325 ? 97.264  41.373  100.602 1.00 42.36  ? 325  GLU B OE1   1 
ATOM   9664  O  OE2   . GLU D 2 325 ? 96.384  43.397  100.591 1.00 27.77  ? 325  GLU B OE2   1 
ATOM   9665  N  N     . GLU D 2 326 ? 98.002  47.059  103.251 1.00 25.36  ? 326  GLU B N     1 
ATOM   9666  C  CA    . GLU D 2 326 ? 98.319  48.384  103.760 1.00 25.48  ? 326  GLU B CA    1 
ATOM   9667  C  C     . GLU D 2 326 ? 98.347  48.358  105.285 1.00 24.70  ? 326  GLU B C     1 
ATOM   9668  O  O     . GLU D 2 326 ? 99.195  48.996  105.887 1.00 30.39  ? 326  GLU B O     1 
ATOM   9669  C  CB    . GLU D 2 326 ? 97.304  49.444  103.294 1.00 33.65  ? 326  GLU B CB    1 
ATOM   9670  C  CG    . GLU D 2 326 ? 97.214  49.624  101.779 1.00 53.51  ? 326  GLU B CG    1 
ATOM   9671  C  CD    . GLU D 2 326 ? 96.113  50.615  101.335 1.00 59.75  ? 326  GLU B CD    1 
ATOM   9672  O  OE1   . GLU D 2 326 ? 94.963  50.546  101.847 1.00 54.18  ? 326  GLU B OE1   1 
ATOM   9673  O  OE2   . GLU D 2 326 ? 96.408  51.453  100.452 1.00 56.67  ? 326  GLU B OE2   1 
ATOM   9674  N  N     . VAL D 2 327 ? 97.423  47.643  105.920 1.00 22.36  ? 327  VAL B N     1 
ATOM   9675  C  CA    . VAL D 2 327 ? 97.452  47.589  107.376 1.00 24.37  ? 327  VAL B CA    1 
ATOM   9676  C  C     . VAL D 2 327 ? 98.758  46.889  107.838 1.00 26.38  ? 327  VAL B C     1 
ATOM   9677  O  O     . VAL D 2 327 ? 99.418  47.328  108.787 1.00 27.55  ? 327  VAL B O     1 
ATOM   9678  C  CB    . VAL D 2 327 ? 96.226  46.842  107.943 1.00 20.49  ? 327  VAL B CB    1 
ATOM   9679  C  CG1   . VAL D 2 327 ? 96.387  46.671  109.429 1.00 18.70  ? 327  VAL B CG1   1 
ATOM   9680  C  CG2   . VAL D 2 327 ? 94.950  47.643  107.689 1.00 14.42  ? 327  VAL B CG2   1 
ATOM   9681  N  N     . ALA D 2 328 ? 99.142  45.822  107.148 1.00 22.29  ? 328  ALA B N     1 
ATOM   9682  C  CA    . ALA D 2 328 ? 100.344 45.092  107.519 1.00 25.60  ? 328  ALA B CA    1 
ATOM   9683  C  C     . ALA D 2 328 ? 101.548 45.996  107.455 1.00 30.76  ? 328  ALA B C     1 
ATOM   9684  O  O     . ALA D 2 328 ? 102.392 45.920  108.348 1.00 30.92  ? 328  ALA B O     1 
ATOM   9685  C  CB    . ALA D 2 328 ? 100.541 43.878  106.624 1.00 15.33  ? 328  ALA B CB    1 
ATOM   9686  N  N     . GLU D 2 329 ? 101.611 46.859  106.431 1.00 23.17  ? 329  GLU B N     1 
ATOM   9687  C  CA    . GLU D 2 329 ? 102.729 47.792  106.280 1.00 25.19  ? 329  GLU B CA    1 
ATOM   9688  C  C     . GLU D 2 329 ? 102.788 48.808  107.408 1.00 30.71  ? 329  GLU B C     1 
ATOM   9689  O  O     . GLU D 2 329 ? 103.851 49.089  107.952 1.00 33.66  ? 329  GLU B O     1 
ATOM   9690  C  CB    . GLU D 2 329 ? 102.633 48.586  104.968 1.00 21.58  ? 329  GLU B CB    1 
ATOM   9691  C  CG    . GLU D 2 329 ? 103.111 47.846  103.739 1.00 42.37  ? 329  GLU B CG    1 
ATOM   9692  C  CD    . GLU D 2 329 ? 104.367 47.007  103.998 1.00 57.58  ? 329  GLU B CD    1 
ATOM   9693  O  OE1   . GLU D 2 329 ? 105.413 47.597  104.389 1.00 53.69  ? 329  GLU B OE1   1 
ATOM   9694  O  OE2   . GLU D 2 329 ? 104.290 45.756  103.812 1.00 54.81  ? 329  GLU B OE2   1 
ATOM   9695  N  N     . ARG D 2 330 ? 101.627 49.356  107.750 1.00 25.75  ? 330  ARG B N     1 
ATOM   9696  C  CA    . ARG D 2 330 ? 101.516 50.380  108.764 1.00 23.60  ? 330  ARG B CA    1 
ATOM   9697  C  C     . ARG D 2 330 ? 101.774 49.895  110.182 1.00 30.84  ? 330  ARG B C     1 
ATOM   9698  O  O     . ARG D 2 330 ? 102.168 50.654  111.074 1.00 40.41  ? 330  ARG B O     1 
ATOM   9699  C  CB    . ARG D 2 330 ? 100.131 51.024  108.644 1.00 25.03  ? 330  ARG B CB    1 
ATOM   9700  C  CG    . ARG D 2 330 ? 99.914  51.713  107.275 1.00 27.92  ? 330  ARG B CG    1 
ATOM   9701  C  CD    . ARG D 2 330 ? 98.552  52.345  107.151 1.00 24.89  ? 330  ARG B CD    1 
ATOM   9702  N  NE    . ARG D 2 330 ? 98.363  53.069  105.892 1.00 27.66  ? 330  ARG B NE    1 
ATOM   9703  C  CZ    . ARG D 2 330 ? 97.671  54.206  105.776 1.00 31.59  ? 330  ARG B CZ    1 
ATOM   9704  N  NH1   . ARG D 2 330 ? 97.119  54.773  106.844 1.00 28.89  ? 330  ARG B NH1   1 
ATOM   9705  N  NH2   . ARG D 2 330 ? 97.463  54.743  104.578 1.00 34.72  ? 330  ARG B NH2   1 
ATOM   9706  N  N     . VAL D 2 331 ? 101.557 48.616  110.377 1.00 20.58  ? 331  VAL B N     1 
ATOM   9707  C  CA    . VAL D 2 331 ? 101.742 47.976  111.655 1.00 20.34  ? 331  VAL B CA    1 
ATOM   9708  C  C     . VAL D 2 331 ? 103.251 47.837  112.015 1.00 23.45  ? 331  VAL B C     1 
ATOM   9709  O  O     . VAL D 2 331 ? 103.635 47.848  113.176 1.00 31.23  ? 331  VAL B O     1 
ATOM   9710  C  CB    . VAL D 2 331 ? 101.015 46.593  111.541 1.00 28.22  ? 331  VAL B CB    1 
ATOM   9711  C  CG1   . VAL D 2 331 ? 101.721 45.562  112.304 1.00 25.31  ? 331  VAL B CG1   1 
ATOM   9712  C  CG2   . VAL D 2 331 ? 99.536  46.731  111.964 1.00 23.73  ? 331  VAL B CG2   1 
ATOM   9713  N  N     . LYS D 2 332 ? 104.102 47.738  111.002 1.00 29.05  ? 332  LYS B N     1 
ATOM   9714  C  CA    . LYS D 2 332 ? 105.538 47.547  111.195 1.00 32.17  ? 332  LYS B CA    1 
ATOM   9715  C  C     . LYS D 2 332 ? 106.285 48.486  112.150 1.00 33.77  ? 332  LYS B C     1 
ATOM   9716  O  O     . LYS D 2 332 ? 107.059 48.029  112.999 1.00 30.05  ? 332  LYS B O     1 
ATOM   9717  C  CB    . LYS D 2 332 ? 106.242 47.532  109.833 1.00 28.43  ? 332  LYS B CB    1 
ATOM   9718  C  CG    . LYS D 2 332 ? 105.930 46.267  109.017 1.00 29.08  ? 332  LYS B CG    1 
ATOM   9719  C  CD    . LYS D 2 332 ? 106.619 46.295  107.657 1.00 25.48  ? 332  LYS B CD    1 
ATOM   9720  C  CE    . LYS D 2 332 ? 106.268 45.058  106.828 1.00 27.09  ? 332  LYS B CE    1 
ATOM   9721  N  NZ    . LYS D 2 332 ? 106.793 45.153  105.446 1.00 28.97  ? 332  LYS B NZ    1 
ATOM   9722  N  N     . PRO D 2 333 ? 106.093 49.804  112.020 1.00 28.17  ? 333  PRO B N     1 
ATOM   9723  C  CA    . PRO D 2 333 ? 106.898 50.499  113.020 1.00 26.28  ? 333  PRO B CA    1 
ATOM   9724  C  C     . PRO D 2 333 ? 106.444 50.308  114.458 1.00 35.55  ? 333  PRO B C     1 
ATOM   9725  O  O     . PRO D 2 333 ? 107.229 50.528  115.375 1.00 30.99  ? 333  PRO B O     1 
ATOM   9726  C  CB    . PRO D 2 333 ? 106.883 51.957  112.562 1.00 27.43  ? 333  PRO B CB    1 
ATOM   9727  C  CG    . PRO D 2 333 ? 105.852 52.014  111.478 1.00 35.80  ? 333  PRO B CG    1 
ATOM   9728  C  CD    . PRO D 2 333 ? 105.835 50.663  110.858 1.00 28.37  ? 333  PRO B CD    1 
ATOM   9729  N  N     . PHE D 2 334 ? 105.201 49.881  114.666 1.00 32.35  ? 334  PHE B N     1 
ATOM   9730  C  CA    . PHE D 2 334 ? 104.740 49.683  116.026 1.00 33.42  ? 334  PHE B CA    1 
ATOM   9731  C  C     . PHE D 2 334 ? 105.283 48.354  116.549 1.00 31.25  ? 334  PHE B C     1 
ATOM   9732  O  O     . PHE D 2 334 ? 105.550 48.199  117.737 1.00 37.44  ? 334  PHE B O     1 
ATOM   9733  C  CB    . PHE D 2 334 ? 103.200 49.793  116.086 1.00 30.28  ? 334  PHE B CB    1 
ATOM   9734  C  CG    . PHE D 2 334 ? 102.702 51.198  115.820 1.00 31.92  ? 334  PHE B CG    1 
ATOM   9735  C  CD1   . PHE D 2 334 ? 102.619 52.127  116.853 1.00 26.56  ? 334  PHE B CD1   1 
ATOM   9736  C  CD2   . PHE D 2 334 ? 102.479 51.635  114.519 1.00 15.42  ? 334  PHE B CD2   1 
ATOM   9737  C  CE1   . PHE D 2 334 ? 102.345 53.473  116.587 1.00 26.51  ? 334  PHE B CE1   1 
ATOM   9738  C  CE2   . PHE D 2 334 ? 102.198 52.979  114.245 1.00 17.83  ? 334  PHE B CE2   1 
ATOM   9739  C  CZ    . PHE D 2 334 ? 102.138 53.897  115.281 1.00 20.84  ? 334  PHE B CZ    1 
ATOM   9740  N  N     . LEU D 2 335 ? 105.466 47.396  115.661 1.00 30.36  ? 335  LEU B N     1 
ATOM   9741  C  CA    . LEU D 2 335 ? 106.034 46.128  116.088 1.00 29.62  ? 335  LEU B CA    1 
ATOM   9742  C  C     . LEU D 2 335 ? 107.524 46.400  116.386 1.00 35.20  ? 335  LEU B C     1 
ATOM   9743  O  O     . LEU D 2 335 ? 108.067 45.881  117.355 1.00 31.19  ? 335  LEU B O     1 
ATOM   9744  C  CB    . LEU D 2 335 ? 105.907 45.076  114.980 1.00 23.06  ? 335  LEU B CB    1 
ATOM   9745  C  CG    . LEU D 2 335 ? 104.532 44.470  114.669 1.00 22.65  ? 335  LEU B CG    1 
ATOM   9746  C  CD1   . LEU D 2 335 ? 104.536 43.809  113.306 1.00 23.99  ? 335  LEU B CD1   1 
ATOM   9747  C  CD2   . LEU D 2 335 ? 104.197 43.445  115.740 1.00 18.80  ? 335  LEU B CD2   1 
ATOM   9748  N  N     . ARG D 2 336 ? 108.176 47.215  115.558 1.00 27.98  ? 336  ARG B N     1 
ATOM   9749  C  CA    . ARG D 2 336 ? 109.596 47.512  115.774 1.00 38.81  ? 336  ARG B CA    1 
ATOM   9750  C  C     . ARG D 2 336 ? 109.773 48.230  117.096 1.00 40.41  ? 336  ARG B C     1 
ATOM   9751  O  O     . ARG D 2 336 ? 110.641 47.881  117.893 1.00 44.74  ? 336  ARG B O     1 
ATOM   9752  C  CB    . ARG D 2 336 ? 110.195 48.358  114.629 1.00 38.03  ? 336  ARG B CB    1 
ATOM   9753  C  CG    . ARG D 2 336 ? 110.380 47.571  113.331 1.00 45.91  ? 336  ARG B CG    1 
ATOM   9754  C  CD    . ARG D 2 336 ? 111.598 47.997  112.508 1.00 57.32  ? 336  ARG B CD    1 
ATOM   9755  N  NE    . ARG D 2 336 ? 111.917 46.997  111.481 1.00 70.10  ? 336  ARG B NE    1 
ATOM   9756  C  CZ    . ARG D 2 336 ? 111.313 46.924  110.295 1.00 70.82  ? 336  ARG B CZ    1 
ATOM   9757  N  NH1   . ARG D 2 336 ? 110.373 47.811  109.998 1.00 62.69  ? 336  ARG B NH1   1 
ATOM   9758  N  NH2   . ARG D 2 336 ? 111.620 45.955  109.422 1.00 54.79  ? 336  ARG B NH2   1 
ATOM   9759  N  N     . GLU D 2 337 ? 108.919 49.212  117.335 1.00 43.00  ? 337  GLU B N     1 
ATOM   9760  C  CA    . GLU D 2 337 ? 108.955 49.993  118.566 1.00 46.32  ? 337  GLU B CA    1 
ATOM   9761  C  C     . GLU D 2 337 ? 108.701 49.116  119.821 1.00 45.00  ? 337  GLU B C     1 
ATOM   9762  O  O     . GLU D 2 337 ? 109.216 49.403  120.903 1.00 43.44  ? 337  GLU B O     1 
ATOM   9763  C  CB    . GLU D 2 337 ? 107.941 51.136  118.425 1.00 40.28  ? 337  GLU B CB    1 
ATOM   9764  C  CG    . GLU D 2 337 ? 107.640 51.967  119.659 1.00 54.74  ? 337  GLU B CG    1 
ATOM   9765  C  CD    . GLU D 2 337 ? 106.456 52.904  119.405 1.00 67.63  ? 337  GLU B CD    1 
ATOM   9766  O  OE1   . GLU D 2 337 ? 106.659 53.960  118.760 1.00 75.79  ? 337  GLU B OE1   1 
ATOM   9767  O  OE2   . GLU D 2 337 ? 105.318 52.574  119.821 1.00 60.14  ? 337  GLU B OE2   1 
ATOM   9768  N  N     . ALA D 2 338 ? 107.926 48.044  119.677 1.00 35.70  ? 338  ALA B N     1 
ATOM   9769  C  CA    . ALA D 2 338 ? 107.670 47.162  120.808 1.00 34.23  ? 338  ALA B CA    1 
ATOM   9770  C  C     . ALA D 2 338 ? 108.796 46.119  120.945 1.00 34.34  ? 338  ALA B C     1 
ATOM   9771  O  O     . ALA D 2 338 ? 108.771 45.273  121.845 1.00 32.55  ? 338  ALA B O     1 
ATOM   9772  C  CB    . ALA D 2 338 ? 106.335 46.462  120.626 1.00 34.96  ? 338  ALA B CB    1 
ATOM   9773  N  N     . GLY D 2 339 ? 109.778 46.193  120.050 1.00 30.02  ? 339  GLY B N     1 
ATOM   9774  C  CA    . GLY D 2 339 ? 110.881 45.250  120.075 1.00 33.30  ? 339  GLY B CA    1 
ATOM   9775  C  C     . GLY D 2 339 ? 110.537 43.871  119.529 1.00 39.57  ? 339  GLY B C     1 
ATOM   9776  O  O     . GLY D 2 339 ? 111.205 42.896  119.851 1.00 45.09  ? 339  GLY B O     1 
ATOM   9777  N  N     . LEU D 2 340 ? 109.501 43.788  118.701 1.00 36.95  ? 340  LEU B N     1 
ATOM   9778  C  CA    . LEU D 2 340 ? 109.067 42.516  118.106 1.00 36.21  ? 340  LEU B CA    1 
ATOM   9779  C  C     . LEU D 2 340 ? 109.407 42.451  116.613 1.00 32.28  ? 340  LEU B C     1 
ATOM   9780  O  O     . LEU D 2 340 ? 109.438 43.472  115.928 1.00 34.75  ? 340  LEU B O     1 
ATOM   9781  C  CB    . LEU D 2 340 ? 107.563 42.368  118.258 1.00 19.40  ? 340  LEU B CB    1 
ATOM   9782  C  CG    . LEU D 2 340 ? 106.993 42.453  119.673 1.00 28.21  ? 340  LEU B CG    1 
ATOM   9783  C  CD1   . LEU D 2 340 ? 105.471 42.554  119.597 1.00 21.07  ? 340  LEU B CD1   1 
ATOM   9784  C  CD2   . LEU D 2 340 ? 107.409 41.200  120.461 1.00 19.03  ? 340  LEU B CD2   1 
ATOM   9785  N  N     . SER D 2 341 ? 109.669 41.251  116.122 1.00 28.72  ? 341  SER B N     1 
ATOM   9786  C  CA    . SER D 2 341 ? 109.960 41.057  114.718 1.00 33.36  ? 341  SER B CA    1 
ATOM   9787  C  C     . SER D 2 341 ? 108.995 39.987  114.177 1.00 35.12  ? 341  SER B C     1 
ATOM   9788  O  O     . SER D 2 341 ? 108.335 39.287  114.947 1.00 40.67  ? 341  SER B O     1 
ATOM   9789  C  CB    . SER D 2 341 ? 111.398 40.593  114.545 1.00 37.99  ? 341  SER B CB    1 
ATOM   9790  O  OG    . SER D 2 341 ? 111.540 39.293  115.067 1.00 46.94  ? 341  SER B OG    1 
ATOM   9791  N  N     . TRP D 2 342 ? 108.924 39.860  112.858 1.00 32.63  ? 342  TRP B N     1 
ATOM   9792  C  CA    . TRP D 2 342 ? 108.048 38.893  112.206 1.00 30.93  ? 342  TRP B CA    1 
ATOM   9793  C  C     . TRP D 2 342 ? 108.915 38.014  111.308 1.00 31.76  ? 342  TRP B C     1 
ATOM   9794  O  O     . TRP D 2 342 ? 109.878 38.496  110.706 1.00 37.89  ? 342  TRP B O     1 
ATOM   9795  C  CB    . TRP D 2 342 ? 107.009 39.653  111.401 1.00 23.60  ? 342  TRP B CB    1 
ATOM   9796  C  CG    . TRP D 2 342 ? 107.604 40.706  110.532 1.00 25.30  ? 342  TRP B CG    1 
ATOM   9797  C  CD1   . TRP D 2 342 ? 107.820 40.630  109.181 1.00 25.77  ? 342  TRP B CD1   1 
ATOM   9798  C  CD2   . TRP D 2 342 ? 107.972 42.033  110.922 1.00 27.30  ? 342  TRP B CD2   1 
ATOM   9799  N  NE1   . TRP D 2 342 ? 108.278 41.838  108.699 1.00 23.12  ? 342  TRP B NE1   1 
ATOM   9800  C  CE2   . TRP D 2 342 ? 108.379 42.720  109.743 1.00 31.25  ? 342  TRP B CE2   1 
ATOM   9801  C  CE3   . TRP D 2 342 ? 107.988 42.715  112.142 1.00 25.91  ? 342  TRP B CE3   1 
ATOM   9802  C  CZ2   . TRP D 2 342 ? 108.792 44.064  109.753 1.00 21.62  ? 342  TRP B CZ2   1 
ATOM   9803  C  CZ3   . TRP D 2 342 ? 108.398 44.049  112.157 1.00 25.72  ? 342  TRP B CZ3   1 
ATOM   9804  C  CH2   . TRP D 2 342 ? 108.792 44.710  110.961 1.00 32.25  ? 342  TRP B CH2   1 
ATOM   9805  N  N     . GLU D 2 343 ? 108.582 36.736  111.184 1.00 28.97  ? 343  GLU B N     1 
ATOM   9806  C  CA    . GLU D 2 343 ? 109.433 35.850  110.399 1.00 35.65  ? 343  GLU B CA    1 
ATOM   9807  C  C     . GLU D 2 343 ? 109.431 36.088  108.896 1.00 35.63  ? 343  GLU B C     1 
ATOM   9808  O  O     . GLU D 2 343 ? 110.438 35.834  108.223 1.00 30.95  ? 343  GLU B O     1 
ATOM   9809  C  CB    . GLU D 2 343 ? 109.105 34.378  110.696 1.00 33.64  ? 343  GLU B CB    1 
ATOM   9810  C  CG    . GLU D 2 343 ? 108.007 33.763  109.859 1.00 47.41  ? 343  GLU B CG    1 
ATOM   9811  C  CD    . GLU D 2 343 ? 107.774 32.299  110.218 1.00 54.79  ? 343  GLU B CD    1 
ATOM   9812  O  OE1   . GLU D 2 343 ? 107.114 31.578  109.435 1.00 58.50  ? 343  GLU B OE1   1 
ATOM   9813  O  OE2   . GLU D 2 343 ? 108.245 31.872  111.293 1.00 55.97  ? 343  GLU B OE2   1 
ATOM   9814  N  N     . SER D 2 344 ? 108.317 36.591  108.376 1.00 29.30  ? 344  SER B N     1 
ATOM   9815  C  CA    . SER D 2 344 ? 108.194 36.820  106.945 1.00 33.01  ? 344  SER B CA    1 
ATOM   9816  C  C     . SER D 2 344 ? 107.000 37.714  106.640 1.00 34.07  ? 344  SER B C     1 
ATOM   9817  O  O     . SER D 2 344 ? 106.134 37.928  107.498 1.00 43.91  ? 344  SER B O     1 
ATOM   9818  C  CB    . SER D 2 344 ? 107.975 35.476  106.259 1.00 22.08  ? 344  SER B CB    1 
ATOM   9819  O  OG    . SER D 2 344 ? 106.705 34.971  106.653 1.00 37.97  ? 344  SER B OG    1 
ATOM   9820  N  N     . GLU D 2 345 ? 106.935 38.219  105.417 1.00 28.56  ? 345  GLU B N     1 
ATOM   9821  C  CA    . GLU D 2 345 ? 105.805 39.056  105.041 1.00 30.38  ? 345  GLU B CA    1 
ATOM   9822  C  C     . GLU D 2 345 ? 104.553 38.208  105.078 1.00 25.96  ? 345  GLU B C     1 
ATOM   9823  O  O     . GLU D 2 345 ? 103.510 38.638  105.541 1.00 33.02  ? 345  GLU B O     1 
ATOM   9824  C  CB    . GLU D 2 345 ? 106.015 39.624  103.649 1.00 34.95  ? 345  GLU B CB    1 
ATOM   9825  C  CG    . GLU D 2 345 ? 107.138 40.645  103.635 1.00 41.44  ? 345  GLU B CG    1 
ATOM   9826  C  CD    . GLU D 2 345 ? 106.720 41.909  104.326 1.00 47.36  ? 345  GLU B CD    1 
ATOM   9827  O  OE1   . GLU D 2 345 ? 107.512 42.447  105.122 1.00 53.95  ? 345  GLU B OE1   1 
ATOM   9828  O  OE2   . GLU D 2 345 ? 105.585 42.361  104.066 1.00 53.01  ? 345  GLU B OE2   1 
ATOM   9829  N  N     . ALA D 2 346 ? 104.660 36.978  104.607 1.00 24.97  ? 346  ALA B N     1 
ATOM   9830  C  CA    . ALA D 2 346 ? 103.503 36.121  104.610 1.00 23.15  ? 346  ALA B CA    1 
ATOM   9831  C  C     . ALA D 2 346 ? 102.998 35.928  106.042 1.00 27.27  ? 346  ALA B C     1 
ATOM   9832  O  O     . ALA D 2 346 ? 101.810 35.965  106.290 1.00 33.19  ? 346  ALA B O     1 
ATOM   9833  C  CB    . ALA D 2 346 ? 103.836 34.786  103.983 1.00 11.51  ? 346  ALA B CB    1 
ATOM   9834  N  N     . TYR D 2 347 ? 103.905 35.742  106.991 1.00 31.31  ? 347  TYR B N     1 
ATOM   9835  C  CA    . TYR D 2 347 ? 103.490 35.522  108.363 1.00 21.80  ? 347  TYR B CA    1 
ATOM   9836  C  C     . TYR D 2 347 ? 102.794 36.757  108.911 1.00 28.44  ? 347  TYR B C     1 
ATOM   9837  O  O     . TYR D 2 347 ? 101.692 36.674  109.456 1.00 20.53  ? 347  TYR B O     1 
ATOM   9838  C  CB    . TYR D 2 347 ? 104.705 35.182  109.231 1.00 24.12  ? 347  TYR B CB    1 
ATOM   9839  C  CG    . TYR D 2 347 ? 104.313 34.773  110.622 1.00 20.78  ? 347  TYR B CG    1 
ATOM   9840  C  CD1   . TYR D 2 347 ? 104.058 33.432  110.940 1.00 19.57  ? 347  TYR B CD1   1 
ATOM   9841  C  CD2   . TYR D 2 347 ? 104.150 35.723  111.609 1.00 14.64  ? 347  TYR B CD2   1 
ATOM   9842  C  CE1   . TYR D 2 347 ? 103.653 33.079  112.206 1.00 16.69  ? 347  TYR B CE1   1 
ATOM   9843  C  CE2   . TYR D 2 347 ? 103.744 35.379  112.881 1.00 22.35  ? 347  TYR B CE2   1 
ATOM   9844  C  CZ    . TYR D 2 347 ? 103.495 34.067  113.179 1.00 24.22  ? 347  TYR B CZ    1 
ATOM   9845  O  OH    . TYR D 2 347 ? 103.066 33.769  114.456 1.00 29.13  ? 347  TYR B OH    1 
ATOM   9846  N  N     . LEU D 2 348 ? 103.441 37.908  108.767 1.00 23.18  ? 348  LEU B N     1 
ATOM   9847  C  CA    . LEU D 2 348 ? 102.849 39.140  109.261 1.00 23.35  ? 348  LEU B CA    1 
ATOM   9848  C  C     . LEU D 2 348 ? 101.456 39.368  108.662 1.00 30.78  ? 348  LEU B C     1 
ATOM   9849  O  O     . LEU D 2 348 ? 100.516 39.737  109.368 1.00 27.30  ? 348  LEU B O     1 
ATOM   9850  C  CB    . LEU D 2 348 ? 103.720 40.337  108.918 1.00 17.22  ? 348  LEU B CB    1 
ATOM   9851  C  CG    . LEU D 2 348 ? 103.155 41.651  109.450 1.00 21.26  ? 348  LEU B CG    1 
ATOM   9852  C  CD1   . LEU D 2 348 ? 103.121 41.610  110.998 1.00 15.56  ? 348  LEU B CD1   1 
ATOM   9853  C  CD2   . LEU D 2 348 ? 103.996 42.802  108.951 1.00 10.90  ? 348  LEU B CD2   1 
ATOM   9854  N  N     . ARG D 2 349 ? 101.320 39.135  107.363 1.00 24.98  ? 349  ARG B N     1 
ATOM   9855  C  CA    . ARG D 2 349 ? 100.048 39.367  106.693 1.00 28.87  ? 349  ARG B CA    1 
ATOM   9856  C  C     . ARG D 2 349 ? 98.949  38.533  107.307 1.00 24.25  ? 349  ARG B C     1 
ATOM   9857  O  O     . ARG D 2 349 ? 97.855  39.016  107.548 1.00 30.00  ? 349  ARG B O     1 
ATOM   9858  C  CB    . ARG D 2 349 ? 100.174 39.067  105.204 1.00 31.47  ? 349  ARG B CB    1 
ATOM   9859  C  CG    . ARG D 2 349 ? 98.936  39.351  104.374 1.00 28.66  ? 349  ARG B CG    1 
ATOM   9860  C  CD    . ARG D 2 349 ? 99.153  38.979  102.877 1.00 28.76  ? 349  ARG B CD    1 
ATOM   9861  N  NE    . ARG D 2 349 ? 100.141 39.848  102.240 1.00 33.41  ? 349  ARG B NE    1 
ATOM   9862  C  CZ    . ARG D 2 349 ? 100.488 39.800  100.953 1.00 41.47  ? 349  ARG B CZ    1 
ATOM   9863  N  NH1   . ARG D 2 349 ? 101.392 40.652  100.487 1.00 38.03  ? 349  ARG B NH1   1 
ATOM   9864  N  NH2   . ARG D 2 349 ? 99.946  38.908  100.126 1.00 35.25  ? 349  ARG B NH2   1 
ATOM   9865  N  N     . ARG D 2 350 ? 99.246  37.280  107.569 1.00 19.43  ? 350  ARG B N     1 
ATOM   9866  C  CA    . ARG D 2 350 ? 98.272  36.408  108.160 1.00 25.50  ? 350  ARG B CA    1 
ATOM   9867  C  C     . ARG D 2 350 ? 97.986  36.820  109.619 1.00 27.04  ? 350  ARG B C     1 
ATOM   9868  O  O     . ARG D 2 350 ? 96.846  36.822  110.087 1.00 24.93  ? 350  ARG B O     1 
ATOM   9869  C  CB    . ARG D 2 350 ? 98.788  34.985  108.089 1.00 29.69  ? 350  ARG B CB    1 
ATOM   9870  C  CG    . ARG D 2 350 ? 97.845  33.977  108.705 1.00 43.49  ? 350  ARG B CG    1 
ATOM   9871  C  CD    . ARG D 2 350 ? 96.477  34.037  108.069 1.00 32.82  ? 350  ARG B CD    1 
ATOM   9872  N  NE    . ARG D 2 350 ? 95.690  32.882  108.472 1.00 41.54  ? 350  ARG B NE    1 
ATOM   9873  C  CZ    . ARG D 2 350 ? 94.376  32.792  108.323 1.00 37.83  ? 350  ARG B CZ    1 
ATOM   9874  N  NH1   . ARG D 2 350 ? 93.699  33.797  107.779 1.00 34.33  ? 350  ARG B NH1   1 
ATOM   9875  N  NH2   . ARG D 2 350 ? 93.737  31.702  108.729 1.00 42.17  ? 350  ARG B NH2   1 
ATOM   9876  N  N     . ALA D 2 351 ? 99.022  37.183  110.348 1.00 26.77  ? 351  ALA B N     1 
ATOM   9877  C  CA    . ALA D 2 351 ? 98.799  37.579  111.713 1.00 26.34  ? 351  ALA B CA    1 
ATOM   9878  C  C     . ALA D 2 351 ? 97.858  38.792  111.726 1.00 27.78  ? 351  ALA B C     1 
ATOM   9879  O  O     . ALA D 2 351 ? 96.900  38.824  112.493 1.00 28.07  ? 351  ALA B O     1 
ATOM   9880  C  CB    . ALA D 2 351 ? 100.133 37.910  112.395 1.00 25.60  ? 351  ALA B CB    1 
ATOM   9881  N  N     . VAL D 2 352 ? 98.113  39.770  110.863 1.00 23.77  ? 352  VAL B N     1 
ATOM   9882  C  CA    . VAL D 2 352 ? 97.300  40.982  110.806 1.00 22.02  ? 352  VAL B CA    1 
ATOM   9883  C  C     . VAL D 2 352 ? 95.882  40.650  110.395 1.00 26.12  ? 352  VAL B C     1 
ATOM   9884  O  O     . VAL D 2 352 ? 94.930  41.245  110.876 1.00 24.53  ? 352  VAL B O     1 
ATOM   9885  C  CB    . VAL D 2 352 ? 97.862  42.007  109.793 1.00 30.83  ? 352  VAL B CB    1 
ATOM   9886  C  CG1   . VAL D 2 352 ? 96.853  43.189  109.582 1.00 18.44  ? 352  VAL B CG1   1 
ATOM   9887  C  CG2   . VAL D 2 352 ? 99.206  42.522  110.290 1.00 24.64  ? 352  VAL B CG2   1 
ATOM   9888  N  N     . GLU D 2 353 ? 95.737  39.682  109.507 1.00 26.37  ? 353  GLU B N     1 
ATOM   9889  C  CA    . GLU D 2 353 ? 94.417  39.291  109.049 1.00 19.64  ? 353  GLU B CA    1 
ATOM   9890  C  C     . GLU D 2 353 ? 93.579  38.724  110.205 1.00 19.77  ? 353  GLU B C     1 
ATOM   9891  O  O     . GLU D 2 353 ? 92.435  39.089  110.377 1.00 28.92  ? 353  GLU B O     1 
ATOM   9892  C  CB    . GLU D 2 353 ? 94.546  38.256  107.928 1.00 29.04  ? 353  GLU B CB    1 
ATOM   9893  C  CG    . GLU D 2 353 ? 93.203  37.916  107.255 1.00 40.66  ? 353  GLU B CG    1 
ATOM   9894  C  CD    . GLU D 2 353 ? 93.357  36.918  106.124 1.00 48.41  ? 353  GLU B CD    1 
ATOM   9895  O  OE1   . GLU D 2 353 ? 92.601  37.025  105.126 1.00 55.30  ? 353  GLU B OE1   1 
ATOM   9896  O  OE2   . GLU D 2 353 ? 94.234  36.029  106.235 1.00 51.35  ? 353  GLU B OE2   1 
ATOM   9897  N  N     . LEU D 2 354 ? 94.160  37.837  110.997 1.00 20.99  ? 354  LEU B N     1 
ATOM   9898  C  CA    . LEU D 2 354 ? 93.470  37.222  112.130 1.00 24.91  ? 354  LEU B CA    1 
ATOM   9899  C  C     . LEU D 2 354 ? 93.081  38.246  113.187 1.00 21.21  ? 354  LEU B C     1 
ATOM   9900  O  O     . LEU D 2 354 ? 92.092  38.105  113.883 1.00 31.85  ? 354  LEU B O     1 
ATOM   9901  C  CB    . LEU D 2 354 ? 94.378  36.150  112.761 1.00 19.99  ? 354  LEU B CB    1 
ATOM   9902  C  CG    . LEU D 2 354 ? 94.618  34.954  111.836 1.00 30.53  ? 354  LEU B CG    1 
ATOM   9903  C  CD1   . LEU D 2 354 ? 95.623  33.993  112.449 1.00 20.48  ? 354  LEU B CD1   1 
ATOM   9904  C  CD2   . LEU D 2 354 ? 93.245  34.250  111.554 1.00 22.12  ? 354  LEU B CD2   1 
ATOM   9905  N  N     . MET D 2 355 ? 93.850  39.305  113.249 1.00 26.83  ? 355  MET B N     1 
ATOM   9906  C  CA    . MET D 2 355 ? 93.692  40.343  114.230 1.00 26.38  ? 355  MET B CA    1 
ATOM   9907  C  C     . MET D 2 355 ? 92.920  41.576  113.772 1.00 30.27  ? 355  MET B C     1 
ATOM   9908  O  O     . MET D 2 355 ? 92.512  42.394  114.613 1.00 30.40  ? 355  MET B O     1 
ATOM   9909  C  CB    . MET D 2 355 ? 95.098  40.731  114.649 1.00 26.67  ? 355  MET B CB    1 
ATOM   9910  C  CG    . MET D 2 355 ? 95.396  40.702  116.124 1.00 48.84  ? 355  MET B CG    1 
ATOM   9911  S  SD    . MET D 2 355 ? 94.864  39.298  117.125 1.00 30.93  ? 355  MET B SD    1 
ATOM   9912  C  CE    . MET D 2 355 ? 94.612  40.292  118.592 1.00 34.30  ? 355  MET B CE    1 
ATOM   9913  N  N     . ARG D 2 356 ? 92.694  41.707  112.466 1.00 27.62  ? 356  ARG B N     1 
ATOM   9914  C  CA    . ARG D 2 356 ? 92.020  42.900  111.950 1.00 27.33  ? 356  ARG B CA    1 
ATOM   9915  C  C     . ARG D 2 356 ? 90.761  43.356  112.707 1.00 31.34  ? 356  ARG B C     1 
ATOM   9916  O  O     . ARG D 2 356 ? 90.604  44.539  113.010 1.00 26.58  ? 356  ARG B O     1 
ATOM   9917  C  CB    . ARG D 2 356 ? 91.718  42.747  110.464 1.00 34.00  ? 356  ARG B CB    1 
ATOM   9918  C  CG    . ARG D 2 356 ? 92.780  43.386  109.604 1.00 42.73  ? 356  ARG B CG    1 
ATOM   9919  C  CD    . ARG D 2 356 ? 92.212  44.401  108.606 1.00 51.29  ? 356  ARG B CD    1 
ATOM   9920  N  NE    . ARG D 2 356 ? 91.728  43.764  107.391 1.00 38.25  ? 356  ARG B NE    1 
ATOM   9921  C  CZ    . ARG D 2 356 ? 91.398  44.405  106.276 1.00 35.91  ? 356  ARG B CZ    1 
ATOM   9922  N  NH1   . ARG D 2 356 ? 91.489  45.724  106.194 1.00 32.92  ? 356  ARG B NH1   1 
ATOM   9923  N  NH2   . ARG D 2 356 ? 90.986  43.709  105.226 1.00 31.49  ? 356  ARG B NH2   1 
ATOM   9924  N  N     . PRO D 2 357 ? 89.858  42.428  113.037 1.00 21.44  ? 357  PRO B N     1 
ATOM   9925  C  CA    . PRO D 2 357 ? 88.709  42.968  113.750 1.00 22.20  ? 357  PRO B CA    1 
ATOM   9926  C  C     . PRO D 2 357 ? 88.964  43.167  115.238 1.00 31.11  ? 357  PRO B C     1 
ATOM   9927  O  O     . PRO D 2 357 ? 88.031  43.475  115.980 1.00 34.33  ? 357  PRO B O     1 
ATOM   9928  C  CB    . PRO D 2 357 ? 87.593  41.939  113.477 1.00 15.14  ? 357  PRO B CB    1 
ATOM   9929  C  CG    . PRO D 2 357 ? 88.311  40.633  113.018 1.00 9.99   ? 357  PRO B CG    1 
ATOM   9930  C  CD    . PRO D 2 357 ? 89.796  40.960  112.871 1.00 22.50  ? 357  PRO B CD    1 
ATOM   9931  N  N     . ARG D 2 358 ? 90.213  43.037  115.687 1.00 29.83  ? 358  ARG B N     1 
ATOM   9932  C  CA    . ARG D 2 358 ? 90.464  43.159  117.121 1.00 25.06  ? 358  ARG B CA    1 
ATOM   9933  C  C     . ARG D 2 358 ? 91.334  44.302  117.640 1.00 32.83  ? 358  ARG B C     1 
ATOM   9934  O  O     . ARG D 2 358 ? 91.691  44.293  118.817 1.00 37.28  ? 358  ARG B O     1 
ATOM   9935  C  CB    . ARG D 2 358 ? 90.980  41.805  117.681 1.00 19.88  ? 358  ARG B CB    1 
ATOM   9936  C  CG    . ARG D 2 358 ? 89.977  40.646  117.471 1.00 26.10  ? 358  ARG B CG    1 
ATOM   9937  C  CD    . ARG D 2 358 ? 90.559  39.235  117.619 1.00 20.64  ? 358  ARG B CD    1 
ATOM   9938  N  NE    . ARG D 2 358 ? 89.456  38.267  117.626 1.00 34.42  ? 358  ARG B NE    1 
ATOM   9939  C  CZ    . ARG D 2 358 ? 88.954  37.652  116.556 1.00 30.84  ? 358  ARG B CZ    1 
ATOM   9940  N  NH1   . ARG D 2 358 ? 89.462  37.856  115.354 1.00 27.93  ? 358  ARG B NH1   1 
ATOM   9941  N  NH2   . ARG D 2 358 ? 87.863  36.902  116.673 1.00 29.37  ? 358  ARG B NH2   1 
ATOM   9942  N  N     . PHE D 2 359 ? 91.718  45.265  116.799 1.00 31.18  ? 359  PHE B N     1 
ATOM   9943  C  CA    . PHE D 2 359 ? 92.487  46.407  117.314 1.00 22.73  ? 359  PHE B CA    1 
ATOM   9944  C  C     . PHE D 2 359 ? 91.990  47.645  116.630 1.00 23.25  ? 359  PHE B C     1 
ATOM   9945  O  O     . PHE D 2 359 ? 91.671  47.610  115.436 1.00 29.94  ? 359  PHE B O     1 
ATOM   9946  C  CB    . PHE D 2 359 ? 94.017  46.229  117.156 1.00 18.78  ? 359  PHE B CB    1 
ATOM   9947  C  CG    . PHE D 2 359 ? 94.477  45.962  115.755 1.00 22.35  ? 359  PHE B CG    1 
ATOM   9948  C  CD1   . PHE D 2 359 ? 94.910  47.011  114.944 1.00 26.08  ? 359  PHE B CD1   1 
ATOM   9949  C  CD2   . PHE D 2 359 ? 94.529  44.659  115.260 1.00 20.39  ? 359  PHE B CD2   1 
ATOM   9950  C  CE1   . PHE D 2 359 ? 95.395  46.773  113.662 1.00 17.52  ? 359  PHE B CE1   1 
ATOM   9951  C  CE2   . PHE D 2 359 ? 95.009  44.395  113.975 1.00 27.22  ? 359  PHE B CE2   1 
ATOM   9952  C  CZ    . PHE D 2 359 ? 95.446  45.452  113.170 1.00 31.78  ? 359  PHE B CZ    1 
ATOM   9953  N  N     . ASP D 2 360 ? 91.869  48.730  117.389 1.00 22.34  ? 360  ASP B N     1 
ATOM   9954  C  CA    . ASP D 2 360 ? 91.370  49.990  116.837 1.00 22.87  ? 360  ASP B CA    1 
ATOM   9955  C  C     . ASP D 2 360 ? 92.461  51.007  116.520 1.00 32.47  ? 360  ASP B C     1 
ATOM   9956  O  O     . ASP D 2 360 ? 92.193  52.008  115.848 1.00 31.35  ? 360  ASP B O     1 
ATOM   9957  C  CB    . ASP D 2 360 ? 90.331  50.624  117.764 1.00 26.59  ? 360  ASP B CB    1 
ATOM   9958  C  CG    . ASP D 2 360 ? 89.037  49.826  117.810 1.00 38.40  ? 360  ASP B CG    1 
ATOM   9959  O  OD1   . ASP D 2 360 ? 88.691  49.156  116.810 1.00 28.85  ? 360  ASP B OD1   1 
ATOM   9960  O  OD2   . ASP D 2 360 ? 88.349  49.885  118.846 1.00 51.66  ? 360  ASP B OD2   1 
ATOM   9961  N  N     . THR D 2 361 ? 93.678  50.761  117.017 1.00 23.83  ? 361  THR B N     1 
ATOM   9962  C  CA    . THR D 2 361 ? 94.822  51.614  116.731 1.00 21.37  ? 361  THR B CA    1 
ATOM   9963  C  C     . THR D 2 361 ? 96.013  50.687  116.372 1.00 32.44  ? 361  THR B C     1 
ATOM   9964  O  O     . THR D 2 361 ? 96.049  49.522  116.773 1.00 35.44  ? 361  THR B O     1 
ATOM   9965  C  CB    . THR D 2 361 ? 95.207  52.522  117.938 1.00 27.42  ? 361  THR B CB    1 
ATOM   9966  O  OG1   . THR D 2 361 ? 95.860  51.747  118.957 1.00 36.48  ? 361  THR B OG1   1 
ATOM   9967  C  CG2   . THR D 2 361 ? 93.976  53.168  118.534 1.00 28.45  ? 361  THR B CG2   1 
ATOM   9968  N  N     . LEU D 2 362 ? 96.978  51.197  115.615 1.00 31.85  ? 362  LEU B N     1 
ATOM   9969  C  CA    . LEU D 2 362 ? 98.122  50.397  115.210 1.00 32.95  ? 362  LEU B CA    1 
ATOM   9970  C  C     . LEU D 2 362 ? 98.936  49.959  116.408 1.00 32.33  ? 362  LEU B C     1 
ATOM   9971  O  O     . LEU D 2 362 ? 99.555  48.898  116.397 1.00 36.11  ? 362  LEU B O     1 
ATOM   9972  C  CB    . LEU D 2 362 ? 98.995  51.201  114.245 1.00 25.90  ? 362  LEU B CB    1 
ATOM   9973  C  CG    . LEU D 2 362 ? 98.206  51.610  113.002 1.00 36.21  ? 362  LEU B CG    1 
ATOM   9974  C  CD1   . LEU D 2 362 ? 99.006  52.623  112.202 1.00 21.70  ? 362  LEU B CD1   1 
ATOM   9975  C  CD2   . LEU D 2 362 ? 97.864  50.361  112.158 1.00 20.17  ? 362  LEU B CD2   1 
ATOM   9976  N  N     . LYS D 2 363 ? 98.924  50.786  117.445 1.00 29.59  ? 363  LYS B N     1 
ATOM   9977  C  CA    . LYS D 2 363 ? 99.670  50.510  118.663 1.00 29.43  ? 363  LYS B CA    1 
ATOM   9978  C  C     . LYS D 2 363 ? 99.089  49.301  119.411 1.00 33.59  ? 363  LYS B C     1 
ATOM   9979  O  O     . LYS D 2 363 ? 99.835  48.525  120.040 1.00 35.58  ? 363  LYS B O     1 
ATOM   9980  C  CB    . LYS D 2 363 ? 99.666  51.766  119.545 1.00 37.40  ? 363  LYS B CB    1 
ATOM   9981  C  CG    . LYS D 2 363 ? 100.630 51.759  120.725 1.00 52.95  ? 363  LYS B CG    1 
ATOM   9982  C  CD    . LYS D 2 363 ? 100.869 53.204  121.219 1.00 61.79  ? 363  LYS B CD    1 
ATOM   9983  C  CE    . LYS D 2 363 ? 101.350 53.263  122.672 1.00 61.39  ? 363  LYS B CE    1 
ATOM   9984  N  NZ    . LYS D 2 363 ? 100.327 52.734  123.652 1.00 56.88  ? 363  LYS B NZ    1 
ATOM   9985  N  N     . GLU D 2 364 ? 97.768  49.138  119.340 1.00 27.90  ? 364  GLU B N     1 
ATOM   9986  C  CA    . GLU D 2 364 ? 97.121  48.009  120.005 1.00 37.98  ? 364  GLU B CA    1 
ATOM   9987  C  C     . GLU D 2 364 ? 97.519  46.656  119.424 1.00 29.79  ? 364  GLU B C     1 
ATOM   9988  O  O     . GLU D 2 364 ? 97.493  45.668  120.138 1.00 40.49  ? 364  GLU B O     1 
ATOM   9989  C  CB    . GLU D 2 364 ? 95.581  48.095  119.941 1.00 29.06  ? 364  GLU B CB    1 
ATOM   9990  C  CG    . GLU D 2 364 ? 94.992  49.336  120.554 1.00 37.43  ? 364  GLU B CG    1 
ATOM   9991  C  CD    . GLU D 2 364 ? 93.508  49.215  120.816 1.00 43.52  ? 364  GLU B CD    1 
ATOM   9992  O  OE1   . GLU D 2 364 ? 92.750  48.651  119.981 1.00 38.60  ? 364  GLU B OE1   1 
ATOM   9993  O  OE2   . GLU D 2 364 ? 93.104  49.700  121.888 1.00 50.85  ? 364  GLU B OE2   1 
ATOM   9994  N  N     . PHE D 2 365 ? 97.867  46.605  118.141 1.00 23.96  ? 365  PHE B N     1 
ATOM   9995  C  CA    . PHE D 2 365 ? 98.208  45.332  117.512 1.00 29.34  ? 365  PHE B CA    1 
ATOM   9996  C  C     . PHE D 2 365 ? 99.327  44.517  118.172 1.00 25.94  ? 365  PHE B C     1 
ATOM   9997  O  O     . PHE D 2 365 ? 99.145  43.339  118.453 1.00 33.14  ? 365  PHE B O     1 
ATOM   9998  C  CB    . PHE D 2 365 ? 98.539  45.532  116.043 1.00 24.23  ? 365  PHE B CB    1 
ATOM   9999  C  CG    . PHE D 2 365 ? 98.887  44.262  115.340 1.00 25.34  ? 365  PHE B CG    1 
ATOM   10000 C  CD1   . PHE D 2 365 ? 97.960  43.225  115.257 1.00 18.22  ? 365  PHE B CD1   1 
ATOM   10001 C  CD2   . PHE D 2 365 ? 100.137 44.101  114.747 1.00 20.14  ? 365  PHE B CD2   1 
ATOM   10002 C  CE1   . PHE D 2 365 ? 98.273  42.032  114.581 1.00 18.21  ? 365  PHE B CE1   1 
ATOM   10003 C  CE2   . PHE D 2 365 ? 100.462 42.911  114.063 1.00 27.66  ? 365  PHE B CE2   1 
ATOM   10004 C  CZ    . PHE D 2 365 ? 99.523  41.876  113.981 1.00 19.36  ? 365  PHE B CZ    1 
ATOM   10005 N  N     . PRO D 2 366 ? 100.496 45.133  118.419 1.00 33.02  ? 366  PRO B N     1 
ATOM   10006 C  CA    . PRO D 2 366 ? 101.582 44.381  119.055 1.00 30.76  ? 366  PRO B CA    1 
ATOM   10007 C  C     . PRO D 2 366 ? 101.231 44.034  120.515 1.00 38.00  ? 366  PRO B C     1 
ATOM   10008 O  O     . PRO D 2 366 ? 101.729 43.058  121.056 1.00 48.22  ? 366  PRO B O     1 
ATOM   10009 C  CB    . PRO D 2 366 ? 102.770 45.326  118.966 1.00 28.98  ? 366  PRO B CB    1 
ATOM   10010 C  CG    . PRO D 2 366 ? 102.342 46.392  117.973 1.00 28.68  ? 366  PRO B CG    1 
ATOM   10011 C  CD    . PRO D 2 366 ? 100.887 46.537  118.202 1.00 26.05  ? 366  PRO B CD    1 
ATOM   10012 N  N     . GLU D 2 367 ? 100.370 44.828  121.145 1.00 40.48  ? 367  GLU B N     1 
ATOM   10013 C  CA    . GLU D 2 367 ? 99.981  44.574  122.523 1.00 41.99  ? 367  GLU B CA    1 
ATOM   10014 C  C     . GLU D 2 367 ? 99.074  43.343  122.592 1.00 47.17  ? 367  GLU B C     1 
ATOM   10015 O  O     . GLU D 2 367 ? 99.362  42.366  123.299 1.00 54.69  ? 367  GLU B O     1 
ATOM   10016 C  CB    . GLU D 2 367 ? 99.257  45.793  123.102 1.00 40.78  ? 367  GLU B CB    1 
ATOM   10017 C  CG    . GLU D 2 367 ? 99.890  47.136  122.753 1.00 49.70  ? 367  GLU B CG    1 
ATOM   10018 C  CD    . GLU D 2 367 ? 99.401  48.289  123.656 1.00 64.22  ? 367  GLU B CD    1 
ATOM   10019 O  OE1   . GLU D 2 367 ? 98.294  48.168  124.243 1.00 59.95  ? 367  GLU B OE1   1 
ATOM   10020 O  OE2   . GLU D 2 367 ? 100.119 49.317  123.768 1.00 56.86  ? 367  GLU B OE2   1 
ATOM   10021 N  N     . LYS D 2 368 ? 97.992  43.383  121.824 1.00 41.62  ? 368  LYS B N     1 
ATOM   10022 C  CA    . LYS D 2 368 ? 97.019  42.307  121.796 1.00 38.07  ? 368  LYS B CA    1 
ATOM   10023 C  C     . LYS D 2 368 ? 97.468  41.017  121.080 1.00 39.22  ? 368  LYS B C     1 
ATOM   10024 O  O     . LYS D 2 368 ? 96.908  39.950  121.327 1.00 36.40  ? 368  LYS B O     1 
ATOM   10025 C  CB    . LYS D 2 368 ? 95.735  42.843  121.164 1.00 41.63  ? 368  LYS B CB    1 
ATOM   10026 C  CG    . LYS D 2 368 ? 95.287  44.155  121.764 1.00 46.62  ? 368  LYS B CG    1 
ATOM   10027 C  CD    . LYS D 2 368 ? 93.964  44.001  122.478 1.00 51.03  ? 368  LYS B CD    1 
ATOM   10028 C  CE    . LYS D 2 368 ? 92.821  44.439  121.596 1.00 46.63  ? 368  LYS B CE    1 
ATOM   10029 N  NZ    . LYS D 2 368 ? 91.512  43.841  122.014 1.00 51.85  ? 368  LYS B NZ    1 
ATOM   10030 N  N     . ALA D 2 369 ? 98.465  41.105  120.198 1.00 35.73  ? 369  ALA B N     1 
ATOM   10031 C  CA    . ALA D 2 369 ? 98.929  39.923  119.471 1.00 35.60  ? 369  ALA B CA    1 
ATOM   10032 C  C     . ALA D 2 369 ? 100.387 39.562  119.769 1.00 35.31  ? 369  ALA B C     1 
ATOM   10033 O  O     . ALA D 2 369 ? 101.043 38.884  118.978 1.00 30.28  ? 369  ALA B O     1 
ATOM   10034 C  CB    . ALA D 2 369 ? 98.749  40.147  117.978 1.00 35.80  ? 369  ALA B CB    1 
ATOM   10035 N  N     . ARG D 2 370 ? 100.877 40.005  120.917 1.00 31.71  ? 370  ARG B N     1 
ATOM   10036 C  CA    . ARG D 2 370 ? 102.258 39.777  121.311 1.00 32.38  ? 370  ARG B CA    1 
ATOM   10037 C  C     . ARG D 2 370 ? 102.670 38.306  121.175 1.00 33.63  ? 370  ARG B C     1 
ATOM   10038 O  O     . ARG D 2 370 ? 103.758 37.992  120.697 1.00 32.10  ? 370  ARG B O     1 
ATOM   10039 C  CB    . ARG D 2 370 ? 102.440 40.266  122.758 1.00 23.77  ? 370  ARG B CB    1 
ATOM   10040 C  CG    . ARG D 2 370 ? 103.862 40.541  123.123 1.00 34.68  ? 370  ARG B CG    1 
ATOM   10041 C  CD    . ARG D 2 370 ? 104.059 40.954  124.585 1.00 34.33  ? 370  ARG B CD    1 
ATOM   10042 N  NE    . ARG D 2 370 ? 105.490 40.980  124.850 1.00 25.52  ? 370  ARG B NE    1 
ATOM   10043 C  CZ    . ARG D 2 370 ? 106.307 41.907  124.365 1.00 37.98  ? 370  ARG B CZ    1 
ATOM   10044 N  NH1   . ARG D 2 370 ? 105.831 42.901  123.613 1.00 38.48  ? 370  ARG B NH1   1 
ATOM   10045 N  NH2   . ARG D 2 370 ? 107.612 41.808  124.582 1.00 45.09  ? 370  ARG B NH2   1 
ATOM   10046 N  N     . TYR D 2 371 ? 101.757 37.421  121.569 1.00 37.03  ? 371  TYR B N     1 
ATOM   10047 C  CA    . TYR D 2 371 ? 101.973 35.990  121.549 1.00 33.14  ? 371  TYR B CA    1 
ATOM   10048 C  C     . TYR D 2 371 ? 102.243 35.436  120.167 1.00 30.54  ? 371  TYR B C     1 
ATOM   10049 O  O     . TYR D 2 371 ? 102.851 34.373  120.023 1.00 28.75  ? 371  TYR B O     1 
ATOM   10050 C  CB    . TYR D 2 371 ? 100.773 35.264  122.189 1.00 36.13  ? 371  TYR B CB    1 
ATOM   10051 C  CG    . TYR D 2 371 ? 99.418  35.556  121.583 1.00 30.54  ? 371  TYR B CG    1 
ATOM   10052 C  CD1   . TYR D 2 371 ? 98.564  36.486  122.167 1.00 30.07  ? 371  TYR B CD1   1 
ATOM   10053 C  CD2   . TYR D 2 371 ? 98.954  34.835  120.470 1.00 33.26  ? 371  TYR B CD2   1 
ATOM   10054 C  CE1   . TYR D 2 371 ? 97.280  36.686  121.675 1.00 26.70  ? 371  TYR B CE1   1 
ATOM   10055 C  CE2   . TYR D 2 371 ? 97.673  35.030  119.966 1.00 24.94  ? 371  TYR B CE2   1 
ATOM   10056 C  CZ    . TYR D 2 371 ? 96.838  35.959  120.571 1.00 27.68  ? 371  TYR B CZ    1 
ATOM   10057 O  OH    . TYR D 2 371 ? 95.583  36.220  120.049 1.00 28.80  ? 371  TYR B OH    1 
ATOM   10058 N  N     . LEU D 2 372 ? 101.780 36.150  119.155 1.00 22.35  ? 372  LEU B N     1 
ATOM   10059 C  CA    . LEU D 2 372 ? 102.020 35.740  117.785 1.00 22.20  ? 372  LEU B CA    1 
ATOM   10060 C  C     . LEU D 2 372 ? 103.437 36.022  117.305 1.00 23.97  ? 372  LEU B C     1 
ATOM   10061 O  O     . LEU D 2 372 ? 103.844 35.470  116.290 1.00 32.19  ? 372  LEU B O     1 
ATOM   10062 C  CB    . LEU D 2 372 ? 101.043 36.445  116.842 1.00 22.42  ? 372  LEU B CB    1 
ATOM   10063 C  CG    . LEU D 2 372 ? 99.641  35.873  116.896 1.00 30.15  ? 372  LEU B CG    1 
ATOM   10064 C  CD1   . LEU D 2 372 ? 98.779  36.502  115.802 1.00 18.79  ? 372  LEU B CD1   1 
ATOM   10065 C  CD2   . LEU D 2 372 ? 99.753  34.352  116.716 1.00 26.26  ? 372  LEU B CD2   1 
ATOM   10066 N  N     . PHE D 2 373 ? 104.190 36.878  118.006 1.00 23.90  ? 373  PHE B N     1 
ATOM   10067 C  CA    . PHE D 2 373 ? 105.557 37.207  117.562 1.00 29.01  ? 373  PHE B CA    1 
ATOM   10068 C  C     . PHE D 2 373 ? 106.686 36.887  118.534 1.00 29.85  ? 373  PHE B C     1 
ATOM   10069 O  O     . PHE D 2 373 ? 107.863 36.954  118.178 1.00 38.46  ? 373  PHE B O     1 
ATOM   10070 C  CB    . PHE D 2 373 ? 105.652 38.689  117.221 1.00 19.30  ? 373  PHE B CB    1 
ATOM   10071 C  CG    . PHE D 2 373 ? 104.637 39.135  116.207 1.00 38.58  ? 373  PHE B CG    1 
ATOM   10072 C  CD1   . PHE D 2 373 ? 104.891 38.989  114.838 1.00 22.79  ? 373  PHE B CD1   1 
ATOM   10073 C  CD2   . PHE D 2 373 ? 103.420 39.694  116.619 1.00 18.18  ? 373  PHE B CD2   1 
ATOM   10074 C  CE1   . PHE D 2 373 ? 103.957 39.391  113.893 1.00 24.13  ? 373  PHE B CE1   1 
ATOM   10075 C  CE2   . PHE D 2 373 ? 102.481 40.098  115.677 1.00 31.05  ? 373  PHE B CE2   1 
ATOM   10076 C  CZ    . PHE D 2 373 ? 102.748 39.948  114.306 1.00 23.41  ? 373  PHE B CZ    1 
ATOM   10077 N  N     . THR D 2 374 ? 106.341 36.539  119.759 1.00 30.27  ? 374  THR B N     1 
ATOM   10078 C  CA    . THR D 2 374 ? 107.374 36.262  120.739 1.00 32.92  ? 374  THR B CA    1 
ATOM   10079 C  C     . THR D 2 374 ? 106.924 35.243  121.753 1.00 25.80  ? 374  THR B C     1 
ATOM   10080 O  O     . THR D 2 374 ? 105.743 35.008  121.918 1.00 31.16  ? 374  THR B O     1 
ATOM   10081 C  CB    . THR D 2 374 ? 107.741 37.547  121.495 1.00 41.19  ? 374  THR B CB    1 
ATOM   10082 O  OG1   . THR D 2 374 ? 108.893 37.311  122.323 1.00 37.75  ? 374  THR B OG1   1 
ATOM   10083 C  CG2   . THR D 2 374 ? 106.545 38.008  122.362 1.00 28.70  ? 374  THR B CG2   1 
ATOM   10084 N  N     . GLU D 2 375 ? 107.898 34.649  122.421 1.00 30.21  ? 375  GLU B N     1 
ATOM   10085 C  CA    . GLU D 2 375 ? 107.675 33.672  123.474 1.00 28.24  ? 375  GLU B CA    1 
ATOM   10086 C  C     . GLU D 2 375 ? 107.486 34.468  124.780 1.00 29.75  ? 375  GLU B C     1 
ATOM   10087 O  O     . GLU D 2 375 ? 107.046 33.937  125.792 1.00 29.52  ? 375  GLU B O     1 
ATOM   10088 C  CB    . GLU D 2 375 ? 108.909 32.773  123.586 1.00 31.04  ? 375  GLU B CB    1 
ATOM   10089 C  CG    . GLU D 2 375 ? 108.692 31.319  123.192 1.00 40.28  ? 375  GLU B CG    1 
ATOM   10090 C  CD    . GLU D 2 375 ? 107.634 31.149  122.133 1.00 40.18  ? 375  GLU B CD    1 
ATOM   10091 O  OE1   . GLU D 2 375 ? 106.544 30.664  122.468 1.00 48.23  ? 375  GLU B OE1   1 
ATOM   10092 O  OE2   . GLU D 2 375 ? 107.881 31.509  120.969 1.00 54.24  ? 375  GLU B OE2   1 
ATOM   10093 N  N     . ASP D 2 376 ? 107.804 35.759  124.724 1.00 30.33  ? 376  ASP B N     1 
ATOM   10094 C  CA    . ASP D 2 376 ? 107.716 36.683  125.861 1.00 35.56  ? 376  ASP B CA    1 
ATOM   10095 C  C     . ASP D 2 376 ? 106.350 37.386  125.963 1.00 40.15  ? 376  ASP B C     1 
ATOM   10096 O  O     . ASP D 2 376 ? 106.242 38.611  125.753 1.00 30.08  ? 376  ASP B O     1 
ATOM   10097 C  CB    . ASP D 2 376 ? 108.807 37.747  125.736 1.00 29.24  ? 376  ASP B CB    1 
ATOM   10098 C  CG    . ASP D 2 376 ? 108.873 38.647  126.943 1.00 45.28  ? 376  ASP B CG    1 
ATOM   10099 O  OD1   . ASP D 2 376 ? 109.571 39.687  126.908 1.00 50.86  ? 376  ASP B OD1   1 
ATOM   10100 O  OD2   . ASP D 2 376 ? 108.227 38.297  127.945 1.00 45.85  ? 376  ASP B OD2   1 
ATOM   10101 N  N     . TYR D 2 377 ? 105.319 36.614  126.306 1.00 34.85  ? 377  TYR B N     1 
ATOM   10102 C  CA    . TYR D 2 377 ? 103.967 37.148  126.405 1.00 37.88  ? 377  TYR B CA    1 
ATOM   10103 C  C     . TYR D 2 377 ? 103.347 36.855  127.773 1.00 38.23  ? 377  TYR B C     1 
ATOM   10104 O  O     . TYR D 2 377 ? 103.734 35.914  128.435 1.00 33.51  ? 377  TYR B O     1 
ATOM   10105 C  CB    . TYR D 2 377 ? 103.091 36.571  125.267 1.00 30.27  ? 377  TYR B CB    1 
ATOM   10106 C  CG    . TYR D 2 377 ? 103.049 35.070  125.203 1.00 32.86  ? 377  TYR B CG    1 
ATOM   10107 C  CD1   . TYR D 2 377 ? 103.989 34.354  124.451 1.00 34.32  ? 377  TYR B CD1   1 
ATOM   10108 C  CD2   . TYR D 2 377 ? 102.105 34.348  125.938 1.00 25.79  ? 377  TYR B CD2   1 
ATOM   10109 C  CE1   . TYR D 2 377 ? 103.992 32.938  124.442 1.00 31.05  ? 377  TYR B CE1   1 
ATOM   10110 C  CE2   . TYR D 2 377 ? 102.097 32.932  125.933 1.00 23.44  ? 377  TYR B CE2   1 
ATOM   10111 C  CZ    . TYR D 2 377 ? 103.040 32.234  125.190 1.00 32.65  ? 377  TYR B CZ    1 
ATOM   10112 O  OH    . TYR D 2 377 ? 103.059 30.840  125.221 1.00 35.91  ? 377  TYR B OH    1 
ATOM   10113 N  N     . PRO D 2 378 ? 102.353 37.654  128.200 1.00 40.17  ? 378  PRO B N     1 
ATOM   10114 C  CA    . PRO D 2 378 ? 101.726 37.438  129.502 1.00 37.60  ? 378  PRO B CA    1 
ATOM   10115 C  C     . PRO D 2 378 ? 100.625 36.395  129.499 1.00 39.37  ? 378  PRO B C     1 
ATOM   10116 O  O     . PRO D 2 378 ? 100.013 36.109  128.473 1.00 42.13  ? 378  PRO B O     1 
ATOM   10117 C  CB    . PRO D 2 378 ? 101.199 38.820  129.847 1.00 36.05  ? 378  PRO B CB    1 
ATOM   10118 C  CG    . PRO D 2 378 ? 100.692 39.271  128.533 1.00 33.96  ? 378  PRO B CG    1 
ATOM   10119 C  CD    . PRO D 2 378 ? 101.792 38.852  127.553 1.00 34.28  ? 378  PRO B CD    1 
ATOM   10120 N  N     . VAL D 2 379 ? 100.392 35.816  130.670 1.00 41.41  ? 379  VAL B N     1 
ATOM   10121 C  CA    . VAL D 2 379 ? 99.352  34.814  130.842 1.00 38.84  ? 379  VAL B CA    1 
ATOM   10122 C  C     . VAL D 2 379 ? 98.374  35.396  131.833 1.00 39.54  ? 379  VAL B C     1 
ATOM   10123 O  O     . VAL D 2 379 ? 98.758  35.731  132.955 1.00 45.78  ? 379  VAL B O     1 
ATOM   10124 C  CB    . VAL D 2 379 ? 99.902  33.517  131.439 1.00 41.18  ? 379  VAL B CB    1 
ATOM   10125 C  CG1   . VAL D 2 379 ? 98.771  32.484  131.571 1.00 28.95  ? 379  VAL B CG1   1 
ATOM   10126 C  CG2   . VAL D 2 379 ? 101.047 32.995  130.579 1.00 30.61  ? 379  VAL B CG2   1 
ATOM   10127 N  N     . SER D 2 380 ? 97.118  35.526  131.427 1.00 34.35  ? 380  SER B N     1 
ATOM   10128 C  CA    . SER D 2 380 ? 96.116  36.083  132.318 1.00 40.66  ? 380  SER B CA    1 
ATOM   10129 C  C     . SER D 2 380 ? 95.738  35.062  133.379 1.00 43.55  ? 380  SER B C     1 
ATOM   10130 O  O     . SER D 2 380 ? 95.902  33.856  133.187 1.00 43.88  ? 380  SER B O     1 
ATOM   10131 C  CB    . SER D 2 380 ? 94.863  36.510  131.530 1.00 24.65  ? 380  SER B CB    1 
ATOM   10132 O  OG    . SER D 2 380 ? 94.186  35.392  131.002 1.00 34.34  ? 380  SER B OG    1 
ATOM   10133 N  N     . GLU D 2 381 ? 95.237  35.556  134.502 1.00 50.95  ? 381  GLU B N     1 
ATOM   10134 C  CA    . GLU D 2 381 ? 94.813  34.694  135.587 1.00 48.84  ? 381  GLU B CA    1 
ATOM   10135 C  C     . GLU D 2 381 ? 93.760  33.747  135.039 1.00 46.97  ? 381  GLU B C     1 
ATOM   10136 O  O     . GLU D 2 381 ? 93.891  32.526  135.139 1.00 45.15  ? 381  GLU B O     1 
ATOM   10137 C  CB    . GLU D 2 381 ? 94.205  35.533  136.704 1.00 64.65  ? 381  GLU B CB    1 
ATOM   10138 C  CG    . GLU D 2 381 ? 93.682  34.716  137.877 1.00 80.81  ? 381  GLU B CG    1 
ATOM   10139 C  CD    . GLU D 2 381 ? 92.320  35.200  138.356 1.00 91.97  ? 381  GLU B CD    1 
ATOM   10140 O  OE1   . GLU D 2 381 ? 92.164  36.424  138.582 1.00 93.76  ? 381  GLU B OE1   1 
ATOM   10141 O  OE2   . GLU D 2 381 ? 91.409  34.350  138.509 1.00 96.75  ? 381  GLU B OE2   1 
ATOM   10142 N  N     . LYS D 2 382 ? 92.718  34.320  134.445 1.00 43.52  ? 382  LYS B N     1 
ATOM   10143 C  CA    . LYS D 2 382 ? 91.626  33.531  133.889 1.00 43.93  ? 382  LYS B CA    1 
ATOM   10144 C  C     . LYS D 2 382 ? 92.139  32.481  132.893 1.00 38.14  ? 382  LYS B C     1 
ATOM   10145 O  O     . LYS D 2 382 ? 91.621  31.373  132.856 1.00 39.14  ? 382  LYS B O     1 
ATOM   10146 C  CB    . LYS D 2 382 ? 90.608  34.448  133.195 1.00 40.67  ? 382  LYS B CB    1 
ATOM   10147 C  CG    . LYS D 2 382 ? 90.307  35.718  133.955 1.00 56.14  ? 382  LYS B CG    1 
ATOM   10148 C  CD    . LYS D 2 382 ? 89.035  35.607  134.787 1.00 70.78  ? 382  LYS B CD    1 
ATOM   10149 C  CE    . LYS D 2 382 ? 87.789  36.031  133.998 1.00 75.89  ? 382  LYS B CE    1 
ATOM   10150 N  NZ    . LYS D 2 382 ? 87.446  35.116  132.867 1.00 79.03  ? 382  LYS B NZ    1 
ATOM   10151 N  N     . ALA D 2 383 ? 93.135  32.828  132.075 1.00 35.95  ? 383  ALA B N     1 
ATOM   10152 C  CA    . ALA D 2 383 ? 93.668  31.865  131.106 1.00 39.38  ? 383  ALA B CA    1 
ATOM   10153 C  C     . ALA D 2 383 ? 94.398  30.754  131.868 1.00 38.25  ? 383  ALA B C     1 
ATOM   10154 O  O     . ALA D 2 383 ? 94.228  29.572  131.569 1.00 35.36  ? 383  ALA B O     1 
ATOM   10155 C  CB    . ALA D 2 383 ? 94.605  32.549  130.139 1.00 28.65  ? 383  ALA B CB    1 
ATOM   10156 N  N     . GLN D 2 384 ? 95.197  31.152  132.858 1.00 39.00  ? 384  GLN B N     1 
ATOM   10157 C  CA    . GLN D 2 384 ? 95.935  30.223  133.721 1.00 37.28  ? 384  GLN B CA    1 
ATOM   10158 C  C     . GLN D 2 384 ? 94.974  29.198  134.355 1.00 39.94  ? 384  GLN B C     1 
ATOM   10159 O  O     . GLN D 2 384 ? 95.238  28.004  134.353 1.00 49.83  ? 384  GLN B O     1 
ATOM   10160 C  CB    . GLN D 2 384 ? 96.652  31.012  134.824 1.00 33.32  ? 384  GLN B CB    1 
ATOM   10161 C  CG    . GLN D 2 384 ? 97.526  30.174  135.734 1.00 49.92  ? 384  GLN B CG    1 
ATOM   10162 C  CD    . GLN D 2 384 ? 98.581  29.392  134.967 1.00 61.61  ? 384  GLN B CD    1 
ATOM   10163 O  OE1   . GLN D 2 384 ? 99.567  29.958  134.479 1.00 59.52  ? 384  GLN B OE1   1 
ATOM   10164 N  NE2   . GLN D 2 384 ? 98.367  28.082  134.844 1.00 61.12  ? 384  GLN B NE2   1 
ATOM   10165 N  N     . ARG D 2 385 ? 93.852  29.667  134.885 1.00 42.63  ? 385  ARG B N     1 
ATOM   10166 C  CA    . ARG D 2 385 ? 92.876  28.788  135.514 1.00 40.89  ? 385  ARG B CA    1 
ATOM   10167 C  C     . ARG D 2 385 ? 92.216  27.857  134.537 1.00 44.61  ? 385  ARG B C     1 
ATOM   10168 O  O     . ARG D 2 385 ? 91.906  26.721  134.890 1.00 56.74  ? 385  ARG B O     1 
ATOM   10169 C  CB    . ARG D 2 385 ? 91.773  29.587  136.208 1.00 44.01  ? 385  ARG B CB    1 
ATOM   10170 C  CG    . ARG D 2 385 ? 92.010  29.908  137.668 1.00 56.79  ? 385  ARG B CG    1 
ATOM   10171 C  CD    . ARG D 2 385 ? 90.832  30.716  138.189 1.00 70.84  ? 385  ARG B CD    1 
ATOM   10172 N  NE    . ARG D 2 385 ? 89.553  30.091  137.830 1.00 76.37  ? 385  ARG B NE    1 
ATOM   10173 C  CZ    . ARG D 2 385 ? 88.505  30.749  137.335 1.00 74.78  ? 385  ARG B CZ    1 
ATOM   10174 N  NH1   . ARG D 2 385 ? 88.571  32.062  137.133 1.00 57.87  ? 385  ARG B NH1   1 
ATOM   10175 N  NH2   . ARG D 2 385 ? 87.388  30.092  137.037 1.00 81.13  ? 385  ARG B NH2   1 
ATOM   10176 N  N     . LYS D 2 386 ? 91.973  28.327  133.316 1.00 42.35  ? 386  LYS B N     1 
ATOM   10177 C  CA    . LYS D 2 386 ? 91.319  27.487  132.315 1.00 37.39  ? 386  LYS B CA    1 
ATOM   10178 C  C     . LYS D 2 386 ? 92.268  26.386  131.896 1.00 35.81  ? 386  LYS B C     1 
ATOM   10179 O  O     . LYS D 2 386 ? 91.865  25.267  131.562 1.00 34.54  ? 386  LYS B O     1 
ATOM   10180 C  CB    . LYS D 2 386 ? 90.944  28.305  131.083 1.00 32.76  ? 386  LYS B CB    1 
ATOM   10181 C  CG    . LYS D 2 386 ? 89.879  27.644  130.240 1.00 40.54  ? 386  LYS B CG    1 
ATOM   10182 C  CD    . LYS D 2 386 ? 88.684  27.305  131.129 1.00 50.95  ? 386  LYS B CD    1 
ATOM   10183 C  CE    . LYS D 2 386 ? 87.364  27.344  130.384 1.00 46.93  ? 386  LYS B CE    1 
ATOM   10184 N  NZ    . LYS D 2 386 ? 87.077  28.714  129.891 1.00 53.77  ? 386  LYS B NZ    1 
ATOM   10185 N  N     . LEU D 2 387 ? 93.544  26.725  131.906 1.00 36.10  ? 387  LEU B N     1 
ATOM   10186 C  CA    . LEU D 2 387 ? 94.577  25.778  131.537 1.00 50.70  ? 387  LEU B CA    1 
ATOM   10187 C  C     . LEU D 2 387 ? 94.674  24.668  132.597 1.00 50.94  ? 387  LEU B C     1 
ATOM   10188 O  O     . LEU D 2 387 ? 94.697  23.481  132.266 1.00 50.28  ? 387  LEU B O     1 
ATOM   10189 C  CB    . LEU D 2 387 ? 95.910  26.518  131.383 1.00 41.07  ? 387  LEU B CB    1 
ATOM   10190 C  CG    . LEU D 2 387 ? 97.130  25.726  130.929 1.00 49.74  ? 387  LEU B CG    1 
ATOM   10191 C  CD1   . LEU D 2 387 ? 96.819  24.888  129.686 1.00 43.03  ? 387  LEU B CD1   1 
ATOM   10192 C  CD2   . LEU D 2 387 ? 98.246  26.722  130.663 1.00 37.00  ? 387  LEU B CD2   1 
ATOM   10193 N  N     . GLU D 2 388 ? 94.708  25.055  133.870 1.00 54.85  ? 388  GLU B N     1 
ATOM   10194 C  CA    . GLU D 2 388 ? 94.801  24.084  134.963 1.00 54.76  ? 388  GLU B CA    1 
ATOM   10195 C  C     . GLU D 2 388 ? 93.587  23.159  134.942 1.00 55.26  ? 388  GLU B C     1 
ATOM   10196 O  O     . GLU D 2 388 ? 93.697  21.941  135.073 1.00 59.06  ? 388  GLU B O     1 
ATOM   10197 C  CB    . GLU D 2 388 ? 94.890  24.822  136.298 1.00 51.88  ? 388  GLU B CB    1 
ATOM   10198 C  CG    . GLU D 2 388 ? 96.151  25.667  136.409 1.00 72.28  ? 388  GLU B CG    1 
ATOM   10199 C  CD    . GLU D 2 388 ? 96.034  26.811  137.407 1.00 88.01  ? 388  GLU B CD    1 
ATOM   10200 O  OE1   . GLU D 2 388 ? 97.026  27.561  137.559 1.00 89.05  ? 388  GLU B OE1   1 
ATOM   10201 O  OE2   . GLU D 2 388 ? 94.956  26.968  138.031 1.00 95.67  ? 388  GLU B OE2   1 
ATOM   10202 N  N     . GLU D 2 389 ? 92.423  23.743  134.748 1.00 47.29  ? 389  GLU B N     1 
ATOM   10203 C  CA    . GLU D 2 389 ? 91.195  22.970  134.712 1.00 53.16  ? 389  GLU B CA    1 
ATOM   10204 C  C     . GLU D 2 389 ? 91.179  21.965  133.555 1.00 51.51  ? 389  GLU B C     1 
ATOM   10205 O  O     . GLU D 2 389 ? 90.629  20.870  133.687 1.00 51.47  ? 389  GLU B O     1 
ATOM   10206 C  CB    . GLU D 2 389 ? 90.014  23.937  134.587 1.00 58.19  ? 389  GLU B CB    1 
ATOM   10207 C  CG    . GLU D 2 389 ? 88.679  23.383  134.963 1.00 63.05  ? 389  GLU B CG    1 
ATOM   10208 C  CD    . GLU D 2 389 ? 87.585  24.424  134.838 1.00 69.08  ? 389  GLU B CD    1 
ATOM   10209 O  OE1   . GLU D 2 389 ? 86.508  24.230  135.442 1.00 80.94  ? 389  GLU B OE1   1 
ATOM   10210 O  OE2   . GLU D 2 389 ? 87.795  25.431  134.130 1.00 62.12  ? 389  GLU B OE2   1 
ATOM   10211 N  N     . GLY D 2 390 ? 91.775  22.333  132.423 1.00 46.41  ? 390  GLY B N     1 
ATOM   10212 C  CA    . GLY D 2 390 ? 91.776  21.434  131.273 1.00 46.27  ? 390  GLY B CA    1 
ATOM   10213 C  C     . GLY D 2 390 ? 93.026  20.592  131.018 1.00 50.73  ? 390  GLY B C     1 
ATOM   10214 O  O     . GLY D 2 390 ? 93.113  19.879  130.003 1.00 46.85  ? 390  GLY B O     1 
ATOM   10215 N  N     . LEU D 2 391 ? 93.982  20.661  131.941 1.00 46.97  ? 391  LEU B N     1 
ATOM   10216 C  CA    . LEU D 2 391 ? 95.228  19.920  131.818 1.00 50.85  ? 391  LEU B CA    1 
ATOM   10217 C  C     . LEU D 2 391 ? 95.051  18.447  131.495 1.00 50.87  ? 391  LEU B C     1 
ATOM   10218 O  O     . LEU D 2 391 ? 95.757  17.925  130.636 1.00 57.58  ? 391  LEU B O     1 
ATOM   10219 C  CB    . LEU D 2 391 ? 96.063  20.069  133.085 1.00 43.67  ? 391  LEU B CB    1 
ATOM   10220 C  CG    . LEU D 2 391 ? 97.479  20.592  132.830 1.00 55.00  ? 391  LEU B CG    1 
ATOM   10221 C  CD1   . LEU D 2 391 ? 97.436  21.822  131.958 1.00 44.21  ? 391  LEU B CD1   1 
ATOM   10222 C  CD2   . LEU D 2 391 ? 98.152  20.909  134.159 1.00 55.60  ? 391  LEU B CD2   1 
ATOM   10223 N  N     . PRO D 2 392 ? 94.105  17.751  132.162 1.00 52.94  ? 392  PRO B N     1 
ATOM   10224 C  CA    . PRO D 2 392 ? 93.959  16.331  131.830 1.00 46.74  ? 392  PRO B CA    1 
ATOM   10225 C  C     . PRO D 2 392 ? 93.450  16.094  130.417 1.00 42.50  ? 392  PRO B C     1 
ATOM   10226 O  O     . PRO D 2 392 ? 93.898  15.164  129.750 1.00 48.26  ? 392  PRO B O     1 
ATOM   10227 C  CB    . PRO D 2 392 ? 93.027  15.795  132.930 1.00 43.48  ? 392  PRO B CB    1 
ATOM   10228 C  CG    . PRO D 2 392 ? 92.234  16.980  133.314 1.00 53.79  ? 392  PRO B CG    1 
ATOM   10229 C  CD    . PRO D 2 392 ? 93.246  18.108  133.303 1.00 49.91  ? 392  PRO B CD    1 
ATOM   10230 N  N     . LEU D 2 393 ? 92.514  16.904  129.937 1.00 38.23  ? 393  LEU B N     1 
ATOM   10231 C  CA    . LEU D 2 393 ? 92.076  16.703  128.550 1.00 41.35  ? 393  LEU B CA    1 
ATOM   10232 C  C     . LEU D 2 393 ? 93.256  17.019  127.616 1.00 37.53  ? 393  LEU B C     1 
ATOM   10233 O  O     . LEU D 2 393 ? 93.476  16.316  126.637 1.00 41.89  ? 393  LEU B O     1 
ATOM   10234 C  CB    . LEU D 2 393 ? 90.909  17.628  128.180 1.00 41.60  ? 393  LEU B CB    1 
ATOM   10235 C  CG    . LEU D 2 393 ? 89.488  17.100  128.344 1.00 46.81  ? 393  LEU B CG    1 
ATOM   10236 C  CD1   . LEU D 2 393 ? 88.499  18.189  127.953 1.00 43.44  ? 393  LEU B CD1   1 
ATOM   10237 C  CD2   . LEU D 2 393 ? 89.294  15.867  127.471 1.00 46.88  ? 393  LEU B CD2   1 
ATOM   10238 N  N     . LEU D 2 394 ? 94.001  18.086  127.916 1.00 28.05  ? 394  LEU B N     1 
ATOM   10239 C  CA    . LEU D 2 394 ? 95.131  18.458  127.080 1.00 37.03  ? 394  LEU B CA    1 
ATOM   10240 C  C     . LEU D 2 394 ? 96.180  17.363  126.995 1.00 38.86  ? 394  LEU B C     1 
ATOM   10241 O  O     . LEU D 2 394 ? 96.674  17.055  125.904 1.00 32.14  ? 394  LEU B O     1 
ATOM   10242 C  CB    . LEU D 2 394 ? 95.777  19.768  127.558 1.00 34.03  ? 394  LEU B CB    1 
ATOM   10243 C  CG    . LEU D 2 394 ? 94.900  20.997  127.249 1.00 40.60  ? 394  LEU B CG    1 
ATOM   10244 C  CD1   . LEU D 2 394 ? 95.681  22.270  127.470 1.00 27.08  ? 394  LEU B CD1   1 
ATOM   10245 C  CD2   . LEU D 2 394 ? 94.407  20.932  125.801 1.00 36.44  ? 394  LEU B CD2   1 
ATOM   10246 N  N     . LYS D 2 395 ? 96.517  16.761  128.128 1.00 35.16  ? 395  LYS B N     1 
ATOM   10247 C  CA    . LYS D 2 395 ? 97.519  15.698  128.111 1.00 40.28  ? 395  LYS B CA    1 
ATOM   10248 C  C     . LYS D 2 395 ? 97.062  14.531  127.251 1.00 39.70  ? 395  LYS B C     1 
ATOM   10249 O  O     . LYS D 2 395 ? 97.891  13.840  126.661 1.00 37.66  ? 395  LYS B O     1 
ATOM   10250 C  CB    . LYS D 2 395 ? 97.851  15.241  129.536 1.00 42.14  ? 395  LYS B CB    1 
ATOM   10251 C  CG    . LYS D 2 395 ? 98.390  16.397  130.380 1.00 39.53  ? 395  LYS B CG    1 
ATOM   10252 C  CD    . LYS D 2 395 ? 99.033  15.982  131.695 1.00 56.16  ? 395  LYS B CD    1 
ATOM   10253 C  CE    . LYS D 2 395 ? 99.595  17.219  132.406 1.00 57.73  ? 395  LYS B CE    1 
ATOM   10254 N  NZ    . LYS D 2 395 ? 100.417 16.887  133.604 1.00 71.26  ? 395  LYS B NZ    1 
ATOM   10255 N  N     . GLU D 2 396 ? 95.749  14.331  127.143 1.00 30.74  ? 396  GLU B N     1 
ATOM   10256 C  CA    . GLU D 2 396 ? 95.243  13.259  126.309 1.00 34.27  ? 396  GLU B CA    1 
ATOM   10257 C  C     . GLU D 2 396 ? 95.140  13.726  124.872 1.00 36.24  ? 396  GLU B C     1 
ATOM   10258 O  O     . GLU D 2 396 ? 95.055  12.925  123.939 1.00 43.59  ? 396  GLU B O     1 
ATOM   10259 C  CB    . GLU D 2 396 ? 93.861  12.813  126.749 1.00 34.94  ? 396  GLU B CB    1 
ATOM   10260 C  CG    . GLU D 2 396 ? 93.812  12.052  128.033 1.00 56.32  ? 396  GLU B CG    1 
ATOM   10261 C  CD    . GLU D 2 396 ? 92.396  11.616  128.322 1.00 74.71  ? 396  GLU B CD    1 
ATOM   10262 O  OE1   . GLU D 2 396 ? 91.845  10.852  127.490 1.00 76.91  ? 396  GLU B OE1   1 
ATOM   10263 O  OE2   . GLU D 2 396 ? 91.832  12.051  129.359 1.00 78.39  ? 396  GLU B OE2   1 
ATOM   10264 N  N     . LEU D 2 397 ? 95.113  15.027  124.674 1.00 33.17  ? 397  LEU B N     1 
ATOM   10265 C  CA    . LEU D 2 397 ? 95.023  15.516  123.315 1.00 37.04  ? 397  LEU B CA    1 
ATOM   10266 C  C     . LEU D 2 397 ? 96.418  15.506  122.692 1.00 33.90  ? 397  LEU B C     1 
ATOM   10267 O  O     . LEU D 2 397 ? 96.594  15.175  121.515 1.00 40.68  ? 397  LEU B O     1 
ATOM   10268 C  CB    . LEU D 2 397 ? 94.462  16.944  123.304 1.00 35.89  ? 397  LEU B CB    1 
ATOM   10269 C  CG    . LEU D 2 397 ? 94.298  17.598  121.923 1.00 39.31  ? 397  LEU B CG    1 
ATOM   10270 C  CD1   . LEU D 2 397 ? 93.297  16.774  121.079 1.00 32.50  ? 397  LEU B CD1   1 
ATOM   10271 C  CD2   . LEU D 2 397 ? 93.836  19.061  122.082 1.00 27.68  ? 397  LEU B CD2   1 
ATOM   10272 N  N     . TYR D 2 398 ? 97.412  15.840  123.503 1.00 27.87  ? 398  TYR B N     1 
ATOM   10273 C  CA    . TYR D 2 398 ? 98.776  15.936  123.020 1.00 35.65  ? 398  TYR B CA    1 
ATOM   10274 C  C     . TYR D 2 398 ? 99.243  14.840  122.083 1.00 38.64  ? 398  TYR B C     1 
ATOM   10275 O  O     . TYR D 2 398 ? 99.731  15.133  121.003 1.00 43.55  ? 398  TYR B O     1 
ATOM   10276 C  CB    . TYR D 2 398 ? 99.761  16.082  124.176 1.00 32.16  ? 398  TYR B CB    1 
ATOM   10277 C  CG    . TYR D 2 398 ? 101.177 16.228  123.690 1.00 30.25  ? 398  TYR B CG    1 
ATOM   10278 C  CD1   . TYR D 2 398 ? 101.696 17.471  123.298 1.00 31.91  ? 398  TYR B CD1   1 
ATOM   10279 C  CD2   . TYR D 2 398 ? 101.991 15.116  123.577 1.00 31.22  ? 398  TYR B CD2   1 
ATOM   10280 C  CE1   . TYR D 2 398 ? 103.008 17.586  122.803 1.00 21.94  ? 398  TYR B CE1   1 
ATOM   10281 C  CE2   . TYR D 2 398 ? 103.286 15.213  123.094 1.00 32.59  ? 398  TYR B CE2   1 
ATOM   10282 C  CZ    . TYR D 2 398 ? 103.792 16.440  122.715 1.00 29.33  ? 398  TYR B CZ    1 
ATOM   10283 O  OH    . TYR D 2 398 ? 105.105 16.472  122.326 1.00 31.80  ? 398  TYR B OH    1 
ATOM   10284 N  N     . PRO D 2 399 ? 99.106  13.568  122.473 1.00 39.76  ? 399  PRO B N     1 
ATOM   10285 C  CA    . PRO D 2 399 ? 99.560  12.517  121.555 1.00 45.25  ? 399  PRO B CA    1 
ATOM   10286 C  C     . PRO D 2 399 ? 98.845  12.583  120.210 1.00 45.76  ? 399  PRO B C     1 
ATOM   10287 O  O     . PRO D 2 399 ? 99.450  12.313  119.175 1.00 54.28  ? 399  PRO B O     1 
ATOM   10288 C  CB    . PRO D 2 399 ? 99.239  11.214  122.299 1.00 43.96  ? 399  PRO B CB    1 
ATOM   10289 C  CG    . PRO D 2 399 ? 99.273  11.616  123.732 1.00 45.87  ? 399  PRO B CG    1 
ATOM   10290 C  CD    . PRO D 2 399 ? 98.630  12.998  123.742 1.00 46.60  ? 399  PRO B CD    1 
ATOM   10291 N  N     . ARG D 2 400 ? 97.565  12.941  120.201 1.00 41.11  ? 400  ARG B N     1 
ATOM   10292 C  CA    . ARG D 2 400 ? 96.869  12.987  118.920 1.00 41.29  ? 400  ARG B CA    1 
ATOM   10293 C  C     . ARG D 2 400 ? 97.430  14.089  118.034 1.00 41.71  ? 400  ARG B C     1 
ATOM   10294 O  O     . ARG D 2 400 ? 97.508  13.952  116.807 1.00 37.38  ? 400  ARG B O     1 
ATOM   10295 C  CB    . ARG D 2 400 ? 95.356  13.186  119.098 1.00 47.84  ? 400  ARG B CB    1 
ATOM   10296 C  CG    . ARG D 2 400 ? 94.561  11.902  119.386 1.00 54.41  ? 400  ARG B CG    1 
ATOM   10297 C  CD    . ARG D 2 400 ? 94.498  11.632  120.886 1.00 64.90  ? 400  ARG B CD    1 
ATOM   10298 N  NE    . ARG D 2 400 ? 93.552  10.589  121.307 1.00 59.90  ? 400  ARG B NE    1 
ATOM   10299 C  CZ    . ARG D 2 400 ? 92.335  10.412  120.804 1.00 55.15  ? 400  ARG B CZ    1 
ATOM   10300 N  NH1   . ARG D 2 400 ? 91.877  11.186  119.829 1.00 61.10  ? 400  ARG B NH1   1 
ATOM   10301 N  NH2   . ARG D 2 400 ? 91.547  9.489   121.324 1.00 57.04  ? 400  ARG B NH2   1 
ATOM   10302 N  N     . LEU D 2 401 ? 97.822  15.193  118.646 1.00 29.29  ? 401  LEU B N     1 
ATOM   10303 C  CA    . LEU D 2 401 ? 98.375  16.266  117.862 1.00 29.34  ? 401  LEU B CA    1 
ATOM   10304 C  C     . LEU D 2 401 ? 99.775  15.891  117.422 1.00 35.37  ? 401  LEU B C     1 
ATOM   10305 O  O     . LEU D 2 401 ? 100.199 16.271  116.349 1.00 36.16  ? 401  LEU B O     1 
ATOM   10306 C  CB    . LEU D 2 401 ? 98.455  17.541  118.677 1.00 34.56  ? 401  LEU B CB    1 
ATOM   10307 C  CG    . LEU D 2 401 ? 97.163  18.309  118.893 1.00 38.69  ? 401  LEU B CG    1 
ATOM   10308 C  CD1   . LEU D 2 401 ? 97.403  19.348  119.971 1.00 34.84  ? 401  LEU B CD1   1 
ATOM   10309 C  CD2   . LEU D 2 401 ? 96.708  18.955  117.574 1.00 37.33  ? 401  LEU B CD2   1 
ATOM   10310 N  N     . ARG D 2 402 ? 100.497 15.145  118.249 1.00 27.32  ? 402  ARG B N     1 
ATOM   10311 C  CA    . ARG D 2 402 ? 101.852 14.781  117.905 1.00 31.60  ? 402  ARG B CA    1 
ATOM   10312 C  C     . ARG D 2 402 ? 101.896 13.884  116.683 1.00 35.58  ? 402  ARG B C     1 
ATOM   10313 O  O     . ARG D 2 402 ? 102.855 13.903  115.938 1.00 39.11  ? 402  ARG B O     1 
ATOM   10314 C  CB    . ARG D 2 402 ? 102.548 14.096  119.084 1.00 42.40  ? 402  ARG B CB    1 
ATOM   10315 C  CG    . ARG D 2 402 ? 103.971 13.679  118.756 1.00 54.86  ? 402  ARG B CG    1 
ATOM   10316 C  CD    . ARG D 2 402 ? 104.614 12.856  119.870 1.00 70.18  ? 402  ARG B CD    1 
ATOM   10317 N  NE    . ARG D 2 402 ? 105.582 13.634  120.640 1.00 82.91  ? 402  ARG B NE    1 
ATOM   10318 C  CZ    . ARG D 2 402 ? 106.673 14.192  120.121 1.00 85.63  ? 402  ARG B CZ    1 
ATOM   10319 N  NH1   . ARG D 2 402 ? 106.930 14.053  118.823 1.00 89.35  ? 402  ARG B NH1   1 
ATOM   10320 N  NH2   . ARG D 2 402 ? 107.506 14.885  120.896 1.00 86.84  ? 402  ARG B NH2   1 
ATOM   10321 N  N     . ALA D 2 403 ? 100.841 13.122  116.457 1.00 34.41  ? 403  ALA B N     1 
ATOM   10322 C  CA    . ALA D 2 403 ? 100.802 12.243  115.306 1.00 33.39  ? 403  ALA B CA    1 
ATOM   10323 C  C     . ALA D 2 403 ? 100.028 12.797  114.118 1.00 36.47  ? 403  ALA B C     1 
ATOM   10324 O  O     . ALA D 2 403 ? 99.958  12.134  113.087 1.00 46.94  ? 403  ALA B O     1 
ATOM   10325 C  CB    . ALA D 2 403 ? 100.215 10.912  115.706 1.00 31.22  ? 403  ALA B CB    1 
ATOM   10326 N  N     . GLN D 2 404 ? 99.428  13.980  114.249 1.00 33.95  ? 404  GLN B N     1 
ATOM   10327 C  CA    . GLN D 2 404 ? 98.671  14.570  113.134 1.00 35.85  ? 404  GLN B CA    1 
ATOM   10328 C  C     . GLN D 2 404 ? 99.630  14.945  112.005 1.00 39.87  ? 404  GLN B C     1 
ATOM   10329 O  O     . GLN D 2 404 ? 100.529 15.778  112.179 1.00 42.96  ? 404  GLN B O     1 
ATOM   10330 C  CB    . GLN D 2 404 ? 97.912  15.819  113.604 1.00 33.95  ? 404  GLN B CB    1 
ATOM   10331 C  CG    . GLN D 2 404 ? 97.127  16.510  112.504 1.00 38.25  ? 404  GLN B CG    1 
ATOM   10332 C  CD    . GLN D 2 404 ? 96.024  15.637  111.918 1.00 26.88  ? 404  GLN B CD    1 
ATOM   10333 O  OE1   . GLN D 2 404 ? 95.424  15.967  110.893 1.00 38.03  ? 404  GLN B OE1   1 
ATOM   10334 N  NE2   . GLN D 2 404 ? 95.750  14.532  112.570 1.00 30.41  ? 404  GLN B NE2   1 
ATOM   10335 N  N     . GLU D 2 405 ? 99.449  14.336  110.845 1.00 42.13  ? 405  GLU B N     1 
ATOM   10336 C  CA    . GLU D 2 405 ? 100.327 14.620  109.717 1.00 44.50  ? 405  GLU B CA    1 
ATOM   10337 C  C     . GLU D 2 405 ? 99.886  15.875  108.967 1.00 52.61  ? 405  GLU B C     1 
ATOM   10338 O  O     . GLU D 2 405 ? 100.716 16.676  108.537 1.00 55.42  ? 405  GLU B O     1 
ATOM   10339 C  CB    . GLU D 2 405 ? 100.342 13.425  108.771 1.00 55.72  ? 405  GLU B CB    1 
ATOM   10340 C  CG    . GLU D 2 405 ? 101.732 12.917  108.402 1.00 77.08  ? 405  GLU B CG    1 
ATOM   10341 C  CD    . GLU D 2 405 ? 102.382 13.711  107.272 1.00 88.94  ? 405  GLU B CD    1 
ATOM   10342 O  OE1   . GLU D 2 405 ? 103.401 13.234  106.716 1.00 89.60  ? 405  GLU B OE1   1 
ATOM   10343 O  OE2   . GLU D 2 405 ? 101.875 14.809  106.939 1.00 94.24  ? 405  GLU B OE2   1 
ATOM   10344 N  N     . GLU D 2 406 ? 98.577  16.060  108.832 1.00 46.50  ? 406  GLU B N     1 
ATOM   10345 C  CA    . GLU D 2 406 ? 98.039  17.215  108.119 1.00 50.54  ? 406  GLU B CA    1 
ATOM   10346 C  C     . GLU D 2 406 ? 97.703  18.385  109.064 1.00 47.84  ? 406  GLU B C     1 
ATOM   10347 O  O     . GLU D 2 406 ? 96.624  18.427  109.653 1.00 46.59  ? 406  GLU B O     1 
ATOM   10348 C  CB    . GLU D 2 406 ? 96.790  16.786  107.349 1.00 46.59  ? 406  GLU B CB    1 
ATOM   10349 C  CG    . GLU D 2 406 ? 96.414  17.723  106.246 1.00 63.47  ? 406  GLU B CG    1 
ATOM   10350 C  CD    . GLU D 2 406 ? 95.420  17.118  105.276 1.00 69.99  ? 406  GLU B CD    1 
ATOM   10351 O  OE1   . GLU D 2 406 ? 95.764  16.105  104.625 1.00 75.65  ? 406  GLU B OE1   1 
ATOM   10352 O  OE2   . GLU D 2 406 ? 94.297  17.661  105.166 1.00 74.61  ? 406  GLU B OE2   1 
ATOM   10353 N  N     . TRP D 2 407 ? 98.620  19.345  109.177 1.00 41.91  ? 407  TRP B N     1 
ATOM   10354 C  CA    . TRP D 2 407 ? 98.445  20.493  110.062 1.00 36.85  ? 407  TRP B CA    1 
ATOM   10355 C  C     . TRP D 2 407 ? 97.807  21.684  109.367 1.00 39.63  ? 407  TRP B C     1 
ATOM   10356 O  O     . TRP D 2 407 ? 98.494  22.643  109.005 1.00 38.91  ? 407  TRP B O     1 
ATOM   10357 C  CB    . TRP D 2 407 ? 99.797  20.901  110.641 1.00 36.70  ? 407  TRP B CB    1 
ATOM   10358 C  CG    . TRP D 2 407 ? 99.703  21.628  111.934 1.00 35.21  ? 407  TRP B CG    1 
ATOM   10359 C  CD1   . TRP D 2 407 ? 99.742  22.977  112.117 1.00 20.90  ? 407  TRP B CD1   1 
ATOM   10360 C  CD2   . TRP D 2 407 ? 99.562  21.048  113.236 1.00 27.49  ? 407  TRP B CD2   1 
ATOM   10361 N  NE1   . TRP D 2 407 ? 99.637  23.273  113.446 1.00 27.13  ? 407  TRP B NE1   1 
ATOM   10362 C  CE2   . TRP D 2 407 ? 99.526  22.112  114.162 1.00 22.89  ? 407  TRP B CE2   1 
ATOM   10363 C  CE3   . TRP D 2 407 ? 99.463  19.734  113.710 1.00 25.12  ? 407  TRP B CE3   1 
ATOM   10364 C  CZ2   . TRP D 2 407 ? 99.393  21.911  115.545 1.00 23.47  ? 407  TRP B CZ2   1 
ATOM   10365 C  CZ3   . TRP D 2 407 ? 99.330  19.529  115.099 1.00 22.42  ? 407  TRP B CZ3   1 
ATOM   10366 C  CH2   . TRP D 2 407 ? 99.296  20.618  115.993 1.00 16.59  ? 407  TRP B CH2   1 
ATOM   10367 N  N     . THR D 2 408 ? 96.491  21.608  109.197 1.00 34.53  ? 408  THR B N     1 
ATOM   10368 C  CA    . THR D 2 408 ? 95.697  22.653  108.563 1.00 33.48  ? 408  THR B CA    1 
ATOM   10369 C  C     . THR D 2 408 ? 94.439  22.899  109.375 1.00 35.33  ? 408  THR B C     1 
ATOM   10370 O  O     . THR D 2 408 ? 94.032  22.073  110.194 1.00 38.30  ? 408  THR B O     1 
ATOM   10371 C  CB    . THR D 2 408 ? 95.248  22.252  107.140 1.00 42.85  ? 408  THR B CB    1 
ATOM   10372 O  OG1   . THR D 2 408 ? 94.625  20.960  107.183 1.00 44.36  ? 408  THR B OG1   1 
ATOM   10373 C  CG2   . THR D 2 408 ? 96.439  22.216  106.179 1.00 51.01  ? 408  THR B CG2   1 
ATOM   10374 N  N     . GLU D 2 409 ? 93.813  24.038  109.135 1.00 40.12  ? 409  GLU B N     1 
ATOM   10375 C  CA    . GLU D 2 409 ? 92.591  24.396  109.836 1.00 39.11  ? 409  GLU B CA    1 
ATOM   10376 C  C     . GLU D 2 409 ? 91.505  23.322  109.713 1.00 36.38  ? 409  GLU B C     1 
ATOM   10377 O  O     . GLU D 2 409 ? 90.870  22.960  110.695 1.00 40.65  ? 409  GLU B O     1 
ATOM   10378 C  CB    . GLU D 2 409 ? 92.076  25.745  109.315 1.00 34.13  ? 409  GLU B CB    1 
ATOM   10379 C  CG    . GLU D 2 409 ? 92.772  26.934  109.956 1.00 53.13  ? 409  GLU B CG    1 
ATOM   10380 C  CD    . GLU D 2 409 ? 92.733  28.198  109.104 1.00 62.44  ? 409  GLU B CD    1 
ATOM   10381 O  OE1   . GLU D 2 409 ? 93.716  28.443  108.363 1.00 52.79  ? 409  GLU B OE1   1 
ATOM   10382 O  OE2   . GLU D 2 409 ? 91.721  28.942  109.176 1.00 72.61  ? 409  GLU B OE2   1 
ATOM   10383 N  N     . ALA D 2 410 ? 91.289  22.813  108.510 1.00 32.98  ? 410  ALA B N     1 
ATOM   10384 C  CA    . ALA D 2 410 ? 90.260  21.800  108.298 1.00 38.86  ? 410  ALA B CA    1 
ATOM   10385 C  C     . ALA D 2 410 ? 90.535  20.522  109.084 1.00 35.67  ? 410  ALA B C     1 
ATOM   10386 O  O     . ALA D 2 410 ? 89.722  20.090  109.900 1.00 36.43  ? 410  ALA B O     1 
ATOM   10387 C  CB    . ALA D 2 410 ? 90.121  21.478  106.789 1.00 30.89  ? 410  ALA B CB    1 
ATOM   10388 N  N     . ALA D 2 411 ? 91.682  19.913  108.839 1.00 36.29  ? 411  ALA B N     1 
ATOM   10389 C  CA    . ALA D 2 411 ? 92.010  18.687  109.545 1.00 36.71  ? 411  ALA B CA    1 
ATOM   10390 C  C     . ALA D 2 411 ? 92.065  18.902  111.072 1.00 36.92  ? 411  ALA B C     1 
ATOM   10391 O  O     . ALA D 2 411 ? 91.579  18.074  111.843 1.00 37.39  ? 411  ALA B O     1 
ATOM   10392 C  CB    . ALA D 2 411 ? 93.321  18.145  109.028 1.00 32.21  ? 411  ALA B CB    1 
ATOM   10393 N  N     . LEU D 2 412 ? 92.633  20.022  111.506 1.00 30.68  ? 412  LEU B N     1 
ATOM   10394 C  CA    . LEU D 2 412 ? 92.726  20.301  112.926 1.00 34.45  ? 412  LEU B CA    1 
ATOM   10395 C  C     . LEU D 2 412 ? 91.322  20.490  113.496 1.00 32.10  ? 412  LEU B C     1 
ATOM   10396 O  O     . LEU D 2 412 ? 91.055  20.115  114.631 1.00 34.79  ? 412  LEU B O     1 
ATOM   10397 C  CB    . LEU D 2 412 ? 93.577  21.543  113.172 1.00 30.63  ? 412  LEU B CB    1 
ATOM   10398 C  CG    . LEU D 2 412 ? 95.069  21.537  113.528 1.00 31.83  ? 412  LEU B CG    1 
ATOM   10399 C  CD1   . LEU D 2 412 ? 95.693  20.169  113.513 1.00 33.21  ? 412  LEU B CD1   1 
ATOM   10400 C  CD2   . LEU D 2 412 ? 95.768  22.459  112.570 1.00 27.28  ? 412  LEU B CD2   1 
ATOM   10401 N  N     . GLU D 2 413 ? 90.407  21.049  112.715 1.00 35.11  ? 413  GLU B N     1 
ATOM   10402 C  CA    . GLU D 2 413 ? 89.053  21.210  113.233 1.00 36.55  ? 413  GLU B CA    1 
ATOM   10403 C  C     . GLU D 2 413 ? 88.397  19.836  113.353 1.00 34.61  ? 413  GLU B C     1 
ATOM   10404 O  O     . GLU D 2 413 ? 87.777  19.508  114.370 1.00 39.91  ? 413  GLU B O     1 
ATOM   10405 C  CB    . GLU D 2 413 ? 88.191  22.116  112.345 1.00 38.58  ? 413  GLU B CB    1 
ATOM   10406 C  CG    . GLU D 2 413 ? 86.704  21.999  112.733 1.00 49.94  ? 413  GLU B CG    1 
ATOM   10407 C  CD    . GLU D 2 413 ? 85.839  23.153  112.283 1.00 51.78  ? 413  GLU B CD    1 
ATOM   10408 O  OE1   . GLU D 2 413 ? 86.287  23.947  111.420 1.00 59.03  ? 413  GLU B OE1   1 
ATOM   10409 O  OE2   . GLU D 2 413 ? 84.697  23.252  112.795 1.00 47.68  ? 413  GLU B OE2   1 
ATOM   10410 N  N     . ALA D 2 414 ? 88.534  19.029  112.318 1.00 26.69  ? 414  ALA B N     1 
ATOM   10411 C  CA    . ALA D 2 414 ? 87.963  17.693  112.376 1.00 39.62  ? 414  ALA B CA    1 
ATOM   10412 C  C     . ALA D 2 414 ? 88.566  16.903  113.555 1.00 42.13  ? 414  ALA B C     1 
ATOM   10413 O  O     . ALA D 2 414 ? 87.834  16.231  114.289 1.00 44.60  ? 414  ALA B O     1 
ATOM   10414 C  CB    . ALA D 2 414 ? 88.213  16.955  111.070 1.00 28.06  ? 414  ALA B CB    1 
ATOM   10415 N  N     . LEU D 2 415 ? 89.887  16.988  113.740 1.00 39.79  ? 415  LEU B N     1 
ATOM   10416 C  CA    . LEU D 2 415 ? 90.544  16.269  114.828 1.00 34.82  ? 415  LEU B CA    1 
ATOM   10417 C  C     . LEU D 2 415 ? 90.054  16.710  116.216 1.00 36.75  ? 415  LEU B C     1 
ATOM   10418 O  O     . LEU D 2 415 ? 89.865  15.887  117.110 1.00 32.91  ? 415  LEU B O     1 
ATOM   10419 C  CB    . LEU D 2 415 ? 92.065  16.442  114.752 1.00 33.30  ? 415  LEU B CB    1 
ATOM   10420 C  CG    . LEU D 2 415 ? 92.876  15.852  115.925 1.00 35.95  ? 415  LEU B CG    1 
ATOM   10421 C  CD1   . LEU D 2 415 ? 92.860  14.353  115.828 1.00 39.85  ? 415  LEU B CD1   1 
ATOM   10422 C  CD2   . LEU D 2 415 ? 94.338  16.306  115.882 1.00 37.98  ? 415  LEU B CD2   1 
ATOM   10423 N  N     . LEU D 2 416 ? 89.846  18.005  116.409 1.00 34.33  ? 416  LEU B N     1 
ATOM   10424 C  CA    . LEU D 2 416 ? 89.403  18.458  117.725 1.00 38.62  ? 416  LEU B CA    1 
ATOM   10425 C  C     . LEU D 2 416 ? 87.918  18.211  118.012 1.00 38.99  ? 416  LEU B C     1 
ATOM   10426 O  O     . LEU D 2 416 ? 87.535  18.007  119.159 1.00 29.83  ? 416  LEU B O     1 
ATOM   10427 C  CB    . LEU D 2 416 ? 89.722  19.932  117.910 1.00 41.15  ? 416  LEU B CB    1 
ATOM   10428 C  CG    . LEU D 2 416 ? 91.202  20.271  117.969 1.00 43.08  ? 416  LEU B CG    1 
ATOM   10429 C  CD1   . LEU D 2 416 ? 91.369  21.733  117.629 1.00 47.99  ? 416  LEU B CD1   1 
ATOM   10430 C  CD2   . LEU D 2 416 ? 91.760  19.947  119.353 1.00 49.53  ? 416  LEU B CD2   1 
ATOM   10431 N  N     . ARG D 2 417 ? 87.073  18.257  116.989 1.00 38.29  ? 417  ARG B N     1 
ATOM   10432 C  CA    . ARG D 2 417 ? 85.662  17.977  117.228 1.00 39.66  ? 417  ARG B CA    1 
ATOM   10433 C  C     . ARG D 2 417 ? 85.505  16.471  117.477 1.00 46.34  ? 417  ARG B C     1 
ATOM   10434 O  O     . ARG D 2 417 ? 84.698  16.036  118.320 1.00 45.99  ? 417  ARG B O     1 
ATOM   10435 C  CB    . ARG D 2 417 ? 84.808  18.416  116.040 1.00 29.54  ? 417  ARG B CB    1 
ATOM   10436 C  CG    . ARG D 2 417 ? 84.638  19.930  115.935 1.00 25.66  ? 417  ARG B CG    1 
ATOM   10437 C  CD    . ARG D 2 417 ? 83.741  20.289  114.774 1.00 31.21  ? 417  ARG B CD    1 
ATOM   10438 N  NE    . ARG D 2 417 ? 83.656  21.731  114.583 1.00 27.79  ? 417  ARG B NE    1 
ATOM   10439 C  CZ    . ARG D 2 417 ? 82.976  22.559  115.371 1.00 33.85  ? 417  ARG B CZ    1 
ATOM   10440 N  NH1   . ARG D 2 417 ? 82.300  22.094  116.415 1.00 37.20  ? 417  ARG B NH1   1 
ATOM   10441 N  NH2   . ARG D 2 417 ? 82.992  23.862  115.124 1.00 31.51  ? 417  ARG B NH2   1 
ATOM   10442 N  N     . GLY D 2 418 ? 86.289  15.674  116.759 1.00 41.72  ? 418  GLY B N     1 
ATOM   10443 C  CA    . GLY D 2 418 ? 86.204  14.241  116.949 1.00 43.55  ? 418  GLY B CA    1 
ATOM   10444 C  C     . GLY D 2 418 ? 86.687  13.901  118.346 1.00 41.39  ? 418  GLY B C     1 
ATOM   10445 O  O     . GLY D 2 418 ? 86.081  13.106  119.060 1.00 53.41  ? 418  GLY B O     1 
ATOM   10446 N  N     . PHE D 2 419 ? 87.779  14.527  118.754 1.00 40.90  ? 419  PHE B N     1 
ATOM   10447 C  CA    . PHE D 2 419 ? 88.344  14.268  120.066 1.00 38.79  ? 419  PHE B CA    1 
ATOM   10448 C  C     . PHE D 2 419 ? 87.345  14.600  121.149 1.00 39.75  ? 419  PHE B C     1 
ATOM   10449 O  O     . PHE D 2 419 ? 87.109  13.800  122.039 1.00 45.59  ? 419  PHE B O     1 
ATOM   10450 C  CB    . PHE D 2 419 ? 89.610  15.078  120.269 1.00 24.42  ? 419  PHE B CB    1 
ATOM   10451 C  CG    . PHE D 2 419 ? 90.181  14.938  121.627 1.00 31.49  ? 419  PHE B CG    1 
ATOM   10452 C  CD1   . PHE D 2 419 ? 89.991  15.939  122.581 1.00 31.47  ? 419  PHE B CD1   1 
ATOM   10453 C  CD2   . PHE D 2 419 ? 90.890  13.792  121.976 1.00 35.30  ? 419  PHE B CD2   1 
ATOM   10454 C  CE1   . PHE D 2 419 ? 90.501  15.813  123.873 1.00 32.75  ? 419  PHE B CE1   1 
ATOM   10455 C  CE2   . PHE D 2 419 ? 91.410  13.653  123.266 1.00 40.47  ? 419  PHE B CE2   1 
ATOM   10456 C  CZ    . PHE D 2 419 ? 91.209  14.681  124.218 1.00 32.26  ? 419  PHE B CZ    1 
ATOM   10457 N  N     . ALA D 2 420 ? 86.757  15.786  121.063 1.00 39.99  ? 420  ALA B N     1 
ATOM   10458 C  CA    . ALA D 2 420 ? 85.754  16.224  122.031 1.00 47.11  ? 420  ALA B CA    1 
ATOM   10459 C  C     . ALA D 2 420 ? 84.563  15.246  122.079 1.00 45.24  ? 420  ALA B C     1 
ATOM   10460 O  O     . ALA D 2 420 ? 84.111  14.857  123.151 1.00 42.70  ? 420  ALA B O     1 
ATOM   10461 C  CB    . ALA D 2 420 ? 85.264  17.629  121.667 1.00 43.09  ? 420  ALA B CB    1 
ATOM   10462 N  N     . ALA D 2 421 ? 84.056  14.864  120.914 1.00 42.52  ? 421  ALA B N     1 
ATOM   10463 C  CA    . ALA D 2 421 ? 82.933  13.930  120.855 1.00 46.30  ? 421  ALA B CA    1 
ATOM   10464 C  C     . ALA D 2 421 ? 83.322  12.625  121.526 1.00 49.40  ? 421  ALA B C     1 
ATOM   10465 O  O     . ALA D 2 421 ? 82.621  12.129  122.397 1.00 50.99  ? 421  ALA B O     1 
ATOM   10466 C  CB    . ALA D 2 421 ? 82.553  13.669  119.417 1.00 40.79  ? 421  ALA B CB    1 
ATOM   10467 N  N     . GLU D 2 422 ? 84.461  12.084  121.112 1.00 53.83  ? 422  GLU B N     1 
ATOM   10468 C  CA    . GLU D 2 422 ? 84.985  10.837  121.650 1.00 47.61  ? 422  GLU B CA    1 
ATOM   10469 C  C     . GLU D 2 422 ? 85.046  10.877  123.162 1.00 46.85  ? 422  GLU B C     1 
ATOM   10470 O  O     . GLU D 2 422 ? 84.970  9.846   123.829 1.00 53.56  ? 422  GLU B O     1 
ATOM   10471 C  CB    . GLU D 2 422 ? 86.401  10.590  121.107 1.00 53.75  ? 422  GLU B CB    1 
ATOM   10472 C  CG    . GLU D 2 422 ? 87.063  9.292   121.594 1.00 61.21  ? 422  GLU B CG    1 
ATOM   10473 C  CD    . GLU D 2 422 ? 88.581  9.272   121.387 1.00 65.36  ? 422  GLU B CD    1 
ATOM   10474 O  OE1   . GLU D 2 422 ? 89.046  9.668   120.289 1.00 64.93  ? 422  GLU B OE1   1 
ATOM   10475 O  OE2   . GLU D 2 422 ? 89.306  8.852   122.324 1.00 62.42  ? 422  GLU B OE2   1 
ATOM   10476 N  N     . LYS D 2 423 ? 85.187  12.071  123.710 1.00 41.59  ? 423  LYS B N     1 
ATOM   10477 C  CA    . LYS D 2 423 ? 85.306  12.192  125.144 1.00 43.76  ? 423  LYS B CA    1 
ATOM   10478 C  C     . LYS D 2 423 ? 84.031  12.712  125.772 1.00 43.64  ? 423  LYS B C     1 
ATOM   10479 O  O     . LYS D 2 423 ? 84.022  13.049  126.953 1.00 41.37  ? 423  LYS B O     1 
ATOM   10480 C  CB    . LYS D 2 423 ? 86.476  13.118  125.476 1.00 44.90  ? 423  LYS B CB    1 
ATOM   10481 C  CG    . LYS D 2 423 ? 86.951  13.003  126.894 1.00 60.55  ? 423  LYS B CG    1 
ATOM   10482 C  CD    . LYS D 2 423 ? 88.443  12.676  126.950 1.00 70.88  ? 423  LYS B CD    1 
ATOM   10483 C  CE    . LYS D 2 423 ? 88.807  11.454  126.112 1.00 77.14  ? 423  LYS B CE    1 
ATOM   10484 N  NZ    . LYS D 2 423 ? 88.625  11.693  124.650 1.00 74.40  ? 423  LYS B NZ    1 
ATOM   10485 N  N     . GLY D 2 424 ? 82.967  12.785  124.970 1.00 42.97  ? 424  GLY B N     1 
ATOM   10486 C  CA    . GLY D 2 424 ? 81.676  13.268  125.451 1.00 50.47  ? 424  GLY B CA    1 
ATOM   10487 C  C     . GLY D 2 424 ? 81.775  14.633  126.110 1.00 51.26  ? 424  GLY B C     1 
ATOM   10488 O  O     . GLY D 2 424 ? 81.219  14.871  127.190 1.00 54.10  ? 424  GLY B O     1 
ATOM   10489 N  N     . VAL D 2 425 ? 82.475  15.539  125.435 1.00 47.81  ? 425  VAL B N     1 
ATOM   10490 C  CA    . VAL D 2 425 ? 82.705  16.884  125.936 1.00 40.08  ? 425  VAL B CA    1 
ATOM   10491 C  C     . VAL D 2 425 ? 82.396  17.921  124.851 1.00 40.03  ? 425  VAL B C     1 
ATOM   10492 O  O     . VAL D 2 425 ? 82.384  17.590  123.651 1.00 35.66  ? 425  VAL B O     1 
ATOM   10493 C  CB    . VAL D 2 425 ? 84.180  16.963  126.389 1.00 43.13  ? 425  VAL B CB    1 
ATOM   10494 C  CG1   . VAL D 2 425 ? 84.852  18.191  125.849 1.00 28.54  ? 425  VAL B CG1   1 
ATOM   10495 C  CG2   . VAL D 2 425 ? 84.248  16.871  127.895 1.00 32.07  ? 425  VAL B CG2   1 
ATOM   10496 N  N     . LYS D 2 426 ? 82.112  19.155  125.265 1.00 32.64  ? 426  LYS B N     1 
ATOM   10497 C  CA    . LYS D 2 426 ? 81.853  20.243  124.306 1.00 39.19  ? 426  LYS B CA    1 
ATOM   10498 C  C     . LYS D 2 426 ? 83.217  20.730  123.764 1.00 37.64  ? 426  LYS B C     1 
ATOM   10499 O  O     . LYS D 2 426 ? 84.193  20.803  124.531 1.00 37.17  ? 426  LYS B O     1 
ATOM   10500 C  CB    . LYS D 2 426 ? 81.168  21.427  125.007 1.00 41.94  ? 426  LYS B CB    1 
ATOM   10501 C  CG    . LYS D 2 426 ? 79.751  21.170  125.527 1.00 39.82  ? 426  LYS B CG    1 
ATOM   10502 C  CD    . LYS D 2 426 ? 78.839  20.791  124.379 1.00 48.08  ? 426  LYS B CD    1 
ATOM   10503 C  CE    . LYS D 2 426 ? 77.473  21.443  124.514 1.00 53.83  ? 426  LYS B CE    1 
ATOM   10504 N  NZ    . LYS D 2 426 ? 77.596  22.931  124.458 1.00 41.25  ? 426  LYS B NZ    1 
ATOM   10505 N  N     . LEU D 2 427 ? 83.300  21.065  122.472 1.00 33.16  ? 427  LEU B N     1 
ATOM   10506 C  CA    . LEU D 2 427 ? 84.570  21.572  121.901 1.00 34.25  ? 427  LEU B CA    1 
ATOM   10507 C  C     . LEU D 2 427 ? 85.165  22.669  122.783 1.00 36.55  ? 427  LEU B C     1 
ATOM   10508 O  O     . LEU D 2 427 ? 86.342  22.641  123.135 1.00 37.56  ? 427  LEU B O     1 
ATOM   10509 C  CB    . LEU D 2 427 ? 84.360  22.140  120.500 1.00 31.93  ? 427  LEU B CB    1 
ATOM   10510 C  CG    . LEU D 2 427 ? 85.571  22.781  119.797 1.00 41.09  ? 427  LEU B CG    1 
ATOM   10511 C  CD1   . LEU D 2 427 ? 86.678  21.758  119.593 1.00 36.05  ? 427  LEU B CD1   1 
ATOM   10512 C  CD2   . LEU D 2 427 ? 85.128  23.340  118.438 1.00 42.27  ? 427  LEU B CD2   1 
ATOM   10513 N  N     . GLY D 2 428 ? 84.332  23.631  123.155 1.00 42.24  ? 428  GLY B N     1 
ATOM   10514 C  CA    . GLY D 2 428 ? 84.786  24.717  124.004 1.00 38.39  ? 428  GLY B CA    1 
ATOM   10515 C  C     . GLY D 2 428 ? 85.588  24.217  125.182 1.00 44.55  ? 428  GLY B C     1 
ATOM   10516 O  O     . GLY D 2 428 ? 86.536  24.878  125.645 1.00 44.68  ? 428  GLY B O     1 
ATOM   10517 N  N     . GLN D 2 429 ? 85.224  23.039  125.668 1.00 39.23  ? 429  GLN B N     1 
ATOM   10518 C  CA    . GLN D 2 429 ? 85.933  22.467  126.798 1.00 46.75  ? 429  GLN B CA    1 
ATOM   10519 C  C     . GLN D 2 429 ? 87.366  22.055  126.453 1.00 45.22  ? 429  GLN B C     1 
ATOM   10520 O  O     . GLN D 2 429 ? 88.219  21.923  127.343 1.00 33.73  ? 429  GLN B O     1 
ATOM   10521 C  CB    . GLN D 2 429 ? 85.154  21.283  127.331 1.00 45.82  ? 429  GLN B CB    1 
ATOM   10522 C  CG    . GLN D 2 429 ? 84.031  21.720  128.220 1.00 52.88  ? 429  GLN B CG    1 
ATOM   10523 C  CD    . GLN D 2 429 ? 83.116  20.590  128.572 1.00 55.13  ? 429  GLN B CD    1 
ATOM   10524 O  OE1   . GLN D 2 429 ? 82.286  20.172  127.758 1.00 47.85  ? 429  GLN B OE1   1 
ATOM   10525 N  NE2   . GLN D 2 429 ? 83.267  20.071  129.786 1.00 52.48  ? 429  GLN B NE2   1 
ATOM   10526 N  N     . VAL D 2 430 ? 87.611  21.852  125.160 1.00 37.53  ? 430  VAL B N     1 
ATOM   10527 C  CA    . VAL D 2 430 ? 88.933  21.464  124.666 1.00 40.99  ? 430  VAL B CA    1 
ATOM   10528 C  C     . VAL D 2 430 ? 89.596  22.686  124.040 1.00 40.37  ? 430  VAL B C     1 
ATOM   10529 O  O     . VAL D 2 430 ? 90.771  22.944  124.259 1.00 33.04  ? 430  VAL B O     1 
ATOM   10530 C  CB    . VAL D 2 430 ? 88.838  20.351  123.589 1.00 38.97  ? 430  VAL B CB    1 
ATOM   10531 C  CG1   . VAL D 2 430 ? 90.217  19.995  123.060 1.00 32.59  ? 430  VAL B CG1   1 
ATOM   10532 C  CG2   . VAL D 2 430 ? 88.169  19.129  124.176 1.00 40.00  ? 430  VAL B CG2   1 
ATOM   10533 N  N     . ALA D 2 431 ? 88.821  23.442  123.272 1.00 40.18  ? 431  ALA B N     1 
ATOM   10534 C  CA    . ALA D 2 431 ? 89.324  24.632  122.602 1.00 38.38  ? 431  ALA B CA    1 
ATOM   10535 C  C     . ALA D 2 431 ? 89.795  25.731  123.558 1.00 34.31  ? 431  ALA B C     1 
ATOM   10536 O  O     . ALA D 2 431 ? 90.862  26.304  123.368 1.00 31.76  ? 431  ALA B O     1 
ATOM   10537 C  CB    . ALA D 2 431 ? 88.248  25.179  121.650 1.00 40.93  ? 431  ALA B CB    1 
ATOM   10538 N  N     . GLN D 2 432 ? 89.014  26.016  124.589 1.00 30.18  ? 432  GLN B N     1 
ATOM   10539 C  CA    . GLN D 2 432 ? 89.389  27.066  125.526 1.00 31.03  ? 432  GLN B CA    1 
ATOM   10540 C  C     . GLN D 2 432 ? 90.702  26.804  126.248 1.00 28.94  ? 432  GLN B C     1 
ATOM   10541 O  O     . GLN D 2 432 ? 91.593  27.659  126.268 1.00 37.95  ? 432  GLN B O     1 
ATOM   10542 C  CB    . GLN D 2 432 ? 88.264  27.301  126.533 1.00 27.44  ? 432  GLN B CB    1 
ATOM   10543 C  CG    . GLN D 2 432 ? 88.213  28.689  127.084 1.00 40.81  ? 432  GLN B CG    1 
ATOM   10544 C  CD    . GLN D 2 432 ? 87.774  29.773  126.060 1.00 49.08  ? 432  GLN B CD    1 
ATOM   10545 O  OE1   . GLN D 2 432 ? 87.037  30.690  126.424 1.00 49.54  ? 432  GLN B OE1   1 
ATOM   10546 N  NE2   . GLN D 2 432 ? 88.242  29.684  124.810 1.00 33.80  ? 432  GLN B NE2   1 
ATOM   10547 N  N     . PRO D 2 433 ? 90.843  25.634  126.881 1.00 37.87  ? 433  PRO B N     1 
ATOM   10548 C  CA    . PRO D 2 433 ? 92.130  25.396  127.564 1.00 34.63  ? 433  PRO B CA    1 
ATOM   10549 C  C     . PRO D 2 433 ? 93.320  25.397  126.570 1.00 35.00  ? 433  PRO B C     1 
ATOM   10550 O  O     . PRO D 2 433 ? 94.417  25.910  126.858 1.00 38.34  ? 433  PRO B O     1 
ATOM   10551 C  CB    . PRO D 2 433 ? 91.919  24.051  128.287 1.00 37.07  ? 433  PRO B CB    1 
ATOM   10552 C  CG    . PRO D 2 433 ? 90.645  23.493  127.727 1.00 39.76  ? 433  PRO B CG    1 
ATOM   10553 C  CD    . PRO D 2 433 ? 89.813  24.665  127.299 1.00 32.29  ? 433  PRO B CD    1 
ATOM   10554 N  N     . LEU D 2 434 ? 93.100  24.866  125.380 1.00 26.68  ? 434  LEU B N     1 
ATOM   10555 C  CA    . LEU D 2 434 ? 94.154  24.878  124.378 1.00 32.83  ? 434  LEU B CA    1 
ATOM   10556 C  C     . LEU D 2 434 ? 94.507  26.335  123.955 1.00 30.23  ? 434  LEU B C     1 
ATOM   10557 O  O     . LEU D 2 434 ? 95.674  26.661  123.732 1.00 35.01  ? 434  LEU B O     1 
ATOM   10558 C  CB    . LEU D 2 434 ? 93.718  24.036  123.180 1.00 21.63  ? 434  LEU B CB    1 
ATOM   10559 C  CG    . LEU D 2 434 ? 94.686  23.958  122.013 1.00 25.26  ? 434  LEU B CG    1 
ATOM   10560 C  CD1   . LEU D 2 434 ? 96.003  23.394  122.483 1.00 33.38  ? 434  LEU B CD1   1 
ATOM   10561 C  CD2   . LEU D 2 434 ? 94.071  23.100  120.919 1.00 24.37  ? 434  LEU B CD2   1 
ATOM   10562 N  N     . ARG D 2 435 ? 93.499  27.199  123.861 1.00 31.61  ? 435  ARG B N     1 
ATOM   10563 C  CA    . ARG D 2 435 ? 93.713  28.599  123.505 1.00 32.81  ? 435  ARG B CA    1 
ATOM   10564 C  C     . ARG D 2 435 ? 94.644  29.208  124.565 1.00 32.62  ? 435  ARG B C     1 
ATOM   10565 O  O     . ARG D 2 435 ? 95.624  29.880  124.243 1.00 34.45  ? 435  ARG B O     1 
ATOM   10566 C  CB    . ARG D 2 435 ? 92.369  29.361  123.461 1.00 23.33  ? 435  ARG B CB    1 
ATOM   10567 C  CG    . ARG D 2 435 ? 92.526  30.867  123.268 1.00 32.24  ? 435  ARG B CG    1 
ATOM   10568 C  CD    . ARG D 2 435 ? 91.293  31.595  122.633 1.00 21.98  ? 435  ARG B CD    1 
ATOM   10569 N  NE    . ARG D 2 435 ? 90.126  30.755  122.567 1.00 40.87  ? 435  ARG B NE    1 
ATOM   10570 C  CZ    . ARG D 2 435 ? 89.541  30.358  121.445 1.00 34.58  ? 435  ARG B CZ    1 
ATOM   10571 N  NH1   . ARG D 2 435 ? 90.002  30.717  120.254 1.00 30.48  ? 435  ARG B NH1   1 
ATOM   10572 N  NH2   . ARG D 2 435 ? 88.477  29.587  121.534 1.00 41.84  ? 435  ARG B NH2   1 
ATOM   10573 N  N     . ALA D 2 436 ? 94.337  28.953  125.831 1.00 32.43  ? 436  ALA B N     1 
ATOM   10574 C  CA    . ALA D 2 436 ? 95.148  29.456  126.938 1.00 30.50  ? 436  ALA B CA    1 
ATOM   10575 C  C     . ALA D 2 436 ? 96.611  28.976  126.840 1.00 33.69  ? 436  ALA B C     1 
ATOM   10576 O  O     . ALA D 2 436 ? 97.543  29.740  127.074 1.00 31.81  ? 436  ALA B O     1 
ATOM   10577 C  CB    . ALA D 2 436 ? 94.540  28.986  128.265 1.00 29.65  ? 436  ALA B CB    1 
ATOM   10578 N  N     . ALA D 2 437 ? 96.813  27.705  126.497 1.00 35.76  ? 437  ALA B N     1 
ATOM   10579 C  CA    . ALA D 2 437 ? 98.161  27.160  126.402 1.00 25.86  ? 437  ALA B CA    1 
ATOM   10580 C  C     . ALA D 2 437 ? 98.976  27.761  125.250 1.00 35.35  ? 437  ALA B C     1 
ATOM   10581 O  O     . ALA D 2 437 ? 100.183 27.975  125.376 1.00 34.57  ? 437  ALA B O     1 
ATOM   10582 C  CB    . ALA D 2 437 ? 98.092  25.655  126.264 1.00 23.92  ? 437  ALA B CB    1 
ATOM   10583 N  N     . LEU D 2 438 ? 98.315  28.027  124.126 1.00 36.74  ? 438  LEU B N     1 
ATOM   10584 C  CA    . LEU D 2 438 ? 98.982  28.592  122.966 1.00 32.57  ? 438  LEU B CA    1 
ATOM   10585 C  C     . LEU D 2 438 ? 99.127  30.115  122.972 1.00 38.03  ? 438  LEU B C     1 
ATOM   10586 O  O     . LEU D 2 438 ? 99.991  30.641  122.274 1.00 29.68  ? 438  LEU B O     1 
ATOM   10587 C  CB    . LEU D 2 438 ? 98.225  28.204  121.697 1.00 35.99  ? 438  LEU B CB    1 
ATOM   10588 C  CG    . LEU D 2 438 ? 98.119  26.727  121.304 1.00 46.31  ? 438  LEU B CG    1 
ATOM   10589 C  CD1   . LEU D 2 438 ? 97.220  26.617  120.090 1.00 32.36  ? 438  LEU B CD1   1 
ATOM   10590 C  CD2   . LEU D 2 438 ? 99.507  26.127  121.008 1.00 31.67  ? 438  LEU B CD2   1 
ATOM   10591 N  N     . THR D 2 439 ? 98.299  30.829  123.740 1.00 33.23  ? 439  THR B N     1 
ATOM   10592 C  CA    . THR D 2 439 ? 98.359  32.285  123.689 1.00 34.33  ? 439  THR B CA    1 
ATOM   10593 C  C     . THR D 2 439 ? 98.538  33.029  124.999 1.00 29.29  ? 439  THR B C     1 
ATOM   10594 O  O     . THR D 2 439 ? 98.973  34.173  124.993 1.00 27.88  ? 439  THR B O     1 
ATOM   10595 C  CB    . THR D 2 439 ? 97.100  32.857  123.017 1.00 34.72  ? 439  THR B CB    1 
ATOM   10596 O  OG1   . THR D 2 439 ? 95.998  32.762  123.923 1.00 33.52  ? 439  THR B OG1   1 
ATOM   10597 C  CG2   . THR D 2 439 ? 96.763  32.078  121.772 1.00 28.37  ? 439  THR B CG2   1 
ATOM   10598 N  N     . GLY D 2 440 ? 98.200  32.389  126.108 1.00 28.19  ? 440  GLY B N     1 
ATOM   10599 C  CA    . GLY D 2 440 ? 98.326  33.035  127.402 1.00 28.65  ? 440  GLY B CA    1 
ATOM   10600 C  C     . GLY D 2 440 ? 97.095  33.883  127.623 1.00 32.58  ? 440  GLY B C     1 
ATOM   10601 O  O     . GLY D 2 440 ? 97.025  34.664  128.572 1.00 37.82  ? 440  GLY B O     1 
ATOM   10602 N  N     . SER D 2 441 ? 96.111  33.693  126.745 1.00 32.30  ? 441  SER B N     1 
ATOM   10603 C  CA    . SER D 2 441 ? 94.869  34.452  126.784 1.00 30.15  ? 441  SER B CA    1 
ATOM   10604 C  C     . SER D 2 441 ? 93.576  33.691  126.392 1.00 33.12  ? 441  SER B C     1 
ATOM   10605 O  O     . SER D 2 441 ? 93.591  32.653  125.740 1.00 29.34  ? 441  SER B O     1 
ATOM   10606 C  CB    . SER D 2 441 ? 95.039  35.698  125.892 1.00 22.92  ? 441  SER B CB    1 
ATOM   10607 O  OG    . SER D 2 441 ? 93.799  36.325  125.571 1.00 30.13  ? 441  SER B OG    1 
ATOM   10608 N  N     . LEU D 2 442 ? 92.446  34.238  126.805 1.00 32.07  ? 442  LEU B N     1 
ATOM   10609 C  CA    . LEU D 2 442 ? 91.166  33.651  126.486 1.00 40.08  ? 442  LEU B CA    1 
ATOM   10610 C  C     . LEU D 2 442 ? 90.382  34.552  125.504 1.00 41.45  ? 442  LEU B C     1 
ATOM   10611 O  O     . LEU D 2 442 ? 89.260  34.218  125.126 1.00 43.94  ? 442  LEU B O     1 
ATOM   10612 C  CB    . LEU D 2 442 ? 90.385  33.439  127.779 1.00 34.80  ? 442  LEU B CB    1 
ATOM   10613 C  CG    . LEU D 2 442 ? 90.180  32.027  128.320 1.00 37.17  ? 442  LEU B CG    1 
ATOM   10614 C  CD1   . LEU D 2 442 ? 91.310  31.070  127.936 1.00 27.31  ? 442  LEU B CD1   1 
ATOM   10615 C  CD2   . LEU D 2 442 ? 90.031  32.161  129.827 1.00 33.46  ? 442  LEU B CD2   1 
ATOM   10616 N  N     . GLU D 2 443 ? 90.980  35.676  125.092 1.00 37.47  ? 443  GLU B N     1 
ATOM   10617 C  CA    . GLU D 2 443 ? 90.353  36.626  124.136 1.00 44.04  ? 443  GLU B CA    1 
ATOM   10618 C  C     . GLU D 2 443 ? 91.280  36.615  122.921 1.00 43.38  ? 443  GLU B C     1 
ATOM   10619 O  O     . GLU D 2 443 ? 92.241  37.388  122.847 1.00 35.63  ? 443  GLU B O     1 
ATOM   10620 C  CB    . GLU D 2 443 ? 90.278  38.026  124.753 1.00 39.03  ? 443  GLU B CB    1 
ATOM   10621 C  CG    . GLU D 2 443 ? 89.510  38.060  126.071 1.00 42.44  ? 443  GLU B CG    1 
ATOM   10622 C  CD    . GLU D 2 443 ? 89.566  39.407  126.772 1.00 64.04  ? 443  GLU B CD    1 
ATOM   10623 O  OE1   . GLU D 2 443 ? 88.565  39.745  127.444 1.00 78.33  ? 443  GLU B OE1   1 
ATOM   10624 O  OE2   . GLU D 2 443 ? 90.595  40.123  126.676 1.00 55.93  ? 443  GLU B OE2   1 
ATOM   10625 N  N     . THR D 2 444 ? 90.952  35.757  121.957 1.00 35.65  ? 444  THR B N     1 
ATOM   10626 C  CA    . THR D 2 444 ? 91.821  35.509  120.804 1.00 37.89  ? 444  THR B CA    1 
ATOM   10627 C  C     . THR D 2 444 ? 91.098  35.242  119.463 1.00 34.65  ? 444  THR B C     1 
ATOM   10628 O  O     . THR D 2 444 ? 89.880  35.155  119.415 1.00 29.58  ? 444  THR B O     1 
ATOM   10629 C  CB    . THR D 2 444 ? 92.655  34.238  121.185 1.00 28.66  ? 444  THR B CB    1 
ATOM   10630 O  OG1   . THR D 2 444 ? 93.982  34.599  121.523 1.00 32.92  ? 444  THR B OG1   1 
ATOM   10631 C  CG2   . THR D 2 444 ? 92.612  33.201  120.122 1.00 16.73  ? 444  THR B CG2   1 
ATOM   10632 N  N     . PRO D 2 445 ? 91.853  35.148  118.351 1.00 28.31  ? 445  PRO B N     1 
ATOM   10633 C  CA    . PRO D 2 445 ? 91.101  34.859  117.121 1.00 29.73  ? 445  PRO B CA    1 
ATOM   10634 C  C     . PRO D 2 445 ? 90.742  33.364  117.126 1.00 24.58  ? 445  PRO B C     1 
ATOM   10635 O  O     . PRO D 2 445 ? 90.899  32.694  118.155 1.00 18.70  ? 445  PRO B O     1 
ATOM   10636 C  CB    . PRO D 2 445 ? 92.044  35.274  115.985 1.00 24.18  ? 445  PRO B CB    1 
ATOM   10637 C  CG    . PRO D 2 445 ? 93.339  35.581  116.647 1.00 38.91  ? 445  PRO B CG    1 
ATOM   10638 C  CD    . PRO D 2 445 ? 93.090  35.882  118.074 1.00 26.51  ? 445  PRO B CD    1 
ATOM   10639 N  N     . GLY D 2 446 ? 90.241  32.855  116.002 1.00 28.50  ? 446  GLY B N     1 
ATOM   10640 C  CA    . GLY D 2 446 ? 89.830  31.459  115.905 1.00 20.36  ? 446  GLY B CA    1 
ATOM   10641 C  C     . GLY D 2 446 ? 90.870  30.446  116.349 1.00 34.23  ? 446  GLY B C     1 
ATOM   10642 O  O     . GLY D 2 446 ? 92.066  30.589  116.061 1.00 24.89  ? 446  GLY B O     1 
ATOM   10643 N  N     . LEU D 2 447 ? 90.418  29.407  117.042 1.00 30.13  ? 447  LEU B N     1 
ATOM   10644 C  CA    . LEU D 2 447 ? 91.337  28.388  117.526 1.00 35.12  ? 447  LEU B CA    1 
ATOM   10645 C  C     . LEU D 2 447 ? 92.116  27.666  116.427 1.00 31.83  ? 447  LEU B C     1 
ATOM   10646 O  O     . LEU D 2 447 ? 93.334  27.542  116.507 1.00 30.74  ? 447  LEU B O     1 
ATOM   10647 C  CB    . LEU D 2 447 ? 90.602  27.351  118.383 1.00 34.71  ? 447  LEU B CB    1 
ATOM   10648 C  CG    . LEU D 2 447 ? 91.602  26.327  118.934 1.00 31.75  ? 447  LEU B CG    1 
ATOM   10649 C  CD1   . LEU D 2 447 ? 92.645  27.064  119.764 1.00 30.28  ? 447  LEU B CD1   1 
ATOM   10650 C  CD2   . LEU D 2 447 ? 90.906  25.270  119.772 1.00 33.07  ? 447  LEU B CD2   1 
ATOM   10651 N  N     . PHE D 2 448 ? 91.409  27.200  115.405 1.00 30.47  ? 448  PHE B N     1 
ATOM   10652 C  CA    . PHE D 2 448 ? 92.026  26.466  114.304 1.00 29.48  ? 448  PHE B CA    1 
ATOM   10653 C  C     . PHE D 2 448 ? 92.994  27.304  113.463 1.00 28.95  ? 448  PHE B C     1 
ATOM   10654 O  O     . PHE D 2 448 ? 93.998  26.792  112.999 1.00 28.13  ? 448  PHE B O     1 
ATOM   10655 C  CB    . PHE D 2 448 ? 90.917  25.847  113.446 1.00 24.38  ? 448  PHE B CB    1 
ATOM   10656 C  CG    . PHE D 2 448 ? 89.811  25.226  114.277 1.00 35.16  ? 448  PHE B CG    1 
ATOM   10657 C  CD1   . PHE D 2 448 ? 90.092  24.208  115.179 1.00 35.03  ? 448  PHE B CD1   1 
ATOM   10658 C  CD2   . PHE D 2 448 ? 88.508  25.706  114.202 1.00 39.32  ? 448  PHE B CD2   1 
ATOM   10659 C  CE1   . PHE D 2 448 ? 89.096  23.679  115.995 1.00 38.03  ? 448  PHE B CE1   1 
ATOM   10660 C  CE2   . PHE D 2 448 ? 87.511  25.189  115.009 1.00 38.22  ? 448  PHE B CE2   1 
ATOM   10661 C  CZ    . PHE D 2 448 ? 87.806  24.171  115.910 1.00 33.63  ? 448  PHE B CZ    1 
ATOM   10662 N  N     . GLU D 2 449 ? 92.731  28.587  113.277 1.00 26.13  ? 449  GLU B N     1 
ATOM   10663 C  CA    . GLU D 2 449 ? 93.685  29.355  112.497 1.00 38.03  ? 449  GLU B CA    1 
ATOM   10664 C  C     . GLU D 2 449 ? 94.884  29.699  113.374 1.00 32.28  ? 449  GLU B C     1 
ATOM   10665 O  O     . GLU D 2 449 ? 96.012  29.821  112.896 1.00 28.88  ? 449  GLU B O     1 
ATOM   10666 C  CB    . GLU D 2 449 ? 93.049  30.625  111.917 1.00 40.96  ? 449  GLU B CB    1 
ATOM   10667 C  CG    . GLU D 2 449 ? 92.003  31.282  112.788 1.00 57.20  ? 449  GLU B CG    1 
ATOM   10668 C  CD    . GLU D 2 449 ? 90.594  30.789  112.494 1.00 59.78  ? 449  GLU B CD    1 
ATOM   10669 O  OE1   . GLU D 2 449 ? 90.092  29.866  113.207 1.00 48.29  ? 449  GLU B OE1   1 
ATOM   10670 O  OE2   . GLU D 2 449 ? 90.003  31.343  111.537 1.00 55.51  ? 449  GLU B OE2   1 
ATOM   10671 N  N     . ILE D 2 450 ? 94.626  29.840  114.666 1.00 32.82  ? 450  ILE B N     1 
ATOM   10672 C  CA    . ILE D 2 450 ? 95.662  30.153  115.644 1.00 28.89  ? 450  ILE B CA    1 
ATOM   10673 C  C     . ILE D 2 450 ? 96.538  28.901  115.837 1.00 37.48  ? 450  ILE B C     1 
ATOM   10674 O  O     . ILE D 2 450 ? 97.745  28.988  115.986 1.00 34.22  ? 450  ILE B O     1 
ATOM   10675 C  CB    . ILE D 2 450 ? 94.978  30.607  116.961 1.00 33.93  ? 450  ILE B CB    1 
ATOM   10676 C  CG1   . ILE D 2 450 ? 94.713  32.100  116.885 1.00 30.53  ? 450  ILE B CG1   1 
ATOM   10677 C  CG2   . ILE D 2 450 ? 95.781  30.249  118.170 1.00 33.01  ? 450  ILE B CG2   1 
ATOM   10678 C  CD1   . ILE D 2 450 ? 95.966  32.874  116.668 1.00 51.85  ? 450  ILE B CD1   1 
ATOM   10679 N  N     . LEU D 2 451 ? 95.923  27.726  115.803 1.00 34.99  ? 451  LEU B N     1 
ATOM   10680 C  CA    . LEU D 2 451 ? 96.670  26.503  115.975 1.00 33.97  ? 451  LEU B CA    1 
ATOM   10681 C  C     . LEU D 2 451 ? 97.450  26.214  114.687 1.00 35.27  ? 451  LEU B C     1 
ATOM   10682 O  O     . LEU D 2 451 ? 98.570  25.723  114.723 1.00 37.24  ? 451  LEU B O     1 
ATOM   10683 C  CB    . LEU D 2 451 ? 95.698  25.371  116.320 1.00 31.47  ? 451  LEU B CB    1 
ATOM   10684 C  CG    . LEU D 2 451 ? 96.209  23.959  116.618 1.00 39.23  ? 451  LEU B CG    1 
ATOM   10685 C  CD1   . LEU D 2 451 ? 97.062  23.951  117.855 1.00 36.74  ? 451  LEU B CD1   1 
ATOM   10686 C  CD2   . LEU D 2 451 ? 95.026  23.047  116.817 1.00 37.36  ? 451  LEU B CD2   1 
ATOM   10687 N  N     . ALA D 2 452 ? 96.870  26.564  113.548 1.00 31.95  ? 452  ALA B N     1 
ATOM   10688 C  CA    . ALA D 2 452 ? 97.522  26.313  112.273 1.00 29.45  ? 452  ALA B CA    1 
ATOM   10689 C  C     . ALA D 2 452 ? 98.608  27.328  111.858 1.00 35.05  ? 452  ALA B C     1 
ATOM   10690 O  O     . ALA D 2 452 ? 99.566  26.957  111.175 1.00 33.64  ? 452  ALA B O     1 
ATOM   10691 C  CB    . ALA D 2 452 ? 96.456  26.196  111.171 1.00 25.91  ? 452  ALA B CB    1 
ATOM   10692 N  N     . LEU D 2 453 ? 98.483  28.583  112.286 1.00 29.35  ? 453  LEU B N     1 
ATOM   10693 C  CA    . LEU D 2 453 ? 99.438  29.628  111.910 1.00 37.69  ? 453  LEU B CA    1 
ATOM   10694 C  C     . LEU D 2 453 ? 100.933 29.367  112.169 1.00 40.31  ? 453  LEU B C     1 
ATOM   10695 O  O     . LEU D 2 453 ? 101.767 29.639  111.316 1.00 33.30  ? 453  LEU B O     1 
ATOM   10696 C  CB    . LEU D 2 453 ? 99.048  30.975  112.557 1.00 32.44  ? 453  LEU B CB    1 
ATOM   10697 C  CG    . LEU D 2 453 ? 100.034 32.135  112.318 1.00 37.54  ? 453  LEU B CG    1 
ATOM   10698 C  CD1   . LEU D 2 453 ? 100.429 32.169  110.847 1.00 26.03  ? 453  LEU B CD1   1 
ATOM   10699 C  CD2   . LEU D 2 453 ? 99.423  33.468  112.741 1.00 27.23  ? 453  LEU B CD2   1 
ATOM   10700 N  N     . LEU D 2 454 ? 101.281 28.840  113.333 1.00 41.89  ? 454  LEU B N     1 
ATOM   10701 C  CA    . LEU D 2 454 ? 102.693 28.611  113.612 1.00 43.28  ? 454  LEU B CA    1 
ATOM   10702 C  C     . LEU D 2 454 ? 103.285 27.314  113.085 1.00 38.39  ? 454  LEU B C     1 
ATOM   10703 O  O     . LEU D 2 454 ? 104.496 27.164  113.046 1.00 45.09  ? 454  LEU B O     1 
ATOM   10704 C  CB    . LEU D 2 454 ? 102.946 28.700  115.110 1.00 49.29  ? 454  LEU B CB    1 
ATOM   10705 C  CG    . LEU D 2 454 ? 101.697 28.648  115.974 1.00 47.57  ? 454  LEU B CG    1 
ATOM   10706 C  CD1   . LEU D 2 454 ? 100.967 29.986  115.871 1.00 60.09  ? 454  LEU B CD1   1 
ATOM   10707 C  CD2   . LEU D 2 454 ? 100.826 27.491  115.542 1.00 48.94  ? 454  LEU B CD2   1 
ATOM   10708 N  N     . GLY D 2 455 ? 102.448 26.378  112.667 1.00 33.90  ? 455  GLY B N     1 
ATOM   10709 C  CA    . GLY D 2 455 ? 102.985 25.118  112.188 1.00 24.74  ? 455  GLY B CA    1 
ATOM   10710 C  C     . GLY D 2 455 ? 103.001 24.109  113.309 1.00 24.41  ? 455  GLY B C     1 
ATOM   10711 O  O     . GLY D 2 455 ? 103.001 24.467  114.493 1.00 31.78  ? 455  GLY B O     1 
ATOM   10712 N  N     . LYS D 2 456 ? 103.035 22.837  112.957 1.00 23.34  ? 456  LYS B N     1 
ATOM   10713 C  CA    . LYS D 2 456 ? 103.027 21.784  113.970 1.00 28.29  ? 456  LYS B CA    1 
ATOM   10714 C  C     . LYS D 2 456 ? 104.070 21.898  115.107 1.00 30.15  ? 456  LYS B C     1 
ATOM   10715 O  O     . LYS D 2 456 ? 103.715 21.977  116.285 1.00 29.92  ? 456  LYS B O     1 
ATOM   10716 C  CB    . LYS D 2 456 ? 103.182 20.416  113.286 1.00 23.59  ? 456  LYS B CB    1 
ATOM   10717 C  CG    . LYS D 2 456 ? 102.979 19.222  114.220 1.00 24.95  ? 456  LYS B CG    1 
ATOM   10718 C  CD    . LYS D 2 456 ? 103.035 17.932  113.441 1.00 20.59  ? 456  LYS B CD    1 
ATOM   10719 C  CE    . LYS D 2 456 ? 103.045 16.728  114.354 1.00 28.45  ? 456  LYS B CE    1 
ATOM   10720 N  NZ    . LYS D 2 456 ? 103.113 15.469  113.594 1.00 25.80  ? 456  LYS B NZ    1 
ATOM   10721 N  N     . GLU D 2 457 ? 105.350 21.897  114.755 1.00 28.28  ? 457  GLU B N     1 
ATOM   10722 C  CA    . GLU D 2 457 ? 106.394 21.931  115.771 1.00 28.28  ? 457  GLU B CA    1 
ATOM   10723 C  C     . GLU D 2 457 ? 106.312 23.087  116.757 1.00 27.46  ? 457  GLU B C     1 
ATOM   10724 O  O     . GLU D 2 457 ? 106.417 22.902  117.970 1.00 31.87  ? 457  GLU B O     1 
ATOM   10725 C  CB    . GLU D 2 457 ? 107.770 21.897  115.098 1.00 27.86  ? 457  GLU B CB    1 
ATOM   10726 C  CG    . GLU D 2 457 ? 108.015 20.611  114.277 1.00 27.18  ? 457  GLU B CG    1 
ATOM   10727 C  CD    . GLU D 2 457 ? 107.778 19.347  115.082 1.00 39.07  ? 457  GLU B CD    1 
ATOM   10728 O  OE1   . GLU D 2 457 ? 108.215 19.293  116.251 1.00 55.01  ? 457  GLU B OE1   1 
ATOM   10729 O  OE2   . GLU D 2 457 ? 107.161 18.397  114.558 1.00 50.36  ? 457  GLU B OE2   1 
ATOM   10730 N  N     . ARG D 2 458 ? 106.111 24.284  116.244 1.00 27.47  ? 458  ARG B N     1 
ATOM   10731 C  CA    . ARG D 2 458 ? 106.048 25.453  117.093 1.00 32.44  ? 458  ARG B CA    1 
ATOM   10732 C  C     . ARG D 2 458 ? 104.841 25.367  118.019 1.00 32.00  ? 458  ARG B C     1 
ATOM   10733 O  O     . ARG D 2 458 ? 104.920 25.791  119.172 1.00 31.68  ? 458  ARG B O     1 
ATOM   10734 C  CB    . ARG D 2 458 ? 105.997 26.709  116.220 1.00 32.49  ? 458  ARG B CB    1 
ATOM   10735 C  CG    . ARG D 2 458 ? 106.250 28.004  116.961 1.00 42.92  ? 458  ARG B CG    1 
ATOM   10736 C  CD    . ARG D 2 458 ? 106.290 29.157  115.988 1.00 43.09  ? 458  ARG B CD    1 
ATOM   10737 N  NE    . ARG D 2 458 ? 107.260 28.906  114.931 1.00 37.64  ? 458  ARG B NE    1 
ATOM   10738 C  CZ    . ARG D 2 458 ? 107.249 29.501  113.746 1.00 42.18  ? 458  ARG B CZ    1 
ATOM   10739 N  NH1   . ARG D 2 458 ? 106.294 30.386  113.452 1.00 43.32  ? 458  ARG B NH1   1 
ATOM   10740 N  NH2   . ARG D 2 458 ? 108.223 29.247  112.873 1.00 32.82  ? 458  ARG B NH2   1 
ATOM   10741 N  N     . ALA D 2 459 ? 103.728 24.819  117.525 1.00 27.96  ? 459  ALA B N     1 
ATOM   10742 C  CA    . ALA D 2 459 ? 102.550 24.675  118.378 1.00 29.47  ? 459  ALA B CA    1 
ATOM   10743 C  C     . ALA D 2 459 ? 102.851 23.683  119.516 1.00 35.04  ? 459  ALA B C     1 
ATOM   10744 O  O     . ALA D 2 459 ? 102.593 23.967  120.678 1.00 33.25  ? 459  ALA B O     1 
ATOM   10745 C  CB    . ALA D 2 459 ? 101.377 24.187  117.573 1.00 33.26  ? 459  ALA B CB    1 
ATOM   10746 N  N     . LEU D 2 460 ? 103.403 22.517  119.176 1.00 34.87  ? 460  LEU B N     1 
ATOM   10747 C  CA    . LEU D 2 460 ? 103.724 21.506  120.178 1.00 29.72  ? 460  LEU B CA    1 
ATOM   10748 C  C     . LEU D 2 460 ? 104.673 22.024  121.249 1.00 31.14  ? 460  LEU B C     1 
ATOM   10749 O  O     . LEU D 2 460 ? 104.470 21.760  122.422 1.00 32.30  ? 460  LEU B O     1 
ATOM   10750 C  CB    . LEU D 2 460 ? 104.344 20.279  119.515 1.00 31.95  ? 460  LEU B CB    1 
ATOM   10751 C  CG    . LEU D 2 460 ? 103.444 19.562  118.503 1.00 40.19  ? 460  LEU B CG    1 
ATOM   10752 C  CD1   . LEU D 2 460 ? 104.200 18.408  117.862 1.00 34.35  ? 460  LEU B CD1   1 
ATOM   10753 C  CD2   . LEU D 2 460 ? 102.190 19.048  119.188 1.00 33.92  ? 460  LEU B CD2   1 
ATOM   10754 N  N     . ARG D 2 461 ? 105.716 22.755  120.853 1.00 30.65  ? 461  ARG B N     1 
ATOM   10755 C  CA    . ARG D 2 461 ? 106.660 23.288  121.830 1.00 25.61  ? 461  ARG B CA    1 
ATOM   10756 C  C     . ARG D 2 461 ? 105.927 24.120  122.869 1.00 31.20  ? 461  ARG B C     1 
ATOM   10757 O  O     . ARG D 2 461 ? 106.167 23.971  124.063 1.00 31.39  ? 461  ARG B O     1 
ATOM   10758 C  CB    . ARG D 2 461 ? 107.742 24.140  121.164 1.00 24.41  ? 461  ARG B CB    1 
ATOM   10759 C  CG    . ARG D 2 461 ? 108.684 23.382  120.209 1.00 26.22  ? 461  ARG B CG    1 
ATOM   10760 C  CD    . ARG D 2 461 ? 109.401 22.177  120.884 1.00 17.90  ? 461  ARG B CD    1 
ATOM   10761 N  NE    . ARG D 2 461 ? 108.678 20.899  120.751 1.00 18.63  ? 461  ARG B NE    1 
ATOM   10762 C  CZ    . ARG D 2 461 ? 108.553 20.182  119.630 1.00 20.02  ? 461  ARG B CZ    1 
ATOM   10763 N  NH1   . ARG D 2 461 ? 109.086 20.592  118.480 1.00 20.83  ? 461  ARG B NH1   1 
ATOM   10764 N  NH2   . ARG D 2 461 ? 107.936 19.010  119.669 1.00 17.87  ? 461  ARG B NH2   1 
ATOM   10765 N  N     . ARG D 2 462 ? 105.026 24.994  122.434 1.00 34.12  ? 462  ARG B N     1 
ATOM   10766 C  CA    . ARG D 2 462 ? 104.261 25.795  123.402 1.00 38.97  ? 462  ARG B CA    1 
ATOM   10767 C  C     . ARG D 2 462 ? 103.364 24.922  124.254 1.00 34.88  ? 462  ARG B C     1 
ATOM   10768 O  O     . ARG D 2 462 ? 103.280 25.113  125.463 1.00 38.60  ? 462  ARG B O     1 
ATOM   10769 C  CB    . ARG D 2 462 ? 103.367 26.825  122.716 1.00 38.30  ? 462  ARG B CB    1 
ATOM   10770 C  CG    . ARG D 2 462 ? 104.116 27.969  122.181 1.00 38.57  ? 462  ARG B CG    1 
ATOM   10771 C  CD    . ARG D 2 462 ? 103.278 29.201  122.145 1.00 34.86  ? 462  ARG B CD    1 
ATOM   10772 N  NE    . ARG D 2 462 ? 104.147 30.277  121.714 1.00 31.41  ? 462  ARG B NE    1 
ATOM   10773 C  CZ    . ARG D 2 462 ? 103.742 31.493  121.395 1.00 34.93  ? 462  ARG B CZ    1 
ATOM   10774 N  NH1   . ARG D 2 462 ? 102.455 31.792  121.469 1.00 33.17  ? 462  ARG B NH1   1 
ATOM   10775 N  NH2   . ARG D 2 462 ? 104.630 32.396  120.973 1.00 32.63  ? 462  ARG B NH2   1 
ATOM   10776 N  N     . LEU D 2 463 ? 102.669 23.994  123.603 1.00 26.11  ? 463  LEU B N     1 
ATOM   10777 C  CA    . LEU D 2 463 ? 101.772 23.092  124.287 1.00 33.47  ? 463  LEU B CA    1 
ATOM   10778 C  C     . LEU D 2 463 ? 102.560 22.303  125.324 1.00 38.60  ? 463  LEU B C     1 
ATOM   10779 O  O     . LEU D 2 463 ? 102.067 22.054  126.417 1.00 44.14  ? 463  LEU B O     1 
ATOM   10780 C  CB    . LEU D 2 463 ? 101.133 22.125  123.300 1.00 36.36  ? 463  LEU B CB    1 
ATOM   10781 C  CG    . LEU D 2 463 ? 99.671  21.750  123.573 1.00 49.68  ? 463  LEU B CG    1 
ATOM   10782 C  CD1   . LEU D 2 463 ? 99.379  20.388  122.968 1.00 37.98  ? 463  LEU B CD1   1 
ATOM   10783 C  CD2   . LEU D 2 463 ? 99.398  21.711  125.071 1.00 40.43  ? 463  LEU B CD2   1 
ATOM   10784 N  N     . GLU D 2 464 ? 103.788 21.912  124.993 1.00 39.43  ? 464  GLU B N     1 
ATOM   10785 C  CA    . GLU D 2 464 ? 104.607 21.160  125.948 1.00 40.56  ? 464  GLU B CA    1 
ATOM   10786 C  C     . GLU D 2 464 ? 104.968 22.002  127.156 1.00 39.08  ? 464  GLU B C     1 
ATOM   10787 O  O     . GLU D 2 464 ? 104.889 21.521  128.281 1.00 41.68  ? 464  GLU B O     1 
ATOM   10788 C  CB    . GLU D 2 464 ? 105.883 20.616  125.296 1.00 37.25  ? 464  GLU B CB    1 
ATOM   10789 C  CG    . GLU D 2 464 ? 105.635 19.461  124.322 1.00 43.29  ? 464  GLU B CG    1 
ATOM   10790 C  CD    . GLU D 2 464 ? 106.726 19.305  123.258 1.00 42.07  ? 464  GLU B CD    1 
ATOM   10791 O  OE1   . GLU D 2 464 ? 106.478 18.555  122.305 1.00 43.19  ? 464  GLU B OE1   1 
ATOM   10792 O  OE2   . GLU D 2 464 ? 107.817 19.917  123.359 1.00 38.98  ? 464  GLU B OE2   1 
ATOM   10793 N  N     . ARG D 2 465 ? 105.375 23.247  126.934 1.00 38.12  ? 465  ARG B N     1 
ATOM   10794 C  CA    . ARG D 2 465 ? 105.715 24.139  128.043 1.00 41.87  ? 465  ARG B CA    1 
ATOM   10795 C  C     . ARG D 2 465 ? 104.548 24.298  129.021 1.00 47.23  ? 465  ARG B C     1 
ATOM   10796 O  O     . ARG D 2 465 ? 104.746 24.415  130.224 1.00 50.51  ? 465  ARG B O     1 
ATOM   10797 C  CB    . ARG D 2 465 ? 106.078 25.531  127.536 1.00 40.79  ? 465  ARG B CB    1 
ATOM   10798 C  CG    . ARG D 2 465 ? 107.555 25.806  127.494 1.00 58.37  ? 465  ARG B CG    1 
ATOM   10799 C  CD    . ARG D 2 465 ? 107.884 27.206  128.007 1.00 63.17  ? 465  ARG B CD    1 
ATOM   10800 N  NE    . ARG D 2 465 ? 107.819 28.253  126.989 1.00 66.03  ? 465  ARG B NE    1 
ATOM   10801 C  CZ    . ARG D 2 465 ? 106.693 28.768  126.500 1.00 74.70  ? 465  ARG B CZ    1 
ATOM   10802 N  NH1   . ARG D 2 465 ? 105.519 28.326  126.939 1.00 73.85  ? 465  ARG B NH1   1 
ATOM   10803 N  NH2   . ARG D 2 465 ? 106.741 29.737  125.583 1.00 59.92  ? 465  ARG B NH2   1 
ATOM   10804 N  N     . ALA D 2 466 ? 103.329 24.306  128.499 1.00 45.49  ? 466  ALA B N     1 
ATOM   10805 C  CA    . ALA D 2 466 ? 102.165 24.490  129.339 1.00 47.94  ? 466  ALA B CA    1 
ATOM   10806 C  C     . ALA D 2 466 ? 101.781 23.235  130.084 1.00 51.68  ? 466  ALA B C     1 
ATOM   10807 O  O     . ALA D 2 466 ? 101.173 23.305  131.143 1.00 57.17  ? 466  ALA B O     1 
ATOM   10808 C  CB    . ALA D 2 466 ? 101.005 24.972  128.502 1.00 50.83  ? 466  ALA B CB    1 
ATOM   10809 N  N     . LEU D 2 467 ? 102.123 22.083  129.527 1.00 53.64  ? 467  LEU B N     1 
ATOM   10810 C  CA    . LEU D 2 467 ? 101.790 20.823  130.169 1.00 54.30  ? 467  LEU B CA    1 
ATOM   10811 C  C     . LEU D 2 467 ? 102.925 20.369  131.076 1.00 61.87  ? 467  LEU B C     1 
ATOM   10812 O  O     . LEU D 2 467 ? 102.777 19.411  131.837 1.00 70.60  ? 467  LEU B O     1 
ATOM   10813 C  CB    . LEU D 2 467 ? 101.518 19.755  129.111 1.00 50.63  ? 467  LEU B CB    1 
ATOM   10814 C  CG    . LEU D 2 467 ? 100.327 20.010  128.192 1.00 51.95  ? 467  LEU B CG    1 
ATOM   10815 C  CD1   . LEU D 2 467 ? 100.187 18.875  127.184 1.00 52.05  ? 467  LEU B CD1   1 
ATOM   10816 C  CD2   . LEU D 2 467 ? 99.071  20.144  129.031 1.00 52.55  ? 467  LEU B CD2   1 
ATOM   10817 N  N     . ALA D 2 468 ? 104.054 21.065  130.999 1.00 65.72  ? 468  ALA B N     1 
ATOM   10818 C  CA    . ALA D 2 468 ? 105.230 20.720  131.791 1.00 67.53  ? 468  ALA B CA    1 
ATOM   10819 C  C     . ALA D 2 468 ? 105.025 20.989  133.263 1.00 70.21  ? 468  ALA B C     1 
ATOM   10820 O  O     . ALA D 2 468 ? 105.430 20.113  134.049 1.00 69.71  ? 468  ALA B O     1 
ATOM   10821 C  CB    . ALA D 2 468 ? 106.449 21.487  131.291 1.00 72.78  ? 468  ALA B CB    1 
ATOM   10822 O  OXT   . ALA D 2 468 ? 104.490 22.069  133.607 1.00 73.67  ? 468  ALA B OXT   1 
HETATM 10823 MG MG    . MG  E 3 .   ? 5.930   59.017  56.378  1.00 40.87  ? 901  MG  C MG    1 
HETATM 10824 MG MG    . MG  F 3 .   ? 64.830  58.926  121.833 1.00 58.02  ? 902  MG  D MG    1 
HETATM 10825 N  N     . GLU G 4 .   ? 40.840  82.444  52.682  1.00 24.12  ? 601  GLU A N     1 
HETATM 10826 C  CA    . GLU G 4 .   ? 39.370  82.364  52.688  1.00 44.05  ? 601  GLU A CA    1 
HETATM 10827 C  C     . GLU G 4 .   ? 38.987  81.056  53.371  1.00 47.21  ? 601  GLU A C     1 
HETATM 10828 O  O     . GLU G 4 .   ? 38.916  81.053  54.617  1.00 61.64  ? 601  GLU A O     1 
HETATM 10829 C  CB    . GLU G 4 .   ? 38.833  82.413  51.243  1.00 36.99  ? 601  GLU A CB    1 
HETATM 10830 C  CG    . GLU G 4 .   ? 37.309  82.383  51.127  1.00 19.44  ? 601  GLU A CG    1 
HETATM 10831 C  CD    . GLU G 4 .   ? 36.812  82.983  49.820  1.00 34.14  ? 601  GLU A CD    1 
HETATM 10832 O  OE1   . GLU G 4 .   ? 36.658  84.233  49.695  1.00 21.87  ? 601  GLU A OE1   1 
HETATM 10833 O  OE2   . GLU G 4 .   ? 36.595  82.188  48.898  1.00 31.97  ? 601  GLU A OE2   1 
HETATM 10834 O  OXT   . GLU G 4 .   ? 38.769  80.056  52.665  1.00 47.00  ? 601  GLU A OXT   1 
HETATM 10835 N  N     . GLU H 4 .   ? 97.980  83.427  112.706 1.00 50.04  ? 602  GLU A N     1 
HETATM 10836 C  CA    . GLU H 4 .   ? 96.556  83.320  113.141 1.00 50.23  ? 602  GLU A CA    1 
HETATM 10837 C  C     . GLU H 4 .   ? 96.300  81.938  113.762 1.00 52.18  ? 602  GLU A C     1 
HETATM 10838 O  O     . GLU H 4 .   ? 97.038  81.582  114.700 1.00 63.21  ? 602  GLU A O     1 
HETATM 10839 C  CB    . GLU H 4 .   ? 95.645  83.550  111.933 1.00 45.15  ? 602  GLU A CB    1 
HETATM 10840 C  CG    . GLU H 4 .   ? 94.210  83.803  112.278 1.00 43.37  ? 602  GLU A CG    1 
HETATM 10841 C  CD    . GLU H 4 .   ? 93.384  84.107  111.055 1.00 54.31  ? 602  GLU A CD    1 
HETATM 10842 O  OE1   . GLU H 4 .   ? 93.269  85.296  110.697 1.00 45.46  ? 602  GLU A OE1   1 
HETATM 10843 O  OE2   . GLU H 4 .   ? 92.862  83.150  110.442 1.00 54.05  ? 602  GLU A OE2   1 
HETATM 10844 O  OXT   . GLU H 4 .   ? 95.383  81.218  113.323 1.00 57.66  ? 602  GLU A OXT   1 
HETATM 10845 O  O     . HOH I 5 .   ? 20.295  77.107  57.936  1.00 44.75  ? 1006 HOH C O     1 
HETATM 10846 O  O     . HOH I 5 .   ? 16.336  70.176  43.824  1.00 45.98  ? 1039 HOH C O     1 
HETATM 10847 O  O     . HOH I 5 .   ? 17.253  91.689  61.693  1.00 37.95  ? 1055 HOH C O     1 
HETATM 10848 O  O     . HOH I 5 .   ? 38.413  97.773  63.626  1.00 39.92  ? 1065 HOH C O     1 
HETATM 10849 O  O     . HOH I 5 .   ? 3.175   58.632  57.888  1.00 41.91  ? 1075 HOH C O     1 
HETATM 10850 O  O     . HOH I 5 .   ? 14.172  64.489  56.436  1.00 31.91  ? 1077 HOH C O     1 
HETATM 10851 O  O     . HOH I 5 .   ? 4.402   80.302  67.431  1.00 49.40  ? 1082 HOH C O     1 
HETATM 10852 O  O     . HOH I 5 .   ? 13.689  66.075  41.299  1.00 46.42  ? 1090 HOH C O     1 
HETATM 10853 O  O     . HOH I 5 .   ? 43.764  85.964  53.571  1.00 33.86  ? 1098 HOH C O     1 
HETATM 10854 O  O     . HOH I 5 .   ? 18.121  67.584  55.133  1.00 33.33  ? 1114 HOH C O     1 
HETATM 10855 O  O     . HOH I 5 .   ? 18.598  44.509  54.903  1.00 49.39  ? 1116 HOH C O     1 
HETATM 10856 O  O     . HOH I 5 .   ? 33.249  83.807  60.312  1.00 39.85  ? 1121 HOH C O     1 
HETATM 10857 O  O     . HOH I 5 .   ? 27.547  84.703  68.421  1.00 44.16  ? 1123 HOH C O     1 
HETATM 10858 O  O     . HOH I 5 .   ? -3.080  62.375  53.426  1.00 40.80  ? 1130 HOH C O     1 
HETATM 10859 O  O     . HOH I 5 .   ? 8.250   58.117  52.412  1.00 37.25  ? 1132 HOH C O     1 
HETATM 10860 O  O     . HOH I 5 .   ? 13.869  55.692  55.142  1.00 35.81  ? 1137 HOH C O     1 
HETATM 10861 O  O     . HOH I 5 .   ? 2.658   58.231  47.343  1.00 48.66  ? 1147 HOH C O     1 
HETATM 10862 O  O     . HOH I 5 .   ? -5.129  63.551  47.581  1.00 46.68  ? 1149 HOH C O     1 
HETATM 10863 O  O     . HOH I 5 .   ? 4.972   58.135  54.070  1.00 40.17  ? 1150 HOH C O     1 
HETATM 10864 O  O     . HOH I 5 .   ? 12.861  70.332  48.733  1.00 48.29  ? 1153 HOH C O     1 
HETATM 10865 O  O     . HOH I 5 .   ? 7.423   55.016  53.261  1.00 26.68  ? 1178 HOH C O     1 
HETATM 10866 O  O     . HOH I 5 .   ? 36.271  91.686  68.447  1.00 44.25  ? 1184 HOH C O     1 
HETATM 10867 O  O     . HOH I 5 .   ? 6.107   69.788  37.686  1.00 39.98  ? 1186 HOH C O     1 
HETATM 10868 O  O     . HOH I 5 .   ? 8.174   71.953  47.029  1.00 53.49  ? 1192 HOH C O     1 
HETATM 10869 O  O     . HOH I 5 .   ? -6.378  62.899  45.251  1.00 61.27  ? 1279 HOH C O     1 
HETATM 10870 O  O     . HOH I 5 .   ? 29.710  84.887  66.643  1.00 56.35  ? 1281 HOH C O     1 
HETATM 10871 O  O     . HOH J 5 .   ? 72.246  55.847  119.174 1.00 31.26  ? 1024 HOH D O     1 
HETATM 10872 O  O     . HOH J 5 .   ? 84.856  48.152  118.352 1.00 35.07  ? 1026 HOH D O     1 
HETATM 10873 O  O     . HOH J 5 .   ? 66.048  55.354  119.882 1.00 40.81  ? 1036 HOH D O     1 
HETATM 10874 O  O     . HOH J 5 .   ? 70.649  69.989  113.452 1.00 46.41  ? 1044 HOH D O     1 
HETATM 10875 O  O     . HOH J 5 .   ? 74.103  68.393  121.400 1.00 47.78  ? 1061 HOH D O     1 
HETATM 10876 O  O     . HOH J 5 .   ? 76.086  69.752  121.932 1.00 38.53  ? 1074 HOH D O     1 
HETATM 10877 O  O     . HOH J 5 .   ? 82.689  63.122  124.298 1.00 38.61  ? 1085 HOH D O     1 
HETATM 10878 O  O     . HOH J 5 .   ? 82.036  86.538  118.997 1.00 41.10  ? 1096 HOH D O     1 
HETATM 10879 O  O     . HOH J 5 .   ? 81.766  57.875  121.862 1.00 31.55  ? 1097 HOH D O     1 
HETATM 10880 O  O     . HOH J 5 .   ? 75.980  91.491  125.553 1.00 40.45  ? 1100 HOH D O     1 
HETATM 10881 O  O     . HOH J 5 .   ? 75.873  44.814  124.696 1.00 48.10  ? 1103 HOH D O     1 
HETATM 10882 O  O     . HOH J 5 .   ? 83.675  30.695  115.592 1.00 42.26  ? 1115 HOH D O     1 
HETATM 10883 O  O     . HOH J 5 .   ? 80.140  79.978  120.163 1.00 43.53  ? 1125 HOH D O     1 
HETATM 10884 O  O     . HOH J 5 .   ? 79.659  43.936  117.773 1.00 47.56  ? 1126 HOH D O     1 
HETATM 10885 O  O     . HOH J 5 .   ? 69.151  78.178  136.083 1.00 43.73  ? 1146 HOH D O     1 
HETATM 10886 O  O     . HOH J 5 .   ? 83.149  87.610  129.512 1.00 49.34  ? 1166 HOH D O     1 
HETATM 10887 O  O     . HOH J 5 .   ? 70.736  37.635  129.925 1.00 56.52  ? 1172 HOH D O     1 
HETATM 10888 O  O     . HOH J 5 .   ? 72.844  64.635  121.066 1.00 40.86  ? 1175 HOH D O     1 
HETATM 10889 O  O     . HOH J 5 .   ? 66.471  75.810  135.515 1.00 42.41  ? 1183 HOH D O     1 
HETATM 10890 O  O     . HOH J 5 .   ? 93.070  94.782  122.423 1.00 52.01  ? 1194 HOH D O     1 
HETATM 10891 O  O     . HOH J 5 .   ? 81.763  86.369  132.892 1.00 50.25  ? 1198 HOH D O     1 
HETATM 10892 O  O     . HOH J 5 .   ? 64.742  45.177  111.414 1.00 71.79  ? 1280 HOH D O     1 
HETATM 10893 O  O     . HOH J 5 .   ? 51.950  64.249  114.667 1.00 61.77  ? 1282 HOH D O     1 
HETATM 10894 O  O     . HOH J 5 .   ? 52.572  62.763  118.345 1.00 72.56  ? 1283 HOH D O     1 
HETATM 10895 O  O     . HOH J 5 .   ? 55.200  63.028  120.248 1.00 65.00  ? 1284 HOH D O     1 
HETATM 10896 O  O     . HOH J 5 .   ? 68.687  56.533  108.625 1.00 52.55  ? 1286 HOH D O     1 
HETATM 10897 O  O     . HOH J 5 .   ? 65.510  55.956  109.087 1.00 57.95  ? 1287 HOH D O     1 
HETATM 10898 O  O     . HOH J 5 .   ? 72.565  54.788  108.214 1.00 50.57  ? 1288 HOH D O     1 
HETATM 10899 O  O     . HOH J 5 .   ? 77.993  49.881  131.982 1.00 58.31  ? 1289 HOH D O     1 
HETATM 10900 O  O     . HOH K 5 .   ? 41.776  73.058  54.820  1.00 28.07  ? 1002 HOH A O     1 
HETATM 10901 O  O     . HOH K 5 .   ? 55.480  74.523  53.992  1.00 33.30  ? 1004 HOH A O     1 
HETATM 10902 O  O     . HOH K 5 .   ? 38.975  95.456  60.308  1.00 39.67  ? 1009 HOH A O     1 
HETATM 10903 O  O     . HOH K 5 .   ? 46.560  104.635 70.132  1.00 28.22  ? 1011 HOH A O     1 
HETATM 10904 O  O     . HOH K 5 .   ? 33.381  105.216 59.642  1.00 36.30  ? 1014 HOH A O     1 
HETATM 10905 O  O     . HOH K 5 .   ? 42.616  101.630 63.465  1.00 27.79  ? 1015 HOH A O     1 
HETATM 10906 O  O     . HOH K 5 .   ? 57.218  92.188  58.771  1.00 43.84  ? 1017 HOH A O     1 
HETATM 10907 O  O     . HOH K 5 .   ? 25.137  77.572  56.520  1.00 34.01  ? 1018 HOH A O     1 
HETATM 10908 O  O     . HOH K 5 .   ? 35.336  80.651  43.157  1.00 16.51  ? 1019 HOH A O     1 
HETATM 10909 O  O     . HOH K 5 .   ? 51.485  69.016  48.156  1.00 36.71  ? 1020 HOH A O     1 
HETATM 10910 O  O     . HOH K 5 .   ? 46.436  63.620  51.792  1.00 24.64  ? 1021 HOH A O     1 
HETATM 10911 O  O     . HOH K 5 .   ? 21.952  54.661  43.824  1.00 38.47  ? 1022 HOH A O     1 
HETATM 10912 O  O     . HOH K 5 .   ? 39.347  67.161  63.663  1.00 35.53  ? 1023 HOH A O     1 
HETATM 10913 O  O     . HOH K 5 .   ? 46.603  55.647  53.884  1.00 31.95  ? 1027 HOH A O     1 
HETATM 10914 O  O     . HOH K 5 .   ? 26.142  87.739  42.101  1.00 35.42  ? 1028 HOH A O     1 
HETATM 10915 O  O     . HOH K 5 .   ? 47.872  61.321  54.999  1.00 42.09  ? 1029 HOH A O     1 
HETATM 10916 O  O     . HOH K 5 .   ? 35.120  60.479  37.345  1.00 35.42  ? 1034 HOH A O     1 
HETATM 10917 O  O     . HOH K 5 .   ? 32.990  36.417  68.140  1.00 38.64  ? 1035 HOH A O     1 
HETATM 10918 O  O     . HOH K 5 .   ? 36.592  35.870  41.931  1.00 35.51  ? 1038 HOH A O     1 
HETATM 10919 O  O     . HOH K 5 .   ? 30.039  64.424  62.180  1.00 41.77  ? 1042 HOH A O     1 
HETATM 10920 O  O     . HOH K 5 .   ? 57.441  84.473  44.056  1.00 29.21  ? 1045 HOH A O     1 
HETATM 10921 O  O     . HOH K 5 .   ? 46.480  78.520  63.461  1.00 36.95  ? 1046 HOH A O     1 
HETATM 10922 O  O     . HOH K 5 .   ? 31.064  56.330  41.365  1.00 25.78  ? 1047 HOH A O     1 
HETATM 10923 O  O     . HOH K 5 .   ? 29.905  93.537  56.636  1.00 31.08  ? 1048 HOH A O     1 
HETATM 10924 O  O     . HOH K 5 .   ? 28.184  62.050  62.294  1.00 38.23  ? 1051 HOH A O     1 
HETATM 10925 O  O     . HOH K 5 .   ? 38.859  34.124  43.930  1.00 40.32  ? 1052 HOH A O     1 
HETATM 10926 O  O     . HOH K 5 .   ? 31.235  45.883  52.795  1.00 24.23  ? 1053 HOH A O     1 
HETATM 10927 O  O     . HOH K 5 .   ? 34.568  38.334  42.820  1.00 37.71  ? 1054 HOH A O     1 
HETATM 10928 O  O     . HOH K 5 .   ? 27.952  49.824  53.326  1.00 27.92  ? 1056 HOH A O     1 
HETATM 10929 O  O     . HOH K 5 .   ? 31.515  108.663 53.445  1.00 43.97  ? 1060 HOH A O     1 
HETATM 10930 O  O     . HOH K 5 .   ? 42.845  59.549  44.825  1.00 48.77  ? 1062 HOH A O     1 
HETATM 10931 O  O     . HOH K 5 .   ? 35.958  37.852  60.130  1.00 33.22  ? 1063 HOH A O     1 
HETATM 10932 O  O     . HOH K 5 .   ? 42.818  50.968  43.209  1.00 37.11  ? 1066 HOH A O     1 
HETATM 10933 O  O     . HOH K 5 .   ? 30.981  96.450  42.794  1.00 27.26  ? 1070 HOH A O     1 
HETATM 10934 O  O     . HOH K 5 .   ? 37.630  73.575  63.292  1.00 42.80  ? 1072 HOH A O     1 
HETATM 10935 O  O     . HOH K 5 .   ? 40.023  65.424  38.627  1.00 41.27  ? 1076 HOH A O     1 
HETATM 10936 O  O     . HOH K 5 .   ? 28.979  30.540  71.997  1.00 33.28  ? 1079 HOH A O     1 
HETATM 10937 O  O     . HOH K 5 .   ? 26.434  52.802  58.481  1.00 38.78  ? 1081 HOH A O     1 
HETATM 10938 O  O     . HOH K 5 .   ? 25.317  62.447  62.260  1.00 38.62  ? 1084 HOH A O     1 
HETATM 10939 O  O     . HOH K 5 .   ? 46.972  58.229  56.441  1.00 47.39  ? 1086 HOH A O     1 
HETATM 10940 O  O     . HOH K 5 .   ? 34.794  79.027  51.501  1.00 33.97  ? 1088 HOH A O     1 
HETATM 10941 O  O     . HOH K 5 .   ? 45.582  101.374 63.847  1.00 28.08  ? 1089 HOH A O     1 
HETATM 10942 O  O     . HOH K 5 .   ? 27.917  89.852  41.735  1.00 35.01  ? 1091 HOH A O     1 
HETATM 10943 O  O     . HOH K 5 .   ? 46.299  69.566  40.022  1.00 47.95  ? 1101 HOH A O     1 
HETATM 10944 O  O     . HOH K 5 .   ? 50.539  67.228  46.143  1.00 40.75  ? 1102 HOH A O     1 
HETATM 10945 O  O     . HOH K 5 .   ? 97.908  78.956  115.185 1.00 44.15  ? 1104 HOH A O     1 
HETATM 10946 O  O     . HOH K 5 .   ? 43.365  72.353  62.877  1.00 43.54  ? 1105 HOH A O     1 
HETATM 10947 O  O     . HOH K 5 .   ? 53.061  80.138  42.678  1.00 31.66  ? 1107 HOH A O     1 
HETATM 10948 O  O     . HOH K 5 .   ? 38.569  67.062  35.208  1.00 31.41  ? 1109 HOH A O     1 
HETATM 10949 O  O     . HOH K 5 .   ? 21.556  66.040  64.218  1.00 44.39  ? 1111 HOH A O     1 
HETATM 10950 O  O     . HOH K 5 .   ? 31.151  75.550  65.574  1.00 29.96  ? 1118 HOH A O     1 
HETATM 10951 O  O     . HOH K 5 .   ? 40.361  69.983  60.785  1.00 56.20  ? 1120 HOH A O     1 
HETATM 10952 O  O     . HOH K 5 .   ? 24.114  62.563  55.401  1.00 51.08  ? 1122 HOH A O     1 
HETATM 10953 O  O     . HOH K 5 .   ? 34.985  110.684 61.932  1.00 32.04  ? 1124 HOH A O     1 
HETATM 10954 O  O     . HOH K 5 .   ? 36.630  88.954  35.779  1.00 40.83  ? 1134 HOH A O     1 
HETATM 10955 O  O     . HOH K 5 .   ? 22.909  76.105  36.546  1.00 34.18  ? 1135 HOH A O     1 
HETATM 10956 O  O     . HOH K 5 .   ? 52.248  71.016  58.993  1.00 37.15  ? 1136 HOH A O     1 
HETATM 10957 O  O     . HOH K 5 .   ? 41.819  55.645  53.159  1.00 29.80  ? 1138 HOH A O     1 
HETATM 10958 O  O     . HOH K 5 .   ? 47.876  63.350  47.011  1.00 30.34  ? 1139 HOH A O     1 
HETATM 10959 O  O     . HOH K 5 .   ? 36.296  79.432  46.733  1.00 33.68  ? 1140 HOH A O     1 
HETATM 10960 O  O     . HOH K 5 .   ? 32.169  97.641  40.660  1.00 34.18  ? 1142 HOH A O     1 
HETATM 10961 O  O     . HOH K 5 .   ? 31.888  74.188  55.563  1.00 50.81  ? 1143 HOH A O     1 
HETATM 10962 O  O     . HOH K 5 .   ? 32.847  63.717  61.699  1.00 37.39  ? 1145 HOH A O     1 
HETATM 10963 O  O     . HOH K 5 .   ? 37.531  53.371  40.274  1.00 49.72  ? 1148 HOH A O     1 
HETATM 10964 O  O     . HOH K 5 .   ? 39.732  64.925  63.308  1.00 30.41  ? 1151 HOH A O     1 
HETATM 10965 O  O     . HOH K 5 .   ? 30.911  95.143  39.111  1.00 43.33  ? 1152 HOH A O     1 
HETATM 10966 O  O     . HOH K 5 .   ? 56.954  86.996  43.784  1.00 45.23  ? 1155 HOH A O     1 
HETATM 10967 O  O     . HOH K 5 .   ? 33.971  74.916  57.271  1.00 44.09  ? 1156 HOH A O     1 
HETATM 10968 O  O     . HOH K 5 .   ? 31.633  92.474  58.408  1.00 41.36  ? 1158 HOH A O     1 
HETATM 10969 O  O     . HOH K 5 .   ? 32.461  107.946 60.017  1.00 43.55  ? 1160 HOH A O     1 
HETATM 10970 O  O     . HOH K 5 .   ? 13.642  65.710  38.648  1.00 48.57  ? 1162 HOH A O     1 
HETATM 10971 O  O     . HOH K 5 .   ? 47.165  38.002  39.273  1.00 44.13  ? 1163 HOH A O     1 
HETATM 10972 O  O     . HOH K 5 .   ? 38.523  78.814  50.102  1.00 52.90  ? 1167 HOH A O     1 
HETATM 10973 O  O     . HOH K 5 .   ? 30.234  74.500  68.142  1.00 40.26  ? 1168 HOH A O     1 
HETATM 10974 O  O     . HOH K 5 .   ? 45.610  49.320  59.711  1.00 41.39  ? 1169 HOH A O     1 
HETATM 10975 O  O     . HOH K 5 .   ? 44.825  107.256 64.240  1.00 38.69  ? 1170 HOH A O     1 
HETATM 10976 O  O     . HOH K 5 .   ? 48.977  35.819  42.511  1.00 44.79  ? 1171 HOH A O     1 
HETATM 10977 O  O     . HOH K 5 .   ? 49.805  89.132  59.357  1.00 31.67  ? 1173 HOH A O     1 
HETATM 10978 O  O     . HOH K 5 .   ? 36.974  66.272  33.488  1.00 25.28  ? 1174 HOH A O     1 
HETATM 10979 O  O     . HOH K 5 .   ? 42.987  34.437  44.286  1.00 35.23  ? 1177 HOH A O     1 
HETATM 10980 O  O     . HOH K 5 .   ? 54.289  76.404  39.909  1.00 41.28  ? 1180 HOH A O     1 
HETATM 10981 O  O     . HOH K 5 .   ? 40.567  35.657  43.146  1.00 42.70  ? 1181 HOH A O     1 
HETATM 10982 O  O     . HOH K 5 .   ? 53.331  80.229  38.010  1.00 45.72  ? 1182 HOH A O     1 
HETATM 10983 O  O     . HOH K 5 .   ? 52.887  78.698  40.458  1.00 40.44  ? 1187 HOH A O     1 
HETATM 10984 O  O     . HOH K 5 .   ? 42.726  64.230  63.291  1.00 36.24  ? 1188 HOH A O     1 
HETATM 10985 O  O     . HOH K 5 .   ? 33.359  107.748 46.947  1.00 33.96  ? 1189 HOH A O     1 
HETATM 10986 O  O     . HOH K 5 .   ? 32.009  86.535  32.181  1.00 61.20  ? 1193 HOH A O     1 
HETATM 10987 O  O     . HOH K 5 .   ? 29.563  54.502  40.580  1.00 35.44  ? 1195 HOH A O     1 
HETATM 10988 O  O     . HOH K 5 .   ? 43.178  54.820  50.823  1.00 33.40  ? 1197 HOH A O     1 
HETATM 10989 O  O     . HOH K 5 .   ? 53.136  100.373 59.959  1.00 44.13  ? 1200 HOH A O     1 
HETATM 10990 O  O     . HOH K 5 .   ? 25.903  76.137  32.192  1.00 49.33  ? 1201 HOH A O     1 
HETATM 10991 O  O     . HOH K 5 .   ? 46.163  82.729  56.606  1.00 34.09  ? 1202 HOH A O     1 
HETATM 10992 O  O     . HOH K 5 .   ? 48.443  77.764  65.197  1.00 56.32  ? 1203 HOH A O     1 
HETATM 10993 O  O     . HOH K 5 .   ? 51.326  77.735  64.715  1.00 49.62  ? 1204 HOH A O     1 
HETATM 10994 O  O     . HOH K 5 .   ? 53.179  77.255  66.927  1.00 72.67  ? 1205 HOH A O     1 
HETATM 10995 O  O     . HOH K 5 .   ? 50.879  76.299  67.752  1.00 64.77  ? 1206 HOH A O     1 
HETATM 10996 O  O     . HOH K 5 .   ? 54.850  78.206  69.693  1.00 56.55  ? 1207 HOH A O     1 
HETATM 10997 O  O     . HOH K 5 .   ? 54.278  80.282  62.807  1.00 55.26  ? 1208 HOH A O     1 
HETATM 10998 O  O     . HOH K 5 .   ? 57.354  73.718  62.194  1.00 48.31  ? 1209 HOH A O     1 
HETATM 10999 O  O     . HOH K 5 .   ? 56.941  75.826  64.038  1.00 54.78  ? 1210 HOH A O     1 
HETATM 11000 O  O     . HOH K 5 .   ? 44.216  63.750  53.114  1.00 51.71  ? 1211 HOH A O     1 
HETATM 11001 O  O     . HOH K 5 .   ? 51.895  71.215  46.412  1.00 53.56  ? 1212 HOH A O     1 
HETATM 11002 O  O     . HOH K 5 .   ? 52.720  85.953  32.611  1.00 50.37  ? 1213 HOH A O     1 
HETATM 11003 O  O     . HOH K 5 .   ? 51.571  87.335  36.860  1.00 40.28  ? 1214 HOH A O     1 
HETATM 11004 O  O     . HOH K 5 .   ? 35.732  108.923 46.692  1.00 49.10  ? 1215 HOH A O     1 
HETATM 11005 O  O     . HOH K 5 .   ? 35.852  110.493 42.937  1.00 47.40  ? 1216 HOH A O     1 
HETATM 11006 O  O     . HOH K 5 .   ? 37.718  113.337 44.388  1.00 61.37  ? 1217 HOH A O     1 
HETATM 11007 O  O     . HOH K 5 .   ? 37.500  112.226 47.340  1.00 56.40  ? 1218 HOH A O     1 
HETATM 11008 O  O     . HOH K 5 .   ? 40.615  104.255 78.015  1.00 52.41  ? 1219 HOH A O     1 
HETATM 11009 O  O     . HOH K 5 .   ? 37.806  104.164 77.290  1.00 36.24  ? 1220 HOH A O     1 
HETATM 11010 O  O     . HOH K 5 .   ? 27.303  111.108 57.503  1.00 56.36  ? 1223 HOH A O     1 
HETATM 11011 O  O     . HOH K 5 .   ? 17.481  83.553  42.758  1.00 65.98  ? 1224 HOH A O     1 
HETATM 11012 O  O     . HOH K 5 .   ? 19.510  85.459  41.691  1.00 87.81  ? 1225 HOH A O     1 
HETATM 11013 O  O     . HOH K 5 .   ? 19.409  84.995  38.887  1.00 67.11  ? 1226 HOH A O     1 
HETATM 11014 O  O     . HOH K 5 .   ? 34.020  92.438  59.146  1.00 53.67  ? 1227 HOH A O     1 
HETATM 11015 O  O     . HOH K 5 .   ? 36.213  95.340  61.529  1.00 52.69  ? 1228 HOH A O     1 
HETATM 11016 O  O     . HOH K 5 .   ? 50.478  91.809  62.901  1.00 56.79  ? 1229 HOH A O     1 
HETATM 11017 O  O     . HOH K 5 .   ? 38.689  90.437  35.468  1.00 41.94  ? 1230 HOH A O     1 
HETATM 11018 O  O     . HOH K 5 .   ? 33.439  98.732  36.071  1.00 39.33  ? 1231 HOH A O     1 
HETATM 11019 O  O     . HOH K 5 .   ? 36.635  64.425  67.574  1.00 51.07  ? 1232 HOH A O     1 
HETATM 11020 O  O     . HOH K 5 .   ? 34.136  63.685  68.170  1.00 49.96  ? 1233 HOH A O     1 
HETATM 11021 O  O     . HOH K 5 .   ? 42.026  68.778  63.258  1.00 61.44  ? 1234 HOH A O     1 
HETATM 11022 O  O     . HOH K 5 .   ? 47.862  71.187  61.872  1.00 36.17  ? 1235 HOH A O     1 
HETATM 11023 O  O     . HOH K 5 .   ? 33.764  56.216  41.125  1.00 46.99  ? 1236 HOH A O     1 
HETATM 11024 O  O     . HOH K 5 .   ? 36.418  60.955  43.236  1.00 48.07  ? 1237 HOH A O     1 
HETATM 11025 O  O     . HOH K 5 .   ? 50.624  36.219  55.948  1.00 48.00  ? 1238 HOH A O     1 
HETATM 11026 O  O     . HOH K 5 .   ? 38.944  29.894  49.594  1.00 42.80  ? 1239 HOH A O     1 
HETATM 11027 O  O     . HOH K 5 .   ? 51.727  38.339  58.681  1.00 48.83  ? 1240 HOH A O     1 
HETATM 11028 O  O     . HOH K 5 .   ? 52.426  35.123  59.017  1.00 52.87  ? 1241 HOH A O     1 
HETATM 11029 O  O     . HOH K 5 .   ? 26.350  30.295  73.926  1.00 23.05  ? 1242 HOH A O     1 
HETATM 11030 O  O     . HOH K 5 .   ? 46.341  15.420  51.267  1.00 73.38  ? 1243 HOH A O     1 
HETATM 11031 O  O     . HOH K 5 .   ? 29.542  19.725  47.950  1.00 50.76  ? 1244 HOH A O     1 
HETATM 11032 O  O     . HOH K 5 .   ? 26.964  14.795  52.001  1.00 56.99  ? 1245 HOH A O     1 
HETATM 11033 O  O     . HOH K 5 .   ? 26.144  17.285  50.076  1.00 63.11  ? 1246 HOH A O     1 
HETATM 11034 O  O     . HOH K 5 .   ? 27.176  19.527  49.362  1.00 51.40  ? 1247 HOH A O     1 
HETATM 11035 O  O     . HOH K 5 .   ? 26.619  16.214  46.922  1.00 70.43  ? 1248 HOH A O     1 
HETATM 11036 O  O     . HOH K 5 .   ? 21.075  25.504  65.428  1.00 58.76  ? 1249 HOH A O     1 
HETATM 11037 O  O     . HOH K 5 .   ? 44.861  52.868  50.413  1.00 36.47  ? 1290 HOH A O     1 
HETATM 11038 O  O     . HOH K 5 .   ? 47.372  65.858  52.909  1.00 38.39  ? 1292 HOH A O     1 
HETATM 11039 O  O     . HOH L 5 .   ? 92.047  79.982  112.738 1.00 35.71  ? 1003 HOH B O     1 
HETATM 11040 O  O     . HOH L 5 .   ? 78.778  65.921  111.904 1.00 38.28  ? 1005 HOH B O     1 
HETATM 11041 O  O     . HOH L 5 .   ? 95.967  30.378  110.265 1.00 27.50  ? 1007 HOH B O     1 
HETATM 11042 O  O     . HOH L 5 .   ? 91.088  81.310  104.455 1.00 20.43  ? 1008 HOH B O     1 
HETATM 11043 O  O     . HOH L 5 .   ? 85.023  29.953  135.307 1.00 36.35  ? 1010 HOH B O     1 
HETATM 11044 O  O     . HOH L 5 .   ? 102.638 53.433  110.460 1.00 26.36  ? 1012 HOH B O     1 
HETATM 11045 O  O     . HOH L 5 .   ? 81.690  87.813  104.680 1.00 33.05  ? 1013 HOH B O     1 
HETATM 11046 O  O     . HOH L 5 .   ? 109.380 16.427  122.524 1.00 39.79  ? 1016 HOH B O     1 
HETATM 11047 O  O     . HOH L 5 .   ? 88.104  89.903  97.703  1.00 37.35  ? 1025 HOH B O     1 
HETATM 11048 O  O     . HOH L 5 .   ? 99.505  52.022  103.371 1.00 47.96  ? 1030 HOH B O     1 
HETATM 11049 O  O     . HOH L 5 .   ? 80.147  21.824  120.990 1.00 45.78  ? 1031 HOH B O     1 
HETATM 11050 O  O     . HOH L 5 .   ? 95.119  79.894  110.220 1.00 40.17  ? 1032 HOH B O     1 
HETATM 11051 O  O     . HOH L 5 .   ? 104.154 49.537  119.784 1.00 35.87  ? 1033 HOH B O     1 
HETATM 11052 O  O     . HOH L 5 .   ? 112.902 47.516  121.623 1.00 38.13  ? 1037 HOH B O     1 
HETATM 11053 O  O     . HOH L 5 .   ? 99.979  74.384  114.793 1.00 27.17  ? 1040 HOH B O     1 
HETATM 11054 O  O     . HOH L 5 .   ? 103.130 27.502  127.022 1.00 34.63  ? 1041 HOH B O     1 
HETATM 11055 O  O     . HOH L 5 .   ? 90.539  61.416  98.315  1.00 28.33  ? 1043 HOH B O     1 
HETATM 11056 O  O     . HOH L 5 .   ? 88.824  24.685  110.169 1.00 37.64  ? 1049 HOH B O     1 
HETATM 11057 O  O     . HOH L 5 .   ? 99.076  65.575  123.823 1.00 47.43  ? 1050 HOH B O     1 
HETATM 11058 O  O     . HOH L 5 .   ? 88.743  36.825  112.487 1.00 41.82  ? 1057 HOH B O     1 
HETATM 11059 O  O     . HOH L 5 .   ? 95.668  66.607  98.760  1.00 37.96  ? 1058 HOH B O     1 
HETATM 11060 O  O     . HOH L 5 .   ? 92.193  86.692  93.884  1.00 35.75  ? 1059 HOH B O     1 
HETATM 11061 O  O     . HOH L 5 .   ? 89.423  46.548  114.064 1.00 25.85  ? 1064 HOH B O     1 
HETATM 11062 O  O     . HOH L 5 .   ? 103.628 10.461  117.011 1.00 44.07  ? 1067 HOH B O     1 
HETATM 11063 O  O     . HOH L 5 .   ? 99.288  37.005  125.865 1.00 35.25  ? 1068 HOH B O     1 
HETATM 11064 O  O     . HOH L 5 .   ? 99.488  34.540  135.234 1.00 44.30  ? 1069 HOH B O     1 
HETATM 11065 O  O     . HOH L 5 .   ? 80.890  104.639 119.549 1.00 39.95  ? 1071 HOH B O     1 
HETATM 11066 O  O     . HOH L 5 .   ? 85.264  85.969  118.983 1.00 40.86  ? 1073 HOH B O     1 
HETATM 11067 O  O     . HOH L 5 .   ? 96.856  45.564  98.536  1.00 40.53  ? 1078 HOH B O     1 
HETATM 11068 O  O     . HOH L 5 .   ? 89.879  74.572  117.326 1.00 43.82  ? 1080 HOH B O     1 
HETATM 11069 O  O     . HOH L 5 .   ? 82.839  90.034  104.105 1.00 35.35  ? 1083 HOH B O     1 
HETATM 11070 O  O     . HOH L 5 .   ? 95.668  64.453  128.278 1.00 44.92  ? 1087 HOH B O     1 
HETATM 11071 O  O     . HOH L 5 .   ? 99.770  56.464  113.300 1.00 30.82  ? 1092 HOH B O     1 
HETATM 11072 O  O     . HOH L 5 .   ? 91.528  92.661  99.475  1.00 30.37  ? 1093 HOH B O     1 
HETATM 11073 O  O     . HOH L 5 .   ? 96.982  74.963  125.678 1.00 43.95  ? 1094 HOH B O     1 
HETATM 11074 O  O     . HOH L 5 .   ? 89.817  68.886  93.676  1.00 27.45  ? 1095 HOH B O     1 
HETATM 11075 O  O     . HOH L 5 .   ? 111.858 90.898  106.847 1.00 44.12  ? 1099 HOH B O     1 
HETATM 11076 O  O     . HOH L 5 .   ? 88.899  30.701  133.009 1.00 44.07  ? 1106 HOH B O     1 
HETATM 11077 O  O     . HOH L 5 .   ? 88.028  62.846  124.342 1.00 31.15  ? 1108 HOH B O     1 
HETATM 11078 O  O     . HOH L 5 .   ? 88.016  57.063  103.060 1.00 32.72  ? 1110 HOH B O     1 
HETATM 11079 O  O     . HOH L 5 .   ? 103.212 39.150  98.937  1.00 46.79  ? 1113 HOH B O     1 
HETATM 11080 O  O     . HOH L 5 .   ? 106.892 35.743  113.342 1.00 29.52  ? 1117 HOH B O     1 
HETATM 11081 O  O     . HOH L 5 .   ? 105.007 66.807  111.693 1.00 37.08  ? 1127 HOH B O     1 
HETATM 11082 O  O     . HOH L 5 .   ? 91.140  39.232  104.512 1.00 36.27  ? 1128 HOH B O     1 
HETATM 11083 O  O     . HOH L 5 .   ? 106.218 24.843  113.432 1.00 43.55  ? 1129 HOH B O     1 
HETATM 11084 O  O     . HOH L 5 .   ? 99.729  60.149  104.623 1.00 51.93  ? 1131 HOH B O     1 
HETATM 11085 O  O     . HOH L 5 .   ? 95.127  25.993  106.579 1.00 38.84  ? 1133 HOH B O     1 
HETATM 11086 O  O     . HOH L 5 .   ? 102.266 10.461  119.397 1.00 43.11  ? 1141 HOH B O     1 
HETATM 11087 O  O     . HOH L 5 .   ? 87.165  94.106  118.774 1.00 47.14  ? 1144 HOH B O     1 
HETATM 11088 O  O     . HOH L 5 .   ? 92.858  80.121  108.023 1.00 46.08  ? 1154 HOH B O     1 
HETATM 11089 O  O     . HOH L 5 .   ? 92.111  75.278  118.275 1.00 39.17  ? 1157 HOH B O     1 
HETATM 11090 O  O     . HOH L 5 .   ? 73.217  83.555  107.199 1.00 49.43  ? 1159 HOH B O     1 
HETATM 11091 O  O     . HOH L 5 .   ? 97.183  73.981  123.551 1.00 43.13  ? 1161 HOH B O     1 
HETATM 11092 O  O     . HOH L 5 .   ? 90.963  90.058  96.989  1.00 49.37  ? 1164 HOH B O     1 
HETATM 11093 O  O     . HOH L 5 .   ? 91.724  67.056  94.746  1.00 37.12  ? 1165 HOH B O     1 
HETATM 11094 O  O     . HOH L 5 .   ? 82.413  62.827  118.312 1.00 46.80  ? 1176 HOH B O     1 
HETATM 11095 O  O     . HOH L 5 .   ? 83.253  78.114  119.213 1.00 43.74  ? 1179 HOH B O     1 
HETATM 11096 O  O     . HOH L 5 .   ? 86.174  50.155  115.647 1.00 41.96  ? 1185 HOH B O     1 
HETATM 11097 O  O     . HOH L 5 .   ? 88.305  111.762 117.509 1.00 41.79  ? 1190 HOH B O     1 
HETATM 11098 O  O     . HOH L 5 .   ? 107.181 33.286  116.697 1.00 44.63  ? 1191 HOH B O     1 
HETATM 11099 O  O     . HOH L 5 .   ? 110.634 45.921  106.282 1.00 49.23  ? 1196 HOH B O     1 
HETATM 11100 O  O     . HOH L 5 .   ? 90.941  57.079  102.187 1.00 44.13  ? 1199 HOH B O     1 
HETATM 11101 O  O     . HOH L 5 .   ? 103.420 69.323  125.946 1.00 54.75  ? 1250 HOH B O     1 
HETATM 11102 O  O     . HOH L 5 .   ? 94.898  76.078  116.916 1.00 44.84  ? 1251 HOH B O     1 
HETATM 11103 O  O     . HOH L 5 .   ? 97.197  77.052  117.342 1.00 53.11  ? 1252 HOH B O     1 
HETATM 11104 O  O     . HOH L 5 .   ? 109.835 72.895  116.243 1.00 54.42  ? 1253 HOH B O     1 
HETATM 11105 O  O     . HOH L 5 .   ? 92.899  61.792  103.991 1.00 48.90  ? 1254 HOH B O     1 
HETATM 11106 O  O     . HOH L 5 .   ? 100.572 87.767  112.670 1.00 51.88  ? 1255 HOH B O     1 
HETATM 11107 O  O     . HOH L 5 .   ? 86.606  102.661 131.205 1.00 54.81  ? 1256 HOH B O     1 
HETATM 11108 O  O     . HOH L 5 .   ? 87.820  103.802 126.730 1.00 53.66  ? 1257 HOH B O     1 
HETATM 11109 O  O     . HOH L 5 .   ? 86.029  105.765 130.441 1.00 70.34  ? 1258 HOH B O     1 
HETATM 11110 O  O     . HOH L 5 .   ? 85.825  88.613  97.889  1.00 60.96  ? 1259 HOH B O     1 
HETATM 11111 O  O     . HOH L 5 .   ? 106.120 62.424  113.911 1.00 48.09  ? 1261 HOH B O     1 
HETATM 11112 O  O     . HOH L 5 .   ? 102.749 64.881  112.748 1.00 64.02  ? 1262 HOH B O     1 
HETATM 11113 O  O     . HOH L 5 .   ? 104.930 56.158  113.316 1.00 35.17  ? 1263 HOH B O     1 
HETATM 11114 O  O     . HOH L 5 .   ? 76.897  69.046  109.947 1.00 55.56  ? 1264 HOH B O     1 
HETATM 11115 O  O     . HOH L 5 .   ? 81.333  57.262  100.884 1.00 44.26  ? 1265 HOH B O     1 
HETATM 11116 O  O     . HOH L 5 .   ? 92.794  56.204  122.679 1.00 54.60  ? 1267 HOH B O     1 
HETATM 11117 O  O     . HOH L 5 .   ? 109.381 32.987  118.980 1.00 60.27  ? 1269 HOH B O     1 
HETATM 11118 O  O     . HOH L 5 .   ? 101.672 36.328  133.816 1.00 56.89  ? 1270 HOH B O     1 
HETATM 11119 O  O     . HOH L 5 .   ? 84.905  15.611  113.688 1.00 58.56  ? 1272 HOH B O     1 
HETATM 11120 O  O     . HOH L 5 .   ? 82.771  14.889  115.778 1.00 54.00  ? 1273 HOH B O     1 
HETATM 11121 O  O     . HOH L 5 .   ? 84.126  16.936  111.784 1.00 38.10  ? 1274 HOH B O     1 
HETATM 11122 O  O     . HOH L 5 .   ? 85.018  19.344  111.026 1.00 51.96  ? 1275 HOH B O     1 
HETATM 11123 O  O     . HOH L 5 .   ? 86.719  20.538  109.263 1.00 45.07  ? 1276 HOH B O     1 
HETATM 11124 O  O     . HOH L 5 .   ? 81.725  18.326  112.453 1.00 55.35  ? 1277 HOH B O     1 
HETATM 11125 O  O     . HOH L 5 .   ? 104.334 72.235  125.227 1.00 55.79  ? 1291 HOH B O     1 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   G   1   501 501 G   G   C . n 
A 1 2   G   2   502 502 G   G   C . n 
A 1 3   C   3   503 503 C   C   C . n 
A 1 4   C   4   504 504 C   C   C . n 
A 1 5   C   5   505 505 C   C   C . n 
A 1 6   C   6   506 506 C   C   C . n 
A 1 7   A   7   507 507 A   A   C . n 
A 1 8   U   8   508 508 U   U   C . n 
A 1 9   C   9   509 509 C   C   C . n 
A 1 10  G   10  510 510 G   G   C . n 
A 1 11  U   11  511 511 U   U   C . n 
A 1 12  C   12  512 512 C   C   C . n 
A 1 13  U   13  513 513 U   U   C . n 
A 1 14  A   14  514 514 A   A   C . n 
A 1 15  G   15  515 515 G   G   C . n 
A 1 16  C   16  516 516 C   C   C . n 
A 1 17  G   17  518 518 G   G   C . n 
A 1 18  G   18  519 519 G   G   C . n 
A 1 19  U   19  520 520 U   U   C . n 
A 1 20  U   20  520 520 U   U   C A n 
A 1 21  A   21  521 521 A   A   C . n 
A 1 22  G   22  522 522 G   G   C . n 
A 1 23  G   23  523 523 G   G   C . n 
A 1 24  A   24  524 524 A   A   C . n 
A 1 25  C   25  525 525 C   C   C . n 
A 1 26  G   26  526 526 G   G   C . n 
A 1 27  C   27  527 527 C   C   C . n 
A 1 28  G   28  528 528 G   G   C . n 
A 1 29  G   29  529 529 G   G   C . n 
A 1 30  C   30  530 530 C   C   C . n 
A 1 31  C   31  531 531 C   C   C . n 
A 1 32  C   32  532 532 C   C   C . n 
A 1 33  U   33  533 533 U   U   C . n 
A 1 34  C   34  534 534 C   C   C . n 
A 1 35  U   35  535 535 U   U   C . n 
A 1 36  C   36  536 536 C   C   C . n 
A 1 37  A   37  537 537 A   A   C . n 
A 1 38  A   38  538 538 A   A   C . n 
A 1 39  G   39  539 539 G   G   C . n 
A 1 40  G   40  540 540 G   G   C . n 
A 1 41  C   41  541 541 C   C   C . n 
A 1 42  C   42  542 542 C   C   C . n 
A 1 43  G   43  543 543 G   G   C . n 
A 1 44  A   44  544 544 A   A   C . n 
A 1 45  A   45  545 545 A   A   C . n 
A 1 46  A   46  546 546 A   A   C . n 
A 1 47  C   47  548 548 C   C   C . n 
A 1 48  G   48  549 549 G   G   C . n 
A 1 49  G   49  550 550 G   G   C . n 
A 1 50  G   50  551 551 G   G   C . n 
A 1 51  G   51  552 552 G   G   C . n 
A 1 52  G   52  553 553 G   G   C . n 
A 1 53  U   53  554 554 U   U   C . n 
A 1 54  U   54  555 555 U   U   C . n 
A 1 55  C   55  556 556 C   C   C . n 
A 1 56  G   56  557 557 G   G   C . n 
A 1 57  A   57  558 558 A   A   C . n 
A 1 58  U   58  559 559 U   U   C . n 
A 1 59  U   59  560 560 U   U   C . n 
A 1 60  C   60  561 561 C   C   C . n 
A 1 61  C   61  562 562 C   C   C . n 
A 1 62  C   62  563 563 C   C   C . n 
A 1 63  C   63  564 564 C   C   C . n 
A 1 64  C   64  565 565 C   C   C . n 
A 1 65  U   65  566 566 U   U   C . n 
A 1 66  G   66  567 567 G   G   C . n 
A 1 67  G   67  568 568 G   G   C . n 
A 1 68  G   68  569 569 G   G   C . n 
A 1 69  G   69  570 570 G   G   C . n 
A 1 70  U   70  571 571 U   U   C . n 
A 1 71  C   71  572 572 C   C   C . n 
A 1 72  A   72  573 573 A   A   C . n 
A 1 73  C   73  574 574 C   C   C . n 
A 1 74  C   74  575 575 C   C   C . n 
A 1 75  A   75  576 576 A   A   C . n 
B 1 1   G   1   501 501 G   G   D . n 
B 1 2   G   2   502 502 G   G   D . n 
B 1 3   C   3   503 503 C   C   D . n 
B 1 4   C   4   504 504 C   C   D . n 
B 1 5   C   5   505 505 C   C   D . n 
B 1 6   C   6   506 506 C   C   D . n 
B 1 7   A   7   507 507 A   A   D . n 
B 1 8   U   8   508 508 U   U   D . n 
B 1 9   C   9   509 509 C   C   D . n 
B 1 10  G   10  510 510 G   G   D . n 
B 1 11  U   11  511 511 U   U   D . n 
B 1 12  C   12  512 512 C   C   D . n 
B 1 13  U   13  513 513 U   U   D . n 
B 1 14  A   14  514 514 A   A   D . n 
B 1 15  G   15  515 515 G   G   D . n 
B 1 16  C   16  516 516 C   C   D . n 
B 1 17  G   17  518 518 G   G   D . n 
B 1 18  G   18  519 519 G   G   D . n 
B 1 19  U   19  520 520 U   U   D . n 
B 1 20  U   20  520 520 U   U   D A n 
B 1 21  A   21  521 521 A   A   D . n 
B 1 22  G   22  522 522 G   G   D . n 
B 1 23  G   23  523 523 G   G   D . n 
B 1 24  A   24  524 524 A   A   D . n 
B 1 25  C   25  525 525 C   C   D . n 
B 1 26  G   26  526 526 G   G   D . n 
B 1 27  C   27  527 527 C   C   D . n 
B 1 28  G   28  528 528 G   G   D . n 
B 1 29  G   29  529 529 G   G   D . n 
B 1 30  C   30  530 530 C   C   D . n 
B 1 31  C   31  531 531 C   C   D . n 
B 1 32  C   32  532 532 C   C   D . n 
B 1 33  U   33  533 533 U   U   D . n 
B 1 34  C   34  534 534 C   C   D . n 
B 1 35  U   35  535 535 U   U   D . n 
B 1 36  C   36  536 536 C   C   D . n 
B 1 37  A   37  537 537 A   A   D . n 
B 1 38  A   38  538 538 A   A   D . n 
B 1 39  G   39  539 539 G   G   D . n 
B 1 40  G   40  540 540 G   G   D . n 
B 1 41  C   41  541 541 C   C   D . n 
B 1 42  C   42  542 542 C   C   D . n 
B 1 43  G   43  543 543 G   G   D . n 
B 1 44  A   44  544 544 A   A   D . n 
B 1 45  A   45  545 545 A   A   D . n 
B 1 46  A   46  546 546 A   A   D . n 
B 1 47  C   47  548 548 C   C   D . n 
B 1 48  G   48  549 549 G   G   D . n 
B 1 49  G   49  550 550 G   G   D . n 
B 1 50  G   50  551 551 G   G   D . n 
B 1 51  G   51  552 552 G   G   D . n 
B 1 52  G   52  553 553 G   G   D . n 
B 1 53  U   53  554 554 U   U   D . n 
B 1 54  U   54  555 555 U   U   D . n 
B 1 55  C   55  556 556 C   C   D . n 
B 1 56  G   56  557 557 G   G   D . n 
B 1 57  A   57  558 558 A   A   D . n 
B 1 58  U   58  559 559 U   U   D . n 
B 1 59  U   59  560 560 U   U   D . n 
B 1 60  C   60  561 561 C   C   D . n 
B 1 61  C   61  562 562 C   C   D . n 
B 1 62  C   62  563 563 C   C   D . n 
B 1 63  C   63  564 564 C   C   D . n 
B 1 64  C   64  565 565 C   C   D . n 
B 1 65  U   65  566 566 U   U   D . n 
B 1 66  G   66  567 567 G   G   D . n 
B 1 67  G   67  568 568 G   G   D . n 
B 1 68  G   68  569 569 G   G   D . n 
B 1 69  G   69  570 570 G   G   D . n 
B 1 70  U   70  571 571 U   U   D . n 
B 1 71  C   71  572 572 C   C   D . n 
B 1 72  A   72  573 573 A   A   D . n 
B 1 73  C   73  574 574 C   C   D . n 
B 1 74  C   74  575 575 C   C   D . n 
B 1 75  A   75  576 576 A   A   D . n 
C 2 1   MET 1   1   1   MET MET A . n 
C 2 2   VAL 2   2   2   VAL VAL A . n 
C 2 3   VAL 3   3   3   VAL VAL A . n 
C 2 4   THR 4   4   4   THR THR A . n 
C 2 5   ARG 5   5   5   ARG ARG A . n 
C 2 6   ILE 6   6   6   ILE ILE A . n 
C 2 7   ALA 7   7   7   ALA ALA A . n 
C 2 8   PRO 8   8   8   PRO PRO A . n 
C 2 9   SER 9   9   9   SER SER A . n 
C 2 10  PRO 10  10  10  PRO PRO A . n 
C 2 11  THR 11  11  11  THR THR A . n 
C 2 12  GLY 12  12  12  GLY GLY A . n 
C 2 13  ASP 13  13  13  ASP ASP A . n 
C 2 14  PRO 14  14  14  PRO PRO A . n 
C 2 15  HIS 15  15  15  HIS HIS A . n 
C 2 16  VAL 16  16  16  VAL VAL A . n 
C 2 17  GLY 17  17  17  GLY GLY A . n 
C 2 18  THR 18  18  18  THR THR A . n 
C 2 19  ALA 19  19  19  ALA ALA A . n 
C 2 20  TYR 20  20  20  TYR TYR A . n 
C 2 21  ILE 21  21  21  ILE ILE A . n 
C 2 22  ALA 22  22  22  ALA ALA A . n 
C 2 23  LEU 23  23  23  LEU LEU A . n 
C 2 24  PHE 24  24  24  PHE PHE A . n 
C 2 25  ASN 25  25  25  ASN ASN A . n 
C 2 26  TYR 26  26  26  TYR TYR A . n 
C 2 27  ALA 27  27  27  ALA ALA A . n 
C 2 28  TRP 28  28  28  TRP TRP A . n 
C 2 29  ALA 29  29  29  ALA ALA A . n 
C 2 30  ARG 30  30  30  ARG ARG A . n 
C 2 31  ARG 31  31  31  ARG ARG A . n 
C 2 32  ASN 32  32  32  ASN ASN A . n 
C 2 33  GLY 33  33  33  GLY GLY A . n 
C 2 34  GLY 34  34  34  GLY GLY A . n 
C 2 35  ARG 35  35  35  ARG ARG A . n 
C 2 36  PHE 36  36  36  PHE PHE A . n 
C 2 37  ILE 37  37  37  ILE ILE A . n 
C 2 38  VAL 38  38  38  VAL VAL A . n 
C 2 39  ARG 39  39  39  ARG ARG A . n 
C 2 40  ILE 40  40  40  ILE ILE A . n 
C 2 41  GLU 41  41  41  GLU GLU A . n 
C 2 42  ASP 42  42  42  ASP ASP A . n 
C 2 43  THR 43  43  43  THR THR A . n 
C 2 44  ASP 44  44  44  ASP ASP A . n 
C 2 45  ARG 45  45  45  ARG ARG A . n 
C 2 46  ALA 46  46  46  ALA ALA A . n 
C 2 47  ARG 47  47  47  ARG ARG A . n 
C 2 48  TYR 48  48  48  TYR TYR A . n 
C 2 49  VAL 49  49  49  VAL VAL A . n 
C 2 50  PRO 50  50  50  PRO PRO A . n 
C 2 51  GLY 51  51  51  GLY GLY A . n 
C 2 52  ALA 52  52  52  ALA ALA A . n 
C 2 53  GLU 53  53  53  GLU GLU A . n 
C 2 54  GLU 54  54  54  GLU GLU A . n 
C 2 55  ARG 55  55  55  ARG ARG A . n 
C 2 56  ILE 56  56  56  ILE ILE A . n 
C 2 57  LEU 57  57  57  LEU LEU A . n 
C 2 58  ALA 58  58  58  ALA ALA A . n 
C 2 59  ALA 59  59  59  ALA ALA A . n 
C 2 60  LEU 60  60  60  LEU LEU A . n 
C 2 61  LYS 61  61  61  LYS LYS A . n 
C 2 62  TRP 62  62  62  TRP TRP A . n 
C 2 63  LEU 63  63  63  LEU LEU A . n 
C 2 64  GLY 64  64  64  GLY GLY A . n 
C 2 65  LEU 65  65  65  LEU LEU A . n 
C 2 66  SER 66  66  66  SER SER A . n 
C 2 67  TYR 67  67  67  TYR TYR A . n 
C 2 68  ASP 68  68  68  ASP ASP A . n 
C 2 69  GLU 69  69  69  GLU GLU A . n 
C 2 70  GLY 70  70  70  GLY GLY A . n 
C 2 71  PRO 71  71  71  PRO PRO A . n 
C 2 72  ASP 72  72  72  ASP ASP A . n 
C 2 73  VAL 73  73  73  VAL VAL A . n 
C 2 74  GLY 74  74  74  GLY GLY A . n 
C 2 75  GLY 75  75  75  GLY GLY A . n 
C 2 76  PRO 76  76  76  PRO PRO A . n 
C 2 77  HIS 77  77  77  HIS HIS A . n 
C 2 78  GLY 78  78  78  GLY GLY A . n 
C 2 79  PRO 79  79  79  PRO PRO A . n 
C 2 80  TYR 80  80  80  TYR TYR A . n 
C 2 81  ARG 81  81  81  ARG ARG A . n 
C 2 82  GLN 82  82  82  GLN GLN A . n 
C 2 83  SER 83  83  83  SER SER A . n 
C 2 84  GLU 84  84  84  GLU GLU A . n 
C 2 85  ARG 85  85  85  ARG ARG A . n 
C 2 86  LEU 86  86  86  LEU LEU A . n 
C 2 87  PRO 87  87  87  PRO PRO A . n 
C 2 88  LEU 88  88  88  LEU LEU A . n 
C 2 89  TYR 89  89  89  TYR TYR A . n 
C 2 90  GLN 90  90  90  GLN GLN A . n 
C 2 91  LYS 91  91  91  LYS LYS A . n 
C 2 92  TYR 92  92  92  TYR TYR A . n 
C 2 93  ALA 93  93  93  ALA ALA A . n 
C 2 94  GLU 94  94  94  GLU GLU A . n 
C 2 95  GLU 95  95  95  GLU GLU A . n 
C 2 96  LEU 96  96  96  LEU LEU A . n 
C 2 97  LEU 97  97  97  LEU LEU A . n 
C 2 98  LYS 98  98  98  LYS LYS A . n 
C 2 99  ARG 99  99  99  ARG ARG A . n 
C 2 100 GLY 100 100 100 GLY GLY A . n 
C 2 101 TRP 101 101 101 TRP TRP A . n 
C 2 102 ALA 102 102 102 ALA ALA A . n 
C 2 103 TYR 103 103 103 TYR TYR A . n 
C 2 104 ARG 104 104 104 ARG ARG A . n 
C 2 105 ALA 105 105 105 ALA ALA A . n 
C 2 106 PHE 106 106 106 PHE PHE A . n 
C 2 107 GLU 107 107 107 GLU GLU A . n 
C 2 108 THR 108 108 108 THR THR A . n 
C 2 109 PRO 109 109 109 PRO PRO A . n 
C 2 110 GLU 110 110 110 GLU GLU A . n 
C 2 111 GLU 111 111 111 GLU GLU A . n 
C 2 112 LEU 112 112 112 LEU LEU A . n 
C 2 113 GLU 113 113 113 GLU GLU A . n 
C 2 114 GLN 114 114 114 GLN GLN A . n 
C 2 115 ILE 115 115 115 ILE ILE A . n 
C 2 116 ARG 116 116 116 ARG ARG A . n 
C 2 117 LYS 117 117 117 LYS LYS A . n 
C 2 118 GLU 118 118 118 GLU GLU A . n 
C 2 119 LYS 119 119 119 LYS LYS A . n 
C 2 120 GLY 120 120 120 GLY GLY A . n 
C 2 121 GLY 121 121 121 GLY GLY A . n 
C 2 122 TYR 122 122 122 TYR TYR A . n 
C 2 123 ASP 123 123 123 ASP ASP A . n 
C 2 124 GLY 124 124 124 GLY GLY A . n 
C 2 125 ARG 125 125 125 ARG ARG A . n 
C 2 126 ALA 126 126 126 ALA ALA A . n 
C 2 127 ARG 127 127 127 ARG ARG A . n 
C 2 128 ASN 128 128 128 ASN ASN A . n 
C 2 129 ILE 129 129 129 ILE ILE A . n 
C 2 130 PRO 130 130 130 PRO PRO A . n 
C 2 131 PRO 131 131 131 PRO PRO A . n 
C 2 132 GLU 132 132 132 GLU GLU A . n 
C 2 133 GLU 133 133 133 GLU GLU A . n 
C 2 134 ALA 134 134 134 ALA ALA A . n 
C 2 135 GLU 135 135 135 GLU GLU A . n 
C 2 136 GLU 136 136 136 GLU GLU A . n 
C 2 137 ARG 137 137 137 ARG ARG A . n 
C 2 138 ALA 138 138 138 ALA ALA A . n 
C 2 139 ARG 139 139 139 ARG ARG A . n 
C 2 140 ARG 140 140 140 ARG ARG A . n 
C 2 141 GLY 141 141 141 GLY GLY A . n 
C 2 142 GLU 142 142 142 GLU GLU A . n 
C 2 143 PRO 143 143 143 PRO PRO A . n 
C 2 144 HIS 144 144 144 HIS HIS A . n 
C 2 145 VAL 145 145 145 VAL VAL A . n 
C 2 146 ILE 146 146 146 ILE ILE A . n 
C 2 147 ARG 147 147 147 ARG ARG A . n 
C 2 148 LEU 148 148 148 LEU LEU A . n 
C 2 149 LYS 149 149 149 LYS LYS A . n 
C 2 150 VAL 150 150 150 VAL VAL A . n 
C 2 151 PRO 151 151 151 PRO PRO A . n 
C 2 152 ARG 152 152 152 ARG ARG A . n 
C 2 153 PRO 153 153 153 PRO PRO A . n 
C 2 154 GLY 154 154 154 GLY GLY A . n 
C 2 155 THR 155 155 155 THR THR A . n 
C 2 156 THR 156 156 156 THR THR A . n 
C 2 157 GLU 157 157 157 GLU GLU A . n 
C 2 158 VAL 158 158 158 VAL VAL A . n 
C 2 159 LYS 159 159 159 LYS LYS A . n 
C 2 160 ASP 160 160 160 ASP ASP A . n 
C 2 161 GLU 161 161 161 GLU GLU A . n 
C 2 162 LEU 162 162 162 LEU LEU A . n 
C 2 163 ARG 163 163 163 ARG ARG A . n 
C 2 164 GLY 164 164 164 GLY GLY A . n 
C 2 165 VAL 165 165 165 VAL VAL A . n 
C 2 166 VAL 166 166 166 VAL VAL A . n 
C 2 167 VAL 167 167 167 VAL VAL A . n 
C 2 168 TYR 168 168 168 TYR TYR A . n 
C 2 169 ASP 169 169 169 ASP ASP A . n 
C 2 170 ASN 170 170 170 ASN ASN A . n 
C 2 171 GLN 171 171 171 GLN GLN A . n 
C 2 172 GLU 172 172 172 GLU GLU A . n 
C 2 173 ILE 173 173 173 ILE ILE A . n 
C 2 174 PRO 174 174 174 PRO PRO A . n 
C 2 175 ASP 175 175 175 ASP ASP A . n 
C 2 176 VAL 176 176 176 VAL VAL A . n 
C 2 177 VAL 177 177 177 VAL VAL A . n 
C 2 178 LEU 178 178 178 LEU LEU A . n 
C 2 179 LEU 179 179 179 LEU LEU A . n 
C 2 180 LYS 180 180 180 LYS LYS A . n 
C 2 181 SER 181 181 181 SER SER A . n 
C 2 182 ASP 182 182 182 ASP ASP A . n 
C 2 183 GLY 183 183 183 GLY GLY A . n 
C 2 184 TYR 184 184 184 TYR TYR A . n 
C 2 185 PRO 185 185 185 PRO PRO A . n 
C 2 186 THR 186 186 186 THR THR A . n 
C 2 187 TYR 187 187 187 TYR TYR A . n 
C 2 188 HIS 188 188 188 HIS HIS A . n 
C 2 189 LEU 189 189 189 LEU LEU A . n 
C 2 190 ALA 190 190 190 ALA ALA A . n 
C 2 191 ASN 191 191 191 ASN ASN A . n 
C 2 192 VAL 192 192 192 VAL VAL A . n 
C 2 193 VAL 193 193 193 VAL VAL A . n 
C 2 194 ASP 194 194 194 ASP ASP A . n 
C 2 195 ASP 195 195 195 ASP ASP A . n 
C 2 196 HIS 196 196 196 HIS HIS A . n 
C 2 197 LEU 197 197 197 LEU LEU A . n 
C 2 198 MET 198 198 198 MET MET A . n 
C 2 199 GLY 199 199 199 GLY GLY A . n 
C 2 200 VAL 200 200 200 VAL VAL A . n 
C 2 201 THR 201 201 201 THR THR A . n 
C 2 202 ASP 202 202 202 ASP ASP A . n 
C 2 203 VAL 203 203 203 VAL VAL A . n 
C 2 204 ILE 204 204 204 ILE ILE A . n 
C 2 205 ARG 205 205 205 ARG ARG A . n 
C 2 206 ALA 206 206 206 ALA ALA A . n 
C 2 207 GLU 207 207 207 GLU GLU A . n 
C 2 208 GLU 208 208 208 GLU GLU A . n 
C 2 209 TRP 209 209 209 TRP TRP A . n 
C 2 210 LEU 210 210 210 LEU LEU A . n 
C 2 211 VAL 211 211 211 VAL VAL A . n 
C 2 212 SER 212 212 212 SER SER A . n 
C 2 213 THR 213 213 213 THR THR A . n 
C 2 214 PRO 214 214 214 PRO PRO A . n 
C 2 215 ILE 215 215 215 ILE ILE A . n 
C 2 216 HIS 216 216 216 HIS HIS A . n 
C 2 217 VAL 217 217 217 VAL VAL A . n 
C 2 218 LEU 218 218 218 LEU LEU A . n 
C 2 219 LEU 219 219 219 LEU LEU A . n 
C 2 220 TYR 220 220 220 TYR TYR A . n 
C 2 221 ARG 221 221 221 ARG ARG A . n 
C 2 222 ALA 222 222 222 ALA ALA A . n 
C 2 223 PHE 223 223 223 PHE PHE A . n 
C 2 224 GLY 224 224 224 GLY GLY A . n 
C 2 225 TRP 225 225 225 TRP TRP A . n 
C 2 226 GLU 226 226 226 GLU GLU A . n 
C 2 227 ALA 227 227 227 ALA ALA A . n 
C 2 228 PRO 228 228 228 PRO PRO A . n 
C 2 229 ARG 229 229 229 ARG ARG A . n 
C 2 230 PHE 230 230 230 PHE PHE A . n 
C 2 231 TYR 231 231 231 TYR TYR A . n 
C 2 232 HIS 232 232 232 HIS HIS A . n 
C 2 233 MET 233 233 233 MET MET A . n 
C 2 234 PRO 234 234 234 PRO PRO A . n 
C 2 235 LEU 235 235 235 LEU LEU A . n 
C 2 236 LEU 236 236 236 LEU LEU A . n 
C 2 237 ARG 237 237 237 ARG ARG A . n 
C 2 238 ASN 238 238 238 ASN ASN A . n 
C 2 239 PRO 239 239 239 PRO PRO A . n 
C 2 240 ASP 240 240 240 ASP ASP A . n 
C 2 241 LYS 241 241 241 LYS LYS A . n 
C 2 242 THR 242 242 242 THR THR A . n 
C 2 243 LYS 243 243 243 LYS LYS A . n 
C 2 244 ILE 244 244 244 ILE ILE A . n 
C 2 245 SER 245 245 245 SER SER A . n 
C 2 246 LYS 246 246 246 LYS LYS A . n 
C 2 247 ARG 247 247 247 ARG ARG A . n 
C 2 248 LYS 248 248 248 LYS LYS A . n 
C 2 249 SER 249 249 249 SER SER A . n 
C 2 250 HIS 250 250 250 HIS HIS A . n 
C 2 251 THR 251 251 251 THR THR A . n 
C 2 252 SER 252 252 252 SER SER A . n 
C 2 253 LEU 253 253 253 LEU LEU A . n 
C 2 254 ASP 254 254 254 ASP ASP A . n 
C 2 255 TRP 255 255 255 TRP TRP A . n 
C 2 256 TYR 256 256 256 TYR TYR A . n 
C 2 257 LYS 257 257 257 LYS LYS A . n 
C 2 258 ALA 258 258 258 ALA ALA A . n 
C 2 259 GLU 259 259 259 GLU GLU A . n 
C 2 260 GLY 260 260 260 GLY GLY A . n 
C 2 261 PHE 261 261 261 PHE PHE A . n 
C 2 262 LEU 262 262 262 LEU LEU A . n 
C 2 263 PRO 263 263 263 PRO PRO A . n 
C 2 264 GLU 264 264 264 GLU GLU A . n 
C 2 265 ALA 265 265 265 ALA ALA A . n 
C 2 266 LEU 266 266 266 LEU LEU A . n 
C 2 267 ARG 267 267 267 ARG ARG A . n 
C 2 268 ASN 268 268 268 ASN ASN A . n 
C 2 269 TYR 269 269 269 TYR TYR A . n 
C 2 270 LEU 270 270 270 LEU LEU A . n 
C 2 271 CYS 271 271 271 CYS CYS A . n 
C 2 272 LEU 272 272 272 LEU LEU A . n 
C 2 273 MET 273 273 273 MET MET A . n 
C 2 274 GLY 274 274 274 GLY GLY A . n 
C 2 275 PHE 275 275 275 PHE PHE A . n 
C 2 276 SER 276 276 276 SER SER A . n 
C 2 277 MET 277 277 277 MET MET A . n 
C 2 278 PRO 278 278 278 PRO PRO A . n 
C 2 279 ASP 279 279 279 ASP ASP A . n 
C 2 280 GLY 280 280 280 GLY GLY A . n 
C 2 281 ARG 281 281 281 ARG ARG A . n 
C 2 282 GLU 282 282 282 GLU GLU A . n 
C 2 283 ILE 283 283 283 ILE ILE A . n 
C 2 284 PHE 284 284 284 PHE PHE A . n 
C 2 285 THR 285 285 285 THR THR A . n 
C 2 286 LEU 286 286 286 LEU LEU A . n 
C 2 287 GLU 287 287 287 GLU GLU A . n 
C 2 288 GLU 288 288 288 GLU GLU A . n 
C 2 289 PHE 289 289 289 PHE PHE A . n 
C 2 290 ILE 290 290 290 ILE ILE A . n 
C 2 291 GLN 291 291 291 GLN GLN A . n 
C 2 292 ALA 292 292 292 ALA ALA A . n 
C 2 293 PHE 293 293 293 PHE PHE A . n 
C 2 294 THR 294 294 294 THR THR A . n 
C 2 295 TRP 295 295 295 TRP TRP A . n 
C 2 296 GLU 296 296 296 GLU GLU A . n 
C 2 297 ARG 297 297 297 ARG ARG A . n 
C 2 298 VAL 298 298 298 VAL VAL A . n 
C 2 299 SER 299 299 299 SER SER A . n 
C 2 300 LEU 300 300 300 LEU LEU A . n 
C 2 301 GLY 301 301 301 GLY GLY A . n 
C 2 302 GLY 302 302 302 GLY GLY A . n 
C 2 303 PRO 303 303 303 PRO PRO A . n 
C 2 304 VAL 304 304 304 VAL VAL A . n 
C 2 305 PHE 305 305 305 PHE PHE A . n 
C 2 306 ASP 306 306 306 ASP ASP A . n 
C 2 307 LEU 307 307 307 LEU LEU A . n 
C 2 308 GLU 308 308 308 GLU GLU A . n 
C 2 309 LYS 309 309 309 LYS LYS A . n 
C 2 310 LEU 310 310 310 LEU LEU A . n 
C 2 311 ARG 311 311 311 ARG ARG A . n 
C 2 312 TRP 312 312 312 TRP TRP A . n 
C 2 313 MET 313 313 313 MET MET A . n 
C 2 314 ASN 314 314 314 ASN ASN A . n 
C 2 315 GLY 315 315 315 GLY GLY A . n 
C 2 316 LYS 316 316 316 LYS LYS A . n 
C 2 317 TYR 317 317 317 TYR TYR A . n 
C 2 318 ILE 318 318 318 ILE ILE A . n 
C 2 319 ARG 319 319 319 ARG ARG A . n 
C 2 320 GLU 320 320 320 GLU GLU A . n 
C 2 321 VAL 321 321 321 VAL VAL A . n 
C 2 322 LEU 322 322 322 LEU LEU A . n 
C 2 323 SER 323 323 323 SER SER A . n 
C 2 324 LEU 324 324 324 LEU LEU A . n 
C 2 325 GLU 325 325 325 GLU GLU A . n 
C 2 326 GLU 326 326 326 GLU GLU A . n 
C 2 327 VAL 327 327 327 VAL VAL A . n 
C 2 328 ALA 328 328 328 ALA ALA A . n 
C 2 329 GLU 329 329 329 GLU GLU A . n 
C 2 330 ARG 330 330 330 ARG ARG A . n 
C 2 331 VAL 331 331 331 VAL VAL A . n 
C 2 332 LYS 332 332 332 LYS LYS A . n 
C 2 333 PRO 333 333 333 PRO PRO A . n 
C 2 334 PHE 334 334 334 PHE PHE A . n 
C 2 335 LEU 335 335 335 LEU LEU A . n 
C 2 336 ARG 336 336 336 ARG ARG A . n 
C 2 337 GLU 337 337 337 GLU GLU A . n 
C 2 338 ALA 338 338 338 ALA ALA A . n 
C 2 339 GLY 339 339 339 GLY GLY A . n 
C 2 340 LEU 340 340 340 LEU LEU A . n 
C 2 341 SER 341 341 341 SER SER A . n 
C 2 342 TRP 342 342 342 TRP TRP A . n 
C 2 343 GLU 343 343 343 GLU GLU A . n 
C 2 344 SER 344 344 344 SER SER A . n 
C 2 345 GLU 345 345 345 GLU GLU A . n 
C 2 346 ALA 346 346 346 ALA ALA A . n 
C 2 347 TYR 347 347 347 TYR TYR A . n 
C 2 348 LEU 348 348 348 LEU LEU A . n 
C 2 349 ARG 349 349 349 ARG ARG A . n 
C 2 350 ARG 350 350 350 ARG ARG A . n 
C 2 351 ALA 351 351 351 ALA ALA A . n 
C 2 352 VAL 352 352 352 VAL VAL A . n 
C 2 353 GLU 353 353 353 GLU GLU A . n 
C 2 354 LEU 354 354 354 LEU LEU A . n 
C 2 355 MET 355 355 355 MET MET A . n 
C 2 356 ARG 356 356 356 ARG ARG A . n 
C 2 357 PRO 357 357 357 PRO PRO A . n 
C 2 358 ARG 358 358 358 ARG ARG A . n 
C 2 359 PHE 359 359 359 PHE PHE A . n 
C 2 360 ASP 360 360 360 ASP ASP A . n 
C 2 361 THR 361 361 361 THR THR A . n 
C 2 362 LEU 362 362 362 LEU LEU A . n 
C 2 363 LYS 363 363 363 LYS LYS A . n 
C 2 364 GLU 364 364 364 GLU GLU A . n 
C 2 365 PHE 365 365 365 PHE PHE A . n 
C 2 366 PRO 366 366 366 PRO PRO A . n 
C 2 367 GLU 367 367 367 GLU GLU A . n 
C 2 368 LYS 368 368 368 LYS LYS A . n 
C 2 369 ALA 369 369 369 ALA ALA A . n 
C 2 370 ARG 370 370 370 ARG ARG A . n 
C 2 371 TYR 371 371 371 TYR TYR A . n 
C 2 372 LEU 372 372 372 LEU LEU A . n 
C 2 373 PHE 373 373 373 PHE PHE A . n 
C 2 374 THR 374 374 374 THR THR A . n 
C 2 375 GLU 375 375 375 GLU GLU A . n 
C 2 376 ASP 376 376 376 ASP ASP A . n 
C 2 377 TYR 377 377 377 TYR TYR A . n 
C 2 378 PRO 378 378 378 PRO PRO A . n 
C 2 379 VAL 379 379 379 VAL VAL A . n 
C 2 380 SER 380 380 380 SER SER A . n 
C 2 381 GLU 381 381 381 GLU GLU A . n 
C 2 382 LYS 382 382 382 LYS LYS A . n 
C 2 383 ALA 383 383 383 ALA ALA A . n 
C 2 384 GLN 384 384 384 GLN GLN A . n 
C 2 385 ARG 385 385 385 ARG ARG A . n 
C 2 386 LYS 386 386 386 LYS LYS A . n 
C 2 387 LEU 387 387 387 LEU LEU A . n 
C 2 388 GLU 388 388 388 GLU GLU A . n 
C 2 389 GLU 389 389 389 GLU GLU A . n 
C 2 390 GLY 390 390 390 GLY GLY A . n 
C 2 391 LEU 391 391 391 LEU LEU A . n 
C 2 392 PRO 392 392 392 PRO PRO A . n 
C 2 393 LEU 393 393 393 LEU LEU A . n 
C 2 394 LEU 394 394 394 LEU LEU A . n 
C 2 395 LYS 395 395 395 LYS LYS A . n 
C 2 396 GLU 396 396 396 GLU GLU A . n 
C 2 397 LEU 397 397 397 LEU LEU A . n 
C 2 398 TYR 398 398 398 TYR TYR A . n 
C 2 399 PRO 399 399 399 PRO PRO A . n 
C 2 400 ARG 400 400 400 ARG ARG A . n 
C 2 401 LEU 401 401 401 LEU LEU A . n 
C 2 402 ARG 402 402 402 ARG ARG A . n 
C 2 403 ALA 403 403 403 ALA ALA A . n 
C 2 404 GLN 404 404 404 GLN GLN A . n 
C 2 405 GLU 405 405 405 GLU GLU A . n 
C 2 406 GLU 406 406 406 GLU GLU A . n 
C 2 407 TRP 407 407 407 TRP TRP A . n 
C 2 408 THR 408 408 408 THR THR A . n 
C 2 409 GLU 409 409 409 GLU GLU A . n 
C 2 410 ALA 410 410 410 ALA ALA A . n 
C 2 411 ALA 411 411 411 ALA ALA A . n 
C 2 412 LEU 412 412 412 LEU LEU A . n 
C 2 413 GLU 413 413 413 GLU GLU A . n 
C 2 414 ALA 414 414 414 ALA ALA A . n 
C 2 415 LEU 415 415 415 LEU LEU A . n 
C 2 416 LEU 416 416 416 LEU LEU A . n 
C 2 417 ARG 417 417 417 ARG ARG A . n 
C 2 418 GLY 418 418 418 GLY GLY A . n 
C 2 419 PHE 419 419 419 PHE PHE A . n 
C 2 420 ALA 420 420 420 ALA ALA A . n 
C 2 421 ALA 421 421 421 ALA ALA A . n 
C 2 422 GLU 422 422 422 GLU GLU A . n 
C 2 423 LYS 423 423 423 LYS LYS A . n 
C 2 424 GLY 424 424 424 GLY GLY A . n 
C 2 425 VAL 425 425 425 VAL VAL A . n 
C 2 426 LYS 426 426 426 LYS LYS A . n 
C 2 427 LEU 427 427 427 LEU LEU A . n 
C 2 428 GLY 428 428 428 GLY GLY A . n 
C 2 429 GLN 429 429 429 GLN GLN A . n 
C 2 430 VAL 430 430 430 VAL VAL A . n 
C 2 431 ALA 431 431 431 ALA ALA A . n 
C 2 432 GLN 432 432 432 GLN GLN A . n 
C 2 433 PRO 433 433 433 PRO PRO A . n 
C 2 434 LEU 434 434 434 LEU LEU A . n 
C 2 435 ARG 435 435 435 ARG ARG A . n 
C 2 436 ALA 436 436 436 ALA ALA A . n 
C 2 437 ALA 437 437 437 ALA ALA A . n 
C 2 438 LEU 438 438 438 LEU LEU A . n 
C 2 439 THR 439 439 439 THR THR A . n 
C 2 440 GLY 440 440 440 GLY GLY A . n 
C 2 441 SER 441 441 441 SER SER A . n 
C 2 442 LEU 442 442 442 LEU LEU A . n 
C 2 443 GLU 443 443 443 GLU GLU A . n 
C 2 444 THR 444 444 444 THR THR A . n 
C 2 445 PRO 445 445 445 PRO PRO A . n 
C 2 446 GLY 446 446 446 GLY GLY A . n 
C 2 447 LEU 447 447 447 LEU LEU A . n 
C 2 448 PHE 448 448 448 PHE PHE A . n 
C 2 449 GLU 449 449 449 GLU GLU A . n 
C 2 450 ILE 450 450 450 ILE ILE A . n 
C 2 451 LEU 451 451 451 LEU LEU A . n 
C 2 452 ALA 452 452 452 ALA ALA A . n 
C 2 453 LEU 453 453 453 LEU LEU A . n 
C 2 454 LEU 454 454 454 LEU LEU A . n 
C 2 455 GLY 455 455 455 GLY GLY A . n 
C 2 456 LYS 456 456 456 LYS LYS A . n 
C 2 457 GLU 457 457 457 GLU GLU A . n 
C 2 458 ARG 458 458 458 ARG ARG A . n 
C 2 459 ALA 459 459 459 ALA ALA A . n 
C 2 460 LEU 460 460 460 LEU LEU A . n 
C 2 461 ARG 461 461 461 ARG ARG A . n 
C 2 462 ARG 462 462 462 ARG ARG A . n 
C 2 463 LEU 463 463 463 LEU LEU A . n 
C 2 464 GLU 464 464 464 GLU GLU A . n 
C 2 465 ARG 465 465 465 ARG ARG A . n 
C 2 466 ALA 466 466 466 ALA ALA A . n 
C 2 467 LEU 467 467 467 LEU LEU A . n 
C 2 468 ALA 468 468 468 ALA ALA A . n 
D 2 1   MET 1   1   1   MET MET B . n 
D 2 2   VAL 2   2   2   VAL VAL B . n 
D 2 3   VAL 3   3   3   VAL VAL B . n 
D 2 4   THR 4   4   4   THR THR B . n 
D 2 5   ARG 5   5   5   ARG ARG B . n 
D 2 6   ILE 6   6   6   ILE ILE B . n 
D 2 7   ALA 7   7   7   ALA ALA B . n 
D 2 8   PRO 8   8   8   PRO PRO B . n 
D 2 9   SER 9   9   9   SER SER B . n 
D 2 10  PRO 10  10  10  PRO PRO B . n 
D 2 11  THR 11  11  11  THR THR B . n 
D 2 12  GLY 12  12  12  GLY GLY B . n 
D 2 13  ASP 13  13  13  ASP ASP B . n 
D 2 14  PRO 14  14  14  PRO PRO B . n 
D 2 15  HIS 15  15  15  HIS HIS B . n 
D 2 16  VAL 16  16  16  VAL VAL B . n 
D 2 17  GLY 17  17  17  GLY GLY B . n 
D 2 18  THR 18  18  18  THR THR B . n 
D 2 19  ALA 19  19  19  ALA ALA B . n 
D 2 20  TYR 20  20  20  TYR TYR B . n 
D 2 21  ILE 21  21  21  ILE ILE B . n 
D 2 22  ALA 22  22  22  ALA ALA B . n 
D 2 23  LEU 23  23  23  LEU LEU B . n 
D 2 24  PHE 24  24  24  PHE PHE B . n 
D 2 25  ASN 25  25  25  ASN ASN B . n 
D 2 26  TYR 26  26  26  TYR TYR B . n 
D 2 27  ALA 27  27  27  ALA ALA B . n 
D 2 28  TRP 28  28  28  TRP TRP B . n 
D 2 29  ALA 29  29  29  ALA ALA B . n 
D 2 30  ARG 30  30  30  ARG ARG B . n 
D 2 31  ARG 31  31  31  ARG ARG B . n 
D 2 32  ASN 32  32  32  ASN ASN B . n 
D 2 33  GLY 33  33  33  GLY GLY B . n 
D 2 34  GLY 34  34  34  GLY GLY B . n 
D 2 35  ARG 35  35  35  ARG ARG B . n 
D 2 36  PHE 36  36  36  PHE PHE B . n 
D 2 37  ILE 37  37  37  ILE ILE B . n 
D 2 38  VAL 38  38  38  VAL VAL B . n 
D 2 39  ARG 39  39  39  ARG ARG B . n 
D 2 40  ILE 40  40  40  ILE ILE B . n 
D 2 41  GLU 41  41  41  GLU GLU B . n 
D 2 42  ASP 42  42  42  ASP ASP B . n 
D 2 43  THR 43  43  43  THR THR B . n 
D 2 44  ASP 44  44  44  ASP ASP B . n 
D 2 45  ARG 45  45  45  ARG ARG B . n 
D 2 46  ALA 46  46  46  ALA ALA B . n 
D 2 47  ARG 47  47  47  ARG ARG B . n 
D 2 48  TYR 48  48  48  TYR TYR B . n 
D 2 49  VAL 49  49  49  VAL VAL B . n 
D 2 50  PRO 50  50  50  PRO PRO B . n 
D 2 51  GLY 51  51  51  GLY GLY B . n 
D 2 52  ALA 52  52  52  ALA ALA B . n 
D 2 53  GLU 53  53  53  GLU GLU B . n 
D 2 54  GLU 54  54  54  GLU GLU B . n 
D 2 55  ARG 55  55  55  ARG ARG B . n 
D 2 56  ILE 56  56  56  ILE ILE B . n 
D 2 57  LEU 57  57  57  LEU LEU B . n 
D 2 58  ALA 58  58  58  ALA ALA B . n 
D 2 59  ALA 59  59  59  ALA ALA B . n 
D 2 60  LEU 60  60  60  LEU LEU B . n 
D 2 61  LYS 61  61  61  LYS LYS B . n 
D 2 62  TRP 62  62  62  TRP TRP B . n 
D 2 63  LEU 63  63  63  LEU LEU B . n 
D 2 64  GLY 64  64  64  GLY GLY B . n 
D 2 65  LEU 65  65  65  LEU LEU B . n 
D 2 66  SER 66  66  66  SER SER B . n 
D 2 67  TYR 67  67  67  TYR TYR B . n 
D 2 68  ASP 68  68  68  ASP ASP B . n 
D 2 69  GLU 69  69  69  GLU GLU B . n 
D 2 70  GLY 70  70  70  GLY GLY B . n 
D 2 71  PRO 71  71  71  PRO PRO B . n 
D 2 72  ASP 72  72  72  ASP ASP B . n 
D 2 73  VAL 73  73  73  VAL VAL B . n 
D 2 74  GLY 74  74  74  GLY GLY B . n 
D 2 75  GLY 75  75  75  GLY GLY B . n 
D 2 76  PRO 76  76  76  PRO PRO B . n 
D 2 77  HIS 77  77  77  HIS HIS B . n 
D 2 78  GLY 78  78  78  GLY GLY B . n 
D 2 79  PRO 79  79  79  PRO PRO B . n 
D 2 80  TYR 80  80  80  TYR TYR B . n 
D 2 81  ARG 81  81  81  ARG ARG B . n 
D 2 82  GLN 82  82  82  GLN GLN B . n 
D 2 83  SER 83  83  83  SER SER B . n 
D 2 84  GLU 84  84  84  GLU GLU B . n 
D 2 85  ARG 85  85  85  ARG ARG B . n 
D 2 86  LEU 86  86  86  LEU LEU B . n 
D 2 87  PRO 87  87  87  PRO PRO B . n 
D 2 88  LEU 88  88  88  LEU LEU B . n 
D 2 89  TYR 89  89  89  TYR TYR B . n 
D 2 90  GLN 90  90  90  GLN GLN B . n 
D 2 91  LYS 91  91  91  LYS LYS B . n 
D 2 92  TYR 92  92  92  TYR TYR B . n 
D 2 93  ALA 93  93  93  ALA ALA B . n 
D 2 94  GLU 94  94  94  GLU GLU B . n 
D 2 95  GLU 95  95  95  GLU GLU B . n 
D 2 96  LEU 96  96  96  LEU LEU B . n 
D 2 97  LEU 97  97  97  LEU LEU B . n 
D 2 98  LYS 98  98  98  LYS LYS B . n 
D 2 99  ARG 99  99  99  ARG ARG B . n 
D 2 100 GLY 100 100 100 GLY GLY B . n 
D 2 101 TRP 101 101 101 TRP TRP B . n 
D 2 102 ALA 102 102 102 ALA ALA B . n 
D 2 103 TYR 103 103 103 TYR TYR B . n 
D 2 104 ARG 104 104 104 ARG ARG B . n 
D 2 105 ALA 105 105 105 ALA ALA B . n 
D 2 106 PHE 106 106 106 PHE PHE B . n 
D 2 107 GLU 107 107 107 GLU GLU B . n 
D 2 108 THR 108 108 108 THR THR B . n 
D 2 109 PRO 109 109 109 PRO PRO B . n 
D 2 110 GLU 110 110 110 GLU GLU B . n 
D 2 111 GLU 111 111 111 GLU GLU B . n 
D 2 112 LEU 112 112 112 LEU LEU B . n 
D 2 113 GLU 113 113 113 GLU GLU B . n 
D 2 114 GLN 114 114 114 GLN GLN B . n 
D 2 115 ILE 115 115 115 ILE ILE B . n 
D 2 116 ARG 116 116 116 ARG ARG B . n 
D 2 117 LYS 117 117 117 LYS LYS B . n 
D 2 118 GLU 118 118 118 GLU GLU B . n 
D 2 119 LYS 119 119 119 LYS LYS B . n 
D 2 120 GLY 120 120 120 GLY GLY B . n 
D 2 121 GLY 121 121 121 GLY GLY B . n 
D 2 122 TYR 122 122 122 TYR TYR B . n 
D 2 123 ASP 123 123 123 ASP ASP B . n 
D 2 124 GLY 124 124 124 GLY GLY B . n 
D 2 125 ARG 125 125 125 ARG ARG B . n 
D 2 126 ALA 126 126 126 ALA ALA B . n 
D 2 127 ARG 127 127 127 ARG ARG B . n 
D 2 128 ASN 128 128 128 ASN ASN B . n 
D 2 129 ILE 129 129 129 ILE ILE B . n 
D 2 130 PRO 130 130 130 PRO PRO B . n 
D 2 131 PRO 131 131 131 PRO PRO B . n 
D 2 132 GLU 132 132 132 GLU GLU B . n 
D 2 133 GLU 133 133 133 GLU GLU B . n 
D 2 134 ALA 134 134 134 ALA ALA B . n 
D 2 135 GLU 135 135 135 GLU GLU B . n 
D 2 136 GLU 136 136 136 GLU GLU B . n 
D 2 137 ARG 137 137 137 ARG ARG B . n 
D 2 138 ALA 138 138 138 ALA ALA B . n 
D 2 139 ARG 139 139 139 ARG ARG B . n 
D 2 140 ARG 140 140 140 ARG ARG B . n 
D 2 141 GLY 141 141 141 GLY GLY B . n 
D 2 142 GLU 142 142 142 GLU GLU B . n 
D 2 143 PRO 143 143 143 PRO PRO B . n 
D 2 144 HIS 144 144 144 HIS HIS B . n 
D 2 145 VAL 145 145 145 VAL VAL B . n 
D 2 146 ILE 146 146 146 ILE ILE B . n 
D 2 147 ARG 147 147 147 ARG ARG B . n 
D 2 148 LEU 148 148 148 LEU LEU B . n 
D 2 149 LYS 149 149 149 LYS LYS B . n 
D 2 150 VAL 150 150 150 VAL VAL B . n 
D 2 151 PRO 151 151 151 PRO PRO B . n 
D 2 152 ARG 152 152 152 ARG ARG B . n 
D 2 153 PRO 153 153 153 PRO PRO B . n 
D 2 154 GLY 154 154 154 GLY GLY B . n 
D 2 155 THR 155 155 155 THR THR B . n 
D 2 156 THR 156 156 156 THR THR B . n 
D 2 157 GLU 157 157 157 GLU GLU B . n 
D 2 158 VAL 158 158 158 VAL VAL B . n 
D 2 159 LYS 159 159 159 LYS LYS B . n 
D 2 160 ASP 160 160 160 ASP ASP B . n 
D 2 161 GLU 161 161 161 GLU GLU B . n 
D 2 162 LEU 162 162 162 LEU LEU B . n 
D 2 163 ARG 163 163 163 ARG ARG B . n 
D 2 164 GLY 164 164 164 GLY GLY B . n 
D 2 165 VAL 165 165 165 VAL VAL B . n 
D 2 166 VAL 166 166 166 VAL VAL B . n 
D 2 167 VAL 167 167 167 VAL VAL B . n 
D 2 168 TYR 168 168 168 TYR TYR B . n 
D 2 169 ASP 169 169 169 ASP ASP B . n 
D 2 170 ASN 170 170 170 ASN ASN B . n 
D 2 171 GLN 171 171 171 GLN GLN B . n 
D 2 172 GLU 172 172 172 GLU GLU B . n 
D 2 173 ILE 173 173 173 ILE ILE B . n 
D 2 174 PRO 174 174 174 PRO PRO B . n 
D 2 175 ASP 175 175 175 ASP ASP B . n 
D 2 176 VAL 176 176 176 VAL VAL B . n 
D 2 177 VAL 177 177 177 VAL VAL B . n 
D 2 178 LEU 178 178 178 LEU LEU B . n 
D 2 179 LEU 179 179 179 LEU LEU B . n 
D 2 180 LYS 180 180 180 LYS LYS B . n 
D 2 181 SER 181 181 181 SER SER B . n 
D 2 182 ASP 182 182 182 ASP ASP B . n 
D 2 183 GLY 183 183 183 GLY GLY B . n 
D 2 184 TYR 184 184 184 TYR TYR B . n 
D 2 185 PRO 185 185 185 PRO PRO B . n 
D 2 186 THR 186 186 186 THR THR B . n 
D 2 187 TYR 187 187 187 TYR TYR B . n 
D 2 188 HIS 188 188 188 HIS HIS B . n 
D 2 189 LEU 189 189 189 LEU LEU B . n 
D 2 190 ALA 190 190 190 ALA ALA B . n 
D 2 191 ASN 191 191 191 ASN ASN B . n 
D 2 192 VAL 192 192 192 VAL VAL B . n 
D 2 193 VAL 193 193 193 VAL VAL B . n 
D 2 194 ASP 194 194 194 ASP ASP B . n 
D 2 195 ASP 195 195 195 ASP ASP B . n 
D 2 196 HIS 196 196 196 HIS HIS B . n 
D 2 197 LEU 197 197 197 LEU LEU B . n 
D 2 198 MET 198 198 198 MET MET B . n 
D 2 199 GLY 199 199 199 GLY GLY B . n 
D 2 200 VAL 200 200 200 VAL VAL B . n 
D 2 201 THR 201 201 201 THR THR B . n 
D 2 202 ASP 202 202 202 ASP ASP B . n 
D 2 203 VAL 203 203 203 VAL VAL B . n 
D 2 204 ILE 204 204 204 ILE ILE B . n 
D 2 205 ARG 205 205 205 ARG ARG B . n 
D 2 206 ALA 206 206 206 ALA ALA B . n 
D 2 207 GLU 207 207 207 GLU GLU B . n 
D 2 208 GLU 208 208 208 GLU GLU B . n 
D 2 209 TRP 209 209 209 TRP TRP B . n 
D 2 210 LEU 210 210 210 LEU LEU B . n 
D 2 211 VAL 211 211 211 VAL VAL B . n 
D 2 212 SER 212 212 212 SER SER B . n 
D 2 213 THR 213 213 213 THR THR B . n 
D 2 214 PRO 214 214 214 PRO PRO B . n 
D 2 215 ILE 215 215 215 ILE ILE B . n 
D 2 216 HIS 216 216 216 HIS HIS B . n 
D 2 217 VAL 217 217 217 VAL VAL B . n 
D 2 218 LEU 218 218 218 LEU LEU B . n 
D 2 219 LEU 219 219 219 LEU LEU B . n 
D 2 220 TYR 220 220 220 TYR TYR B . n 
D 2 221 ARG 221 221 221 ARG ARG B . n 
D 2 222 ALA 222 222 222 ALA ALA B . n 
D 2 223 PHE 223 223 223 PHE PHE B . n 
D 2 224 GLY 224 224 224 GLY GLY B . n 
D 2 225 TRP 225 225 225 TRP TRP B . n 
D 2 226 GLU 226 226 226 GLU GLU B . n 
D 2 227 ALA 227 227 227 ALA ALA B . n 
D 2 228 PRO 228 228 228 PRO PRO B . n 
D 2 229 ARG 229 229 229 ARG ARG B . n 
D 2 230 PHE 230 230 230 PHE PHE B . n 
D 2 231 TYR 231 231 231 TYR TYR B . n 
D 2 232 HIS 232 232 232 HIS HIS B . n 
D 2 233 MET 233 233 233 MET MET B . n 
D 2 234 PRO 234 234 234 PRO PRO B . n 
D 2 235 LEU 235 235 235 LEU LEU B . n 
D 2 236 LEU 236 236 236 LEU LEU B . n 
D 2 237 ARG 237 237 237 ARG ARG B . n 
D 2 238 ASN 238 238 238 ASN ASN B . n 
D 2 239 PRO 239 239 239 PRO PRO B . n 
D 2 240 ASP 240 240 240 ASP ASP B . n 
D 2 241 LYS 241 241 241 LYS LYS B . n 
D 2 242 THR 242 242 242 THR THR B . n 
D 2 243 LYS 243 243 243 LYS LYS B . n 
D 2 244 ILE 244 244 244 ILE ILE B . n 
D 2 245 SER 245 245 245 SER SER B . n 
D 2 246 LYS 246 246 246 LYS LYS B . n 
D 2 247 ARG 247 247 247 ARG ARG B . n 
D 2 248 LYS 248 248 248 LYS LYS B . n 
D 2 249 SER 249 249 249 SER SER B . n 
D 2 250 HIS 250 250 250 HIS HIS B . n 
D 2 251 THR 251 251 251 THR THR B . n 
D 2 252 SER 252 252 252 SER SER B . n 
D 2 253 LEU 253 253 253 LEU LEU B . n 
D 2 254 ASP 254 254 254 ASP ASP B . n 
D 2 255 TRP 255 255 255 TRP TRP B . n 
D 2 256 TYR 256 256 256 TYR TYR B . n 
D 2 257 LYS 257 257 257 LYS LYS B . n 
D 2 258 ALA 258 258 258 ALA ALA B . n 
D 2 259 GLU 259 259 259 GLU GLU B . n 
D 2 260 GLY 260 260 260 GLY GLY B . n 
D 2 261 PHE 261 261 261 PHE PHE B . n 
D 2 262 LEU 262 262 262 LEU LEU B . n 
D 2 263 PRO 263 263 263 PRO PRO B . n 
D 2 264 GLU 264 264 264 GLU GLU B . n 
D 2 265 ALA 265 265 265 ALA ALA B . n 
D 2 266 LEU 266 266 266 LEU LEU B . n 
D 2 267 ARG 267 267 267 ARG ARG B . n 
D 2 268 ASN 268 268 268 ASN ASN B . n 
D 2 269 TYR 269 269 269 TYR TYR B . n 
D 2 270 LEU 270 270 270 LEU LEU B . n 
D 2 271 CYS 271 271 271 CYS CYS B . n 
D 2 272 LEU 272 272 272 LEU LEU B . n 
D 2 273 MET 273 273 273 MET MET B . n 
D 2 274 GLY 274 274 274 GLY GLY B . n 
D 2 275 PHE 275 275 275 PHE PHE B . n 
D 2 276 SER 276 276 276 SER SER B . n 
D 2 277 MET 277 277 277 MET MET B . n 
D 2 278 PRO 278 278 278 PRO PRO B . n 
D 2 279 ASP 279 279 279 ASP ASP B . n 
D 2 280 GLY 280 280 280 GLY GLY B . n 
D 2 281 ARG 281 281 281 ARG ARG B . n 
D 2 282 GLU 282 282 282 GLU GLU B . n 
D 2 283 ILE 283 283 283 ILE ILE B . n 
D 2 284 PHE 284 284 284 PHE PHE B . n 
D 2 285 THR 285 285 285 THR THR B . n 
D 2 286 LEU 286 286 286 LEU LEU B . n 
D 2 287 GLU 287 287 287 GLU GLU B . n 
D 2 288 GLU 288 288 288 GLU GLU B . n 
D 2 289 PHE 289 289 289 PHE PHE B . n 
D 2 290 ILE 290 290 290 ILE ILE B . n 
D 2 291 GLN 291 291 291 GLN GLN B . n 
D 2 292 ALA 292 292 292 ALA ALA B . n 
D 2 293 PHE 293 293 293 PHE PHE B . n 
D 2 294 THR 294 294 294 THR THR B . n 
D 2 295 TRP 295 295 295 TRP TRP B . n 
D 2 296 GLU 296 296 296 GLU GLU B . n 
D 2 297 ARG 297 297 297 ARG ARG B . n 
D 2 298 VAL 298 298 298 VAL VAL B . n 
D 2 299 SER 299 299 299 SER SER B . n 
D 2 300 LEU 300 300 300 LEU LEU B . n 
D 2 301 GLY 301 301 301 GLY GLY B . n 
D 2 302 GLY 302 302 302 GLY GLY B . n 
D 2 303 PRO 303 303 303 PRO PRO B . n 
D 2 304 VAL 304 304 304 VAL VAL B . n 
D 2 305 PHE 305 305 305 PHE PHE B . n 
D 2 306 ASP 306 306 306 ASP ASP B . n 
D 2 307 LEU 307 307 307 LEU LEU B . n 
D 2 308 GLU 308 308 308 GLU GLU B . n 
D 2 309 LYS 309 309 309 LYS LYS B . n 
D 2 310 LEU 310 310 310 LEU LEU B . n 
D 2 311 ARG 311 311 311 ARG ARG B . n 
D 2 312 TRP 312 312 312 TRP TRP B . n 
D 2 313 MET 313 313 313 MET MET B . n 
D 2 314 ASN 314 314 314 ASN ASN B . n 
D 2 315 GLY 315 315 315 GLY GLY B . n 
D 2 316 LYS 316 316 316 LYS LYS B . n 
D 2 317 TYR 317 317 317 TYR TYR B . n 
D 2 318 ILE 318 318 318 ILE ILE B . n 
D 2 319 ARG 319 319 319 ARG ARG B . n 
D 2 320 GLU 320 320 320 GLU GLU B . n 
D 2 321 VAL 321 321 321 VAL VAL B . n 
D 2 322 LEU 322 322 322 LEU LEU B . n 
D 2 323 SER 323 323 323 SER SER B . n 
D 2 324 LEU 324 324 324 LEU LEU B . n 
D 2 325 GLU 325 325 325 GLU GLU B . n 
D 2 326 GLU 326 326 326 GLU GLU B . n 
D 2 327 VAL 327 327 327 VAL VAL B . n 
D 2 328 ALA 328 328 328 ALA ALA B . n 
D 2 329 GLU 329 329 329 GLU GLU B . n 
D 2 330 ARG 330 330 330 ARG ARG B . n 
D 2 331 VAL 331 331 331 VAL VAL B . n 
D 2 332 LYS 332 332 332 LYS LYS B . n 
D 2 333 PRO 333 333 333 PRO PRO B . n 
D 2 334 PHE 334 334 334 PHE PHE B . n 
D 2 335 LEU 335 335 335 LEU LEU B . n 
D 2 336 ARG 336 336 336 ARG ARG B . n 
D 2 337 GLU 337 337 337 GLU GLU B . n 
D 2 338 ALA 338 338 338 ALA ALA B . n 
D 2 339 GLY 339 339 339 GLY GLY B . n 
D 2 340 LEU 340 340 340 LEU LEU B . n 
D 2 341 SER 341 341 341 SER SER B . n 
D 2 342 TRP 342 342 342 TRP TRP B . n 
D 2 343 GLU 343 343 343 GLU GLU B . n 
D 2 344 SER 344 344 344 SER SER B . n 
D 2 345 GLU 345 345 345 GLU GLU B . n 
D 2 346 ALA 346 346 346 ALA ALA B . n 
D 2 347 TYR 347 347 347 TYR TYR B . n 
D 2 348 LEU 348 348 348 LEU LEU B . n 
D 2 349 ARG 349 349 349 ARG ARG B . n 
D 2 350 ARG 350 350 350 ARG ARG B . n 
D 2 351 ALA 351 351 351 ALA ALA B . n 
D 2 352 VAL 352 352 352 VAL VAL B . n 
D 2 353 GLU 353 353 353 GLU GLU B . n 
D 2 354 LEU 354 354 354 LEU LEU B . n 
D 2 355 MET 355 355 355 MET MET B . n 
D 2 356 ARG 356 356 356 ARG ARG B . n 
D 2 357 PRO 357 357 357 PRO PRO B . n 
D 2 358 ARG 358 358 358 ARG ARG B . n 
D 2 359 PHE 359 359 359 PHE PHE B . n 
D 2 360 ASP 360 360 360 ASP ASP B . n 
D 2 361 THR 361 361 361 THR THR B . n 
D 2 362 LEU 362 362 362 LEU LEU B . n 
D 2 363 LYS 363 363 363 LYS LYS B . n 
D 2 364 GLU 364 364 364 GLU GLU B . n 
D 2 365 PHE 365 365 365 PHE PHE B . n 
D 2 366 PRO 366 366 366 PRO PRO B . n 
D 2 367 GLU 367 367 367 GLU GLU B . n 
D 2 368 LYS 368 368 368 LYS LYS B . n 
D 2 369 ALA 369 369 369 ALA ALA B . n 
D 2 370 ARG 370 370 370 ARG ARG B . n 
D 2 371 TYR 371 371 371 TYR TYR B . n 
D 2 372 LEU 372 372 372 LEU LEU B . n 
D 2 373 PHE 373 373 373 PHE PHE B . n 
D 2 374 THR 374 374 374 THR THR B . n 
D 2 375 GLU 375 375 375 GLU GLU B . n 
D 2 376 ASP 376 376 376 ASP ASP B . n 
D 2 377 TYR 377 377 377 TYR TYR B . n 
D 2 378 PRO 378 378 378 PRO PRO B . n 
D 2 379 VAL 379 379 379 VAL VAL B . n 
D 2 380 SER 380 380 380 SER SER B . n 
D 2 381 GLU 381 381 381 GLU GLU B . n 
D 2 382 LYS 382 382 382 LYS LYS B . n 
D 2 383 ALA 383 383 383 ALA ALA B . n 
D 2 384 GLN 384 384 384 GLN GLN B . n 
D 2 385 ARG 385 385 385 ARG ARG B . n 
D 2 386 LYS 386 386 386 LYS LYS B . n 
D 2 387 LEU 387 387 387 LEU LEU B . n 
D 2 388 GLU 388 388 388 GLU GLU B . n 
D 2 389 GLU 389 389 389 GLU GLU B . n 
D 2 390 GLY 390 390 390 GLY GLY B . n 
D 2 391 LEU 391 391 391 LEU LEU B . n 
D 2 392 PRO 392 392 392 PRO PRO B . n 
D 2 393 LEU 393 393 393 LEU LEU B . n 
D 2 394 LEU 394 394 394 LEU LEU B . n 
D 2 395 LYS 395 395 395 LYS LYS B . n 
D 2 396 GLU 396 396 396 GLU GLU B . n 
D 2 397 LEU 397 397 397 LEU LEU B . n 
D 2 398 TYR 398 398 398 TYR TYR B . n 
D 2 399 PRO 399 399 399 PRO PRO B . n 
D 2 400 ARG 400 400 400 ARG ARG B . n 
D 2 401 LEU 401 401 401 LEU LEU B . n 
D 2 402 ARG 402 402 402 ARG ARG B . n 
D 2 403 ALA 403 403 403 ALA ALA B . n 
D 2 404 GLN 404 404 404 GLN GLN B . n 
D 2 405 GLU 405 405 405 GLU GLU B . n 
D 2 406 GLU 406 406 406 GLU GLU B . n 
D 2 407 TRP 407 407 407 TRP TRP B . n 
D 2 408 THR 408 408 408 THR THR B . n 
D 2 409 GLU 409 409 409 GLU GLU B . n 
D 2 410 ALA 410 410 410 ALA ALA B . n 
D 2 411 ALA 411 411 411 ALA ALA B . n 
D 2 412 LEU 412 412 412 LEU LEU B . n 
D 2 413 GLU 413 413 413 GLU GLU B . n 
D 2 414 ALA 414 414 414 ALA ALA B . n 
D 2 415 LEU 415 415 415 LEU LEU B . n 
D 2 416 LEU 416 416 416 LEU LEU B . n 
D 2 417 ARG 417 417 417 ARG ARG B . n 
D 2 418 GLY 418 418 418 GLY GLY B . n 
D 2 419 PHE 419 419 419 PHE PHE B . n 
D 2 420 ALA 420 420 420 ALA ALA B . n 
D 2 421 ALA 421 421 421 ALA ALA B . n 
D 2 422 GLU 422 422 422 GLU GLU B . n 
D 2 423 LYS 423 423 423 LYS LYS B . n 
D 2 424 GLY 424 424 424 GLY GLY B . n 
D 2 425 VAL 425 425 425 VAL VAL B . n 
D 2 426 LYS 426 426 426 LYS LYS B . n 
D 2 427 LEU 427 427 427 LEU LEU B . n 
D 2 428 GLY 428 428 428 GLY GLY B . n 
D 2 429 GLN 429 429 429 GLN GLN B . n 
D 2 430 VAL 430 430 430 VAL VAL B . n 
D 2 431 ALA 431 431 431 ALA ALA B . n 
D 2 432 GLN 432 432 432 GLN GLN B . n 
D 2 433 PRO 433 433 433 PRO PRO B . n 
D 2 434 LEU 434 434 434 LEU LEU B . n 
D 2 435 ARG 435 435 435 ARG ARG B . n 
D 2 436 ALA 436 436 436 ALA ALA B . n 
D 2 437 ALA 437 437 437 ALA ALA B . n 
D 2 438 LEU 438 438 438 LEU LEU B . n 
D 2 439 THR 439 439 439 THR THR B . n 
D 2 440 GLY 440 440 440 GLY GLY B . n 
D 2 441 SER 441 441 441 SER SER B . n 
D 2 442 LEU 442 442 442 LEU LEU B . n 
D 2 443 GLU 443 443 443 GLU GLU B . n 
D 2 444 THR 444 444 444 THR THR B . n 
D 2 445 PRO 445 445 445 PRO PRO B . n 
D 2 446 GLY 446 446 446 GLY GLY B . n 
D 2 447 LEU 447 447 447 LEU LEU B . n 
D 2 448 PHE 448 448 448 PHE PHE B . n 
D 2 449 GLU 449 449 449 GLU GLU B . n 
D 2 450 ILE 450 450 450 ILE ILE B . n 
D 2 451 LEU 451 451 451 LEU LEU B . n 
D 2 452 ALA 452 452 452 ALA ALA B . n 
D 2 453 LEU 453 453 453 LEU LEU B . n 
D 2 454 LEU 454 454 454 LEU LEU B . n 
D 2 455 GLY 455 455 455 GLY GLY B . n 
D 2 456 LYS 456 456 456 LYS LYS B . n 
D 2 457 GLU 457 457 457 GLU GLU B . n 
D 2 458 ARG 458 458 458 ARG ARG B . n 
D 2 459 ALA 459 459 459 ALA ALA B . n 
D 2 460 LEU 460 460 460 LEU LEU B . n 
D 2 461 ARG 461 461 461 ARG ARG B . n 
D 2 462 ARG 462 462 462 ARG ARG B . n 
D 2 463 LEU 463 463 463 LEU LEU B . n 
D 2 464 GLU 464 464 464 GLU GLU B . n 
D 2 465 ARG 465 465 465 ARG ARG B . n 
D 2 466 ALA 466 466 466 ALA ALA B . n 
D 2 467 LEU 467 467 467 LEU LEU B . n 
D 2 468 ALA 468 468 468 ALA ALA B . n 
# 
_pdbx_SG_project.id                    1 
_pdbx_SG_project.project_name          'NPPSFA, National Project on Protein Structural and Functional Analyses' 
_pdbx_SG_project.full_name_of_center   'RIKEN Structural Genomics/Proteomics Initiative' 
_pdbx_SG_project.initial_of_center     RSGI 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 MG  1   901  901  MG  MG  C . 
F 3 MG  1   902  902  MG  MG  D . 
G 4 GLU 1   601  601  GLU GLU A . 
H 4 GLU 1   602  602  GLU GLU A . 
I 5 HOH 1   1006 1006 HOH HOH C . 
I 5 HOH 2   1039 1039 HOH HOH C . 
I 5 HOH 3   1055 1055 HOH HOH C . 
I 5 HOH 4   1065 1065 HOH HOH C . 
I 5 HOH 5   1075 1075 HOH HOH C . 
I 5 HOH 6   1077 1077 HOH HOH C . 
I 5 HOH 7   1082 1082 HOH HOH C . 
I 5 HOH 8   1090 1090 HOH HOH C . 
I 5 HOH 9   1098 1098 HOH HOH C . 
I 5 HOH 10  1114 1114 HOH HOH C . 
I 5 HOH 11  1116 1116 HOH HOH C . 
I 5 HOH 12  1121 1121 HOH HOH C . 
I 5 HOH 13  1123 1123 HOH HOH C . 
I 5 HOH 14  1130 1130 HOH HOH C . 
I 5 HOH 15  1132 1132 HOH HOH C . 
I 5 HOH 16  1137 1137 HOH HOH C . 
I 5 HOH 17  1147 1147 HOH HOH C . 
I 5 HOH 18  1149 1149 HOH HOH C . 
I 5 HOH 19  1150 1150 HOH HOH C . 
I 5 HOH 20  1153 1153 HOH HOH C . 
I 5 HOH 21  1178 1178 HOH HOH C . 
I 5 HOH 22  1184 1184 HOH HOH C . 
I 5 HOH 23  1186 1186 HOH HOH C . 
I 5 HOH 24  1192 1192 HOH HOH C . 
I 5 HOH 25  1279 1279 HOH HOH C . 
I 5 HOH 26  1281 1281 HOH HOH C . 
J 5 HOH 1   1024 1024 HOH HOH D . 
J 5 HOH 2   1026 1026 HOH HOH D . 
J 5 HOH 3   1036 1036 HOH HOH D . 
J 5 HOH 4   1044 1044 HOH HOH D . 
J 5 HOH 5   1061 1061 HOH HOH D . 
J 5 HOH 6   1074 1074 HOH HOH D . 
J 5 HOH 7   1085 1085 HOH HOH D . 
J 5 HOH 8   1096 1096 HOH HOH D . 
J 5 HOH 9   1097 1097 HOH HOH D . 
J 5 HOH 10  1100 1100 HOH HOH D . 
J 5 HOH 11  1103 1103 HOH HOH D . 
J 5 HOH 12  1115 1115 HOH HOH D . 
J 5 HOH 13  1125 1125 HOH HOH D . 
J 5 HOH 14  1126 1126 HOH HOH D . 
J 5 HOH 15  1146 1146 HOH HOH D . 
J 5 HOH 16  1166 1166 HOH HOH D . 
J 5 HOH 17  1172 1172 HOH HOH D . 
J 5 HOH 18  1175 1175 HOH HOH D . 
J 5 HOH 19  1183 1183 HOH HOH D . 
J 5 HOH 20  1194 1194 HOH HOH D . 
J 5 HOH 21  1198 1198 HOH HOH D . 
J 5 HOH 22  1280 1280 HOH HOH D . 
J 5 HOH 23  1282 1282 HOH HOH D . 
J 5 HOH 24  1283 1283 HOH HOH D . 
J 5 HOH 25  1284 1284 HOH HOH D . 
J 5 HOH 26  1286 1286 HOH HOH D . 
J 5 HOH 27  1287 1287 HOH HOH D . 
J 5 HOH 28  1288 1288 HOH HOH D . 
J 5 HOH 29  1289 1289 HOH HOH D . 
K 5 HOH 1   1002 1002 HOH HOH A . 
K 5 HOH 2   1004 1004 HOH HOH A . 
K 5 HOH 3   1009 1009 HOH HOH A . 
K 5 HOH 4   1011 1011 HOH HOH A . 
K 5 HOH 5   1014 1014 HOH HOH A . 
K 5 HOH 6   1015 1015 HOH HOH A . 
K 5 HOH 7   1017 1017 HOH HOH A . 
K 5 HOH 8   1018 1018 HOH HOH A . 
K 5 HOH 9   1019 1019 HOH HOH A . 
K 5 HOH 10  1020 1020 HOH HOH A . 
K 5 HOH 11  1021 1021 HOH HOH A . 
K 5 HOH 12  1022 1022 HOH HOH A . 
K 5 HOH 13  1023 1023 HOH HOH A . 
K 5 HOH 14  1027 1027 HOH HOH A . 
K 5 HOH 15  1028 1028 HOH HOH A . 
K 5 HOH 16  1029 1029 HOH HOH A . 
K 5 HOH 17  1034 1034 HOH HOH A . 
K 5 HOH 18  1035 1035 HOH HOH A . 
K 5 HOH 19  1038 1038 HOH HOH A . 
K 5 HOH 20  1042 1042 HOH HOH A . 
K 5 HOH 21  1045 1045 HOH HOH A . 
K 5 HOH 22  1046 1046 HOH HOH A . 
K 5 HOH 23  1047 1047 HOH HOH A . 
K 5 HOH 24  1048 1048 HOH HOH A . 
K 5 HOH 25  1051 1051 HOH HOH A . 
K 5 HOH 26  1052 1052 HOH HOH A . 
K 5 HOH 27  1053 1053 HOH HOH A . 
K 5 HOH 28  1054 1054 HOH HOH A . 
K 5 HOH 29  1056 1056 HOH HOH A . 
K 5 HOH 30  1060 1060 HOH HOH A . 
K 5 HOH 31  1062 1062 HOH HOH A . 
K 5 HOH 32  1063 1063 HOH HOH A . 
K 5 HOH 33  1066 1066 HOH HOH A . 
K 5 HOH 34  1070 1070 HOH HOH A . 
K 5 HOH 35  1072 1072 HOH HOH A . 
K 5 HOH 36  1076 1076 HOH HOH A . 
K 5 HOH 37  1079 1079 HOH HOH A . 
K 5 HOH 38  1081 1081 HOH HOH A . 
K 5 HOH 39  1084 1084 HOH HOH A . 
K 5 HOH 40  1086 1086 HOH HOH A . 
K 5 HOH 41  1088 1088 HOH HOH A . 
K 5 HOH 42  1089 1089 HOH HOH A . 
K 5 HOH 43  1091 1091 HOH HOH A . 
K 5 HOH 44  1101 1101 HOH HOH A . 
K 5 HOH 45  1102 1102 HOH HOH A . 
K 5 HOH 46  1104 1104 HOH HOH A . 
K 5 HOH 47  1105 1105 HOH HOH A . 
K 5 HOH 48  1107 1107 HOH HOH A . 
K 5 HOH 49  1109 1109 HOH HOH A . 
K 5 HOH 50  1111 1111 HOH HOH A . 
K 5 HOH 51  1118 1118 HOH HOH A . 
K 5 HOH 52  1120 1120 HOH HOH A . 
K 5 HOH 53  1122 1122 HOH HOH A . 
K 5 HOH 54  1124 1124 HOH HOH A . 
K 5 HOH 55  1134 1134 HOH HOH A . 
K 5 HOH 56  1135 1135 HOH HOH A . 
K 5 HOH 57  1136 1136 HOH HOH A . 
K 5 HOH 58  1138 1138 HOH HOH A . 
K 5 HOH 59  1139 1139 HOH HOH A . 
K 5 HOH 60  1140 1140 HOH HOH A . 
K 5 HOH 61  1142 1142 HOH HOH A . 
K 5 HOH 62  1143 1143 HOH HOH A . 
K 5 HOH 63  1145 1145 HOH HOH A . 
K 5 HOH 64  1148 1148 HOH HOH A . 
K 5 HOH 65  1151 1151 HOH HOH A . 
K 5 HOH 66  1152 1152 HOH HOH A . 
K 5 HOH 67  1155 1155 HOH HOH A . 
K 5 HOH 68  1156 1156 HOH HOH A . 
K 5 HOH 69  1158 1158 HOH HOH A . 
K 5 HOH 70  1160 1160 HOH HOH A . 
K 5 HOH 71  1162 1162 HOH HOH A . 
K 5 HOH 72  1163 1163 HOH HOH A . 
K 5 HOH 73  1167 1167 HOH HOH A . 
K 5 HOH 74  1168 1168 HOH HOH A . 
K 5 HOH 75  1169 1169 HOH HOH A . 
K 5 HOH 76  1170 1170 HOH HOH A . 
K 5 HOH 77  1171 1171 HOH HOH A . 
K 5 HOH 78  1173 1173 HOH HOH A . 
K 5 HOH 79  1174 1174 HOH HOH A . 
K 5 HOH 80  1177 1177 HOH HOH A . 
K 5 HOH 81  1180 1180 HOH HOH A . 
K 5 HOH 82  1181 1181 HOH HOH A . 
K 5 HOH 83  1182 1182 HOH HOH A . 
K 5 HOH 84  1187 1187 HOH HOH A . 
K 5 HOH 85  1188 1188 HOH HOH A . 
K 5 HOH 86  1189 1189 HOH HOH A . 
K 5 HOH 87  1193 1193 HOH HOH A . 
K 5 HOH 88  1195 1195 HOH HOH A . 
K 5 HOH 89  1197 1197 HOH HOH A . 
K 5 HOH 90  1200 1200 HOH HOH A . 
K 5 HOH 91  1201 1201 HOH HOH A . 
K 5 HOH 92  1202 1202 HOH HOH A . 
K 5 HOH 93  1203 1203 HOH HOH A . 
K 5 HOH 94  1204 1204 HOH HOH A . 
K 5 HOH 95  1205 1205 HOH HOH A . 
K 5 HOH 96  1206 1206 HOH HOH A . 
K 5 HOH 97  1207 1207 HOH HOH A . 
K 5 HOH 98  1208 1208 HOH HOH A . 
K 5 HOH 99  1209 1209 HOH HOH A . 
K 5 HOH 100 1210 1210 HOH HOH A . 
K 5 HOH 101 1211 1211 HOH HOH A . 
K 5 HOH 102 1212 1212 HOH HOH A . 
K 5 HOH 103 1213 1213 HOH HOH A . 
K 5 HOH 104 1214 1214 HOH HOH A . 
K 5 HOH 105 1215 1215 HOH HOH A . 
K 5 HOH 106 1216 1216 HOH HOH A . 
K 5 HOH 107 1217 1217 HOH HOH A . 
K 5 HOH 108 1218 1218 HOH HOH A . 
K 5 HOH 109 1219 1219 HOH HOH A . 
K 5 HOH 110 1220 1220 HOH HOH A . 
K 5 HOH 111 1223 1223 HOH HOH A . 
K 5 HOH 112 1224 1224 HOH HOH A . 
K 5 HOH 113 1225 1225 HOH HOH A . 
K 5 HOH 114 1226 1226 HOH HOH A . 
K 5 HOH 115 1227 1227 HOH HOH A . 
K 5 HOH 116 1228 1228 HOH HOH A . 
K 5 HOH 117 1229 1229 HOH HOH A . 
K 5 HOH 118 1230 1230 HOH HOH A . 
K 5 HOH 119 1231 1231 HOH HOH A . 
K 5 HOH 120 1232 1232 HOH HOH A . 
K 5 HOH 121 1233 1233 HOH HOH A . 
K 5 HOH 122 1234 1234 HOH HOH A . 
K 5 HOH 123 1235 1235 HOH HOH A . 
K 5 HOH 124 1236 1236 HOH HOH A . 
K 5 HOH 125 1237 1237 HOH HOH A . 
K 5 HOH 126 1238 1238 HOH HOH A . 
K 5 HOH 127 1239 1239 HOH HOH A . 
K 5 HOH 128 1240 1240 HOH HOH A . 
K 5 HOH 129 1241 1241 HOH HOH A . 
K 5 HOH 130 1242 1242 HOH HOH A . 
K 5 HOH 131 1243 1243 HOH HOH A . 
K 5 HOH 132 1244 1244 HOH HOH A . 
K 5 HOH 133 1245 1245 HOH HOH A . 
K 5 HOH 134 1246 1246 HOH HOH A . 
K 5 HOH 135 1247 1247 HOH HOH A . 
K 5 HOH 136 1248 1248 HOH HOH A . 
K 5 HOH 137 1249 1249 HOH HOH A . 
K 5 HOH 138 1290 1290 HOH HOH A . 
K 5 HOH 139 1292 1292 HOH HOH A . 
L 5 HOH 1   1003 1003 HOH HOH B . 
L 5 HOH 2   1005 1005 HOH HOH B . 
L 5 HOH 3   1007 1007 HOH HOH B . 
L 5 HOH 4   1008 1008 HOH HOH B . 
L 5 HOH 5   1010 1010 HOH HOH B . 
L 5 HOH 6   1012 1012 HOH HOH B . 
L 5 HOH 7   1013 1013 HOH HOH B . 
L 5 HOH 8   1016 1016 HOH HOH B . 
L 5 HOH 9   1025 1025 HOH HOH B . 
L 5 HOH 10  1030 1030 HOH HOH B . 
L 5 HOH 11  1031 1031 HOH HOH B . 
L 5 HOH 12  1032 1032 HOH HOH B . 
L 5 HOH 13  1033 1033 HOH HOH B . 
L 5 HOH 14  1037 1037 HOH HOH B . 
L 5 HOH 15  1040 1040 HOH HOH B . 
L 5 HOH 16  1041 1041 HOH HOH B . 
L 5 HOH 17  1043 1043 HOH HOH B . 
L 5 HOH 18  1049 1049 HOH HOH B . 
L 5 HOH 19  1050 1050 HOH HOH B . 
L 5 HOH 20  1057 1057 HOH HOH B . 
L 5 HOH 21  1058 1058 HOH HOH B . 
L 5 HOH 22  1059 1059 HOH HOH B . 
L 5 HOH 23  1064 1064 HOH HOH B . 
L 5 HOH 24  1067 1067 HOH HOH B . 
L 5 HOH 25  1068 1068 HOH HOH B . 
L 5 HOH 26  1069 1069 HOH HOH B . 
L 5 HOH 27  1071 1071 HOH HOH B . 
L 5 HOH 28  1073 1073 HOH HOH B . 
L 5 HOH 29  1078 1078 HOH HOH B . 
L 5 HOH 30  1080 1080 HOH HOH B . 
L 5 HOH 31  1083 1083 HOH HOH B . 
L 5 HOH 32  1087 1087 HOH HOH B . 
L 5 HOH 33  1092 1092 HOH HOH B . 
L 5 HOH 34  1093 1093 HOH HOH B . 
L 5 HOH 35  1094 1094 HOH HOH B . 
L 5 HOH 36  1095 1095 HOH HOH B . 
L 5 HOH 37  1099 1099 HOH HOH B . 
L 5 HOH 38  1106 1106 HOH HOH B . 
L 5 HOH 39  1108 1108 HOH HOH B . 
L 5 HOH 40  1110 1110 HOH HOH B . 
L 5 HOH 41  1113 1113 HOH HOH B . 
L 5 HOH 42  1117 1117 HOH HOH B . 
L 5 HOH 43  1127 1127 HOH HOH B . 
L 5 HOH 44  1128 1128 HOH HOH B . 
L 5 HOH 45  1129 1129 HOH HOH B . 
L 5 HOH 46  1131 1131 HOH HOH B . 
L 5 HOH 47  1133 1133 HOH HOH B . 
L 5 HOH 48  1141 1141 HOH HOH B . 
L 5 HOH 49  1144 1144 HOH HOH B . 
L 5 HOH 50  1154 1154 HOH HOH B . 
L 5 HOH 51  1157 1157 HOH HOH B . 
L 5 HOH 52  1159 1159 HOH HOH B . 
L 5 HOH 53  1161 1161 HOH HOH B . 
L 5 HOH 54  1164 1164 HOH HOH B . 
L 5 HOH 55  1165 1165 HOH HOH B . 
L 5 HOH 56  1176 1176 HOH HOH B . 
L 5 HOH 57  1179 1179 HOH HOH B . 
L 5 HOH 58  1185 1185 HOH HOH B . 
L 5 HOH 59  1190 1190 HOH HOH B . 
L 5 HOH 60  1191 1191 HOH HOH B . 
L 5 HOH 61  1196 1196 HOH HOH B . 
L 5 HOH 62  1199 1199 HOH HOH B . 
L 5 HOH 63  1250 1250 HOH HOH B . 
L 5 HOH 64  1251 1251 HOH HOH B . 
L 5 HOH 65  1252 1252 HOH HOH B . 
L 5 HOH 66  1253 1253 HOH HOH B . 
L 5 HOH 67  1254 1254 HOH HOH B . 
L 5 HOH 68  1255 1255 HOH HOH B . 
L 5 HOH 69  1256 1256 HOH HOH B . 
L 5 HOH 70  1257 1257 HOH HOH B . 
L 5 HOH 71  1258 1258 HOH HOH B . 
L 5 HOH 72  1259 1259 HOH HOH B . 
L 5 HOH 73  1261 1261 HOH HOH B . 
L 5 HOH 74  1262 1262 HOH HOH B . 
L 5 HOH 75  1263 1263 HOH HOH B . 
L 5 HOH 76  1264 1264 HOH HOH B . 
L 5 HOH 77  1265 1265 HOH HOH B . 
L 5 HOH 78  1267 1267 HOH HOH B . 
L 5 HOH 79  1269 1269 HOH HOH B . 
L 5 HOH 80  1270 1270 HOH HOH B . 
L 5 HOH 81  1272 1272 HOH HOH B . 
L 5 HOH 82  1273 1273 HOH HOH B . 
L 5 HOH 83  1274 1274 HOH HOH B . 
L 5 HOH 84  1275 1275 HOH HOH B . 
L 5 HOH 85  1276 1276 HOH HOH B . 
L 5 HOH 86  1277 1277 HOH HOH B . 
L 5 HOH 87  1291 1291 HOH HOH B . 
# 
loop_
_pdbx_struct_assembly.id 
_pdbx_struct_assembly.details 
_pdbx_struct_assembly.method_details 
_pdbx_struct_assembly.oligomeric_details 
_pdbx_struct_assembly.oligomeric_count 
1 author_defined_assembly ? dimeric 2 
2 author_defined_assembly ? dimeric 2 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,E,G,H,I,K 
2 1 B,D,F,J,L     
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2006-09-05 
2 'Structure model' 1 1 2008-04-30 
3 'Structure model' 1 2 2011-07-13 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Version format compliance' 
2 3 'Structure model' 'Version format compliance' 
# 
loop_
_software.name 
_software.classification 
_software.version 
_software.citation_id 
_software.pdbx_ordinal 
CNS       refinement       1.1 ? 1 
HKL-2000  'data reduction' .   ? 2 
SCALEPACK 'data scaling'   .   ? 3 
CNS       phasing          .   ? 4 
# 
_pdbx_validate_symm_contact.id                1 
_pdbx_validate_symm_contact.PDB_model_num     1 
_pdbx_validate_symm_contact.auth_atom_id_1    O 
_pdbx_validate_symm_contact.auth_asym_id_1    A 
_pdbx_validate_symm_contact.auth_comp_id_1    GLU 
_pdbx_validate_symm_contact.auth_seq_id_1     343 
_pdbx_validate_symm_contact.PDB_ins_code_1    ? 
_pdbx_validate_symm_contact.label_alt_id_1    ? 
_pdbx_validate_symm_contact.site_symmetry_1   1_555 
_pdbx_validate_symm_contact.auth_atom_id_2    O 
_pdbx_validate_symm_contact.auth_asym_id_2    B 
_pdbx_validate_symm_contact.auth_comp_id_2    PRO 
_pdbx_validate_symm_contact.auth_seq_id_2     50 
_pdbx_validate_symm_contact.PDB_ins_code_2    ? 
_pdbx_validate_symm_contact.label_alt_id_2    ? 
_pdbx_validate_symm_contact.site_symmetry_2   6_654 
_pdbx_validate_symm_contact.dist              2.11 
# 
loop_
_pdbx_validate_rmsd_bond.id 
_pdbx_validate_rmsd_bond.PDB_model_num 
_pdbx_validate_rmsd_bond.auth_atom_id_1 
_pdbx_validate_rmsd_bond.auth_asym_id_1 
_pdbx_validate_rmsd_bond.auth_comp_id_1 
_pdbx_validate_rmsd_bond.auth_seq_id_1 
_pdbx_validate_rmsd_bond.PDB_ins_code_1 
_pdbx_validate_rmsd_bond.label_alt_id_1 
_pdbx_validate_rmsd_bond.auth_atom_id_2 
_pdbx_validate_rmsd_bond.auth_asym_id_2 
_pdbx_validate_rmsd_bond.auth_comp_id_2 
_pdbx_validate_rmsd_bond.auth_seq_id_2 
_pdbx_validate_rmsd_bond.PDB_ins_code_2 
_pdbx_validate_rmsd_bond.label_alt_id_2 
_pdbx_validate_rmsd_bond.bond_value 
_pdbx_validate_rmsd_bond.bond_target_value 
_pdbx_validate_rmsd_bond.bond_deviation 
_pdbx_validate_rmsd_bond.bond_standard_deviation 
_pdbx_validate_rmsd_bond.linker_flag 
1 1 P C G 501 ? ? OP3 C G 501 ? ? 1.520 1.607 -0.087 0.012 N 
2 1 P D G 501 ? ? OP3 D G 501 ? ? 1.525 1.607 -0.082 0.012 N 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1  1 "C2'" C G   518 ? ? "C3'" C G   518 ? ? "O3'" C G   518 ? ? 124.92 113.70 11.22  1.60 N 
2  1 "C2'" C G   519 ? ? "C3'" C G   519 ? ? "O3'" C G   519 ? ? 124.90 113.70 11.20  1.60 N 
3  1 "C2'" C A   558 ? ? "C3'" C A   558 ? ? "O3'" C A   558 ? ? 125.76 113.70 12.06  1.60 N 
4  1 "C2'" C A   573 ? ? "C3'" C A   573 ? ? "O3'" C A   573 ? ? 125.16 113.70 11.46  1.60 N 
5  1 "C2'" C C   574 ? ? "C3'" C C   574 ? ? "O3'" C C   574 ? ? 124.75 113.70 11.05  1.60 N 
6  1 "C2'" C A   576 ? ? "C3'" C A   576 ? ? "O3'" C A   576 ? ? 125.69 113.70 11.99  1.60 N 
7  1 "C2'" D A   507 ? ? "C3'" D A   507 ? ? "O3'" D A   507 ? ? 125.44 113.70 11.74  1.60 N 
8  1 "C2'" D G   518 ? ? "C3'" D G   518 ? ? "O3'" D G   518 ? ? 124.73 113.70 11.03  1.60 N 
9  1 "C2'" D G   519 ? ? "C3'" D G   519 ? ? "O3'" D G   519 ? ? 124.01 113.70 10.31  1.60 N 
10 1 "C2'" D A   558 ? ? "C3'" D A   558 ? ? "O3'" D A   558 ? ? 125.93 113.70 12.23  1.60 N 
11 1 "C2'" D A   573 ? ? "C3'" D A   573 ? ? "O3'" D A   573 ? ? 125.46 113.70 11.76  1.60 N 
12 1 "C2'" D C   574 ? ? "C3'" D C   574 ? ? "O3'" D C   574 ? ? 125.37 113.70 11.67  1.60 N 
13 1 C     B LYS 332 ? ? N     B PRO 333 ? ? CA    B PRO 333 ? ? 108.86 119.30 -10.44 1.50 Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 GLU A 41  ? ? -101.17 71.63   
2 1 LYS A 241 ? ? 80.87   -2.15   
3 1 ASP B 42  ? ? -103.59 45.43   
4 1 LYS B 241 ? ? 78.65   -5.51   
5 1 PRO B 445 ? ? -77.02  -169.79 
# 
loop_
_pdbx_validate_planes.id 
_pdbx_validate_planes.PDB_model_num 
_pdbx_validate_planes.auth_comp_id 
_pdbx_validate_planes.auth_asym_id 
_pdbx_validate_planes.auth_seq_id 
_pdbx_validate_planes.PDB_ins_code 
_pdbx_validate_planes.label_alt_id 
_pdbx_validate_planes.rmsd 
_pdbx_validate_planes.type 
1 1 G C 515 ? ? 0.071 'SIDE CHAIN' 
2 1 U C 535 ? ? 0.065 'SIDE CHAIN' 
3 1 A C 545 ? ? 0.058 'SIDE CHAIN' 
4 1 C C 574 ? ? 0.077 'SIDE CHAIN' 
5 1 A C 576 ? ? 0.058 'SIDE CHAIN' 
6 1 G D 515 ? ? 0.058 'SIDE CHAIN' 
7 1 A D 545 ? ? 0.067 'SIDE CHAIN' 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
2CV0 'double helix'         
2CV0 'a-form double helix'  
2CV0 'parallel strands'     
2CV0 'hairpin loop'         
2CV0 'mismatched base pair' 
2CV0 'four-way junction'    
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 A G 1  1_555 A C 71 1_555 -0.151 -0.260 0.161  0.604   -14.221 -5.975  1  C_G501:C572_C C 501 ? C 572 ? 19 1 
1 A G 2  1_555 A U 70 1_555 -2.402 -0.514 0.782  17.414  -7.437  -4.887  2  C_G502:U571_C C 502 ? C 571 ? 28 ? 
1 A C 3  1_555 A G 69 1_555 -0.014 -0.079 0.258  13.485  -13.119 -3.928  3  C_C503:G570_C C 503 ? C 570 ? 19 1 
1 A C 4  1_555 A G 68 1_555 0.107  0.066  0.299  8.403   -4.646  0.002   4  C_C504:G569_C C 504 ? C 569 ? 19 1 
1 A C 5  1_555 A G 67 1_555 0.163  -0.095 -0.155 11.573  -15.498 -2.918  5  C_C505:G568_C C 505 ? C 568 ? 19 1 
1 A C 6  1_555 A G 66 1_555 0.168  -0.146 0.342  2.180   -13.105 0.786   6  C_C506:G567_C C 506 ? C 567 ? 19 1 
1 A A 7  1_555 A U 65 1_555 0.636  0.098  -0.109 -4.701  -9.002  -5.816  7  C_A507:U566_C C 507 ? C 566 ? 20 1 
1 A G 48 1_555 A C 64 1_555 -0.747 0.150  0.061  -9.576  -9.888  4.678   8  C_G549:C565_C C 549 ? C 565 ? 19 1 
1 A G 49 1_555 A C 63 1_555 -0.139 -0.114 -0.186 -5.949  -10.339 -0.392  9  C_G550:C564_C C 550 ? C 564 ? 19 1 
1 A G 50 1_555 A C 62 1_555 0.117  0.129  -0.117 -2.327  1.085   5.413   10 C_G551:C563_C C 551 ? C 563 ? 19 1 
1 A G 51 1_555 A C 61 1_555 -0.225 -0.103 -0.531 -4.074  -8.054  4.649   11 C_G552:C562_C C 552 ? C 562 ? 19 1 
1 A G 52 1_555 A C 60 1_555 0.109  0.150  0.768  3.157   7.007   2.249   12 C_G553:C561_C C 553 ? C 561 ? 19 1 
1 A U 53 1_555 A A 57 1_555 4.179  -1.617 0.861  -0.298  2.304   -97.197 13 C_U554:A558_C C 554 ? C 558 ? 24 4 
1 A U 54 1_555 A G 17 1_555 0.150  -6.062 0.819  16.835  -0.544  -95.174 14 C_U555:G518_C C 555 ? C 518 ? ?  2 
1 A A 38 1_555 A C 32 1_555 -4.810 -0.766 1.438  15.242  7.222   4.122   15 C_A538:C532_C C 538 ? C 532 ? ?  ? 
1 A G 39 1_555 A C 31 1_555 -0.358 -0.136 0.336  8.874   -12.891 2.441   16 C_G539:C531_C C 539 ? C 531 ? 19 1 
1 A G 40 1_555 A C 30 1_555 -0.633 -0.169 -0.043 3.323   -9.960  6.594   17 C_G540:C530_C C 540 ? C 530 ? 19 1 
1 A C 41 1_555 A G 29 1_555 0.193  -0.279 0.010  5.486   -8.474  0.533   18 C_C541:G529_C C 541 ? C 529 ? 19 1 
1 A C 42 1_555 A G 28 1_555 0.299  -0.338 0.037  -0.262  -10.069 1.744   19 C_C542:G528_C C 542 ? C 528 ? 19 1 
1 A G 43 1_555 A C 27 1_555 0.055  -0.059 -0.149 -18.595 -22.494 0.638   20 C_G543:C527_C C 543 ? C 527 ? 19 1 
1 A A 44 1_555 A G 26 1_555 -0.144 1.564  -0.077 -20.244 -22.604 -12.698 21 C_A544:G526_C C 544 ? C 526 ? 8  ? 
1 A G 10 1_555 A C 25 1_555 -0.543 -0.039 0.206  8.554   2.140   0.905   22 C_G510:C525_C C 510 ? C 525 ? 19 1 
1 A U 11 1_555 A A 24 1_555 -0.186 -0.130 -0.024 -1.235  -8.341  6.507   23 C_U511:A524_C C 511 ? C 524 ? 20 1 
1 A C 12 1_555 A G 23 1_555 0.025  -0.090 0.180  -6.038  -6.755  1.257   24 C_C512:G523_C C 512 ? C 523 ? 19 1 
1 A U 13 1_555 A G 22 1_555 2.306  -0.453 -0.196 5.455   -1.730  6.672   25 C_U513:G522_C C 513 ? C 522 ? 28 1 
1 A A 14 1_555 A U 8  1_555 -3.976 -2.063 0.924  9.047   16.256  -94.190 26 C_A514:U508_C C 514 ? C 508 ? 24 4 
1 A G 15 1_555 A C 47 1_555 -0.112 3.416  -0.428 0.389   4.313   164.862 27 C_G515:C548_C C 515 ? C 548 ? 22 2 
1 A G 18 1_555 A C 55 1_555 0.115  -0.025 0.665  29.071  -32.905 2.618   28 C_G519:C556_C C 519 ? C 556 ? 19 1 
1 B G 1  1_555 B C 71 1_555 -0.073 -0.233 0.335  5.353   -14.483 -5.653  29 D_G501:C572_D D 501 ? D 572 ? 19 1 
1 B G 2  1_555 B U 70 1_555 -2.375 -0.525 0.901  17.518  -7.423  -5.778  30 D_G502:U571_D D 502 ? D 571 ? 28 ? 
1 B C 3  1_555 B G 69 1_555 -0.024 -0.118 0.052  17.534  -15.447 -4.543  31 D_C503:G570_D D 503 ? D 570 ? 19 1 
1 B C 4  1_555 B G 68 1_555 0.163  0.030  -0.050 14.993  -6.389  0.710   32 D_C504:G569_D D 504 ? D 569 ? 19 1 
1 B C 5  1_555 B G 67 1_555 0.139  -0.138 -0.030 15.088  -12.540 -3.556  33 D_C505:G568_D D 505 ? D 568 ? 19 1 
1 B C 6  1_555 B G 66 1_555 0.313  -0.113 0.215  5.119   -13.987 1.335   34 D_C506:G567_D D 506 ? D 567 ? 19 1 
1 B A 7  1_555 B U 65 1_555 0.790  0.023  -0.136 -0.482  -9.706  -6.352  35 D_A507:U566_D D 507 ? D 566 ? 20 1 
1 B G 48 1_555 B C 64 1_555 -0.795 0.151  0.237  -4.370  -11.548 4.095   36 D_G549:C565_D D 549 ? D 565 ? 19 1 
1 B G 49 1_555 B C 63 1_555 -0.088 -0.119 -0.195 -3.208  -9.127  -0.240  37 D_G550:C564_D D 550 ? D 564 ? 19 1 
1 B G 50 1_555 B C 62 1_555 0.195  0.135  -0.115 -1.055  1.804   4.699   38 D_G551:C563_D D 551 ? D 563 ? 19 1 
1 B G 51 1_555 B C 61 1_555 -0.137 -0.089 -0.499 -2.875  -7.043  3.944   39 D_G552:C562_D D 552 ? D 562 ? 19 1 
1 B G 52 1_555 B C 60 1_555 0.102  0.185  0.527  1.420   7.519   2.397   40 D_G553:C561_D D 553 ? D 561 ? 19 1 
1 B U 53 1_555 B A 57 1_555 4.172  -1.642 0.933  -0.143  3.257   -96.971 41 D_U554:A558_D D 554 ? D 558 ? 24 4 
1 B U 54 1_555 B G 17 1_555 0.228  -6.546 0.863  16.729  1.767   -96.462 42 D_U555:G518_D D 555 ? D 518 ? ?  2 
1 B A 38 1_555 B C 32 1_555 -4.864 -0.826 1.352  16.575  0.016   1.631   43 D_A538:C532_D D 538 ? D 532 ? ?  ? 
1 B G 39 1_555 B C 31 1_555 -0.381 -0.170 0.300  8.521   -12.769 1.612   44 D_G539:C531_D D 539 ? D 531 ? 19 1 
1 B G 40 1_555 B C 30 1_555 -0.583 -0.172 0.183  2.710   -11.210 6.950   45 D_G540:C530_D D 540 ? D 530 ? 19 1 
1 B C 41 1_555 B G 29 1_555 0.179  -0.325 0.024  4.520   -13.194 0.386   46 D_C541:G529_D D 541 ? D 529 ? 19 1 
1 B C 42 1_555 B G 28 1_555 0.194  -0.317 -0.073 0.232   -12.313 3.273   47 D_C542:G528_D D 542 ? D 528 ? 19 1 
1 B G 43 1_555 B C 27 1_555 -0.068 -0.129 0.155  -14.654 -21.035 1.670   48 D_G543:C527_D D 543 ? D 527 ? 19 1 
1 B A 44 1_555 B G 26 1_555 -0.268 1.547  0.020  -19.318 -19.486 -13.550 49 D_A544:G526_D D 544 ? D 526 ? 8  1 
1 B G 10 1_555 B C 25 1_555 -0.562 -0.044 0.149  8.423   2.167   1.145   50 D_G510:C525_D D 510 ? D 525 ? 19 1 
1 B U 11 1_555 B A 24 1_555 -0.174 -0.118 0.155  -0.100  -8.595  7.747   51 D_U511:A524_D D 511 ? D 524 ? 20 1 
1 B C 12 1_555 B G 23 1_555 0.141  -0.127 0.093  -4.418  -3.745  1.012   52 D_C512:G523_D D 512 ? D 523 ? 19 1 
1 B U 13 1_555 B G 22 1_555 2.262  -0.485 -0.037 4.900   -3.526  6.518   53 D_U513:G522_D D 513 ? D 522 ? 28 1 
1 B A 14 1_555 B U 8  1_555 -4.030 -1.945 0.850  8.475   14.110  -96.057 54 D_A514:U508_D D 514 ? D 508 ? 24 4 
1 B G 15 1_555 B C 47 1_555 -0.165 3.792  -0.355 0.890   -0.624  162.994 55 D_G515:C548_D D 515 ? D 548 ? 22 2 
1 B G 18 1_555 B C 55 1_555 -0.075 0.507  0.662  34.258  -35.790 0.765   56 D_G519:C556_D D 519 ? D 556 ? ?  ? 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 A G 1  1_555 A C 71 1_555 A G 2  1_555 A U 70 1_555 -0.311 -1.428 2.562 -8.627 4.675  29.477  -3.356 -0.688 2.311 8.882   16.393 
31.033  1  CC_G501G502:U571C572_CC C 501 ? C 572 ? C 502 ? C 571 ? 
1 A G 2  1_555 A U 70 1_555 A C 3  1_555 A G 69 1_555 0.084  -1.151 3.321 2.254  5.503  43.633  -2.052 0.100  3.161 7.362   -3.016 
44.016  2  CC_G502C503:G570U571_CC C 502 ? C 571 ? C 503 ? C 570 ? 
1 A C 3  1_555 A G 69 1_555 A C 4  1_555 A G 68 1_555 0.375  -1.862 3.369 0.055  2.150  32.816  -3.662 -0.654 3.245 3.801   -0.097 
32.884  3  CC_C503C504:G569G570_CC C 503 ? C 570 ? C 504 ? C 569 ? 
1 A C 4  1_555 A G 68 1_555 A C 5  1_555 A G 67 1_555 -0.404 -1.786 3.013 5.341  3.043  31.358  -3.734 1.592  2.728 5.562   -9.763 
31.940  4  CC_C504C505:G568G569_CC C 504 ? C 569 ? C 505 ? C 568 ? 
1 A C 5  1_555 A G 67 1_555 A C 6  1_555 A G 66 1_555 0.300  -1.823 3.257 -2.477 9.037  31.232  -4.694 -0.930 2.610 16.331  4.476 
32.574  5  CC_C505C506:G567G568_CC C 505 ? C 568 ? C 506 ? C 567 ? 
1 A C 6  1_555 A G 66 1_555 A A 7  1_555 A U 65 1_555 -0.950 -1.281 3.329 5.104  14.662 35.292  -3.637 2.032  2.470 22.867  -7.960 
38.456  6  CC_C506A507:U566G567_CC C 506 ? C 567 ? C 507 ? C 566 ? 
1 A A 7  1_555 A U 65 1_555 A G 48 1_555 A C 64 1_555 -2.037 -1.007 3.351 -7.020 -3.066 47.101  -0.981 1.914  3.656 -3.807  8.716 
47.685  7  CC_A507G549:C565U566_CC C 507 ? C 566 ? C 549 ? C 565 ? 
1 A G 48 1_555 A C 64 1_555 A G 49 1_555 A C 63 1_555 -0.723 -1.941 3.139 1.487  2.527  34.004  -3.681 1.452  2.958 4.310   -2.536 
34.127  8  CC_G549G550:C564C565_CC C 549 ? C 565 ? C 550 ? C 564 ? 
1 A G 49 1_555 A C 63 1_555 A G 50 1_555 A C 62 1_555 0.342  -1.399 3.033 -0.641 3.024  30.672  -3.167 -0.756 2.877 5.699   1.208 
30.823  9  CC_G550G551:C563C564_CC C 550 ? C 564 ? C 551 ? C 563 ? 
1 A G 50 1_555 A C 62 1_555 A G 51 1_555 A C 61 1_555 0.430  -1.776 3.293 5.055  9.593  28.225  -5.227 0.133  2.600 18.815  -9.915 
30.197  10 CC_G551G552:C562C563_CC C 551 ? C 563 ? C 552 ? C 562 ? 
1 A G 51 1_555 A C 61 1_555 A G 52 1_555 A C 60 1_555 0.748  -2.116 2.768 -8.634 3.147  32.882  -4.002 -2.357 2.297 5.429   14.894 
34.108  11 CC_G552G553:C561C562_CC C 552 ? C 562 ? C 553 ? C 561 ? 
1 A G 52 1_555 A C 60 1_555 A U 53 1_555 A A 57 1_555 -1.910 -3.019 3.431 0.339  0.661  93.652  -2.082 1.316  3.410 0.453   -0.232 
93.654  12 CC_G553U554:A558C561_CC C 553 ? C 561 ? C 554 ? C 558 ? 
1 A U 53 1_555 A A 57 1_555 A U 54 1_555 A G 17 1_555 1.962  -1.522 3.135 7.852  -2.584 45.147  -1.725 -1.824 3.488 -3.333  
-10.126 45.858  13 CC_U554U555:G518A558_CC C 554 ? C 558 ? C 555 ? C 518 ? 
1 A A 38 1_555 A C 32 1_555 A G 39 1_555 A C 31 1_555 -0.096 -1.152 3.520 1.824  10.756 48.315  -2.207 0.256  3.205 12.950  -2.196 
49.459  14 CC_A538G539:C531C532_CC C 538 ? C 532 ? C 539 ? C 531 ? 
1 A G 39 1_555 A C 31 1_555 A G 40 1_555 A C 30 1_555 0.125  -1.663 3.356 -0.288 7.041  31.714  -4.176 -0.272 2.928 12.688  0.518 
32.467  15 CC_G539G540:C530C531_CC C 539 ? C 531 ? C 540 ? C 530 ? 
1 A G 40 1_555 A C 30 1_555 A C 41 1_555 A G 29 1_555 -0.165 -1.545 3.223 -1.856 3.379  35.580  -2.985 0.011  3.073 5.510   3.026 
35.782  16 CC_G540C541:G529C530_CC C 540 ? C 530 ? C 541 ? C 529 ? 
1 A C 41 1_555 A G 29 1_555 A C 42 1_555 A G 28 1_555 0.232  -1.788 3.256 2.057  6.360  32.598  -4.130 -0.080 2.874 11.183  -3.617 
33.258  17 CC_C541C542:G528G529_CC C 541 ? C 529 ? C 542 ? C 528 ? 
1 A C 42 1_555 A G 28 1_555 A G 43 1_555 A C 27 1_555 0.240  -2.014 3.624 4.836  15.342 30.145  -5.817 0.341  2.364 27.201  -8.574 
34.080  18 CC_C542G543:C527G528_CC C 542 ? C 528 ? C 543 ? C 527 ? 
1 A G 43 1_555 A C 27 1_555 A A 44 1_555 A G 26 1_555 -1.054 -1.363 3.087 1.309  3.845  35.063  -2.770 1.915  2.886 6.355   -2.163 
35.290  19 CC_G543A544:G526C527_CC C 543 ? C 527 ? C 544 ? C 526 ? 
1 A A 44 1_555 A G 26 1_555 A G 10 1_555 A C 25 1_555 -3.012 -2.211 3.201 14.531 13.673 57.498  -2.730 3.557  1.936 13.766  
-14.630 60.581  20 CC_A544G510:C525G526_CC C 544 ? C 526 ? C 510 ? C 525 ? 
1 A G 10 1_555 A C 25 1_555 A U 11 1_555 A A 24 1_555 0.324  -1.891 3.504 0.761  6.048  36.360  -3.834 -0.406 3.166 9.609   -1.209 
36.850  21 CC_G510U511:A524C525_CC C 510 ? C 525 ? C 511 ? C 524 ? 
1 A U 11 1_555 A A 24 1_555 A C 12 1_555 A G 23 1_555 -0.590 -1.710 3.288 0.237  9.841  34.744  -4.067 0.985  2.715 16.085  -0.388 
36.070  22 CC_U511C512:G523A524_CC C 511 ? C 524 ? C 512 ? C 523 ? 
1 A C 12 1_555 A G 23 1_555 A U 13 1_555 A G 22 1_555 1.544  -2.202 2.944 3.604  4.447  27.920  -5.366 -2.413 2.741 9.095   -7.371 
28.489  23 CC_C512U513:G522G523_CC C 512 ? C 523 ? C 513 ? C 522 ? 
1 A U 13 1_555 A G 22 1_555 A A 14 1_555 A U 8  1_555 -1.021 -0.890 3.121 -0.777 -2.920 66.328  -0.701 0.903  3.163 -2.667  0.709 
66.389  24 CC_U513A514:U508G522_CC C 513 ? C 522 ? C 514 ? C 508 ? 
1 A A 14 1_555 A U 8  1_555 A G 15 1_555 A C 47 1_555 1.972  -2.606 3.608 3.152  17.656 -78.838 1.474  1.622  3.959 -13.739 2.453 
-80.527 25 CC_A514G515:C548U508_CC C 514 ? C 508 ? C 515 ? C 548 ? 
1 B G 1  1_555 B C 71 1_555 B G 2  1_555 B U 70 1_555 -0.359 -1.442 2.698 -9.498 4.745  29.267  -3.425 -0.804 2.435 9.025   18.064 
31.094  26 DD_G501G502:U571C572_DD D 501 ? D 572 ? D 502 ? D 571 ? 
1 B G 2  1_555 B U 70 1_555 B C 3  1_555 B G 69 1_555 0.067  -1.074 3.178 4.240  6.168  42.708  -2.026 0.302  2.996 8.392   -5.769 
43.328  27 DD_G502C503:G570U571_DD D 502 ? D 571 ? D 503 ? D 570 ? 
1 B C 3  1_555 B G 69 1_555 B C 4  1_555 B G 68 1_555 0.439  -1.698 3.338 0.386  4.286  33.476  -3.613 -0.694 3.108 7.404   -0.667 
33.744  28 DD_C503C504:G569G570_DD D 503 ? D 570 ? D 504 ? D 569 ? 
1 B C 4  1_555 B G 68 1_555 B C 5  1_555 B G 67 1_555 -0.434 -1.751 3.179 2.691  6.228  30.774  -4.289 1.259  2.734 11.560  -4.995 
31.495  29 DD_C504C505:G568G569_DD D 504 ? D 569 ? D 505 ? D 568 ? 
1 B C 5  1_555 B G 67 1_555 B C 6  1_555 B G 66 1_555 0.314  -1.746 3.320 -1.088 7.880  31.753  -4.396 -0.736 2.805 14.127  1.951 
32.709  30 DD_C505C506:G567G568_DD D 505 ? D 568 ? D 506 ? D 567 ? 
1 B C 6  1_555 B G 66 1_555 B A 7  1_555 B U 65 1_555 -1.007 -1.165 3.254 4.507  14.410 35.473  -3.407 2.041  2.473 22.438  -7.018 
38.457  31 DD_C506A507:U566G567_DD D 506 ? D 567 ? D 507 ? D 566 ? 
1 B A 7  1_555 B U 65 1_555 B G 48 1_555 B C 64 1_555 -1.630 -1.675 3.060 -2.971 -1.535 47.722  -1.949 1.784  3.199 -1.894  3.667 
47.832  32 DD_A507G549:C565U566_DD D 507 ? D 566 ? D 549 ? D 565 ? 
1 B G 48 1_555 B C 64 1_555 B G 49 1_555 B C 63 1_555 -0.722 -2.001 3.143 2.997  1.052  34.089  -3.555 1.672  3.009 1.790   -5.098 
34.233  33 DD_G549G550:C564C565_DD D 549 ? D 565 ? D 550 ? D 564 ? 
1 B G 49 1_555 B C 63 1_555 B G 50 1_555 B C 62 1_555 0.325  -1.422 3.063 -0.867 3.910  31.148  -3.294 -0.749 2.858 7.244   1.605 
31.398  34 DD_G550G551:C563C564_DD D 550 ? D 564 ? D 551 ? D 563 ? 
1 B G 50 1_555 B C 62 1_555 B G 51 1_555 B C 61 1_555 0.382  -1.816 3.265 4.860  8.406  28.291  -5.146 0.198  2.656 16.591  -9.593 
29.879  35 DD_G551G552:C562C563_DD D 551 ? D 563 ? D 552 ? D 562 ? 
1 B G 51 1_555 B C 61 1_555 B G 52 1_555 B C 60 1_555 0.720  -2.171 2.839 -7.132 5.870  32.221  -4.530 -2.177 2.215 10.314  12.532 
33.485  36 DD_G552G553:C561C562_DD D 552 ? D 562 ? D 553 ? D 561 ? 
1 B G 52 1_555 B C 60 1_555 B U 53 1_555 B A 57 1_555 -2.047 -2.967 3.541 -4.109 0.916  94.259  -2.041 1.315  3.585 0.624   2.802 
94.331  37 DD_G553U554:A558C561_DD D 553 ? D 561 ? D 554 ? D 558 ? 
1 B U 53 1_555 B A 57 1_555 B U 54 1_555 B G 17 1_555 1.779  -1.360 3.180 8.395  -3.783 46.306  -1.379 -1.513 3.528 -4.756  
-10.552 47.163  38 DD_U554U555:G518A558_DD D 554 ? D 558 ? D 555 ? D 518 ? 
1 B A 38 1_555 B C 32 1_555 B G 39 1_555 B C 31 1_555 0.071  -0.883 3.490 1.075  12.608 50.504  -1.885 -0.007 3.199 14.517  -1.238 
51.964  39 DD_A538G539:C531C532_DD D 538 ? D 532 ? D 539 ? D 531 ? 
1 B G 39 1_555 B C 31 1_555 B G 40 1_555 B C 30 1_555 0.272  -1.669 3.296 -1.870 7.690  32.152  -4.161 -0.778 2.813 13.629  3.314 
33.086  40 DD_G539G540:C530C531_DD D 539 ? D 531 ? D 540 ? D 530 ? 
1 B G 40 1_555 B C 30 1_555 B C 41 1_555 B G 29 1_555 -0.195 -1.603 3.189 0.624  3.856  35.353  -3.159 0.406  3.000 6.326   -1.023 
35.561  41 DD_G540C541:G529C530_DD D 540 ? D 530 ? D 541 ? D 529 ? 
1 B C 41 1_555 B G 29 1_555 B C 42 1_555 B G 28 1_555 0.299  -1.790 3.179 2.063  7.441  30.966  -4.494 -0.202 2.700 13.672  -3.790 
31.892  42 DD_C541C542:G528G529_DD D 541 ? D 529 ? D 542 ? D 528 ? 
1 B C 42 1_555 B G 28 1_555 B G 43 1_555 B C 27 1_555 0.258  -1.930 3.541 1.592  13.084 30.774  -5.459 -0.192 2.542 23.357  -2.841 
33.415  43 DD_C542G543:C527G528_DD D 542 ? D 528 ? D 543 ? D 527 ? 
1 B G 43 1_555 B C 27 1_555 B A 44 1_555 B G 26 1_555 -1.002 -1.469 3.146 2.692  5.222  34.618  -3.155 2.032  2.818 8.698   -4.484 
35.098  44 DD_G543A544:G526C527_DD D 543 ? D 527 ? D 544 ? D 526 ? 
1 B A 44 1_555 B G 26 1_555 B G 10 1_555 B C 25 1_555 -3.000 -2.489 3.165 14.255 16.159 60.115  -2.925 3.343  1.828 15.600  
-13.762 63.519  45 DD_A544G510:C525G526_DD D 544 ? D 526 ? D 510 ? D 525 ? 
1 B G 10 1_555 B C 25 1_555 B U 11 1_555 B A 24 1_555 0.362  -1.912 3.528 -0.391 2.820  36.004  -3.506 -0.643 3.369 4.554   0.632 
36.113  46 DD_G510U511:A524C525_DD D 510 ? D 525 ? D 511 ? D 524 ? 
1 B U 11 1_555 B A 24 1_555 B C 12 1_555 B G 23 1_555 -0.550 -1.723 3.192 1.414  10.527 35.930  -3.934 1.025  2.581 16.622  -2.233 
37.418  47 DD_U511C512:G523A524_DD D 511 ? D 524 ? D 512 ? D 523 ? 
1 B C 12 1_555 B G 23 1_555 B U 13 1_555 B G 22 1_555 1.531  -2.305 2.959 2.884  3.888  27.272  -5.644 -2.585 2.754 8.164   -6.055 
27.690  48 DD_C512U513:G522G523_DD D 512 ? D 523 ? D 513 ? D 522 ? 
1 B U 13 1_555 B G 22 1_555 B A 14 1_555 B U 8  1_555 -1.066 -0.934 3.124 0.493  -2.925 66.222  -0.742 0.994  3.151 -2.676  -0.451 
66.281  49 DD_U513A514:U508G522_DD D 513 ? D 522 ? D 514 ? D 508 ? 
1 B A 14 1_555 B U 8  1_555 B G 15 1_555 B C 47 1_555 1.894  -2.732 3.689 1.376  18.735 -75.062 1.534  1.569  4.146 -15.151 1.113 
-77.040 50 DD_A514G515:C548U508_DD D 514 ? D 508 ? D 515 ? D 548 ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'MAGNESIUM ION' MG  
4 'GLUTAMIC ACID' GLU 
5 water           HOH 
# 
