ID A0EI04_PARTE Unreviewed; 1069 AA. AC A0EI04; DT 28-NOV-2006, integrated into UniProtKB/TrEMBL. DT 28-NOV-2006, sequence version 1. DT 14-MAY-2014, entry version 22. DE SubName: Full=Chromosome undetermined scaffold_98, whole genome shotgun sequence; GN ORFNames=GSPATT00027272001; OS Paramecium tetraurelia. OC Eukaryota; Alveolata; Ciliophora; Intramacronucleata; OC Oligohymenophorea; Peniculida; Parameciidae; Paramecium. OX NCBI_TaxID=5888; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Stock d4-2; RX PubMed=17086204; DOI=10.1038/nature05230; RG Genoscope; RA Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M., RA Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A., RA Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., RA Guigo R., Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., RA Klotz C., Koll F., Le Mouel A., Lepere G., Malinsky S., Nowacki M., RA Nowak J.K., Plattner H., Poulain J., Ruiz F., Serrano V., Zagulski M., RA Dessen P., Betermier M., Weissenbach J., Scarpelli C., Schaechter V., RA Sperling L., Meyer E., Cohen J., Wincker P.; RT "Global trends of whole-genome duplications revealed by the ciliate RT Paramecium tetraurelia."; RL Nature 444:171-178(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CT868680; CAK94945.1; -; Genomic_DNA. DR RefSeq; XP_001462318.1; XM_001462281.1. DR EnsemblProtists; CAK94945; CAK94945; GSPATT00027272001. DR GeneID; 5048103; -. DR KEGG; ptm:GSPATT00027272001; -. DR KO; K03155; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. DR SUPFAM; SSF48371; SSF48371; 3. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1069 AA; 126590 MW; 2CD01E2E1D7199FA CRC64; MDRDFDSESN FEERLIEDEE RNDQRYYTTQ LLLSIQGLGT FTKVDNMNVY AKGEKAEGAL KHLCQQCKKD IPDKPIARIY LAKYRVFQLN LINLLTCYPQ DKVLSYYVVI LMEQLTNVDR SGIKLQTPNA PQMLDTLQEY KLYFLKPIVL QTLVNHFAEC IQVDQECRTK VHNDMIELIV LLFKNLLSIP DIEETKIGLE SGKEVKRNLQ RNFIYCMIKE SVLSAFIYIS QDFKSSFMQR IALPLMEIFY YALTPFDPEW LLRDSEQEKE LILKQAQQYR LQKQQHLSTI PTRHSRFPGL FVTKRVLSQS GQISSQPFHQ HQVNKLANQR QKPQVRALIS KQKTIFVKPL TIDLYDPEKE KNFKEELRHS TIDFLIHCFS KLIDQAYIEM NKEIVDSDDK VHYFVLISHF LKFIRFHCKQ NKEDNQGQLS SEFVSVQAAL QITQFNFIYS NLINESTQLK KKNFNYRNFF AVINVLFEFL MIVRELSLSV EQTDRRNSQI LLQTIVTQDI AKAISIGYGY CQFGLFNDQM LSTLVKLTAL YYDLLELHTQ GKAWSIRTNK LLKKKIKKQQ NKANRGRKRK QDQPNEEDND FIEKGPDEEH SMREEEEDEE NEEDDDENET EDDQPIYKER RCNFVSEFAI IVDYKVLEKY FYLIKEDKLL RNSSELNIAI YKYFKRIVDT LKADWIFFQL DFLYVINSII QNKQLTYKSE FLNLIQLFRR IGISFVQLFK VNRLMSVEIL FRFPNAATKD SILKNYQDSV AEGGADLENY QQEGPKKKVI WTQKEDKILI ENYEKYKDCE QPEEQLSLLL SQNGFTIKSP AEIRKRIRKF RLEEGNEKAI ALYQQQYEMI SMKKVEIMAK SVKSLLQEVG EESLNQFFNH LFSTLENYVD YRGQESIEMP IPPLDKLQFE FFEKGSVQAI FLGLDLKPPS QGEIYWRLQT HTFRPEINEM RSMLTKYLEK AKKIDDDQII EEFQPLQINS QKKQLDSKKK VIENISAYAE DELDDENEQQ GSDKKVVEKK MKLDKKSKDL DSEEERQIYE KYMEQQAQNE QIQRDVENKS KDNYDDIFD // ID A1YUF1_DROAE Unreviewed; 167 AA. AC A1YUF1; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 16-OCT-2013, entry version 12. DE SubName: Full=Tim; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FP99.05, FP99.13, FP99.29, FP99.35, FP99.71, HI99.11, HI99.15, RC HI99.35, HI99.47, HI99.53, HI99.55, IR04.03, IR04.10, IR04.12, RC IR04.18, IR04.22, IR04.36, IR04.53, IR04.69, IR04.96, SB02.02, RC SB02.06, SB02.07, SB02.08, SB02.09, SB02.10, SB02.11, SB02.13, and RC SB02.15; RX PubMed=17205116; DOI=10.1371/journal.pone.0000112; RA McAllister B.F., Evans A.L.; RT "Increased nucleotide diversity with transient Y linkage in Drosophila RT americana."; RL PLoS ONE 1:E112-E112(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF137129; ABL85402.1; -; Genomic_DNA. DR EMBL; EF137131; ABL85404.1; -; Genomic_DNA. DR EMBL; EF137133; ABL85406.1; -; Genomic_DNA. DR EMBL; EF137134; ABL85407.1; -; Genomic_DNA. DR EMBL; EF137135; ABL85408.1; -; Genomic_DNA. DR EMBL; EF137140; ABL85413.1; -; Genomic_DNA. DR EMBL; EF137141; ABL85414.1; -; Genomic_DNA. DR EMBL; EF137144; ABL85417.1; -; Genomic_DNA. DR EMBL; EF137146; ABL85419.1; -; Genomic_DNA. DR EMBL; EF137147; ABL85420.1; -; Genomic_DNA. DR EMBL; EF137148; ABL85421.1; -; Genomic_DNA. DR EMBL; EF137149; ABL85422.1; -; Genomic_DNA. DR EMBL; EF137151; ABL85424.1; -; Genomic_DNA. DR EMBL; EF137152; ABL85425.1; -; Genomic_DNA. DR EMBL; EF137153; ABL85426.1; -; Genomic_DNA. DR EMBL; EF137154; ABL85427.1; -; Genomic_DNA. DR EMBL; EF137155; ABL85428.1; -; Genomic_DNA. DR EMBL; EF137156; ABL85429.1; -; Genomic_DNA. DR EMBL; EF137157; ABL85430.1; -; Genomic_DNA. DR EMBL; EF137158; ABL85431.1; -; Genomic_DNA. DR EMBL; EF137159; ABL85432.1; -; Genomic_DNA. DR EMBL; EF137160; ABL85433.1; -; Genomic_DNA. DR EMBL; EF137161; ABL85434.1; -; Genomic_DNA. DR EMBL; EF137162; ABL85435.1; -; Genomic_DNA. DR EMBL; EF137163; ABL85436.1; -; Genomic_DNA. DR EMBL; EF137164; ABL85437.1; -; Genomic_DNA. DR EMBL; EF137165; ABL85438.1; -; Genomic_DNA. DR EMBL; EF137166; ABL85439.1; -; Genomic_DNA. DR EMBL; EF137167; ABL85440.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 167 167 SQ SEQUENCE 167 AA; 18720 MW; 100B0664A05E17BD CRC64; VEYMKHILES DPKLSPHKCD QINNCLLLLR NILHIPESHA HFLMPRLQSG GGHQVSMQNT ILWNLFIQSI DKLLLYLMTC PQRSLWGVTM VQLIALIYKD QHVSTLQKLL NLWFEASLSE SSDDNESNTT PPKQASGDSS PMLTSDPTSD SSDNGSGGKK ESCEGRR // ID A1YUF2_DROAE Unreviewed; 167 AA. AC A1YUF2; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 06-FEB-2013, entry version 10. DE SubName: Full=Tim; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FP99.09; RX PubMed=17205116; DOI=10.1371/journal.pone.0000112; RA McAllister B.F., Evans A.L.; RT "Increased nucleotide diversity with transient Y linkage in Drosophila RT americana."; RL PLoS ONE 1:E112-E112(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF137130; ABL85403.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 167 167 SQ SEQUENCE 167 AA; 18702 MW; B6AC0894B0B01572 CRC64; VEYMKHILXS DPKLSPHKCD QINNCLLLLR NILHIPESHA HFLMPRLQSG GGHQVSMQNT ILWNLFIQSI DKLLLYLMTC PQRSLWGVTM VQLIALIYKD QHVSTLQKLL NLWFEASLSE SSDDNESNTT PPKQASGDSS PMLTSDPTSD SSDNGSGGKK ESCEGRR // ID A1YUF4_DROAE Unreviewed; 167 AA. AC A1YUF4; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 16-OCT-2013, entry version 12. DE SubName: Full=Tim; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FP99.27, FP99.81, FP99.85, HI99.03, HI99.21, HI99.31, IR04.04, RC and SB02.17; RX PubMed=17205116; DOI=10.1371/journal.pone.0000112; RA McAllister B.F., Evans A.L.; RT "Increased nucleotide diversity with transient Y linkage in Drosophila RT americana."; RL PLoS ONE 1:E112-E112(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF137132; ABL85405.1; -; Genomic_DNA. DR EMBL; EF137136; ABL85409.1; -; Genomic_DNA. DR EMBL; EF137137; ABL85410.1; -; Genomic_DNA. DR EMBL; EF137139; ABL85412.1; -; Genomic_DNA. DR EMBL; EF137142; ABL85415.1; -; Genomic_DNA. DR EMBL; EF137143; ABL85416.1; -; Genomic_DNA. DR EMBL; EF137150; ABL85423.1; -; Genomic_DNA. DR EMBL; EF137168; ABL85441.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 167 167 SQ SEQUENCE 167 AA; 18750 MW; B00B1264AF33BA0B CRC64; VEYMKHILES DPKLSPHKCD QINNCLLLLR NILHIPESHA HFLMPRLQSG SGHQVSMQNT ILWNLFIQSI DKLLLYLMTC PQRSLWGVTM VQLIALIYKD QHVSTLQKLL NLWFEASLSE SSDDNESNTT PPKQASGDSS PMLTSDPTSD SSDNGSGGKK ESCEGRR // ID A1YUG0_DROAE Unreviewed; 167 AA. AC A1YUG0; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 06-FEB-2013, entry version 10. DE SubName: Full=Tim; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=FP99.91; RX PubMed=17205116; DOI=10.1371/journal.pone.0000112; RA McAllister B.F., Evans A.L.; RT "Increased nucleotide diversity with transient Y linkage in Drosophila RT americana."; RL PLoS ONE 1:E112-E112(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF137138; ABL85411.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 167 167 SQ SEQUENCE 167 AA; 18703 MW; 100B1E28248E17BD CRC64; VEYMKHILES DPKLSPHKCD QINNCLLLLR NILHIPESHA HFLMPRLQSG GGHQVSMQNT ILWNLFIQSI DKLLLYLMTC PQRSLWGVTM VQLIALIYKD QHVSTLQKLL NLWFEASLSE SSDDNESNTT PPXQASGDSS PMLTSDPTSD SSDNGSGGKK ESCEGRR // ID A1YUG7_DROAE Unreviewed; 167 AA. AC A1YUG7; DT 06-FEB-2007, integrated into UniProtKB/TrEMBL. DT 06-FEB-2007, sequence version 1. DT 06-FEB-2013, entry version 10. DE SubName: Full=Tim; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=HI99.41; RX PubMed=17205116; DOI=10.1371/journal.pone.0000112; RA McAllister B.F., Evans A.L.; RT "Increased nucleotide diversity with transient Y linkage in Drosophila RT americana."; RL PLoS ONE 1:E112-E112(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF137145; ABL85418.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 167 167 SQ SEQUENCE 167 AA; 18702 MW; 100B0675505E17BD CRC64; VEYMKHILES DPKLSPHKCD QINNCLLLLR NILHIPESHA HFLMPRLQSG GGHQVSMQNT ILWNLFIQSI DKLLLYLMTC PQRSLWGVTM VQLIALIYKD QHVSTLQKLL NLWFEASLSE SSDDNESNTT PPKQASGDSS PMLTSDPTSD SSDNGSGGKK ESCXGRR // ID A2DDT2_TRIVA Unreviewed; 770 AA. AC A2DDT2; DT 20-FEB-2007, integrated into UniProtKB/TrEMBL. DT 20-FEB-2007, sequence version 1. DT 18-SEP-2013, entry version 19. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=TVAG_198970; OS Trichomonas vaginalis. OC Eukaryota; Parabasalia; Trichomonadida; Trichomonadidae; Trichomonas. OX NCBI_TaxID=5722; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC PRA-98 / G3; RX PubMed=17218520; DOI=10.1126/science.1132894; RA Carlton J.M., Hirt R.P., Silva J.C., Delcher A.L., Schatz M., Zhao Q., RA Wortman J.R., Bidwell S.L., Alsmark U.C.M., Besteiro S., RA Sicheritz-Ponten T., Noel C.J., Dacks J.B., Foster P.G., Simillion C., RA Van de Peer Y., Miranda-Saavedra D., Barton G.J., Westrop G.D., RA Mueller S., Dessi D., Fiori P.L., Ren Q., Paulsen I., Zhang H., RA Bastida-Corcuera F.D., Simoes-Barbosa A., Brown M.T., Hayes R.D., RA Mukherjee M., Okumura C.Y., Schneider R., Smith A.J., Vanacova S., RA Villalvazo M., Haas B.J., Pertea M., Feldblyum T.V., Utterback T.R., RA Shu C.L., Osoegawa K., de Jong P.J., Hrdy I., Horvathova L., RA Zubacova Z., Dolezal P., Malik S.B., Logsdon J.M. Jr., Henze K., RA Gupta A., Wang C.C., Dunne R.L., Upcroft J.A., Upcroft P., White O., RA Salzberg S.L., Tang P., Chiu C.-H., Lee Y.-S., Embley T.M., RA Coombs G.H., Mottram J.C., Tachezy J., Fraser-Liggett C.M., RA Johnson P.J.; RT "Draft genome sequence of the sexually transmitted pathogen RT Trichomonas vaginalis."; RL Science 315:207-212(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS113190; EAY21458.1; -; Genomic_DNA. DR RefSeq; XP_001582444.1; XM_001582394.1. DR GeneID; 5467006; -. DR KEGG; tva:TVAG_198970; -. DR EuPathDB; TrichDB:TVAG_198970; -. DR eggNOG; NOG281055; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 770 AA; 87881 MW; A793F4195261E1B4 CRC64; MQANEARISE LANNLGRQVD DEYIEFDDCK INLEELAYSI WTEDNIQKPI TKQIFDLRTF ETHFCPLLLS ESPDLSFIAL KALASCTYPY PANANDIEIL NNIYQHYKRV LTFKKDVLLT ALEFVHSIII DPHASQEDFQ KAEVGFTFIR NVLVIPSPSD VSESLFHILN EGGLYEIIEV LKIKSFGSRI KKFAQILAGI LYGSFVPFLP LTTTEEEPKQ EVVPNSPKKP SPLDALASQL KSQKLNKPSR HGHWGGSLLV KSSTKGFVYN GPITSEVIDK GVDPTSIIKP HSRRNIIESR EIPPQFTPEV QEAARRLIGT DSFKYVFSRV LPRSFSAYDA TISITEQIQM VDLTRFYLEF ILKYGGQFSV RPLVSEENIK YFLTMANFYM DARVANLDAT PLNKALNKVC LLFGYAAKFL VDVIMKSLDG EEIKAAKSIV TESATDIEDF LITVLSKKLK SNSPVYMLQD AIISLERLLQ LYKVAETEKM VRKRTYGDST STADEFDEIF VDYEAFDAEA IIKRLTRRTN VLDPYFTCIE NWRKCNQEEL GSIAKMLKRF VFKRSGLSHL FKLTYFIIIN KVLTDKDFQK SEEPEIIELR EVMHSIINKF LYNVKRQKST LLLILVGPDS DELFDEVDDM ALDDDEMFDA LGVSQEVRDI MRDVPSQPKI RKLRKVHESG YSSEAEDDKQ NLNDEDDDDD KDLESSNDEA DVRTSMETLK REILESKAQN SQSSQSSQVL RKLTSQKADS EDSDDDHLSD EDTKLSDELE // ID A4IE79_DROME Unreviewed; 103 AA. AC A4IE79; DT 01-MAY-2007, integrated into UniProtKB/TrEMBL. DT 01-MAY-2007, sequence version 1. DT 16-OCT-2013, entry version 18. DE SubName: Full=Timeless; DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=timeless; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=BOR15, BOR39, BOR47, CAV21, CAV3, CAV35, CAV4, HER103a, HER2, RC HU151a, W12, and W17; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AM503548; CAM59649.1; -; Genomic_DNA. DR EMBL; AM503549; CAM59650.1; -; Genomic_DNA. DR EMBL; AM503560; CAM59661.1; -; Genomic_DNA. DR EMBL; AM503561; CAM59662.1; -; Genomic_DNA. DR EMBL; AM503562; CAM59663.1; -; Genomic_DNA. DR EMBL; AM503563; CAM59664.1; -; Genomic_DNA. DR EMBL; AM503564; CAM59665.1; -; Genomic_DNA. DR EMBL; AM503565; CAM59666.1; -; Genomic_DNA. DR EMBL; AM503566; CAM59667.1; -; Genomic_DNA. DR EMBL; AM503567; CAM59668.1; -; Genomic_DNA. DR EMBL; AM503568; CAM59669.1; -; Genomic_DNA. DR EMBL; AM503569; CAM59670.1; -; Genomic_DNA. DR Bgee; A4IE79; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 103 103 SQ SEQUENCE 103 AA; 11858 MW; 7D5E727D2E7551EE CRC64; MSRVRQLHNH IWNNQNFDKV KSVMDWLLAT PQLYSAFSSL GCLEGDTYVV NPNALAILEE INYKLTYEDQ TLRTFRRAIG FGQNVRSDLI PLLENAKDDA VLE // ID A4IE81_DROME Unreviewed; 80 AA. AC A4IE81; DT 01-MAY-2007, integrated into UniProtKB/TrEMBL. DT 01-MAY-2007, sequence version 1. DT 16-OCT-2013, entry version 16. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=timeless; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=BOR17, BOR31, CAV17, CAV69, HER, HER14a, HER19a, W13a, W14a, RC and W6a; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AM503550; CAM59651.1; -; Genomic_DNA. DR EMBL; AM503551; CAM59652.1; -; Genomic_DNA. DR EMBL; AM503552; CAM59653.1; -; Genomic_DNA. DR EMBL; AM503553; CAM59654.1; -; Genomic_DNA. DR EMBL; AM503554; CAM59655.1; -; Genomic_DNA. DR EMBL; AM503555; CAM59656.1; -; Genomic_DNA. DR EMBL; AM503556; CAM59657.1; -; Genomic_DNA. DR EMBL; AM503557; CAM59658.1; -; Genomic_DNA. DR EMBL; AM503558; CAM59659.1; -; Genomic_DNA. DR EMBL; AM503559; CAM59660.1; -; Genomic_DNA. DR Bgee; A4IE81; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 80 80 SQ SEQUENCE 80 AA; 9025 MW; EAFF468BB2FE49EC CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE // ID A4RT22_OSTLU Unreviewed; 611 AA. AC A4RT22; DT 15-MAY-2007, integrated into UniProtKB/TrEMBL. DT 15-MAY-2007, sequence version 1. DT 14-MAY-2014, entry version 24. DE SubName: Full=Circadian rhythm control Timeless-like protein; GN Name=Tim; ORFNames=OSTLU_119499; OS Ostreococcus lucimarinus (strain CCE9901). OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales; OC Ostreococcus. OX NCBI_TaxID=436017; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CCE9901; RX PubMed=17460045; DOI=10.1073/pnas.0611046104; RA Palenik B., Grimwood J., Aerts A., Rouze P., Salamov A., Putnam N., RA Dupont C., Jorgensen R., Derelle E., Rombauts S., Zhou K., Otillar R., RA Merchant S.S., Podell S., Gaasterland T., Napoli C., Gendler K., RA Manuell A., Tai V., Vallon O., Piganeau G., Jancek S., Heijde M., RA Jabbari K., Bowler C., Lohr M., Robbens S., Werner G., Dubchak I., RA Pazour G.J., Ren Q., Paulsen I., Delwiche C., Schmutz J., Rokhsar D., RA Van de Peer Y., Moreau H., Grigoriev I.V.; RT "The tiny eukaryote Ostreococcus provides genomic insights into the RT paradox of plankton speciation."; RL Proc. Natl. Acad. Sci. U.S.A. 104:7705-7710(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP000582; ABO94683.1; -; Genomic_DNA. DR RefSeq; XP_001416390.1; XM_001416353.1. DR STRING; 436017.A4RT22; -. DR GeneID; 5000080; -. DR KEGG; olu:OSTLU_119499; -. DR eggNOG; NOG297449; -. DR HOGENOM; HOG000264570; -. DR OMA; QRTISAD; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 611 AA; 68917 MW; 0A00F0E28C583B62 CRC64; MSKYSEAHLL SLVSTIGVRT TRGGYRKDPE CDASLQDITR FLQKDSSERG VFLQLIAWNV LGKDLLPLLG THCGELSTSF LVVKLLVFLT LPPEKESTNF IAQNQALNST LRVLLDHACI FPKLMLLVSE ALGKLETGNL ENGETLTKIL QLTFTLVRNL LLIARSHSLV GSKSSNVRHE LFRLLLKCQF MEVLSAVIQD ACVSPINNDL PLLVEIFALI LCFHENDSNT STHLNMGTHS AKSAQWSRKL SKFGISKAVK GAVRGGFSGV YVKHSEYAES ERLLRGNPIE THYMSRACGI LIPSTSSTSE LQPWQVGLLT NLSAPVVNQF LFSAWDDLKR SKQMMISSVE HTIRCTNYVQ LCLFFVDIFH SKLASGTAEE VVLKNPVASI LCADFLIWIQ KEWFEFEQNK SLQECIPLIE LLASIATTLK SLQVKSADST VQLACKAMRS AYVHGESKHE FVRLLRTRIK QFKWLSMPAP YLRALFLLHG AIYELLADDN PNSVSHDVRE QLREFLVDRI IVENHVGLMY RCESRNERET KYRVEFLKQL ASSTVFRLST LLSLRRLEKG HRDISTASKE LCLKAVKQLC RDGVRNPEGW KGSVFINLLA W // ID A6QQJ4_BOVIN Unreviewed; 532 AA. AC A6QQJ4; DT 21-AUG-2007, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 1. DT 22-JAN-2014, entry version 20. DE SubName: Full=TIMELESS protein; GN Name=TIMELESS; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=L1 Hereford; TISSUE=Ascending colon; RA Moore S., Alexander L., Brownstein M., Guan L., Lobo S., Meng Y., RA Tanaguchi M., Wang Z., Yu J., Prange C., Schreiber K., Shenmen C., RA Wagner L., Bala M., Barbazuk S., Barber S., Babakaiff R., Beland J., RA Chun E., Del Rio L., Gibson S., Hanson R., Kirkpatrick R., Liu J., RA Matsuo C., Mayo M., Santos R.R., Stott J., Tsai M., Wong D., RA Siddiqui A., Holt R., Jones S.J., Marra M.A.; RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BC149863; AAI49864.1; -; mRNA. DR UniGene; Bt.22067; -. DR STRING; 9913.ENSBTAP00000027263; -. DR eggNOG; NOG328380; -. DR HOVERGEN; HBG099504; -. DR NextBio; 20873613; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 532 AA; 61347 MW; CCA46030D775508C CRC64; MMNCELLATC SALGYLEGDT YHKEPDCLES VKDLIRYLRH EDETRDVRQQ LGSAQILQSD LLPILTQHRQ DKPLFDAVIR LMVNLTQPAL LCFGSVPKEP SFRHHFLQVL AYLQAYKEAF ASEKAFGVLS ETLYELLQLG WEERQEEDNL LIERILLLVR NVLHVPADLE QEKRIDDDAS VHDRLLWAIH LSGLDDLLLF LASSPAEQQW SLHVLEIISL MFRDQNPEQL AGVGQGRLAQ ERRTDVAELE VLRQREMAEK KTRALQRGNR HSRFGGSYII QGLKSIGERD LVFHKGLHNL QNYTSDLGKQ PRRVPKRRQA ARELSIQRRS ALNVRLFLRD FCSEFLENCY NRLMGSVKDH LLREKAQQHD ETYYMWSLAF FMAFNRAASF RPGLVSETLS VRTFHFIEQN LTNYYEMMLT DRKEAVSWAR RMHLALKAYQ ELLATVNEMD VCPDEAVRES SRIIKSEAWP GCWSRLPCLS TQTSPFPSQL HLSPPSPSFP DQSFHPLLFS VCRQHFLCDG VPGALPGSLS EV // ID A6RDL6_AJECN Unreviewed; 1059 AA. AC A6RDL6; DT 21-AUG-2007, integrated into UniProtKB/TrEMBL. DT 21-AUG-2007, sequence version 1. DT 22-JAN-2014, entry version 17. DE SubName: Full=Predicted protein; GN ORFNames=HCAG_07724; OS Ajellomyces capsulatus (strain NAm1 / WU24) (Darling's disease fungus) OS (Histoplasma capsulatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=339724; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NAm1 / WU24; RX PubMed=19717792; DOI=10.1101/gr.087551.108; RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., RA Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., RA Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., RA Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J., RA Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.; RT "Comparative genomic analyses of the human fungal pathogens RT Coccidioides and their relatives."; RL Genome Res. 19:1722-1731(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH476663; EDN11271.1; -; Genomic_DNA. DR RefSeq; XP_001537415.1; XM_001537365.1. DR GeneID; 5443759; -. DR KEGG; aje:HCAG_07724; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1059 AA; 121803 MW; 3EB6BBB2323774BA CRC64; MEPESIQSGQ VVDPEVRAYV YNLVSALGGS GSSNTGKYVL GDDALACLRD IKKWLKFYDE KANRMDVASQ MTVNHHRHIP YLQHSQVLYK RGILGNDATA TLRTIIRIAL PSMTTPRSDR SSRDEGILKL MLYLFRNIAI VTPSHLTAEG DEEEASKSAT INVFQQQDVF ALLLAMCSSI GEDFIYQDVV ILEILFHIVK GVDIKKLFMN DTQRNIAGTD DLEALLDKES HLKREYAKTA PTRHGRFGTM IWVKRDDEKV STVSGQDVLK DDWTTMLKMD KSKKWDRPKH RKGDIDTSVN NFNVPSPLTP LATKHLRTFV EEFLDSGFNP LFSHIRKAIE READRVTEST PRHFFYVVAW FLEAERARRT RQQEIRQQNA HPSRDFEPDG FQLVASVLNQ ETFIALTRHM QNCLDFKDWQ DLNASMRCFT QILLTVQQML HSDIAEDQDI AENILSRIFY EETTHDKILA ILRVYESQGF WYLDACTELA HVFFRLLEQY SKQNEYMQIR SRRRARRKQR KKAAPNPENG EAQDGDESEA EDLTMEDATK TIVERSFNFQ RFAAKFCTQN SVNTFLALTA YYRELNEEQL KRAHRFFYRV AFKQELSVLL FRVDIISLFY KMIKGPRGLD STKPIYVEWE ELTRRIIRKL VKKLEERPEL ITEILFSKIN ATVFYLEYGH ERQTLSQSKA AAELEVKPGA ANTLDSKLGI VVAALLLEGK ESLVQWLIKT IDTAVNERRS WELEAEARRS ESGEERTANT PPSIAVIPFD DACRTAMFKN GRLRLLMTSA GLERLGVEDT LGSSWIIPSS LSARTLEETK KSIEKHKENP PTEFDGLEPR DLLRRKRDID TTLSHQRTSG EVDFGNDSEG EDDIDDVLFP PNLRTRADTL DERKKKRLRR GKKNGKDGDV LDEASLEARR LARHATALER QRKIKSSLYI HASDEESDEE ADREFFAREE ERRRNQAIRI KQALLSDTTG GDDLPDQNSS TKARKRKGTA DEDEVNKRRR NDHLLPDSDE EVDLTSIDGH QDHDEENSLM VTKDEPSSSS ETTSMSFGW // ID A6ZRH1_YEAS7 Unreviewed; 1238 AA. AC A6ZRH1; DT 11-SEP-2007, integrated into UniProtKB/TrEMBL. DT 11-SEP-2007, sequence version 1. DT 16-APR-2014, entry version 16. DE SubName: Full=Topoisomerase I-interacting factor; GN Name=TOF1; ORFNames=SCY_4532; OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=307796; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=YJM789; RX PubMed=17652520; DOI=10.1073/pnas.0701291104; RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z., RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., RA Wang X., Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., RA Li Y., Davis R.W., Steinmetz L.M.; RT "Genome sequencing and comparative analysis of Saccharomyces RT cerevisiae strain YJM789."; RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAFW02000067; EDN62553.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1238 AA; 141250 MW; 294ABF24CAF2455F CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEDDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGIL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDATYFK DLDNNASDEL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTNLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID A7E5U8_SCLS1 Unreviewed; 1112 AA. AC A7E5U8; DT 11-SEP-2007, integrated into UniProtKB/TrEMBL. DT 11-SEP-2007, sequence version 1. DT 13-NOV-2013, entry version 20. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SS1G_00673; OS Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White OS mold) (Whetzelinia sclerotiorum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes; OC Helotiales; Sclerotiniaceae; Sclerotinia. OX NCBI_TaxID=665079; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 18683 / 1980 / Ss-1; RX PubMed=21876677; DOI=10.1371/journal.pgen.1002230; RA Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., RA Couloux A., Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., RA Fournier E., Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., RA Pradier J.-M., Quevillon E., Sharon A., Simon A., ten Have A., RA Tudzynski B., Tudzynski P., Wincker P., Andrew M., Anthouard V., RA Beever R.E., Beffa R., Benoit I., Bouzid O., Brault B., Chen Z., RA Choquer M., Collemare J., Cotton P., Danchin E.G., Da Silva C., RA Gautier A., Giraud C., Giraud T., Gonzalez C., Grossetete S., RA Gueldener U., Henrissat B., Howlett B.J., Kodira C., Kretschmer M., RA Lappartient A., Leroch M., Levis C., Mauceli E., Neuveglise C., RA Oeser B., Pearson M., Poulain J., Poussereau N., Quesneville H., RA Rascle C., Schumacher J., Segurens B., Sexton A., Silva E., Sirven C., RA Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O., RA Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.; RT "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia RT sclerotiorum and Botrytis cinerea."; RL PLoS Genet. 7:E1002230-E1002230(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH476621; EDN91270.1; -; Genomic_DNA. DR RefSeq; XP_001598584.1; XM_001598534.1. DR STRING; 665079.A7E5U8; -. DR EnsemblFungi; EDN91270; EDN91270; SS1G_00673. DR GeneID; 5494462; -. DR KEGG; ssl:SS1G_00673; -. DR eggNOG; NOG328380; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1112 AA; 126943 MW; 096C3FC9BA5D733D CRC64; MEFSGGKRDV VDPEVRAYVN SLVTALGGSG ADEDGRYVLG DDALACLRDL KKWLKLYDEK ANRLDVARCL AESNLVGGDL LQILAAWPEN ATDDRLKSKI ALACLEVLVP LTWPLEKNKE MTVNHHRHIP YLEIAQVGYK RSILGFDGAR ILHTAVRCAL PAMAEDIGDR STRDQGIIKL LLYFLRNIAM ISPPPNGQYE GDEAEISRSA TIDAFDYQDI FHLLLTLSST MGEDFNTQDV VVMDVIFHLI KGVDVEKLFF SEKAMDNSKT DELIRLRKKE QAMLRSYQTN APTRHNRFGT MAWMQRDDAK MTTISGQAAL RTGRGGLDKM DSTKKFKPPR RAVKGESGPL AFDNPVPLNA SATKNLRAFV EEFLDSGFNP LFTHIRKAID REAERVLDYH HRQFFYLISW FLEAERVRRK NKKPSKAKVP EEVDSFALVA SVLNQEMFIT LNRAMDFNYE NKNWYDLSAG MKCFTQILLT VHEMADSRLE DDQEIAENIL ARIFYEDTTH DRVAMITRTY KDQGFGYLDS CTELTHNYMR ILEQYSKQNV DMQVRSRRRT RTKKKAAIDA GEDQGDDNIV DESEGDDEAR AQKESSERKF DYKRFAAKFL SQGCIDTFVS FTKFYLDLKP AQLKRAHRFF YRVAFKQDMS VMLFRVDIIH LFYMMIKGPG GLDPQSPCYK EWDEMVKQLL KKCTRKIQER PELVVEMLFS KTNSTAHFIE YGYVKQTIAA NPRAAAELEV KGGLEWEDQI GVAVGALLDR NEADHIEWVK SQLSSAESER RSWEAANQAL QSVEKDPFAE DEETPAAEVE PPKAPTILLN PDNDDRKKAM FKNGYLRLLM KLVGLTHFGA ADDPDTSWIV PSSKSADQIK EALDLVKKFE FAPPTFDDDK GALDQIRRVS AGMNRKRAVF DDESDDGIDD DEEELLFEPG GPTAVKKSDA LKALKKNRRR RRNEGSKEPE SRGLTNEQIE ARAAARRARE LEKNRKIKSE LYVRDSDEDD EENDRIFFEA EERLRQKNKI NIMKELLGVG QQKENGKKRM AEKEALETDT PISSPHRSAQ PKRRKVSSDD DESLKKKATE IDDEDEGNIV PVANPRRPRV RAGFIMDSSD DE // ID A7RHY6_NEMVE Unreviewed; 1115 AA. AC A7RHY6; DT 02-OCT-2007, integrated into UniProtKB/TrEMBL. DT 02-OCT-2007, sequence version 1. DT 11-JUN-2014, entry version 33. DE SubName: Full=Predicted protein; DE Flags: Fragment; GN ORFNames=v1g81863; OS Nematostella vectensis (Starlet sea anemone). OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria; OC Edwardsiidae; Nematostella. OX NCBI_TaxID=45351; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CH2 X CH6; RX PubMed=17615350; DOI=10.1126/science.1139158; RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., RA Salamov A., Terry A., Shapiro H., Lindquist E., Kapitonov V.V., RA Jurka J., Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., RA Finnerty J.R., Technau U., Martindale M.Q., Rokhsar D.S.; RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and RT genomic organization."; RL Science 317:86-94(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS469511; EDO48937.1; -; Genomic_DNA. DR RefSeq; XP_001641000.1; XM_001640950.1. DR UniGene; Nve.8578; -. DR STRING; 45351.JGI81863; -. DR EnsemblMetazoa; EDO48937; EDO48937; NEMVEDRAFT_v1g81863. DR GeneID; 5521315; -. DR KEGG; nve:NEMVE_v1g81863; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000133002; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 2. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1115 1115 SQ SEQUENCE 1115 AA; 129494 MW; 1392D04BB8CD50A8 CRC64; MNQYLNTEIV CTLAGLGCAE GTEYYKSPDC LESLKDLIKF LRRDDSTCEI RRQLGNSKVL ENDLIAIVKS CTPKEQDIFD MVIRLMVNLT QPAALCFEHG KIPEDKTGQH YYLELVNQLQ SYKEAFTDKE AMAVIGRELS RTLQKDWDDR QEEDYLLIER VLLLIRNILH VPANPQAEKR TDDDASIHDQ VVWGLHQNGV DDLLLYIASS PDERRWCMHT LEIISLMLRE QNPESLARAG DSRSKSEKSE DVRQLETIRE RELAEKKKNA KKFSGRHSRF GGTFYINNMM SIADKRQMIY HHSVADAKNL TFDREKSAPR KRKNQIIAKE MTVERRSTLS IRLFLQGFCK QFLEHCYNPL LYVVRDNLMH ERSQENDESY FLWAMKFFME FTRHFDFRVD FVGETMSVSN FQYVLKILMQ YYDSFVEDKQ NPVTWGRRLH LAVQAYKELL MYVLFMEKSN DETLRSNAKV IKANIFYMVE YRDVFLFLVR KFDKSKQSKA YLRDLVETFH VFLKMLEDYC SGKSHIVIQQ KKKKKKTKKR KSKQAPARVN LSAEQADEMW QAMASELSSW IQGHNGTIPE SVVPFDAASD IPIDQQRVSA LSRIQTQLQN CEYGESIALL RAAREVWPND SFGAADGDPE DEFMCLHDIF KMTDLPIETT PLADAEAEVN EEEILQLVES KFISLSCWKF PNFLSYSRLA CPSILQPYCW LLGFYRENSA KTNHYLVKML HRVAVDLKIV PMMFQLSLFV TFNRVLHDPA ASQYKEMVKF ARYILGNFFE MLPKNPVLCV ELSTWKTTDA CYEISEGYGS LQNRRSLKKS GATWSYEEEE ELKSLYHQYQ EGEDDVIDKI LDNLQDDTRT RRQIINKLFL LGLVTDKRAF RKPAAKKGAW GADEEEQLRA VYEEYKQSDG DIVEKILSHL TNTSRSRRQV VNQLVKMGLV EDRKTLRKKR KPGEKRGTLR DEGEEDASDY LSSSSDSESD NESLDQTSVP TLVSSLKDCG NIYLIEYVNR EPDIALSTFL FASGLQEQLE WIQSQLRRVA EDREDGDNWQ AYPLVTITEE NEEALSNSQF RAMLKKIGLV PPVTGQQTFW RIPIGMRPAQ LRQAADELEG KRHTE // ID A7TF75_VANPO Unreviewed; 1278 AA. AC A7TF75; DT 02-OCT-2007, integrated into UniProtKB/TrEMBL. DT 02-OCT-2007, sequence version 1. DT 13-NOV-2013, entry version 19. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=Kpol_2000p68; OS Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294) OS (Kluyveromyces polysporus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; OC Vanderwaltozyma. OX NCBI_TaxID=436907; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 22028 / DSM 70294; RX PubMed=17494770; DOI=10.1073/pnas.0608218104; RA Scannell D.R., Frank A.C., Conant G.C., Byrne K.P., Woolfit M., RA Wolfe K.H.; RT "Independent sorting-out of thousands of duplicated gene pairs in two RT yeast species descended from a whole-genome duplication."; RL Proc. Natl. Acad. Sci. U.S.A. 104:8397-8402(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS480382; EDO19100.1; -; Genomic_DNA. DR RefSeq; XP_001646958.1; XM_001646908.1. DR STRING; 436907.A7TF75; -. DR GeneID; 5547429; -. DR KEGG; vpo:Kpol_2000p68; -. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1278 AA; 146841 MW; 271F13DEC4449F4D CRC64; MEQDAEVVAP QTILRARIAL LSTAIGGPDY NSKLVPPPYK LGDDCLACLK DLKRWFKLVD DQQNRWDVAM ATAEYKILVD DLLPILIDWE NKCSLAAKLN KQSGGSGNET VSQNNHFKNK AYHDKIALNC LQLLVLMTWP LVLTDQSTSD QVNFYSDLKK HQLIYKKAIL TMENGKTLKA VLRLAFDVIK LDRLHRTARD NMVLKLVLHF FRNVIAIEPG ELTITTKKRS NKGINTTDTL PPNISLDDIS LDATINSFHR NKVFNLFLTM GSSISTEFDQ DFINLPLLEI MFYLTKDVNQ TKLLTTGKRD NKDLNEKDND RNDNRHLTIT GVELSDLLKK EHQLKKHMIQ NTSSRHSRFG ALLSIKTPDN GRLTVSGGQS LHNDGMALQK LDNRKKWNKR VMQDRDNLII EGLPNNLLNS NSNAAVLHEQ TRKHFRKFVE YFIDSSFDNL LKSITNHFTT EQDRMVSLEQ IEYLLFFSWF VKFQRLRCQI NKDSKLSDIS SVYNETSFIL MCSLLRSSYD EKNWIVLHAS MIAFNEFLIF TYDSKDSDDV EEIEYILSRL FSDDRIQLLT NLPKIASKHS VNFMKAAITL THSVLKTLQE YSEDENGLVV EGKKRRKKKS NNFATEDIQN AMETYDIGRD EALEMLSSST ASVQVNFKRV QNSYMTESVM DTYVKFLERF RELDDDSIKK VFSFFYRVSV DAREESLLFR IDLIILLRDL LSNDGVPRMY KSRKHIDNFT EYLLSKLKKR LKESPAWYVA ILFPSLHDSE VGYYQKYCEK RQSKKDTFHG APPSYFRSIP DQESLEPAAL KDIHVGILVS TLIDDGKLEL IEKLVQNLSK TIDIFKSWIS VNVNDGNDLQ NPPNEIFNSN DDNLKEALIL DKDFRALLQL VGYKIPLNRE DTCYLPGDLD VVQLSEYLSM IEKYMSTPFQ TPNGQPSSSY LVRPKANRQF NNIDDEDGWL SNEEYDYNED GIVRDEDADA NEDNDYFKDL DSMKERTEGR NMSKGLAKSK KKSKSKKKTS KSNLPSFDID NDDTTGRKKH RLTISSKEFI SDSEDENDDI NPIFFENEMY MRWLLDKHNG QLPEEKFALF GKFTSERIAN SGSIINDYSS LFGGAIPDIS SIGNNQNSST QPDRSLISFS NKIDTPPVRT ENSQLSNDEN ITKMMPEMNN KDSSDEEIED LSNLDTDLSD DDVNNSDDNS SLSSNEDTEA TEITRTDRTS IETSVTEQDM NDNLVTGKLI SKRSHERNYS DDEESMEDIS IPRKKARILM DVDDDDDE // ID A7UGV9_DROAE Unreviewed; 172 AA. AC A7UGV9; DT 02-OCT-2007, integrated into UniProtKB/TrEMBL. DT 02-OCT-2007, sequence version 1. DT 16-OCT-2013, entry version 10. DE SubName: Full=Timeless; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=IR04.03 F1, IR04.10 F1, IR04.109 F1, IR04.110 F1, IR04.116 F1, RC IR04.118 F1, IR04.122 F1, IR04.134 F1, IR04.15 F1, IR04.18 F1, RC IR04.20 F1, IR04.22 F1, IR04.25 F1, IR04.34 F1, IR04.36 F1, RC IR04.69 F1, and IR04.96 F1; RX PubMed=17660565; DOI=10.1534/genetics.107.073932; RA Evans A.L., Mena P.A., McAllister B.F.; RT "Positive selection near an inversion breakpoint on the neo-X RT chromosome of Drosophila americana."; RL Genetics 177:1303-1319(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU069267; ABS88332.1; -; Genomic_DNA. DR EMBL; EU069268; ABS88333.1; -; Genomic_DNA. DR EMBL; EU069269; ABS88334.1; -; Genomic_DNA. DR EMBL; EU069270; ABS88335.1; -; Genomic_DNA. DR EMBL; EU069271; ABS88336.1; -; Genomic_DNA. DR EMBL; EU069272; ABS88337.1; -; Genomic_DNA. DR EMBL; EU069273; ABS88338.1; -; Genomic_DNA. DR EMBL; EU069274; ABS88339.1; -; Genomic_DNA. DR EMBL; EU069276; ABS88341.1; -; Genomic_DNA. DR EMBL; EU069277; ABS88342.1; -; Genomic_DNA. DR EMBL; EU069278; ABS88343.1; -; Genomic_DNA. DR EMBL; EU069279; ABS88344.1; -; Genomic_DNA. DR EMBL; EU069280; ABS88345.1; -; Genomic_DNA. DR EMBL; EU069281; ABS88346.1; -; Genomic_DNA. DR EMBL; EU069282; ABS88347.1; -; Genomic_DNA. DR EMBL; EU069283; ABS88348.1; -; Genomic_DNA. DR EMBL; EU069284; ABS88349.1; -; Genomic_DNA. DR EMBL; EU069285; ABS88350.1; -; Genomic_DNA. DR EMBL; EU069286; ABS88351.1; -; Genomic_DNA. DR EMBL; EU069287; ABS88352.1; -; Genomic_DNA. DR EMBL; EU069288; ABS88353.1; -; Genomic_DNA. DR EMBL; EU069289; ABS88354.1; -; Genomic_DNA. DR EMBL; EU069290; ABS88355.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 172 172 SQ SEQUENCE 172 AA; 19288 MW; C8315FB00D5178CE CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESCEGRRQA LR // ID A7UGW7_DROAE Unreviewed; 172 AA. AC A7UGW7; DT 02-OCT-2007, integrated into UniProtKB/TrEMBL. DT 02-OCT-2007, sequence version 1. DT 03-OCT-2012, entry version 6. DE SubName: Full=Timeless; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=IR04.53 F1; RX PubMed=17660565; DOI=10.1534/genetics.107.073932; RA Evans A.L., Mena P.A., McAllister B.F.; RT "Positive selection near an inversion breakpoint on the neo-X RT chromosome of Drosophila americana."; RL Genetics 177:1303-1319(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU069275; ABS88340.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 172 172 SQ SEQUENCE 172 AA; 19318 MW; C1F14BB00D516CCE CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESCEGRRQA LR // ID A7UUK1_ANOGA Unreviewed; 1263 AA. AC A7UUK1; DT 23-OCT-2007, integrated into UniProtKB/TrEMBL. DT 23-OCT-2007, sequence version 1. DT 03-SEP-2014, entry version 36. DE SubName: Full=AGAP008288-PA; GN ORFNames=AGAP008288, AgaP_AGAP008288; OS Anopheles gambiae (African malaria mosquito). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Anophelinae; Anopheles. OX NCBI_TaxID=7165; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PEST; RX PubMed=12364791; DOI=10.1126/science.1076181; RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., RA Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P., RA Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., RA Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., RA Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., RA Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., RA Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., RA Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., RA Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., RA Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., RA Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., RA Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., RA Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., RA Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., RA Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., RA Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., RA Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., RA Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., RA Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., RA Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.; RT "The genome sequence of the malaria mosquito Anopheles gambiae."; RL Science 298:129-149(2002). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAAB01008964; EDO63569.1; -; Genomic_DNA. DR RefSeq; XP_001689006.1; XM_001688954.2. DR STRING; 7165.AGAP008288-PA; -. DR GeneID; 5668288; -. DR KEGG; aga:AgaP_AGAP008288; -. DR VectorBase; AGAP008288; Anopheles gambiae. DR eggNOG; NOG257888; -. DR HOGENOM; HOG000008522; -. DR KO; K12074; -. DR OMA; LHIPETH; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; A7UUK1; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1263 AA; 141575 MW; AEA6594E612444BC CRC64; MEWLLANPQI NSTFGSLGTF EDDAYHLSED CLVTLEEIIC KLAVEDATLR TFRRAIGFGQ NVKNDIVPLL VNAKDVKIID TTIRLLVNLT VPVECLLPVD LVSKSEIGRH TIFELNKLLI TSKEAFVDWK TTKAVIDHMK GILERDTKLS IQQCDSVNNC LLLLRNILHV PEMGTGAGGH GGSCYPTAGH NTSFQNQIIW NLFTQSIDKL LIYLMSCPQR AYWGVTMAQL VALMYKDQHI STLQKLLNLW FESTLSESSE DNESNTSPPK QCSGDSSPML TSDPTSDSSD NGECLRRAGT GLMSAICILG SGKMPSSMSK ECASEAPQVT RMVADFPTQI ILSRAIKSHQ MYHQTLKANA ASSDGCVLGA GRPAAVRVRV KATELQEVSR NFVCSCALCW VFNLLTFFCS PKSPKVAQAA PSVTRIRPAA ARRRACFANS RPPAAKSSDE GEQQAVEWVT ISENSDCGYG TQVEKESIST SSNEDDSPHQ KPVHQKPPSN QKQRFNAANK QRNPVSVQEK KELRRKKLVK RGKSNIINMK GLMHHVPTDD DISHILKEFT VDFLLKGYGY LVHELHTQLL SDLQVQIDTS HFFWLVTYFL KFATQLELDL EHINSVLSFD IISYLTYEGV MLCEQLEQLS RATETDIKPC LRRIHLVVTA IREFLQALDT YKKSTHLTKE DKEKLKLLQL QISCTEDLRC LFVLLLRCYN PNIQSRQYLQ DLIVTNHTLL LLLDGVRELT ADGNPGDMLG HIKQFATVEI MHQYGLLLED FRENGAFVND CIFTMMHHVG GDLGHINVLF QPSILKTYSQ IWETEYELCD DWSDLIEYVI HKFINTPQPA PLTLSTTLPD IGTQLLSGNL LVTWTQEEKD SLHWYYVQCR QSKCVVADIL KLFQENGNQQ KTRLSIIEQL LEQNIVTLVQ YDDLMKVENP DYERNVQTPA LSVASADSPK PEDGDSKSSS KAVDDIQVLR DRLQKENRGK LIAWLQKSLL DCCFVKLNLL SGNIYVTAGI GGSTGVVVME PVSYHCILKK KSIPVVPWNQ DQFAILSYQP FILLLHKLGF HLPADAKKMF VRIPEFWTAD ILYNIALKLG PLDKSILKFD LKYLNKVLSM EKQAKADPCP SNDARLENFG LSRFSPQITT NWLDVVMRNK AVQSKRNKLD LPGPSKVIDT ANATHPSATL KSGGKPAAPS KMLHDLSIIV ESNDDDDDEL PADEDDGLDS TEVPVLEEHD VVSACETASV ASDLTRMYVS DEDDKHDIVP PIL // ID A7UV10_ANOGA Unreviewed; 1154 AA. AC A7UV10; DT 23-OCT-2007, integrated into UniProtKB/TrEMBL. DT 23-OCT-2007, sequence version 1. DT 03-SEP-2014, entry version 35. DE SubName: Full=AGAP010787-PA; DE Flags: Fragment; GN ORFNames=AGAP010787, AgaP_AGAP010787; OS Anopheles gambiae (African malaria mosquito). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Anophelinae; Anopheles. OX NCBI_TaxID=7165; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PEST; RX PubMed=12364791; DOI=10.1126/science.1076181; RA Holt R.A., Subramanian G.M., Halpern A., Sutton G.G., Charlab R., RA Nusskern D.R., Wincker P., Clark A.G., Ribeiro J.M.C., Wides R., RA Salzberg S.L., Loftus B.J., Yandell M.D., Majoros W.H., Rusch D.B., RA Lai Z., Kraft C.L., Abril J.F., Anthouard V., Arensburger P., RA Atkinson P.W., Baden H., de Berardinis V., Baldwin D., Benes V., RA Biedler J., Blass C., Bolanos R., Boscus D., Barnstead M., Cai S., RA Center A., Chaturverdi K., Christophides G.K., Chrystal M.A.M., RA Clamp M., Cravchik A., Curwen V., Dana A., Delcher A., Dew I., RA Evans C.A., Flanigan M., Grundschober-Freimoser A., Friedli L., Gu Z., RA Guan P., Guigo R., Hillenmeyer M.E., Hladun S.L., Hogan J.R., RA Hong Y.S., Hoover J., Jaillon O., Ke Z., Kodira C.D., Kokoza E., RA Koutsos A., Letunic I., Levitsky A.A., Liang Y., Lin J.-J., Lobo N.F., RA Lopez J.R., Malek J.A., McIntosh T.C., Meister S., Miller J.R., RA Mobarry C., Mongin E., Murphy S.D., O'Brochta D.A., Pfannkoch C., RA Qi R., Regier M.A., Remington K., Shao H., Sharakhova M.V., RA Sitter C.D., Shetty J., Smith T.J., Strong R., Sun J., Thomasova D., RA Ton L.Q., Topalis P., Tu Z.J., Unger M.F., Walenz B., Wang A.H., RA Wang J., Wang M., Wang X., Woodford K.J., Wortman J.R., Wu M., Yao A., RA Zdobnov E.M., Zhang H., Zhao Q., Zhao S., Zhu S.C., Zhimulev I., RA Coluzzi M., della Torre A., Roth C.W., Louis C., Kalush F., RA Mural R.J., Myers E.W., Adams M.D., Smith H.O., Broder S., RA Gardner M.J., Fraser C.M., Birney E., Bork P., Brey P.T., Venter J.C., RA Weissenbach J., Kafatos F.C., Collins F.H., Hoffman S.L.; RT "The genome sequence of the malaria mosquito Anopheles gambiae."; RL Science 298:129-149(2002). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAAB01008979; EDO63465.1; -; Genomic_DNA. DR RefSeq; XP_001689129.1; XM_001689077.1. DR STRING; 7165.AGAP010787-PA; -. DR EnsemblMetazoa; AGAP010787-RA; AGAP010787-PA; AGAP010787. DR GeneID; 5668064; -. DR KEGG; aga:AgaP_AGAP010787; -. DR VectorBase; AGAP010787; Anopheles gambiae. DR eggNOG; NOG297449; -. DR HOGENOM; HOG000122270; -. DR KO; K03155; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; A7UV10; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1154 1154 SQ SEQUENCE 1154 AA; 133108 MW; 6A3ADCA2C8820BAC CRC64; MSAYFADIDA VCSSLGWMDG EVYKMDPEAV QGLKHLIWIL KQDRPAHECR RYIGGKRIVQ TDLIPMVISN FDKPDVVDVL LRLLVNLSFP TLLLYNGNYP KDAAEQRKFI RLMEICEEYK EAFSLKSVWS VLGDRLEKIL HTDWALRSEA DGLIIERILV LIRNVLQVPA NVEREKRFDN DASQHDCLLW ALHQAGILDI ILYILGSPHE NRFLIHTLEI LSLAYREQSA VHLADATLQR TNTEKKTDEL LLIKARQPTA AAAAATTPAA LGKPPAGRHS RFRGTYTFNN VKSISDSDAV CHQSLGKIMR MDFSSEKHRQ KVSFRNAKET ETFERKSIFS VRLFLREYCM EILRVYNNMV RQARRYLNQH GTSVSEFHDD SYLLWAIRFF LEFNRHSGFK IELVSESLNI DTFHWTVTRM DTYTENITTD KTRKAVWARR LHLTIQTYRE LLNNMHALEK IKDTAASELL SVLQNNIFYV VEYRETTLHL LTSFKEALHT KAYLRDVIEV AHLFFSMLQR FCKGTVRVQE RVKAKRKKAK KQPRKKTTEE EEENIENRWL QEAPTIASLL ENGELKQQEL PTPFDSASSV PVEEQKGDCL KSIHSLLRKK NYEQAIKMLY AARSVWTTSS CFGSETATPD EDLITLQDIF AANLSSATDA DDNDGEVQED SEEEDELEEE GKQCLEEFEI VKHEEKDFKF EEFSKRLVDH RVVYACTTVL TDWEKIKTTC LKAAVTLLYR ICVEHKMPSM LFQVSLLRIF QAVLNAIEDE HSRELRRLAI YTVRQLQQKV LTGAEDDGGL LFAELLFAKT SRIACALEIG YDEVKSTASQ KAWTEEQEQE LHRLFMENQE NPQTDQDVID WLLENLIDQT RTRRGVMKKL KEMGLTFKAP TKKSNANRQQ KANAWTADED GKLGVLYEEL RLDKNPLKSI AEAFDKKFTR PAIARRMVYL GLIADVAEIM PSKRRANKER RASGSDGSSQ DDERNSNSTD EEEEEEKEEE FNQSINKQLN EPLVKKNLKA LRGDDMKQAV RWIVECFEEV RSLYEDSDPS EDTEGGVPMI PIAPYQTAAL KKPEFKRLLR SLGVMDTGRQ FVYHRIPFQL TPEELKKRME ILTAFCEAPT AADEDEEAGD RSVVSPSAAS EDEMDKNNHY EKER // ID A8P182_COPC7 Unreviewed; 1126 AA. AC A8P182; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 2. DT 13-NOV-2013, entry version 16. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=CC1G_07534; OS Coprinopsis cinerea (strain Okayama-7 / 130 / ATCC MYA-4618 / FGSC OS 9003) (Inky cap fungus) (Hormographiella aspergillata). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Agaricales; Psathyrellaceae; OC Coprinopsis. OX NCBI_TaxID=240176; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Okayama-7 / 130 / ATCC MYA-4618 / FGSC 9003; RX PubMed=20547848; DOI=10.1073/pnas.1003391107; RA Stajich J.E., Wilke S.K., Ahren D., Au C.H., Birren B.W., RA Borodovsky M., Burns C., Canbaeck B., Casselton L.A., Cheng C.K., RA Deng J., Dietrich F.S., Fargo D.C., Farman M.L., Gathman A.C., RA Goldberg J., Guigo R., Hoegger P.J., Hooker J.B., Huggins A., RA James T.Y., Kamada T., Kilaru S., Kodira C., Kuees U., Kupfer D., RA Kwan H.S., Lomsadze A., Li W., Lilly W.W., Ma L.-J., Mackey A.J., RA Manning G., Martin F., Muraguchi H., Natvig D.O., Palmerini H., RA Ramesh M.A., Rehmeyer C.J., Roe B.A., Shenoy N., Stanke M., RA Ter-Hovhannisyan V., Tunlid A., Velagapudi R., Vision T.J., Zeng Q., RA Zolan M.E., Pukkila P.J.; RT "Insights into evolution of multicellular fungi from the assembled RT chromosomes of the mushroom Coprinopsis cinerea (Coprinus cinereus)."; RL Proc. Natl. Acad. Sci. U.S.A. 107:11889-11894(2010). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AACS02000006; EAU83799.2; -; Genomic_DNA. DR RefSeq; XP_001838044.2; XM_001837992.2. DR GeneID; 6014613; -. DR KEGG; cci:CC1G_07534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1126 AA; 127809 MW; 3005A77BB44412B4 CRC64; MDPKEIIEIF DDEEDDEPTQ APNGYPDIDR RELLTPIITR VVDALGGYEG NEYKLGDESY GCLKDLKRLW RKDDTDDDRT VARIFYETRV LPNDLIPILL TTAGQGLVED KRAIACADLM TAMTWPIDVA EELKELDDEI DEKADYTQLI ESHLTYKAAL LKTGVMKALF GIILPPLAKK RSERQERDGQ IINVVLHLIR NLAFIKDLPP DSTSSADNVE MSSLQSKLIR ILEETHILRL LLTIAANHDE DPLFNSWNTL VLEIFYLLFR GIKPVDLAAD QAKRSAVNLK QLLAVEERNR REVARKASSR HSRFGTTITV SLKKPPAADN ETVTRPIVLH RQQAIHGEAG SILDIRKKGK AKKGNTIDEL TREDNLSIEA RVTLKQLATD FLEGCFNPFL AGLLKDIRAE RAKVTEKDNL RLLYVTKWFL EFFLAMRAKA HGQGNPDQWS FGLIAEVVER VWIVWVLKRM RESMEEKPKL WTELQAGIEC LTQLFLLIDA MSSADIQDPT LSEAAELLLQ QLIYNGEVLD ISLNSLQFYK EGTQSLTYLD SSVHLAYSLL RMLERWTKKS GDGTYVRKKM AKRKKRRPRG RSPETEEAGM AAGEADDDEG DDEDVVHEVL FSFEAFEMKF ANADITNTLL TYLARYKEFS SPEKMKRVVS LMHRQAVKAK AEGLFFKAFF PKNRGNWKQY SSWEPEKKKA REGGVGGRNA AGKNASTEVE VKKGYSLTDQ IGIAIAALVD SDRRDLVVWT QDILRMAVNK RKRIIDETDD KSDNEDEDIV ENDAADAAKD KSKRYENPSE EARQKIQDEV IPYVTEDRAE AASKNAYLKL LFRLVKFMTR ERDEDDEEGE LEWYIPASLT PVHLERFRTI INQFLETPFD PSGKKLSELL RKKRRSRRRR TPSPSPSGSD IDEDGERRKK KRQRKEKEKQ VYKSAQFIED SDEEYGDMEA FLAREKALRE KMGLIAERAE AEAAANGGGS TGVQGQRPVG MRATGTKKRR KRKTKDSDTE RDANSRGDVE MDKEPSDKDD EVEEVSQPKP KPRPRPRPRK SQPTPSASGD SPRASSPSIP PRDASPVPST ARQGASPSPS LSKKSQDGDD ENDEEDGPVV KRRAKRLFLS DSEDDE // ID A8PC46_BRUMA Unreviewed; 1138 AA. AC A8PC46; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 09-JUL-2014, sequence version 2. DT 03-SEP-2014, entry version 15. DE SubName: Full=Protein Bm7139, isoform a; GN Name=Bm7139; ORFNames=BM_Bm7139a; OS Brugia malayi (Filarial nematode worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Spirurida; OC Filarioidea; Onchocercidae; Brugia. OX NCBI_TaxID=6279; RN [1] RP NUCLEOTIDE SEQUENCE. RA Ghedin E.; RL Submitted (NOV-2012) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HF575285; CDP95341.1; -; Genomic_DNA. DR KEGG; bmy:Bm1_21675; -. DR CTD; 6099243; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1138 AA; 132856 MW; 88AC892CA4019C9D CRC64; MERIIQATIN ALGFLEDDVY FPEPDCFESI RDLIRFLRND TITAVARRVC GERNIVRYDL IPIMKSPNTP DKLFDIALRL TINLCQPVSL MFAGRHPEDK EAWLIYQEIE QNLRNSKEAF GDIQLFKTFE RKAATYFAQD WLERNEEMKL LVERIFALSR YVLAIGDTDL DKERVPQDMN SHDQLVLAIL ESGFGKLLVE ISENSAERDF HLWILEIFAM LLKQHEAKDV VAAGSIRTAE ERKRQENEMR KVVEQETEKQ LNKRRCISSR HTAFAGSYIL KGLKAINKDN DMIVNKVIKN CNDIGHLNKR KIQHRAPKSR RPFDIETNKH ISALNVRIVL RSFCIEMLQK SYCRLICGCK DGAFSGKRTL GQDKADIHYF ILMQFSLEFC RLADLSPEYI KASLSIEAFH HVQTQLDDYL EKVRIERKEG RLHGLRAQYA LAAYKELLLM LISVLKSGNE EWKREVGSAC LHILRVEEYR DLSSCVIRKF MPGVFSKTFL RDVVLANHAY ISLIEKFSKK GMLSTVVKRQ KMRRRKSKKK EKLDDSIVNE SKEPDWNLWD DISEELSDVI FGYIEPTVDI SVIDVLLNVE DRIHQQFAML MVQQALRQRR VADAVGIYRS ARDLWPVNDV FGTNDITPDD EFLELYAIYF VDLKEVEANW KKYRLEAYGP ELDDDTRNDI LFSDEFDEFD DEYEERSGES GAETNIVEKE IDFHFDNYVA KFARVDVLKW YIFLLADFES NTFEVNKAVL KLLHRVAFDL KMASRLYQLS LFVIFKRLSQ RFKHQSISEI KKTQYFEIYQ FGYHILRRFY ADYQKIGSKL IPELLFWKGP KECYEIDNGY GTFEIKSDGS KGKEILWPEE LDNELRALYD EYLLFEEKPE GVDIVEYIEQ GLSRPRTRRQ IIRQMKMLGL NTFGARGTRR YMERGFKSSV FTPEIVNQMH NLIDEFNSKT PPSGSDSKGD LVNFIRSNLT EKYTRAKIIK QLQYENIHYE QPPRKRYSKI PQKLIEQRES GEEEIDQLLE DSNMLGFGHS RQRNDEYGKR ELNKTNKSIT CLSPEDDLKS TDGIISSNIF EHASSRSNGN TEVDELLTTC ETNSVITNNS DDEIILGKRE RPIAVSDEDD NTTSKKTRTK RIIESDSE // ID A8Q4M7_MALGO Unreviewed; 1050 AA. AC A8Q4M7; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 15-JAN-2008, sequence version 1. DT 22-JAN-2014, entry version 20. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=MGL_2578; OS Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) OS (Dandruff-associated fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; OC Exobasidiomycetes; Malasseziales; Malasseziaceae; Malassezia. OX NCBI_TaxID=425265; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4612 / CBS 7966; RX PubMed=18000048; DOI=10.1073/pnas.0706756104; RA Xu J., Saunders C.W., Hu P., Grant R.A., Boekhout T., Kuramae E.E., RA Kronstad J.W., DeAngelis Y.M., Reeder N.L., Johnstone K.R., Leland M., RA Fieno A.M., Begley W.M., Sun Y., Lacey M.P., Chaudhary T., Keough T., RA Chu L., Sears R., Yuan B., Dawson T.L. Jr.; RT "Dandruff-associated Malassezia genomes reveal convergent and RT divergent virulence traits shared with plant and human fungal RT pathogens."; RL Proc. Natl. Acad. Sci. U.S.A. 104:18730-18735(2007). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAYY01000009; EDP42982.1; -; Genomic_DNA. DR RefSeq; XP_001730196.1; XM_001730144.1. DR GeneID; 5854503; -. DR KEGG; mgl:MGL_2578; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1050 AA; 116534 MW; B2564D0E9FAC4D78 CRC64; MSRVASEVDA WDDDQFAEDE LAESVGTSSG TEAGVDTDAD ADAASADEGH DNESVDDVDE RVALLRAPIL SICSALGGYE HMMRQGRTEI VYRIGDDCLE CLRDLRRLWR QDDTDASRAI ARVLADLGTL HNDLIPILLH CAGADASEKE QKIALACTDL MTALTWPIDW SAELHDIATR EEDEHVLSKL LELQGAQVQY KASILRVRAK EPRLSDRTVL SCVLRHVLVP SLKPRTERTD RDIGVVSMCL HFFRNLLTIR DPPLHTTKSS TNIANTALHS VLVQQMESAH ILATLRMLAS QADSKDYDLW TPVVADCVYQ MYAGSIPSQL SNAGGANAQA SNYAGARGPA HLLAHSLASE ARTKRASLRG ASARHSRFGT SIQFRAHDGT LRMAHSPAAL TDSVAHLEQR VMDRTKRRVS RQRPATERGA PPRRVLWTPG AAAVLCRWAD QFVQDGLLDV LVRAYLRDIH AERERVGDLD MARCKAMYIA SFFIDYALAR HMRLELVSAW LEPWSFRLVR ARTAVALENR QWLEFTVSLR LWTVLLKLVD ALSRGSPTEQ EAADSLQHTL YYDGDLLDTA LHAMHAYSAQ SFACLEAVVD FAYMMPRLLE RHAAKSAYMF VKQRRRRQPG QHDTDDQTDV PPDADTNVRS ERVFRFESFE RAMASASLVH ACTQYLARYR DSEHAHVMLP KLASVVYRII VRVSRVALFF SAKVRRVWAH AMRDSFALRQ AHERAASDLT RLYHIIHKSF TRLSEASRAA YNADRRPPKP ALEMFVRSDL SHSEQIGVAV GLLAEAHKLT CVSWVRAALE RASAERMAMG DMDPMHPPPA LQAQFPVHEL PDGGGHDAVH CAPLRLLCRL VGLKSEARGS DATVWYVPTD CVPGALTRCA RVIDQYLAEP FVLEGHALSD LVRMKRPTQG SRTSDHARKK ARQESRASPL QADASESDNG SDGHERFVFS TNAEHSERDV PGLSDTYTAS QTASSSPLAD HAPEASTDRG VTDATRATGH LAPTPALVLQ EGLYHKEAPI SARPIRTGSP GLFFSDSDDN // ID A8W369_9MUSC Unreviewed; 1356 AA. AC A8W369; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 15-JAN-2008, sequence version 1. DT 03-OCT-2012, entry version 6. DE SubName: Full=Timeless; OS Chymomyza costata. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Chymomyza. OX NCBI_TaxID=76946; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=18375862; DOI=10.1177/0748730407313364; RA Stehlik J., Zavodska R., Shimada K., Sauman I., Kostal V.; RT "Photoperiodic induction of diapause requires regulated transcription RT of timeless in the larval brain of Chymomyza costata."; RL J. Biol. Rhythms 23:129-139(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU189083; ABW71827.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; SQ SEQUENCE 1356 AA; 152948 MW; 3E1735F65173FCA4 CRC64; MDWLLATPQL HSAFSSLGAL VGDTYVVSPD ALAILEEINY KLIYEDQTLR TFRRAIAFGQ NVRSDLIPVL ENTKDDAVLE SVIRLLVNLT VPVECLFSVD VMYRTEMGRH TIFELNKLLY TSKEAFTDPK STKSVVEYMK HILDSETKLS PQKCDQINNC LLLLRNILHI PETNANFIMP MLQSSSRLGT SMQNTILWNL FIQSIDKMLL YLMTCPQRAL WGVTMVQLIA LIYKDQHIST LQKLLNLWFE ASLSESSEDN ESNTTPPKQG SGDYSPMLTS DPTSDCSEKD GDERRQTLRE GTDATLQEVS RKGQEYQDAM FGVPAKKLEC AEIASDMTSE APSSPQQQWK VTEPPKLEKE MDMAANTEQQ ASMLMQLTQP ADNAKTTTNT TCIANQERFK QPPPLPVRPL TCTQAEKLGE MAAETYPKHV SGVKLGQKSP HSGQLHLTKG KCFPQKRECA SSQSELSDCG YGTQAENQES ISTSSNDDDA PQGKPQHQKP PCNTKPRNKQ RNIVTPLDKK EQRRKKLVKR GKSNLINMKG LWQHTPTDDD ISNLVKEFTV DFLLKGYNYL VKVLHLHITS NAKVSIDTSH FFWLVTYFLK FAAQLELDME HIDTILNFDV LTYLTSEGVS LCEQLELNAR QEGSDLKPYL RRMHLVVTAI REFLQAIETY SKVTHLSEDD RTQLLKLQIQ ISAATDLRSL FVLLLRRFNP SIHSKQYLQD LVVTNHKLML VLDRAAKLEG GQSVNLTEHL LQFATPEVMH YYGILLEDFN YNGEFLNDCI FTMMHHIGGD LKQVGVLFQP IILKTFSRLW ETDNGLCDDW TDLIAYVIRK FMNTPPKSPL ILPNTSLTEM TKEHNLQNNL FTWTQEDMET LYWYYVQSKK SNDVVGKIVK LFSNNGNKLK SRISIIQQLL AQDMINLLEY DDLMKFEEAE YQRSLLNTPT SGTNASGEES GKPSNDTQML LDLIIKDNKQ QHLIWLQQLL LECCYIKLKL RSGNSCSTDA IMEPVAYHCI LMQKSIPIVQ WNNDQSAIML YQPFVLLLHK LGIQLPADAG TIFARIPDYW TPETMYVVAK KLGTLDKLTL KFDPIELMVA SSTTSRHCMR SRNSLSSVSS LDVDMPESEE LPLIPEVDAA IEKAHEIFVA PKAKNCNSII RCTPDVTPAV PNWLQLVMRS KCNQQSAPSR PATDISDCTG ADDESMHSSS QQAPTQQLSA TSNSSNVNHT TTLGCQPSII GAHNDNSSSS GCGGTDSSQS MAAVVSNTIT TGNNTPRKTA EAISRKTTHM YEDAAMKSFQ RLQATNSHFS CANNLEQQYS ALVASVYENE MANCDNISMA SDLEHMYVSD EEDTHEIHEQ RVPYYH // ID A8W370_9MUSC Unreviewed; 1356 AA. AC A8W370; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 15-JAN-2008, sequence version 1. DT 03-OCT-2012, entry version 6. DE SubName: Full=Timeless; OS Chymomyza costata. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Chymomyza. OX NCBI_TaxID=76946; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=NPD; RX PubMed=18375862; DOI=10.1177/0748730407313364; RA Stehlik J., Zavodska R., Shimada K., Sauman I., Kostal V.; RT "Photoperiodic induction of diapause requires regulated transcription RT of timeless in the larval brain of Chymomyza costata."; RL J. Biol. Rhythms 23:129-139(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU189084; ABW71828.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; SQ SEQUENCE 1356 AA; 153019 MW; C6EDA50E2996D1A1 CRC64; MDWLLATPQL HSAFSSLGAL VGDTYVVSPD ALAILEEINY KLIYEDQTLR TFRRAIAFGQ NVRSDLIPVL ENTKDDAVLE SVIRLLVNLT VPVECLFSVD VMYRTEMGRH TIFELNKLLY NSKEAFTDPK STKSVVEYMK HILDSETKLS PQKCDQINNC LLLLRNILHI PETNANFIKP MLQSSSRHGT SMQNTILWNL FIQSIDKMLL YLMTCPQRAL WGVTMVQLIA LIYKDQHIST LQKLLNLWFE ASLSESSEDN ESNTTPPKQG SGDYSPMLTS DPTSDCSEKD GDERRQTLRE GTDATLQEVS RKGQEYQDAM FGVPAKKLEC AETASEVTSE APSSPQQHWK VTEPPEPEKE MAMAAITEQQ ASMIMQLTQP ADNAKTTTNT TCTANQERFK QPPPLPVRPL TCTQAEKLGE MADETYPKHV SAVKRGQKSP HSGQLHLTKG KCFPQKRECA SSQSELSDCG YGTQVENQES ISTSSNDDDA PQGKPQHQKP PCNTKPRSKQ RNIVTPLDKK EQRRKKLVKR SKSNLINMKG LCQHTPTDDD ISNLLKEFTV DFLLKGYNYL VKVLHLHITS NAKISIDTSH FFWLVTYFLK FAAQLELDME HIDTILNFDV LTYLTSEGVS LCEQLELNAR QEGSDLKPYL RRMHLVVTAI REFLQAIETY SKVTHLSEDD RTQLLKLQIQ ISAATDLRSL FVLLLRRFNP SIHSKQYLQD LVVTNHKLML VLDRAAKLEG GQSVNLTEHL LQFATPEVMH YYGILLEDFN YNGEFLNDCI FTMMHHIGGD LKQIGVLFQP IILKTFSRLW ETDNGLCDDW TDLIAYVIRK FMSTPPKSPL ILPTSSLTEM TKEHNLQNNL FTWTQEDMDT LYWYYVQSKK SNDVVGKIVK LFSNNGNKLK SRISIIQQLL AQDMINLLEY DDLMKFEEAE YQRSLLNTPT SGTNASGIES GKPSNDTQML LDLIIKDNKQ QHLIWLQQLL LECCYIKLKL RSGNSCSTDA IMEPVAYHCI LMQKSIPIVQ WNNDQSAIML YQPFVLLLHK LGIQLPADAG TIFARIPDYW TPETMYGVAK KLGTLDKLTL KFDPIELEVA SSTTSRHCMR SRNSLSSVSS LDVDMPESEE LPLIPEVDAA IEKAHEIFVA PKAKNCNSII RYTPDVTPAV PNWLQLVMRS KCNQQSAPSR PATDISDCTG ADDESMHSSS QQAPTQQLLA TSNSSNVNHA TTLGCQPSII GAHNDNSSSS GCGGTDSSQS MAAVVSNTRT TGNNTPRKTA EAISRKTTHM YEDAAMKSFQ RLQATNSHFS RANNLEQQYS ALVASIYENE MANCDNISMA SDLEHMYVSD EEDTHENHEQ RVPYYH // ID A8WVE9_CAEBR Unreviewed; 1404 AA. AC A8WVE9; DT 15-JAN-2008, integrated into UniProtKB/TrEMBL. DT 16-DEC-2008, sequence version 2. DT 11-JUN-2014, entry version 33. DE SubName: Full=Protein CBR-TIM-1; GN Name=tim-1; Synonyms=Cbr-tim-1, cbr-tim-1; GN ORFNames=CBG03593, CBG_03593; OS Caenorhabditis briggsae. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6238; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AF16; RX PubMed=14624247; DOI=10.1371/journal.pbio.0000045; RA Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N., RA Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., RA D'Eustachio P., Fitch D.H.A., Fulton L.A., Fulton R.E., RA Griffiths-Jones S., Harris T.W., Hillier L.W., Kamath R., RA Kuwabara P.E., Mardis E.R., Marra M.A., Miner T.L., Minx P., RA Mullikin J.C., Plumb R.W., Rogers J., Schein J.E., Sohrmann M., RA Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K., Durbin R.M., RA Waterston R.H.; RT "The genome sequence of Caenorhabditis briggsae: a platform for RT comparative genomics."; RL PLoS Biol. 1:166-192(2003). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=AF16; RG WormBase Consortium; RL Submitted (OCT-2010) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE601339; CAP24460.2; -; Genomic_DNA. DR EnsemblMetazoa; CBG03593; CBG03593; CBG03593. DR WormBase; CBG03593; CBP33035; WBGene00026429; Cbr-tim-1. DR HOGENOM; HOG000017205; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1404 AA; 161529 MW; 9B838E571A457356 CRC64; MNVLIQGAVQ ALGYCEDGKY FREPDCYETI RDLIRYLRED GEDYGARIEC GRHNLIEQDL VPMVKCEDLS DDEFDIAIRL MVNLCQPAIS TMRGKPPTDR DQWKMYWELE ENLRRAKNAF TDAYFFVAIK KRIDAYFIDT DFDDRDERLR LVVERIVSLI KYIFSINPDT SEGRRTRIED SNHDRVILAF LESGIDKTLM HIANQPREKE FHITILDIFA LILKEQSPEC LSKSEDESEI SAAEKKKTEE EFRKIIENHV VRETQKRKSF SRFGGSYTIK GLKGISSNSN QVVFKPIQNV EKHNFLDERK AKKRVARNRR PFEIDTNTHF ASSEVQKMLK DMVIRLIETC FNRLMKSAKS TVFVQGHVIH KTSQINYFFM MDTLLERISE CTGMEAFHEN NVQLTEYVEN AMTLKGVEAK SFGLKAQYAL GAYNELVLLH RYIVEHGKDE SEKKRARRAL EHITNVEEYR ELPISIIKKF SSTVLSNNFL RELVLTTHHY IKLVERFVKV GALKKVTKKV KIRKNQKKIV EENDERSIFD KMSSEALDAL WEESKDTILQ ILNEEIPEIQ GMKPIDSQLE GINEETQKKF AKLAIQRSLR ARGFPAAVGL YHASRKIWDD GSFGTDSAKS EGELENLHKI LKLDLKKVAN ALRRAEAKIV PENERVDKMT KEALEAFWED PNTLETLQGI LNKEIAEAED ANPLNWQLDV APQAQQQFAM LSIQRALRAN YLPLAIGLYH SSRRLWPDED FFGKPEITVK EEISELEGIL KADLGEVAKE MKAAEEEANK KFDGSLEEEG DVMNSEDEDD EENRYKTEEI DFQFDLYVSK FANVDVLKWY VFLLNDFSKN SVELNQALVK MLHRIAFDIK LPVKLYQVSL FQIFQKVNEH FSHLSKELRK TSPLFELYQF GFHLLKKFFA KFTEMGADLA VEALFWKGPK ECYEIDNGYG SYTKAREADI KVWTEELETE LRNLYDEYKS VEGEGGVDVL DFIQHSLSRS RQRKQIAKKL IEFGLDLLGA KWKNTEGSRM DAVLPVGDIQ KWHDEWKEAG SVGDVVEVLK EKLTESLGSE ISRKKIIKQL AHMDILYEKP KKEKPLPEWD SGLIEELTGL KEQYEEIDDA ENLLPEHQYK VSFPVGVDMV AYVMKRLSVK KPTRQVERYL ASMGVKIVER VAGKSKKKKE KYEQFINDSS DDEQPPVASD AASDGEDDAE NDDGLRRPEP SSSKKRVILE SDDEEEEVPR VPTPSEKPRE KSAEQSAPSP PKTNTLMSRI MNKKRKITQL ASDSDSSDSE DESQERIEKK KASEDDSDDE AAIYKVNYLK FGTEPSFGSV ACRRSGRQLS SGSAALTCVG KYRSYVNALL TTGSVAAGGI SDDRDTSEEP DEDPFTKKMK YKRRIVMSDN EDED // ID A9SXS1_PHYPA Unreviewed; 1480 AA. AC A9SXS1; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 19-MAR-2014, entry version 20. DE SubName: Full=Predicted protein; GN ORFNames=PHYPADRAFT_231531; OS Physcomitrella patens subsp. patens (Moss). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Bryophyta; OC Bryophytina; Bryopsida; Funariidae; Funariales; Funariaceae; OC Physcomitrella. OX NCBI_TaxID=3218; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Gransden 2004; RX PubMed=18079367; DOI=10.1126/science.1150646; RA Rensing S.A., Lang D., Zimmer A.D., Terry A., Salamov A., Shapiro H., RA Nishiyama T., Perroud P.-F., Lindquist E.A., Kamisugi Y., RA Tanahashi T., Sakakibara K., Fujita T., Oishi K., Shin-I T., RA Kuroki Y., Toyoda A., Suzuki Y., Hashimoto S.-I., Yamaguchi K., RA Sugano A., Kohara Y., Fujiyama A., Anterola A., Aoki S., Ashton N., RA Barbazuk W.B., Barker E., Bennetzen J.L., Blankenship R., Cho S.H., RA Dutcher S.K., Estelle M., Fawcett J.A., Gundlach H., Hanada K., RA Heyl A., Hicks K.A., Hughes J., Lohr M., Mayer K., Melkozernov A., RA Murata T., Nelson D.R., Pils B., Prigge M., Reiss B., Renner T., RA Rombauts S., Rushton P.J., Sanderfoot A., Schween G., Shiu S.-H., RA Stueber K., Theodoulou F.L., Tu H., Van de Peer Y., Verrier P.J., RA Waters E., Wood A., Yang L., Cove D., Cuming A.C., Hasebe M., RA Lucas S., Mishler B.D., Reski R., Grigoriev I.V., Quatrano R.S., RA Boore J.L.; RT "The Physcomitrella genome reveals evolutionary insights into the RT conquest of land by plants."; RL Science 319:64-69(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS545023; EDQ63994.1; -; Genomic_DNA. DR RefSeq; XP_001771145.1; XM_001771093.1. DR STRING; 3218.JGI231531; -. DR GeneID; 5934389; -. DR KEGG; ppp:PHYPADRAFT_231531; -. DR KO; K03155; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SUPFAM; SSF48371; SSF48371; 3. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1480 AA; 166678 MW; 78A715281A462D30 CRC64; MDDFSHEVKG FPEISRWHCR YECGILVNTY ARFVSGFLRG SQEVEMDVDH VTAVCTGLGS LRESGSGRAV YVKHADCLAN LRHLQRFLRR DDPVQRDIFM QLGKWNSIRQ DILPIINHYR HDFDLVLNAV KVMVFLTMPI DPSSTDIPQQ LEYLRQFKSA VLEDDSIGVI VSHLQDPLEH MESGTLTDMD GKMFQLVLTL IRNLLAVDDP SSSLVRASVA SPQALYVKDA LIERLFNENV MDLLLALIQH VGGEQPFLRH DNLLILEIFN YLFSGQMPDV IASSYDEAHA KSKSQPSGAA LEALMAKERE ERRNRGFVGP RHSNFCGMFV RVGKDGSKTM VTRNPYQSPL DNLFQKPEIK RGQVKKVASD LPVHVPSNST VCSMLKVFAD QLLEGNYNLL MQTIIDDIRG ERNNVQSQDI VMFFAVAKFF TAYQRCHLMK KPNEGVQSAG ERGDPAGDSG PTFQGRCGRI ASTMDEDMFI LVTMKWQCFV ENAKLSNDWF PATSSGELLK EMIHMLDYIL KAADRNSSEG QQEVRVARIL FQLAGLVETT HIVLRLLDSI TKEDGALRVK KKARGTKKSS KLSRKKGVQP SGSTRKEPDH KSGSIHEVEE SNTSNEPLVA PEDPNSNTLL SNILHAQHAD TNFGPVEDIE VAGVEGHHGV TDEHDFDEVE DKEVHDVEES EMDSEEEEEE EVQTKEETLD VMKCVRMFAD NSILHNYCWL LKNYLLNTPA INYYIVRMLQ RISQDCMMEP MLYQLSILQT CYEILSNHSL RNSEQHQYVI AFLTSLVRHL FEKLKSSPML FVDILFWKSK QDCHCITANY MIHDLKKFSS SGKTLSKWAQ LEDRRSLLDG LGDDDDDDSG KETHAQNRRA LLNSLGDGDD DLGNDGNLPS VETLFSNKEK GKVKRQKAVK KKGLFTDFQE DLIKDLFKTF EKNRSCNKLI AEGLEKAGAV QDSGEPFTPS QIGRGLKRLG LARVVGKITQ NKFLRNIRND SENEDGSDSD NQENTHHTDA QRDHDPDSRS DEEISEEEDI AGPGGMKGLL ESLDEESDDE DSNQDDILKN DVLSAEKNDL KGSKKKRKSG ISEISGGNEV PKRRRKSGLF SKEQDHKLQS LFEKYKGMTR FKHLISNDLE GDFTTAQIER RLQQLGCVEP RKRKSKLAQM SDDEDKSEKE DDVEPNPDDS KEGQHADINV SSAFKASWGL SARKHTQINK PTADVHHETQ QGDSSDDNIP LAQHLSMRNS LRKKKAHPNN EGPREELEVG MGVGGENTGA KDAADEIQVS GVVVSCELPR PSEVGMLEDQ PKTTNSASKD CDSDDQLLEK SETGKVSKVF QRKRRQSGRH PIEGVMDKFE VSDGDRDDAI INAKKTHERK RRPSLEPKRS TWGDSDTDVS DIEDTQDLAA ALQEVRIYDN HLASTSKKRR LQRKQTSSND EVDVGGEELV TISSGVESYF QDDTTLEEHL LTRKGARKAL IDAMTSDEDE // ID A9V8H3_MONBE Unreviewed; 1492 AA. AC A9V8H3; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 14-MAY-2014, entry version 20. DE SubName: Full=Predicted protein; GN ORFNames=28544; OS Monosiga brevicollis (Choanoflagellate). OC Eukaryota; Choanoflagellida; Codonosigidae; Monosiga. OX NCBI_TaxID=81824; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MX1 / ATCC 50154; RX PubMed=18273011; DOI=10.1038/nature06617; RG JGI Sequencing; RA King N., Westbrook M.J., Young S.L., Kuo A., Abedin M., Chapman J., RA Fairclough S., Hellsten U., Isogai Y., Letunic I., Marr M., Pincus D., RA Putnam N., Rokas A., Wright K.J., Zuzow R., Dirks W., Good M., RA Goodstein D., Lemons D., Li W., Lyons J.B., Morris A., Nichols S., RA Richter D.J., Salamov A., Sequencing J.G., Bork P., Lim W.A., RA Manning G., Miller W.T., McGinnis W., Shapiro H., Tjian R., RA Grigoriev I.V., Rokhsar D.; RT "The genome of the choanoflagellate Monosiga brevicollis and the RT origin of metazoans."; RL Nature 451:783-788(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH991568; EDQ86145.1; -; Genomic_DNA. DR RefSeq; XP_001749070.1; XM_001749018.1. DR STRING; 81824.JGI28544; -. DR GeneID; 5894265; -. DR KEGG; mbr:MONBRDRAFT_28544; -. DR eggNOG; NOG328380; -. DR KO; K03155; -. DR OMA; YNARSES; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1492 AA; 166530 MW; 619979D0BE8DBFAA CRC64; MAAGATLEWA DGLLQLCSAL GLRGIDHEGG EDDQIYRIGA ESLEVLKDLL RNLRIDVRNE MRPVLRQLGQ FEILQKDLVP MLIQYCDDPK QSKLILTLLK YCFCSGLPPP PPYPLAPFPA QPPRLPPHLD TAFISCSRVM TAMTLPAFLV FQYEGQGQVN EKLEATAHYR QVELYLTRYK AACISYYRDH FDPEVTETSD QAISFTPRAL KALMTILYEP VTAELRSEQD ENLIELILTL LRNILHAPNP QMDNVHAESL HDKAVRAFNE AGVTDLVLGM CNNMGEFEPF KMMLLEIVSL LFREQSPQAL FEVIKESRHQ KVASRRDDKI RKLHEEEQAK RQATIKHIRT ARHSRFAGHY AVRGLGEQKG REVLTNVLAL QTPTNINNSG KAQRTKRALL ERAPDDRRSP LEVRMILYRQ ACAFIVDAYN VLMPAVAAEL ERYAESVGMQ AEVLDYDRSN YLKLMQFCMQ LHRLQLEEDG CHADLAETSD AQDPPGYVMD PIATTLSLNT LDNVQSWLQE YFDKMLERAL DAKLWSHRLH TAIRAFHELM QYASRLASSP VEEQRDYATN LISNAFYREE FLDVFPKLLI RYNARSESDV LLRDIVRTVH VVLKLLNSNT TKLYVKKKRQ TRRKKKTQPK AKGQPEGASS SNAEVAKPKA SKSAGKTNMD ADDLGGVRDT ALDELFSDEE GDGDKGADDT ANPTVTGEGG LNDEELEHYL QKQEDIQVQE AEFQFNNYLE KFKDFRVVKA YVEVLARYRY NGREMNHFAV KMLDRIVNPE KLNARQLLYQ LSVLRVFLGI LEDDVIRKQP EFAELRGFIK SGVIKDLIED LGKNPLLFVE LMFTKTTGDL EEIQHGYAEA LRRRNHKVVS WSPEEEAKIQ LLYKEHQESG YALDEILAAF PDRSERSVKL KMKKMGLVIS DSRVWTPEED AILKAEFAKI EGASDPIVAL LESGQMPSNK STRRQLGMRL RKLGLYEPPH YEKIDAELAS QLDAAATELR SMGMTGQLAL STLIERMETR ATALEADKAS DEQLAIFHPD DDDEEDIAEL RGLMGLLKFE GVDAEAITAW RMPADTSAQH LRDLIDALSP PGARTKESVV LQAERDADEF VHSSSEEDAP AEDNDDDEEE EAAFTDDDDD TTAASGQRPS KRVSGKKVKQ RRRRSRGSGA KGPHSTDKGS DNAASDDFDS DSEDNDNSED EELQEKKRRE ALAKLVQRRN ARKTTAELHR EAMLASKETT EAMAAVATST PSSARTGRVL ARKGDDSDDD DFSAMHVSTP LRTHGGPNVP QTPSSGSRVR RLQRLLAMSD DEDGEEAQGA VSTQGRQEDT TSLPKRMAAI SDDEDEPGTM DSKGEASSGA PPAKRPSPSR PVASRVLSDS EDEHSDVSSR AVGPGKRKAS SASRGLDSDL EVDTGAAPEP KRTDRQESAL APSPSALSSV EEEGASVAAD AVNVALLASL KPAPKHGDAE SKRVSTFTKH ALLSDDSSEG ED // ID A9XCF3_TRICA Unreviewed; 1107 AA. AC A9XCF3; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 19-MAR-2014, entry version 18. DE SubName: Full=TIMELESS isoform A; OS Tribolium castaneum (Red flour beetle). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; OC Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium. OX NCBI_TaxID=7070; RN [1] RP NUCLEOTIDE SEQUENCE. RA Zhu H., Reppert S.M.; RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF174306; ABO86540.1; -; mRNA. DR RefSeq; NP_001106934.1; NM_001113463.1. DR UniGene; Tca.18149; -. DR STRING; 7070.A9XCF3; -. DR GeneID; 657878; -. DR KEGG; tca:657878; -. DR CTD; 107698; -. DR eggNOG; NOG257888; -. DR InParanoid; A9XCF3; -. DR KO; K12074; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1107 AA; 127172 MW; 6049DE6C4C933B08 CRC64; MAHIHNMFAS ICVRNGDTLT ISDDCYEILQ EILRELLTED STLRTYRRAI GFGQNIKKDL LPLLTYLKDD AKESTRIIDT IIKILVNLTI PIEYLLPLEA MSQTDVGRHT IFELTKLLTS SKEAFTDSRS TKLIMDHVKF IVESDLEMNL EYCNSINNCL LLLRNILHVP EVKSVQNNAL THSSMQNQII WNLFTQSIDK VIIYLISCPQ KMYWGVTMVQ LIALLYKDQH VGTLQKLLNL WLEASLSESS EDNESNTSPP EQGSDDSSPI ITSDPTSDSS DGGGGKRNKT LNSTNLERNK KTLMMRGKST ETETSTSSGV STAHTSIDSA DSPKNDKAPL KNKRECPSSQ SEDFGYVTQV ENQESISTSS NEEDQPQLKP VHQKPHTFQK SRYNTGKSRA ATALDKKELR RKKLVKRSKT NTINMKGLLH HLPTDEDIAN ILKEFTVDFL LKGYGILVQD LHSQFLTNIH LQIDTSHFFW LVTYFLKFAT QLELDLEHVS PVLSHEILSY LVFQGVWIYE ELEMSGKIPD FDLKPCLRRL HLVVTAIREF LQAVETYQKM IHLSEDDRLA LLKLQNQITE MEDLRSLFLL LLRQYNPNIQ SRQYLQDLIL TNHNYLLFLD SATKERRSFN MMEHLKQFAT VEIMRQYGLL LESFKENGEF VNNCIFTMMH HIGGDLEHVA TLFQPSILKT FSLIWETDYE ICDDWSDLIE YIIHKFINSP RSNSDLNSSE TCHKLVVDEA EWTEEEKDNL LGYYNQSQFS NDTIANITKK YEKCGVRQKT QLSIIRQLLE QNIINESQYN DFIKVKQQPD RLKETKNIIP NQMDFEETPT DEGIRILREY LCKDNKTKFV LWLQKVLINT CYVKLALANP GEFNNDKALG QPVIYYFALL NLPIPVVPWT VDQTAILKYQ SFVLLLHKLG FYLPIDTGKI FVTIPNFWNA EHVFSMAQQL GPIDPAKLNF DVAIFKGRNR RELFKREITD ITNSIQTGKF SMNDSKQTPT MVRYTPLPNS TEWFQNDNFQ SRVLPIADFE VPINSAHPLS ITIPGLEELT CDLPPPELSI VDNHVINANM ECSPIHSACE TASIASDLTR MCVSDEEEKT ILVIEQK // ID A9XCF4_TRICA Unreviewed; 1079 AA. AC A9XCF4; DT 05-FEB-2008, integrated into UniProtKB/TrEMBL. DT 05-FEB-2008, sequence version 1. DT 01-MAY-2013, entry version 16. DE SubName: Full=TIMELESS isoform B; OS Tribolium castaneum (Red flour beetle). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; OC Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium. OX NCBI_TaxID=7070; RN [1] RP NUCLEOTIDE SEQUENCE. RA Zhu H., Reppert S.M.; RL Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF174307; ABO86541.1; -; mRNA. DR RefSeq; NP_001106936.1; NM_001113465.1. DR UniGene; Tca.18149; -. DR STRING; 7070.A9XCF4; -. DR GeneID; 657878; -. DR KEGG; tca:657878; -. DR CTD; 107698; -. DR eggNOG; NOG257888; -. DR KO; K12074; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1079 AA; 123959 MW; 2AC8EE2F199005EB CRC64; MAHIHNMFAS ICVRNGDTLT ISDDCYEILQ EILRELLTED STLRTYRRAI GFGQNIKKDL LPLLTYLKDD AKESTRIIDT IIKILVNLTI PIEYLLPLEA MSQTDVGRHT IFELTKLLTS SKEAFTDSRS TKLIMDHVKF IVESDLEMNL EYCNSINNCL LLLRNILHVP EVKSVQNNAL THSSMQNQII WNLFTQSIDK VIIYLISCPQ KMYWGVTMVQ LIALLYKDQH VGTLQKLLNL WLEASLSESS EDNESNTSPP EQGSDDSSPI ITSDPTSDSS DGGGGKRNKT LNSTNLERNK KTLMMRGKST ETETSTSSGV STAHTSIDSA DSPKNDKAPL KNKRECPSSQ SEDFGYVTQV ENQESISTSS NEEDQPQLKP VHQKPHTFQK SRYNTGKSRA ATALDKKELR RKKLVKRSKT NTINMKGLLH HLPTDEDIAN ILKEFTVDFL LKGYGILVQD LHSQFLTNIH LQIDTSHFFW LVTYFLKFAT QLELDLEHVS PVLSHEILSY LVFQGVWIYE ELEMSGKIPD FDLKPCLRRL HLVVTAIREF LQAVETYQKM IHLSEDDRLA LLKLQNQITE MEDLRSLFLL LLRQYNPNIQ SRQYLQDLIL TNHNYLLFLD SATKERRSFN MMEHLKQFAT VEIMRQYGLL LESFKENGEF VNNCIFTMMH HIGGDLEHVA TLFQPSILKT FSLIWETDYE ICDDWSDLIE YIIHKFINSP RSNSDLNSSE TCHKLVVDEA EWTEEEKDNL LGYYNQSQFS NDTIANITKK YEKCGVRQKT QLSIIRQLLE QNIINESQYN DFIKVKQQPD RLKETKNIIP NQMDFEETPT DEGIRILREY LCKDNKTKFV LWLQKVLINT CYVKLALANP GEFNNDKALG QPVIYYFALL NLPIPVVPWT VDQTAILKYQ SFVLLLHKLG FYLPIDTGKI FVTIPNFWNA EHVFSMAQQL GPIDPAKLNF DVAIFKGRNR RELFKREITD ITNSIQTGKF SMNDSKQTPT MVRYTPFAHP LSITIPGLEE LTCDLPPPEL SIVDNHVINA NMECSPIHSA CETASIASDL TRMCVSDEEE KTILVIEQK // ID B0DMN1_LACBS Unreviewed; 1147 AA. AC B0DMN1; DT 26-FEB-2008, integrated into UniProtKB/TrEMBL. DT 26-FEB-2008, sequence version 1. DT 19-MAR-2014, entry version 15. DE SubName: Full=Predicted protein; GN ORFNames=LACBIDRAFT_304921; OS Laccaria bicolor (strain S238N-H82 / ATCC MYA-4686) (Bicoloured OS deceiver) (Laccaria laccata var. bicolor). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Agaricales; Tricholomataceae; OC Laccaria. OX NCBI_TaxID=486041; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S238N-H82 / ATCC MYA-4686; RX PubMed=18322534; DOI=10.1038/nature06556; RA Martin F., Aerts A., Ahren D., Brun A., Danchin E.G.J., Duchaussoy F., RA Gibon J., Kohler A., Lindquist E., Pereda V., Salamov A., RA Shapiro H.J., Wuyts J., Blaudez D., Buee M., Brokstein P., RA Canbaeck B., Cohen D., Courty P.E., Coutinho P.M., Delaruelle C., RA Detter J.C., Deveau A., DiFazio S., Duplessis S., RA Fraissinet-Tachet L., Lucic E., Frey-Klett P., Fourrey C., RA Feussner I., Gay G., Grimwood J., Hoegger P.J., Jain P., Kilaru S., RA Labbe J., Lin Y.C., Legue V., Le Tacon F., Marmeisse R., Melayah D., RA Montanini B., Muratet M., Nehls U., Niculita-Hirzel H., RA Oudot-Le Secq M.P., Peter M., Quesneville H., Rajashekar B., Reich M., RA Rouhier N., Schmutz J., Yin T., Chalot M., Henrissat B., Kuees U., RA Lucas S., Van de Peer Y., Podila G.K., Polle A., Pukkila P.J., RA Richardson P.M., Rouze P., Sanders I.R., Stajich J.E., Tunlid A., RA Tuskan G., Grigoriev I.V.; RT "The genome of Laccaria bicolor provides insights into mycorrhizal RT symbiosis."; RL Nature 452:88-92(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS547119; EDR04316.1; -; Genomic_DNA. DR RefSeq; XP_001885207.1; XM_001885172.1. DR STRING; 29883.JGI304921; -. DR GeneID; 6080831; -. DR KEGG; lbc:LACBIDRAFT_304921; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1147 AA; 130196 MW; 9012B2A5C27B73F8 CRC64; MEDEEVIEIT DGESDHEAYV DRRPLLTPII TRVVDALGGF EGDVYRMGDE VYGCLKDLKR LWRKDDTDDE RTVARIYWET RVLPNDLVSI LLATAGKGLV EDKRAIACVD LITAMTWPID MAEELKELDE ELDKATDYTQ LLESHLYYKA ALLKPGVMQA FFGIMLPPLA IFPKERTERD GQIINVVLHL IRNLAFIKDL PANSHTSADQ AELSTLQSKL IQSLQETHTL ELLLTLATNS ENDPLFNSLN NLILEILYLL FRGVKPPSLV VDQAKQPTAN LHRLLEKEDR NRRDLARKAT SRHSRFGTTI AVKLNPNKKP RAGDGVDGGN EADTEHTASS SNRTFVLHRQ QAIHGEAGSI MDVTKQQRSK KGNKVDELTR EDNLSLVARV ALQDLATEFT QGCFNPFLAG LLKDIRSERA KITEKDNLRL LYMTKWFLEF FLLMRVKEQA SRTGEETWSF GLIGEVTERS WIIWVLKRMR EAVEEKPKQW TELQAGIECL TQLLLLIDQL SSSEIDDPVL VEAADVLQQQ LIYNGEVLDI ALDSLRSYKE GKQSLAYLDS SIYLAYALLR MLEKWGKASG SETYVRKKIT RKRKSRKGVG EEDGIPDVEE IEQEDEQVVH ETIFTFEAFE LKFANSEITH TLLKYLSRYK EFSTSENMRR VVSLLHRQVV KAKAEGLFFK VSTLDLFKTI LADQKSFPRE QPYKDLVNLI NFILRQFFKA LEADSFLAIE AFFPKNRGNW KNFSSWEPEK KSKREKKTIE NTRYSPDVEV KKGYSWSDQL GIAIANLVEG GQKELVNWTQ HILTAVIDQR TRIIEETDKK DKEDDAIELD DEEERAALQS KGPSAEALAK ITDFLIPYLS DEHADAATKN PHLKLLFRLS KFFILDEDAE ELEWYVPAGI LMSDLKGTLN VITQFLETPF DLNGKKPSDL LGKKRRRRRR RSPSPISDAD PSEEEPKRKK KTDKKKKEKE EYKSAQFIED SDEEYGDMEA FLEKERAMRQ KALDAAAVAG NRPVAMKPTG TKKRRRKGDE TGKKGKKRKG DLSTEAAVDI DLTDGAPEQS DTSDVEVVDS QDKGITSPLG PSKAAPRPKP RPIAKARASS SRPAAETPLD LSSPRSPQPR DGSEPPERPV VGQRTKRLII SDDEDSG // ID B0W0J0_CULQU Unreviewed; 1412 AA. AC B0W0J0; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 19-MAR-2014, entry version 20. DE SubName: Full=Timeout/timeless-2; GN ORFNames=CpipJ_CPIJ000659; OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Culicini; Culex; Culex. OX NCBI_TaxID=7176; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JHB; RG The Broad Institute Genome Sequencing Platform; RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D., RA Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., RA Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., RA Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., RA Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., RA Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D., RA Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C., RA Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R., RA Galagan J., Birren B., Collins F.H.; RT "Annotation of Culex pipiens quinquefasciatus."; RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS231818; EDS41292.1; -; Genomic_DNA. DR RefSeq; XP_001842224.1; XM_001842172.1. DR STRING; 7176.CPIJ000659-PA; -. DR EnsemblMetazoa; CPIJ000659-RA; CPIJ000659-PA; CPIJ000659. DR GeneID; 6031420; -. DR KEGG; cqu:CpipJ_CPIJ000659; -. DR VectorBase; CPIJ000659; Culex quinquefasciatus. DR eggNOG; NOG297449; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1412 AA; 160875 MW; 9918A467EAF86361 CRC64; MAVLLADIDA TCSNLGHDDG VKYHMEPGTI NGLKHLIWIL KREGEDNEYR RYIGQKKVMQ TDLIPMLMSN FDNPEVADVL LRLIVNLTYP VLLLYNGNYP KDSVGRRNFH RLVEILQTYK EAFAVQQAWI ALGDRLQKVL KMDWAERTEE QELIIERILM LIRNILQVPS CVEAENRYEK AASVHDQVLW ALHQTGILNL VLYILGSEHE HQYHLHSMEI TCLIFREQTA ISLADAQLTR TAAEKNRDEL ELIMSRKREK AHQQVRIPVA RHSRFGGTYV VENMKSISDN NLICHQSLQN ALKLEFDTDK APVKKSFRHV KESGTVERKS AFSVRLFLRQ FCIEILRASY NNLVRQVRRV LERHAGQEAG GGHDDSYLLW AIRFFMEFNR VYKFDLELVT GSYPARRTMY ELVARFKVVS GSPGVPWMDP TVNSAASGNG EVLSDGGFRR HTETRESRWR GVNLQEQKSS ATALLRDKFS IHRNCPQNPP FPSPNRTATV GQGCRSPVPR LECVTRTRCT FRPFSPSAAA LVPVWTHRNP PKTFERARER RSHDRTRLRA ALYQAEAPPS REGSETADST SGWSENPPKF GKLTNCCQNS RKLQARTFKN GQKFVFVIRN AGTPSYGDLQ LIAAFDRNSL NRFAHLRTAN PSKFAANALL LAFRPRNPPK NRTTNLFRDA RVDLEIQSPL RCRPRRRQLE QNGAENPPKS PHEKLPLLPL VHYRSAYGSF LLLLLMLEGP CASCWLASKF VSGRPGVPRQ RLAAKSSAMA AFRRHKKYRT VLEFLVLQKA STEATYGHTA GIFKPSLEAP LSTHGGTQVG HNGGITAQEA GSMQAVLTRG RRSRPWRAAP RPLALFRGGT QAANHHYHGH EAAQPVQHTA GGAQAALPQQ KTTQHTVHTH KAARTLQLRL AATRPHSYDP RWAAHEPLTP AHPSNEDESL WKPWARSPLR RMLVPARRVL QLDQSIQLLL MPNRFFDDEP YDMMIDDDDG GVERDWQQVS LYTVAAGCWP IVGIHRSLVH IRLEGPCSKH RVEQEQKYKF DLELVRVCVV GESSIMCVVV CCATSTKVGD FGKISSKLGK ARPPPPKPGH HTPPEARTEA FLCSYTEPYP QICIRSLIML LLLLQVITRS ESLSVPCFHW IITRIEHYID MMRSDKTRAR LWARRLHVAV QAYREMLQSL NTLQKFQDDK AKDLFAMLQN NVFYVLEYRE VILHLLINYN ENDSTRAYLR DVIETAHMFF KMLEKYCQGT GGVRVQSKKR AKPKRNNNKD KQGKASQQPE MDLESLEGLW LTMAGEVSTC LANQITLPEE DHPIPFDAAS DVPIDDQKYV PAMESFRLAR INPSSLLLFN QLRGDCMIRI HSLLRDGKYE HAIILMRSAR LSHPGHLSVK VWFGEMKPNS CALIRTSDFW DS // ID B0WIS7_CULQU Unreviewed; 996 AA. AC B0WIS7; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 13-NOV-2013, entry version 21. DE SubName: Full=Timeless protein; GN ORFNames=CpipJ_CPIJ007082; OS Culex quinquefasciatus (Southern house mosquito) (Culex pungens). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Culicini; Culex; Culex. OX NCBI_TaxID=7176; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JHB; RG The Broad Institute Genome Sequencing Platform; RA Atkinson P.W., Hemingway J., Christensen B.M., Higgs S., Kodira C.D., RA Hannick L.I., Megy K., O'Leary S.B., Pearson M., Haas B.J., RA Mauceli E., Wortman J.R., Lee N.H., Guigo R., Stanke M., Alvarado L., RA Amedeo P., Antoine C.H., Arensburger P., Bidwell S.L., Crawford M., RA Camaro F., Devon K., Engels R., Hammond M., Howarth C., Koehrsen M., RA Lawson D., Montgomery P., Nene V., Nusbaum C., Puiu D., RA Romero-Severson J., Severson D.W., Shumway M., Sisk P., Stolte C., RA Zeng Q., Eisenstadt E., Fraser-Liggett C.M., Strausberg R., RA Galagan J., Birren B., Collins F.H.; RT "Annotation of Culex pipiens quinquefasciatus."; RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS231951; EDS28654.1; -; Genomic_DNA. DR RefSeq; XP_001848611.1; XM_001848559.1. DR STRING; 7176.CPIJ007082-PA; -. DR GeneID; 6038912; -. DR KEGG; cqu:CpipJ_CPIJ007082; -. DR VectorBase; CPIJ007082; Culex quinquefasciatus. DR eggNOG; NOG257888; -. DR HOGENOM; HOG000008522; -. DR KO; K12074; -. DR OMA; SCEIAND; -. DR PhylomeDB; B0WIS7; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 996 AA; 111450 MW; 8F1924DD4FA56E29 CRC64; MEWLLANPQI NSTFGSLGAV VDEVYLVSED CLVNLEEIIG KLAVEDTTLR TFRRAIGFGQ NVKNDIVPLL VHAKDSKILD PTIRLLVNLT VPAECLLPVD LVSKSEIGRH TIFELNKLLI TSKEAFVDWK TTKAVIDYMK SILEKDSKLS IQNCDSINNC LLLLRNILHV PEVNTPGETK PAHSTSLQNQ ILWNLFTQSV DKLLIYLMSC PQRAFWAVTM AQLVALMYKD QHISTLQKLL SFWFESTLSE SSEDNESNTS PPQQCSGDSS PMLTSDPTSD SSDNGDSLTL GWDHQCTQTT LPIPGSSKMN TSISKDPSEA EQVSRMGTEF PTQIIVARAI KSHQIYHQTM GTTCAAKHPT QPAHPHDPKA PLVTTNSPPG VENSTVVTAI REFLQALETY KKSSHLTKED RELLKTLQLQ IGSTDDLKCL FVLLLRCYNP SLQSKQYLQD LIVTNHSLLL LLDGIRDIPG ANVTDMLSHI RQFATVEIMH QYGLMLEDFR ENGAFVNDCI FTMMHHVGGD LGLMNVLFQP NILKTFSLIW ETEYEICDDW SDLIEYVIHK FINTPQPSPL TLTSTLPDLS SQLLSSNLMS TWTQEDKDSL QWYYVQCKQS KCMVADILRL FEENGNQQKT RVSIIEQLWE QDIVTLSQYD ELMKLENPDY ERNVQTPGFS VASAKSEKMD DDNRPSSKAV DDIQVLRDRL FKENKGKLVV WLQKSLLDCC FVKLNLLSGT VVVMEPVPYH CILQKKSIPI VPWNLEQFNV LSYQPFVLLL HKLGFHLPAD ARKMFVRIPA FWTADILYNI ALKLGPLEKS IIKFDLKHLN KALSMEKQTK SEPFPVSDGV IKPDIYGTLA RSNKSNPVRS GYTPDVTTNW LQVVMRNKAA AESASSTRAM EIPVTPQVIV STGAALHPSN GNTGGGKPAS HPKLAHDLSI IVEAASNDEL PVGEEDDDDE LDRSDGPALA GHDVVSDCET ASVASDLTRM YVSDEEDKHD IVPQIL // ID B0YEB8_ASPFC Unreviewed; 1176 AA. AC B0YEB8; DT 08-APR-2008, integrated into UniProtKB/TrEMBL. DT 08-APR-2008, sequence version 1. DT 09-JUL-2014, entry version 22. DE SubName: Full=DNA repair protein (Tof1), putative; GN ORFNames=AFUB_098620; OS Neosartorya fumigata (strain CEA10 / CBS 144.89 / FGSC A1163) OS (Aspergillus fumigatus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=451804; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CEA10 / CBS 144.89 / FGSC A1163; RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046; RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., RA Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., RA Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., RA Galens K., Fraser-Liggett C.M., Haas B.J., Inman J.M., Kent R., RA Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., RA Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., RA Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., RA Jiang B., Denning D.W., Nierman W.C.; RT "Genomic islands in the pathogenic filamentous fungus Aspergillus RT fumigatus."; RL PLoS Genet. 4:E1000046-E1000046(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS499603; EDP47262.1; -; Genomic_DNA. DR EnsemblFungi; CADAFUBT00009758; CADAFUBP00009583; CADAFUBG00009758. DR HOGENOM; HOG000048676; -. DR OrthoDB; EOG7PGF01; -. DR PhylomeDB; B0YEB8; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1176 AA; 134897 MW; 236EADF236015816 CRC64; MDEEGAPLSE GVQVVDPDVR AHVYSLVTAL GGFNGESADR YVLGDDALAC LRDIKRWLKL YDEKHNRMDV ARCLGEANLV NGDLLPILTL WSTSGQKSKH MSRIALACLE LLVPLTWPLE VHSEMTVNHH RHTPYLQQAQ VLYKRGILSH GSGSILRTII RIGLPSMAVP RSERTTRDEG ILKLMLYFLR NIAVISPNAR LAAEGDEEET SRSATINAFQ NQDAFALLLT MCSNVGEDFS LQDVVLLEIL FHIVKGVNVE KLFMNDAQRK AKRTDELGEL LQKESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QDVLKDSQTT LHKMDQSKKW NKPQIRRRAA EVTANNDFNT PVNINSTATK NLRMFVEEFL DSGFNPLFTH VRKAIEREAD RVMDINTRQF FYTVAWFLEA ERVRRAHQRE KRHLGDTPLK EIEPDSFALV ASVLNQETFV FLNRSMQYSY DNKDVEDLTA EMRCFTQILL TVQEMAQSPL EEDQEIADNI QNRIFYEETT HDRIVAIVRG YKDQGFGYLD ACTELAHVFL RMLEHYSKEN VDMHVRSRRR AKRKAKQAKQ ADIEGDDEEE ASEEEDLMDV ERISKERKFD FRRFAAKFCN QSCVDTFIAF TKYYRELNVD QLKRAHRYFY RIAFKQEMSV LLFRLDIINL FYRMIKGPGA LDSNKPIFKE WEELVRQIIR RMIKKIDQRP ALITELLFSK INSTVFYLEY GHEKQTISAS KRPPAELEVE PREAKTIDEK IRIVVHVMVK DEHTDLVKWV SDVLNSAADE REAWESQEQH SGGQKAPNPM IPVKSDNESC QKAMFSNAKL RLLMSLVRFE RLGMEDVPGA SWVVPSSLNS QELRHTRSII EQCLTEPVTE NSDRDLSQLI RRKSGNNTRR DRDDQMANVD FGSDSEGDDN VPDGPLFPPN PRSRANALEQ LKKQRKKRRK QAGEEEEPDE EDLEARRRAR LENALARQAK IKSDLYIHAS DEETDEEADQ EFFRLEEQRR KEQAERIRKA LLHGVVEEVS ENSRKKSSGR KRQSDQYTAS TADSQSKRQR RLQQTEGLDG NDDLVVAGTE ARSPDSLGQG SPSLKGANDV EDTLVTSEEN ELDFDDDLAF SRNRTRDKVL SAENDDSDTE PPAPDTIDED GEEAAAVAAP PRRRVRAGFV IESDSE // ID B1WBQ6_RAT Unreviewed; 535 AA. AC B1WBQ6; DT 20-MAY-2008, integrated into UniProtKB/TrEMBL. DT 20-MAY-2008, sequence version 1. DT 22-JAN-2014, entry version 25. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=Timeless; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Spleen; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RA Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., RA Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., RA Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., RA Feolo M., Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., RA Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., RA Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., RA Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., RA Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., RA Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., RA Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., RA Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., RA Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., RA Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., RA Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., RA Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., RA Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., RA Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., RA Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., RA Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., RA Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., RA Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., RA Makowski K.A., Bosak S., Malek J.; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BC161845; AAI61845.1; -; mRNA. DR UniGene; Rn.31755; -. DR STRING; 10116.ENSRNOP00000043366; -. DR HOGENOM; HOG000133002; -. DR HOVERGEN; HBG099504; -. DR NextBio; 35564858; -. DR Genevestigator; B1WBQ6; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 535 535 SQ SEQUENCE 535 AA; 62658 MW; D47C46949C1DCFD0 CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDPTVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKRID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQK PEQLAGVGQG RLAQERSTDL AELEVLRQRE VAEKRARALQ RGNRHSRFGG SYVVQGLKSI GERDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLREKA QQHDETYYMW AMAFFMAFNR AAAFRPGFVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDDA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLC DLVETTHLFL KMLERFCRSR GNLMVQNKKK KKKKK // ID B2B5K9_PODAN Unreviewed; 1214 AA. AC B2B5K9; DT 20-MAY-2008, integrated into UniProtKB/TrEMBL. DT 20-MAY-2008, sequence version 1. DT 11-DEC-2013, entry version 25. DE SubName: Full=Podospora anserina S mat+ genomic DNA chromosome 2, supercontig 2; GN ORFNames=PODANS_2_4970; OS Podospora anserina (strain S / ATCC MYA-4624 / DSM 980 / FGSC 10383) OS (Pleurage anserina). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Lasiosphaeriaceae; OC Podospora. OX NCBI_TaxID=515849; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S / ATCC MYA-4624 / DSM 980 / FGSC 10383; RX PubMed=18460219; DOI=10.1186/gb-2008-9-5-r77; RA Espagne E., Lespinet O., Malagnac F., Da Silva C., Jaillon O., RA Porcel B.M., Couloux A., Aury J.-M., Segurens B., Poulain J., RA Anthouard V., Grossetete S., Khalili H., Coppin E., RA Dequard-Chablat M., Picard M., Contamine V., Arnaise S., Bourdais A., RA Berteaux-Lecellier V., Gautheret D., de Vries R.P., Battaglia E., RA Coutinho P.M., Danchin E.G.J., Henrissat B., El Khoury R., RA Sainsard-Chanet A., Boivin A., Pinan-Lucarre B., Sellem C.H., RA Debuchy R., Wincker P., Weissenbach J., Silar P.; RT "The genome sequence of the model ascomycete fungus Podospora RT anserina."; RL Genome Biol. 9:R77.1-R77.22(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CU640366; CAP73084.1; -; Genomic_DNA. DR RefSeq; XP_001911259.1; XM_001911224.1. DR GeneID; 6196107; -. DR KEGG; pan:PODANSg8301; -. DR KO; K10997; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1214 AA; 138150 MW; 1AEB5DCA651D863C CRC64; MEDNEIPNDT VHPEVRAHIN SLVSALGGYS VDSDDDKYKL GDDALEVLRD LKKWIRFYDE KTNRMDVARC LAEANIVCTD LLQILALWPP SDNDSKYRSK VALACYELMV PLTWPIEKDP ETMTVNHHRH LPVLQLAQLN YKRAIINFDA AQILNTAIRV ALPSMALSIG DRTARDQGII KLILYFLRNI AMISPPPGVN YEGDESQISR SALIDAFSFQ DVFLAILTIA SNMGEDFRTE DVIILEILFH LLKRVDSSKL FVSEKRLNKI KTDELTAAMN KEAAMLRSYN KKGPSRHSRF GTMIWVKREN GRTVTVSGQD ALLDPAARER KMDGSKTFKA PRRARKDEAD KELGLPVNLD ERARQQLKDF VSDFLDSGFN PLFLHLQRSI DREASHVLES HKAQFFYLVS WFLEAERVRQ QANKDQKKPA QPVAEDDVNT FNLVAGVLQP EMIITLNRYL DRAYTDKNWP QLTTVMRCFT QILLTIQEMT DSGNEEDEEI ADNLLSNLFY EEKTHDTIAS VARTFKDQGF EYLDACTELT HTFLRILEAY SKQNVDMQVR SRRRTRKKKK AKQAEAVAAG GTNSDAEEDE DLVNPVSDDD DEADARKAEH TSQERKFNFA QFATRFLPQG VVDTFVKFTH FYQDLSPEQL KRAHRYFYRV VFKHEMGTML FRLDIISLFY NMIKGPQPLD SSTVGKSVYK EWEELVKQIL RKCTKKLEER PALFVELLFS KEKQTAFYLE YGYERQTSSV STNPRPGAEL EFKDKMLEKE AQIAIVVGVL LDRNQTEWLE WVKKTLAEAE SERRGWEGEQ EARQSGATTD GEVVVGLLPE APYTVIHPSN DKCRTAMFKN PHLRLLMKLV GFERLAPTLD ETPDSVWIVP GRMSAYDLKE NLNMINKAEF EPPTFEAGEL AEDQLRRKSA GTKAAPRKRA AFDDGDDDDI LDDGEEPLFA AGRLKSINPT GDRPKKLRRK RMTINSDGEE VEEVREIDDE EAAARAKARK LKQLEKLRKI KSEVYVRASD DESDEEADKE FFAREEERRQ KTMAAYGGPA KEKEKEKPTG VEKSAWERLL DGDDSEEDDE DAVVERPKPK KAVKRGGKRK SDAADLGDDE DVDMDRDDDD EENTADDESE RSSSAVSPAP AKRAAKKRKP SKKPVDDDGD EEMQSATQTS EKGVGDKDKG GGEEDTDDDM PVAAPVRARP RVRAGFIVDS SDEE // ID B2G469_ZYGRO Unreviewed; 1208 AA. AC B2G469; DT 10-JUN-2008, integrated into UniProtKB/TrEMBL. DT 10-JUN-2008, sequence version 1. DT 03-SEP-2014, entry version 18. DE SubName: Full=Topoisomerase 1-associated factor 1; GN Name=Zr_TOF1; ORFNames=Zrou_1p86; OS Zygosaccharomyces rouxii (Candida mogii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; OC Zygosaccharomyces. OX NCBI_TaxID=4956; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CBS 732; RA Gordon J.L., Wolfe K.H.; RT "Zygosaccharomyces rouxii homologs of Saccharomyces cerevisiae RT chromosome III."; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AM989980; CAQ43378.1; -; Genomic_DNA. DR KEGG; zro:ZYRO0F16742g; -. DR KO; K10997; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Isomerase. SQ SEQUENCE 1208 AA; 137326 MW; DC52BD54C199EBC2 CRC64; MVDPNDLSTT VLKARIALLA TAIGGPDYTS NLDPPPYKLG DDCLACLKDL KRWFRLVDEN QNRWDVAIAA AEYRILQDDL IPILIDWENK CSLAHKLNKD SYNKEYHDNI ALLCVQLIVI MTCPQVLTDQ STARQVAVYS ELKKRQLEYK RDILMAERGK VLRAIVRLAS KVIKIDRIDR TPRDNVVLRL IINLFRNVVA IEPGELNITK KKQISTKGIN SVDTLPPGVS MDDISLNTVI AAFQKNKVLG LVLTLASSMS VEFEQDFINT PLMELMFYLT KDIPPESLVG SDKRQESHND SDRVSSTGAE LLNLLDKENN LKKNVIKNTS TRHSRFGALL SIQTPDSGRL TVSGGGQNLL DDSTALNKLD SRKKWNKRSV QHRDDIVAEG LPNSLLNSGT KSGFSLDSTM MKFAHFIDDF IDSSFNTLLH SVTNQYTGDQ DQMTTLEKTE YLLFFSWFVK YQREKCNKDL AADISSVDSA LQETSFILVS TILRTGYELK NWAAVHAGMI AFNELLLLIS SIQDPYNSDE VEFIVGKLFS DDRIQLLTSL PKTAFRYSLQ YMKSCVELVH TVLETLEQYT KDNSLTVTRK TKSTKRKEIT EEQVTVLMDS QGIGRDEALD LLNPSFKKME FNFMKVLKKF CVESIVDTYI NYLQRFRELN DTEIKKAIYF LHRVFVQASE QSILFRLDLI MLLKDMLAPD GVSRKSRVRK HIEQFSNYFL YKLKKRLKSS PSWYIGLLFP LLYGSEVGYF QKYGEVKPHK ENNYHAVPPS RFKNIEDEEQ LPESVLKDMK FGILVSTLID DGKEELLISL ISHMQVALDR FKSWLSVNVQ HERETENSPD EILGSENFNG SKPFIFDKDF RTLLDLIGYS LPLNVEEQCK LPGNVEIDSL QDSLELVKKH LATPFQTPNG LPSSSYLLRP KLNASGSNAE DDGWHGDDEY DYEEPGIVPD GQQLFVTDDD AYFEELEKDM GDKLSGKETD KDKGIAKSKK KPKAKTKRSR KQKDNSSLPL HDIGEQPEKT KQRKDVLSKD FISDSEEEED NINPLFFENE MYMRWLLDKH RGQLPEERYA LFGKFSAERI ANNGSLVNDY SALFGGAVPD LEDLRSSETT SDSPDRTLIS LSRRVAAEIE KASEEPEPQN THETDLSDSE VSMDDFPVST SNADARTSPL TKRPTTDLSS SEDDNSTGHA NLSRKKRKVL FADDEDDD // ID B2WEG7_PYRTR Unreviewed; 1169 AA. AC B2WEG7; DT 01-JUL-2008, integrated into UniProtKB/TrEMBL. DT 01-JUL-2008, sequence version 1. DT 14-MAY-2014, entry version 21. DE SubName: Full=Drug resistance protein MdrA; GN ORFNames=PTRG_08540; OS Pyrenophora tritici-repentis (strain Pt-1C-BFP) (Wheat tan spot OS fungus) (Drechslera tritici-repentis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; OC Pleosporaceae; Pyrenophora. OX NCBI_TaxID=426418; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Pt-1C-BFP; RX PubMed=23316438; DOI=10.1534/g3.112.004044; RA Manning V.A., Pandelova I., Dhillon B., Wilhelm L.J., Goodwin S.B., RA Berlin A.M., Figueroa M., Freitag M., Hane J.K., Henrissat B., RA Holman W.H., Kodira C.D., Martin J., Oliver R.P., Robbertse B., RA Schackwitz W., Schwartz D.C., Spatafora J.W., Turgeon B.G., RA Yandava C., Young S., Zhou S., Zeng Q., Grigoriev I.V., Ma L.-J., RA Ciuffetti L.M.; RT "Comparative genomics of a plant-pathogenic fungus, Pyrenophora RT tritici-repentis, reveals transduplication and the impact of repeat RT elements on pathogenicity and population divergence."; RL G3 (Bethesda) 3:41-63(2013). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS231623; EDU51459.1; -; Genomic_DNA. DR RefSeq; XP_001938872.1; XM_001938837.1. DR EnsemblFungi; EDU51459; EDU51459; PTRG_08540. DR GeneID; 6346826; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1169 AA; 133247 MW; CF30602098AA5513 CRC64; MPQTTLDDWA QDTVNPEVRA HVSSLISALG GIGDDGTYSL GHDALLCLKD LRKWLKFADQ QNNRRDVARC MAEANLVKGD LLEILAKIAP AAMESAWKHK IAVATLELLV PLTWPFEIDP TEATVNHHRH GPYIQLAQIG YKRAILQFDR DRILQTAVKI ALPSMAVPLR ERSPRDEGII RIALYFIRNI AMLSPPNSAP MDIDEAEVSR SATIDAFQEQ DIFQVLLSIA SSIGEDFVSQ DVIVLEILFF LLKGIDAEKL FMEDKKLNTK NADELKSLIQ KEKAMLAGHA RNAPTRHNRF GTMIWVKRDD EKVTTISGQD VLGKAQASME KMDATKKWNK PRRPGRKQDG NEEREEFDLP VSLSTSARKH IKAFVEEFLD SSFNPLFLHL RKAIERETER VETRHSRQFF YLVSWFLKAE CARRRTMKER AADPKSPEVL SAEDESYGLV AEVMNQETFI LLNRFMQTSQ DEKAWRDLNA GLKCFTQILL TVHEMSESVL EDDQEIAENI QNRIFYEEST HDRIVTILRS YKDQGFGYLD AVTELSHVFL RMLERYAKQN VDMQIRSKRR ARNIKKKKAD KQGEEGEEEG HVSETEDIQQ AQKTVSERKF DFTRFSAKFV NQSSVDTFVA FAKYFNDLNT EQLKRAHRFF HRVAFKMELG VLLCRVDILQ LFNKMIKGPG GLDPESPAYR EWDDFVRHFF RHVVKRVQER PELVVEMLFS KIPATIFFLE HGYDREVTVK APRAPAELEV KPGIELPEQI GVAVSVLVNQ SKSDAIRWVR EVLTSAAEER KAWEEAGEAQ KMLTADVQPP EGEMTAENTE AETTKPPSIL IKHDTEERRI AMFKDNKLRL LMTLVGFERL GEHHDPDATW IVPSSLTSAQ LQEAIDLIRK FEFDPPTYED GKAPEDMLRS KTTVAQPSTR RAEFDDDSDG IDHQSEEDHG EYAQGGATTR EADGPRKKLK RRRRERTPRE LDDDEKERRA EARRKKELEK QAAALSTTYV HDSDDEDWDA EKDAAFFARE EALRQENLKA YKKSHILGTV EPIASKKRKA DAPAKKTKRR KAPFDDSDED MGDAESSRAQ SEAAGDILDD DDENEEETTD TPLSSQNAVA AAVSEASTPR KLSENASKTT DVAMVNADTD DDEEDEMPVA RRPAARNMRA GFVIDSDSE // ID B3F207_SHEEP Unreviewed; 1226 AA. AC B3F207; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 21-SEP-2011, entry version 10. DE SubName: Full=Timeless; OS Ovis aries (Sheep). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Caprinae; Ovis. OX NCBI_TaxID=9940; RN [1] RP NUCLEOTIDE SEQUENCE. RA Dardente H., Hazlerigg D.G.; RT "Establishing the sheep as an animal model to study the molecular RT mechanisms of circadian rhythms."; RL Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EF494244; ABS44880.1; -; mRNA. DR RefSeq; NP_001121625.1; NM_001128153.1. DR UniGene; Oar.819; -. DR GeneID; 443226; -. DR CTD; 107698; -. DR HOVERGEN; HBG079258; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1226 AA; 141675 MW; 553F93FCF6F7476D CRC64; MMNCELLATC SALGYLEGDT YHKEPDCLES VKDLIRYLRH EDETRDVRQQ LGSAQILQSD LLPILTQHRQ DKPLFDAVIR LMVNLTQPAL LCFGSLPKEP SFRHHFLQVL AYLQAYKEAF ASEKVFGVLS ETLYELLQLG WEERQEEDNL LIERILLLVR NVLHVPADLE QEKRIDDDAS VHDRLLWAIH LSGLDDLLLF LASSPAEQQW SLHVLEIISL MFRDQNPEQL AGVGQGRLAQ ERRTDVAELE VLRQREMAEK KTRALQRGNR HSRFGGSYII QGLKSIGERD LVFHKGLHNL QNYTSDLGKQ PRRVPKRRQA ARELSVQRRS ALNVRLFLRD FCSEFLENCY NRLMGSVKDH LLREKAQQHD ETYYMWALAF FMAFNRAASF RPGLVSETLS VRTFHFIEQN LTNYYEMMLT DRKEAASWAR RMHLALKAYQ ELLATVNEMD VCPDEAVRES SRIIKNNIFY VMEYRELFLA LFRKFDERCQ PRSFLRDLVE TTHLFLKMLE RFCRSRGNLM VQNKRKKRRK KKKALDQSVA SGNAPYSPEE LEAMWPSLAE QLQCRAQDSE LSLDSVIPFD AASEVPVEEQ RAEAMVRIQD CLLAGQAPQA LSLLRSAREV WPERDVFGAQ DISPEEEIQL LKQILWAPLP RQQGLEEQGA EEDDEEEEEE EELEVVQVSE REFNFLDYLK RFANSTVLRA YLLLLRSYKQ NSAHTNHCVV KMLHRLAHDL KMEALLFQLS LFYLFNRLLS DPAAGAYKEL VTFAKYILGK FFALAAVNQK AFVELLFWKN TAVVREMTEG YGTLDGGSSS RRLPGWSPEE EAQLRELYLA HKDVEGQDVV DTILAHLKTA PRTRRQVIHH LVRLGLADSV KDFQRKGTQI VLWTEDQELE LQRLFEEFQD SDDVLGNIMK NITAKRSRAR IVDKLLSLGL VAERRELYKK RRKKLAPSSL PNEEESLHDF CQEDLEEEEN VPEKENEEDE EKEEGSEPEQ AQGGSVLSAE YLGQSLHQEG FSAPLLWLQN CLIRAADDRE GAGCSQAVPL VPLTEENEEA MESEQFQQLL RKLGVRPPAS GQETFWRIPA KLSPTQLRRM AASLSQAEEE EKLQLGLESK VPGEPGLEEE HQQEEEHQQE EEHQQEEEHQ QEEEHQKEHR AHALRTLLLA RKKKAGLVSP EEEGTNGGKE QLIMAPKKRQ LLDSDEEQEE DKAPELGVPG IRKKKRFQIE DDDESD // ID B3FY27_DROVI Unreviewed; 164 AA. AC B3FY27; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 03-OCT-2012, entry version 4. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila virilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7244; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=1051.87; RX PubMed=18482259; DOI=10.1111/j.1365-294X.2008.03796.x; RA Morales-Hojas R., Vieira C.P., Vieira J.; RT "Inferring the evolutionary history of Drosophila americana and RT Drosophila novamexicana using a multilocus approach and the influence RT of chromosomal rearrangements in single gene analyses."; RL Mol. Ecol. 17:2910-2926(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU545840; ACD67951.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18375 MW; 527519FFE23D661D CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPETH AHFLMPRLQP GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID B3FY33_9MUSC Unreviewed; 164 AA. AC B3FY33; DT 22-JUL-2008, integrated into UniProtKB/TrEMBL. DT 22-JUL-2008, sequence version 1. DT 03-OCT-2012, entry version 4. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila novamexicana. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=47314; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=1031.00, 1031.04, 1031.08, and 1031.12; RX PubMed=18482259; DOI=10.1111/j.1365-294X.2008.03796.x; RA Morales-Hojas R., Vieira C.P., Vieira J.; RT "Inferring the evolutionary history of Drosophila americana and RT Drosophila novamexicana using a multilocus approach and the influence RT of chromosomal rearrangements in single gene analyses."; RL Mol. Ecol. 17:2910-2926(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EU545846; ACD67957.1; -; Genomic_DNA. DR EMBL; EU545847; ACD67958.1; -; Genomic_DNA. DR EMBL; EU545848; ACD67959.1; -; Genomic_DNA. DR EMBL; EU545849; ACD67960.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18307 MW; 51F8AF040F88AC1A CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFVMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID B3LPB2_YEAS1 Unreviewed; 1238 AA. AC B3LPB2; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=SCRG_03400; OS Saccharomyces cerevisiae (strain RM11-1a) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=285006; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=RM11-1a; RG The Broad Institute Genome Sequencing Platform; RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., RA Cuomo C., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., RA Kleber M., Mauceli E.W., Brockman W., MacCallum I.A., Rounsley S., RA Young S.K., LaButti K., Pushparaj V., DeCaprio D., Crawford M., RA Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., RA Larson L., Luoma S., White J., O'Leary S., Kodira C.D., Zeng Q., RA Yandava C., Alvarado L., Pratt S., Kruglyak L.; RT "Annotation of the Saccharomyces cerevisiae RM11-1a genome."; RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH408049; EDV12507.1; -; Genomic_DNA. DR ProteinModelPortal; B3LPB2; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141120 MW; CF8FEC33EE0088E9 CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEGDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGVL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID B3LX42_DROAN Unreviewed; 1584 AA. AC B3LX42; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 38. DE SubName: Full=GF17582; GN Name=Dana\GF17582; ORFNames=Dana_GF17582, GF17582; OS Drosophila ananassae (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7217; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14024-0371.13; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH902617; EDV41642.1; -; Genomic_DNA. DR RefSeq; XP_001953059.1; XM_001953024.1. DR ProteinModelPortal; B3LX42; -. DR STRING; 7217.FBpp0120774; -. DR EnsemblMetazoa; FBtr0122282; FBpp0120774; FBgn0094600. DR GeneID; 6500366; -. DR KEGG; dan:Dana_GF17582; -. DR FlyBase; FBgn0094600; Dana\GF17582. DR eggNOG; NOG297449; -. DR InParanoid; B3LX42; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B3LX42; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR Gene3D; 3.30.40.10; -; 1. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR017907; Znf_RING_CS. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00184; RING; 1. DR SMART; SM00717; SANT; 1. DR SUPFAM; SSF48371; SSF48371; 3. DR PROSITE; PS00518; ZF_RING_1; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 4: Predicted; KW Complete proteome; Metal-binding; Zinc; Zinc-finger. SQ SEQUENCE 1584 AA; 182202 MW; ACCCF88493224836 CRC64; MSILLANIDA TCAALGYSDG NKYQAEPDAA DALKHLIWIL RRDLDNHEYR RHLGRAKVLQ TDLVYMLPDY IHHEELSDLL IRLLVILTNP TLLLFRDGPP SDNHGRKVFM ELIDILQGYK AAFARDKIWT SLFEKLKRAL EIRSMAELVN PGEMRDEVAE IRKEDSSDTS ADGQPIAESS YFSCLVCMRT ARSPRVSFCG HHFCYRCIRH WIKTQGSKVK CPYCQSRIGE NTLIAIRYPG SGLPKHTKCK SLEEHRMRIL KSVDYINELA QLPAAGMFVR GYIEYPPEPF PRVRPLPPQL LVQVPDYPIR RTFSDYTVVQ RTIMVIIMAF AIRSEEQNLL IERILVLMRN VLQVPANPEA ECRADNDASL HDQVIWALHQ TGMLDLVLFI ISSPDEEQFH LHGLEILCLL YREQSAESLA DASLQRSVSE KQRDQQELMA ARRRERARRQ AKPPPGRHSR FGGTYVIRNM KSVSDRDVIC HQALERVSSI DFDREKQQQK RSHRHIKEEA QVTRRSAFTV RLCLREYCIE VLRSAYNTLV RQVRRVLERN AGSSSHDDSY LLWAIRFFME FNRLSGLQLQ LVSESLSVQC FHWVLTRMQH DMDMIVSDKK QARLWAKRLH VALLTFRELL QSLLALQKLK DDSNARALFD MLLNNVCYVL EYRETVLHLL MNYNEAHSTK VFLRDVVETA NVFIKMMERF CQDSVLVQDK RRGGAGGRRK KPPTAKSKPS AIPQPTEEEL SSKWAELATE VCALVAAELE IQEDELPVPF DAASEKSIDD QREDCMIRIN KLLRSEKLDQ AVALLRAARE VWPENEVFGA ISAAPEDELL LLREIFMHNI TTVEPQEMEN GHEDGQDEDE EDDELENEEF GDQDNGLTEK TFKFDDFARR LLHPKIVRAC TVVLTDWASI PTRSLKAAVT ILHRIAYGCK CSGMLFQAKL FRIFQQVFSV ERDAHQEELR RLAIFVVRKF VEVAPSNPKI YAELLFYKGI REANELETGY CDAYEAGTKG TWTEEQESEL RFLFEENQRN PETDKDVIDW ILDNLADKTR TRRGILKKLK EMGLLFKAPT KRSTKSALGG KNLWQPEEDE ELRSLYDQHR TEPDCLDRIV GEFEERRSKQ QIIKRMLQIH LIADKSEILP PKSSKGRGKG KAKKHSENGS DFEDMMEEPM EFEAEAGDRP KAVRKTIKKS KSKPKPKKRQ VVRTPLDVGA VKALLAQVDA EKFKSAIEWL QECLQDASED MEEPGEEDDG VPLLALMDDQ RDALEDGDFQ KVLVALGMQP PIAGMENYWR IPTHLNATDL KIRSKILAGE DVDEDEQEED EEDEDEDDKE ESEEEDFLEK HSRQRQENIA AEQQRKLDSI MFSKSDDETE ERAPPKAKAK NKEKKVKKQP KTKTKKPQDS DASKEEREKP YTTDLFDQLK AKRATKIKLG DMVLNESTKA AQEADDDAFN FNSEDYRARL LELEDEENEK KDDDGDADSD EEEQNKENTT NKSLQQPPRA RRVNVIDSDS DNDDNDDDDA AGGALLADKT NKRPRSDEDD AGQDEDDSDE EANFLARKKP AKVDEEPAKR RRLAIIDDDG EDDF // ID B3MP29_DROAN Unreviewed; 1404 AA. AC B3MP29; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 27. DE SubName: Full=GF14670; GN Name=Dana\GF14670; ORFNames=Dana_GF14670, GF14670; OS Drosophila ananassae (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7217; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14024-0371.13; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH902620; EDV31195.1; -; Genomic_DNA. DR RefSeq; XP_001961974.1; XM_001961938.1. DR STRING; 7217.FBpp0117862; -. DR EnsemblMetazoa; FBtr0119370; FBpp0117862; FBgn0091697. DR GeneID; 6497491; -. DR KEGG; dan:Dana_GF14670; -. DR FlyBase; FBgn0091697; Dana\GF14670. DR eggNOG; NOG257888; -. DR InParanoid; B3MP29; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B3MP29; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1404 AA; 156834 MW; 886AEE55EBFDD224 CRC64; MDWLLATPQL HSAFSSLGYL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTDPK STKSVVEYMK HILESEPKLS PHKCDQINNC LLLLRNILHI PETHAHCVMP MMQSNGPHGI SMQNTILWNL FIQSIDKLLL YLMTCPQRAF WGVTMVQLIA LIYKDQHVST LQKLLNLWFE ASLSESSEDN ESNTSPPKQG SGDSSPMLTS DPTSDSSDNG SNGRGMGGGL GKREGTAATL QEVSRKGQEY QNAMSRVPAD KPDSSEAASD ITSELPGSPE QSQPAGESMD DGDYEDAQGS QQDLHGDEEE DEDEDEVDEE KYMRVESSAE PLNLTQQSNP QPADNVNHTT TTVSTDSPTG NAEEEPFKPP PPLPVRASTS AQAQIQQLND AVYTTPHISA VKLGQKSPHA GQLQLTKGKC CPQKRECPSS QSELSDCGYG TQVENQESIS TSSNDDDGPQ GKPQHQKPPC NTKPRNKQRT IMSPQDTKEL RRKKLVKRSK SSLINMKGLV QHTPTDEDIS NLLKEFTVDF LLKGYNYLVE ELHQQLLSNA KVPIDTSHFF WLVTYFLKFA AQLELDMEHI DTILTYDVLS YLTYEGVTLC EQLEMNARQE GSDLKPYLRR MHLVVTAIRE FLQAIETYNK VTHLGEDDRA HLRQLQLQIS DMTDLRCLFV LLLRRFNPSI HSKQYLQDLV VTNHILLLIL DSSARIDGGQ TVRLSEHISQ FATLEVMHYY GILLEDFSNN GEFVNDCIFT MMHHIGGDLG QIGVLFQPII LKTYSRIWEA DYELCDDWSD LIEYVIHKFM NTPPKSPLTI PTTSLTEMTK EHNQEHTICT WSQEEMDTLY WYYVQSKKNN DIVGKIVKLF SNNGNKLKTR ISIIQQLLQQ DIITLLEYDD LMKFEDAEYQ RTLLTTPTSG TTESGIELKE CAFGKPSDDV QILLDLIIKE HKSQHLVWLQ KLLLECCFIK LTLKGDIKIP EGNRIMEPVA YHCICKQKSI PVVQWNNEQS TTMLYQPFVL LLHKLGIQLP ADAGSIFARI PDYWTPETMY GLAKKLGPMD KLTLKFDACD LEDATAASPS RYHTGPRNSL SSVSSLDVDL GEPEDLAIIP EVDPAIEKAH AMSSTPSPTE IFAVPKTKHC NSIIRYTPDP TPPVPNWLQL VMRSKCNQRP TGDPSDGVTS SATTVNEDEG LGKSFTAGTS QSGSSSMGAV NSTTTTLGCL SMMNSFMGSQ NENSNSPGGG GTVASLPMAA LMSAKAMGGG GAVGITDPEV DASMKTSFER PETTGAHFSR ANNLDQEYSA MVASVYEKEK ELLNSDNVSV ASDLTRMYVS DEDERHEFRV PHYH // ID B3N332_DROER Unreviewed; 1418 AA. AC B3N332; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 24. DE SubName: Full=GG24435; GN Name=Dere\GG24435; ORFNames=Dere_GG24435, GG24435; OS Drosophila erecta (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7220; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14021-0224.01; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH954177; EDV57631.1; -; Genomic_DNA. DR RefSeq; XP_001968572.1; XM_001968536.1. DR EnsemblMetazoa; FBtr0144489; FBpp0142981; FBgn0116567. DR GeneID; 6541612; -. DR KEGG; der:Dere_GG24435; -. DR FlyBase; FBgn0116567; Dere\GG24435. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B3N332; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1418 AA; 157525 MW; 4659C06E7EB95107 CRC64; MDWLLATPQL YSAFSSLGGL EGDTYVVSPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVKSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAR STKSVVEYMK HILESDSKLS PHKCDQINNC LLLLRNILHI PETHAQCVMP MMQSTPHGIS MQNTILWNLF IQSIDKLLLY LMTCPQRAFW GVTMVQLIAL IYKDQHVSTL QKLLSLWFEA SLSESSEDNE SNTSPPKQGS GDSSPMLTSD PTSDSSDNGS NARSIVGGMR EGASATLQDV SRKGQQYQNA MARVPADKTD GSEEASDVTG NDSEQPGSPE QSQPSGESMD DKDYEDQRRS QLHENGELDK NEDKVEKEEC LLLAPATEPL NLSQQPADKL NSTTNPTSSP PQGCVGHEPF KAPPPLPVKA STSAPAPMQQ FNATHVTAVD LGQKSPHAGQ LQLTKGKCCP QKRECPSSQS ELSDCGYGTQ VENQESISTS SNDDDGPQGK PQHQKPPCNT KPRNKQRAVM SPMDKKELRR KKLVKRSKSS LINMKGLVQH TPTDDDISNL LKEFTVDFLL KGYSYLVEEL HIQLLSNAKV PIDTSHFFWL VTYFLKFAAQ LELDMEHIDT ILTYDVLSYL TYEGVSLCEQ LELNVRQEGS DLKPYLRRMH LVVTAIREFL QAIETYNKVT HLNEDDKAHL KELQLQISEM SDLRCLFVLL LRRFNPSIHS KQYLQDLVVT NHILLLILDS SVKLGGGQSI RLSEHIAQFA TLEVMHYYGI LLEDFSNNGE FVNDCIFTMM HHIGGDLGQI GVLFQPIILK TYSRIWEADY ELCDDWSDLI EYVIHKFMNT PPKSPLTNPT TSLTEMTKEH NQEHTVCTWS QEEMDTLYWY YVQSKKNNDV VGKIVQLFSN NGNKLKTRIS IIQQLLQQDI ITLLEYDDLM KFEDAEYQRT LLATPTSGTT ESGIEIKEGA YGKPSDDVQI LVDLIIKENK AHHLLWLQRI LIECCFVKLT LRNGFKSPES FKHIMEPVAY HCICKQKSIP VVQWNNEQST TILYQPFVLL LHKLGIQLPA DAGSIFARIP DYWTPETMYG LAKKLGPLDK LNLKFDANEL EDGTPTTPLR YRHTGPRNSL SSVSSSVDVD LGESEELALI PEVDADVEKA HALASLPSPS EIFAVPKTKH CNSIIRYTPD PTPPVPNWLQ LVMRSKCNQR AGPAADLSDC VGSSATTVDD EGLGKSISTP TSQETRTSMS TANVTTTLSL TMLNTFMGSQ NENSSSSGCG GTVSSLSMVA LMSTGVTGGG GGQDGGGGQD DGGGQDGSGG SGDDGVGDVG GGSSGLDMDA DAFEGNGSHF PRANNLDQEY SAMVASVYER EKELNSDNVS LASDLTRMYV SDEEDRLERT EFRLPHYH // ID B3P181_DROER Unreviewed; 1389 AA. AC B3P181; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 27. DE SubName: Full=GG19468; GN Name=Dere\GG19468; ORFNames=Dere_GG19468, GG19468; OS Drosophila erecta (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7220; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14021-0224.01; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH954181; EDV49270.1; -; Genomic_DNA. DR RefSeq; XP_001980312.1; XM_001980276.1. DR EnsemblMetazoa; FBtr0139522; FBpp0138014; FBgn0111671. DR GeneID; 6553629; -. DR KEGG; der:Dere_GG19468; -. DR FlyBase; FBgn0111671; Dere\GG19468. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B3P181; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1389 AA; 159698 MW; 691139C7176E6E5E CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDVA EGLKHLIWIL RRDLDNHEYR RHMGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILSNP TLLLYRDGAP KDNHGRKVFM ELIDILQSYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGGGA SRKKKQAETK SKPPAAPQPT EEELSTKWAE LATEVCSLLS SELGMPEDEQ PIPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MYNITTVESE DKENEKEQKQ DEDEVEDDDL DNEEYGEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL RAAVTILHRI AYGCKCSGML FQAKLFRIFQ QVFSVERDVH QEELRRLAIF VVRKFVEVAP TNPKIYAELL FYKGIREANE LESGYCDAYE AGTKGAWSEE QELELRFLFE ENQRNPETDK DVIDWILDNL VDKTRNRRTV LKKLKELGLL FKAPTKRSTK SAQSGKNVWQ PEEDDELRSL YDQHRIEPDC LERIVHEFAE RRTKQQIIRR MLQIHLIADK SEILPAKKGR GKGKPKQEQP EMEGDGDDFA EEPMFQEQGY KKPKAMPKKA QKRQVVRTPL DVGTIKALIG QVDSEKYQSA IEWLQECLQD ASEDTEEAAE DDDGVPLLPL MQDQKDAMED ADFQKVLVSL GMQPPISGME AYWRIPIYLN SADLQLRSKI LAGEEADVEP EDEAADDEYE GEPDEGSEEE EDFLEKHSRQ RQENIATQQQ RKLDSLMFNQ SDDETEQRAP PKPMGKPKAS EKKAKRKVKD KAKESKDSDE DGADEAELEK PNTDDLFNQL RAKRSTKIKL SDMALNESTN AAQEADDDAF NFNSEDYRAR LLELEDEEKS AEDADENGGG KENITNKSLQ RARRVNVIDS DSDNDDDGAL PADKTNKRPR SDDDRDDEDG GAGHMDANAE EDSDEEANFL ARKKPAKVDG EPAKRRRLAI IDDDDEDDF // ID B3RPI9_TRIAD Unreviewed; 949 AA. AC B3RPI9; DT 02-SEP-2008, integrated into UniProtKB/TrEMBL. DT 02-SEP-2008, sequence version 1. DT 14-MAY-2014, entry version 20. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=TRIADDRAFT_53559; OS Trichoplax adhaerens (Trichoplax reptans). OC Eukaryota; Metazoa; Placozoa; Trichoplax. OX NCBI_TaxID=10228; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Grell-BS-1999; RX PubMed=18719581; DOI=10.1038/nature07191; RA Srivastava M., Begovic E., Chapman J., Putnam N.H., Hellsten U., RA Kawashima T., Kuo A., Mitros T., Salamov A., Carpenter M.L., RA Signorovitch A.Y., Moreno M.A., Kamm K., Grimwood J., Schmutz J., RA Shapiro H., Grigoriev I.V., Buss L.W., Schierwater B., RA Dellaporta S.L., Rokhsar D.S.; RT "The Trichoplax genome and the nature of placozoans."; RL Nature 454:955-960(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS985242; EDV28195.1; -; Genomic_DNA. DR RefSeq; XP_002110029.1; XM_002109993.1. DR STRING; 10228.JGI53559; -. DR EnsemblMetazoa; TriadT53559; TriadP53559; TriadG53559. DR GeneID; 6750695; -. DR KEGG; tad:TRIADDRAFT_53559; -. DR eggNOG; NOG328380; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 949 AA; 111497 MW; 531D003BED290E38 CRC64; MGNVTIKDLI RFLRRDDDNQ VVRRQLGKSF IIKNDLIPII KCHWKDAELL SLTIRLMVNL TQPAIVCFDG KIPKKDQNQS RYWLEIEKYL HAYKQAFNDS DLWAILTQQL GKTLQIPVDD RDDDDLLFME RLLLLIRNLL HVPQDDNQEN ATNSDASLHD QLLWQMHSSG MNDLLIYIAS SPHETMWTLH VLEMISLMLR DKSGALLART EDTKTEKKAG SRFFKAFRVN FCHVVINQIL RLKFRQLKVA KDVAEAERRR SEYNISGRHS RFGGSFWVKD MKGISENNIV YHRPLANAKK MSFDCNKSIP RVPKRKLPAV EHARVRESPL VIRLSLKTFC VQFLDYCYNS LMNNVRNKLM HNKSQQNDET YYFKMMNETL SMPIFHFTCQ NIYNAYDGLI SNKEDSIPWA RRMHYVVSAY KELLLNVIAM EQIEDHCLNE NAKIIKSNIL YMPEFREIPL MLLTKYDPTR QTRSYLMEII TVTHIYLKMI EKQCSKNGQV MVKEKKRKMK KKSKKDSASK QLTAEWENLS KEITHTLSTF ENLEIFIPAL DGVPISELPG AAKEEIRNCL VESRYSEAIA TLRICRNKLP DKVEDFGQNN ANNEEELLCL KNIYIAKEED FVLQNGVEKN FNLMNYLKKF TSSKVLRHYV DLLSTYDKND DSVNHYIVKW FYRIAHDFRM HAMLYQLRLF LIFNKILSEP PLDRYKELVT FVNYILSRFF ETTKSNPVVY VETLFWKSAG DCYEITEGYG SLSKEKEERK TKGFWSEEEE SKLIELYRKH EDSDDIIGNI LSEFVEFSDK GRAQIRRKLL TSGTVTDRDR LRKRKKSAPV PGREFNHESL EEYEIEDQQT DKDADVDVEE LHDLINDVIT TELDNINSKN INPIEKREII EEINFPKSFM SDDSSSNEEE MEDDVNTIKR DASNDSDNER IMMKRKKKLR QILDSDDDD // ID B4DL70_HUMAN Unreviewed; 705 AA. AC B4DL70; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 22-JAN-2014, entry version 19. DE SubName: Full=cDNA FLJ58786, highly similar to Timeless homolog; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Tongue; RA Wakamatsu A., Yamamoto J., Kimura K., Ishii S., Watanabe K., RA Sugiyama A., Murakawa K., Kaida T., Tsuchiya K., Fukuzumi Y., RA Kumagai A., Oishi Y., Yamamoto S., Ono Y., Komori Y., Yamazaki M., RA Kisu Y., Nishikawa T., Sugano S., Nomura N., Isogai T.; RT "NEDO human cDNA sequencing project focused on splicing variants."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AK296869; BAG59432.1; -; mRNA. DR UniGene; Hs.118631; -. DR ProteinModelPortal; B4DL70; -. DR HOVERGEN; HBG079258; -. DR NextBio; 35472971; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 705 AA; 80484 MW; 95BA79B177266ACD CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHHQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLAISSA EEQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADF AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL NTVPRTRKQI IHHLVQMGLA DSVKDFQRKG THIVLWTGDQ ELELQRLFEE FRDSDDVLGH IMKNITAKRS RARIVDKLLA LGLVAERREL YKKRQKKLAS SILPNGAESL KDFCQEDLEE EENLPEEDSE EEEEGGSEAE QVQGSLVLSN ENLGQSLHQE GFSIPLLWLQ NCLIRAADDR EEDGCSQAVP LVPLTEENEE AMENEQFQQL LRKLGVRPPA SGQETFWRIP AKLSPTQLRR AAASLSQPEE EQKLQPELQP KVPGEQGSDE EHCKEHRAQA LRALLLAHKK KAGLASPEEE DAVGKEPLKA APKKRQLLDS DEEQEEDEGR NSAPELGAPG IQKKKRYQIE DDEDD // ID B4G5M5_DROPE Unreviewed; 1390 AA. AC B4G5M5; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 28. DE SubName: Full=GL24394; GN Name=Dper\GL24394; ORFNames=Dper_GL24394, GL24394; OS Drosophila persimilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7234; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MSH-3 / Tucson 14011-0111.49; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH479179; EDW24891.1; -; Genomic_DNA. DR RefSeq; XP_002013905.1; XM_002013869.1. DR EnsemblMetazoa; FBtr0190009; FBpp0188501; FBgn0161983. DR GeneID; 6587622; -. DR KEGG; dpe:Dper_GL24394; -. DR FlyBase; FBgn0161983; Dper\GL24394. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4G5M5; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. DR SUPFAM; SSF48371; SSF48371; 3. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1390 AA; 159530 MW; 9EB06AF15A195C74 CRC64; MSVLLADIDA TCAALGYSDG QRYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRAKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGPP SDNHGRKVFM ELIDILQGYK AAFAKDKIWT ALFDKLKQAL EIGFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLYREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPTG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI KEEAQVTRRS AFTVRLCLRE YCTEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNARA LFDMLLNNVC YVLEYRETIL HLLMNYNEAH STKVFLRDVV ETANVFIKMM ERFCQDSVVV QDKRRGAGGR RKKQPKAKSK QTAAPQPTED ELSSKWAEMA SEVCTVLFGE LVLPEDERPI PFDAASDKSI DDQREDCMIR INKLLRTEKL EQAIALLRAA REVWPENEVF GAVAAAPKDE LLLLREIFMH NITTVEPQEE DKEDEDEEND DDDDAENEEF EEQNKGLTEK TFKFDDFARR LLHPKIVRAC TLVLTDWAQI PTRALKAAVT VLHRIAYGCS CPGMLFQAKL FRIFQQVLSV ERDVHQEELR RLGIYVVRKF VEVAPTNPKI YAELLFYKGI REANELETGY CDAYESGTKG TWSEEQETEL RFLFEENQRN PETDKDVIDW ILDNLADKTR TRRGVLKKMK EMGLLFKAPT KRSTKSAQSG KNLWQPEEDE MLRSLYDQYR TEPDCLERLV REFGEQRSKQ QIIKRMLQIH LIADKSEILP AKSSKGRGKG KSKRQQEANS DSGSGSGSEA DEYMEEPMFE DAGTRKPQNK SRSRQVVRTP LDVGTVQALI AQVDTEKYQP AFEWLTECLN DASDDTDEPA EDDDGVPLLP LQQSQKDAME DGNFQKVLVA LGMQPPIAGM ENYWRVPTYL NAADLKLRAK IVSGEEVEIE PENIREEDVD EEDDEEDYLD KRSRQRQQAQ AENITAQQQS RLDSLMFSKS DDDDQAEQRA ALKRKGNGKQ AKRQRKGKAK AMETKESDDE EEKEKETEQP SRASTDDLFE QLKAKRATKI KLGDMVLNES TKAVGDEDGD GDDDAFNFNS EDYRARLLEL EDEDEEDEAE EKNKENNTTK SSSLSLQRAR RVNVIDSDSD NDDAGGASPA DKTNKRPRSD DGQESDEAAE EGDDDANFLA RKKPAKVDTG SGEPAKRRRV AIIDDDDDEF // ID B4G9F8_DROPE Unreviewed; 1340 AA. AC B4G9F8; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 25. DE SubName: Full=GL19475; GN Name=Dper\GL19475; ORFNames=Dper_GL19475, GL19475; OS Drosophila persimilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7234; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MSH-3 / Tucson 14011-0111.49; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH479180; EDW28988.1; -; Genomic_DNA. DR RefSeq; XP_002014992.1; XM_002014956.1. DR EnsemblMetazoa; FBtr0185090; FBpp0183582; FBgn0157074. DR GeneID; 6588719; -. DR KEGG; dpe:Dper_GL19475; -. DR FlyBase; FBgn0157074; Dper\GL19475. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4G9F8; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1340 AA; 151004 MW; 6E0350D54A15A0E7 CRC64; MDWLLTAPQL HSAFASLGSL EGDTYVVSPN ALSILEEINH KLTYEDQTLR TFRRAICFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAK STKSVVEYMK HILESDPKLS PQKCDQINNC LLLLRNILHI PETHGICVMP MMQSNNLHGI TMQNTILWNL FIQSIDKLLI YLMTCPQRSF WGVTMVQLIA LIYKDQHVST LQKLLDLWFE ASLSESSEDN ESNTTPPKQG SGESSPMLTS DPTGSDSSDN GSQGRGMSIS MSLNMSMSMS MNVSMSSLCG KKETPEERQL ALWEGTEATL QEVSRKGQEY QDAIDATHKR MGSAGMDDDE DYHELIEQYH AVQVTPARRQ SAHLTSMPLR STRAMRLYVA AIKLSQKSPH AGKLQLTKGK CCPQKRECSS TQSELSDCGY ATQVENQESV STSSNDDDMP QGKPINMKGL VQHIPTDDDI ANLLKEFTVD FLLKGYNYLV EDLHAQLLTN TLPIDTSHFF WLVTYFLKFA AQLELDMEHI DTILTYDVLS YLTYEGVMQC EQLEQCARQR DSDLKPHLRR MHLLVTAIRE FLQAIEAYNK VSHLSDDDRD HLRQLHIQIA DTSDLHCLFV LLLRRFNPTI YSKQYLQDLI VTNHILLLIL DNRPQLDGKK TENLTQHVAQ FATLEVMHYY GILLEDFTSN GEFVNDCIFT MMHHVGGDLE QIGVLFQPII LKTYSRIWEM EFTLCDDWSD LIEYVINKFM NTPPKTPMTI PTTSLTAMTK EHNLEHAKCS WNADEMDTLY WYFVQSRSTN DVVGKIVRLF SNNGNKEKSR ISIIQQLLQQ DIITLLEYDD LMRYEDAEYQ RTLLNTPTSV TTESGIEMKD GGFGRPSGDI QILLDLIIKD QKGQHLEWVQ KVLLECCYIK LNLKSGRQMP HIMEPVAYHY ILLHKSIPVV QWNNEQSAAM MYQPFVLLLH KLGIQLPVDA GSIFARIPDY WSPAQMYGMA KKLGPVNKQA LKFDATELEE AAAAAAASAA ASAASMRSHH NRGPRNSLSS QSSLEVDMGD TDGELPLIPE VDAAVEKAHA MDCSSSSNNE FFAVPKVKTA NTMMRYTPDT TPPVPNWLQL VMRSKRNPRP APIGEINDCI SSTAIVKGDD ECKSSRSLCS TMYQTGQTMA MTPMPPMNAI HPLNTMSIMP RLHSIMGPHN ENSSSSGCGG TVYSQAMGVL MTTSAVGAIM RGDVEEDAAI KSSFEKLEVK GTHFARASHL EEEYSAMVAD AFKNEIFNDN GSVASDLTRM YVSDEDEKHE FRVYPAHTII ESESKISWKG EKKGRKGKGQ // ID B4HGA8_DROSE Unreviewed; 1383 AA. AC B4HGA8; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 27. DE SubName: Full=GM24087; GN Name=Dsec\GM24087; ORFNames=Dsec_GM24087, GM24087; OS Drosophila sechellia (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7238; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Rob3c / Tucson 14021-0248.25; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH480815; EDW42356.1; -; Genomic_DNA. DR RefSeq; XP_002031370.1; XM_002031334.1. DR EnsemblMetazoa; FBtr0207072; FBpp0205564; FBgn0178951. DR GeneID; 6606569; -. DR KEGG; dse:Dsec_GM24087; -. DR FlyBase; FBgn0178951; Dsec\GM24087. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4HGA8; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1383 AA; 159381 MW; EAB3185DFF3FFB53 CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIEILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGGGA SRKKKQAATK SKPPAAPQPT EEELSSKWAE LATEVCSLLS TELEMPEDEQ PMPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MYNITTVESE DKENEKEQNQ DEYEDEDDDL DNEEYEEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL KAAVTILHRI AYGCKCAGML FQAKLFRIFQ QVFSVERDVH QEELRRLAIF VVRKFVEVAP TNPKIYAELL FYKGIREANE LETGYCDAYE AGTKGAWTEE QESELRFLFE ENQRNPETDK DVIDWILDNL VDKTRNRRTV LKKLKELGLM FKAPTKRSTK SAQSGKNVWQ PEEDDELRSL YDQHRIEPDC LERLVHEFAE RRSKQQIIKR MLQIHLIADK SEILPAKKGR GKDKPKKEAE MEGDGDEFDF AEEPMLEEQG YKKLKSKPKK AKKRQMVRTP LDVGTIRALI GQVDSEKYQS AIEWLQECLQ DASEDTEEAV EDDDGVPLLP LMQDQKNAME DGDFQKVLVA LGMQPPITGM EAYWRIPIYL NSADLLLRSK ILAGEEVNAE PEDEAADDEE CEEAEESEEE DFLEKHSRQR QENIATQQQR KLDSLMFNQS DDETEQRAPP KAKDKPKASE KKAKRKVKDK AKESKDSNDD GTDKAELEKP NTDDLFNQLR AKRATKIKLS DMALNESTNA AQEEDDDAFN FNSEDYRARL LELEDEEQNS KDADENGGDK ENITNKSLQR ARRVNVIDSD SDNDDDGALP ADKTNKRPRS DDDGDAGHMD ATAEEDSDEE ANFLARKKPA KVDGEPAKRR RLAIIVDDDE DDF // ID B4I2Z6_DROSE Unreviewed; 1364 AA. AC B4I2Z6; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 24. DE SubName: Full=GM18146; GN Name=Dsec\GM18146; ORFNames=Dsec_GM18146, GM18146; OS Drosophila sechellia (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7238; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Rob3c / Tucson 14021-0248.25; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH480820; EDW54141.1; -; Genomic_DNA. DR RefSeq; XP_002037723.1; XM_002037687.1. DR EnsemblMetazoa; FBtr0201131; FBpp0199623; FBgn0173053. DR GeneID; 6613246; -. DR KEGG; dse:Dsec_GM18146; -. DR FlyBase; FBgn0173053; Dsec\GM18146. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4I2Z6; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1364 AA; 152797 MW; AFBDF1B8D2FBB9A3 CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAR STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAHCVMP MMQSMPHGIS MQNTILWNLF IQSIDKLLLY LMTCPQRAFW GVTMVQLIAL IYKDQHGSGD SSPMLTSDPT SDSSDNGSNG RGMGGGMREG TAATLQEVSR KGQEYQNAMA RVPADKPDGS EEASDMTGND SEQPGSPEQS QPAGESMDDG DYEDQRHSQL NEHGEEDDDE DEVEEEEYLQ LGPASEPLNL TQQPADKVNN TTSPTSSPPQ GCLGTEPFKP PPPLPVRAST SAHAQLQKFN ESSYASHVSA VKLGQKSPHA GQLQLTKGKC CPQKRECPSS QSELSDCGYG TQVENQESIS TSSNDDDGPQ GKPQHQKPPC NTKPRNKPRT IMSPMDKKEL RRKKLVKRSK SSLINMKGLV QHTPTDDDIS NLLKEFTVDF LLKGYSYLVE ELHMQLLSNA KVPIDTSHFF WLVTYFLKFA AQLELDMEHI DTILTYDVLS YLTYEGVSLC EQLELNARQE GSDLKPYLRR MHLVVTAIRE FLQAIDTYNK VTHLNEDDKA HLRQLQLQIS EMSDLRCLFV LLLRRFNPSI HSKQYLQDLV VTNHILLLIL DSSAKLGGCQ TIRLSEHITQ FATLEVMHYY GILLEDFNNN GEFVNDCIFT MMHHIGGDLG QIGVLFQPII LKTYSRIWEA DYELCDDWSD LIEYVIHKFM NTPPKSPLTI PTTSLTEMTK EHNQEHTVCS WSQEEMDTLY WYYVQSKKNN DIVGKIVKLF SNNGNKLKTR ISIIQQLLQQ DIITLLEYDD LMKFEDAEYQ RTLLTTPTSA TTESGIEIKE CAYGKPSDDV QILLDLIIKE NKAQHLLWLQ RILIECCFVK LTLRSGLKVP EGDHIMEPVA YHCICKQKSI PVVQWNNEQS TTMLYQPFCA AAPQTRAFSC RRTRARSLPE FPDYWTPETM YGLGPRSWDR WTNFDTSELE DATASSPSRY HHTGPRNSLS SVSSLDVDLG EPEELALIPE VDAAVEKAHA MASTPSPSEI FAVPKTKHCN SIIRYTPDPT PPVPNWLQLV MRSKCNQRTG PAGDPSDCVG SSSTTVDDEG LGKSISAPTS QAASTSMSTV NPTTTLSLNM LNTFMGSHNE NSSSSGCGGT VSSLSMVALM STGAAGGGGN TSGLDMDVDA SMKSSFERLE VNGSHFSRAN NLDQEYSAMV ASVYEKEKEL NSDNVSLASD LTRMYVSDED DRLERTEIRV PHYH // ID B4JEV1_DROGR Unreviewed; 938 AA. AC B4JEV1; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 29. DE SubName: Full=GH18380; GN Name=Dgri\GH18380; ORFNames=Dgri_GH18380, GH18380; OS Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila. OX NCBI_TaxID=7222; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15287-2541.00; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH916369; EDV93232.1; -; Genomic_DNA. DR RefSeq; XP_001990170.1; XM_001990134.1. DR STRING; 7222.FBpp0152286; -. DR EnsemblMetazoa; FBtr0153794; FBpp0152286; FBgn0125848. DR GeneID; 6563724; -. DR KEGG; dgr:Dgri_GH18380; -. DR FlyBase; FBgn0125848; Dgri\GH18380. DR eggNOG; NOG328380; -. DR InParanoid; B4JEV1; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4JEV1; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 938 AA; 108889 MW; 1373A49F83E86656 CRC64; MSVLLADIDA TCAALGVSDG KRYQAEPDAA EGLKHLIWIL RRDVDNHEYR RHLGRSKVLQ TDLVYMLPDY VEHEELADLL IRLLVILTNP TLLLYRDGPP NDNHGRKVFL ELIDILQGYK AAFAKDKIWT ALFEKLKQSL ETAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFIVSSPDE EQFHLHGLEI ICLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRREN ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DIICHQPLQR VSAIDFDREK QAQKRSHRHI KEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIQ CDKKQARLWA KRLHVALLTF RELLQSLLGL QKLKDDDNAR GLFDMLLNNV CYVLEYRETI LHLLMNYNEG HSTKVFLRDV VETANVFIKM MERFCQDAVL VQDKRRGGGG KRKKQHPATK SKQPPAAAQP SEEELSRKWA EMASEVSLLL ATDLELPEHE RPLPFDAALE KSIEDQREDC MMRLNKLLRS GKLEQAIVLL RSAREVWPEE DVFGSYTAAP EDEWLLLREI FMHNITTEEA NVDGNQDVDA DEDEEELDEP DNGLTEKTFK FDDFARRLLH PKIVHACTLV LTDWTRIPTT ALKAAVTILH RIAYGCSCPG MLYQAKLFRI FQQVFAVERD AHQEELRRLG IYVLRKFVEV APTNPKIYAE LLFYKGIREA NELETGYCDA YETGTKGAWT EEQEVELRFL FEENQRNPET DKDVIDWILE NLVDKTRTRR GILKKLKEMS LLFKAPTKRS TKAALGGKNL WPPEEDEELS SLYDQHRLEP DCLERIVREF EARRNKQQII KRMLQLHL // ID B4JQG0_DROGR Unreviewed; 1351 AA. AC B4JQG0; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 26. DE SubName: Full=GH13197; GN Name=Dgri\GH13197; ORFNames=Dgri_GH13197, GH13197; OS Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila. OX NCBI_TaxID=7222; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15287-2541.00; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH916372; EDV99140.1; -; Genomic_DNA. DR RefSeq; XP_001993215.1; XM_001993179.1. DR STRING; 7222.FBpp0147103; -. DR EnsemblMetazoa; FBtr0148611; FBpp0147103; FBgn0120674. DR GeneID; 6566725; -. DR KEGG; dgr:Dgri_GH13197; -. DR FlyBase; FBgn0120674; Dgri\GH13197. DR eggNOG; NOG257888; -. DR InParanoid; B4JQG0; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4JQG0; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1351 AA; 151559 MW; CCCFC184F9017B38 CRC64; MDYLLVTPQL HSVFSSLGSF EGDTYVVSPN AFAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTEVGRH TIFELNKLLY NCKEAFTDPK VTKSVVEYIK HILESESKLS PQKCDRINNC LLLLRNILHI PETMLQSNSG HQVSMQNTIL WNLFIQSIDK LMLYLMTCPQ RSNWGVTMVQ LIALIYKDQH GSGDSSPMLT SDPTSDSSDN GMSGKKEGCE ERRQALRDGT EATLHEVSRK GHEYQNAMNR VSAKKEKKAN TESASDMTNL SVQQQLIKKE EEEEDMNDNS YEERVRNYEQ KQTARNSEPL DFTQPADNVN STTAQPYATP IVLDNPSASS PSTTGVSQCY EPFKPPAPLH LRRTVLEDML SDSYTSHPNI SAVKLGQKSP HGGQLHLTKG KCSPQKRECP SSQSELSDCG YATQVENQES ISTSSNDDDG PQGKPAHQKP PCNMKPRNKT RNLMDAPMDK KELRRKKLVK RSKSSLINMK GLVQHTPTDD DISNLLKEFT VDFLLKGYNF LVEELHSQLL CNAVPIDTSH FFWLVTYFLK FAAQLELDME HIDTILTYNV ISYLTYEGVN LCEQLELNAR QEGSDLRPYL RRMHLVVTAI REFLQAIETY SKVTHLSEDD RERLRHLQLQ IASTTDLRCL FVLLLRRFNP SIHSKQYLQD LVVTNHILLL ILDSAGKLEG GHTIGIANHI SQFATLEVMH YYGILLEDFN NNGEFVNDCI FTMMHHIGGD LGHTGVLFQP IILKTYSRIW EADYGLCDDW SDLIEYVIHK FMNTPPKSPL TLPTTSLTEM TKEHNQEHTL CTWSQEEMDT LYWYYVQSKK NIDIVGKIVK LFSNNGNKIK TRIAIIQQLL QQDIITLLEY DDLMRFEDAE YQRTLLTTPS SASTESGIDI KDSAYGKPSD DVQILRDLII KENKSHHLVW LQKLLLECCY IKLMMKCTTT FPAVDPVMEP VAYHCILKHK SVPVVQWNNE QSTTMLYQPF VLLLHKLGIQ LPADAGSIFA RIPDFWTPET LYGLAKKLGS LDKLTLKFDP SELDDTASLS GSSGYHNTGP RNSLRSMSSL EADIAGSDEL PVIPEVDSAV EKAAAASSIA SCTDIFAVPK AKHCNSIIRY TPDPTPPVPN WLQVVMRSKC NQRPGSAADI SDCVSSTTLT ADDEGMGKSN CSASQASQTL LCVANPTSTL ACLTKMGNSS FSASHNENSN SSGCGGTVSS QSLAGALMCT SVADANLDAV MKSSFERLDV TGAHFARASN LDQEYSAMVA SVYGNEMANS DNVSVASDLT RMYVSDEDEN LEFREREPLY H // ID B4K1K6_DROGR Unreviewed; 362 AA. AC B4K1K6; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 03-SEP-2014, entry version 24. DE SubName: Full=GH23554; GN Name=Dgri\GH23554; ORFNames=Dgri_GH23554, GH23554; OS Drosophila grimshawi (Fruit fly) (Idiomyia grimshawi). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Hawaiian Drosophila. OX NCBI_TaxID=7222; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15287-2541.00; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH917446; EDW04939.1; -; Genomic_DNA. DR RefSeq; XP_001997160.1; XM_001997124.1. DR STRING; 7222.FBpp0157460; -. DR EnsemblMetazoa; FBtr0158968; FBpp0157460; FBgn0131011. DR GeneID; 6570950; -. DR KEGG; dgr:Dgri_GH23554; -. DR FlyBase; FBgn0131011; Dgri\GH23554. DR eggNOG; NOG257888; -. DR InParanoid; B4K1K6; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 362 AA; 41901 MW; A0109B909B7D84AE CRC64; MDYLLVTPQL HSVFSSLGSF EGDTYVVSPN AFAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTEVGRH TIFELNKLLY NCKEAFTDPK VTKSVVEYIK HILESESKLS PQKCDRINNC LLLLRNILHI PETMLQSNSG HQVSMQNTIL WNLFIQSIDK LMLYLMTCPQ RSNWGVTMVQ LIALIYKDQH IPTLEVMHYY GILLEDFNNN GEFVNDCIFT MMHHIGGDLG HTGVLFQPII LKTYSRIWEA DYGLCDVSLT LTKHARITFL TFTFYFLLQD WSDLIEYVIH KFMNTPPKSP LTLPTTSLTE MTKEHNQEHT LW // ID B4K8G7_DROMO Unreviewed; 1412 AA. AC B4K8G7; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 23. DE SubName: Full=GI23372; GN Name=Dmoj\GI23372; ORFNames=Dmoj_GI23372, GI23372; OS Drosophila mojavensis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7230; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15081-1352.22; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH933806; EDW14366.1; -; Genomic_DNA. DR RefSeq; XP_001998905.1; XM_001998869.1. DR EnsemblMetazoa; FBtr0174097; FBpp0172589; FBgn0146098. DR GeneID; 6572799; -. DR KEGG; dmo:Dmoj_GI23372; -. DR FlyBase; FBgn0146098; Dmoj\GI23372. DR InParanoid; B4K8G7; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4K8G7; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1412 AA; 161447 MW; 3FCD59AD8B810079 CRC64; MSVLLADIDA TCAALGVSDG KRYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRAKVLQ TDLVYMLPDY VHDAELSDLL IRLLVILTNP TLLLYRDGPP SDNHGRKVFL ELIDILQGYK VAFAKDKIWA ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFIISSPDE EQFHLHGLEI ICLLYREQSA TSREGERQRR SLSDKRTDKL EMIAARRREH ARGQARPPFG RHSRFGGTYV IRNMKSVSDR DIICHQPLQG VSAMDFDRDK QGQKGSHRHI KEEGQVTGRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIL CDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDDNAR GLFDMLLNNV CYVLEYRETI LHLLMNYNEA HSTKVFLRDV VDTANVFIKM MERFCQDAVV VQDKRRGAAG KRKKKKKQQA SNKPSKSSQQ PTEEELATKW AEMASEVSLL LATELQLPEE QQPLPFDATL EKSIDDQRED CMMRINKLLR NAKLESAIAL LRAAREVWPE EDVFGSYTAA PEDELLLLRE IFMHNITTVE AADEPNENEN EDNASEEDVE NEEFGEPDNG LTEKTFKFED FARRLLHPKI VRACTIVLTD WAQIPTRALK AAVTILHRIA YGCSCPGMLY QAKLFRIFQQ VFSVERDAHQ EELRRLGIYV VRKFVEVAPT NPKIYAELLF YKTVREANEL ETGYCDAYEA GTKGAWSEEQ EMELRFLFEE NQRNPETDKD VIDWILDNLV DKTRTRRGVL KKLKEMGLLF KAPTKRSTKA ALGGKNLWQP EEDEELSDLY DQHRLEPDCL QRIVDAFGER RNKQQILKRM VQLHLIADKS EVLPAKASKG KRKQAKMQED SNSDEESEQE QEQEDYMEEP TFGEPLSRPK AKSKSKPRVR VRTPLDVGTV RALIAQVDAE ALDWLRECLE DASEDAEEAG EDDDGVPLLP LLDSQKAAME QADFQKVLVA LGMQPPIVGM ESYWRIPSYL NAADLKLRAK IVAGEEVEPD NDSEEESQPA GDSEQEDEEE EDYLDKRSRQ RQQAAAQNIS VQQQQQRKLD SLMFNKSDDE AEQRKPPARA KGKRSKKGKA KAELQQKDSS DEEEQRQELA GKPNTDDLFE QLKAKRATKI KLKDMVLDEA SQPATDGQEP GEQDDALEFN SEGFRARLLE LEEEEQEQPA ESEHDKENAT LQANNTIKAN SSSASASVAS SSLQRTRRAN VIDSDSDNDD AGAMPAYKTN KRPRSDNEQE DGQQRDEPDT DDEDINFLAR KKPASTEPAK RRRLAIIDDD DDDGGVDGNN DF // ID B4KK95_DROMO Unreviewed; 1348 AA. AC B4KK95; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 24. DE SubName: Full=GI17777; GN Name=Dmoj\GI17777; ORFNames=Dmoj_GI17777, GI17777; OS Drosophila mojavensis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7230; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15081-1352.22; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH933807; EDW12626.1; -; Genomic_DNA. DR RefSeq; XP_002003184.1; XM_002003148.1. DR EnsemblMetazoa; FBtr0168502; FBpp0166994; FBgn0140518. DR GeneID; 6577215; -. DR KEGG; dmo:Dmoj_GI17777; -. DR FlyBase; FBgn0140518; Dmoj\GI17777. DR InParanoid; B4KK95; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4KK95; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1348 AA; 150879 MW; 83943E20DF45D409 CRC64; MDWLLATPQL HSVFSSLGSL VGDTYVVSPN ALAILKEINY KLTYEDQTLR TFRRAIGFGQ NVRSNLIPLL ENAKDDEVLE SVIRILVSLT VPVEWLFSVD IMNRTEVGRH TIFELNKLLY SCKEAFTDPK STKSVVEYMK HILESDTKLS PHKCDQINNC LLLLRNILHI PETHAHFLMP VMQSSVERQV SMQNIILWNL FIQSIDKLLL YLMTCPQRAL WGVTMVQLIA MIYKDQHGSG DSSPMLTSDP TSDSSDNGSN GGGSSNGKKE GSDERRQALR EGTEATLQEV SRKGHEYQNA MARATADEPN ASEEASDIFG APCSSQQQHL STEEAMDDYE DQAQEYVQEA AIVSSEPLNL TQPADNVNST TNAVYASTTA TETRTTSSLC GATSLCYEPF KPPAPLPSRR STLSEMLSDS YTSHSHVSAV KLGQKSSHAG QLQLTKGKCC PQKRECPSSQ SELSDCGYAT QVENQESIST SSNDDDGPQG KPQHQKPPCN TKPRNKQRTL MSPQDKKELR RKKLVKRSKS SLINMKGLVQ HMPTNYDISN LLKEFTVDFL LKGYNYLVEE LHKQLLTSTV LIDTSHFFWL VTFFLKLAAQ LELDMEHIDT ILTYDVLSYL TYEGVSLCEQ LELNAQQEGS DLQPYLRRMH LVVTAIREFL QTIETYNKVT HLSEDDRLRL HQLQLQIGAT SDLRCLFVLL LRRFNPRIHS KQYLQDLVVT NHILMLILDS AAKLEGGQTI GLSEHIAQFA TLEVMHYYGI LLEDFDNNGE FVNDCIFTMM HHIGGDLGQI GMLFQPIILK TYSRIWEADY ELCDDWSDLI EHVIHKFMNT PPKSPLTIPT TSLTEMTKEH NQEHTVCTWS QEEMDTLYWY YVQSKKNNDI VGKIVKLFSN NGNKLKTRIS IIQQLLQQDI ITLLEYDDLM KFEDAEYQRT LLTTPTSATT ESGIELKESA AGKPSDDVQI LLDLIIKEHK SHHLVWLQKL LLECCYIKLM LKSGSSLAEA DPIMEPVAYH YIYKQKSIPV VQWNNEQSTT MLYQPFVLLL HKLGIQLPAD AGSIFARIPD YWTPETMFGL AKKLGPLDKL TLKFDPSELE ETPSSSASSR YHHTGARNSL SSIGSLDADY AEPEELALIP EVDAAVEKAA AAGAAISVSD IFAVPKAKHC NSIIRYTPDP TPPVPNWLQL VMRSKCNQRP GPTADTGDCA IVGEDEGMGK SNASTQQAQC TANPSSTLAK LNKLSNCTFM LPPNENSSSS GCGATVSSQS AGVMLGNSSP DANADAVMKS SFERLEVTGT HFARPNNLDQ EYSAMVASVY DNEIANSDNV SVASDLTRMY VSDEDERHEF RVPVPHYH // ID B4LRU8_DROVI Unreviewed; 1311 AA. AC B4LRU8; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 25. DE SubName: Full=Tim; GN Name=tim; Synonyms=Dvir\tim; ORFNames=Dvir_GJ17601, GJ17601; OS Drosophila virilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7244; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15010-1051.87; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH940649; EDW64700.1; -; Genomic_DNA. DR RefSeq; XP_002052545.1; XM_002052509.1. DR EnsemblMetazoa; FBtr0233526; FBpp0232018; FBgn0022834. DR GeneID; 6628265; -. DR KEGG; dvi:Dvir_GJ17601; -. DR FlyBase; FBgn0022834; Dvir\tim. DR KO; K12074; -. DR OMA; LHIPETH; -. DR PhylomeDB; B4LRU8; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1311 AA; 147331 MW; AEC56B176384E07B CRC64; MDWLLATPQL QSVFSSLGSL VGGTYVVSPN ALAILEEINH KLTYEDQTLR TFRRAIGFGQ NVRVDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD LMYRTEVGRH TIFELNKLLY NSKEAFTDPK STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAHFLMP RLQPGSGHQV SMQNTILWNL FIQSIDKLLL YLMTCPQRSL WGVTMVQLIA LIYKDQHASG DSSPMLTSDP TSDSSDNGSG GKKESCEERR QALREGTDAT LHEVSRKGHE YQNAMASSNA ANYILEGPCS AQQPWSDCEM QEYKQMTAVI SEPLNLSQPA DNVNYTTNAN YARTTSADIL TKTTSLKHEG FKPPAPRRNT LSAILSDNYA PLSFISAVKL GQKSPHAGQL QLIKGKCCPQ KRECPSSQSE HSDCGYGTQM ENPESISTSS NDDDGPQGKP QHQKPPCSSK HRSKQRIFAV PQDTKDLRRK KLVKRSKSSL INMKGLVLHT PNDDDISNLL KEFTVDFLLK GYNYLVEELH SQLLSNAKMP IDTSHFFWLV TFFLKFAAQL ELDMEHIDTI LTFDVLSFLT YEGVSLCEQL ELNARQEGAD LRPYLRRMHL VVTAIREFLQ AIEAYNKVTH LSEDDRYRLR QLQLQISATT DLRCLFVLLL RRFNPSIHSK QYLQDLVVTN HILLLILDNA AKLEGGQTIG LSEHISQFAT LEVMHYYGIL LEDFSNNGEY VNDCIFTMMH HIGGDLDQVG VLYQPIILKA YSRIWEADYD ICDDWSDLIE YVIHKFLNTP PKSPMAIPTA SLTELTKEHN QEHTACPWSQ EDMDSLCWYF VQSKRQNDVI GNIAKLFSNN GNKIKTRISI IQQLLQQDII TLLEYDDLMK FEDAEYQRTL LATPTSLTTD SGIELKESAY GKPSDDVQVL LDLIRKENKS QHLVWLQKLL LECCYVKMMI KCGSCQTDVE PIMEPVVYHC MFKQKPIPVV QWNNEQSSTM LYQPFMLLLH KLGIQLPADA GLIFARIPDF WTPETMYGLA KKLGPLDKLT LKFDPRDLED APPSRHHTGA RNSLSSISSL EADFGDSEGL ALIPEVDPAV EKAAAAASAI PNNEIFALPR VKHCNSIIRY TPDPTPPVPS WLQLVMRSKC SKRRSPATDA SDCTSTSTMI ADDEIKSYAS MAQASHTKLN AGYPTSTLVC MNKLSNCSFA APPNENSSSS GCGGTASSMS MPNMPDGNSD ALMKTSFERL AVTGARYLRP SNTDQDYSAL VASVYENEFA NSDNVSVASD LTRMYVSDED EKHELQLQQV E // ID B4M6L1_DROVI Unreviewed; 1435 AA. AC B4M6L1; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 28. DE SubName: Full=GJ10366; GN Name=Dvir\GJ10366; ORFNames=Dvir_GJ10366, GJ10366; OS Drosophila virilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7244; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 15010-1051.87; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH940652; EDW59287.1; -; Genomic_DNA. DR RefSeq; XP_002056175.1; XM_002056139.1. DR STRING; 7244.FBpp0224783; -. DR EnsemblMetazoa; FBtr0226291; FBpp0224783; FBgn0197650. DR GeneID; 6632474; -. DR KEGG; dvi:Dvir_GJ10366; -. DR FlyBase; FBgn0197650; Dvir\GJ10366. DR eggNOG; NOG297449; -. DR InParanoid; B4M6L1; -. DR KO; K03155; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4M6L1; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1435 AA; 165275 MW; 9270CE3F2561E31A CRC64; MSVLLADIDA TCAALGVSDG KRYQAEPHAA EGLKHLIWIL RRDLDNHEYR RHLGHAKVLQ TDLVYMLPDY VQHEELADLL IRLLVILTNP TLLLYREGPP KDNHGRKVFL ELIDILQGYK VAFAKDKIWT ALFDKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFIVSSPDE EQFHLHGLEI ICLLYREQSA ESLADASLQR SLSEKQRDQQ ELLAARRREM ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DIICHQPLQR VSAMDFDREK QAQKRSHRHI KEEGQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIQ CDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDVNAR GLFDMLLNNV CYVLEYRETI LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDAVV VQDKRRAGGG KRNAGNSKKK QQQASKSKHS QPTEEELSSK WAEMASEVSL LLATDLQLPK EQHPLPFDAT LEKSIEDQRE DCMMRINKLL RNGKLEPAIA LLRAAREVWP EEDVFGSYTA APEDELLLLR EIYMHNITTV DATDEPNDDE NENEANASDE EIENEEFGEP DNGLTEKTFK FEDFARRLLH PKIVRACTLV LTDWTQIPTR ALKAAVTILH RIAYGCSCPG MLYQAKLFRI FQQVFSVERD AHQEELRRLG IYVVRKFVEV APTNPKIYAE LLFYKGIREA NELETGYCDA YEAGTKGAWS EEQELELRFL FEENQRNPET DKDVIDWILE NLVDKTRTRR GILKKLKELD LVFKAPTKRS TKAALGGKNL WQPEEDEQLS SLYDEHRFVP DCLERIVTAF EERRNKQQII KRMLQLHLIA DKSEILPAKA SKGRRKPTKK QQASDSDERE EQEDYMEEPT FGEPLPKHAF AKSKPRQRVR TPLDVGTVRA LISQVDAEKY AEALDWVREC LEDASEDTEE AAEDDDDGVP LLPLLDIQKD AMELADFQKV LLALGMQPPV AGMENYWRIP SYLNAADLKL RAKIVVGAEL EQDNDSDEEL LPGGDDDEEN DEDYIDKHSR RQQRAAAQNI TAQQQRKLDS LMYSKSDDDA EQREPPMKAK GKRPRKAKAK QQQKESVDEQ EVNEIARKLA RKKRQPDVSS EESEPEQEQQ QPGKPNTDDL FEQLKAKRAT KIKLKDMVLD ESTKATTEEE QEQDDDALNF NSEGYKARLL ELEEEEEQQH EEEQEQVLPV ETEHNKENAT LQANNTIKTP VSANSLSGAL QRTRRANVID SDSDNDDAGA KPAYKANKRP RSDNDEQDGQ QRDEPDTDTE DEDINFLARK KPASTEPAKR RRLAVIEDDD DDDDF // ID B4MV73_DROWI Unreviewed; 1425 AA. AC B4MV73; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 26. DE SubName: Full=GK14675; GN Name=Dwil\GK14675; ORFNames=Dwil_GK14675, GK14675; OS Drosophila willistoni (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7260; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14030-0811.24; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH963857; EDW76418.1; -; Genomic_DNA. DR RefSeq; XP_002065432.1; XM_002065396.1. DR STRING; 7260.FBpp0243818; -. DR EnsemblMetazoa; FBtr0245326; FBpp0243818; FBgn0216681. DR GeneID; 6642215; -. DR KEGG; dwi:Dwil_GK14675; -. DR FlyBase; FBgn0216681; Dwil\GK14675. DR eggNOG; NOG257888; -. DR InParanoid; B4MV73; -. DR KO; K12074; -. DR OMA; LHIPETH; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4MV73; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1425 AA; 159801 MW; 0A2BAF582B36ECD7 CRC64; MDWLLTTPQL HSAFASLGSL EGDTYVVSPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTEVGRH TIFELNKLLF TSKEAFTDPK STKSVVEYMK HILESETKLS PQKCDQINNC LLLLRNILHI PETHGHCVMA MMQSSGAQMS MQNTILWNLF IQSIDKLMLY LMTCPQRAIW GVTMVQLIAL IYKDQHVSTL QKLLNLWFEA SLSESSEDNE SNTSPPKQGS GDSSPMLTSD PTSDSSDNGS NGGGNTKKDG HGRQVVSRKG QEYQNSMARV SLDKLDSSEA ASDIMEQSPR HQGMDESDSY GDERQERVDD DDDNEEEEGP NDDEDNERKQ QQLEEEQEAL QKQQPADLVN NTTTITTTTT ITTTSSKINL VLSDFKPPPI PQSVRPSTSA QALQQQQQLQ QQLQQEQEQK PLLTESYQSS HISAVKLGQK SPHSGQLQLT KGKCCPQKRE CPSSQSELSD CGYGTQGEIQ ESISTSSNDD DIPQGKPQHQ KPPCNTKPRN KLRSVMSPQD TKELRRKKLV KRSKSSLINM KGLVLHTPTD DDISNLLKEF TVDFLLKGYN YLVEELHIQL LSNAKIPIDT SHFFWLVTYF LKFAAQLELD MEHIDTILTY DVLSYLTYEG VTLCEQLELN ARQEGSDVKP YLRRMHLVVT AIREFLQAIE TYKKVTHLSE DDRMHLRQLQ LQISEMSDLR CLFVLLLRRF NPSIHSKQYL QDLVVTNHIL LIILDSAAKL EGGEAIKLSE HVSQFATLEV MHYYGILLED FNNNGEFVND CIFTMMHHIA GDLGQIGVLF QPIILKTYSR IWEADYELCD DWSDLIEYVI HKFMNTPPKS PLTIPTTSLT EMTKEHNQEH TVSTWSQEEM DTLYWYYVQS KKNNDIVGKI VKLFSNNGNK LKTRITIIQQ LLQQDIITLL EYDDLMKFED AEYQRTLLTT PTSVTTESGI ELKECAYGKP SDDIQILLDL IIKEHKSQHL VWLQKLLLEC CYIKLMLKSG NKSSGDSMVP IMEPVAYHCI CKQKSIPVVQ WNNEQSTTML YQPFVLLLHK LGIQLPADAG SIFARIPDYW TPETMYGLAK KLGPMDKLHI KFDASELEDA TSLASPSARY HHLPRNSLSS ISSLEVDLLD SGEELALIPE VDAATEKAHA QASPVSSPCE IFAIPKAKHC NSIIRYTPDP TPPVPNWLQL VMRSKCNQRS ASAAALETSL GDCVSSTNMT LVDEGVGRSS TTSVSQSMAS TSNSATLGCL AMINPIMGGH NENSSSSGCG GTVSSLSISG LMSTSIATTA GGVAPVVAAA VTSSVSKSLD VDDDAAMKSS FERLEVNNGH FMRTNNLDQE YSAMVASVYE NEIVNNDNVS VASDLTRMYV SDEDEKHEFR VPHYH // ID B4NG61_DROWI Unreviewed; 1605 AA. AC B4NG61; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 41. DE SubName: Full=GK22409; GN Name=Dwil\GK22409; ORFNames=Dwil_GK22409, GK22409; OS Drosophila willistoni (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7260; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tucson 14030-0811.24; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH964251; EDW83278.1; -; Genomic_DNA. DR RefSeq; XP_002072292.1; XM_002072256.1. DR ProteinModelPortal; B4NG61; -. DR STRING; 7260.FBpp0251552; -. DR EnsemblMetazoa; FBtr0253060; FBpp0251552; FBgn0224388. DR GeneID; 6649629; -. DR KEGG; dwi:Dwil_GK22409; -. DR FlyBase; FBgn0224388; Dwil\GK22409. DR eggNOG; NOG328380; -. DR InParanoid; B4NG61; -. DR KO; K03155; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4NG61; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR Gene3D; 3.30.40.10; -; 1. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR017907; Znf_RING_CS. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00184; RING; 1. DR SMART; SM00717; SANT; 1. DR PROSITE; PS00518; ZF_RING_1; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 4: Predicted; KW Complete proteome; Metal-binding; Zinc; Zinc-finger. SQ SEQUENCE 1605 AA; 184841 MW; 9967DA48BC162A8A CRC64; MSVLLADIDA TCAALGYSDG QRYQAEPDAV EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLIYMLADY AQHEELSDLL IRLLVILTNP TLLLYREGPP NDNHGRKVFM ELIDILQGYK AAFARDKIWT ALFEKLKQAL EVDGNMERVY GQGDGDGEGD SNTSSDESSV VDEGPTYYSC SVCLRTARNP QVNFCGHHFC ARCIANWIYT RGSRANCPYC LSRIGENTLI SIRYSESLWY SNRLPNSRSL EEHRRMLLQG AEYIKEGPYL PSAGMFNSGY VEYPPQPLMR LKPLAPQLLR QEKSLPIRRQ FVDHTWGQRI MMLMIMIFLL GMCHIGTLRS FAVRSEEQNL LIERLLVLVR NVLQVPANPE AECRADNDAS LHDQVIWALH QTGMLDLVLF VISSPDESQF HLHGLEIICL LYREQSAESL ADASMQRSVS EKQRDQQELL AARRRERSKR QARPPPGRHS RFGGTYVIRN MKSVSDRDVI CHQPLERVSA IDFDREKQQQ KRSHRHIKEE AQVTRRSAFT VRLCLREYCI EVLRSAYNTL VRQVRRVLER NAGSTSHDDS YLLWAIRFFM EFNRLSGLQL QLVSESLSVQ CFHWVLTRMQ HDMDMIVTDK KQARLWAKRL HVALLTFREL LQSLLGLQKL KDDNNARALF DMLLNNVCYV LEYRETILHL LMNYNEAHST KVFLRDVVET ANVFIKMMER FCQDSVLVQE KRRGGGKRAG NGKKKQQAAK SNKRSTVQPT EEELSNKWAE LATEVCALLS TDLELPEHEQ PIPFDAAAEK SIDDQREDCM IRINKLLRME KLEEAIALLR AAREVWPEND VFGAISAAPE DELLLLREIF MHNITTVETQ EQEDNEAENE DGDDDDEMEN EEFGETQDNG MTEKTFKFDD FARRLLHPKI VRACTVVLTD WTQIPTKALK AAVTILHRIA YGCSCPGMLY QAKLFRIFQQ VFSVERDAHQ EELRRLAIYV VRKFVEVAPT NPKIYAELLF YKSIREANEL ETGYCDAYEA GTKGTWTEAQ ETELRFLFEE NQRNPETDKD VIDWILDNLV DKTRTRRGVL KKLKDLGLQF KGPTKRSTKA TMAGKNLWQP EEDEELTSLY EQHRTQEDCL QRLIHEFEDR RTKQEIIKRM LQLHLIADKS EIMPAKGRGK AKSKKQKQQA NNESESDDDN EDMEEPMFSN AGSRKPVKAK PKSRKVIRTP LDAGTVRALI GQVDEEKYQT AIEWLKECLD DVSEDTDEPA EDDDGVPLLP LLEAQKEAMD DGNFQKVLVA LGMQPPIVGM ENYWRIPTYL NAADLKLRAQ ILAGEEIEIT ETETHDDVEE EEVEEGEEED YLDKRSRQRQ QAEADNIAAQ QQRKLDSLMF SKSDDEIEQR APPKGVGKPK RQRKNKAKKS ISPEDDEDED ENENDTDKKK NQPTKPNTDD LFEQLKAKRA TKMKLTDMVL NESTKATIQN QKEEEEAEEE PEQDDAFNFN SEDYRARLLE LEEEEEQQEH NKENNTIKSS AKSLQRTRRV NVIDSDSDND DGDDDAAGGA QPSPVDKANK RPRSDNDQTD DKEDSSEDAN FLARKKPAKV NAANGEPPKR RRVAVIDDDD DDNDF // ID B4NXX7_DROYA Unreviewed; 1376 AA. AC B4NXX7; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 09-JUL-2014, entry version 30. DE SubName: Full=Tim; GN Name=tim; Synonyms=Dyak\tim; ORFNames=Dyak_GE14857, GE14857; OS Drosophila yakuba (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7245; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tai18E2 / Tucson 14021-0261.01; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=17550304; DOI=10.1371/journal.pbio.0050152; RA Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., RA Roote J., Ashburner M., Bergman C.M.; RT "Principles of genome evolution in the Drosophila melanogaster species RT group."; RL PLoS Biol. 5:E152-E152(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000157; EDW87548.1; -; Genomic_DNA. DR RefSeq; XP_002087836.1; XM_002087800.1. DR STRING; 7245.FBpp0259867; -. DR EnsemblMetazoa; FBtr0261375; FBpp0259867; FBgn0020061. DR GeneID; 6526733; -. DR KEGG; dya:Dyak_GE14857; -. DR FlyBase; FBgn0020061; Dyak\tim. DR eggNOG; NOG257888; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4NXX7; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1376 AA; 153279 MW; AC47212E9D715358 CRC64; MDWLLATPQL HSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAK STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAQCVMP MMQSMPHGIS MQNTILWNLF IQSIDKLLLY LMTCPQRAFW GVTMVQLIAL IYKDQHGSGD SSPMLTSDPT SDSSDNGSNG RGMGGGMREG TAATLQEVSR KGQEYQNAMA RVPADKADGS EEASDVTGND SEQPGSPEQS QPTGESMDDG DYEDQRRSQL NENGERDKDE DEVEEEEYLQ LAPPSEPLNL TQQPADKVNN TTTPTSSPTQ GCLGNEPFKP PPPLPVRAST SAQAQMQQFN DSSYASHVTA VKLGQKSPHA GQLQLTKGKC CPQKRECPSS QSELSDCGYG TQVENQESIS TSSNDDDGPQ GKPQHQKPPC NTKPRNKPRT TMSPMDKKEL RRKKLVKRSK SSLINMKGLV QHTPTDDDIS NLLKEFTVDF LLKGYSYLVE ELHMQLLSNA KVPIDTSHFF WLVTYFLKFA AQLELDMEHI DTILTYDVLS YLTYEGVSLC EQLELNARQE GSDLKPYLRR MHLVVTAIRE FLQAIDTYSK VTHLNEDDKA HLRQLQLQIS EMSDLRCLFV LLLRRFNPSI HSKQYLQDLV VTNHILLLIL DSSAKLGGGQ SIRLSEHITQ FATLEVMHYY GILLEDFNNN GEFVNDCIFT MMHHIGGDLG QIGVLFQPII LKTYSRIWEA DYELCDDWSD LIEYVIHKFM NTPPKSPLTI PTTSLTEMTK THNQEHTVCS WSQEEMDTLY WYYVQSKKNN DVVGKIVKLF TNNGNKLKTR ISIIQQLLQQ DIITLLEYDD LMKFEDAEYQ RTLLTTPTSG TTESGIEIKE CAYGKPSDDV QILLDLIIKE NKAQHLLWLQ RILIECCFVK LTLRSGLKLS EGEHIMEPVA YHCICKQKSI PVVQWNNEQS TTMLYQPFVL LLHKLGIQLP ADAGSIFARI PDYWTPETMY GLAKKLGPLD KLNLKFDASE LEDATTTSPS RYHHTGPRNS LSSVSSLDVD LGEPEELALI PEVDAAVERA HAMASTPSPS EIFAVPKTKH CNSIIRYTPD PTPPVPNWLQ LVMRSKCNQR TGPAGDPSDC VGSSSTTVED EGLGKSISAA TSQAASTSMS TVNPTTTLSL NMLNTFMGSQ NENSSSSGCG GTVSSLSMVA LMSTGAAGGG GGGGGGGGGV VVTSGLDMDA DASMKTSFER LEGNGSHFSR ANNLDQEYSA MVASVYEREK ELNSDNVSLA SDLTRMYVSD EDDRLERTEF RVPHYH // ID B4PPX0_DROYA Unreviewed; 1578 AA. AC B4PPX0; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 09-JUL-2014, entry version 41. DE SubName: Full=GE26249; GN Name=Dyak\GE26249; ORFNames=Dyak_GE26249, GE26249; OS Drosophila yakuba (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7245; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tai18E2 / Tucson 14021-0261.01; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=17550304; DOI=10.1371/journal.pbio.0050152; RA Ranz J.M., Maurin D., Chan Y.S., von Grotthuss M., Hillier L.W., RA Roote J., Ashburner M., Bergman C.M.; RT "Principles of genome evolution in the Drosophila melanogaster species RT group."; RL PLoS Biol. 5:E152-E152(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000160; EDW97197.1; -; Genomic_DNA. DR RefSeq; XP_002097485.1; XM_002097449.1. DR ProteinModelPortal; B4PPX0; -. DR STRING; 7245.FBpp0271259; -. DR EnsemblMetazoa; FBtr0272767; FBpp0271259; FBgn0243280. DR GeneID; 6536916; -. DR KEGG; dya:Dyak_GE26249; -. DR FlyBase; FBgn0243280; Dyak\GE26249. DR eggNOG; NOG297449; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4PPX0; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro. DR Gene3D; 3.30.40.10; -; 1. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR InterPro; IPR018957; Znf_C3HC4_RING-type. DR InterPro; IPR001841; Znf_RING. DR InterPro; IPR013083; Znf_RING/FYVE/PHD. DR InterPro; IPR017907; Znf_RING_CS. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. DR Pfam; PF00097; zf-C3HC4; 1. DR SMART; SM00184; RING; 1. DR SMART; SM00717; SANT; 1. DR PROSITE; PS00518; ZF_RING_1; 1. DR PROSITE; PS50089; ZF_RING_2; 1. PE 4: Predicted; KW Complete proteome; Metal-binding; Zinc; Zinc-finger. SQ SEQUENCE 1578 AA; 181645 MW; 35FC15259743B0D7 CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHQEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIDKRNPKSF NGGGGDSGDG EEPWMDKFTY YVCPVCVQTA ESPRVSFCGH HFCAKCISNW IKTQEYSANC PYCQSLIGEN TLITIRHKHQ ANTMESSSSC RSLDEQRRQM RMSSDYISEL IILPEAGMFT RGQIGYPADP MPRIKPLPPQ MLQQWSSIPI ERKFVSPTLH QRFITLAIFL FMFAMYQHMA RAFAIRSEEQ NLLIERILVL VRNVLQVPAN PEAECRADND ASLHDQVIWA LHQTGMLDLV LFVISSPDEE QFHLHGLEIV CLLFREQSAE SLADASLQRS LSEKQRDQQE LLAARRRERA RRQARPPPGR HSRFGGTYVI RNMKSVSDRD VICHQALERV SSIDFDREKQ QQKRSHRHIQ EEAQVTRRSA FTVRLCLREY CIEVLRSAYN TLVRQVRRVL ERNAGSSSHD DSYLLWAIRF FMEFNRLSGL QLQLVSESLS VQCFHWVLTR MQHDMDMIVS DKKQARLWAK RLHVALLTFR ELLQSLLALQ KLKDDNNARA LFDMLLNNVC YVLEYRETVL HLLMNYNEAH STKVFLRDVV ETANVFIKMM ERFCQDSVVV QDKKRSGGGS RKKKQAATKS KPPAAPQPTE EDLSSKWAEL ATEVCSLLSS ELEMPEDEQP IPFDAASEKS IDDQREDCMI RINKLLRSEK LDQAIALLRA AREVWPENEV FGAISAAPED ELLLLREIFM YNITTVESED KENEKEQKQD EDDDDDLDNE EYGEQDNGLT EKTFKFDDFA RRLLNPKIVR ACTLVLSDWA DIPTRSLKAA VTILHRIAYG CKCSGMLFQA KLFRIFQQVL SVERDVHQEE LRRLAIFVVR KFVEVAPTNP KIYAELLFYK GIREANELES GYCDAYEAGT KGAWSEEQES ELRFLFEENQ RNPETDKDVI DWILDNLVDK TRNRRTVLKK LKELGLLFKA PTKRSTKSAQ SGKNVWQPEE DDELRSLYDQ HRIEPDCLER IVNEFGERRT KQQIIKRMLQ IHLIADKSEI LPAKKGRGKG KSKKEQPEME GEGDEYDFAE EPMFEEQGYK KPKAKPKKAQ KRHVVRTPLH VGTIKALIGQ VDSEKYQSAI EWLQECLQDA SEDTEEATED DDGVPLLPLM QDQKDAMEDA DFQKVLVSLG MQPPISGMEA YWRIPIYLNS ADLQLRSKIL AGEEVDVEPE DEAADEDEEG EQDEESEEEE DFLEKHSRQR QENIATQQQR KLDSLMFNQS DDETEQRAPP KPKDKPKASE KKAKRKVKEK AKESKDSDDD RADKAELEKP NTDDLFNQLR AKRATKIKLS DMALNESTNA AQEADDDAFN FNSEDYRARL LELEDEEQNA EAADENGGDK ENITNKSLQR ARRVNVIDSD SDNDDDGALP ADKANKRPRS DDDRDDEDED AGHMDANAEE DSDEEANFLA RKKPAKVDGE PAKRRRLAII DDDDEDDF // ID B4Q9L3_DROSI Unreviewed; 1382 AA. AC B4Q9L3; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 23. DE SubName: Full=Tim; GN Name=tim; Synonyms=Dsim\tim; ORFNames=Dsim_GD22753, GD22753; OS Drosophila simulans (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7240; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Mixed; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000361; EDX03624.1; -; Genomic_DNA. DR RefSeq; XP_002078039.1; XM_002078003.1. DR EnsemblMetazoa; FBtr0222663; FBpp0221155; FBgn0020076. DR GeneID; 6730875; -. DR KEGG; dsi:Dsim_GD22753; -. DR FlyBase; FBgn0020076; Dsim\tim. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; B4Q9L3; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1382 AA; 154416 MW; FC9F6090D6C22CF4 CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAR STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAHCVMP MMQSMPHGIS MQNTILWNLF IQSIDKLLLY LMTCPQRAFW GVTMVQLIAL IYKDQHVSTL QKLLSLWFEA SLSESSEDNE SNTSPPKQGS GDSSPMLTSD PTSDSSDNGS NGRGMGGGMR EGTAATLQEV SRKGQEYQNA MARVPADKPD GSEEASDMTG NDSEQPGSPE QSQPAGESMD DGDYEDQRHS QLNEHGEEDE DEDEVEEEEY LQLGPASEPL NLTQQPADKV NNTTSPTSSP PQGCLGTEPF KPPPPLPVRA STSAHAQMQK FNESSYASHV SAVKLGQKSP HAGQLQLTKG KCCPQKRECP SSQSELSDCG YGTQVENQES ISTSSNDDDG PQGKPQHQKP PCNTKPRNKP RTIMSPMDKK ELRRKKLVKR SKSSLINMKG LVQHTPTDDD ISNLLKEFTV DFLLKGYSYL VEELHMQLLS NAKVPIDTSH FFWLVTYFLK FAAQLELDME HIDTILTYDV LSYLTYEGVS LCEQLELNAR QEGSDLKPYL RRMHLVVTAI REFLQAIDTY NKLQISEMSD LRSFFVLLLR RFNPSIHSKQ YLQDLVVTNH ILLLILDSSA KLGGCQTIRL SEHITQFATL EVMHYYGILL EDFNNNGEFV NDCIFTMMHH IGGDLGQIGV LFQPIILKTY SRIWEADYEL CDDWSDLIEY VIHKFMNTPP KSPLTIPTTS LTEMTKEHNQ EHTVCSWSQE EMDTLYWYYV QSKKNNDIVG KIVKLFSNNG NKLKTRISII QQLLQQDIIT LLEYDDLMKF EDAEYQRTLL TTPTSATTES GIEIKECAYG KPSDDVQILL DLIIKENKAQ HLLWLQRILI ECCFVKLTLR SGLKVPEGDH IMEPVAYHCI CKQKSIPVVQ WNNEQSTTML YQPFVLLLHK LGIQLPADAG SIFARIPDYW TPETMYGLAK KLGPLDKLNL KFDTSELEDA TASSPSRYHH TGPRNSLSSV SSLDVDLGEP EELALIPEVD AAVEKAHAMA STPSPSEMFA VPKTKHCNSI IRYTPDPTPP VPNWLQLVMR SKCNQRTGPA GDPSDCVGSS STTVDDEGLG KSISAATSQA ASTSMSTVNP TTTLSLNMLN TFMGSHNENS SSSGCGGTVS SLSMVALMST GAVGGGGNTS GLDMDVDASM KSSFERLEVN GSHFSRANNL DQEYSAMVAS VYEKEKELNS DNVSLASDLT RMYVSDEDDR LERTEIRVPH YH // ID B4R1V9_DROSI Unreviewed; 1333 AA. AC B4R1V9; DT 23-SEP-2008, integrated into UniProtKB/TrEMBL. DT 23-SEP-2008, sequence version 1. DT 11-JUN-2014, entry version 27. DE SubName: Full=GD18885; GN Name=Dsim\GD18885; ORFNames=Dsim_GD18885, GD18885; OS Drosophila simulans (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7240; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Mixed; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000364; EDX13111.1; -; Genomic_DNA. DR RefSeq; XP_002103608.1; XM_002103572.1. DR EnsemblMetazoa; FBtr0218795; FBpp0217287; FBgn0190396. DR GeneID; 6728259; -. DR KEGG; dsi:Dsim_GD18885; -. DR FlyBase; FBgn0190396; Dsim\GD18885. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; B4R1V9; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1333 AA; 153779 MW; 9E11A47157295D42 CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTFNRLSGL QLQLVSESLS VQCFHWVLTR MQHDMDMIVS DKKQARLWAK RLHVALLTFR ELLQSLLALQ KLKDDNNARA LFDMLLNNVC YVLEYRETVL HLLMNYNEAH STKVFLRDVV ETANVFIKMM ERFCQDSVVV QDKKRGGGAS RKKKQAATKS KPPAAPQPTE EELSSKWAEL ATEVCSLLST ELEMPEDEQP MPFDAASEKS IDDQREDCMI HINKLLRSNK LDQAIGLLRA AREVWPENEV FGAISAAPED ELLLLREIFM YNITTVESED KENEKDQQQD EYEDEDDDLD NEEYEEQDNG LTEKTFKFDD FARRLLNPKI VRACTLVLSD WADIPTRSLK AAVTILHRIA YGCKCAGMLF QAKLFRIFQQ VFSVERDVHQ EELRRLAIFV VRKFVEVAPT NPKIYAELLF YKGIREANEL ETGYCDAYEA GTKGAWTEEQ ESELRFLFEE NQRNPETDKD VIDWILDNLV DKTRNRRTVL KKLKELGLMF KAPTKRSTKS AQSGKNVWQP EEDDELRSLY DQHRIEPDCL ERLVHEFAER RSKQQIIKRM LQIHLIADKS EILPAKKGRG KDKPKKEAEM EGEGDEFDFA EEPMLEEQGY KKLKSKPKKA KKRQMVRTPL DVGTIRALIG QVDSEKYQSA IEWLQECLQD ASEDTEEAVE DDDGVPLLPL MQDQKNAMED GDSQKVLVAL GMQPPITGME AYWRIPIYLN SADLLLRSKI RQKKRLKLSR KTRLQTMRRA KMPEESEEEE DFLEKHSRQR QENIATQQQR KLDSLMFNQS DDETEQRALP KSKDKPKASE KKAKRKVKDK AKESKDSNDD GTDKAELEKP NTDDLFNQLR AKRATKIKLS DMALNESTNA AQEEDDDAFN FNSEDYRARL LELEDEEQNS KDADENGGDK ENITNKSLQR ARRVNVIDSD SDNDDDGALP ADKTNKRPRS DDDGDAGHMD ATAEEDSDEE ANFLARKKPA KVDGEPAKRR RLAIIDDDDE DDF // ID B5DVE2_DROPS Unreviewed; 139 AA. AC B5DVE2; DT 14-OCT-2008, integrated into UniProtKB/TrEMBL. DT 14-OCT-2008, sequence version 1. DT 03-SEP-2014, entry version 16. DE SubName: Full=GA23143; GN Name=Dpse\GA23143; ORFNames=Dpse_GA23143, GA23143; OS Drosophila pseudoobscura pseudoobscura (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=46245; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25 / Tucson 14011-0121.94; RX PubMed=15632085; DOI=10.1101/gr.3059305; RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., RA Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., RA van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E., RA Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., RA Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., RA Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., RA Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., RA Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., RA Weinstock G.M., Gibbs R.A.; RT "Comparative genome sequencing of Drosophila pseudoobscura: RT chromosomal, gene, and cis-element evolution."; RL Genome Res. 15:1-18(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH676349; EDY71893.1; -; Genomic_DNA. DR RefSeq; XP_002136857.1; XM_002136821.1. DR STRING; 7237.FBpp0282236; -. DR EnsemblMetazoa; FBtr0275279; FBpp0273717; FBgn0244545. DR GeneID; 6903614; -. DR KEGG; dpo:Dpse_GA23143; -. DR FlyBase; FBgn0244545; Dpse\GA23143. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 139 AA; 16310 MW; 9AA1302FF29BD826 CRC64; MLDLVLFVIS SPDEEQFHLH GLEIVCLLYR EQSAESLADA SLQRSLSEKQ RDQQELLAAR RRERARRQAR PPTGRHSRFG GTYVIRNMKS VSDRDVICHQ ALERVSSIDF DREKQQQKRS HRHIKEEAQV TRRSAFTVR // ID B5VQE1_YEAS6 Unreviewed; 1238 AA. AC B5VQE1; DT 25-NOV-2008, integrated into UniProtKB/TrEMBL. DT 25-NOV-2008, sequence version 1. DT 13-NOV-2013, entry version 11. DE SubName: Full=YNL273Wp-like protein; GN ORFNames=AWRI1631_140560; OS Saccharomyces cerevisiae (strain AWRI1631) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=545124; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AWRI1631; RX PubMed=18778279; DOI=10.1111/j.1567-1364.2008.00434.x; RA Borneman A.R., Forgan A.H., Pretorius I.S., Chambers P.J.; RT "Comparative genome analysis of a Saccharomyces cerevisiae wine RT strain."; RL FEMS Yeast Res. 8:1185-1195(2008). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABSV01001948; EDZ69856.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141110 MW; AB59A264384EDF3F CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEGDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFSPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGVL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID B5Y4M8_PHATC Unreviewed; 944 AA. AC B5Y4M8; DT 25-NOV-2008, integrated into UniProtKB/TrEMBL. DT 25-NOV-2008, sequence version 1. DT 14-MAY-2014, entry version 23. DE SubName: Full=Timeless; GN Name=TIM_2; ORFNames=PHATR_33206; OS Phaeodactylum tricornutum (strain CCAP 1055/1). OC Eukaryota; Stramenopiles; Bacillariophyta; Bacillariophyceae; OC Bacillariophycidae; Naviculales; Phaeodactylaceae; Phaeodactylum. OX NCBI_TaxID=556484; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CCAP 1055/1; RX PubMed=18923393; DOI=10.1038/nature07410; RA Bowler C., Allen A.E., Badger J.H., Grimwood J., Jabbari K., Kuo A., RA Maheswari U., Martens C., Maumus F., Otillar R.P., Rayko E., RA Salamov A., Vandepoele K., Beszteri B., Gruber A., Heijde M., RA Katinka M., Mock T., Valentin K., Verret F., Berges J.A., Brownlee C., RA Cadoret J.P., Chiovitti A., Choi C.J., Coesel S., De Martino A., RA Detter J.C., Durkin C., Falciatore A., Fournet J., Haruta M., RA Huysman M.J., Jenkins B.D., Jiroutova K., Jorgensen R.E., Joubert Y., RA Kaplan A., Kroger N., Kroth P.G., La Roche J., Lindquist E., RA Lommer M., Martin-Jezequel V., Lopez P.J., Lucas S., Mangogna M., RA McGinnis K., Medlin L.K., Montsant A., Oudot-Le Secq M.P., Napoli C., RA Obornik M., Parker M.S., Petit J.L., Porcel B.M., Poulsen N., RA Robison M., Rychlewski L., Rynearson T.A., Schmutz J., Shapiro H., RA Siaut M., Stanley M., Sussman M.R., Taylor A.R., Vardi A., RA von Dassow P., Vyverman W., Willis A., Wyrwicz L.S., Rokhsar D.S., RA Weissenbach J., Armbrust E.V., Green B.R., Van de Peer Y., RA Grigoriev I.V.; RT "The Phaeodactylum genome reveals the evolutionary history of diatom RT genomes."; RL Nature 456:239-244(2008). RN [2] RP GENOME REANNOTATION. RC STRAIN=CCAP 1055/1; RG Diatom Consortium; RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., RA Detter J.C., Lindquist E., Shapiro H., Lucas S., Glavina del Rio T., RA Pitluck S., Rokhsar D., Bowler C.; RL Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP001142; ACI65508.1; -; Genomic_DNA. DR RefSeq; XP_002186038.1; XM_002186002.1. DR STRING; 2850.JGI33206; -. DR EnsemblProtists; Phatr33206; Phatr33206; Phatr33206. DR GeneID; 7204296; -. DR KEGG; pti:PHATR_33206; -. DR HOGENOM; HOG000075081; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 944 AA; 105998 MW; B4A98A72AE4DD4FB CRC64; MTSTIGVTDR RALAAAQSSP PPRSSAASRR VTPPRDALSV EPSVVDELLL VCGVIGTTVS DTDTPDRIVP VADCLNWLQD LQRALRRDDD QYRPISLLMA QWKIVPQKLL PLVDSCRYDT DLVLTVAKIL VILTKPLAES TERAGKLPIE TKTKTTEAVI REQIRLRENA VQQAEARMEY KRAICHYHHG HTHDSNPTKS GGGILSIFVS LLAEPLSKSG TARTEADHLK IELVLHLFRN LLSAEPLLHS SAAAVAQAQT LHDDCVVLLD QELVLEILLV LGADIEQREN LQYNLLLMEL VHHLLRHYDP AVVARAVPSP TGAAAALPPK PRPGLLSQSL QREKQKFHAP IMSRHAHFGG TLVVKQAHNP TQQQYVSTAA LGPGHRSAPL ASKRKTKKSE PFIGSKSHPS HHTRTAATLT PSRQKAVAVL QAFCQRWVQD CYGPVTKSLK HEFRRDSVRL EESDRITFFR MVWFFARWWR LSPAAVRSRQ VQQDDTVSNQ SAVGQLIFTM DVFAFNLVLN ATDTFQQHKK YARLALTVAL LGEMMHLLTA MYSSQESTEQ IMAMGLMDRL FYGSEPLDRL PKLLSSWQPG SSTRDYLCDL VEVVHVQLKL LDTHAQACRN VDTSQAKHDT VAKMKLAAAD FDTTHYLTRR IISNHVVYMY TQLLTQYDVN AAHVNHRIVA FLLRLTKLQI AGTVEPEDVV LPAQKLLTAP NVTLQPMLYN FQVLRVFQTI LNDKSIRRDK DYVTLLAFAA GIVHDFAQAA ERNPVLFVEA LFKHPVPHRF CEYSANLYVT EELRMIAERE LLLEEQRKFE EQVAAVRDDD DSEDELEFED LEVESEVATK TVSLGSKRKV LYDSDSDEGE TDPAPSLPAG TTSSREVETG DSEDSSDDDE KIRESLEQEH SSILGDFAKT GVVDPDHSSD EEEFDRWVEE PPLKKKRSVD EDDQ // ID B6H3J8_PENCW Unreviewed; 1127 AA. AC B6H3J8; DT 16-DEC-2008, integrated into UniProtKB/TrEMBL. DT 16-DEC-2008, sequence version 1. DT 11-DEC-2013, entry version 26. DE SubName: Full=Pc13g06840 protein; GN ORFNames=Pc13g06840, PCH_Pc13g06840; OS Penicillium chrysogenum (strain ATCC 28089 / DSM 1075 / Wisconsin OS 54-1255) (Penicillium notatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium; OC Penicillium chrysogenum complex. OX NCBI_TaxID=500485; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 28089 / DSM 1075 / Wisconsin 54-1255; RX PubMed=18820685; DOI=10.1038/nbt.1498; RA van den Berg M.A., Albang R., Albermann K., Badger J.H., Daran J.-M., RA Driessen A.J.M., Garcia-Estrada C., Fedorova N.D., Harris D.M., RA Heijne W.H.M., Joardar V.S., Kiel J.A.K.W., Kovalchuk A., Martin J.F., RA Nierman W.C., Nijland J.G., Pronk J.T., Roubos J.A., RA van der Klei I.J., van Peij N.N.M.E., Veenhuis M., von Doehren H., RA Wagner C., Wortman J.R., Bovenberg R.A.L.; RT "Genome sequencing and analysis of the filamentous fungus Penicillium RT chrysogenum."; RL Nat. Biotechnol. 26:1161-1168(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AM920428; CAP91753.1; -; Genomic_DNA. DR RefSeq; XP_002559117.1; XM_002559071.1. DR STRING; 500485.B6H3J8; -. DR GeneID; 8305556; -. DR KEGG; pcs:Pc13g06840; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR BioCyc; PCHR:PC13G06840-MONOMER; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1127 AA; 128480 MW; 26991D3A3791A53A CRC64; MDEEVVPLGH DVQVVDPDVR NCVYGLVTAL GGFNGENADQ YVLGDDALAC LRDIKRWLKL YDEKNNRMDV ARCLGEANLI NGDLLPILSL WWASGQNSKH MTRIALACLE LLVPLTWPVE FHSQMTVNHH RHTPYIQQTQ VQYKRGILRS GGLNLLRAVI RISLPSMATP RSERGTRDEG ILKLMLYLLR NIAIISPNTR LAAEGDEEET SRSATINAFH EQDAFALLLT MCSNVGEDFN LQDIPLMETL FHTVKGVNVE KLFMDDEQRT AKRTDELSDL LKKESLVRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QGVLRDDQTT LQKMDESKKW NKPRPRRRQE DVVQNNNFNM PAHLNSEATK NLRTFVEEFL DSGFNPLFTH VRKAIEREAE RVVPINHRQF FYTVGWFLEA ERVRRARQLR HRTAQNGGRT KDIEPDSYGL VAGVLNQETF ISLNRAMQSS LDNKEWEDLN AQMRCFTQIL LTVQEMALSP LEEDQEIAEN IQNRIFYEET THDRILTIVR GYKDQGFGYL DACTELAHVF LRMLERYSKD NVDMQIRSRR KARKRQKKAA QVAEQEGEDV DEERDSEDED MEEAAQVTKE RSFDFKRFSA KFCNQSCVDT FIAFTGFYRE LNSEQLKRAH RYFYRIAFKQ EMTVLLFRVD IISLFYRMIK GPGSMDPNKS VFKEWEELVR QVIRRLVKKL DQRPALVTEL LFSKINSTVY YLEYGHEKQT ISTYKRPPPE LVITSTDATT KEAKLHIVIG ALVLDGRADL VTWIKDVLSS AASEREDWET QEEVRRAENP ETISVPNPMI TSLKSDDLRE TISEILKALQ TPFSGDGNDD PRKHLQPKNK GSVRGNMTQG TLNVNFGSES EGEDIPDGPL FPANPRSKSS ALDDLKKKRK KKQATTEREP LDDETLEARR DARLSNALSR QAKIKSDLFI HASDEESDEE ADKEFFRLEE ERRIQQAKEI KKALLTGTVE PSSKGKGKKS AARKRVGDTG TSAAAKSKRR RRDSGSTASG AESDADGDIL MAELDAESSH SQQGISTSHG ARENEDTPLT SGEDDLTFDD DFAFTGDRPS KLQATEPEAV DDDEENEPVA PARRRMRGGF VIESDSE // ID B6K106_SCHJY Unreviewed; 995 AA. AC B6K106; DT 16-DEC-2008, integrated into UniProtKB/TrEMBL. DT 16-DEC-2008, sequence version 1. DT 19-MAR-2014, entry version 12. DE SubName: Full=Replication fork protection complex subunit Swi1; GN ORFNames=SJAG_02724; OS Schizosaccharomyces japonicus (strain yFS275 / FY16936) (Fission OS yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; OC Schizosaccharomycetes; Schizosaccharomycetales; OC Schizosaccharomycetaceae; Schizosaccharomyces. OX NCBI_TaxID=402676; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=yFS275 / FY16936; RX PubMed=21511999; DOI=10.1126/science.1203357; RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N., RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., RA Guo Y., Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., RA Bayne E.H., Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., RA FitzGerald M.G., French C., Gujja S., Hansen K., Keifenheim D., RA Levin J.Z., Mosher R.A., Mueller C.A., Pfiffner J., Priest M., RA Russ C., Smialowska A., Swoboda P., Sykes S.M., Vaughn M., RA Vengrova S., Yoder R., Zeng Q., Allshire R., Baulcombe D., RA Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J., Levin H., RA Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W., RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.; RT "Comparative functional genomics of the fission yeasts."; RL Science 332:930-936(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; KE651166; EEB07627.1; -; Genomic_DNA. DR RefSeq; XP_002173920.1; XM_002173884.1. DR EnsemblFungi; EEB07627; EEB07627; SJAG_02724. DR GeneID; 7051103; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 995 AA; 115725 MW; 0A4F7385917B75F0 CRC64; MDLFTTVQGT VAAIGSIDYS QKDEPYVLSE DALTCLKDIK RWLRLIDEKY DTFEVRYVLA KLCLVKKDLF SILSSWDGNF RNPKSWRIAL GCLEILVPLT WPLETDENTS RENWEMLPNL KQAQEDYKTL IIDHPKNRVI KSILAVLLRP LSTSYEKRTD RDNGIIRIIT YLFRNLSRID EIKSRSETLL SFSSSHILDF IVTACSSIAE FQELDVVFLE IIYYLIRGIA PKVIFTSEES AKNQLNKLLQ DELRSKRINS KNSTTRHTRF GTMTSIVSSD NRRYTVTGQN MQGTGLEKLD STKKYRRAKR KKNNVDDIDK SVQISADAKT VLRGFVTTFM DSSFNPLFES LLRAMEREEP RFLEIHRLYY FYVQSFFLEC LILKDPVKSG VYSNDYAYGL VASVLDPRAL IMLQRVLREA FELRQWPLFQ AGLLAFTKVI TTIHSMSLSS EKEFQDIADN MLSNLFYEES NLELVVSVLK SYRLQSFGFL NALTEFVTVL LKELELFSSA KQYLYVKRRR KKQNREKSNL DIVEEEKLEI EQADTIEQDR LFSFNAYEAR FCHEACVNTF LTFLYHYREL SPVQILRVIT FFHRIFVRQK CQVLLYRLDI LRLFDRISDD YVGFPRSNPA RQEFEAFYRY YAKKLTDNLM RVPALYTELL FPKISGTMYY LQHGEDPAKD NHVSRRGALY ELVPGLTYEQ QIAVCVAVLI NEQKTELLDE LKTSIGIAMN ERKAWEQRIL ALNTEAPPDD EFRDPLAVPV FYLKGETEAF RNAQLKDEFQ EPIDPRHPED PWFLPSSITY EKLSEYSQLL KRFTEQPPVF EGTTAEALLI KKPRGHVRLP SPDNSEDSDS EDENNEFEPD DPITFANRKQ TLKLKPVKRR REISEEELVK RKEQKENKEK EKKSAIKSSK FVVDSDDDPE ADAAFFAAEE ELRRRNALRG KTNNISTAIT GTDFSLLDSY SLDNASSDEM NDETLGLSRK RSRVSKIIVD ESDEE // ID B6QGJ0_PENMQ Unreviewed; 1172 AA. AC B6QGJ0; DT 16-DEC-2008, integrated into UniProtKB/TrEMBL. DT 16-DEC-2008, sequence version 1. DT 13-NOV-2013, entry version 14. DE SubName: Full=DNA repair protein (Tof1), putative; GN ORFNames=PMAA_085690; OS Penicillium marneffei (strain ATCC 18224 / CBS 334.59 / QM 7333). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces. OX NCBI_TaxID=441960; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 18224 / CBS 334.59 / QM 7333; RA Fedorova N.D., Joardar V.S., Maiti R., Schobel S., Amedeo P., RA Galens K., Inman J.M., White O.R., Whitty B.R., Wortman J.R., RA Nierman W.C.; RT "The genome sequence of Penicillium marneffei strain ATCC 18224."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS995901; EEA24575.1; -; Genomic_DNA. DR RefSeq; XP_002148086.1; XM_002148050.1. DR GeneID; 7025697; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1172 AA; 134363 MW; 7D52A141C80B97DB CRC64; MELDAVAVGR DVQVVDPEVR AHVYSLVTAL GGFNGEDVSK YNLGDDALAC LRDIKKWLKL YDDKTNRLDV ARCLGEANLV NGDLLPILGL WYNSEGYKKK HLTRVALACL ELLVPLTWPV EIHDQMTVNH HRHTPYLQQA QVQYKRGILD QHAGLDTLRA VLQVGLPSLT MPKSERTSRD DGILKLMLYL LRNVTMISAP KGLVTDADED ETSRSVTINA FQQQNVFALL LTMCANINED FNFQDTVLLE TLFHLVKGVN VQKMFMNDNE RQKKRNDELS DLLQKENGIR REYAKNAPTR HGRFGTMIWV KRDDAKVSTV SGQDILKDGQ IAFNKMDQTK KWNRPKHGRR QQPEAASGDI SSTTHLTSVA TKNLRTFVEE FLDTGFNPLF THVRKAIERE ADRVTEINIR QFLYLIAWFL QAERERRKYH KKQNERNKGT SKEIEPDNFS LVASVLNQET FVFLNRAMQY SFDHNDWQDL NANMRCFTQI LLTVQEMSTS PFEEDQEIAE NILNRIFYEE TTHDRIISIV RGYKDQGFGY LDACTELSHV FLRMLENYSK ENVDMVVRSK RRSRAKKSDT AGQDVENEEN DNSEAEDLAD AARVAKERKF DFKRFAARFC SQKSVDTFVQ FTTYYRDLSD EQLKRAHRFF YRVAFKQELS IILYRLDILN LFYRMIKGPG ALDSSKPIFR DWEEFVKHLT KKMTKKLNER PALFTELLFS KINATLFFLE YGYERQTISL SGARPPAELE VHPRVGTSKD EKLNVVVAAL IMDGQADLVK WLSDTLRSAA NERITWEAEE EIRQAESTEG IITLPPAPLI EIKPSDDAIR TAIFRNGRLR LLFTLIGLER LGAEDLMGSS WVVPGSLHLS DLNAVNSVIE KGLENPVTEI DGLDPREQIR RVPTAEPKET HQTTLDVDFG SESEGEDAIP DGPLFPPNIR SKSNALRELV EKRRKRNKPD EDKEPLDDAI LEERRRVREE NARARQAKIK SDLFVHDSDD ESDEEADREF FEREEAVRKA QDKRVREALV NKALEEDASN EQLKKKKTTR RKRRSMDDGQ SDKDTESDGQ KRRRITIGGF EMSDDDEDDD VLMTGTNGDV TSRGASTNQG VDEDDTPPTS TEQEEWDLDK ELEQQKPAAV EALHDSDTEE DGPVAGNRRR ARAGFVIDSD SE // ID B7PRZ4_IXOSC Unreviewed; 797 AA. AC B7PRZ4; DT 10-FEB-2009, integrated into UniProtKB/TrEMBL. DT 10-FEB-2009, sequence version 1. DT 19-MAR-2014, entry version 22. DE SubName: Full=Timeless protein, putative; GN ORFNames=IscW_ISCW007376; OS Ixodes scapularis (Black-legged tick) (Deer tick). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; OC Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes. OX NCBI_TaxID=6945; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Wikel; RG Ixodes scapularis Genome Project Consortium; RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., RA Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., RA Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., RA Meyer J., Hill C.A., Birren B., Nene V., Collins F., RA Alarcon-Chaidez F., Wikel S., Strausberg R.; RT "Annotation of Ixodes scapularis."; RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS775741; EEC09366.1; -; Genomic_DNA. DR RefSeq; XP_002401472.1; XM_002401428.1. DR STRING; 6945.ISCW007376-PA; -. DR EnsemblMetazoa; ISCW007376-RA; ISCW007376-PA; ISCW007376. DR GeneID; 8030487; -. DR KEGG; isc:IscW_ISCW007376; -. DR VectorBase; ISCW007376; Ixodes scapularis. DR CTD; 8030487; -. DR eggNOG; NOG257888; -. DR KO; K12074; -. DR OMA; THNDSES; -. DR OrthoDB; EOG7SXW2F; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 797 AA; 88417 MW; 4883C135D6EBD7ED CRC64; MRVFVLLFGQ DQEPSELTEN DLEGLSNCLV LLRNLLHVPD KSESAKFGIS ENTYDDWLSV HNKLIWNLFV HGLDGVLILM LNSEYKVNWA VVVVQIIALL YKDQDVGSLQ HLISNSTSTS ESSEDDIESN TSKHSMHHTS SNDSVQQQSL NKLVGGTAVN SSGPPSTAGD SGYCQSDFTS CSNNSRMSGR DKGDPTRELS TSSASADNLT SSSNGQSSSS DEDNQVKEHI KDPHHKASAK HRAMHSADSP SGSDSSNEDE LLARSKQRSL VAMSRKSKSQ LKGGKCTPSV CLEAAVSSLE FRSTLRDPVW DRKKTLVLLD VSAHVPSNDD IRDFQIEDGL PTDVLLDRRG GLVWTLVVVE EFEGRTKVNQ DKGASLIDRC HFLWVVGYFT GLATALGLSF HHVKPVLSVE VVGLLVYEAI AVCNELDLDV HNSAESSKLL KKRYHLVVRA FRELIAAIGT YNSRCKGDDM RRICVSLAKL EDLRNIPLLL IRKWAAMPGQ LLVDLIITNH LLLLILEYAQ KTEGGLEIDI LGHLTQFATT EVMEKYGEVL KDFRTNSMLV NDCVFTMMHH VAGDLKRPEA LFHPSILSCF VNILNEGAEI PELYEDLVGY VMNRYLKLAG RNPELYAERM PVVHKGAPAS STQPLVFLLN SSKVKDHAES QEVVNEEISE ITDLVLKLKG LGFESQLQWI QKKFLEVCYV KLKSNRPLVD AEPVALHYTL LGQSVPIVAF SEIQSTALKN LDFFQLLQKL GLHVPKPGQC PYIPCSWEPD KLYATARKLG PLSSRKLAKL CFPAANR // ID B7QB49_IXOSC Unreviewed; 143 AA. AC B7QB49; DT 10-FEB-2009, integrated into UniProtKB/TrEMBL. DT 10-FEB-2009, sequence version 1. DT 19-MAR-2014, entry version 20. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=IscW_ISCW012753; OS Ixodes scapularis (Black-legged tick) (Deer tick). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida; OC Acari; Parasitiformes; Ixodida; Ixodoidea; Ixodidae; Ixodinae; Ixodes. OX NCBI_TaxID=6945; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Wikel; RG Ixodes scapularis Genome Project Consortium; RA Caler E., Hannick L.I., Bidwell S., Joardar V., Thiagarajan M., RA Amedeo P., Galinsky K.J., Schobel S., Inman J., Hostetler J., RA Miller J., Hammond M., Megy K., Lawson D., Kodira C., Sutton G., RA Meyer J., Hill C.A., Birren B., Nene V., Collins F., RA Alarcon-Chaidez F., Wikel S., Strausberg R.; RT "Annotation of Ixodes scapularis."; RL Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS899156; EEC16071.1; -; Genomic_DNA. DR RefSeq; XP_002412775.1; XM_002412730.1. DR STRING; 6945.ISCW012753-PA; -. DR EnsemblMetazoa; ISCW012753-RA; ISCW012753-PA; ISCW012753. DR GeneID; 8038579; -. DR KEGG; isc:IscW_ISCW012753; -. DR VectorBase; ISCW012753; Ixodes scapularis. DR CTD; 8038579; -. DR eggNOG; NOG328380; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 2. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 143 AA; 16256 MW; 6D7397BA4D1C812D CRC64; MSAGRVGKER IRLLVDLTNP AILLYKEEVP IEKFSRNNYL EIISHLQSYK LAFTDSKVWI AITKKLETLL HRVGTVPISV ISKAMHLAHL EDLLLYISSS EDETDYCFHS LEILSLMLRE QSPQVLASAA QARSTSEKEQ DVK // ID B8AZ66_ORYSI Unreviewed; 1254 AA. AC B8AZ66; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 19-MAR-2014, entry version 14. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=OsI_18875; OS Oryza sativa subsp. indica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; OC Ehrhartoideae; Oryzeae; Oryza. OX NCBI_TaxID=39946; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038; RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., RA Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., RA Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., RA Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., RA Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., RA Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., RA Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., RA Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., RA Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., RA Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., RA Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J., RA Samudrala R., Wang J., Wong G.K., Yang H.; RT "The genomes of Oryza sativa: a history of duplications."; RL PLoS Biol. 3:266-281(2005). RN [2] RP NUCLEOTIDE SEQUENCE. RA Wang J., Li R., Fan W., Huang Q., Zhang J., Zhou Y., Hu Y., Zi S., RA Li J., Ni P., Zheng H., Zhang Y., Zhao M., Hao Q., McDermott J., RA Samudrala R., Kristiansen K., Wong G.K.-S.; RT "Improved gene annotation of the rice (Oryza sativa) genomes."; RL Submitted (SEP-2006) to the EMBL/GenBank/DDBJ databases. RN [3] RP NUCLEOTIDE SEQUENCE. RA Wang J., Li R., Fan W., Huang Q., Zhang J., Zhou Y., Hu Y., Zi S., RA Li J., Ni P., Zheng H., Zhang Y., Zhao M., Hao Q., McDermott J., RA Samudrala R., Kristiansen K., Wong G.K.-S.; RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000130; EEC78709.1; -; Genomic_DNA. DR STRING; 39946.BGIOSIBCE017961; -. DR Gramene; B8AZ66; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000084060; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; SQ SEQUENCE 1254 AA; 140884 MW; 7E27F776201AD410 CRC64; MDSAALSLTC AGLGGAEEDD DGAVVGYAKG EHCLDNLKDL QRFLRRDDPQ RREVFKQVCK WKIASRDLVP IIENYQADRN LVITAVKVLV FLTMPVEPSS ENVAQQIEYL WDLKAALTRN VAMAVIVSLL EDPLDHLERA SFTEDDWKLV QLVLTLFRNI LAIQEITLGQ KASGEATQLL CLADSFLELM FQENVMDLIL VLTQHMDEPS GYLQQENLLL LEIFHYLFLG RDPELIARAS TAGSKEHVEG NIDTSVHSLR LMMEEEERKK RMFRQRNSEH HSIGGIFTCT AVDGSKSLCK GNPNSASENS LRKIRNVQRG PQKRIAWDNE LLYTPREGTM EMIRNFLEQF LSGGYNVLMQ SVCDDIVKEH HSIQKSDITT FFKVARFVLA FQHEKASNAQ KSNAAVQLPE ASPSDHLDDN LPFLGDICGP VAATLNEGMF NLVISRWRET YDSLKETHDY KTLSAAGSLM KNMIDMVYLV LKVLPDDSRE SQTARVLLYK LFYDQTEQGL TQFLLNLFRS FDTHKQPKSD LADLLGTIHI MLQLMEKLQA RGALRVAKRT RKGRKKKASK NKIENTNLNA EKMEQSNADS TDGTKSALES LPDLKNVDSV AEPPLREQEK VVSNGMDAPD ELTGTSVNLD STSHCEGEPS CADNGELKGN LIDEEDGTSD SSLDDQPPAT SEVDFNVSRL ISTLANNSVV QNICWLLKHY KSNSFRTNHY IICMLRRFCE DLELAPMLYQ MSLLTTFYDI LADQKSSTSK EYTNIVNFLS KIVRKMLRVM KKQPLLFVDV LFWKTRKECH CIDADACLSD ITKDGTNKGG EIGSSKGWRG SINIADSLGD DEVDLVIPHE PYNADKDDDS SSGEREDVSK RSMGATNKSN RILSFSDSEA DDNDSSIQID KIRNTVSRGS QNSEAPKRQG RSIFSEEQEK LMRDLYEKYK DDRKCTHLIA EALDPSGKIT SVQVSRKLTQ LGLRNAMKRR TKVPEAPLSA QELATQMDQM LGEHNCNPKP ETTRRRRKRL NVSHASYEDN TTDGKSSDEE TLQAIKSRTK NKKVPLVGLL PSISQHQDGL ADPDSDDETI GSMLRSGKKK RLLTPDNAMN IEKHQESPDS TNTSNYSPEI SQKQEALQDT YSGDEIIDSM HRSGKKKRLL KSGFTANTQE HEEPLINIGQ DDETISSKDN LHHGLNSSNN SGGAGETELL DDFIEPELDN VENTEQRIID DINITESGDM ATSFADQKPG LKRRHKLVID DDDD // ID B8CBZ9_THAPS Unreviewed; 1135 AA. AC B8CBZ9; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 03-SEP-2014, entry version 21. DE SubName: Full=Uncharacterized protein; GN ORFNames=THAPSDRAFT_9684; OS Thalassiosira pseudonana (Marine diatom) (Cyclotella nana). OC Eukaryota; Stramenopiles; Bacillariophyta; Coscinodiscophyceae; OC Thalassiosirophycidae; Thalassiosirales; Thalassiosiraceae; OC Thalassiosira. OX NCBI_TaxID=35128; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CCMP1335; RX PubMed=15459382; DOI=10.1126/science.1101156; RA Armbrust E.V., Berges J.A., Bowler C., Green B.R., Martinez D., RA Putnam N.H., Zhou S., Allen A.E., Apt K.E., Bechner M., RA Brzezinski M.A., Chaal B.K., Chiovitti A., Davis A.K., Demarest M.S., RA Detter J.C., Glavina T., Goodstein D., Hadi M.Z., Hellsten U., RA Hildebrand M., Jenkins B.D., Jurka J., Kapitonov V.V., Kroger N., RA Lau W.W., Lane T.W., Larimer F.W., Lippmeier J.C., Lucas S., RA Medina M., Montsant A., Obornik M., Parker M.S., Palenik B., RA Pazour G.J., Richardson P.M., Rynearson T.A., Saito M.A., RA Schwartz D.C., Thamatrakoln K., Valentin K., Vardi A., Wilkerson F.P., RA Rokhsar D.S.; RT "The genome of the diatom Thalassiosira pseudonana: ecology, RT evolution, and metabolism."; RL Science 306:79-86(2004). RN [2] RP GENOME REANNOTATION. RC STRAIN=CCMP1335; RG Diatom Consortium; RA Grigoriev I., Grimwood J., Kuo A., Otillar R.P., Salamov A., RA Detter J.C., Schmutz J., Lindquist E., Shapiro H., Lucas S., RA Glavina del Rio T., Bruce D., Pitluck S., Rokhsar D., Armbrust V.; RL Submitted (SEP-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000649; EED88870.1; -; Genomic_DNA. DR RefSeq; XP_002293861.1; XM_002293825.1. DR STRING; 35128.JGI9684; -. DR EnsemblProtists; Thaps9684; Thaps9684; Thaps9684. DR GeneID; 7451623; -. DR KEGG; tps:THAPSDRAFT_9684; -. DR eggNOG; KOG1974; -. DR HOGENOM; HOG000075081; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1135 AA; 124640 MW; 898693FD4EFC6E50 CRC64; MSAAYTSAAA AAAPHIRPQQ QRSPTSVASP DNNAARTSSK PTSAAAAKAA ASGAALGAAA AASIGRAGGG GGSNVTPPSK QQQTKKKRTN NITAAAARAK HPEMTVDKRI IDELLLVCGV IGSTAASAEG ATAADGSNNA ASKGAPNANN APEFIPVTDC LNWLQDLQRA LRRDHDQFRP IALLLGQWRI VASKLLPLVC SCRYDRGLVL TVCKILVILT KPLSDNTKRA GRLTIDVKSG KVDESVIQEQ ITLRDNAIAQ SELLMEYKKL FVKHHTHHYA FQSSSKASNN NSGDDINNNS GTGLLSIFTS LLAEPLSKTG SSRTSTDHLT IELVLHLIRN LLTISPINTF GSTEKSQYAS QLHRELVILL EKEMVLSVLV CVGQEVEKRE NSGYNLLLME IMSCLLRGMD PSDVALSVNE SSIQPISKAP APVIGKGKNK GKPIRTITTT KASTALTIGA NSLRVHLQCE RQKLQLSAQS RHSHFGGTLM ISKPGGKQSY VSATDYLAQK SGGTGGHGVK GSAIGQPVRR KNKKAEVFVG SGKSSALNAR PGASAAFSRE TAGPIAKRAK LALNSFCEKF MGQCYGPVMK SLKNEFRRDS NRLEDGDRTM FFRIVWFFHQ WWRVRKQNGG FKDDTKAVTV EGGEDVAGST SSMAQNLIFT MDVFMFNLVL NSTDEFFEHK KPAELAQTVS LYTEMIHMLH AMYDSEDSTE RMMALGLMDR IYYAAEPLDR LPKLLSRWTP GMFSREYLCD LVECSHVTWK LLDGNAERCL QSLGPDELER KRPKDAVERM NLTASEFDKD AYFMRKFVSN HIVFMHTQLL SQYAVNAAHI NRHIAAYFIR LCKFSIKQGD GDLDYDDVLG KNELASKQAT LEPMLYNIGL FTVMEAILND QGIRDKEDFS ALLMFASSFM KRFARASEAN PMLFVEALFK HPIPHRFCEF TTNMYVNEEL RMIAVRDLLL EDQKRYEQQS DEDGEDRNNG KDGVVAGNDG PGGYASEDEE EVEFNGDDLD EGEFVPGKKR RKRSTKRGSK RAAVSALMRE EEEQPGDDGN GEEAEFGGDN EQSETAEETM GRTSLTKAEA GDQSNVAEAN AAPPKSSGKK RIRKSSVFEE SDDEDFDTVP AKSMKRAIFE DDEDD // ID B8MDV6_TALSN Unreviewed; 1165 AA. AC B8MDV6; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 13-NOV-2013, entry version 14. DE SubName: Full=DNA repair protein (Tof1), putative; GN ORFNames=TSTA_120790; OS Talaromyces stipitatus (strain ATCC 10500 / CBS 375.48 / QM 6759 / OS NRRL 1006) (Penicillium stipitatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Trichocomaceae; Talaromyces. OX NCBI_TaxID=441959; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 10500 / CBS 375.48 / QM 6759 / NRRL 1006; RA Fedorova N.D., Joardar V.S., Maiti R., Schobel S., Amedeo P., RA Galens K., Inman J.M., Galinsky K.J., White O.R., Whitty B.R., RA Wortman J.R., Nierman W.C.; RT "Genome sequence of Talaromyces stipitatus strain ATCC 10500."; RL Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EQ962655; EED18335.1; -; Genomic_DNA. DR RefSeq; XP_002482327.1; XM_002482282.1. DR GeneID; 8100063; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1165 AA; 133275 MW; D41F222D93359466 CRC64; MELDAVAVGR DVQVVDPEVR AHVYSLVTAL GGFNGEDVSK YNLGDDALAC LRDIKKWLRL YDDKTNRLDV ARCLAEANIV NGDLLPILNL WYNGEGQKKK HLTRVALACL ELLVPLTWPV EIHGQMTINH HRHTPYLQQA QVQYKRGILD QNTGLQTLRA VIQIGLPSFT MPKSERTSRD DGILKLMLYL LRNVAMISAP KGLVTDADEE ETSRSTTINA FQQQNVFALI LTMSANISED FNFQDVVLLE ILFHLVKGVD VQKLFMNDTE RKAKHNDELS DLLKKESGVK REYAKNAPTR HGRFGTMIWV KRDDAKVSTV SGQDILKDGQ IAFNKMDQTK KWNRPKHGRR QQPEAASGDF TLSTHLTSTA TKNLRTFVEE FLDTGFNPLF THVRKAIERE ADRVTDINTR QFLYVVAWFL QAERERRSYQ RKQNERNKGT SKEIEPDNFS LVASVLNQET FVFLNRAMQY SFDNHEWQDL NANMRCFTQI LLTIQEMAAS TFEEDQEIAE NTLNRIFYEE TTHDRIISIV RGYKDQGFAY LDACTELSHV FLRMLENYSK ANVDMQVRSK RRARAKKTDT AGQEADNEEN VDSEAEELAD AARVAKERKF DFKRFSARFC SQKSIDTFVQ FTTYYRDLDD EQLKRAHRFF YRVAFKQELS ILLYRLDILN LFYRMIKGSE SLDSSKPIFR EWEEFVKQLT RRMIKKLNER PALFTELLFS KINATLFYLE YGHEKQTIST GGTRPPAELE VHPRAGTSRD EKLNVVVAAM LMDGQADLVK WLSEALRSAA NERSSWEAEN EIRQLESPEA AVSPSPLIEI KSDNDSIRTA TFRNGRLRLL MTSVGLERLG TEDVMGASWV VPASLDSATL SAVNSIIEKG LENPVKEIDG LDPRDQLRRK PTAEPKETYQ TTLDVDFGSE SEGEDAIPEG PLFPPNIRSK SNALKELKEK RRKRSKRDED KEPLDDAILE ERRRNREENA RARQAKIKSD LFVHDSDDES DEEADRAFFE HEEAVRKAQD KRVREALVTK ALEEDAANEQ SKSKKTTRRK RRGMDNGESD KDTDSEGQKK RRVTIGGFEM SDDEEEDDDV LMTGVGGDSS SQGVNGDDDT PPTSTEHEEW DLDKELEQHK STTIEATHDS DSEDGPVAAN RRRARAGFVI EDDSE // ID B8NYZ1_ASPFN Unreviewed; 652 AA. AC B8NYZ1; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 19-MAR-2014, entry version 18. DE SubName: Full=DNA repair protein (Tof1), putative; GN ORFNames=AFLA_115030; OS Aspergillus flavus (strain ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM OS 12722 / SRRC 167). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=332952; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 200026 / FGSC A1120 / NRRL 3357 / JCM 12722 / SRRC 167; RA Payne W.G.A., Dean R.A., Nierman W.C., Amedeo P., Caler E.G.A., RA Fedorova N.D., Maiti R., Joardar V., Inman J., Galinsky K.J., Yu J., RA Bhatnagar D., Cleveland T.E.; RT "Genome sequence of Aspergillus flavus strain NRRL 3357."; RL Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EQ963487; EED44801.1; -; Genomic_DNA. DR RefSeq; XP_002385556.1; XM_002385515.1. DR STRING; 5059.CADAFLAP00013421; -. DR EnsemblFungi; CADAFLAT00013421; CADAFLAP00013421; CADAFLAG00013421. DR GeneID; 7909501; -. DR KEGG; afv:AFLA_115030; -. DR KO; K10997; -. DR OMA; QFLENCY; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 652 AA; 75786 MW; 7377E08AAA25385C CRC64; MAVPRSERTT RDDGILKLML YLLRNIVVIA PNARLAADGD EEETSRSATI NAFQAQDVFA LLLTMCSNVG DDFNMQDVIL LEILFHLVKG VNVQKLFMDD AQRSAKHTDE LDTLLKQESS LRREYAKNAP TRHGRFGTMI WVKRDDAKVS TVSGQDVLKD SQATLQKMDE SKKWNRPQPR KTHEDSVLNN DFSTPAHLNS TASRNLRMFV EEFLDSGFNP LFTHVRKALE READRVVPIN SRQFFYTVAW FLDAERARRA RQQEMHLQNG KPMKELERDG FGLVASVLDQ ETLVFLNRSM QISFDQKDWE DLNAEMRCFT QILLTVQEMT QSLLEEDQEI AENIQNRIFY EETTHDRVLA IMREYKGQGF GYLDACTELS HVFLRMLERY SKENVDMQVR SRRRSRRKNM ETQVAAPEDN NEEHASDDED IMEAERICRE RKFDFKRFAA KFCNQKCVDT FVAFTKFFRE LNSDQLKRAH RYFYRIAFKQ EMSVLLFRVD ILNLFYTMIK GPGAMDSSKP IFKEWEELVR QVIRRMIKKI DQRPALITEL LFSKMNSTLF YLEYGHERQT LPSVRRAPAE LEVNPSEATT QEDKIKIVIG ALVMDGQADL VAWVSNVLGT AAEERESWEA YEDAQRDEAQ GAPRAPNPMI GM // ID B8PCQ2_POSPM Unreviewed; 1177 AA. AC B8PCQ2; DT 03-MAR-2009, integrated into UniProtKB/TrEMBL. DT 03-MAR-2009, sequence version 1. DT 19-MAR-2014, entry version 15. DE SubName: Full=Predicted protein; GN ORFNames=POSPLDRAFT_92790; OS Postia placenta (strain ATCC 44394 / Madison 698-R) (Brown rot fungus) OS (Poria monticola). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Polyporales; Postia. OX NCBI_TaxID=561896; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 44394 / Madison 698-R; RX PubMed=19193860; DOI=10.1073/pnas.0809575106; RA Martinez D., Challacombe J., Morgenstern I., Hibbett D., Schmoll M., RA Kubicek C.P., Ferreira P., Ruiz-Duenas F.J., Martinez A.T., RA Kersten P., Hammel K.E., Vanden Wymelenberg A., Gaskell J., RA Lindquist E., Sabat G., Splinter BonDurant S., Larrondo L.F., RA Canessa P., Vicuna R., Yadav J., Doddapaneni H., Subramanian V., RA Pisabarro A.G., Lavin J.L., Oguiza J.A., Master E., Henrissat B., RA Coutinho P.M., Harris P., Magnuson J.K., Baker S.E., Bruno K., RA Kenealy W., Hoegger P.J., Kuees U., Ramaiya P., Lucas S., Salamov A., RA Shapiro H., Tu H., Chee C.L., Misra M., Xie G., Teter S., Yaver D., RA James T., Mokrejs M., Pospisek M., Grigoriev I.V., Brettin T., RA Rokhsar D., Berka R., Cullen D.; RT "Genome, transcriptome, and secretome analysis of wood decay fungus RT Postia placenta supports unique mechanisms of lignocellulose RT conversion."; RL Proc. Natl. Acad. Sci. U.S.A. 106:1954-1959(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EQ966314; EED81354.1; -; Genomic_DNA. DR RefSeq; XP_002473464.1; XM_002473419.1. DR STRING; 104341.JGI92790; -. DR GeneID; 8144772; -. DR KEGG; ppl:POSPLDRAFT_92790; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1177 AA; 133430 MW; 9454BD43D69B4791 CRC64; MDRDDAISIS DDSGDEQYAD RRAILEPAIR NVVDALGGYE GESYRLGDEC YGCLKDLKKL WRKDDTDDDR TVARIFWETR LLPNDLIPIL LETAGKGLLE DKCAIACADL MTAMTWPIDL AEELKELDDD YDKGADYTQL LLSHLHYKVA VLKPGVMQAL FGIILPCLAK SSKERKERDT QVINVILYLI RNLAFIKDLP ANMHTSADQA EFSSLQTRLI KSLSDSNVFD LLLTIASNAN TDPMFNSWNA LVLEIFYLLF RGIQPSSLAI DQTQQPAQNL QRLLAVEDER KRNFARKATS RHSRFGTTIS VQLNPKKGQQ SHKEGDASGN ANAPDPEGSS RAFVLHRQQA INREAGSLLD LAKRQKTQKS KIIDELGRDD NLSLDAKLIL QNLARTFIEA CFNRHGPIDA YTFAAFLASL LKDIRAERPK ITEKDNLRLL YVAKWFLDFF LCVRAKEGPD SPWKFGLIAE VTERAWIVWV LKRMREAVEE KPKLWNELQA GIECLTQLIL VIDNMSSSGD EDVIDAAEVL QQQIIYNGEM LDIAFESLRT YKEGTQSLAY LDSSVYLAFA LMRMVERWGK KRGPGGEMYV RRKAKARRKK KSAAEGEGVP DVDEEEDNRE DEDIVHETMF TFDMFQQKFA HPDITQTLLA YLARYKEISS AEKMKRVVNL MHRQAVKAKA EGLFFNVSTL DLFKSILADQ KSLPKGQPYK DLVDLINFLL RKFFKAVEED SFLVVEAFFP KNRGHWKQYS SWEPEKSIKE DRPLDDNRFP LEVQVKKGYS WSEQLGIAIA CLVEEGKQSL IDWVKQILML TIGQRQRIIE DTDGSSSAVQ DVSDGEGDVS DAGSPTRTRG PSNEALAKFT DYLIPYINDE EANAATKDSY LKLVFRLVKF QVLDEKQLLT LPKAADELEW YIPAAILPDD LQRSLNIINQ FLEKPLDLEG KKASQLISKK RKRRRRRRSP SPDANEESSE DEIPKKKKEK KKKEKQQYKS AQFIEDSDAE LADMEAFLEK EKALREKTAK AAAETGRIAT MKPTGTKKRR KKAGDNGTAK KRRKRGGNAE VTEAEKNQSD GNDSDESELN IFGSPPRSPS TAQTSPEIEE EQVKPRPRPR PRPRVQAQPS ASDEAHENTQ DAVKPLSLTS LSPLDEASDR DPEGSHRATM SRKKGRLQLV LSDEEDD // ID B9FN33_ORYSJ Unreviewed; 1140 AA. AC B9FN33; DT 24-MAR-2009, integrated into UniProtKB/TrEMBL. DT 24-MAR-2009, sequence version 1. DT 19-MAR-2014, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=OsJ_17530; OS Oryza sativa subsp. japonica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; OC Ehrhartoideae; Oryzeae; Oryza. OX NCBI_TaxID=39947; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare; RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038; RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S., RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., RA Cong L., Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., RA Wang J., Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., RA Wang J., Wang X., Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., RA Zhang Z., Bao J., Han Y., Dong L., Ji J., Chen P., Wu S., Liu J., RA Xiao Y., Bu D., Tan J., Yang L., Ye C., Zhang J., Xu J., Zhou Y., RA Yu Y., Zhang B., Zhuang S., Wei H., Liu B., Lei M., Yu H., Li Y., RA Xu H., Wei S., He X., Fang L., Zhang Z., Zhang Y., Huang X., Su Z., RA Tong W., Li J., Tong Z., Li S., Ye J., Wang L., Fang L., Lei T., RA Chen C., Chen H., Xu Z., Li H., Huang H., Zhang F., Xu H., Li N., RA Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q., Li W., RA Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J., Gao L., RA Zheng W., Hao B., Liu S., Wang W., Yuan L., Cao M., McDermott J., RA Samudrala R., Wang J., Wong G.K., Yang H.; RT "The genomes of Oryza sativa: a history of duplications."; RL PLoS Biol. 3:266-281(2005). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000142; EEE62727.1; -; Genomic_DNA. DR PaxDb; B9FN33; -. DR Gramene; B9FN33; -. DR eggNOG; NOG328380; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; SQ SEQUENCE 1140 AA; 128190 MW; 0D10358172241159 CRC64; MTRSGGRFSS RFASGKSHLE IWCPSLRITR ADRNLVITAV KVLVFLTMPV EPSSENVAQQ IEYLWDLKAA LTRNVAMAVI VSLLEDPLDH LERASFTEDD WKLVQLVLTL FRNILAIQEI TLGQKASGEA TQLLCLADSF LELMFQENVM DLILVLTQHM DEPSGYLQQE NLLLLEIFHY LFLGRDPELI ARASTAGSKE HVEGNIDTSV HSLRLMMEEE ERKKRMFRQR NSEHHSISGI FTCTAVDGSK SLCKGNPNSA SANSLRKIRN VQRGPQKRIA WDNELLYTPR EGTMEMIRNF LEQFLSGGYN VLMQSVCDDI VKEHHSIQKS DITTFFKVAR FVLAFQHEKA SNAQKSNAAV QLPEASPSDH LDDNLPFLGD ICGPVAATLN EGMFNLVISR WREAYDSLKE THDYKTLSAA GSLMKNMIDM VYLVLKVLPD DSRESQTARV LLYKLFYDQT EQGLTQFLLN LFRSFDTHKQ PKSDLADLLG TIHIMLQLME KLQARGALRV AKRTRKGRKK KASKNKIENT NLNAEKMEQS NVDSTDGTKS ALESLPDLKN VDSVAEPPLT EQEKVVSNGM DAPDELAGTS VNLDSTSHCE GEPSRADNGE LKGNLIDEED GTSDSSLDDQ PPATSEVDFN VSRLISTLAN NSVVQNICWL LKHYKSNSFR TNHYIICMLR RFCEDLELAP MLYQLSLLTT FYDILADEKS SNSKEYTNIV NFLSKIVRKM LRVMKKQPLL FVDVLFWKTR KECHCIDADA LLSDITKDAT NKGGEIGSSK GWRGSINIAD SLGDDEVDLV IPHEPYNADK DDDSSSGEHE DVSKRSMGAT NKSNRILSFS DSEADDNDSS IQIEKNRNTV SRGSQNSEAP KRRGRSIFSE EQEKLMRDLY EKYKDDRKCT HLIAEALDPS GKISSVQVYR KLTQLGLRNA MKRRTKVPEA PLSAQELATQ TDQMLGEHNC DPKPETTRRR RKRQNVSHAS YEDNTTDGKS SDEETLQAIK SRTKNKKVPL VGFSPSTSQH QDGLADPDSD DETIGSMLRS GKKKRLLTPD NAMNIEKHQE SPDSTNTSNY SPEISQKQEA LQDTYSGDEI IDSMHRSGKK KRLLKSGFAA NTQEHEEPLK NIGQDDETIS SKASPKFVSP // ID B9RIP5_RICCO Unreviewed; 1047 AA. AC B9RIP5; DT 24-MAR-2009, integrated into UniProtKB/TrEMBL. DT 24-MAR-2009, sequence version 1. DT 14-MAY-2014, entry version 15. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=RCOM_1581430; OS Ricinus communis (Castor bean). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; fabids; Malpighiales; Euphorbiaceae; OC Acalyphoideae; Acalypheae; Ricinus. OX NCBI_TaxID=3988; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Hale; RX PubMed=20729833; DOI=10.1038/nbt.1674; RA Chan A.P., Crabtree J., Zhao Q., Lorenzi H., Orvis J., Puiu D., RA Melake-Berhan A., Jones K.M., Redman J., Chen G., Cahoon E.B., RA Gedil M., Stanke M., Haas B.J., Wortman J.R., Fraser-Liggett C.M., RA Ravel J., Rabinowicz P.D.; RT "Draft genome sequence of the oilseed species Ricinus communis."; RL Nat. Biotechnol. 28:951-956(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EQ973781; EEF49017.1; -; Genomic_DNA. DR RefSeq; XP_002513614.1; XM_002513568.1. DR GeneID; 8277061; -. DR KEGG; rcu:RCOM_1581430; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1047 AA; 119772 MW; FDE6813F685D0F48 CRC64; MQELSLICAG LGDEEEDNGK RIGYSKGENC LENLKDLLRC LRRDDPETRE VFKQVCNWKV VSKDLIPIIQ YCQVDRSLVL NAVKVLVFLT MPIEPSSNDI LQQTEYLWDL KSAITCSDTV GVIISLLEDP LEHLEREAFT EDDWKLVQLV LTLFRNILAI QDFSLLQKVG GSASHLLSLR DRFLELMFHE NVMDLVLIIT QHVCSSGYLR QDNLLLLEIF HYIFMGQEPE LIAKAQIKDS KDGSKAVYKG NPSSASHNVL LKPHKIHRSS TKRIVWDHGR LPSMKDDILV LLHDFLNQFL SGGYNVLMRS ISEDIEKEHH AIQNSDIVIF FKVAQFVTSF QYHKFSTFKP PNVEKDDSHS FPDEYVDNTL FKGDVCGPIA ASMNESMFLL VISRWRNAFD GLKQTNDYNF LSAAGSLMRI MIRMLDLVLK SLPEGSKESQ TARILLYKLF YDQTDQGMTQ FLLSLIKSFD THKQPKSDLA DLVEMIHLIV RLMENLQARG ALRVSKKSRK VRKKKALGSK RGTENELSGD GTKIQDQTLS SNTEQSIDLS ILQKINEENS TSDNQENNNI AVQDNQDNVA VQDSQENINN AIQPDKTEIS AQDIGNFGRN LPPMDKRKID HIDDDLTGSS DDSSSDEDLI ETHEVDFKVS SFVSTFANHN IIRNLCWLLR FYKSNSTNTN HYIVCMLQRI TDDLDLSPML YQLSLLTTFY DILDEQKSCP CKEYASIVDF LTTLIRRMLR KMKSQPLLFV EVLFWKSRKE CHYINAEYLL HELGHMKKEA KSWGNVLADG ELGSSQAKGW VPRSIADALG EDEADVVIAH EPYQNGGNAM EPATEGVSKR RRLVLTDEME MRIKELHEKY KDDGSCVRLI AESLDPAGHV SPAQVFNKLK QLGLKVSSKK RLRNVDKEFS TFPDQLVENG RNTRKKVRAF SKDQEEIIRA LFEQFKEHKR CSYMIANALA ADNSFTAAQV SRKLKQLGLH IPRQRRSETK LHLRDKELND FSVGEQVSDD ETLLSLRKRL VLPECVFIEI VESLLHEKLL VMMVWNF // ID B9WH30_CANDC Unreviewed; 1263 AA. AC B9WH30; DT 24-MAR-2009, integrated into UniProtKB/TrEMBL. DT 24-MAR-2009, sequence version 1. DT 16-APR-2014, entry version 23. DE SubName: Full=Topoisomerase 1-associated factor, putative; GN ORFNames=CD36_50890; OS Candida dubliniensis (strain CD36 / ATCC MYA-646 / CBS 7987 / NCPF OS 3949 / NRRL Y-17841) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=573826; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CD36 / ATCC MYA-646 / CBS 7987 / NCPF 3949 / NRRL Y-17841; RX PubMed=19745113; DOI=10.1101/gr.097501.109; RA Jackson A.P., Gamble J.A., Yeomans T., Moran G.P., Saunders D., RA Harris D., Aslett M., Barrell J.F., Butler G., Citiulo F., RA Coleman D.C., de Groot P.W.J., Goodwin T.J., Quail M.A., McQuillan J., RA Munro C.A., Pain A., Poulter R.T., Rajandream M.A., Renauld H., RA Spiering M.J., Tivey A., Gow N.A.R., Barrell B., Sullivan D.J., RA Berriman M.; RT "Comparative genomics of the fungal pathogens Candida dubliniensis and RT Candida albicans."; RL Genome Res. 19:2231-2244(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FM992692; CAX41471.1; -; Genomic_DNA. DR RefSeq; XP_002420393.1; XM_002420348.1. DR STRING; 573826.CD36_50890; -. DR GeneID; 8048090; -. DR KEGG; cdu:CD36_50890; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000094158; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1263 AA; 144750 MW; 70C43B5082A55064 CRC64; MSDFESGSDI DNYYEADEFD DFIEYSDNEL EQENSKPATG QSEVEEIEEP EEDRIRTLTT TLKPNETQAQ KLLKAHISVL VSALGGPDHT SDIQPPPYKL GHDALACLKD IKRWIRAVDE KKNNYEVALA CAESGLVSND LIVILCQWDD KMQKKETIKN KTTTEKTMLA CLELLVLLTW PVEFGKDLSE SQKLLYSEIK KVHVSYKKQI LMFNNGQLLK AAIRLVLPTI AKSRIDREPR DNQILKLVLF LIRNLLAIEP ANMSISNKSR KGANVTASDL PLGVTQDDIS INNVLSVFKK NKVLMLLLTI SGSIGSEFDR DMFGEICLES IYLIIKGLSA SDVLVKKNLD SAPVGAPSST QNRVPDAINA SQPLQSVTTT VGMQLQDLLA TESKKKKIQT QNIASRHGRF GSLLSIRSAD SNSFVVSGQE ALINTDSSLA KLDKSKKWKD RTYFKYDSDE YVNTTTPVYL NLTGQDILYN FVEQFLSGGC FNNLIECMGS RLTSQTDLNM VDELTLASYF FTIAWFLSYQ RERIGLNPQD RELNYGSVGA ALSEVNFILI IGYFRDSFSL KKWNSLHVAM ICFKELLQIS NSVFGKEITH QTGEDNGEIS QHEIDRELAE GIIRKLFSFN DFLSIIVQIP QTAAKHSPNY LRVSVSVVHI LLKAFETFAN EDVHLYIQSK RKQSKRNRKR VNNLDKSTED RLRDVIYASD EELDQSSAKE ITQERKLDFK KTEARFFHQT IVSTYINYLS RYEDLSSQEI KTCLSYFHRL FVVRKDFTGL YRLDFMQLLQ KLRNHLQRGS SLRLQVEEFI YYYMKKFKTA FERFPMPIEV LFPRFEDNEC KVYLATGEVY EKQETTSTSR SPRLAKDLEF VRDFGLDDQI KILVSQLHVQ EKQSLLKWLI QEMERIINDR ILNADSIAEL NASDQYRRLF INNGYLRFLL RIIGFDLPYT VEEVPELATT VDMEHLTKVT ELIKKWDSSQ PVIFEDDKVP SYFVRTREAG YDDDQYNEND QEYDFDDDSI AFETEANPNS NRNHVSELDH LEELERQLSS NGSRVNSKEH HGIKGKARKK SKEKKLSTPK NVRGLKRRRI PKDLLEDDSQ HVIKSAEFVH DSDDESDDEK DKAFFEREER MRSLLNDMGG IATSEQLKEI QEVWKNLETG GTNKVASTVA KAVKEVGLFV EESDDDDNAE EINSVPINEE TNRAIFEPAE TDTQQDLSED TSNTSEMESD TETAKRSFVE DGEEIPHVQS KKKRLVISDD EEE // ID C0NYP4_AJECG Unreviewed; 1110 AA. AC C0NYP4; DT 05-MAY-2009, integrated into UniProtKB/TrEMBL. DT 05-MAY-2009, sequence version 1. DT 16-APR-2014, entry version 15. DE SubName: Full=Topoisomerase 1; GN ORFNames=HCBG_08274; OS Ajellomyces capsulatus (strain G186AR / H82 / ATCC MYA-2454 / RMSCC OS 2432) (Darling's disease fungus) (Histoplasma capsulatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=447093; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=G186AR / H82 / ATCC MYA-2454 / RMSCC 2432; RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B., RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA Walk T., White J., Yandava C., Klein B., McEwen J.G., Puccia R., RA Goldman G.H., Felipe M.S., Nino-Vega G., San-Blas G., Taylor J., RA Mendoza L., Galagan J.E., Nusbaum C., Birren B.W.; RT "The genome sequence of Ajellomyces capsulatus strain G186AR."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG663377; EEH03334.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase; Reference proteome. SQ SEQUENCE 1110 AA; 127714 MW; 6332E935B5C48F76 CRC64; MEPESIQSGQ VVDPEVRAYV FNLVSALGGS GSSNTGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAETNLVNRD LIPILALLGD DIHDDKYKSR VSLACLELLV PLTWPLEIHS QMTVNHHRHI PYLQHSQVLY KRGILGNDTT AILRTIIRIA LPSMTTPRSD RSSRDEGILK LMLYLFRNIA IVTPSHLAAE GDEEEASKSA TINVFQQQDV FALLLAMCSN IGEDFIYQDV VILEILFHIV KGVDIKKLFM NDTQRNIAGT DDLEALLDKE SHLKREYAKT APTRHGRFGT MIWVKRDDEK VSTVSGQDVL KDDWTTMLKM DKSKKWDRPK HRKGDIDTSV NNFNVSSPLT PLATKHLRTF VEEFLDSGFN PLFSHIRKAI EREADRVTES TPRHFFYVVA WFLEAERVRR TRQQELRQQN AHLSRDFEPD GFQLVASVLN QETFIALTRH MQNCLDFKDW QDLNASMRCF TQILLTVQQM FHSDIAEDQD IAENILSRIF YEETTHDRIL AILRVYESQG FWYLDACTEL AHVFFRLLEQ YSKQNEYMQI RSRRRARRKQ RKKAAPNPEN GEAQDGDESE AEDLTMEDAT KTIVERSFNF QRFAAKFCTQ NSVNTFLALT AYYRELNEEQ LKRAHRFFYR VAFKQELSVL LFRVDIISLF YKMIKGPRGL DSTKPIYVEW EELTRRIIRK LVKKLEERPE LITEMLFSKI NATVFYLEYG HERQTVSQSK AAAELEVKPG AANTLDSKLG IVVAALLLEG KESLVQWLIK TIDTAVNERR SWELEAEARR SESGEERTAN TPPSIAVIPF DDACRTAMFK NGRFRLLMTS AGLERLGVED TLGSSWIIPS SLSARTLEET KKSIEKHKEN PPTEFDGLEP RDLLRRKRDI DTTLSHQRTS GEVDFGNDSE GEDDIDDILF PPNLRTRADT LDELKKKRLR RGKKNGKDGD VLDEASLEAR RLARHANALE RQRKIKSSLY IHASDEESDE EADREFFARE EERRRNQAMR IKQALLSDAT GGDDLPDQNS SSRARKRKGT ADEDEVNKRR RNDHLLPDSD EEVDLTSIDG HQDDDEENGL MVTQDEPSSS SETTSMSFGW // ID C0S5P9_PARBP Unreviewed; 1193 AA. AC C0S5P9; DT 05-MAY-2009, integrated into UniProtKB/TrEMBL. DT 05-MAY-2009, sequence version 1. DT 22-JAN-2014, entry version 9. DE SubName: Full=Mating-type switching protein; GN ORFNames=PABG_02739; OS Paracoccidioides brasiliensis (strain Pb03). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Paracoccidioides. OX NCBI_TaxID=482561; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Pb03; RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345; RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., RA Goldberg J., Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., RA Grynberg M., Gujja S., Heiman D.I., Henn M.R., Kodira C.D., RA Leon-Narvaez H., Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., RA Morais F.V., Pereira M., Rodriguez-Brito S., Sakthikumar S., RA Salem-Izacc S.M., Sykes S.M., Teixeira M.M., Vallejo M.C., RA Walter M.E., Yandava C., Young S., Zeng Q., Zucker J., Felipe M.S., RA Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G., Puccia R., RA San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.; RT "Comparative genomic analysis of human fungal pathogens causing RT paracoccidioidomycosis."; RL PLoS Genet. 7:E1002345-E1002345(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS544806; EEH20508.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1193 AA; 135937 MW; 61A77A9FE2EACAFC CRC64; MKLEPAQPVQ VVDPEVRAYV YSLITALGGS GSSDTGQYVL GDDALACLRD LKKWLKFYDE KANRMDVARC LAEANLVNRD LIPILKLYGN FAPYGKQMSR IALACLELLV PLTWPLEIHS QMTVNHHRHI PYLQHSQVLY KRGILGNDTT ALLRTIIRIA LPSMTTARSD RSSRDEGILK LMLYLFRNLA VITPAPHLAT EGDEEEASKS ATINAFQQQD VFALLLTMCS NMGNDFNFQD VIILEIIFHI IKGVDVKKLF MDKAQRSVAG TDDLEVVLDK ESHLKREYSK TAPTRHGRFG TMIWVKRDDE KISTLSGQDM LKDDWTTMMK MDKTKRWNKP KHKKGVVDLS VNNFNISTPL TSSATEHLRT FVEEFLDSGF NPLFSNLRKA IEREADRVTE FTPRQFFYSI AWFLEAERFR RSRKQEIRQQ NKNVTRDIEP DSFQLVAGVL NQETFIALSR HMQNCLDYKD WQDLNASILC FTQILLTVQD MFHSSISEDQ DIAENILNRI FYEETTHDRI LAILKGYEGQ GFWYLDACTE IAHVFLRLLE QYSKQNEHMQ IRSRRRARRK QRKEAASNPE NPEADNNSES EEEDTAVADA SKTIVERAFD FQRFAAKFCT QKSVNTFLAL TSYYRELNDS QLKRAHRFFY RVAFKHELSV LLFRVDIISL FYRMIKGPGG LDTTKPSFAE WEEFVRRIIR KLVKKIGERP ELVTEMLFSK INATVYYLEY GHEKQTLSES QAAAELEVKP NAASTLFDRI EIVVAALCLE GKQNLIQWLV KTLECAVNER RSWELEAEAR QAESGEGQTA NPPSITVIPH DDACRNAMFK NGRLRLLMTL AGLERLGVED IIDASWIVPS SLSAETLEET QKSIEKNLEN PPTEFNGLNP SDLLRRKRDV NPRKSSDERG PGDVDFGNDS EGEDDIDGIL FAPNLRTRTD TLDELKKKRL KRGKQRRGQE GDDPDDAVLE ARRLAREANA LERQRKIKSS LYIHASDEES DEEADKEFFA REEERRKAQA KRVREALSTG RVAKSDGDDS IRPKSSSKGR KRKSAANDGQ WGKRRRSNPL SDDSDGDNAS DNEDDSLMAV QEASSPSESV SASASASIPR PGRTSENTTP PTSTGRDPRD EMNDDYFEIN PFSFSSIENN GKAAEGNADD KDEEDEAIQK PRREPRRYCG FIIDSDSESE VGG // ID C1FE20_MICSR Unreviewed; 615 AA. AC C1FE20; DT 26-MAY-2009, integrated into UniProtKB/TrEMBL. DT 26-MAY-2009, sequence version 1. DT 14-MAY-2014, entry version 12. DE SubName: Full=Predicted protein; GN Name=TIM; ORFNames=MICPUN_107338; OS Micromonas sp. (strain RCC299 / NOUM17) (Picoplanktonic green alga). OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales; OC Micromonas. OX NCBI_TaxID=296587; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=RCC299 / NOUM17; RX PubMed=19359590; DOI=10.1126/science.1167222; RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L., RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E., RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M., RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H., RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., RA Gready J.E., John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., RA Moreau H., Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., RA Piegu B., Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., RA Zelensky A., Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., RA Van de Peer Y., Grigoriev I.V.; RT "Green evolution and dynamic adaptations revealed by genomes of the RT marine picoeukaryotes Micromonas."; RL Science 324:268-272(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP001574; ACO68489.1; -; Genomic_DNA. DR RefSeq; XP_002507231.1; XM_002507185.1. DR GeneID; 8250547; -. DR KEGG; mis:MICPUN_107338; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 615 AA; 70234 MW; 1A9070DC346A97D0 CRC64; MYSAITFAEA HLQSLVSSLG RRRDSRLRDS PYVKDPMCHE TLQDILRFLR HDQSHERPVA FLLHSWDFLQ THLLPLVLTY HGSESLILDS VKLLVFLTLP ADASAKNVSE QRRYLSHTLE NLLQRREIFP ILFSCLRGPL ERLESSNLRL KDDDGKTIQL FLTFIRNCLL TDERHRLCTD VKFTCHVKER IIQMLFETHV IDVLIQVAKD VRKKQLSDDS ALLTEIFHLI FQSCTPRQLL RGFDGLGLKE NQSGQRDTFG SVRRLSVRHS HFGGRNSTSN ASPSITNRPV ATSRQYFGEN ISLDESSVTP IQATTLERLV ELARTLVKGA LNEVLLASWI SIRHRQQLET ESEEKALRVK SFLCLSYFFV SYTQISCEVN EMDAPNSAGI SNLFDKEVFA WLQTTWAEHE QTKNVWGVVL VSGLVKEMFA MMTTIMSRGV QYDRFACEAV LSEIFVKSNS DDLLQRASSV VRSYRTGEAP LIYLANATEV MHLGYGLKRL IDPRFVINLK DIFYEKTISN HIRLLAFTNL NSKRLNVMLL NYVDEIMERG MENTLHDVSS LETLFAAAGN NEISAFLVPK GGISAAIVNF MNGIYMDERG EHMDYKRSKF LGTVC // ID C1G2R3_PARBD Unreviewed; 1142 AA. AC C1G2R3; DT 26-MAY-2009, integrated into UniProtKB/TrEMBL. DT 26-MAY-2009, sequence version 1. DT 16-APR-2014, entry version 17. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=PADG_01229; OS Paracoccidioides brasiliensis (strain Pb18). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Paracoccidioides. OX NCBI_TaxID=502780; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Pb18; RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345; RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., RA Goldberg J., Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., RA Grynberg M., Gujja S., Heiman D.I., Henn M.R., Kodira C.D., RA Leon-Narvaez H., Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., RA Morais F.V., Pereira M., Rodriguez-Brito S., Sakthikumar S., RA Salem-Izacc S.M., Sykes S.M., Teixeira M.M., Vallejo M.C., RA Walter M.E., Yandava C., Young S., Zeng Q., Zucker J., Felipe M.S., RA Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G., Puccia R., RA San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.; RT "Comparative genomic analysis of human fungal pathogens causing RT paracoccidioidomycosis."; RL PLoS Genet. 7:E1002345-E1002345(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS572751; EEH45079.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1142 AA; 130126 MW; 25890DAE3D346832 CRC64; MKLEPAQPVQ VVDPEVRAYV YSLITALGGS GSSDTGQYVL GDDALACLRD LKKWLKFYDE KANRMDVASQ MTVNHHRHIP YLQHSQVLYK RGILGNDTTA LLRKIIHIAL PSMTTARSDR SSRDEGILKL MLYLFRNLAV ITPAPHLATE GDEEEASKSA TINAFQQQDV FALLLTMCSN MGNDFNFQDV IILEIIFHII KGVDVKKLFM DKAQRSVAGT DDLEVVLDKE SHLKREYSKT APTRHGRFGT MIWVKRDDEK ISTLSGQDML KDDWTTMMKM DKTKRWNKPK HKKGVVDLSV NNFNISTPLT SSATEHLRTF VEEFLDSGFN PLFSNLRKAI EREADRVTEF TPRQFFYTIA WFLEAERFRR SRKQEIRQQN KNVTRDIEPD SFQLVAGVLN QETFIALSRH MQNCLDYKDW QDLNASMLCF TQILLTVQDM FHSSISEDQD IAENILNRIF YEETTHDRIL AILKGYEGQG FWYLDACTEV AHVFLRLLEQ YSKQNGHMQI RSRRRARRKQ RKEAASNPEN PEADNNSESE EEDTAVADAS KTIVERAFDF QRFAAKFCTQ KSVNTFLALT SYYRELNDSQ LKRAHRFFYR VAFKHELSVL LFRVDIISLF YRMIKGPGGL DTTKPSFAEW EEFVRRIIRK LVKKIGERPE LVTEMLFSKI NATVYYLEYG HEKQTLSESQ AAAELEVKPN AASTLFDRIE IVVAALCLEG KRNLIQWLVK TLECAVNERR SWELEAEARQ AESGEGQTAN PPSITVIPHD DACRNAMFKN GHLRLLMTLA GLERLGVEDI IDTSWIVPSS LSAETLEETQ KSIEKNLENP PTEFNGLNPS DLLRRKRDVN PRKSSDERGP GDVDFGNDSE GEDDIDGILF APNLRTRTDT LDELKKKRLK RGKQRRGQEG DDPDDAVLEA RRLAREANAL ERQRKIKSSL YIHASDEESD EEADKEFFAR EEERRKAQAK RVREALSTGR VAKSDGDDSI RPKSSSKGRK RKSAANDGQR GKRRRSNPLS DDSDGDNASD NEDDSLMAVQ EASSPSESVS ASASASIPRP GRTSENTTPP TSTGRDPRDE MNDDYFEINP FSFSSIENNG KAAEGNADDK DEEDEAIQKP RREPRRYCGF IIDSDSESEV GG // ID C1H6D9_PARBA Unreviewed; 1179 AA. AC C1H6D9; DT 26-MAY-2009, integrated into UniProtKB/TrEMBL. DT 26-MAY-2009, sequence version 1. DT 16-APR-2014, entry version 20. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=PAAG_06330; OS Paracoccidioides lutzii (strain ATCC MYA-826 / Pb01) (Paracoccidioides OS brasiliensis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Paracoccidioides. OX NCBI_TaxID=502779; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-826 / Pb01; RX PubMed=22046142; DOI=10.1371/journal.pgen.1002345; RA Desjardins C.A., Champion M.D., Holder J.W., Muszewska A., RA Goldberg J., Bailao A.M., Brigido M.M., Ferreira M.E., Garcia A.M., RA Grynberg M., Gujja S., Heiman D.I., Henn M.R., Kodira C.D., RA Leon-Narvaez H., Longo L.V.G., Ma L.-J., Malavazi I., Matsuo A.L., RA Morais F.V., Pereira M., Rodriguez-Brito S., Sakthikumar S., RA Salem-Izacc S.M., Sykes S.M., Teixeira M.M., Vallejo M.C., RA Walter M.E., Yandava C., Young S., Zeng Q., Zucker J., Felipe M.S., RA Goldman G.H., Haas B.J., McEwen J.G., Nino-Vega G., Puccia R., RA San-Blas G., Soares C.M., Birren B.W., Cuomo C.A.; RT "Comparative genomic analysis of human fungal pathogens causing RT paracoccidioidomycosis."; RL PLoS Genet. 7:E1002345-E1002345(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS572828; EEH35282.1; -; Genomic_DNA. DR RefSeq; XP_002791590.1; XM_002791544.1. DR GeneID; 9094984; -. DR KEGG; pbl:PAAG_06330; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1179 AA; 134115 MW; 1003B0D4D3111708 CRC64; MALHKDTGSE IVVEVQIVHL ENPRSLGGSG SSDTGQYVLG GDALACLRDL KKWLKFYDEK ANRMDVARCL AEANLVNRDL IPILKLYGNF AHDGKHMSRI ALACCEDLSL LHPRHIPYLQ HSQVLYKRGI LGSDTAALLR TIIRIALPSM TTTRSDRSSR DEGILKLMLY FFRNLAVITP APHLATEGDE EEASKSATIN AFQQQDVFSL LLTMCSNMGN DFNFQDVIIL EIIFHIIKGV DVKKLFMDKA QRSVAGTDDL EVVLDKESHL KREYSKTAPT RHGRFGTMIW VKRDDEKIST LSGQDMLKDD WTTMMKMDKT KRWNKPKHKK GVVDLSVNNF NISTPLTSSA TEHLRTFVEE FLDSGFNPLF SNLRKAIERE ADRVTESTPR QFFYTIAWFL EAERVRRSRK QEVRQQNKNF TRDIEPDSFQ LVAGVLNQET FIALSRHMQN CLDYKDWQDL NASMLCFTQI LLTVQDMFNS SISEDQDIAE NILNRIFYEE TTHDRILAIL KGYEGQGFWY LDACTEIAHV FLRLLEQYSK QNEHMQIRSR RRARRKQRKE AASNLENPEA DNTSESEEED TAVADASKTV VERAFDFQRF DAKFCTEKSV NTFLALTSYY RELNDSQLKR AHRFFYRVAF KHELSVLLFR VDIISLFYRM IKGPGGLDTT KPSFAEWEEF VRRIIRKLVK KIGERPELIT EMLFSKINAT VYYLEYGHEK QTLSESQAAA ELEVKPNAAS TLFARIEIVV AALCLEGKQN LIQWLVKTLE CAVNERRNWE VEAEARQAES GEGQTSNPPS ITVIPLDDAC RNAMFKNGRL RLLMTLAGLE RLGVEDTIDT SWIVPSSLSA ETLEETQKSI EKDLENPPTE FNGLNPSDLL RRKRDINPRA SSHERASGDV DFGNDSEGED DIDGILFPPN LRNRTDTLDE LKKKRLKRGK QRRGQEGDDP DDAVLEARRL AREANALERQ RKIKSSLYIH ASDEESDEEA DKEFFAREEE RRKAQAKRVR EALSTVKAAK SDGDDSIRPK SSSKGQKRKS AANDGQWGKR RRSNPLSDDS DGDNVSDNED DSLMAVQEAS SPSESLCASA SALIPRSGRT SDNTTPQTST GRDPRDGMND DYFEINPFSF SSIENNGKAA EGNSDDKDEE DEAIQKPSRE PRRYCGFIID SDSESEVGG // ID C1MKK6_MICPC Unreviewed; 318 AA. AC C1MKK6; DT 26-MAY-2009, integrated into UniProtKB/TrEMBL. DT 26-MAY-2009, sequence version 1. DT 14-MAY-2014, entry version 12. DE SubName: Full=Predicted protein; GN ORFNames=MICPUCDRAFT_64469; OS Micromonas pusilla (strain CCMP1545) (Picoplanktonic green alga). OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales; OC Micromonas. OX NCBI_TaxID=564608; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CCMP1545; RX PubMed=19359590; DOI=10.1126/science.1167222; RA Worden A.Z., Lee J.H., Mock T., Rouze P., Simmons M.P., Aerts A.L., RA Allen A.E., Cuvelier M.L., Derelle E., Everett M.V., Foulon E., RA Grimwood J., Gundlach H., Henrissat B., Napoli C., McDonald S.M., RA Parker M.S., Rombauts S., Salamov A., Von Dassow P., Badger J.H., RA Coutinho P.M., Demir E., Dubchak I., Gentemann C., Eikrem W., RA Gready J.E., John U., Lanier W., Lindquist E.A., Lucas S., Mayer K.F., RA Moreau H., Not F., Otillar R., Panaud O., Pangilinan J., Paulsen I., RA Piegu B., Poliakov A., Robbens S., Schmutz J., Toulza E., Wyss T., RA Zelensky A., Zhou K., Armbrust E.V., Bhattacharya D., Goodenough U.W., RA Van de Peer Y., Grigoriev I.V.; RT "Green evolution and dynamic adaptations revealed by genomes of the RT marine picoeukaryotes Micromonas."; RL Science 324:268-272(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG663736; EEH59387.1; -; Genomic_DNA. DR RefSeq; XP_003056011.1; XM_003055965.1. DR GeneID; 9681962; -. DR KEGG; mpp:MICPUCDRAFT_64469; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 318 AA; 36440 MW; 253B7D4A12D5CB23 CRC64; MHLEKEVFDI AHLQSLATSL GKRQKHNEDC VYVRDPQCHE TLQDILRFLR RDTTSSRSIM LLLHGWNLVE KDLIPLLLNY RGEASVFLDS IKLLVFLTLP ADQESSSYAQ QRRCILNTLT ALLQSQEIIP VLFSALLVSL ERYEVNQLRS NDEDAKVIQL FLTLIRNLLA GTDYRVAGSR GQDHVVLKEK LLTVLFDLQF PALLSQMAKD ARKNPFTEES ALLVEIFDLL FLDQNPSLLA LFFDQQRREA PSVKAAKNSQ SWTTCQQDRH KHVRHSRFGS RVVSASSGDT VNSKRTGFRS FLLTRRSYFG KVVSMNLF // ID C3Z057_BRAFL Unreviewed; 201 AA. AC C3Z057; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 03-SEP-2014, entry version 14. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=BRAFLDRAFT_85678; OS Branchiostoma floridae (Florida lancelet) (Amphioxus). OC Eukaryota; Metazoa; Chordata; Cephalochordata; Branchiostomidae; OC Branchiostoma. OX NCBI_TaxID=7739; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S238N-H82; TISSUE=Testes; RX PubMed=18563158; DOI=10.1038/nature06967; RG US DOE Joint Genome Institute (JGI-PGF); RA Putnam N.H., Butts T., Ferrier D.E.K., Furlong R.F., Hellsten U., RA Kawashima T., Robinson-Rechavi M., Shoguchi E., Terry A., Yu J.-K., RA Benito-Gutierrez E.L., Dubchak I., Garcia-Fernandez J., RA Gibson-Brown J.J., Grigoriev I.V., Horton A.C., de Jong P.J., RA Jurka J., Kapitonov V.V., Kohara Y., Kuroki Y., Lindquist E., RA Lucas S., Osoegawa K., Pennacchio L.A., Salamov A.A., Satou Y., RA Sauka-Spengler T., Schmutz J., Shin-I T., Toyoda A., RA Bronner-Fraser M., Fujiyama A., Holland L.Z., Holland P.W.H., RA Satoh N., Rokhsar D.S.; RT "The amphioxus genome and the evolution of the chordate karyotype."; RL Nature 453:1064-1071(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG666567; EEN54116.1; -; Genomic_DNA. DR RefSeq; XP_002598104.1; XM_002598058.1. DR STRING; 7739.JGI85678; -. DR GeneID; 7241014; -. DR KEGG; bfo:BRAFLDRAFT_85678; -. DR eggNOG; NOG297449; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 201 AA; 23262 MW; E8E76163C874191E CRC64; MAFADEEVWT VLSRKLYELL QLDWENRQEE DSMLIERILL LVRNILHVPA DPEEEKRTDD DASVHDQVLW AIHQSGFDDL LKFIASSDSE QQWCMHVLEI VSLMCREQTS EQLARAGQGR SAGEKAQDEL ELQAVRQREL ADRQARIRAL GTRHSRFGGT FVVQGMKSIS DKDLIYHQPL KEISQVSFDR EKVRKSLRLC G // ID C4JH56_UNCRE Unreviewed; 1001 AA. AC C4JH56; DT 07-JUL-2009, integrated into UniProtKB/TrEMBL. DT 07-JUL-2009, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=UREG_02629; OS Uncinocarpus reesii (strain UAMH 1704). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Onygenaceae; Uncinocarpus. OX NCBI_TaxID=336963; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=UAMH 1704; RX PubMed=19717792; DOI=10.1101/gr.087551.108; RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., RA Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., RA Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., RA Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J., RA Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.; RT "Comparative genomic analyses of the human fungal pathogens RT Coccidioides and their relatives."; RL Genome Res. 19:1722-1731(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH476615; EEP77780.1; -; Genomic_DNA. DR RefSeq; XP_002543113.1; XM_002543067.1. DR GeneID; 8443074; -. DR KEGG; ure:UREG_02629; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1001 AA; 114257 MW; 310EE8A4F5D4F88B CRC64; MATPRSERST RDEGIIKLML YFFRNIAVLT SPTNLTVDGD DDKATRSATI DAFQQQDIFA LLLTMCSTMG EDFTFQDVII LEILFNLVKG VDVKQLFKPA ERAGITKANE LESLLQKESE LNREHAKTAP TRHGRFGTMI WVKRDDEKFS TVSGQDVLKG DRATLLKMDK SKKWNKPRFK REVVDPSSNN FNVKVMLTPS ASKNLQTFVE EFLDSGFNPL FTHLRKAIER EAERITESTS RQFWYVVSWF LHAERVRREH QKEARQQARG RAKDIEPDDF SLVASVLNQE TFVNLNRYMQ HCLDYKDWQD LTAGMKCFTQ ILLTVQEMAI STLEEDQEIA ENIQNRIFYE ETTHDRILVI LRNYNDQGFW YLDACTELAH VFLRMLEQYS KQNVDMQVRS RRRGRRKKTQ TTAPDQDGVE EDGGHGSEAE DRAEANRTAV ERSFDFKRFS LKFCTQKSVD TFVAFTNYYR ELDSEQLKRA HRFLHRVAFK QDRGILLFRL DIISLLFKMI KGPEGLDASK SSFKEWEELV RHLFRNLVRK LKQRPELVVE LLFSKINSTL FYLEYGYEKQ SLSESKPAAE LEIKPGSAST LDEKIRIVVA ALIQDDKLPL VKWLGGVLDS AISERQSWEM EAEARAASST EEQAEAKPPS IAVVPEDDDC RDAMFRNGRL RLLMTLAGFK CFDEDELSAS WIISSSISSS TLKESSTLIE KHCENPVEDI DGADPRDLIR RKRTTADLKA SHHESIESVH FGSDSEGEDE ILFPPNLVQR SKAAKGRKLT RRKRKDGDDN ESGLDDAELE ARQAARKRNA LERQRKIKSD LYVRPSDDET DEEADARFFA KENERRLAQA ARIQKALETG VLENSVPQKQ TKPKASRKRK ANSIPESDIE DDANIPSKRR RDEAGGESDS ADEDGVDSGS PSSRGSSTPT PDIDPMPMRS PSVELPWSAG VDQMLKGAIP DNEKESGASD NEEEDDDDLV LTARSTRRRA MAGFVFESDS E // ID C4R350_PICPG Unreviewed; 1185 AA. AC C4R350; DT 07-JUL-2009, integrated into UniProtKB/TrEMBL. DT 07-JUL-2009, sequence version 1. DT 22-JAN-2014, entry version 22. DE SubName: Full=Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p); GN OrderedLocusNames=PAS_chr2-2_0013; OS Komagataella pastoris (strain GS115 / ATCC 20864) (Yeast) (Pichia OS pastoris). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Komagataella. OX NCBI_TaxID=644223; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=GS115 / ATCC 20864; RX PubMed=19465926; DOI=10.1038/nbt.1544; RA De Schutter K., Lin Y.-C., Tiels P., Van Hecke A., Glinka S., RA Weber-Lehmann J., Rouze P., Van de Peer Y., Callewaert N.; RT "Genome sequence of the recombinant protein production host Pichia RT pastoris."; RL Nat. Biotechnol. 27:561-566(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN392320; CAY69924.1; -; Genomic_DNA. DR RefSeq; XP_002492204.1; XM_002492159.1. DR STRING; 644223.PAS_chr2-2_0013; -. DR EnsemblFungi; CAY69924; CAY69924; PAS_chr2-2_0013. DR GeneID; 8198972; -. DR KEGG; ppa:PAS_chr2-2_0013; -. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1185 AA; 136115 MW; 48BAC199DBC9C94D CRC64; MSLYAEDPEL DDFIIDNEPS GTHHIVESSS DEEERFTEKS SGPIKQARST QPELQNHDEE LRKRVIRSHI AILCSSLGGI DHSTESKLSI YKLGGEALVC LKDIKRWIRT VDHEMNNWDV ASACADCNLV PNDLIHIMTQ WELDNQGKKV ENPKYWESIV VSSLELLVML TNPLVLEFEK TDEKKIVLYP KLKKAHLTYK NRILNFQGGL TLKAVLRILL PLLVSNKRST RDLKVMYLCL TFIRNVIRIE PADARINSKK TTKQLNISSN YPVGVSPDDV DVNRVMIILK KTKVLSLILT LTSNADKAYN DTMLHQLCLE CLYYLLNGIK VSSFILGEPQ NEHDSSMTEA GLELSDLVSK EKNIFDGIKR NHSSRHSNFG TLLSLQRGNE RITISGSPKD LLATLDKTKS HSNSRTYTRI AKNESTNRDL DSQLRLHKAK RLDSEGLKIL IEFLQSFMEE SFDPFFSKLI HTYSSDDNIR SYLMYAYFYV LQWILEYFQG LKKKDFYNIA SAFDHSNVIL ILRKVSEYHD LKEFNMCYVL IGCLDELLSN ACFMLSTNDS QLIDRAEGLL NSIVGQEAYL ELFISIVSSA HKVSTQFVDK AAQFLSTIFK STEAMVRFYD SDQVIIQKSK STKKRNSRIA ATEEEDNEPG EVDDIQMRTL AFKKKADIKS IRTKLIRNET VYLFISIWER LDDVDAAHFK LALHFFYDVF VKYELVLHLY RLDFLKTLYW VNANHLVLPI GKSTRRDLQS FSKYFMSKLY QLMNHSKEIL VEMPFCSLNP DVSIRQYFLT GEKPDVHEKT AREYKVGKLE FTEELNLEQK IGILVSLLKA LNLDLVEWLK HNVETIVDSM SSWNDRDIVT GEDLTSKDED LYILQASNKA YNSAIRRNPT FRKLLELVGY DIPTHTGMKC VLQKHIDQSS LEICLSFIKK YLEEDYVPSN HAEVEELVNL KKPAPNSRNG TDEFNGADNQ HNDQEDDLFV NESDDDNQIE FEIGENGQRR IVNDNLDIIE QQLKFNERRN RGVARPPSKR AKRNRVISSE DEDISDGLSS LNKKVKRSKR KQARRIRKTI FDSNNEIGEE SSGEGAKRKP SNLDLNIKSS EYIDDSDLEL TDEEVFFFRE DTLRSMLNES NGQLTAAQLQ ELSNITINHL KSRSLTGGDL ENLTIKNSIA KEGTPISFAQ PIDDE // ID C4XZ83_CLAL4 Unreviewed; 1245 AA. AC C4XZ83; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 13-NOV-2013, entry version 13. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=CLUG_01265; OS Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida OS lusitaniae). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Metschnikowiaceae; Clavispora. OX NCBI_TaxID=306902; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 42720; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH408077; EEQ37142.1; -; Genomic_DNA. DR RefSeq; XP_002617806.1; XM_002617760.1. DR GeneID; 8499257; -. DR KEGG; clu:CLUG_01265; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1245 AA; 142184 MW; B209D4FE4664E1E1 CRC64; MSDYKEDEEL DDFIVSDEEV PSPQEEETEA PQQDRITGLT TMLRVNESFT SKVLRAHISV LVSALGGPDH SSEDGLYKLG HDALACLKDI KKWIRSVDDR NNSSEVALAC AENGLVNNDL TVILCQWDKP PPGVKRTKTT DKIMLACLEL LVLLTWPIEV NRKTLLKDYT SKTNARRAQL VYKKHILAYQ GGHTLKAIIR LGLRAMQLPR EDREPRDVNI LRLILFFIRN LLFIEPLPAS KSPKAITNSS DLPNGMSPED VGLNAVIAAF ENNKVLLFLT SIAHSVSSEF NDETFGVLVI ECLSLLTRGI KTESLFSTIP KAPVSDISEN VPPASSAAGL QLQDLLSEEE KRKRRQKNTV STRHGRFGTL LSIQSSDNSS YYTISGQEAL ASTLESLDKL DRTKKWHKTS GFKYDSNEYV KNSTIYLNSH SIKIIKRFID SLLSSGSYNN LLSFVGRHLT NISNDHDLGR KVILDSVDPH ELASYFLVIS WFFSYKRDRN NYYARNKLAP LDEEDSLDYG SVGSSLSEIN FILLTSYLRS AYEAKDYDSL HVALICMRGM LQISNAIFSS ERTQREMNPS SEEDINHDRE LAEGIIRKLF SQKQFLDMIV NIPRQASRHS PEYLSVVVSV VHIVLKCFET LANEDVKLYI QGRRRVNKLG NQSGLNHDMD RQHWHLIDAG SDEEDFEQEI RYINQERKLD FKNTEVRFFH TETVSTHIAY LSRFEDLTHE EIKRGISFFH RLFVVRKDFA ALYRLDFMNL LYRLRAYLPR SSNIRRHVDD FIVYFMKKFK TALDRFPVAI ELLFPRFENL EMKGFLSTGD LESTSTSSSI GVTSARGLPK SSYFSEDAPQ PRAAAILRFN DDNLTLDEKI GVLIYHLIKK KNGIKILKFL IGELERLTAL KEKGINNLML RLNLTNRKLL INEPHLRLLV ESIGFDLPFL QNDETSLKTS VEASTLVEAK NSIDKWLKLH EEGVGDIEPF LDQVHQEIFT KEQLNFGIIA LSDVRSGRPI DLATAEVIGL RQDQIGKLIG LAKRKEYDEM VAAQYALEDE DYDIEPSDAE DNSSISGRRR KRMKNKSSET TLSDSVIDDL DDLPKKQRRS RREILKRSLD SDDDAPVKSS EMVNDSDDES DDEKVKSFYE KEEQLRQLIS STGGIMNKTQ LEIFKESWQK IVNTNEDSQV KTAISRAASL FVDDSDENDD ESQPKEFSHQ NTTDELQLNQ KRTQDEGHVM VSRKRRIVLE EEDEE // ID C4YR34_CANAW Unreviewed; 1263 AA. AC C4YR34; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 11-DEC-2013, entry version 16. DE SubName: Full=Uncharacterized protein; GN ORFNames=CAWG_04533; OS Candida albicans (strain WO-1) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=294748; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=WO-1; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000311; EEQ46187.1; -; Genomic_DNA. DR HOGENOM; HOG000094158; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1263 AA; 144882 MW; FF1E042DECEE49FE CRC64; MSDYESGSDI DNYYEADEFD DFIEYSDNEV EQEKSKPTPG QIEVEEIEEP EEDRIRTLTT TLKPNETQAQ KLLKAHISVL VSALGGPDHT SDIQPPPYKL GHDALACLKD IKRWIRAVDE KKNNYEVALA CAESGLVTND LIVIMCQWED KMQKKESIKN KTTTEKTMLA CLELLVLLTW PVEFGKDLSE SQKLLYSEIK KVHVSYKKQI LMFNNGQLLK AAIRLVLPTI AKSRIDREPR DNQILKLVLY LIRNLLAIEP ANLSISNKSR KGASVTASDL PLGVTQDDIS INNVLSVFKK NKVLMLLLTI SGLLGTEFDR DMFGEICLES IYLIIKGLSA SEVLVKKNLG STPVAAPSQN TVPDAINASQ PLQPVTTTVG MQLQDLLATE SKKKKIQTQN IASRHGRFGS LLSIRSADSN SFVVSGQEAL INTDSSLAKL DKSKKWKDRT YFKYDSDEYV NTSTPVYLNL TGQDILYNFV EQFLSGGCFN NLIECMGSRL TSQTDLNMVD ELTLASYFFT ISWFLSYQRE RIGLDPENKE LNYGSVGAAL SEVNFILIIG YFRDSFSVKK WNSLHVAMIC FKELLQISNS VFGKEITNQT GEGDEISQHE IDRELAEGII RKLFSFNDFL SIIVQIPQTA AKHSPDYLRV SVSVVHILLK AFETFANEDV HLYIQSKRKQ SKRNRKRVNN LDKSTEDRLR DVIYASDEEL DQSSAKEITQ ERKLDFKKTE ARFFHQAIVS TYINYLSRYE DLSNQEIKTC LSYFHRLFVV RKDFTGLYRL DFMQLLQKLR NHLQRGSSLR LQVEEFIYYF MKKFKTAFER FPMPIEVLFP RFEDNECKVY LATGEVYEKE ETTSTSRSPR LAKDLEFVRD FGLDDQIKIL VSQLHVQEKQ SLLKWLIQEL ERIINDRILN SDSIAELNAS NQHRRLFINN GYLRFLLRII GFDLPYTMEE VPELANTVDM EHLTKVTELI KKWDSSQPVI FEDDKVPSYF VRTREAGYDE DQYNENDQEY DFDDDSIAFE TEANPNSNRN HVSELDHLEE LERQLSSNGS RVNSKERNGT KGKARKKSKE KKRPEPKKVR GLKRRRIPKD LLDDDDSQHV VKSAEFVHDS DDESDDEKDK AFFEREEKMR SLLNDMGGIA TSEQLKEIQK VWKNLETGGN NKVASTVAKA VKEVGLFVED SDNDDEVEEE SRNSAPVNEE ADRTIFESGE VDTQQDLSDD TSNTSDMESE TATTKRSFVE DQEEISHVQS KRKRLVISDD EEE // ID C5DK73_LACTC Unreviewed; 1214 AA. AC C5DK73; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 13-NOV-2013, entry version 20. DE SubName: Full=KLTH0F02310p; GN OrderedLocusNames=KLTH0F02310g; OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284) OS (Yeast) (Kluyveromyces thermotolerans). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Lachancea. OX NCBI_TaxID=559295; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284; RX PubMed=19525356; DOI=10.1101/gr.091546.109; RG The Genolevures Consortium; RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., RA Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., RA Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., RA Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., RA Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., RA Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., RA Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., RA Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., RA Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., RA Straub M.-L., Talla E.; RT "Comparative genomics of protoploid Saccharomycetaceae."; RL Genome Res. 19:1696-1709(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CU928170; CAR23874.1; -; Genomic_DNA. DR RefSeq; XP_002554311.1; XM_002554265.1. DR STRING; 559295.KLTH0F02310g; -. DR GeneID; 8292503; -. DR KEGG; lth:KLTH0F02310g; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1214 AA; 136931 MW; 3D81E6A860C18889 CRC64; MSTLGSSQIP EATGEFGSPQ RSAEDGQPVV DNSSQILKAR IALLATAIGG PDHSSEVDPP PYVIGDDCLA CLKDLKRWFK LVDDKQSRWD VAAAAAQYNI LTEDLLPILI NWDKAHCDAI KKAKKKGGTP EDYLGNKSYH HKIALNALQL MVLMTWPLIL TDQSTQNQVA HYSELKKSQV KYKKAILSVE NGRVLRSAIR LAVEVIKTEK RLRTPKDNVV LRLVLNFFRN IVAIEPSDLT ISSKKSLSKG INSTDMLPPS VSRDDISLSA VVGAFQTNKV FKFLLTLSSS INQEFDAAFI NVPLLELIFF LIKNASHSTF FPAGGKTSSK PNQKNEGLGQ TQVGSELSRL LKKEREMKKT VVRNTSTRHS RFGSLLSIQT SEHQRLTVSG GQNILDGDFA LQKMDSRKKW NKRSVMKDEH VEGLASNFLN FNEEARYWDN ATALVLKEFV DDFIEVGFNS LLRSVTDYFT TEEDKMVVVH QIQYLLFYSW FLKYQRLAKQ SDPKLNFQPV MFALRDTACI LVSQILRKAV EQKVWAVVHA GMIAFNEIMS TLATMGPEDE DIAQYVKGQI LQEERIKLLS SLPRTASNHS TSYIRSCVSL VHTLLRMLES DSIESKEPQE SNKNAKGRDG TFSLIEAERI AEEEGIEIEE ALEIMEQRFR KASLDYNKVQ RAFSVETTVK TYISFLQRFR DLEDGDIKKA IQFLYRVFAG VKEESLLYRI DFMILLKDLL GPTGLSMASR SRKHVVKFAD FYMARFKERL KASPSWFVSI LFPTIHDREA GHYQKYGEKL MANQNQIVLP SSKFIEAEEL IGLSASALLD FKFGVLVSSL IDNEKRECVE ALKQALTRTC NVLKSWLLNE VSRGDEFGHT SKEFFEPEDA FVKRSTYRDP DFRALLQLCG YEVPQSVKGK CVLIPSTPIP EIESSITLLV KYLTNAFDTP NGLPSSSYLT RPNTQGAEDD SYYFTNDGIQ TEAEQDDTGN QDQYFKALES DALTNNLHST RGVALKKRKK ATRKDNAKPK TNKQNSNPRK SEREPSTNSE PSNKRQNITS AEYISDSDDS SDESMHSIFY ENEMYMRFLL DKHGGLLPPD KFALFSVFSN ERIKNGGLTT NDYSSLFGGP IPSLEGLKRS EGLEAPQTVS GKINNDLHDR EVPRLLANQQ KHLHGSSPTG SEVIQPLSNH PLLSDASDKD DEEVSKTPAQ TRKRQRVMFE DDDE // ID C5DYY5_ZYGRC Unreviewed; 1208 AA. AC C5DYY5; DT 22-SEP-2009, integrated into UniProtKB/TrEMBL. DT 22-SEP-2009, sequence version 1. DT 13-NOV-2013, entry version 22. DE SubName: Full=ZYRO0F16742p; GN OrderedLocusNames=ZYRO0F16742g; OS Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / OS NCYC 568 / NRRL Y-229) (Candida mogii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; OC Zygosaccharomyces. OX NCBI_TaxID=559307; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229; RX PubMed=19525356; DOI=10.1101/gr.091546.109; RG The Genolevures Consortium; RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V., RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., RA Jubin C., Poulain J., Barbe V., Segurens B., Artiguenave F., RA Anthouard V., Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., RA Durrens P., Jean G., Marck C., Martin T., Nikolski M., Rolland T., RA Seret M.-L., Casaregola S., Despons L., Fairhead C., Fischer G., RA Lafontaine I., Leh V., Lemaire M., de Montigny J., Neuveglise C., RA Thierry A., Blanc-Lenfle I., Bleykasten C., Diffels J., Fritsch E., RA Frangeul L., Goeffon A., Jauniaux N., Kachouri-Lafond R., Payen C., RA Potier S., Pribylova L., Ozanne C., Richard G.-F., Sacerdot C., RA Straub M.-L., Talla E.; RT "Comparative genomics of protoploid Saccharomycetaceae."; RL Genome Res. 19:1696-1709(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CU928178; CAR28996.1; -; Genomic_DNA. DR RefSeq; XP_002497929.1; XM_002497884.1. DR STRING; 559307.ZYRO0F16742g; -. DR GeneID; 8205701; -. DR KEGG; zro:ZYRO0F16742g; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1208 AA; 137326 MW; DC52BD54C199EBC2 CRC64; MVDPNDLSTT VLKARIALLA TAIGGPDYTS NLDPPPYKLG DDCLACLKDL KRWFRLVDEN QNRWDVAIAA AEYRILQDDL IPILIDWENK CSLAHKLNKD SYNKEYHDNI ALLCVQLIVI MTCPQVLTDQ STARQVAVYS ELKKRQLEYK RDILMAERGK VLRAIVRLAS KVIKIDRIDR TPRDNVVLRL IINLFRNVVA IEPGELNITK KKQISTKGIN SVDTLPPGVS MDDISLNTVI AAFQKNKVLG LVLTLASSMS VEFEQDFINT PLMELMFYLT KDIPPESLVG SDKRQESHND SDRVSSTGAE LLNLLDKENN LKKNVIKNTS TRHSRFGALL SIQTPDSGRL TVSGGGQNLL DDSTALNKLD SRKKWNKRSV QHRDDIVAEG LPNSLLNSGT KSGFSLDSTM MKFAHFIDDF IDSSFNTLLH SVTNQYTGDQ DQMTTLEKTE YLLFFSWFVK YQREKCNKDL AADISSVDSA LQETSFILVS TILRTGYELK NWAAVHAGMI AFNELLLLIS SIQDPYNSDE VEFIVGKLFS DDRIQLLTSL PKTAFRYSLQ YMKSCVELVH TVLETLEQYT KDNSLTVTRK TKSTKRKEIT EEQVTVLMDS QGIGRDEALD LLNPSFKKME FNFMKVLKKF CVESIVDTYI NYLQRFRELN DTEIKKAIYF LHRVFVQASE QSILFRLDLI MLLKDMLAPD GVSRKSRVRK HIEQFSNYFL YKLKKRLKSS PSWYIGLLFP LLYGSEVGYF QKYGEVKPHK ENNYHAVPPS RFKNIEDEEQ LPESVLKDMK FGILVSTLID DGKEELLISL ISHMQVALDR FKSWLSVNVQ HERETENSPD EILGSENFNG SKPFIFDKDF RTLLDLIGYS LPLNVEEQCK LPGNVEIDSL QDSLELVKKH LATPFQTPNG LPSSSYLLRP KLNASGSNAE DDGWHGDDEY DYEEPGIVPD GQQLFVTDDD AYFEELEKDM GDKLSGKETD KDKGIAKSKK KPKAKTKRSR KQKDNSSLPL HDIGEQPEKT KQRKDVLSKD FISDSEEEED NINPLFFENE MYMRWLLDKH RGQLPEERYA LFGKFSAERI ANNGSLVNDY SALFGGAVPD LEDLRSSETT SDSPDRTLIS LSRRVAAEIE KASEEPEPQN THETDLSDSE VSMDDFPVST SNADARTSPL TKRPTTDLSS SEDDNSTGHA NLSRKKRKVL FADDEDDD // ID C5FJ74_ARTOC Unreviewed; 1167 AA. AC C5FJ74; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 16-APR-2014, entry version 21. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=MCYG_02314; OS Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum OS canis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Arthroderma. OX NCBI_TaxID=554155; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4605 / CBS 113480; RX PubMed=22951933; DOI=10.1128/mBio.00259-12; RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W., RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E., RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I., RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., RA Summerbell R.C., Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., RA White T.C.; RT "Comparative genome analysis of Trichophyton rubrum and related RT dermatophytes reveals candidate genes involved in infection."; RL MBio 3:E259-E259(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS995702; EEQ29495.1; -; Genomic_DNA. DR RefSeq; XP_002849380.1; XM_002849334.1. DR GeneID; 9226372; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1167 AA; 132361 MW; 92506CF41FF59D61 CRC64; MDAEPLVAQA GDQVVDPEVR SFIYSLVTAL GGSANDEAGR YTLGDDALGC LRDLKKWLRF YDEKLNRLDV ARCLAESNLV NGDLIPILAL WDEVKPTDKY KSRITLACLE LLVPLTWPVE IHSEMTINHH RHTPYLQRAQ ISYKRGILGH PSNSILRSII RIGLPSITTP RPERSSRDEG ILKLVLYLFR NVTIINATPN LLVEGDEDET SRSMTINAFH NQDVFAMLLT LCSNIEEEFT FQDVILLEIL FHLIKGVEVK QLFMDNSQRS ATRTDELKGL MDAESSLTRD RSKHAPTRHG RFGTMIWVKR QDEKVSSVSG QDVLLNDQAA FDKMDKTKRW NKPRGRRPVM DETSNNFNMQ VHLTSSALHH LRLFVEEFLD SGFNPLMTSI RKAMERESDR LTESSSRHFF FVGSWFLNAE RARRAQQEEA RRKATGSAKE IEPDSFALVA SVLNQETFIA LNRFMQTSLD NKEWQDLNAG MLSFTQTLLT VQEMAKSALE EDQEIAENIQ SRIFYEESTH DRILSTLRGY KGQGFWYLDA CTELAHVFLR MLEQYSKQNV DMQVRSKRIS RRKKKVQNQS QENMGEEDDG FDNSEDEEAA DRAEAVRSVA ERSFDFKRFC SKFCTQSSVN TFVALASYYR DLDTEQLKRA HRFFYRVAFK QELSVLLFRL DIIALFTRMI KGPEGLASSN PVFGEWEELV RQILKKLFRK IDERPQLITE LLFSKIPATV HYLEYGHDKQ TLTVTSRPAA ELEIKPNATR TTDENIRIVV SSLVADGSED LVRWLCEILD NALKDRKSWE LADLARGTQD AADIVDIAPS TPAIEVSGPD EKCKTAMFKN GRLRLLFTLA GLVLAGEDVL GTPWSIPGSI SSAVLEETHN SIQQHCDNPA PEIDGVDPHT LIRRKRIAGT ATNNDDSTAH VNFGSDSEGE DLGLDQVLFP PNLRSKSKAL KELKQKRRKG KKGDEDEDNH LDEEALNARR LAREQNALER QKKIKSSLFV NASDDETDDE ADQEFFAREA ERRKRQAQRT EDAMALDILG ERTGKAKGKR KQAISSDSDE EDEISSQRKR ARSQNPASGS DVEELGATSQ LRAQTPPTST EDDLIFDIGE KSPAPTFQWS STAADIPAKS IGEQDDDNDE DDDEPITMTR SRRPKMMAGF MVDSDSE // ID C5GWU0_AJEDR Unreviewed; 1137 AA. AC C5GWU0; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 16-APR-2014, entry version 13. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=BDCG_08692; OS Ajellomyces dermatitidis (strain ER-3 / ATCC MYA-2586) (Blastomyces OS dermatitidis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=559297; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ER-3 / ATCC MYA-2586; RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Klein B., Goldman B., RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., RA Berlin A.M., Heiman D.I., Hepburn T.A., Saif S., Shea T.D., Shenoy N., RA Sykes S., Galagan J.E., Nusbaum C., Birren B.W.; RT "The genome sequence of Blastomyces dermatitidis strain ER-3."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EQ999984; EEQ85423.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1137 AA; 130038 MW; B98D2B12AC36102E CRC64; MESESVQPVQ VVDPEVRAYV YSLITALGGS GSSDTGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAEANLQSQV LYKRGILGND TTAILRTIIR IALPSMTTPR SDRSSRDEGI LKLMLYLFRN LAIITPSPHL AREGDEEEAS KSATINAFQE QDVFALLLTM CSNMGEDFVF QDVVILEILF HIVKGVDIEK LFMNDTQRSI AGTDDLEALL DKESHLKREY AKTAPTRHGR FGTMIWVKRD DEKVSTVSGQ DVLKDDWTTM LKMDKTKKWN RPKHRRGGVD MSVNNFNVPS PLTPSATKNL RTFVEEFLDS GFNPLFSHLR KAIEREADRV TESTPRQFFY VISWFLEAER VRRTRQQELR QQNPNPARDI EPDSFQLVAS VLNQETFIAL NRHMQNCLDF KDWQDLNASM RCFTQILLTV QQMFHSDISE DQDIAENILS RIFYEETTHD RILTILRGYE SQGFWYLDAC TELAHVFLRL LEQYSKQNEH MQIRSRRRAR RKQRKEAVAN PENPETQNHD ESEAEDLAME DATRTIVERS FDFRRFAAKF CTQKSVNTFL ALTTHYRELN EEQLKRAHRF FYRVAFKQEL SVLLFRVDII SLFYRMIKGP GGLDSAKSVY AEWEELTRRV IRKLIKKLEQ RPELITEMLF SKINATVFYL EYGHERQTVS NSKPAAELEV KPGAATTLDS RLGIVVAALH LEGKENLVQW LVKTLDTAVN ERRCWELEAE SRQTESGGEH PPSPPSIAVI PLDDACRTAM FKNGRFRLLM TLAGFERLGV EDTLDSSWII PSSLSAKTLE ETQKSVEKHS ENPPTEFDGL EPRDLLRRKR DVDTTMPSHG RPQGEVDFGN DSEGEDDIDG ILFPPNLRIR TGTLDELKKK RLRRGKKNKE DGDGPDEAAL EARRLARQAN ALERQRKIKS SLYINASDEE SDEEADREFF AREEERRKNQ ARRIKQALLS GTAGGDKATG QKSSSKGRKR KSTANGDENN KRQRSDPLLD SDDEDNAINI DNPEDDDDED VMMATQETPS SSSETESISM AQPERRSENT TPPTSTERNP IFGMNDDDYF DNPFYFASLA DKDKTGGDKG VGSDGREEEE QVKMPARQRR MLGAFIIDSD SESEVGE // ID C5K392_AJEDS Unreviewed; 1126 AA. AC C5K392; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 16-APR-2014, entry version 13. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=BDBG_09267; OS Ajellomyces dermatitidis (strain SLH14081) (Blastomyces dermatitidis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=559298; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SLH14081; RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Klein B., Goldman B., RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., RA Berlin A.M., Heiman D.I., Hepburn T.A., Saif S., Shea T.D., Shenoy N., RA Sykes S., Galagan J.E., Nusbaum C., Birren B.W.; RT "The genome sequence of Blastomyces dermatitidis strain SLH14081."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG657485; EEQ76037.1; -; Genomic_DNA. DR RefSeq; XP_002620339.1; XM_002620293.1. DR GeneID; 8501026; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1126 AA; 128717 MW; 876BCE79441C5C6E CRC64; MESESVQPVQ VVDPEVRAYV YSLITALGGS GSSDIGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAEANLQSQV LYKRGILGND TTAILRTIIR IALPSMTTPR SDRSSRDEGI LKLMLYLFRN LAIITPSPHL AREGDEEEAS KSATINAFQE QDVFALLLTM CSNMGEDFVF QDVVILEILF HIVKGVDIEK LFMNDTQRSI AGTDDLEALL DKESHLKREY AKTAPTRHGR FGTMIWVKRD DEKVSTVSGQ DVLKDDWTTM LKMDKTKKWN RPKHRRGGVD MSVNNFNVPS PLTPSATKNL RTFVEEFLDS GFNPLFSHLR KAIEREADRV TESTPRQFFY VISWFLEAER VRRTRQQELR QQNPNPARDI EPDSFQLVAS VLNQETFIAL NRHMQNCLDF KDWQDLNAIQ QMFHSDISED QDIAENILSR IFYEETTHDR ILTILRGYES QGFWYLDACT ELAHVFLRLL EQYSKQNEHM QIRSRRRARR KQRKEAVANP ENPETQNHDE SEAEDLAMED ATRTIVERSF DFRRFAAKFC TQKSVNTFLA LTTHYRELNE EQLKRAHRFF YRVAFKQELS VLLFRVDIIS LFYRMIKGPG GLDSAKSVYA EWEELTRRVI RKLIKKLEQR PELITEMLFS KINATVFYLE YGHERQTVSN SKPAAELEVK PGAATTLDSR LGIVVAALHL EGKENLVQWL VKTLDTAVNE RRCWELEAES RQTESGGEHP PSPPSIAVIP LDDACRTALF KNGRLRLLMT LAGFERLGVE DTLDSSWIIP SSLSAKTLEE TQKSVEKHSE NPPTEFDGLE PRDLLRRKRD VDTTMPSHGR PQGEVDFGND SEGEDDIDGI LFPPNLRIRT GTLDELKKKR LRRGKKNKED GDGPDEAALE ARRLARQANA LERQRKIKSS LYINASDEES DEEADREFFA REEERRKNQA RRIKQALLSG TAGGDKATGQ KSSSKGRKRK STANGDENNK RQRSDPLLDS DDEDNAINID NPEDDDDEDV MMATQETPSS SSETESISMA QPERRSENTT PPTSTERNPI FGMNDDDYFD NPFYFASLAD KDKTGGDKGV GSDGREEEEQ VKMPARQRRM LGAFIIDSDS ESEVGE // ID C5LW36_PERM5 Unreviewed; 518 AA. AC C5LW36; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 18-SEP-2013, entry version 21. DE SubName: Full=Calmodulin, putative; GN ORFNames=Pmar_PMAR019754; OS Perkinsus marinus (strain ATCC 50983 / TXsc). OC Eukaryota; Alveolata; Perkinsea; Perkinsida; Perkinsidae; Perkinsus. OX NCBI_TaxID=423536; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 50983 / TXsc; RA El-Sayed N., Caler E., Inman J., Amedeo P., Hass B., Wortman J.; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG686046; EEQ99106.1; -; Genomic_DNA. DR RefSeq; XP_002766389.1; XM_002766343.1. DR ProteinModelPortal; C5LW36; -. DR GeneID; 9044583; -. DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro. DR Gene3D; 1.10.238.10; -; 1. DR InterPro; IPR011992; EF-hand-dom_pair. DR InterPro; IPR018247; EF_Hand_1_Ca_BS. DR InterPro; IPR002048; EF_hand_dom. DR InterPro; IPR006906; Timeless. DR Pfam; PF13499; EF-hand_7; 1. DR Pfam; PF04821; TIMELESS; 1. DR SMART; SM00054; EFh; 2. DR PROSITE; PS00018; EF_HAND_1; 2. DR PROSITE; PS50222; EF_HAND_2; 2. PE 4: Predicted; KW Calcium; Complete proteome. SQ SEQUENCE 518 AA; 58388 MW; BF9D91292CD51C05 CRC64; MSSYPGPDDE EEDTEVVDLE DTDEVDEEGY VVDVDDEEDK SFEEELHCSV EGLGCWHTID NEQIYLAPGD AFECIRDLLR AFREEVGASR RVHRLLGKWG VVEKKLVPML ISHRDDLDDK CFQILRLMVI LTMPVNRDTP ELDTHLQYLQ GYKAAIGLNE DVLTIFMTIL DQCIGVSLTQ GQYSSSSSST QEVGDATKRL RAQQQELVFT LVRNLLEIPD PRPGDPGFSP AHRDLQMTML QELYESGFLD FAVLVMEDAL NGPTPTINRN KQLLWLYFEI LYHACAKIRP VDLITVDARF KPDLSALINR SILTYAASLP ILTRHNRFGK RVAVNMPDDG PSSTKQLIAG RQRHYRNKLV DEAPNVFQDR TFTDVDVGSK VPVVVGDAPA GLLQEVISAD GGVSMINLAV WEKFLKSFAS FIVDMIDRVF AGIMAXXHVI IVLCRYIQKD VCWAAFRVFD RDGNGKISRE ELQDVLGNDD VRTALGSDLV TQMINEVDLN GDGEIDFDEF MQMMQKST // ID C5M8J4_CANTT Unreviewed; 1297 AA. AC C5M8J4; DT 28-JUL-2009, integrated into UniProtKB/TrEMBL. DT 28-JUL-2009, sequence version 1. DT 13-NOV-2013, entry version 13. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=CTRG_02716; OS Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=294747; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-3404 / T1; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG692397; EER33898.1; -; Genomic_DNA. DR RefSeq; XP_002548419.1; XM_002548373.1. DR GeneID; 8302105; -. DR KEGG; ctp:CTRG_02716; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1297 AA; 148761 MW; 2B63D6DC9E8F0A48 CRC64; MSSSGPESEF EEYSDGGELD GFIDYSDEEN QQENPQQVEL QLNSDGEVEE EEEDRIRALT TTLKPNETQA QKLLKAHISV LVSALGGPDH TSDIQPPPYK LGHDALACLK DIKRWIKAVD EKKNNYEVAL ACAETGLVPN DLLVILCQWE DKMQKKQAIV NKTTTEKTML ACLELLVLLT WPVEFSKELS ESQKLLYSNI KKVHVTYKKQ ILTYNNGQLL KAVIRLVLPT IAKSRIDREP RDNQIMKLVL YLIRNILAIE PANQSISGKS SDKGSTALAS DLPVGISLDD ISISHILTVF KKNKVLMLLL TISGSLGVEF DREMFGELCL ECIYLMVKGM SASDVLVKKE FPKLSTPSTT TSTTATGTDF VPDSINASQP LQSVTTTSGL QLQDLLSTES KRKKIQTSTI SSRHGRFGSL LSIRSSDSNS FVVSGQEALI DANSSMAKLD KSKKWKSVTY FRYDSDDYVK TTTPVYLNVM GQSIMNTFIE QFLSGGCFNN LIECMGSRLT SQSDLAMIDE LFVASYFFTI AWFLSYQREK IALNPDDHEL NYGSVGAALS EVNFVLIISY FRDSFTLKRW NSLHVAMICF RELLQISNSI FGKRKNINSK DIENEDDVSQ HEVDRELAEG IIRKLFSFRD FMNIIIQIPQ TAAKHSPDYL RVSVSVVHIL LKAFESFANE DVQLYIQSKR RQKRKNRSRI NNLDKATEDR LRDVIYASDE ELDESSAKEI TQERKLDFSK TEARFFHQAI VTTYIKYLSR FEDLSDQEIK ICLSYFHRLF VVRKDYTGLY RMDFMQVLHR LRNFLQRGSS IRLRVEEFIY YFMKKFKLAL ERFPLPIEVL FPRFEDQETR VYLATGELYE KQEESSSTRV PRLAKELEFV REFTLDEKIK ILVSQLHIQE KQMLLNWLIS ELERIINDRI LDSEAIIELN GTNQFRRLFI NNGYLRLLLK LIGFDLPFTM EENPELPTSV EIGYLTKIAD LIKKWNSGQP VIFEDDKSPS FFLRTRESGY DEDDYDDVEY DGKYNPDDES IAFETQANPN STNFAVSQLD QLDELERQLM LSQRNKEHRS DPDHVRGKAR RKKKKRPDDN SQKKSKSKTS HKDPNHIRRR RIPKDLLDDD LHVIKSAEFI NESDDESDDE KDKEFFEREE RMRKLVDDIG GIATPAQLLE IQKLWKNLEI KGGDKTAVSV AKAVKEVGLF VAESDNEDGP QEETHINTPE QSQVSLPSLS PIPQEVVDAD AEEEEEGQIS SHTSDTSDVE LEVESSKRKL DDDVEETLTV QTTKRKRMII TDDEDDE // ID C5P3U5_COCP7 Unreviewed; 1171 AA. AC C5P3U5; DT 01-SEP-2009, integrated into UniProtKB/TrEMBL. DT 01-SEP-2009, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Timeless protein; GN ORFNames=CPC735_062360; OS Coccidioides posadasii (strain C735) (Valley fever fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Coccidioides. OX NCBI_TaxID=222929; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C735; RX PubMed=19717792; DOI=10.1101/gr.087551.108; RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., RA Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., RA Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., RA Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J., RA Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.; RT "Comparative genomic analyses of the human fungal pathogens RT Coccidioides and their relatives."; RL Genome Res. 19:1722-1731(2009). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACFW01000015; EER28363.1; -; Genomic_DNA. DR RefSeq; XP_003070508.1; XM_003070462.1. DR UniGene; Cpo.465; -. DR STRING; 222929.C5P3U5; -. DR GeneID; 9696003; -. DR KEGG; cpw:CPC735_062360; -. DR eggNOG; NOG328380; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1171 AA; 133634 MW; 014E75499F01D287 CRC64; MEIEPPQAVE VVDPEVRSYV YSLVTALGGT AGDETGQYVL GDDALGCLRD LKKWLRFYDE KLNRMDVARC LAECKLVNGD LVPIISLYGD AEQSDKHKAR IMLACLELLV PLTWPVEVHG QMTFNHHRHT PYLQYSQVEY KRGILGFAPS PILRALIRVG LPSMAIPRSE RSTRDEGIIR LMLYFFRNIA VITSPPNLPI DSDDDKATRS ATINAFQQQD VFALLLTMCS NMGNDFTFQD VIILEILFNL VKGVDVDQLF KLNERAGTIK TDDLQDILQK EDELNREHSK NAPTRHGRFG TMIWFKRDDE KLSTVSGQDV LKGDRATFLK MDKTKKWNKP KFKREVVDPS SNNFNLKVRL TSSATKHLRT FVEEFLDSGF NPLFTHLRKA IEREADRVTE STSRQFWYAV SWFLHAERAR RGHQKKTRQR SKGTSREIEP DSFSLVASVL NQETFVGLNR FMQHSIDFKD WQDLTAGMKC LTQILLTVQE MAISPLEEDQ EIAENIQSRI FYEETTHDRV LSILRNHRDQ GFWYLDACTE LAHVFLRMLE QYSKQNVDMQ VRSRRRARRK QAQAAVPNQN ETEAGGEHDS ETEDIAEAHR TVTERSFDFK RFSVRFCTQK SVDTFVALTK YYRELDSEQL KRAHRFFYRV AFKQDMSVLL FRVDIISLLF KMIKGPEGLD PSKPPFKDWE ELIRQIFKKL VRKLGERPEL VVELLFSKIN ATVFYLEYGH EKQTMSESRP ATELELKPGS ASTLDEKTRI VVSALIQEGK KPLVKWLSQV LGSAASERLS WEMEAEAMAT SSPEEQSDGS KAPSIAVLPE DDGCRTAMFR NARLRLLMRL AGLERLDEDV LGASWMIPSS VPSSNLKEYH ELIEKHCESP AEDIDGVDPR DLMRRKRTAA DTNSSRHEFT ENVNFGSDSE GEDDGVLFPP NLPERSKALK TLKQRRRRRR RSDDAEESGP DEAVLEARRT AREKNALERQ RKIKSDLYVH ASDDESDEEA DIEFFAKEEM RRQAQARRVA EALETGMPEN NTTKKKSKAS AGRKRKVKPV LELDDDDSEA SPPKRRRSDE VIESDSDGEL MVGIGSTSPR RSQTPPTSAD NIFGSEKSPS PMFPWSVGVD QMIAKLQGKE EASADNGESN EDEGEDVLSG TGRTRRRRTM GGFVIGSDSD S // ID C5YVZ1_SORBI Unreviewed; 1309 AA. AC C5YVZ1; DT 01-SEP-2009, integrated into UniProtKB/TrEMBL. DT 01-SEP-2009, sequence version 1. DT 14-MAY-2014, entry version 25. DE SubName: Full=Putative uncharacterized protein Sb09g028970; GN Name=Sb09g028970; ORFNames=SORBIDRAFT_09g028970; OS Sorghum bicolor (Sorghum) (Sorghum vulgare). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; OC PACMAD clade; Panicoideae; Andropogoneae; Sorghum. OX NCBI_TaxID=4558; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. BTx623; RX PubMed=19189423; DOI=10.1038/nature07723; RA Paterson A.H., Bowers J.E., Bruggmann R., Dubchak I., Grimwood J., RA Gundlach H., Haberer G., Hellsten U., Mitros T., Poliakov A., RA Schmutz J., Spannagl M., Tang H., Wang X., Wicker T., Bharti A.K., RA Chapman J., Feltus F.A., Gowik U., Grigoriev I.V., Lyons E., RA Maher C.A., Martis M., Narechania A., Otillar R.P., Penning B.W., RA Salamov A.A., Wang Y., Zhang L., Carpita N.C., Freeling M., RA Gingle A.R., Hash C.T., Keller B., Klein P., Kresovich S., RA McCann M.C., Ming R., Peterson D.G., Mehboob-ur-Rahman M., Ware D., RA Westhoff P., Mayer K.F.X., Messing J., Rokhsar D.S.; RT "The Sorghum bicolor genome and the diversification of grasses."; RL Nature 457:551-556(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000768; EES19969.1; -; Genomic_DNA. DR RefSeq; XP_002441539.1; XM_002441494.1. DR UniGene; Sbi.10518; -. DR STRING; 4558.Sb09g028970.1; -. DR EnsemblPlants; Sb09g028970.1; Sb09g028970.1; Sb09g028970. DR GeneID; 8064694; -. DR KEGG; sbi:SORBI_09g028970; -. DR Gramene; C5YVZ1; -. DR eggNOG; NOG302007; -. DR HOGENOM; HOG000084060; -. DR KO; K03155; -. DR OMA; HKQPKSD; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1309 AA; 148228 MW; BA2C0727F62650E4 CRC64; MDSAVLSLTC AGLGASQEDE DGAVIGYAKS DHCLDNLKDL QRFLRRDDPQ RREVFKQVCK WKIASRDLVP IIENYQNDRN LVITAVKVLV FLTMPVESSS DDVAQQIEYL WDLKAALTRN VAVTVIVSLL EDPLDRLESL VQTHFPKGPH YELLPEYIWK SKVNMTNLWQ ALGDCTKLFF NPVVFVYQDI SKTKLIVFNK GSIFFFTSFN PYFKHIVFVD SIWQSDDKDD KFQTLFSEDD WKLVQLVLTL FRNVLAIQEI TLTQKASGEA THLLFLADSF LELMFQENVM DIILVLTQHI DEPSGYLKEE NLLLMEIYHY LFLGRDPGLI ARASNKGSKD GSKSLCKGNP SSSSANSLLK IRNVQRGPQK RIAWDNELLY IPKEGITEML RSFMDQFLSG AYNILMQSVC DDIMDEHHSI EKSDIITFFK VARFVLAFQH EKASNDQKSV KGIQPSEVSP SNEHDDNLPF HGDICGPVAA TLNEDMFNIV ISRWRETYEG LKETNDYKTL SAAGSLMKNM IDMIYLVLKV LPEDSRESQT ARVLLYKLFY DQTENGLTQF LLNLFRSFDS HKQPKRTYNK LLDILDWKFV ILRTHRLDFH ALNAFNGIMQ FGCSCSQSDL VDLLETIHIM LQLMEKLQAR GTLRVAKKTK KVRRKKATNG KNENSEPKVE NVEPNDAHPT DETKCSPESL PDLRIEGPAS EPSPSEPGKV DTSGAPVPDI LVDTAVNMES TAHAEGGPSC TDGGVMKNLI DEEGETSDSS VDHQPATSEV DFNVSRLISS LANNSVVQNI CWLLKHYKSN SYRTNHYIIC MLRRFCEDLE LSPMLYQLSL LTTFYDILAE EKSSSSKEYT NIVNFLSKVV RKMLRSIKKQ PLLFVDILFW KTRKECHCID ADLLLNELKK DAGNKDGEIG SSKGWRGPVN IADSLGDDEV DLVIPQAPYD ADKDGDLSAD EHGDDFRKSS TTYKRSRFMS LSDSDAEENE RNHVSRDSVP KVPKRRGRSL FTEEQERLIR DLYEKYKDDR KCSHLIADAL DSSGKITSAQ VSRKLTQLGL RNVTRRKKGA DESLLTGDRA TEPQNNSLDD LNSMLAEHNH GPKSKSSRAR RKRLNVSSDG HDDTSHGRSS DEETLQVLKS RTKNKKVPLV DSSLSAPQHQ EAQHDPDSDD ATIGSMIRSR KKKRLSTSDF EGNVQNHQES SDNTNTKDCS PTISQHEKIL LDTYSDDETI GSIFRSGKKK RDVSVNHGSD PVHNSGNNVE AELLDDFEVE LDNHENTDQR ITDDGNMTES GDTTNSDANR RAGLKRRHRL VIDDDDEDD // ID C6H514_AJECH Unreviewed; 109 AA. AC C6H514; DT 01-SEP-2009, integrated into UniProtKB/TrEMBL. DT 01-SEP-2009, sequence version 1. DT 16-APR-2014, entry version 12. DE SubName: Full=Topoisomerase I; GN ORFNames=HCDG_00335; OS Ajellomyces capsulatus (strain H143) (Darling's disease fungus) OS (Histoplasma capsulatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=544712; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H143; RA Champion M., Cuomo C.A., Ma L.-J., Henn M.R., Sil A., Goldman B., RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., RA Berlin A.M., Borenstein D., Chen Z., Engels R., Freedman E., RA Gellesch M., Goldberg J., Griggs A., Gujja S., Heiman D.I., RA Hepburn T.A., Howarth C., Jen D., Larson L., Lewis B., Mehta T., RA Park D., Pearson M., Roberts A., Saif S., Shea T.D., Shenoy N., RA Sisk P., Stolte C., Sykes S., Walk T., White J., Yandava C., Klein B., RA McEwen J.G., Puccia R., Goldman G.H., Felipe M.S., Nino-Vega G., RA San-Blas G., Taylor J.W., Mendoza L., Galagan J.E., Nusbaum C., RA Birren B.W.; RT "The genome sequence of Ajellomyces capsulatus strain H143."; RL Submitted (MAY-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG692419; EER44756.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 109 AA; 11903 MW; EC6F53842C19C0F7 CRC64; MELESIQSGQ VVDPEVRAYV YNLVSALGGS GSSNTGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAETNLVNRD LIPILALLGD DIHDDNGIAC SSNMAARDP // ID C7GP90_YEAS2 Unreviewed; 1238 AA. AC C7GP90; DT 13-OCT-2009, integrated into UniProtKB/TrEMBL. DT 13-OCT-2009, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Tof1p; GN Name=TOF1; ORFNames=C1Q_02148; OS Saccharomyces cerevisiae (strain JAY291) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=574961; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JAY291; RX PubMed=19812109; DOI=10.1101/gr.091777.109; RA Argueso J.L., Carazzolle M.F., Mieczkowski P.A., Duarte F.M., RA Netto O.V.C., Missawa S.K., Galzerani F., Costa G.G.L., Vidal R.O., RA Noronha M.F., Dominska M., Andrietta M.G.S., Andrietta S.R., RA Cunha A.F., Gomes L.H., Tavares F.C.A., Alcarde A.R., Dietrich F.S., RA McCusker J.H., Petes T.D., Pereira G.A.G.; RT "Genome structure of a Saccharomyces cerevisiae strain widely used in RT bioethanol production."; RL Genome Res. 19:2258-2270(2009). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACFL01000082; EEU07375.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141190 MW; 5383B538F0176638 CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEDDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGVL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGI VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID C7YU38_NECH7 Unreviewed; 1133 AA. AC C7YU38; DT 13-OCT-2009, integrated into UniProtKB/TrEMBL. DT 13-OCT-2009, sequence version 1. DT 14-MAY-2014, entry version 19. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=NECHADRAFT_96220; OS Nectria haematococca (strain 77-13-4 / ATCC MYA-4622 / FGSC 9596 / OS MPVI) (Fusarium solani subsp. pisi). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae; OC Fusarium; Fusarium solani species complex. OX NCBI_TaxID=660122; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=77-13-4 / ATCC MYA-4622 / FGSC 9596 / MPVI; RX PubMed=19714214; DOI=10.1371/journal.pgen.1000618; RA Coleman J.J., Rounsley S.D., Rodriguez-Carres M., Kuo A., RA Wasmann C.C., Grimwood J., Schmutz J., Taga M., White G.J., Zhou S., RA Schwartz D.C., Freitag M., Ma L.-J., Danchin E.G.J., Henrissat B., RA Coutinho P.M., Nelson D.R., Straney D., Napoli C.A., Barker B.M., RA Gribskov M., Rep M., Kroken S., Molnar I., Rensing C., Kennell J.C., RA Zamora J., Farman M.L., Selker E.U., Salamov A., Shapiro H., RA Pangilinan J., Lindquist E., Lamers C., Grigoriev I.V., Geiser D.M., RA Covert S.F., Temporini E., VanEtten H.D.; RT "The genome of Nectria haematococca: contribution of supernumerary RT chromosomes to gene expansion."; RL PLoS Genet. 5:E1000618-E1000618(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG698900; EEU44734.1; -; Genomic_DNA. DR RefSeq; XP_003050447.1; XM_003050401.1. DR EnsemblFungi; NechaT96220; NechaP96220; NechaG96220. DR GeneID; 9674845; -. DR KEGG; nhe:NECHADRAFT_96220; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1133 AA; 129710 MW; 9D0B4B1CBC52785F CRC64; MELADGTIDI VHPEVRAHVN SLVSALGGIS ADDDGRYQLG DDALEVLRDL KRWIRFYDEK TNRMDVARCI YEANLIEGDL LPILATWPEN AMDSKFKSRM ALACFELMVP LTWPMERDRE RMTVNHHRHM PVLELAQVAY KRAVINFDGA RVLHTAVRVA LPSMAIPIGD RTQRDQGIIK LVLFFLRNIA MIEPPPDVKY DGDESQISRS ATIDAFSYQD IFMVLLTLAS NMGDDFRTED TSVMEVIYHL VKQVDIEKLF MNEQQLSKAK AGELAAMMNK ESSMLKAYNR KGPTRHNRFG TMIWVKREDG KMSSLSGQDA LADASMRNQK LDNTKTFRPP RRARKADKDE KDLGLPAKLN SRAYDQLRSF VEEFLDSGFN PLFQHIRKSI DREAPYLMQY HRRQFFYLVA WFLEAERMRR KARKQAGKKT DEDVSSFNLV AGVLNQEMFI TLNKALHESL DMKDWHELTA VMRCFTQILL TVQEMSDSGN EDNEEIAENV LSRLFYEEAT HDAIANIIRS YKDQGFNYLD AATELVHHFL RILEGYSKQN IDMQVRSRKR TRQKKKAAQD AAGVDNDNEE NDDSDNDAQT AERTTKERKF DFHRFASRFT PQGVVDTFVA FAKFYRDMND EQLKRIHRYF YRVAFKQEAS VMLFRVDIIN LFYNMIKGPA ALDKSSSMFK EWEELVKQIL RKCFKKIEQR PELIVEMLFS KLSGTAFFLE YGYERQTVTT ASKTKPGAEL VFKDDTEELD RQIAIVVGAM LDKNQGEHIA WLKKILGEAE TERRAWADAQ EAMPPVEPIQ DDEEEQPTVP EPKTAPMFYV RPDDNARRTT MFKNSYFRLL MNLSGLRLLS PASEETPESA WIIPGDLSAD GLKDAIHFIN QAEFSPPTFE EGVLAEHQLK RKPPPPKKAA FDDDDDGDLD GVPLFPAGGP TVRKVIDENG KDKPKKTRKK RRPLTDAEKE EAKRKKKKSA HEKLMNIKST EFVRDSDDEF TLEEDEAFFA REREIAAQAA HARATALGED AVVGKSGRGP ALRKREEDNE EETSQDDSDG EARKRRRVST ESESEDEDED EDEDEDEEMG GMDNAADKGA GKEAGKEVDK EADKADEDED VAPVVARRPR ARGGFLMDSD DDE // ID C8ZFW6_YEAS8 Unreviewed; 1238 AA. AC C8ZFW6; DT 03-NOV-2009, integrated into UniProtKB/TrEMBL. DT 03-NOV-2009, sequence version 1. DT 13-NOV-2013, entry version 8. DE SubName: Full=Tof1p; GN ORFNames=EC1118_1N9_0661g; OS Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse) OS (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=643680; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Lalvin EC1118 / Prise de mousse; RX PubMed=19805302; DOI=10.1073/pnas.0904673106; RA Novo M., Bigey F., Beyne E., Galeote V., Gavory F., Mallet S., RA Cambon B., Legras J.-L., Wincker P., Casaregola S., Dequin S.; RT "Eukaryote-to-eukaryote gene transfer events revealed by the genome RT sequence of the wine yeast Saccharomyces cerevisiae EC1118."; RL Proc. Natl. Acad. Sci. U.S.A. 106:16333-16338(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN393086; CAY82339.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141122 MW; C4B1D4AA14100D7F CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVQYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEDDI TKLIKEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KSLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGIL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID C9S978_VERA1 Unreviewed; 1413 AA. AC C9S978; DT 24-NOV-2009, integrated into UniProtKB/TrEMBL. DT 24-NOV-2009, sequence version 1. DT 16-APR-2014, entry version 18. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=VDBG_00233; OS Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) OS (Verticillium wilt of alfalfa) (Verticillium albo-atrum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Glomerellales; OC Plectosphaerellaceae; mitosporic Plectosphaerellaceae; Verticillium. OX NCBI_TaxID=526221; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VaMs.102 / ATCC MYA-4576 / FGSC 10136; RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137; RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E., RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J., RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., RA Santhanam P., Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., RA Inderbitzin P., Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., RA Galagan J., Cuomo C.A., Dobinson K.F., Ma L.-J.; RT "Comparative genomics yields insights into niche adaptation of plant RT vascular wilt pathogens."; RL PLoS Pathog. 7:E1002137-E1002137(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS985214; EEY14126.1; -; Genomic_DNA. DR RefSeq; XP_003008552.1; XM_003008506.1. DR GeneID; 9528660; -. DR KEGG; val:VDBG_00233; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1413 AA; 158066 MW; B7DF5BAB1CE14146 CRC64; MEMPDGTTDI VHPEVRAHIN SLVSALGGIS ADDDGRYNLG DDALEVLRDL KKWIRFYDEK TNRMDVARCI AEANLIDGDL LPILATWPEN STDNKFRSRI ALACFEIMVP LTWPVERDPE QTTVNHHRHM PALQLAQVGY KRSIINFDGA RILHAAARVA LPAMAAPIGE RTPRDQGIIK LVLFFLRNVA MIEPQPNVKY EGEESQISRS ATIDAFSYQD IFMVLLTIAS NMGEDFRTED VTIMEIIYHL VKRVDVKKLF MSEQQVNKAK ADELSVMMGK ENAMLKAQNR KGPTRHNRFG TVIWVKRADG KMTAVSGQEA LVDVASRRKK MDETKKFKPP RKARSKTDSH MKDLGELPKL DARAYSQLRS FVEEFLDAGF NPLFEHVRKS IDREASHVLS YHRRQFLYLV AWFLEAERTR KSSQRASAPK NSAEEVSSFN LVAAVLNQST FITLNRTMTQ AWEHKDWPEL TASMRCLTQI LLTVQEMSHS PNEDDQEIAE NTLSRLFYED AMHDLIANVV RQYKEQGFDY LDAATELTHH FLRILEAYSK QNVDMQVRSR RRTRRKKKAA KEASADGEGD EDEADDSGDD EKNAELTTKE RKFDFQRFSA RFTPQGVVDT FVAFTKFYKD LSDEQLKRAH RYFYRVAFKH DASVMLFRVD IVHLLHEMVK GPEPLDKASS MYKEWEELAK QILRKCFKKI DERPALLIEM LFSKISSTAH YLEYGFEKQT ISTSRPRPAA DLEFKYTEDR EQQMAIAVGV LLDKSQSDHI AWVKKILTNA EQERRALAAA EEILPSVEAT GDNDEPVDKP ADSFMPYTAR PDNDARQAAM FKNAHLRLLM RLAGLERHAP AIDESPDSLW VVPASATPDQ LRETLDLINK AEFSPPVFEE GVLAEHQLRR KTATRKKAQY DDDDGEGEDD DDDEDGDVAN AALFPAGGPT ERKVVNGKKK KKNKTRHVRK RRERDPDASG SDDDDEAARD RARARRERER AKLEKIKSQL YVAASDDETD DERDAAFFAR EEAQLQEKQH SVTVSQFLLA VSPARPPRRR GAHGPFHVVG SSGWSAVCAS YVLHDERLAR GLRSAAQHVA RLDDMGARQV ALLVCFGASL LDGESFGVEG AWGRGRGKGR PRIPATPREA KQEEVPVKAR RLSKRKLGAL CDERGDYCEE DGQKNGKGQS QENVANADVP EIDEPVAVRR RQEGDADERQ GCAVVLEEDA DVMVEETARP ELAADVRDHE DEQGSNDGQV EARSVGESLE HLDALLQIDE GDVEAKDVTG EAGDPSQPVA RVGDGKNPVE DERPDTDPTH EGEIVDTSGL HDVVDGAVEV RIGPDQIIGR GGEDDGPLLG GDVVVGVSNT VSAERGSVST GRGTSGAGSA APILVSSVLA ETMATVVDRA EACSGGLLWL MLG // ID D0MXM5_PHYIT Unreviewed; 979 AA. AC D0MXM5; DT 15-DEC-2009, integrated into UniProtKB/TrEMBL. DT 15-DEC-2009, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=PITG_02976; OS Phytophthora infestans (strain T30-4) (Potato late blight fungus). OC Eukaryota; Stramenopiles; Oomycetes; Peronosporales; Phytophthora. OX NCBI_TaxID=403677; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=T30-4; RX PubMed=19741609; DOI=10.1038/nature08358; RG The Broad Institute Genome Sequencing Platform; RA Haas B.J., Kamoun S., Zody M.C., Jiang R.H., Handsaker R.E., RA Cano L.M., Grabherr M., Kodira C.D., Raffaele S., Torto-Alalibo T., RA Bozkurt T.O., Ah-Fong A.M., Alvarado L., Anderson V.L., RA Armstrong M.R., Avrova A., Baxter L., Beynon J., Boevink P.C., RA Bollmann S.R., Bos J.I., Bulone V., Cai G., Cakir C., Carrington J.C., RA Chawner M., Conti L., Costanzo S., Ewan R., Fahlgren N., RA Fischbach M.A., Fugelstad J., Gilroy E.M., Gnerre S., Green P.J., RA Grenville-Briggs L.J., Griffith J., Grunwald N.J., Horn K., RA Horner N.R., Hu C.H., Huitema E., Jeong D.H., Jones A.M., Jones J.D., RA Jones R.W., Karlsson E.K., Kunjeti S.G., Lamour K., Liu Z., Ma L., RA Maclean D., Chibucos M.C., McDonald H., McWalters J., Meijer H.J., RA Morgan W., Morris P.F., Munro C.A., O'Neill K., Ospina-Giraldo M., RA Pinzon A., Pritchard L., Ramsahoye B., Ren Q., Restrepo S., Roy S., RA Sadanandom A., Savidor A., Schornack S., Schwartz D.C., Schumann U.D., RA Schwessinger B., Seyer L., Sharpe T., Silvar C., Song J., RA Studholme D.J., Sykes S., Thines M., van de Vondervoort P.J., RA Phuntumart V., Wawra S., Weide R., Win J., Young C., Zhou S., Fry W., RA Meyers B.C., van West P., Ristaino J., Govers F., Birch P.R., RA Whisson S.C., Judelson H.S., Nusbaum C.; RT "Genome sequence and analysis of the Irish potato famine pathogen RT Phytophthora infestans."; RL Nature 461:393-398(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS028120; EEY64388.1; -; Genomic_DNA. DR RefSeq; XP_002907824.1; XM_002907778.1. DR EnsemblProtists; PITG_02976T0; PITG_02976T0; PITG_02976. DR GeneID; 9477360; -. DR KEGG; pif:PITG_02976; -. DR HOGENOM; HOG000184057; -. DR KO; K03155; -. DR OMA; THANQNT; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 979 AA; 112655 MW; E4654D0DC5460013 CRC64; MAESTTRTGS DAERNEPTAS VERDEELEDF GVASSDEDTD ANDPHLDDAM MNELLLVCSN LGMLRVQNEG EPPVLMRGEN CAEWIHDLQR AVRRDHAKHK LVAKQLGKWK ILQKKLLPLL INHQHDWALV FSILKVLVML TMEPPKDSTN IAQQLKYLRQ YKHEFLRCDI IPIMMTILVE PLSRKGKRTA QDYLNMEIVL TLIRNLLAIP NEDPRFVTST TSYFSHLQED LICTLHEENV YEMILLFAQD IDSPENKEWN LMIMEMIDLT LDCSQPKSVV AFAKKRWAGE TTKCSGEQLA ASTSSRSSAD LSSGRTVAPA GGDLLTTLTN EKKASALHQS GSRRHSNFGG ILTMEVCDSI IGKSYSQLTN SLKTEFRRGS NKLISTDRLQ YFHLVWFLTT YHRLKVQALK SHYKHQLKAV QKKTTELQNA LDFTTPPPPA PEKPGYDEKA VLSTLDMFSF NFVLQSIENY ATMNNYHGMT VSVQLLAEMM AYLAELTASD DSRFQRIADS LQHKIFYERD FLDRLPVLLK TWSPGLFPNA YVVDVVTLTH LVFKVLDSQG TIKVLSRRKA YLDKKRQKKK RKDGESKDGE NSDDSSTDEE ETERRAQLLM EMQRKEADFD VRKYFSSMVS ADTIRMYCSL LAYYRENSAK VNHYIHSFFY RTKHFQIYQQ EAWTMQPMLF NIHMLLLFNK MLQDSYIQRL PEYKNFLDFI RGVVRDFFTL ADKNNLLFVE ALLRQTYPSK SCMLIQRSYD PIDSMSKSKS EAVALGRERR IEALNESRRH RIALDHEELE GEAEFQFTLG PADFQSTSLV DKESKEDEGE AGGNVAGSSE AASAAKPKTK RKTPLSRAAT ERAKNWSKVE DRYLAKAYMK FRHLPSVYEV ISYEDMFQER DRTPEQIERR VKYLKLHRKT HDSSDEEENE LSASDGEHNG ELEENTVRES RLEKDLARLE TARPRRRLRR GADLSDDDSD DDMVLGGPC // ID D2H357_AILME Unreviewed; 1204 AA. AC D2H357; DT 09-FEB-2010, integrated into UniProtKB/TrEMBL. DT 09-FEB-2010, sequence version 1. DT 14-MAY-2014, entry version 16. DE SubName: Full=Putative uncharacterized protein; DE Flags: Fragment; GN ORFNames=PANDA_004092; OS Ailuropoda melanoleuca (Giant panda). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; OC Ailuropoda. OX NCBI_TaxID=9646; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=20010809; DOI=10.1038/nature08696; RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., RA Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., RA Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., RA Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., RA Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., RA Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., RA Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., RA Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., RA Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., RA Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., RA Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., RA Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., RA Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., RA Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., RA Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., RA Wang J., Wang J.; RT "The sequence and de novo assembly of the giant panda genome."; RL Nature 463:311-317(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL192457; EFB28855.1; -; Genomic_DNA. DR HOGENOM; HOG000133002; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; FT NON_TER 1204 1204 SQ SEQUENCE 1204 AA; 138394 MW; 9FFB162007B37011 CRC64; MDLNMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDDTRD VRQQLGAAQI LQSDLLPILI QHRRDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLAYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP TDLDQEKRID DDASVHDQLL WAVHLSGLDD LLLFLASSPA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSTDV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLQNYSSD LGKQPRRVPK RRQAARELSV QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPALVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMSPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRKKKKKVLD WPVAPGNVPS SAGELEAVWP SLAEQLQCCA QDPELSLDSV VPFDAASEVP VEEQRAEAMV QIQDCLLAGQ APQALTLLRS AREVWPEGDV FGSQDISAEE ELQLLKQILC APLPRQQGPE DRGPEEEEEE EEEEEVQAVR VSEKEFNFLD YLKRFASSTV VRAYVLLLRG YRQNGAHTNH CIVKMLHRLA HDLKMDALLF QLSLFCLFNR LLSDPAAGAY TELVTFAKYI LGKFFALAAV NQKAFVELLF WKNTAVVREM AEGYGSLDGG SSSRKPPIWT PEEEAQLQEL YLAHKDVEGQ DVVDVILAHL KTPRTRKQVI HQLVRLGLAD SVKEFQRKGT HIVLWTEDQE LELQRLFEEF QDSDDVLGHI MKNITARRSR ARIVDKLLAL GLVAERRELY KKRRKKLAPS SSPKGEESRK DFCQEDLEEE ENLPEEESDE DEEKEEDSEA DKAERSPVLS AETLGQSLSQ EGFSAPLLWL QSCLMRVADD REEDGCSQPV PLVPLTEENE EAMENEQFQQ LLRKLGVRPP ASGQETFWRI PAKLSPTQLR RVAASLSQPE EELQPGPEPK VPGEQGPEEE HKKEHRSQAR RALVLARKEK AGLVSPEEEG AAGEKEQLKM APRKRQLLDS DEEQEEDEGR SKAPESRAPE IQKKKRFQIE DEDE // ID D2T1E9_ACYPI Unreviewed; 447 AA. AC D2T1E9; DT 02-MAR-2010, integrated into UniProtKB/TrEMBL. DT 02-MAR-2010, sequence version 1. DT 03-OCT-2012, entry version 4. DE SubName: Full=Timeless; DE Flags: Fragment; GN Name=tim; OS Acyrthosiphon pisum (Pea aphid). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Paraneoptera; Hemiptera; Sternorrhyncha; OC Aphidiformes; Aphidoidea; Aphididae; Macrosiphini; Acyrthosiphon. OX NCBI_TaxID=7029; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=YR2; RA Cortes T., Ortiz-Rivas B., Miralles S., Gonzalez A., RA Martinez-Torres D.; RT "Characterization of the circadian rhythm clockwork in the pea aphid RT Acyrthosiphon pisum (Hemiptera: Aphididae)."; RL Submitted (FEB-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FM998651; CAX37109.1; -; mRNA. DR UniGene; Aps.26332; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 FT NON_TER 447 447 SQ SEQUENCE 447 AA; 52681 MW; B8D463F3327238A8 CRC64; YENTILWMFF SEQFDEIIIS LIANSNRGHW AVLIIELIAL IFKNQHVEQM SKQFIKMNET KKFDSSEDNE SNSSSKYPKH GRHSSPEHLS ELSNKDSDND TNFKLNKIIG DLRKNSLMDE EDRSSKEAII HSLNVHTIKD KLDSPKTKFE ELLQGDDVKT SNSNNFNKVS RRNSYTETRR NSNRESRRNS LEQIKFEFEM KSYKPTLGSA ILRRKKYIKK NSKTKLKLPL FPKQFNEPRE TYMISYFLQK FTVCFLQNGF NTLVDELYNL LTSNSHIDTS LYFWILTYFC RFCKFNNIKL ELVRQIVSFK LISFIVHEGL KISEELRIAK LQKSPNIHLK VRHLHLAIMA IKEVIKTIEF YRQTAVESPI YAHLINDLQN SGNTSPESIT WAKDIKSLFT LLIRYYDSDI QIIEYLHDLI VTNHMVLSLF DAFKDYWNLN DNITAYI // ID D3BEF2_POLPA Unreviewed; 1392 AA. AC D3BEF2; DT 23-MAR-2010, integrated into UniProtKB/TrEMBL. DT 23-MAR-2010, sequence version 1. DT 21-SEP-2011, entry version 4. DE SubName: Full=Timeless family protein; GN ORFNames=PPL_07111; OS Polysphondylium pallidum (Cellular slime mold). OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Polysphondylium. OX NCBI_TaxID=13642; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PN500; RA Gloeckner G., Schaap P., Noegel A.A., Felder M., Eichinger L., RA Heidel A.J., Platzer M.; RT "Living fossils from the dawn of multicellularity."; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ADBJ01000031; EFA80283.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1392 AA; 160575 MW; 1C54D24ABA4300EB CRC64; MDEQNLINIV EELGQFETNS DKKKVFVKGE ECLAALSELF RQLKRDDEQY RDVFITIGSW SIISKKLIPL ALHYPDDTIL IINILKIMVK FTLPINRDSQ NIAKQKEILC DFKESFINKE FIALLLSLLR DPIGRLYSES RSNSPQSKTD CALIELVLSL IRNIVKIPDP DASNAKEHQF FMQEEFIILL YKEKFLELFL TLSQTMKENK LFSSNPLFSL LLLEIFSEIL GRENPQNVWL APIDLEITQD TTSQQQLLQQ QQKKQQQQSV DPLAQLRMKE NNLKKLNNAN RGSSSASRFR GTFTQIASAV SGGSRIYNNA LPSADGATEI RQLTSQPLTL SNLSKSVDAN TTLLHGKKKG MTSRPQSHSS QYLLGILREW ATQFLDGCYN VLMEIVVYEL SRSESSILES DRFNFLSFTY FFTSFALTML QSRNRDIANN NNNNNNNTTE SDGQSSLDNI ILGCVASTLS LNTFNFIFEC IELYMGHTNI RKVDYVPLEN TVSTLCSMVS ILSYMASSDQ QEIVNMSRKM QQKIYFNREV FLSGVVKLMR RYDARVHSNA MLLDITNLAY TTIHMLDQFC KLQDSNAISI KKKSKMSATR VHVDKEDGDD DDNEGEAGDK DNNEDNEDNS DKDYEDELER DNEKQQELAT KSMSIESFIS DFAHPDIINN LCNLLGKWIS NSQTTNFQLV SLVKRFISIG LEGCFYRLSI FYMFNSFLND PIISRDKNAT ELLEIISQIL ERYFKKAENS NLLYLKLLTP KSVNSIIAMD LDDKLADIES DPLGDSGEYQ QDKIPTKSRL TKKQRQAEED KNETYLDSDE DDAMIKRSSK IDEEEEEKKK EEEEEGVDNY SSDDEISLGD KVVTLEEKAD QKRITKYIKI ITKKSNGDAI LMWVKDNLIS AMSLREREAS QLKGKFTMHT FKTSIVEKDY CSSKTVKKLF KLFKLEVSKK GEFTIPESKL YNHSYLSFLH KQIEKVELSV LDKEQNRSKH KVDEEKEEEE QEEDKEEEKE EEKEEEKEVE KEDQEEEEQE EEEQEEKELS KKSNINSKNN EKKSTKKSNT SEDESDAMDV DNVVVNIKET ASNDVEEENK EEDNEESEEE PKRVTRSVIS NKNKKKSKQL EVKSNKSKQT KETKSRNNKK QAKEIKKKKK DSSSEEEEEE EEEEEKEVKE KKSSKQNNTK KTPPPPTKNN NREKESSEEE EEEEEEKEIS KNSKDSSDEE IVRVKRVVNS KKMKQMEKKK QTVEKKKKKK QDSSDDDDSD SNSKNKNKRQ KAVVDSSEEE SSDGEPAVAS KKQSKSTKET KVNSKNNVNN SKEKDNDSDS ESEEDKDKDN SVLVKRKFDN TAIKKFDIKR IKQAVEVSKT KRKQQQEEEE DDDDEENSDK KQQSQKPESI SY // ID D4B5G1_ARTBC Unreviewed; 1141 AA. AC D4B5G1; DT 18-MAY-2010, integrated into UniProtKB/TrEMBL. DT 18-MAY-2010, sequence version 1. DT 13-NOV-2013, entry version 11. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=ARB_03701; OS Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) OS (Trichophyton mentagrophytes). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Arthroderma. OX NCBI_TaxID=663331; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4681 / CBS 112371; RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7; RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S., RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., RA Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., RA Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C., RA Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F., RA Monod M., Brakhage A.A.; RT "Comparative and functional genomics provide insights into the RT pathogenicity of dermatophytic fungi."; RL Genome Biol. 12:R7.1-R7.16(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABSU01000041; EFE29405.1; -; Genomic_DNA. DR RefSeq; XP_003010045.1; XM_003009999.1. DR GeneID; 9525666; -. DR KEGG; abe:ARB_03701; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1141 AA; 129200 MW; 22797156AFADFAE8 CRC64; MDGEPFVAQP GDQVVDPEVR SFIYGLVTAL GGSANDEAGR YILGDDALGC LRDLKKWLRF YDEKLNRLDV SRCIAESNLV NGDLVPILAL WDEVKPTDNE MTVNHHRHTP YLQHAQVSYK TGILAHPSNS ILRSIIRIGL PSITTPREER SSRDEGILKL VLYLFRNVVI LGATPNLAVE GDEDEASRSM TINAFHDQDV FALILTLCSN IGEEFTFQDV ILLEILFHLV KGVDVRQLFM DDNQRSATRI DELKGLMAAE SNLNRDRSKN APTRHGRFGT MIWVKRDAAK VSSVSGQDVL LNDQAAFDKM DKTKKWNKPR GRRPVIDETS NNFNVQVHLT SSALNYLRLF VEEFLDSGFN PLMTSIRKAM ERESDRLSES SSRHFFFVSS WFLSAERARR EQQEKARRKA TGSARDIEPD SFALVASVLN QETFIALNRY MQASLDNKEW QDLSAGMLSF TQTLLTVQEM SKSALEEDQE IAENILSRIF YEESTHDRIL STLRGYKGQG FWYLDACTEL AHVFLRMLEQ YSKQNVDMQV RSKRISRRKK KAQNKAQGNQ EDQEGEFGNS EDEEEKDRAE AVRNVAERSF DFKRFCNKFC TQNSVNTFVA LTSYYRDLNT EQLKRAHRFF YRVAFKQELS VLLFRLDIIA LFTRMIKGPE GLLSSSPAFG EWEELLFKKI DERPELITEL LFSKIPATVH YLEYGQEKQT VSGASRPAAE LEVKQNYTRT ADEKIRIVVS VLVADNCEPL VRWLCEVLDN ALKDRKSWDL ADLARGIQDA ADIADIAPST PAIEVSAPDE KCKTALFRNG RLRLLFTLAG LELVGEDVLG TPWSIPGSIP STELEETRNS IQKHCDDPAT EIDGVDPHKL ILRKRIAAKS TNDEATTQVN FGNDSEGEDL GLDEILFPPN PRSKSKALKE LKQKRRKKTD ADEDHQLDEE TLNARRLARE QNALERQRKI KSSLFVNASD DETDDEADQE FFAREAERRK RQAQLVEEAM NIDGLGSTVL GDSTKKARGK RKQAISSESD GEDISTSQRK RARSEDLGSG NEEEEELGAP PRRKVQTPPT STEDDLILDV GEKASAPSFQ WTSTAVDRPS KPTATSEQNI DDDDEDDEPV TTTRPRRPKI MAGFVVDSDS E // ID D4CZN3_TRIVH Unreviewed; 1049 AA. AC D4CZN3; DT 18-MAY-2010, integrated into UniProtKB/TrEMBL. DT 18-MAY-2010, sequence version 1. DT 13-NOV-2013, entry version 9. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=TRV_00275; OS Trichophyton verrucosum (strain HKI 0517). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; OC mitosporic Arthrodermataceae; Trichophyton. OX NCBI_TaxID=663202; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=HKI 0517; RX PubMed=21247460; DOI=10.1186/gb-2011-12-1-r7; RA Burmester A., Shelest E., Gloeckner G., Heddergott C., Schindler S., RA Staib P., Heidel A., Felder M., Petzold A., Szafranski K., RA Feuermann M., Pedruzzi I., Priebe S., Groth M., Winkler R., Li W., RA Kniemeyer O., Schroeckh V., Hertweck C., Hube B., White T.C., RA Platzer M., Guthke R., Heitman J., Woestemeyer J., Zipfel P.F., RA Monod M., Brakhage A.A.; RT "Comparative and functional genomics provide insights into the RT pathogenicity of dermatophytic fungi."; RL Genome Biol. 12:R7.1-R7.16(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACYE01000016; EFE44902.1; -; Genomic_DNA. DR RefSeq; XP_003025513.1; XM_003025467.1. DR GeneID; 9581750; -. DR KEGG; tve:TRV_00275; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1049 AA; 119242 MW; 82EBAE7B12F07230 CRC64; MTVNHHRHTP YLQHAQVSYK TGILAHPSNS ILRSIIRIGL PSITTPREER SSRDEGILKL VLYLFRNVVI LGATPNLAVE GDEDEASRSM TINAFHDQDV FALILTLCSN IGEEFTFQDV ILLEILFHLV KGVDVRQIFM DDNQRSATRK DELKGLMAAE SNLNRDRLKN APTRHGRFGT MIWVKRDAAK VSSVSGQDVL LNDQAAFDKM DKTKKWNKPR GRRPVIDETS NNFNVQVHLT SSALNYLRLF VEEFLDSGFN PLMTSIRKAM ERESDRLSES SSRHFFFVSS WFLSAERARR EQQEKARRNA TGSARDIDPD SFALVASVLN QETFIALNRY MQASLDNKEW QDLSAGMLSF TQTLLTVQEM SKSSLEEDQE IAENILSRIF YEESTHDRIL STLRGYKGQG FWYLDACTEL AHVFLRMLEQ YSKQNVDMQV RSKRISRRKK KAQNKAQGNQ EDQEGEFDNS EDEEEKDRAE AVRNVAERSF DFKRFCNKFC TQNSVNTFVA LTSYYRDLNT EQLKRAHRFF YRVAFKQELS VLLFRLDIIA LFTRMIKGPE GLLSSSPAFG EWEELVRQIL KKMFKKIDER PELITELLFS KIPATVHYLE YGQEKQTVSV ASRPAAELEV KQNYTRTADE KIRIVVSVLV ADNCEELVRW LCEVLDNALK DRKSWDLADL ARGIQDAADI ADIAPSTPTI EVSAPDEKRK TALFKNGRLR LLFTLAGLEL VGEDVLGTPW SIPGSIPSTE LEETRNSIQK HCDDPATEID GVDPHKLILR KRIAAKSMND EATTQVNFGN DSEGEDLGLD EILFPPNPRS KSKALKELKQ KRRKKTDADE DNQLDEETLN ARRLAREQNA LERQRKIKSS LFVNASDDET DDEADQEFFA REAERRKRQA QLVEEAMNID GLGSTVLGDG TKKATSGKRK QAISSESDGE DIGTSQRKRA RSEDLGSGNE EEDELGAPPR RKVQTPPTST EDDLILDVGE KASAPDFQWA STAVDRPSKP TATNKQNIDD DDEDDEPVTT TRPRRPKMMA GFVVDSDSE // ID D5G6E4_TUBMM Unreviewed; 1117 AA. AC D5G6E4; DT 15-JUN-2010, integrated into UniProtKB/TrEMBL. DT 15-JUN-2010, sequence version 1. DT 13-NOV-2013, entry version 11. DE SubName: Full=Whole genome shotgun sequence assembly, scaffold_12, strain Mel28; GN ORFNames=GSTUM_00004446001; OS Tuber melanosporum (strain Mel28) (Perigord black truffle). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Pezizomycetes; OC Pezizales; Tuberaceae; Tuber. OX NCBI_TaxID=656061; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Mel28; RX PubMed=20348908; DOI=10.1038/nature08867; RA Martin F., Kohler A., Murat C., Balestrini R., Coutinho P.M., RA Jaillon O., Montanini B., Morin E., Noel B., Percudani R., Porcel B., RA Rubini A., Amicucci A., Amselem J., Anthouard V., Arcioni S., RA Artiguenave F., Aury J.M., Ballario P., Bolchi A., Brenna A., Brun A., RA Buee M., Cantarel B., Chevalier G., Couloux A., Da Silva C., RA Denoeud F., Duplessis S., Ghignone S., Hilselberger B., Iotti M., RA Marcais B., Mello A., Miranda M., Pacioni G., Quesneville H., RA Riccioni C., Ruotolo R., Splivallo R., Stocchi V., Tisserant E., RA Viscomi A.R., Zambonelli A., Zampieri E., Henrissat B., Lebrun M.H., RA Paolocci F., Bonfante P., Ottonello S., Wincker P.; RT "Perigord black truffle genome uncovers evolutionary origins and RT mechanisms of symbiosis."; RL Nature 464:1033-1038(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN430009; CAZ80087.1; -; Genomic_DNA. DR RefSeq; XP_002835930.1; XM_002835884.1. DR EnsemblFungi; CAZ80087; CAZ80087; GSTUM_00004446001. DR GeneID; 9181172; -. DR KEGG; tml:GSTUM_00004446001; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1117 AA; 126803 MW; C510387D6B401CC9 CRC64; MSSEGEGDMV LSRLPETVDP MILGGTSMVE DGGYSLGDDA LACLKDLKRW LKLYDQKMNR FDVARCMAEA NLVKGDLLEI LSGWEKDEIE NRIKQRLALG CVELLVPLTW PFERYNSQTT VNHHRHIPVL QFAQAGYKKA ILQHPSKRIL SNIVRVALPS IAVPPNERTE RDEGIIKLVL YFFRNLVMIE HPMITETDTG EEISRSATIE ALKEQNVLHL LLAMSSEMGN EFNTQDVVVM EVIYHLVKSV DIEKMFLTDE QESQKQGQDL TALLKLEDEM KRASIRGAST RHNRFGTTVW IERGDKTRSF VSGQGALLGK STGLDKMDAS KKWKKPGGAD TKGISRKTEH DMSLTLERRA KAKLREFVEG FLDAGFNPLF SHLRRAIDRD AQRLVESNQQ QYFYLIAWFL KAERTRRKTF ANSEDPETSD IESFSLVASV LNQESLITLN RRMTDWFDTK QWTPLQSAMR CFTQILLTVQ DMAVSPLEDD QDIAENIQNR LFYEEVTLDL VVMILRAYTR QPFGWLDDCT EMVHVHLRML ERFSKQHEHM FIRSRKRARA QRKKNPTSED GDGGVPEEGD EEMAELSKAT MKERAFDYSR FEQKFLTQSC VNTFLAFIGN YKELNYSQMK RAIVFFHRVF VKREQEVLLF RIDIVELFNR ILQGPDGLPS SHSARKEVDQ FFKHYMRKLV KMLEKRPELY VELLFTKINS TMHYLQFGYE KQINVSKPRE AAELRIKPGL EFNEQVSVAV GALLDENKGD AVDWLKTVLA AAISERKSWE AGEEARLALG AEAADPDSET NPQAPPSPPP FINITPDNEV RQTALLKDGK LRLLLTTLKF EKIDAVDTLN TRWIIPSQLT SIDLQTSLEL LKLNTDNPPI FPDGHLAEDF ISRKPKPRVP AFDSDSGSDL EPLFEPGGPT PMPGAEKPKK KSARKRRRKD PMESTELGSD LDDAAIERAL ARRQKEKERM VMIKSSLFVH DSDDESDEER DKLFYEKERM QAAMGPVGLD GSAGPQMDFM EYGFGGVGED WAGSTGAGEG NGRKRKNVAG GQAKAKKRRA IESGSDDDNG SSADEESSDD GDGEERPFAK PPTMPDVRTP PARPRRRGPV IVSSDEE // ID D6W9F2_TRICA Unreviewed; 1255 AA. AC D6W9F2; DT 10-AUG-2010, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Timeout; GN Name=tim2; ORFNames=TcasGA2_TC000593; OS Tribolium castaneum (Red flour beetle). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; OC Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium. OX NCBI_TaxID=7070; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Georgia GA2; RX PubMed=18362917; DOI=10.1038/nature06784; RG Tribolium Genome Sequencing Consortium; RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R., RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., RA Friedrich M., Grimmelikhuijzen C.J., Klingler M., Lorenzen M., RA Richards S., Roth S., Schroder R., Tautz D., Zdobnov E.M., Muzny D., RA Gibbs R.A., Weinstock G.M., Attaway T., Bell S., Buhay C.J., RA Chandrabose M.N., Chavez D., Clerk-Blankenburg K.P., Cree A., Dao M., RA Davis C., Chacko J., Dinh H., Dugan-Rocha S., Fowler G., Garner T.T., RA Garnes J., Gnirke A., Hawes A., Hernandez J., Hines S., Holder M., RA Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Jackson L., Kovar C., RA Kowis A., Lee S., Lewis L.R., Margolis J., Morgan M., Nazareth L.V., RA Nguyen N., Okwuonu G., Parker D., Richards S., Ruiz S.J., RA Santibanez J., Savard J., Scherer S.E., Schneider B., Sodergren E., RA Tautz D., Vattahil S., Villasana D., White C.S., Wright R., Park Y., RA Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L., RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y., RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G., RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., RA Brown S.J., Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., RA Lorenzen M., Maselli V., Osanai M., Park Y., Robertson H.M., Tu Z., RA Wang J.J., Wang S., Richards S., Song H., Zhang L., Sodergren E., RA Werner D., Stanke M., Morgenstern B., Solovyev V., Kosarev P., RA Brown G., Chen H.C., Ermolaeva O., Hlavina W., Kapustin Y., RA Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V., RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M., RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., RA Aranda M., Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., RA Bopp D., Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., RA Ferrier D.E., Friedrich M., Gordon C.M., Jindra M., Klingler M., RA Lan Q., Lattorff H.M., Laudet V., von Levetsow C., Liu Z., Lutz R., RA Lynch J.A., da Fonseca R.N., Posnien N., Reuter R., Roth S., RA Savard J., Schinko J.B., Schmitt C., Schoppmeier M., Schroder R., RA Shippy T.D., Simonnet F., Marques-Souza H., Tautz D., Tomoyasu Y., RA Trauner J., Van der Zee M., Vervoort M., Wittkopp N., Wimmer E.A., RA Yang X., Jones A.K., Sattelle D.B., Ebert P.R., Nelson D., Scott J.G., RA Beeman R.W., Muthukrishnan S., Kramer K.J., Arakane Y., Beeman R.W., RA Zhu Q., Hogenkamp D., Dixit R., Oppert B., Jiang H., Zou Z., RA Marshall J., Elpidina E., Vinokurov K., Oppert C., Zou Z., Evans J., RA Lu Z., Zhao P., Sumathipala N., Altincicek B., Vilcinskas A., RA Williams M., Hultmark D., Hetru C., Jiang H., Grimmelikhuijzen C.J., RA Hauser F., Cazzamali G., Williamson M., Park Y., Li B., Tanaka Y., RA Predel R., Neupert S., Schachtner J., Verleyen P., Raible F., Bork P., RA Friedrich M., Walden K.K., Robertson H.M., Angeli S., Foret S., RA Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W., RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.; RT "The genome of the model beetle and pest Tribolium castaneum."; RL Nature 452:949-955(2008). RN [2] RP GENOME REANNOTATION. RC STRAIN=Georgia GA2; RX PubMed=19820115; DOI=10.1093/nar/gkp807; RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W., RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.; RT "BeetleBase in 2010: revisions to provide comprehensive genomic RT information for Tribolium castaneum."; RL Nucleic Acids Res. 38:D437-D442(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000277; EEZ99220.1; -; Genomic_DNA. DR EnsemblMetazoa; TCOGS2:TC000593-RA; TCOGS2:TC000593-PA; TCOGS2:TC000593. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; D6W9F2; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1255 AA; 144950 MW; 7CE5B670528F7F9C CRC64; MSSLLSAELA ATCSALGYYD ATSNKYYADS NTLETVKDLI RYLRRDDESH DIRRQLGEIK VLQNDLVPLL KSYWEETDLF DVLLRLLVNL TTPALMLWNE ELPTDKITRN HYLQIEDHLK SYKQTFADET FWAVLSTRLS KILETSYAER GDENSLIIER ILILIRNILY VPPDPNTEKR PDNDASIHDQ VLWALHQSGM LDIILFITSS TNEKAYYMHT LEILSFMLRE QKAAELARAA LQRSETEKMR DEAELLAIRH RETNQKQQKI KLYNGARHSR FGGTYVLKSM KSISDNELIY HKPLNKLEAL NFDADKRKPK TPKNRMPVQS STFERRSAFS IRLFLKEFCV EFLNGAYNTL MYHVKDNLVR ARAQAHDESY YLWALRFFME FNRCYKFEVK LVSETMAVQT FRYVQQLTEK YFDMIQSDKK NAVLWSRRLH LALLAYRELF LTLCAMDKSP DETVRDSARV IKSNIFYIVE YREFVITLLM TYDELKMSNA YLKDLMETQH VFIKLLESFC GSNGSVVVQK KLKKKGRKKK ASQDDGVPQP DVNLERRWDE AAPQLSTVLE GNADFSTDVV PFDAASDVPI DEQKAEAMKN VQRKLRNADY ENAISLLRAA REVWPENNCF GSNNMAPEEE FLALRDIFFA DLGDDEPTPT IEEQPIYDEN DEEEDEEAGY GEVNFKFTDF SKRLAHPRIV RACGLALRDF ESNSVNTNHC IIKLLHRIAF DCKLYVMIFQ VSIFRTFQKI YANKDFPQYR ELVKFATYII RQFIKITEIN KKVYMESLFF KNTNEAYEIE HGYGTTKKAP SRGWTEEEED ELRRLFMEHQ TNQLQDDVVD WIVNNLIDNT RTRRAVLKKL KDMCLLVNPA TMRKSTRCEW GDEEVMQLRA LFHEFRDAAD PLGCIMPRLE VKRSRQMLTK KLLDLGVIRD KADVRKKRGG AKRPTATRRD SDSESNGSED DDYGGGASRG DNSAAQRNTT KTKSKKKKPV TRQVNMASDA RIAALFIKLV ESGMSEALEW LKDSFSDAVE DFENDDGCEG IPLVPIMDYA VNAMENADFI ETLKALGVAE PFDEQEMYWR IPGNLSVDVI RKYIDLLQQA VDNTLTVPES QQTGETKNIA PPTSLKKKKK IRNLVDSEDD ASNDGARETE DGDEDKSQNR KQKQGRNVVS SDEDETNDGA NNTQTSVSRS RCVIESDEEE DNSTVSPQVK KSVRRIIDED EDEENDINKR NRIESDSEAE KPAPKRTRTI SSDED // ID D6WJ29_TRICA Unreviewed; 1107 AA. AC D6WJ29; DT 10-AUG-2010, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 1. DT 13-NOV-2013, entry version 15. DE SubName: Full=Timeless; GN Name=tim; ORFNames=TcasGA2_TC013997; OS Tribolium castaneum (Red flour beetle). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Coleoptera; Polyphaga; OC Cucujiformia; Tenebrionidae; Tenebrionidae incertae sedis; Tribolium. OX NCBI_TaxID=7070; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Georgia GA2; RX PubMed=18362917; DOI=10.1038/nature06784; RG Tribolium Genome Sequencing Consortium; RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R., RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., RA Friedrich M., Grimmelikhuijzen C.J., Klingler M., Lorenzen M., RA Richards S., Roth S., Schroder R., Tautz D., Zdobnov E.M., Muzny D., RA Gibbs R.A., Weinstock G.M., Attaway T., Bell S., Buhay C.J., RA Chandrabose M.N., Chavez D., Clerk-Blankenburg K.P., Cree A., Dao M., RA Davis C., Chacko J., Dinh H., Dugan-Rocha S., Fowler G., Garner T.T., RA Garnes J., Gnirke A., Hawes A., Hernandez J., Hines S., Holder M., RA Hume J., Jhangiani S.N., Joshi V., Khan Z.M., Jackson L., Kovar C., RA Kowis A., Lee S., Lewis L.R., Margolis J., Morgan M., Nazareth L.V., RA Nguyen N., Okwuonu G., Parker D., Richards S., Ruiz S.J., RA Santibanez J., Savard J., Scherer S.E., Schneider B., Sodergren E., RA Tautz D., Vattahil S., Villasana D., White C.S., Wright R., Park Y., RA Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L., RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y., RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G., RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., RA Brown S.J., Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., RA Lorenzen M., Maselli V., Osanai M., Park Y., Robertson H.M., Tu Z., RA Wang J.J., Wang S., Richards S., Song H., Zhang L., Sodergren E., RA Werner D., Stanke M., Morgenstern B., Solovyev V., Kosarev P., RA Brown G., Chen H.C., Ermolaeva O., Hlavina W., Kapustin Y., RA Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V., RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M., RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., RA Aranda M., Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., RA Bopp D., Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., RA Ferrier D.E., Friedrich M., Gordon C.M., Jindra M., Klingler M., RA Lan Q., Lattorff H.M., Laudet V., von Levetsow C., Liu Z., Lutz R., RA Lynch J.A., da Fonseca R.N., Posnien N., Reuter R., Roth S., RA Savard J., Schinko J.B., Schmitt C., Schoppmeier M., Schroder R., RA Shippy T.D., Simonnet F., Marques-Souza H., Tautz D., Tomoyasu Y., RA Trauner J., Van der Zee M., Vervoort M., Wittkopp N., Wimmer E.A., RA Yang X., Jones A.K., Sattelle D.B., Ebert P.R., Nelson D., Scott J.G., RA Beeman R.W., Muthukrishnan S., Kramer K.J., Arakane Y., Beeman R.W., RA Zhu Q., Hogenkamp D., Dixit R., Oppert B., Jiang H., Zou Z., RA Marshall J., Elpidina E., Vinokurov K., Oppert C., Zou Z., Evans J., RA Lu Z., Zhao P., Sumathipala N., Altincicek B., Vilcinskas A., RA Williams M., Hultmark D., Hetru C., Jiang H., Grimmelikhuijzen C.J., RA Hauser F., Cazzamali G., Williamson M., Park Y., Li B., Tanaka Y., RA Predel R., Neupert S., Schachtner J., Verleyen P., Raible F., Bork P., RA Friedrich M., Walden K.K., Robertson H.M., Angeli S., Foret S., RA Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W., RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.; RT "The genome of the model beetle and pest Tribolium castaneum."; RL Nature 452:949-955(2008). RN [2] RP GENOME REANNOTATION. RC STRAIN=Georgia GA2; RX PubMed=19820115; DOI=10.1093/nar/gkp807; RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W., RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.; RT "BeetleBase in 2010: revisions to provide comprehensive genomic RT information for Tribolium castaneum."; RL Nucleic Acids Res. 38:D437-D442(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000280; EFA04644.1; -; Genomic_DNA. DR EnsemblMetazoa; TCOGS2:TC013997-RA; TCOGS2:TC013997-PA; TCOGS2:TC013997. DR OMA; LHIPETH; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; D6WJ29; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1107 AA; 127212 MW; 3A84CF8542C0E2B9 CRC64; MAHIHNMFAS ICVRNGDTLI INDDCYEILQ EILRELLTED STLRTYRRAI GFGQNIKKDL IPLLTYLKDD AKESTRIIDT IIKILVNLTI PIEYLLPLEA MSQTDVGRHT IFELTKLLTS SKEAFTDSRS TKLIMDHVKF IVESDLEMNL EYCDSINNCL LLLRNILHVP EVKSVQNNAL THSSMQNQII WNLFTQSIDK VIIYLISCPQ KMYWGVTMVQ LIALLYKDQH VGTLQKLLNL WLEASLSESS EDNESNTSPP EQGSDDSSPI ITSDPTSDSS DGGGGKRNKT LNSTNLERNK KTLMMRGKST ETETSTSSGV STAHTSIDSA DSPKNDKAPL KNKRECPSSQ SEDFGYVTQV ENQESISTSS NEEDQPQLKP VHQKPHTFQK SRYNTGKSRA ATALDKKELR RKKLVKRSKT NTINMKGLLH HLPTDEDIAN ILKEFTVDFL LKGYGILVQD LHSQFLTNIH LQIDTSHFFW LVTYFLKFAT QLELDLEHVS PVLSHEILSY LVFQGVWIYE ELEMSGKIPD FDLKPCLRRL HLVVTAIREF LQAVETYQKM IHLSEDDRLA LLKLQNQITE MEDLRSLFLL LLRQYNPNIQ SRQYLQDLIL TNHNYLLFLD SATKERRSFN MMEHLKQFAT VEIMRQYGLL LESFKENGEF VNNCIFTMMH HIGGDLEHVA TLFQPSILKT FSLIWETDYE ICDDWSDLIE YIIHKFINSP RSNSDLNSSE TCHKLVVDEA EWTEEEKDNL LGYYNQSQFS NDTIANITKK YEKCGVRQKT QLSIIRQLLE QNIINESQYN DFIKVKQQPD RLKETKNIIP NQMDFEETPT DEGIRILREY LCKDNKTKFV LWLQKVLINT CYVKLALANP GEFNNDKALG QPVIYYFALL NLPIPVVPWT VDQTAILKYQ SFVLLLHKLG FYLPIDTGKI FVTIPNFWNA EHVFSMAQQL GPIDPAKLNF DVAIFKGRNR RELFKREITD ITNSIQTGKF SMNDSKQTPT MVRYTPLPNS TEWFQNDNFQ SRVLPIADFE VPINSAHPLS ITIPGLEELT CDLPPPELSI VDNHVINANM ECSPIHSACE TASIASDLTR MCVSDEEEKT ILVIEQK // ID D7MSA2_ARALL Unreviewed; 1145 AA. AC D7MSA2; DT 10-AUG-2010, integrated into UniProtKB/TrEMBL. DT 10-AUG-2010, sequence version 1. DT 19-MAR-2014, entry version 18. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=ARALYDRAFT_331651; OS Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=81972; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. MN47; RX PubMed=21478890; DOI=10.1038/ng.807; RA Hu T.T., Pattyn P., Bakker E.G., Cao J., Cheng J.-F., Clark R.M., RA Fahlgren N., Fawcett J.A., Grimwood J., Gundlach H., Haberer G., RA Hollister J.D., Ossowski S., Ottilar R.P., Salamov A.A., RA Schneeberger K., Spannagl M., Wang X., Yang L., Nasrallah M.E., RA Bergelson J., Carrington J.C., Gaut B.S., Schmutz J., Mayer K.F.X., RA Van de Peer Y., Grigoriev I.V., Nordborg M., Weigel D., Guo Y.-L.; RT "The Arabidopsis lyrata genome sequence and the basis of rapid genome RT size change."; RL Nat. Genet. 43:476-481(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL348720; EFH42200.1; -; Genomic_DNA. DR RefSeq; XP_002865941.1; XM_002865895.1. DR EnsemblPlants; fgenesh1_pm.C_scaffold_8000994; fgenesh1_pm.C_scaffold_8000994; fgenesh1_pm.C_scaffold_8000994. DR GeneID; 9302015; -. DR KEGG; aly:ARALYDRAFT_331651; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1145 AA; 129538 MW; 2F31C3377EEB7957 CRC64; MDVEERISTK KKMDLEGLSV ICSDLGVPEE DDDGRRIGYS KSDYCLDNLK DLLRFLRRDD PESREVFKQV CAWNIVAKDL IPIIEHYQDE HNLVLNAVKV LVFLTMPIEP SSDDIPQQLE YLWGLKSAIT FSNIVAVIVS LLEAPLENLE LDVFNEEDWK LVQLVLTLFR NLLAIHDISP IQKAGESTCY FLSLRDQFLE VLSRENVMDI ILVITQTIES FNSLLRHDNL LLLEIYHYIL LGQDMELVAK APDKLDQGKK ASVDSLKTLM KEEEVKRKLA RLNNMNQRHS QFGGTFTQVT MDGTKAVLKG IPSTTESTML KPQQGRGATD KIVWEHGPMS VTNDNSVCED IEKEHPSIQN SDIVTFFQVA QSITSFQFHK SLASNPATGT EETSELSTNQ KAGVNFSKSD ICAPIAATIN DRMFLLVISK WRCAFDGLKE TKDFKFLYAA GSLVKTMLCL LDLVIKLLPE DSREAFTVRI LLYKLFYDQT DQGMCQFILN LVRSFDTHKQ PKSELGDLVE SIHIIVGLME NLQGRGTLRV SKKSRKARKK KPIGNKEATV HKLSENHPST SNEASTEKSI PMVDSTVSTE DGPMDVPPNK PEATNLETET DETQQMHSPK SNNMVDDLSS GSDDSSDGEE QTATDEVDFK VSTFISAFAS NSIIQNICWL LKFYKSNPKQ TNHHVISILR RITEDLELSP MLYQLSLLIT FHKILDEQKV CPCKDYENIV TFLTDLVRNM LKKMKSQPLL FVEILFSKTR KECHYINAEY MLHELGHLRK QMGNQEKVSG TEEYGTSSEK GWARRSLADA LGDDEADVVI SYDQGFQNED DGMVEDISAG PSKRKRRLVL DGDMEIKIKD LYDRYKDDKN CSRLIAENLD PDGGISAAQV TNKLKQLGLE TRKRLRRGDT DHLDATSFAQ PLNTRKRVSS FSKEQETLIK ELYEKFKDQK RCCYLIANEL GSENTYTSTQ VSRKLKQLGL RLPRGKKSEA GMMLKDDHDD SSADKSDDET LLAFKNRKSR KNQKNKQHTR SSNEITPGDS EHYTERNETS QHVPTTGEEE DNDQNYITRE SRESETDVHI SNNAPSTLSP EDPNLSSDHE LEDDELADSG DELADSGDDS AAGVASLTQS PLSRRKLKMV LDEDD // ID D8LBE5_ECTSI Unreviewed; 1045 AA. AC D8LBE5; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2010, sequence version 1. DT 09-JAN-2013, entry version 4. DE SubName: Full=Timeless related protein; GN ORFNames=Esi_0000_0402; OS Ectocarpus siliculosus (Brown alga). OC Eukaryota; Stramenopiles; PX clade; Phaeophyceae; Ectocarpales; OC Ectocarpaceae; Ectocarpus. OX NCBI_TaxID=2880; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Ec32 / CCAP1310/4; RX PubMed=20520714; DOI=10.1038/nature09016; RA Cock J.M., Sterck L., Rouze P., Scornet D., Allen A.E., Amoutzias G., RA Anthouard V., Artiguenave F., Aury J.M., Badger J.H., Beszteri B., RA Billiau K., Bonnet E., Bothwell J.H., Bowler C., Boyen C., RA Brownlee C., Carrano C.J., Charrier B., Cho G.Y., Coelho S.M., RA Collen J., Corre E., Da Silva C., Delage L., Delaroque N., RA Dittami S.M., Doulbeau S., Elias M., Farnham G., Gachon C.M., RA Gschloessl B., Heesch S., Jabbari K., Jubin C., Kawai H., Kimura K., RA Kloareg B., Kupper F.C., Lang D., Le Bail A., Leblanc C., Lerouge P., RA Lohr M., Lopez P.J., Martens C., Maumus F., Michel G., RA Miranda-Saavedra D., Morales J., Moreau H., Motomura T., Nagasato C., RA Napoli C.A., Nelson D.R., Nyvall-Collen P., Peters A.F., Pommier C., RA Potin P., Poulain J., Quesneville H., Read B., Rensing S.A., RA Ritter A., Rousvoal S., Samanta M., Samson G., Schroeder D.C., RA Segurens B., Strittmatter M., Tonon T., Tregear J.W., Valentin K., RA von Dassow P., Yamagishi T., Van de Peer Y., Wincker P.; RT "The Ectocarpus genome and the independent evolution of RT multicellularity in brown algae."; RL Nature 465:617-621(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN647682; CBN76654.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1045 AA; 115904 MW; C87B19CC1E901AA8 CRC64; MSTLEKHMLK ELLLVCSALG SSEASEHGGG DGEPAVQHQR FVRGENCLEW LQDLQRALRR DDENTREICI TLSSWRVVQH KLVPLILECR DDAVLVNTLF KIYVMLTMPL SKQSEEALSK PINPKAQGDV RDQQMRRREN AMSQQAALHA FKRAFISKDV LSVVVGMLEE PLSHTGVART DADNFSIELC LTLLRNVLNI QDPTPGMATS LGDHYTQMHE QLVALFKDAL LLDILLLLAQ DVHARENAKL NLLLVEIFHF IIRDQEPGAI IAVHRLQAQR GASKGSAGLP SPARQSGGSL MSVLAKEKTK RGLGAGQMHS RHARFGGTLQ VGGGNGANAK MVANPFKDRV DCVPQATRKK KKSAKTFTVD DVSGHSSGLS DSHKAILARE ALYEFCCSFL KTAYDPFMRS IKNEFRIDSS RLQPEDKGMM FRLMAFFMSF HHKLHQAAVR DAAEAGQKGV DLPKFELGHV LETMDLMSFN LVLREVETSI TEKSTTRLAG CVAVLKEMMH IVTMLNESSE KAHQLVALGL LARIFYASEP LDKLHDIVRN WQPGKYTKSF LCHVVELVHT TLKTLEWYKK DNHTHIGGVD VSSTDGPDAK GNVDKAVKDR VDSAKKFEFE RYFRRLATNS TVRMYSNLLE HYATNSARTN HYILSFMMRL SNFTGDAPKK RRGETTEQGS GQASDRVTCE PMLYNVYTLG VFQKVLDDPF TRKPSFKHLV HFILSVVRHF GILAQKNHLV FVEAFFQHPQ PHPFCESLVN VYHTASSAHP EDQQSRKKRA ATKSLDTDEE SGSEGEDYQP VTGKAAEGEI GGGDDDLPGV AEDEEEWDEN APDAADEEAE AGGDGEGAVS GRKKGKRDKA GRRRREDKKD AKKVAAGAAK KRAPRWSKKE DAFLREQYPL YAGSTSAVAV LSAADDMEVK QRTEEQIKAR VKKLGLSAAS AASPGEDGGE SADEPLEVPG TENRASSGEE DNAMDDVGAD KPMHVRRLER KNKTESDDDS EGLFSSTEDN DQEQPDRSAQ DATSPQALPR SNKRAILEDS SSDEE // ID D8PUK3_SCHCM Unreviewed; 1209 AA. AC D8PUK3; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2010, sequence version 1. DT 13-NOV-2013, entry version 9. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SCHCODRAFT_255844; OS Schizophyllum commune (strain H4-8 / FGSC 9210) (Split gill fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Agaricales; Schizophyllaceae; OC Schizophyllum. OX NCBI_TaxID=578458; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H4-8 / FGSC 9210; RX PubMed=20622885; DOI=10.1038/nbt.1643; RA Ohm R.A., de Jong J.F., Lugones L.G., Aerts A., Kothe E., RA Stajich J.E., de Vries R.P., Record E., Levasseur A., Baker S.E., RA Bartholomew K.A., Coutinho P.M., Erdmann S., Fowler T.J., RA Gathman A.C., Lombard V., Henrissat B., Knabe N., Kuees U., RA Lilly W.W., Lindquist E., Lucas S., Magnuson J.K., Piumi F., RA Raudaskoski M., Salamov A., Schmutz J., Schwarze F.W.M.R., RA vanKuyk P.A., Horton J.S., Grigoriev I.V., Woesten H.A.B.; RT "Genome sequence of the model mushroom Schizophyllum commune."; RL Nat. Biotechnol. 28:957-963(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL377303; EFI99912.1; -; Genomic_DNA. DR RefSeq; XP_003034815.1; XM_003034769.1. DR GeneID; 9595263; -. DR KEGG; scm:SCHCODRAFT_255844; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1209 AA; 137788 MW; BFA865D5978A9889 CRC64; MSKKRVDIID ISDDDDDAVK TVEKPASDAD DGIEVQEGRP ETEQEFRRRL LEPVISNVVD ALGGFEGKTY RMGDEVNGCL KDLKRLWRKD DTDDERTVAR IYWEKRLLHN DLIPILLATA GKGMVEDKRA VACADLMTAM TWPIDMAEEL KELDDELDRG ADYTVLQQSH LHYKAALLKP DVMKALLSIM IPPLAKPVKE RTERDKQVMT VVLNLIRNLA FIKDLPANIY HSSDQAEFSS LQSKLIRALS ETHAMELLLT IAVNDNNDPL FNQWNTLVLE IFYLLYRGVK PSSLAMDQTK QTSKNLHRLL ETERKIRQDV SRKASSRHSR FGTTITVKLN PKKAAPAADG EEGSSSKKPA GSSHFVLHQQ QALHKNASSI LDMKKKAKKK GMTVDELARE ENLSVEARNI LQKFAAEFVE NCFNPFLSTL IKDIRMERPK ITEKDNLLLL YVAKWFIEFF LLSRAKEKTS TTAKAGDERW NFRLIAEITE RDWIVWVLKR MRQASEDKPK QWTELQAGIE CLTQLLLVID GLCSSADTAY TETAETLQQQ IIYNGEILDI AFESMRNYKQ GTQSLTYLDA SVHLGYSLLK MLERWGKQSG GKDVYVRKKK KVRRRKKRAV NTEEDGIADV EEEEVEVSDN DTIQEAIFTF EAFEMRLAHA EITHTLLTYL SRYKEFTSSE QMKRVTNLLH RQAVRVKAEG LFFKVSTLSL FQRILNDQRS LPREQPYKDL VNLINFILRQ FFKALSENTF LAVEAFFPKN RSQWKQYSSY QEPERKGRAQ ASVVETRWPP DVVVQKGFSW SEELGIAVGA LLEEGHKDLV EWTVEILGLA IATWRGIIAK VDGSKKPEGE DDDDNDAPEP LPLEHQPSAE AMEEMGDFPI PTLDDEKAQA ATKNPHLKLL FRLCKFFVLE EDPSGDELEW YIPKTIMPAE LARFETVIKQ FLEQPYEPED GKKATDFISK KRRPRRKLRS PSPLSEADGD ADYQGEGGGT GEKKERRKRK KRDKGKSKEG EDQDKAERRE RKRAEKRKRE QEQYKSAQFI EDSDLEEGAL EAFLEHEKEL RKRTEARAVN SNLGIGTMRA TGTKKRRRRG EKGERATKKR KGAADEEIVN VDEEQVAVDL SDSDKSDDNQ SDAEDDFEES PAPAPPPRPR PKPRPKPTRK AATPAVTDGE GSDVAGTTTN VAEPNGSESD TVIKRAPRRV QAIVSDEDE // ID D8R0U2_SELML Unreviewed; 1017 AA. AC D8R0U2; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2010, sequence version 1. DT 09-JUL-2014, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SELMODRAFT_406588; OS Selaginella moellendorffii (Spikemoss). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Lycopodiophyta; Isoetopsida; Selaginellales; Selaginellaceae; OC Selaginella. OX NCBI_TaxID=88036; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21551031; DOI=10.1126/science.1203810; RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M., RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., RA Ashton N.W., Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., RA Bonawitz N.D., Chapple C., Cheng C., Correa L.G., Dacre M., RA DeBarry J., Dreyer I., Elias M., Engstrom E.M., Estelle M., Feng L., RA Finet C., Floyd S.K., Frommer W.B., Fujita T., Gramzow L., RA Gutensohn M., Harholt J., Hattori M., Heyl A., Hirai T., Hiwatashi Y., RA Ishikawa M., Iwata M., Karol K.G., Koehler B., Kolukisaoglu U., RA Kubo M., Kurata T., Lalonde S., Li K., Li Y., Litt A., Lyons E., RA Manning G., Maruyama T., Michael T.P., Mikami K., Miyazaki S., RA Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R., Obara M., RA Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B., RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y., RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N., RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N., RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., RA Wakazuki S., Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., RA Zimmer A.D., Zhu Q., Mitros T., Hellsten U., Loque D., Otillar R., RA Salamov A., Schmutz J., Shapiro H., Lindquist E., Lucas S., RA Rokhsar D., Grigoriev I.V.; RT "The Selaginella genome identifies genetic changes associated with the RT evolution of vascular plants."; RL Science 332:960-963(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL377570; EFJ34141.1; -; Genomic_DNA. DR RefSeq; XP_002965303.1; XM_002965257.1. DR EnsemblPlants; EFJ34141; EFJ34141; SELMODRAFT_406588. DR GeneID; 9660508; -. DR KEGG; smo:SELMODRAFT_406588; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1017 AA; 115838 MW; E6CA933FCC775DEE CRC64; MEDEAASSPP RGDDAEKKAT RKNAAAPVLV YAPWSQGARK QDEEIQKKLE TTDERRLASI VSGIGAFETS GSDDWHQGSE VFVKGSHCLE KLRELQRCLT RDNPDSRRVF MQLGQWNVAG KYLVPIIQHY SEDRHLFLAS LKVSILLTLP IDQNSTNTFD QVEYLCQIKE EFRERNVLGA IIAHLEEPLR HLEKGSVSED DWRLLQLVLA FIQNLLAVPE AMNWVGPYPA ERYSQLRDGI LESLFRECGP DIVLAVTKYL PAFKNGIRKD NFLIIQILHH MFWGQKPELL FQASRKDGTR KMVLTSPFQA ADETSKKCPQ VEEPEEKFAR DINVPLPSRD DISVSLKDYA DQFLETGAYN ILVQTFQEDV ERERREIETS DFVTFYEVAE FFLSYQRYKL LKTLADESAL SDSVCGHVSC TMNEETFQMV VSKWHDYTEA AKSPNDWIPV VAVVSLLKEM IHILDLVLKK RSNFSNRDVR TARTLTYKVF YDQTERGILN TCCRSIKAFN NYKQPRRYLE NMVEITHVAL KLMENTIQED GALRVVQKAR NKASRKKQDD SKDLSDAGPE SIEASKASLE ENNDILRGDQ EQAGGDQEQA GGDKEQAQAE PLLDDLQDDH DNVSTREGTF NVLKCVNTFA DSTTVSNYCW LLTFYQSNSP ALNYYIVCML HRICKDCELE PLLYEISILE TFETILLDEK LQKLEEYKFL ISFINKVVRN FFKKLKSNPW LYVDVLFTRS RESSRDIADD YEFEGDTSIT CLADALQEEA DDGFVNLASE STSIIGERGV AHRTVPVPKK RRRGPFNEED EKRIIELFQQ FKHKRSCSKL IAGALDSDGK ISSAQVTRKL KQLGLHRNGT TPSHIHADGT SPIDADRNDD MEDDELDKGN HDGVQPLNEW EDGESSEDNQ GWTESEEDDD EGDLEKGDTE NRTLPAANNA DYVEENRLPS DAEVDLQEVL DVPPGHPVNR KKRLVKHQTA DDASQDMMDL EDLAGTEAEA IPKPAKRRAF TITDDDD // ID D8TGL9_SELML Unreviewed; 245 AA. AC D8TGL9; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2010, sequence version 1. DT 09-JUL-2014, entry version 8. DE SubName: Full=Putative uncharacterized protein; DE Flags: Fragment; GN ORFNames=SELMODRAFT_432638; OS Selaginella moellendorffii (Spikemoss). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Lycopodiophyta; Isoetopsida; Selaginellales; Selaginellaceae; OC Selaginella. OX NCBI_TaxID=88036; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21551031; DOI=10.1126/science.1203810; RA Banks J.A., Nishiyama T., Hasebe M., Bowman J.L., Gribskov M., RA dePamphilis C., Albert V.A., Aono N., Aoyama T., Ambrose B.A., RA Ashton N.W., Axtell M.J., Barker E., Barker M.S., Bennetzen J.L., RA Bonawitz N.D., Chapple C., Cheng C., Correa L.G., Dacre M., RA DeBarry J., Dreyer I., Elias M., Engstrom E.M., Estelle M., Feng L., RA Finet C., Floyd S.K., Frommer W.B., Fujita T., Gramzow L., RA Gutensohn M., Harholt J., Hattori M., Heyl A., Hirai T., Hiwatashi Y., RA Ishikawa M., Iwata M., Karol K.G., Koehler B., Kolukisaoglu U., RA Kubo M., Kurata T., Lalonde S., Li K., Li Y., Litt A., Lyons E., RA Manning G., Maruyama T., Michael T.P., Mikami K., Miyazaki S., RA Morinaga S., Murata T., Mueller-Roeber B., Nelson D.R., Obara M., RA Oguri Y., Olmstead R.G., Onodera N., Petersen B.L., Pils B., RA Prigge M., Rensing S.A., Riano-Pachon D.M., Roberts A.W., Sato Y., RA Scheller H.V., Schulz B., Schulz C., Shakirov E.V., Shibagaki N., RA Shinohara N., Shippen D.E., Soerensen I., Sotooka R., Sugimoto N., RA Sugita M., Sumikawa N., Tanurdzic M., Theissen G., Ulvskov P., RA Wakazuki S., Weng J.K., Willats W.W., Wipf D., Wolf P.G., Yang L., RA Zimmer A.D., Zhu Q., Mitros T., Hellsten U., Loque D., Otillar R., RA Salamov A., Schmutz J., Shapiro H., Lindquist E., Lucas S., RA Rokhsar D., Grigoriev I.V.; RT "The Selaginella genome identifies genetic changes associated with the RT evolution of vascular plants."; RL Science 332:960-963(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL378164; EFJ04196.1; -; Genomic_DNA. DR RefSeq; XP_002994739.1; XM_002994693.1. DR EnsemblPlants; EFJ04196; EFJ04196; SELMODRAFT_432638. DR GeneID; 9652945; -. DR KEGG; smo:SELMODRAFT_432638; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. FT NON_TER 245 245 SQ SEQUENCE 245 AA; 27632 MW; 0648F8CAE31BF01A CRC64; MEDEAASSPP RGDDAEKKAT RKNAAVPVLV YAPWSQGARK QDEEIQKKLE TTDERRLASI VSGIGAFETS GSDDWHQGSE VFVKGSHCLV KVSILLTLPI DQNSTNTFDQ VEYLCQIKEE FRERNVLGAI IAHLEEPLGH LEKGSVSEDD WRLLQLVLAF IQNLLAVPEA MNWVGPYPAE RYSQLRDGIL ESLFRECGPD IVLAVTKHLP AFKNGIRKDN FLIIQILHHM FWGQKPELLF QASRK // ID D8U095_VOLCA Unreviewed; 1475 AA. AC D8U095; DT 05-OCT-2010, integrated into UniProtKB/TrEMBL. DT 05-OCT-2010, sequence version 1. DT 06-MAR-2013, entry version 6. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=VOLCADRAFT_92689; OS Volvox carteri (Green alga). OC Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; OC Chlamydomonadales; Volvocaceae; Volvox. OX NCBI_TaxID=3067; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=f. Nagariensis / Eve; RX PubMed=20616280; DOI=10.1126/science.1188800; RA Prochnik S.E., Umen J., Nedelcu A.M., Hallmann A., Miller S.M., RA Nishii I., Ferris P., Kuo A., Mitros T., Fritz-Laylin L.K., RA Hellsten U., Chapman J., Simakov O., Rensing S.A., Terry A., RA Pangilinan J., Kapitonov V., Jurka J., Salamov A., Shapiro H., RA Schmutz J., Grimwood J., Lindquist E., Lucas S., Grigoriev I.V., RA Schmitt R., Kirk D., Rokhsar D.S.; RT "Genomic analysis of organismal complexity in the multicellular green RT alga Volvox carteri."; RL Science 329:223-226(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL378348; EFJ46824.1; -; Genomic_DNA. DR RefSeq; XP_002952033.1; XM_002951987.1. DR GeneID; 9617253; -. DR KEGG; vcn:VOLCADRAFT_92689; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1475 AA; 156097 MW; F60AA86E5896920C CRC64; MAYGLNLAGA HREQQDAIRG AKDKDSAGDI VMMDLEDDLD DGADDVGADQ DDENEQAAGP QPDPVDYELL ISVAHGLGRW MQDTTTGQKV YVKDQDCIVK VLTYLTMPVD PATSKPEIQE GFVRDVKEAM LQPDALVAVL GLIAEPLAAH PRLSPEQQGA VQLVLVLLRN LLAVPDERPS PTLAAGSSRT RLQASLLSLL FSENILELLL LVAQHGTQAP LRREMPTLLE ILYDTYRNVT PQQLLAAKPP PPPRAAQQQR KQQPAPPKAP AAPTGAAAGG GGGGGVRPSL AAFHSTVAAQ LRRQQLAAAA KLRGAPGGAG VVMSRPGAAG GRFVIAHADD PGQRRTFLAR PAAGGTAATT VKQQIVEAPP KLDGGSRSGA SGSSSGSSWA VRDAVLLWKL RCFADDLLES GYNQVMEVIR RDVSAGVGEA QAAAGGTMGW DTFHLVCKLW VEQADTSAKL RDWELQAVSM RLLCEMLAVL TTALERGGFL VRAKKRRGGV GKRKKQQLEQ EEGEGEKEGD AGEGEGGEGG EGGGEEGEGG KRAGGSGKAP LDELEEGDGG DEDDDDDEDE DEDDDAGGGG GRRGRGGGVE RPLDLTSKIR GKLAQPAVIY FAVQLLACYR SLPPEVPRAI ASLLYRIAGK EHLDMEPLLY QVSVLRVFYM LLSDPDLRSP SKLPYYQGVL LLATRVMLRR RFMKTVRVGN GRSKRSGQAG QAAGNDGGGG RGGLRLNAAQ EALLLSLFER HNASKHNADL ILEGMKRGAG EKEAAGEAAG AGGVEMSLGQ LMRQLKKMGL RFKQLTENQI SRLSSLHSRY RTDPDCHLMI AAQLPGGWTS KDIKRLLVKH GMEQVRRRGT RREEVSGSEA GSDSDSGGGE DGEDDPDVAA LDEEELGVLW EEHGGSPDAA AKIAAALISP VPAAAVTKKL RQMGLMKRDK QKRRKGAGRE GGEEKRRGSR RGGGGEVDVA ALRRLYEEHK ARPDHLNVIA AFLPGGKTVK QVQRLLRAHG LLDDESIRRK RARDAAERTR LVALYQQTRG SAGDQLEAMA RLMPDLAGGP RQVAKLLRKH GLTAAPEGAG RGRGRGKGGS GGGEEEELHQ QGEDEEGERR GKGPRAAGGG SGGAEEHSGG GARSTKVREP DPDRILQALA GIQDAYDADG RWMSPHAAAA WVTKQLTAAE SLWQLAGGAT SDYCLVLTCD EDEDFFMTEY AHDRPSSSPH FLHPQYTHTH THTIPHIPHL PYPNPALNHL NNNPSPPHLK PLSPLPSSPD NDNDDDDDDN DRGGGADGDE GSGGGGRHVV TGHQGAQGRA RGKARAAGAR AQGRAKKRSS KSKSEVGKQE EEQEEEEKEA AAGGTEHPRG RTRRLPDALG GSSGSEGEGD RPTGRNRTAP ATGQPPGRKG GRDVGPAGGA GAGGGGGGGG MAVGASDGGP GEGGVGGDAD ARRRALAEIA RRRQEQARRQ QELIKGQSCG TVKNPAHAYS ISVRS // ID E0D5C1_GRYBI Unreviewed; 1181 AA. AC E0D5C1; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 02-NOV-2010, sequence version 1. DT 03-OCT-2012, entry version 5. DE SubName: Full=TIMELESS; GN Name=tim; OS Gryllus bimaculatus (Two-spotted cricket). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Orthopteroidea; Orthoptera; Ensifera; Grylloidea; OC Gryllidae; Gryllinae; Gryllus. OX NCBI_TaxID=6999; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=20416318; DOI=10.1016/j.jinsphys.2010.04.010; RA Uryu O., Tomioka K.; RT "Circadian oscillations outside the optic lobe in the cricket Gryllus RT bimaculatus."; RL J. Insect Physiol. 56:1284-1290(2010). RN [2] RP NUCLEOTIDE SEQUENCE. RX PubMed=20637213; DOI=10.1016/j.jinsphys.2010.07.002; RA Danbara Y., Sakamoto T., Uryu O., Tomioka K.; RT "RNA interference of timeless gene does not disrupt circadian RT locomotor rhythms in the cricket Gryllus bimaculatus."; RL J. Insect Physiol. 56:1738-1745(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB548625; BAJ16356.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1181 AA; 134224 MW; 7695B97343B57A28 CRC64; MEWLVVNPLH VHGTFASVGV QVGDSYHVNK DCLSILGEVL DKLRLEDRNL WTFRRTLGFS QVIKKDLLPL LINVKNDFKI IDATIRILVN LTIPVECLVP MEVMLNTDVG RHTTVELNKL LISGKEAFVD ARSTRALVNH MKRVLEKGEK LSEEECESIN NCLLLLRNVL HIPETKNNQS TCSLQNQILW NLFSQSIDKI LIHLMTCAQK AYWGVTMVQL IAIMYKDQHV GTLQKLLNVW FEASLSESSE DNESNTSPPD QGSGGESSPM LTSDPTSDSS DNGYSQQETR LQNHSNSKME MDCKNSDSDR TSGIYHSKLS SHSDSSKGSS KSSGDSGRKV QQNLNTSRKI CAKSKKDRSG EGEIQADIKL PTSHGHNLSR TCKTDASSNV KCPSSSELSD YGYATQVENQ ESISTSSNED ECPHAKRPVH QKPHSSQKMR AINKINTNQK DVVQDKKELR RKKLVKRSRT NIMNMKALLH HVPSDEDISN LLKEFTVDFL LKGYGCLVQE LHSQLLNPKQ IIQVDTSHFF WLVTYFLKFA TQLELELEHI SPVLSFEIIS YLTYEGVNLC EQLEVATRHP GSDLKPFLRR MHLVVTAIRG FIQAVETYRK ISHLSKEDRE YLVQLQLQIG STDDLKCLFV LLLHQFNPNL QSRQYLKDLI ITNHMLLLLL ENVGKLPGYR GNIDIMEHIK QFASVEVMHQ YGLLLEDFQN NGEFTNDCVF TMMHHIGRRF RTSGLFISPN ILKTFSKIWE TDYEVCDDWS DLIEYVIHKF IDKPLQYAAA QPLQFSPMLC DALEPVPCLS DSNSLRWSKE ELENLHWFYA QSAKVPDPVG RVRDLYLENG ITNKTRIGII HQLFSQNIVN RDQYEEMTKK EMMNPIESQN EATLIFGDTK ISNAVLTTVI NRENGLHEVD ISNRSIDHVA VLRDQMLREK KGKVLMWLQK FLIEACYVKL NMDKLLSPPK KLITMEPVPH HYTLMNQSIP VVPWNSDQKK SLLYQPFMLL LHKLGFHLPA DSGKVYVRIP NFWTPDVLFN IAQKLGPISR ASLKFDEKLV KKNFMANNDS SPVLSCHVNG NQFAVQQITH SSPVIRSTPL PNSTSNWLQI VMQSKVSASS LPQRPITPPS QSVPVDFPPK TEADQMCSER GSDCSVCETA EGSVASDLTR MCVSDEEERQ ELQILSDTTI T // ID E0VIJ2_PEDHC Unreviewed; 853 AA. AC E0VIJ2; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 02-NOV-2010, sequence version 1. DT 11-JUN-2014, entry version 12. DE SubName: Full=Timeless, putative; GN ORFNames=Phum_PHUM228150; OS Pediculus humanus subsp. corporis (Body louse). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Paraneoptera; Phthiraptera; Anoplura; OC Pediculidae; Pediculus. OX NCBI_TaxID=121224; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=USDA; RX PubMed=20566863; DOI=10.1073/pnas.1003379107; RA Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., RA Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., RA Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., RA Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J., RA Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., RA Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., RA Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., RA Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., RA Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., RA Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., RA Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., RA Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., RA Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., RA Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., RA Pittendrigh B.R.; RT "Genome sequences of the human body louse and its primary endosymbiont RT provide insights into the permanent parasitic lifestyle."; RL Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS235200; EEB13198.1; -; Genomic_DNA. DR RefSeq; XP_002425936.1; XM_002425891.1. DR GeneID; 8229851; -. DR KEGG; phu:Phum_PHUM228150; -. DR VectorBase; PHUM228150; Pediculus humanus. DR CTD; 8229851; -. DR KO; K03155; -. DR OMA; SRISECT; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; E0VIJ2; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 853 AA; 99142 MW; 4D23E9F7725ADFA8 CRC64; MEDLVRKKTS AIRGKIAVIC NSLGFIHEGE YLMEPYCIEG IKELIRLLKR DDNTHISRRC LGEVNIVKHH LIHIIKNCKS DMADLFSATL RLLINVTTPA ALLYGEEIPQ DKNDRHIYLT LIEHDQSYKY SFEDVEFWNK ICCKLTNLIE INWIERSTDE TIEIERILTL LRNVLQIPRA PEDEEKIDND LTIHDKVLNA LRHSQILELL LLIVSNPNEE PFYLHLLEIF CFLLREHNPK LLAQCDLSES KMEINEDVDD LMKIREEEKS SQKFYSNTRN FKSTFVIQNI KSISNLDFVS HKSLNNLEDL AYLTLLEILH WMDCSKKPLV RALSREIKSD LFYVMEYREM TLSLFMKFEA NKFSITYLKT LIQTAHLFIK LLEEFSKSSK LIVQKISKVR KKRKGKKSKV EKNNIPINKE QIWEKICDDL QNLMASDTPI PDISPFDATL DTPIEEQKER AMKNIQKSLH LRNINEALGL FRSSRQVWPE NDCFGNENMT IEEELSALKE ICLADLLNED NVIENNKPPV SEEEEDDDDD NNTGNSSDSD EAPIKITEQD FNMQDFKRRL VHKKVVEICG LLLKNYKNNS DHVNHCAVKL LHRIGWDCNM PAMLYQASLF QTLLNIMNDK HRNYSEMNTF TINLFQKFRK HASENSIVFL ELLFWKDYSV ALEIQNKYVD YGGETMTGTK GKRSKKKLKT DENSKSKKKS KKKMEEEESF PTGLEIPDTE LEGGPTDVEL ESNDPQKEIF EMDSLKTGDS LFKEENFIEN DILIKEKIND FDDILPVKNG TEIDGTHSDG THSDDGSINN KFDDKIIFKS KKRRRLISSD DSNSDGENYV EKKKTLVIDS DSN // ID E0W227_PEDHC Unreviewed; 1076 AA. AC E0W227; DT 02-NOV-2010, integrated into UniProtKB/TrEMBL. DT 02-NOV-2010, sequence version 1. DT 11-JUN-2014, entry version 10. DE SubName: Full=Timeless protein, putative; GN ORFNames=Phum_PHUM583070; OS Pediculus humanus subsp. corporis (Body louse). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Paraneoptera; Phthiraptera; Anoplura; OC Pediculidae; Pediculus. OX NCBI_TaxID=121224; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=USDA; RX PubMed=20566863; DOI=10.1073/pnas.1003379107; RA Kirkness E.F., Haas B.J., Sun W., Braig H.R., Perotti M.A., RA Clark J.M., Lee S.H., Robertson H.M., Kennedy R.C., Elhaik E., RA Gerlach D., Kriventseva E.V., Elsik C.G., Graur D., Hill C.A., RA Veenstra J.A., Walenz B., Tubio J.M., Ribeiro J.M., Rozas J., RA Johnston J.S., Reese J.T., Popadic A., Tojo M., Raoult D., Reed D.L., RA Tomoyasu Y., Krause E., Mittapalli O., Margam V.M., Li H.M., RA Meyer J.M., Johnson R.M., Romero-Severson J., Vanzee J.P., RA Alvarez-Ponce D., Vieira F.G., Aguade M., Guirao-Rico S., Anzola J.M., RA Yoon K.S., Strycharz J.P., Unger M.F., Christley S., Lobo N.F., RA Seufferheld M.J., Wang N., Dasch G.A., Struchiner C.J., Madey G., RA Hannick L.I., Bidwell S., Joardar V., Caler E., Shao R., Barker S.C., RA Cameron S., Bruggner R.V., Regier A., Johnson J., Viswanathan L., RA Utterback T.R., Sutton G.G., Lawson D., Waterhouse R.M., Venter J.C., RA Strausberg R.L., Berenbaum M.R., Collins F.H., Zdobnov E.M., RA Pittendrigh B.R.; RT "Genome sequences of the human body louse and its primary endosymbiont RT provide insights into the permanent parasitic lifestyle."; RL Proc. Natl. Acad. Sci. U.S.A. 107:12168-12173(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS235874; EEB19683.1; -; Genomic_DNA. DR RefSeq; XP_002432421.1; XM_002432376.1. DR GeneID; 8232513; -. DR KEGG; phu:Phum_PHUM583070; -. DR VectorBase; PHUM583070; Pediculus humanus. DR CTD; 8232513; -. DR KO; K12074; -. DR OMA; LHIPETH; -. DR OrthoDB; EOG7SXW2F; -. DR PhylomeDB; E0W227; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1076 AA; 122808 MW; 989611DA66C8740D CRC64; MNFLFLKIFN HGSFSCCIKA LILNEISRKL MFEDKIIRNI RRSIAFTETL KKDFIPILVN TKDPDVIDAL IRILVNLSVP VDCLLPIEIM TKTDAGRITI SEINSFLINS KECFVDPRTT RVIIDYMKKI IEEEKRKLTE KECESINNCL LLLRNVLHIP ETKSNHCTMQ NQIVWNLFVQ NIDKVLIHLM TCKQKSYWGV TMVQLIAVMY KDQHVGTLQK LLNTWFEASL SESSEDNESN TSPPEQGSDS SPTMTSSDPT SDSSDTGGGG HKLTGNHEGS SGVPHVVQRS SSGVTECNRA GNKMIVFEEG GNSNSNCANG TERKTNIQGC NRKNKNSNRR SIDVDSGAAS LCSSEISVSS KNSSIPCQSN STIIRGKQSP DNFQHKRECF SPEMSDCGYG TQVENPELVS TSSNEEESPQ TKRPIHQKPH IQKTRYCTKQ PTLQEKKEQR RKKLVKRSKT AIVNIKAMAH HVPSNEDITH ILKEFTVDFL LKAYGPLVQV LHSQLLLPSN IVRIDTSHFF WLVTYFLKFA AQLELDLEHV KEVLSYDIIS YLTYEGVNIC ESLEIESRQE RTDLKPFLRR QHLVVTAIRE FIQATETYGK FSHLSTEDKK FLTNLQIQIS STDDLKCLFV LLLRQYDQNI HNKQYLQDLI VTNHILLFFL ENSSKLVQKK NLGFSLITHI KQFATVDVMR QYGILLEDFE SNGEYINDCV FTMMHHIGGD MNQVTSLFQP RILKTFTQIW EGDFQICDDW SDLIEYVIHR FINLTWTKDE CENLSWYFAQ SSSDNDSIST VLKLYEQSGD NPAKIPDSNR LEFLNSEKMT VDNNTADDIN YLREILIKNN RGPQLTWLQG LLIEVCYVKL VKDLNCDVNY DPITKPLEPI PHYYSHLNQS IPIVSWNAEQ ADVLLLQPFQ LLLHKLGFHL PADTGKVFAR IPSFWTVDVL FSVAQKLGPI VTSKLKFETK YLTEKLSDFK KQDKEQGNAV KNDTQSYSFS KGKHHSCLIK YNPLPNSTHH WLDLVRHGNT LPITIIESRS KECDVMDSDV ASVCSICETN RELSSSSVAS DLTRMCISDE EPMTML // ID E1ZM66_CHLVA Unreviewed; 1559 AA. AC E1ZM66; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 16-APR-2014, entry version 6. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=CHLNCDRAFT_137326; OS Chlorella variabilis (Green alga). OC Eukaryota; Viridiplantae; Chlorophyta; Trebouxiophyceae; Chlorellales; OC Chlorellaceae; Chlorella. OX NCBI_TaxID=554065; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NC64A; RX PubMed=20852019; DOI=10.1105/tpc.110.076406; RA Blanc G., Duncan G., Agarkova I., Borodovsky M., Gurnon J., Kuo A., RA Lindquist E., Lucas S., Pangilinan J., Polle J., Salamov A., Terry A., RA Yamada T., Dunigan D.D., Grigoriev I.V., Claverie J.M., RA Van Etten J.L.; RT "The Chlorella variabilis NC64A genome reveals adaptation to RT photosymbiosis, coevolution with viruses, and cryptic sex."; RL Plant Cell 22:2943-2955(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL433853; EFN53056.1; -; Genomic_DNA. DR RefSeq; XP_005845158.1; XM_005845096.1. DR GeneID; 17352451; -. DR KEGG; cvr:CHLNCDRAFT_137326; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1559 AA; 166084 MW; DDA24FC15CE29FDE CRC64; MSDLDLELLA SIASGGLGSW QQDAQENTVY VKSEDCRGKR GDEGCTRFPH TLEPATASQL APHPARRSRQ PPPAGCLRDL QRFFRYDDPE QRPAFFAVSK YNFARSDLVP LIVTYPDDYD VVYNALKVAT FLTMPSSDPL VTSNKAKQEE HMQAVREAFL AQDALAAVVG MLAEPLSRHP RMSEQDAALT QLVITFLKNL VAIPEAPPAA AAGGGAAGAS KHASRRIQTG LLERLFGDNV MDLLLLLAQH SQQRPFRSEA PVLVELFMHL FCGVDPQQLL DAPQLLEAQE RRQREEQAAA CAAAEKKRRQ QQQQQQRGGS NAFAGWGGKA ALAATTAHLP RLPALPQQRP FVPKSMLPRH VAQAAPSRHA HSGAVYVRRH TEHSSNIVLR HNPLRSELPR LPAVADAKKA PAQRKDGQAG AAGGGGGAHG GVAQPRLGAE LLVRLDAFLQ QFLEGAYDIL MTQVFREVQP GLNISRLGDA DFMHFVRLAT YCTRYVRLKE ERKLQARLQA EKDGGSAGVS PVGGAGADGT PGGADVAPGG EDEASPFSSI SATMGWDCFH WVTMLWIMLS NMEGGGRQKD HSDKNWDLQH ASVPLLKEML LALDLARVAG NAADRRAADR LQRRLLHDDL KESGLLPVLS RLIKGYNFRF QPRSHAVDLI GTLHVVLGML DRLSSAEPGG FRVRAAARQG GGRRKKPAPS PADKQPAEGE GAGEDAAAAN DDASQQQQQP GEEGAAAAAA AGGEEEQQQG SPAGSKAGSE GGDDELAQRV GRSGDPLDDD GEFDRPRAVT REVAFEAARR IRQECAQPVI VHFYAWLLQG YRTNAPFTNH AILSFLRRIA EPRQLNLEPM LYQLSVLRLF EAILSDLVIK RNPDYAELIA FAKGTVRNMF ARMVPDLSEL RQKAGEVEAN LDARFAAAEG GGGEQEADSA EQEARRERRL ALAEVKAREN AANALFVELL FWKGANVAED VRNEYNWRGL VDPQEHRRRG GRRGRGSALG DDEGSDGEQL GFASFRKKGT FTEEQAALLQ AEFEKRNGRK GCLDALVFEF GGQWKKGQIS RQLKAMGLAC GKFTQNQDER LAERYEEVRG RLDCFQLLAE ELDAGFTANQ VKFHLRKIGV VAGRKGAAPK FSDQQVKRHL QKLGIVPHKK RRQQQAQGDA AFDALAASSG DEAGGAHQRL PRSDGGSGSD SESDGGASGF GSARSELEEG SDGGGSDSDG GSSSDGGGKG APAVAAGAAT AGRVQGKAAR RQAALEALQS NAGRRKVQRQ HAREMSPELG AAALGSEDEE DGTAGDGDSI AAQQAAAAAA AASPTSSDGG GSFVSLLDSD GDGGAAAGTD AEAPASKKPK RGPAAAGADA ADNDSDGAGG SGSEDGFESA RESEPAEAGN EEEEAAPARQ RKRQPAAQKQ QQKTKKARRQ GGEEEGGRRQ QRHGEGRGTP GTKRKVAEEA AGPSSAQKRA ALDALRQRRQ QVTAAAAPAS LPPATEPLAE WRDAEEEGRG GTGAAAGVDE NAAPQAQQAG RQAQGKPAGK RRLMRGGGDG AAAAPAPVAA GLEDLEDDI // ID E2A649_CAMFO Unreviewed; 654 AA. AC E2A649; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 03-OCT-2012, entry version 6. DE SubName: Full=Protein timeless-like protein; GN ORFNames=EAG_06264; OS Camponotus floridanus (Florida carpenter ant). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Vespoidea; Formicidae; Formicinae; Camponotus. OX NCBI_TaxID=104421; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=20798317; DOI=10.1126/science.1192428; RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G., RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D., RA Wang J., Liebig J.; RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos RT saltator."; RL Science 329:1068-1071(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL437108; EFN71108.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 654 AA; 76498 MW; DAF8C6A3FB3E1D8D CRC64; MADYLSAELT ATCAVLGYFD GTDYHLDKNC LDVIKDLIRY LRRDDDTHTI RRFLGQTKLL QTDLVKILIH HVKYTELWDV LLRLLINLTS SAFVIYNEQI PTEKTTYSLY QQINLHLQDY KAALTDDNVW LTVAGRLGGL LKIDSTEREE ENELTIERIL IFIRNVLQVP PNDNDKRGDN DATIHDEILF AFHASGIVDI LLFIVSNNKE QQYHMQILEI ISLMLREQNA SQLAASGLQR NTAEKENDEA KLVALRKKEL HEKMDKVKKY AGSRHSRFGG TYIVQNMKAT GENQMICHRP YKKIETLEFG HNKKRVKRRK DKMRVQDAKV ERTSVLSVRL FLKEFCVEFL SAAYNPVMKF ARSCIINVTH GEASEITSYL WALRFFMEFN RHYKFEVKYV SETISTEVFY LVQRQMEHYY EMMITDKKKI PLWSRRLHLA LKAYQELLNT LMAMDKSIDR GVKESSKIIK NNIFYVPEYR ETILSQFLCF DETKMSRQYL VDLVTTVHIF LKMLEHFCQK GQRHLMVQQT KPKRKKAKRQ KKPAHQRIVT PVPTLEERWD IISSELSAVM QDGIIPEVVP FDATLDMPID DQKSDAMKKI QKLMRQSNLE QALGLLRTAR VIWPENDCFG RTDIPPEEEF LALREIFFAD LGGE // ID E2C3N8_HARSA Unreviewed; 215 AA. AC E2C3N8; DT 30-NOV-2010, integrated into UniProtKB/TrEMBL. DT 30-NOV-2010, sequence version 1. DT 03-OCT-2012, entry version 6. DE SubName: Full=Protein timeless-like protein; GN ORFNames=EAI_17492; OS Harpegnathos saltator (Jerdon's jumping ant). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Vespoidea; Formicidae; Ponerinae; Ponerini; Harpegnathos. OX NCBI_TaxID=610380; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=R22 G/1; RX PubMed=20798317; DOI=10.1126/science.1192428; RA Bonasio R., Zhang G., Ye C., Mutti N.S., Fang X., Qin N., Donahue G., RA Yang P., Li Q., Li C., Zhang P., Huang Z., Berger S.L., Reinberg D., RA Wang J., Liebig J.; RT "Genomic comparison of the ants Camponotus floridanus and Harpegnathos RT saltator."; RL Science 329:1068-1071(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL452328; EFN77461.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 2. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 215 AA; 25246 MW; 048DECE1B4826EB0 CRC64; MEDYLSAELT ATCAVLGYYD GANYHLDKYC LDVIKDLIRY LKRDDDTHTI RRFLGRTKLL QTDLVKILVY HVSNIELWDV LLRYDNTERE EENEMTIERI LIFIRNVLQV PANDNDKRTN NDATVHDKIL FAYHTSGIVD ILLFIVSNQK EQQYHMQVLE IVSLMLREQN ASQLAVSGLQ RSTAEKEEDE TRLVTLLQKE LQEKMNKMKK YVGSR // ID E3KJU2_PUCGT Unreviewed; 1173 AA. AC E3KJU2; DT 11-JAN-2011, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 2. DT 13-NOV-2013, entry version 15. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=PGTG_10726; OS Puccinia graminis f. sp. tritici (strain CRL 75-36-700-3 / race SCCL) OS (Black stem rust fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; OC Pucciniomycetes; Pucciniales; Pucciniaceae; Puccinia. OX NCBI_TaxID=418459; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CRL 75-36-700-3; RG The Broad Institute Genome Sequencing Platform; RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Cuomo C., RA Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Mauceli E., RA Brockman W., Young S., LaButti K., Sykes S., DeCaprio D., Crawford M., RA Koehrsen M., Engels R., Montgomery P., Pearson M., Howarth C., RA Larson L., White J., Zeng Q., Kodira C., Yandava C., Alvarado L., RA O'Leary S., Szabo L., Dean R., Schein J.; RT "The Genome Sequence of Puccinia graminis f. sp. tritici Strain CRL RT 75-36-700-3."; RL Submitted (JAN-2007) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CRL 75-36-700-3 / race SCCL; RX PubMed=21536894; DOI=10.1073/pnas.1019315108; RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E., RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., RA Cantarel B.L., Chiu R., Coutinho P.M., Feau N., Field M., Frey P., RA Gelhaye E., Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., RA Kuees U., Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., RA Murat C., Pangilinan J.L., Park R., Pearson M., Quesneville H., RA Rouhier N., Sakthikumar S., Salamov A.A., Schmutz J., Selles B., RA Shapiro H., Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., RA Rouze P., Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C., RA Grigoriev I.V., Szabo L.J., Martin F.; RT "Obligate biotrophy features unraveled by the genomic analysis of rust RT fungi."; RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS178291; EFP84567.2; -; Genomic_DNA. DR RefSeq; XP_003328986.2; XM_003328938.2. DR EnsemblFungi; EFP84567; EFP84567; PGTG_10726. DR GeneID; 10546156; -. DR KEGG; pgr:PGTG_10726; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1173 AA; 132895 MW; 5E3117321362E321 CRC64; MLCSQSSKQM CWRKAAKYTP QPTPNTNTTT TTSSSHDTTP SSVLQLIESI KKLCRQSDRD RTMVVKRSAA IKLKNAELET KRQERRLVLE PAVLGVVSAL GGYEDVLVEN KNEDQYQDQE DDDDDDEIEI EGQEKKPTPG SFRTERVYKL GDECLGCLKD LKKFWRLDEE DENRTVARIL YSSQIVPNDL LPILLSTQIE NKKDHRVALL CADLIAALTW PVDVAKELKE ACDIEDEEER RQATNIDFSS LVDGQLSYKR DIVRTGAMGP IFRLIVPVIQ KPKNERTEKD ENVISLVLHI IRNLLALRDK PASGPGIEES HLQSDFIQQL SKFGIFDLLI HMSHGSNRFD EFGQWNMIVL NIWDHLFRGV DAEDLIDAET CVGTNDTGET ISTVKASDKK LESLLLDEEQ ARKAKARKST TRHSRFGTTL SVTTGQRKFN LHSQTAITTP VELALDARKN QKKKPNRVAD EFGRPTVLKS DAMKILRGVA IEFIESGFNP FFLSILKDIQ REKAKATDAI RLLYLLGFFL DCFLKLRERE KSVGILPTSE TGHDFDLVAD LMEPECMLWV FGKIQSGLED KPMPIVEIHA AVECLIQQLL VIEGLTTSGV EDYTQVANVM LNRLYYDADT LDMVIKLMSK YTNQSLKYLE NIVHFSFVFL KILERYAGST DYMYVRKKKK ARKSKQKQTG LESADQVDGG ADEGETRNPV EDEEEAFLEA ERSGVEFAEH KFEFGKFQQR FAHEAVASTL ITYLRGYRDF TDPELMKRVV KLMYRQAVGA SAPQLFYRVS VLDTFNTMIE EKSSMPKHPV YTDLFRFIDY ILKQYFKSVG ESPFIIIEAL CNHGMRDWNR TFDSSSEDSD GMPSKASTSR KVPKLPVEIE VRPGLSWSQR LGVAVGLLVD KSKSDLVNKV QDILRTASAS RTAIVLMNDE PDDDDPQVDL ESWLQHSGKD PSEELRAQLK QPSDTSMGKF EDHRAEAGED NEFKTALARD AELHMLLRLL SWESEEEYPG HLGWTIPKGR THSELDLDIK VIDHFLINPL DHDGKSPAEL TKKKRKRRAK LPELTPAELA LDESTDSDKQ QAAKKAPRKS KKPPKITGQR STTFVTLTDN ESDAEPDRLQ SLNRSSEVNG LKRNAGMIDG QGEGENEDDG ISGVKRKPIK SRKLFIDDSD EDS // ID E3M8J7_CAERE Unreviewed; 1377 AA. AC E3M8J7; DT 11-JAN-2011, integrated into UniProtKB/TrEMBL. DT 11-JAN-2011, sequence version 1. DT 13-NOV-2013, entry version 11. DE SubName: Full=CRE-TIM-1 protein; GN Name=Cre-tim-1; ORFNames=CRE_13386; OS Caenorhabditis remanei (Caenorhabditis vulgaris). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=31234; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PB4641; RG Caenorhabditis remanei Sequencing Consortium; RA Wilson R.K.; RT "PCAP assembly of the Caenorhabditis remanei genome."; RL Submitted (JUL-2007) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS268428; EFO94385.1; -; Genomic_DNA. DR RefSeq; XP_003107564.1; XM_003107516.1. DR EnsemblMetazoa; CRE13386; CRE13386; CRE13386. DR GeneID; 9806321; -. DR CTD; 9806321; -. DR OMA; ARIECGR; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1377 AA; 160159 MW; 854C3C7FDBE40701 CRC64; MNVLIQGAVQ ALGYCEDGKY HREPDCYETI RDLIRYLRED GEDYTARIEC GRHNLVEHDL VPMVKCEDLS DDEFDIAIRL MVNLCQPAIS TMRGKAPSDR DQWKMYWELE ENLRRAKNAF TDAYFFTAIK KRIDNYFIET DFDDRDERLR LVVERIVLLI KYVFSINQDT SEGRRTRIED SSHDRVILAF LESGIDKTLM HIANQPREKE FHITILDIFA LILKEQCPEN LSKPEDDPEV STAEKKKTEE EFRKIIENHV VKETQKRKSF SRFGGSYTIK GLKGIASNST QVVFKPIQNV EKHNFLDERK QKKRVARNRR PFEIDSNTHF ASSEVRRMLR DMVIRLIETC FNRLMKSAKS TVFVQGHVIH KTSQINYFFM VKFILRFVRM SKQDPLFERI SECTGVEAFH ENNVQLTEYV ENATTLKGVE AKSYGLKAQY ALGAYNELVL LHRHIVEYGK DEGEKKRARR ALEHVVNVEE YRELPISILK KFSTSVLSNN FLRELVLTTH HYMKLVERFV KTGALKKVTK KVKVRKNHQK KSSPEDIRSE FDKMTVDSLE ALWEESKETL LQILKKEIPE MDDMNPINPQ LEVSPEAHQK FAKLFIQRSL RSRGFPAAVG LYHASRRIWK DSHSFSGLEE DATVEDELDE LYQILKMDLK KVARELKKAE EKVGSEFDRF DKMTPESIES LWEDPKVQEL LLQILNKEVP ELEDANPLNW QLEVSPETQQ QFAMLSIQRA LRSNDLPKAI GLYHSSRKLW PDENFFGAPE ITVEEEVTEL EGILKADLAE VVKEMKIAED VANKKLDDVD GDMAREYGDE MNSEDEDEAP AWKTEEIDFQ FDLYVSKYAN ADVLKWYVFL LNDFSKNGVD LNQALVKMLH RIAFDLKLPT KLYQVSLFQV LQKVNQHFTN LTKELRKTSP FYELYQFGFH LLKKFFAKFA EMGPELAIEA LFWKGPKECF EIDNGYGSWI KSKEADIKVW TEELESEIRH LYDEYTTVES REDGIDVLDF IEHNLSRARS RKQIAKKLIE FGLDLLGAKW KNLEKAQMDS VLPVGDIQKV YDEWKSGGSE GDLVDILKEK LTESLGSEIS RKKIIKQLAH MDILYEKPKK ERPLPEWDSG LIEELTGLKE QFDEIEDAEN LLGVDIVSYV MKRLSVKKPT RQVERYLASM GAKIVERPKN SSRKSEKPRK KMSEYEAFLN DSSDNEEPIR EDSEPEDDAE EPKIKKKKRA VLESDDDDDE VVTTKSKSPV DSREPSIEKS PPKNTLMSRI MNKKRKLAQL ESDSSDSEDE SQGQEKEKKE DEKEKDSDDD SDGEDDAVIY KRRYVDALLT SGSVAGGRIT RDTSEEPEEK EEEQEDPFST KIKFKRRIVM SDNEDDD // ID E3QAT8_COLGM Unreviewed; 1138 AA. AC E3QAT8; DT 11-JAN-2011, integrated into UniProtKB/TrEMBL. DT 11-JAN-2011, sequence version 1. DT 11-DEC-2013, entry version 10. DE SubName: Full=Timeless protein; GN ORFNames=GLRG_03120; OS Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize OS anthracnose fungus) (Glomerella graminicola). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Glomerellales; Glomerellaceae; OC mitosporic Glomerellaceae; Colletotrichum. OX NCBI_TaxID=645133; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=M1.001 / M2 / FGSC 10212; RX PubMed=22885923; DOI=10.1038/ng.2372; RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J., RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., RA Altmueller J., Alvarado-Balderrama L., Bauser C.A., Becker C., RA Birren B.W., Chen Z., Choi J., Crouch J.A., Duvick J.P., Farman M.A., RA Gan P., Heiman D., Henrissat B., Howard R.J., Kabbage M., Koch C., RA Kracher B., Kubo Y., Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., RA Moore N., Neumann U., Nordstroem K., Panaccione D.G., Panstruga R., RA Place M., Proctor R.H., Prusky D., Rech G., Reinhardt R., RA Rollins J.A., Rounsley S., Schardl C.L., Schwartz D.C., Shenoy N., RA Shirasu K., Sikhakolli U.R., Stueber K., Sukno S.A., Sweigard J.A., RA Takano Y., Takahara H., Trail F., van der Does H.C., Voll L.M., RA Will I., Young S., Zeng Q., Zhang J., Zhou S., Dickman M.B., RA Schulze-Lefert P., Ver Loren van Themaat E., Ma L.-J., RA Vaillancourt L.J.; RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi RT deciphered by genome and transcriptome analyses."; RL Nat. Genet. 44:1060-1065(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG697339; EFQ27976.1; -; Genomic_DNA. DR EnsemblFungi; EFQ27976; EFQ27976; GLRG_03120. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1138 AA; 130754 MW; 77E57C049BB21CC6 CRC64; MEMPDGTTDI VHPEVRAHIN SLVSALGGTS ADDDGRYKLG DDALEVLRDL KKWIRFYDEK TNRMDVARCI ADANLVEGDL LHILASWPEN DTNNKFKARV ALACFEIMVP LTWPMEREAE RMTVNHHRHM PVLELAQVGY KRAIINFDSA QILNTAVRAA LPSMAIAIGD RTPRDQGVIK LVLFFLRNIA MITPSPGIQY DGDETQISRS TTIDAFSFQD IFAVLLMIAS NMGEDFRTED VILMEVIYHL VKRVDIKQLF MDERQLNKSK AQELSSMMSK EAAMRNAYNR KGPTRHNRFG TMVWMQRDDG RVSTITGQDA LADSATRQKK LDESKTFKPP RRSRKEELES KDLGAPVKLN ARANDQLRNF VEDFLDAGFN PLFEHVRKSL DREASHVLSY HRRQFMYLVA WFLEAERIRR NSKRESKTPG TAEEVSSFNI VAGVLNQPMF VTLTKTMHDS WEHKDWPTLT AAMRCFTQIL LTVQEMTESG HEDDQEIAEN TLSRLFYEDS THDLIANVVR QYKEQGFEYL DSATELTHHF LRILEAYSKQ NVDMQVRSRK RTRRKKKAAA QDSTGVDTLD EDNDDSANDE ANAEKTSKER KFDFHRFASR FTPQGVVDTF VAFTKFYRDL DDSQLKRAHR YFYRVAFKQE MSVMLFRVDI VHLLYSMIKG PEPLDKSSTM YKEWEELSKQ ILRRCMRKIE QRPELIIELL FSKINSTVFF LEYGYEKQTV STSHARPAAE LEFKHTEERD RQIAIVVGAL LDKNQADHIA WVKSMLESVE SERRAWAAAN EVIPSVERTE TAEDAPTDET ANLPPPFTVR PDSDARRTAL FKNAHLRLFM KLVGFERLAP TLEETPQSLW ILPAQVTAED LHESLGFINK AEFDPPVFED GRGAEDQLRR KKVARKRVEY DDDEDEDLDD GFIFDPLGPT AHKAIDEPAS KKTKRRRRRK GSEEGEEPND SELEEKAKKR REREREKARK VKSQAYVHAS DDETDEEYDR EFFLREEAQR LRLARIVEKV TLSETTKRPL VDLDDNDDDL LDLTRATQST RESADVDMDG GSEAEQDGNN RTPLTSSPSS SQGTMTNKRR RLSPEEGGHG QKEASADSEN DEEDAPVTAA RSRQRTRGGF VMDSSDEE // ID E3RKF4_PYRTT Unreviewed; 1166 AA. AC E3RKF4; DT 11-JAN-2011, integrated into UniProtKB/TrEMBL. DT 11-JAN-2011, sequence version 1. DT 13-NOV-2013, entry version 11. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=PTT_08711; OS Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) OS (Drechslera teres f. teres). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; OC Pleosporaceae; Pyrenophora. OX NCBI_TaxID=861557; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=0-1; RX PubMed=21067574; DOI=10.1186/gb-2010-11-11-r109; RA Ellwood S.R., Liu Z., Syme R.A., Lai Z., Hane J.K., Keiper F., RA Moffat C.S., Oliver R.P., Friesen T.L.; RT "A first genome assembly of the barley fungal pathogen Pyrenophora RT teres f. teres."; RL Genome Biol. 11:R109.1-R109.14(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL533633; EFQ93803.1; -; Genomic_DNA. DR RefSeq; XP_003298109.1; XM_003298061.1. DR EnsemblFungi; EFQ93803; EFQ93803; PTT_08711. DR GeneID; 10522565; -. DR KEGG; pte:PTT_08711; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1166 AA; 133061 MW; C9B00D1E0D8A5C27 CRC64; MPQTTLDDWA KDTVNPEVRA HVSSLISALG GIGDDGTYSL GHDALLCLKD LRKWLKFADQ QNNRRDVARC MAEANLVKGD LLEILAKISP TAMDSAWKHK IAVATLELLV PLTWPFEIDP TEATVNHHRH GPYIQLAQIG YKRAILQFDR DRILQTTVKI ALPSMAVPLR ERLPRDEGII RIALYFIRNI AMLSPPNSAP MDIDEAEVSR SATIDTFQEQ DIFQVLLSIA SSIGEDFVSQ DVIVLEILFF LLKGIDAEKL FMEDKKLNTK NADELKSLIQ KEKAMLAGYA RNAPTRHNRF GTMIWVKRDD EKVTTISGQD VLGKAQASMQ KMDATKKWNK PRRPGRKQDG SEEREEFDLP VSLSTSARKH IKAFVEEFLD SSFNPLFLHL RKAIERETER VETRHSRQFF YLVSWFLKAE CARRRTMKER AADPKSPEVL SAEDESYGLV AEVMNQETFI LLNRFMQTSQ DEKAWRDLNA GLKCFTQILL TVHEMSESAL EDDQEIAENI QNRIFYEEST HDRIVMILRS YKDQGFGYLD AVTELSHVFL RMLERYAKQN VDMQIRSKRR ARNIKKKKAD KQGEEGEEEG HVSETEDIQQ AQKTVSERKF DFTRFSAKFV NQSSVDTFVA FTKYFNDLNT EQLKRAHRFF HRVAFKMELG VLLCRVDILQ LFNKMMKGPG GLDPESPVYR EWDDFVRHFF RQVVKRVQER PELVVEMLFS KIPATIFFLE HGYDREVTVK APRAPAELEV KPGMELPEQI GVAVSVLVNQ SKSDGIRWVR EVLTSAAEER KAWEEAEEAQ KILTADVQPA DGDAAAENTE AEPTKPPSIL IKHDTEERRI AMFKDNKLRL LMTLVGFERL GEHHDPDATW IVPSSLTSAQ LQEAIDLIRK FEFDPPTYED GKAPEDMLRS KTTAARRSTR RAEFDDDSDG IDHQSEEDHG EYAQGGATTR EADGPRKKLK RRRRERTPHE LDDDEKERRA EARRKKELEK QAAALSTMYV HDSDDEDWDA EKDAAFFARE EALRQENLKA YKNSHIIGTV EPVASKKRKA DAPAKKTKRR KAPFDDSDQE MEDAESSRAQ SETAGDILDD DENEETTDTP LSSQHAGAAA VSEAGTPRKP LENASKTSDV AMTNADTDDD EDDMPVARRP AARNMRAGFV IDSDSE // ID E4V2T4_ARTGP Unreviewed; 1165 AA. AC E4V2T4; DT 08-FEB-2011, integrated into UniProtKB/TrEMBL. DT 08-FEB-2011, sequence version 1. DT 13-NOV-2013, entry version 9. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=MGYG_07315; OS Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum OS gypseum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; Arthroderma. OX NCBI_TaxID=535722; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4604 / CBS 118893; RX PubMed=22951933; DOI=10.1128/mBio.00259-12; RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W., RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E., RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I., RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., RA Summerbell R.C., Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., RA White T.C.; RT "Comparative genome analysis of Trichophyton rubrum and related RT dermatophytes reveals candidate genes involved in infection."; RL MBio 3:E259-E259(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS989828; EFR04308.1; -; Genomic_DNA. DR RefSeq; XP_003170071.1; XM_003170023.1. DR GeneID; 10025306; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1165 AA; 132500 MW; 69ECB3BB86088730 CRC64; MDVEPFVAQP GDQVVDPEVR SFIYGLVTAL GGSANDEAGR YMLGDDALGC LRDLKKWLRF YDEKLNRLDV ARCIAESNLV NGDLIQILAL WDDVKPTDKY KSRISLACLE LLVPLTWPVE IHSEMTVNHH RHTPYLQLAQ ISYKKGILGH ASKSILRSII RIGLPSITTP RAERSSRDEG ILKLVLYLFR NVAVLGVTAN LAVEGDEDEA SRSMTISAFH DQDVFALILT LCSNIGEEFT FQDVILLEIL FHLIKGVDVH QLFMDDNQRS ATRTDELKGL MDAESNLNRD RSKNAPTRHG RFGTMIWVKR DNEKMSSVSG QDVLLNDQAA FDKMDKTKKW NKPRGKRPVV DETSNNFNVQ VHLTSSALNY LRLFVEEFLD SGFNPLMTSI RKAMERESDR LGETSSRHFF FVSSWFLSAE RARREQQEEA RQNATGSARN IEPDSFALVA SVLNQETFIA LNRYMQTSLD NKEWQDLNAG MLSFTQTLLT VQEMSKSSLE DDQEIAENIL SRIFYEESTH DRILSTLRGY KGQGFWYLDA CTELAHVFLR MLEQYSKQNV DMQVRSKRIS RRKKKAQNQG QENQEEEDGG FGNSEDEEAN DRAEAVRNVA ERSFDFKRFC NKFCTQNSVN TFVALTSYYR DLSAEQLKRA HRFFYRVAFK QDVSVLLFRL DIIALFTRMI KGPDGLLSSR PEFREWEELV RQILKKMFRK IDERPELITE LLFSKIPATV HYLEYGHEKQ TVSVASRPAV ELEVKHNYTR TADEKLRIVI SVLVADNCED LVRWLYGVID NALKDRKSWE LADLARGTQD ATDMTDITSS TPAIEVSAPG EKHKTAMFKN GHLRLLFTLA GLELAGEDVL GTPWSIPGSI SSTELEETRS SIQKHCDDPG TEIDGVDPHK LIHRKRVAGK AMNDEATAQV DFGNDSEGEE LGLDEVLFPP NPRSKSKVLK ELKQKRRKKA GDDEDNQLDE ETLNARRLAR EQNALERQRK IKSSLFVNAS DDETDDEADQ EFFAREAERR KKQAQRVEEA MDIDGFGNNE LDNTTKKAKG KRKQAISNDS DDEDENGGHR KRARSEEDEE SGGPPGRKAQ TPPTSTEDDL IFDMGEKSPA PIFQWTSTAV DRPSKPMATA EHNPDDDDED DEPVMTTRTR RPKVMAGFVV DSDSE // ID E4YSM5_OIKDI Unreviewed; 224 AA. AC E4YSM5; DT 08-FEB-2011, integrated into UniProtKB/TrEMBL. DT 08-FEB-2011, sequence version 1. DT 06-MAR-2013, entry version 4. DE SubName: Full=Whole genome shotgun assembly, allelic scaffold set, scaffold scaffoldA_956; DE Flags: Fragment; GN ORFNames=GSOID_T00032409001; OS Oikopleura dioica (Tunicate). OC Eukaryota; Metazoa; Chordata; Tunicata; Appendicularia; Oikopleuridae; OC Oikopleura. OX NCBI_TaxID=34765; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21097902; DOI=10.1126/science.1194167; RA Denoeud F., Henriet S., Mungpakdee S., Aury J.M., Da Silva C., RA Brinkmann H., Mikhaleva J., Olsen L.C., Jubin C., Canestro C., RA Bouquet J.M., Danks G., Poulain J., Campsteijn C., Adamski M., RA Cross I., Yadetie F., Muffato M., Louis A., Butcher S., RA Tsagkogeorga G., Konrad A., Singh S., Jensen M.F., Cong E.H., RA Eikeseth-Otteraa H., Noel B., Anthouard V., Porcel B.M., RA Kachouri-Lafond R., Nishino A., Ugolini M., Chourrout P., Nishida H., RA Aasland R., Huzurbazar S., Westhof E., Delsuc F., Lehrach H., RA Reinhardt R., Weissenbach J., Roy S.W., Artiguenave F., RA Postlethwait J.H., Manak J.R., Thompson E.M., Jaillon O., RA Du Pasquier L., Boudinot P., Liberles D.A., Volff J.N., Philippe H., RA Lenhard B., Roest Crollius H., Wincker P., Chourrout D.; RT "Plasticity of animal genome architecture unmasked by rapid evolution RT of a pelagic tunicate."; RL Science 330:1381-1385(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN655230; CBY38464.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 224 224 SQ SEQUENCE 224 AA; 25930 MW; 2CB6EB2AB2BF05FA CRC64; MDLLFMNIDL LSLTSEIGYV EDGVYIPDEN CSETLTQINE LVDEDDDFGS TRQQLASSNI FETDLLPLLE HQNGEDTIFE PLIKFLSAIT CPLSIKQEDK VHTVNKKIMD KHQENFKRYF ARAVYWVRVR EQIEKGLNRE FTKTLKDVTG YSFNLVRNLI DIESEAAYER TLCCFADSGI AKLIQFVGIE EQLNIWHLHV TEIIYSLYKD IMQESLVVDT SMDP // ID E5S9A6_TRISP Unreviewed; 1269 AA. AC E5S9A6; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Timeless protein; GN ORFNames=Tsp_00327; OS Trichinella spiralis (Trichina worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia; OC Trichocephalida; Trichinellidae; Trichinella. OX NCBI_TaxID=6334; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ISS 195; RX PubMed=21336279; DOI=10.1038/ng.769; RA Mitreva M., Jasmer D.P., Zarlenga D.S., Wang Z., Abubucker S., RA Martin J., Taylor C.M., Yin Y., Fulton L., Minx P., Yang S.P., RA Warren W.C., Fulton R.S., Bhonagiri V., Zhang X., Hallsworth-Pepin K., RA Clifton S.W., McCarter J.P., Appleton J., Mardis E.R., Wilson R.K.; RT "The draft genome of the parasitic nematode Trichinella spiralis."; RL Nat. Genet. 43:228-235(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABIR02000724; EFV58647.1; -; Genomic_DNA. DR RefSeq; XP_003376108.1; XM_003376060.1. DR EnsemblMetazoa; EFV58647; EFV58647; EFV58647. DR GeneID; 10901583; -. DR KEGG; tsp:Tsp_00327; -. DR CTD; 10901583; -. DR KO; K03155; -. DR OMA; ANINVER; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1269 AA; 145756 MW; 4D82CCA3B256A82C CRC64; MDKVSTDLQV AVTSIGFKDA ELYLKEPDCL ETLKDLSHFL RHDDSECTAR KFIGSSNIVE NDLVPLIILY SDDAALFDET LKLLVNLTQS ADLFFFNDNA DIFVNQAKQL MVKHLQISQH AFTDERFFKK WQDRGEGETM IIQRILVLTK QVLSVPLATV DTICSYSSTC HDRIIKAIES SGFGDILLDM STSHANREFH ATILEIAVAM LKYQKVEDVV KAVPDSNSLQ QDEEERLKAK LQNSQYKLHG YSERPSNFCG SYTVAGVKAI GGLNDIVVNK PVTSESSLSH DSKKKRKAVA KNRAPIETTL EPVKRSSPTV RIFLKRFCLR FIKKAFVPVM NNVYQFLHRA EGESGLKMEQ CYFWALRFFL HFYRYFYQNL GSAWRVISIN LFHFVQERIL SNIEKMKVDK PNARLYGRRA HHALKTYAEL LSVLWLMSQK VGDEAAVVAS DIQRCLFRVV EYREVFINLL KLYNPTCLSN LHGGSLVVQR KLKRIKKKKK NRSDSDDKEN HSENENNEAD QDAKKAELWS RLSLELDQIL ILNSNLPADV VPFDATTDLS EIERQTTAKQ RIQKALLAEH IAEALALLRA SRELWPTEQE FGTAETEIEV LKSALYSAEL EDSENDVAVF GLEDNDADCM EDEELCENDE DEENGITEVI REVHFQITDF IQRLANPIYL RWYVWLLKDF RKNSNNVNSC IVSMLSRVAF DLNVPPLLYQ ASLFRIFQQV DELNKANINV ERYRELTAFG KRLLKHFFED AKDNPNIYVE ILFWKHFKES YEISYGYGSY DKKGASSKVI ASAILESKIE NLFQKFLEEP EKNTTDVADY IMENLDNTAS RRTIVRALRG LNLPFENYLL KKKSSKSSTK WAWSVEEEEE LKSLYENFKN SKDVINMICQ NLSGAHSKRA VSKKLNELGL EVLRRHKRKM NEMLDRSESE SDESNMRLLP NLEQHVFSDE ESSNEEVSNS AKTFQDFNVL SPTLAGAIKC IEQDLSNTVV HWVRECILEA INNQLKEDFI PLIPECEEHY RIIQELEFSK TLIKLGFLSP KMTNQRYWCI PSSASIDRLK LIAEQLNNSE RMDIQIDSYS TDSKCQPESE NKNISRHELI SNKKNFEKLR KLYAAKRQRN SVFSADDAFD IATSDHMKSP ISKRPKGSGM EDILDFEQET EEMDINRQSD TTKVVSNNSA ALKFKRSAFI ESSEDSEDEM STAKCEQAAT STQAEHSDSE LKLSIELRKV LAISDDDDDL PISSVEKSSH VMMTFSDED // ID E6R8R0_CRYGW Unreviewed; 1169 AA. AC E6R8R0; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 13-NOV-2013, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN OrderedLocusNames=CGB_F6260W; OS Cryptococcus gattii serotype B (strain WM276 / ATCC MYA-4071) OS (Filobasidiella gattii) (Cryptococcus bacillisporus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella; OC Filobasidiella/Cryptococcus neoformans species complex. OX NCBI_TaxID=367775; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=WM276 / ATCC MYA-4071; RX PubMed=21304167; DOI=10.1128/mBio.00342-10; RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G., RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., RA Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., RA Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A., RA Meyer W., Carter D., Schein J., Krzywinski M., Kwon-Chung K.J., RA Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F.F., Siddiqui A., RA Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A.; RT "Genome variation in Cryptococcus gattii, an emerging pathogen of RT immunocompetent hosts."; RL MBio 2:E342-E342(2011). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=WM276; RA D'Souza C.A., Kronstad J.W., Taylor G., Warren R., Yuen M., Hu G., RA Jung W.H., Sham A., Kidd S.E., Tangen K., Lee N., Zeilmaker T., RA Sawkins J., McVicker G., Shah S., Gnerre S., Griggs A., Zeng Q., RA Bartlett K., Li W., Wang X., Heitman J., Stajich J.E., Fraser J.A., RA Meyer W., Carter D., Schein J., Krzywinski M., Kwong-Chung K.J., RA Varma A., Wang J., Brunham R., Fyfe M., Ouellette B.F.F., Siddiqui A., RA Marra M., Jones S., Holt R., Birren B.W., Galagan J.E., Cuomo C.A.; RT "Genome variation in Cryptococcus gattii, an emerging pathogen of RT immunocompetent hosts."; RL MBio 0:0-0(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP000291; ADV23165.1; -; Genomic_DNA. DR RefSeq; XP_003194952.1; XM_003194904.1. DR GeneID; 10190665; -. DR KEGG; cgi:CGB_F6260W; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1169 AA; 133148 MW; 7258005E10D426CF CRC64; MDLPDSPPPL DAPSPPHFLD APQDRWNVFY PAVQTLVNAL GGYEEVETPP DSGIFETVYR PGDSVLGVLK DLKKLWRKDD EDDERTVARC MHKAELMKEL VAILVECAER GEWGRKVALV ACDLIAALTW PIDVAQELKE IEDEGPVVTD YASLLRAQLE YKALFLKTTK PLKSILSLMV PSLAKPRKDE KDSRIISLGL HVVRNLLAIK DAVAEGTATG EKEEFAHLQS DLITQLDSLT YLQLFLSLCS CADKTDLNPF NVILLDILHL IFRGIRPTEL AQDQERVPID GLAKLLEKEK KQKALNSRVG STRHSRFGTT ITVKTAEQRV VLHRQTAIIE NPGKILDMTK KKKAVAAKSM DDLTVYVNLG SDAMVVLQSF SKSFLEISYN TFIESILRDI RMERTKIRPS DNIRVFYLSS FFIEYLLLLR HKLVEKGDSR RLEELPLGLV AQIAEMDSVK WLFARLRICW DDKPKAWTEL QACIDCFTQI LLLIDDMSTS TNEEDVEVAE ILQHQLYYNY DILDSALAVV REYKNQSVAY LDSVIHFAYV LLRMLEKYSK TKAFMFIRKR KNTHKKRKER QAASQANADR EQQGESRRIP EEYEDEEEGA FDPDQDGPSY AEHAFTFQSF EKRFAQEAVV NTLLTYLERF LEFDGPEPMK RVVGLMHRQV VKAHAESLYF KVSTLIVFRR ILDKKHALPA APSSRDLITL ITYILRKFFK HVAKEPFTLV EALSSKSRGK WKAIREGGND DGDDGMTGQR GRIKEKMSIA FAIIWGDGHG YLIKWIVEIL EQVLAAKQEI VLTTDGGING DEDEEDEDGN VRVRRFGRPS DEAISKFTQF DLQPEENEQI EAVTSNPHFR LMLKLLSFDL PPPPTELDFV EDISSEELAL AREKSDSAWF LPANVLPSNI EASIGALKQY MEEPPTLDDD PRKLLRRKTR APRRRRRSPS VESYDSETGE TRPDRPHKKN SHHKRAKKAV ETQNYKSAAF IEDSDDEDPE ATRLFFENEE RLRREMDELA AQGGHAMLQR GVKRKRGKKK DGKDPNDVGV SSLTADVSGS EDENTLEGDA EDQDEVFRTI TITTEQKAQM ERQKAQLTAI REMANDSDDE DGSDDDSELR AKRRAMESSE SGMPFFEGSD NDDEDDEPFA KPSAKVRRRV IDPDEDDES // ID E7A1J3_SPORE Unreviewed; 1267 AA. AC E7A1J3; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 16-APR-2014, entry version 10. DE SubName: Full=Related to TOF1-topoisomerase I interacting factor 1; GN ORFNames=sr14009; OS Sporisorium reilianum (strain SRZ2) (Maize head smut fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Sporisorium. OX NCBI_TaxID=999809; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SRZ2; RX PubMed=21148393; DOI=10.1126/science.1195330; RA Schirawski J., Mannhaupt G., Muench K., Brefort T., Schipper K., RA Doehlemann G., Di Stasio M., Roessel N., Mendoza-Mendoza A., RA Pester D., Mueller O., Winterberg B., Meyer E., Ghareeb H., RA Wollenberg T., Muensterkoetter M., Wong P., Walter M., Stukenbrock E., RA Gueldener U., Kahmann R.; RT "Pathogenicity determinants in smut fungi revealed by genome RT comparison."; RL Science 330:1546-1548(2010). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FQ311472; CBQ73350.1; -; Genomic_DNA. DR EnsemblFungi; CBQ73350; CBQ73350; sr14009. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Isomerase. SQ SEQUENCE 1267 AA; 142035 MW; BAF9569B3756263E CRC64; MADENDYYSD DLQGDEGFLT DDSEERYGDG YGEPSRHYDD DPEDNVAALE EIRETAMELC WQVGDYDYAD EDSAEQDNKF YTGWTRGPQA LSALRSLRKL WKLDDDDPTR KVARAFVDCT VLPNFLLPAL LESAGKDPPM GDAIVLACTD LLAAMTWPFD SAAELRELSK QGLDYDDLDE ITKLDQKLIV YKSAILRCMS LDKQHDVLGV VMRYLLLPKL TTKKHQRTSL ENGIISMCLH LIRNLLAIRD PITTSLSSVE QLSYANLQSE LILSLKKHHI LDALLMLASS AETSNFNDWN AIASECIFHI FVGTKVKEIA EVTSGSASRS ITDTSEAART SSRTAATATS SGSSSALAES LAMEAKIKRA SASGTIPTRH SRFGTTINFV GPDGLRRVAR NQSALAKSVA QLADEAMHKG KRRAQRRKNA QEQGAPKLKA KWTADAALVL QDWADAFVQA GFEPLAKSVL KDIRSERDKL GDLDVARVRI MQLGTFFLEY FLSRRAAAAQ RRKAAGTTAP AQPTLTQETA DLLEPQQHHE AEKAQSEQPA EGADGEWPFE LVSQWLEPWA FRMVLVRTIQ AQESKAWLEF VAAVQLWTVL LRLVDELASS KKESERDVAE GLQAEFYYMS ETLDACHAVV RSYTAQSFAF LETIIGFAYY MPKMLERYAS NRDHMYVQAK KQVRRSRQDG DLDADEDEAA QIKEQLKETR SEREFRFADF QRKLATKQLT TACSHYLSYL SGWHDYGDTD EQLNKLVTVM HRIAIKANDY RQFFLAGLRS NLRSVISGNA MGILEARAPT SAPTLKKLID YILRKFSKLS PEEQSIYDTG KRPPRQPKPP RMPAEIAVRP GMAPDEEIGV AVGLLLKKEK MQAVLWVKSA LEMASAMRTE LVARHEEDGT RRQSESSTSI LGEDAADDDS GAMLLGELEK QNESPVERFQ PFELAYRGND ELRTDASLLP ELKLLCRLVG LEANDDELVH WKWTVPKEIL PEHLDEKVEA IERFIREPLD THGRELTALV MRMRKPRVGG EDNSDVTNSA DLPDGWNGAL SESDEDGDYF DRVRASRSLV TSEGAAADGG LLRSSGAKKR SKPTANRGGR KQMRRTEQEF LNDSDEEWAF AMAEIEHDDE ERKAAEDSSS DEHGDGIDER ETPPTSSVVD DVQEEQAVDD AGKQSALQAL RTAQQKRSKT TKEPLQDARQ RTNRRVDTKR LFLADSDEEE ALFSSQELEQ NKTELGQPLA PTNLSSGFYA KKRSRLAILD DEDEDEE // ID E7EWS5_HUMAN Unreviewed; 705 AA. AC E7EWS5; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 11-JUN-2014, entry version 22. DE SubName: Full=Protein timeless homolog; GN Name=TIMELESS; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=17081983; DOI=10.1016/j.cell.2006.09.026; RA Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., RA Mann M.; RT "Global, in vivo, and site-specific phosphorylation dynamics in RT signaling networks."; RL Cell 127:635-648(2006). RN [2] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=16964243; DOI=10.1038/nbt1240; RA Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; RT "A probability-based approach for high-throughput protein RT phosphorylation analysis and site localization."; RL Nat. Biotechnol. 24:1285-1292(2006). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16541075; DOI=10.1038/nature04569; RG Baylor College of Medicine Human Genome Sequencing Center Sequence Production Team; RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., RA Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., RA Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., RA Nazareth L.V., Scott G., Sodergren E., Song X.Z., Steffen D., RA Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., RA Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., RA Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., RA Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., RA Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.V., RA Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J., Santibanez J., RA Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., RA Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., RA Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., RA Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., RA Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., RA Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., RA Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., RA Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., RA Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., RA Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., RA Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., RA Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., RA Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., RA Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., RA Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., RA Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., RA Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., RA Perrin W., Pickens A., Primus E.L., Pu L.L., Puazo M., Quiles M.M., RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., RA Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., RA Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., RA Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., RA Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., RA Kucherlapati R., Weinstock G., Gibbs R.A., null.; RT "The finished DNA sequence of human chromosome 12."; RL Nature 440:346-351(2006). RN [4] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=18669648; DOI=10.1073/pnas.0805139105; RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., RA Elledge S.J., Gygi S.P.; RT "A quantitative atlas of mitotic phosphorylation."; RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). RN [5] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19413330; DOI=10.1021/ac9004309; RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., RA Mohammed S.; RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in RT a refined SCX-based approach."; RL Anal. Chem. 81:4493-4501(2009). RN [6] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19690332; DOI=10.1126/scisignal.2000007; RA Mayya V., Lundgren D.H., Hwang S.I., Rezaul K., Wu L., Eng J.K., RA Rodionov V., Han D.K.; RT "Quantitative phosphoproteomic analysis of T cell receptor signaling RT reveals system-wide modulation of protein-protein interactions."; RL Sci. Signal. 2:RA46-RA46(2009). RN [7] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=20068231; DOI=10.1126/scisignal.2000475; RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., RA Mann M.; RT "Quantitative phosphoproteomics reveals widespread full RT phosphorylation site occupancy during mitosis."; RL Sci. Signal. 3:RA3-RA3(2010). RN [8] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21269460; DOI=10.1186/1752-0509-5-17; RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., RA Burckstummer T., Bennett K.L., Superti-Furga G., Colinge J.; RT "Initial characterization of the human central proteome."; RL BMC Syst. Biol. 5:17-17(2011). RN [9] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21406692; DOI=10.1126/scisignal.2001570; RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., RA Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., RA Blagoev B.; RT "System-wide temporal characterization of the proteome and RT phosphoproteome of human embryonic stem cell differentiation."; RL Sci. Signal. 4:RS3-RS3(2011). RN [10] RP IDENTIFICATION. RG Ensembl; RL Submitted (NOV-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AC024884; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR ProteinModelPortal; E7EWS5; -. DR PRIDE; E7EWS5; -. DR Ensembl; ENST00000554616; ENSP00000450848; ENSG00000111602. DR HGNC; HGNC:11813; TIMELESS. DR OrthoDB; EOG7WDN1T; -. DR NextBio; 35500846; -. DR ArrayExpress; E7EWS5; -. DR Bgee; E7EWS5; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 1: Evidence at protein level; KW Complete proteome; Reference proteome. SQ SEQUENCE 705 AA; 80527 MW; 75AB7E5E0B57ADD0 CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHHQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EEQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADF AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL NTVPRTRKQI IHHLVQMGLA DSVKDFQRKG THIVLWTGDQ ELELQRLFEE FRDSDDVLGH IMKNITAKRS RARIVDKLLA LGLVAERREL YKKRQKKLAS SILPNGAESL KDFCQEDLEE EENLPEEDSE EEEEGGSEAE QVQGSLVLSN ENLGQSLHQE GFSIPLLWLQ NCLIRAADDR EEDGCSQAVP LVPLTEENEE AMENEQFQQL LRKLGVRPPA SGQETFWRIP AKLSPTQLRR AAASLSQPEE EQKLQPELQP KVPGEQGSDE EHCKEHRAQA LRALLLAHKK KAGLASPEEE DAVGKEPLKA APKKRQLLDS DEEQEEDEGR NRAPELGAPG IQKKKRYQIE DDEDD // ID E7FGL0_DANRE Unreviewed; 1278 AA. AC E7FGL0; DT 08-MAR-2011, integrated into UniProtKB/TrEMBL. DT 08-MAR-2011, sequence version 1. DT 09-JUL-2014, entry version 26. DE SubName: Full=Uncharacterized protein; GN Name=timeless; OS Danio rerio (Zebrafish) (Brachydanio rerio). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; OC Cyprinidae; Danio. OX NCBI_TaxID=7955; RN [1] RP IDENTIFICATION. RC STRAIN=Tuebingen; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Tuebingen; RX PubMed=23594743; DOI=10.1038/nature12111; RA Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., RA Muffato M., Collins J.E., Humphray S., McLaren K., Matthews L., RA McLaren S., Sealy I., Caccamo M., Churcher C., Scott C., Barrett J.C., RA Koch R., Rauch G.J., White S., Chow W., Kilian B., Quintais L.T., RA Guerra-Assuncao J.A., Zhou Y., Gu Y., Yen J., Vogel J.H., Eyre T., RA Redmond S., Banerjee R., Chi J., Fu B., Langley E., Maguire S.F., RA Laird G.K., Lloyd D., Kenyon E., Donaldson S., Sehra H., RA Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M., RA Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J., RA Clee C., Oliver K., Clark R., Riddle C., Eliott D., Threadgold G., RA Harden G., Ware D., Mortimer B., Kerry G., Heath P., Phillimore B., RA Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S., Pelan S., RA Griffiths G., Smith M., Glithero R., Howden P., Barker N., Stevens C., RA Harley J., Holt K., Panagiotidis G., Lovell J., Beasley H., RA Henderson C., Gordon D., Auger K., Wright D., Collins J., Raisen C., RA Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D., RA McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S., RA Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E., RA Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., RA Babbage A., Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., RA Wray P., Ellington A., Matthews N., Ellwood M., Woodmansey R., RA Clark G., Cooper J., Tromans A., Grafham D., Skuce C., Pandian R., RA Andrews R., Harrison E., Kimberley A., Garnett J., Fosker N., Hall R., RA Garner P., Kelly D., Bird C., Palmer S., Gehring I., Berger A., RA Dooley C.M., Ersan-Urun Z., Eser C., Geiger H., Geisler M., RA Karotki L., Kirn A., Konantz J., Konantz M., Oberlander M., RA Rudolph-Geiger S., Teucke M., Osoegawa K., Zhu B., Rapp A., Widaa S., RA Langford C., Yang F., Carter N.P., Harrow J., Ning Z., Herrero J., RA Searle S.M., Enright A., Geisler R., Plasterk R.H., Lee C., RA Westerfield M., de Jong P.J., Zon L.I., Postlethwait J.H., RA Nusslein-Volhard C., Hubbard T.J., Roest Crollius H., Rogers J., RA Stemple D.L.; RT "The zebrafish reference genome sequence and its relationship to the RT human genome."; RL Nature 496:498-503(2013). CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AL954313; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; NP_001265529.1; NM_001278600.1. DR UniGene; Dr.57903; -. DR Ensembl; ENSDART00000112417; ENSDARP00000099210; ENSDARG00000078497. DR GeneID; 325855; -. DR KEGG; dre:325855; -. DR CTD; 8914; -. DR ZFIN; ZDB-GENE-030131-8978; timeless. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; E7FGL0; -. DR TreeFam; TF312802; -. DR NextBio; 20809520; -. DR Bgee; E7FGL0; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1278 AA; 147903 MW; 9CD111621C9CC562 CRC64; MDLYMMNCEL LATCSALGYL EGDVYHKEPD CLESVKDLIR YLRHEDDARD IRQQLGAGQI LQNDLLPIIT QHTQDKPLFD ACIRLMVNLT QPALLCFGKI PDDPAFRHHF LQVTSYLQAY KEAFADEKVF TVLSETLYNL LQLDWEQRDE EDNLLIERIL LLVRNVLHVP ADPYEEKNVD DDASVHDKLL WAIHISGLDD LLKFLACAQS EQQWSFHILE IISLMFRDQT AELLVSAGQM RSAQEKQKDM QELELLRQKE TAEKRSRTLM RGTRHSRFRG SYVIEGLKSI GENDVVYHQG LHNFKSYSHD LGKAVRRVPK RKQMAKDSDS HRRSALNVRL FLREFCIDFL ENCYNRLMYL VKEGLIRERA QQHDETYYMW ALTFFMAFNR LQNFKPDVVS ETISIRTFHF IEKNITNYYE MMLTDKSDAT SWSRRMHLAL KAYQELLLTV NEMDRSKDEN IRHSSSVIKS NIFYLMEFRE IFLTLLRKYD ERLQPRSFLR DLVESAHLFL RMLERFCKGR NNLVVQKKRV KRKKRSQKKP EMETSAEDLE QSWQIVSEEL RASGFQLPES LTEGAVPFDA ASDTPVNEQR TEALVRIQDC LMSRAGPEAL SLLRAARAVW PEGDTFGSVE VEPEEELELL KQILFTKLPR TVPLDSAVEE EDGDELVEEE ELESVAVSET EFNFLDFIKR FAHPNIVRPY VILLRSYSQN SPHTNHCVTR MLHRLAVDLK MEALLYQLSV FSLFNKILGD PAAAAYQELV KFAKYVLNRF FVFAATNNKA FVELLFWKNV GAVREMTEGY TKDGEGSKKK SKWTPEEEAE LQRLYEEHKD SGVPDVVETL LPLLSSSRTR REVVSHLVSM GLVDSVKDLK KEKKGTRIVL WTEEQEQELQ GLFEDFQDSD DVLGNILKRI TAKRSRARIV DKILSMGLVS DRKELYKKRQ RGAHGKSTGM TEEQFFDMTG EMQEKDIEDE EDDDEDDDDK SDQDEDEQHY EKQQTVRSAK KHQKSTSRDI SSEKIHSLRK MVQALQLEGL SGPVLWLQNS LNRTADDREE DGVSHPVALV PLTEENEDAM ENRSFQKLLR AVGIRAPSEG QETFWRISSS LSVNQLRTLA ASLEPLEETG AEGDSEEKDS RSVEDDENEN DNQEMRAQAL RALLLSRQRK HTSAKPKDSP SQEDISDSVE SSEQKISKKR SRVLDDDEDK DDEDQKDSPS QEDISDSVES SEQKISKKRS RVLDDDDEDD DDQKDVDPSS RSSERDSPAA PAKRRYTRVL SDEEEEDN // ID E7LZ74_YEASV Unreviewed; 1163 AA. AC E7LZ74; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 13-NOV-2013, entry version 4. DE SubName: Full=Tof1p; GN ORFNames=VIN13_3933; OS Saccharomyces cerevisiae (strain VIN 13) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=764099; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VIN 13; RX PubMed=21304888; DOI=10.1371/journal.pgen.1001287; RA Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H., RA Pretorius I.S., Egholm M., Chambers P.J.; RT "Whole-genome comparison reveals novel genetic elements that RT characterize the genome of industrial strains of Saccharomyces RT cerevisiae."; RL PLoS Genet. 7:E1001287-E1001287(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ADXC01000067; EGA77133.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1163 AA; 132895 MW; B514DF180459E22E CRC64; MAVAEYRILT DDLLPILIDW ENKCSLAAKL AKNNPDHEEF RNKAYYDKIA LNCLQLLVLM TWPLIVTEQS SSNQITLYGE LKKHQLVYKK TILSMESGKV LRAAIRLALD VIKIDRLSRT PRDNMVLKLV LNFFRNVIAI EPGEFTINTK KSMPKKGITS IDTLPPNVSM DDISLNTVIS SFHKNKVFGF LLTLTSSLSK EFDQDFINIP LLEIMFYFTK DVNQELLFPR QFETGTHSKV VNKNESSSAN NIVTSAGFEL SKLLQKEHQM RKNVIKHTSA RHSRFGGLLS IQTPDKTRLT VSGSQALVDE KIALQKLDDS KKWNKRIIKK HQSVAAEGLP NSLLNSQTGK AIFFTESNGK HFKEFINNFI DSGFNILLHS VTNYFTTEQD RMVTLEQVEY LLFFAWFVKY QLLRSKIDNS ADIKQVSEAL KEVTFILVSS LLRSAYDLKN WTVTHAGMIA FNELLNLVSR TKAAQEEDST DIEFIVSRLF SDERIQLLSN LPKIGSKYSL QFMKSCIELT HSVLKVLEQY SDDKTLVIEG KSRRQKKFNI SEXDITKLIE EENVDRDEAL DILTSSLRSI EVNFQKVQAN YMTEPVIETY INFLERFREL EDDSIKKVFS FFHRVFVQAK EQALLFRFDL IILLREMLSP DGLDRMSRSR KYVSQFSDYF LARLKKRLKK SPAWFVGLLF PPLHNSEVGF YQRYGEYNVL NNESMYAAPA SQFKPIPDEE ALPPSILLDM KYGILVSTLL DDGKTELLDQ LLKHITHTLD IFKSWLTVNV NAGKETVNPP NEYFTLTGVL NNDPIFKDKD YRALLLLIGY SIPRKINEPC FLPGTVEVSD LTVSCELVKK YLSTPFETPN GLPSSSYLLR VRSEKDSFSH NEQDGWEGDD DYDYNDPYIV PDDQILSKSD AAYFKDLDNN ASDKLKGTKF SKGIARSKKK DKRKRRKGEA KTNLPMFGDQ DDERPQTVRE RHGVFSKEFI SDSEDDEDLM NPIFFENETY MRWLLDKNNG QLTEDRYIQF AKFAAERMNN GGVVTGDYTS LFGGSIPSIE SIRATESSSF APDKSLISLA SHVASEMSIF DVNNNNNNQL SDDDVNSESR NSLGSSQPSN SQNMFQSEVY SRKESTKRSL EASAADESDE DEEAIRLFGK KSRVVLSQGD SDD // ID E9BXU8_CAPO3 Unreviewed; 1415 AA. AC E9BXU8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 16-OCT-2013, entry version 7. DE SubName: Full=Uncharacterized protein; GN ORFNames=CAOG_00958; OS Capsaspora owczarzaki (strain ATCC 30864). OC Eukaryota; Ichthyosporea; Capsaspora. OX NCBI_TaxID=595528; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=ATCC 30864; RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N., RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., RA Gargeya S., Alvarado L., Berlin A., Chapman S.B., Chen Z., RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., RA Heilman E., Heiman D., Howarth C., Mehta T., Neiman D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA White J., Yandava C., Haas B., Nusbaum C., Birren B.; RT "The Genome Sequence of Capsaspora owczarzaki ATCC 30864."; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; KE346360; EFW40433.1; -; Genomic_DNA. DR RefSeq; XP_004365829.1; XM_004365772.1. DR GeneID; 14902664; -. DR OMA; ARIECGR; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1415 AA; 158494 MW; EEF462BCC4E3E79D CRC64; MALALEDSLM VADLLSICSS LGDNIVEDGR EVYVIGDEAA ECIQDLLRCL RRDLSRSILR KLGEWCVLQE HLLPMLLTCP KDNPKLAFVT VKLLCTLTLP IKLAFEELKP DEDPNKDVLA KMEVTRYLQA AKRSFLREDV IYALIDLLSD ALTKDRFDRT ENDNNLMEIL FTLFRNLLHI PDPMQEPLQD ALIKMLQNAC FLDMVVSCIS TNNDTYASLN ELGIEAGQWN YFLLEIVYLL FRDVTATSLV NAQDEVDRGL DKNRVRDNLS REIVDSFKQE RREQLIRQGG NIGRARHSRF GGSFVLQQFD GSKQFFNRPI ASLNQFNVDE KKVDKKRASI GSSALVSEAS ATDALKALTD ASLDVVEDGS IDGFASGKLA DGQLRISAET RVVLLQFGQA FLESCFHPML VAVGKDLERG DVTPFYQEHQ AMYLWTIRFF LCLHREASQL AYKRLVKRYA VERKAYEAAS KLPTVLETRM AEPEAPPKFL LDMTAVGVVV TTTMMNRLIR ELHTNLDEFE NDRKERSAVN DMATAADGTL AGGKKRGNNA ALWTRRLQLT LLALQEFLQY VQVMSTSPDD LQRGVARSLH SNLFYEEETL DTLVKVLKEY DFRRQSKDYL RVVIETMHIL LRQLEHYSKE HSSMVVLSKR KTRRRKKTMS TMDTTLTPKK GRQDHNSAEA SEDETEEASA QHGEQSEETP KPPASATAEQ AGSNAAQAST TPVKKPVRAR RVIDDDDDDD DGDDNDEPDG AAASSTMASR APEQLPETTA PMETTEQQSA DAAAVVGFAF DAAPQEDEES LEQGQPQTTS TPPGENHEDV AARQPQADQA GQQTSKLSKG KRSRVVEDED EEDKDEDEEE ANAENRPSKL VDEEGLEEEL EDDDRDEAGI RHVEREFSFS KFESRFARPD VVTHLCRLMR DFKSNTPFTN HCIVKLCHRI AVHCDQVELF FHVSALTIFN TVLQDPDMQS SRGKANSSSS SSSKKDDSKS QPKLREDIQQ IKGFATFIAG KFFEALGDHP FLCLEALFWH SIRMPVHKNE AFTVRGRHID RSEYHEEHAV DIVDEDAAMD TSWSLTDELA QLRERERQAA ELARARAAEL RAPVRNPTST SSTNKASATV TPASKSSAAA TTPGKSKAAT PETSRKASAS TTKQQQQSKS KRAAGSDSDS DENEESGDDD DEDDDDDDDD MAAKQKKRRQ QSRRDRIQQR SQRRERQRAM QPDDDDDDDN DRRPAATALE VIEHRISAAP GRRRALVMSD DEENSDGEAP TPVATLAARA SNPATPARRR RRALSDDDED DENESDNRHQ QREEESPTKR QRLAGDPDES EEAAQPSNSF RLSAASLEAD DTAWNDNSRR IFPTESLSNP TTDSAFAAPE TYADVDQTPS FAAEPAAVSE PQTYVDNGQT PAFAY // ID E9D6X2_COCPS Unreviewed; 1171 AA. AC E9D6X2; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 13-NOV-2013, entry version 3. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=CPSG_05631; OS Coccidioides posadasii (strain RMSCC 757 / Silveira) (Valley fever OS fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Coccidioides. OX NCBI_TaxID=443226; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=RMSCC 757 / Silveira; RG The Broad Institute Genome Sequencing Center for Infectious Disease; RA Neafsey D., Orbach M., Henn M.R., Cole G.T., Galgiani J., RA Gardner M.J., Kirkland T.N., Taylor J.W., Young S.K., Zeng Q., RA Koehrsen M., Alvarado L., Berlin A., Borenstein D., Chapman S.B., RA Chen Z., Engels R., Freedman E., Gellesch M., Goldberg J., Griggs A., RA Gujja S., Heilman E., Heiman D., Howarth C., Jen D., Larson L., RA Mehta T., Neiman D., Park D., Pearson M., Richards J., Roberts A., RA Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., Walk T., RA White J., Yandava C., Haas B., Nusbaum C., Birren B.; RT "The genome sequence of Coccidioides posadasii strain Silveira."; RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL636493; EFW17994.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1171 AA; 133635 MW; B14EE97B38CAEE56 CRC64; MEIEPPQAVE VVDPEVRSYV YSLVTALGGT AGDETGQYVL GDDALGCLRD LKKWLRFYDE KLNRMDVARC LAECKLVNGD LVPIISLYGD AEQSDKHKAR IMLACLELLV PLTWPVEVHG QMTFNHHRHT PYLQYSQVEY KRGILGFAPS PILRALIRVG LPSMAIPRSE RSTRDEGIIR LMLYFFRNIA VITSPPNLPI DSDDDKATRS ATINAFQQQD VFALLLTMCS NMGNDFTFQD VIILEILFNL VKGVDVDQLF KLNERAGTIK TDDLQDILQK EDELNREHSK NAPTRHGRFG TMIWFKRDDE KLSTVSGQDV LKGDRATFLK MDKTKKWNKP KFKREVVDPS SNNFNLKVRL TSSATKHLRT FVEEFLDSGF NPLFTHLRKA IEREADRVTE STSRQFWYAV SWFLHAERAR RGHQKETRQR SKGTSREIEP DSFSLVASVL NQETFVGLNR FMQHSIDFKD WQDLTAGMKC LTQILLTVQE MAISPLEEDQ EIAENIQSRI FYEETTHDRV LSILRNHRDQ GFWYLDACTE LAHVFLRMLE QYSKQNVDMQ VRSRRRARRK QAQAAVPNQN ETEAGGEHDS ETEDIAEAHR TVTERSFDFK RFSVRFCTQK SVDTFVALTK YYRELDSEQL KRAHRFFYRV AFKQDMSVLL FRVDIISLLF KMIKGPEGLD PSKPPFKDWE ELIRQIFKKL VRKLGERPEL VVELLFSKIN ATVFYLEYGH EKQTMSESRP ATELELKPGS ASTLDEKTRI VVSALIQEGK KPLVKWLSQV LGSAASERLS WEMEAEAMAT SSPEEQSDGS KAPSIAVLPE DDGCRTAMFR NARLRLLMRL AGLERLDEDV LGASWMIPSS VPSSNLKEYH ELIEKHCESP AEDIDGVDPR DLMRRKRTAA DTNSSRHEFT ENVNFGSDSE GEDDGVLFPP NLPERSKALK TLKQRRRRRR RSDDAEESGP DEAVLEARRT AREKNALERQ RKIKSDLYVH ASDDESDEEA DIEFFAKEEM RRQAQARRVA EALETGMPEN NTTKKKSKAS AGRKRKVKPV LELDDDDSEA SPPKRRRSDE VIESDSDGEL MVGIGSTSPR RSQTPPTSAD NIFGSEKSPS PMFPWSVGVD QMIAKLQGKE EASADNGESN EDEGEDVLSG TGRTRRRRTM GGFVIGSDSD S // ID E9E7T8_METAQ Unreviewed; 1135 AA. AC E9E7T8; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 09-JUL-2014, entry version 6. DE SubName: Full=DNA repair protein (Tof1); GN ORFNames=MAC_05936; OS Metarhizium acridum (strain CQMa 102). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae; OC mitosporic Clavicipitaceae; Metarhizium. OX NCBI_TaxID=655827; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CQMa 102; RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264; RA Gao Q., Jin K., Ying S.-H., Zhang Y., Xiao G., Shang Y., Duan Z., RA Hu X., Xie X.-Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., RA Fang W., Wang S., Zhong Y., Ma L.-J., St Leger R.J., Zhao G.-P., RA Pei Y., Feng M.-G., Xia Y., Wang C.; RT "Genome sequencing and comparative transcriptomics of the model RT entomopathogenic fungi Metarhizium anisopliae and M. acridum."; RL PLoS Genet. 7:E1001264-E1001264(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL698517; EFY88072.1; -; Genomic_DNA. DR RefSeq; XP_007812276.1; XM_007814085.1. DR GeneID; 19250247; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1135 AA; 130459 MW; 4D4217DED37F6D08 CRC64; MEPLESAADI VHPEVRAHIG SLVSALGGTS AEDDGNYQLG DDALEVLRDL KRWIRFYDEK TNRMDVARCI YEANLIEGDL LPILRTWPEN AMDNKFRSRI ALACFELMVP LTWPIDWDKE RMTVNHHRHL PVLELAQVQY KRAIINFDGA RILHAAVRAA LPAMALPIGD RTARDQGIIK LVLFFLRNMA SITPPPNGKY KGDESQVSRS AIIDAFSYQD IFHVLLMLSS NMGEDFRTED TTVMEIIYHL VKRVDSEKLF MNEQQLNKAK ATELSALMNK ESAMLQSHNR KGATRHNRFG TMIWVKRDGG KMSSISGQDA LADSSIRNQK MDEIKKFKPP RRGRKDNQNE RDLGPPVKLN ARANDQLRKF VNEFLDSGFN PLFQHIRKTI DREAPHLLQY HRRQFFYLVA WFLEAERVRR KAKKPNSQES ADISSFQLVA GVLNQEMFIT LSRALQESYD MKDWTELTAV MRCFTQILLT VQEMAESANE DDQQIAENVL SRLFYEESAH DAIANIIRTY KDQGFDYLDA STELVHHFLR ILESYSKQNV DMQVRSRKRT RRKKKQAAKE GGDEEEAVLD DSADDEDAAE RTSKERKFDF HKFSARFTPQ GVVDTFIRFT KYYRDLTDTQ LKRAHRYFYR LAFKQDMSVM LFRVDIIHLL YNMIKGPNAL EKSSSMFKDW EELVKQILRK CTKKIQERPE LIIEMLFSKL QSTAFFLEYG HERQTTSKSQ PKPAAELEFK HTEERDQQVA IAVGALLDKN GTEHISWVRQ VLSDAESERR AWSAAADAKR DAEALFQDDP VITDTEPKTP PVFSVKPDGT ERRTAMFKNA HLRLLMKLSG MKLMGPASEE TPESIWIIPE TISADQLKDT IHFINQAEFS PPTFEDGFLA EHQLKRKAAP KKKAAFDDDE DADDDGFLDD EMLFPAGGPT ARKVVDEKKK PKKNRRRRTA SKRGELDDSV VEEKARKRRE KELEKARKIK SALYVRDGDD EFDSDEDEAF FAREREIAAR AKKAAETARE PILPPKKRKS TAMSDISDEE EEDDLSFARR VLSSQEGRES DTDDTPVDLS DGEARKRRKV GVEDHDGDGD ANMDVDIISK MTEMQDDDGE ETTQVVVTRR PRVRGGFVMD SDDDE // ID E9F6F9_METAR Unreviewed; 1141 AA. AC E9F6F9; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 09-JUL-2014, entry version 9. DE SubName: Full=Drug resistance protein MdrA; GN ORFNames=MAA_07858; OS Metarhizium anisopliae (strain ARSEF 23 / ATCC MYA-3075). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Clavicipitaceae; OC mitosporic Clavicipitaceae; Metarhizium. OX NCBI_TaxID=655844; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ARSEF 23 / ATCC MYA-3075; RX PubMed=21253567; DOI=10.1371/journal.pgen.1001264; RA Gao Q., Jin K., Ying S.-H., Zhang Y., Xiao G., Shang Y., Duan Z., RA Hu X., Xie X.-Q., Zhou G., Peng G., Luo Z., Huang W., Wang B., RA Fang W., Wang S., Zhong Y., Ma L.-J., St Leger R.J., Zhao G.-P., RA Pei Y., Feng M.-G., Xia Y., Wang C.; RT "Genome sequencing and comparative transcriptomics of the model RT entomopathogenic fungi Metarhizium anisopliae and M. acridum."; RL PLoS Genet. 7:E1001264-E1001264(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL698728; EFY96575.1; -; Genomic_DNA. DR RefSeq; XP_007824047.1; XM_007825856.1. DR GeneID; 19262144; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1141 AA; 131030 MW; D269D78A6657C262 CRC64; MEPLESAADV VHPEVRAHIS SLVSALGGTS AEDDGNYQLG DDALEVLRDL KRWIRFYDEK TNRMDVARCI YEANLIEGDL LPILRTWPEN AMDNKFRSRI ALACFELMVP LTWPIDWDKE RMTVNHHRHL PVLELAQVQY KRAIINFDGA RILHAAVRAA LPAMALPIGD RTARDQGVIK LVLFFLRNMA SITPPPNGKY KGDESQVSRS AIIDAFSYQD IFHVLLMLSS NMGEDFRTED TTVMDIIYHL VKRVDSEKLF MNEQQLNTAK ATELSALMSK ESAMLQSHNR KGATRHNRFG TMIWVKRDDG KMSSLSGQDA LADAAVRNQK MDEIKKFKPP RRARKDNQNE RDLGPPVKLN ARANDQLRKF VDEFLDSGFN PLFQHIRKTI DREAPHLLQH HRRQFFYLVA WFLEAERVRR KVKKPNRKES ADISSFQLVA GVLNQEMFIT LSRALQESYD MKDWTELTAV MRCFTQILLT VQEMAESANE DDEQIAENVL SRLFYEESAH DAIANIIKTY KDQGFDYLDA STELVHNFLR ILEAYSKQNV DMQVRSRKRT RRKKKQAAKE GGDEEEAVLD DSADDEEAAE RTSKERKFDF HKYSTRFAPQ GVIDTFIRFT KYYRDLTDTQ LKRAHRYFYR LAFKQDMSVM LFRVDIIHLL YNMIKGPNAL EKSSSMFKDW EELVKQILRK CTKKIQERPE LIIEMLFSKL QGTAFYLEYG HERQTTSKSQ RKPAAELEFK HTEERDEQVA IAVGALLDKN GSEHISWVRQ VLSDAESERR AWTAAADAKR DAEAMFGDDP AITDTEPKTP PVFSVKPDGT ERRTAIFKNA HLRLLMKLSG MQLMGPASEE TPESLWIIPG TISADQLKDT IHFINQAEFS PPTFEDGFLA EHKLKRKAAP KKKAAFDDEE DADDDGFLDD ETLFPAGGPT ARKLADEKKK PKKTRRRRKA NNTVELDDSV VEEKVRKRRE KELEKARKIK SALYVRDGDD EFDSDEDEAF FAREREIAAR AKKAAESARE PTLLPKKRKS TAVSDVSDED EEEEEEEQGD LSLARRILSS QEGGESDTDD TPVDLSDGEA RKRRRVSVEE RDGDNDADMD VDIITKMAEM QDDDGEETTQ VVVTRRPRVR GGFIMDSDDD E // ID E9FZ81_DAPPU Unreviewed; 1019 AA. AC E9FZ81; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_235857; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732528; EFX87311.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX87311; EFX87311; DAPPUDRAFT_235857. DR PhylomeDB; E9FZ81; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1019 AA; 116051 MW; 22CD4DE3A2F0BB45 CRC64; MDHWIKLSGE VPCLSLIPLG SFHNNKYCTD PECLNNLKEI NAKLSCEEPN TRPLRRAIGF FNVLNKDLIP ILLSSKDQPT IFRTTIKLLA ELTTPTECLI CIDASSNRSS TSQRIVIHEL SQLLYSIKEA FLEQPNATKV VIDHLHELLE KKTTLSREDC ECVQHSLLLV RNILHVPQRP RNTVVDVESA TSSAARQPRD AQTPHQVPAQ SNGSSCTTAD CNSQENQRLL WNLFAQRLDR LLINLLTSPQ KGDWIVTITQ LVALFYKDRH FEDMKKLMEA HPPTFESSDE HSDAINNTPP IVNADAHVTA YSPSKNFQFL SLTSSSIPSG EQYGPVANYG SQVETTTAMT TATIVSPGVT TPVTGKSGSN KRRMVSPETT HRSFSSASSQ CSHHSGCDIF VQRGNTSRHC SRHSTSSGFH SNESGIQYDN HRLKDSESRK KKSLKRRCHG NSNKFWEKNN VDVPSLLTID TMSDPCVSVF LLWSMKEIPE RFPRKKLRLI NRTADNYAKV NDNNYTPTEE DISHLLKDFI LDFLLDGYNT LVGQLHQKLL LQDNHPRLDK SHFLWLICYF LPFIPQLKLE VEHFPDVFSI DLLCYLTWEA VCQTEELEIY SFQPSVDVKP CVRRLHLVVK AIGEYLQALA KYSEADSSQI KGLTLKGHEE KRINQLCDFL PAIRDLRQVF LLQLRHFNPM IQSRRYLHDV ITTNHILLLT LEKAAKQSAH GAVGFEINQH LNQFCSRAIL NRYGNALEDF KTNGAFVNDC ILTILHHVGG DLGRTELLCQ PDILRPFTKI CDEDFTMCDD WTDLISYVIQ KYLRQVHVNS RFKTDWSQKS SNGLDDQEDL ICVKSENLTQ TEERFIRVLN EPTICENGDL IIRETRTEIE SLVRQLLNSG FRKQLVWIQS SLLTSCSARL GTYIGQEYRH PITCLSLQMN CPCPIVPWTE EEASALRSER FLCLLDRLSL LPSTPLALYP RIPCEWSAST IYSVALLFGP IVQQKIDFDT TRLSKIESPL SNLHRLVEF // ID E9FZ83_DAPPU Unreviewed; 98 AA. AC E9FZ83; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 7. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=DAPPUDRAFT_312499; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732528; EFX87310.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX87310; EFX87310; DAPPUDRAFT_312499. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 98 AA; 11029 MW; 894F4CE853E540D9 CRC64; MDHWIKLSGE VPCLSLIPLG SFPNKYCMDP ECLNNLKEIN AKLSCEEPNT RPLIAYAIGF FNVLNEDLIH ILHSSKDQPT ICPSIFPTTI TYSNVYSV // ID E9FZR9_DAPPU Unreviewed; 273 AA. AC E9FZR9; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 8. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=DAPPUDRAFT_307154; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732528; EFX87102.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX87102; EFX87102; DAPPUDRAFT_307154. DR PhylomeDB; E9FZR9; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 273 AA; 31123 MW; 3BF8845EE0A77A9A CRC64; MEQLMKLKFS GDIPCLSSIP LGTFHNNKYY IDDECLTHLE EINVMLKRED PNTRPLRRAI GFMDILNKDL IPILTSSKDQ PDIFYSTIKL LVELTTPVEC LMVSVDPSSR ISPSQHIAIH ELTQLLYGAK ESFLDGKTTQ VILNHLLHLS QKQLLSSDDC ELVNHSLLLI RNILHAPERP CQIAVGECQV SSTTSTQQQQ QNRILWNLYA QGLSHLLINL LGCSQATVKH YYFSIDIAGC LPCIFKQQST KAFYFLSFLF TKTDFNLLRI YFA // ID E9FZU1_DAPPU Unreviewed; 936 AA. AC E9FZU1; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_236054; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732528; EFX87203.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX87203; EFX87203; DAPPUDRAFT_236054. DR PhylomeDB; E9FZU1; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 936 AA; 106613 MW; E7F325970514BF6C CRC64; METKHDLGLE WHKMTDMRST AGVDFPDIQK SPQFRFSYSH DRRNPHGRWH PDYCCGSKME RRMTLSGHVP SLSLIPLGTC HNGKYYIDGE CLVHLEEINI KLINEDPITR PLRCALAFLD ILNKDLIPIL INSQDQSSIL NSTIKLLAEL TTPLECLGMV DLASQSNQSI TATQQVVIYK LTQLLCNAKE SFLDGGAMPA VFRHVRHTLE KEPLSSDDNL SVNHSLLLIR NILHAPERST QMADKGQDQQ DQLVRIVLAQ GLDRLLISLL ACAQKEQWLV AVVQLISLLY KDRPVEMILQ ILDEKCTHLD GDQQNQLGSK KSEKSLKKLS MKCKLGRPVE MKGNVVEYKP TDESTLILLK GFTINFIRQG YNTLVGQLHQ QMLKQHGDAH FQLLDKSHFL WLISYFLPIA SRLELSVEHL KDVLTIDLLC YLTWETVQQT EELEINAFQH SVDLKPCVRR LHLCVKAIRE YLKTLERFSR PLTSRNANAP DNLITRLGGY VPAIRDLRQL FLLQLRQFDP VVQSRRYLLD VIATNHILLL ALERSTAGQS SRGSFDISQH LTQFCSEMIV DRYGTALEDF QTNGPFVNDC ILTILHHVAG DLGRADLLCR PVILRPFSKI WAAEFNMCDD WNDLIELIIK KSMRSFQKSS IKETLRSNPN EPQEIKVSAS HLTETLPLKY SNEIPESADK NHLSCQVPDT NNQSLLIQLK DSGFQKQLEW IQSSLLSACA VRLGTYSGQE FRHPITCLSF QMNLSCPLVP WTEVEASALR SELFLNLLFR IGLIPPSPQP VLYPRIPREW SPDTLYSVAL LFGPVDQKRI DFDLTRVKKI ELDLPNLPIN VQNVQRPSLH SYIIHEGVSY REDSFLESKF PSAEINIPGQ NSIDGDFDQQ HSLRPLDSIS TTSSLEVHKM DSSDDEEMED LLFVTDEADY GCDVTR // ID E9G586_DAPPU Unreviewed; 943 AA. AC E9G586; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_313767; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732532; EFX85678.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX85678; EFX85678; DAPPUDRAFT_313767. DR OMA; THNDSES; -. DR PhylomeDB; E9G586; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 943 AA; 108335 MW; 5783D9C0CC0C50E8 CRC64; MDWLTLSGGA PSWILIPLGI FYENQYYTSD ECLTFLENLT NQLNCDDPKT HSRRRGLGFV DIINRDLKHI LICCNKDQPR IFRSTVKLLV GITSPIECLV FEDAPNQREK SPHIMYELNQ LLYKAKESFL DPRTTRSLID HIARILENQP VSTEDSESVN DSLLLIRNIL HVPERPLSSI SQNYSNECSR QNRVVWNLFV QGFDRLLINL LASSHKIDWV KTIAQLIALL YKDRSVENIQ KRLGALSSIV AESFDDDGDE SNTSFYNIDP CNTFQFLTNP TAGDVLRTPS DTSSPEENSE IVWSESPQER ESARWNAIAN QKPDKSRGHQ FISALNESSK SSIRRRVKDN RDVRKISSPR KKHKRKKLRK RSRSDPHTMK FHYTPTEEGI LQLLKIFTVD FMLNGYNTLV CQLHRKLLQQ DALPLDKSHF LWLITYFLRF TSQLEMDGEH LKDVITIDVL CYLTWEAVCE TEEFQLNSLR ADVDLKPSMQ RLHLCVTAIQ EYLQAVETHS RFGAENGPSQ VHEERISQIC GYLPAIRDLC LLFLLQLRHF DPSIQSRYYL CDIIKANHVL LLTLERATQQ PATGTNFDLR QHLQQFCKKT IIARYAMALE DFKTNGPLVN DCIFTMLHHV GCDLDRVDLL IEPVILRTFS KIWEDAFNIC DDWYDLTEYV AQKYFRKIQS KPHYETVSPR RSEFRSIESE HQRVSFDVPA EQADGEDDAV FLEMPRTDIE SLISQLIQTG FQKQLNWIQS SLLTACSARL GAYDGQEYRH LIACISLKMN LSCPIVPWTE VEASALRSEL FLLLLHHIGL IPPAPHAFLY PRIPFEWSAD TLYSFALFFG PVLQQEVDFD LTRVSKVELP IPNSPVFLPI PNFPIDQAGS PLHATEITQC GHNGYLDTTD QQNHLPIDNI RSTSSLEAFK TDSSEDEEMV DEVVIASALS TEG // ID E9GI54_DAPPU Unreviewed; 831 AA. AC E9GI54; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_103010; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732546; EFX80829.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX80829; EFX80829; DAPPUDRAFT_103010. DR PhylomeDB; E9GI54; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 831 AA; 94723 MW; A30B2FA3261B2E7D CRC64; MDWMLSSGGA PSMVLIPLGI RYNNQYYISI HCLSYLDDLI VQLKTDDKKT HSRRRGLGYV DIINTDLKPI LILSSKNDEP KIFRSAVRLL AEISTPIECL VFEETVNHAN GKSPNVIYEL TQLLYKCKEA FLDLSVIQAI MHNLEHLLEK QALSSEETIF ITFALVLFRN VLHAPERQPG AQQKLLCNLF SQKFDGFLLK LLACPQKGDW AAVITQIISV IFKDQPVENI QNRLRIKMET SGSENYDESN NSSDEVGQNS TPNEVSTFLD QFVVDFMLDG YNVVVGILHL QLLRDKNVPL DKPQFFWLIA YFLGFASILK LDLQSITNVL HIDILCYLTW EAVCEIGRLD KNTLQRSMDA NPRRIHRCVR AIREYLQACQ VYSRLDSTRV NISGPGSSHE YQRWSYLLRG YLPAMRELRQ LFVLLLRQFN PKFHCRRLLS DMITGNHLLL TTLKQANDFP ASVPRFDMMT EHLSQFCTKT ILARYGSALS DFRTNGPFLN DSIFTILLHV KNDLGKIDLL LHPVVLRPFV KIWEESFDIC DNWHTLIECV LQTFWKNHRS GNYSIGSYPW NTTTDGLADE ENLTLTKAKH PAGNNISSFN VLHTDTQSVV NQLKNSGFQK QLIWIQSSLL AACSARLGTY VGQEFRNPIA SLSLRTNMPC PIIPWTEEES FALNSDLFHS LIFQIGLIPP TSCDSVYPCI PREWSADTVY KVALVFGNVD QQNIDFDLAC VCKSQLNNRA VGPLFDISTD GFHQRICQMS AEKEQKQDEL LASLPEVSFN VWEWMEKSAE LGEIWAPEIE DAAISDMANG VNALGFFDEF SSREDEECAM E // ID E9GI55_DAPPU Unreviewed; 745 AA. AC E9GI55; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_243157; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732546; EFX80828.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX80828; EFX80828; DAPPUDRAFT_243157. DR PhylomeDB; E9GI55; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 745 AA; 84761 MW; 1EFC173409EBA459 CRC64; MDWMFSNGGA PSYVLIPLGT HYKRHYYTND QCSTNLEELV TQLQSDDPTN HSRRLGLGFV DIINKDLKPM LICCYKEEPA IFRSAVKLLV CITTPIRCLT FIETSSQRIH ASDIIFELRQ LLYRAKESFL DARSTRAIIA HIESLLELEH QPLTPENTVS VNLCLALLRN VLHIPERPSV RLPQMLLSSP QSGADNTLDD CQQNQIMCNL LAQGLGQLLL NLLACPQREE WVGTITQVIA VLFKGRSSET FRDRLSTDRT VMDSVTSESF EEDDDDDTCS VLSENISGFS YNTLVGTLHD QLLQHDLPID EAQFFWLITY FGGFAPLLKL DITHIKDVMN IEILSYLTWG VIHETEILDK NYFREVNLES SVRRLHRGVT AIRQFLQVME MYSKGVCWTS QQVESDDSQG CETYIRQLHS FLPVMKDLHQ AFLLLLRQYN PKVQDGHYLR DVIATNHFLL VTLERAAGVP AYGGSSVDLK EHLKQFCTPT IVARYGIALG DFRTNDIVFL HHVNGDLGRI DLLLNSIIVH PFVKICEEQF KVCETWHGMI QCVVQTFIRD QLSRGHQRTG ATSRLSESDQ VNPSSSAEPH HVASNPYPVF RQPRTNIETL LVQLKNSGFQ RQLDWIQYSL LTTCSAQLGT YDGQNFCNPI ACLSHRKKIS CPIVPWTENE ASALRSEIFV CLLQQLGLLP SIFRDPGFYP CIPYNWSPIT VFRKALVFSP IEQTMVDFDL SLVINRTDKS NPCPP // ID E9GIA4_DAPPU Unreviewed; 1197 AA. AC E9GIA4; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=DAPPUDRAFT_318263; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732546; EFX80642.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX80642; EFX80642; DAPPUDRAFT_318263. DR OMA; LHIPETH; -. DR PhylomeDB; E9GIA4; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1197 AA; 132720 MW; 37588C4A61960DAD CRC64; MDWLTLSGGV PSLSLIPLGI LHNNKYYISD DCLFHLEEIV VKLNCEDQTT RPLRCALGFM DILNKDLIPI LINSKDQPSV FCSTIKLLVG LTVPVECLVC VDTSNQSPTS QHIVHELTQL LYNAKEAFLD PRATRAVIDH LHRLLEKQPL SSDDSESVNH SLLLIRNILH APERPPNMTE VGDNEAATAS AQPGSNNSQT PYLGPHSHSH GFTADCSQQN RLLWNLFSQG LDRLLINLLA SSQKNEWVVT IVQLIALFYK DQHVENMQKL LGTWINPTTS ESSEDDDESN TSPPIGPCNS PQILTSSSDP TSDSSDSAQR KASALAPQDE NSEANPNESQ TETMTTIEKK AVVTNAASTT SPGATTQVAT GKSSRSKGHK FSTVSGAPGG DTASTSSTAP SQYSSQSDKS RRSSQHSVSS GFHSENSGNQ HPSHHAKDSD DHKEKSSKRR CHGNSQNSER RNETVIPTTI QTPVIIKEEI LSTSFSGTPT VTLQQTEDTN NKRSNKVTHK TGKVQPPEKE QRRKKLSKRS RTMGHIKMKA VQYTPTEEDI SQLLKEFTVD FLLNGYNALV GELHQQLLQQ DDLPLDKSHF LWLITYFLRF ASQLELDMEH FKDVFTIDLL CYLTWEAVRE TEEFEMNSLR PSIDLKPCLR RLHLGVTAIR EYLQALETYS RLGSSQNAAG NGSSQGYEER ICQLRGYLPA IRDLRQLFLL QLRHFNPIIQ SRRYLRDVIT ANHVLLLTLE RAAQQSTYGP SFDLRDHLHQ FCSKTILTRY GTALEDFKTN GPFVNDCILT VLHHIGADLG RADLLCEPVI LRSFSKIWEE EFNMCDDWDD LIEYVVQKFL RNFQTGGCYD VGSPQRSVSG SPDQEGGSPA TDTEAQQQFD AQASPAGDDD PFFDTPRTDI ESLRGQLMDS GFQKQLDWIQ SSLLVSCSAR LGTYNGQEFR NPIASLSRKM KVSCPIIPWT EVEASALRSD LFLFLLHRLG LLPPVPHAGL YPRIPPEWST DTIYSVALSF GPIDQQKVDF DLSLVNKVEL PIPSSLAEMP ADGSLPLTWQ PYLGPGPSTS LSAVPHHWLH WVEQSGSLFR SAEITSHGHN SSHSISNHSH RPLDSISTTS SLEVHKTDSS DDEEMEDAVL NACTGSGMGN MTEGEPVSSN ESVSMEEVRP DWAAMQMNTG GGGDSSSNEE MAAVGSEISL SRDGRDV // ID E9GIT3_DAPPU Unreviewed; 1097 AA. AC E9GIT3; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 10. DE SubName: Full=Putative TIMEOUT/TIM-2 protein; DE Flags: Fragment; GN ORFNames=DAPPUDRAFT_382; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732547; EFX80319.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX80319; EFX80319; DAPPUDRAFT_382. DR OMA; RKGTQIV; -. DR PhylomeDB; E9GIT3; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 FT NON_TER 1097 1097 SQ SEQUENCE 1097 AA; 126831 MW; D0EAD79FCF9E32FF CRC64; FMKAELTAAV TSLGYTEGNK YFKDQYCLEA LKDLIRYLRR DDDTIGIRRE LGQMKLVQTN LIPILCEYHS DEALFDVALR LLVNLTNPTL LLFNEEMPTD KVERNYYLQH VGHLQSYKPV LASDKFWVVL TDKLKLLLVK EPEDRMEDDK LLTERILILI RNILDIPITP EDEKRTDDDA SVHDQVLWSM HLSGMEDVII YLASNENERH FCMHVMEIIS LMLREQNPAS LAQTAAQRSV AEKQKDTEEL VAMVQKESSE REARYKKMTA SRSSIFRGTF CVKDVKSITD KDLIVHRTLT DGKPIDFHQN KTGKRKAKNR MPLPSCNVTR KSTLSIRLML KEFCLQMLNG AYNSLMHIVK DCLVRLKTQD HDETYYLWAV KFFMEFNRNC GKFRVELVSE TMSIGLFHYI QNQVQTYSES ITVDKKKAAL WSRRLNVALC AYQELLMTLN AMDKYGSESI RNSSRVLKSN VFYVPEYREM CLVLLLNYKE NQHSLTYLKD LVETNHIFLK LFEQFAKGNR HLVVQNKSKV PQKRKKSKPK KKKSEEEETP PPIFDEIAVE ISSALQEKPS LTDDVVPFDA ASDLPMDDQR VIAMGKIVKL LKESKSHLAV ALLRACREVW PEGEVFGAPE VGPEDELLLL RELYHTELPI DVAGEEPNAE SEEEDADNKE TEEEEEEMST VRRSEKELQF EEFIRRFAHK NVVKSYCHLL RSYSTNTTLT NHCVIKILHR IAFDCKMPAM IFQLSIFKTF QKIMDDPRAK TETTELYKFA IYIMRKFAET AQVNPKIFVE LLFWKTAREA AEIEVGYGNV QDPCTRFGWS EEEEDELQRL HQEFRDVQEG GDVVDRIMAN LINQTRSRRV IIKKMKEMGL IMDAKSLAKT KRSSKIRPSK EWTEHEVEEL RRIFPEVRES SDPLGMLIDR LPVRRAKNRV REKILELGLV EDVKELRKKR PGKSAGSKES NRDESDSEDG RAEPREGPAG LGDSESDESE ESDEGESDNE PVSKTKELKT QHRPKQYGRK EGLAWLVECL SETLEDREDG EGDEEAIPIV PLTDISNDAM EDHTFLKFIA KLGLAPPASE QEQFWRIPST LTSADLR // ID E9H6A2_DAPPU Unreviewed; 665 AA. AC E9H6A2; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_308128; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732597; EFX72619.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX72619; EFX72619; DAPPUDRAFT_308128. DR PhylomeDB; E9H6A2; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 665 AA; 76829 MW; F749DE04CED8E320 CRC64; MDRITLQPVF NDLQRLLENE SLSKEECRYI SDSLIHFRNN LCISEEFANE VSGESIVTAV SNIIVRPNSF VGNFTYHRSD IGSHLPKNCI LWNLFTLGID RLLINLLAHA EKTKWITTIA ELIALFYKER NDQNGVLNFL GIGVTASGDS DRPILSRSLE NSANAHLKPT NRRRMSDDVT EFFQPEPTEK EMSKLLTQFT LNFLLRGYNI LVSQLHEQLL LQKENNVNQN DKSDFVWFIS YFLPFVSQLK MNLNLFKDIF TIDILCYLTW ESVRQTEEFE MNSLRLSPPV DLKSNQRRLH RSVKAILEYL RILEEHTRPS NNFEKHGLRR ELQERVCKQL CSYLPAARDI RQLFLLQLLQ FNPDIQSRRY LCDVVTANHL LLLILERVPH EEPGGANFNL HQHLNQFCTK TIMARYGTAL EGFRTNGPFV NDCIFTMLHH VGCDLREIAL VCQPNIMRHF ASIWQEAFQI ADDWHDLISY AVHIFNLSRG KIGNISPDRE TSEFLNPDDW RSMEFESLTS QTFNNDDDEL ENLRTDFESL LILLKGDGFQ KQLDWIQSSL LTACAARLGI YSDHEFRHPI TCLSLKLNTP CPIVPWTEAE ASALSSKPFR FFLRQLGLFP SLPHAGTYPR IPLEWSPDTL YNVALSLGSV VHQQVDFDLS CVGKL // ID E9HAR2_DAPPU Unreviewed; 896 AA. AC E9HAR2; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 11-JUN-2014, entry version 9. DE SubName: Full=Putative TIMELESS/TIM-1 protein; GN ORFNames=DAPPUDRAFT_309208; OS Daphnia pulex (Water flea). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Branchiopoda; OC Diplostraca; Cladocera; Anomopoda; Daphniidae; Daphnia. OX NCBI_TaxID=6669; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21292972; DOI=10.1126/science.1197761; RA Colbourne J.K., Pfrender M.E., Gilbert D., Thomas W.K., Tucker A., RA Oakley T.H., Tokishita S., Aerts A., Arnold G.J., Basu M.K., RA Bauer D.J., Caceres C.E., Carmel L., Casola C., Choi J.H., RA Detter J.C., Dong Q., Dusheyko S., Eads B.D., Frohlich T., RA Geiler-Samerotte K.A., Gerlach D., Hatcher P., Jogdeo S., RA Krijgsveld J., Kriventseva E.V., Kultz D., Laforsch C., Lindquist E., RA Lopez J., Manak J.R., Muller J., Pangilinan J., Patwardhan R.P., RA Pitluck S., Pritham E.J., Rechtsteiner A., Rho M., Rogozin I.B., RA Sakarya O., Salamov A., Schaack S., Shapiro H., Shiga Y., RA Skalitzky C., Smith Z., Souvorov A., Sung W., Tang Z., Tsuchiya D., RA Tu H., Vos H., Wang M., Wolf Y.I., Yamagata H., Yamada T., Ye Y., RA Shaw J.R., Andrews J., Crease T.J., Tang H., Lucas S.M., RA Robertson H.M., Bork P., Koonin E.V., Zdobnov E.M., Grigoriev I.V., RA Lynch M., Boore J.L.; RT "The ecoresponsive genome of Daphnia pulex."; RL Science 331:555-561(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL732613; EFX71071.1; -; Genomic_DNA. DR EnsemblMetazoa; EFX71071; EFX71071; DAPPUDRAFT_309208. DR PhylomeDB; E9HAR2; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 896 AA; 101887 MW; BCE3489423B162CB CRC64; MTLERDIESS SSSWLHRTNY AAIILHARSQ SPSISKAYSI YRQSCVNFEM DEWVKLSGNV PSLSLVSLGT FHNSKYHASN ECLDCLNEIN AKLNDKGPHT YPLRRALIFM DIFKKDLIPI LIHTVGSDDF TRWMFSRRGK QPNATTPMSK LFVHELNNFL YVAKETFVLN PLATRSIFEH LNCLLANVPQ QPISKDDCES DEWIVTIAQL ITLIFKDHTP EKIQKLVSSE QTHSEIPLPS SSDDDTDSGN CSQTSSCNSA TETANKMKTS GKFYWTRKPT TTEMFRSKKK HFVATMKTAD KEQIPDSQSG YQRRKKILTS RRSRAIARHI QTKSKIPNYT PSEDEISQLL KEFTSSLPMF DKSYFLWLIS YFLPIALHLE LDIFKHLKDV VCVDIISYLT WESASESEEF EINSLNSADL QPVLRRMQLG VKAIRECLLA LEARSSYVGK ADGSYCQEQM NLFKFRASLA NANDLRQLPL LQLRQFDPAI QNKKYLGDVI TTNHVLLKTL EQAAGQPSAY NCNLDFGGHF EQFYSKVILN RYGSALDDFR TNDPFVNDCV FTLLRHVGVY RGRADLLCDP AILRPLGKIW EEGFNICQEW NDLIELIVNK FMRHYEANGC QAMKSPDRVV TASEKAETSQ VKQGNSNPTK IESLRDQLVK SGFQKQLDWI QSCLLTSCSA RLGTYAGQEF RHAIICLSMK MNVPCPIVPW TELEDSALRS QQFLHFLQRV GLFPDSYQPS LYPRIPRHWS ADVLYSVALI FGPVHQQRID FDLSRVRPIK LNIPDSAVDL QSNGQMMFNT PASNQSDEPV TGDNSSMSRA DSLEVEKNDS SEDEEMECSD SSSSRKLTIS PRNSSELRVP LDWSVHPDMG RQLSADGDVT FQMGSIGYEI SRIFLT // ID E9JCZ4_SOLIN Unreviewed; 241 AA. AC E9JCZ4; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 05-APR-2011, sequence version 1. DT 19-MAR-2014, entry version 6. DE SubName: Full=Putative uncharacterized protein; DE Flags: Fragment; GN ORFNames=SINV_15526; OS Solenopsis invicta (Red imported fire ant) (Solenopsis wagneri). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Vespoidea; Formicidae; Myrmicinae; Solenopsis. OX NCBI_TaxID=13686; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21282665; DOI=10.1073/pnas.1009690108; RA Wurm Y., Wang J., Riba-Grognuz O., Corona M., Nygaard S., Hunt B.G., RA Ingram K.K., Falquet L., Nipitwattanaphon M., Gotzek D., RA Dijkstra M.B., Oettler J., Comtesse F., Shih C.J., Wu W.J., Yang C.C., RA Thomas J., Beaudoing E., Pradervand S., Flegel V., Cook E.D., RA Fabbretti R., Stockinger H., Long L., Farmerie W.G., Oakey J., RA Boomsma J.J., Pamilo P., Yi S.V., Heinze J., Goodisman M.A., RA Farinelli L., Harshman K., Hulo N., Cerutti L., Xenarios I., RA Shoemaker D., Keller L.; RT "The genome of the fire ant Solenopsis invicta."; RL Proc. Natl. Acad. Sci. U.S.A. 108:5679-5684(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL771866; EFZ09326.1; -; Genomic_DNA. DR EnsemblMetazoa; SINV14842-RA; SINV14842-PA; SINV14842. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. FT NON_TER 1 1 FT NON_TER 241 241 SQ SEQUENCE 241 AA; 27748 MW; 4BBE1ECEAC8ADAD6 CRC64; VIKDLIRYLK RDDDTHTIRR FLGQTKVLQT DLVKILMYHV ENTELWDVLL RLLINLTSSA FVIYNEQIPT EKTTYSLYQQ IVSYLQEYKA ALADENVWSV VAGRLGNLLN IDSSERGEEN ELTIERILAF IRNVLQVPPN DNDKRADNDA TVHDEVLFAF HASGIVDILL FIVSNNQEQQ YHMQILEIIS LMLREQNASV LATSGLQRST AERENDEATL VALRQKELRE KINKVKKYAG S // ID E9PTS7_RAT Unreviewed; 1207 AA. AC E9PTS7; DT 05-APR-2011, integrated into UniProtKB/TrEMBL. DT 03-APR-2013, sequence version 2. DT 14-MAY-2014, entry version 21. DE SubName: Full=Protein timeless homolog; GN Name=Timeless; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Brown Norway; RX PubMed=15057822; DOI=10.1038/nature02426; RG Rat Genome Sequencing Project Consortium; RA Gibbs R.A., Weinstock G.M., Metzker M.L., Muzny D.M., Sodergren E.J., RA Scherer S., Scott G., Steffen D., Worley K.C., Burch P.E., Okwuonu G., RA Hines S., Lewis L., Deramo C., Delgado O., Dugan-Rocha S., Miner G., RA Morgan M., Hawes A., Gill R., Holt R.A., Adams M.D., Amanatides P.G., RA Baden-Tillson H., Barnstead M., Chin S., Evans C.A., Ferriera S., RA Fosler C., Glodek A., Gu Z., Jennings D., Kraft C.L., Nguyen T., RA Pfannkoch C.M., Sitter C., Sutton G.G., Venter J.C., Woodage T., RA Smith D., Lee H.-M., Gustafson E., Cahill P., Kana A., RA Doucette-Stamm L., Weinstock K., Fechtel K., Weiss R.B., Dunn D.M., RA Green E.D., Blakesley R.W., Bouffard G.G., De Jong P.J., Osoegawa K., RA Zhu B., Marra M., Schein J., Bosdet I., Fjell C., Jones S., RA Krzywinski M., Mathewson C., Siddiqui A., Wye N., McPherson J., RA Zhao S., Fraser C.M., Shetty J., Shatsman S., Geer K., Chen Y., RA Abramzon S., Nierman W.C., Havlak P.H., Chen R., Durbin K.J., Egan A., RA Ren Y., Song X.-Z., Li B., Liu Y., Qin X., Cawley S., Cooney A.J., RA D'Souza L.M., Martin K., Wu J.Q., Gonzalez-Garay M.L., Jackson A.R., RA Kalafus K.J., McLeod M.P., Milosavljevic A., Virk D., Volkov A., RA Wheeler D.A., Zhang Z., Bailey J.A., Eichler E.E., Tuzun E., RA Birney E., Mongin E., Ureta-Vidal A., Woodwark C., Zdobnov E., RA Bork P., Suyama M., Torrents D., Alexandersson M., Trask B.J., RA Young J.M., Huang H., Wang H., Xing H., Daniels S., Gietzen D., RA Schmidt J., Stevens K., Vitt U., Wingrove J., Camara F., Mar Alba M., RA Abril J.F., Guigo R., Smit A., Dubchak I., Rubin E.M., Couronne O., RA Poliakov A., Huebner N., Ganten D., Goesele C., Hummel O., RA Kreitler T., Lee Y.-A., Monti J., Schulz H., Zimdahl H., RA Himmelbauer H., Lehrach H., Jacob H.J., Bromberg S., RA Gullings-Handley J., Jensen-Seaman M.I., Kwitek A.E., Lazar J., RA Pasko D., Tonellato P.J., Twigger S., Ponting C.P., Duarte J.M., RA Rice S., Goodstadt L., Beatson S.A., Emes R.D., Winter E.E., RA Webber C., Brandt P., Nyakatura G., Adetobi M., Chiaromonte F., RA Elnitski L., Eswara P., Hardison R.C., Hou M., Kolbe D., Makova K., RA Miller W., Nekrutenko A., Riemer C., Schwartz S., Taylor J., Yang S., RA Zhang Y., Lindpaintner K., Andrews T.D., Caccamo M., Clamp M., RA Clarke L., Curwen V., Durbin R.M., Eyras E., Searle S.M., Cooper G.M., RA Batzoglou S., Brudno M., Sidow A., Stone E.A., Payseur B.A., RA Bourque G., Lopez-Otin C., Puente X.S., Chakrabarti K., Chatterji S., RA Dewey C., Pachter L., Bray N., Yap V.B., Caspi A., Tesler G., RA Pevzner P.A., Haussler D., Roskin K.M., Baertsch R., Clawson H., RA Furey T.S., Hinrichs A.S., Karolchik D., Kent W.J., Rosenbloom K.R., RA Trumbower H., Weirauch M., Cooper D.N., Stenson P.D., Ma B., Brent M., RA Arumugam M., Shteynberg D., Copley R.R., Taylor M.S., Riethman H., RA Mudunuri U., Peterson J., Guyer M., Felsenfeld A., Old S., Mockrin S., RA Collins F.S.; RT "Genome sequence of the Brown Norway rat yields insights into RT mammalian evolution."; RL Nature 428:493-521(2004). RN [2] RP IDENTIFICATION. RC STRAIN=Brown Norway; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AABR06047168; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSRNOT00000047241; ENSRNOP00000043366; ENSRNOG00000031916. DR RGD; 620939; Timeless. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR NextBio; 35575154; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1207 AA; 138709 MW; E44B037C011E4ABD CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDPTVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKRID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQK PEQLAGVGQG RLAQERSTDL AELEVLRQRE VAEKRARALQ RGNRHSRFGG SYVVQGLKSI GERDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLREKA QQHDETYYMW AMAFFMAFNR AAAFRPGFVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDDA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLC DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKKKKKAQE QGVAFSRSPE ELQAMWSALA ERLLQCAQEP ELSVDSIIPF DAASEVPVEE QRVEAMVRIQ DCLVAGQAPQ ALALLRSARE VWPEGNVFGS PVISPGEEMQ LLKQILSATL PRQQEPVEGD AEEEDEEEEE EEEEELQVVQ VSEKEFKFLD YLKRFACSTI VRAYVLLLRS YRQNSAHTNH CIAKMLHRLA HDLGMEALLF QLSLFCLFNQ LLSDPAAAAY KELVTFAKYI LGKFFALAAV NQKAFVELLF WKNTSVVREM TQGYGSLDSG SCSHRAPVWS SEEEAQLQEL YLAHKDVEGQ DVVETILAHL KAVPRTRKQV IHHLVRMGLA DSVKDFQRKG TQIVLWTEDQ ELELQRLFEE FQDSDDVLGH IMKNITAKRS RARVVDKLLA LGLVSERRQL HKKRRKKLAP SCMQNGEESQ RDAWQEDPEE EEEKEGLPES EGEENEEDLL AGQVQGSSSL SAENLRQSLC QDGLSAPLLW LQSSLIRAAD DREEDGCSQA IPLVPLTEEN EEAMENKQFQ HLLRKLGIRA PCSGQATETF WRIPAKLSST QLRRVAASLS EQENKEEREE EPEPNPGVPG EQSPSEEHQV RAPRALLSAR KRKAGLVFPK EEATGEEEWK SVPKKQQLLD SDEEDTDDER GGQAAVSGTL RIHKKKRFLV EDEDEDY // ID F0UIG0_AJEC8 Unreviewed; 1110 AA. AC F0UIG0; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 22-JAN-2014, entry version 6. DE SubName: Full=Topoisomerase 1-associated factor; GN ORFNames=HCEG_04780; OS Ajellomyces capsulatus (strain H88) (Darling's disease fungus) OS (Histoplasma capsulatum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=544711; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=H88; RA Champion M., Cuomo C., Ma L.-J., Henn M.R., Sil A., Goldman B., RA Young S.K., Kodira C.D., Zeng Q., Koehrsen M., Alvarado L., Berlin A., RA Borenstein D., Chen Z., Engels R., Freedman E., Gellesch M., RA Goldberg J., Griggs A., Gujja S., Heiman D., Hepburn T., Howarth C., RA Jen D., Larson L., Lewis B., Mehta T., Park D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA Walk T., White J., Yandava C., Klein B., McEwen J.G., Puccia R., RA Goldman G.H., Felipe M.S., Nino-Vega G., San-Blas G., Taylor J., RA Mendoza L., Galagan J., Nusbaum C., Birren B.; RT "Annotation of Ajellomyces capsulatus strain H88."; RL Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS990639; EGC45565.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1110 AA; 127533 MW; B05266E630032DC3 CRC64; MELESIQSGQ VVDPEVRAYV YNLVSALGGS GSSNTGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAETNLVNRD LIPILALLGD DIHDDKYKSR VSLACLELLV PLTWPLEIHS QMTVNHHRHI PYLQHSQVLY KRGILGNDTS AILRTIIRIA LPSMTTPRSD RSSRDEGILK LMLYLFRNIA IVTPSHLAAE GDEEEASKSA TINAFQQQDV FALLLAMCSN IGEDFIYQDV VILEILFHIV KGVDIKKLFM NDTQRNIAGT DDLEALLDKE SHLKREYAKT APTRHGRFGT MIWVKRDDEK VSTVSGQDVL KDDWTTMLKM DKSKKWDRPK HRKGDIDMSV NNFNVPSPLT PLATKHLRTF VEEFLDSGFN PLFSHIRKAI EREADRVTES TPRHFFYVVA WFLEAERVRR TRQQELRQQN AHPSRDFEPD GFQLVASVLN QETFIALTRH MQSCLDFKDW QDLNASMRCF TQILLTVQQM LHSDIAEDQD IAENILSRIF YEETTHDRIL AILRVYESQG FWYLDACTEL AHVFFRLLEQ YSKQNEYMQI RSRRRARRKQ CKKAAPNPEN GEAQDGDESE AEDLTMEDAT KTIVERSFNF QRFAAKFCTQ NSVNTFLALT AYYRELNEEQ LKRAHRFFYR VAFKQELSVL LFRVDIISLF YKMIKGPKGL DSTKPIYVEW EELTRRIIRK LVKKLEQRPE LITEMLFSKI NATVFYLEYG HERQTVSQSK AAAELEVKPG AANTLDSKLG IVVAALLLEG KESLVQWLIK TIDTAVNERR SWELEAEARR SESGEERTAN TPPSIAVIPF DDACRTAMFK NGRLRLLMTS AGLERLGVED TLGSSWIIPS SLSAKTLEET KKSIEKHKEN PPTEFDGLEP RGLLRRKRDI DITLSHQRTS GEVDFGNDSE GEDDIDDILF PPNLRTRADT LDELKKKRLR RGKENGKDVD VLDEASLEAR RLARHANALE RQRKIKSSLY IHASDEESDE EADREFFARE EERRRNQAMR IKQALLLDAT GGDDLPDQNS SSKARKRKGT SDEDEVNKRR RNDHLLPDSD EEVDLTSIDG HQDNDEENGL MVTQDEPSSS SETTSMSFGW // ID F0WX56_9STRA Unreviewed; 865 AA. AC F0WX56; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 11-DEC-2013, entry version 5. DE SubName: Full=Putative uncharacterized protein AlNc14C342G10814; GN Name=AlNc14C342G10814; ORFNames=ALNC14_121900; OS Albugo laibachii Nc14. OC Eukaryota; Stramenopiles; Oomycetes; Albuginales; Albuginaceae; OC Albugo. OX NCBI_TaxID=890382; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=21750662; DOI=10.1371/journal.pbio.1001094; RA Kemen E., Gardiner A., Schultz-Larsen T., Kemen A.C., Balmuth A.L., RA Robert-Seilaniantz A., Bailey K., Holub E., Studholme D.J., RA Maclean D., Jones J.D.; RT "Gene gain and loss during evolution of obligate parasitism in the RT white rust pathogen of Arabidopsis thaliana."; RL PLoS Biol. 9:e1001094-e1001094(2011). RN [2] RP NUCLEOTIDE SEQUENCE. RA MacLean D.; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FR824387; CCA26046.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; SQ SEQUENCE 865 AA; 99633 MW; 9B16360B2FE6CB2F CRC64; MIGQYPSLLD WLKTFNAMSL IPNDENDTEI AVEYEDIDMD SEGEEDCFIS GENVYQLGNS MMNELLLICS NLGLLQTDSD QSSNRAAIIR GEDCEEWIHD LQRAIRRDHE KKKLISKQLG KWKIVQKKLL PLLLNHQHDW SLVFSILKIL VMLTMKPSSD SNDIPQQLHF IREYKHAILS QRVVPVLMAA LGDPLSRQGT NRTSEDYLNI ELILTLFRNL LATPNEDVRY VTSATEYFTH LQEDFIKVLH QEHLYEMILL IASNIESSEY RDWNLLILEI LDQTLACCCP HAIANHMKST TTQNSTHPKS SLLNEIKAQK KQIAGRHSNF GGVLKVQSVS GNAILMSNLK RKNAFTMASP SKPLRRRGKS AGQADLSDIF RPKTSADTTD KNTINVVYEL CESILTSAYY PLTNSLKNEF RRGSSKLVPA DRMQYFHFVW FLLTYQRERV HHLTTDTSEN TQKSANEKAA LATLDMFSFN FVLQSIENYE STKNHSGMCV AVKLLKEKMA YVSELLGSQD LRLVHLAQSI QHKLFYERDF LDRLPLLIRS WTSMHSIAYS TDVVILTHLV LKGLDAHGHI KVLGKKTSKI NKAIDSEEVQ QTITRKEADF DLHRYFRSIL NHDTIRMYAF VLGNYRENSV KVNHYIHSFF HRVSKFQIEG ELTTKPMLFH IRVLTVFNAV LQDKTINNDQ WYRSLVAFIQ SIVRDFFALA EKNHLLYVEA LLRQSYAVKS CISMQRIYEP IVPMAPRKSA VEVKRAEQRL SDEGEVEFKL SVTESGGEVV WSSLEDRYLS TIYKQFRDHP SRFELLSEEN LLCDRTPAEI EKRVEKLGLD TEKTTEVIHS PKRLRRAIDA SSDCEDESVF DTEQQ // ID F0XEA4_GROCL Unreviewed; 673 AA. AC F0XEA4; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 22-JAN-2014, entry version 5. DE SubName: Full=DNA repair protein; GN ORFNames=CMQ_1043; OS Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) OS (Graphiocladiella clavigera). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Ophiostomatales; Ophiostomataceae; OC Grosmannia. OX NCBI_TaxID=655863; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=kw1407 / UAMH 11150; RX PubMed=21262841; DOI=10.1073/pnas.1011289108; RA DiGuistini S., Wang Y., Liao N.Y., Taylor G., Tanguay P., Feau N., RA Henrissat B., Chan S.K., Hesse-Orce U., Alamouti S.M., Tsui C.K.M., RA Docking R.T., Levasseur A., Haridas S., Robertson G., Birol I., RA Holt R.A., Marra M.A., Hamelin R.C., Hirst M., Jones S.J.M., RA Bohlmann J., Breuil C.; RT "Genome and transcriptome analyses of the mountain pine beetle-fungal RT symbiont Grosmannia clavigera, a lodgepole pine pathogen."; RL Proc. Natl. Acad. Sci. U.S.A. 108:2504-2509(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL629765; EFX04115.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 673 AA; 76328 MW; 524F6AFAF2B6C12C CRC64; MEPTESPADV VHPEVRAHIT SLVSALGGTD EDGQYQLGDD ALDVLRDIKK WIRFYDQKLN RMDVARCLAD TNLVGGDLLR ILATWHENAT AQRFKARVAL ACYEVLTPLT WPLETDVETA TVNHYRHLPV LQLAQLAYKR AIINFDGAQI LHTAVRVALP AMAVPLADRS MRDQAIIRLV LFFLRNVAMI EPPAGVKYDG DESQVSRSAT IDAFSYQDIL LLLLTMASNM GDDFRTEDAT VMEIVFHLIK RVDVQKLFMD EAQLSSTKAE ELTALMHKEA AMLQSFRPHG PTRHSRFGTM VWVDRGEGRM SALSGQDALV SASARELKMD TSKKFRPPRR PRRRRDEKQE LMGLGPSVSL NARANGQLRH FVDELLDSGF NPLFLQARRS IEREAPHIQH HHRAQFLYLV AWFLEAERAR SKAAAQKRGR KDPTGDVSSF NLVAGALNQE MFIFLNRVLD QAQNDKDWAE LTVVMRCYTQ ILLTVQQMSE SRSEEDEEIA ENILSRLFYE EATHDAVANL VKNYKDQGYE YLDACTELAH TYLRILETYS KQNVDLQVRS RRRTRKKKAA KKAVKTTAAT DSAGNGDDNG EEAAEDEQQQ NDDEDDESGN DEALAQKTST ERKFDFSRFA NRFAVQGVID TFVKFTSNYN DLTEAQLKPE RTGTFTESRS SKR // ID F0ZV88_DICPU Unreviewed; 1403 AA. AC F0ZV88; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 06-MAR-2013, entry version 9. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=DICPUDRAFT_98969; OS Dictyostelium purpureum (Slime mold). OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium. OX NCBI_TaxID=5786; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=QSDP1; RX PubMed=21356102; DOI=10.1186/gb-2011-12-2-r20; RG US DOE Joint Genome Institute (JGI-PGF); RA Sucgang R., Kuo A., Tian X., Salerno W., Parikh A., Feasley C.L., RA Dalin E., Tu H., Huang E., Barry K., Lindquist E., Shapiro H., RA Bruce D., Schmutz J., Salamov A., Fey P., Gaudet P., Anjard C., RA Babu M.M., Basu S., Bushmanova Y., van der Wel H., Katoh-Kurasawa M., RA Dinh C., Coutinho P.M., Saito T., Elias M., Schaap P., Kay R.R., RA Henrissat B., Eichinger L., Rivero F., Putnam N.H., West C.M., RA Loomis W.F., Chisholm R.L., Shaulsky G., Strassmann J.E., RA Queller D.C., Kuspa A., Grigoriev I.V.; RT "Comparative genomics of the social amoebae Dictyostelium discoideum RT and Dictyostelium purpureum."; RL Genome Biol. 12:R20.1-R20.23(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL871210; EGC32123.1; -; Genomic_DNA. DR RefSeq; XP_003291332.1; XM_003291284.1. DR GeneID; 10507525; -. DR KEGG; dpp:DICPUDRAFT_98969; -. DR KO; K03155; -. DR OMA; GEDCLEA; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1403 AA; 165169 MW; C63BEC831A2EEFF0 CRC64; MDESELVALL SELGSWKRNK SNNDNDNNNN NNNNNNNNNI KQLNKNIKKN FQLNKEQEDL TIQNEYDSNS NRTFECGEDC LEAARILYRM LKEDDEIDRA VFHYLGKNNI VKNKLIPLLI TQASNTDLVI SILRIYVNLT YQLPINIESY EIPKQNLYML NFKESFLNRE LLKTFLRILN EPMTRLSLSS GSNQDYLIIE LILTLIKNVL QIQDPISSVS LEFEYRCHMH SKLIELLEES EILELFLILS ETIKKDKIFK SITNYSLLLL EIFTLLLKND TPNEIWSNES TTSTPSSAST STLNDELEKK ESLINLLKKE KKLSTKLITN SNTSRFIGAY SSFSNVDGKK IINKTLPDLA TQNAIRPTNL HSGVFNSSLL SSRVKAIGER KRTPSSLQVR SILKNWSEQF LDGSYDNLMS IIIQEFAKDD NQILDSEKLN FLLLTKFFTG FSLQLLRYVS KQQEEKKKNQ QMEKELEEGV DKRFEPQDDD EEADEIGVDK FTIDNIIGSL SSTLSISNFQ FIFGCCSTYQ TTKNNLSLEI CVSTLREMIS LLNYMSHSSV EEYIKISYEM QSSIYYDRDA YLKLIVTLMR NYQPSIFSKS MIIDLIDLAH TTITMVENFC KKNQSIVVKS KRQSKKAKRL NEADDQAIKE DDNDDDSTNK KDEEENEDNE DQEEEIENQV KSSMDFESFM AEFANYDIIR NIALVLGCYH TNSDILNYQI IEIYKRIAQD LDLEPMFYQI SLFYLFKNLL NDPLIISKDK NSKQLFQVIN QILTNYFKAV ETNQTLLIDI LIPKHKTDCF YINNNKHQPG LEDEIGGIPQ QNEEDEDSSL TISKETGRLK KMKSDDSDDG ENYFEDEDKM ILQNVISKLE DSLDRERLTS IVQKINSTKN GSTIIEWLQD HLLNAITKRN KEKNNPKYTL YQLEYNENQN YNTNRQLDIL FKIVLKFKLP ISKTDNYSIP EFKIYSPSYL TTIYETIKEA LLNQENEKIE KLKKKEILEK EKLNKLNKKE KRKLKRVKDD DDEEKEEIMN DDQEEVMNDD QEEVLNEDQE EVMDDDQEKE ITKVKKNKKD KKKSKKHKKE YVEEDQEENN EEVEEEQIVN AEEEQVEEEG DDQVEETKAE RKARRKIEKA EKRARKKEKR EKKERKRKEK MELEEQEMEE VEEVEEQEKE REEQEEQEIE EAEEVEEQEE EEQEIKKDKK KKKKKEKKNK LKDDKEDDED FEPLFPESDD DNIEKESSKK RKNISKKTKK EYREEEENQQ NQQEKVQDQQ QDEQKEDQTE KAQDQQQEKD QQEQPEKVQD QQEYQPKKVQ EQQDQQEKVQ DQQDNLPEKV QEQDQQEYQP EKFKIFIDFL KIICTSGQNG GNLLMTCGHK LILIINSNSN NINNNNNFSS NNNNFIITIK EIF // ID F1KRU9_ASCSU Unreviewed; 1302 AA. AC F1KRU9; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 03-OCT-2012, entry version 4. DE SubName: Full=Protein timeless; OS Ascaris suum (Pig roundworm) (Ascaris lumbricoides). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Ascaridida; OC Ascaridoidea; Ascarididae; Ascaris. OX NCBI_TaxID=6253; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=21685128; DOI=10.1101/gr.121426.111; RA Wang J., Czech B., Crunk A., Wallace A., Mitreva M., Hannon G.J., RA Davis R.E.; RT "Deep small RNA sequencing from the nematode Ascaris reveals RT conservation, functional diversification, and novel developmental RT profiles."; RL Genome Res. 21:1462-1477(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JI164839; ADY40603.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1302 AA; 150037 MW; F372F1934A605436 CRC64; MEKEIQAIIQ GLGYSEKGVY FPEPDCFESI RDLIRFLRYD THSGLARRLC GEHNLVISDL IPIMKSANTS ERLFDVALRL TINLCQPTIN VFHGKMPEDR EEWRFFTEME KNLCRAKSAF ADSDLMSILH TKISSYFTLE WTDRTESMKL IAERIFVLLG YVLSIGCAEY DGQSMFAEAN SDDRVVMALL NSGIGEVIVN VAATPSEHDF HLSLLHIIAL IVKQREVHNI ITADREESVD EKTKEDEELR KCVEVESQKM LETRRRLGSR HTSFAGSYII KGMKALNPEN DLVLQKVVKK ADRLEHLYGR KAKRRQPKNR RPFEGVEKIH SSALDVRLAL KKFCDSVLLK CYNRLVTGCR DAALNGRRTL SHRNADVHYF LVVRFFMEYR RLRLFPSHLV AATLGKEGFH HVQTQLEQYL DMAYAERREG RVHGLRAQYA LCAYKELLCT LRCMLVSGSN EEKEEAEEAC KHIILMEEYR DLSSSIIRRF TPAIFSKTFL RILVLASHLY IGLLEKCAKS GNLLKVTKRQ KVPKRRTKRR HNRASEESND DGANQIDVDK VWGSICEELS DIVNGYEMPS EDVSPIDMRL QVDDCLYRQF ASLMVQAALR ERRVADAVGL YRTARALWPF EEIFGSDKMQ PEEEFIAMRV IYFSDLTQVE KECKAAREST QGGEVEDGEG NLFDAELEED GRDWEEEEEE DEEATRYVTK EVDFSFDQYL MKFARTDVLK WYVFLLNEYE TNSPELNKAI LKLLHRIAFD LRQAPRLFQI SLFRIFTRLA ERFQNRPFSA IKADRFFRLY EFGFHLLKRF FASYEIIGSK LIPELLFWKG PKECHDLEYG YGSYDALTDE KKSKEMLWTE ELDNEMRSLY DEYVAYDDKP EGIDVVEFIE SNLSRERTRR QIIRQLKSLG LDTFGAKVKL TVATGGSKST MFSASVLEQM KVFADQYRSL PPDQQLVDMI DYIRERLPEQ CNRSRIIKQL KYEGIEYAPN TNARSHKAWS DMLVTELRSL AEQYEELSEK PSCGLIDYIR TRLTEKRTRR DIEAKLVEIG YDPGKLRTSR SLAAATSLRI STKVPKPWSE LLLTELCSLK SQYEELEEDP QCDLADYVIA RLSEKRWRRD VINKLAEIGA DVSNMQKRRR KRRDKKLALS KANEEASGEE RDRSASPLTS GRCRSVASSD ELGLDDNLDD LLIASESGAE KNSYDRRSGR SENARSEQGD LISQDSVGVD SGAVEQANLA TEAKALFGDS SNEDDEEIIV RRGKRMIEDT LSPPFGESIE RSLEPSAPSS KKRIVLSDDE DE // ID F1MQI4_BOVIN Unreviewed; 1216 AA. AC F1MQI4; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 14-MAY-2014, entry version 16. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hereford; RX PubMed=19393038; DOI=10.1186/gb-2009-10-4-r42; RA Zimin A.V., Delcher A.L., Florea L., Kelley D.R., Schatz M.C., RA Puiu D., Hanrahan F., Pertea G., Van Tassell C.P., Sonstegard T.S., RA Marcais G., Roberts M., Subramanian P., Yorke J.A., Salzberg S.L.; RT "A whole-genome assembly of the domestic cow, Bos taurus."; RL Genome Biol. 10:R42.01-R42.10(2009). RN [2] RP IDENTIFICATION. RC STRAIN=Hereford; RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DAAA02013527; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; DAAA02013528; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; DAAA02013529; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSBTAT00000027263; ENSBTAP00000027263; ENSBTAG00000020459. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1216 AA; 140357 MW; C29AA5123E86BA4B CRC64; VDLSMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGSAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLAYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNVLHVP ADLEQEKRID DDASVHDRLL WAIHLSGLDD LLLFLASSPA EQQWSLHVLE IISLMFRDQN PEQLAGVGQG RLAQERRTDV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIIQGLKSI GERDLVFHKG LHNLQNYTSD LGKQPRRVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW SLAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAV SWARRMHLAL KAYQELLATV NEMDVCPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRTR GNLMVQNKRK KRKKKKKALD QSVASGNAPY SPEELEAMWP SLAEQLQCRA QDSELSLDSV VPFDAASEVP VEEQRAEAMV RIQDCLLAGQ APQALSLLRS AREVWPERDV FGAQDISPEE EIQLLKQILL APLPRQQGLE EQGAEEEDEE EEEEEELEVV QVSEREFNFL DYLKRFANST VLRAYLLLLR SYKQNSAHTN HCVVKMLHRL AHDLKMEALL FQLSLFYLFN RLLSDPAAGA YKELVTFAKY ILGKFFALAA VNQKAFVELL FWKNTAVVRE MTEGYGTLDG GSSSRRLPGW SPEEEAQLRE LYLAHKDVEG QDVVDTILAH LKTAPRTRRQ VIHHLVRLGL ADSVKDFQSR KGTQIVLWTE DQELELQRLF EEFQDSDDVL GNIMKNITAK RSRARIVDKL LALGLVAERR ELYKKRRKKL APLSLPNEEE SLHDFCQEDL EEEENVPEKD NEEDEEKEGS EAEQPQGGSI ISAEYLGQSL HQEGFSAPLL WLQNCLIRAA DDREEAGCSQ AVPLVPLTEE NEEAMENEQF QQLLRKLGVR PPASGQETFW RIPAKLNPTQ LRRMSASLSQ AEEEEKLQLG LESKVPGEPG LEEEHQQEEE HQQEEEHQKE HRAHALRTLM LARKKEAGLV SPEEEGTSGG KEQLIMAPKK RQLLDSDEEQ EEDKAPELGV PGIRKKKRFQ IEDDDE // ID F1SLB6_PIG Unreviewed; 1208 AA. AC F1SLB6; DT 03-MAY-2011, integrated into UniProtKB/TrEMBL. DT 03-MAY-2011, sequence version 1. DT 14-MAY-2014, entry version 16. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Sus scrofa (Pig). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Suina; Suidae; OC Sus. OX NCBI_TaxID=9823; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RG Porcine genome sequencing project; RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (MAY-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CU655980; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSSSCT00000000431; ENSSSCP00000000425; ENSSSCG00000000399. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1208 AA; 138627 MW; 36F61EC8D73E9B46 CRC64; LYMMNCELLA TCSALGYLEG DTYHKEPDCL ESVKDLIRYL RHEDETRDVR QQLGAAQILQ SDLLPILIQH RRDKPLFDAV IRLMVNLTQP ALLCFGGVPK EPNFRHHFLQ VLVYLQAYKE AFASEKAFGV LSETLYELLQ LGWEERQEED NLLIERILLL VRNILHVPAD LDQEKRIDDD ASVHDRLLWA IHLSGLDDLL LFLASSPAEQ QWSLHVLEII SLMFRDQNPE QLAGVGQGRL AQERRAAMAE LEVLRQREMA EKKTRALQRG NRHSRFGGSY IVQGLKSIGE RDLIFHKGLH NLQNYSSDLG KQPRRVPKRR QAAQELSIQR RSALNVRLFL RDFCSEFLEN CYNRLMGSVK DHLLREKAQQ HDETYYMWAL AFFMAFNRAA SFRPGLVSET LSVRTFHFIE QNLTNYYEMM LTDRKEAASW ARRMHLALKA YQELLATVNE MDTSPDEAVR ESSRIIKNNI FYVMEYRELF LALFRKFDER CQPRSFLRDL VETTHLFLKM LERFCRCRGN LMVQNKRKKR KKKRKALDQS VASGNVPCSP GELEAVWPSL AEQLQSCAQD PELSLDSMVP FDAASEVPVE EQRAEAMVRI QDCLLAGQAP QALTLLRSAR EVWPEGDVFG SQDISQEEEI QLLKQILWAP LPRQQGPEEQ GVEEEDEEEE EEEELQVVQV SEKEFNFLDY LKRFANSTVV RAYVLLLRSY QQNSMHTNHC VVKMLHRLAH DLKMEALLFQ LSLFCLFNRL LSDPAAGAYK ELVTFAKYIL SKFFALAAVN QKAFVELLFW KNTAVVREMT EGYGSLDGGS SGRRPPVWSP EEEAQLQELY LAHKDVEGQD VVDTILAHLK TASRTRKQVI HHLVRLGLAD SIKEFQRKGT QIVLWTEDQE LELQRLFEEF QDSDDVLGNI MKNITAKRSR ARIVDKLLAL GLVAERRELY KKRRKKLAPS SLPNEEESLN DFDQEGLGEE ENMPEEDSEE DEEKEEGSEA EQAQGGSVLS AQNLGQSLHQ EGFSAPLLWL QNCLIRAADD REEVGCSQAV PLVPLTEENE EAMESEQFQQ LLRKLGVRPP ASGQETFWRI PAKLSPTHLR RVAASLSQSE EEEKLQPGLE PKVPGEQEAE EEQQKEHRAQ ALRALLLARK KKAGLASPEE EGTDGGKEQL KLAPKKRQLL DSDEEQAEEE GESKVPELGA SGIPKKKRFQ IEEDDESD // ID F2PZB4_TRIEC Unreviewed; 1167 AA. AC F2PZB4; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=TEQG_06305; OS Trichophyton equinum (strain ATCC MYA-4606 / CBS 127.97) (Horse OS ringworm fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; OC mitosporic Arthrodermataceae; Trichophyton. OX NCBI_TaxID=559882; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4606 / CBS 127.97; RX PubMed=22951933; DOI=10.1128/mBio.00259-12; RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W., RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E., RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I., RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., RA Summerbell R.C., Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., RA White T.C.; RT "Comparative genome analysis of Trichophyton rubrum and related RT dermatophytes reveals candidate genes involved in infection."; RL MBio 3:E259-E259(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS995757; EGE07232.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1167 AA; 132653 MW; CC658EEA0AA2D76F CRC64; MDGEPFVAQP GDQVVDPEVR SFIYGLVTAL GGSANDEAGR YILGDDALGC LRDLKKWLRF YDEKLNRLDV SRCIAESNLV NGDLVPILAL WDEVKPTDKY KSRITLACLE LLVPLTWPIE IHSEMTVNHH RHTPYLQLAQ VSYKTGILGH PSNSILRSII RIGLPCITTP REERSSRDEG ILKLILYLFR NVVILGATPN LAVEGDEDEA SRSMTINAFH DQDVFALILT LCSNIGEEFT FQDVILLEIL FHLVKGVDVR QLFMDDNQRS ATRIDELKGL MTAEKNLNRD RSKNAPTRHG RFGTMIWVKR DAEKVSSVSG QDVLLNDQAA FDKMDKTKKW NKPRGRRPVI DETSNNFNVQ VHLTSSALNY LRLFVEEFLD SGFNPLMTSI RKAMERESDR LRESSSRHFF FVSSWFLSAE RARREQQEKA RRKATGSARD IEPDSFALVA SVSNQETFIA LNRYMQASLD NKEWQDLSAG MLSFTQTLLT VQEMSKSSLE EDQEIAENIL SRIFYEESTH DRILSTLRGY KGQGFWYLDA CTELAHVFLR MLEQYSKQNV DMQVRSKRIS RRKKKAQNKA QGNQEDEEGE FDNSEDEEEK DRAEAVRNVA ERSFDFKRFC NKFFTQNSVN TFVALTSYYR DLNTEQLKRA HRFFYRVAFK QELSVLLFRL DIIALFTKMI KGPEGLLSSN PAFGEWEELV RQILKKLFKK IDERPELITE LLFSKIPATV HYLEYGQEKQ TVSVASRPAA ELEVKQNYTR TADEKIRIVV SVLVADKCEE LVRWLSEVLD NALKDRKSWE LADLARGVQD AADIADIAPS TPAIEVSAPD EKRKTALFRN GRLRLLFTLA GLEVVGEDVL GTPWSIPGSI PSTELEETRN SIQKHCDDPA TEIDGVDPHK LILRKRIAGK ATNDEATNQV NFGNDSEGED LGLDEILFPP NPRSKSKALK ELKQKRRKKT DADEDNELDE ETLNARRFAR EQNALERQRK IKSSLFVNAS DDETDDEADQ EFFAREAERR KRQAQLVEEA MDIDGLGSTL LGDSTKKSRG KRKQAISSES DGEDVSAGQR KRARSEDLGS GSEEDEVLGA APRRKAQTPP TSTEDDLIYD VGEKSQWTLT AVDRPSKPTG AIEQKIDDDD EDDEPVTTTR SRRPKVMAGF VVDSDSE // ID F2QQM9_PICP7 Unreviewed; 1185 AA. AC F2QQM9; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 03-SEP-2014, entry version 13. DE SubName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=PP7435_Chr2-0008; OS Komagataella pastoris (strain ATCC 76273 / CBS 7435 / CECT 11047 / OS NRRL Y-11430 / Wegner 21-1) (Yeast) (Pichia pastoris). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Komagataella. OX NCBI_TaxID=981350; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 76273 / CBS 7435 / CECT 11047 / NRRL Y-11430 / Wegner RC 21-1; RX PubMed=21575661; DOI=10.1016/j.jbiotec.2011.04.014; RA Kueberl A., Schneider J., Thallinger G.G., Anderl I., Wibberg D., RA Hajek T., Jaenicke S., Brinkrolf K., Goesmann A., Szczepanowski R., RA Puehler A., Schwab H., Glieder A., Pichler H.; RT "High-quality genome sequence of Pichia pastoris CBS7435."; RL J. Biotechnol. 154:312-320(2011). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CBS 7435; RA Kueberl A., Schneider J., Thallinger G.G., Anderl I., Wibberg D., RA Hajek T., Jaenicke S., Brinkrolf K., Goesmann A., Szczepanowski R., RA Puehler A., Schwab H., Glieder A., Pichler H.; RT "High-quality genome sequence of Pichia pastoris CBS 7435."; RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FR839629; CCA37707.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1185 AA; 136115 MW; 48BAC199DBC9C94D CRC64; MSLYAEDPEL DDFIIDNEPS GTHHIVESSS DEEERFTEKS SGPIKQARST QPELQNHDEE LRKRVIRSHI AILCSSLGGI DHSTESKLSI YKLGGEALVC LKDIKRWIRT VDHEMNNWDV ASACADCNLV PNDLIHIMTQ WELDNQGKKV ENPKYWESIV VSSLELLVML TNPLVLEFEK TDEKKIVLYP KLKKAHLTYK NRILNFQGGL TLKAVLRILL PLLVSNKRST RDLKVMYLCL TFIRNVIRIE PADARINSKK TTKQLNISSN YPVGVSPDDV DVNRVMIILK KTKVLSLILT LTSNADKAYN DTMLHQLCLE CLYYLLNGIK VSSFILGEPQ NEHDSSMTEA GLELSDLVSK EKNIFDGIKR NHSSRHSNFG TLLSLQRGNE RITISGSPKD LLATLDKTKS HSNSRTYTRI AKNESTNRDL DSQLRLHKAK RLDSEGLKIL IEFLQSFMEE SFDPFFSKLI HTYSSDDNIR SYLMYAYFYV LQWILEYFQG LKKKDFYNIA SAFDHSNVIL ILRKVSEYHD LKEFNMCYVL IGCLDELLSN ACFMLSTNDS QLIDRAEGLL NSIVGQEAYL ELFISIVSSA HKVSTQFVDK AAQFLSTIFK STEAMVRFYD SDQVIIQKSK STKKRNSRIA ATEEEDNEPG EVDDIQMRTL AFKKKADIKS IRTKLIRNET VYLFISIWER LDDVDAAHFK LALHFFYDVF VKYELVLHLY RLDFLKTLYW VNANHLVLPI GKSTRRDLQS FSKYFMSKLY QLMNHSKEIL VEMPFCSLNP DVSIRQYFLT GEKPDVHEKT AREYKVGKLE FTEELNLEQK IGILVSLLKA LNLDLVEWLK HNVETIVDSM SSWNDRDIVT GEDLTSKDED LYILQASNKA YNSAIRRNPT FRKLLELVGY DIPTHTGMKC VLQKHIDQSS LEICLSFIKK YLEEDYVPSN HAEVEELVNL KKPAPNSRNG TDEFNGADNQ HNDQEDDLFV NESDDDNQIE FEIGENGQRR IVNDNLDIIE QQLKFNERRN RGVARPPSKR AKRNRVISSE DEDISDGLSS LNKKVKRSKR KQARRIRKTI FDSNNEIGEE SSGEGAKRKP SNLDLNIKSS EYIDDSDLEL TDEEVFFFRE DTLRSMLNES NGQLTAAQLQ ELSNITINHL KSRSLTGGDL ENLTIKNSIA KEGTPISFAQ PIDDE // ID F2S5Y1_TRIT1 Unreviewed; 1133 AA. AC F2S5Y1; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=TESG_06344; OS Trichophyton tonsurans (strain CBS 112818) (Scalp ringworm fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; OC mitosporic Arthrodermataceae; Trichophyton. OX NCBI_TaxID=647933; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 112818; RX PubMed=22951933; DOI=10.1128/mBio.00259-12; RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W., RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E., RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I., RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., RA Summerbell R.C., Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., RA White T.C.; RT "Comparative genome analysis of Trichophyton rubrum and related RT dermatophytes reveals candidate genes involved in infection."; RL MBio 3:E259-E259(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG698517; EGD98980.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1133 AA; 128740 MW; 580CD5ED31922169 CRC64; MDGEPFVAQP GDQVVDPEVR SFIYGLVTAL GGSANDKAGR YILGDDALGC LRDLKKWLRF YDEKLNRLDV SRCIAESNLV NGDLVPILAL WDEVKPTDKY KSRITLACLE LLVPLTWPIE IHSEMTVNHH RHTPYLQLAQ VSYKTGILGH PSNSILRSII RIGLPCITTP REERSSRDEG ILKLILYLFR NVVILGATPN LAVEGDEDEA SRSMTINAFH DQDVFALVLT LCSNIGEEFT LQDVILLEIL FHLVKGVDVR QLFMDDNQRS ATRIDELKGL MTAEKNLNRD RSKNAPTRHG RFGTMIWVKR DAEKVSSVSG QDVLLNDQAA FDKMDKTKKW NKPRGRRPVI DETSNNFNVQ VHLTSSALNY LRLFVEEFLD SGFNPLMTSI RKAMERESDR LRESSSRHFF FVSSWFLSAE RARREQQEKA RRKATGSARD IEPDSFALVA SVLNQETFIA LNRYMQASLD NKEWQDLSAG MLSFTQTLLT VQEMSKSSLE EDQEIAENIL SRIFYEESTH DRILSTLRGY KGQGFWYLDA CTELAHVFLR MLEQYSKQNV DMQVRSKRIS RRKKKAQNKA QGNQEDEEGE FDNSEDEEEK DRAEAVRNVA ERSFDFKRFC NKFFTQNSVN TFVALTSYYR DLNTEQLKRA HRFFYRVAFK QELSVLLFRL DIIALFTKMI KGPEGLLSSN PAFGEWEELV RQILKKLFKK IDERPELITE LLFSKIPATV HYLEYGQEKQ TVSVASRPAA ELEVKQNYTR TADEKIRIVV SVLVADKCEE LVRWLSEVLD NALKDRKSWE LADLARGVQD AADIADIAPS TPAIEVSAPD EKRKTALFRN GRLRLLFTLA GLEVVGEDVL GTPWSIPGSI PSTELEETRN SIQKHCDDPA TEIDGVDPHK LILRKRIAGK ATNDEATNQV NFGNDSEGED LGLDEILFPP NPRSKSKALK ELKQKSQTLN ARRFAREQNA LERQRKIKSS LFVNASDDET DDEADQEFFA REAERRKRQA QLVEEAMDID GLGSTLLGDN VSAGQRKRAK SEDLGSGSEE DEELGAAPRR KAQTPPTSTE DDLIYDVGEK SQWTLTAVDR PSKPTGAIEQ KIDDDDEDDE PVTTTRSRRP KVMAGFVVDS DSE // ID F2ST76_TRIRC Unreviewed; 1172 AA. AC F2ST76; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 13-NOV-2013, entry version 8. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=TERG_05678; OS Trichophyton rubrum (strain ATCC MYA-4607 / CBS 118892) (Athlete's OS foot fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Arthrodermataceae; OC mitosporic Arthrodermataceae; Trichophyton. OX NCBI_TaxID=559305; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4607 / CBS 118892; RX PubMed=22951933; DOI=10.1128/mBio.00259-12; RA Martinez D.A., Oliver B.G., Graeser Y., Goldberg J.M., Li W., RA Martinez-Rossi N.M., Monod M., Shelest E., Barton R.C., Birch E., RA Brakhage A.A., Chen Z., Gurr S.J., Heiman D., Heitman J., Kosti I., RA Rossi A., Saif S., Samalova M., Saunders C.W., Shea T., RA Summerbell R.C., Xu J., Young S., Zeng Q., Birren B.W., Cuomo C.A., RA White T.C.; RT "Comparative genome analysis of Trichophyton rubrum and related RT dermatophytes reveals candidate genes involved in infection."; RL MBio 3:E259-E259(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG700653; EGD89436.1; -; Genomic_DNA. DR RefSeq; XP_003233805.1; XM_003233757.1. DR GeneID; 10375697; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1172 AA; 133306 MW; 5531FB697CA8DF13 CRC64; MDGEPFVAQP GDQVVDPEVR SFIYGLVTAL GGSANDEAGR YILGDDALGC LRDLKKWLRF YDEKLNRLDV SRCIAESNLV NGDLVPILAL WDEVKPTDKY KSRITLACLE LLVPLTWPIE IHSEMTVNHH RHTPYLQLAQ VSYKTGILGH PSNSILRSII RIGLPSITTP REERSSRDEG ILKLVLYLFR NVVILGATPN LAVEGDEDEA SRSMTINAFH DQDVFALILT LCSNIGEEFT FQDVILLEIL FHLVKGVDVR QLFIDDSQRS ATRIDELKGL MAAESNLNRD HSKNAPTRHG RFGTMIWVKR DAAKVSSVSG QDVLLNDQAA FDKMDKTKKW NKPRGRRPVI DETSNNFNVQ VHLTSSALNY LRLFVEEFLD SGFNPLMTSI RKAMERESDR LSESSSRHFF FVSSWFLSAE RARREQQEKA RRKATGSARD IEPDSFALVA SVLNQETFIA LNRYMQASLD NKEWQDLSAG MLSFTQTLLT VQEMSKSSLE EDQEIAENIL SRIFYEESTH DRILSTLRGY KGQGFWYLDA CTELAHVFLR MLEQYSKQNV DMQVRSKRIS RRKKKTQNRA QGNQEDEEGE FGNSEDEEEK DRAEAVRNVA ERSFDFKRFC NKFCTQNSVN TFVALTSYYR DLNTEQLKRA HRFFYRVAFK QELSVLLFRL DIIALFTRMI KGPEGLLPSN PAFGEWEELV RQILKKLFKK IDERPELITE LLFSKIPATV HYLEYGQEKQ TVSVASRPAA ELELKQNYTR TADEKIRIVV SVLVADNCEE LVRWLCEVLD NALKDRKSWE LADLARGIQD AADIADITPS TPSIEVSAPD EKRKTALFRN GRLRLLFTLA GLELVGEDVL GTHWSIPGSI PSTELEETRS SIQRHCDDPA TEIDGVDPHK LILRKRVAAK STNDEATTQV NFGNDSEGED LELDEILFPP NPRSKSKALK ELKQKRRKKT DADEDNQLDE ETLNARRLAR EQNALERQRK IKSSLFVNAS DDETDDEADQ EFFAREAERR KRQAELVEEA MNIDGLGSTV LGDSTKKARR KRKQTISSES DGEDVSTGQR KRARSEDLGS GSEEDEELVA PFRRKAQTPP TSTEDDLILD MGEESSAPDF QWTSTAVDRP SKPTGTIEQN IDDDDEDDEP VTTTRSRRPN VMAGFVVDSD SE // ID F2TNU0_AJEDA Unreviewed; 1195 AA. AC F2TNU0; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=BDDG_07848; OS Ajellomyces dermatitidis (strain ATCC 18188 / CBS 674.68) (Blastomyces OS dermatitidis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; Ajellomycetaceae; Ajellomyces. OX NCBI_TaxID=653446; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 18188 / CBS 674.68; RA Cuomo C., Klein B., Sullivan T., Heitman J., Young S., Zeng Q., RA Gargeya S., Alvarado L., Berlin A.M., Chapman S.B., Chen Z., RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., RA Heilman E., Heiman D., Howarth C., Mehta T., Neiman D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA White J., Yandava C., Haas B., Nusbaum C., Birren B.; RT "Annotation of Blastomyces dermatitidis strain ATCC 18188."; RL Submitted (MAR-2010) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG749479; EGE84903.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1195 AA; 136849 MW; 185DD5E290137BD0 CRC64; MESESVQPVQ VVDPEVRAYV YSLITALGGS GSSDTGKYVL GDDALACLRD IKRWLKFYDE KANRMDVARC LAEANLVNRD LIPILTLWGD DIHDEKHKSR IALACLELLV PLTWPLEIHS QMTVNHHRHT PYLQQSQVLY KRGILGNDTT AILRTIIRIA LPSMTTPRSD RSSRDEGILK LMLYLFRNLA IITPSPHLAR EGDEEEASKS ATINAFQEQD VFALLLTMCS NMGEDFVFQD VVILEILFHI VKGVDIEKLF MNDTQRSIAG TDDLEALLDK ESHLKREYAK TAPTRHGRFG TMIWVKRDDE KVSTVSGQDV LKDDWTTMLK MDKTKKWNRP KHRRGGVDMS VNNFNVPSPL TPSATKNLRT FVEEFLDSGF NPLFSHLRKA IEREADRVTE STPRQFFYVI SWFLEAERVR RTRQQELRQQ NPNPARDIEP DSFQLVASVL NQETFIALNR HMQNCLDFKD WQDLNASMRC FTQILLTVQQ MFHSDISEDQ DIAENILSRI FYEETTHDRI LTILRGYESQ GFWYLDACTE LAHVFLRLLE QYSKQNEHMQ IRSRRRARRK QRKEAVANPE NPETQNHDES EAEDLAMEDA TRTIVERSFD FRRFAAKFCT QKSVNTFLAL TTHYRELNEE QLKRAHRFFY RVAFKQELSV LLFRVDIISL FYRMIKGPGG LDSAKSVYAE WEELTRRVIR KLIKKLEQRP ELITEMLFSK INATVFYLEY GHERQTVSNS KPAAELEVKP GAATTLDSRL GIVVAALHLE GKENLVQWLV KTLDTAVNER RCWELEAESR QTESGGEHPP SPPSIAVIPL DDACRTAMFK NGRFRLLMTL AGFERLGVED TLDSSWIIPS SLSAKTLEET QKSVEKHSEN PPTEFDGLEP RDLLRRKRDV DTTMPSHGRP QGEVDFGNDS EGEDDIDGIL FPPNLRIRTG TLDELKKKRL RRGKKNKEDG DGPDEAALEA RRLARQANAL ERQRKIKSSL YINASDEESD EEADREFFAR EEERRKNQAR RIKQALLSGT AGGDKATGQK SSSKGRKRKS TANGDENNKR QRSDPLLDSD DEDNAINIDN PEDDDDEDVM MATQETPSSS SETESISMAQ PERRSENTTP PTSTERNPIF GMNDDDYFDN PFYFASLADK DKTGGDKGVG SDGREEEEQV KMPARQRRML GAFIIDSDSE SEVGE // ID F2UT00_SALR5 Unreviewed; 1428 AA. AC F2UT00; DT 31-MAY-2011, integrated into UniProtKB/TrEMBL. DT 31-MAY-2011, sequence version 1. DT 11-DEC-2013, entry version 11. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=PTSG_13166; OS Salpingoeca rosetta (strain ATCC 50818 / BSB-021). OC Eukaryota; Choanoflagellida; Salpingoecidae; Salpingoeca. OX NCBI_TaxID=946362; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 50818; RA Russ C., Cuomo C., Burger G., Gray M.W., Holland P.W.H., King N., RA Lang F.B.F., Roger A.J., Ruiz-Trillo I., Young S.K., Zeng Q., RA Gargeya S., Alvarado L., Berlin A., Chapman S.B., Chen Z., RA Freedman E., Gellesch M., Goldberg J., Griggs A., Gujja S., RA Heilman E., Heiman D., Howarth C., Mehta T., Neiman D., Pearson M., RA Roberts A., Saif S., Shea T., Shenoy N., Sisk P., Stolte C., Sykes S., RA White J., Yandava C., Haas B., Nusbaum C., Birren B.; RT "Annotation of Salpingoeca rosetta."; RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL832997; EGD81259.1; -; Genomic_DNA. DR RefSeq; XP_004987655.1; XM_004987598.1. DR GeneID; 16068197; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 2. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1428 AA; 161136 MW; 1A1F985DBDC1C518 CRC64; MGDTLEWADA LLQLCSALGL RDVDETTPDV YRKGAECHEV LKDIMRNLRI DVRNSERPVL RQLGQFEFLQ KDLMLLLIQY ASDENEKQLM VTLLRVMTAM TLPAYIVFQY ETQGQSLAGL EKTLAYTQVN EYLTKYKDAF VQSYEMTATA EEREEGQPAR YHCYAPLRAL LQLLYEPLTA EDRTDQDNAM IELILTLIRN ILHAPNPPSA GGSETLHDRA VRAMEESGII DVVMSMCHDI TEYYSFKMIV LEILMLLYRE QTAESLYSCV YETKTHASTE HTDDDSSANT MAANVRPAAA PRGTTRTHAR RPAKKKTRTR QYGSRHTRFG GSFELQSVAG AATSTRVVSS AVLRRAEKIS EEGKTHRARK PIVDAEAVSK HTSPLAVRVC LYKHAVSVVR DCFNSVIPLV EDELRRMEMK DLELIHADRK HYLQFIRLFM EFHRLQLETV LQKKKRDGVP ISEEEGYAVS VVGACLGQQT IDHIQSFVQE YYQGLQQYPV DGQLWGRRLH FAIRAFHEVL MYIQLLASSP NQDQRDFASS MTSRIFYHQE FLDIFPKVII SFNARKESRE LLDDIIVTVH AVLKLLSTST VRLFVKRKKR GGRRKKKQQK GSEAQQQQQQ REEEEQQGEH PQQDEEGEQR QQHQQQQDEA SADQNAANVQ PTAAGGDGEN TTTAGTDGDG DGDGDGDGDE NAVDKENSNA NATGTAAGDD ISTAHTDTTA DEGHNAEKDS ALESLFDDEE GGVSDDHTPA KRNSSGGGGS VAETDLAQQL FGDEEEQRAI REELEDEVEM HQAESRIQEA EFQFSKYLEL FKDYRIVSAY CEALRTYNNN PPSLNHCIVK MFDRMSRQDK LDARPLFYQL SHLRLFRAIL DDPATKDSPD LKQIRGFIKL AVVKPLVEEL QQNPVLFVEI LFSKSNMDVD EIKYGHVEAM RRRRTRSRVW GPDDDKTLRQ LYSTHKDDPN MIQHMIDVFE DRSERAIKAR LTKLGLTVSS SKEWSEQEDS TLRRLFEEHQ HDDDPVEGIL QSDELPENKL VRTRVLIRLR KLGLYQRQRY KHAKEAWTEE ELSALQEVWK ECSDLPLLGK LEVLTGDPRL SSRRERAIRQ KLIELDLLQD KRRKPKQQRS TQQASATAHN AMGSTHDGAG GDESDDDSGN NDDDDDDDYD DDDEEWLEKR KPKGKPSRRE QRHKRRSGQQ HNTQYDDEDD SGDQHARASK PDARAADGDD DDSDGNDGGG SKSSYIQAFR RQRGRRLGSQ GLAKRREAAR PKVRRVVPLA DDDDDDAAVP SSRVQPTTAA AADAADDDDN DGSDGDNDNA TVAPAQPARS IRRVITSDDE DDSDDEPGRG GSDGDDDQEP TSTAVSTAVT PRRKTAPLNL ILDDDDDDED DGGAGSDAEL ESNPFRAEKT NEDKDENPNK RAKTAAAEEA EDNEIAAE // ID F4PDL4_BATDJ Unreviewed; 862 AA. AC F4PDL4; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 14-MAY-2014, entry version 8. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=BATDEDRAFT_92367; OS Batrachochytrium dendrobatidis (strain JAM81 / FGSC 10211) (Frog OS chytrid fungus). OC Eukaryota; Fungi; Chytridiomycota; Chytridiomycetes; Rhizophydiales; OC Rhizophydiales incertae sedis; Batrachochytrium. OX NCBI_TaxID=684364; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JAM81 / FGSC 10211; RG US DOE Joint Genome Institute (JGI-PGF); RA Kuo A., Salamov A., Schmutz J., Lucas S., Pitluck S., Rosenblum E., RA Stajich J., Eisen M., Grigoriev I.V.; RT "The draft genome of Batrachochytrium dendrobatidis."; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL882895; EGF76699.1; -; Genomic_DNA. DR RefSeq; XP_006682691.1; XM_006682628.1. DR GeneID; 18244600; -. DR OMA; THANQNT; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 862 AA; 97921 MW; 4313B4BD5D7D52B7 CRC64; MAEVDEYFDN HVLSVCAALG GYETVEKGVE PVYVPGDDSI ACLRDLKRFL RTAEQTKDRH VHNLLRKWNV LQNDLLPLLI TSVRSNNLKV AALVCELLVP LTWPYDQNGQ SKYQDEIKEY QEAFLKDNVI SSVLTVLIHL FSIPYKQRAE NDHTRLRLFF SLFRNLIAAN DVQVAVTASA ESHWRSVHQE RLIIQLEKDG IIDLLLSICG SLSSEEFEGW NVLILEIIYM IFHRRDISEL FIEKPKGEQL ATLLKKEQSL KTACSNPKHS RHSRFGGTLT VSLPNGSRIN TRDITTKDVL KDIAITDIPR GKTRNLAAID SKISIESPTV RKLFGKIAST FVSDAFNDLA ISLKRDFDRE KTSLKDSDNM HYLWLCQFAF SFRRMSCIGS TPIGVDSILG VFNVPNLAFT IRRLTASRDE KNPLETTQCL RFLDELLLVV EELSQSSNDE LCDLSTQLIS ALYYEHGNAL LLRSLCKEFK QHTKSYLEAL VACIDTLINV TKRNTAKRGF LITRKKVKKL QNDAQNTEDQ GRSWFHIMYN ESDTEESRHQ EQYTENAFDF KSYVAGFASE STVVTYCKLL KYYPDLSPTI ATKILSMFKR LFCEQKYHEP FFKLSVLALL YHVSTKNVGS TAALLGKEFE EFTKLVSKAL ITKISRNKDR GPLEMINILF SSTSGNVDNS QTTKLDEDVL RNSISDTIFC VAALEYWLGT AMRQDIKATL FKELRDSFTA ALQHTTMPAF SEMIQKLIHT SDELQILFEA ACLSLNHEHG SLSIPVMWSN SDLVAAIQTI DILQGHKRSA RPRSGSSFKK AKTAEPVNNL SSKFVEESDE DEETTAIFFE REAELRKAAE NAWKMQASKN AV // ID F4PIF7_DICFS Unreviewed; 1636 AA. AC F4PIF7; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 16-OCT-2013, entry version 6. DE SubName: Full=Timeless family protein; GN ORFNames=DFA_03635; OS Dictyostelium fasciculatum (strain SH3) (Slime mold). OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium. OX NCBI_TaxID=1054147; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SH3; RA Gloeckner G., Schaap P., Noegel A.A., Felder M., Eichinger L., RA Heidel A.J., Platzer M.; RT "Living fossils from the dawn of multicellularity."; RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL883006; EGG25386.1; -; Genomic_DNA. DR RefSeq; XP_004363237.1; XM_004363180.1. DR GeneID; 14876934; -. DR KEGG; dfa:DFA_03635; -. DR KO; K03155; -. DR GO; GO:0004553; F:hydrolase activity, hydrolyzing O-glycosyl compounds; IEA:InterPro. DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. DR InterPro; IPR001579; Glyco_hydro_18_chit_AS. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. DR PROSITE; PS01095; CHITINASE_18; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1636 AA; 185438 MW; 43BF0DAA1EE0F6CA CRC64; MDRDQVEIIR IIDELGEWKH ADDPKRKRFI KGRECKEATA ELYRYLRRFD SEIYSMLGPF NIIQSKLIPI VVSYSNDLPL MVSILKVLVR MTIPVPTISE GYLKQTGYLL DYKESMINKS FISTLIVILK EPLRRLEVLD EGKNEDYYII ELVLSLIKNL LVIADPEPQA NVSIKDYRCF LHESFILILE ECKFLELFLI LAQNIRENKI FKSLSIYSFL LLEIFAFIFK NESPDTIWSN QPRHFINIDD ISSIDNNNQN NNNIKKVEAP KEDDRLAKLL AQDAKLKAAS RKKTSTSRFV GAFKKENKIS STPDALNDVT AAKIRLNALP NASLQSNAPV IGRLKASSTR RMAGPSTYKV RVILKSWAEQ FLDGCYNTLM ELVSEELERA ESGLTSNTIL ATDRINYLSL THFFTGFSLV LLQQNYGQQQ QQEEGGEEEE KKKEFMNNII GSLSSTLSLN TFNFVFSCCL MSRQTFVPFG TKNNANATDD GGLTEMSIST MKEMVAILHF MGVSGNSKME EISMNIQSKI YYERDVFLKR VVEMIQIYHP KKYPQSVLTE LTELAHTSIS MVERFCQVNN SISIHSHRRA KKSSTNKGLV EDVDEEKDQD GKVMDIDKDF IDDNVETKKK KKDENINGNE NVNGVDIDIE MKDQVVDDEK KETNGEKKEE KEETNGKKKA EGDQKNEKKE EGEGEEGEED IIRMKREDDE DEYHGQSTSI SFISFLSDFA KPDIVNNMCT LLGNYHYNSD KINYQLVSIF QRFRTELDLE PMFYKLSIFY CFYNLLRDPL IAMDSKAIDM VGFVKTVVNN FFKYAETNPS LLLHLCLPKT KSTSGIIMSS VIDEDMYGAG YGGGEQKKSR SDKIKQEEEY DQEEAHLGAE DDNENIVLNE RRPPKSKNNA SDSEGEENNF SDEEQIRHFK SLQESVDTAT VTRRVKNLLK LPDDSGKAFL KWIEQELYDA IKIRGEQLKL DRFSPFVLKH LSLTAKFPSI LINRNVVDLL LTSFKFRGSA TTKAINRTFS IPENRLFSPS YLSFLVKLIN DTKSDQKKAT KKKQVSKDEE EEEEELEIIE NELEKEKVIE KELEKDEEDE EETELEEEEE LEIIYNAKKD DSDFDLSDGE STNNQKANVS DQEDEEKPTT SLPTTTTGKK LRKANKIISQ QEEEEDVDDG FGDISIEETI AVEKMEEEED DDDDEIIETS QKKQPSKIIQ EQESDISESE QVSTSEPIIK MDLEKKEKEI IEEETTTPSK KITPKKTTPK KSTPTKATTP PPTKKNLSKV TQVEKTVSDG ESDDDDDEEK PTTNVNKNNK KSLLTKRKIL PEQKDNKSNI KKQKGKEGAQ KVVEKESSEE SSSSGSEAIK KKQPTPTKKP SKVVSSDDSS SSSSSSEDEK TKPKKTILTL KKPYTSPKKA APSPKKIVSS DDSSSDSSDS EQEKKKKKKP AVNGKSKPSK SSDSTSSSEE EEQPTKPFKK STTATTKKAK AKVVSSDDSS SSSEEEEVKK KKKKVIPLKK PSKIVSSDDS SSESEAEQPK RVQVKIPLKK NNKKAPIKKP VKKVVSSDSS SSSSDEEEIR KKKKNIAPQK KKYTVADDSS SSSSEEEVKK KRKVVVPKKN VPTKKKNKKV VSSDDSSSSS SDSSSD // ID F4R2Z6_MELLP Unreviewed; 1135 AA. AC F4R2Z6; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 09-JUL-2014, entry version 7. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=MELLADRAFT_114767; OS Melampsora larici-populina (strain 98AG31 / pathotype 3-4-7) (Poplar OS leaf rust fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; OC Pucciniomycetes; Pucciniales; Melampsoraceae; Melampsora. OX NCBI_TaxID=747676; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=98AG31 / pathotype 3-4-7; RX PubMed=21536894; DOI=10.1073/pnas.1019315108; RA Duplessis S., Cuomo C.A., Lin Y.-C., Aerts A., Tisserant E., RA Veneault-Fourrey C., Joly D.L., Hacquard S., Amselem J., RA Cantarel B.L., Chiu R., Coutinho P.M., Feau N., Field M., Frey P., RA Gelhaye E., Goldberg J., Grabherr M.G., Kodira C.D., Kohler A., RA Kuees U., Lindquist E.A., Lucas S.M., Mago R., Mauceli E., Morin E., RA Murat C., Pangilinan J.L., Park R., Pearson M., Quesneville H., RA Rouhier N., Sakthikumar S., Salamov A.A., Schmutz J., Selles B., RA Shapiro H., Tanguay P., Tuskan G.A., Henrissat B., Van de Peer Y., RA Rouze P., Ellis J.G., Dodds P.N., Schein J.E., Zhong S., Hamelin R.C., RA Grigoriev I.V., Szabo L.J., Martin F.; RT "Obligate biotrophy features unraveled by the genomic analysis of rust RT fungi."; RL Proc. Natl. Acad. Sci. U.S.A. 108:9166-9171(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL883090; EGG12538.1; -; Genomic_DNA. DR RefSeq; XP_007403476.1; XM_007403414.1. DR EnsemblFungi; EGG12538; EGG12538; MELLADRAFT_114767. DR GeneID; 18925465; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 2. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1135 AA; 129221 MW; 261AFDCD871EC453 CRC64; MPLKKAERKL ESSKAHEARM ERRKILEPAV LAVVSALGGC LKDLKKFWRL DEDDDDRTVA RLLYDSQILP KDLLPIITSL DLDDKKDFRV SLLCSDLISA LTWPIDIASE LKEMNELLDQ ETKRELKQID FSGLISAQLS YKRDILNAGA LAHIFRLIVP SLQKALKDKP CPIGESSTSA DDYQLQSELI IQMSRFGIFD FLIHLSHGAN RFDVFGAWNM IVLDIWHLLF RGMNAEDLVD AESFFKTNEE GQTVKTLSAS ARRLDALLAE EEQEKRRQAR KAPSRHSRFG TTISVHTEGQ KYNLHRQSDI TTSLEHALDL RKKAKKKPVR LRDELGTPTE LTPDAMKVLR KVATEFIESA FNHREKRVGI LPDSEEGHDF DLIASLIEPG CMRYILEKIK ANVEEKPMPA VEVHAAVNSL LYQLLVIDGL MASGVASYID AATLIQDKLY YDETSLEIVI QLLSSYTTQS HKFLDNIIFL ATVFLKMLER HSKSQDHMFV RKKKPNKKSQ ANGKGNAIEG ELENAEAGLG IGDEEEAEFE AMEARNAQRY AEHKFEFEKF QAKFAREPVL NTLLVYLTGH REFKDPEQLK RVVRLLHRIA VNAKSDGLFF KVSTFDTLNT LLEDRANSPR NPVYDDLWKL IDYILKQFFK SIRQNPFLLV ECFFPSRKTK GGRTRNIENS DSDADSLVLT KSKKKPLKLP AEIVVKPGLT WSQKLGVAIG LLVDDNKSDL VEQVKDTLRL ASAARTAIVL ITDGSPDEDE NIDIRAWLDE PNEELSEALK EKFAKPSAAA LEKFEDHEVR SEDQDYDKAL GRDPQLHLLL RLLSWDNTED EGRLQWTIPK TRLHTELNVD LKIIDYFLLN PLDHNGKSAA ELVKKKRKTQ GSRRTRRRET SADLNEEERA LDGDSDEDEE ESRKKRKAKK QQEVKQYQSA QFIADSDDED DAERDARFFE QERLLRERIN QGAILGMGAS KADSNPISTR KIRAKPAKRN RQIKKVARSK EIGINEDDAG NDEMDVDMLD GEQDQVNLTS EKSVLREVSP ELSQDEEENE ESSSDEIDIR PQTTTTTTID ITSPTRSSTS SAQSKSVEII NRKRNLVSSI KLGGEEDEDE IDELEDSPRR VKSRKILVID SDEEE // ID F4WT13_ACREC Unreviewed; 643 AA. AC F4WT13; DT 28-JUN-2011, integrated into UniProtKB/TrEMBL. DT 28-JUN-2011, sequence version 1. DT 03-OCT-2012, entry version 5. DE SubName: Full=Protein timeless-like protein; GN ORFNames=G5I_08987; OS Acromyrmex echinatior (Panamanian leafcutter ant) (Acromyrmex OS octospinosus echinatior). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Vespoidea; Formicidae; Myrmicinae; Acromyrmex. OX NCBI_TaxID=103372; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21719571; DOI=10.1101/gr.121392.111; RA Nygaard S., Zhang G., Schiott M., Li C., Wurm Y., Hu H., Zhou J., RA Ji L., Qiu F., Rasmussen M., Pan H., Hauser F., Krogh A., RA Grimmelikhuijzen C.J., Wang J., Boomsma J.J.; RT "The genome of the leaf-cutting ant Acromyrmex echinatior suggests key RT adaptations to advanced social life and fungus farming."; RL Genome Res. 0:0-0(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL888331; EGI62626.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 643 AA; 75416 MW; 18AC7E4DCEBC7D88 CRC64; MDFRSTVTFT MVDTIVIRVY YAELNSHCYC NTLYATSFPS PLTFLSLELL INLTSSAFVI YNEQIPTEKT MRSFYQQIVT YLQEYKAALT DENVWLAVAG RLGILFNIDN KEREEENELT IERILAFIRN VLQVPPNDND KRADNDATVH DELLFAFHAS GIVDIILFIV SNKNEQQYHM QILEIISLML REQNASLLAA SGLQRSNAER ENDEASLVAL RQKELREKIY KVKKYAGSRH SRFGGTYVVQ NMKAIGENQM ICHKPYQKIE AVEFGHDKKR VKRRRDKMSL QDAKEERTSV LSVRLFLKEF CVEFLSGAYN PVMKFTRSCF INDPHGQAVE AAVYLWALRF FMEFNRHYKF QVKYVSETIS TEVFYLVQRQ MDQYYEMIIV DKKKIPLWSR RLHLALKAYQ ELLNTLMAMD KNSDDGVRES SKIIKSNIFY VPEYRETILS QLLCFDEVKM SRQYLVDLIT TIHTFLKMLE HYCQKGQRHL VVQQIKLKRK KAKKGKKSTQ ENVTTAPTLE ERWDIIGPEL SAVMRDAIIP VVVPFDATLD TPIDDQKTDA MKRIQKLMRQ RNLEQAVGLL RAAREIWPEN DCFGKVDILP EEEFLALREI FFTDLGGELF YFQFYIFDNE HKHFLIMFLR SYK // ID F6H6I1_VITVI Unreviewed; 139 AA. AC F6H6I1; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 19-FEB-2014, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN OrderedLocusNames=VIT_16s0050g02170; OS Vitis vinifera (Grape). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; Vitales; Vitaceae; Vitis. OX NCBI_TaxID=29760; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Pinot noir / PN40024; RX PubMed=17721507; DOI=10.1038/nature06148; RG The French-Italian Public Consortium for Grapevine Genome Characterization.; RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., RA Casagrande A., Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., RA Legeai F., Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., RA Poulain J., Bruyere C., Billault A., Segurens B., Gouyvenoux M., RA Ugarte E., Cattonaro F., Anthouard V., Vico V., Del Fabbro C., RA Alaux M., Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., RA Moroldo M., Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., RA Durand E., Pesole G., Laucou V., Chatelet P., Merdinoglu D., RA Delledonne M., Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., RA Pe M.E., Valle G., Morgante M., Caboche M., Adam-Blondon A.-F., RA Weissenbach J., Quetier F., Wincker P.; RT "The grapevine genome sequence suggests ancestral hexaploidization in RT major angiosperm phyla."; RL Nature 449:463-467(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN595243; CCB47783.1; -; Genomic_DNA. DR EnsemblPlants; VIT_16s0050g02170.t01; VIT_16s0050g02170.t01; VIT_16s0050g02170. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 139 AA; 15709 MW; BAB512499CB2128D CRC64; MDMEGLSVIC AGLGSIDEDD GGNRIGYAKT DYCLDNLKDL LRFLRRDDPQ SRSVFKQVCK WNTVSKDLIP IIEHCQDDRN LVLNAVKVLV FLTMPIEASS NDISQQIEYL WGLKSSITRS NTIAVVMSLL ESPLENLEW // ID F6H6I2_VITVI Unreviewed; 1143 AA. AC F6H6I2; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 19-FEB-2014, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN OrderedLocusNames=VIT_16s0050g02160; OS Vitis vinifera (Grape). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; Vitales; Vitaceae; Vitis. OX NCBI_TaxID=29760; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Pinot noir / PN40024; RX PubMed=17721507; DOI=10.1038/nature06148; RG The French-Italian Public Consortium for Grapevine Genome Characterization.; RA Jaillon O., Aury J.-M., Noel B., Policriti A., Clepet C., RA Casagrande A., Choisne N., Aubourg S., Vitulo N., Jubin C., Vezzi A., RA Legeai F., Hugueney P., Dasilva C., Horner D., Mica E., Jublot D., RA Poulain J., Bruyere C., Billault A., Segurens B., Gouyvenoux M., RA Ugarte E., Cattonaro F., Anthouard V., Vico V., Del Fabbro C., RA Alaux M., Di Gaspero G., Dumas V., Felice N., Paillard S., Juman I., RA Moroldo M., Scalabrin S., Canaguier A., Le Clainche I., Malacrida G., RA Durand E., Pesole G., Laucou V., Chatelet P., Merdinoglu D., RA Delledonne M., Pezzotti M., Lecharny A., Scarpelli C., Artiguenave F., RA Pe M.E., Valle G., Morgante M., Caboche M., Adam-Blondon A.-F., RA Weissenbach J., Quetier F., Wincker P.; RT "The grapevine genome sequence suggests ancestral hexaploidization in RT major angiosperm phyla."; RL Nature 449:463-467(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FN595243; CCB47784.1; -; Genomic_DNA. DR EnsemblPlants; VIT_16s0050g02160.t01; VIT_16s0050g02160.t01; VIT_16s0050g02160. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1143 AA; 129145 MW; 9AB937FB04819C47 CRC64; MPHSEAFTED DWKLVQLVLT LFRNILAIQD ISLQQKAGES ASQFLSLRDR FLELLFNENV MDLILVITQN VGGSSKYFRQ DNLLLLEIFH YIFMGQEPEL LAKAHLNCSK VDGDTKTSLN GLKSIIEEEE EKRKLLRIRK LNRSSQFCGA FTRVTMDGSK TFFKGNPTFT SHDKFLKPQV PRGPLKKIVW DHGSLPSAKD NILELVHDFV NQFLSGGYNV LMQSICEDIE KEHHAIQNSD VVVFFQVSQF VTSFQYHKFL ISKPNRGMDT SETFANEYAD STFFKGDICG PIAATMNEAM FLLVVLKWRN AFDGLKETND YKFLSAAGSL MKNMIRMLDL VLKLSLEDSK EPQTARILLY KLFYDQTDQG MTHFLLNLIK SFDSHKQPKS DLADLVEMIY IVVQLMENLQ AHGTLRVRYV FFCGLILSGE SVNLRLLKKR TLSDKNENEG EHGDHGVIQN EIGVSNCGQS VDLNMSQKES LENSISDGRQ EAVIQIEPEI PVLGTGNLGG SLPHMDVQKA KNTTDDLHYG TDDSSGDEQA AVVDEVDFKV STLVSAFANN HVIQNLCWLL KFYKSNSTTT NHYIICILRK ICDDLELSPM LYQLSLLTIF YNILCEQKSC PCKDYENIVC FLTNLVRKML RKMKSQPLLF VEVLFWKTRG ECHYITSQSL LHELGSLKKE SGKWGNISRH GEIGSTEGKG WMHRSIADAL GEDEADVVIS HEPVYQKNDD NFSEAEEGVT PISSSKIDGK TNSDNVGHYA EHESERVSKR KRRLVLSAEV EKNIKDLYEK FKDDRHCSRL IAEALDPDCK VSPVQVSNKL KQLGLKIAPK KRMLQVDVPL SDSTNQLMEE ARAVGEESAH LVCSNNSEGS LVRKSLHTRK RVRAFSKDQE ETIRALYEQF KGHKRCTYMI ASALAGDDIL TAAQVSRKLK QLGLHVPRRK RAEGNMHLRD EDLNDFDTAK AQDSDDETLL SLRKRSKKEN HRLLREEVPE QNIEGKLMQS SDDETLSSVL KKTRRLPPKL DEKRTSTSNG RLGIDDPSGS VVAKDVTKRD GHTLSDELEV AGIEDDVAFK HVSLDDNSED EIMAFSSEKQ LGAASANNRD ISPHQQVADE LADSGDDIAS SALPINSTSR RKLRMVIDFE DDE // ID F6PYQ9_MACMU Unreviewed; 1205 AA. AC F6PYQ9; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Macaca mulatta (Rhesus macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9544; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=17573; RX PubMed=17431167; DOI=10.1126/science.1139247; RA Gibbs R.A., Rogers J., Katze M.G., Bumgarner R., Weinstock G.M., RA Mardis E.R., Remington K.A., Strausberg R.L., Venter J.C., RA Wilson R.K., Batzer M.A., Bustamante C.D., Eichler E.E., Hahn M.W., RA Hardison R.C., Makova K.D., Miller W., Milosavljevic A., Palermo R.E., RA Siepel A., Sikela J.M., Attaway T., Bell S., Bernard K.E., Buhay C.J., RA Chandrabose M.N., Dao M., Davis C., Delehaunty K.D., Ding Y., RA Dinh H.H., Dugan-Rocha S., Fulton L.A., Gabisi R.A., Garner T.T., RA Godfrey J., Hawes A.C., Hernandez J., Hines S., Holder M., Hume J., RA Jhangiani S.N., Joshi V., Khan Z.M., Kirkness E.F., Cree A., RA Fowler R.G., Lee S., Lewis L.R., Li Z., Liu Y.-S., Moore S.M., RA Muzny D., Nazareth L.V., Ngo D.N., Okwuonu G.O., Pai G., Parker D., RA Paul H.A., Pfannkoch C., Pohl C.S., Rogers Y.-H.C., Ruiz S.J., RA Sabo A., Santibanez J., Schneider B.W., Smith S.M., Sodergren E., RA Svatek A.F., Utterback T.R., Vattathil S., Warren W., White C.S., RA Chinwalla A.T., Feng Y., Halpern A.L., Hillier L.W., Huang X., RA Minx P., Nelson J.O., Pepin K.H., Qin X., Sutton G.G., Venter E., RA Walenz B.P., Wallis J.W., Worley K.C., Yang S.-P., Jones S.M., RA Marra M.A., Rocchi M., Schein J.E., Baertsch R., Clarke L., Csuros M., RA Glasscock J., Harris R.A., Havlak P., Jackson A.R., Jiang H., Liu Y., RA Messina D.N., Shen Y., Song H.X.-Z., Wylie T., Zhang L., Birney E., RA Han K., Konkel M.K., Lee J., Smit A.F.A., Ullmer B., Wang H., Xing J., RA Burhans R., Cheng Z., Karro J.E., Ma J., Raney B., She X., Cox M.J., RA Demuth J.P., Dumas L.J., Han S.-G., Hopkins J., Karimpour-Fard A., RA Kim Y.H., Pollack J.R., Vinar T., Addo-Quaye C., Degenhardt J., RA Denby A., Hubisz M.J., Indap A., Kosiol C., Lahn B.T., Lawson H.A., RA Marklein A., Nielsen R., Vallender E.J., Clark A.G., Ferguson B., RA Hernandez R.D., Hirani K., Kehrer-Sawatzki H., Kolb J., Patil S., RA Pu L.-L., Ren Y., Smith D.G., Wheeler D.A., Schenck I., Ball E.V., RA Chen R., Cooper D.N., Giardine B., Hsu F., Kent W.J., Lesk A., RA Nelson D.L., O'brien W.E., Pruefer K., Stenson P.D., Wallace J.C., RA Ke H., Liu X.-M., Wang P., Xiang A.P., Yang F., Barber G.P., RA Haussler D., Karolchik D., Kern A.D., Kuhn R.M., Smith K.E., RA Zwieg A.S.; RT "Evolutionary and biomedical insights from the rhesus macaque RT genome."; RL Science 316:222-234(2007). RN [2] RP IDENTIFICATION. RC STRAIN=17573; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSMMUT00000030782; ENSMMUP00000028809; ENSMMUG00000021878. DR GeneTree; ENSGT00390000015124; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1205 AA; 138809 MW; E5828F194542389A CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASIHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGIGQG RLAQERSADV AELEVLRQRE MAEKKTRALQ RGSRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDLSPDEA VRESSRIIKN NIFYVMEYRE LFLTLFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRRKKKKVLD QATVSGNVPS SPEELEAMWP ALAEQLECCA QNPELGIDSM VPFDAASEVP VEEQRAEAMV RIQDCLLAGQ APQALTLLRS AREVWPEGDV FGSQDISPEE EIQLLKQILS APLPRQQGPE ECGTEEEEEE EEEEEEEELQ VVQVSEKEFN FLDYLKRFAC STVVRAYVLL LRSYQQNSAH TNHCIVKMLH RLAHDLKMEA LLFQLSVFCL FNRLLSDPAA GAYKELVTFA KYILGKFFAL AAVNQKAFVE LLFWKNTAVV REMTEGYGSL DDRSSSRRAP TWSPEEEARL RELYLAHKDV EGQDVVEAIL AHLNTVPRTR KQIIHHLVQL GLADSVKDFQ RKGTHIVLWT GDQELELQRL FEEFQDSDDV LGHIMKNITA KRSRARIVDK LLALGLVAER RELYKKRRKK LASSILPNGA ESLKDFCQED LEEEEKLPEE DSEEDEEGSS EAEEVQGSLV LSTENLGQSL HQEGFSTPLL WLQHCIRAAD DREEDGCSQA VPLVPLTEEN EEAMENEQFQ QLLRKLGVRP PASEQETFWR IPAKLSPTQL RRVAASLNQP EEEQKLQPEL QPEVPGEEGS DEEHCKEHRP QALRALLLTH KKKGLASPEE EDTVGKEQLK TAPKKRQLLD SDEEQEDEGR NRAPELAAPR IQKKKRFQIE DDEDD // ID F6QW70_HORSE Unreviewed; 1211 AA. AC F6QW70; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 14-MAY-2014, entry version 15. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Equus caballus (Horse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus. OX NCBI_TaxID=9796; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Thoroughbred; RX PubMed=19892987; DOI=10.1126/science.1178158; RG Broad Institute Genome Sequencing Platform; RG Broad Institute Whole Genome Assembly Team; RA Wade C.M., Giulotto E., Sigurdsson S., Zoli M., Gnerre S., Imsland F., RA Lear T.L., Adelson D.L., Bailey E., Bellone R.R., Bloecker H., RA Distl O., Edgar R.C., Garber M., Leeb T., Mauceli E., MacLeod J.N., RA Penedo M.C.T., Raison J.M., Sharpe T., Vogel J., Andersson L., RA Antczak D.F., Biagi T., Binns M.M., Chowdhary B.P., Coleman S.J., RA Della Valle G., Fryc S., Guerin G., Hasegawa T., Hill E.W., Jurka J., RA Kiialainen A., Lindgren G., Liu J., Magnani E., Mickelson J.R., RA Murray J., Nergadze S.G., Onofrio R., Pedroni S., Piras M.F., RA Raudsepp T., Rocchi M., Roeed K.H., Ryder O.A., Searle S., Skow L., RA Swinburne J.E., Syvaenen A.C., Tozaki T., Valberg S.J., Vaudin M., RA White J.R., Zody M.C., Lander E.S., Lindblad-Toh K.; RT "Genome sequence, comparative analysis, and population genetics of the RT domestic horse."; RL Science 326:865-867(2009). RN [2] RP IDENTIFICATION. RC STRAIN=Thoroughbred; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR RefSeq; XP_001504893.2; XM_001504843.3. DR PRIDE; F6QW70; -. DR Ensembl; ENSECAT00000004648; ENSECAP00000003227; ENSECAG00000002892. DR GeneID; 100059661; -. DR KEGG; ecb:100059661; -. DR CTD; 8914; -. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1211 AA; 139610 MW; CA0AE6024593787C CRC64; MDLYMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILI QHRQDQPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLSYLQAY KEAFASEKAF GVLSETLYKL LQLGWEERQE EDNLLIERIL LLIRNILHVP ADLDQEKRID DDASVHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERNTDV AELEALRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLQNYSSD LGKQPRRVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMSPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERWQPRSFLR DLVETTHLFL KMLERFSRNR GNLVVQNKRK KRKKKKKVLD QPVASANVPS SPEELEAVWP SLAEQLQCCA QDPELSLDSM VPFDAASEVP VEEQRAEAMV RIQDCLLGGQ APQALTLLRS AREVWPEGDV FGSQDISPEE EIQLLRQILC APLPRQQGPE ERGAEEEEEE EEEEEEELEM VQVSEKEFNF LDYLKRFASS TVIRAYVLLL RNYQQNSAHT NHCVVKMLHR LAHDLKMEAL LFQLSLFCLF NRLLSDPASG AYKELVTFAK YILGKFFALA AVNQKAFVEL LFWKNTAVVR EMTEGYGSLD GGSSSRRPPV WSPEEEAQLQ ELYLAHKDVE GQDVVDAILA HLNAAPRTRK HIVHHLVRLG LADSVKDFQR KGTHIVLWTE DQELELRRLF EEFQDSDDVL GHIMKNITAK RSRARIVDKL LALGLVAERR ELYKKRRKKL APSSLPDGEK SLKDFCQEDL EEEENLPEEE SEEDEEREEG SETEQAQGSS VLSTPNLGQS LHQEGFSTPL LWLQNCLIRV ADDRKEDGCS QAVPLVPLTE ENEEAMENEQ FQQLLRKLGV RPPASGQETF WRIPAKLSPT QLRRMAASLS QPEEEEKLQP GIEPEVPGEQ GAEEEHHKEH RAQALRALLL ARKKKAGLVS PEEEETPGEK EQLKVAPKKR QLLDSDEEQE EEESRSKAPE LGAPRIQKKK RFQIEDEDEN D // ID F6THE4_CIOIN Unreviewed; 1093 AA. AC F6THE4; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 2. DT 03-APR-2013, entry version 11. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis). OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; OC Phlebobranchia; Cionidae; Ciona. OX NCBI_TaxID=7719; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12481130; DOI=10.1126/science.1080049; RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., RA De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., RA Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., RA Lemaire P., Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., RA Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L., RA Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S., RA DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H., RA Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M., RA Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M., RA Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A., RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M., RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., RA Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., RA Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., RA Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S., RA Kohara Y., Levine M., Satoh N., Rokhsar D.S.; RT "The draft genome of Ciona intestinalis: insights into chordate and RT vertebrate origins."; RL Science 298:2157-2167(2002). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EAAA01000047; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; EAAA01000048; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCINT00000004143; ENSCINP00000004143; ENSCING00000002042. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1093 AA; 126269 MW; 7106AB42B40AD54B CRC64; NMNTEILSTC ASLGYLEDDK YFKEVDCLDS IKYLIKYLHN DDNNHSVRIQ LGESQILQND LIPLLIHYAN DGDLFQTVLR LVVNLTQPTL LCFGGKVPKD TLLHHHFLQI VAYNQGYKEA FGSGGEIWKI LSQKVYDVLE TEWEDRRPEV GLLVERILIL IRNLLHIPPT NEDRDKTSNF SSHDKIIREM HIAEIDSLIL YVSGSPTEQE WCLHIIEIIC LLLKEQVAET LGKTGKMKSE SERQKEGDEL LNLRRIEETK KKAVRAKMNP WHSRFGGTFV HRGTKSISDE RDLIVHKAVR QCDKVTFDDG KAKLKKARNR RALVQDDVKC RSSLNIRNTL KEFCSRLLDS SYNVLMKAVK DRLSREKAQD HDETYYFWAM SFFLQFNRWI KFSLFSLCMW YIKHFLSLRS IKNKIHFKFG VNLLLKPKSR VLMTVHTMEQ ANDTSLKEAS KVILNNIFYV VEYREIFLTL LRKFDERKQT RGFLKDVVKA THLFLKMFEN YCNCRDNTVV VEKRIRSKKK KKKAKKPIGE NNLTEEERAL KWGEVQTELR EFLQETSPAT SEILAADIFD PTSDQTEEEQ QRTTVVKIQR YIHAGRCSEA VSTLRVAREL WPEKQIFGSA TMTSDEELTS LQEVCLADLT SVAAPQDNEE SEEEESDEEV LPPPRSTEVE FNYQDYLKKF ADSRIMVQYV RLLKEFDQND EHVNHCLVKM LHRVGFTLKM YGLLFHVSLF RVFQKVNASV STKSSKELVT FARWLLSKFH EVAARNPTLF MEMLFWKQSA AEVYDVTEGY GSFSSVQGKS AKVVWTDDEV AELTELFHKY KDQDIDTVDG ILSDISNDSR SRLQVCKQLV RQGLAQSMAE LKKAKGTKSV AWREDDVNEL KILVEEFKSS SDPIGNILQM MSNKKPRATV INKVLALGLV NDRKELHKKR KTTPRNNKQA EPMHIGGRSD SEDEPSALSS DDDSEVDETG IKNNYLQFSC LVSAERCSSL IRDYCNHGDE DCVAWIQTSL KSALEDRGTN KCKTAEPVPL VPVTEEQESA LDDRHFKKLL KLLGLQPPDN EQERYWRIPG SMSPIKIEDS ILKLKPTTNK RQR // ID F6YH93_CIOIN Unreviewed; 1111 AA. AC F6YH93; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 2. DT 14-MAY-2014, entry version 18. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; OS Ciona intestinalis (Transparent sea squirt) (Ascidia intestinalis). OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; OC Phlebobranchia; Cionidae; Ciona. OX NCBI_TaxID=7719; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=12481130; DOI=10.1126/science.1080049; RA Dehal P., Satou Y., Campbell R.K., Chapman J., Degnan B., RA De Tomaso A., Davidson B., Di Gregorio A., Gelpke M., Goodstein D.M., RA Harafuji N., Hastings K.E., Ho I., Hotta K., Huang W., Kawashima T., RA Lemaire P., Martinez D., Meinertzhagen I.A., Necula S., Nonaka M., RA Putnam N., Rash S., Saiga H., Satake M., Terry A., Yamada L., RA Wang H.G., Awazu S., Azumi K., Boore J., Branno M., Chin-Bow S., RA DeSantis R., Doyle S., Francino P., Keys D.N., Haga S., Hayashi H., RA Hino K., Imai K.S., Inaba K., Kano S., Kobayashi K., Kobayashi M., RA Lee B.I., Makabe K.W., Manohar C., Matassi G., Medina M., RA Mochizuki Y., Mount S., Morishita T., Miura S., Nakayama A., RA Nishizaka S., Nomoto H., Ohta F., Oishi K., Rigoutsos I., Sano M., RA Sasaki A., Sasakura Y., Shoguchi E., Shin-i T., Spagnuolo A., RA Stainier D., Suzuki M.M., Tassy O., Takatori N., Tokuoka M., Yagi K., RA Yoshizaki F., Wada S., Zhang C., Hyatt P.D., Larimer F., Detter C., RA Doggett N., Glavina T., Hawkins T., Richardson P., Lucas S., RA Kohara Y., Levine M., Satoh N., Rokhsar D.S.; RT "The draft genome of Ciona intestinalis: insights into chordate and RT vertebrate origins."; RL Science 298:2157-2167(2002). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; EAAA01000047; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; EAAA01000048; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCINT00000008456; ENSCINP00000008456; ENSCING00000002042. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1111 AA; 128329 MW; 1B899205530B18B3 CRC64; NMNTEILSTC ASLGYLEDDK YFKEVDCLDS IKYLIKYLHN DDNNHSVRIQ LGESQILQND LIPLLIHYAN DGDLFQTVLR LVVNLTQPTL LCFGGKVPKD TLLHHHFLQI VAYNQGYKEA FGSGGEIWKI LSQKVYDVLE TEWEDRRPEV GLLVERILIL IRNLLHIPPT NEDRDKTSNF SSHDKIIREM HIAEIDSLIL YVSGSPTEQE WCLHIIEIIC LLLKEQVAET LGKTGKMKSE SERQKEGDEL LNLRRIEETK KKAVRAKMNP WHSRFGGTFV HRGTKSISDE RDLIVHKAVR QCDKVTFDDG KAKLKKARNR RALVQDDVKC RSSLNIRNTL KEFCSRLLDS SYNVLMKAVK DRLSREKAQD HDETYYFWAM SFFLQFNSLF SLCMWYIKHF LSLRSIKNKI HFKFGGSTKV SAHENFDPYF SYLHLFLRRF NILLSRVLMT VHTMEQANDT SLKEASKVIL NNIFYVVEYR EIFLTLLRKF DERKQTRGFL KDVVKATHLF LKMFENYCNC RDNTVVVEKR IRSKKKKKKA KKPIGENNLT EEERALKWGE VQTELREFLQ ETSPATSEIL AADIFDPTSD QTEEEQQRTT VVKIQRYIHA GRCSEAVSTL RVARELWPEK QIFGSATMTS DEELTSLQEV CLADLTSVAA PQDNEESEEE ESDEEVLPPP RSTEVEFNYQ DYLKKFADSR IMVQYVRLLK EFDQNDEHVN HCLVKMLHRV GFTLKMYGLL FHVSLFRVFQ KVNASVSTKS SKELVTFARW LLSKFHEVAA RNPTLFMEML FWKQSAAEVY DVTEGYGSFS SVQGKSAKVV WTDDEVAELT ELFHKYKDQD IDTVDGILSD ISNDSRSRLQ VCKQLVRQGL AQSMAELKKA KGTKSVAWRE DDVNELKILV EEFKSSSDPI GNILQMMSNK KPRATVINKV LALGLVNDRK ELHKKRKTTP RNNKQAEPMH IGGRSDSEDE PSALSSDDDS EVDETGIKNN YLQFSCLVSA ERCSSLIRDY CNHGDEDCVA WIQTSLKSAL EDRGTNKCKT AEPVPLVPVT EEQESALDDR HFKKLLKLLG LQPPDNEQER YWRIPGSMSP IKIEDSILKL KPTTNKRQRM P // ID F6Z6K7_XENTR Unreviewed; 1204 AA. AC F6Z6K7; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Uncharacterized protein; GN Name=timeless; OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; OC Silurana. OX NCBI_TaxID=8364; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=20431018; DOI=10.1126/science.1183670; RA Hellsten U., Harland R.M., Gilchrist M.J., Hendrix D., Jurka J., RA Kapitonov V., Ovcharenko I., Putnam N.H., Shu S., Taher L., RA Blitz I.L., Blumberg B., Dichmann D.S., Dubchak I., Amaya E., RA Detter J.C., Fletcher R., Gerhard D.S., Goodstein D., Graves T., RA Grigoriev I.V., Grimwood J., Kawashima T., Lindquist E., Lucas S.M., RA Mead P.E., Mitros T., Ogino H., Ohta Y., Poliakov A.V., Pollet N., RA Robert J., Salamov A., Sater A.K., Schmutz J., Terry A., Vize P.D., RA Warren W.C., Wells D., Wills A., Wilson R.K., Zimmerman L.B., RA Zorn A.M., Grainger R., Grammer T., Khokha M.K., Richardson P.M., RA Rokhsar D.S.; RT "The genome of the Western clawed frog Xenopus tropicalis."; RL Science 328:633-636(2010). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAMC01034891; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAMC01034892; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAMC01034893; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSXETT00000047184; ENSXETP00000047184; ENSXETG00000021816. DR Xenbase; XB-GENE-985242; timeless. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1204 AA; 139720 MW; 87B4DD732972E3E4 CRC64; MDLYMMNCEL LATCSALGYL ESDTYHKEPD CLESVKDLIR YLRHEDDTRD IRQQLGAAQI LQNDLIPLVI QHHNDKQLFD AVIRLMVNVT QPALLCFGKV PQDPTFRHHF LQVVSYLQAY KEAFANERLF GVLSEKLYDL LQMEWEQREE EHNLLIERIL LLVRNILHVP PDPEEEKSVD DDASIHDRVL WAIHMSGMDD LIKFLASSET EQQWSMHVLE TVSLMFRDQI AEHLAATGQA RSTAERDTDI KNLEILRQRE SAEKKNRALQ RGTRHSRFGG SYIVQGLKSI GDKDVIYHKG IHNFKNYTHD LGKEVRRVPK RKQQAKETEA RRRSALNVRL FLKEFCIDFL ENCYNRLMYI VKDNLIREKA QQHDETYYLW SMAFFMGFNR LFRFQPELVS ETVSIRTFHF IEQNLTNYYE MMLTDKKEAT SWARRMHLAL KAYQELLSTV HEMDHSKEEA VRESSKIIKN NIFYLMEYRE LFLALFRKFD ETKQPRSFLK DLVETTHLFL KMLEKFCKGK QTVVVQKRRV KRKKKKSSVS GAKEVQPKST EELAAIWTNV SEQLTTCIVN SENLPDSVVP FDAASEIPVE EQRAEALVRI QDGLFSGCAA EALVLLRSAR EVWPEGDVFG AAEIEPEEET ELLKQILFAE LPRSTQAESE VLGEEEEEDE IEEEELTSVQ VSEREFNFLD YMKRFANSNV VKTYVLLLKN YQQNSAHTNH CVAKMLHRIA YDLKMEALLF QLSVFCIFNK ILGDPAASAY KELVAFSKYI LNKFFSLAAT NNKAYVELLF WKNTNVIREM TEGYRKLGEE ESEANRKRIK WTPEDEDELR RLYLQFKEIE DADVVDNIVA NLKPGTRTRK QVINHLVQMG LADSVKDFKQ ETKGTRIVLW TEDQELELQR LYEDFKDSDD ILGNIMKNVT AKRSKARIIE KLISMGLVCD RKELYKKRRK KVAPLPQHKH PLSPCNPPVS LGEEESEYMP EDLNYKQIAK EQTGGRMDPF TDKNIKHLVH KLQQEGLSGP LLWLQNCLNR TAEDREEDGS SQAIPLVPLT EDNEDAMENK TFKKLLKKLG IRAPANEQES FWRIPGKLSP EQLRKAASCL VPLAAAVACE VLANAEEQEV NVEQRAEALR ALLLARKKKS SEAQQAQSKQ NFNRPKTAKK RSKMVDSDEE MLEVDQKGSF SESDTEENVQ PTKKKRLVIE DEDE // ID F7DT20_ORNAN Unreviewed; 1141 AA. AC F7DT20; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 14-MAY-2014, entry version 15. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Ornithorhynchus anatinus (Duckbill platypus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus. OX NCBI_TaxID=9258; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Glennie; RX PubMed=18464734; DOI=10.1038/nature06936; RA Warren W.C., Hillier L.W., Marshall Graves J.A., Birney E., RA Ponting C.P., Grutzner F., Belov K., Miller W., Clarke L., RA Chinwalla A.T., Yang S.P., Heger A., Locke D.P., Miethke P., RA Waters P.D., Veyrunes F., Fulton L., Fulton B., Graves T., Wallis J., RA Puente X.S., Lopez-Otin C., Ordonez G.R., Eichler E.E., Chen L., RA Cheng Z., Deakin J.E., Alsop A., Thompson K., Kirby P., RA Papenfuss A.T., Wakefield M.J., Olender T., Lancet D., Huttley G.A., RA Smit A.F., Pask A., Temple-Smith P., Batzer M.A., Walker J.A., RA Konkel M.K., Harris R.S., Whittington C.M., Wong E.S., Gemmell N.J., RA Buschiazzo E., Vargas Jentzsch I.M., Merkel A., Schmitz J., Zemann A., RA Churakov G., Kriegs J.O., Brosius J., Murchison E.P., RA Sachidanandam R., Smith C., Hannon G.J., Tsend-Ayush E., McMillan D., RA Attenborough R., Rens W., Ferguson-Smith M., Lefevre C.M., Sharp J.A., RA Nicholas K.R., Ray D.A., Kube M., Reinhardt R., Pringle T.H., RA Taylor J., Jones R.C., Nixon B., Dacheux J.L., Niwa H., Sekita Y., RA Huang X., Stark A., Kheradpour P., Kellis M., Flicek P., Chen Y., RA Webber C., Hardison R., Nelson J., Hallsworth-Pepin K., Delehaunty K., RA Markovic C., Minx P., Feng Y., Kremitzki C., Mitreva M., Glasscock J., RA Wylie T., Wohldmann P., Thiru P., Nhan M.N., Pohl C.S., Smith S.M., RA Hou S., Nefedov M., de Jong P.J., Renfree M.B., Mardis E.R., RA Wilson R.K.; RT "Genome analysis of the platypus reveals unique signatures of RT evolution."; RL Nature 453:175-183(2008). RN [2] RP IDENTIFICATION. RC STRAIN=Glennie; RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSOANT00000019824; ENSOANP00000019821; ENSOANG00000012531. DR GeneTree; ENSGT00390000015124; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1141 AA; 130422 MW; E56247E8D53BC8E3 CRC64; TASSAMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQGDLLPLLT QHRQDKPLFD AVVRLMVNLT QPALLCFGKV PQDPNLGHHF LQVLTYLRAY KEAFANEKVF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNLLHIP ADPDHEKPID DAASTHDRLL WSLHLSGLDD LLLFLASSQA EQQWSLHVLE IIALLFRDQN PEQLAAGGQA RSAQARGVDV RELEALRQRE VAERKSRALR RGSRHSRFGG SYVVQGLRAI GDQDVVFHKG LHNFQNYSPD MVKEVRRVPR RRQAAQETAA PRRSARNVRL FLGHFCTEFL ENSYNRLMAL VKDHLLRERA QQHDETYYLW ALAFFMAFNR ASHFRPGLVS ETLSIRTFHF IEQNLTNYYE MMLTDRKEAV SWGRRMHLAL KAYQELLATV HQMDQSEDEA VRESSRIIKN NIFYVLEFRE LFLALFRKFD ETRQPRSFLC DLVETTHLFL KMLEHFCRGR GGLMVQNKKR RKKRKKAPAR PRPSPAGTLP LSPEQQEELW TTLAEQLRLC AQDPVLPADD VVPFDAASEV PVEEQRTEAM VRIQESLLGG QAAGALSLLR AAREVWPEGD VFGAPELSAE EEVQLLRQIL SASLPRKGAG EEEEEGEEEE EEAEVEEEAE EELQAVQVSE KEFNFLDYLK RFASSTVVRA YALLLRNYRL NSPHTNHCVV KMLHRLARDL KMDALLFQLS LFCLFHRLLS DPAAPAYPEL VTFAKYILGR FFTLAASNSK AFVELLFWKN TSAVREMTEG YGTLGGDGSS TVLSAWERED VVDAILARLG PARRTRKQII HHLVRLGLAD SVKDFQKPRQ LALGTQLVLW TEEQELELQR LFEEFRDSDD VLGGIMKNLT AKRGRARVVD KLLSLGLVAE RRELYKKRSR RKARADGKEA LRTSCQRREE KEEAEEEEEE EEESEEEEEE EPEGEEESGA ERGQHDPSGL EHNLWQQGFS GPLQWLQNCL IRVATDREED GCSQAVPLVP LTEENEEAME DRRFQRLLRR VGARPPASEQ ESFWRIPAKL SPRQLRRMAA SLGQPREDGA PGPEPDGPGQ GEAGGAPDGG PPHEEQPTQA LQALLQTRKR R // ID F7F5T6_CALJA Unreviewed; 707 AA. AC F7F5T6; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 16-MAY-2012, entry version 5. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Callithrix jacchus (White-tufted-ear marmoset). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Platyrrhini; Cebidae; Callitrichinae; Callithrix. OX NCBI_TaxID=9483; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.; RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACFV01143071; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ACFV01143072; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCJAT00000021556; ENSCJAP00000020402; ENSCJAG00000010984. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 707 AA; 80548 MW; 1B5E0949313917B3 CRC64; IDLSMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASVHDQLL WAIHLSGLDD LLLFLASSSS EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSTDI AELGALRQRE MAEKKTRALQ RGNRHSRFGG SFIVQGLKSI GERDVIFHKG LHNLRNYSSD LGKQPQKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL NTVPRTRKQI IHHLVQLGLA DSVKDFQRKG THIVLWTEDQ ELELQRLFEE FQDSDDVLGH IMKNITAKRS RARIVDKLLA LGLVAERREL YKKRRKKLAS SSLPKGAESL KDFCQEDLEE EENLPEEESE EEGEGGSEAE QVQGSSVLST ENLGQSLHQE GFSTPLLWLQ NCLIRAADDR EEDGCSQAVP LVPLTEENEE AMENEQFQQL LRKLGVQPPA SGQETFWRIP AKLSPTQLRR VAASLSQPEE EQKLQPELQP EVPGEQDSDE EHHKEHRAQA LRALLLARKK KAGLASPEEE DTVVGKEPLK AAPKKRQLLD SDEEQEEDEG SNRAVPELGA PGIQKKKRFQ IEDDEDD // ID F7FXN9_CALJA Unreviewed; 1213 AA. AC F7FXN9; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Callithrix jacchus (White-tufted-ear marmoset). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Platyrrhini; Cebidae; Callitrichinae; Callithrix. OX NCBI_TaxID=9483; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.; RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUN-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACFV01143071; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ACFV01143072; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCJAT00000021549; ENSCJAP00000020395; ENSCJAG00000010984. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1213 AA; 139055 MW; 2C58B93B048CBE7A CRC64; IDLSMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASVHDQLL WAIHLSGLDD LLLFLASSSS EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSTDI AELGALRQRE MAEKKTRALQ RGNRHSRFGG SFIVQGLKSI GERDVIFHKG LHNLRNYSSD LGKQPQKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFQPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMSPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFN ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKQK KRKKKKKKKK VLDQAIVSGS ISSSPEELVA VWPALAEQLQ CYTQNPELSA DSVVPFDAAS EVPVEEQRAE AMVRIQDCLL AGQAPQALTL LRSAREVWPE GDVFGSQDIS PEEEIELLKQ ILSAPLPRQQ GPEERGAEEE EEEEEEEDEE ELQVVQVSEK EFNFLDYLKR FACSTVIRAY VLLLRSYPQN SAHTNHCIVK MLHRLAHDLK MEALLFQLSV FCLFNHLLSD PAAGAYKELV TFAKYILAKF FALAAVNQKA FVELLFWKNT AVVREMTEGY GSVDDRSSSR RAPVWSPEEE AHLRELYLAH KDVEGQDVVE VILVHLNTVP RTRKQIIHHL VQLGLADSVK DFQRKGTHIV LWTEDQELEL QRLFEEFQDS DDVLGHIMKN ITAKRSRARI VDKLLALGLV AERRELYKKR RKKLASSSLP KGAESLKDFC QEDLEEEENL PEEESEEEGE GGSEAEQVQG SSVLSTENLG QSLHQEGFST PLLWLQNCLI RAADDREEDG CSQAVPLVPL TEENEEAMEN EQFQQLLRKL GVQPPASGQE TFWRIPAKLS PTQLRRVAAS LSQPEEEQKL QPELQPEVPG EQDSDEEHHK EHRAQALRAL LLARKKKAGL ASPEEEDTVV GKEPLKAAPK KRQLLDSDEE QEEDEGSNRA VPELGAPGIQ KKKRFQIEDD EDD // ID F7GAD0_CALJA Unreviewed; 1198 AA. AC F7GAD0; DT 27-JUL-2011, integrated into UniProtKB/TrEMBL. DT 27-JUL-2011, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Callithrix jacchus (White-tufted-ear marmoset). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Platyrrhini; Cebidae; Callitrichinae; Callithrix. OX NCBI_TaxID=9483; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Warren W., Ye L., Minx P., Worley K., Gibbs R., Wilson R.K.; RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JUL-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACFV01143071; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ACFV01143072; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCJAT00000021529; ENSCJAP00000020378; ENSCJAG00000010984. DR GeneTree; ENSGT00390000015124; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1198 AA; 136944 MW; FD9A41BF34D54F08 CRC64; IDLSMMNCEL LATCSALGYL EGDTYHKEPD CLVSEESVKD LIRYLRHEDE TRDVRQQLGA AQILQSDLLP ILTQHRQDKP LFDAVIRLMV NLTQPALLCF GSLPKEPSFR HHFLQVLTYL QAYKVAFASE KAFGVLSETL YELLQLGWEE RQEEDNLLIE RILLLVRNIL HVPADLDQEK KIDDDASVHD QLLWAIHLSG LDDLLLFLAS SSSEQQWSLH VLEIVSLMFR DQNPEQLAGV GQGRLAQERS TDIAELGALR QREMAEKKTR ALQRGNRHSR FGGSFIVQGL KSIGERDVIF HKGLHNLRNY SSDLGKQPQK VPKRRQAARE LSIQRRSALN VRLFLRDFCS EFLENCYNRL MGSVKQARHR GLAQQHDETY YMWALAFFMA FNRAASFQPG LVSETLSVRT FHFIEQNLTN YYEMMLTDRK EAASWARRMH LALKAYQELL ATVNEMDMSP DEAVRESSRI IKNNIFYVME YRELFLALFR KFNERCQPRS FLRDLVETTH LFLKMLERFC RSRGNLVVQN RSTFRRTKSE AVLDQAIVSG SISSSPEELV AVWPALAEQL QCYTQNPELS ADSVVPFDAA SEVPVEEQRA EAMVRIQDCL LAGQAPQALT LLRSAREVWP EGDVFGSQDI SPEEEIELLK QILSAPLPRQ QGPEERGVQV VQVSEKEFNF LDYLKRFACS TVIRAYVLLL RSYPQNSAHT NHCIVKMLHR LAHDLKMEAL LFQLSVFCLF NHLLSDPAAG AYKELVTFAK YILAKFFALA AVNQKAFVEL LFWKNTAVVR EMTEGYGSVD DRSSSRRAPV WSPEEEAHLR ELYLAHKDVE GQDVVEVILV HLNTVPRTRK QIIHHLVQLG LADSVKDFQR KGTHIVLWTE DQELELQRLF EEFQDSDDVL GHIMKNITAK RSRARIVDKL LALGLVAERR ELYKKRRKKL ASSSLPKGAE SLKDFCQEDL EEEENLPEEE SEEEGEGGSE AEQVQGSSVL STENLGQSLH QEGFSTPLLW LQNCLIRAAD DREEDGCSQA VPLVPLTEEN EEAMENEQFQ QLLRKLGVQP PASGQETFWR IPAKLSPTQL RRVAASLSQP EEEQKLQPEL QPEVPGEQDS DEEHHKEHRA QALRALLLAR KKKAGLASPE EEDTVVGKEP LKAAPKKRQL LDSDEEQEED EGSNRVPELG APGIQKKKRF QIEDDEDD // ID F7W6Y5_SORMK Unreviewed; 1235 AA. AC F7W6Y5; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 14-MAY-2014, entry version 10. DE SubName: Full=WGS project CABT00000000 data, contig 2.36; GN ORFNames=SMAC_07054; OS Sordaria macrospora (strain ATCC MYA-333 / DSM 997 / K(L3346) / OS K-hell). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; OC Sordaria. OX NCBI_TaxID=771870; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-333 / DSM 997 / K(L3346) / K-hell; TISSUE=Mycelium; RX PubMed=20386741; DOI=10.1371/journal.pgen.1000891; RA Nowrousian M., Stajich J., Chu M., Engh I., Espagne E., Halliday K., RA Kamerewerd J., Kempken F., Knab B., Kuo H.C., Osiewacz H.D., RA Poeggeler S., Read N., Seiler S., Smith K., Zickler D., Kueck U., RA Freitag M.; RT "De novo assembly of a 40 Mb eukaryotic genome from short sequence RT reads: Sordaria macrospora, a model organism for fungal RT morphogenesis."; RL PLoS Genet. 6:E1000891-E1000891(2010). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CABT02000036; CCC13275.1; -; Genomic_DNA. DR RefSeq; XP_003349701.1; XM_003349653.1. DR GeneID; 10807217; -. DR KEGG; smp:SMAC_07054; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SUPFAM; SSF48371; SSF48371; 5. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1235 AA; 140425 MW; 3146AD3EF90C972A CRC64; MEAADINDDV VHPEVRAHIT NLVSALGGYS VDEDGSYKLG DEALDVLRDL KKWIRFYDEK TNRMDVARCL AEANLVGGDL LQILTLWPQN ETDSKYKARI ALACFEVMVP LTWPIEKERA EMTINHHRHM PVLQLAQLGY KRAIINFDAI PILNTAVRVA LPSMAMPIGE RTPRDLAIIK LILFFLRNVA MIAPPQGVKY EGDETQVSRS ATIDAFSYQD IFLTLLTLAS NMGEDFRTED VIVMEIIFHL VKRVDPSSLF VSEKQLNKAK GQELASEMRK ETAMLKSYNK TTTTRHSRFG TMIWVKRADG KMVTVSGQEA LLDAKTRERK MDSSKTFRPP RRARKPEREP KDLGPPVTLD ERARQQLRSF VQDFLDSGFN PLFLHVRQSI DREALHVLNQ HKSQFFYLVA WFLEAERMRR KAKREESKST SAAGEEVNSF NLVAAVLQQE MFASMNRALD RSYSDKDWQL LTSVMRCYTQ IFLTVQEMSE SPNEEDQEIA ENTLSRLFYE ETTHDLIANI ARTYKDQGFE YLDAATELVH TFLRMLEGYS KQNVDLQVRS RKRARRKKKA AKAAAAAATT APGEEAEDVG VPEENDADDS GDDEQHAERV TQERKFEFGK FAIRFAPQGV VDTFVALTKF YRDLNDTQLK RAHRYFYRVA FKQELGVMLF RLDIINLFYN MVKGPEPLDK NSPMFKEWEE LSKQIIRKCV KKLQERPALF TELLFSKIGS TTHFLEHGYE KPVTTTTPRP GAELEFKRAT ERDEQIGIAV SVLIDKQQTE HLQWLKDQLT SAMNERQAWE NVDKAMAATT EGAADGEAGE DSMNKSAPPH VTIRPDTEAR RTAMFKNPHL RLLMRLVGME RLTPTLDETP DSTWILPGNH TAEAIQDTID LINKAEFSPP TFEDGGSAED QLRRKSAAAS RRTRAAYDDD EEEIRGFLGD DDDEGGIGED FLFAPGGPTA RKPDARPQKK RQRRRRREAG SGDEEDEGVS DEVLAARAKK RREKELEKMR KIKSEMYVHA SDDETDDERD REFFEREKKR QEAKDSTFDS MLGTLGLSVL SQVNGGEKSA WEAVLDDEDG SDGSEGEGGR SAKRRKKQVA SDSEEEEEEE EDSDEELPTK PVKASKTKKK AAPKRPVRRS AALKKKAVVE LSDDEEEEEE EEDEEEDAMD VDSDNERTTT KDAPPPSSPG DGLGRRINKM VMDDNDEDED DQPVVAARQR PRARGGFVID SSDEE // ID F8MCY2_NEUT8 Unreviewed; 1235 AA. AC F8MCY2; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 22-JAN-2014, entry version 8. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=NEUTE1DRAFT_119688; OS Neurospora tetrasperma (strain FGSC 2508 / ATCC MYA-4615 / P0657). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; OC Neurospora. OX NCBI_TaxID=510951; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FGSC 2508 / P0657; RX PubMed=21750257; DOI=10.1534/genetics.111.130690; RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A., RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., RA Taylor J.W.; RT "Massive changes in genome architecture accompany the transition to RT self-fertility in the filamentous fungus Neurospora tetrasperma."; RL Genetics 189:55-69(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL891302; EGO60526.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SUPFAM; SSF48371; SSF48371; 4. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1235 AA; 140584 MW; F71C68DE9FFFE60E CRC64; MEAADIIDDV VHPEVRAHIT NLVSALGGYS VDDDGSYKLG DEALDVLRDL KKWIRFYDEK TNRMDVARCL AEANLVGGDL LQILTLWPQS ETDSKYKARI ALACFEVMVP LTWPIEKERA EMTINHHRHM PVLQLAQLGY KRAIINFDAI PILNTAVRVA LPSMAMPIGE RTPRDQAIIK LVLFFLRNVA MIAPPQGVKC EGDETQVSRS ATIDAFSYQD IFLTLLTLAS NMGEDFRTED VVVMEIIFHL VKRVDPSSLF VSEKQLNKAK GQELASEMRK EAAMLKSYNK TTTTRHSRFG TMIWVKRADG KMVTVSGQEA LLDAKTRERK MDNSKTFRPP RRARKPEMEP KDLGPPVTLD ERARQQLRSF VQDFLDSGFN PLFLHVRQSI DREALHVLNQ HKSQFFYLVA WFLEAERMRR KAKRDESKST SAAGEEVNSF NLVAAVLQQE MFASMNRALD RSYSDKDWQL LTSVMRCCTQ IFLTVQEMSE SPNEEDQEIA ENTLSRLFYE ETTHDLIANI ARTYKDQGFE YLDAATELVH TFLRILEGYS KQNVDLQVRS RKRARRKKKA AKAAAAVAAA RAAGEEAEDV GVPEDNDADD SGDDEQHAER VTQERKFEFG KFAIRFAPQG VVDTFVAFTK FYRDLNDAQL KRAHRYFYRV AFKLELSIML FRLDIINLFY NMVQGPEPLD KSSPMFKEWE ELSKQIIRKC IKKLQERPAL FTELLFSKIG STTHFLEHGY EKPVTTTMPR PGAELEFKRA TERDEQIGIA VSVLIDKQQV EHLQWLKDQL TSAMSERQAW ENVDKAMAAT TEGAADGEAA DERSNKSAPP HITIRPDTEA RRTAMFKNPH LRLLMRLVGM ERLTPTLDET PDSTWILPGS HTAEAIQDTI DLINKAEFSP PTFEDGGSAE DQLRRKSAAA SRRTRAAYDD DEEEIRGFLG DDDEEDFLFA PGGPTARKPD ARPQKKRQRK RRREAGSGDE EDEGVSDEVL AARVKKRREK ELEKIRRIKS EMYVHASDDE TDDERDREFF ERERKRQETK DSKFDSLLGA LGLSVLSQVN GGEKSAWEAV LDDEPESDES ENEGRKNAKR RKKQVASGSE EEQEEEEEEE EEEDSDEELP TKQAKSKTSK RKAAALSKRP ARRPGTTKKR AVVELSDDDE DDDEEEDAMD VDSANERTTR NEAPLPSSPG EGLGRRINKM AMDDGDEDED DQPVVAARQR PKARGGFIID SSDEE // ID F8NS69_SERL9 Unreviewed; 1338 AA. AC F8NS69; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 09-JUL-2014, entry version 10. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SERLADRAFT_436724; OS Serpula lacrymans var. lacrymans (strain S7.9) (Dry rot fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Boletales; Coniophorineae; OC Serpulaceae; Serpula. OX NCBI_TaxID=578457; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=S7.9; RX PubMed=21764756; DOI=10.1126/science.1205411; RA Eastwood D.C., Floudas D., Binder M., Majcherczyk A., Schneider P., RA Aerts A., Asiegbu F.O., Baker S.E., Barry K., Bendiksby M., RA Blumentritt M., Coutinho P.M., Cullen D., de Vries R.P., Gathman A., RA Goodell B., Henrissat B., Ihrmark K., Kauserud H., Kohler A., RA LaButti K., Lapidus A., Lavin J.L., Lee Y.-H., Lindquist E., Lilly W., RA Lucas S., Morin E., Murat C., Oguiza J.A., Park J., Pisabarro A.G., RA Riley R., Rosling A., Salamov A., Schmidt O., Schmutz J., Skrede I., RA Stenlid J., Wiebenga A., Xie X., Kuees U., Hibbett D.S., RA Hoffmeister D., Hoegberg N., Martin F., Grigoriev I.V., RA Watkinson S.C.; RT "The plant cell wall-decomposing machinery underlies the functional RT diversity of forest fungi."; RL Science 333:762-765(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL945432; EGO26900.1; -; Genomic_DNA. DR RefSeq; XP_007317073.1; XM_007317011.1. DR GeneID; 18814736; -. DR OrthoDB; EOG7PGF01; -. DR Gene3D; 1.10.3560.10; -; 1. DR InterPro; IPR021148; Put_polysacc_synth. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR InterPro; IPR023139; Yst0336-like_domain. DR Pfam; PF04669; Polysacc_synt_4; 1. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1338 AA; 152391 MW; 3730262AFD7D1CF1 CRC64; MATNFDPNNA QNLIEIEKQF AVKAVEHAQT YWNLLEKIPP ADMKLTKLDD EIYDHLMKTF PEFADPPHDK LVRLDEDWLK SDDGKKKWRD FIQAYENKVK DYNFGSLIRT DARLEYGETN TIFVTRIQFL AIEIARNKMG LNDGAHEVAK ADVEKERLKK EKEKSKGAKK NASLTSIMDT EVISLHSEDS DKEGDVDRRA ILEPVIRRVV DALGGYEGGV YRLGDELGGC LRDLKKLWRK DDTDDERTVA RIFWETRVLP NDLVPILLAT AGQGLVEDKG AIACADLMTA MIWPIDMAEE LKELDENLDK GTDYTQLLFS HLTYKAALLK PGVMAALFGI LLPPLSKPPR ERKERDGQIV NVILHLFRNL AFIKDPPPNM HLSVDQAEFS SLQTKLIKSF SESHILDLLL TVASDASNDL LFNGANTLVL EIFYLLFRGV KPSLLAIDQA KQPAQNLHRL LAAEGRIKRD HARNSSSRHS RFGTTIAVRL NPNKQGKRKE NTNDGNEADS EAPASNGSSQ SFVLHRQQAI SREAGSIMDM TKRQKARNVN KVDELTREDN LSMEAKATLR NLAREFIESC FNPFLSSLLK DIKSERPKIT EKDNLRLLYV TKWFLEFFLV TRTNQHTTSD DSRKWGLGLI AEVTDGGWIT WVLKRMREAM DEKPKMWTEL QAGIECLTQL LLLIDNMTAS TNSDTELDDA ADILQQQLIY NGEVLDVALE SLRSYKEGTQ TLTYLDSSIH LSHALIRMLE CWGKQRGEMY VRKKKASRNT RAKGKGLTEE DGIPDVEDLE DAEDAENVIH ETMFTFEAFE MKFANAEITH TLLTYLARYK EYESSEQMKR VVSLIHRQAV KAKAEGLFFN ASTFILFKSI LDEQRSLPRE QAYKDLVNLI NFILRQFFKA MAEQPFLAVE AFFPKNRGHW KQYSSWEPDQ KSKKGRETIE DTAFPPEVQV KKGYSWSEQI GIAVASLVEE GKIELVEWVK DILTLVVRQR ERVVEETDDK EGAADGQDLD DFEETTKLIG PSDEAISKFT DYVIPYINDE HANAATKNSR IKLVFRLLNF SILSEDADEL EWFVPAALLP SDLQRSFNVI EQYLKDPIDL NGKNASQMLS SKRRRRRRQR SLSPDTDVEF LDDEPKRRKK ERQKKEKEQY KSAQFIEDSD EEYGDMDTFL EKEKVLREKA AKTAAETGKI ATMKATGTKK RRRNGKDIGG GKKKWRGDEE VLNSDVEGAD SDPSSENDDI LASPHLQSVA APDTVQELIP KPRPKPRPTR RSLKPLPEGQ PDQSDHSNLI DHSETIDLSK HRSHSPDTAE SDDLMTATAV RETRRKGRIV ISDDDEGS // ID F8PS75_SERL3 Unreviewed; 1163 AA. AC F8PS75; DT 21-SEP-2011, integrated into UniProtKB/TrEMBL. DT 21-SEP-2011, sequence version 1. DT 13-NOV-2013, entry version 4. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SERLA73DRAFT_51065; OS Serpula lacrymans var. lacrymans (strain S7.3) (Dry rot fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Agaricomycetidae; Boletales; Coniophorineae; OC Serpulaceae; Serpula. OX NCBI_TaxID=936435; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=strain S7.3; RX PubMed=21764756; DOI=10.1126/science.1205411; RA Eastwood D.C., Floudas D., Binder M., Majcherczyk A., Schneider P., RA Aerts A., Asiegbu F.O., Baker S.E., Barry K., Bendiksby M., RA Blumentritt M., Coutinho P.M., Cullen D., de Vries R.P., Gathman A., RA Goodell B., Henrissat B., Ihrmark K., Kauserud H., Kohler A., RA LaButti K., Lapidus A., Lavin J.L., Lee Y.-H., Lindquist E., Lilly W., RA Lucas S., Morin E., Murat C., Oguiza J.A., Park J., Pisabarro A.G., RA Riley R., Rosling A., Salamov A., Schmidt O., Schmutz J., Skrede I., RA Stenlid J., Wiebenga A., Xie X., Kuees U., Hibbett D.S., RA Hoffmeister D., Hoegberg N., Martin F., Grigoriev I.V., RA Watkinson S.C.; RT "The plant cell wall-decomposing machinery underlies the functional RT diversity of forest fungi."; RL Science 333:762-765(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL945478; EGO01257.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1163 AA; 132002 MW; BA67894FEC484A7A CRC64; MDTEVISLHS EDSDKEGDVD RRAILEPVIR RVVDALGGYE GGVYRLGDEL GGCLRDLKKL WRKDDTDDER TVARIFWETR VLPNDLVPIL LATAGQGLVE DKGAIACADL MTAMIWPIDM AEELKELDEN LDKGTDYTQL LFSHLTYKAA LLKPGVMAAL FGILLPPLSK PPRERKERDG QIVNVILHLF RNLAFIKDPP PNMHLSVDQA EFSSLQTKLI KSFSESHILD LLLTVASDAS NDLLFNGANT LVLEIFYLLF RGVKPSLLAI DQAKQPAQNL HRLLAAEGRI KRDHARNSSS RHSRFGTTIA APASNGSSQS FVLHRQQAIS REAGSIMDMT KRQKARNVNK VDELTREDNL SMEAKATLRN LAREFIESCF NPFLSSLLKD IKSERPKITE KDNLRLLYVT KWFLEFFLVT RTNQHTTSDD SRKWGLGLIA EVTDGGWITW VLKRMREAMD EKPKMWTELQ AGIECLTQLL LLIDNMTAST NSDTELDDAA DILQQQLIYN GEVLDVALES LRSYKEGTQT LTYLDSSIHL SHALIRMLEC WGKQRGEMYV RKKKASRNTR AKGMSLLRLT PTDVVGKGLT EEDGIPDVED LEDAEDAENV IHETMFTFEA FEMKFANAEI THTLLTYLAR YKEYESSEQM KRVVSLIHRQ AVKAKAEGLF FNASTFILFK SILDEQRSLP REQAYKDLVN LINFILRQFF KAMAEQPFLA VEAFFPKNRG HWKQYSSWEP DQKSKKGRET IEDTAFPPEV QVKKGYSWSE QIGIAVASLV EEGKIELVEW VKDILTLVVR QRERVVEETD DKEGAADGQD LDDFEETTKL IGPSDEAISK FTDYVIPYIN DEHANAATKN SRIKLVFRLL NFSILSEGNC SCRLLQIYAI DADELEWFVP AALLPSDLQR SFNVIEQYLK DPIDLNGKNA SQMLSSKRRR RRRQRSLSPD TDVEFLDDEP KRRKKERQKK EKEQYKSAQF IEDSDEEYGD MDTFLEKEKV LREKAAKTAA ETGKIATMKA TGTKKRRRNG KDIGGGKKKW RGDEEVLNSD VEGADSDPSS ENDDILASPH LQSVAAPDTV QELIPKPRPK PRPTRRSLKP LPEGQPDQSD HSNLIDHSET IDLSKHRSHS PDTAESDDLM TATAVRETRR KGRIVISDDD EGS // ID F9FTD8_FUSOF Unreviewed; 1144 AA. AC F9FTD8; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-MAY-2014, entry version 10. DE SubName: Full=Uncharacterized protein; GN ORFNames=FOXB_09660; OS Fusarium oxysporum (strain Fo5176) (Fusarium vascular wilt). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae; OC Fusarium; Fusarium oxysporum species complex. OX NCBI_TaxID=660025; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Fo5176; RX PubMed=21942452; DOI=10.1094/MPMI-08-11-0212; RA Thatcher L.F., Gardiner D.M., Kazan K., Manners J.; RT "A highly conserved effector in Fusarium oxysporum is required for RT full virulence on Arabidopsis."; RL Mol. Plant Microbe Interact. 25:180-190(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AFQF01002604; EGU79801.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1144 AA; 131006 MW; 7163124745FAEA40 CRC64; MELADGSTDI VHPEVRAHIN SLVSALGGIS ADSDGGYQLG DDALEVLRDL KRWIRFYDEK TNRMDVARCI HEANLVEGDL LPILSTWPEN ATDSKFKSRM ALACFELMVP LTWPMARDRE RMTVNHHRHM PVLELAQVGY KRAVVNYDGA RVLHTAIRVA LPSMAIPIGD RTQRDQGIIK LVLFFLRNIA MIEPPPDVKY EGDESQISRS ATIDAFSYQD IFLVLLTLAS NMGEDFRAED TSVMEIIYHL VKQVDIEKLF MNEQQLSKAK AGELADMMSK ESSMLKAYNR KGPTRHNRFG TMIWVKRDDG KMSSLSGQDA LADASTRNQK MDNSKTFRPP RRARKGDKDE KDLGLPTKLN SRAYDQLRSF VEDFLDSGFN PLFQHVRKTI DREAPHVMQY HRRQFFYLVA WFLEAERMRR KARKQSSQNP SEDISSFNLV AGVLNQEMFI TLNKALHESL EMKDWHELTA VMRCFTQILL TVQEMSESGN EDNEEIAENV LSRLFYEEAT HDAIATIIRT YKDQSFNYLD AATELVHHFL RILEGYSKQN IDMQVRSRKR TRRKKKAAQD AAGIENDNDE NDGSDNDAAS AERTTKERKF DFHRFATRFT PQSVVDTFVA FTKYYRDLTD SQLKRAHRYF YRVAFKAEAS VMLFRVDIIH LFYNMIKGPA ALEKSSRVFK EWEELVKQVL RKCFKKLEQR PELLVEMLFS KGSSTAFFLE YGFERQTVTT ASKAKPAAEL VFKNTEELDR QIAIVVGAML DKNQANHVAW IKKILGDAES ERKAFMAAEE AMASVEPVQD EAEEQPTESG PKAPPIFYVR PDDKDRRNAM FKNSHMRLLM KLVGLQLLDP ASEETPESAW IIPSDVSADV LKDAIHYINQ AEFSPPTFEE GVLAEHQLKR RSAPRKKADF DDDEDGEPDD PMFGPLGPTV RRPIDEEDGP KKSPRKRRPR KELTEEERQK KLKERRRKEQ DRLMSFRSEE LVRPEDDETD SEYDEAFFAR ERETKAKAAA IRHVAERLLV PRKPTRKRGI AATESASSSE EHQDGSGDSE SGHDSDPGDD FILRAMNTTL EEENEGQPEG TLPDGSDGES RKRRRISVEK TQPDEDEEMG GVNKNGDEDE DEAPVVTRRP RVRGGFAVDS DDDE // ID F9X3P1_MYCGM Unreviewed; 1181 AA. AC F9X3P1; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 03-SEP-2014, entry version 12. DE SubName: Full=Uncharacterized protein; GN ORFNames=MYCGRDRAFT_68421; OS Mycosphaerella graminicola (strain CBS 115943 / IPO323) (Speckled leaf OS blotch fungus) (Septoria tritici). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Dothideomycetes; Dothideomycetidae; Capnodiales; Mycosphaerellaceae; OC Zymoseptoria. OX NCBI_TaxID=336722; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 115943 / IPO323; RX PubMed=21695235; DOI=10.1371/journal.pgen.1002070; RA Goodwin S.B., Ben M'barek S., Dhillon B., Wittenberg A.H.J., RA Crane C.F., Hane J.K., Foster A.J., Van der Lee T.A.J., Grimwood J., RA Aerts A., Antoniw J., Bailey A., Bluhm B., Bowler J., Bristow J., RA van der Burgt A., Canto-Canche B., Churchill A.C.L., Conde-Ferraez L., RA Cools H.J., Coutinho P.M., Csukai M., Dehal P., De Wit P., RA Donzelli B., van de Geest H.C., van Ham R.C.H.J., Hammond-Kosack K.E., RA Henrissat B., Kilian A., Kobayashi A.K., Koopmann E., Kourmpetis Y., RA Kuzniar A., Lindquist E., Lombard V., Maliepaard C., Martins N., RA Mehrabi R., Nap J.P.H., Ponomarenko A., Rudd J.J., Salamov A., RA Schmutz J., Schouten H.J., Shapiro H., Stergiopoulos I., RA Torriani S.F.F., Tu H., de Vries R.P., Waalwijk C., Ware S.B., RA Wiebenga A., Zwiers L.-H., Oliver R.P., Grigoriev I.V., Kema G.H.J.; RT "Finished genome of the fungal wheat pathogen Mycosphaerella RT graminicola reveals dispensome structure, chromosome plasticity, and RT stealth pathogenesis."; RL PLoS Genet. 7:E1002070-E1002070(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM001197; EGP90507.1; -; Genomic_DNA. DR RefSeq; XP_003855531.1; XM_003855483.1. DR EnsemblFungi; Mycgr3T68421; Mycgr3P68421; Mycgr3G68421. DR GeneID; 13403471; -. DR KEGG; ztr:MYCGRDRAFT_68421; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1181 AA; 134191 MW; BF323AEC1575EE8C CRC64; MDPFEKSTTV DPEVRAYISS LVNAVGGSST YDNSYSIGDD AAAVLKDLQR WLRLYDEKTN RLDVKRCLAE ANLVQGDLLE ILALWPEDGK ENKLKSKLAL ACLELLVPLT WPVALEDDKA TLNHHRHVPY LQLAQVGYKR AVLQYEYAKI LRIAVRVALP SMAQPRRERT KRDDGIIKLM LYFFRNVAMI TQPQHLPSQG DENEVSRSAT IEVFHDQEIF NALLTIGSGL GDDFQEQDVI ILEIMFHLLK GVDARKLFLK KEEVSTEEVN ELKMLMQKEK AMLNSYKKNA PTRHNRFGTM LWVRREDMKM STVSGQTSIT DKDSTFHQMD ASKKWNKPQY RGKLTQEFDE FSEFGMRVEL TEKARAHLRR FVEDFLDSSF NPLFASLRKA IEREHDRVQA MHHKQYFYLI SWFLSAEAAR RDQARSQSAW HADRPSQINP EDNTFAYIAA VLDQETFVLL DRQMQIAFDN KSWQDLQATL LCFTQILLTV QSMADSKDEE DQEIAENIQG RIFYEEATHD RIVQILRGYT HQGFAYLDAI TECVHVFVRM LERYSKQNVD LQIRSKRRAR KKRAQQDNLD EDGERPQDAD DANDDEQEAH RAVSERKFDF ARFSAKFLSQ PCVNTFISLT HYYRDLTPAQ MKRAHRFFYR LAFKHELTVL LFRADILQLF HKMIKGPEGL DSGMEGFRDW EQMVQQVFRR CIKWMERDTE GTGWKEASVV EMLFSKIPAT VFYLQNGYEK VVEKRAPRPP AELQVKPSVP QDQRLAVAVS IMIENAKADD VEWVKKQVGN AADERQSWED EDTARRAITS ETDAVEPIAA PSIFIIPDNE ERKLALFKDK HLRLLLTTLG FLRLGLAEDV DAAWVIPSEI SASTLIEALN QIEAAEFAPP TFENDKTASD LIRTKPTGRN SGAFGDSDSE SDADGDGGLI DDAMFPPNLK EARKAREDGE KPRKRRKRRS SGPELTEARA KAKEKKEREK NSRIKSALYV VEDDTDEEAD AEFFRLEAQR RKKTSGVIQS AVMKAAKAAQ TPATEGGGKG KKRKSAVGVK VSAKKRKTAI ESEDEDEDVA SAGALSAAAT PLELSENSPS SSEDSDAMDE DDEEPVASRR GGKTKETPST SPTPGKVSVS PKPLREVSAN TTTAALLMND DDDDDEDDMP VLKPMARRSV RAGFIIESDS E // ID G0MC22_CAEBE Unreviewed; 1383 AA. AC G0MC22; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 13-NOV-2013, entry version 8. DE SubName: Full=CBN-TIM-1 protein; GN Name=Cbn-tim-1; ORFNames=CAEBREN_00693; OS Caenorhabditis brenneri (Nematode worm). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=135651; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PB2801; RG Caenorhabditis brenneri Sequencing and Analysis Consortium; RA Wilson R.K.; RL Submitted (JUL-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL379789; EGT45591.1; -; Genomic_DNA. DR EnsemblMetazoa; CBN00693; CBN00693; CBN00693. DR OMA; ARIECGR; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1383 AA; 160381 MW; B733DBB5DA40E843 CRC64; MNVLIQGAVQ ALGYLEDGKY HREPDCYETI RDLIRYLRED GDDHTARIEC GRHNLVEHDL VPMIKCDDLS DDEFDIAIRL MVNLCQPAIA TMRGKAPADR DQWKMYWELE ENLRRAKCAF TDAHFFVAIK KRIDNYFIET DVDDRDERLR LVVERIVLLV KYVFSINQDS TEGRRTRIED SSHDRVILAF LESGIDKTLM HIANQPREKE FHITILDIFA LILKEQCPEN LSKPDDSEFS AAEKKKTEED FRKIIENHVV QQTQKRKSFS RFGGSYTIQG LKGISSNSNQ VVFKPIQNVE KHNFLDERKT KKRVARNRRP FEVDSNVHLA SSEVRNMLRD MVIRLIETCF NRLMKSAKST VFVQGHALQK SSQINYFFMV KFVLKFVRMS KELTLFERIS ECIGVEAFHE NNVQLTEYVE NAITLKGVEA KSFGLKAQYA LGAYNELVLI HRHIYENAKE ELEKKRARRA LEHIVNVEEY RELPISIIKK FSSAVLSNNF LRELILTTHH YMKLVERFVK TGALKKVTKK VKVRKNQTKK KRTEEDERSQ FDLMTSDQLE ELWEESKDRL LKILSGELQE YADMNPITLE TDRESQQKFA RLSIQRSLRS RGFPAAVGLF HASKKLWPEA FKSKSLGSSE DPENPENSEN DPQEELAELY TILKSDMKAI AREFKKATLD PYSKIDKLTS EALESFWSEA KLQIPAILES ITEEDHVNPL NWQLEVSPEA QQQFAMLAIQ RSLRFNNLKK AIGLYHASRK LWPSENIFGH EGISSEEEIA ELEGILKADL TEVAKELKIA EGVANEKMNS LEDLGIDGGA EYSGNSEDEE ETPAWKVEEI DFQFDMYVSK FANVDVLKWY VFLLNDFSKN SVELNQALVK MLHRIAFDLK LPTKLYQISL FQVFQKVNEH FTHLSKELRK SSPLFELYQF GFHLLKKFFQ KFSEMGEEMA VEVLFWKGPR ECFEIENGYG SWIKNKEAEI KVWTEEMETE LRNLYDEYKS IESSDGIDVL DFIEHNLSRA RTRKQIAKKL IEFGLDLLGA KWKNIGKSEM DAVLPVGDIL KWYEEWKTDG SEGDIVEILK KKLMESIGSE VSRKKIIKQL AHMDILYEKP KKERPLPEWD QALIEELKQL KEQYEEFDDA ENMLGVDIVR YVMKRLSEKK PTRQVERYLA SMGAKIVEQP KKPRSSQPKT SKKSKDAFLN DSSEEEPVIR EDSEDEEAEE PMIPAEKSIA KKRAIVESDD EDEVAMETES TEKSKEKSPE KPKSSPKNTL MSRIALNSKK RKFAQLESDS ESSDSDDEDK LEEIVKKKKK VVVADSDSDR DDDIYKRSYT HSLLTSGSVA GGILSREPSE EKEKTPDEEE EDPFTAKLTF KRRIVVSDNE DED // ID G0R7I1_HYPJQ Unreviewed; 1155 AA. AC G0R7I1; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 03-SEP-2014, entry version 8. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=TRIREDRAFT_53659; OS Hypocrea jecorina (strain QM6a) (Trichoderma reesei). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae; OC Trichoderma. OX NCBI_TaxID=431241; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=QM6a; RX PubMed=18454138; DOI=10.1038/nbt1403; RA Martinez D., Berka R.M., Henrissat B., Saloheimo M., Arvas M., RA Baker S.E., Chapman J., Chertkov O., Coutinho P.M., Cullen D., RA Danchin E.G., Grigoriev I.V., Harris P., Jackson M., Kubicek C.P., RA Han C.S., Ho I., Larrondo L.F., de Leon A.L., Magnuson J.K., RA Merino S., Misra M., Nelson B., Putnam N., Robbertse B., Salamov A.A., RA Schmoll M., Terry A., Thayer N., Westerholm-Parvinen A., Schoch C.L., RA Yao J., Barabote R., Nelson M.A., Detter C., Bruce D., Kuske C.R., RA Xie G., Richardson P., Rokhsar D.S., Lucas S.M., Rubin E.M., RA Dunn-Coleman N., Ward M., Brettin T.S.; RT "Genome sequencing and analysis of the biomass-degrading fungus RT Trichoderma reesei (syn. Hypocrea jecorina)."; RL Nat. Biotechnol. 26:553-560(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL985056; EGR53100.1; -; Genomic_DNA. DR RefSeq; XP_006961901.1; XM_006961839.1. DR EnsemblFungi; EGR53100; EGR53100; TRIREDRAFT_53659. DR GeneID; 18485582; -. DR KEGG; tre:TRIREDRAFT_53659; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1155 AA; 133076 MW; 905AC358A2810B61 CRC64; MELADGTTDI VHPEVRAHIS SLVAALGGAS TEDDGRYHLG DDALEVLRDI KRWIRFYDEK TNRMDVARCI HEANLIEGDL LPILATWPEN ATDSKYKSRI ALSCFEIMVP LTWPLERDKE RMTVNHHRHM PVLELAQVQY KRAIINFDEA RILHAAVRTA LPSLALPAGD RTARDQGIIK LVLFFLRNIA MIAPPPNVKY EGDETQISRS ATIDAFSYQD IFLFLLTLAS NMGEDFRTED MAVMEIIYHL IKRVDIEKLF MSEQQAHKAK ANELASLMNK ESAMHKAYAR NGPTRHNRFG TMIWVKREDG KMSSLTGQDA LSDVTARNLK MDNNKVFKPP RRTKKENKDE RDLGLPAKLN ARATSQLRSF VEEFLDSGFN PLFSHVRKTI DREASHVMQY HRRQFFYLVA WFLEAERTRQ ALKKGPNNNN KANDDVSSFS LVAGVLNQEM FITLNKAMHE AYEYKDWQEL AAVMRCFTQI LLTVQAMSES GREDDEEIAE NVLSRLFYEE STHDTIANII RTYKDQGFYY LDAATELVHH FLRILEAYSK QNADMQVRSR KRTRQKKKKE QQQQQSTEDG ALAEEQDDSA NDEEATERTS KERKFDFQRF AARFTPQGVV DTFVKFTRFY RDMTDAQLKR VHRYFYRLAF KQEMSVMLFR VDIIHLLYNM IKGPEPLDKS SSMYKDWEEL VKQILRKCVK KIEQRPELIV EMLFSKLQST AFFLEYGYDK QTASKKQAKP GAELVFKYTE ERDRQIAIVV GALLDKNEAD HITWVKSVVA EAESERRSWA AAEEVLRSTE TPMEESTEAN EPKEPSKPSP IIVKPDSDAR RTARFKNSYL RLLLNLCGCQ LFGPASEETP ESLWVFPEDV TADSLKDALH FINQAEFNPP TFDDGQLAEN QLKRKTQPRK KADFDDDDVG DDLDDEFLFA PGGPTARKAV DERPKKPRKR RRRNSQAQEL DDEELEEKAR KRREREREKA RKIKSAVYVR EGDDEFDEEE DEAFFARERE IAARAARAAQ SALEPSLIDK VKKKKRKPAP AVRSDDDDED DGDGDVLGLD SDHDDEEEEV ESRDDDTPMA EENDEESESR KKRRVSVVED EAEWDGDVDM EDASNPVNSQ QSESNAKEDG DDAPVVVTRR PRVRGGFVID SDDED // ID G0S825_CHATD Unreviewed; 1212 AA. AC G0S825; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-MAY-2014, entry version 5. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=CTHT_0029130; OS Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae; OC Chaetomium. OX NCBI_TaxID=759272; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 1495 / CBS 144.50 / IMI 039719; RX PubMed=21784248; DOI=10.1016/j.cell.2011.06.039; RA Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., RA Devos D.P., Arumugam M., Bork P., Hurt E.; RT "Insight into structure and assembly of the nuclear pore complex by RT utilizing the genome of a eukaryotic thermophile."; RL Cell 146:277-289(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL988041; EGS21072.1; -; Genomic_DNA. DR RefSeq; XP_006693368.1; XM_006693305.1. DR GeneID; 18256951; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1212 AA; 138543 MW; 44EDDF79997CC0E6 CRC64; MEDGEVNDVV HPQVRAHINS LVSALGGISI DDDGGYKLGD DALEVLRDLK KWIRFYDEKT NRMDVARCLA EANIVSTDLL HILALWTPNE NSNKYKARIA LACFELMVPL TWPIEKDRET MTINHHRHIP VLQLAQLGYK RAIINYDAAP ILSTAVRVAL PAMAMPIGER TARDQGIIKL ILYFLRNIAM ITPPPGVKYE GDESQISRSA LIDAFSYQDI FLTLLTIASN MGEDFRTEDV IVMEIIFHLV KRVDPKKLFV SEKQLSKIKS DELAAAMQRE AAMLRSHGKN MPTRHSRFGT MIWVKRESGK LTTVSGQEAL LDPAARERKM DSTKTFKPPR RARREDMEPK DLGPPVTIDE RARQQLGSFV SDFLDSGFNP LFSHIRKSLE REAPHVLHYH QSQFFYLVAW FLEAERARRR EKKESSKAQS GEDVSSFNLI ASVLTQEMFI ALNRALDRAY GDKDWRLLTS AMRCFTQILL TVQEMFDSGN DEDQEIADNI LSRLFYEEST HDAVANIVRT YKDQGFEYLD ACTELAHTFL RILEAYSKQN VDLQVRSRKR ARRKKKAAKA AAGENGDEDQ DEEDDSADDE KMAEKTSQER KFDFKRFAAR FTPQGVVDTF VTFTKYYRDL DDSQLKRAHR YFYRVAFKQE MSVMLFRLDI IHLFYNMIKG PEPLDKNSPM YKEWEELVRQ ILKRCIRKLE ERPALFTEIL FSKINSTAYY LEYGFEKQTV SSNPRPGAEL EFKRELSRDQ QIAIAVGVLL DRNQTDHLDW IKQQLADAER ERRAWENIDK AMAAERPEGE AASSEGTGFK TTPAYTTVRP DNDARRKAMF KNSHLRLLMK LCGMERLTPT LDESPDSTWI IPGIIDADTL KETLSLINKA EFNPPTFEDG QLAEHQLRRK SAAPRKRAAY DDDGSELQDF LDDGDNGILF PMGPRLKTRK RMAEDGTPPP KKRRRRRRDG SQEPEPLTEE QLEERRRARR KKQLERARRI KSAAYVNPSD DETDEEYDRE FFAKEAAHQA AKDATFGLYD GLPPKPGGVE RSEWEMLIGV DEEDDQPLAD IERRKKSKRK PRAQSQEKSD EEDEESEEEV SDEEFEDIVS DSSSASSPSS PKRPIRLRGR TQLKQPNMSR DTGTNDESDW ERDGGRDGNA MDVDPIQLSH EGPSGQEAGS TVSGGGSGAG EDEDYNDKPV AAAARSRLRA RAGFIIDSSD EE // ID G0V581_NAUCC Unreviewed; 1232 AA. AC G0V581; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 13-NOV-2013, entry version 12. DE SubName: Full=Uncharacterized protein; GN Name=NCAS0A00570; OrderedLocusNames=NCAS_0A00570; OS Naumovozyma castellii (strain ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL OS Y-12630) (Yeast) (Saccharomyces castellii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Naumovozyma. OX NCBI_TaxID=1064592; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 76901 / CBS 4309 / NBRC 1992 / NRRL Y-12630; RX PubMed=22123960; DOI=10.1073/pnas.1112808108; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Evolutionary erosion of yeast sex chromosomes by mating-type RT switching accidents."; RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Type strain:CBS 4309; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Genome sequence of Naumovozyma castellii."; RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE576752; CCC66617.1; -; Genomic_DNA. DR RefSeq; XP_003673008.1; XM_003672960.1. DR GeneID; 11526998; -. DR KEGG; ncs:NCAS_0A00570; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1232 AA; 140759 MW; 101AAE28F3A18101 CRC64; MNNGTGMDAS LTVLRARIAL LATAIGGPDY TSTIEPPPYK LGDDCLACLK DLKRWFKLVD DEQNRWDVAM AAAQYHILVD DLLPILVDWE NKSSLLAKLT RKGKTSDVTI FRNKEYHDKV ALNCLQLLVL MTWPLVITDH SSSNQIALHS ELKKHQLIYK KAILTLENGK VLKAAVRLAL EVIKIDRLSR TPRDNMVIKL ALNFFRNISA IEPADLTVAL GRTLTRGINS VDTLPPNVTL DDISLTAVLT SFQQNKVYDL ILTLANSLSQ EFDQDFINIP LLEVMFFLTK DVSQESLFPM PLSNSNSDYS KHRNDVSKDS LSQTGLQLTN LLKKENELKK NVIQNTSSRH SNFGALLSIQ TPDRGRLTVS GAQNLLNDAK ALQKLDSRKK WNKRKTKRRD DGVGEGLPNS LLNSEGKTSI SSSIRKQFNK FIENFIDSGF NTVLHSVTNY YTTEQDRIVT LEQVEYLLFF GWFLKYQVLR CRFDKSADID MVAEALRETS FILVSSTLRN AYDMKNWIVV HAGMIAFNEL LILLQNCKSE ENDDDIEFII SRLFSDERIQ LLSNLPKTAF KHNYQYMKTC VDLTHTVLKT LEQYATEDRA LIIEGKSRRK KNTGITKEDV ERLVKEEGLD RDEAIDILTP HFTEIEVSFN KVQRSYINEP TIETYVSLLE RFRELEPEYI KKIITFFHRV FIQAKEESLL FKIDIMILLR DMLAPDGIDR TSRVRKHVQR FVDYYLQRLK KRLSSSPAWF VGLLFPSLHD SQVGYFQKYG ENRISKKDSF YGVPPSIFKN IEDQDALPAS VLKDLKYGIL ISTLIDSDKT DLLEKLISHL KHTQDVFSSW LTINVNAEKE TENPPNEIFS IDESTGGKPL LLDRDFRALL KLIGYQIPQN HLEPCYLPGT VEIDDINESI ALVSKYMSTP FETPNGQPSA SYLIRPRTLD GHSHNHDEQD GWTANDDYDY NDPSIIRDED MADDDAYFKE LENGNSKITS ERVSKGVARS KKKSHAKMEQ RKRKRQRNTL AKHDIDDEDG DEQLTKTKAY HEIISKEFIS DSDDDDDEIS NPIFFENEMF LRWLLDKHDG QIPTEKYIQF GKFAAERMAN RGTVISDFSS LFDGTIPSLD QLKYSEGPNH TADKTLMTLS SKVASALSGD AEDNARELTT RNEADSTRDL PTSYQSDSNE DESVIPKNSL NLESEEEEEE EEEEEEDDDE GNMAPTKKRQ KFAIADDSDV SD // ID G0WD81_NAUDC Unreviewed; 1302 AA. AC G0WD81; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 13-NOV-2013, entry version 8. DE SubName: Full=Uncharacterized protein; GN Name=NDAI0F04240; OrderedLocusNames=NDAI_0F04240; OS Naumovozyma dairenensis (strain ATCC 10597 / BCRC 20456 / CBS 421 / OS NBRC 0211 / NRRL Y-12639) (Saccharomyces dairenensis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Naumovozyma. OX NCBI_TaxID=1071378; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 10597 / BCRC 20456 / CBS 421 / NBRC 0211 / NRRL Y-12639; RX PubMed=22123960; DOI=10.1073/pnas.1112808108; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Evolutionary erosion of yeast sex chromosomes by mating-type RT switching accidents."; RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE580272; CCD25742.1; -; Genomic_DNA. DR RefSeq; XP_003670985.1; XM_003670937.1. DR GeneID; 11497080; -. DR KEGG; ndi:NDAI_0F04240; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1302 AA; 149006 MW; 7AABF3D4B2325220 CRC64; METNASTVLK ARIALLATAI GGPDYASNIE PPPYKLGDDC LACLRDLKRW FKLVDDEQNR WDVAMAAAEY RILTDDLIPI LIDWENKSSA LTKLQNKNND QTVMENIETT LGFRNKVYYD KVALSSLQLL VLMTWPLVLT DQSTSSQIAV YSELKKHQLI YKKEILTVDN GKVLKAAIRL ALNVFKIDRL SRTPRDNMII KLVLNFFRNV ASIEPGNLTI TVGRSLPRGI NSIDTLPPNV TMDDISLNAV LNCFHRNKVY GLLLTLSSSL TTEFDQDFIN IPLLEIMFFL TKDVPQQALF PVPSPKTRST TKNKDRQENV TIPSHSSYTG FQLSDLLKKE NEMKKNVIRN TSTRHSNFGA LLSVQTPNGR ISVSGTQGLL DDAKALDKID RRKKWNKRRV TKYENNPGQG LPNSLLNSQG TSFYFQESTL KYFKKFINNF IGSAFNTLLH SITNYYTTEQ DRVVTLEKVE YLLFFGWFLK YQVLRCKYDP TADITMVSGA LRETSFILVL SFLRTAYEMK HFIVVHAGMI AFNELLVLVQ NCKAKENDED IEFIISKLFS NERIQLLSNL PKTAFKHTHQ YMKSCVDITH TVLKTLEQYT SEDKALIIEG KSRRRRNISV TKEQIEQLIK EEGVDRDEAI DMLTPHFVEV EVNFERVQRS YINEQTIDTY MNFLQRYDEL EPEYIKKVIT FFHRVFIQAK EETMLFRLDL IVLFRDMLAP DGIDRTSRVR KHVQDFVDYY LNRLNKKLKS SPTWFIDILF PSIHDSEIGY FQRYGERKAK ANASLFGVPP SVFKNIEDEH MLPPAVLKDM KYGILVSSLI DDDKTELLEK LIEHIKRAID IFSSWLTVNI NNGNETANPP NETFKLQEVS ARNPLLSDKD FRALLQLIGY QIPMNHLEQC ILPGTVEITA LKESLELVKK YMNSPFETPN GLPSSSYLLR PRSKFHGDDA GESDGWVGNE EYDYNDRSII NDDEVIPDDN DYFKDLGNAE NSIERSNHKG IAKSKRKPKS TARNTKKPIR RRGNRLPDHD IDDEDDEGTT HYKRSHQAIS SKEYISDSDD DEDELMNPIF FENEMYLRWL LDKHNGQIPP EKNIRFAQFA AERMANNGET TSNFIELFDG PIPNLDALKS SEDGTATKQP DNTLKDLSAH VAFSLVENKS TCDTSSSTDD DAQTSTATSL QQNRASDDDE EEQEGENGDA TGSDRVEHGG QITTTRLRKH HLDSDDGENE EDGENGGDTA GISSKHDDDT VKEREEEENN EEEGEMASSD SEVTPRKKRK QIFKLRPEQD PSEPDHPLVW PY // ID G0YQM6_SPOEX Unreviewed; 1054 AA. AC G0YQM6; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 03-OCT-2012, entry version 3. DE SubName: Full=Timeless; OS Spodoptera exigua (Beet armyworm) (Noctua fulgens). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Noctuoidea; Noctuidae; Amphipyrinae; Spodoptera. OX NCBI_TaxID=7107; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Larvae head and male antenna; RA Niu X.-H., Dong S.-L.; RT "Circadian genes in Spodoptera exigua."; RL Submitted (DEC-2010) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HQ731035; AEJ38225.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1054 AA; 118634 MW; 5C30A18A6A840823 CRC64; MVQLIALLYK DQHVVTLHKL LNLWIEASLS ESSEDNESNT SPPDRGSDSS PMCTSEPTSD SSDTGGSGKS NDDPNSVNKD WDASSQMNNT SENGNPPFQT TEEKESDNED KNNSIESNND EIVQSDNGQS SSCSGGAQSS RNGQGQQPGN TEKKTVISEN SDCGYGTQIE NQESISTSSN EDELPSKKPV HQKPHNPKQR VNNKARSGVT MQDRKRKKIV KRGKSNIINV QGLSHKTPTD DDISNVLKEF TVDFLLKGYN SLVQTLHNQI LSNLQLEIDT SHFFWLVTYF LKFATQIELD LENVSSVLSI DIVSYLTAEG VNLCEQFELA IKLDGNDLKP NIRRLHLVVT AIREIIQAID VYKKFSHICK EDQEALLKLQ LKMCETEELR SLLVLLLRHY NPKYHSKQYL QDVIVTNHIL LMFLDSAMKL PEYNGSTNML DHIRQFASSE IMYQYGLLLE DCAGNGEFVN DCILTLMHHV GGELESLITL FQPKILKTFT SIWKSEFEIC DDWSDLIEYV INTFIKKPHS LQSSANFRLD IENFDDVKII PKPTVALPAQ SKSETVEAEE KKPTTKSNTS CISNGKGESR WTEDELSSLS WNYMQCSALP DVVGEIITLY KEDGIIKSRD SVIKELYTQN LINKEDYDKF VKGENDRNIK TVQVMKEMRD DEINKLCEQL TQDGKSKFLD WVQKVLLETC FAKIYLDKLA RKSEGDNTIE ENETKLSKLK KSNDLHILSP VSYHSLLMNQ SIPLVPWNCK QASICKDLKF LQLLHKLGFH MPVDSGKVFI RIPHFWTADF LYDVAGKISP IDKSKLKFSI NDISDSSISN SMQQENLLLL PDLTKDISMI ENSDNFYQIH KQKHLATMVN FTPMPSSSFN SEGGDVDKHN WLEVVQKSQE YKIALNLGSS IIKSDEEAQS DIVNLQQLPV KDTEVSVPPL LLATGPVAIG STATVTGASF PASGLMMPTI MSIKQETTHF NLPVPDSEHY SVCETASVAS DLTRMYVSDE DEKPEVVRPI IAVNPIHDES DELCGDLDDD NSGKRPRVNY FSSF // ID G1KSP3_ANOCA Unreviewed; 1204 AA. AC G1KSP3; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 26-JUN-2013, sequence version 2. DT 03-SEP-2014, entry version 19. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Anolis carolinensis (Green anole) (American chameleon). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; OC Toxicofera; Iguania; Iguanidae; Polychrotinae; Anolis. OX NCBI_TaxID=28377; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RG The Genome Sequencing Platform; RA Di Palma F., Alfoldi J., Heiman D., Young S., Grabherr M., Johnson J., RA Lander E.S., Lindblad-Toh K.; RT "The Genome Sequence of Anolis carolinensis (Green Anole Lizard)."; RL Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR RefSeq; XP_003217047.1; XM_003216999.2. DR Ensembl; ENSACAT00000016556; ENSACAP00000016233; ENSACAG00000016465. DR GeneID; 100555324; -. DR KEGG; acs:100555324; -. DR CTD; 8914; -. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 2. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1204 AA; 140171 MW; 2B95573F9B07DB00 CRC64; MDLYMMNCEL LATCSALGFL EGDIYHKEPD CLESVKDLIR YLRHEDETRD IRQQLGAAQI LQNDLIPVIV QYPQDKQLFD AVIRLMVNLT QPAVLCFGKL PQDASFRHHF LQIVSYLQAY KEAFANEKIF GVLSEKLYNL LQLDWEQRQE EDNLLIERIL LLVRNVLHIP ADPDEEKNID DDANTHDRVL WAIHISGMDD LLKFLASSQS EQQWSLHVLE IISLMFRDQK PDQLAATGQG RSAKERVTDI AELEILRQKE LTEKKNRVLQ RSSRHSRFGG CYVIQGLKSI GERDVVMHKS LHNVKNYSHD LGKEVRRVPK RRQLAHDSES TSRRSALNVR FFLKEFCVEF LENCYNRLMC LVKDHLMRER AQQHDETYYL WAIAFFMAFN RAYSFQPQLV SETVGVRTFH FIEQSLTNYY EMLLMDKKEA TSWSRRMHLA LKAYQELLMT MHEMDHSQDE TIRHSSHILK NNIFYMMEYR ELFLTLFRKF DETKQPRSFL KDLVETTHLF LKMLERFCKG RNNLVVQSKK VKRKKRQTRP AGSDVQIRTS EELEEMWPRL VDQISKCIKN SEPLPEDVVP FDAASEVPLE EQRAEAMVRI QDSLLAGRGP EALSLLRSAR EVWPEGDIFG SSSLDPDEET ELLKQLFFAN LPRRMIPEVE ESEEAAEEEE VAEEELASVH VSEKEFSFLD YMKRFASAHV VKAYILLLKN YQQNSSHTNH CIVKMLHRIA CDLKMEALLF QLSIFCLFNR LLNDPAAGAY KELVTFAKYI VGKFFALAST NKKAYMELLF WKNTAVVREM IEGYSSLQDG SSDSCKASRW TEEEDEELRE LYYKYKEVEG EDILNNILAH LNNRSRTRKQ VAKQLVRLGL ANSMRDFPQE RKGTRIVLWT EDQELELRRL FEEYQNADDI LANVMRHITA KRSKARIIEK LLSMGLVSDR KELYKKRQRK SGSCGTKKGA FSKDFRALDL DEVDEGEEEE EEEDEDDNLD SEDDEEPTQN DGNNSTGNRS QDKQTNKKWG SASDRGINTL VRSLRQEGLS GPLLWIQSCL NRTAADREED GCTQPVPLVP LSEENEDAME HKNFQKLLRK MGLRAPANEQ ESFWRIPSKL SPEQLQRIAA SISLQEVERE TQEQLAVSEE DHLDTEEPRE EPIQCPQGPK RSRLLSDSEE EGEESHHPGS CDEDELRPSG KRKRLRIEEE DEED // ID G1LBC9_AILME Unreviewed; 1207 AA. AC G1LBC9; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Ailuropoda melanoleuca (Giant panda). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; OC Ailuropoda. OX NCBI_TaxID=9646; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=20010809; DOI=10.1038/nature08696; RA Li R., Fan W., Tian G., Zhu H., He L., Cai J., Huang Q., Cai Q., RA Li B., Bai Y., Zhang Z., Zhang Y., Wang W., Li J., Wei F., Li H., RA Jian M., Li J., Zhang Z., Nielsen R., Li D., Gu W., Yang Z., Xuan Z., RA Ryder O.A., Leung F.C., Zhou Y., Cao J., Sun X., Fu Y., Fang X., RA Guo X., Wang B., Hou R., Shen F., Mu B., Ni P., Lin R., Qian W., RA Wang G., Yu C., Nie W., Wang J., Wu Z., Liang H., Min J., Wu Q., RA Cheng S., Ruan J., Wang M., Shi Z., Wen M., Liu B., Ren X., Zheng H., RA Dong D., Cook K., Shan G., Zhang H., Kosiol C., Xie X., Lu Z., RA Zheng H., Li Y., Steiner C.C., Lam T.T., Lin S., Zhang Q., Li G., RA Tian J., Gong T., Liu H., Zhang D., Fang L., Ye C., Zhang J., Hu W., RA Xu A., Ren Y., Zhang G., Bruford M.W., Li Q., Ma L., Guo Y., An N., RA Hu Y., Zheng Y., Shi Y., Li Z., Liu Q., Chen Y., Zhao J., Qu N., RA Zhao S., Tian F., Wang X., Wang H., Xu L., Liu X., Vinar T., Wang Y., RA Lam T.W., Yiu S.M., Liu S., Zhang H., Li D., Huang Y., Wang X., RA Yang G., Jiang Z., Wang J., Qin N., Li L., Li J., Bolund L., RA Kristiansen K., Wong G.K., Olson M., Zhang X., Li S., Yang H., RA Wang J., Wang J.; RT "The sequence and de novo assembly of the giant panda genome."; RL Nature 463:311-317(2010). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACTA01162064; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSAMET00000004370; ENSAMEP00000004203; ENSAMEG00000003946. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1207 AA; 138683 MW; 94E51B589E70C8F8 CRC64; MDLNMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDDTRD VRQQLGAAQI LQSDLLPILI QHRRDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLAYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP TDLDQEKRID DDASVHDQLL WAVHLSGLDD LLLFLASSPA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSTDV AELEVLRQRE MAEKKTRALQ RGNSRHSRFG GSYIVQGLKS IGERDLIFHK GLHNLQNYSS DLGKQPRRVP KRRQAARELS VQRRSALNVR LFLRDFCSEF LENCYNRLMG SVKDHLLREK AQQHDETYYM WALAFFMAFN RAASFRPALV SETLSVRTFH FIEQNLTNYY EMMLTDRKEA ASWARRMHLA LKAYQELLAT VNEMDMSPDE AVRESSRIIK NNIFYVMEYR ELFLALFRKF DERCQPRSFL RDLVETTHLF LKMLERFCRS RGNLVVQNKR KKRKKKKKVL DWPVAPGNVP SSAGELEAVW PSLAEQLQCC AQDPELSLDS VVPFDAASEV PVEEQRAEAM VQIQDCLLAG QAPQALTLLR SAREVWPEGD VFGSQDISAE EELQLLKQIL CAPLPRQQGP EDRGPEEEEE EEEEEEVQAV RVSEKEFNFL DYLKRFASST VVRAYVLLLR GYRQNGAHTN HCIVKMLHRL AHDLKMDALL FQLSLFCLFN RLLSDPAAGA YTELVTFAKY ILGKFFALAA VNQKAFVELL FWKNTAVVRE MAEGYGSLDG GSSSRKPPIW TPEEEAQLQE LYLAHKDVEG QDVVDVILAH LKTPRTRKQV IHQLVRLGLA DSVKEFQRKG THIVLWTEDQ ELELQRLFEE FQDSDDVLGH IMKNITARRS RARIVDKLLA LGLVAERREL YKKRRKKLAP SSSPKGEESR KDFCQEDLEE EENLPEEESD EDEEKEEDSE ADKAERSPVL SAETLGQSLS QEGFSAPLLW LQSCLMRVAD DREEDGCSQP VPLVPLTEEN EEAMENEQFQ QLLRKLGVRP PASGQETFWR IPAKLSPTQL RRVAASLSQP EEELQPGPEP KVPGEQGPEE EHKKEHRSQA RRALVLARKE KAGLVSPEEE GAAGEKEQLK MAPRKRQLLD SDEEQEEDEG RSKAPESRAP EIQKKKRFQI EDEDESD // ID G1P7X4_MYOLU Unreviewed; 806 AA. AC G1P7X4; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-MAY-2014, entry version 16. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Myotis lucifugus (Little brown bat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Chiroptera; Microchiroptera; OC Vespertilionidae; Myotis. OX NCBI_TaxID=59463; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., RA Lindblad-Toh K.; RT "The genome sequence of Myotis lucifugus (Bat)."; RL Submitted (JUL-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21993624; DOI=10.1038/nature10530; RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., RA Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., RA Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., RA Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S., RA Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., RA Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., RA Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., RA Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., RA Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., RA Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., RA Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., RA Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., RA Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., RA Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., RA Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., RA Pedersen J.S., Lander E.S., Kellis M.; RT "A high-resolution map of human evolutionary constraint using 29 RT mammals."; RL Nature 478:476-482(2011). RN [3] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAPE02026862; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMLUT00000006833; ENSMLUP00000006240; ENSMLUG00000006822. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 806 AA; 93010 MW; 152F5DEA04EE504D CRC64; TMNCELLATC SALGYLEGDT YHKEPDCLES VKDLIRYLRH EDETRDVRQQ LGAAQILQSD LLPILTQHRQ DKALFDAVIR LMVNLTQPAL LCFGSVPKEP SFRHHYLQVL AYLQAYKEAF ASEKAFGVLS ETLYELLQLG WEERQEEDNL LIERILLLVR NILHIPADPD QEKRIDDDAS VHDQLLWATH LSGLDDLLLF LASSPTEQQW SLHVLEIISL MFRDQNPEQL AGVGRGRLAQ ERSTDVAELE MLRQRELAEK KTRALQRGNR HSRFGGSYIV QGLKSIGERD LIFHKGLHNL RNYSSDLGKQ PRRVPKRRQA ARELSIQRRS ALNVRLFLRD FCSEFLENCY NRLMGLVKDN LLREKAQQHD ETYYMWALAF FMAFNRAASF KPGLVSETLS VRTFHFIEQN LTNYYEMMLT DRKEAASWAR RMHLALKAYQ ELLATVNEMD VSPEEAVRES SRIIKNNIFY VMEYRELFLA LFRKFDERCQ PRSFLIDLVE TTHLFLKMLE RFCRSRGNLV VQNKRKKRKK KKKPVASGNV PCSPGDLEAL WPSLAEQLQC CAQDPELSLD SMVPFDAASE VPVEEQRAEA MVRIQDCLLA SQAPQALTLL RSAREVWPEG DAFGSQDISP EEEIQLLKQI LCAPLPRQRG PEERGAEEEE EEEEEEEEEE ELQAVQVSEK EFNFLDYLKR FASSAVVRAY VLLLRSYKQN SAHTNHCVVK MLHRLAHDLK MEALLFQLSL FCLFNRLLSD PAAGAYRELV TFAKYILGKF FALAAVNQKA FVELLFWKNT SVVREMTEGY GSLDGG // ID G1S6U2_NOMLE Unreviewed; 1210 AA. AC G1S6U2; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 19-OCT-2011, sequence version 1. DT 14-MAY-2014, entry version 12. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Nomascus leucogenys (Northern white-cheeked gibbon) (Hylobates OS leucogenys). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hylobatidae; Nomascus. OX NCBI_TaxID=61853; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RG Gibbon Genome Sequencing Consortium; RL Submitted (JAN-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ADFV01002419; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ADFV01002420; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSNLET00000022307; ENSNLEP00000021231; ENSNLEG00000017486. DR GeneTree; ENSGT00390000015124; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1210 AA; 138850 MW; D0B640B828647A2B CRC64; MNLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRYEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADV AELEVLRQRE MAEKKARALQ RGNRSSRLQC ATIASLHSNL GDRVLVSKQK QKLLRNYSSD LGKQPRKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFQPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDISPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GKLVVQNKRK KRRKKKKKVL DQAIVSGNVP SSPEEVEAVW PALAEQLQCC AQNSELSMDS MVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQALTLLR CAREVWPEGD VFGSQDISPE EEIQLLKQIL SAPLPRQQGP EECGAEEEEE EEEEEEEEEE LQVVQVSEKE FNFLDYLKRF ACSTVIRAYV LLLRSYQQNS AHTNHCIVKM LHRLAHDLKM EALLFQLSVF CLFNRLLSDP AAGAYKELVT FAKYILGKFF ALAAVNQKAF VELLFWKNTA VIREMTEGYG SLEDRSSSRR APTWSPEEEA HLRELYLAHK DVEGQDVVEA ILTHLNTAPR TRKQIIHHLV QLGLADSVKD FQRKGTHVVL WTGDQELELQ RLFEEFRDSD DVLGHIMKNI TAKRSRARIV DKLLALGLVA ERRELYKKRR KKLASSILPN GAESLKDFCQ EDLEEEENLP EEDSEEEEEG GSEAAQVQGS LILSTENLGQ SLHQEGFSAP LLWLQNCLIR AADDREEDGC SQAVPLVPLT EENEEAMENE QFQQLLHKLG VRPPASGQET FWRIPAKLSP TQLRRVAASL SQPEEEQKLQ PELQPEVPGE QGSDEEHCKE HRAQALRALL LAHKKKAGLA SPEEEDAVGR EHLKAAPKKR QLLDSDEEQE EDEGRNRAPE SGAPGIQKKK RYQIEDDEDD // ID G1T2J2_RABIT Unreviewed; 1201 AA. AC G1T2J2; DT 19-OCT-2011, integrated into UniProtKB/TrEMBL. DT 13-NOV-2013, sequence version 2. DT 16-APR-2014, entry version 10. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Oryctolagus cuniculus (Rabbit). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; OC Oryctolagus. OX NCBI_TaxID=9986; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Thorbecke; RG The Genome Sequencing Platform; RA Di Palma F., Heiman D., Young S., Gnerre S., Johnson J., Lander E.S., RA Lindblad-Toh K.; RT "Genome Sequence of Oryctolagus cuniculus (European rabbit)."; RL Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Thorbecke; RX PubMed=21993624; DOI=10.1038/nature10530; RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., RA Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., RA Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., RA Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S., RA Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., RA Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., RA Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., RA Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., RA Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., RA Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., RA Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., RA Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., RA Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., RA Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., RA Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., RA Pedersen J.S., Lander E.S., Kellis M.; RT "A high-resolution map of human evolutionary constraint using 29 RT mammals."; RL Nature 478:476-482(2011). RN [3] RP IDENTIFICATION. RC STRAIN=Thorbecke; RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAGW02059152; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAGW02059153; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSOCUT00000012061; ENSOCUP00000010377; ENSOCUG00000012057. DR GeneTree; ENSGT00390000015124; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1201 AA; 137735 MW; 3CCABE328477E479 CRC64; MDLYMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVVRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLTYLQAY KEAFASDKTF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLEQEKSID NDASVHDQLL WAIHLSGLDD LLLFLASSPA EQQWSLHVLE IISLMFRDQN PEQLARAGQG RLAQERSTDV AELEVLRQRE MAEKKTRALQ RGSRHSRFGG SYIVQGLKSI GERDLVFHKG LHSFQNYTSD LGKQPRRVPK RRQAAQELSS QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMFPDEA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERCQPRSYLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRKKKKKVLD QAAASGNVPG SPGELEAMWP ALAEQLQCCV QSPELSADSM VVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQALSLLR SAREVWPEGD VFGSPDVSPE EETQLLKEIL CAPLPRQQGP EEQGAEEEEE EEEEEELQEV QVSEKEFNFV DYLKRFACST VVRAYVQLLR SYQHNSAHTN HCATKMLHRL AHDLKMEALL FQLSVFCLFN RLLSDPAAGA YKELVTFAKY ILGKFFALAA VNQKAFVELL FWKNTAVVRE MTEGYGSLDA GSSSRRAPAW SPEEETQLRE LYLAHKDVEG EDVVEAILAR LKTVPRTRKQ VIHHLVQLGL ADSVKDFQRK GTNIVLWTED QELELQRLFE EFQDSDDVLG HIMKNITAKR SRARVVDKLL ALGLVTERRE LYKKRRKKPA PSSLPNGKES LKDFSQEDLE EEENLPEEES EGDEETEEGW EVEQVQGSSA FTTESLGQGL RQEGFSAPIL WLQNCLIRVA EDREEDGCSQ AVPLVPLTEE NEEAMENEQF QQLLRKLGVR PPASGQETFW RIPAKLSPTQ LRRAAASLSQ LEERGEKLQP EQDSEVPGEQ GPSEEHRAEA LQALVLARKK KASLATPEEE GTADEQEQLT AAPKKRQLLD SDEEQEEAPE LGAPRTQKKK RFQIEDEDES D // ID G1X2S8_ARTOA Unreviewed; 1044 AA. AC G1X2S8; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 22-JAN-2014, entry version 5. DE SubName: Full=Uncharacterized protein; GN ORFNames=AOL_s00043g1; OS Arthrobotrys oligospora (strain ATCC 24927 / CBS 115.81 / DSM 1491) OS (Nematode-trapping fungus) (Didymozoophaga oligospora). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes; OC Orbiliales; Orbiliaceae; Orbilia. OX NCBI_TaxID=756982; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24927 / CBS 115.81 / DSM 1491; RX PubMed=21909256; DOI=10.1371/journal.ppat.1002179; RA Yang J., Wang L., Ji X., Feng Y., Li X., Xou C., Xu J., Ren Y., Mi Q., RA Wu J., Liu S., Liu Y., Huang X., Wang H., Niu X., Li J., Liang L., RA Luo Y., Ji K., Zhou W., Yu Z., Li G., Liu Y., Li L., Qiao M., Feng L., RA Zhang K.-Q., Ji K., Wang L., Zhang K.; RT "Genomic and proteomic analyses of the fungus Arthrobotrys oligospora RT provide insights into nematode-trap formation."; RL PLoS Pathog. 7:E1002179-E1002179(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ADOT01000056; EGX52507.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1044 AA; 118283 MW; 8B1804720C97E7AF CRC64; MDITGQPSQK SSADGVDPIL RSHIYGLVSA LGGPSPDDPN TYILGDDVFG CLRDIKRWLK GYDEKLDRLD VARCLSEANL VVDLMEILSH TSTKGISTLN HPNKIGLACV ELLVPLTWPL NKTELSMTVN HHRHLAVLRR SQAYYKKNIL THQSGCILKA CCVNALPPMA VALPERTPRD EGIIRLVLYL IRNLLQIEEL ELENDNVWNE ISKSSTIEAF DGQGIFDLLL SIISGVPELF QQQDVIVVEI LFHLLLGVDM RQFVTSAPDA GVMKTLDPLA HILKTETPSA GLKAQSRHTR FGTTVVLKNE DGQNKVVTGH SALLAESTGL RKLDDAKKWR KPQHNVNKKH TINEGLVSPL RLADYQEALF QNVRKAIERD SKRILGNTHI AQLFFVGGSL MEFGRGMKQG GAMLGDPRTL RSREFSTLLQ PETFIILFRH IREGLESKSW DYVQSGCHYF TQALLVVSEM MHSQDHDEKS LAENIFNRLF YEETLHDLMI AVLRSGRKQT VEYLDILTQM IHVYLRCLER YCKSNSGLIV KSKRASKSHS GEIEAFSDSE SDTKMPDRKQ AEKSFNFQQY ESKFLSPASL EPFLDLLSHY RELGWPQIKR CIGFLHRVFV KRGATVGLFH LKAIYILQAV ARDTKGSQGY TEIAGFVRFF SKHLVRKLSE YPVLFVEILF QKSQRIGYFI EHGEDRSRCN RELPPSLTIE LEEGLDKEKR IAVAVWLVSQ DDVCCKQFGW VERVLYCVVE ERRGWETKDS SVHPNKGPGD LRKLCPIAVK FEGDTHTQLH FSSNKLQLLM KVLDFEPEGS HPQEFCYVLP DTVSFQTLQE SITTFLRYMK SPISEFGDGK ALVDCFTMKR KKIELKSSDS SGEWKKDSAS EAFEPEFPDN LKARKSRSTK GPEVRLAKKM NMDENEAHRR REEHKLKERE RRRGIKSGLY IGSSDDDSDY ERDQEFFEKE RVLREAMSKA TLHADGNGQP DMPLARQKRS ILDETARESK RLKTKFNSDG SDSGNNSGNG GGNDSSNDIG RDSSESGNDS GGSE // ID G2Q940_THIHA Unreviewed; 1231 AA. AC G2Q940; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 19-FEB-2014, entry version 10. DE SubName: Full=Uncharacterized protein; GN ORFNames=MYCTH_2301111; OS Thielavia heterothallica (strain ATCC 42464 / BCRC 31852 / DSM 1799) OS (Myceliophthora thermophila). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae; OC Myceliophthora. OX NCBI_TaxID=573729; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 42464 / BCRC 31852 / DSM 1799; RX PubMed=21964414; DOI=10.1038/nbt.1976; RA Berka R.M., Grigoriev I.V., Otillar R., Salamov A., Grimwood J., RA Reid I., Ishmael N., John T., Darmond C., Moisan M.-C., Henrissat B., RA Coutinho P.M., Lombard V., Natvig D.O., Lindquist E., Schmutz J., RA Lucas S., Harris P., Powlowski J., Bellemare A., Taylor D., Butler G., RA de Vries R.P., Allijn I.E., van den Brink J., Ushinsky S., Storms R., RA Powell A.J., Paulsen I.T., Elbourne L.D.H., Baker S.E., Magnuson J., RA LaBoissiere S., Clutterbuck A.J., Martinez D., Wogulis M., RA de Leon A.L., Rey M.W., Tsang A.; RT "Comparative genomic analysis of the thermophilic biomass-degrading RT fungi Myceliophthora thermophila and Thielavia terrestris."; RL Nat. Biotechnol. 29:922-927(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP003003; AEO56332.1; -; Genomic_DNA. DR RefSeq; XP_003661577.1; XM_003661529.1. DR GeneID; 11510382; -. DR KEGG; mtm:MYCTH_2301111; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1231 AA; 138802 MW; 52E56C87B38BF905 CRC64; MEDELNNDTV HPQVRAHITS LVSALGGYSL DDDDGYKLGD DALEVLRDLK KWIRFYDEKT NRMDVARCLA EANLVGSDLL HILALWSPND SSKYKARIAL ACLEVMVPLT WPIEKDRETM TVNHHRHLPV LQLAQLGYKR AIINFDAAPI LGTAVRVALP SMAIPIGDRS ARDQGIIKLM LYFLRNIAMI APPPGVKYEG DETQISRSAL IDAFSFQDIF LTILTIASNM GEDFRTEDVI VMEIIFHLVK RVDSSKLFVS EKRLHKMKED ELTAAMKKEA AMLRSYSKNA PTRHSRFGTM IWVKRESGKL ATVSGQDALL DAATRERKMD NSKSFRPPRR ARREDMEPKD LGPPVSLDER ARQQLQSFVS DFLDSGFNPL FSHVRRSIDR EAPHVLPSHS SQFFYLVAWF LEAERMRRKA KNDSKKPSAE DDVGSFNLVA EVLNQEMFIT LNRALNRAYG DKDWRLLTTV MRCFTQILLT VQEMFASGNE EDEEIADNIL SRLFYEETTH DAIANIVRTY KDQGFEYLDA CTELTHTFVR ILEAYSKQNV DLQVRSRKRR RRRKKAANKA AGDDGGDEDQ DDAEDDSADD ERQAEKTSQE RKFDFKRFSL RFVPQGVVDT FVTFTKYYRD LDDSQLKRAH RYFFRLAFKQ DMSVMLFRLD IIHLFYHMIK GPEPLDKNSS MYGEWEELVK QILRKCIKKL AERPALFTEL LFSKINSTAH YLEYGHEKQT VSSNPRPAAE LEFKREVDRE RQIAIVVGVL IDRNQTDHLD WLKKQLTEAE SERRAWEEAE KARAADGLDG EAAGGTVETG AAKVAPHATI RPDNDARRAA MFKNPHLRLL MKLVGLERLA PTLDETPDSV WVVPGSIPAD SLKETISLIN QAEFNPPTFE DGELAEDQLR RKSAARRRAA HDDDGGDNGI NDFINDGSEE DDDDGAGILF PRGGPTTRKR TAEDEPPPPP KRKRRRRRGS DEAETDEQRE ARARARRKKE RERARRIKSA MYVDLREDDS DWEGNKEADR EFFARERERQ AAKDASFGLV SGSRPSGVGV ELWEELLGLG AAASDGEDGE DGGARRGRKR KSVGDDGDSD GDALSDDDQD DDGATAESES GSSSSSSSSS SARRPNKRRR TTQKKKNKAA EISSDEDEDE DMTGADDAMD STQSSKDGAV TNDTPLSSSP GRQTADAAAE KAGERADGMG DEDDDVPVAK AATRGRPRAR AGFIVESSDE E // ID G2QTQ6_THITE Unreviewed; 1214 AA. AC G2QTQ6; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 11-DEC-2013, entry version 7. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=THITE_2107323; OS Thielavia terrestris (strain ATCC 38088 / NRRL 8126) (Acremonium OS alabamense). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae; OC Thielavia. OX NCBI_TaxID=578455; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 38088 / NRRL 8126; RX PubMed=21964414; DOI=10.1038/nbt.1976; RA Berka R.M., Grigoriev I.V., Otillar R., Salamov A., Grimwood J., RA Reid I., Ishmael N., John T., Darmond C., Moisan M.-C., Henrissat B., RA Coutinho P.M., Lombard V., Natvig D.O., Lindquist E., Schmutz J., RA Lucas S., Harris P., Powlowski J., Bellemare A., Taylor D., Butler G., RA de Vries R.P., Allijn I.E., van den Brink J., Ushinsky S., Storms R., RA Powell A.J., Paulsen I.T., Elbourne L.D.H., Baker S.E., Magnuson J., RA LaBoissiere S., Clutterbuck A.J., Martinez D., Wogulis M., RA de Leon A.L., Rey M.W., Tsang A.; RT "Comparative genomic analysis of the thermophilic biomass-degrading RT fungi Myceliophthora thermophila and Thielavia terrestris."; RL Nat. Biotechnol. 29:922-927(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP003009; AEO62766.1; -; Genomic_DNA. DR RefSeq; XP_003649102.1; XM_003649054.1. DR GeneID; 11521672; -. DR KEGG; ttt:THITE_2107323; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1214 AA; 137852 MW; 287038ECAFEDC1B6 CRC64; MEDPELSSDT VDPQVRAHIN SLVSALGGYS IDDDDGYKLG DDALEVLRDL KKWIRFYDEK LNRMDVARCL AEANLVGTDL LQILATWRPN DSASKYKARI ALACFEIMVP LTWPIEKDRE TMTVNHHRHL PVLQLAQLGY KRAILNFDAA PILGTAVRVA LPSMALASGD RSARDQGIIK LILYFLRNIA MISPPPGVKG DGDETYVSRS ALVDAFSYQD VLLTLLTMAS NMGDDFRTED VVVMEIIFHL VKRVDSSKLF VSEKQLHRIK AEELTAAMKK EAAMLRSYNK NAPTRHSRFG TMIWVRRESG KLSTVSGQDA LLDAATRERK MDSSKSFKPP RRARKEDIES KDLGPPVNLD ERARKQLQDF VSEFLDSGFN PLFGHVRRSL DRDAPHVLQY HHSQFFYLVA WFLEAERARR NAQKESKQPS TGDEVGSFNL VAEVLSQEMF ISISRALDRA YGDKDWRLLT TVMRCLTQIL LTVQEMSQSG NEEDEEIADN ILSRLFYEET THDTIANIVR TYKDQGFEYL DACTELTHTF VRILEAYSKQ NVDLHVRSRK RRRRKKKAAR AEGQQAADDD HGDSEDDSAD DARQAEKTSQ ERKFDFKRFA LRFIPQGVVD TFVTFTQYYR DLNDAQLKRA HRYFYRVAFK QEMSAMLFRL DIIHLFYNMI KGPEPLDRNS SMFKEWEELA KQIIRKCVRK LEERPALFVE LLFSKTNSTA HYLEYGYEKQ TVSANPRPAA ELEFKREVER DRQIAIVVGV LLDRNQTDHL EWIKKQISEA EAERRAWENA EQALATERPD GEAAREPKMA PHSTLRPDND ARRTAMFKNA HLRLLMKLVG AERLAPTLDE TPDSIWIIPG TVTADALKET LSLINQAEFT PPTFEDGTLA EDQLRRKSAA RKRAAYDDDD DRGDIHDFVN DNSEDDDTGI LFPAGGPTVR RRTAEDEPPA QKRLRRGRRR REGSEEPAPL TDEQLAERAR ARRKKELERA RKIKSAVYVD PRDDMSDDER DREFFAKELA RQEAKNASFG LSSKPSGVEM STWEELLGVD GSGVDDDHEG KDGGSKTGRE RARQTRKRKS DAGPAESSED EDAGTSSTAS DSGLESEERP ARRARKRRKS ARPVGSGSEE EDRAGEDGMD VDVRSTQSSK DEVVTNDTPL SSSPSRTAMA TAEKVAADGE RREDEDDDVP VAKVTARARP RARAGFIVES SDEE // ID G2WLJ3_YEASK Unreviewed; 1238 AA. AC G2WLJ3; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=K7_Tof1p; GN Name=K7_TOF1; ORFNames=SYK7_060641; OS Saccharomyces cerevisiae (strain Kyokai no. 7 / NBRC 101557) (Baker's OS yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=721032; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Kyokai no. 7 / NBRC 101557; RX PubMed=21900213; DOI=10.1093/dnares/dsr029; RA Akao T., Yashiro I., Hosoyama A., Kitagaki H., Horikawa H., RA Watanabe D., Akada R., Ando Y., Harashima S., Inoue T., Inoue Y., RA Kajiwara S., Kitamoto K., Kitamoto N., Kobayashi O., Kuhara S., RA Masubuchi T., Mizoguchi H., Nakao Y., Nakazato A., Namise M., Oba T., RA Ogata T., Ohta A., Sato M., Shibasaki S., Takatsume Y., Tanimoto S., RA Tsuboi H., Nishimura A., Yoda K., Ishikawa T., Iwashita K., Fujita N., RA Shimoi H.; RT "Whole-genome sequencing of sake yeast Saccharomyces cerevisiae Kyokai RT no. 7."; RL DNA Res. 18:423-434(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DG000050; GAA25835.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141171 MW; 2F524D0AA09BC2A7 CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMKKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFIKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKTAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEDDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGIL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK GSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKLSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTNLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRTLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDE // ID G2XED3_VERDV Unreviewed; 1098 AA. AC G2XED3; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 19-MAR-2014, entry version 5. DE SubName: Full=Topoisomerase 1-associated factor 1; GN ORFNames=VDAG_08518; OS Verticillium dahliae (strain VdLs.17 / ATCC MYA-4575 / FGSC 10137) OS (Verticillium wilt). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Glomerellales; OC Plectosphaerellaceae; mitosporic Plectosphaerellaceae; Verticillium. OX NCBI_TaxID=498257; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VdLs.17 / ATCC MYA-4575 / FGSC 10137; RX PubMed=21829347; DOI=10.1371/journal.ppat.1002137; RA Klosterman S.J., Subbarao K.V., Kang S., Veronese P., Gold S.E., RA Thomma B.P.H.J., Chen Z., Henrissat B., Lee Y.-H., Park J., RA Garcia-Pedrajas M.D., Barbara D.J., Anchieta A., de Jonge R., RA Santhanam P., Maruthachalam K., Atallah Z., Amyotte S.G., Paz Z., RA Inderbitzin P., Hayes R.J., Heiman D.I., Young S., Zeng Q., Engels R., RA Galagan J., Cuomo C.A., Dobinson K.F., Ma L.-J.; RT "Comparative genomics yields insights into niche adaptation of plant RT vascular wilt pathogens."; RL PLoS Pathog. 7:E1002137-E1002137(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS572715; EGY18184.1; -; Genomic_DNA. DR EnsemblFungi; EGY18184; EGY18184; VDAG_08518. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1098 AA; 124255 MW; E1C1C85E0ED4DB73 CRC64; MEMPDGTTDI VHPEVRAHIN SLVSALGGIS ADDDGRYNLG DDALEVLRDL KKWIRFYDEK TNRMDVARCI AEANLIDGDL LPILATWPEN STDNKFRSRI ALACFEIMVP LTWPMERDPE QTTVNHHRHM PALQLAQVGY KRSIINFDGA RILHAAARVA LPAMAAPIGE RTPRDQGIIK LVLFFLRNVA MIEPQPNVKY EGEESQISRS ATIDAFSYQD IFMVLLTIAS NMGEDFRTED VTIMEIIYHL VKRVDVKKLF MSEQQVNKAK ADELSVMMGK ENAMLKAQNR KGPTRHNRFG TVIWVKRADG KMTAVSGQEA LVDVASRRKK MDETKKFRPP AKARSKTDSH MKDLGELPKL DARAYSQLRS FVEEFLDAGF NPLFEHVRKS IDREASHVLS YHRRQFLYLV AWFLEAERTR KSSQRASAPK NSAEEVSSFN LVAAVLNQST FITLNRTMTQ AWEHKDWPEL TASMRCLTQI LLTVQEMSHS PNEDDQEIAE NTLSRLFYED AMHDLIANVV RQYKEQGFDY LDAATELTHH FLRILEAYSK QNVDMQVRSR RRTRRKKKAA KEASADGEGD EDEADDSGDD EKNAELTIKE RKFDFRRFSA RFTPQGVVDT FVAFTKFYKD LSDEQLKRAH RYFYRVAFKH DASVMLFRVD IVHLLHEMVK GPEPLDKASS MYKEWEELAK QILRKCFKKI DERPALLIEM LFSKISSTAH YLEYGFEKQT ISTSRPRPAA DLEFKYTEDR EQQIAIAVGV LLDKSQSDHI AWVKTILTNA EQERRALAAA EDILPSVEAT GDHDEPVDKP ADSFMPYTAR PDNDARQAAM FKNPHLRLLM RLAGLERLAP TLDESPDSLW VVPASATPDQ LRETLDLINK AEFSPPVFEE GVLAEHQLRR KTATRKKAQR SVCASAAARD PAASGSDDDD DDDAARARAR ARRERERAKL EKIKSQLYVA ASDDETDDER DAAFFAREEA QRTRMARAAA AGVDVSEVAV PAARKEPQSI AVGDDDDDDV LLADIHGAGT DEENEDGNGE EASASSSQEG RKRKGSGVVD ADGDVEMDDE DEDDLPVPSA RPRKRIKGGF VMESSDEE // ID G3AP37_SPAPN Unreviewed; 1152 AA. AC G3AP37; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 09-JUL-2014, entry version 5. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=SPAPADRAFT_50663; OS Spathaspora passalidarum (strain NRRL Y-27907 / 11-Y1). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Spathaspora. OX NCBI_TaxID=619300; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NRRL Y-27907 / 11-Y1; RX PubMed=21788494; DOI=10.1073/pnas.1103039108; RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., RA Labutti K.M., Sun H., Clum A., Pangilinan J.L., Lindquist E.A., RA Lucas S., Lapidus A., Jin M., Gunawan C., Balan V., Dale B.E., RA Jeffries T.W., Zinkel R., Barry K.W., Grigoriev I.V., Gasch A.P.; RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel RT production."; RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL996502; EGW32068.1; -; Genomic_DNA. DR RefSeq; XP_007375344.1; XM_007375282.1. DR GeneID; 18871469; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1152 AA; 130933 MW; D3022076CC9019F1 CRC64; MSSSSDSETY EELGDFIVDE EPIQESNSQD ESNEPDLAND RIRSLTTTLQ PNQTPAQKLL RAHIAVLCSA LGGPDHTSNI TPPPYKLGHD ALACLKDIKR WIRAVDERQN NYAVALACAD SGLVKDLIVI MCQFDKKKTG IKVEKIRLAC LELLVLLTWP VEFGAELSES QRLLFTEVRK VQVGYKKLIL SYLNGAVLKS VIRLVLPVIK KSRLDREPRE NQILKLVLYL VRNVVAIVPA NASVSSKSSH RAVVVADDLP NGVSADDISI NNVVSVFEKN KVLMLLLTIS GSIGTEFDKD MFGEICLECI YLLVKGLSVS ELLEKPTPKD PTNPSQPLQS VSTTAGMELQ DLLASETKRK QSQTATVSTR HGRFGSLLSI KAPDSNPYVV SGQEALFTTS STLTKLDKSK TWKNRTLFKY DSDEYVISRY PVYLTTTGRN ILHEFVKSFL SGGCFNNLIE TMSSRLTTIS DMTVVDEYTK ASYFFTISWF LSYEKQSIKL QQAQDYGSVG AALSSVNFIL LTSYFRDSFG SKSWNSLHVA MLCFRELIQI SNSLFGKQDA DETDRDLAEG IIRKLFSFSD FVNIIAQIPQ TAAKHSPAYL GVVVSVVNTL LESFETFANE DVELYIQSRR KKSKSKRNTE RHPEALQDVI DASDDEQDAA TAKEITKERK LDFKLTEARF FHTSIVNAYI AYLSRYDDLD ASQIKICFKY FHRLFVVRKD FTGLYRLDFM QLLERLHHDL RGSSRARVDE FIYYFMKKFK IALERFPMPI ELLFPRMEDL SCKIYLATGE LYTKPEPNTR GPRLAKQLEF VRDFNRDEQV KILVSALKRE DKLALLVWII SELERILSER ILDDSSIAEL NPGVHRRLFI NNGNLRLLLK LIGFDLPFTM DENPELPTSV ETATLTEFID LIKKWKDQHG EFDDGKEPSF FLRAREDDEE EDYGEGDDIA FETAPGSGER MNIHELDALD ELEQSLSQRS KGHARKKRPQ RVHEHHRTSG ERQRLPPVTR TFNSAEFVHD SDDESDDEKD AEFFAREERL RTLLGESGGI VDGRQLAEFK LRWAEIEKNG GVLPERRVDT SELFVNDDDD DDDDIMSDAP QSSTDSSKRS ADEEEEEERQ EVAPAKRLAD DDDEEIAHVK RKRIVVSDDE DE // ID G3B6I2_CANTC Unreviewed; 1245 AA. AC G3B6I2; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 6. DE SubName: Full=Timeless-domain-containing protein; GN ORFNames=CANTEDRAFT_130920; OS Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / OS NBRC 10315 / NRRL Y-1498 / VKM Y-70) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=590646; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / RC NRRL Y-1498 / VKM Y-70; RX PubMed=21788494; DOI=10.1073/pnas.1103039108; RA Wohlbach D.J., Kuo A., Sato T.K., Potts K.M., Salamov A.A., RA Labutti K.M., Sun H., Clum A., Pangilinan J.L., Lindquist E.A., RA Lucas S., Lapidus A., Jin M., Gunawan C., Balan V., Dale B.E., RA Jeffries T.W., Zinkel R., Barry K.W., Grigoriev I.V., Gasch A.P.; RT "Comparative genomics of xylose-fermenting fungi for enhanced biofuel RT production."; RL Proc. Natl. Acad. Sci. U.S.A. 108:13212-13217(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL996524; EGV63474.1; -; Genomic_DNA. DR RefSeq; XP_006687267.1; XM_006687204.1. DR GeneID; 18249487; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1245 AA; 142542 MW; 4D843BFB98B56906 CRC64; MREMASVLKP NENHTQKILK AHVSVLVSAL GGPDYTSSNV PQPYKLGHDA LACLKDIKRW IKSVDERGQS YDVALACADS GLLVNDLTVM LCQWDSQASK GEPIKNARTM EKIMLANLEL LVLLTWPTEL TPESSESQRL SFSNLRKTQL VYKRHILHYN KGQTLKAVIR LVLATMAKEK ADREPKDNAI LRLVLFFIRN ILYIAPITSS ISMKTTKDLA SLDSMPAGVT TEDISMSTVL NCFKRNKVLM FLLTMSNSVG SDFDKQMFGP ACLECIYLLV KNIQVEHIIS PVKLDKHPQT NPAPVSSESA AGSQLTDLLK EETKRKISQK QHLSTRHGRF GSLLSIQGDE QSYVISGQEA LLNANSSLDK LDRSKKWTKP KSFRYDSDEF TRGERLYLNT GSILILKEFI NQFLAGACFN NLISNTSSLF SSADDLITID PYERAVYFLT LAWFLRYKRE RNQLLKDNPK MLENLTDDDD SVNFSSIRAA LSQTNFILIL HYFRNSYTIK EWSSVHVAMI AFLELLLISH TLFISKPKEV EADEEESQEE LDKELGEGII RNLFTSNDFL NVLVQLPQSA SKHSPEYLKT CIHIVHILLK SFESFTKENV KLYIQKRRRK VKRRGEGAND MDGRILHRLE ERGMGYSEDE EADEERAKEE KIERELDLAK TEIRFFHTAT VTSYIDYLAE YEELTHEEIK RCLSYFHRLF VVKKDHSALY RLDFMYVLHR LRSYLPRSSS MRNHVDEFIV YFMKKFKVAF ARFPNPIEIL FPRFEEHEIK TFLTTGELTS RYSESKSQPK LARQIDFIRE FSFEEKVKIL ITALYLEEKE AFIAWLISAL DAIIQKRLLD VASGSTEDAR AISLQAPDKF RRLLINNPQI RCLLTLVKFD LPDILEENCE IPGSVTSAKL VEFLEFIKKY IAAQPVNFED GKDAFFFLIT KDSYGYDDDY DINYRGYDPE DESIAFETAG NQEKSHYMEE LDQLDRLEAS ISSVGHGQLG VARKKRKEKA NKPPKKSSRA PKETGPRGSR PRQPVALPQH FTKSAEFIND SDDDSDEEKD EEFFAREEKL RRLLSESGGI VNSTQLEDFK KVWKILATDT DKDLETSVNK AVANATDNLR ASQHQQSQDL FGSFSDTQTQ TQTQTQFSND DENNVNNSTR LSYSSESDLS SDEETLTNDV DESLTRDENK ENETPTGTQV NPRKRPMVFS DNESDDENVS FVSASGDVSL RKRKIVLDDD DDDDE // ID G3HRN7_CRIGR Unreviewed; 1200 AA. AC G3HRN7; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 03-SEP-2014, entry version 7. DE SubName: Full=Protein timeless-like; GN ORFNames=I79_013483; OS Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Cricetidae; Cricetinae; Cricetulus. OX NCBI_TaxID=10029; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21804562; DOI=10.1038/nbt.1932; RA Xu X., Nagarajan H., Lewis N.E., Pan S., Cai Z., Liu X., Chen W., RA Xie M., Wang W., Hammond S., Andersen M.R., Neff N., Passarelli B., RA Koh W., Fan H.C., Wang J., Gui Y., Lee K.H., Betenbaugh M.J., RA Quake S.R., Famili I., Palsson B.O., Wang J.; RT "The genomic sequence of the Chinese hamster ovary (CHO)-K1 cell RT line."; RL Nat. Biotechnol. 29:735-741(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JH000638; EGW12497.1; -; Genomic_DNA. DR RefSeq; XP_007644858.1; XM_007646668.1. DR GeneID; 100764475; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1200 AA; 138113 MW; 275D68C70B287C1C CRC64; MNCELLATCS ALGYLEGDTY HKEPDCLESV KDLIRYLRHE DETRDVRQQL GAAQILQSDL LPILTQHRQD KPLFDAVIRL MVNLTQPALL CFGGVPKDPG VRHHFLQVLT HLQAYKEAFA SEKTFGVLSE TLYELLQLGW EDRQEEDNLL IERILLLVRN ILHVPADLEQ EKRIDDDASI HDRLLWAIHL SGMDDLLLFL SSSSAEQQWS LHVLEIVSLM FRDQNPEQLA GVGQGRLAQE RSTDMAELEV LRQREMAEKR TRALQRGNRH SRFGGSYIVQ GLKSIGERDV IFHKGLHNLR NYSSDLGKQP RRVPKSRQAA QELSVHRRSA LNVRLFLRDF CSEFLENCYN PLMGAVKDHL LRERAQQHDE TYYMWALAFF MAFNRAASFR PGFVSETLSV RTFHFVEQNL TNYYEMMLTD RKEAASWARR MHLALKAYQE LLATVNEMDI CPDEAVRESS RIIKNNIFYM MEYRELFLAL FRKFDERYHP RSFLRDLVET THLFLKMLER FCRSRGNLMV QNKRKKRKKK KKKVQDQSVA SDHVSHSPGE LEALWPALEE QLLRCAQDPE LSTDSIIPFD AASEVPVEEQ RVEAMVRIQD CLLDGQAPQA LALLRSAREV WPEGNVFGSP VTSPGEEMQL LKQILVAPLP RQQEPIEGDA EEEEEEEEEE EELQVAQVSE KEFNFLDYLK RFACSSIVRA YMLLLRSYRQ NSAHTNHCVA KMLHRLAHDL GMEALLFQLS LFCLFNRLLS DPAAGAYKEL VTFAKYILGK FFALAAVNQK AFVELLFWKN TAVVREMTQG YGSLDSGSSS HRATAWSPEE EAQLQELYLA HKDVEGQDVV GTILAHLKTV PRTRRQVIHH LVRMGLADSV KDFQRKGTQI VLWTEDQELE LQRLFEEFQD SDDVLGHIMK NITAKRSRAR IVDKLLALGL VSERRQLYKK RRKKVAPSCT PNGGVSLKDP WQEDTEEEEE HLPEEEEEEE EDLEAEPVHS SSFLSAGNLG QSLHQEGLSA PLLWLQNCLV RAADDRQEGG CSQAIPLVPL TEENEDAMEN EQFQNLLRKL GIRPPTPGQE TFWRIPAKWS SIQLRRVAAA LSQQEEEEER EEEPELHPGA PGEHRPDEEH RAKALRALLS ARKRKAGQMS PEVTSEEETT GEKEWKRVSK KRELLDSDEE EDEGRGQASE LGTPVIHKKK RFQIQDDDDD // ID G3J948_CORMM Unreviewed; 1162 AA. AC G3J948; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 6. DE SubName: Full=Drug resistance protein MdrA; GN ORFNames=CCM_03148; OS Cordyceps militaris (strain CM01) (Caterpillar fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Cordycipitaceae; OC Cordyceps. OX NCBI_TaxID=983644; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CM01; RX PubMed=22112802; DOI=10.1186/gb-2011-12-11-r116; RA Zheng P., Xia Y., Xiao G., Xiong C., Hu X., Zhang S., Zheng H., RA Huang Y., Zhou Y., Wang S., Zhao G.P., Liu X., St Leger R.J., Wang C.; RT "Genome sequence of the insect pathogenic fungus Cordyceps militaris, RT a valued traditional chinese medicine."; RL Genome Biol. 12:R116-R116(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JH126400; EGX94877.1; -; Genomic_DNA. DR RefSeq; XP_006668363.1; XM_006668300.1. DR GeneID; 18165175; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1162 AA; 132537 MW; 970622418FF42213 CRC64; MDLPDGGHDI VHPEVRAHIT SLISALGGIS TDEEGQYQLG DDALEVLRDI KRWIRFYDEK TNRMDVARCV YEGNLVLGDL IPIIAKWPEE SMDNKFKSRI VLSCFEVMVP LTWPIDQDKE KMTVNHHRHV PILELAQLQY KSAIINFDGA RILHSAIRSA LPSMAVPIGD RTPRDQGVIK LILFLLRNMA MIAPSPGVKF DGDEGHISRS TTIDAFSYQD VFIVLLTIAS NMGEDFRTED ATVMEIIYHL VKQVDVEKLF MDEDQISKAM AGELSDLMKK ESAQQQAGNR KGPTRHNRFG TMVWVKREDG KMTSLSGQDA LADAVTRSKK MDASKIFRPT RRSRKANKEE KDLGLPTPLT PGAVKQLRSF VEEFLDSGFN PLFLHIRKSI DREAPHIMEF HRRQFFYLIA WFLDAERVRR QRSKANNKKR AEEVSSFNLI ASVLNQEMFI TLSKGLHESY DYKDWPSLSA AMRCFTQILL TIQEMAEEGT DDDQEIAENV LSRLFYEEST HDIIANIART YKDQGFEYLD AATELVHHFL RVLEAYSKQN ADMQVRSRKR ARRKKKAETQ QSGVDDEEND ESGQDEAAVE RTSKERKFDF HRFTSRFTPQ GVVNTFIAFT KYYRELNKMQ LKRAHRYFYR LAFKQDMGVM IFRVDMLHML LNMVNGPDAL DRSSKMFKDW EELIKQLFRK CFKKMQERPE LIVEMLFSKL PATAFFLEYG YEKQTSVVKA QPRPAAELVF KHTTEHDQQV GITVGALLDK NDSDHLEWFK NVLTTAEIER RSWSNANDEL LATETPVDDA EMAEMPQEPR LPPVITVRPD SPDRRSAMFK NPYLRLLMNL VGVRLLGPAT EETPESVWII PSEVTANQLK DALHYINQAE FNPPTFEDGT SAEQQLKRKT VPRKKAAFDD DNADDEDGLD DFLDDPMMFP AGGPTARKVV DETKKSQKSK KSRKRRSASE EIDDPEREDR ARKRRDKERE KARKIKSALY VKDGDDDFDS DEDEEFFARE RAIKTRAEQA ARSAMRGFAD DDSIAPGQPA AKPRSQALFD DGTDDEDGVD NVNSAHRILS SQSTVDASET HETELGGGGA ERQKRRRLSP RTDDDEDMGM GDADVEERIT SGTVLALDGG SSAEEEDTAA PTSTARKSRV RGGFVIDSDD DE // ID G3N5Y5_GASAC Unreviewed; 1143 AA. AC G3N5Y5; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 11-JUN-2014, entry version 8. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; OS Gasterosteus aculeatus (Three-spined stickleback). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Perciformes; Cottioidei; Gasterosteales; OC Gasterosteidae; Gasterosteus. OX NCBI_TaxID=69293; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lindblad-Toh K., Mauceli E., Grabherr M., Chang J.L., Lander E.S.; RL Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSGACT00000000709; ENSGACP00000000709; ENSGACG00000000545. DR GeneTree; ENSGT00390000015124; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1143 AA; 133259 MW; BFC31E7995742590 CRC64; EKSSRMNCEL LATCSALGYL EGDTYHKEAD CLESVKDLIR FLRHEDDTRD IRQQLGAGQI VQNDLLPIII QHGQDKALFD ACIRLMVNLT QPAMLCFGKV PDDPVFRHHF LLVTSHLQAY KEEFAGEAVF GILSETLYTL LQLDWEQRQE EDNLLIERIL LLVRNVLHVP ADPCEEKKVD DDASIHDRLL WAIHMSGFDD LIKFLASAQS EQQWSMHVLE IISLMFRDQT PEGLVSAGHA RSAEEKHRDT LELEALRQKE LATKRSRTLQ RGTRHSRFGG SYVVEGLKSI GDRDVIYHRN VHHFKNYTHD TGKAVRRVPK RNRQARECKD QRRSALNVRL FLREFCVDFL ENCYNRLMYL VKESLIREQT QQHDETYYLW ALSFFMAFNR GNGFRADLVS ETMSIRAFHY IERNITNYYE MMLTDRKEAT SWSRRMHLAL KAYQELLLTV NEMDRSQDES IRQSSSVIKS NIFYLMEYRE IFLTLLRKYD ETRQPHSYLI DLVESTHLFL RMLERFCKGR RSLMVQKKKV RRRRSRGKKK PSSPETSPEA LVETWKIVEE ELRASAFQLS ESLTENTVPF DATSETPLED QKTEAMVRVQ DALLSRLAPE ALGLLRAARE VWPEGDVFGS ADVEPEEELE LLKQILHANL PSMFWSSPPE PAEEEDEDAA ELEEDELESV QISEKEFNFL DFIKRFSNPS VVRPYLHLLK SYSKNTPHTN HCIARMLHRL AVDLKMEAQI FQLSVFNLFN KILSDPAAAA YKELVTFAKF VLNRFFSLAA QNNKAYVELL FWKNVGAVRE MTEGYGIDRL VHETKPSWTE VEEEELRNLY EEHRHSEGPD IVETLLPLLS NSNRTRRHVV MQLVHMGLVE NAKALKKPKK GTQIVLWTEE QEEELQMLYE EYKDSDDVLG NLLKKLTAKR SRARVVDKLL SMGLVSERRQ LYKKRKELTQ GLLDDFGDRD EEEDESEEES EEEKDEAQES ETQHVTRRSR SLPSTEERGP DVGSTVYALQ QEGLSGPLLW LQNSLYKTAM YRDDDGFSQD VPFVPFGEEN ADAMENKTFR RLLRKLGLRP PANEQETFWR IPAEISDSQL KSAAAALRPR DENERKKEER KKEERKKEKE EGEVSVEHRV QALRAVRLKR QRK // ID G3RK99_GORGO Unreviewed; 1179 AA. AC G3RK99; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 14. DE SubName: Full=Uncharacterized protein; OS Gorilla gorilla gorilla (Lowland gorilla). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Gorilla. OX NCBI_TaxID=9595; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Scally A.; RT "Insights into the evolution of the great apes provided by the gorilla RT genome."; RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSGGOT00000016619; ENSGGOP00000016161; ENSGGOG00000016556. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1179 AA; 135338 MW; B74CC08B05FE3F29 CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHHQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADF AELEVLRQRE MAEKKTRALQ RGNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDISPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKQK KRRKKKKKVL DQAIVSGNVP SSPEEVEAVW PALAEQLQCC AQNSELSMDS VVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQALTLLR SAREVWPEGD VFGSQDISPE EEIQLLKQIL SAPLPRQQGP EERGAEEEEE EEEEEEEEEL QVVQVSEKEF NFLDYLKRFA CSTVVRAYVL LLRSYQQNSA HTNHCIVKML HRLAHDLKME ALLFQLSVFC LFNRLLSDPA AGAYKELVTF AKYILGKFFA LAAVNQKAFV ELLFWKNTAV VREMTEGYGS LDDRSSSRRA PTWSPKEEAH LRELYLANKD VEGQDVVEAI LAHLNTVPRT RKQIIHHLVQ MGLADSVKDF QRKGTHIVLW TGDQELELQR LFEEFRDSDD VLGHIMKNIT AKRSRARIVD KLLALGLVAE RRELYKKRRK KLASSILPNG AESLKDFCQE DLEEEENLPE EDSEEEEEGG SEAEQVQGSL VLSNENLGQS LHQEGFSIPL LWLQNCLIRA ADDREEDGCS QAVPLVPLTE ENEEAMENEQ FQQLLRKLGV RPPASGQETF WRIPAKLSPT QLRRVAASLS QPEEEQKLQP ELQPKVPGEQ GSDEEHCKEH RAQALRALVL AHTKKAGLAS PEEEDAIGKG PLKAAPKKRQ LLDSDEEQEE DEGRNRAPEL GAPGIQKKKR YQIEDDEDD // ID G3S3K4_GORGO Unreviewed; 868 AA. AC G3S3K4; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 18-SEP-2013, entry version 8. DE SubName: Full=Uncharacterized protein; OS Gorilla gorilla gorilla (Lowland gorilla). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Gorilla. OX NCBI_TaxID=9595; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Scally A.; RT "Insights into the evolution of the great apes provided by the gorilla RT genome."; RL Submitted (MAY-2011) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSGGOT00000022053; ENSGGOP00000022654; ENSGGOG00000016556. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 868 AA; 98616 MW; 34ADF206A0C4BDAF CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLVSEESVKD LIRYLRHEDE TRDVRQQLGA AQILQSDLLP ILTQHHQDKP LFDAVIRLMV NLTQPALLCF GNLPKEPSFR HHFLQVLTYL QAYKEAFASE KAFGVLSETL YELLQLGWEE RQEEDNLLIE RILLLVRNIL HVPADLDQEK KIDDDASAHD QLLWAIHLSG LDDLLLFLAS SSAEQQWSLH VLEIVSLMFR DQNPEQLAGV GQGRLAQERS ADFAELEVLR QREMAEKKTR ALQRGNRQVL FPTSWNAEGI EGKFPTFQEK KLEAFQLISF VIEKTLMGSL DILIQFFPHR TNILDQAIVS GNVPSSPEEV EAVWPALAEQ LQCCAQNSEL SMDSVVPFDA ASEVPVEEQR AEAMVRIQDC LLAGQAPQAL TLLRSAREVW PEGDVFGSQD ISPEEEIQLL KQILSAPLPR ESPPFTSVSF QRQQGPEERG LQVVQVSEKE FNFLDYLKRF ACSTVVRAYV LLLRSYQQNS AHTNHCIVKM LHRLAHDLKM EALLFQLSVF CLFNRLLSDP AAGAYKELVT FAKYILGKFF ALAAVNQKAF VELLFWKNTA VVREMTEGYG SLDDRSSSRR APTWSPKEEA HLRELYLANK DVEGQDVVEA ILAHLNTVPR TRKQIIHHLV QMGLADSVKD FQRKGTHIVL WTGDQELELQ RLFEEFRDSD DVLGHIMKNI TAKRSRARIV DKLLALGLVA ERRELYKKRR KKLASSILPN GAESLKDFCQ EDLEEEENLP EEDSEEEEEG GSEAEQVQGS LVLSNENLGQ SLHQEGFSIP LLWLQNCLIR AADDREEDGC SQAVPLVPLT EENEEAMENE QFQQLLRKLG VRPPASGQ // ID G3SUV3_LOXAF Unreviewed; 1199 AA. AC G3SUV3; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 15. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Loxodonta africana (African elephant). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta. OX NCBI_TaxID=9785; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Isolate ISIS603380; RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., RA Lindblad-Toh K.; RT "The Genome Sequence of Loxodonta africana (African elephant)."; RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RC STRAIN=Isolate ISIS603380; RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSLAFT00000004745; ENSLAFP00000003969; ENSLAFG00000004742. DR GeneTree; ENSGT00390000015124; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1199 AA; 137465 MW; 0B5476D4012024D2 CRC64; VDLYMMNCEL LATCGALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLTYLQAY KETFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADPDQEKSID DDASVHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IISLMFRDQN PEQLAGVGQG HLAQERSTDV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDVIFHKG LHNLQNYSSD MGKQRRRVPK RRQAAQELST QRSALNVRLF LRDFCSEFLE SYTRLMGSVK DHLLREKAQQ HDETYYMWAL AFFMAFNRAA TFRPGLVSET LSVRTFHFVE QNLTNYYEMM LTDRKEAVSW ARRMHLALKA YQELLATVNE MDTSSDEAVR ESSRIIKNNI FYVMEYRELF LALFRKFDER CQPRSFLRDL VETTHLFLKM LERFCRSRGN LVVQNKRKKR KKKKKALDQP SASNNIPCSL EELEATWPAL AEQLLCYGQA PQLSLDSVVP FDAASEVPVE EQRAEAMVRI QDCLLAGQAP QALSLLRSAR GSQSSKERHS IGILGVNIEQ WVLGRVLIGL LVVVFENDQK AQLIRKKWQQ GQLQVVQVSE KEFNFLDYLR RFACSTVVRA YVLLMRSYKQ NSAHTNHCVV KMLHRLAHDL KMEALLFQLS LFCLFNRLLS DPAAGAYKEL VTFARYILAK FFALTAVNQK AFVELLFWKN TAVVREMTEG YGSLDGGSSS RRPPMWSPEE EAQLRELYLA HKDVEARGQD VVDAILAHLP TAPRTRKQII HQLVRLGLAD SVKDFQRKGT HIVLWTEDQE LELQRLFEEF QDSDDVLGHI MKNITAKRSR ARIVDKLMAL GLVTERRELY KKRRKKLAPS SSPNGEESLK NFCKEDTEED NLSEEKSEEE EEEDLGADQA QGSSVLPTED LGQNLHQEGF SAPLLWLQNC LIRVADDREE DGCSQSVPLV PLTEENEEAM ENEQFQQLLS KLGVQPPASG QETFWRIPAK LSPTHLRRLA ASLSQRKEEE KLQPELELEI HGEQGPGEEH RAQALRALLL ARKKKAGLAS PEEEGATDGK EQLKAAPKKR QLLDSDEEQE EDEGRSKAPE VGAPGIQKKK RFHIEDEDE // ID G3U4J9_LOXAF Unreviewed; 1193 AA. AC G3U4J9; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 16-APR-2014, entry version 7. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Loxodonta africana (African elephant). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Afrotheria; Proboscidea; Elephantidae; Loxodonta. OX NCBI_TaxID=9785; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Isolate ISIS603380; RA Di Palma F., Heiman D., Young S., Johnson J., Lander E.S., RA Lindblad-Toh K.; RT "The Genome Sequence of Loxodonta africana (African elephant)."; RL Submitted (JUN-2009) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RC STRAIN=Isolate ISIS603380; RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSLAFT00000032820; ENSLAFP00000022757; ENSLAFG00000004742. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1193 AA; 136714 MW; DEDAC6F451A1B287 CRC64; VDLYMMNCEL LATCGALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLTYLQAY KETFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADPDQEKSID DDASVHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IISLMFRDQN PEQLAGVGQG HLAQERSTDV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDVIFHKG LHNLQNYSSD MGKQRRRVPK RRQAAQELST QRSALNVRLF LRDFCSEFLE SYTRLMGSVK DHLLREKAQQ HDETYYMWAL AFFMAFNRAA TFRPGLVSET LSVRTFHFVE QNLTNYYEMM LTDRKEAVSW ARRMHLALKA YQELLATVNE MDTSSDEAVR ESSRIIKNNI FYVMEYRELF LALFRKFDER CQPRSFLRDL VETTHLFLKM LERFCRSRGN LVVQNKRKKR KKKKKALDQP SASNNIPCSL EELEATWPAL AEQLLCYGQA PQLSLDSVVP FDAASEVPVE EQRAEAMVRI QDCLLAGQAP QALSLLRSAR SWAFGVGRTS HSVGPGESFD WFVVIPTFSI GQQGPEEQGA EEEDEEEEEE EELQVVQVSE KEFNFLDYLR RFACSTVVRA YVLLMRSYKQ NSAHTNHCVV KMLHRLAHDL KMEALLFQLS LFCLFNRLLS DPAAGAYKEL VTFARYILAK FFALTAVNQK AFVELLFWKN TAVVREMTEG YGSLDGGSSS RRPPMWSPEE EAQLRELYLA HKDVEGQDVV DAILAHLPTA PRTRKQIIHQ LVRLGLADSV KDFQRKGTHI VLWTEDQELE LQRLFEEFQD SDDVLGHIMK NITAKRSRAR IVDKLMALGL VTERRELYKK RRKKLAPSSS PNGEESLKNF CKEDTEEDNL SEEKSEEEEE EDLGADQAQG SSVLPTEDLG QNLHQEGFSA PLLWLQNCLI RVADDREEDG CSQSVPLVPL TEENEEAMEN EQFQQLLSKL GVQPPASGQE TFWRIPAKLS PTHLRRLAAS LSQRKEEEKL QPELELEIHG EQGPGEEHRA QALRALLLAR KKKAGLASPE GATDGKEQLK AAPKKRQLLD SDEEQEEDEG RSKEVGAPGI QKKKRFHIED EDE // ID G3VBC7_SARHA Unreviewed; 1202 AA. AC G3VBC7; DT 16-NOV-2011, integrated into UniProtKB/TrEMBL. DT 16-NOV-2011, sequence version 1. DT 14-MAY-2014, entry version 10. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Sarcophilus harrisii (Tasmanian devil) (Sarcophilus laniarius). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Metatheria; Dasyuromorphia; Dasyuridae; Sarcophilus. OX NCBI_TaxID=9305; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=21709235; DOI=10.1073/pnas.1102838108; RA Miller W., Hayes V.M., Ratan A., Petersen D.C., Wittekindt N.E., RA Miller J., Walenz B., Knight J., Qi J., Zhao F., Wang Q., RA Bedoya-Reina O.C., Katiyar N., Tomsho L.P., Kasson L.M., Hardie R.A., RA Woodbridge P., Tindall E.A., Bertelsen M.F., Dixon D., Pyecroft S., RA Helgen K.M., Lesk A.M., Pringle T.H., Patterson N., Zhang Y., RA Kreiss A., Woods G.M., Jones M.E., Schuster S.C.; RT "Genetic diversity and population structure of the endangered RT marsupial Sarcophilus harrisii (Tasmanian devil)."; RL Proc. Natl. Acad. Sci. U.S.A. 108:12348-12353(2011). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (SEP-2011) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AEFK01189682; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSSHAT00000000488; ENSSHAP00000000481; ENSSHAG00000000431. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1202 AA; 138788 MW; A5F20AE9CE71FE43 CRC64; VDLHMMNCEL LATCSALGYL EGDIYHKEPD CLESVKDLIR YLKYEDETHD VRQQLGAAQI LQGDLLPILI QHRQDKPLFD AVIRLMVNLT QPALLCFGKV PQDPSFRHHF LQVLSYLQAY KEAFANEKVF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADPDQEKNVD DEASVHDQLL WALHLSGFDD LMLFLASSAS EQQWSLHVVE IVSLMFRDQN PEQLAVAGQA RSAREQGADM AELEILRQRE MAEKKNRALQ RSSRHSRFGG SYVIQGLKSI GDRDVVFHKS LHNFQSYSPD VGKDTRYVPR RRQLAQEPTF QRRSALNVRL FLRDFCSEFL ENCYNRLMGL VKDHLLREKA QQHDETYYLW ALAFFMTFNR ASNFRPSLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAV SWGRRMHLAL KAYQELLATV NKMDTSEDEA VRESSRIIKN NVFYIMEYRE LFLTLFRKFD ETRQPRSYLR DLVETTHLFL KMLERFCRSR GNLIVQNKRR RRKKKKKAPT QSPAAAGQVP YRPEDAEDVW PSLAEQLKHC AQNSELTLDS VVPFDAASEV PVEEQRTEAM VRIQDSLLSS QAAEALALLR SAREVWPEGD IFGSPDFSLD EEIELLRQIF SAPLPRQQEP EEQGGEEEEE EEEEEEEELQ AVQVLEKEFN FLDYLRRFAC SAVVKAYVLL LQSYQKNTPH TNHCVVKMLH RLAHDLKMEA LLFQISLFSI FNRIFSDPAS GAYKELVTFA RYVLAKFFAL TEVNRKAFVE LLFWKNTAVV REMTEGYGSL DAESSNRKPS KWSPEEEKQL QELYLAYKDI EGEDVIDAIL TRLTTTTHSR KQVIQKLVGL GLADSVKDFQ RQRKGTRLVL WTEEQELELQ RLFEEFQGSD DVLGHIMKNI TAKRSRARIV EKILSLGLVA ERRELYKKRR RKPATTSLLD GKDPLTDPDQ EDPEEEEEED PLLEEDSEED EEGPGAEAAQ NTRGHISQSL RQILQEEDFS APIQWLQNCL IRIAEDREVD GCSQAVPLVP LTEENEDAME NRDFQKLLRK LGIRPPASEQ ESFWRVPAKL SPALLRRAAA SLSQARPEIQ SAECPEQGPR KEKPAQVPGS PVTAKKRKVA LEVISEGKAE EEPSSSGSQK LQLLDSDGEQ KDENESKDTD PDSPEPPRIH KRRRFLIEDE DD // ID G3XN97_ASPNA Unreviewed; 1108 AA. AC G3XN97; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 11-DEC-2013, entry version 6. DE SubName: Full=Uncharacterized protein; GN ORFNames=ASPNIDRAFT_41490; OS Aspergillus niger (strain ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB OS Ac4 / NCTC 3858a / NRRL 328 / USDA 3528.7). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=380704; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 1015 / CBS 113.46 / FGSC A1144 / LSHB Ac4 / NCTC 3858a / RC NRRL 328 / USDA 3528.7; RX PubMed=21543515; DOI=10.1101/gr.112169.110; RA Andersen M.R., Salazar M.P., Schaap P.J., van de Vondervoort P.J.I., RA Culley D., Thykaer J., Frisvad J.C., Nielsen K.F., Albang R., RA Albermann K., Berka R.M., Braus G.H., Braus-Stromeyer S.A., RA Corrochano L.M., Dai Z., van Dijck P.W.M., Hofmann G., Lasure L.L., RA Magnuson J.K., Menke H., Meijer M., Meijer S.L., Nielsen J.B., RA Nielsen M.L., van Ooyen A.J.J., Pel H.J., Poulsen L., Samson R.A., RA Stam H., Tsang A., van den Brink J.M., Atkins A., Aerts A., RA Shapiro H., Pangilinan J., Salamov A., Lou Y., Lindquist E., Lucas S., RA Grimwood J., Grigoriev I.V., Kubicek C.P., Martinez D., RA van Peij N.N.M.E., Roubos J.A., Nielsen J., Baker S.E.; RT "Comparative genomics of citric-acid-producing Aspergillus niger ATCC RT 1015 versus enzyme-producing CBS 513.88."; RL Genome Res. 21:885-897(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ACJE01000002; EHA27554.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1108 AA; 127841 MW; 3F12423D9560BAF7 CRC64; MENEEPVLSA PDVQVVDPDV RAHVYSLVTA LGGFNGEDAD KYVLGDDALA CLRDIKRWLK LYDEKHNRMD VARCLGEANL VNGDLLPILA VWANSKKQTK YMSRIALACL ELLVPLTWPV ELHGELTINH HRHIPYIQHV HVSYKRGLLS HASTSYLRTI IRVGIPSMAI PRSERTTRDE GILKLLLYLL RNIALITPNT RLAAEGDEEE TSRSATINAF QDQDVFALLL TMCSNVGDDF TMQDVALLEI LFHLIRGVSV EKLFMDDAQR TAKRTDELDD LLRQESSLRR EYAKNAPTRH GRFGTMIWVK RDDAKYSTVS GQNVLKDGQA TLQKMDETKK WNKPLIRRKP QDLTVHNDFS TPVHLNSTAS NNLRMFVEEF LDSGFNPLLT HVRKAIEREA DRVMDINTRQ FLYTTAWFLE AERARRARQR KKHAESEKPA KELEPDSFGL VAGVLNQETF VFLNRAMQYA LDNKDWEDLN AGMRCFTQIL LTVQDMAQSP LEEDQEIAEN IQNRIFYEET THDRVLAVIR GYKDQPFGYL DACTELTHVF LRMLERYSKE NLDMQVRSRR RARRKAKDVE GTGNDENDEE NGSEDEDRLE AERVSKERKF DFRRFAAKFC NQKCVDTFVA FTKHYKELNT EQLKRAHRYF YRIAFKQELS VLLFRLDIIN LFYRMIKGPG ALDSSKPIFK EWEEFVRQII RRLTKRLDQR PVLFVELLFS KINATTFYLE YGHERQTVTR ARKAPAELEI DPRQAHTIEE KISIMVPALV LDGEEDLVTW VSDVLESAVE EREAWETQEK ALRDAGDLRE MKSFIDKYFE KAKRGTLGRD PRELIRRKYG GGKTASDNQH NPDIQFGDDS EGEDEVPDGP LFPPNPRAAP NPANKPTKKK KRKERNPDDE DEDDSVDEET LEERRRARLE NSRARLAKIK SDLYVHASDE DTDEEGDKEF FLLEEQRRRE QAKRIKHALL TGMTEDGDGS TNKKGQRKRQ TTRNRTGEAK SKRQRRGKQA DEVDEDDDVV MGNMDAPSPM SDREGTPSGE EDDGFNFDDD LVFSRDREKL LGSAGNEEKD SNRPDKAMAQ DEDDDDAPIV AANRRRMRAG FVVDSDSE // ID G4LZH9_SCHMA Unreviewed; 1253 AA. AC G4LZH9; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 13-NOV-2013, entry version 9. DE SubName: Full=Timeless, putative; GN ORFNames=Smp_163340; OS Schistosoma mansoni (Blood fluke). OC Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; OC Schistosomatoidea; Schistosomatidae; Schistosoma. OX NCBI_TaxID=6183; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Puerto Rican; RX PubMed=22253936; DOI=10.1371/journal.pntd.0001455; RA Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A., RA De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C., RA Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J., RA Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A., RA Zerlotini A., Dunne D.W., Berriman M.; RT "A systematically improved high quality genome and transcriptome of RT the human blood fluke Schistosoma mansoni."; RL PLoS Negl. Trop. Dis. 6:E1455-E1455(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CABG01000060; CCD60297.1; -; Genomic_DNA. DR EnsemblMetazoa; Smp_163340.1; Smp_163340.1:pep; Smp_163340. DR PhylomeDB; G4LZH9; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1253 AA; 144786 MW; 083FFB41465F1F7C CRC64; MLADPTLRYA DIQACCSCLG FREGDTYKID TDAEVSIRTL LRYLRNETAE CDIRRELGQL RIVSSDLIPL LRCCSGNKTL FELVIRLLMN LTQPAIVCFR QEVPKDRDLY SAYLQVDDLL KSYKKDFADE ELFRVLCDLV GSLLDRSWEE RSEEDRLLIE RILILIRNVL HIAPDVVGEQ RTDEDVSVHD QILWAMHLSG WDELLLFLAN SDDERMFAFH TLEIISLMLR EQTPELLACA GNRAETKSEL NKRRKLIERL KIRDDAERKN FLYACNLRQA RFGGAFELVN TPSLSERPLI YHHDITHTAQ MATVISKQLD SSVDVVDNVG IVELDVGKRK FRKPKHRKPL VDRSIHRRSI LAVQLYLQGF CWQFLKFCYN PIMRVVQSGL TRQATQENDE TYFLWTMRFF MAFCRVYRFR SDYISETLSV PIFHWIYDQV INYKEHLVTN KRGGASNQRA MQAARRLELA VACYKEFLTC LNRMLHVTGA DKTVQPGDDE TQDGVEERLR SQANVAESII ANVFYVAEYQ EVFPNLLRDY NEIFMSKDYL RDLVEGSHLF ITLLSNKICG SNKKIIVKRR RVHRMKKRSS KAKKETRKKA ILNQEPEDVR ISRLKQQWSN QLEGPLIEIL LGTAYQESEQ DESDDEMNDT RLFDATTGNS EDQQLKSAIR RVQAALFAGS AKRALSMAKR MWRLWPEVAP VSIEEDNSAI DAGRAAGLRP ECLNVLGALQ QIHMTELEEE EEEQEALNNS SSNSSDGDDL YNEELGISDS NDELVTTEKE VVLDFSAFML KFVHPRVVHA YTLLLEDYDN NPESVNRAIV HTIHRLAVKE RLTGCFFQLR LFRVFQKFLH DRALATSPEF KELANLIKYI LRKFFEAEER NNYILIETLF FKTPKESYET VQGYGTFESN KKTIHWTSEH DKELTQLFEA YRHDPVPSGN DLADLLVKYF SDSSKTRRQI VARLITLGLI TSLKQLKEIT VRPPKPLSGR NRRLLNNGES SEWTEQEIAR LRDIVELHKG SKNMLTEIMN EIKVDHDLAV QRCLEQELIM DENQSGKYIP PIRARRVVAA KILELGLVDN ENQLKRAVYK RKPEKMQNVD MDVSKGSKKS KSRKKKPSSS TSDDERSMNS SYEEEASTSH SSDSENKTNK STSPEYINQL VESDRPSDQM EHITYVNHTQ DDYISGAVSP NSELGSPKIP VQKRRRLLSS DDENEDGHDT YHSESQMEIR HPKNDEHVGG VFRRVKILSS DSE // ID G4TF23_PIRID Unreviewed; 1467 AA. AC G4TF23; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 03-SEP-2014, entry version 9. DE SubName: Full=Uncharacterized protein; GN ORFNames=PIIN_03856; OS Piriformospora indica (strain DSM 11827). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Agaricomycetes; Sebacinales; Sebacinales group B; Piriformospora. OX NCBI_TaxID=1109443; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DSM 11827; RX PubMed=22022265; DOI=10.1371/journal.ppat.1002290; RA Zuccaro A., Lahrmann U., Gueldener U., Langen G., Pfiffi S., RA Biedenkopf D., Wong P., Samans B., Grimm C., Basiewicz M., Murat C., RA Martin F., Kogel K.-H.; RT "Endophytic life strategies decoded by genome and transcriptome RT analyses of the mutualistic root symbiont Piriformospora indica."; RL PLoS Pathog. 7:E1002290-E1002290(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CAFZ01000067; CCA69916.1; -; Genomic_DNA. DR OMA; LEMASAM; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1467 AA; 162908 MW; 5F0D25098124876E CRC64; MLVKIYAWLS LIGALCITAI EIIRIVLDNV FKKELIDGCV NEVKGRTITT TSGSIFNPNI STSIASDAEA RRICTRAWTS GVWRHVGWLL FAIFISFMFA TINFAFYRQL IDPTMLRTQA PSSAYQMNAT RNAYGYHENG YVLLRAANPI LILYRNIPGY NPYSTQTYGN YVPPSGPGGP AADVKPPGYT TGPEWEQYEH RSADDEKAGF SGAGALNPFA DPGPPSLNAA PGGQGYLPPA GPPPGLEGSR NQGHDEGFDP AALEAAMKAS KNDGRGVPAP GEPSGSELDP ATTGSSSRMS EDEVIDLEHE DHGEDEQQEP LSRRGILEPA IKHVIAALGG VEDTPSGPRY VLGDECYGCL KDLKRFWRKD DTDDERTVAR IFYASAVLPN DLVPIILETA GKGDVLNKCA IAAVDLITGM TWPIDVAAEL RELDEEEEQA AVEYTTLIAA QLSYKRALLT NKETLAAVFD LIVPCMAKPR WDRTERDKQI VTLILYLIRN LAFIRDLPLN TNLSADQAEL SSLQAKFLLT FASNALDDPL ANAQNTLVLE IFYLLFRSIP PNSLLSFSRD ASGRQSSVVN NALRNALDAE TRTSLLQKRN MNSRHSRFGT TVQVSSAQTG QSLILHRGAT AIKAKGAGDV LDLGKKKLAK RARMRDELTG GAASAGGGTA GSGGETRLTS KAREELGKAA RTFVESCFNP FFSSLIKDIR AERSKVTEKD NLRLLFVSKF FMQFFLAVRE GDLADWSMKD AARRKAAESG TDAAVGEVEK ATEDEKMSLG YSLVLEVVQR GWAGWILRRM REAMDMKPKQ WTEVQACLDC LAQLLLLVDS MSNSSDEELQ DAAGTLQYQV YYNGEALERM LECMRSFKDQ SFGYGTYNWY YRMLKRLPVS LKPTFTWRHR TTEEEGVVDD ISEEEEIDTE ILQEMTLEKF EHKFANEEVN ATLLAYLSRF QEFDSPEKMK WVVTLMHRQA VRAKAEGLFF KVSTLALFQT VLSVQRTFPK DQPYKDLVAL ITFLLRQFFK AVEADRMVIA EAFFPKNRGM WKAFSSWEPP EKSKKGKGGR GVEDSDEEAN SRFPPDIRIK KGHSWSEQLG IAIACLLEKD ERHLVEWCKE VGAPSRQLTI DEIDKKRAED GDSDLEGEKQ PGPSKEAREA IEDFIIPYTK DGHAEAANRN PHLKLMFQLL GFQIVDKGAH ELEWKCPANK IPEELQRSLT LINNFLLDPI DLGGKKALQM ISKPTKRKKR GVSPAEADFL DDFSDDEGGR RRANKRVEKR RAEKQNALSR QFIEDSDAEL GDDDAFFAAE AALRRRMAEA AQQDGTVAQG TGTKKRKKKE DHTEKSGDGR ARKRPRKSEE PSVARSKIAI MEGSSNEEES DSPLSPAQRN SRRAAASDDD EVESTRRAAT SPPSSPAASS PVGSDEEREG QGTDKRLSAA SSGKLFFSDS EDEKQVATTR TTRPVKRLVL SDDEEED // ID G4UHF8_NEUT9 Unreviewed; 1235 AA. AC G4UHF8; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 22-JAN-2014, entry version 6. DE SubName: Full=Putative drug resistance protein MdrA; GN ORFNames=NEUTE2DRAFT_155945; OS Neurospora tetrasperma (strain FGSC 2509 / P0656). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; OC Neurospora. OX NCBI_TaxID=510952; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=strain FGSC 2509 / P0656; RX PubMed=21750257; DOI=10.1534/genetics.111.130690; RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A., RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., RA Taylor J.W.; RT "Massive changes in genome architecture accompany the transition to RT self-fertility in the filamentous fungus Neurospora tetrasperma."; RL Genetics 189:55-69(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GL891107; EGZ75497.1; -; Genomic_DNA. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SUPFAM; SSF48371; SSF48371; 4. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1235 AA; 140584 MW; F71C68DE9FFFE60E CRC64; MEAADIIDDV VHPEVRAHIT NLVSALGGYS VDDDGSYKLG DEALDVLRDL KKWIRFYDEK TNRMDVARCL AEANLVGGDL LQILTLWPQS ETDSKYKARI ALACFEVMVP LTWPIEKERA EMTINHHRHM PVLQLAQLGY KRAIINFDAI PILNTAVRVA LPSMAMPIGE RTPRDQAIIK LVLFFLRNVA MIAPPQGVKC EGDETQVSRS ATIDAFSYQD IFLTLLTLAS NMGEDFRTED VVVMEIIFHL VKRVDPSSLF VSEKQLNKAK GQELASEMRK EAAMLKSYNK TTTTRHSRFG TMIWVKRADG KMVTVSGQEA LLDAKTRERK MDNSKTFRPP RRARKPEMEP KDLGPPVTLD ERARQQLRSF VQDFLDSGFN PLFLHVRQSI DREALHVLNQ HKSQFFYLVA WFLEAERMRR KAKRDESKST SAAGEEVNSF NLVAAVLQQE MFASMNRALD RSYSDKDWQL LTSVMRCCTQ IFLTVQEMSE SPNEEDQEIA ENTLSRLFYE ETTHDLIANI ARTYKDQGFE YLDAATELVH TFLRILEGYS KQNVDLQVRS RKRARRKKKA AKAAAAVAAA RAAGEEAEDV GVPEDNDADD SGDDEQHAER VTQERKFEFG KFAIRFAPQG VVDTFVAFTK FYRDLNDAQL KRAHRYFYRV AFKLELSIML FRLDIINLFY NMVQGPEPLD KSSPMFKEWE ELSKQIIRKC IKKLQERPAL FTELLFSKIG STTHFLEHGY EKPVTTTMPR PGAELEFKRA TERDEQIGIA VSVLIDKQQV EHLQWLKDQL TSAMSERQAW ENVDKAMAAT TEGAADGEAA DERSNKSAPP HITIRPDTEA RRTAMFKNPH LRLLMRLVGM ERLTPTLDET PDSTWILPGS HTAEAIQDTI DLINKAEFSP PTFEDGGSAE DQLRRKSAAA SRRTRAAYDD DEEEIRGFLG DDDEEDFLFA PGGPTARKPD ARPQKKRQRK RRREAGSGDE EDEGVSDEVL AARVKKRREK ELEKIRRIKS EMYVHASDDE TDDERDREFF ERERKRQETK DSKFDSLLGA LGLSVLSQVN GGEKSAWEAV LDDEPESDES ENEGRKNAKR RKKQVASGSE EEQEEEEEEE EEEDSDEELP TKQAKSKTSK RKAAALSKRP ARRPGTTKKR AVVELSDDDE DDDEEEDAMD VDSANERTTR NEAPLPSSPG EGLGRRINKM AMDDGDEDED DQPVVAARQR PKARGGFIID SSDEE // ID G4ZY64_PHYSP Unreviewed; 1217 AA. AC G4ZY64; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 06-FEB-2013, entry version 4. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=PHYSODRAFT_255875; OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent) OS (Phytophthora megasperma f. sp. glycines). OC Eukaryota; Stramenopiles; Oomycetes; Peronosporales; Phytophthora. OX NCBI_TaxID=1094619; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=P6497; RX PubMed=16946064; DOI=10.1126/science.1128796; RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H.Y., Aerts A., RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J., RA Damasceno C.M.B., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L., RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., RA Huang W., Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., RA Lee M.-K., McDonald W.H., Medina M., Meijer H.J.G., Nordberg E.K., RA Maclean D.J., Ospina-Giraldo M.D., Morris P.F., Phuntumart V., RA Putnam N.H., Rash S., Rose J.K.C., Sakihama Y., Salamov A.A., RA Savidor A., Scheuring C.F., Smith B.M., Sobral B.W.S., Terry A., RA Torto-Alalibo T.A., Win J., Xu Z., Zhang H., Grigoriev I.V., RA Rokhsar D.S., Boore J.L.; RT "Phytophthora genome sequences uncover evolutionary origins and RT mechanisms of pathogenesis."; RL Science 313:1261-1266(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JH159157; EGZ11970.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1217 AA; 136869 MW; 967B2BC60DC94D8B CRC64; MSSTAAAASG NGSDRDEAAT PTGATAQRDD DELEDFGVSS SDEDADANEP QLDAAMMNEL LLVCSNLGML RVPAPGEAPV LMRGEDCEQW IHDLQRAVRR DHAKHKLVAK QLGKWKILQK KLLPLLVNHQ HDWSLVFSIL KVLVMLTMKP ARDSTNIAQQ LKYLRQYKHE FLRCGVIPIM MTILVDPLSR KGSARTAQDY LNMEIVLTLI RNLLAIPNED PRFVTSTTSY FSHLQEDFIC TLHEENVYEM ILLFAQDIDS QENREWNLLI MEMIDLTLDC SQPKSVVAFA KKQLTGETAK GSGAQPAANS TPVGNSRPSR NAAPAGGDLL AKLNSEKKAS ALHQSGSRRH SNFGGVLTMV GPTGRTTVLS DFSKTVYDQV PQAAKKPVSR RRGKKNAAPV TDIQEIFGGK GKVTESDEWV AYDAGSPRDR LQYFHLVWFL TTYHRLKVQA LKSHYKHQLK AVQKKTTELQ NALDFTTPPP PAPEKPDYDE KAVLSTLDMF SFNFVLQSIE NYATMKNYHG MTVSVQLLAE MMAYLAELTA SDDPRFQRIA DSLQHKIFYE RDFLDRLPVL LKTWSPGLFP KAYVVDVVTL THLVFKVLDS QGTIKVLSRR KAYLDKKRLK KKRGDGESKE GEDSDGSSTD EEETERQAQL LMEMQRKEAD FDVRKYFSSM LSSDTIRMYC SLLADYRENS AKVNHYIHSF FYRTKHFQIY QQEEWTMQPI LFNIHVLLLF NKMLQDTYIQ RLPEYKNFLD FIRGVVRDFF SLADKNNLLF VEALLRQPYP SKSCMLIQRN YDPIDSMSKS KSEAVALGRE RRIEAINESR RHRIALDHEE LEGEAEFQFT LGPSDFQSTS LVDKEGQQEE GEAEFNADDA SSNPSEGASP AKPKPKRKAP ISRAATERAK NWSKVEDRYL AKVFMKYRHL PSVYEVISYE DMFQERDRTP EQIERRVKYL KLHRKTHDSS DEDENDQTNS DGEQNGEQEE STEAVRESRL EKDLATLDTA RPRRRLRRGA DLSDEDSDDD MLLGGSTQAT AEPSQSTNTG DAPTGGEPAT ASNAVHDEEM NAEDSSTEVQ PSKTLHDDAS QTQDMEDTQV LEDGIREEQS TEAEATQELD SVEDVAANDP AVSSPAPANV AAEDSAMTGV ELPDATEAVT AEMEVANLNG SQEPTNPESD TADVQSLKRG RSDENADDEA EIEGTPAKKV HRTEAEEPTA DASAREQ // ID G5EDN3_CAEEL Unreviewed; 1353 AA. AC G5EDN3; DT 14-DEC-2011, integrated into UniProtKB/TrEMBL. DT 14-DEC-2011, sequence version 1. DT 03-SEP-2014, entry version 22. DE SubName: Full=Protein TIM-1; DE SubName: Full=TIM-1; GN Name=tim-1; ORFNames=CELE_Y75B8A.22, Y75B8A.22; OS Caenorhabditis elegans. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=6239; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Bristol N2; RG Caenorhabditis elegans Sequencing Consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Bristol N2; RX PubMed=9851916; DOI=10.1126/science.282.5396.2012; RG The C. elegans sequencing consortium; RT "Genome sequence of the nematode C. elegans: a platform for RT investigating biology."; RL Science 282:2012-2018(1998). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Bristol N2; RG WormBase Consortium; RA Barlow K.; RL Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Bristol N2; RX PubMed=10550049; DOI=10.1126/science.286.5442.1141; RA Jeon M., Gardner H.F., Miller E.A., Deshler J., Rougvie A.E.; RT "Similarity of the C. elegans developmental timing protein LIN-42 to RT circadian rhythm proteins."; RL Science 286:1141-1146(1999). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF183401; AAF13189.1; -; mRNA. DR EMBL; AL033514; CAA22106.3; -; Genomic_DNA. DR PIR; T27404; T27404. DR RefSeq; NP_499594.2; NM_067193.5. DR UniGene; Cel.19544; -. DR EnsemblMetazoa; Y75B8A.22.1; Y75B8A.22.1; WBGene00006571. DR EnsemblMetazoa; Y75B8A.22.2; Y75B8A.22.2; WBGene00006571. DR GeneID; 176652; -. DR KEGG; cel:CELE_Y75B8A.22; -. DR CTD; 176652; -. DR WormBase; Y75B8A.22; CE23033; WBGene00006571; tim-1. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OMA; ARIECGR; -. DR NextBio; 893466; -. DR PRO; PR:G5EDN3; -. DR GO; GO:0005634; C:nucleus; IDA:WormBase. DR GO; GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase. DR GO; GO:0051177; P:meiotic sister chromatid cohesion; IMP:WormBase. DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:WormBase. DR GO; GO:0007063; P:regulation of sister chromatid cohesion; IMP:WormBase. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 1353 AA; 157011 MW; 6A0F730A7912A3EE CRC64; MNVLVQGAVH ALGYYEDGKY SREPDCYESI RDLIRYLRED GDDHTARIEC GRHNLVEQDL VPMVKCEDLT DDEFDIAIRL MVNLCQPAIS TMRGKPPADR DQWKMYWELE ENLRRAKTAF SDAHFFTAIK KRIDNYFIDT EYEDRDERLR LVVERIVLLI KYVFSINPDT SEGRRTRIED SSHDRVIIAF LESGIDKTLM HIANQPREKE FHVTILDIFA LILKEQTAED LATKSEEVST AEQKKTEEEF RKIIENHVVK ETQKRKSFSR FGGSYTIKGL KGISANSSQV VFKPIQNVEK HNFLDDRKAK KRAPRNRRPF EIDTNSHFAS SEVRGMLRDM VIRIIETCFN RLMKSSKTTV FVQVQKTSQI NYFFLIKFVL RFVRLSRQDH LLERISECIG VEAFHENNVQ LTEYVENATT LKGVEAKSHG LKAQYALGAY NELVLLHRYI YEHAKEENER KFAKRALEHI VNVEEYRELP IFIIKKFSSS VLSNNFLREL VLTTHHYMKL VERFVKTGAL KKVTKKVKVR KATKKSKMSE EDVRSEFDGM SKKDLDRLWE ESKGLVLQIL KKEVPEMRGM NPIDSQLDVP VDAQQKFAKL SIQRSLRSRG FPAAVGLYHA SRALWPESFK RGLTDFQDSP GEEDQLQELE QLLKADMKKV AKDLKKAESC KTCDEDPAYK KYDKMDATAL QSLWEQSTDT LARILSHELP ESESTSPVNW QLDITPDVQQ KFAMLAIQRA LRARDLPAAV GLYHTSRKLW PGDEAIFGAP GIGVEEEIAE LKAILEADLH EVAREMKVAE DRAEDPDEED PAEPYDSEQE EEEEVPAWKV EEIDFQFDSY VCKFSNVDVL KWYVFLLNDF SKNSTELNQA LVKMLHRIAF DLKLPIKLYQ VSLFQVFSKV NEHFTHLSKD LRKSSRLYEL YQFGFHLLKK FFSKFTGDLA IEALFWKGPR ECFEIENGYG SWVKSREADI RVWTEDLEIE LRNLYEEYRT METRDGIDVL DFIEHNLSRA RSRKKVAKKL IEFGFDLLGA KWKNSDKARM DSVLPIGDIQ KWYDEWKEAG ARGDLVNVLQ EKLNEDLGME ISRKKILKQL AHMDILYEKP KKEKPLPQWD TGLIEELKKL KEQYDDIPDA LNMLGVNIVR YVMKRLSEKK PTRQVERHLE SLGATIPERS KKSEKNGKKF DDFLNDDDDD SENDVGGGSE DDEEEEIVMK SKRIIPDSED EEEHIEQEEA QKKLEKVAEK PNTLMGMIAG RKRKLAQLES DSSDESDDDD SAEKEEKKLP AAEDDSDLEE DAVIYKRSYV DALLTGGSIA GNGITETRRD TSEEREDDDD EDPFTKKLTF KRRIVMSDNE DEA // ID G6CPX7_DANPL Unreviewed; 1254 AA. AC G6CPX7; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Timeout; GN ORFNames=KGM_10605; OS Danaus plexippus (Monarch butterfly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Papilionoidea; Nymphalidae; Danainae; Danaini; Danaina; Danaus; OC Danaus. OX NCBI_TaxID=13037; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=F-2; RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052; RA Zhan S., Merlin C., Boore J.L., Reppert S.M.; RT "The monarch butterfly genome yields insights into long-distance RT migration."; RL Cell 147:1171-1185(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AGBW01002510; EHJ76705.1; -; Genomic_DNA. DR EnsemblMetazoa; EHJ76705; EHJ76705; KGM_10605. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1254 AA; 146430 MW; 609B0B64FFA462D5 CRC64; MSSLLSAELS ATCNALGTFN KKTGKYMIDD FTLNTVKDLI RYLRRDGEDH EIRRHFGQTK VLQTDLLPML IDHWENEELF DVTLRLIVNL TNPALLLYRE EVPVERNDRH NYLQILSHLQ SYKEDAFTKV ENWQVFAKKL GKVLEIDWSE RDEDTGLVIE RILILIRNVL HVPADLDKER RPENDASVHD QVLWALNQAG ILDIILYMSS ENEKQYFMHI IEIISHLLRE QNPSSLADAA LQRSVDEKVR DDQELLMIRM TENKDRMNKI RHYSSTRHSR FGGTYVVQNM KSISDNELIC LKPLNKISNL DFNGSKKQKL VKPKNRRPTE SGTMERRSAF AIRLFLKEFC IEFLNSSYNV LMHYVKDVLV RAKAQQNDES YYLWAVKFFM EFNRAHDFQV GFVSETMSVP MFHYVQQQME KYYDMISVEK KKFTNWVRRL HLALRAYKEL LHTLLAMDAS KDHTVRESAK VLKSNIFYVL EYREFILSMY LNYDENKMPR SYLVDLVETV HLFLKMLEHY CKRTGLVVQK KVRKKTKAKK QKPKIKPKVI ELSPWEEIRP QLAAVLSSGV ERYLPPFDAA SETPIDQQKE DCMKKIQRLM RDHKYEDVIG TFRAAREVWP EDGIFGVSGM PEDEELDMLE TIYNTDLGLD YEVAQHEDAQ EYSEDEDEED EEQGSAAIVE TDFDFQDFVL RFCHPKIVSA CVCLLERYDK NRSHTNHCIV KMLHRIAFDC NRPAMMFQAT LFLTFQKILH NPMPHLKELE KFAIFILRKF ADIASKSGKV FIELLFWKNS KDAVEIEHGY NLYNDPRDKL GKASWSEEQE DELRNLYMEN QTNPQTDQDV IDWILDNLID QTRTRRSVIK KLKELGLIFN APTKKSNKAR TEKVTKDFTE EEDKLLTELW TQYAESQDPM SVIMERMPRN RSKRTFVERL LRLGLIDDKK QCRKKSIKNI SGKNSSDSES SKSEDEDAPP KRPTIKIKSK KNLTKSKQSN KKSAESLELS ANEIAELLVQ AVENGHTEAL NWLSENLEEV ALDQEAEGFD PTSEGTPLVP ISRESVQAIQ DDLFRRVLKS LGIVPPVDEQ ETYWRIPSSL HYETIRKRRE IITKAVNKEL IIDNRAAPET KEDNNDNGNH GNHNINDESD ASDDDLFDNL RKIAKKSSET DNPKSKNRKR TRSFESDDEN KKKQRKDNIK DKDDENENEN KDSDDDLLSF VKNTLHTELP DTEDILNALP EHSDDSDAEV APKRRKLRIL SDSE // ID G6DEW8_DANPL Unreviewed; 1210 AA. AC G6DEW8; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Timeless; GN ORFNames=KGM_08466; OS Danaus plexippus (Monarch butterfly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Papilionoidea; Nymphalidae; Danainae; Danaini; Danaina; Danaus; OC Danaus. OX NCBI_TaxID=13037; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=F-2; RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052; RA Zhan S., Merlin C., Boore J.L., Reppert S.M.; RT "The monarch butterfly genome yields insights into long-distance RT migration."; RL Cell 147:1171-1185(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AGBW01008102; EHJ67997.1; -; Genomic_DNA. DR EnsemblMetazoa; EHJ67997; EHJ67997; KGM_08466. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1210 AA; 137425 MW; 3619643937E6DF8A CRC64; MEWVHRSPQI HSTFSNLGFT NGDGYHINEN YNAVLESILQ NILTEDKQLR SYRRSINFGQ NIKKDLIPLL INTKDDKTIV LVIKILVNLT IPVECLLSLD SVGRTDVGRH TIFEINNLLT STKAAITDHR VTKVVIDFLK KNAEIDQSSK LSSDECTNIS NGLLLLRNIL HIPEEINNPS YNPRTVQNQI LWNLFSQSID KVLIKLMNIT DAINWGVTMV QIIALLYKDQ HVTTLQKLLN LWLEASLSES SEDNESNTSP PNRGSDDSSP MLTSDPTSDS SDAGASGKSN GEQNSVNNSW DSSSRNNSDN GKPSFDSQKE NELANDSSES NENNMYIGNS KDNLEESSSN DNNHISNDHS NSHNMKNNEK KTIISEPSDC GYGTQIENRE SISTSSNEDE LPTTKPVHQK PHNTKQRTNN KVRAGVTLQD RKRKKIVKRG KANIINVQGL LHNTPTDDDI SNVLKEFTVD FLLKGYNSLV RTLHTQILTN VQLEIDTSHF FWLVTYFLKF ATQIELDLEH VCSVLSYEII LYLTAEGVNL CEQFELAIKL DGSDLKPSIR RLHLVVTAIR EFVQAIEVYK KSAHLSSNDQ EKLLKLQMKM AQTEELRSLL VLLLRHYHPK YHSKQYLQDL IVTNHILLMF LDSVMKLPQY EGPNTMVDHI KQFASPEIMH QYGLLLEDYE GNGGFVNDCI FTLMHHVGGE LGSLISLFQP KILKTFTSIW KSEFEICDDW SDLIEYVINT FIKKPYKLQN YSNIQLEMEI FDDDMKPKEN LIDPEPAPEI ISVMKKVNEN ENITDGWNEE EISSLNWNYM QCNTAVDVVE EILRMLKEDG IVKTRESIIK ELYRQLIINK EEFEGLSKVD SDKNSKAIRD KRENEIGKLC EQLRQDGKSL FLDWVQAVLL ETCFAKIHVN KIEVDRVRQS SYTTQDAHRH VFDTMLKRNT DMPVISPVSY HSLLLNQSVP LVPWNNEQAA VCKDLKFLQL AHKLGFHMPV DTGKVLIRIP NFWTPDFLYE VAEKISPINK SKLRFSLSDI NACGGGGGCQ ARGVLSEPPP GTHDYFQIHK QKHVATIVNF TPMPGPSFST TDEDYKPNWL EMVQKSQEYK ITLDLGKSIL TEEVVVSKSS VEAPPVAVLP PALVLPSAIN MKQDGSGYVN NDSEYNSVCE TASVASDLTR MYVSDEDDKP EPLRHVKPRD LAPDDASAEK RPRVQFTEHF // ID G7E123_MIXOS Unreviewed; 1175 AA. AC G7E123; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 5. DE SubName: Full=Uncharacterized protein; GN Name=Mo03201; ORFNames=E5Q_03201; OS Mixia osmundae (strain CBS 9802 / IAM 14324 / JCM 22182 / KY 12970). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Pucciniomycotina; OC Mixiomycetes; Mixiales; Mixiaceae; Mixia. OX NCBI_TaxID=764103; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 9802 / IAM 14324 / JCM 22182 / KY 12970; RX PubMed=21478649; DOI=10.2323/jgam.57.63; RA Nishida H., Nagatsuka Y., Sugiyama J.; RT "Draft genome sequencing of the enigmatic basidiomycete Mixia RT osmundae."; RL J. Gen. Appl. Microbiol. 57:63-67(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BABT02000102; GAA96533.1; -; Genomic_DNA. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1175 AA; 132187 MW; 5C4F731A514709A7 CRC64; MGRYDVDEID EEPYESLSEE ETLTQYGDDE KDDRQARKDD QVQGEDGEPL TRRELFKPAI VSICSALGGF EEETTESGEY VSVYKLGDEC LKCLKDLKRF WRMDDQDDDR TVARLCFETG VLSKDLLPIL LSQAGTGPRG DKIALACADL IGAMTWPIDV AEELKEAAEE AAIRGGPDAP RVDFASLLRI QLTYKAAILK ANAVETILKL CVPSLAKPRR DRTEKDANII TLVLHIFRNL AAIKDRPRSA ATSTQAVQDS TLQSELIQSM NRHEVFQVLL NIAHLSMGNE FRVWNLVVLD IFHLIFRGCK PADLVGDVDK STSKGLQSLL EAEDSRKRID QRKGSSRHNR FGTTLTLRTT ERSYTLHKQS AVNVSPTKII DRVKKTKAKP LKIQDELTTP TELTPEALKA LQQIAQQFIE SCFNNFFESV GGDIRAERPK VREADHLRYL FLSRFFLEYF LLLIASEKAA GIDPSSEQGH DFDLVADMTE IDTVNLVTKR MRIGLDDKPV RHSEVQGAVE LFTQILLLLE SLSASSNEDH RDVAQVMQDK IYYEEEILAT AITVVDRYGK RNTLQYLESV IHFAYTMLRT LERYSKSTAH MYVRSKRKKI AQRKKRAAGE AADDGHDEDS RPDSGARSKS EHAFNFAQFE ARFATEATLN TCVAYLRGYK TFRSDEQMKR IVGLMHRQAV KANNAALFWK ISTLTLFGEI HSDRQLLPST RSYNDLYKFV EFVLRGFFKA AQQAPLVIVE ALFPHRKSDV KRLQSGFAQE DEDNSDDEVA TRALKMPAEL VVKRGFTQTQ QMGIAISLLA DAYKEYLLDW VKDTLRTVLR ARKEVVEEID GPPETQMDLT EDIDDAELKR RHELASKPSE AALAAFQAYD VPYDDADTEK AATKDPQLQL LLRLISWESR IPEHNKFVIW TVPARRLPKE MEADLRMIDD FLINPLDANT GQSAAELVRK QAKKRPKRAR VGSDGLELSE EEPVPSRKRT RKQDEQRQAY LSTQFIASSD EEEGLDQYAD FFAKEAEAKR KRDAGGIVGG SVQPISQMSQ QLKVVKPPAE PMPAPVALTD RSESSQSPVA SKHTDPSSST PPSSLPLSHP SSPEPSAPIT VRSKDVRRSS SPAIRKLSKR RKRSVGSSGS DAEDGMPSSA RALSLSPQRP AMRRKPQKIV DSDSE // ID G7IDV7_MEDTR Unreviewed; 1335 AA. AC G7IDV7; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 03-SEP-2014, entry version 13. DE SubName: Full=Topoisomerase 1-associated factor; GN ORFNames=MTR_1g099370; OS Medicago truncatula (Barrel medic) (Medicago tribuloides). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; OC Trifolieae; Medicago. OX NCBI_TaxID=3880; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Jemalong A17; RX PubMed=22089132; DOI=10.1038/nature10625; RA Young N.D., Debelle F., Oldroyd G.E.D., Geurts R., Cannon S.B., RA Udvardi M.K., Benedito V.A., Mayer K.F.X., Gouzy J., Schoof H., RA Van de Peer Y., Proost S., Cook D.R., Meyers B.C., Spannagl M., RA Cheung F., De Mita S., Krishnakumar V., Gundlach H., Zhou S., RA Mudge J., Bharti A.K., Murray J.D., Naoumkina M.A., Rosen B., RA Silverstein K.A.T., Tang H., Rombauts S., Zhao P.X., Zhou P., RA Barbe V., Bardou P., Bechner M., Bellec A., Berger A., Berges H., RA Bidwell S., Bisseling T., Choisne N., Couloux A., Denny R., RA Deshpande S., Dai X., Doyle J.J., Dudez A.-M., Farmer A.D., RA Fouteau S., Franken C., Gibelin C., Gish J., Goldstein S., RA Gonzalez A.J., Green P.J., Hallab A., Hartog M., Hua A., RA Humphray S.J., Jeong D.-H., Jing Y., Jocker A., Kenton S.M., RA Kim D.-J., Klee K., Lai H., Lang C., Lin S., Macmil S.L., RA Magdelenat G., Matthews L., McCorrison J., Monaghan E.L., Mun J.-H., RA Najar F.Z., Nicholson C., Noirot C., O'Bleness M., Paule C.R., RA Poulain J., Prion F., Qin B., Qu C., Retzel E.F., Riddle C., RA Sallet E., Samain S., Samson N., Sanders I., Saurat O., Scarpelli C., RA Schiex T., Segurens B., Severin A.J., Sherrier D.J., Shi R., Sims S., RA Singer S.R., Sinharoy S., Sterck L., Viollet A., Wang B.-B., Wang K., RA Wang M., Wang X., Warfsmann J., Weissenbach J., White D.D., RA White J.D., Wiley G.B., Wincker P., Xing Y., Yang L., Yao Z., Ying F., RA Zhai J., Zhou L., Zuber A., Denarie J., Dixon R.A., May G.D., RA Schwartz D.C., Rogers J., Quetier F., Town C.D., Roe B.A.; RT "The Medicago genome provides insight into the evolution of rhizobial RT symbioses."; RL Nature 480:520-524(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM001217; AES62410.1; -; Genomic_DNA. DR RefSeq; XP_003592159.1; XM_003592111.1. DR UniGene; Mtr.24746; -. DR GeneID; 11424152; -. DR KEGG; mtr:MTR_1g099370; -. DR KO; K03155; -. DR OMA; HKQPKSD; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1335 AA; 152158 MW; 56ED16EBEF2BC12C CRC64; MDTDGLSLIC SGLGAIEEDD EGKRIGYSKG EYCLDNLKDL LRFLRRDDPQ SRDVFKLVCK WNIVSKDLVP IIEHYHQDRS MLLNAVKVLV FLTMPIEPGS TEVSQQLEYL WDLKSAVTNG DVVTVIVSIL EKPLENLELN KFTEDDWKLV QLVFTLFRNI LAVQEIPLHL KSAGSASHFL SLRDKFLDLL FRENVMDIIL VVSQNVGSSN VYLRQDNLLL LEIFHYIFMG QDPELIIRGY SNGSKADEDS QASLDSLQSI MEEEKKKRII SRLGNIGRHS QFNATFARVT MDGSKAVVKG NPNSSHNMHL KSQNVTRGRA KTIAWDHPKL PSTTDTILEL LRGFVDQFLS VGYNVLMRSV REDIEKEHPA VQKTDVVFFF QVAEFVTSFQ FYKHSTSKIK EERHAFDDND ADASDYSGKI CGPIEASLNE SMFQLVISKW RQAYDGLKET NDYMFLSAAG SLLKNMIRML DLVLKLLPED SKEPQTARIL LYKLFYDQTE EGMTQFLLNL IKTFDTHKQC KSALADLVEI ICKVVKLMDH LQSRGTLRVS KKARKLKKKI SSARESENKP TGDQSCIQKE ASISIDNQLA ENQLLQKESI PNANSTEQED TPHDNEHQNL EKDVNSQVRL KPMENRNLDD NGDNNVKRDV NFEIGVESVR NTNLDDNKNE DVEEDVNSQV GMKPMENTNP EHPNEDMLDD TGDFSEDEQI NAVSEVDFNV STLVSAFANH SIIQKLCWLL KFYKSNSLAI NHYIISMLRR ISDDLELHPM LYQLSLLTIF YDILAEQKSR PCEEYASIVD FLNSLVRKML KKMKKQPLLF VEVLFWKTRR ECHYINAEYL LDELGHLKNE TKNWNDTQGD GEIGSSPGKP WTRRSLADAL GDDEADVVIS HDSRYQNNGE KLDDIEGIAS TSGSKNDRDD NNGEPWLEDE YQTAPRRKKK LILDAELEIQ IKDLYEKFKD DRNCSRRIAE VLDPDGKIST AQISSKLKKL GLTIASRKKK GDADETFSTS PNQLEGGGLA GGVNHTSVEG SLLIQHRQKR KRVSAFNEDQ EARIKVLFED FKDHRRCSYM IANALDKDGK FTPAQVSRKL KQLGLCVPQK SFRGKNHQKG EDLMDGSNDR MHESDEDTLI SLVKRKKGKN RKESSEQLRE QTNEDKLSKD DSDDEMLASI LKKKGKNRNI SSEQLQEQTG EDKLSKDDSD DEILGSILKK KVKNRKESRK QLQEQTGEDK LSKDDLDEEI LGSILKKKRN GSVSSDYLHE STNEDELSRD DSEDEMLQSA PNENQGGFVN SHQVENMQVD PDLEDSEDEV AVDTLPDNAV SRRKLRMVVD LEDDD // ID G7N7D1_MACMU Unreviewed; 1206 AA. AC G7N7D1; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 21-MAR-2012, entry version 2. DE SubName: Full=Protein timeless-like protein; GN ORFNames=EGK_03805; OS Macaca mulatta (Rhesus macaque). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9544; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CR-5; RX PubMed=22002653; DOI=10.1038/nbt.1992; RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., RA Li Q., Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., RA Huang Z., Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., RA Huang Y., Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., RA Li B., Liu X., Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., RA Li Y., Wang W., Katze M.G., Su B., Nielsen R., Yang H., Wang J., RA Wang X., Wang J.; RT "Genome sequencing and comparison of two nonhuman primate animal RT models, the cynomolgus and Chinese rhesus macaques."; RL Nat. Biotechnol. 29:1019-1023(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM001263; EHH20866.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; SQ SEQUENCE 1206 AA; 138964 MW; AAE0EDE0B4171DFD CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASIHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGIGQG RLAQERSADV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDLSPNEA VRESSRIIKN NIFYVMEYRE LFLTLFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRRKKKKVLD QATVSGNVPS SPEELEAMWP ALAEQLECCA QNPELGIDSM VPFDAASEVP VEEQRAEAMV RIQDCLLAGQ APQALTLLRS AREVWPEGDV FGSQDISPEE EIQLLKQILS APLPRQQGPE ECGTEEEEEE EEEEEEEELQ VVQVSEKEFN FLDYLKRFAC STVVRAYVLL LRSYQQNSAH TNHCIVKMLH RLAHDLKMEA LLFQLSVFCL FNRLLSDPAA GAYKELVTFA KYILGKFFAL ASVNQKAFVE LLFWKNTAVV REMTEGYGSL DDRSSSRRAP TWSPEEEARL RELYLAHKDV EGQDVVEAIL AHLNTVPRTR KQIIHHLVQL GLADSVKDFQ RKGTHIVLWT GDQELELQRL FEEFQDSDDV LGHIMKNITA KRSRARIVDK LLALGLVAER RELYKKRRKK LASSILPNGA ESLKDFCQED LEEEEKLPEE DSEEDEEGSS EAEEVQGSLV LSTENLGQSL HQEGFSTPLL WLQHCLIRAA DDREEDGCSQ AVPLVPLTEE NEEAMENEQF QQLLRKLGVR PPASEQETFW RIPAKLSPTQ LRRVAASLNQ PEEEQKLQPE LQPEVPGEEG SDEEHCKEHR PQALRALLLT HKKKGLASPE EEDTVGKEQL KTAPKKRQLL DSDEEQEDEG RNRAPELAAP RIQKKKRFQI EDDEDD // ID G7PII1_MACFA Unreviewed; 1207 AA. AC G7PII1; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 21-MAR-2012, entry version 2. DE SubName: Full=Protein timeless-like protein; GN ORFNames=EGM_03388; OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Cercopithecidae; Cercopithecinae; Macaca. OX NCBI_TaxID=9541; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CE-4; RX PubMed=22002653; DOI=10.1038/nbt.1992; RA Yan G., Zhang G., Fang X., Zhang Y., Li C., Ling F., Cooper D.N., RA Li Q., Li Y., van Gool A.J., Du H., Chen J., Chen R., Zhang P., RA Huang Z., Thompson J.R., Meng Y., Bai Y., Wang J., Zhuo M., Wang T., RA Huang Y., Wei L., Li J., Wang Z., Hu H., Yang P., Le L., Stenson P.D., RA Li B., Liu X., Ball E.V., An N., Huang Q., Zhang Y., Fan W., Zhang X., RA Li Y., Wang W., Katze M.G., Su B., Nielsen R., Yang H., Wang J., RA Wang X., Wang J.; RT "Genome sequencing and comparison of two nonhuman primate animal RT models, the cynomolgus and Chinese rhesus macaques."; RL Nat. Biotechnol. 29:1019-1023(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM001286; EHH66404.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1207 AA; 139092 MW; 813A1BE85700CC3F CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASIHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGIGQG RLAQERSADV AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDLSPDEA VRESSRIIKN NIFYVMEYRE LFLTLFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRRKKKKVLD QATVSGNVPS SPEELEAMWP ALAEQLECCA QNPELGIDSM VPFDAASEVP VEEQRAEAMV RIQDCLLAGQ APQALTLLRS AREVWPEGDV FGSQDISPEE EIQLLKQILS APLPRQQGPE ECGTEEEEEE EEEEEEEEEL QVVQVSEKEF NFLDYLKRFA CSTVVRAYVL LLRSYQQNSA HTNHCIVKML HRLAHDLKME ALLFQLSVFC LFNRLLSDPA AGAYKELVTF AKYILGKFFA LAAVNQKAFV ELLFWKNTAV VREMTEGYGS LDDRSSSRRA PTWSPEEEAR LRELYLAHKD VEGQDVVEAI LAHLNTVPRT RKQIIHHLVQ LGLADSVKDF QRKGTHIVLW TGDQELELQR LFEEFQDSDD VLGHIMKNIT AKRSRARIVD KLLALGLVAE RRELYKKRRK KLASSILPNG AESLKDFCQE DLEEEEKLPE EDSEEDEEGS SEAEEVQGSL VLSTENLGQS LHQEGFSTPL LWLQHCLIRA ADDREEDGCS QAVPLVPLTE ENEEAMENEQ FQQLLRKLGV RPPASEQETF WRIPAKLSPT QLRRVAASLN QPEEEQKLQP ELQPEVPGEE GSDEEHCKEH RPQALRALLL THKKKGLASP EEEDTLGKEQ LKTAPKKRQL LDSDEEQEDE GRNRAPELAA PRIQKKKRFQ IEDDEDD // ID G7XJL7_ASPKW Unreviewed; 1058 AA. AC G7XJL7; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 16-APR-2014, entry version 10. DE SubName: Full=Topoisomerase 1-associated factor 1; DE Flags: Fragment; GN ORFNames=AKAW_05346; OS Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus OS awamori var. kawachi). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=1033177; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NBRC 4308; RX PubMed=22045919; DOI=10.1128/EC.05224-11; RA Futagami T., Mori K., Yamashita A., Wada S., Kajiwara Y., RA Takashita H., Omori T., Takegawa K., Tashiro K., Kuhara S., Goto M.; RT "Genome sequence of the white koji mold Aspergillus kawachii IFO 4308, RT used for brewing the Japanese distilled spirit shochu."; RL Eukaryot. Cell 10:1586-1587(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DF126458; GAA87232.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Isomerase. FT NON_TER 1058 1058 SQ SEQUENCE 1058 AA; 122136 MW; FDA5D0D60FF939BC CRC64; LLVPLTWPVE LHGELTINHH RHIPYIQHVH VSYKRGLLSH ASTSYLRTII RVGIPSMAIP RSERTTRDEG ILKLLLYLLR NIALITPNTR LAAEGDEEET SRSATINAFQ DQDVFALLLT MCSNVGDDFT MQDVALLEIL FHLIRGVNVE KLFMDDEQRT AKRTDELDDL LRQESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKYSTVSG QNVLKDSQAT LQKMDETKKW NKPLIRRKPQ DLTVHNDFST PVHLNSTASN NLRMFVEEFL DSGFNPLLTH VRKAIEREAD RVMDINTRQF LYTTAWFLEA ERARRARQRK KHAESEKPAK ELEPDSFGLV AGVLNQETFV FLNRAMQYAL DNKDWEDLNA GMRCFTQILL TVQDMAQSPL EEDQEIAENI QNRIFYEETT HDRVLAVIRG YKDQPFGYLD ACTELTHVFL RMLERYSKEN LDMQVRSRRR ARRKAKDVEG AGNDENDEEN GSEDEDRMEA ERVSKERKFD FRRFAAKFCN QKCVDTFVAF TKHYKELNTE QLKRAHRYFY RIAFKQELSV LLFRLDIINL FYRMIKGPGA LDSSKPIFKE WEEFVRQIIR RLTKRLDQRP ALFVELLFSK INATTFYLEY GHERQTVTRA RKAPAELEID PRQAHTIEEK ISIMVPALVL DGEEDLVSWV SDVLGSAVEE REAWEAQEKA LREAGAENSR MPNPMISVKA RDDACQQAMF SNAKLRLLMT LVKFERLGAE DVPGAAWVIP SAPKAQDLRE MKSFIDKYFE KAKRGTLGRD PRELIRRKYG GGKKSSDNQY NPDIHFGDDS EGEDEVPDGP LFPPNPRAAP NPAKKPTKKK KRKERDPDDE DEDDSVDEET LEERRRARLE NSRARLAKIK SDLYVHASDE DTDEEGDKEF FLLEEKRRKE QAQRIRHALL TGMTEDGDGP TNKKGQRKRQ TNLTRTGEAK SKRQRRGKQT DEVDEDDDVV MGNMDAPSPM SEKEGTPSEE ADDGFNFDDD LVFSRDREKL LGSAGTEDQD SSKPDEAMAQ DEDDDDAPVV ATNRRRMRAG FVVDSDSE // ID G8BHK9_CANPC Unreviewed; 1156 AA. AC G8BHK9; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 4. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=CPAR2_501590; OS Candida parapsilosis (strain CDC 317 / ATCC MYA-4646) (Yeast) (Monilia OS parapsilosis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=578454; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CDC 317 / ATCC MYA-4646; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). RN [2] RP GENOME REANNOTATION. RC STRAIN=CDC 317 / ATCC MYA-4646; RX PubMed=22192698; DOI=10.1186/1471-2164-12-628; RA Guida A., Lindstaedt C., Maguire S.L., Ding C., Higgins D.G., RA Corton N.J., Berriman M., Butler G.; RT "Using RNA-seq to determine the transcriptional landscape and the RT hypoxic response of the pathogenic yeast Candida parapsilosis."; RL BMC Genomics 12:628-628(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE605207; CCE43934.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1156 AA; 132165 MW; B89A3504BD6FC8B6 CRC64; MDSYVEVDMS DVETGSDIEN YYDAEEFDDF IDYGDEEVTK IKLPKKHETI AGQSADQPIE IDHDKGSAEG GVVEEEEEEE EEEEEEDRLR SLSTTLKPNE THAQKLLRAH IAILVSALGG VDHTSEVKPP PYKLGHDALA CLKDIKRWIR AVDEKQNNYE VALACADCGL IQNDILVILC QWEQKMAKKE IIRNKTSMEK IMLSCLEILV LLTWPVDFDK NLSDNQKLLY ANIRKIHVSY KKHILTYNGG QLLKAVIRLV LPVLQKSKID REPRENQILR LVLYLVRNIL AIEPATSSIS SKARNTIVAS ADLPSGVSQD DISINNVLKV FKRNKVLMLL LTISGSINVE FDKELFGEVT LECIYLMIKG IEAKDVLVRP PPLPYAPSVS TDASAPLAPL SSTVGMQLSD LLATEARKKQ AQTSKIATRH GKFGTLLSIR SSDATSYVVS GEEALANTDG TLDKLDKSKT WKNPNHFKYD SDDYVQTSSP VYLTAQGRHI FFEFIDEFLS GGCFNNLIEV MASKLTSQSE YSTVDDLSNA SYFFTIAWFL NYQREQIMLN NTASFDFGSV RAALSEINFI LIVTYFRDSF AKKSWNSLHV AMICFKELLQ ISNSIFGKKR TTTDEEEEDT QYEIDRELAE GIIRKLFSFN DFLNILVLIP QSAFKHSPRF LKQSIHVITI ILKSFESFAK EDLQLYVQTK RKQGKQNRKR INELNRDTDA KLSAAIYDSD DEAIAENIRE VTRERRLNFQ ATEVRFFHQA IVTAYIEYLS RFQDLTHDDI KICLSYFHKL FVVRKDYNGL FRLDFMQMLH KLKSHLPRGS SIRLKVEEFI YYFMKKFKVA LGRFPNIIEV LFPRIEESAC KCYLSTGDLY EKEDLLERRF ERKLQQQGDG DKAYKGDGEE DGDGDGDDDD IAFELDANPN SSRQHGTELD LLDELEAQLN SQHQPRSKNL EPGKAHKRRS KTKTKPSKSN ETSRRRIIPA GLLEDSQPAR SAEFVHDSDD DSDDERHQEF FVREERLRKL LNEIGSITNN EKLEEFKKVW SVYSKNGNKE VANVVNNAVE EVSLFVEEEE EEDDDEGEKE EVEEGDLTQS HTVNNALLES EDSDPRQSEE EDEPDHSSSN TSDMDSDNNN KRAQTEEHPE AITRKRRLVI SDDEDD // ID G8BQ39_TETPH Unreviewed; 1245 AA. AC G8BQ39; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Uncharacterized protein; GN Name=TPHA0B04510; OrderedLocusNames=TPHA_0B04510; OS Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / OS NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; OC Tetrapisispora. OX NCBI_TaxID=1071381; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5; RX PubMed=22123960; DOI=10.1073/pnas.1112808108; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Evolutionary erosion of yeast sex chromosomes by mating-type RT switching accidents."; RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE612857; CCE62120.1; -; Genomic_DNA. DR RefSeq; XP_003684554.1; XM_003684506.1. DR GeneID; 11535181; -. DR KEGG; tpf:TPHA_0B04510; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1245 AA; 142529 MW; 02D24E5EB80213D8 CRC64; MVTAGIDNGT SPHNILRARI ALLATAIGGP DYTSTLDPPP YKQGDDCLAC LKDLKRWFKL VDDQQNRWDV AMAAAEYKVF SNDLIPLLID WETKSSLASK LGKNNLNSDN AASTSIKNKI YFDKIALNCL QLMVLMTWPL IITDQSSYEQ VSGYSELKKH QLMYKKDVLT IENGKVFKAV LRLAFNVIKI DRANRTARDN TILRLVLSFL RNIIAIEPGE LSITAKKRSA KGIGSTDTLP PNVSMDDISL SSVINCFHRN KVFKLILTLG SSLSTEFDQD FINLPLLEVM FYLTKDVNQK KLFSRKKNRE FHSSTDNGTP SNTPHLSNTG VQLTTLLAKE KQLKTNVIKN TSSRHSRFGA LLSIQTPDNG RLTISGTQGL TNDIDAMKKL DSSKKWNKRI MGDKDDVIHE GLPSSLLNSQ ADVSSFDDST LKKFKDFINN FIDSSFNVLL KSVTNHFTTE QDQMVSLEQV EYLLFFAWFI KYQILRYQYN LVDNFNPIQS VFKETSFILM SSLLRTGVEQ KNWIVAHAGM IAFNQLLSLT QVSEDDVNFD EIEYIISRLF SDDRIQLLAN LPRIAEKHSI QFMKNAIELT HTILKTLQNY AGDRLLRIEG KKRGRKAMNV SLEDIRKLME RDNVGRDEAV EILSPVTTSI EINFGRVLGR YINDNTINTY LKFLERFREL EDDSIKKVIS FFHRIFVDSK DEALLFRIDL MLLFRDMLAS NGLPRSSSSR KYVDDFSKYY LTRLKKKLKV SPAWFIGILF PTLHDNEVGY YQRFGEVRRS KVNNYDGVSV SYFKPIENEN RYTEQELLNL KFGILISSLL DDGKNELVDY LIEHLAESID KFKLYATNND NGSNPPHEYL ITENENIIES TVRDKDFRAL LQLTGYKIPN NRDEKCYIPG DIDIGTLSTF LDYIKFHKAT PFETPNGKPS STYLTRPNSK TSVDENEEED GWNGNEEYDY TDASIINDND YFKELQGTNT DLSERSLSKG IAKSKKKSKQ RKSKGKNTSN NLPTFDVDGN EIKTKKSGLQ ISSKEFISDS EEDEELDPVF FENEMYMRLL LDKHNGQLPD DKYKQFTKFA EERMNNKGHL INDYSALFDG QVLDVKDLST IEYTNSHPDL SLKSRTEQIT QQLNEDDSSQ ETKNTAGILP ETEIIQDSDA ELDIPFTNND TDLSDDDMNS SSDSDDGSHK LLTTKENVKK HNLEEDNYDE QNGHHDREIK IDNELEEEEV ISTRKRQHVF IDEDD // ID G8JMD1_ERECY Unreviewed; 1258 AA. AC G8JMD1; DT 25-JAN-2012, integrated into UniProtKB/TrEMBL. DT 25-JAN-2012, sequence version 1. DT 13-NOV-2013, entry version 9. DE SubName: Full=Uncharacterized protein; GN OrderedLocusNames=Ecym_1083; OS Eremothecium cymbalariae (strain CBS 270.75 / DBVPG 7215 / KCTC 17166 OS / NRRL Y-17582) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium. OX NCBI_TaxID=931890; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 270.75 / DBVPG 7215 / KCTC 17166 / NRRL Y-17582; RX DOI=10.1534/g3.111.001032; RA Wendland J., Walther A.; RT "Genome evolution in the Eremothecium clade of the Saccharomyces RT complex revealed by comparative genomics."; RL G3 (Bethesda) 1:539-548(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP002497; AET37340.1; -; Genomic_DNA. DR RefSeq; XP_003644157.1; XM_003644109.1. DR GeneID; 11469560; -. DR KEGG; erc:Ecym_1083; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. DR SUPFAM; SSF48371; SSF48371; 4. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1258 AA; 143142 MW; 18A6B0432ECC1892 CRC64; MIQESDVKNI RLDGGVGDVL PETILKARIA LLATAIGGPD HSSEQEPPPY RLGDDCLACL KDLRRWFTLV DEKQRRWDVA RAAAEFKILV DDLIPILADW EERSAKAVKQ SRRSGGTVGD YFRNKGYYDK VALNAFQLVV WMTWPIMLTD ESSQSHIANY SDLKKHQLIY KKMLLSSNGG KVVKAAIRLA SDIIRIDRLQ RSPRDNALLR LVLNFLRNIL AIEPSEVTIS SKQRTGNRGV SAAELLPPNV SMDDISLNNV VSTFQRSKVF AFLLTISSSI NSEFDAEYVK IPLLEIIFYL TKDLSHDHLF KWLDSSESSL PATVDHQNKG SSVGHRPKVI SRAGEELNQL LVKERDLKRS QIRISSTRHS RFGGFFSIQT PDNVRLTVSN SHNILDQDAA LKTLDNRKKW NKAVRNPADI VQGVPISFLN SAASSTYVTQ ENAKCLKRYL DGFITSSFNI LFKLIADHFT TDESNHVMLN KIHFLLSYSW FLKYHRISSE KYNIIDPISV SQALQDTCYI LLPKFLRESY EQKNWAVVHA ALLAITELLM YLNQLDNPEC EDTVDDIMSR MFSDENIKLL SNIPKSASSH SPQYVRACVN LNDTIFKTIE KYERNNKTLT TKSFGRYRGG RFTAKMDSSA NEASKQGTAQ NEDQNNEESS NDDSDIEEKS TFRMAQINFQ KVLNAYIYAG TIDTYVKFLQ RYQELEGDDI KKVMRFLNYV TIDVQEETFL FRIDFIILLK DMLSPNGLDY GSKNRKYVLD FATHFMSRLK EKLKKAPSWY VNLLFPNLHD RQLGHYMRYG EHKPIIQGLR RVACPTQFKP SNDHNSLSGG QPIDFKLGIL VSTLIDEGKR DFVTQIHENF TRTLESYKEV AGKEIHERLT YPRSDFRSDM CDMKRALLFD GDIRALVLLL GYHLPFSEKE QCYMGGQYNL LELDNILSVL GKYLLIPFHT PNGLQSSSYL VRPTVPRGGI AHNDTVENLT DYPVNDSQNI KANDKLDDYS DRYFQDLERI EERLAGKKLP KGTAKAKAKA NSKKGKKSKV KQFGVNDEHL PRNIDKKLQI VSKELISDSD DEDNLLLNPI FYENEMYLRF LLDKHNGQLP ADMFAAFSRF SNERLQNGGT TVGDYSTLFN GPVPQLGDIT SHDKNGSRST SKYMLEPNTR NKFDKITNDS DLRDSPFNDD GLEGSKNIDV PLSDFEYDST SPSNSIPPTD TVSTVSVQVA SVQLPKNTKG RSYNESDSDD AVVPRKKLPR LMLSDDES // ID G8XZD7_PICSO Unreviewed; 1287 AA. AC G8XZD7; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 03-SEP-2014, entry version 9. DE SubName: Full=Piso0_005583 protein; GN Name=Piso0_005583; ORFNames=GNLVRS01_PISO0N18097g; OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / OS NBRC 10061 / NRRL Y-12695) (Hybrid yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Millerozyma. OX NCBI_TaxID=559304; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL RC Y-12695; RX DOI=10.1534/g3.111.001032; RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P., RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A., RA Straub M.-L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S., RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., RA Mallet S., Morel G., Richard G.-F., Sarkar A., Savel G., RA Schacherer J., Seret M.-L., Talla E., Samson G., Jubin C., Poulain J., RA Vacherie B., Barbe V., Pelletier E., Sherman D.J., Westhof E., RA Weissenbach J., Baret P.V., Wincker P., Gaillardin C., Dujon B., RA Souciet J.-L.; RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps RT of genome resolution following polyploidization."; RL G3 (Bethesda) 2:299-311(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FO082046; CCE87046.1; -; Genomic_DNA. DR RefSeq; XP_004195042.1; XM_004194994.1. DR GeneID; 14518077; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1287 AA; 147794 MW; 89D30FF02F6E1C38 CRC64; MPVNEGDSYD EEKYDSESQG SDLDGFIVSE KEESEESEEE YNDRIRDLTS TLKPNETLSQ KVLKAHISVL VSALGGPDHA SSVSPPPYKL GHDALACLKD IKRWVKSVDE RSKCFDVALA CFDSGLVVND LLVILCQWDK SSSKSSLRNE KMIERIKLSC LELLVLLTWP IDFSPDLSEK QRLQFTNVRK SQLVYKKHIL AYNGGQTLKS AIRLALPTIS KHKMDREPRD NAILRLVLFL LRNVINIEPV NLSVSSKVRK QLLESDNLPQ SITYDDISLN AVISCFHNNK VFTFLLTMCN AIGSEFDKET FTQSCLECIY LLVRKVNPSH LLGKAPSKQL NNTQDTSMPS NPPNAASMQL GELLKEEDKR KKKQVQNIST RHGKFGSLLS IRDSKSSYVI SGQEALLDTS SSLAKLDKTK KWNNRTTFKY DSDEYINSSY EFLNMKTTSY FKDFVEQLLV SGGFNTLSEC SSWIFAGAQD LEYIDPYEKA CYFVTIAWFF SFKRERNQYY QRQAATPPAN EDSLDYGSVG VGLSEVNFIL IVSYFRTSIA ARNWSAVHAA MVCFRELLLI SHSIFTAAEP TSVTHERSDE LNSNQDNVDR ELAEGIIRKL FTFNDFLNKL VQLPQTASKH SQDYLRVCIS TVHILLKCFE CFANEDIKLY VQTKRKVNKK MKSSLDKTVE DSMRDIIDAS DEEYEDQRIK EVSKERRLDF QATELRFFHT SVVSSYIDFL SRYEDLTYEE IKMCLSYFHR LFVGRKDLTG LFRLDFIQVL HSLRNFLPRQ TSIRNHVEEF IYYFMKKFKN AFLRFPNPIE ILFPRLESVE FKSFLGTGDI NTAIEKESKK SQPRLAKPLE FIRESFNIDE KIKILVTALY QSEKGTFASW LQTEIERIAN ELSLYGDSRE ELISTSVYEL QAPPSTFKMI INNSYCRLLL QSLGFELPYS MEEKCELNPS TSTEHLHEVS ALLSKWINNQ PVVFEDNKDA AFYLRVKEYD IGEYALYDEN DESIAFSTEP NTNGSRHNVN ELDKLDELEA ALSRNETSQG TGDLEKGVAR RKRRAPKSRR QRPDKPSSSK EVKRSRRPPK SFNILSDDEE NEAPVKSAEY VHDSDENSDE ERLNAFFERE EKLRKLLASS GGIISHEQLE QFKLAWLKIN EVSNPTEISA TSKGIDEIVT SMMNNNRNGP TQRERTTSTS PEITNDENVR QYTPETDAEM ELEKIRNSRY PNDSSEANDL SDSSDNDGSD NQPASRHERV KQRRNTSLLD SDSDEEQSED MHNNKKKRRV VLSDDEF // ID G8Y2D0_PICSO Unreviewed; 1288 AA. AC G8Y2D0; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 03-SEP-2014, entry version 10. DE SubName: Full=Piso0_005583 protein; GN Name=Piso0_005583; ORFNames=GNLVRS01_PISO0M17854g; OS Pichia sorbitophila (strain ATCC MYA-4447 / BCRC 22081 / CBS 7064 / OS NBRC 10061 / NRRL Y-12695) (Hybrid yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Millerozyma. OX NCBI_TaxID=559304; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4447 / BCRC 22081 / CBS 7064 / NBRC 10061 / NRRL RC Y-12695; RX DOI=10.1534/g3.111.001032; RA Leh Louis V., Despons L., Friedrich A., Martin T., Durrens P., RA Casaregola S., Neuveglise C., Fairhead C., Marck C., Cruz J.A., RA Straub M.-L., Kugler V., Sacerdot C., Uzunov Z., Thierry A., Weiss S., RA Bleykasten C., De Montigny J., Jacques N., Jung P., Lemaire M., RA Mallet S., Morel G., Richard G.-F., Sarkar A., Savel G., RA Schacherer J., Seret M.-L., Talla E., Samson G., Jubin C., Poulain J., RA Vacherie B., Barbe V., Pelletier E., Sherman D.J., Westhof E., RA Weissenbach J., Baret P.V., Wincker P., Gaillardin C., Dujon B., RA Souciet J.-L.; RT "Pichia sorbitophila, an interspecies yeast hybrid reveals early steps RT of genome resolution following polyploidization."; RL G3 (Bethesda) 2:299-311(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; FO082047; CCE85941.1; -; Genomic_DNA. DR RefSeq; XP_004196136.1; XM_004196088.1. DR GeneID; 14519144; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1288 AA; 147658 MW; 8300AE94FA30AA88 CRC64; MPVNEGDQYD EEKYDSESQE SDLDGFIVSE KEESEESEEE YNDRIRDLTS TLKPNESLSQ KVLKAHISVL VSALGGPDHA SSVSPPPYKL GHDALACLKD IKRWIKSVDE RSKCFDVALA CFDSGLVVND LLFILCQWDK SSSKSSFRNE KMIERIKLSC LELLVLLTWP VDFSPDLSEK QKLQFTNVRK SQLVYKKHIL AYKGGQTLKS AIRLALPTIS KNKMDREPRD NAILRLVLFL LRNIINIEPV NLSVSSKVRK QLLESDNLPQ SITYDDISLN AVISCFQSNK VFTFLLTMCN AIGSEFDKET FTQSCLECIY LLVRKVNPSY LLGKAPSKQS YNTPDTSMPS NPPNAASMQL EELLKEEDKR KKKQVQNIST RHGKFGSLLS IRDSKSSYVI SGQEALLDTS SSLAKLDKTK KWNNRTTFKY DSDEYINSSY EFLNMKATSY FKDFVEQLLV SGGFNTLSEC SSWIFAGAQD LEYIDPYEKA CYFVTIAWFF SFKRERNQYY QKQSATPPAN EDSLDYGSVG VGLSEVNFIL IVSYFRTSIA ARNWSAVHAA MVCFRELLLI SHSIFTAAKP AGVTHEQSDE VSPNQDNVDR ELAEGIIRKL FTFNDFLNKL VQLPQTASKH SQDYLRVCIS TVHILLKCFE CFANEDIKLY VQTKRKVNKK MKSALDKTVE DSMRDIIDAS DEEYENQRIK EVSKERRIDF QATELRFFHT SVVSSYIDFL SRYEDLTYEE IKMCLSYFHR LFVGRKDFTG LFRLDFIQVL HSLRNFLPRQ TSIRQHVEEF IYYFMKKFKS AFLRFPNPIE ILFPRLESVE FKSFLGTGDI NTAIEKDSKK SQPRLAKPLE FVRESFSIDE KIKILVTALY QSDKGNFASW LQTEIERIAN QLSLYGDSRE ELISTNVYEL QAPPSTFKMI INNSYCRLLL QSLGFELPYS MEEKCELNPS TSIEYLREVS ALLSKWINNQ PVVFEDNKDA AFYLRVKEYD IGEFALYDEN DESIAFSTEP NTNGSRHNIN ELDKLDELEA ALSRYETTQG TGNLEKGVAR RKRRAQKSRS KQKPDMSSTS KEVKRSRRPP KSFNILSDDE ENEAPVKSAE YVHDSDENSD EERLNAFFER EEKLRKLLAS SGGIISHEQL EQFKLAWLKI NEVTNPTDIS ATSKDIDKIV TSMMNNNHSG PTQSEKPSSA SSATLSNENI RQDTPETDTR MDVEGIRNSR YPDDSPEAND LNDTSVSDIS NDQPISHRER AKQGRNTSLL DSDSDEEQPE DMQINKKKRR VVLSEDEL // ID G8ZQM4_TORDC Unreviewed; 1215 AA. AC G8ZQM4; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Uncharacterized protein; GN Name=TDEL0C06220; ORFNames=TDEL_0C06220; OS Torulaspora delbrueckii (strain ATCC 10662 / CBS 1146 / NBRC 0425 / OS NCYC 2629 / NRRL Y-866) (Yeast) (Candida colliculosa). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Torulaspora. OX NCBI_TaxID=1076872; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 10662 / CBS 1146 / NBRC 0425 / NCYC 2629 / NRRL Y-866; RX PubMed=22123960; DOI=10.1073/pnas.1112808108; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Evolutionary erosion of yeast sex chromosomes by mating-type RT switching accidents."; RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE616744; CCE91511.1; -; Genomic_DNA. DR RefSeq; XP_003680722.1; XM_003680674.1. DR GeneID; 11501929; -. DR KEGG; tdl:TDEL_0C06220; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1215 AA; 138782 MW; FBF42CFB3F98599B CRC64; MTDIHEYSGD NPLTILKARI ALLATAIGGP DYTSHLEPPP YKLGDDCLAC LRDLKRWFKL VDDQQNRWDV AMACAEYCIL IDDLLPILID WENKCSLAAK LARKGQSQDF KSSAVRNKEY HDSIALNCLQ LIVLMTWPLI LTEQSPAHQV SLYTDLKKHQ LSYKRHILTS ENGKALKAAN RLAFNILQID KLERTPRDNM ILRLVLNFFR NLLAIEPGEL TISSKQHSST RGINTTDMLP PGVSMDDISH NAVVSAFQRN KVLALLLTLA SSSSSEFDQE FITIPLMEVM FYMVKEIDPK ALIRNDPQKC GPDTSKEEHY SPVGLQLTEL LEKERRLKKI VVQNTSTRHS RFGALLSIQT ADHKRLTVSG GQNLLDDTSA LRKLDNSKKW SKRLPIKQDE ASNKGLPNSL LNSQGKSFHF RKETLKHFIK FIENFLESGF NPLLHRITNH FTTEQDQMVI LEQIQYLFYY SWFLRYYREV YGKHNESDDA PVSMAVKETS FILVSSLLRK GYEEKNWAVA HAGMIAFNEL LLLINNPAFK ESEDVEFILS RLLSDNRLQL LANLPKSALK HSMPFIRSSI HLTHTALKTF EAYDDDANIM VSKKTKSRDN DNTSQADIEN LMESEQIDRD EAIEILTSNI KDYSINFQKV QRYYMNEPMI DTYISFLQRY MELEDEDLKK GIHFLHRVLT LDTEQSLLFR IDLIVLLRDM LSSEGVPRTS PVRKHIEKLS DYYLHKIKKK LKSSPAWFVG ILFPLLHDSE VGFFQKYGEA KIIKKNAFYA VPPSRFKRIE DEEQLPDLHV VAMHYGIVVS ALLDEGKQDL VDQLVEHLKV ILSNVQPTST ILRDEERLPR SAMELSLRED IEKDSLFFDK DFRAILKLVG YHLPLTVKES CYLPAEIEIA KLKESLNHIT KYLTTPFETP NGLPSSSYLI RPKADRNIGQ EEQDGWVSNE DYELNEPGIV NDDDEDALAD DNGYFNELLG DTYNKSNESN LARGMAKTKK KSKDKKKKPK KRSRNTLPTF EVGDNHVKHD RALVSSKEII SDSEDEDVVN PVFFENEMYM RFLLDKFGGQ LPDEKYSRFG KFAAERMANN GDINSDFTDL FGGPVPQISS LQQVDASSTG PGKTLISLSD RISAQIEADP DSQTDINDDE QSIKIRDTIN GFGSPTGEEN MSQKYTSAGE LPVEDDSSVD LNDEQDAGDF VVKKRRKVFV EDDDE // ID G9M9V8_9INSE Unreviewed; 1209 AA. AC G9M9V8; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 18-SEP-2013, entry version 5. DE SubName: Full=TIMELESS; GN Name=tim; OS Thermobia domestica (firebrat). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Thysanura; Lepismatidae; Thermobia. OX NCBI_TaxID=89055; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=22476773; DOI=10.1177/0748730411435997; RA Kamae Y., Tomioka K.; RT "timeless is an essential component of the circadian clock in a RT primitive insect, the firebrat Thermobia domestica."; RL J. Biol. Rhythms 27:126-134(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB644410; BAL27710.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1209 AA; 137009 MW; C87B93F8BE2FC15D CRC64; MEWMEVNPEI RNTFASLGVY IGDSYHTNED CLVSLGEILS KLSVETGPPN FRRSLGFSQV IEKELLPLLI HVKDDPKIIN AAVRLLVNLT IPVECLLPIE AMSRTEAGRN TIFELSKLLI CAKEAFTDPR STRAILDHMK GILDKENLSV EDCETINNCL LLLRNILHIP EYRTGGSPGA SGSYCSKQNQ ILWDLFTQNV DKLLIHLMSC PHKSNWGVTM VQLIALAYKD QHVGTLHKLL NLWLESSLSE SSEDNESNTS PPDQGSGDSS PMLTSDPTSD SSDTGGSRNG NGNGGNTFAH KVDSENKLQN GENSGKQNNW TSSHGDYNKN IPKGDLEVSK KSQNKSPKPV KNCSKKDRQS DADSGVSSMA SLSLQSSSES RMNHFQHTSN WHCENSSGQK RECTSSEVSD CGYSTQLENQ ESISTSSNED EGPHAKRNVK LVHQKPHTMV QKARPAKPIQ TQQDKNESRR KKLVKRSRTN IMNMKALLHH VPSDEDISNL LKEFTVDFLL KGYGCLVQEL HSQLLNPKQI IQVDTSHFFW LVTYFLKFAT QLELELEHIS PVLSFEIISY LTYEGVNLCE QLEVATRHPG SDLKPFLRRM HLVVTAIRGF IQAVETYRKI SHLSKEDREY LVQLQLQIGS TDDLKCLFVL LLHQFNPNLQ SRQYLKDLII TNHMLLLLLE NVGKLPGYRG NIDIMEHIKQ FASIEVMHQY GLLLEDFQNN GEFTNDCIFT MMHHIAGDLS QVETLFQPVI LRVFSQIWEM EFEICDDWAD LVEYVINKFM SSTRHTPLPP RLFPAQLRPE EVEDGKKTKD AGRSKEDMEN LYWYFMHGAK NADCVEQVVK LYSDNGTTNR ARMDNCDDQK MYPQESSTKN SPKQPCVMMD CSENGIETND GAKNTSQTSD EITLLXEHLL KENKGREIMW LQQQLLEACY VKLNQEHKEC KKSIPIMEPI PYHYSLMKQS IPLVQWNSDQ KSIFMYQPFI LLLHKLGFHL PADVGKVFVR IPNFWTSDVL FSVAQKLGPI NSSQLKFDAN FSRVRDEPNI KATVEESELS DTPFSVLKSK QSSSAIRFMP FAQCNFKLAS FVVQPQVCSQ SYVQPGPSHQ STISRLISPT IPPIKISEAI APEMRNFLSP EPLVSQSTNG IPEDQEDAEL TPELNSIGSA DESVASDLTR MYVSDEEKCD VLPTHRTFRL IKVWIYHNIC CVLKIMCES // ID G9MDS5_HYPVG Unreviewed; 1135 AA. AC G9MDS5; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Uncharacterized protein; GN ORFNames=TRIVIDRAFT_33916; OS Hypocrea virens (strain Gv29-8 / FGSC 10586) (Gliocladium virens) OS (Trichoderma virens). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae; OC Trichoderma. OX NCBI_TaxID=413071; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Gv29-8; RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40; RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A., RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A., RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., RA Antal Z., Atanasova L., Cervantes-Badillo M.G., Challacombe J., RA Chertkov O., McCluskey K., Coulpier F., Deshpande N., von Dohren H., RA Ebbole D.J., Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F., RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R., RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E., RA Lucas S., Lubeck M., Lubeck P.S., Margeot A., Metz B., Misra M., RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E., RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S., RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M., RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.; RT "Comparative genome sequence analysis underscores mycoparasitism as RT the ancestral life style of Trichoderma."; RL Genome Biol. 12:R40-R40(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABDF02000001; EHK27234.1; -; Genomic_DNA. DR EnsemblFungi; EHK27234; EHK27234; TRIVIDRAFT_33916. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1135 AA; 130923 MW; D2E4ACF0B4AECDAE CRC64; MDLGDGTTDI VHPEVRAHIS SLIAALGGAG TEDDGRYHLG DDALEVLRDI KRWIRFYDEK TNRMDVARCI HEANLIEGDL LPILATWPEN ATDSKYKSKI ALSCFEIMVP LTWPMERDKE RMTVNHHRHM PVLELAQVQY KRAIINFDEA RILHAAVRTA LPSLALPAGD RAARDQGIIK LVLFFLRNMA MIAPPPNVQY EGDETQISRS ATIDAFSYQD IFLFLLTLAS NMGDDFRTED TAVMEIIYHL IKRVDIEKLF MTEQQVHKAK ANELASLMNK ESAMHKAYAR NGPTRHNRFG TMIWVKREDG KMSSLSGQDA LSDATARNLK MDNNKVFKPP RRTRKENKDE RDLGPPAKLN ARAAGQLRSF VEEFLDSGFN PLFQHVRKTI DREASHVMQY HRRQFFYLVA WFLEAERTRK KLKKGSGDKA DDDVSSFSLV AGVLNQEMFI TLNKAMHEAY EYKDWHELAA VMRCFTQILL TVQEMSESGR EDDEEIAENV LSRLFYEETT HDTIANIIRT YKDQGFYYLD AATELVHHFL RILEAYSKQN ADMQVRSRKR TRQKKNKDQQ QQQQQGTEDG ALAEENDDSA NDEETTERTS KERKFDFQRF AARFAPQGVV DTFIKFTRFY RDMNDAQLKR VHRYFYRLAF KQEMSVMLFR VDIIHLLYNM IKGPEPLDKS SSMYKDWEEL VKQILRKCFK KIEQRPELII EMLFSKLQST AFFLEYGYEK QTVSKKQAKP GAELVFKYTE ERDRQIAIVV GALLDKNEGD HISWVKGVIT EAESERRSWA AAEEALASTE NPFEESTDAN EPKEPSKPPP FNVRPDSDAR RTARFKDPYL RLLLNLCGFQ LFGPAAEETP ESLWVLPEDV TADSLKDTLH FINQAEFNPP TFDDGQLAEN QLKRKTLPRK KADFDDDEGD DIDDEFLFEP GGPTARKVID ESERPKKTRK RRRRNSQVQE LDDEELEEKA RKRREREREK ARKIKSAVYV KDGDDEFDEE EDEAFFARER EIAARAAKAA QSALDPEPAK KRKGAAVRID SDEEDDDDAL GLIDDEEPES RDDTPMEESD GDSRKKRRIS VEDDADEDVD MEDASNAEQS QQVEENAKED GDDAPIVARR PRIRGGFVID SDDEE // ID G9P7X7_HYPAI Unreviewed; 1150 AA. AC G9P7X7; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 13-NOV-2013, entry version 4. DE SubName: Full=Putative uncharacterized protein; GN ORFNames=TRIATDRAFT_287106; OS Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma OS atroviride). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Hypocreaceae; OC Trichoderma. OX NCBI_TaxID=452589; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 20476 / IMI 206040; RX PubMed=21501500; DOI=10.1186/gb-2011-12-4-r40; RA Kubicek C.P., Herrera-Estrella A., Seidl-Seiboth V., Martinez D.A., RA Druzhinina I.S., Thon M., Zeilinger S., Casas-Flores S., Horwitz B.A., RA Mukherjee P.K., Mukherjee M., Kredics L., Alcaraz L.D., Aerts A., RA Antal Z., Atanasova L., Cervantes-Badillo M.G., Challacombe J., RA Chertkov O., McCluskey K., Coulpier F., Deshpande N., von Dohren H., RA Ebbole D.J., Esquivel-Naranjo E.U., Fekete E., Flipphi M., Glaser F., RA Gomez-Rodriguez E.Y., Gruber S., Han C., Henrissat B., Hermosa R., RA Hernandez-Onate M., Karaffa L., Kosti I., Le Crom S., Lindquist E., RA Lucas S., Lubeck M., Lubeck P.S., Margeot A., Metz B., Misra M., RA Nevalainen H., Omann M., Packer N., Perrone G., Uresti-Rivera E.E., RA Salamov A., Schmoll M., Seiboth B., Shapiro H., Sukno S., RA Tamayo-Ramos J.A., Tisch D., Wiest A., Wilkinson H.H., Zhang M., RA Coutinho P.M., Kenerley C.M., Monte E., Baker S.E., Grigoriev I.V.; RT "Comparative genome sequence analysis underscores mycoparasitism as RT the ancestral life style of Trichoderma."; RL Genome Biol. 12:R40-R40(2011). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABDG02000027; EHK41664.1; -; Genomic_DNA. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1150 AA; 131773 MW; 9B48914C0331E58F CRC64; MELADGTTDI VHPEVRAHIS SLIAALGGAG SEDDGRYHLG DDALEVLRDI KRWIRFYDEK TNRMDVARCI HEANLIEGDL LPILATWPEN ATDSKYKSRI ALACFEVMVP LTWPMERDKE RMTINHHRHM PVLELAQVQY KMAIINFDEA RILHAAVRTA LPSLALPAGD RTARDQGIIK LVLFFLRNMA MIAPPPNVQY EGDETQISRS ATIDAFSYQD IFLFLLTLAS NMGDDFRTED TAVMEIIYHL IKRVDIEKLY MTDQQVHKAK AHELTSLMNK ESAMLKAYTR NGPTRHNRFG TMIWVKREDG KMSSLSGQDA LADTTARNLK MDKNKVFKPP RRTRKENKDE RDLGPPAKLN ARATGQLRSF VEEFLDSGFN PLFLHVRKTI DREASHVMQY HRRQFFYLVA WFLEAERTRQ KMKRDSRRSN DDVSSFSLVA GVLNQEMFIT LNKAMNEAYE YKDWHELAAV MRCFTQILLT VQEMIESGRE DDEEIAENVL SRLFYEESTH DIIANIVRTY KDQGFYYLDA ATELVHHFLR ILEAYSKQNA DMQVRSRKRT RQKKNKDQQQ QGTEDGVLAE ENDDSANDDE TAERTSKERK FDFQRFAARF TPQGVVDTFV KFTRFYQDMD DSQLKRVHRF FYRLAFKQEM SVMLFRVDII HLLYNMIKGP EPLDKGSGMF KDWEELVKQI LRKCFKKLEQ RPELLIEMLF SKLQSTAFFL EYGYEKQTAS KKQAKPGGEL IFKYTEERDR QIAIVVGALL DKNEGDHINW VKSILTAAES ERRSWAAAEE VLASTETPLE EPTDANAPKE PSKPPPFNVR VDNDARRAAR FKNSYLRLLL SLCGIQLLGP ANEETPESLW IVPGDVTSDE LKDTLHYINQ AEFSPPTFDD GQLAENQLKR KLPPRKKADF DDDEDEDVDG EFLFEPGGPT ARKAVDESER PKKTKKRRRR NSQVLELDDE ELEEKARKRR EREREKARKI KSAVYVREGD DDFDEEEDEA FFAREREIAA RAAKAAQSAV EPAVAKKPIK RKSAVQVDSD DEGEGEDDDD LLLGGLIDDD EEAEGNTSGD NTPAEESDGS GSGSGRKRRK VSVEEDDVDA EGDDDVDMED ASQAQQSGAK VAEEGDDAPV VVTRRPRVRG GFVIDSDDDE // ID H0GM61_SACCK Unreviewed; 1238 AA. AC H0GM61; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 09-JUL-2014, entry version 4. DE SubName: Full=Tof1p; GN ORFNames=VIN7_4006; OS Saccharomyces cerevisiae x Saccharomyces kudriavzevii (strain VIN7) OS (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=1095631; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=VIN7; RX PubMed=22136070; DOI=10.1111/j.1567-1364.2011.00773.x; RA Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H., RA Pretorius I.S., Egholm M., Chambers P.J.; RT "The genome sequence of the wine yeast VIN7 reveals an allotriploid RT hybrid genome with Saccharomyces cerevisiae and Saccharomyces RT kudriavzevii origins."; RL FEMS Yeast Res. 12:88-96(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AGVY01000043; EHN05153.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1238 AA; 141184 MW; DDBFE48C01E0FA10 CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVQYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEDDI TKLIKEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KSLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGVL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RYQKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD // ID H0UYB9_CAVPO Unreviewed; 1196 AA. AC H0UYB9; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 14-MAY-2014, entry version 12. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Cavia porcellus (Guinea pig). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; OC Hystricognathi; Caviidae; Cavia. OX NCBI_TaxID=10141; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=2N; RX PubMed=21993624; DOI=10.1038/nature10530; RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., RA Washietl S., Kheradpour P., Ernst J., Jordan G., Mauceli E., RA Ward L.D., Lowe C.B., Holloway A.K., Clamp M., Gnerre S., Alfoldi J., RA Beal K., Chang J., Clawson H., Cuff J., Di Palma F., Fitzgerald S., RA Flicek P., Guttman M., Hubisz M.J., Jaffe D.B., Jungreis I., RA Kent W.J., Kostka D., Lara M., Martins A.L., Massingham T., Moltke I., RA Raney B.J., Rasmussen M.D., Robinson J., Stark A., Vilella A.J., RA Wen J., Xie X., Zody M.C., Baldwin J., Bloom T., Chin C.W., Heiman D., RA Nicol R., Nusbaum C., Young S., Wilkinson J., Worley K.C., Kovar C.L., RA Muzny D.M., Gibbs R.A., Cree A., Dihn H.H., Fowler G., Jhangiani S., RA Joshi V., Lee S., Lewis L.R., Nazareth L.V., Okwuonu G., RA Santibanez J., Warren W.C., Mardis E.R., Weinstock G.M., Wilson R.K., RA Delehaunty K., Dooling D., Fronik C., Fulton L., Fulton B., Graves T., RA Minx P., Sodergren E., Birney E., Margulies E.H., Herrero J., RA Green E.D., Haussler D., Siepel A., Goldman N., Pollard K.S., RA Pedersen J.S., Lander E.S., Kellis M.; RT "A high-resolution map of human evolutionary constraint using 29 RT mammals."; RL Nature 478:476-482(2011). RN [2] RP IDENTIFICATION. RC STRAIN=2N; RG Ensembl; RL Submitted (JAN-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAKN02014837; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSCPOT00000002370; ENSCPOP00000002124; ENSCPOG00000002338. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1196 AA; 137812 MW; ABB8C8765BF82D5A CRC64; MDLYMMNCEL LATCSALGYL EGDAYHKEPD CLESVKDLIR YLRYEDETRD VRQQLGAAQI LQSDLLPILA QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSMRHHF LQVLTYLQAY KEAFASEKTF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKRID DDASVHDQLL WAIHLSGLDD LLLFLASSPA EQQWSLHVLE IISLMFRDQN PEQLARVGQG RLAQERSADV AELEMLRQRE MAEKKARALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLQNYSSD LGKQPRRIPK RHQAAQELST QHRSALNVRL FLRDFCSEFL ENCYNRLMGA VKDHLLREKA QEHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRSFHF IEKNLTNYYE MMLTDRKEAR SWACRMHLAL KAYQELLATV NEMDMSPDEA VRESSRIIKN NIFYMMEYRE LFLTLFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLMVQRDNN EEKRLHSPAI VSDQTVASGN VSYSAEELEA LWQGLAEQLQ CCTQDPELSV DSMVPFDAAS EIPVEEQRVE AMVRIQDCLL AGRASQALSL LRSAREVWPE GDVFGFPNIS PEEEMQLLKQ ILSAPLPRES IPLQLPCFRQ QELQVVQVSE KEFNFLDYLK RFACSTIVRA YVLLLRSYQQ NSAHTNHCVV KMLHRLAHDL KMEALLFQLS VFFLFNRLLS DPAAGAYKEL VTFAKYILSK FFALATVNEK AFVELLFWKN TAVVREMTEG YGTLDGRSSS CRAAAWGPEE EAQLRELYLT HKDVEGQDVV EAILAHLNTA RTRRQVIHHL VRLGLANSVK DFQRKGTHIV LWTEDQEQEL QRLFEEFQDS DDVLGHIMKN ITAKRSRARI VDKLLALGLV AERRELYKKR KKKLAPSSTP DGEDSPKDFQ QDLEDEEDLP EEESEEEDEK DEFLEGEQAH GHCVLSAASL GQDLRQEGFS VPLLWLQNCL LRAADDREED GCSQAVPLVP LTEENEEAME NEQFQQLLRK LGIRPPASVQ ETFWRIPAKL SPTQLRRVAA SLSQSKEEEE KLQPELRLSI NGEQGPSEED QQENFLLAHK KKAGLESMEE EGAAGGKEHL KVVPKKRQLL DSDEEEEGDE GRSKVPELQA PVIPKKKRYQ IEDEDE // ID H0X7S3_OTOGA Unreviewed; 1215 AA. AC H0X7S3; DT 22-FEB-2012, integrated into UniProtKB/TrEMBL. DT 22-FEB-2012, sequence version 1. DT 14-MAY-2014, entry version 7. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=TIMELESS; OS Otolemur garnettii (Small-eared galago) (Garnett's greater bushbaby). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; OC Lorisiformes; Galagidae; Otolemur. OX NCBI_TaxID=30611; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RG The Broad Institute Genome Sequencing Platform; RA Di Palma F., Johnson J., Lander E.S., Lindblad-Toh K., Jaffe D.B., RA Gnerre S., MacCallum I., Przybylski D., Ribeiro F.J., Burton J.N., RA Walker B.J., Sharpe T., Hall G.; RT "Version 3 of the genome sequence of Otolemur garnettii (Bushbaby)."; RL Submitted (MAR-2011) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (JAN-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAQR03076926; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAQR03076927; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAQR03076928; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAQR03076929; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AAQR03076930; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSOGAT00000012813; ENSOGAP00000011481; ENSOGAG00000012808. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1215 AA; 140077 MW; 4ABE6EECE28D0310 CRC64; VDLYMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFWHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASVHDQLL WAIHLSGLDD LLLFLASSPA EQQWSLHVLE IISLMFRDQN PEQLARVGQG RLAQERSTDV AELEVLRQRE MAEKKNRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLQNYSTD LGKQPQRVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR ASSFQPALVS ETLSVRTFHF IEQNLTKYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMSPDEA VRESSRIIKN NIFYVMEYRE LFLTLFRKFD ERCQPRSFLC DLVETTHLFL KMLERFCRSR GNMVVQSKRK KRKKKKKVLD QAIASGNVPY NSRELEAVWP ALAEQLQCYA QASELSTVSM VPFDAASEVP VEEQRAEAMV RIQDCLLAGQ ALEALTLLRS AREIWPERDV FGSQDISPEE EVQLLRQILS APLPRQKGPE ERGAEEEEEE EEEEEELQVV QVSEKEFNFL DYLKRFACST VVRAYILLLR SYRRNSAHTN HCIVKMLHRL AHDLRMEALL FQLSVFCLFN RLFSDPAAGA YKELVTFAKY ILGKFFALAT VNPKAFVELL FWKNTAVVRE MTEGYGSLDG GPASRRAPTW SPEEETRLRE LYLTHKDVEG QDVVEVILAH LNSASRTRKQ VIHHLVHLGL ADSVKDFKRK GTHIVLWTED QELELQRLFE EFQASDDVLG NIMKTITAKR SRARIVDKLL ALGLVSERRE LYKKRQKKLA PSSLPSGEES LKDFFQDDLE EENLPEEESE EDEEKWEGSE AEQVQGSGSH FGAPEFSTKN LGQSLHQEGF SAPLLWLQNC LFRAANDREE DGCSQAVPLV PLTEENEEAM ENKQFQLLLY KLGVRPPASE QETFWRIPAK LNPCHLRRMA ASLSQPEEEK ELQPELEPKT PGEQGPSEEH GEGHRAQALK ALWLARKKKA GLASSKEEET PSRKEQLTAA PKKRQLLDSD EEQEEDEGKN GAPELRAPGL QKKKRFQIED EDESD // ID H1UXY1_COLHI Unreviewed; 1149 AA. AC H1UXY1; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 11-DEC-2013, entry version 8. DE SubName: Full=Timeless protein; GN ORFNames=CH063_05143; OS Colletotrichum higginsianum (strain IMI 349063) (Crucifer anthracnose OS fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Glomerellales; Glomerellaceae; OC mitosporic Glomerellaceae; Colletotrichum. OX NCBI_TaxID=759273; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=IMI 349063; RX PubMed=22885923; DOI=10.1038/ng.2372; RA O'Connell R.J., Thon M.R., Hacquard S., Amyotte S.G., Kleemann J., RA Torres M.F., Damm U., Buiate E.A., Epstein L., Alkan N., RA Altmueller J., Alvarado-Balderrama L., Bauser C.A., Becker C., RA Birren B.W., Chen Z., Choi J., Crouch J.A., Duvick J.P., Farman M.A., RA Gan P., Heiman D., Henrissat B., Howard R.J., Kabbage M., Koch C., RA Kracher B., Kubo Y., Law A.D., Lebrun M.-H., Lee Y.-H., Miyara I., RA Moore N., Neumann U., Nordstroem K., Panaccione D.G., Panstruga R., RA Place M., Proctor R.H., Prusky D., Rech G., Reinhardt R., RA Rollins J.A., Rounsley S., Schardl C.L., Schwartz D.C., Shenoy N., RA Shirasu K., Sikhakolli U.R., Stueber K., Sukno S.A., Sweigard J.A., RA Takano Y., Takahara H., Trail F., van der Does H.C., Voll L.M., RA Will I., Young S., Zeng Q., Zhang J., Zhou S., Dickman M.B., RA Schulze-Lefert P., Ver Loren van Themaat E., Ma L.-J., RA Vaillancourt L.J.; RT "Lifestyle transitions in plant pathogenic Colletotrichum fungi RT deciphered by genome and transcriptome analyses."; RL Nat. Genet. 44:1060-1065(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CACQ02000552; CCF32832.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1149 AA; 131200 MW; 204ABADA81527409 CRC64; MEMPDGTSDI VHPEVRAHIN SLVSALGGTS ADDDGRYKLG DDALEVLRDL KKWIRFYDEK TNRMDVARCI AGANLVEGDL LQILASWPEN DTNNKFKARV ALACFEIMVP LTWPMDRDAE RMTVNHHRHI AVLELAQVGY KQAIINFDGA QILNTAVRTA LPSMAIAIGD RTPRDQGIIK LVLFFLRNMA MITPPPGAKY EGDETQISRS TTIDAFSFQD IFAVLLMLAS NMGEDFRTED VIVMEVIYHL VKQVDIKKLF MDERQLSKAK AQELSSLMSK ETAMRSAQNR KGPTRHNRFG TMIWMQRDDG KVSTITGQDA LADSITRQKK LDESKTFKPP RRAKKGELES KDLGAPVKLN ARANAQLRTF VEDFLDAGFN PLFEHVRKSL DREAPHVLSY HRRQFMYLVA WFLEAERVRR KSKREAKKPG TADEISSFNL VAGVLNQPMF VTLTKTMHDS WEQKEWPTLT ASMRCFTQIL LTVQEMTESG NEDDQDIAEN TLSRLFYEDS THDLIANVVR QYKEQGFEYL DSATELTHHF LRILEAYSKQ NVDMQVRSRR RTRRKKKAAE NTTGVETLDG DNDDSANDEA NAERTSKERK FDFHRFTSRF TPQGVVDTFV AFTKYYRDLD DSQLKRAHRY FYRIAFKQDM SVMLFRVDIV HLLYNMIKGP EPLDRNSGMF KEWEELSKQI LRKCMRKIEE RPELVIELLF SKTNSTAFYL EYGHEKQTIS TTNPRPAAEL EFKHTEERNR QIAIVVGALL DKNQGDHIAW VKSMLQSVED ERRGWAAANE VIPSVERTEL TAEDASADEK ANLPPPFTVR PDGDARRNAV FKNSHLRLLM KLVGFERLAP TIEETPESLW ILPSQVDAEN LHESLDFINK AEFDPPVFED GSAADDQLRR KKAVRKRAEY DDDDEGDIDD GPLFEPLGPT VRKAIDAPAP KTTKRRRRRK GSEEDEEQPN DSEVEEKARK RREREREKAR KVKSEAYVHA SDDDTDEEYD REFFLREEAQ RLRMARVVEK VTLSAPTKRP AAVVLDESDD NDDDIVTLTR ATQSTQASAD ADMDAGSEEE QNGDNRTPLT MSSPSSSQDQ GTIKRRRLSP KEPSPEKGAE GQKAANADSE NNEDDAPVPA GRVRQRTRGG FVMDSSDEE // ID H2AUJ5_KAZAF Unreviewed; 1233 AA. AC H2AUJ5; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 13-NOV-2013, entry version 10. DE SubName: Full=Uncharacterized protein; GN Name=KAFR0D03970; ORFNames=KAFR_0D03970; OS Kazachstania africana (strain ATCC 22294 / BCRC 22015 / CBS 2517 / OS CECT 1963 / NBRC 1671 / NRRL Y-8276) (Yeast) (Kluyveromyces OS africanus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kazachstania. OX NCBI_TaxID=1071382; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 22294 / BCRC 22015 / CBS 2517 / CECT 1963 / NBRC 1671 / RC NRRL Y-8276; RX PubMed=22123960; DOI=10.1073/pnas.1112808108; RA Gordon J.L., Armisen D., Proux-Wera E., OhEigeartaigh S.S., RA Byrne K.P., Wolfe K.H.; RT "Evolutionary erosion of yeast sex chromosomes by mating-type RT switching accidents."; RL Proc. Natl. Acad. Sci. U.S.A. 108:20024-20029(2011). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE650824; CCF58045.1; -; Genomic_DNA. DR RefSeq; XP_003957180.1; XM_003957131.1. DR GeneID; 13882369; -. DR KEGG; kaf:KAFR_0D03970; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1233 AA; 141897 MW; 5213CD690DEB9F4A CRC64; MDVPDASKTV LRARIALLAT AIGGPDYTSS IEPPPYKLGD DCLACLKDLK RWFKLVDDQQ NRWDVAMAAA EYKIVIDDLL PILIDWENRS AQEAKIARKH RSNVDKESEM ASPFTSKNYF DKVALHCLQL LVLMTWPLIL TDQSTMNQVN NYAELKKYQL LYKKMILSMS NGKALKAVIR LALNVVKIDR LSRTPRDNVI LKLALNFFRN IIAIEPGELM ITKRKIMPRG INSVDTLPPN VSMDDISLTA VIDCFQQNKV FGFLLTLSNS LNSEFDQDFI NIPLLEIMFY LTKDLNQKYF FRTPTNKLSK GSNDSTHEPL ISAPQLELSE LLKKEQHLKM NLVKNTSSRH SRFGALLSIE TPDKVRLTVS GSQHLLNDAA ALQKLDGRKK WKKRVIQSKD DVLEEGLPNS LLNSQSDTMG LRGSTLKVFT KFINSFIDTS FNILLHSVTN HFTTEQDRLI TLEQVEYLLF FSWFLKYQNL RSMNDHATDI SAVSEALRET SFIFVSHLLR SAYELKNWIV VHAGMIAFNE LLILVGNEKS SDEDLDDIEF IISRLFGDER IQLLSNLPKT ASKHSLQYMK SCVNLTHTVL KALEQYSTND NKLIVAGKGR RRHKANITKQ DIETLMEQED IDRDEALDIL SSRLKEFEVN FKKVQASYVN DPTIDMYINF LQRYRELDHG FIKKVIAFFH RIFIQAKEET YLFRIDLIIL LRDILSMEGL ERTARVRRHV EEFSNHYLHR LKDRLKKSPA WFIGLLFPSL HDSEVGYFQR YGENKILKRE QFYGVPPSRF KNIKDAEALP KSVLKDMKFG IIVSAMIDDG KIELLEELKE HLKNTLNVFK AWLTVNVSME RETENPPNEY FKSVQEPRNP LLLDKDLRAL LLLCDYLIPM TASEKCYLPG TVEITTLEES LTLIEKYMTT SFETPNGLPS SSYLIRPQLN MSYDNPIDED GWNGHDSYDY DDPSIVRDSD VSDNDNDYFK DLDGTMDEKL RGRKVTKGLA TSKKVKHNKK RPKKNLPKHD IEQNIEEQSK KKSHQAVSSR EYISDSDDED DAMTSIFFEN ENYMRWLLDR HNGQLTDEMF KLFGKFTAER MQNHGSVTSD FSALFQGPVP SIDAIKVSTV DSLAPKTLID FSYKVTETND NANETEHSSE EEFVDKHAPS SNSIENNQLD ERQTTSKNED QQKKRPRDNE SQSSRISEDT SEELSDDGYK SEDEEGIAVV KKKSKIIFSD DDE // ID H2D5T9_AEDAL Unreviewed; 1251 AA. AC H2D5T9; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 01-MAY-2013, entry version 5. DE SubName: Full=Timeless; OS Aedes albopictus (Asian tiger mosquito) (Stegomyia albopicta). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Aedini; Aedes; Stegomyia. OX NCBI_TaxID=7160; RN [1] RP NUCLEOTIDE SEQUENCE. RA Summa K., Urbanski J.M., Zhao X., Poelchau M., Armbruster P.; RT "Cloning and Sequence Analysis of the Circadian Clock Genes period and RT timeless in Aedes albopictus (Diptera: Culicidae)."; RL J. Med. Entomol. 46:777-782(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JN559770; AEX14536.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1251 AA; 140582 MW; 98442AF2DCEA24C7 CRC64; MEWLLANPQI NSTFGSLGSH VDDVYLVNDD ALRTLEEIIC KLALEDTSLR TFRRAIGFGQ NVKNDILPLL VNAKDTEIID TTIRLLVNLT VPIECLLPVE LFSKSEIGCH TIFELNKLLI TSKEAFVEWK TTKAVVDYMK TILEKDSKLS IDNCDSINNC LLLLRNILHI PEGNSTSGPG PHLHHNSNHN TSFQNQIIWN LFTQSIDKLL IHLMSCPQRA YWAVTMAQLI ALMYKDQHIS TLQKLLNLWF ESTLSESSED NESNTSPPQQ CSGDSSPMLT SDPTSDSSDN GSGKMTSSNN KAPDEADQAT RKANDFPSQI IMARVIKSHQ MYHQSIKVIE GVSCFVKHPS CAKSVSQGEN VPSPTDSKQV KQLSIQPKQN PSASAGLNPK SEIEVSPTEA INKTTYPNDT KSFTPPSDSI STNPNAKSTT RAAETTDQTK KELGQVSQSE TSDCGYGTQA EKESISTSSN EDDGPNQKPV HQRPPPNQKQ RFNAANKSRN PTTIHEKKEL RRKKLVKRSK SNIINMKGLM HHAPSDDDIS HILKEFTVDF LLKGYGFLVQ ELHAQLLSDL QVQIDTSHFG WLVTYFLKFA SQLELDLEHI NTVLSFDIVS YLAYEGVMLC EQLEQLSREP QIDLLPCLRR IHLVVTAIRE FLQAVDTYKK SSHLTREDKD KLKLLQLQIC ATEDLRCLFV LLLRCYNPSV QSRQYLQDLI VTNHILLLLL DGVQGIAAAS NGDMLVHIKQ FATVEIMHQY GLLLEDFRDN GAFVNDCIFT MMHHVGGDLG QINVLFQPNI LKTYSQIWET EYEICDDWSD LIEYVIHKFI NTPQPSPLAS TLPEISTQLL SGINPWTQEE KDSLQWYYVQ CKQSSCLVAD ILNLFQESGN QQKTRVSIIE QLWEQDIISL TQYDDLMKVE NPGYERNVQT PAFSVASCNS GKRDDENKTP STAVDDIQVL RDRLLKENKS NMIVWLQKSL LNCCFVKLNA LSGNLYITTS LDEQDSVVVM ESVSYHCITK KQSIPVVPWN QEQFSILSYQ PFVLLLHKLG FHLPADAKKM FVRIPEFWTA DILYSIALKL GPVEQSIIKF DLNCLQKVLS MEKEVKVDPG SDNSLDSYTV LARSNKQIPV NSFTSDSNTG WLHVVMRNKN VDTARLLDMP GPSKVIDSPN VAHPNAKVAT ASATSPAKLT HDLSVIVEAS NDDEDGNDDD DGDDDDNDEV PTEDDVNDDD ALDQTEGRRC LEEHDVVSDE DDKHDIVPPI L // ID H2KQ41_CLOSI Unreviewed; 1393 AA. AC H2KQ41; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 16-MAY-2012, entry version 3. DE SubName: Full=Timeless; GN ORFNames=CLF_103167; OS Clonorchis sinensis (Chinese liver fluke). OC Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; OC Opisthorchiida; Opisthorchiata; Opisthorchiidae; Clonorchis. OX NCBI_TaxID=79923; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Wang X., Chen W., Huang Y., Sun J., Men J., Liu H., Luo F., Guo L., RA Lv X., Deng C., Zhou C., Fan Y., Li X., Huang L., Hu Y., Liang C., RA Hu X., Xu J., Yu X.; RT "The draft genome of the carcinogenic human liver fluke Clonorchis RT sinensis."; RL Submitted (SEP-2011) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Henan; RA Wang X., Huang Y., Chen W., Liu H., Guo L., Chen Y., Luo F., Zhou W., RA Sun J., Mao Q., Liang P., Zhou C., Tian Y., Men J., Lv X., Huang L., RA Zhou J., Hu Y., Li R., Zhang F., Lei H., Li X., Hu X., Liang C., RA Xu J., Wu Z., Yu X.; RT "The genome and transcriptome sequence of Clonorchis sinensis provide RT insights into the carcinogenic liver fluke."; RL Submitted (OCT-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DF142964; GAA31231.2; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1393 AA; 160968 MW; ACE2FDE0DFD50C01 CRC64; MLADPVLRYA DIQACCACLG FREDNVYKID ADAEGTVFNN TVFMFGSFKA SIRALLRYLR NEGPDCDVRR ELGRLKIVSS DLIPLLCSCT DENKILTELA IRLLMNLTQP ALVCFRQEIP KDRDLYGAYA QVDDLLKSYK KVRSVSLINL FMLPKDFANE ELFQMLHNLV GELLDRKWEE RSEEDRLLIE RILILVRNVL HIAPDPLEEK RTDEDVSVHD QLIWAMHLSG WDELLLFLGN SEDEQTFAFH TLEIISLMLR QQIPDILASA GDNSKEPSKM NDAPYLNATF TFTHFYTLRS NRFGGTYELL STPSLSERPL IYHHDITPSL DVNCSGQKVA GSHSHKETME GEVGLVDLDV GKRTFRKPKN RKPLIERSVH RRSILAVQLY LQKFCWQFLQ YCYNPLMRTA KASLTRQATQ ENDETYYLWA MRFFMAFCRV YKFRSEYLSE TLNAATFHWI YDQVMHYREV VFSDKRGGGM NRRALQASRR LELAVAAYRE FLTCVERMFR ITTSDRAPDV SAGETQEAVE DRLRIQSTAA ESIMANVFYV SEYQEVYPML IKDFNEAIQS REHLRNLIEG SHLFMSLLSE RLKSGSQTLF VRRRRVVRRR RARKAKPVKR RTGEEGEEND TPEIRKLRLE YQWSNQLVQP LIDGLERPAD TNDEGNEDPE ESRLFDATSG GSEARQLRSA IRRVQSALFA GEALTALRLA LRLWRLWPEV APISVDENDP VLSDDRTAGL NPSQLAILGA LRQIHSTEFE GTGQEYFLTK LFLEEDEDVE ADEEDADADD DDESEDNLYN EEMGIENDGD NEGVLVTTEK EVQMDFDAFL LKFAHPRIVY ALTILLADCA SNPHTTNTAV VHIMHRLAVR QKLTGSFFQL RLFYIFQQFL RNRSLSGSPE FKDLCNLIKY ILRKFFEAQQ QNNGVLIELL FFKTVKEGFE MVKGYGTFED SKKSVKWNAE LDGELIKLFE AYRNDPVPRG QDLADVLLRH LSDVTKTRRQ IVARLVFLGL ISSVKQLKQI TIHPERERRP PRPTNEADRL EWTEDEIMRL RTLVENHTGS RTLLSDIMTD LAMDYELALR QQQEMEGIGD DADPPVIPPL RSRRVIGAKL LELGFVADPD GLGRKRRRRT VGAIPHRRGT LNVDLDISTA DKLPGKRRKS RKRKDGSSDE ELHFPVEEQD AGFGSESESE PENAIPTPRF RTSLIRKDVD ESRFMRQSFW LLWKKRTLPN RKAQDMGFLR IPLVAVVCLH ENVFVYHIMT PIRKQSHIYT STKAPMQRFT NDQNWGQTRN IRTLFDRVNI DFLTWYHPLL MRLKVTMRTQ NTHSSNLLIC SLYPNPIAFP GGAIAKHRKP NDYYFYCARY GPDHTFANNI GDSVEFALSC IAVSRQFLPE RWT // ID H2MJN6_ORYLA Unreviewed; 1218 AA. AC H2MJN6; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 11-JUN-2014, entry version 11. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=LOC101171325; OS Oryzias latipes (Medaka fish) (Japanese ricefish). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; OC Oryziinae; Oryzias. OX NCBI_TaxID=8090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hd-rR; RX PubMed=17554307; DOI=10.1038/nature05846; RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., RA Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., RA Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., RA Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., RA Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., RA Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H., RA Morishita S., Kohara Y.; RT "The medaka draft genome and insights into vertebrate genome RT evolution."; RL Nature 447:714-719(2007). RN [2] RP IDENTIFICATION. RC STRAIN=Hd-rR; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSORLT00000018886; ENSORLP00000018885; ENSORLG00000015066. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1218 AA; 140384 MW; CFBFA188356B7D30 CRC64; SDLIKMNCEI LATCSALGYL EGDNYHKETD CLESVKDLIR YLRHEDDSRD VRRQLGASQI LQNDLLPLIV QFRQDKTLFD ACIRLMVNLT QPAVLCFGKV PDDPVFTHHF MEVTSHLQAY KEAFASERVF GILSETLYNF LQLDWEQRQE EDNLLIERIL LLVRNILHVP ADPCEEKKVD DDASIHDKVL WAIHMSGFDD LVKFLASAQS EQQWSMHVLE IISLMFRDQT AELLVSAGHS RSAEEKQRDL QELEALRQKE NAEKRSRTLQ RGTRHSRFGG CFVVQGLKAI GDKDVIYHRR LHKFKSYTHD EGKAVRRVPK RNQRASECKE QRRSALNVRL FLREFCVDFL ENCYNRLMYL VKENLIREQS QQHDETYYLW ALSFFMAFNR GNNFRADLVS ETMSIRAFHF IERNITNYYE MLLTDRKEAT SWSRRMHLAL KAYQELLLTV NEMDRSHDEG IRQSSNVLKS NIFYMMEFRE IFLTLLRKYD ETKQPGTYLK DLVETTHLFL RMLERFCKGR KNLVVQRKRV KRKKSHNRKK QSVAETSPEA LAETWKIVEE ELRASGFQLS ESLTGSIIPF DATSKIPLEE QRIEAMVRVQ DALLAHTGPE ALALLRAARL REVWPDGNVF GSPDVEPEEE LELLKEILHA NLPRSTAETL VEEEDDGIEF EEEELESIQV SETEFNFKDF IKKFANPSIV RPYILMLRTY SKNTPHTNHC VVRMLHRLAV DLKMDALLFQ LSVFHLFNKI LSDPAAEAYK ELVTFAKFVV NRFFSVAAQN NKAFVELLFW KNVGAVREMT EGYSKDGCVR ASERNGKKPA WSEEEEEELR KLYMEHRDSD VPDIVETLLP LLSNSSRTRR QVVTQLVRMG LVDNAKELKK QKKGTGIVLW TEDQEEELQM LFEEFKDSED VLGNIMKKLT AKRSRARVVD KLLSMGLVSE RRELYKRRRR RAPGKSSGAG MTEEEFLSGL KQDDSVDGHY DDEEDDDESG DSEEDEEQER ENSQNVGKRS QSSHVRVAGR ADVGAIVNSL VQEGMSGPLM WIQNCLNKTA NDREDDGLSQ PVPLVPLAEE NEEAMENKTF LKLLGKLGMR APANEQESFW RISEKMSPLQ LRSAAAALTP GEGKAESSEE LDGSNGPAEG AGDERGASGE QRAQALRALL LARKRKNPTK DSALRQHSKP PKREVVNESQ KREEKTSTKR SRRGLSDDEE IFISNTNE // ID H2NHQ3_PONAB Unreviewed; 1211 AA. AC H2NHQ3; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 14-MAY-2014, entry version 13. DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Pongo. OX NCBI_TaxID=9601; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Wilson R.K., Mardis E.; RT "A 6x draft sequence assembly of the Pongo pygmaeus abelii genome."; RL Submitted (FEB-2008) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; ABGA01177688; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; ABGA01177689; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR RefSeq; XP_002823445.1; XM_002823399.2. DR Ensembl; ENSPPYT00000005519; ENSPPYP00000005311; ENSPPYG00000004661. DR GeneID; 100453126; -. DR KEGG; pon:100453126; -. DR CTD; 8914; -. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1211 AA; 139004 MW; 8B21A1A4C21BF196 CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EQQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADV AELEVLRQRE MAEKKTRALQ RGNRHSQFGG SFIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQLKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDISPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKRK KRRKKKKKVL DQAIVSGNVP SSPEEVEAVW PALAEQLQCC AQNSELSVDS VVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQAVTLLR SAREVWPEGD VFGSQDISPE EEIQLLKQIL SAPLPRQQGP EERGAEEEEE EEEEEEEEEE ELQVVQVSEK EFNFLDYLKR FACSTVVRAY VLLLRSYQQN STHTNHCIVK MLHRLAHDLK MEALLFQLSV FCLFNRLLSD PAAGAYKELV TFAKYILGKF FALAAVNQKA FVELLFWKNT AVVREMTEGY GSLDDRSSSR RTPTWSPEEE AHLRELYLAH KDVEGQDVVE AILAHLNTVP RTRKQIIHHL VQVGLADSVK DFQRKGTHIV LWTGDQELEL QRLFEEFQDS DDVLGHIMKN ITAKRSRARI VDKLLALGLV AEQRELYKKR RKKLASSILP NGAECLKDFC QEDLEEEENL PEEDSEEEEE GDSEAEQVQG SLVLSTANLG QSLHQEGFST PLLWLQNCLI RAADDREEDG CFQAVPLVPL TEENEEAMEN EQFQQLLRKL GVRPPASGQE TFWRIPAKLS PTQLRRVAAS LSQPEEEQKL QPELQPEVPG EQGSDEEHCK EHQAQALRAL LLAHKKKAGL ASPEEEDAVG KGQLKAAPKK RQLLDSDEEQ EEDEGRNRAP ELGAPGIQKK KRYQIEDDED D // ID H2R1D2_PANTR Unreviewed; 1209 AA. AC H2R1D2; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 14-MAY-2014, entry version 12. DE SubName: Full=Timeless homolog; DE SubName: Full=Uncharacterized protein; GN Name=TIMELESS; OS Pan troglodytes (Chimpanzee). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Pan. OX NCBI_TaxID=9598; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16136131; DOI=10.1038/nature04072; RG Chimpanzee sequencing and analysis consortium; RT "Initial sequence of the chimpanzee genome and comparison with the RT human genome."; RL Nature 437:69-87(2005). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. RN [3] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Adipose stromal, Skeletal muscle, Skin, and Smooth vascular; RA Maudhoo M.D., Meehan D.T., Norgren R.B.Jr.; RT "De novo assembly of the reference chimpanzee transcriptome from RT NextGen mRNA sequences."; RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AACZ03086162; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AACZ03086163; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; GABC01008274; JAA03064.1; -; mRNA. DR EMBL; GABF01008134; JAA14011.1; -; mRNA. DR EMBL; GABD01009039; JAA24061.1; -; mRNA. DR EMBL; GABE01005149; JAA39590.1; -; mRNA. DR RefSeq; XP_509535.2; XM_509535.3. DR Ensembl; ENSPTRT00000050973; ENSPTRP00000042163; ENSPTRG00000022963. DR GeneID; 452431; -. DR KEGG; ptr:452431; -. DR CTD; 8914; -. DR GeneTree; ENSGT00390000015124; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0007623; P:circadian rhythm; IEA:Ensembl. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; KW Complete proteome; Reference proteome. SQ SEQUENCE 1209 AA; 138930 MW; AD0A6A6B2C48F5DD CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHHQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EEQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADF AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQYDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDISPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKQK KRRKKKKKVL DQAIVSGNVP SSPEEVEAVW PALAEQLQCC AQNSELSMDS VVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQALTLLR SAREVWPEGD VFGSQDIFPE EEIQLLKQIL SAPLPRQQGP EERGAEEEEE EEEEEEEEEL QVVQVSEKEF NFLDYLKRFA CSTVVRAYVL LLRSYQQNSA HTNHCIVKML HRLAHDLKME ALLFQLSVFC LFNRLLSDPA AGAYKELVTF AKYILGKFFA LAAVNQKAFV ELLFWKNTAV VREMTEGYGS LDDRSSSRRA PTWSPEEEAH LRELYLANKD VEGQDVVEAI LAHLNTVPRT RKQIIHHLVQ MGLADSVKDF QRKGTHIVLW TGDQELELQR LFEEFRDSDD VLGHIMKNIT AKRSRARIVD KLLALGLVAE RRELYKKRRK KLASSILPNG AESLKDFCQE DLEEEENLPE EDSEEEEEGG SEAEQVQGSL VLSNENLGQS LHQEGFSIPL LWLQNCLIRA ADDREEDGCS QAVPLVPLTE ENEEAMENEQ FQQLLRKLGV RPPASGQETF WRIPAKLSPT QLRRVAASLS QPEEEQKLQP ELQPKVPGEQ GSDEEHCKEH RAQALRALLL AHKKKAGLAS PEEEDAVGKE PLKAAPKKRQ LLDSDEEQEE DEGRNRAPEL GAPGIQKKKR YQIEDDEDD // ID H2VDN5_TAKRU Unreviewed; 1215 AA. AC H2VDN5; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 11-JUN-2014, entry version 10. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=LOC101071157; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Tetraodontiformes; Tetradontoidea; Tetraodontidae; OC Takifugu. OX NCBI_TaxID=31033; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hd-rR; RX PubMed=17554307; DOI=10.1038/nature05846; RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., RA Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., RA Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., RA Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., RA Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., RA Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H., RA Morishita S., Kohara Y.; RT "The medaka draft genome and insights into vertebrate genome RT evolution."; RL Nature 447:714-719(2007). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSTRUT00000047490; ENSTRUP00000047330; ENSTRUG00000018488. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1215 AA; 140242 MW; 9C71612E03800728 CRC64; DQIKMDCELL ATCSALGYLE GDTYHKEHDC LESVKDLIRF LRHEDDSRDV RQQLGAAQIV QNDLLPIIIQ HGQDKTLFDA CIRLMVNLTQ PAMLCFGKVP DDPVFRHHFL EVTSHLQAYK EAFASEKVFG ILSETLYNLL QLDWEQRQEE DNLLIERILL LVRNVLHVPA DPCEEKKVDD DASIHDRVLW ALHISGFDDL VKFLASAQSE KQWSLHVLEI ITLMFRDQTP DALVSAGQAR SAQQKLRDSQ ELESLRQKEH AAKRSRTFQR GTRHSRFGGS FVVQGLKSIG ENDLIYHRNL NNFKHYSHDT GKTIRRVPKK NRQAHECKDQ RRSALNVRLF LREFCVDFLE NCYNHLMYLV KERLIREQTE EHDETYYLWA LSFFMAFNRG NDFHTDLVSE TMSIRTFHFI ERNITKYYEM ILTDRKEATS WSRRMHLALK AYQELLLNLN EMDHSQDESI RQSANIIKSN IFYMMEYREI FLTLLRKYDE TKQPQSYLQD LVESTHLFLR MLERFCTGRK NLIVQIQRKR VKRKKPRAQK KPTVLEMSPE VLAETWKIVE EELRACTQLS ASVTEIAVPF DATSETPLEE QRTEAMVRVQ DAVLARLGPE ALGLLRAARE VWPEGDVFGS ADVEPEEELE LLKQILHANL PRTTEPVPEE EEEDAAELEE EELESVQVSE SEFNFLDFIK RFANPAIVRP YILLLKSYSK NTPHTNHCIA RMLHRLAVNL KMDALLFQLS VFSVFNKILS DPAAAAYTEL VTFAKYLLNR FFALTAQNNK AYIELLFWKN VGAVREMTEG YSNDSSRIRE EAGPAWTEED EEELRKLYEE HRHSEVPDIV ETLLPLLSNC NRTRRQVVIQ LVHMGLVDNA KELKKPKKGT RIVLWTEEQE QELEMLYEEF KDSDDILGNI LKKITAKRSR ARVVDKLLSM GLVSERRELY KKKSRGPRGK STGEGMTEEE FLDALTQDFP DDSVHGDEDE EEDEFESDES EEEGEEKQGG NSENGGRSRQ SLHLPGLSGP MLWLQNCLNK TAEDREEDGF SQAVPLVPLS EANEEAMENK NFRKLLRKLG IRSPANEQEI FWRIPAKINA SQLRSAAAAL TPTPEGPDGD EQPNEPPTGE SQAEEGEEEE EAAGEQRTQA LRALLLARKT PVSDLPPVSN STVESSPQEK TSKKRSRVLE DDEYSDEEDD SDGEDISVPL KRRRKILLID EDDED // ID H2VDN6_TAKRU Unreviewed; 1209 AA. AC H2VDN6; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 11-JUN-2014, entry version 5. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=LOC101071157; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Tetraodontiformes; Tetradontoidea; Tetraodontidae; OC Takifugu. OX NCBI_TaxID=31033; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hd-rR; RX PubMed=17554307; DOI=10.1038/nature05846; RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., RA Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., RA Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., RA Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., RA Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., RA Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H., RA Morishita S., Kohara Y.; RT "The medaka draft genome and insights into vertebrate genome RT evolution."; RL Nature 447:714-719(2007). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSTRUT00000047491; ENSTRUP00000047331; ENSTRUG00000018488. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1209 AA; 139742 MW; A4B76AD52FC28A8B CRC64; DQIKMDCELL ATCSALGYLE GDTYHKEHDC LESVKDLIRF LRHEDDSRDV RQQLGAAQIV QNDLLPIIIQ HGQDKTLFDA CIRLMVNLTQ PAMLCFGKVP DDPVFRHHFL EVTSHLQAYK EAFASEKVFG ILSETLYNLL QLDWEQRQEE DNLLIERILL LVRNVLHVPA DPCEEKKVDD DASIHDRVLW ALHISGFDDL VKFLASAQSE KQWSLHVLEI ITLMFRDQTP DALVSAGQAR SAQQKLRDSQ ELESLRQKEH AAKRSRTFQR GTRHSRFGGS FVVQGLKSIG ENDLIYHRNL NNFKHYSHDT GKTIRRVPKK NRQAHECKDQ RRSALNVRLF LREFCVDFLE NCYNHLMYLV KERLIREQTE EHDETYYLWA LSFFMAFNRG NDFHTDLVSE TMSIRTFHFI ERNITKYYEM ILTDRKEATS WSRRMHLALK AYQELLLNLN EMDHSQDESI RQSANIIKSN IFYMMEYREI FLTLLRKYDE TKQPQSYLQD LVESTHLFLR MLERFCTGRK NLIVQRKRVK RKKPRAQKKP TVLEMSPEVL AETWKIVEEE LRATGFQLSA SVTEIAVPFD ATSETPLEEQ RTEAMVRVQD AVLARLGPEA LGLLRAAREV WPEGDVFGSA DVEPEEELEL LKQILHANLP RTTEPVPEEE EEDAAELEEE ELESVQVSES EFNFLDFIKR FANPAIVRPY ILLLKSYSKN TPHTNHCIAR MLHRLAVNLK MDALLFQLSV FSVFNKILSD PAAAAYTELV TFAKYLLNRF FALTAQNNKA YIELLFWKNV GAVREMTEGY SNDSSRIREE AGPAWTEEDE EELRKLYEEH RHSEVPDIVE TLLPLLSNCN RTRRQVVIQL VHMGLVDNAK ELKKPKKGTR IVLWTEEQEQ ELEMLYEEFK DSDDILGNIL KKITAKRSRA RVVDKLLSMG LVSERRELYK KKSRGPRGKS TGEGMSYDSV HGDEDEEEDE FESDESEEEG EEKQGGNSEN GGRSRQSLHL PGLSGPMLWL QNCLNKTAED REEDGFSQAV PLVPLSEANE EAMENKNFRK LLRKLGIRSP ANEQEIFWRI PAKINASQLR SAAAALTPTP EGPDGDEQPN EPPTGESQAE EGEEEEEAAG EQRTQALRAL LLARKISSSC VRFTSREQQH SREEKTSKKR SRVLEDDEYS DEEDEETETN GIADSDGEDI SVPLKRRRKI LLIDEDDED // ID H2VDN7_TAKRU Unreviewed; 1195 AA. AC H2VDN7; DT 21-MAR-2012, integrated into UniProtKB/TrEMBL. DT 21-MAR-2012, sequence version 1. DT 11-JUN-2014, entry version 5. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=LOC101071157; OS Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Tetraodontiformes; Tetradontoidea; Tetraodontidae; OC Takifugu. OX NCBI_TaxID=31033; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Hd-rR; RX PubMed=17554307; DOI=10.1038/nature05846; RA Kasahara M., Naruse K., Sasaki S., Nakatani Y., Qu W., Ahsan B., RA Yamada T., Nagayasu Y., Doi K., Kasai Y., Jindo T., Kobayashi D., RA Shimada A., Toyoda A., Kuroki Y., Fujiyama A., Sasaki T., Shimizu A., RA Asakawa S., Shimizu N., Hashimoto S., Yang J., Lee Y., Matsushima K., RA Sugano S., Sakaizumi M., Narita T., Ohishi K., Haga S., Ohta F., RA Nomoto H., Nogata K., Morishita T., Endo T., Shin-I T., Takeda H., RA Morishita S., Kohara Y.; RT "The medaka draft genome and insights into vertebrate genome RT evolution."; RL Nature 447:714-719(2007). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSTRUT00000047492; ENSTRUP00000047332; ENSTRUG00000018488. DR GeneTree; ENSGT00390000015124; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1195 AA; 138216 MW; 6C1955CF4BCDE36E CRC64; DQIKMDCELL ATCSALGYLE GDTYHKEHDC LESVKDLIRF LRHEDDSRDV RQQLGAAQIV QNDLLPIIIQ HGQDKTLFDA CIRLMVNLTQ PAMLCFGKVP DDPVFRHHFL EVTSHLQAYK EAFASEKVFG ILSETLYNLL QLDWEQRQEE DNLLIERILL LVRNVLHVPA DPCEEKKVDD DASIHDRVLW ALHISGFDDL VKFLASAQSE KQWSLHVLEI ITLMFRDQTP DALVSAGQAR SAQQKLRDSQ ELESLRQKEH AAKRSRTFQR GTRHSRFGGS FVVQGLKSIG ENDLIYHRNL NNFKHYSHDT GKTIRRVPKK NRQAHECKDQ RRSALNVRLF LREFCVDFLE NCYNHLMYLV KERLIREQTE EHDETYYLWA LSFFMAFNRG NDFHTDLVSE TMSIRTFHFI ERNITKYYEM ILTDRKEATS WSRRMHLALK AYQELLLNLN EMDHSQDESI RQSANIIKSN IFYMMEYREI FLTLLRKYDE TKQPQSYLQD LVESTHLFLR MLERFCTGRK NLIVQRKRVK RKKPRAQKKP TVLEMSPEVL AETWKIVEEE LRATGFQLSA SVTEIAVPFD ATSETPLEEQ RTEAMVRVQD AVLARLGPEA LGLLRAAREV WPEGDVFGSA DVEPEEELEL LKQILHANLP RTTEPVPEEE EEDAAELEEE ELESVQVSES EFNFLDFIKR FANPAIVRPY ILLLKSYSKN TPHTNHCIAR MLHRLAVNLK MDALLFQLSV FSVFNKILSD PAAAAYTELV TFAKYLLNRF FALTAQNNKA YIELLFWKNV GAVREMTEGY SNDSSRIREE AGPAWTEEDE EELRKLYEEH RHSEVPDIVE TLLPLLSNCN RTRRQVVIQL VHMGLVDNAK ELKKPKKGTR IVLWTEEQEQ ELEMLYEEFK DSDDILGNIL KKITAKRSRA RVVDKLLSMG LVSERRELYK KKSRGPRGKS TGEGMTEEEF LDALTQDFPD DSVHGDEDEE EDEFESDESE EEGEEKQGGN SENGGRSRQS LSGPMLWLQN CLNKTAEDRE EDGFSQAVPL VPLSEANEEA MENKNFRKLL RKLGIRSPAN EQEIFWRIPA KINASQLRSA AAALTPTPEG PDGDEQPNEP PTGESQAEEG EQRTQALRAL LLARKRKNHT SDHTGGLNPQ EKTSKKRSRV LEDDEYSDEE DDSDGEDISV PLKRRRKILL IDEDD // ID H2WK29_CAEJA Unreviewed; 947 AA. AC H2WK29; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 2. DT 09-JAN-2013, entry version 6. DE SubName: Full=Uncharacterized protein; GN Name=WBGene00135902; OS Caenorhabditis japonica. OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; OC Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis. OX NCBI_TaxID=281687; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DF5081; RG Caenorhabditis japonica Sequencing Consortium; RA Wilson R.K.; RL Submitted (AUG-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RC STRAIN=DF5081; RG EnsemblMetazoa; RL Submitted (NOV-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; CJA16697; CJA16697; CJA16697. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 947 AA; 109690 MW; 7ECEE6C339B8A264 CRC64; MILETIRDII RYLREDGDEF TARIECGRHN LVEHDLVPLV KCDDLTDEEF DIAIRLMVNL CQPAIATMRG KAPENRDEWK MYWELEENLR RAKNAFTDPC FFAAIKKPID SYFIDTDYDD RDERLRLVVE RIVLLIKYVF SINPESSEGR RTRIEDNSHD RVILAFLDSG IDKTLMHIAN QRREKEFHVA ILDIFALILK EQSADILSKS NEDGISVGEK RKTEEEFRKI IENHTVKEAQ KRRSFSRFGG SYVIEGMKGI AVNSNQVVFK PIQNVAMHDF GNDRKTKKRV ARNRRPFDVG CDGHCSSLEV RKKLIDMVIR MTETCFNNLM KSAKATIFVQ GHALQRNSQI NYFFLVKFIL RFVRLSRQDE LFSRISECTG VEAFHENNVQ LTQYTEGAAS AKGVEAKSFG LKAQYALGAY TELLLIHRHI YEHTQDELEK KMARRALEHI LNQALVKMLH RIAFDLKLVV RLYQVSLFQV FQKVNEHFSS LTKELRKSSP LYELYQFGYH VLKKYFAKFA EMGGGDLALE TLFWKGPKEC FEVEYGYGSW VKNKEAEVRV WTEDMETEVR NLYDEFKVVE SADGIDVLDF IEHNLSRART RKQIAKKLIE FGLDLMGAKW RDQKTQLDSV LPVGDLQKWY DEWKSSGDGG DVIHLIQEKL AESLGTEVSR KRIIKQLAHM GVAYEKPKKE RPLPDWSEGL VEELTNLKEQ YEEIHDAENL LGVGIVRYVI KRLSEKKPTR QVERYLISLG AKVTESSKKE RRKEKKQKID DGFVNDESEE DVEVQKSDEE EEVTEPNKRK KRAVLSSDDE DDDAKEVTPK PSENKPESSA RNSENPVEKP AQQMRKTLMG LISNKTKRRA QLDSDSDSSD SSDEDEENKN EEHKKKTAIS SDDEDRKRSY MNALLTSGSV AGAVESRESS EEPEDPFTKR IEFKRRKVVL SDNEDNE // ID H2Y692_CIOSA Unreviewed; 1089 AA. AC H2Y692; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 14-MAY-2014, entry version 8. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; GN Name=Csa.3465; OS Ciona savignyi (Pacific transparent sea squirt). OC Eukaryota; Metazoa; Chordata; Tunicata; Ascidiacea; Enterogona; OC Phlebobranchia; Cionidae; Ciona. OX NCBI_TaxID=51511; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Birren B., Nusbaum C., Abebe A., Abouelleil A., Adekoya E., RA Ait-zahra M., Allen N., Allen T., An P., Anderson M., Anderson S., RA Arachchi H., Armbruster J., Bachantsang P., Baldwin J., Barry A., RA Bayul T., Blitshsteyn B., Bloom T., Blye J., Boguslavskiy L., RA Borowsky M., Boukhgalter B., Brunache A., Butler J., Calixte N., RA Calvo S., Camarata J., Campo K., Chang J., Cheshatsang Y., Citroen M., RA Collymore A., Considine T., Cook A., Cooke P., Corum B., Cuomo C., RA David R., Dawoe T., Degray S., Dodge S., Dooley K., Dorje P., RA Dorjee K., Dorris L., Duffey N., Dupes A., Elkins T., Engels R., RA Erickson J., Farina A., Faro S., Ferreira P., Fischer H., RA Fitzgerald M., Foley K., Gage D., Galagan J., Gearin G., Gnerre S., RA Gnirke A., Goyette A., Graham J., Grandbois E., Gyaltsen K., Hafez N., RA Hagopian D., Hagos B., Hall J., Hatcher B., Heller A., Higgins H., RA Honan T., Horn A., Houde N., Hughes L., Hulme W., Husby E., Iliev I., RA Jaffe D., Jones C., Kamal M., Kamat A., Kamvysselis M., Karlsson E., RA Kells C., Kieu A., Kisner P., Kodira C., Kulbokas E., Labutti K., RA Lama D., Landers T., Leger J., Levine S., Lewis D., Lewis T., RA Lindblad-toh K., Liu X., Lokyitsang T., Lokyitsang Y., Lucien O., RA Lui A., Ma L.J., Mabbitt R., Macdonald J., Maclean C., Major J., RA Manning J., Marabella R., Maru K., Matthews C., Mauceli E., RA Mccarthy M., Mcdonough S., Mcghee T., Meldrim J., Meneus L., RA Mesirov J., Mihalev A., Mihova T., Mikkelsen T., Mlenga V., Moru K., RA Mozes J., Mulrain L., Munson G., Naylor J., Newes C., Nguyen C., RA Nguyen N., Nguyen T., Nicol R., Nielsen C., Nizzari M., Norbu C., RA Norbu N., O'donnell P., Okoawo O., O'leary S., Omotosho B., RA O'neill K., Osman S., Parker S., Perrin D., Phunkhang P., Piqani B., RA Purcell S., Rachupka T., Ramasamy U., Rameau R., Ray V., Raymond C., RA Retta R., Richardson S., Rise C., Rodriguez J., Rogers J., Rogov P., RA Rutman M., Schupbach R., Seaman C., Settipalli S., Sharpe T., RA Sheridan J., Sherpa N., Shi J., Smirnov S., Smith C., Sougnez C., RA Spencer B., Stalker J., Stange-thomann N., Stavropoulos S., RA Stetson K., Stone C., Stone S., Stubbs M., Talamas J., Tchuinga P., RA Tenzing P., Tesfaye S., Theodore J., Thoulutsang Y., Topham K., RA Towey S., Tsamla T., Tsomo N., Vallee D., Vassiliev H., RA Venkataraman V., Vinson J., Vo A., Wade C., Wang S., Wangchuk T., RA Wangdi T., Whittaker C., Wilkinson J., Wu Y., Wyman D., Yadav S., RA Yang S., Yang X., Yeager S., Yee E., Young G., Zainoun J., Zembeck L., RA Zimmer A., Zody M., Lander E.; RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSCSAVT00000000849; ENSCSAVP00000000840; ENSCSAVG00000000478. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1089 AA; 126298 MW; 19E301813F60BAD4 CRC64; EMNTEIVSTC AALGYLEEDK YFKEADCLDS IKFLIKYLHN DDSTHSVRIQ LGESQILQND LIPLLTHYAD DDELFQTVLR LVVNLTQPTL LCFGGKTPKD TTMHHLFLNI VSYNQGYKDA FGTNEEIWKI LSQKVYDVLE TEWEDRRPEV GLQVERILIL IRNLLHIPPT NEDRKKISNF SSHDKIIREL HVAGIDSLII FIAGSSTEQE YSLHIIEIIC LLLKEQTAEA LGKTGKAKSA SDRQREGEEL LNLRKIEESK KKAERAKMTP WHSRFGGTFV HRGTKSISDS RDLIVHKSVR QCDKVSFDDG KTRLKKARNR RALVQDLPQC RSSLNIRKIL KEFCNHMLDS SYNVLMRAVK DRLSREKAQD HDESYYFSAM SFFLEFNRNS NFRIELISET LQLETLHYLD MQMIDYFELM GTDKQEAEAW GKRLHMALRC YHEFLMTVHQ MEQSNNPELK EAAKVILNNV FYVVEYREIF LTLLRKFDER KQTRGFLKDL VKTTHLFLKM FENYCKSKRV RVSKKKKKGK RNTTKEKTLT EEERALKWGD IQTELRDYLQ EANSENTTDI RPADVFDPTS DLSEEDQQRT AVVKIQSHLH AGRCNESVTM LRVAREVWPE KDIFGTTSMT NDEELTAMQE ICLADLTNVV GEEAEMEEEQ ESEEEEELPP PRSTEIEFNY QDYLKKFADS KIMVQYVRLL KEFDRNDDHV NHCLVKMLHR VGFSLKMYGL LFQISLFRVF QKINTSVSSR TNKEIITFAR WLISKFQEVS LENPNLFVEM LFWKNSAAEV YDVTEGYGSF SAENRKPGKS KNVWSDDDIA ELTDLYNKYK DQDIDTVDGI LSDISNDSRT RRQVCQQLVR QGFAQSLVEL KKAKGNKSLV WREDDVNELK ILVGEYRNSS DPIGNIIQMM SNKKSRPKVV EKILALGLVN DRKELYKKRA GKPKSGNARE IMHIGGEESE DDAPVPSSDE SDHTDKVEKC SNLIRDYNDL PDSDAENITW VQQSLENSLA DRRVLPDDEP VESIPLVPVS EQQESALDNY YFKKLLKTLG LQPPSNEQEQ YWRIPASLSP MMIESSIALL KPSNKRSRM // ID H3BID0_LATCH Unreviewed; 1272 AA. AC H3BID0; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 14-MAY-2014, entry version 10. DE SubName: Full=Uncharacterized protein; OS Latimeria chalumnae (West Indian ocean coelacanth). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Coelacanthiformes; Coelacanthidae; Latimeria. OX NCBI_TaxID=7897; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Di Palma F., Alfoldi J., Johnson J., Berlin A., Gnerre S., Jaffe D., RA MacCallum I., Young S., Walker B.J., Lander E., Lindblad-Toh K.; RT "The draft genome of Latimeria chalumnae."; RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AFYH01001825; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AFYH01001826; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AFYH01001827; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AFYH01001828; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AFYH01001829; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AFYH01001830; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSLACT00000021792; ENSLACP00000021651; ENSLACG00000019023. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1272 AA; 148257 MW; AD0FD88968717F20 CRC64; MDLYMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDDTRD IRQQLGAAQI LQNDLLPVIT QYHQDKQLFD TVIRLMVNLT QPALLCFGKV PQDPAFRHHF LQVVSYLQAY KEAFANEKVF GVLSEKLYDL LQLDWEQRHE EDNLLIERLL LLVRNVLHIP ADPEAEKNVD DDASVHDKVL WAIHMSGMDD LIKFLASSQT EEQWSMHVLE IVSLLFRDQN SEQLATTGQA RTTKAKENDV VELEMLRQRE IAEKKNRTLQ RGTRHSRFGG SYVVQGLKSI GDRDVVYHKK LLNFKNYSHD MGKAAHRVPK RRQAAKETEN QRRSALNVRL FLKEFCIDFL ENCYNRLMYI VKDNLIREKT QQHDETYYLW SMSFFMDFNR IHRFRPELVS ETVSIRTFHF IEQNLTNYYE MMLMDKKEAF SWSRRMHLAL KAYQELLTTV HEMDRSKEEA VRDSSKIIKS NIFYLMEYRE LFLTLFRKFD ETKQPKSFLK DLIETTHLFT RMMEKFCKSK NNIVVQTKKV KRKKRAKGHK ASAPQEKTLE ELEEVWNSLL ETLSNCVKDA GAVPEDIVPF DVTSEVPVEE QRADAMVHSC MNLVVSVCFV FTLCLFPCDR EVWPEGDVFG STQLGPEEEL QLLKQILVSN LPRQAAPEAE ETEEMGEEEL EDEEVESFQV SEREFNFLDY IKRFASCNVV KAYILLLKNY RHNTAHTNHC IVKMLHRIAY DLKMEALLFQ LSIFCLFNRI LSDPAASAYK ELVTFAKYIL SKFFVLAEKN NKVCVELLFW KNTATVQEMT EGYRKPGEED SDGKKRSKWS PAEEEELRNL YLQYRENEDA DVLDNVMANM RNKNRTRRQL ASHLVHMGLA NSVKEFKREK KGMRIVVWTE EQELELQTLF EEFRNTDDVL GNIMKFITAK RSKARIVEKL MSLGLVSDRK ELYKKRKRKG RSGGQTEEEF LNDLGLDVPE DSSEEEDEDE SEEEKLEESR TDEPNKREKE EKKSVPGGPD RALQGLVHRL RQEGLSGPLL WLQNCLNRTA DDREEDGSSQ PVPVVPLTEE NEDAMENKQF QKLLRKLGVK PPANEQESFW RIQANLSPLQ LRRTATSLSM SEMGEEEEEE VMEKEDLPGR VPSEEQRSEA LRALLLARNK KSAQPMPVSA NAREHARCAV MPSVSANARE HARYEEMRDA EEQTKRALES DSESDTDNVS EGKRTQWKPA SKRSRMIDSD DEEIERTGET DHVEPALESD PEKSPAPTKW RCQQIEEEED ED // ID H3DLL5_TETNG Unreviewed; 1121 AA. AC H3DLL5; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 11-JUN-2014, entry version 12. DE SubName: Full=Uncharacterized protein; DE Flags: Fragment; OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon OS nigroviridis). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Tetraodontiformes; Tetradontoidea; Tetraodontidae; OC Tetraodon. OX NCBI_TaxID=99883; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15496914; DOI=10.1038/nature03025; RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N., RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., RA Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., RA Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S., RA Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B., RA Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V., RA Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J., RA Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S., RA Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J., RA Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M., RA Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C., RA Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.; RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals RT the early vertebrate proto-karyotype."; RL Nature 431:946-957(2004). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CAAE01015043; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSTNIT00000021648; ENSTNIP00000021413; ENSTNIG00000018247. DR GeneTree; ENSGT00390000015124; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR TreeFam; TF312802; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 2. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 1 1 SQ SEQUENCE 1121 AA; 129581 MW; CA1DCBBDC9AF4872 CRC64; GQIRMNCELL ATCSALGYLE GDTYHKEPDC LESVKDLIRY LRYEDDSRDV RQQLGAAQIV QNDLLPLIIQ HGQDKTLFDA CIRLMVNLTQ PAMLCFGKVP DDPVFRQHFL EVTSHLQAYK ETFASEKVFG ILSETLYSLL QLDWEQRQEE DNLLIERILL LVRNVLHVPA DPCEEKKVDD DASVHDRLLW AIHISGFDDL VKFLASAQSE KQWSLHILEI ITLMFRDQTP DALVSAGQSR STEEKLRDSQ ELESLRQKEH AAKRSRTFQR GTRHSRFGGS YVVQGLRSIG ENDLIYHRNL HHFKNYTHDT GKTVRRVPKR YRQAQECKDQ RRSALNVRLF LREFCVDFLE NCYNHLMYLV KERLIREQTE EHDETYYLWA LSFFMAFNRG NGFHTDLVSE TMSIRTFHFI ERNLMKYYEM ILTDRKEATS WSRRMHLALK AYQELLLNLN EMDHSQDENI RQSSNIIKSN IFYMMEYREI FLTLLRKYDE TKQPQSYLQD LVESTHLFLR MLERFCTGRK NLMVQRKRVK RRKRRGEKKP RVAELSAEAL AETWKIVEEE LRASGFQLSA SVTEVSVPFD ATSETPLEEQ RTEAMVRVQD ALVARLGPEA LGLLRAAREV WPEGDVFGSA DVEPDEELEL LKQILHADLP IKRSSFKGQL LNLHPELEEE ELESVQVSES EFNFLDFIKR FANPAIVRPY ILLLKTYSKN TPHTNHCIAR MLHRLAVNLK MDALLFQLSV FSVFNKILND PAAAAYTELV TFAKFVLKRF FALAAQNSKA YIELLFWKNV GAVREMTEGY SKDGSGTREG KRPAWTEEEE EELRKLYEEH RHSEVPDIVE TLLPLLSNTN RTRRQVVTQL VHMGLVDTAK DLKKPKKGTR IVLWTEEQEQ ELEMLYEEFK DSDDILGNIL KKITAKRSRA RVVDKLLSMG LVSERRELYK RKSRGSRGKS AGKGMTEEEF LDALTEGFPD GSNGGRRRSL QLPAGRRVDV ASMVSALQQE GMSGPLLWLQ NCLYRTAEDR EEDGFSQAVP LLPLSEANEE AMETRSFQKL LRKIGIRAPA NEEIFWRIPA KISASQLRSA AAALTPEPEG PGGDDKQRDC GTGESQRAQA LRALLLARKR K // ID H3FS65_PRIPA Unreviewed; 402 AA. AC H3FS65; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 16-OCT-2013, entry version 8. DE SubName: Full=Uncharacterized protein; GN Name=WBGene00114690; OS Pristionchus pacificus (Parasitic nematode). OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Diplogasterida; OC Neodiplogasteridae; Pristionchus. OX NCBI_TaxID=54126; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PS312; RA Wilson R.K.; RT "Draft sequence assembly of the Pristionchus pacificus genome."; RL Submitted (DEC-2008) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RC STRAIN=PS312; RG EnsemblMetazoa; RL Submitted (NOV-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; PPA25136; PPA25136; PPA25136. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 402 AA; 46483 MW; DDCDF7F361204607 CRC64; METIVQGTIG ALGYLEDGVY YPEPDCIETV RDLIRFLRAD GPDLMVRRCC GSHNVVGSDL IPILKTPKLK DDMFDLTLRL AANLCQPSMV SLQGKTPETK EQVAMQRQLE DNLTRTKLAC ADRGLFDVLK AKLSRFFIET DWDSRTEEQR LVMERIVVFI RYMFSITPIG IDDKRTAFDT SSHDRLVEAA IDSGLDVLLM EISKDRRERD FHLSILEIFA LMLKEHKPED LVSADQGRSE EEKRKTEVEL QQIVENQRAA MEEMKRKIMG KRHTNFTGSY EVRGLTAPIS GNDRIIINKP VKDVTALEFN ETRKAKKRTP KNRRPFEANQ RTFLSSMEIR LKMKGFVTRL LEDCYVRLMR STKTAAFDAR RSIGQRQADL HYFLLERFCV QFARLAKMRA EK // ID H3H2K5_PHYRM Unreviewed; 1188 AA. AC H3H2K5; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 06-FEB-2013, entry version 6. DE SubName: Full=Uncharacterized protein; OS Phytophthora ramorum (Sudden oak death agent). OC Eukaryota; Stramenopiles; Oomycetes; Peronosporales; Phytophthora. OX NCBI_TaxID=164328; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Pr102; RX PubMed=16946064; DOI=10.1126/science.1128796; RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H.Y., Aerts A., RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J., RA Damasceno C.M.B., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L., RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., RA Huang W., Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., RA Lee M.-K., McDonald W.H., Medina M., Meijer H.J.G., Nordberg E.K., RA Maclean D.J., Ospina-Giraldo M.D., Morris P.F., Phuntumart V., RA Putnam N.H., Rash S., Rose J.K.C., Sakihama Y., Salamov A.A., RA Savidor A., Scheuring C.F., Smith B.M., Sobral B.W.S., Terry A., RA Torto-Alalibo T.A., Win J., Xu Z., Zhang H., Grigoriev I.V., RA Rokhsar D.S., Boore J.L.; RT "Phytophthora genome sequences uncover evolutionary origins and RT mechanisms of pathogenesis."; RL Science 313:1261-1266(2006). RN [2] RP IDENTIFICATION. RC STRAIN=Pr102; RG EnsemblProtists; RL Submitted (DEC-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblProtists; Phyra84621; Phyra84621; Phyra84621. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1188 AA; 134309 MW; 9AE681BDD8B4D8AB CRC64; MSSSDEDKDG NDPALDADMM NELLLVCSNL GMLRVQTEGE APVLLRGENC DDWVHDLQRA VRRDHAKHRL VTKQLGKWKI LQKKLLPLLV HHQHDWKLVF SILKVLVMLT TKPPRDSTNI AQQLKYLRQY KHEFLRCGVV PIMMTILVEP LSRKGSARTP QDFLNMEIVL TLLRNLLAIP NEDPRFVTST TSYFSHLQED FICTLHDENV YEMILLFTQD IEAPENREWN LLIMEMIDLT LDCSQPKCVV AYAKNQLTGK TSSSSSGQAA ATTTPSGARN AASAGGNLLA KLDSEKKASA LHQSGSHRHS NFGGIMKMVG PTGRATVVSD FSKTVYDQVP QAAKKPVSRR RGKKSAAPVT DIHEVFGGKG RVTESDERTM KVLQEICDSI VAKSYFQLTT SLKTEFRRGS QKLISTDRLQ YFHLVWFLTT YHRLKIQALK SHYKHQLKAV QKKTTELQNA LDFTTPPPPA PEKPDYDEKA VLSTLDMFSF NFVLQSIENY ATMKNYHGMT VAVQLLAEMM AYLAELTASD DPRFQRIADS LQHKILYERD FLDRLPVLLK TWSPGLFPKA YVVDVVTLTH VLSRRKAYLD KKRQKKKQAG GESKEGEDSD DSSTDEEETE RQAQLLMEMQ RKEADFDVRK YFSSMVSSDT IRMYCSLLTD YRENTAKLNH YIHSFFYRTK HFQIYPQEEW TMQPMLFNIH VLMLFNKILQ DTYIQRLPEY KNFLDFIRGV VRDFFTLADK NNLLFVEALL RQPYPSKSCM LIQRNYDPIE SMNKSKSEAV ALGREKRIDA INESRRHRIA LDHEELEGEA EFQFSLGPSD FQSTSLVDKE DNKDEDNASS NPSGAAKPKQ NKKTPMSRAA TERAKNWSKV EDRYLAKMFM KYRHLPSVYE VISYEDMFQE RDRTPEQIER RVKYLKLHRK THDSSDEDEN EQSHSEGEQG GEQKGEEEES TRVLRESRLE KDLAALDSAR PRRRLRRGAD LSDDDSDDEL LLGGSNPTAA NLSQPTSAVA PANEESVNAS NAADDDEMSG KSPTEDVSFT IPPVSDANAI QSQDMEETQV LEDSLDARGE GQSEQSTDAE ATQDLGASED ATDKDPRTSS LAPDSSPTQD NADGAAMETD AEHESPSVAM EAASLNDDQE QNDAAQSLKR ARSTEDAAGD AQVEDTPAKK VQRAEVEAPA ADASASQQ // ID H6BTM9_EXODN Unreviewed; 1155 AA. AC H6BTM9; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 14-MAY-2014, entry version 5. DE SubName: Full=Replication fork protection complex subunit Swi1/Tof1; GN ORFNames=HMPREF1120_03590; OS Exophiala dermatitidis (strain ATCC 34100 / CBS 525.76 / NIH/UT8656) OS (Black yeast) (Wangiella dermatitidis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Chaetothyriomycetidae; Chaetothyriales; Herpotrichiellaceae; OC Exophiala. OX NCBI_TaxID=858893; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 34100 / CBS 525.76 / NIH/UT8656; RX PubMed=24496724; DOI=10.1534/g3.113.009241; RA Chen Z., Martinez D.A., Gujja S., Sykes S.M., Zeng Q., Szaniszlo P.J., RA Wang Z., Cuomo C.A.; RT "Comparative genomic and transcriptomic analysis of Wangiella RT dermatitidis, a major cause of phaeohyphomycosis and a model black RT yeast human pathogen."; RL G3 (Bethesda) 0:0-0(2014). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JH226132; EHY55456.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1155 AA; 133133 MW; E1D2CE4B04C210DA CRC64; MEEDNPFSKS QTVHPEVRAY VYSLVNALGG SSTDDDGRYV LGDDALACLR DLKRWLKLYD EKNNKLDVAR CLAEAKLVGG DLIPILASWP EDGKENKLKA RVALACLELL VPLTWPLENG GEMTLNHHRH TPYIQQAQVL YKAGILGCET SPILRQVIRI GLPSIAVARD ERTTRDEGIL KLMLYFFRNV AVIDQIPNLP SQGLENEVSR SATIEAFRDQ DVFALLLTMC SNMGDDFNHQ DVIILDIIFN LIKGVDPKRL WMTEQERTGQ GISDLSAALA LEDSMNKDAK RNQWTRHGRF GTMLWVKREG EKVSTVTGQD NLKSDQKAFF NMDKSKKWSK PQQRRKDIDH TIHDFDHTTW LTNSASEKLR NFVEEFLDSG FNPFFSHLRK AIQREAERLQ DINYRQFFYA VAWFMEAERV RRETRKKDIK SEKIRAEFED ESYALVAAVL NQETFIMLNR YMQISWDNKE WQDLNASMRC FTQILLTVQE MAQSPLEEDQ EIADNIQNNI FYEETTHDRI VGILKSYKDQ GFGYLDACTE LSHVFLRMLE RYSKENADLQ IRSRRRARRK RKEAQRQAAQ PGDDPIMDDD EKSENEDIAD VIQVSKERKF DFNRFAAKFA SQASVNTFVS LLSFYRDLTS DQLKRAHRFL YRVAFKQDLA VLLYRVDIVA LLYKIVNGPD GLDKKNPMYR DYSELSRQLF KKMFKKIDQR PELVVEMLFS KIPATLYYLE FGHEKQTIAA SRPPVDLEIR PAPGRDVKEQ IGIVVTVLLK DGKTELVKWV KDVLGKAFDE RHSWEAEAEV RRAAALEAAQ KDNESTTDVV DIGQPSYITV RPTSDDIKTA MFKNGRLRLL MRLVGFEMLG DEDVLGASWI VPSGVTSEKL AESKLAIERY ESTPWQGDDE NEDAEDLIRR ARNKDKSTRD SGDDASAPRD AFIDDSEGEE EFLFPDNPRK KRTAKNIIEE LKARRKKRKR GDDDEDGEID EALAAQRRAE REKAARARRL KIKSEAYIRD SDDESDEEKD RLFFEREEQL RKNQAENIRK QMALDREDQA SKTQKKRKLA ATLQEESEDD LLMQDIDDGH AETASKTQEK RREVAPRQTR RIHEDSDDDL LILDIDDGHA EPASSQTLRK SDTEAEEDDE DTPLSSQSSA TVKPS // ID H6UDU4_GADMO Unreviewed; 117 AA. AC H6UDU4; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 11-JUN-2014, entry version 3. DE SubName: Full=Timeless; DE Flags: Fragment; GN Name=tim; OS Gadus morhua (Atlantic cod). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Zeiogadaria; Gadariae; Gadiformes; Gadoidei; Gadidae; Gadus. OX NCBI_TaxID=8049; RN [1] RP NUCLEOTIDE SEQUENCE. RA Kumaratunga H.P.H.S., Lazado C., Nagasawa K., Campos C., Giannetto A., RA Karlsen B.O., Fernandes J.M.O.; RT "Circadian genes in Atlantic cod."; RL Submitted (AUG-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; JN634817; AEZ03844.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 FT NON_TER 117 117 SQ SEQUENCE 117 AA; 13239 MW; D986B1AA1B20556D CRC64; TCSALGYLEG ETYHKEADCL ESVKDLIRYL RHEDDTRDIR QQLGAGHILQ NDLLPIISQH GGDQPLFDAC IRLMVNLTQP ALLCFGKVPD DPALRHHFLQ VTSYLQAYKE AFASEKV // ID H7BX89_MOUSE Unreviewed; 534 AA. AC H7BX89; DT 18-APR-2012, integrated into UniProtKB/TrEMBL. DT 18-APR-2012, sequence version 1. DT 09-JUL-2014, entry version 16. DE SubName: Full=Protein timeless homolog; DE Flags: Fragment; GN Name=Timeless; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=C57BL/6J; RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112; RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., RA She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., RA Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., RA Zhou S., Teague B., Potamousis K., Churas C., Place M., Herschleb J., RA Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., RA Lindblad-Toh K., Eichler E.E., Ponting C.P.; RT "Lineage-specific biology revealed by a finished genome assembly of RT the mouse."; RL PLoS Biol. 7:E1000112-E1000112(2009). RN [2] RP IDENTIFICATION. RC STRAIN=C57BL/6J; RG Ensembl; RL Submitted (FEB-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AC135859; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR Ensembl; ENSMUST00000105243; ENSMUSP00000100877; ENSMUSG00000039994. DR MGI; MGI:1321393; Timeless. DR GeneTree; ENSGT00390000015124; -. DR NextBio; 35562290; -. DR ArrayExpress; H7BX89; -. DR Bgee; H7BX89; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0042803; F:protein homodimerization activity; IDA:MGI. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:MGI. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IMP:MGI. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. FT NON_TER 534 534 SQ SEQUENCE 534 AA; 62561 MW; 1EE2C668C81394BC CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDSSVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKSID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQT PEQLAGVGQG RLAQERSTDV AELEVLRQRE MAEKRARALQ RGNRHSRFGG SYIVQGLKSI GEKDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLRERA QQHDETYYMW AMAFFMAFNR AATFRPGLVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDEA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLR DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKK // ID H8X0K4_CANO9 Unreviewed; 1132 AA. AC H8X0K4; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 13-NOV-2013, entry version 7. DE SubName: Full=Ybl053 protein; GN ORFNames=CORT_0B01750; OS Candida orthopsilosis (strain 90-125) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=1136231; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=90-125; RX PubMed=22563396; DOI=10.1371/journal.pone.0035750; RA Riccombeni A., Vidanes G., Proux-Wera E., Wolfe K.H., Butler G.; RT "Sequence and analysis of the genome of the pathogenic yeast Candida RT orthopsilosis."; RL PLoS ONE 7:E35750-E35750(2012). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; HE681720; CCG21893.1; -; Genomic_DNA. DR RefSeq; XP_003867331.1; XM_003867283.1. DR GeneID; 14538161; -. DR KEGG; cot:CORT_0B01750; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 1132 AA; 129380 MW; 5F44AEFF2370933C CRC64; MSDIETGSDV ENYYDAEEFD DFIDYSDEEV TEIEPPKGVE SIAGQSINTP TELNNEDGNE EEKEEEEEEE DKIRTLTTTL KPNETHAQKL LRAHIAILVS ALGGVDHTSE IKPPPYKLGH DALACLKDIK RWIRAVDEKQ NNYEVALACA ECGLIQNDII VVLCQWEQKM AKKELIKNKT SMEKIMLSCL EILVLLTWPV DFDKNLSENQ KLLYANIRKI HVLYKKHILA YNNGQLLKAV IRLVLPVLQK SKVDREPREN QILRLVLYFI RNLLAIEPAT STISSKARNA IVASADLPSG VTQDDISINH VLKVFRKNKV LMLLLTISGS INVEFDKDLF GEVTLECIYL IIKGIESKDV LVRPPPQAPS SNVSTDASAP LVPLSSTVNM QLSDLLATES KKKQAQTSKI ATRHGKFGTL LSIRSSDATS YVVSGEEALV NTDGTLDKLD KSKTWKNQNH FKYDSDDFVK TSSPVYLTAP GRQILHEFIN EFLSGGCFNN LIEVMASKLT SQSEYSTVDE LSNASYFFTI AWFLNYQREQ IVLDSTSSFD FGSVRAALSE INFILIVTYF RDSFAKKSWN SLHVAMICFK ELLKISNSIF GKKRNTIEDD TQYEIDRELA EGIIRKLFSF NDFLNILVLI PQSAFKHSPR FLKESIHVIT IILKSFESFA KEDLQLYVQT KRKQSKNNKK RINELNRDTD AKLSAAIYDS DDEAIAENIR EVTRERRLNF QATEVRFFHQ AIVTAYIEYL SRFQDLNHDD IKICLSYFHK LFVVRKDYNG LFRLDFMQML HKLKNHLPRG SSIRLKVEEF IYYFMKKFKV ALGRFPNIIE VLFPRIEESS VKCYLSTGEL YEKEDLLERK FERKFQQAET DKAYNGDDAE GGDEGDDDDI AFELAANPNS SRQNGTELDQ LDELEAQLNS QHKPRSKNLE RGKAHKRKSK LKTKPSKDQE MQPGRRRIPA GLLEESQFTR SSEFVHDSDD ESDDERHQEF FAREERLRKL LNEIGSITNN EKLEEFKKVW SVYSKNGDKE VANVVKNVVE EVSLFVEDED DDVEEAPKQT GFTKLHSDEE SNASLESDEH SASQSGPAPE HFSSNTSDMD SDTNKRTRSV DDGEQSAPIR KKRLVISDDE DD // ID H9H0Z4_MELGA Unreviewed; 537 AA. AC H9H0Z4; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 13-NOV-2013, entry version 4. DE SubName: Full=Uncharacterized protein; OS Meleagris gallopavo (Common turkey). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Testudines + Archosauria group; Archosauria; Dinosauria; Saurischia; OC Theropoda; Coelurosauria; Aves; Neognathae; Galliformes; Phasianidae; OC Meleagridinae; Meleagris. OX NCBI_TaxID=9103; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=20838655; RA Dalloul R.A., Long J.A., Zimin A.V., Aslam L., Beal K., Blomberg L.A., RA Bouffard P., Burt D.W., Crasta O., Crooijmans R.P., Cooper K., RA Coulombe R.A., De S., Delany M.E., Dodgson J.B., Dong J.J., Evans C., RA Frederickson K.M., Flicek P., Florea L., Folkerts O., Groenen M.A., RA Harkins T.T., Herrero J., Hoffmann S., Megens H.J., Jiang A., RA de Jong P., Kaiser P., Kim H., Kim K.W., Kim S., Langenberger D., RA Lee M.K., Lee T., Mane S., Marcais G., Marz M., McElroy A.P., RA Modise T., Nefedov M., Notredame C., Paton I.R., Payne W.S., RA Pertea G., Prickett D., Puiu D., Qioa D., Raineri E., Ruffier M., RA Salzberg S.L., Schatz M.C., Scheuring C., Schmidt C.J., Schroeder S., RA Searle S.M., Smith E.J., Smith J., Sonstegard T.S., Stadler P.F., RA Tafer H., Tu Z.J., Van Tassell C.P., Vilella A.J., Williams K.P., RA Yorke J.A., Zhang L., Zhang H.B., Zhang X., Zhang Y., Reed K.M.; RT "Multi-platform next-generation sequencing of the domestic turkey RT (Meleagris gallopavo): genome assembly and analysis."; RL PLoS Biol. 8:E1000475-E1000475(2010). RN [2] RP IDENTIFICATION. RG Ensembl; RL Submitted (MAR-2012) to UniProtKB. CC -!- CAUTION: The sequence shown here is derived from an Ensembl CC automatic analysis pipeline and should be considered as CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR Ensembl; ENSMGAT00000007108; ENSMGAP00000006359; ENSMGAG00000006354. DR GeneTree; ENSGT00390000015124; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 537 AA; 59802 MW; 80908FC42D3999EE CRC64; MDWYMMNCEL LATCSALGYL EGDVYHREPD CLESVKDLIR YLRHEDESRD VRQQLGAAQI LQNDLLPLLV QYPQDRTLFR CRRQRLMVNL TQPALLCFGK VPSDATARHH FLQVLSYLQA YKEAFASEKV FGVLSEKLYE VLQLDWEQRQ EEDTLLIERI LLLVRNVLHV PPDPLCGAGN GVDGDASMHD RVLWALHISG MDDLLKFLAX DGADGQRRRR PPGRAGGGSQ PPSLAPSPPQ HCLTTLSPLQ DAPGPEGVPG AAAHGAGDGP LPRASGAGQQ SAVSIRAFIH LWLCPSVHPS IYLHGPLSLR PSIHVFVRAS ISLGIHLSVP LSKRSHIRLS VHTDPASLPP PPDHIFYLME YRELLLALFR KFDETKQPRA FLRDLVETAH LFLQMLERFC RGRSGLVVQS KRVRRKKKPR VPAAPQPPGA AELEELWAAV APQLQDCLQG TVPLPEDVVP FDAASETPVE EQRAAALLRI QECLREGRAP QALRLLRSAR EVWPEGDVFG PPGAEPPEET QLLREICFAA LPRECTA // ID H9J9N3_BOMMO Unreviewed; 674 AA. AC H9J9N3; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Uncharacterized protein; OS Bombyx mori (Silk moth). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Bombycoidea; Bombycidae; Bombycinae; Bombyx. OX NCBI_TaxID=7091; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=p50T; RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004; RG International Silkworm Genome Consortium; RT "The genome of a lepidopteran model insect, the silkworm Bombyx RT mori."; RL Insect Biochem. Mol. Biol. 38:1036-1045(2008). RN [2] RP IDENTIFICATION. RC STRAIN=p50T (Dazao); RG EnsemblMetazoa; RL Submitted (AUG-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; BGIBMGA006226-RA; BGIBMGA006226-TA; BGIBMGA006226. DR OMA; THNDSES; -. DR OrthoDB; EOG7SXW2F; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 674 AA; 76418 MW; 829449B6B4B7A3CE CRC64; MEWVLRSPQI HSSFGNLGFL HADGYHVNEN CNNVLESILH NILSEDEYLR TYRRSISFGQ NVKKDLIPLL IHTKDDKTIE LLIRILVNLT IPIECLLSVD EISKNDFGRH TIFEINNLLA TTKMAFTDQR ATKVVIDFLK KNFDLEQKTM LTIEQCTNIS NSLLLLRNIL HIPEKTPTRS PTFNGPVHSI QNQIIWNIFS QSIDKVLIKL MIIPDAAKWA VTMIQFIALL YKNQHAVTLH KLLNLWLESS LSESSEDNES NTSPPDRGSD DSSPILTSDP TSDSSDTGGS GKSNDEPNSV NNGWDASSVN NTSENGSQTS QTHNDSESPR KNAENIAEGS MKDENVNEAK SVTFSESNTE ATKDVPAGED KMKAVISENS DCGYGTQIEN QESVSTSSND DELPSEKPVH QKPHNPKQRV NTKSRSGVTV QERKRKKIVK RGKSNIINVQ GLSHKTPTDD DISNILKEFT VDFLLKGYNV LVQTLHSQIL TNLQLEIDTS HFFWLVTYFL KFATQIELDL EHLCSVLSFD IVSYLTAEGV NLCEQFELAV KLDGNGLKPC MRRLHLVVTA IRELVQAIEV YKKISFIRKD DREALIKLQI KMCETDELRS LMVLLLRTYN PKYHTKQYLQ DIIVTNHILL LFLDNVMKMT EYNGTTNMVD HIKQYVVHFI QLSL // ID H9JSP7_BOMMO Unreviewed; 1251 AA. AC H9JSP7; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 13-NOV-2013, entry version 6. DE SubName: Full=Uncharacterized protein; OS Bombyx mori (Silk moth). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Bombycoidea; Bombycidae; Bombycinae; Bombyx. OX NCBI_TaxID=7091; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=p50T; RX PubMed=19121390; DOI=10.1016/j.ibmb.2008.11.004; RG International Silkworm Genome Consortium; RT "The genome of a lepidopteran model insect, the silkworm Bombyx RT mori."; RL Insect Biochem. Mol. Biol. 38:1036-1045(2008). RN [2] RP IDENTIFICATION. RC STRAIN=p50T (Dazao); RG EnsemblMetazoa; RL Submitted (AUG-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; BGIBMGA012558-RA; BGIBMGA012558-TA; BGIBMGA012558. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1251 AA; 145498 MW; C74A770118BE03FB CRC64; MSSLLSAELS ATCNALGTFD KKTGKYLIDE FTINTVKDLI RYLRRDGEDH EIRRHLGQTK VLQTDLLRML IDHWENAELF DVTLRLLVNL TNPALLLYRE EVPTERTARH NYLQILTHLQ AYKEEAFSKV DIWNVFSQKL AKILETDWSE RDEDTGLIIE RILILIRNVL HVPADLDKEK RPENDANIHD QVLWSLNQSG ILDIILYMSS ENEKQYFMHI IEIISHLLRE QNPSSLADAA LQRSVDEKLK DEQELLSLRM TENNLRLSKI KQYSATRHSR FGGTYVVQNM KSISDNEIIS LKPLNDISKL DFSGGKKSKL VKPKNRRPME SGMLERRSAF AIRLFLKEFC IEFLNGSYNS LMHYVKDVLV RAKAQQNDES YYLWAVKFFM EFNRGHNFQV GLISETMSIP MFHYVQQQME KYYDMIKVEK KKFGVWVRRL HLALRAYKEL LYTLLAMDKS TDPTVKESAK VLKSNIFYVL EYREFILNTF LNYDENKMPR SYLVDLVETV HLFLKMLEHY CKKTGLVVQK KIKKKSKSKR NKPRAQRAPP TEPGAPAWEE ARPQLAAVLS AGPEEYPPPF DAASDVPIDQ QKEDCMRNIQ KSMREYKFEN AVGMFRAARE VWPEDGIFGA SDIAEDEELS MLETIYNTDL GVVTDVTEID EVDETQGSEY EEEGKFCHPK VVSSCVSLLE RYDKNLPHTN HCAIKMLHRV AWDCKRPSMM FQASLFLIFQ KIFNNPMQQH KELEKFGIYI FRKFTEIASK NPKAFIELLF WTNSKDALDI EYGYDPYTDS RDKLGKGVWS EEQEEELRRL YMENQTNPET DQDVIDWILE NLIDRTRTRR SVIKKLKELG LIFKAPTKRS NKERARERVP KEFSPEEDEM LQELWPQYAD STDPMAFIMS RMPRKRQKKS YVERLLELGL VKDKNECRKK RQKNSEGKST RSGDDKSNDD ESSSSGSESE SDTKRTSFPS KQTAPKPRKT KNQTKAKRVE LNASQVAKLL VSAVDNGLSG ALKWLAENLE ELALDQEAEG YDPNSEGTPL VPITDESTEA MDKELFKQVL LGIGVVPPND EQESYWRIPS CLHFETIRKR REIIMRAVQR ELIIGPLNED QTEKQLHEIA VDESSNDDDL FNNLRKLRET NADTKKIIRT ETANDITKSN NRKRGRTESN QENRKQKLTK IDEDYEHELT EDSEDVLSFA KRTLQQDTPD TEEILNNISK LTSDNSGDDE DIVPMKRNSK KRRIVIEDDS E // ID H9K887_APIME Unreviewed; 623 AA. AC H9K887; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 09-JUL-2014, entry version 5. DE SubName: Full=Uncharacterized protein; GN Name=Coq7; OS Apis mellifera (Honeybee). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Apoidea; Apidae; Apis. OX NCBI_TaxID=7460; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=DH4; RA Zhang L., Deng J., Wu Y.-Q., Kovar C., Aqrawi P., Bandaranaike D., RA Blankenburg K., Chen D., Denson S., Dinh H., Firestine M., Gross S., RA Han Y., Hernandez B., Holder M., Jackson L., Javaid M., Jing C., RA Jones J., Joshi V., Kamau G., Korchina V., Lee S., Lorensuhewa L., RA Mata R., Mathew T., Mims S., Ngo R., Nguyen L., Okwuonu G., Ongeri F., RA Osuji N., Pham C., Puazo M., Qu C., Quiroz J., Raj R., Rio Deiros D., RA Santibanez J., Scheel M., Scherer S., Vee V., Wang M., Xin Y., RA Richards S., Reid J.G., Newsham I., Worley K.C., Muzny D.M., Gibbs R.; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DH4; RG Honey bee genome project; RA Zhang L., Deng J., Wu Y.-Q., Kovar C., Aqrawi P., Bandaranaike D., RA Blankenburg K., Chen D., Denson S., Dinh H., Firestine M., Gross S., RA Han Y., Hernandez B., Holder M., Jackson L., Javaid M., Jing C., RA Jones J., Joshi V., Kamau G., Korchina V., Lee S., Lorensuhewa L., RA Mata R., Mathew T., Mims S., Ngo R., Nguyen L., Okwuonu G., Ongeri F., RA Osuji N., Pham C., Puazo M., Qu C., Quiroz J., Raj R., Rio Deiros D., RA Santibanez J., Scheel M., Scherer S., Vee V., Wang M., Xin Y., RA Richards S., Reid J.G., Newsham I., Worley K.C., Muzny D.M., Gibbs R.; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [3] RP IDENTIFICATION. RC STRAIN=DH4; RG EnsemblMetazoa; RL Submitted (SEP-2013) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; GB13318-RA; GB13318-PA; GB13318. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 623 AA; 72986 MW; 2967CFCED00CFF97 CRC64; MSDYLSTELA ATCAALGYYD GSKYHLDKHC LDVIKDLIKY LRRDDESHVV RQFLGQTKLL QTDLIKIFVD HSDKLQLWDV LLRLIINITS PVLLIYNEQI PTDKMQRTIY QKLISYTQEY KIALTDDRIW AVLSNRLSEI LKLDNIDRGE EKEMIIERIL IFIRNVLQIP PDENEKRVDN DATIHDEVLF ALNASGVVDL LLFIASNRSE QQYHLQVLEI ISLMLRDQNA NQLAKSGLQR STAEKEKDEA TLLAARLKEK EKKLERVRKY ASARHSHFGG TYVVQNMKAI GENQLICHKP YQKIEALNFA QDKKKMSKPK NKRPMMDPRG ERTSTLSVRL FLKEFCVEFL NAAYNPVMKY ARSCIIGATS TEQTETICYL WTLRFFMEFN RHYKFEVKYV SETISTEIFH LVQRQMEHYY EMIITDKKKI PLWSCRLHVA LRAYQELLYT LIAMDQSTDR GIRESSKVIK SNVFYVPEYR ETILSQLLNF DELKMSRKYL IDLTTTAHVF LKMLSNYCEK NKRSVVVQQV KNRRQRNKKN KKKAESEQKS EQSPPPSVEE RWDEISPQLS IVMREGTIPE VIPFDATLDV PIDEQKVDAM KKIQKLLRQK FLEQAVGLLR ASR // ID H9KTQ8_APIME Unreviewed; 1316 AA. AC H9KTQ8; DT 16-MAY-2012, integrated into UniProtKB/TrEMBL. DT 16-MAY-2012, sequence version 1. DT 09-JUL-2014, entry version 6. DE SubName: Full=Uncharacterized protein; GN Name=LOC727400; OS Apis mellifera (Honeybee). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; OC Apoidea; Apidae; Apis. OX NCBI_TaxID=7460; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=DH4; RA Zhang L., Deng J., Wu Y.-Q., Kovar C., Aqrawi P., Bandaranaike D., RA Blankenburg K., Chen D., Denson S., Dinh H., Firestine M., Gross S., RA Han Y., Hernandez B., Holder M., Jackson L., Javaid M., Jing C., RA Jones J., Joshi V., Kamau G., Korchina V., Lee S., Lorensuhewa L., RA Mata R., Mathew T., Mims S., Ngo R., Nguyen L., Okwuonu G., Ongeri F., RA Osuji N., Pham C., Puazo M., Qu C., Quiroz J., Raj R., Rio Deiros D., RA Santibanez J., Scheel M., Scherer S., Vee V., Wang M., Xin Y., RA Richards S., Reid J.G., Newsham I., Worley K.C., Muzny D.M., Gibbs R.; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=DH4; RG Honey bee genome project; RA Zhang L., Deng J., Wu Y.-Q., Kovar C., Aqrawi P., Bandaranaike D., RA Blankenburg K., Chen D., Denson S., Dinh H., Firestine M., Gross S., RA Han Y., Hernandez B., Holder M., Jackson L., Javaid M., Jing C., RA Jones J., Joshi V., Kamau G., Korchina V., Lee S., Lorensuhewa L., RA Mata R., Mathew T., Mims S., Ngo R., Nguyen L., Okwuonu G., Ongeri F., RA Osuji N., Pham C., Puazo M., Qu C., Quiroz J., Raj R., Rio Deiros D., RA Santibanez J., Scheel M., Scherer S., Vee V., Wang M., Xin Y., RA Richards S., Reid J.G., Newsham I., Worley K.C., Muzny D.M., Gibbs R.; RL Submitted (NOV-2010) to the EMBL/GenBank/DDBJ databases. RN [3] RP IDENTIFICATION. RC STRAIN=DH4; RG EnsemblMetazoa; RL Submitted (SEP-2013) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; GB30213-RA; GB30213-PA; GB30213. DR OMA; CDAYEAG; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1316 AA; 153631 MW; 5B548C508C5DD517 CRC64; MSDYLSTELA ATCAALGYYD GSKYHLDKHC LDVIKDLIKY LRRDDESHVV RQFLGQTKLL QTDLIKIFVD HSDKLQLWDV LLRLIINITS PVLLIYNEQI PTDKMQRTIY QKLISYTQEY KIALTDDRIW AVLSNRLSEI LKLDNIDRGE EKEMIIERIL IFIRNVLQIP PDENEKRVDN DATIHDEVLF ALNASGVVDL LLFIASNRSE QQYHLQVLEI ISLMLRDQNA NQLAKSGLQR STAEKEKDEA TLLAARLKEK EKKLERVRKY ASARHSHFGG TYVVQNMKAI GENQLICHKP YQKIEALNFA QDKKKMSKPK NKRPMMDPRG ERTSTLSVRL FLKEFCVEFL NAAYNPVMKY ARSCIIGATS TEQTETICYL WTLRFFMEFN RHYKFEVKYV SETISTEIFH LVQRQMEHYY EMIITDKKKI PLWSCRLHVA LRAYQELLYT LIAMDQSTDR GIRESSKVIK SNVFYVPEYR ETILSQLLNF DELKMSRKYL IDLTTTAHVF LKMLSNYCEK NKRSVVVQQV KNRRQRNKKN KKSKGAIVEE RWDEISPQLS IVMREGTIPE VIPFDATLDV PIDEQKVDAM KKIQKLLRQK FLEQAVGLLR ASREVWPEND CFGRADITQE EEFLALREIF FADLGVIEEE NVAESRGEQR EENIESLLND EPDDEDDDEE REAEPYSTVV ETDFKFSDFV HRFANVKIVR AMLILLQQFD KNTDEVNHYV NKMLHRITWD CKMPGMMFQA SMFRVFQRIL ESKHRGHKEL QKFAVFIIRR FIEVAQKNRK AYMELLFWKT TRDATEVVEG YNAETDNKKV SRNLWTETQE DELRTLFMEH QTNKYPQDVI DWILENINQE RTRRGIIKKL KEMSLIINSK AVRSEVQKRL PKEWSEEEIA QLTELWEQLK NDDDPVDLIF NGLTIKRPKP KIKEKLLELG LATDRKDLRK KRSRKSNHGK SSWETESVSN SDEDKSSDEE AGKSSSNKNT APNKPRNKGT KKNAKKQTTM VYTDVQLSGL LKDVIERNMS EALEWIKESL LDVLDDRDEE SSEGIPLVPL TDYSSAAMDS PSFQKLIRAM GFTPPADEQE SYWRIPSNML SSMIQKRCNL IDAALAGNFS VEKESQKKNK SDDDEDSESN DDDVLENIKK YFSSRAEPQL STSCEPGIEI SDHPIPLKNF TVLSTSIEHV DTKMEEANEE ENSKKVENPE PERRKSSGRI NLLVDSSDSE LETEIKSVNA EDEEKRRRSD EFEEKNETVK KRRLLDSDEE NESLMSQNTE QKRIKMIISD DEEEQSAPEQ RKKQKSSRII ISDDED // ID I0YPM0_9CHLO Unreviewed; 807 AA. AC I0YPM0; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 16-APR-2014, entry version 6. DE SubName: Full=Uncharacterized protein; GN ORFNames=COCSUDRAFT_58046; OS Coccomyxa subellipsoidea C-169. OC Eukaryota; Viridiplantae; Chlorophyta; Trebouxiophyceae; OC Coccomyxaceae; Coccomyxa. OX NCBI_TaxID=574566; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C-169; RX PubMed=22630137; DOI=10.1186/gb-2012-13-5-r39; RA Blanc G., Agarkova I., Grimwood J., Kuo A., Brueggeman A., Dunigan D., RA Gurnon J., Ladunga I., Lindquist E., Lucas S., Pangilinan J., RA Proschold T., Salamov A., Schmutz J., Weeks D., Yamada T., RA Claverie J.M., Grigoriev I., Van Etten J., Lomsadze A., Borodovsky M.; RT "The genome of the polar eukaryotic microalga coccomyxa subellipsoidea RT reveals traits of cold adaptation."; RL Genome Biol. 13:R39-R39(2012). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AGSI01000016; EIE20339.1; -; Genomic_DNA. DR RefSeq; XP_005644883.1; XM_005644826.1. DR GeneID; 17038315; -. DR KEGG; csl:COCSUDRAFT_58046; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; SQ SEQUENCE 807 AA; 88689 MW; 0C8E853258A65F07 CRC64; MEILESNLLI SVIGGLGRWE SLDNVKVVTF LTMPIDPESD NHALQVEVMH DVKDAFLAQD ALAVVVALVS RPLMRHADGH MSDRDVLIVQ LVVTFLRNLI VIPDSGSSSG SSGSHKSRMS SKLLCRLHED SVLELLLVMA QHTSRADAPL LLEIFAALFN HCDAEVLRKH EPKAATLPKT SLHEVQQPTP TPNQRARLAP TSTEDRQPPR MDSNALLILK GFAEQFLSSS YNLLMGGLRR DLEPGLNISR LSEEDFLRFF KVAGFFTCFV RQQQEEVQKT RQRSGVDGTI GSEESPFAYI SATMGWEMFY LVQSHASLAL LKEMLFTLDI AQRTEAGGFL VQRRTAAARR RKASKQSEAV LEPGSDHEEK AATSDGTDQG QSSPTAAAGD TAAPAATPAT PATPLRQAGH ASSSEHEVSS AAKKGRDKDP LEQLLEEEGE DQQELEHRLK EVACDLRQRV RQELAFPAIV HFYTWLLQGY ATNSRFVNHC LITFLQRIAD PDGLNLEPML YQVSVLRVLH QVLSDAPFRK QPGASEVLSF AARIVRSVIA KLVPGPADED ACRAAADEGE DGQMGCEKAL QKGLAAMMFV ELLFWKNAHD SEEVRDEYHW KATYRKEQSG AGEDAEQSDA SGSDAAAPHA AAPQGQRRKR ARSAIAFSAD DSTLLVDLFE KHGNSKGYVD LIRTDMSDRF KRSQIQRQLK ALGLKKGQLT DRQKGELQRL FHAHKGKRDS LAKIAAELPG QLSKGQIRTQ LRRLGLQLKQ SGAGQEQGGG QRSDSEDSSR GVGNLFSDAS ASHTDSEASS DQVLTND // ID I1BXA7_RHIO9 Unreviewed; 166 AA. AC I1BXA7; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 11-DEC-2013, entry version 5. DE SubName: Full=Uncharacterized protein; GN ORFNames=RO3G_05542; OS Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL OS 43880) (Mucormycosis agent) (Rhizopus arrhizus var. delemar). OC Eukaryota; Fungi; Fungi incertae sedis; OC Early diverging fungal lineages; Mucoromycotina; Mucorales; OC Mucorineae; Rhizopodaceae; Rhizopus. OX NCBI_TaxID=246409; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880; RX PubMed=19578406; DOI=10.1371/journal.pgen.1000549; RA Ma L.-J., Ibrahim A.S., Skory C., Grabherr M.G., Burger G., Butler M., RA Elias M., Idnurm A., Lang B.F., Sone T., Abe A., Calvo S.E., RA Corrochano L.M., Engels R., Fu J., Hansberg W., Kim J.-M., RA Kodira C.D., Koehrsen M.J., Liu B., Miranda-Saavedra D., O'Leary S., RA Ortiz-Castellanos L., Poulter R., Rodriguez-Romero J., RA Ruiz-Herrera J., Shen Y.-Q., Zeng Q., Galagan J., Birren B.W., RA Cuomo C.A., Wickes B.L.; RT "Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals RT a whole-genome duplication."; RL PLoS Genet. 5:E1000549-E1000549(2009). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH476735; EIE80837.1; -; Genomic_DNA. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 166 AA; 18954 MW; 86AF1AD6A107F260 CRC64; MDFEQDQILE ETKSYILGLC SALGAYDDLP SEDGNRHYSV GDEALACLKD LKKAIRVDSE HREKTVLNTI AQFNVIETDI VPLMLSFEGQ STEVANRFIL ACVELLVPMT WPVEKSLNND DEEEQHDPNM IDCYRKYKLG LLQPGVFEVI LSLIEPAVRI PYRYKL // ID I1FDB5_AMPQE Unreviewed; 1352 AA. AC I1FDB5; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 03-SEP-2014, entry version 4. DE SubName: Full=Uncharacterized protein; OS Amphimedon queenslandica (Sponge). OC Eukaryota; Metazoa; Porifera; Demospongiae; Haplosclerida; Niphatidae; OC Amphimedon. OX NCBI_TaxID=400682; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., RA Glavina del Rio T., Bruce D., Barry K., Pitluck S., Srivastava M., RA Simakov O., Chapman J., Mitros T., Hellsten U., Putnam N.H., Fahey B., RA Gauthier M., Larroux C. Richards G.S., Stanke M., Adamska M., RA Darling A., Dacre M., Degnan S.M., Zhai Y., Adamski M., Calcino A., RA Cummins S.F., Goodstein D.M., Harris C., Shu S., Woodcroft B., RA Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.; RT "The genome of the haplosclerid demosponge Amphimedon queenslandica RT and the evolution of animal complexity."; RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG EnsemblMetazoa; RL Submitted (APR-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; PAC:15714073; PAC:15714073; Aqu1.215545. DR OMA; YNARSES; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1352 AA; 155342 MW; 5672E2D7FE61DD80 CRC64; MLQCCTDEYL RGKEAGIRMN LTASLKEELL SGNFEILSQI VIDLENFYRS DFFPDFASRM PLMIHLSSSS RAELINSFSN NLTDGLNSSN TFNYGPYFDS FFNMTGFPSQ CVPGFIALEC AACLQTIPPL CQSVCSHITQ GCYSPFKQGL TDQLSILWNA TRLILDRIES TLPEVYSAQQ NLLPIDFDDD SEFMSFASAA SAECGILLSK NIFGRRRRSL NSFVMLPKSI IGNATLLNGS FSYDGRLPHF CNSNSGGRCW NGNNNQEMDN MRTDFDDSIE NQDLNPVVSF NRTELVEIAQ SLGTPVSNFL ESALTGLDIE VPMGQVRTKK GFVDGADYGL TSLAYVRHLI RALRYDNDLC EVRRRLGNAR VLQEDLIPLL IYFNDDIPLR NDIIRLLVNF TQPVILLFCK SHGHKDPATA KCMIQVSQYL QQYKKDREDH DDDDDIIIDR ILLLFRNILH IPSDPAEEKR TDDDVDAHGQ IIWNLHINGI FELLLFVGSN PNKTQWCIHV LEIVFLLLRE QTPSNLATAD VLVQVAQSFA ERQNDEKLVV WGFSDNSFDI ENRPRHTRIP KNRKFLVTDC QSRPSTYSIR VVLQNICAQV LDYCFNVLMR VVKDTIKRQH SMESVETFYL WAMRFFMEFS RLQNFRVDIV RLHYAVSAYK ELLLHVQEMI QSKDDTVVQS SKVILRDLLY HPEYRDVFLM VLQIYNQAIM PRSFLQDVIE MTHVYLRLVK LCFKQNGQLF IQKKMEQTTA KKKTNSQQPP TEDQLMEMWE SLESEIQHVI TNTAGASELP SPFDGASDTP IEEQKIEVMK NIHKNLKTQN IREAVLMMKA ACEVWPDDIF GSNMVSPSKE ISVLKEIFFN PLSVTTGHEY EEEEERSVQE NVTSIGLEMD LNRFTAAFAN DKIVQVYSLA LANYKSNTDG LNHAIIKMLH TISIKHEMMP MLFQMSLFRI FSDILDEPPL PRYRNAMMFA ELLIWKTCED CYELQEGYGA IQRKSTRTSN NLQQRALRQR PIQEVNSISK KAEMFGLENK RMSYLPYMNN SRMKLEPWSE EEVSTLKSLW QPSDNITLSI EQLSCSFPGR DIRDIKKQLQ NLGLVQPSSR KRKCQENEVI SLETEPREDI KKKKGKKGNV DTLVQAIHAN GYSNQLAWLS TYINDEAKDR ELDSEWEELC IVPVEQSIAE ALETTVFNKL MISIDLMPPS EQEIYWRIPS SMSPQNLQTI AESLNAPQRD TDNLLTSSPE DEEAQDIQNM STNSNTTTYG AVSWSDDEDD NSHLALANDR DPSRSPSEAR KRLPKEREVK QPPPKRIRVR TQFDSNDDDD DDDEVNICRS ISRERDEPHC HKRNARTDHI QP // ID I1FHF8_AMPQE Unreviewed; 90 AA. AC I1FHF8; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 03-SEP-2014, entry version 3. DE SubName: Full=Uncharacterized protein; OS Amphimedon queenslandica (Sponge). OC Eukaryota; Metazoa; Porifera; Demospongiae; Haplosclerida; Niphatidae; OC Amphimedon. OX NCBI_TaxID=400682; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., RA Glavina del Rio T., Bruce D., Barry K., Pitluck S., Srivastava M., RA Simakov O., Chapman J., Mitros T., Hellsten U., Putnam N.H., Fahey B., RA Gauthier M., Larroux C. Richards G.S., Stanke M., Adamska M., RA Darling A., Dacre M., Degnan S.M., Zhai Y., Adamski M., Calcino A., RA Cummins S.F., Goodstein D.M., Harris C., Shu S., Woodcroft B., RA Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.; RT "The genome of the haplosclerid demosponge Amphimedon queenslandica RT and the evolution of animal complexity."; RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG EnsemblMetazoa; RL Submitted (APR-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; PAC:15715531; PAC:15715531; Aqu1.217003. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 90 AA; 9950 MW; F8C977DECE3FD240 CRC64; MSSELVATYS ALGTKDGDQY YKGPECLACV KDLIRALRYD DDLCGVRRHL GKARILQKNP IDLSKLLRVI RPLSNIPADL ALCSTESRVG // ID I1FHG2_AMPQE Unreviewed; 788 AA. AC I1FHG2; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 03-SEP-2014, entry version 4. DE SubName: Full=Uncharacterized protein; OS Amphimedon queenslandica (Sponge). OC Eukaryota; Metazoa; Porifera; Demospongiae; Haplosclerida; Niphatidae; OC Amphimedon. OX NCBI_TaxID=400682; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Lucas S., Shapiro H., Lindquist E., Tice H., Dalin E., RA Glavina del Rio T., Bruce D., Barry K., Pitluck S., Srivastava M., RA Simakov O., Chapman J., Mitros T., Hellsten U., Putnam N.H., Fahey B., RA Gauthier M., Larroux C. Richards G.S., Stanke M., Adamska M., RA Darling A., Dacre M., Degnan S.M., Zhai Y., Adamski M., Calcino A., RA Cummins S.F., Goodstein D.M., Harris C., Shu S., Woodcroft B., RA Leys S.P., Manning G., Degnan B.M., Rokhsar D.S.; RT "The genome of the haplosclerid demosponge Amphimedon queenslandica RT and the evolution of animal complexity."; RL Submitted (MAY-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG EnsemblMetazoa; RL Submitted (APR-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblMetazoa; PAC:15715535; PAC:15715535; Aqu1.217007. DR OMA; TYYLWAM; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 2. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 788 AA; 92208 MW; 11CF1A40F577028C CRC64; MSCCRLLVNF TQPVILSFPE SHTHKDSATT KCMIEVSQYL RQYKEDWEDR DDDDIIIIER ILLLLRNVLH VPSDPAEEKT QWCMHVLEIL FLLLREQSPS NLATAGGARS STERQNDENK IDELMELERV KQKRLQRTFG SRHSKFGGVY IVDNEVTSTG RNRIYHRSLQ GFNDYSFDIE KRPRRTPKPK KRLIIDFQSR PSTYSIRVVL QKFSAQVLDY CFNVLMRVVK DTIKRQHSME NDETYYLWAM RFFMEFSRLH NFRVDIVSHC FSESLQLPTV HQVLQLIASY YEHMCMNKRE RHAAIEWGQR LHYAVSAYKE LLLHVQEMIQ SKDDTVVQSS KVILSNLLYH PEYRDVFVML LRNYNEAVVQ LSFLQDVIEM THVYLRLVKL YSKQNGQLVI QKKRKRTAAK KKTNSQQLPT EDQLMEMWES LESEIQHVIT NTASASELPC PFDGASDIPI EEQKIEVMKN IHEDLKTQNI SEAVLLMKAA REVWPDDVFG SNTVSPSSEI SVLREIFFNP LSVTTSHDYE EEEEEEEEAV QENVTSIELE MDLSRFTAAL ALANYKSNTD ELNHAVIKML HTISIKHEMM PMLFQMSLFR IFSDILDEPP LPRYRVRHRL LELQKFSSRV VADFLILSQQ NKMMFAELLI WKTSGECYEL KEGYGAIQRK KQLKENRNVW TREQEEELSS LYEQFKNETD IVGCILDALP SEQCRTRGII VSKLVSKGLV SSRKDLHKKT KTNKEPWSEE ELFTLKSLWQ PSENINASIE QLLCSFPGLI SPIYDFTN // ID I1HG86_BRADI Unreviewed; 1131 AA. AC I1HG86; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 09-JAN-2013, entry version 3. DE SubName: Full=Uncharacterized protein; GN Name=BRADI2G15960; OS Brachypodium distachyon (Purple false brome) (Trachynia distachya). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; OC Pooideae; Brachypodieae; Brachypodium. OX NCBI_TaxID=15368; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Bd21; RX PubMed=20148030; DOI=10.1038/nature08747; RG International Brachypodium Initiative; RT "Genome sequencing and analysis of the model grass Brachypodium RT distachyon."; RL Nature 463:763-768(2010). RN [2] RP IDENTIFICATION. RC STRAIN=cv. Bd21; RG EnsemblPlants; RL Submitted (NOV-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblPlants; BRADI2G15960.1; BRADI2G15960.1; BRADI2G15960. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1131 AA; 126914 MW; 6FAC5D8274428DA1 CRC64; MDSALLSLTC AGLGASEEDE DGAVVGYVKG DHCLDNLKDL QRFLRRDDQE QREVFKQVCK WKIASRDLVP IIENYQADRN LVITAVKVLV FLTMPVEPSS EDVAQQIEYL WDLKAALTRN VAIAVIVSLL EDPLDHLERT SFTEDDWKLV QLVLTLFRNV LAIQEITLPQ KASGEATQLL CLADSFLELM FQENVMDLIL VLTQHIDEPS GYLKQENLLL LEIFHYLFLG RDPELIARVC SEGLKDGSTS LCKGNPSSAI ASANSLRKIR NVQKGPQKRI AWDNELLYIP KLWITQCFSV LMQSVCDDIV KEHHSIQKSD NTTFFKVVRF VLAFQHEKAS NAQKSNAGPQ LSGTSPSNEH DENLPFCGDI CGPVAATLNE DMFNIVISRW RETYDDLKQT NDYKTLSAAG SLMKNMIGMI YLVLKVLPED SRESQTARVL LYKLFYDQTE QGLTQFLLNL FRSFDTHKQP KSALADLLET IHIMLQLMEK LQSRGTLRVA KRTRKGRKRK TSNDKKENTE SKTENVEESY VDPTDGTKCA SDSLPDLRNE DPVAEPTLLE QGKVDSHGTD LPDVHVDNVV NLESTTQLGG DPSVAGSGEI KRNVIDEEEE SSDSSIDDCP PATSEVDFNV SRLISSLANN SVVQNICWLL KHYKTNSFRT NHYIICMLRR FCEDLQLSPM LYQLSLLTTF YDILAEQKLS SSKEYANIVN FLSKIVRKML RTMKKQPLLF VEILFWKSRK ECHCIGADAL LNELKGDVNN KAAEVGSSKG WRGPINIADS LGDDEADYVI PPEPYDAEDG DSSSGEREGE TQKSMGATNK RNILLSLSGS EEDNDRNIVS RGSQHSRVPK RRGRSIFNEE QEKLIRDLYE KHKDDRKCSH LIAQALDPSG NISSAQISRK LTQLGLRNVV KKTKVPEAPL SAGDLDTQPQ DHFLADAKPE STRHRRKRLH GLSSNPDNAN HGISSDDESL QALKIRTKNK KLPSVELSPG TSQHQDVLQD VDSDDEIIGS MLSRGKKKRS STSDFTVNRQ EHQGSSKNTG PDDRTIGSNA MDAPLHLGLN SFDNNNGHAG ETELLDDFSE PELDHHENTV QRIVDDRDIS EAMDMISPGA SQKSGFKRRH RLVIDSDDDD E // ID I1LDJ2_SOYBN Unreviewed; 1252 AA. AC I1LDJ2; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 2. DT 11-JUN-2014, entry version 10. DE SubName: Full=Uncharacterized protein; OS Glycine max (Soybean) (Glycine hispida). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; OC Phaseoleae; Glycine; Soja. OX NCBI_TaxID=3847; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Williams 82; RX PubMed=20075913; DOI=10.1038/nature08670; RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W., RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., RA May G.D., Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., RA Sandhu D., Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., RA Goodstein D., Barry K., Futrell-Griggs M., Abernathy B., Du J., RA Tian Z., Zhu L., Gill N., Joshi T., Libault M., Sethuraman A., RA Zhang X.-C., Shinozaki K., Nguyen H.T., Wing R.A., Cregan P., RA Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.C., RA Jackson S.A.; RT "Genome sequence of the palaeopolyploid soybean."; RL Nature 463:178-183(2010). RN [2] RP IDENTIFICATION. RC STRAIN=Williams 82; RG EnsemblPlants; RL Submitted (MAY-2013) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR RefSeq; XP_006589510.1; XM_006589447.1. DR EnsemblPlants; GLYMA10G37220.1; GLYMA10G37220.1; GLYMA10G37220. DR GeneID; 100785399; -. DR KEGG; gmx:100785399; -. DR KO; K03155; -. DR OMA; QTREVFK; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1252 AA; 142408 MW; 7E02B1DA1501A966 CRC64; MDTEGLSVIC AGIGTIEADD EGNQIGYIKG QYCLDNLKDL LRFLRRDDPQ TRDVFKQVCK WNIVSKYLIP TIELYHEDRN LLLNAVKVLV FLTMPIEPSS TDISQQLEYL WGLKSALTNS DVAAVIVSFL ERPLENLERN AFSEDDWKLV QLVLTLFRNI LAVQEIPMHQ KSGGLATQLL SLRDRFLELL FRENVMDIIL VISQYVGSSN VYLRQDNLLL LEIFHYILMG QDPELIVWAH LKESKADEQP QTSLYSLQFI LEEEKKRRNI CKLNNLSRHS QFSPTFARLT MDGCKAVIKG NPNSSHNVLL KAQNVARGPT KRTVWDHPRL PSTEDKILEL LHGFVNQFLS GGYNVLMQSI REDIEKEHPS IQKSDVAVFF QVAEFVTSFQ FYKYSASKTK EEGDTFETLS DKDAVTSDFS GQICGPIAAS LNETMFQLII SKWRHAYDGL KETNDYQFLS AAGSLLKNMI RMLDLILKLL PENSKEPQTA RILLYKLFYD QTEEGMTQFL LNLIKTFDIH KQPKSNLSDL VEIIHKVVRL MDNLQSRGAL RVSRKSRKVK KNKIPEGTES GDKLSGDHSC IQNETGISTA NQSAENQPLL EVLPNANSTG EDVVPDDNEH ENRVEEDENS QVGLEPMGAT NSEHVNEDML DGTNNFSEDE QLHAYNEVDF KVSTLVSAFA NHNIIQKLCW LLKFYKSNSL ATNYYIISML RRISDDLELH PMLYQLSLLT TFYDILIEQK SCPCKDYAGI VDFLTCLVRK MLKKMKKQPL LFVELLFWKT RRECHYINAE YLLSELGHLK KESANWNNSQ GDEEIGSSPT KVWTRRSIAD ALGEDEADVV ITHDSRCQQD KLEDVIEGFA STSGSNSGKD VHNGEQLMED ESQLAPRRRK KLVLDGDLER QIKDLYEKFK DEPHCSRHIA EVLDPDGKIS PAQISNMLKR LGLAVAPKRK MGDADAEGHL STSPNQLDGD KRATNHKSVN LEGSLLVQHL QKKKRVQAFN EAQEALIKVL YEQFKDHRRC SYMIANALDE DGKITAAQVS RKLKQLGLSL PQKSSGGKMH PKDADLMDLS NDRINESDDE TLVTLIKRKK MENDKLSRGQ LHGQISEDRL SIDDSDDEML SSVLKEKINS KVSTEQLLEP INVDALSRDD SDDEMPSSAL KRTRRSSLNS KQVELENIQI QERIMGDDSF NEGKTDALER DNRVDSMNSS QIEHQQMDDL ADSEDEVAVS GFPDNARSRR QLRMVIDPED DD // ID I1NGZ9_SOYBN Unreviewed; 1254 AA. AC I1NGZ9; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 09-JAN-2013, sequence version 2. DT 11-JUN-2014, entry version 10. DE SubName: Full=Uncharacterized protein; OS Glycine max (Soybean) (Glycine hispida). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; fabids; Fabales; Fabaceae; Papilionoideae; OC Phaseoleae; Glycine; Soja. OX NCBI_TaxID=3847; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Williams 82; RX PubMed=20075913; DOI=10.1038/nature08670; RA Schmutz J., Cannon S.B., Schlueter J., Ma J., Mitros T., Nelson W., RA Hyten D.L., Song Q., Thelen J.J., Cheng J., Xu D., Hellsten U., RA May G.D., Yu Y., Sakurai T., Umezawa T., Bhattacharyya M.K., RA Sandhu D., Valliyodan B., Lindquist E., Peto M., Grant D., Shu S., RA Goodstein D., Barry K., Futrell-Griggs M., Abernathy B., Du J., RA Tian Z., Zhu L., Gill N., Joshi T., Libault M., Sethuraman A., RA Zhang X.-C., Shinozaki K., Nguyen H.T., Wing R.A., Cregan P., RA Specht J., Grimwood J., Rokhsar D., Stacey G., Shoemaker R.C., RA Jackson S.A.; RT "Genome sequence of the palaeopolyploid soybean."; RL Nature 463:178-183(2010). RN [2] RP IDENTIFICATION. RC STRAIN=Williams 82; RG EnsemblPlants; RL Submitted (MAY-2013) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR RefSeq; XP_006606156.1; XM_006606093.1. DR EnsemblPlants; GLYMA20G30420.1; GLYMA20G30420.1; GLYMA20G30420. DR GeneID; 100796385; -. DR KEGG; gmx:100796385; -. DR KO; K03155; -. DR OMA; HKQPKSD; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1254 AA; 142178 MW; 10C055C344BCD977 CRC64; MDTEGLSVIC AGIGTIEVDD EGNVIGYIKG QYCLDNLKDL LRFLRRDDPQ TRDVFKQVCK WNIVSKYLIP TIELYHEDSN LLLNAVKVLV FLTMPIEPSS TDISQQLEYL WGLKSALTNS DVAAVIVSFL ERPLENLERG TFSEDDWKLV QLVLTLFRNI LAVQEIPTHQ KSGGLATQLL SMRDRFLELL FRENVMDIML VISQCVGSSN VYLRQDNLLL LEIFHYILMG QDPELIVRAH LKESKEDEQP QTSLNSLQFI LEEEKKRRNI CKLNNLSRHS QFSGTFARLT MDGSKAVIKG NPNSSHNVLL KAQNVTRGPT KRTVWDHPRL PSTEDKILEL LHGFVNQFLS GGYNVLMRSI REDIEKEHPS IQKSDVVVFF QVAEFVTSFQ CYKYSASKTT EGGDTFETFS HKDADTSDFS GQICGPIAAS LNESMFQLVI SKWRHAYDGL KETNDYQFLS AAGSLLKNMI RMLDLILKLL PEDSKEPQTA RILLYKLFYD QTEEGMTQFL LNLIKTFDTH KQPKSDLSDL VEIIHKVVKL MDNLQSRGAL RVSRKSRKVK KKIIPEGTES GDKLAGDHSF IQNETGISTV NQSAENQPLQ EGLPNANSTG EDVIPDDNEH ENHVEEVGNS QVGLEPMGAT NSEHVNEDML DGTKDFSEDE QLHAYNEVDF KVSTLVSAFA NHNIIQKLCW LLKFYKSNSL ATNHYIISML RRISDDLELH PMLYQLSLLT TFYDILVEQK SCPCKDYAGI VDFLTCLVRK MLKKMKKQPL LFVELLFWKT RRECHYINAE YLLSELGHLK KESANWNNTQ GDEEIGSSPA KVWTRRSIAD ALGEDEADVV ITHDSGYQKD KLDDVIKGFA PTSGSNSDKD DHNGEQLMED ESQIAPRRRK KLVLDGDLER QIKDLHEKFK DDQHCSHRIA EVLDPDGKIS PAQISNMLKR LGLAVAPRRK MCDADAEGPL STSPNQLDSD KITGATNHKS VNLEGSLLVQ HLQKKKRVQA FNKDQEALIK VLYEQFKDQR RCSYMIANAL DKDGKFTTAQ VSRKLKQLGL SLPLKSSGGK MHPKGADLMD RSNERMDESD DETLVSLVKR KKMESDKLSR GQLHGQTSED KLSKDDSDDE MLSSVLKKKI NSKVSTEQLL EPINVDSSSR DDSDDEMLSS ALKRTRRPSL KSKQVELENI QIHERIMGDD SFNGGITEVS EGEYRVDSMN SSQVEYQQMD DLADLEDEVA VSAVPDNARS RRKLRMVIDP EDDD // ID I1PTB2_ORYGL Unreviewed; 1221 AA. AC I1PTB2; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 19-MAR-2014, entry version 5. DE SubName: Full=Uncharacterized protein; OS Oryza glaberrima (African rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; OC Ehrhartoideae; Oryzeae; Oryza. OX NCBI_TaxID=4538; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RA Wing R.A., Yu Y., Rounsley S., Reddy-Marri P., Goicoechea J.L., RA Sisneros N., Lee S., Song X., Angelova A., Kudrna D.P., de Baynast K., RA Zuccolo A.; RT "The complete genome of Oryza glaberrima."; RL Submitted (JUN-2010) to the EMBL/GenBank/DDBJ databases. RN [2] RP IDENTIFICATION. RG EnsemblPlants; RL Submitted (APR-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EnsemblPlants; ORGLA05G0061000.1; ORGLA05G0061000.1; ORGLA05G0061000. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1221 AA; 136878 MW; 54C1B8105FD3502F CRC64; MDSAALSLTC AGLGGAEEDD DGAVVGYAKG EHCLDNLKDL QRFLRRDDPQ RREVFKQVCK WKIASRDLVP IIENYQADRN LVITAVKVLV FLTMPVEPSS ENVAQQIEYL WDLKAALTRN VAMAVIVSLL EDPLDHLERA SFTEDDWKLV QLVLTLFRNI LAIQEITLGQ KASGEATQLL CLADSFLELM FQENVMDLIL VLTQHMDEPS GYLQQENLLL LEIFHYLFLG RDPELIARAS TAGSKDGSKS LCKGNPNSAS ENSLRKIRNV QRGPQKRIAW DNELLYTPRE GTMEMIRNFL EQFLSGGYNA HFHVKLGITQ CLPVLMQSVC DDIVKEHHSI QKSDITTFFK VARFVLAFQH EKASNAQKSN AAVQLPEASP SDHLDDNLPF LGDICGPVAA TLNEGMFNLV ISRWRETYDS LKETHDYKTL SAAGSLMKNM IDMVYLVLKV LPDDSRESQT ARVLLYKLFY DQTEQGLTQF LLNLFRSFDT HKQPKSDLAD LLGTIHIMLQ LMEKLQARGA LRVAKRTRKG RKKKASKNKI ENTNLNAEKM EQSNADSTDG TKSALESLPD LKNVDSVAEP PLTEQEKVVS NGMDAPDELT GTSVNLDSTS HCEGEPSYAD NGELKGNLID EEDGTSDSSL DDQPPATSEV DFNVSRLIST LANNSVVQNI CWLLKHYKSN SFRTNHYIIC MLRRFCEDLE LAPMLYQLSL LTTFYDILAD QKSSTSKEYT NIVNFLSKIV RKMLRVMKKQ PLLFVDVLFW KTRKECHCID ADALLSDITK DGTNKGGEIG SSKGWRGSIN IADSLGDDEV DLVIPHEPYN ADKDDDSSSG EREDVSKRSM GATNKSNRIL SFSDSEADDN DSSIQIDKIR NTVSRGSQNS EAPKRRGRSI FSEEQEKLMR DLYEKYKDDR KCTHLIAEAL DPSGKITSVQ VSRKLTQLGL RNAMKRRTKV PEAPLSAQEL ATQTDQMLGE HNCNPKPETT RRRRKRLNVS HASYEDNTTD GKSSDEETLQ AIKSRTKNKK VPLVGLSPST SQHQDGLADP DSDDETIGSM LRSGKKKRLL TPDNAMNIEK HQESPDSTNT SNYSPEISQK QEALQDTYSG DEIIDSMHRS GKKKRLLKSG FTANTQEHEE PLINIGQDDE TISSKDNLHH GLNSSNNSGG AGETELLDDF IEPELDNVEN TEQRIIDDIN ITESGDMATS FADQKPGLKR RHKLVIDDDD D // ID I1RRS7_GIBZE Unreviewed; 1162 AA. AC I1RRS7; DT 13-JUN-2012, integrated into UniProtKB/TrEMBL. DT 13-JUN-2012, sequence version 1. DT 14-MAY-2014, entry version 9. DE SubName: Full=Uncharacterized protein; GN Name=FG06814.1; ORFNames=FGSG_06814; OS Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084) OS (Wheat head blight fungus) (Fusarium graminearum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Hypocreomycetidae; Hypocreales; Nectriaceae; OC Fusarium. OX NCBI_TaxID=229533; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084; RX PubMed=17823352; DOI=10.1126/science.1143708; RA Cuomo C.A., Gueldener U., Xu J.-R., Trail F., Turgeon B.G., RA Di Pietro A., Walton J.D., Ma L.-J., Baker S.E., Rep M., Adam G., RA Antoniw J., Baldwin T., Calvo S.E., Chang Y.-L., DeCaprio D., RA Gale L.R., Gnerre S., Goswami R.S., Hammond-Kosack K., Harris L.J., RA Hilburn K., Kennell J.C., Kroken S., Magnuson J.K., Mannhaupt G., RA Mauceli E.W., Mewes H.-W., Mitterbauer R., Muehlbauer G., RA Muensterkoetter M., Nelson D., O'Donnell K., Ouellet T., Qi W., RA Quesneville H., Roncero M.I.G., Seong K.-Y., Tetko I.V., Urban M., RA Waalwijk C., Ward T.J., Yao J., Birren B.W., Kistler H.C.; RT "The Fusarium graminearum genome reveals a link between localized RT polymorphism and pathogen specialization."; RL Science 317:1400-1402(2007). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=PH-1; RG The Broad Institute Genome Sequencing Platform; RA Birren B., Lander E., Galagan J., Nusbaum C., Devon K., Ma L.-J., RA Jaffe D., Butler J., Alvarez P., Gnerre S., Grabherr M., Kleber M., RA Mauceli E., Brockman W., MacCallum I.A., Young S., LaButti K., RA DeCaprio D., Crawford M., Koehrsen M., Engels R., Montgomery P., RA Pearson M., Howarth C., Larson L., White J., O'Leary S., Kodira C., RA Zeng Q., Yandava C., Alvarado L., Kistler C., Xu J.-R., Trail F.; RT "Genome Sequence of Fusarium graminearum (Gibberella zeae)."; RL Submitted (APR-2007) to the EMBL/GenBank/DDBJ databases. RN [3] RP GENOME REANNOTATION. RC STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084; RX PubMed=20237561; DOI=10.1038/nature08850; RA Ma L.J., van der Does H.C., Borkovich K.A., Coleman J.J., RA Daboussi M.J., Di Pietro A., Dufresne M., Freitag M., Grabherr M., RA Henrissat B., Houterman P.M., Kang S., Shim W.B., Woloshuk C., Xie X., RA Xu J.R., Antoniw J., Baker S.E., Bluhm B.H., Breakspear A., RA Brown D.W., Butchko R.A., Chapman S., Coulson R., Coutinho P.M., RA Danchin E.G., Diener A., Gale L.R., Gardiner D.M., Goff S., RA Hammond-Kosack K.E., Hilburn K., Hua-Van A., Jonkers W., Kazan K., RA Kodira C.D., Koehrsen M., Kumar L., Lee Y.H., Li L., Manners J.M., RA Miranda-Saavedra D., Mukherjee M., Park G., Park J., Park S.Y., RA Proctor R.H., Regev A., Ruiz-Roldan M.C., Sain D., Sakthikumar S., RA Sykes S., Schwartz D.C., Turgeon B.G., Wapinski I., Yoder O., RA Young S., Zeng Q., Zhou S., Galagan J., Cuomo C.A., Kistler H.C., RA Rep M.; RT "Comparative genomics reveals mobile pathogenicity chromosomes in RT Fusarium."; RL Nature 464:367-373(2010). RN [4] RP IDENTIFICATION. RC STRAIN=PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084; RG EnsemblFungi; RL Submitted (OCT-2012) to UniProtKB. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS231666; ESU12961.1; -; Genomic_DNA. DR RefSeq; XP_386990.1; XM_386990.1. DR EnsemblFungi; FGSG_06814T0; FGSG_06814P0; FGSG_06814. DR GeneID; 2788472; -. DR KEGG; fgr:FG06814.1; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1162 AA; 132912 MW; 88D99F6006240788 CRC64; MELEDGSTDI VHPEVRAHII SLVSALGGLS VDDGHYELGD DAFEVLRDLK RWIRFYDEKT NRMDVARCIY DGNLVAGDLL PILATWPENA TDSKFKARMA LACFELMVPL TWPMEKDKEQ MTVNHHRHMP VLQMAQVKYK QAIINFDGAR ILHTAIRVAL PSMAVPIGDR TQRDSGIIKL ILFFLRNVAM IELPPGVKNH TDGFLVSRSA TIDAFSYQDI FHVLLTLASN MGDDFRTEDT TVVEIIYHLV KRVDTERLFM NEQQLNKAST GELASMMSKE ESMLKAYNRK GPTRHNRFGT MIWVKREDGK MSSLSGQDAL ADASLRNQKM DSSKTHRPPR RPRKATKDDK DFGLPPKLDS RAYGQLRSFV EDFLDSGFNP LFQHVRKTID REASHVMPYH RRQFFYVVSW FLEAERMRRK ANKQSGKNIS EDVSSFNLIA GVLDQEMFIT LTKALHESIE MKDWNELTAI MRCFTQILLT VHEMSASGNE DDEEIAENVL SRLFYEEATH DAIANIIRNY KDQGFQYLDA ATELVHHFLR ILESYSKQNI DMQVRSRQRT RRKKKAAQDA VGVENDNEEN DGSDNDAESA EKSTKERKFD FARFANRFTP QSVVDTFVAF TKYYRDLSDA QLKRAHRYFY RVAFKSEASI MLFRVDIIHL FYNMIQGQAA LDKSSSMFKE WEELVKQILR KCFKKLEQRP ELLVEMLFSK AGSTAFFLEY GYERQTVSTV NKAKPGAELA FKNTEELDRQ IAIVVGAMLD KNQAGHIAWI KKTLSEAESE RRAFAAAEEA MASIEPPRED PEEDPEQQPV ESGPKLPPTF FVRPDDKDRR TAMFKNSHMR LLMNLVGIKL LGSAADETLE SVWIISSEVS ADVLQDALHY INQAEFSPPT FEEGVLAEHQ LKRKTVPRQK AVFDDDGESS DDGGMFEAGG PTVRKVIDDD NQPKKSPKKR KPRKKLTEEE KKARRKEMRS NKKEKALSYK SSKYVRREDD ETDSEADEAF FAKEREQAKR APVKLLAEGI AAAQKPAKKM PRKRTAAESE SSSEDDSTAS TDDEEEEDED EDDDNNSEND AGIDFIRRAM NGTLVEDEDE EIEQTLPDGS DGESRKRRRI SEEKTQPGED QQMGGMDNNK AGEDEDEDEV PVVSRRPRPQ RRGPFEDDSD DE // ID O62719_BOVIN Unreviewed; 132 AA. AC O62719; DT 01-AUG-1998, integrated into UniProtKB/TrEMBL. DT 01-AUG-1998, sequence version 1. DT 22-JAN-2014, entry version 30. DE SubName: Full=Putative uncharacterized protein; OS Bos taurus (Bovine). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Bovinae; Bos. OX NCBI_TaxID=9913; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Pituitary gland; RA Jung C., Halper J.; RL Submitted (JAN-1998) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF041856; AAC15973.1; -; mRNA. DR UniGene; Bt.22067; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 132 AA; 15024 MW; DFD7D34B1B8746AC CRC64; MFRDQNPEQL AGVGQGRLAQ ERSADFAELE VLRQREMAEK KTRALQRGNR HYRFGGSYIV QGLKSIGERD VIFHKGLHNL RKYSSDLGKH PKKVLKRRQS ARELSISGPL CHQCEVFLRD SALIPGELLQ AA // ID Q01EF3_OSTTA Unreviewed; 614 AA. AC Q01EF3; DT 14-NOV-2006, integrated into UniProtKB/TrEMBL. DT 23-JAN-2007, sequence version 2. DT 14-MAY-2014, entry version 23. DE SubName: Full=Tim circadian rhythm control Timeless protein homolog (IC); GN Name=Tim; OrderedLocusNames=Ot02g04250; OS Ostreococcus tauri. OC Eukaryota; Viridiplantae; Chlorophyta; Mamiellophyceae; Mamiellales; OC Ostreococcus. OX NCBI_TaxID=70448; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=OTTH0595; RX PubMed=16868079; DOI=10.1073/pnas.0604795103; RA Derelle E., Ferraz C., Rombauts S., Rouze P., Worden A.Z., Robbens S., RA Partensky F., Degroeve S., Echeynie S., Cooke R., Saeys Y., Wuyts J., RA Jabbari K., Bowler C., Panaud O., Piegu B., Ball S.G., Ral J.-P., RA Bouget F.-Y., Piganeau G., De Baets B., Picard A., Delseny M., RA Demaille J., Van de Peer Y., Moreau H.; RT "Genome analysis of the smallest free-living eukaryote Ostreococcus RT tauri unveils many unique features."; RL Proc. Natl. Acad. Sci. U.S.A. 103:11647-11652(2006). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CAID01000002; CAL52300.2; -; Genomic_DNA. DR RefSeq; XP_003075028.1; XM_003074980.1. DR STRING; 70448.Q01EF3; -. DR GeneID; 9832581; -. DR KEGG; ota:Ot02g04250; -. DR eggNOG; NOG312012; -. DR HOGENOM; HOG000264570; -. DR OMA; QRTISAD; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome. SQ SEQUENCE 614 AA; 69510 MW; 09938FCBBC4A50B0 CRC64; MSQYSESHLL SLVSTIGARA AGSRYRKDTD CEVSLQDIIR FLQKDNNERR VFLQLTAWNV LAKDLIPLLL SEDDVNVCVL VLKLLVFHTL PPEKDSSSFL EQVRALNLSA RALLDNPVIF PKIMHLVSQA LQTIETRRLV ATDVEAKMLQ LVLTFIRNLL LVSTSSTGFE ATNLDSVDET CKILSECKFL QVLATILQDV RLSPFKAEIP ILVEIFELIL NADKGNSAWY RMRPVSDQHP GHARATRPDR QKFGVSKEQL SRFSAVYVRR SQYVVSEKII RGMRKESSGS RPVRARGGSA LSPTWLSDFS ESLHSAAVNQ FLLIAWEDLK RGRQQMGLSV EYSIRLSCFA RLCSHFVGSS YSKVLNHARN EQRTISADYV ATIANILSTD FVTWIRCEWL ELEQSKLFSE CVPLVELLAC IAQLLTELQN WNQDERIRFA SRPIRYEFLN EDTKYGLICF LRSQLKNFKW SGMPANYLAS LFTLLSEMSN LSSLSSTLSS TYEQVIGETS DQLNDIFMDC TIFMNHLRLT QLFHPKNYAE ASCRARFLNR VDPSTSLRLS ALTSLQLLRM NFHEGIASAS SNLLEKTIQL LNGEAYGNNG AEGSVFVKLL VDHS // ID Q05E95_AEDAE Unreviewed; 1300 AA. AC Q05E95; DT 14-NOV-2006, integrated into UniProtKB/TrEMBL. DT 14-NOV-2006, sequence version 1. DT 03-APR-2013, entry version 15. DE SubName: Full=TIMELESS; OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Aedini; Aedes; Stegomyia. OX NCBI_TaxID=7159; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Rockfeller; RX PubMed=17046601; DOI=10.1016/j.ibmb.2006.08.008; RA Gentile C., Meireles-Filho A.C., Britto C., Lima J.B., Valle D., RA Peixoto A.A.; RT "Cloning and daily expression of the timeless gene in Aedes aegypti RT (Diptera:Culicidae)."; RL Insect Biochem. Mol. Biol. 36:878-884(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY971811; AAY40757.1; -; mRNA. DR eggNOG; NOG257888; -. DR HOGENOM; HOG000008522; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1300 AA; 146182 MW; C34605EE1D8D541F CRC64; MEWLLANPQI NSTFGSLGSF VDDIYLVNDD ALRTLEEIIC KLALEDTSLR TFRRAIGFGQ NVKNDILPLL VNTKDAEIID TTIRLLVNLT VPIECLLPVE LFSKSEIGCH TIFELNKLLV TSKEAFIEWK TTKAVVDHMK TILEKDSKLS IDNCDSINNC LLLLRNILHI PEGNATSGPG PHHQNSNHNT SFQNQIIWNL FTQSVDKLLI HLMSCPQRAY WAVTMAQLIA LMYKDQHIST LQKLLNLWFE STLSESSEDN ESNTSPPQQC SGDSSPMLTS DPTSDSSDNG NYTANIILFG VIDRDFSTGS GKMPSSISKA TDEVDQASRK TAEYPSQIIM ARVIKSHQMY HQSIKVIEGV SCFVKHPSCI KPVTQSEPSS TKQVIDSKQV KPLSVSPDLL DEIHTVRPSL QIQPLQKSPT PVSSSPKSET EISTSEGANK PACSGDNNVF TQPGEDSIPT NSNTKAKLPA STTNGQTQKE KNQISQSETS DCGYGTQVEK ESISTSSNEE DGPNQKPLHQ KPPPNQKQRF NAANKSRNPT TIHEKKELRR KKLVKRSKSN IINMKGLMHH APSDDDISHI LKEFTVDFLL KGYGFLVQEL HAQLLSDLQV QIDTSHFFWL VTYFLKFASQ LELDLEHINT VLSFEIVSYL AYEGVMLCEQ LEQLNREPHN DLLPCLRRIH LVVTAIREFL QALDTYKKSS HLTKEDKDRL KLLQLQICAT EDLRCLFVLL LRCYNPNVQS RQYLQDLIVT NHILLLLLDG VQGIAKANNG DMLVHIKQFA TVEIMHQYGL LLEDFRDNGA FVNDCIFTMM HHVGGDLGQI NVLFQPNILK TYSQIWETEY EICDDWSDLI EYVIHKFINT PQPSPLASTL PEISTQLLSG INPWTQEEKD SLQWYYVQCK QSSCLVADIL NLFQESGNQQ KTRVSIIEQL WEQDIISLMQ YDDLMKVENP GYERNVQTPA FSVASCNSGK RDDENKTPSM AIDDIQVLRD RLLKENKSNM IVWLQKSLLN CCFVKLNVLS GNMYISSSID ENSNVVVMES VSYHCITKKQ SIPVVPWNQE QFSILTYQPF VLLLHKLGFH LPADAKKMFV RIPEFWTADI LYNIALKLGP VEQSIIKFDL NCLQKVLLME KDVKVEPGPM SNSTLDGYTV LARSNKQNPV NSFTSDTNTG WLHVVMRNKN VDTARLVDMP GPSKVIDSAN VVHPSAKAAS SPTVITQSKL THDLSVIVEA SNDDEVPTED DVNADDDDDD DDDDDALEGP CLEEHDVVSA CETASVASDL TRMYVSDEDD KHDIVPSSIL // ID Q0IF87_AEDAE Unreviewed; 1291 AA. AC Q0IF87; DT 03-OCT-2006, integrated into UniProtKB/TrEMBL. DT 03-OCT-2006, sequence version 1. DT 13-NOV-2013, entry version 33. DE SubName: Full=AAEL006411-PA; GN ORFNames=AAEL006411; OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Aedini; Aedes; Stegomyia. OX NCBI_TaxID=7159; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LVPib12; RX PubMed=17510324; DOI=10.1126/science.1138878; RA Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., RA Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., RA Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., RA Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P., RA Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., RA Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., RA Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., RA Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., RA Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., RA Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., RA Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., RA Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., RA Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., RA Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., RA Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., RA Fraser-Liggett C.M., Severson D.W.; RT "Genome sequence of Aedes aegypti, a major arbovirus vector."; RL Science 316:1718-1723(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH477389; EAT41998.1; -; Genomic_DNA. DR RefSeq; XP_001657783.1; XM_001657733.1. DR UniGene; Aae.8928; -. DR STRING; 7159.AAEL006411-PB; -. DR EnsemblMetazoa; AAEL006411-RA; AAEL006411-PA; AAEL006411. DR GeneID; 5567962; -. DR KEGG; aag:AaeL_AAEL006411; -. DR VectorBase; AAEL006411; Aedes aegypti. DR HOGENOM; HOG000008522; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1291 AA; 145162 MW; 52A8A5435C8F7182 CRC64; MEWLLANPQI NSTFGSLGSF VDDIYLVNDD ALRTLEEIIC KLALEDTSLR TFRRAIGFGQ NVKNDILPLL VNTKDAEIID TTIRLLVNLT VPIECLLPVE LFSKSEIGCH TIFELNKLLV TSKEAFIEWK TTKAVVDHMK TILEKDSKLS IDNCDSINNC LLLLRNILHI PEGNATSGPG PHHQNSNHNT SFQNQIIWNL FTQSVDKLLI HLMSCPQRAY WAVTMAQLIA LMYKDQHMST LQKLLNLWFE STLSESSEDN ESNTSPPQQC SGDSSPMLTS DPTSDSSDNG NYTANIILFG VIDRDFSTGS GKMPSSISKA TDEVDQASRK TAEYPSQIIM ARVIKSHQMY HQSIKVIEGV SCFVKHPSCI KPVTQSEPSS TKQVIDSKQV KPLSVSPDLL DEIHTVRPSL QIQPLQKSPT PVSSSPKSET EISTSEGANK PACSGDNNVF TQPGEDSIPT NSNTKAKLPA STTNGQTQKE KNQISQSETS DCGYGTQVEK ESISTSSNEE DGPNQKPLHQ KPPPNQKQRF NAANKSRNPT TIHEKKELRR KKLVKRSKSN IINMKGLMHH APSDDDISHI LKEFTVDFLL KGYGFLVQEL HAQLLSDLQV QIDTSHFFWL VTYFLKFASQ LELDLEHINT VLSFEIVSYL AYEGVMLCEQ LEQLNREPHN DLLPCLRRIH LVVTAIREFL QALDTYKKSS HLTKEDKDRL KLLQLQICAT EDLRCLFVLL LRCYNPNVQS RQYLQDLIVT NHILLLLLDG VQGIAKANNG DMLVHIKQFA TVEIMHQYGL LLEDFRDNGA FVNDCIFTMM HHVGGDLGQI NVLFQPNILK TYSQIWETEY EICDDWSDLI EYVIHKFINT PQPSPLASTL PEISTQLLSG INPWTQEEKD SLQWYYVQCK QSSCLVADIL NLFQESGNQQ KTRVSIIEQL WEQDIISLMQ YDDLMKVENP GYERNVQTPA FSVASCNSGK RDDENKTPSM AIDDIQVLRD RLLKENKSNM IVWLQKSLLN CCFVKLNVLS GNMYISSSID ENSNVVVMES VSYHCITKKQ SIPVVPWNQE QFSILTYQPF VLLLHKLGFH LPADAKKMFV RIPEFWTADI LYNIALKLGP VEQSIIKFDL NCLQKVLLME KDVKVEPGPM SNSTLDGYTV LASFTSDTNT GWLHVVMRNK NVDTARLVDM PGPSKVIDSA NVVHPSAKAA SSPTVITQSK LTHDLSVIVE ASNDDEVPTE DDVNADDDDD DDDDDDALEG PCLEEHDVVS ACETASVASD LTRMYVSDED DKHDIVPSSI L // ID Q0IF88_AEDAE Unreviewed; 1300 AA. AC Q0IF88; DT 03-OCT-2006, integrated into UniProtKB/TrEMBL. DT 03-OCT-2006, sequence version 1. DT 13-NOV-2013, entry version 35. DE SubName: Full=AAEL006411-PB; GN ORFNames=AAEL006411; OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Aedini; Aedes; Stegomyia. OX NCBI_TaxID=7159; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LVPib12; RX PubMed=17510324; DOI=10.1126/science.1138878; RA Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., RA Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., RA Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., RA Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P., RA Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., RA Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., RA Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., RA Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., RA Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., RA Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., RA Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., RA Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., RA Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., RA Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., RA Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., RA Fraser-Liggett C.M., Severson D.W.; RT "Genome sequence of Aedes aegypti, a major arbovirus vector."; RL Science 316:1718-1723(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH477389; EAT41999.1; -; Genomic_DNA. DR RefSeq; XP_001657784.1; XM_001657734.1. DR UniGene; Aae.8928; -. DR EnsemblMetazoa; AAEL006411-RB; AAEL006411-PB; AAEL006411. DR GeneID; 5567962; -. DR KEGG; aag:AaeL_AAEL006411; -. DR VectorBase; AAEL006411; Aedes aegypti. DR KO; K12074; -. DR OMA; LHIPETH; -. DR PhylomeDB; Q0IF88; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1300 AA; 146200 MW; 921351BB19D95468 CRC64; MEWLLANPQI NSTFGSLGSF VDDIYLVNDD ALRTLEEIIC KLALEDTSLR TFRRAIGFGQ NVKNDILPLL VNTKDAEIID TTIRLLVNLT VPIECLLPVE LFSKSEIGCH TIFELNKLLV TSKEAFIEWK TTKAVVDHMK TILEKDSKLS IDNCDSINNC LLLLRNILHI PEGNATSGPG PHHQNSNHNT SFQNQIIWNL FTQSVDKLLI HLMSCPQRAY WAVTMAQLIA LMYKDQHMST LQKLLNLWFE STLSESSEDN ESNTSPPQQC SGDSSPMLTS DPTSDSSDNG NYTANIILFG VIDRDFSTGS GKMPSSISKA TDEVDQASRK TAEYPSQIIM ARVIKSHQMY HQSIKVIEGV SCFVKHPSCI KPVTQSEPSS TKQVIDSKQV KPLSVSPDLL DEIHTVRPSL QIQPLQKSPT PVSSSPKSET EISTSEGANK PACSGDNNVF TQPGEDSIPT NSNTKAKLPA STTNGQTQKE KNQISQSETS DCGYGTQVEK ESISTSSNEE DGPNQKPLHQ KPPPNQKQRF NAANKSRNPT TIHEKKELRR KKLVKRSKSN IINMKGLMHH APSDDDISHI LKEFTVDFLL KGYGFLVQEL HAQLLSDLQV QIDTSHFFWL VTYFLKFASQ LELDLEHINT VLSFEIVSYL AYEGVMLCEQ LEQLNREPHN DLLPCLRRIH LVVTAIREFL QALDTYKKSS HLTKEDKDRL KLLQLQICAT EDLRCLFVLL LRCYNPNVQS RQYLQDLIVT NHILLLLLDG VQGIAKANNG DMLVHIKQFA TVEIMHQYGL LLEDFRDNGA FVNDCIFTMM HHVGGDLGQI NVLFQPNILK TYSQIWETEY EICDDWSDLI EYVIHKFINT PQPSPLASTL PEISTQLLSG INPWTQEEKD SLQWYYVQCK QSSCLVADIL NLFQESGNQQ KTRVSIIEQL WEQDIISLMQ YDDLMKVENP GYERNVQTPA FSVASCNSGK RDDENKTPSM AIDDIQVLRD RLLKENKSNM IVWLQKSLLN CCFVKLNVLS GNMYISSSID ENSNVVVMES VSYHCITKKQ SIPVVPWNQE QFSILTYQPF VLLLHKLGFH LPADAKKMFV RIPEFWTADI LYNIALKLGP VEQSIIKFDL NCLQKVLLME KDVKVEPGPM SNSTLDGYTV LARSNKQNPV NSFTSDTNTG WLHVVMRNKN VDTARLVDMP GPSKVIDSAN VVHPSAKAAS SPTVITQSKL THDLSVIVEA SNDDEVPTED DVNADDDDDD DDDDDALEGP CLEEHDVVSA CETASVASDL TRMYVSDEDD KHDIVPSSIL // ID Q16VM6_AEDAE Unreviewed; 813 AA. AC Q16VM6; DT 25-JUL-2006, integrated into UniProtKB/TrEMBL. DT 25-JUL-2006, sequence version 1. DT 14-MAY-2014, entry version 40. DE SubName: Full=AAEL009518-PA; GN ORFNames=AAEL009518; OS Aedes aegypti (Yellowfever mosquito) (Culex aegypti). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Nematocera; Culicoidea; OC Culicidae; Culicinae; Aedini; Aedes; Stegomyia. OX NCBI_TaxID=7159; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=LVPib12; RX PubMed=17510324; DOI=10.1126/science.1138878; RA Nene V., Wortman J.R., Lawson D., Haas B., Kodira C., Tu Z.J., RA Loftus B., Xi Z., Megy K., Grabherr M., Ren Q., Zdobnov E.M., RA Lobo N.F., Campbell K.S., Brown S.E., Bonaldo M.F., Zhu J., RA Sinkins S.P., Hogenkamp D.G., Amedeo P., Arensburger P., RA Atkinson P.W., Bidwell S., Biedler J., Birney E., Bruggner R.V., RA Costas J., Coy M.R., Crabtree J., Crawford M., Debruyn B., RA Decaprio D., Eiglmeier K., Eisenstadt E., El-Dorry H., Gelbart W.M., RA Gomes S.L., Hammond M., Hannick L.I., Hogan J.R., Holmes M.H., RA Jaffe D., Johnston J.S., Kennedy R.C., Koo H., Kravitz S., RA Kriventseva E.V., Kulp D., Labutti K., Lee E., Li S., Lovin D.D., RA Mao C., Mauceli E., Menck C.F., Miller J.R., Montgomery P., Mori A., RA Nascimento A.L., Naveira H.F., Nusbaum C., O'leary S., Orvis J., RA Pertea M., Quesneville H., Reidenbach K.R., Rogers Y.H., Roth C.W., RA Schneider J.R., Schatz M., Shumway M., Stanke M., Stinson E.O., RA Tubio J.M., Vanzee J.P., Verjovski-Almeida S., Werner D., White O., RA Wyder S., Zeng Q., Zhao Q., Zhao Y., Hill C.A., Raikhel A.S., RA Soares M.B., Knudson D.L., Lee N.H., Galagan J., Salzberg S.L., RA Paulsen I.T., Dimopoulos G., Collins F.H., Birren B., RA Fraser-Liggett C.M., Severson D.W.; RT "Genome sequence of Aedes aegypti, a major arbovirus vector."; RL Science 316:1718-1723(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH477587; EAT38607.1; -; Genomic_DNA. DR RefSeq; XP_001660177.1; XM_001660127.1. DR STRING; 7159.AAEL009518-PA; -. DR EnsemblMetazoa; AAEL009518-RA; AAEL009518-PA; AAEL009518. DR GeneID; 5572105; -. DR KEGG; aag:AaeL_AAEL009518; -. DR VectorBase; AAEL009518; Aedes aegypti. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000122270; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; Q16VM6; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 813 AA; 94456 MW; 9D421ACFA4A003F7 CRC64; MSILLADIDA TCSALGWDDG CKYHMEPDAI MGLKHLIWIL KRDSDDHEYR RYIGQKKVMQ TDLIPMLMSN FDNPDVADVL LRLIVNLTYP TLLLYQGTQP KDAVGRRNYL HLVEILQGYK EAFAVQQAWA ALGDRLQKVL QVDWAERIEE QELIIERILT LTRNVLNVPS NMDMEKRFDN DASLHDQVLW ALHEAGVLDL ILYILGSEHE HQYHLHALEI TCLAYREQSA TSLADASYQR SATEKHRDEL ELLAARKREK AKQLSRIPAA RHSRFGGTYV IQNMKSISDN DLICHQSLQK ALQMEFDTDK KRVKKSFRNV RETGTIERKS AFSVRLFLRE YCIEVLRSSY NNLVRQVRKI LERNAHGQEA SGGHDDSYLL WAIRFFMEFN RASGFKVELV SESLSVPCFH WIITRIEHFV DMMGSDKTRA RLWARRLHVA VQAYREMLHS LQALQKMPDE KAKDLFLMLQ NNIFYVLEYR EVVLHLLINY KETNSTRAYL RDVVETAHMF FKMLEKYCQG TVRVQSKKRA KQKRNKNRQD NAGSRKDPEL NADELEELWL TMAGEVSTCL ANQITLPEED HPIPFDAASD VPIDDQKGDC MIRIHSLLRD GKYEHAIILM RSAREVWPKD DCFGSLASAP EDELMLLKEI FLANLPRNEF IDQNEADDYD DEEEDEEEDN HMTEIDFRFE DFAKRLLNPK VVHACILVLS DWEEISVESL KATVTILHRI AVGSKMPALL FQASLFRIFQ RVFHAPKDAH HEELRRLGVY IVRQFTALAP NNPKIYAELL FYKSIKEANG IEMGYEDIYG NNV // ID Q1A178_BOMMO Unreviewed; 997 AA. AC Q1A178; DT 11-JUL-2006, integrated into UniProtKB/TrEMBL. DT 11-JUL-2006, sequence version 1. DT 19-FEB-2014, entry version 12. DE SubName: Full=Timeless; OS Bombyx mori (Silk moth). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Bombycoidea; Bombycidae; Bombycinae; Bombyx. OX NCBI_TaxID=7091; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=16626732; DOI=10.1016/j.jinsphys.2006.03.001; RA Iwai S., Fukui Y., Fujiwara Y., Takeda M.; RT "Structure and expressions of two circadian clock genes, period and RT timeless in the commercial silkmoth, Bombyx mori."; RL J. Insect Physiol. 52:625-637(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DQ392962; ABD52733.1; -; mRNA. DR RefSeq; NP_001037622.1; NM_001044157.1. DR UniGene; Bmo.2377; -. DR GeneID; 733065; -. DR KEGG; bmor:733065; -. DR KO; K12074; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 997 AA; 113021 MW; EA55762D3D0CBAA6 CRC64; MIQFIALLYK NQHAVTLHKL LNLWLESSLS ESSEDNESNT SPPDRGSDDS SPILTSDPTS DSSDTGGSGK SNDEPNSVNN GWDASSVNNT SENGSQTSQT HNDSESPRKN AENIAEGSMK DENVNEAKSV TFSESNTEAT KDVPAGEDKM KAVISENSDC GYGTQIENQE SVSTSSNDDE LPSEKPVHQK PHNPKQRVNT KSRSGVTVQE RKRKKIVKRG KSNIINVQGL SHKTPTDDDI SNILKEFTVD FLLKGYNVLV QTLHSQILTN LQLEIETSHF FWLVTYFLKF ATQIELDLEH LCSVLSFDIV SYLTAEGVNL CEQFELAVKL DGNGLKPCMR GLHLVVTAIR ELVQAIEVYK KISFIRKDDR EALIKLQIKM CETDELRSLM VLLLRTYNPK YHTKQYLQDI IVTNHILLLF LDNVMKMTEY NGTTNMVDHI KQFATPEIMY QYGLLLEDYA SNGEFVNDCI FTVMHHAGGE LESLITLFQP KILKTFTSIW KSEFEICDDW SDLIEYVINT FIKKPHTLQT MADIRLDTEN FDDEIVSKPV TTPEDVAGPR TDDIAKKNNI ISNASNASVE TWTGDELSSL NWNYMQCNSL SDVIGEIVKL FEDYGTFKSR QSIITQLYKQ NIIDKDKFET FLNAEKQWNT RTVELNKETR DDEIGKLCEQ LANDGKSNFL DWVQKVLLDT CCAKIYIQKK SATKFLADQA DCKLLNFELF KKKSDFPSLS PVSCHSLLFN QSVPLVPWNC RQASICKDLK FLQLLHMLGF HMPVDSGKVF IRIPHFWTAD FLFEVAGKIA PIDKKTLKFN IDDLQNSMTH EKYRNLIVLT TNYTKDITMV ETSDNIYQVH KQKHLATMVN FTPMPGTSFG TQRDDERRNW LEVVKKSQEY KITLNLGRLV GEEGDIQPDV VMKLPSSEPS ESLPAPPISG NITDTEYYNN SVCETASVAS DLTRMYVSDE DEKPEVVLRP VHEVNNLAES SDSGNLKRPR VQFAPNF // ID Q23DS8_TETTS Unreviewed; 1252 AA. AC Q23DS8; DT 18-APR-2006, integrated into UniProtKB/TrEMBL. DT 16-APR-2014, sequence version 2. DT 03-SEP-2014, entry version 31. DE SubName: Full=Yip1 domain protein; GN ORFNames=TTHERM_00046130; OS Tetrahymena thermophila (strain SB210). OC Eukaryota; Alveolata; Ciliophora; Intramacronucleata; OC Oligohymenophorea; Hymenostomatida; Tetrahymenina; Tetrahymenidae; OC Tetrahymena. OX NCBI_TaxID=312017; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SB210; RX PubMed=16933976; DOI=10.1371/journal.pbio.0040286; RA Eisen J.A., Coyne R.S., Wu M., Wu D., Thiagarajan M., Wortman J.R., RA Badger J.H., Ren Q., Amedeo P., Jones K.M., Tallon L.J., Delcher A.L., RA Salzberg S.L., Silva J.C., Haas B.J., Majoros W.H., Farzad M., RA Carlton J.M., Smith R.K. Jr., Garg J., Pearlman R.E., Karrer K.M., RA Sun L., Manning G., Elde N.C., Turkewitz A.P., Asai D.J., Wilkes D.E., RA Wang Y., Cai H., Collins K., Stewart B.A., Lee S.R., Wilamowska K., RA Weinberg Z., Ruzzo W.L., Wloga D., Gaertig J., Frankel J., Tsao C.-C., RA Gorovsky M.A., Keeling P.J., Waller R.F., Patron N.J., Cherry J.M., RA Stover N.A., Krieger C.J., del Toro C., Ryder H.F., Williamson S.C., RA Barbeau R.A., Hamilton E.P., Orias E.; RT "Macronuclear genome sequence of the ciliate Tetrahymena thermophila, RT a model eukaryote."; RL PLoS Biol. 4:1620-1642(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG662712; EAR94710.2; -; Genomic_DNA. DR UniGene; Tth.28188; -. DR STRING; 5911.XP_001014608; -. DR EnsemblProtists; EAR94710; EAR94710; TTHERM_00046130. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1252 AA; 147866 MW; 76EEF97C99689FF5 CRC64; MEDLEGEHLR RDLNEQDDLD NLDLQYDRNN EYLDIEKFNS DLLFAVQGLG SVKQVNEIEI YVKGPHCEES IKDLIRLCRK DDSDEPLARK KLAVWKTFEN DLIQLLLTQY QDKKLAFYLI LLMVNLTEQP TKTCVIKNEL RDALYEYKLS FLKPQVIGTL MQHLGDCIEN HQMMLLRKQT TREKGKNETK AHEQMIELIV ILIKNILAIR DSPYNDSNHN EIYRNMHFHL LCQMKREHCF DLLIFLSQDF SKFDVLKKLD VIFLEIFYHI FSGFDPEWLC SANGNGSSDF AKLLEKDRLE KKKLNQMIPS RHTRFQANFR FKRMLDDTKK LTTNPFAGDQ FDQTKVTKNQ LNKPIPRKFL QQQEGIFRKR LHLDLKVDMP LQHNLTQNLT IDQQDDEDTI KSELVTFKSV MLQFSLEFIK YSFCPLFEQC YNLLYTDSEK LEPIDTVYYF VLMGFGLKLT RIVVFEHKAS ELEIVDIAVA LQLTQFQLIF SKLVKEVTHN KKRSFNLKNF YSTVYVFNEL LQVIRVMSTD NSQMNRKNSQ IMLQNIFHHD ITKALRIGVD YCQYNVLNNE VLKNLVELIN IFFDLLESYS KGKVLTLQTD KLVKKKKKKV NSKSKKALER QLQSEMNDFI EKDPNEGQED DEDFNPNKEL EIQNVEKKED AYDEDDDEDS DDDGPQFQER KYNLQSEFAI LADYNVILKV LQLIQGDKIL TNSPNLNNAV YKFIQRITDL LKADWILYQV DFISIIQEIC SNQEIKMRLD CKKFIELFRK IIRNMFEKIK QNKLLLVEML FRFTDATLKN SILCNYEDLE KNENEFDNIL NENEAENADQ QTILERKVWI EQEDRAIINN YETFKDLTNV FEQLGLVLNG LGFYDKTPLD IRRRVKYLKL HKGKQRAEKI FKEIYASKKV SIKRAVRELY LKLKDNEENV NNIEINDIQI LLDSIFVNFK EYIYFIEEQN TNLTDFERLV QVQDYCIVPY TVKDFDILNL QSAQQLLESL GFRAPAQGQI YWRVPGFFKV SDVDLLKEKV DKFLQNPEIL LENNQEEGLE GQDQLSSKKK KSKQKKIKNQ GQMQEEESAN KQIENEESQE NKEIQNVEED DQDVAFIRDY EEGEQNEAQQ ESNNILNQND QEQSQNNNKS TSKKRKLCKV KQNDIKSDDS EMIYMGYDEQ SNNENSQQNQ NLIQSRKSSF DASKSFMNAE KENSNSFVRQ FLNESNNENN KQMDENSMSA NSMIFNKYQN KKINNFNSDD QI // ID Q299R9_DROPS Unreviewed; 1395 AA. AC Q299R9; DT 04-APR-2006, integrated into UniProtKB/TrEMBL. DT 14-OCT-2008, sequence version 2. DT 03-SEP-2014, entry version 39. DE SubName: Full=GA20636; GN Name=Dpse\GA20636; ORFNames=Dpse_GA20636, GA20636; OS Drosophila pseudoobscura pseudoobscura (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=46245; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25 / Tucson 14011-0121.94; RX PubMed=15632085; DOI=10.1101/gr.3059305; RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., RA Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., RA van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E., RA Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., RA Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., RA Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., RA Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., RA Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., RA Weinstock G.M., Gibbs R.A.; RT "Comparative genome sequencing of Drosophila pseudoobscura: RT chromosomal, gene, and cis-element evolution."; RL Genome Res. 15:1-18(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM000070; EAL27632.2; -; Genomic_DNA. DR RefSeq; XP_001358493.2; XM_001358456.2. DR EnsemblMetazoa; FBtr0283798; FBpp0282236; FBgn0080630. DR GeneID; 4801392; -. DR KEGG; dpo:Dpse_GA20636; -. DR FlyBase; FBgn0080630; Dpse\GA20636. DR InParanoid; Q299R9; -. DR KO; K03155; -. DR OrthoDB; EOG7WDN1T; -. DR GO; GO:0003682; F:chromatin binding; IEA:InterPro. DR InterPro; IPR001005; SANT/Myb. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SMART; SM00717; SANT; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1395 AA; 160163 MW; 9CAE6211CCF7D216 CRC64; MSVLLADIDA TCAALGYSDG QRYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRAKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGPP SDNHGRKVFM ELIDILQGYK AAFAKDKIWT ALFDKLKQAL EIGFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLYREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPTG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI KEEAQVTRRS AFTVRLCLRE YCTEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNARA LFDMLLNNVC YVLEYRETIL HLLMNYNEAH STKVFLRDVV ETANVFIKMM ERFCQDSVVV QDKRRGAGGR RKKQPKAKSK QTAAPQPTED ELSSKWAEMA SEVCTVLFGE LVLPEDERPI PFDAASDKSI DDQREDCMIR INKLLRTEKL EQAIALLRAA REVWPENEVF GAVAAAPKDE LLLLREIFMH NITTGESRKV KRRTRRTRDE ENDDDDDAEN EEFEEQNKGL TEKTFKFDDF ARRLLHPKIV RACTLVLTDW AQIPTRALKA AVTVLHRIAY GCSCPGMLFQ AKLFRIFQQV LSVERDAHQE ELRRLGIYVV RKFVEVAPTN PKIYAELLFY KGIREANELE TGYCDAYESG TKGTWSEEQE TELRFLFEEN QRNPETDKDV IDWILDNLAD KTRTRRGVLK KMKEMGLLFK APTKRSTKSA QSGKNLWQPE EDEMLRSLYD QYRTEPDCLE RLVREFGEQR SKQQIIKRML QIHLIADKSE ILPAKSSKGR GKGKSKRQQE ANSDSGSGSG SEADEYMEEP MFENAGARKP QNKSRSRQVV RTPLDVGTVQ ALIAQVDTEK YQPAFEWLTE CLNDASDDTD EPAEDDDGVP LLPLQQSQKD AMEDGNFQKV LVALGMQPPI AGMENYWRVP TYLNAADLKL RAKIVSGEEV EIEPENIREE DVDEEDDEED YLDKRSRQRQ QAQAENIAAQ QQSRLDSLMF SKSDDDDQAE QRAALKRKGN GKQAKRQRKG KAKAMETKES DDEEEKEKET EQPSRASTDD LFEQLKAKRA TKIKLGDMVL NESTKAVGDE DGDGDGDDDA FNFNSEDYRA RLLELEDEDE ENEAEEQNKE NNTTKSSSLS LQRARRVNVI DSDSDNDDAG GASPADKTNK RPRSDDGQES DEAAEESDDD ANFLARKKPA KVDIGRGEPA KRRRVAIIDD DDDEF // ID Q29MC5_DROPS Unreviewed; 1238 AA. AC Q29MC5; DT 04-APR-2006, integrated into UniProtKB/TrEMBL. DT 14-OCT-2008, sequence version 2. DT 03-SEP-2014, entry version 35. DE SubName: Full=GA16835; GN Name=Dpse\GA16835; ORFNames=Dpse_GA16835, GA16835; OS Drosophila pseudoobscura pseudoobscura (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=46245; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25 / Tucson 14011-0121.94; RX PubMed=15632085; DOI=10.1101/gr.3059305; RA Richards S., Liu Y., Bettencourt B.R., Hradecky P., Letovsky S., RA Nielsen R., Thornton K., Hubisz M.J., Chen R., Meisel R.P., RA Couronne O., Hua S., Smith M.A., Zhang P., Liu J., Bussemaker H.J., RA van Batenburg M.F., Howells S.L., Scherer S.E., Sodergren E., RA Matthews B.B., Crosby M.A., Schroeder A.J., Ortiz-Barrientos D., RA Rives C.M., Metzker M.L., Muzny D.M., Scott G., Steffen D., RA Wheeler D.A., Worley K.C., Havlak P., Durbin K.J., Egan A., Gill R., RA Hume J., Morgan M.B., Miner G., Hamilton C., Huang Y., Waldron L., RA Verduzco D., Clerc-Blankenburg K.P., Dubchak I., Noor M.A.F., RA Anderson W., White K.P., Clark A.G., Schaeffer S.W., Gelbart W.M., RA Weinstock G.M., Gibbs R.A.; RT "Comparative genome sequencing of Drosophila pseudoobscura: RT chromosomal, gene, and cis-element evolution."; RL Genome Res. 15:1-18(2005). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=MV2-25; RX PubMed=17994087; DOI=10.1038/nature06341; RG Drosophila 12 genomes consortium; RT "Evolution of genes and genomes on the Drosophila phylogeny."; RL Nature 450:203-218(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH379060; EAL33769.2; -; Genomic_DNA. DR RefSeq; XP_001356704.2; XM_001356668.2. DR STRING; 7237.FBpp0280599; -. DR EnsemblMetazoa; FBtr0282161; FBpp0280599; FBgn0076849. DR GeneID; 4816795; -. DR KEGG; dpo:Dpse_GA16835; -. DR FlyBase; FBgn0076849; Dpse\GA16835. DR InParanoid; Q29MC5; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1238 AA; 140074 MW; 1A2E794B5C7525AC CRC64; MDWLLTAPQL HSAFASLGSL EGDTYVVSPN ALSILEEINH KLTYEDQTLR TFRRAICFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAK STKSVVEYMK HILESDPKLS PQKCDQINNC LLLLRNILHI PETHGICVMP MMQSNNLHGI TMQNTILWNL FIQSIDKLLI YLMTCPQRSF WGVTMVQLIA LIYKDQHVST LQKLLDLWFE ASLSESSEDN ESNTTPPKQG SGESSPMLTS DPTGSDSSDN GSQGRGMSIS MSLNMSMSMS MNVSMSSLCG KKETPEERQL ALWEGTEATL QEVSRKGQEY QDAIDAKERM GSAGMDDDED YEDSDFIHLQ LHQAMQAEEE DEECDNEVAA ASSEPLNLKT QPADNVNDTT TTTSLSSSIM PFRSPLPVGS RPSYSHAPPQ HQSYAAYVAA IKLSQKSPHA GKLQLTKGKC CPQKRECSST QSELSDCGYA TQVENQESVS TSSNDDDMPQ GKPLHQKPPC NTKLRNKQRP ILPPLDKKEL RRKKLVKRSK SSLINMKGLV QHIPTDDDIA NLLKEFTVDF LLKGYNYLVE DLHAQLLTNT LPIDTSHFFW LVTYFLKFAA QLELDMEHID TILTYDVLSY LTYEGVMQCE QLEQCARQRD SDLKPHLRRM HLLVTAIREF LQAIEAYNKV SHLSDDDRDH LRQLHIQIAD TSDLHCLFVL LLRRFNPTIY SKQYLQDLIV TNHILLLILD NRPQLDGKKT ENLTQHVAQF ATLEVMHYYG ILLEDFTSNG EFVNDCIFTM MHHVGGDLEQ IGVLFQPIIL KTYSRIWEME FTLCDDWSDL IEYVINKFMN TPPKTPMTIP TTSLTAMTKE HNLEHAKCSW NADEMDTLYW YFVQSRSTND VVGKIVRLFS NNGNKEKSRI SIIQQLLQQD IITLLEYDDL MRYEDAEYQR TLLNTPTSVT TESGIEMKDG GFGRPSGDIQ ILLDLIIKDQ KGQHLEWVQK VLLECCYIKL NLKSGRQMPH IMEPVAYHYI LLHKSIPVVQ WNNEQSAAMM YQPFVLLLHK LGIQLPVDAG SIFARIPDYW SAAQMYGMAK KLGPVNKQAL KFDATELEEA AAAAAASAAA SAASMRSHHN RGPRNSLSSQ SSLEVDMGDT DGELPLIPEV DAAVEKAHAM DCSSSSNNEF FAVPKVKTAN TMMRYTPDTT PPVPNWLQLV MRSKRNPRPA PIGEINDW // ID Q3LGB9_XENLA Unreviewed; 1286 AA. AC Q3LGB9; DT 08-NOV-2005, integrated into UniProtKB/TrEMBL. DT 08-NOV-2005, sequence version 1. DT 11-JUL-2012, entry version 25. DE SubName: Full=XTimeless1; GN Name=XTim1; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; OC Xenopus. OX NCBI_TaxID=8355; RN [1] RP NUCLEOTIDE SEQUENCE. RA Tsujimura T., Hashimoto H., Takisawa H.; RT "Xenopus Tim1 and Tipin are required for stable association of RT Claspin/Mrc1 with replication forks."; RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB208776; BAE45344.1; -; Genomic_DNA. DR ProteinModelPortal; Q3LGB9; -. DR DIP; DIP-46440N; -. DR HOVERGEN; HBG079258; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; SQ SEQUENCE 1286 AA; 149406 MW; 4CB215A7B1B04814 CRC64; MDLYMMNCEL LATCSALGFL EGDTYHKEPD CLESIKDLIR YLRHEDDTRD IRQQLGAAQI LQNDLVPLVI QHHNDKQLFD AVIRLMVNLT QPALLCFGKV PQDPTFRHHF LQIVSYLQAY KEAFADERLF GVLSEKLYDL LQMEWEQREE EHNLLIERIL LLVRNILHVP PDPEEEKSVD DDASIHDRVL WAIHMSGMDD LIKFLASSET EQQWSMHVLE TVSLMFRDQI AEHLAATGQA RSTAERDTDI KNLEILRQRE MAEKKNRALQ RGNRHSRFGG SYIVQGLKSI GDKDVIYHKG LQNFKNYTHD LGKEMRRVPK RKQQAKDTEA RRRSALNVRL FLKEFCIDFL ENCYNRLMYI VKDNLIREKA QQHDETYYLW SMAFFMGFNR LFHFKPELVS ETVSIRTFHF IEQNLTNYYE MMLTDKKEAT SWARRMHLAL KAYQELLSNV HEMDHSKEEA VRESSKIIKN NIFYLMEYRE LFLALFRKFD ETKQPRSFLK DLVETTHLFL KMLEKFCKGK QTVVVQNRRV NERKKKSSVS GTKAAQPKSI EELEAIWTNV SEQLRTCTLD SANLPDSVVP FDAASEIPVE EQRAEALVRI QDGLFSGHAS EALVLLRSAR EVWPEGDVFG AAEIEPEEET ELLKQILFAD LPRSTQAEIE DLGEEEEEEE IEEEELTSVQ VSEKEFNVLD YMKRFANSNV VKTYVLLLKN YQQNSAHTNH CVAKMLHRIA YDLKMEALLF QLSVFCTFNK ILVDPAASAY KELVVFSKYI LNKFFSLAAT NNKAYVELLF WKNTNVIREM TEGYRKLGEE ESEGNRKRIK WTPEDDEELR SLYLQLKEVE DVDVVDNILA NLKPGTRTRK QVINHLVQMG LADSVKDFKN EVKGTRIVLW TEDQELELQS LYEEFKDTDD ILGNIMKNVT AKRSKARIIE KLISMGLVFD RKELYKKRRK MGKSSGMSEE EFLHELEFDG KHSVEDVEED EEEEEESEEE EEQREDLKYK QNAKVQTGGK MEPFTDKKIQ HLVHTLQQEG LSGPLLWLQN CLNRTAEDKE EDGSSQAIPL VPLTEDNEDA MENKTFQKLL KKLGIRAPAN EQESFWRIPG KLSPEQLRKA ASCLVPLAAE VAHDVLASSE EQETNVEQRA EALRALLLAR KKKSTVQQEL QEEKSPEKSL ESHTQKRRPK TAKKRSVMVD SDEENSIENT NEHKESEQLP PDANTETETK LNRPNKSKKR SRIVDSDDDD DGSMTEEQGK EPLELDQKGS LSESDTEENV QPTKKKRLII EDEDED // ID Q3U574_MOUSE Unreviewed; 1196 AA. AC Q3U574; DT 11-OCT-2005, integrated into UniProtKB/TrEMBL. DT 11-OCT-2005, sequence version 1. DT 09-JUL-2014, entry version 72. DE SubName: Full=Putative uncharacterized protein; GN Name=Timeless; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX PubMed=10349636; DOI=10.1016/S0076-6879(99)03004-9; RA Carninci P., Hayashizaki Y.; RT "High-efficiency full-length cDNA cloning."; RL Methods Enzymol. 303:19-44(1999). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX PubMed=11042159; DOI=10.1101/gr.145100; RA Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., RA Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.; RT "Normalization and subtraction of cap-trapper-selected cDNAs to RT prepare full-length cDNA libraries for rapid discovery of new genes."; RL Genome Res. 10:1617-1630(2000). RN [3] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX PubMed=11076861; DOI=10.1101/gr.152600; RA Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., RA Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., RA Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A., RA Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., RA Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., RA Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., RA Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.; RT "RIKEN integrated sequence analysis (RISA) system--384-format RT sequencing pipeline with 384 multicapillary sequencer."; RL Genome Res. 10:1757-1771(2000). RN [4] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium; RT "Functional annotation of a full-length mouse cDNA collection."; RL Nature 409:685-690(2001). RN [5] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team; RT "Analysis of the mouse transcriptome based on functional annotation of RT 60,770 full-length cDNAs."; RL Nature 420:563-573(2002). RN [6] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RA Arakawa T., Carninci P., Fukuda S., Hashizume W., Hayashida K., RA Hori F., Iida J., Imamura K., Imotani K., Itoh M., Kanagawa S., RA Kawai J., Kojima M., Konno H., Murata M., Nakamura M., Ninomiya N., RA Nishiyori H., Nomura K., Ohno M., Sakazume N., Sano H., Sasaki D., RA Shibata K., Shiraki T., Tagami M., Tagami Y., Waki K., Watahiki A., RA Muramatsu M., Hayashizaki Y.; RL Submitted (MAR-2004) to the EMBL/GenBank/DDBJ databases. RN [7] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RG The FANTOM Consortium; RG Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group); RT "The Transcriptional Landscape of the Mammalian Genome."; RL Science 309:1559-1563(2005). RN [8] RP NUCLEOTIDE SEQUENCE. RC STRAIN=C57BL/6J; TISSUE=Thymus; RX PubMed=16141073; DOI=10.1126/science.1112009; RG RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium; RT "Antisense Transcription in the Mammalian Transcriptome."; RL Science 309:1564-1566(2005). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AK153838; BAE32206.1; -; mRNA. DR RefSeq; NP_001157552.1; NM_001164080.1. DR UniGene; Mm.6458; -. DR PRIDE; Q3U574; -. DR GeneID; 21853; -. DR KEGG; mmu:21853; -. DR UCSC; uc007hlu.2; mouse. DR CTD; 8914; -. DR MGI; MGI:1321393; Timeless. DR HOGENOM; HOG000133002; -. DR HOVERGEN; HBG079258; -. DR KO; K03155; -. DR NextBio; 301334; -. DR ArrayExpress; Q3U574; -. DR Bgee; Q3U574; -. DR Genevestigator; Q3U574; -. DR GO; GO:0005634; C:nucleus; IDA:MGI. DR GO; GO:0042803; F:protein homodimerization activity; IDA:MGI. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:MGI. DR GO; GO:0030324; P:lung development; IMP:MGI. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1196 AA; 137432 MW; ED8B120D87B20E44 CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDSSVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKSID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQT PEQLAGVGQG RLAQERSTDV AELEVLRQRE MAEKRARALQ RGNRHSRFGG SYIVQGLKSI GEKDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLRERA QQHDETYYMW AMAFFMAFNR AATFRPGLVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDEA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLR DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKKKKKVQD QGVAFSQSPG ELEAMWPALA EQLLQCAQDP ELSVDPVVPF DAASEVPVEE QRVEAMVRIQ DCLTAGQAPQ ALALLRSARE VWPEGNAFGS PVISPGEEMQ LLKQILSTPL PRQQEPEEGD AEEEEEEEEE EELQVVQVSE KEFNFLEYLK RFASSTIVRA YVLLLRSYRQ NSAHTNHCIA KMLHRLAHGL GMEALLFQLS LFCLFNRLLS DPAAAAYKEL VTFAKYIIGK FFALAAVNQK AFVELLFWKN TAVVREMTQG YGSLDSGSSS HRAPLWSPEE EAQLQELYLA HKDVEGQDVV ETILAHLKVV PRTRKQVIHH LVRMGLADSV KEFQKRKGTQ IVLWTEDQEL ELQRLFEEFR DSDDVLGQIM KNITAKRSRA RVVDKLLALG LVSERRQLYK KRRKKLAPSC MQNGEKSPRD PWQEDPEEED EHLPEDESED EESEEGLPSG QGQGSSSLSA ENLGESLRQE GLSAPLLWLQ SSLIRAANDR EEDGCSQAIP LVPLTEENEE AMENEQFQHL LRKLGIRPPS SGQETFWRIP AKLSSTQLRR VAASLSQQEN EEEREEEPEP GVPGEQGPSE EHRTEALRAL LSARKRKAGL GPTEEEATGE EEWNSAPKKR QLLDSDEEED DEGRRQVSGT PRVHRKKRFQ IEDEDD // ID Q3ZTQ6_DANPL Unreviewed; 1210 AA. AC Q3ZTQ6; DT 27-SEP-2005, integrated into UniProtKB/TrEMBL. DT 27-SEP-2005, sequence version 1. DT 03-OCT-2012, entry version 9. DE SubName: Full=Timeless; DE Flags: Fragment; OS Danaus plexippus (Monarch butterfly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Papilionoidea; Nymphalidae; Danainae; Danaini; Danaina; Danaus; OC Danaus. OX NCBI_TaxID=13037; RN [1] RP NUCLEOTIDE SEQUENCE. RA Froy O., Reppert S.M.; RT "Monarch butterfly timeless."; RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY367059; AAR15505.1; -; mRNA. DR DIP; DIP-29601N; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 1210 1210 SQ SEQUENCE 1210 AA; 137365 MW; F072053937E6DF8F CRC64; MEWVHRSPQI HSTFSNLGFT NGDGYHINEN YNAVLESILQ NILTEDKQLR SYRRSINFGQ NIKKDLIPLL INTKDDKTIV LVIKILVNLT IPVECLLSLD SVGRTDVGRH TIFEINNLLT STKAAITDHR VTKVVIDFLK KNAEIDQSSK LSSDECTNIS NGLLLLRNIL HIPEEINNPS YNPRTVQNQI LWNLFSQSID KVLIKLMNIT DAINWGVTMV QIIALLYKDQ HVTTLQKLLN LWLEASLSES SEDNESNTSP PNRGSDDSSP MLTSDPTSDS SDAGASGKSN GEQNSVNNSW DSSSRNNSDN GKPSFDSQKE NELANDSSES NENNMYIGNS KDNLEESSSN DNNHISNDHS NSHNMKNNEK KTIISEPSDC GYGTQIENRE SISTSSNEDE LPTTKPVHQK PHNTKQRTNN KVRAGVTLQD RKRKKIVKRG KANIINVQGL LHNTPTDDDI SNVLKEFTVD FLLKGYNSLV RTLHTQILTN VQLEIDTSHF FWLVTYFLKF ATQIELDLEH VCSVLSYEII LYLTAEGVNL CEQFELAIKL DGSDLKPSIR RLHLVVTAIR EFVQAIEVYK KSAHLSSNDQ EKLLKLQMKM AQTEELRSLL VLLLRHYHPK YHSKQYLQDL IVTNHILLMF LDSVMKLPQY EGPNTMVDHI KQFASPEIMH QYGLLLEDYE GNGGFVNDCI STLMHHVGGE LGSLISLFQP KILKTFTSIW KSEFEICDDW SDLIEYVINT FIKKPYKLQN YSNIQLEMEI FDDDMKPKEN LIDPEPAPEI ISVMKKVNEN ENITDGWNEE EISSLNWNYM QCNTAVDVVE EILRMLKEDG IVKTRESIIK ELYRQLIINK EEFEGLSKVD SDKNSKAIRD KRENEIGKLC EQLRQDGKSL FLDWVQAVLL ETCFAKIHVN KIEVDRVRQS SYTTQDAHRH VFDTMLKRNT DMPVISPVSY HSLLLNQSVP LVPWNNEQAA VCKDLKFLQL AHKLGFHMPV DTGKVLIRIP NFWTPDFLYE VAEKISPINK SKLRFSLSDI NACGGGGGCQ ARGVLSEPPP GTHDYFQIHK QKHVATIVNF TPMPGPSFST TDEDYKPNWL EMVQKSQEYK ITLDLGKSIL TEEVVVSKSS VEAPPVAVLP PALVLPSAIN MKQDGSGYVN NDSEYNSVCE TASVASDLTR MYVSDEDDKP EPLRHVKPRD LAPDDASAEK RPRVQFTEHF // ID Q4RIM2_TETNG Unreviewed; 1200 AA. AC Q4RIM2; DT 19-JUL-2005, integrated into UniProtKB/TrEMBL. DT 19-JUL-2005, sequence version 1. DT 11-JUN-2014, entry version 27. DE SubName: Full=Chromosome 11 SCAF15043, whole genome shotgun sequence.; DE Flags: Fragment; GN ORFNames=GSTENG00033826001; OS Tetraodon nigroviridis (Spotted green pufferfish) (Chelonodon OS nigroviridis). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; OC Percomorpharia; Tetraodontiformes; Tetradontoidea; Tetraodontidae; OC Tetraodon. OX NCBI_TaxID=99883; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=15496914; DOI=10.1038/nature03025; RA Jaillon O., Aury J.-M., Brunet F., Petit J.-L., Stange-Thomann N., RA Mauceli E., Bouneau L., Fischer C., Ozouf-Costaz C., Bernot A., RA Nicaud S., Jaffe D., Fisher S., Lutfalla G., Dossat C., Segurens B., RA Dasilva C., Salanoubat M., Levy M., Boudet N., Castellano S., RA Anthouard V., Jubin C., Castelli V., Katinka M., Vacherie B., RA Biemont C., Skalli Z., Cattolico L., Poulain J., De Berardinis V., RA Cruaud C., Duprat S., Brottier P., Coutanceau J.-P., Gouzy J., RA Parra G., Lardier G., Chapple C., McKernan K.J., McEwan P., Bosak S., RA Kellis M., Volff J.-N., Guigo R., Zody M.C., Mesirov J., RA Lindblad-Toh K., Birren B., Nusbaum C., Kahn D., Robinson-Rechavi M., RA Laudet V., Schachter V., Quetier F., Saurin W., Scarpelli C., RA Wincker P., Lander E.S., Weissenbach J., Roest Crollius H.; RT "Genome duplication in the teleost fish Tetraodon nigroviridis reveals RT the early vertebrate proto-karyotype."; RL Nature 431:946-957(2004). RN [2] RP NUCLEOTIDE SEQUENCE. RG Genoscope; RG Whitehead Institute Centre for Genome Research; RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases. CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CAAE01015043; CAG11760.1; -; Genomic_DNA. DR STRING; 99883.ENSTNIP00000021413; -. DR eggNOG; NOG328380; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 4: Predicted; FT NON_TER 1200 1200 SQ SEQUENCE 1200 AA; 138378 MW; 09894228913C0E0D CRC64; MNCELLATCS ALGYLEGDTY HKEPDCLESV KDLIRYLRYE DDSRDVRQQL GAAQIVQNDL LPLIIQHGQD KTLFDACIRL MVNLTQPAML CFGKVPDDPV FRQHFLEVTS HLQAYKETFA SEKVFGILSE TLYSLLQLDW EQRQEEDNLL IERILLLVRN VLHVPADPCE EKKVDDDASV HDRLLWAIHI SGFDDLVKFL ASAQSEKQWS LHILEIITLM FRDQTPDALV SAGQSRSTEE KLRDSQELES LRQKEHAAKR SRTFQRGTRH SRFGGSYVVQ GLRSIGENDL IYHRNLHHVS SDLLQFKKHR RLGKEKMLPS LFFFSKFKNY THDTGKTVRR VPKRYRQAQE CKDQRRSALN VRLFLREFCV DFLENCYNHL MYLVKERLIR EQTEEHDETY YLWALSFFMA FNRGNGFHTD LVSETMSIRT FHFIERNLMK YYEMILTDRK EATSWSRRMH LALKAYQELL LNLNEMDHSQ DENIRQSSNI IKSNIFYMME YREIFLTLLR KYDETKQPQS YLQDLVESTH LFLRMLERFC TGRKNLMVQR KRVKRRKRRG RRTTHTHKYE THRVRKANQE LRNTNQLYLF CCVLYQLSAS VTEVSVPFDA TSETPLEEQR TEAMVRVQDA LVARLGPEAL GLLRAAREVW PEGDVFGSAD VEPDEELELL KQILHADLPR TTAEPAPEEE EEEDAAELEE EELESVQVSE SEFNFLDFIK RFANPAIVRP YILLLKTYSK NTPHTNHCIA RMLHRLAVNL KMDALLFQLS VFSVFNKILN DPAAAAYTEL VTFAKFVLKR FFALAAQNSK AYIELLFWKN VGAVREMTEG YSKDGARYRG DSAAVAEQHQ PHSAPGRDPV SAHGAGGYCK GPEETKVCIF LRRTFVCSAN LSFFFFGSRF FTKEKVLGLF FGPKNKNRSW RCSTKSSRTP TVGGKWSSGV PVQQSDGRLV FHRYTGEHPE EDHSQAFPRA SGGQAAQHGS GVRETRALQE EESRLSGEER REGNDGSVGE DEEEDESDES EEERDEEQEQ SHNGGRRRSL QLPAGRRVDV ASMVSALQQE GMSGPLLWLQ NCLYRTAEDR EEDGFSQAVP LLPLSEANEE AMETRSFQKL LRKIGIRAPA NEQEIFWRIP AKISASQLRS AAAALTPEPE GPGGDDKQRD CGTGESQAED EEEQEEEEEE AEGEQRAQAL RALLLARKRK // ID Q54KW8_DICDI Unreviewed; 1326 AA. AC Q54KW8; DT 24-MAY-2005, integrated into UniProtKB/TrEMBL. DT 24-MAY-2005, sequence version 1. DT 03-SEP-2014, entry version 41. DE SubName: Full=Timeless family protein; GN ORFNames=DDB_0215738, DDB_G0287103; OS Dictyostelium discoideum (Slime mold). OC Eukaryota; Amoebozoa; Mycetozoa; Dictyosteliida; Dictyostelium. OX NCBI_TaxID=44689; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=AX4; RX PubMed=15875012; DOI=10.1038/nature03481; RG The Dictyostelium discoideum Sequencing Consortium; RA Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., RA Sucgang R., Berriman M., Song J., Olsen R., Szafranski K., Xu Q., RA Tunggal B., Kummerfeld S., Madera M., Konfortov B.A., Rivero F., RA Bankier A.T., Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., RA Pilcher K., Chen G., Saunders D., Sodergren E.J., Davis P., RA Kerhornou A., Nie X., Hall N., Anjard C., Hemphill L., Bason N., RA Farbrother P., Desany B., Just E., Morio T., Rost R., Churcher C.M., RA Cooper J., Haydock S., van Driessche N., Cronin A., Goodhead I., RA Muzny D.M., Mourier T., Pain A., Lu M., Harper D., Lindsay R., RA Hauser H., James K.D., Quiles M., Madan Babu M., Saito T., RA Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D., RA Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., RA Quail M.A., Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., RA Sanders M., Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., RA Tivey A., Sugano S., White B., Walker D., Woodward J.R., Winckler T., RA Tanaka Y., Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., RA Cox E.C., Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., RA Kay R.R., Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., RA Kuspa A.; RT "The genome of the social amoeba Dictyostelium discoideum."; RL Nature 435:43-57(2005). CC -!- CAUTION: The sequence shown here is derived from an CC EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is CC preliminary data. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAFI02000096; EAL63916.1; -; Genomic_DNA. DR RefSeq; XP_637402.1; XM_632310.1. DR STRING; 44689.DDBDRAFT_0215738; -. DR EnsemblProtists; DDB0304884; DDB0304884; DDB_G0287103. DR GeneID; 8625934; -. DR KEGG; ddi:DDB_G0287103; -. DR dictyBase; DDB_G0287103; -. DR eggNOG; NOG328380; -. DR InParanoid; Q54KW8; -. DR KO; K03155; -. DR OMA; GEDCLEA; -. DR PhylomeDB; Q54KW8; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1326 AA; 153795 MW; 740C6157C94D12FC CRC64; MMDDDSGLIE ILGALGSYRY INDENEEVLN YNINNINKNI NSVGIDGKKL KKKAIENEDN ISKIFECGED CLEAARALYR MLNEDDDIDR SVFHFLGKNN IARSKLVPIL IAYPDNTNLV ITILKIFVKL TLQLPYHIES YDIPKQTLYT LNMKESFLNR ELIKTLLDIL KEPMINLGFS NGKSQDYIII ELVLTLIKNM LQIQDPISSQ TSIESEYRCH MHSNLIELLE EENILELFLV LAQNIHTNKV YKQISIYSLL LLEIFTLLLK NENPNEIWSS QEKNEENNDN GDDDDNNNDK KKKKILSEKD KSLINLLKKE KRLSTKLVSN GNRSRFIGTY TSYSEIEGKK IINKTLPDMA TVNSVRPTSL GNFSASLLAS RTKVIGERKK TASSLKVRLI LKSWAEQFLD GCYNTLMNTV VDEFAKENAQ ILDSDRLNFL MLTKFFTGFS LALLRYHSEK VEQLKKKKQL EKELDDMVVD KNLEPQSDDE GDEDIDAFTH DNIIGSLSST LSPSNFQFIF SSCSNYQMIK KHLSLEVAVS TLREMISLLN YMSVSPIEQY KQISLEMQST IYYDRDAFLK LIINLMRIYD PNHYSKSMML DLIDLSFTTV IMVENFCKQN NAIEIKSKRQ RSSKSLNSID DNTEAINQPT ENQDGTITDD GFPDEEEKED EYDSQIRNSM DFTSFMAEFA HSEVIKNLAL VLGGYHGNTT LINHQIIQLY KRIANDLELE PMFYQISLFY LFKNLLNDPL ISSSKSGDSK DLLEFINQIL SKYYKAVESN PSFLIDILIP KSRTDCFYLK TNDEDGDISQ QQQQQQQEQQ EFDENGIPIL KISKNTGRLK KKSNGDSDEG EVFLESDDDK DEYILQNIVS KMEDTLKRPE LIEKIKLLNK RKVGPKIIGW LQQHLLNAIV IRTKEKNNPS FTLYPLLYEG ECDGENFNNL ANVRQIFSLL KFGLPTSRNG FYTISSLKNY STNYLTAIYE TIKEALEQQT LEIQQKELKK QQRKLQPKQP RSKISSKGKK TIVAKFDKNG KRNPLYQSSD EEESNNESKS KSSSESESSS SESEVESEVE SEVESDNEKE EDKVNKEKKH STNNYKKEET DNEEKEEEKE EEEDRDKGEE DKEESDDEEI ENLKEKIQLK EKEKRDRKKE KKEKRKNKKR EEKEKKRNRK EKEKEHEEEE EEEEDEEKDE EEEEKEEMFS ENVFVNIEPI EKSVESKKKL KKILKKSNQD SDEDSDTIQS SKVKTILDSD SDEESNREDS FKNNKKDQDD NDKDITPNKR NKVLKRKNIS LSDDDEEDKE ESDNDKDIGS DEDQKTDKVS KKHKSN // ID Q5NIQ9_DROSI Unreviewed; 76 AA. AC Q5NIQ9; DT 01-FEB-2005, integrated into UniProtKB/TrEMBL. DT 01-FEB-2005, sequence version 1. DT 03-OCT-2012, entry version 13. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=TIM; OS Drosophila simulans (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7240; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=SIM1; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AJ748819; CAG38646.1; -; Genomic_DNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 76 76 SQ SEQUENCE 76 AA; 8595 MW; 5408C4D02C68F8DD CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIDGQN VRSDLIPLLE NAKDDA // ID Q5NIS7_DROME Unreviewed; 100 AA. AC Q5NIS7; DT 01-FEB-2005, integrated into UniProtKB/TrEMBL. DT 01-FEB-2005, sequence version 1. DT 24-JUL-2013, entry version 29. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=TIM; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CAV04, CAV14, CAV20, CAV56, GR05, GR101, GR103, HU151, and W6; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AJ748800; CAG38627.1; -; Genomic_DNA. DR EMBL; AJ748801; CAG38628.1; -; Genomic_DNA. DR EMBL; AJ748802; CAG38629.1; -; Genomic_DNA. DR EMBL; AJ748803; CAG38630.1; -; Genomic_DNA. DR EMBL; AJ748804; CAG38631.1; -; Genomic_DNA. DR EMBL; AJ748805; CAG38632.1; -; Genomic_DNA. DR EMBL; AJ748806; CAG38633.1; -; Genomic_DNA. DR EMBL; AJ748808; CAG38635.1; -; Genomic_DNA. DR EMBL; AJ748809; CAG38636.1; -; Genomic_DNA. DR PRIDE; Q5NIS7; -. DR ChiTaRS; ARHGEF5; drosophila. DR Bgee; Q5NIS7; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 100 100 SQ SEQUENCE 100 AA; 11517 MW; CD2E7551EE189DC7 CRC64; MSRVRQLHNH IWNNQNFDKV KSVMDWLLAT PQLYSAFSSL GCLEGDTYVV NPNALAILEE INYKLTYEDQ TLRTFRRAIG FGQNVRSDLI PLLENAKDDA // ID Q5NIT0_DROME Unreviewed; 76 AA. AC Q5NIT0; DT 01-FEB-2005, integrated into UniProtKB/TrEMBL. DT 01-FEB-2005, sequence version 1. DT 24-JUL-2013, entry version 22. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=TIM; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=W16; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AJ748798; CAG38625.1; -; Genomic_DNA. DR PRIDE; Q5NIT0; -. DR ChiTaRS; ARHGEF5; drosophila. DR Bgee; Q5NIT0; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 76 76 SQ SEQUENCE 76 AA; 8613 MW; 12FE49ECE2EDE4E7 CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDD // ID Q5NIT1_DROME Unreviewed; 77 AA. AC Q5NIT1; DT 01-FEB-2005, integrated into UniProtKB/TrEMBL. DT 01-FEB-2005, sequence version 1. DT 16-OCT-2013, entry version 30. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=TIM; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=CAV01, CAV06, CAV17, GR100, GR13, GR14, GR15, GR19, HU133, W11, RC W13, and W14; RX PubMed=17600215; DOI=10.1126/science.1138412; RA Tauber E., Zordan M., Sandrelli F., Pegoraro M., Osterwalder N., RA Breda C., Daga A., Selmin A., Monger K., Benna C., Rosato E., RA Kyriacou C.P., Costa R.; RT "Natural selection favors a newly derived timeless allele in RT Drosophila melanogaster."; RL Science 316:1895-1898(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AJ748796; CAG38623.1; -; Genomic_DNA. DR EMBL; AJ748797; CAG38624.1; -; Genomic_DNA. DR EMBL; AJ748799; CAG38626.1; -; Genomic_DNA. DR EMBL; AJ748807; CAG38634.1; -; Genomic_DNA. DR EMBL; AJ748810; CAG38637.1; -; Genomic_DNA. DR EMBL; AJ748811; CAG38638.1; -; Genomic_DNA. DR EMBL; AJ748812; CAG38639.1; -; Genomic_DNA. DR EMBL; AJ748813; CAG38640.1; -; Genomic_DNA. DR EMBL; AJ748814; CAG38641.1; -; Genomic_DNA. DR EMBL; AJ748815; CAG38642.1; -; Genomic_DNA. DR EMBL; AJ748816; CAG38643.1; -; Genomic_DNA. DR EMBL; AJ748817; CAG38644.1; -; Genomic_DNA. DR PRIDE; Q5NIT1; -. DR ChiTaRS; ARHGEF5; drosophila. DR Bgee; Q5NIT1; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 77 77 SQ SEQUENCE 77 AA; 8684 MW; EBB2FE49ECE2EDE4 CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDA // ID Q6DCJ5_XENLA Unreviewed; 883 AA. AC Q6DCJ5; DT 16-AUG-2004, integrated into UniProtKB/TrEMBL. DT 16-AUG-2004, sequence version 1. DT 11-JUL-2012, entry version 21. DE SubName: Full=TIMELESS protein; DE Flags: Fragment; GN Name=TIMELESS; OS Xenopus laevis (African clawed frog). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; OC Xenopus. OX NCBI_TaxID=8355; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. RC TISSUE=Ovary; RG NIH - Xenopus Gene Collection (XGC) project; RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BC078023; AAH78023.1; -; mRNA. DR UniGene; Xl.29613; -. DR HOVERGEN; HBG079258; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; FT NON_TER 883 883 SQ SEQUENCE 883 AA; 103221 MW; 5FA5967AEE0BCFE8 CRC64; MDLYMMNCEL LATCSALGFL EGDTYHKEPD CLESIKDLIR YLRHEDDTRD IRQQLGAAQI LQNDLVPLVI QHHNDKQLFD AVIRLMVNLT QPALLCFGKV PQDPTFRHHF LQIVSYLQAY KEAFADERLF GVLSEKLYDL LQMEWEQREE EHNLLIERIL LLVRNILHVP PDPEEEKSVD DDASIHDRVL WAIHMSGMDD LIKFLASSET EQQWSMHVLE TVSLMFRDQI AEHLAATGQA RSTAERDTDI KNLEILRQRE MAEKKNRALQ RGNRHSRFGG SYIVQGLKSI GDKDVIYHKG LQNFKNYTHD LGKEMRRVPK RKQQAKDTEA RRRSALNVRL FLKEFCIDFL ENCYNRLMYI VKDNLIREKA QQHDETYYLW SMAFFMGFNR LFHFKPELVS ETVSIRTFHF IEQNLTNYYE MMLTDKKEAT SWARRMHLAL KAYQELLSNV HEMDHSKEEA VRESSKIIKN NIFYLMEYRE LFLALFRKFD ETKQPRSFLK DLVETTHLFL KMLEKFCKGK QTVVVQNRRV KRKKKKSSVS GTKAAQPKSI EELEAIWTNV SEQLRTCTLD SANLPDSVVP FDAASEIPVE EQRAEALVRI QDGLFSGHAS EALVLLRSAR EVWPEGDVFG AAEIEPEEET ELLKQILFAD LPRSTQAEIE DLGEEEEEEE IEEEELTSVQ VSEKEFNVLD YMKRFANSNV VKTYVLLLKN YQQNSSHTNH CVAKMLHRIA YDLKMEALLF QLSVFCTFNK ILVDPAASAY KELVVFSKYI LNKFFSLAAT NNKAYVELLF WKNTNVIREM TEGYRKLGEE ESEGNRKRIK WTPEDDEELR SLYLQLKEVE DVDVVDNILA NLKPGTRTRK QVINHLVQMG LADSVKDFKK KKK // ID Q6L573_ORYSJ Unreviewed; 1226 AA. AC Q6L573; DT 05-JUL-2004, integrated into UniProtKB/TrEMBL. DT 05-JUL-2004, sequence version 1. DT 03-SEP-2014, entry version 46. DE SubName: Full=Os05g0210500 protein; DE SubName: Full=Putative uncharacterized protein OJ1008_D08.8; GN Name=OJ1008_D08.8; OrderedLocusNames=Os05g0210500; OS Oryza sativa subsp. japonica (Rice). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; Liliopsida; Poales; Poaceae; BEP clade; OC Ehrhartoideae; Oryzeae; Oryza. OX NCBI_TaxID=39947; RN [1] RP NUCLEOTIDE SEQUENCE. RA Chow T.-Y., Hsing Y.-I.C., Chen C.-S., Chen H.-H., Liu S.-M., RA Chao Y.-T., Chang S.-J., Chen H.-C., Chen S.-K., Chen T.-R., RA Chen Y.-L., Cheng C.-H., Chung C.-I., Han S.-Y., Hsiao S.-H., RA Hsiung J.-N., Hsu C.-H., Huang J.-J., Kau P.-I., Lee M.-C., Leu H.-L., RA Li Y.-F., Lin S.-J., Lin Y.-C., Wu S.-W., Yu C.-Y., Yu S.-W., RA Wu H.-P., Shaw J.-F.; RT "Oryza sativa BAC OJ1008_D08 genomic sequence."; RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RG International Rice Genome Sequencing Project; RA Matsumoto T., Wu J., Kanamori H., Katayose Y., Fujisawa M., Namiki N., RA Mizuno H., Yamamoto K., Antonio B.A., Baba T., Sakata K., Nagamura Y., RA Aoki H., Arikawa K., Arita K., Bito T., Chiden Y., Fujitsuka N., RA Fukunaka R., Hamada M., Harada C., Hayashi A., Hijishita S., Honda M., RA Hosokawa S., Ichikawa Y., Idonuma A., Iijima M., Ikeda M., Ikeno M., RA Ito K., Ito S., Ito T., Ito Y., Ito Y., Iwabuchi A., Kamiya K., RA Karasawa W., Kurita K., Katagiri S., Kikuta A., Kobayashi H., RA Kobayashi N., Machita K., Maehara T., Masukawa M., Mizubayashi T., RA Mukai Y., Nagasaki H., Nagata Y., Naito S., Nakashima M., Nakama Y., RA Nakamichi Y., Nakamura M., Meguro A., Negishi M., Ohta I., Ohta T., RA Okamoto M., Ono N., Saji S., Sakaguchi M., Sakai K., Shibata M., RA Shimokawa T., Song J., Takazaki Y., Terasawa K., Tsugane M., Tsuji K., RA Ueda S., Waki K., Yamagata H., Yamamoto M., Yamamoto S., Yamane H., RA Yoshiki S., Yoshihara R., Yukawa K., Zhong H., Yano M., Yuan Q., RA Ouyang S., Liu J., Jones K.M., Gansberger K., Moffat K., Hill J., RA Bera J., Fadrosh D., Jin S., Johri S., Kim M., Overton L., Reardon M., RA Tsitrin T., Vuong H., Weaver B., Ciecko A., Tallon L., Jackson J., RA Pai G., Aken S.V., Utterback T., Reidmuller S., Feldblyum T., RA Hsiao J., Zismann V., Iobst S., de Vazeille A.R., Buell C.R., Ying K., RA Li Y., Lu T., Huang Y., Zhao Q., Feng Q., Zhang L., Zhu J., Weng Q., RA Mu J., Lu Y., Fan D., Liu Y., Guan J., Zhang Y., Yu S., Liu X., RA Zhang Y., Hong G., Han B., Choisne N., Demange N., Orjeda G., RA Samain S., Cattolico L., Pelletier E., Couloux A., Segurens B., RA Wincker P., D'Hont A., Scarpelli C., Weissenbach J., Salanoubat M., RA Quetier F., Yu Y., Kim H.R., Rambo T., Currie J., Collura K., Luo M., RA Yang T., Ammiraju J.S.S., Engler F., Soderlund C., Wing R.A., RA Palmer L.E., de la Bastide M., Spiegel L., Nascimento L., Zutavern T., RA O'Shaughnessy A., Dike S., Dedhia N., Preston R., Balija V., RA McCombie W.R., Chow T., Chen H., Chung M., Chen C., Shaw J., Wu H., RA Hsiao K., Chao Y., Chu M., Cheng C., Hour A., Lee P., Lin S., Lin Y., RA Liou J., Liu S., Hsing Y., Raghuvanshi S., Mohanty A., Bharti A.K., RA Gaur A., Gupta V., Kumar D., Ravi V., Vij S., Kapur A., Khurana P., RA Khurana P., Khurana J.P., Tyagi A.K., Gaikwad K., Singh A., Dalal V., RA Srivastava S., Dixit A., Pal A.K., Ghazi I.A., Yadav M., Pandit A., RA Bhargava A., Sureshbabu K., Batra K., Sharma T.R., Mohapatra T., RA Singh N.K., Messing J., Nelson A.B., Fuks G., Kavchok S., Keizer G., RA Linton E., Llaca V., Song R., Tanyolac B., Young S., Ho-Il K., RA Hahn J.H., Sangsakoo G., Vanavichit A., de Mattos Luiz.A.T., RA Zimmer P.D., Malone G., Dellagostin O., de Oliveira A.C., Bevan M., RA Bancroft I., Minx P., Cordum H., Wilson R., Cheng Z., Jin W., RA Jiang J., Leong S.A., Iwama H., Gojobori T., Itoh T., Niimura Y., RA Fujii Y., Habara T., Sakai H., Sato Y., Wilson G., Kumar K., RA McCouch S., Juretic N., Hoen D., Wright S., Bruskiewich R., Bureau T., RA Miyao A., Hirochika H., Nishikawa T., Kadowaki K., Sugiura M., RA Burr B., Sasaki T.; RT "The map-based sequence of the rice genome."; RL Nature 436:793-800(2005). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Nipponbare; RX PubMed=16100779; DOI=10.1038/nature03895; RG International rice genome sequencing project (IRGSP); RT "The map-based sequence of the rice genome."; RL Nature 436:793-800(2005). RN [4] RP NUCLEOTIDE SEQUENCE. RG IRGSP(International Rice Genome Sequencing Project); RT "Oryza sativa nipponbare(GA3) genomic DNA, chromosome 5."; RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. RN [5] RP NUCLEOTIDE SEQUENCE. RG The Rice Annotation Project (RAP); RT "The Second Rice Annotation Project Meeting (RAP2)."; RL Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases. RN [6] RP NUCLEOTIDE SEQUENCE. RX PubMed=16381971; DOI=10.1093/nar/gkj094; RA Ohyanagi H., Tanaka T., Sakai H., Shigemoto Y., Yamaguchi K., RA Habara T., Fujii Y., Antonio B.A., Nagamura Y., Imanishi T., Ikeo K., RA Itoh T., Gojobori T., Sasaki T.; RT "The Rice Annotation Project Database (RAP-DB): hub for Oryza sativa RT ssp. japonica genome information."; RL Nucleic Acids Res. 34:D741-D744(2006). RN [7] RP NUCLEOTIDE SEQUENCE. RG The Rice Annotation Project (RAP); RA Itoh T., Tanaka T., Barrero R.A., Yamasaki C., Fujii Y., Hilton P.B., RA Antonio B.A., Aono H., Apweiler R., Bruskiewich R., Bureau T., RA Burr F., Costa de Oliveira A., Fuks G., Habara T., Haberer G., Han B., RA Harada E., Hiraki A.T., Hirochika H., Hoen D., Hokari H., Hosokawa S., RA Hsing Y., Ikawa H., Ikeo K., Imanishi T., Ito Y., Jaiswal P., RA Kanno M., Kawahara Y., Kawamura T., Kawashima H., Khurana J.P., RA Kikuchi S., Komatsu S., Koyanagi K.O., Kubooka H., Lieberherr D., RA Lin Y.C., Lonsdale D., Matsumoto T., Matsuya A., McCombie W.R., RA Messing J., Miyao A., Mulder N., Nagamura Y., Nam J., Namiki N., RA Numa H., Nurimoto S., O'donovan C., Ohyanagi H., Okido T., Oota S., RA Osato N., Palmer L.E., Quetier F., Raghuvanshi S., Saichi N., RA Sakai H., Sakai Y., Sakata K., Sakurai T., Sato F., Sato Y., RA Schoof H., Seki M., Shibata M., Shimizu Y., Shinozaki K., Shinso Y., RA Singh N.K., Smith-White B., Takeda J., Tanino M., Tatusova T., RA Thongjuea S., Todokoro F., Tsugane M., Tyagi A.K., Vanavichit A., RA Wang A., Wing R.A., Yamaguchi K., Yamamoto M., Yamamoto N., Yu Y., RA Zhang H., Zhao Q., Higo K., Burr B., Gojobori T., Sasaki T.; RT "Curated Genome Annotation of Oryza sativa ssp. japonica and RT Comparative Genome Analysis with Arabidopsis thaliana."; RL Genome Res. 17:175-183(2007). RN [8] RP GENOME REANNOTATION. RC STRAIN=cv. Nipponbare; RX PubMed=18089549; DOI=10.1093/nar/gkm978; RG The rice annotation project (RAP); RT "The rice annotation project database (RAP-DB): 2008 update."; RL Nucleic Acids Res. 36:D1028-D1033(2008). RN [9] RP NUCLEOTIDE SEQUENCE. RG The Rice Annotation Project (RAP); RA Tanaka T., Antonio B.A., Kikuchi S., Matsumoto T., Nagamura Y., RA Numa H., Sakai H., Wu J., Itoh T., Sasaki T., Aono R., Fujii Y., RA Habara T., Harada E., Kanno M., Kawahara Y., Kawashima H., Kubooka H., RA Matsuya A., Nakaoka H., Saichi N., Sanbonmatsu R., Sato Y., Shinso Y., RA Suzuki M., Takeda J., Tanino M., Todokoro F., Yamaguchi K., RA Yamamoto N., Yamasaki C., Imanishi T., Okido T., Tada M., Ikeo K., RA Tateno Y., Gojobori T., Lin Y.C., Wei F.J., Hsing Y.I., Zhao Q., RA Han B., Kramer M.R., McCombie R.W., Lonsdale D., O'Donovan C.C., RA Whitfield E.J., Apweiler R., Koyanagi K.O., Khurana J.P., RA Raghuvanshi S., Singh N.K., Tyagi A.K., Haberer G., Fujisawa M., RA Hosokawa S., Ito Y., Ikawa H., Shibata M., Yamamoto M., RA Bruskiewich R.M., Hoen D.R., Bureau TE., Namiki N., Ohyanagi H., RA Sakai Y., Nobushima S., Sakata K., Barrero R.A., Sato Y., Souvorov A., RA Smith-White B., Tatusova T., An S., An G., OOta S., Fuks G., RA Messing J., Christie K.R., Lieberherr D., Kim H., Zuccolo A., RA Wing R.A., Nobuta K., Green P.J., Lu C., Meyers BC., Chaparro C., RA Piegu B., Panaud O., Echeverria M.; RT "The Rice Annotation Project Database (RAP-DB): 2008 update."; RL Nucleic Acids Res. 36:D1028-D1033(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AC104705; AAT44176.1; -; Genomic_DNA. DR EMBL; AP008211; BAF16829.1; -; Genomic_DNA. DR RefSeq; NP_001054915.1; NM_001061450.1. DR UniGene; Os.56612; -. DR STRING; 39947.LOC_Os05g11980.1; -. DR GeneID; 4338095; -. DR KEGG; osa:4338095; -. DR KO; K03155; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1226 AA; 137451 MW; 7383A2D618A5FEC9 CRC64; MDSAALSLTC AGLGGAEEDD GGAVVGYAKG EHCLDNLKDL QRFLRRDDPQ RREVFKQVCK WKIASRDLVP IIENYQADRN LVITAVKVLV FLTMPVEPSS ENVAQQIEYL WDLKAALTRN VAMAVIVSLL EDPLDHLERA SFTEDDWKLV QLVLTLFRNI LAIQEITLGQ KASGEATQLL CLADSFLELM FQENVMDLIL VLTQHMDEPS GYLQQENLLL LEIFHYLFLG RDPELIARAS TAGSKDGSKS LCKGNPNSAS ANSLRKIRNV QRGPQKRIAW DNELLYTPRE GTMEMIRNFL EQFLSGGYNG ETTIFHFHVK LGITQCLPVL MQSVCDDIVK EHHSIQKSDI TTFFKVARFV LAFQHEKASN AQKSNAAVQL PEASPSDHLD DNLPFLGDIC GPVAATLNEG MFNLVISRWR EAYDSLKETH DYKTLSAAGS LMKNMIDMVY LVLKVLPDDS RESQTARVLL YKLFYDQTEQ GLTQFLLNLF RSFDTHKQPK SDLADLLGTI HIMLQLMEKL QARGALRVAK RTRKGRKKKA SKNKIENTNL NAEKMEQSNV DSTDGTKSAL ESLPDLKNVD SVAEPPLTEQ EKVVSNGMDA PDELAGTSVN LDSTSHCEGE PSRADNGELK GNLIDEEDGT SDSSLDDQPP ATSEVDFNVS RLISTLANNS VVQNICWLLK HYKSNSFRTN HYIICMLRRF CEDLELAPML YQLSLLTTFY DILADEKSSN SKEYTNIVNF LSKIVRKMLR VMKKQPLLFV DVLFWKTRKE CHCIDADALL SDITKDATNK GGEIGSSKGW RGSINIADSL GDDEVDLVIP HEPYNADKDD DSSSGEHEDV SKRSMGATNK SNRILSFSDS EADDNDSSIQ IEKNRNTVSR GSQNSEAPKR RGRSIFSEEQ EKLMRDLYEK YKDDRKCTHL IAEALDPSGK ISSVQVYRKL TQLGLRNAMK RRTKVPEAPL SAQELATQTD QMLGEHNCDP KPETTRRRRK RQNVSHASYE DNTTDGKSSD EETLQAIKSR TKNKKVPLVG FSPSTSQHQD GLADPDSDDE TIGSMLRSGK KKRLLTPDNA MNIEKHQESP DSTNTSNYSP EISQKQEALQ DTYSGDEIID SMHRSGKKKR LLKSGFAANT QEHEEPLKNI GQDDETISSK DNLHHGLNSS NNSGGAGETE LLDDFIEPEL DNVENTEQRV IDDINITESG DMESSFADQK PGLKRRHKLV IDDDDD // ID Q7YSH7_DROAE Unreviewed; 164 AA. AC Q7YSH7; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 15. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340310; AAQ20963.1; -; Genomic_DNA. DR EMBL; AY340319; AAQ20972.1; -; Genomic_DNA. DR EMBL; AY340327; AAQ20980.1; -; Genomic_DNA. DR EMBL; AY340331; AAQ20984.1; -; Genomic_DNA. DR EMBL; AY340335; AAQ20988.1; -; Genomic_DNA. DR EMBL; AY340341; AAQ20994.1; -; Genomic_DNA. DR EMBL; AY340342; AAQ20995.1; -; Genomic_DNA. DR EMBL; AY340348; AAQ21001.1; -; Genomic_DNA. DR EMBL; AY340360; AAQ21013.1; -; Genomic_DNA. DR EMBL; AY340370; AAQ21023.1; -; Genomic_DNA. DR EMBL; AY340371; AAQ21024.1; -; Genomic_DNA. DR EMBL; AY340378; AAQ21031.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18351 MW; F17518B2D4E51BAC CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YSR4_DROAE Unreviewed; 164 AA. AC Q7YSR4; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 17. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=G96.21, G96.47, ML97.3, ML97.4.2, and ML97.5; RX PubMed=18482259; DOI=10.1111/j.1365-294X.2008.03796.x; RA Morales-Hojas R., Vieira C.P., Vieira J.; RT "Inferring the evolutionary history of Drosophila americana and RT Drosophila novamexicana using a multilocus approach and the influence RT of chromosomal rearrangements in single gene analyses."; RL Mol. Ecol. 17:2910-2926(2008). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340308; AAQ20961.1; -; Genomic_DNA. DR EMBL; AY340309; AAQ20962.1; -; Genomic_DNA. DR EMBL; AY340311; AAQ20964.1; -; Genomic_DNA. DR EMBL; AY340313; AAQ20966.1; -; Genomic_DNA. DR EMBL; AY340314; AAQ20967.1; -; Genomic_DNA. DR EMBL; AY340315; AAQ20968.1; -; Genomic_DNA. DR EMBL; AY340316; AAQ20969.1; -; Genomic_DNA. DR EMBL; AY340317; AAQ20970.1; -; Genomic_DNA. DR EMBL; AY340318; AAQ20971.1; -; Genomic_DNA. DR EMBL; AY340320; AAQ20973.1; -; Genomic_DNA. DR EMBL; AY340321; AAQ20974.1; -; Genomic_DNA. DR EMBL; AY340322; AAQ20975.1; -; Genomic_DNA. DR EMBL; AY340323; AAQ20976.1; -; Genomic_DNA. DR EMBL; AY340324; AAQ20977.1; -; Genomic_DNA. DR EMBL; AY340325; AAQ20978.1; -; Genomic_DNA. DR EMBL; AY340326; AAQ20979.1; -; Genomic_DNA. DR EMBL; AY340328; AAQ20981.1; -; Genomic_DNA. DR EMBL; AY340329; AAQ20982.1; -; Genomic_DNA. DR EMBL; AY340330; AAQ20983.1; -; Genomic_DNA. DR EMBL; AY340332; AAQ20985.1; -; Genomic_DNA. DR EMBL; AY340333; AAQ20986.1; -; Genomic_DNA. DR EMBL; AY340334; AAQ20987.1; -; Genomic_DNA. DR EMBL; AY340337; AAQ20990.1; -; Genomic_DNA. DR EMBL; AY340338; AAQ20991.1; -; Genomic_DNA. DR EMBL; AY340339; AAQ20992.1; -; Genomic_DNA. DR EMBL; AY340340; AAQ20993.1; -; Genomic_DNA. DR EMBL; AY340343; AAQ20996.1; -; Genomic_DNA. DR EMBL; AY340344; AAQ20997.1; -; Genomic_DNA. DR EMBL; AY340345; AAQ20998.1; -; Genomic_DNA. DR EMBL; AY340346; AAQ20999.1; -; Genomic_DNA. DR EMBL; AY340347; AAQ21000.1; -; Genomic_DNA. DR EMBL; AY340349; AAQ21002.1; -; Genomic_DNA. DR EMBL; AY340350; AAQ21003.1; -; Genomic_DNA. DR EMBL; AY340351; AAQ21004.1; -; Genomic_DNA. DR EMBL; AY340352; AAQ21005.1; -; Genomic_DNA. DR EMBL; AY340353; AAQ21006.1; -; Genomic_DNA. DR EMBL; AY340355; AAQ21008.1; -; Genomic_DNA. DR EMBL; AY340358; AAQ21011.1; -; Genomic_DNA. DR EMBL; AY340359; AAQ21012.1; -; Genomic_DNA. DR EMBL; AY340364; AAQ21017.1; -; Genomic_DNA. DR EMBL; AY340365; AAQ21018.1; -; Genomic_DNA. DR EMBL; AY340366; AAQ21019.1; -; Genomic_DNA. DR EMBL; AY340367; AAQ21020.1; -; Genomic_DNA. DR EMBL; AY340368; AAQ21021.1; -; Genomic_DNA. DR EMBL; AY340372; AAQ21025.1; -; Genomic_DNA. DR EMBL; AY340373; AAQ21026.1; -; Genomic_DNA. DR EMBL; AY340374; AAQ21027.1; -; Genomic_DNA. DR EMBL; AY340375; AAQ21028.1; -; Genomic_DNA. DR EMBL; AY340376; AAQ21029.1; -; Genomic_DNA. DR EMBL; AY340377; AAQ21030.1; -; Genomic_DNA. DR EMBL; AY340379; AAQ21032.1; -; Genomic_DNA. DR EMBL; AY340381; AAQ21034.1; -; Genomic_DNA. DR EMBL; EU545841; ACD67952.1; -; Genomic_DNA. DR EMBL; EU545842; ACD67953.1; -; Genomic_DNA. DR EMBL; EU545843; ACD67954.1; -; Genomic_DNA. DR EMBL; EU545844; ACD67955.1; -; Genomic_DNA. DR EMBL; EU545845; ACD67956.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18321 MW; 5E18B5040F88B61A CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YST7_DROAE Unreviewed; 164 AA. AC Q7YST7; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 13. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340361; AAQ21014.1; -; Genomic_DNA. DR EMBL; AY340369; AAQ21022.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18420 MW; 3270992E8FCCB61E CRC64; VVEYMKHILE WDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YU23_DROME Unreviewed; 787 AA. AC Q7YU23; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 26-JUN-2013, entry version 30. DE SubName: Full=RE03551p; DE SubName: Full=RE03647p; GN Name=timeout; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley; RA Stapleton M., Brokstein P., Hong L., Agbayani A., Carlson J., RA Champe M., Chavez C., Dorsett V., Dresnek D., Farfan D., Frise E., RA George R., Gonzalez M., Guarin H., Kronmiller B., Li P., Liao G., RA Miranda A., Mungall C.J., Nunoo J., Pacleb J., Paragas V., Park S., RA Patel S., Phouanenavong S., Wan K., Yu C., Lewis S.E., Rubin G.M., RA Celniker S.; RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Berkeley; RA Stapleton M., Carlson J., Chavez C., Frise E., George R., Pacleb J., RA Park S., Wan K., Yu C., Rubin G.M., Celniker S.; RL Submitted (MAY-2005) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BT010028; AAQ22497.1; -; mRNA. DR EMBL; BT022088; AAY33504.1; -; mRNA. DR PaxDb; Q7YU23; -. DR PRIDE; Q7YU23; -. DR eggNOG; NOG328380; -. DR Bgee; Q7YU23; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 787 AA; 91062 MW; D05C27129043D9FA CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFRGQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV VRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGRGA SRKKKQAATK SKPPAAPQPT EEELSSKWAE LATEVCSLLS TELEMPEDEQ PLPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MSNITTVESE DKENEKDQKQ DEYEDEDDDL DNEEYEEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL KAAVTILHRI AYGCKCAGML FQAKLFRIFQ QVFSVERDVH QEERAAWPSL WCANLSR // ID Q7YU98_DROAE Unreviewed; 164 AA. AC Q7YU98; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 14. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340380; AAQ21033.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18363 MW; FC18ABABE0B1918C CRC64; VXEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YU99_DROAE Unreviewed; 157 AA. AC Q7YU99; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 13. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340363; AAQ21016.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 157 157 SQ SEQUENCE 157 AA; 17434 MW; B4AAF07E9AD1DE51 CRC64; ILESDPKLSP HKCDQINNCL LLLRNILHIP ESHAHFLMPR LQSGGGHQVS MQNTILWNLF IQSIDKLLLY LMTCPQRSLW GVTMVQLIAL IYKDQHVSTL QKLLNLWFEA SLSESSDDNE SNTTPPKQAS GDSSPMLTSD PTSDSSDNGS GGKKESC // ID Q7YUA0_DROAE Unreviewed; 164 AA. AC Q7YUA0; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 13. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340362; AAQ21015.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18381 MW; F17518B2C0B45EAC CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQTSGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YUA1_DROAE Unreviewed; 164 AA. AC Q7YUA1; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 14. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340357; AAQ21010.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18317 MW; F6DC6085D388ABDB CRC64; VVEYMKHILE SXPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q7YUA2_DROAE Unreviewed; 164 AA. AC Q7YUA2; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 15. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340356; AAQ21009.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18320 MW; F17518B5BD351BAC CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGX NESC // ID Q7YUA3_DROAE Unreviewed; 164 AA. AC Q7YUA3; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 15. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340354; AAQ21007.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18405 MW; F17518B2D4E5093C CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GSGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSXGK KESC // ID Q7YUA4_DROAE Unreviewed; 164 AA. AC Q7YUA4; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 14. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340336; AAQ20989.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18304 MW; 5E18B51DDF88B61A CRC64; VVEYMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK XESC // ID Q7YUA5_DROAE Unreviewed; 164 AA. AC Q7YUA5; DT 01-OCT-2003, integrated into UniProtKB/TrEMBL. DT 01-OCT-2003, sequence version 1. DT 06-FEB-2013, entry version 14. DE SubName: Full=Timeless protein; DE Flags: Fragment; GN Name=tim; OS Drosophila americana (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=40366; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=14668385; RA McAllister B.F.; RT "Sequence differentiation associated with an inversion on the neo-X RT chromosome of Drosophila americana."; RL Genetics 165:1317-1328(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY340312; AAQ20965.1; -; Genomic_DNA. DR FlyBase; FBgn0064752; Dame\tim. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 4: Predicted; FT NON_TER 1 1 FT NON_TER 164 164 SQ SEQUENCE 164 AA; 18269 MW; 4BF7EB0A1538B7B1 CRC64; VVEXMKHILE SDPKLSPHKC DQINNCLLLL RNILHIPESH AHFLMPRLQS GGGHQVSMQN TILWNLFIQS IDKLLLYLMT CPQRSLWGVT MVQLIALIYK DQHVSTLQKL LNLWFEASLS ESSDDNESNT TPPKQASGDS SPMLTSDPTS DSSDNGSGGK KESC // ID Q8INH7_DROME Unreviewed; 1384 AA. AC Q8INH7; DT 01-MAR-2003, integrated into UniProtKB/TrEMBL. DT 01-JUN-2003, sequence version 2. DT 11-JUN-2014, entry version 76. DE SubName: Full=Timeout; GN Name=timeout; ORFNames=CG7855, Dmel_CG7855; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537568; RA Celniker S.E., Wheeler D.A., Kronmiller B., Carlson J.W., Halpern A., RA Patel S., Adams M., Champe M., Dugan S.P., Frise E., Hodgson A., RA George R.A., Hoskins R.A., Laverty T., Muzny D.M., Nelson C.R., RA Pacleb J.M., Park S., Pfeiffer B.D., Richards S., Sodergren E.J., RA Svirskas R., Tabor P.E., Wan K., Stapleton M., Sutton G.G., Venter C., RA Weinstock G., Scherer S.E., Myers E.W., Gibbs R.A., Rubin G.M.; RT "Finishing a whole-genome shotgun: release 3 of the Drosophila RT melanogaster euchromatic genome sequence."; RL Genome Biol. 3:RESEARCH0079-RESEARCH0079(2002). RN [3] RP GENOME REANNOTATION. RC STRAIN=Berkeley; RX PubMed=12537572; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537573; RA Kaminker J.S., Bergman C.M., Kronmiller B., Carlson J., Svirskas R., RA Patel S., Frise E., Wheeler D.A., Lewis S.E., Rubin G.M., RA Ashburner M., Celniker S.E.; RT "The transposable elements of the Drosophila melanogaster euchromatin: RT a genomics perspective."; RL Genome Biol. 3:RESEARCH0084-RESEARCH0084(2002). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=12537574; RA Hoskins R.A., Smith C.D., Carlson J.W., Carvalho A.B., Halpern A., RA Kaminker J.S., Kennedy C., Mungall C.J., Sullivan B.A., Sutton G.G., RA Yasuhara J.C., Wakimoto B.T., Myers E.W., Celniker S.E., Rubin G.M., RA Karpen G.H.; RT "Heterochromatic sequences in a Drosophila whole-genome shotgun RT assembly."; RL Genome Biol. 3:RESEARCH0085-RESEARCH0085(2002). RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=16110336; DOI=10.1371/journal.pcbi.0010022; RA Quesneville H., Bergman C.M., Andrieu O., Autard D., Nouaud D., RA Ashburner M., Anxolabehere D.; RT "Combined evidence annotation of transposable elements in genome RT sequences."; RL PLoS Comput. Biol. 1:166-175(2005). RN [7] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=17569856; DOI=10.1126/science.1139815; RA Smith C.D., Shu S., Mungall C.J., Karpen G.H.; RT "The Release 5.1 annotation of Drosophila melanogaster RT heterochromatin."; RL Science 316:1586-1591(2007). RN [8] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=17569867; DOI=10.1126/science.1139816; RA Hoskins R.A., Carlson J.W., Kennedy C., Acevedo D., Evans-Holm M., RA Frise E., Wan K.H., Park S., Mendez-Lago M., Rossi F., Villasante A., RA Dimitri P., Karpen G.H., Celniker S.E.; RT "Sequence finishing and mapping of Drosophila melanogaster RT heterochromatin."; RL Science 316:1625-1628(2007). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AE014297; AAF54908.3; -; Genomic_DNA. DR RefSeq; NP_524341.3; NM_079617.3. DR UniGene; Dm.2433; -. DR MINT; MINT-997109; -. DR EnsemblMetazoa; FBtr0082712; FBpp0082180; FBgn0038118. DR GeneID; 41615; -. DR KEGG; dme:Dmel_CG7855; -. DR UCSC; CG7855-RA; d. melanogaster. DR CTD; 41615; -. DR FlyBase; FBgn0038118; timeout. DR GeneTree; ENSGT00390000015124; -. DR InParanoid; Q8INH7; -. DR KO; K03155; -. DR OMA; CDAYEAG; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; Q8INH7; -. DR GenomeRNAi; 41615; -. DR NextBio; 824654; -. DR PRO; PR:Q8INH7; -. DR Bgee; Q8INH7; -. DR GO; GO:0000077; P:DNA damage checkpoint; IMP:FlyBase. DR GO; GO:0009649; P:entrainment of circadian clock; IMP:FlyBase. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1384 AA; 159363 MW; 8CA255EDD6C72FF5 CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGRGA SRKKKQAATK SKPPAAPQPT EEELSSKWAE LATEVCSLLS TELEMPEDEQ PLPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MSNITTVESE DKENEKDQKQ DEYEDEDDDL DNEEYEEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL KAAVTILHRI AYGCKCAGML FQAKLFRIFQ QVFSVERDVH QEELRRLAIF VVRKFVEVAP TNPKIYAELL FYKGIREANE LESGYCDAYE AGTKGAWTEE QESELRFLFE ENQRNPETDK DVIDWILDNL VDKTRNRRTV LKKLKELGLL FKAPTKRSTK SAQSGKNVWQ PEEDDELRSL YDQHRIEPDC LERLVNEFAE RRSKQQIIKR MLQIHLIADK SEILPAKKGR GKDKPKKDVE MEGEGDEFDF AEEPMFEDQG YKKPKSKPKK VQKRQMVRTP LDVGTIRALI GQVDSEKYQS AIEWLQECLQ DASEDTEEAV EDDDGVPLLP LMENQKNAME DGDFQKVLVA LGMQPPISGM EAYWRIPIYL NSADLILRSK ILAGEEVDAE PEDEAADDED GEEAEESDEE EDFLEKHSRQ RKENIATQQQ RKLDSLMFNQ SDDETEQRAP PKAKDKPKAS EKKAKRKVKG KAKESKDCND DGTDKAELEK PNTDDLFNQL RAKRATKIKL SDMALNESTN AAQEADDDAF NFNSEDYRAR LLELEDEEQN SKDADENGGD KENITNKSLQ RARRVNVIDS DSDNDDDGAL PADKTNKRPR SDDDGDSGHM DANAEEDSDE EANFLARKKP AKVDGEPAKR RRLAIIDDDD EDDF // ID Q8MML1_9MUSC Unreviewed; 1356 AA. AC Q8MML1; DT 01-OCT-2002, integrated into UniProtKB/TrEMBL. DT 04-DEC-2007, sequence version 2. DT 03-OCT-2012, entry version 20. DE SubName: Full=Timeless protein; GN Name=timeless; OS Chymomyza costata. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Chymomyza. OX NCBI_TaxID=76946; RN [1] RP NUCLEOTIDE SEQUENCE. RC STRAIN=Sapporo; TISSUE=Adult head; RA Pavelka J., Shimada K., Kostal V.; RT "TIMELESS: A link between fly's circadian and photoperiodic clock?"; RL Eur. J. Entomol. 100:255-265(2003). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB073724; BAB91179.2; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1356 AA; 153070 MW; B3ADD20C58800688 CRC64; MDWLLATPQL HSAFSSLGAL VGDTYVVSPD ALAILEEINY KLIYEDQTLR TFRRAIAFGQ NVRSDLIPVL ENTKDDAVLE SVIRLLVNLT VPVECLFSVD VMYRTEMGRH TIFELNKLLY NSKEAFTDPK STKSVVEYMK HILDSETKLS PQKCDQINNC LLLLRNILHI PETNANFIKP MLQSSSRHGT SMQNTILWNL FIQSIDKMLL YLMTCPQRAL WGVTMVQLIA LIYKDQHIST LQKLLNLWFE ASLSESSEDN ESNTTPPKQG SGDYSPMLTS DPTSDCSEKD GDERRQTLRE GTDATLQEVS RKGQEYQDAM FGVPAKKLEC AETSSEVTSE APSSPQQHWK VTEPPEPEKE MAMAAITEQQ ASMIMQLTQP ADNAKTTTNT TCTANQERFK QPPPLPVRPL TCTQAEKLGE MADETYPKHV SAVKRGQKSP HSGQLHLTKG KCFPQKRECA SSQSELSDCG YGTQVENQES ISTSSNDDDA PQGKPQHQKP PCNTKPRNKQ RNIVTPLDKK EQRRKKLVKR SKSNLINMKG LCQHTPTDDD ISNLLKEFTV DFLLKGYNYL VKVLHLHITS NAKVSIDTSH FFWLVAYFLK FAAQLELDME HIDTILNFDV LTYLTSEGVS LCEQLELNAR QEGSDLKPYL RRMHLVVTAI REFLQAIETY SKVTHLSEDD RTQLLKPQIQ ISAATDLRSL FVLLLRRFNP SIHSKQYLQD LVVTNHKLML VLDRAAKLEG GQSVYLTEHL LQFATPEVMH YYGILLEDFN YNGEFLNDCI FTMMHHIGGD LKQIGVLFQP IILKTFSRLW ETDNGLCDDW TDLIAYVIRK FMSTPPKSPL ILPNTSLTEM TKEHNLQNNL FTWTQEDMDT LYWYYVQSKK SNDVVGKIVK LFSNNGNKLK SRISIIQQLL AQDMINLLEY DDLMKFEEAE YQRSLLNTPT SGTNASGLES GKPSNDTQML LDLIIKDNKQ QHLIWLQQLL LECCYIKLKL RSGNSCSTDA IMEPVAYHCI LMQKSIPIVQ WNNDQSAIML YQPFVLLLHK LGIQLPADAG TIFARIPDYW TPETMYGVAK KLGTLDKLTL KFDPIELEVA SSTTPRHCMK SLNSLSSVSS LDVDMPELEE LPLIPEVDAA IEKAHEIFVA PKAKNCNSII RYTPDVTPAV PNWLQLVMRS KCIQQSVPSR PATDISDCTG ADDESMHSSS QQAPTQQLLA TSNSSNVNHA TTLGCQPSII GAHNDNSSSS GCGGTDSSQS MAAVVSNTRT TGNNTPRKTA EAISRKTTHM YEDAAMKSFQ RLQATNSHFS RANNLEQQYS ALVASIYENE MANCDNISMA SDLEHMYVSD EEDTHENHEQ RVPYYH // ID Q8SQI2_SARCR Unreviewed; 1378 AA. AC Q8SQI2; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 01-JUN-2002, sequence version 1. DT 03-OCT-2012, entry version 18. DE SubName: Full=TIMELESS; DE Flags: Fragment; GN Name=tim; OS Sarcophaga crassipalpis. OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Oestroidea; Sarcophagidae; Sarcophaga; Liopygia. OX NCBI_TaxID=59312; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Head; RX PubMed=12770058; DOI=10.1016/S0022-1910(02)00108-7; RA Goto S.G., Denlinger D.L.; RT "Short-day and long-day expression patterns of genes involved in the RT flesh fly clock mechanism: period, timeless, cycle and cryptochrome."; RL J. Insect Physiol. 48:803-816(2002). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB079534; BAB85471.1; -; mRNA. DR EMBL; AB079535; BAB85472.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 SQ SEQUENCE 1378 AA; 154991 MW; 9D8BD158834302BC CRC64; LESDSKLSPK KCDQINNCLL LLRNILHIPE SNVNYLMSST SHNQPGGSHP VSMQRAILWN LFIQSIDKLL LYLMTCPQRA FWGVTMVQLI ALIYKDQHVS TLQKLLNLWF EASLSESSED NESNTSPPKQ GSCDSSPMLT SDPTSDSSDN GSAGSKNGNS EDRRQALREE TEATLQEVSR KGQEYQDSML RVPADKVDSS EGASDVGNTD CEEVFSVNPE QPSSVDDEEA AQSNGTVIHP SNNLETDRIE EIPTSTSQFS EEIITTTTTN KNEQPAEQDS STSNLADASN FMPPPPLPLR GSAPVSKNRC VDADLMNATT KACQKSPHSG HVKLTMGNCG PQKRECPSSQ SELSDCGYGT QVENQESIST SSNDDDSPQG KPQHQKPPCS SKARNKHRIV LTAIDNKELR RKKLVKRSKS SLINMKGLVQ HTPTDEDISN LLKEFTVDFL LKGYGYLVED LHTQLLTNRK IPIDTSHFFW LVTYFLKFAA QLELDMEHVN TILTFNVISY LTYEGVMLCE QLELNSRQEG SDLKPYLRRL HLVVTAIREF LQAIETYKKV THLSDEDRER LRILQQQISS TEDLRNLFVL LLRRFNPSLH TKQYLQDLVV TNHILLLILD SVTKSNCNIH IKMIEHISQF ATLEIMNYYG MLLDDFNNNG EFVNDCIFTM MHHIGGDLGQ VGTLFQPVIL KTYSRIWEAD YELCDDWSDL IEYVIHKFMN TPQKSPLTLP STSLTELTKE HNMETTVCTW TQEEMDTLYW YYVQSKKNND IVGKIVKLFS NNGNKQKSRI SIIQQLLQQD IITLVEYDDL MKFEDAEYQR TLLTTPTSGT TESGIEIKDT SQKGKPSDDV QILRDLIIKE NKQQHLVWLQ KLLLECCYVK LILRNNPLRE DHQNLTYILE PVAYHCILKN KSIPVVQWNN EQATTMLYQP FVLLLHKLGF QLPADAGSVF ARIPDFWTPE TMFNLAKKLG SLEKLPIKFD THQFDVINHM EMPDSSRSQY EASTTTRNSL SSMSSLEVDL NDSDELAPIP EVDDILEKTS QTCEIFAMPN AKQCNSIIRY TPKPTTLPTI PNWLQLVMRS KCNNANSSTS NAAAATASLA NLATNACNES DIWMSNNNSK SNDQTTSLPG NSAASNAVTT SIAIKESVSS LAETKVPTNA NSGSNSSTLT PTPTTTVTTT TLAIPFPTTI LTPSTAAVTA LVTPASLVNI TKMPNAANTT ETVPLATSAT SLAVSFKDYQ QQLHHNSNKN NFNNQLQQQL LHHEQQQQQQ QQQQQQQDQQ YHQQQQQQQQ QQQHHITYIN HSDDDDSAMK SLERNDSLAS SGFYTRSGSG NLEQELCAMV ASAYEEENAN LDSASVASDL TRMYVSDEEH EYRVAHYH // ID Q8TA55_SARBU Unreviewed; 1590 AA. AC Q8TA55; DT 01-JUN-2002, integrated into UniProtKB/TrEMBL. DT 17-OCT-2006, sequence version 2. DT 03-OCT-2012, entry version 19. DE SubName: Full=Timeless; GN Name=TIM; OS Sarcophaga bullata (Grey flesh fly) (Neobellieria bullata). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Oestroidea; Sarcophagidae; Neobellieria. OX NCBI_TaxID=7385; RN [1] RP NUCLEOTIDE SEQUENCE. RC TISSUE=Head; RX PubMed=17054977; DOI=10.1016/j.jinsphys.2006.09.003; RA Goto S.G., Han B., Denlinger D.L.; RT "A nondiapausing variant of the flesh fly, Sarcophaga bullata, that RT shows arrhythmic adult eclosion and elevated expression of two RT circadian clock genes, period and timeless."; RL J. Insect Physiol. 52:1213-1218(2006). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB080235; BAB85487.2; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1590 AA; 178090 MW; 87236D452D5993D4 CRC64; MDWLLATPQL HSAFSSLGSL EGDAYVVSAK ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENTKDEEILD SAIRILVNLT VPVECLFSVD VMYRTEVGRH TIFELNKLLH TSKEAFTDPK STKSVVEYMK HILESDSKLS PKKCDQINNC LLLLRNILHI PESNANYLMP STSHNQLGGS HPVSMQNAIL WNLFIQSIDK LLLYLMTCPQ RAFWGVTMVQ LIALIYKDQH VSTLQKLLNL WFEASLSESS EDNESNTSPP KQGSCDSSPM LTSDPTSDSS DNGSAGSKNS NSEDRRQALR EETEATLQEV SRKGQEYQDS MLRVPADKVD SSEGASDVGN TDCEEVFSVN LEQQSSEIME TVDGEEAAHS DATVIDPSNN LETDRTKEIP TSTSETSDEI VTATITNKNE QPAEQDSSTS NLADAANFMP PPALPLKGSA PVSKNRCVNA DLKNTTKKSN QKSPHSGHVK LTMGNCGPQK RECPSSQSEL SDCGYGTQVE NQESISTSSN DDDSPQGKPQ HQKPPCSSKA RNKHRIVLTA IDKKELRRKK LVKRSKSSLI NMKGLVQHTP TDEDISNLLK EFTVDFLLKG YGYLVEDLYS QLLTNLKIPI DSSHFFWLVT YFLKFAAQLE LDMEHINTIL TFDVISYLTY EGVMLCEQLE LNSRQEGSDL KSYMRRMHLV VTAIREFLQA IETYKKVTHL SDEDRTRLRI LQVQISSTED LRNLFVLLLR RFNPSLHTKQ YLRDLVVTNH ILLLILDSVT KSNCNIHIKM IDHISQFATL EIMHYYGMLL DDFNNNGEFV NDCIFTMMHH IGGDLGQIGT LFQPVILKTF SRIWEADYEL CDDWSDLIEY VIHKFMNTPQ KSPLTLPSTS LTELTKEHNT ETAVCTWTQE DMDTLYWYYV QSKKNNDIVD KIVKLFSNNG NKQKSRISII QQLLQQDIIT LVEYDDLMKF EDAEYQRTLL TTPTSGTTES GIEIKETPQK GKPSDDVQIL RDLIIKENKQ QHLVWLQKLL LECCYIKLIL RNNPLRKDHQ NLTYIMEPVA YHCILKNNSI PVVQWNNEHS TMMLYQPFVL LLHKLGFQLP ADAGSVFARI PDFWTPEMMF NLAKKLGSLE KLSIKFDTHQ FDVINNMEMP NTSQSQYEAS TTTRNSFSSM SSLEVDLNDS DELAPIPEVD DILEKTSQAS EIFAMPNAKQ CNSIIRYTPE PTTLPTIPNW LQLVLRSKCN NANGSTSNVA AASASLANLA TNVCNDSDIW ITNNTKSNNQ TTTLPGNGAD SSAVATSIAI KVSVSSLAET KVPNIANTGS SSSTLTMAAA TSAILHPTTA ATTTLLACPS INQIIGLQHE TSNNNDCAKL PSNNKQKLTL SASFNSLTTT SLTTPTTTVT ATTLAIPFST TLLTPSTAAV TALVTPTSLV TITTMPNAAN TTESVPLATS ATSLAVSFKD YQQQLHYNSN KNNFNNQLQQ QLLHHEQQQQ QQQQDQQQQQ QQQQQQQQQQ QQQQQHHITY IIHSDDDDSA MKSLERNDSS ASSGFYTRSG SGNLEQELCA MVASAYEQEN ANSDSASVAS DLTRMYVSDE EPEYRVALYH // ID Q9BDH5_SHEEP Unreviewed; 109 AA. AC Q9BDH5; DT 01-JUN-2001, integrated into UniProtKB/TrEMBL. DT 01-JUN-2001, sequence version 1. DT 02-MAR-2010, entry version 16. DE SubName: Full=Timeless; DE Flags: Fragment; GN Name=Tim; OS Ovis aries (Sheep). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia; OC Pecora; Bovidae; Caprinae; Ovis. OX NCBI_TaxID=9940; RN [1] RP NUCLEOTIDE SEQUENCE. RA Messager S., Begbie K.M., Miller D.W., Barrett P., Hazlerigg D.G.; RT "Parallel developmental loss of mt(1) melatonin receptor and timeless RT mRNA expression in the rat anterior pituitary gland."; RL Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AY027884; AAK19026.1; -; mRNA. DR UniGene; Oar.819; -. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; FT NON_TER 1 1 FT NON_TER 109 109 SQ SEQUENCE 109 AA; 12781 MW; A27D8A3BA4B746ED CRC64; LQRDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKEPSFRHHF LQVLAYLQAY KEAFASEKVF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHV // ID Q9FLX0_ARATH Unreviewed; 1141 AA. AC Q9FLX0; DT 01-MAR-2001, integrated into UniProtKB/TrEMBL. DT 01-MAR-2001, sequence version 1. DT 03-SEP-2014, entry version 63. DE SubName: Full=Timeless family protein; GN Name=ATIM; OrderedLocusNames=At5g52910; OS Arabidopsis thaliana (Mouse-ear cress). OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; OC Spermatophyta; Magnoliophyta; eudicotyledons; Gunneridae; OC Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; OC Arabidopsis. OX NCBI_TaxID=3702; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=9628582; DOI=10.1093/dnares/5.1.41; RA Sato S., Kaneko T., Kotani H., Nakamura Y., Asamizu E., Miyajima N., RA Tabata S.; RT "Structural analysis of Arabidopsis thaliana chromosome 5. IV. RT Sequence features of the regions of 1,456,315 bp covered by nineteen RT physically assigned P1 and TAC clones."; RL DNA Res. 5:41-54(1998). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=cv. Columbia; RX PubMed=11130714; DOI=10.1038/35048507; RG Kazusa DNA Research Institute; RG Cold Spring Harbor and Washington University in St Louis Sequencing Consortium; RG European Union Arabidopsis Genome Sequencing Consortium; RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., RA Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., RA Nakazaki N., Naruo K., Okumura S., Shinpo S., Takeuchi C., Wada T., RA Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., RA Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., RA Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., RA Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., RA Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., RA Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., RA Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., RA Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., RA Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., RA Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., RA Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., RA Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., RA van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., RA Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., RA Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., RA Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., RA Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.; RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis RT thaliana."; RL Nature 408:823-826(2000). RN [3] RP NUCLEOTIDE SEQUENCE. RG TAIR; RA Swarbreck D., Lamesch P., Wilks C., Huala E.; RL Submitted (FEB-2011) to the EMBL/GenBank/DDBJ databases. RN [4] RP GENOME REANNOTATION. RC STRAIN=cv. Columbia; RG The Arabidopsis Information Resource (TAIR); RL Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP002688; AED96277.1; -; Genomic_DNA. DR EMBL; AB009055; BAB10439.1; -; Genomic_DNA. DR RefSeq; NP_200103.1; NM_124669.2. DR UniGene; At.29587; -. DR EnsemblPlants; AT5G52910.1; AT5G52910.1; AT5G52910. DR GeneID; 835368; -. DR KEGG; ath:AT5G52910; -. DR TAIR; AT5G52910; -. DR HOGENOM; HOG000084060; -. DR InParanoid; Q9FLX0; -. DR KO; K03155; -. DR OMA; HKQPKSD; -. DR PRO; PR:Q9FLX0; -. DR Genevestigator; Q9FLX0; -. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 4: Predicted; KW Complete proteome; Reference proteome. SQ SEQUENCE 1141 AA; 128902 MW; 334148C3A3D44252 CRC64; MDVEERISTK KKIDLEGLSV ICSDLGLPEE DEDRRRIGYS KSEYCLDNLK DLLRFLRRDD PESREVFKQV CAWNIVSKDL IPIIEHYQDE HNLVLNAVKV LVFLTMPIEP SSDDIPQQLE YLWGLKSAIT FSNIVAVIVS LLEAPLENLE LDVFNEEDWK LVQLVLTLFR NLLAIHDVSP IQKAGESTCY FLSLRDQFLE VLSRENVMDI VLVITQTIEG FNSLLRHDNL LLLEIYHYIL LGQDMELVAK APEKLDQGKQ ASVDSLKTLM KEEEVKRKLA RLNNMNQRHS QFGGTFTRVT MDGTKAVLKG IPSTTESTML KPQQGRGATE KIVWEHGPMS VTNDKSLCED IEKEHPSIQN SDIVTFFQVA QSITSFQFHK SSASSPAIET EETSELTTNQ KAGVNFSKSD ICAPIAATIN DRMFLLVISK WRCAFDGLKE TKDFKFLSAA SSLVKTMLCL LDLVIKLLPE DSKEAFTVRI LLYKLFYDQT DQGMCQFILN LVRSFDTHKQ PKSELGDLVE SIHIIVGLME NLQGRGTLRV SKKSRKARKK KPKGNKEATV HKLSENHPST SNEASTAKSI PMVDSTVSTE DGPMDVPPNK PEASNLETET DETQQMHSPK SNNVVDDLSS GSDDSSDGEE QTATDEVDFK VSTFISAFAS NSIIQNLCWL LKFYKSNPKQ TNHHVISILR RITEDLELAP MLYQLSLLIT FHKILDEQKV CPCKDYENIV TFLTDLVRNM LKKMKSQPLL FVEILFSKTR KECHYINAEY MLHELGHLRK QMGNQEKFSG TEEFGTSSDK GWAHRSLADA LGDDEADVVI SYDQGFQNED DDMVEDKSAG PSKRKRRLVL DGDMDIKIKD LYDRYKDDKN CSRLIAENLV PDGGISAAQV TNKLKQLGLE TRKRLRRGGT DHLDATSLAQ PSNTRKRVSS FSKEQETLIK ELYKKFKDEK RCCYLIASEL GSENTYTTAQ VSRKLKQLGL RLPRGKKSEA GMMLKDDHDD SSADESEDET LLAFKNRKSR KNQKNKQQTG SINEITPGGS EDNTERNETS LHEPTAGEEE DNDQSYITRE SRQSETDVHI SDNGPSTSLP EDPNLSSDNE LEDDELADWG DDSAAGGASL TQSPLSRRKL KMVLDKDDED D // ID Q9NAX2_DROME Unreviewed; 1384 AA. AC Q9NAX2; DT 01-OCT-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2000, sequence version 1. DT 26-JUN-2013, entry version 44. DE SubName: Full=TIM2 protein; GN Name=timeout; Synonyms=tim2; ORFNames=CG7855; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=10899011; DOI=10.1016/S0960-9822(00)00594-7; RA Benna C., Scannapieco P., Piccin A., Sandrelli F., Zordan M., RA Rosato E., Kyriacou C.P., Valle G., Costa R.; RT "A second timeless gene in Drosophila shares greater sequence RT similarity with mammalian tim."; RL Curr. Biol. 10:R512-R513(2000). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF279586; AAF82381.1; -; mRNA. DR PRIDE; Q9NAX2; -. DR FlyBase; FBgn0038118; timeout. DR InParanoid; Q9NAX2; -. DR Bgee; Q9NAX2; -. DR GO; GO:0000077; P:DNA damage checkpoint; IMP:FlyBase. DR GO; GO:0009649; P:entrainment of circadian clock; IMP:FlyBase. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1384 AA; 159264 MW; F13131A0FE3171C4 CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALLTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGGGA SRKKKQAATK SKPPAAPQPT EEELSSKWAE LATEVCSLLS TELEMPEDEQ PLPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MSNITTVESE DKENEKDQKQ DEYEDEDDDL DNEEYEEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL KAAVTILHRI AYGCKCAGML FQAKLFRIFQ QVFSVERDVH QEELRRLAIF VVRKFVEVAP TNPKIYAELL FYKGIREANE LESGYCDAYE AGTKGAWTEE QESELRFLFE ENQRNPETDK DVIDWILDNL VDKTRNRRTV LKKLKELGLL FKAPTKRSTK SAQSGKNVWQ PEEDDELRSL YDQHRIEPDC LERLVNEFAE RRSKQQIIKR MLQIHLIADK SEILPAKKGR GKDKPKKDVE MEGEGDEFDF AEEPMFEDQG YKKPKSKPKK VQKRQMVRTP LDVGTIRALI GQVDSEKYQS AIEWLQECLQ DASEDTEEAV EDDDGVPLLP LMENQKNAME DGDFQKVLVA LGMQPPISGM EAYWRIPIYL NSADLILRSK ILAGEEVDAE PEDEAADDED GEEAEESDEE EDFLEKHSRQ RKENIATQQQ RKLDSLMFNQ SDDETEQRAP PKAKDKPKAS EKKAKRKVKG KAKESKDCND DGTDKAELEK PNTDDLFNQL RAKRATKIKL SDMALNESTN AAQEADDDAF NFNSEDYRAR LLELEDEEQN SKDADENGGD KENITNKSLQ RARRVNVIDS DSDNDDDGAL PADKTNKRPR SDDDGDSGHM DANAEEDSDE EANFLARKKP AKVDGEPAKR RRLAIIDDDD EDDF // ID Q9NG27_DROME Unreviewed; 1384 AA. AC Q9NG27; DT 01-OCT-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2000, sequence version 1. DT 09-JUL-2014, entry version 46. DE SubName: Full=TIMEOUT; GN Name=timeout; ORFNames=CG7855; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE. RX PubMed=10903565; DOI=10.1038/77653; RA Gotter A.L., Manganaro T., Weaver D.R., Kolakowski L.F. Jr, RA Possidente B., Sriram S., MacLaughlin D.T., Reppert S.M.; RT "A time-less function for mouse timeless."; RL Nat. Neurosci. 3:755-756(2000). CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF268472; AAF73481.1; -; mRNA. DR STRING; 7227.FBpp0082180; -. DR PRIDE; Q9NG27; -. DR FlyBase; FBgn0038118; timeout. DR InParanoid; Q9NG27; -. DR PhylomeDB; Q9NG27; -. DR Bgee; Q9NG27; -. DR GO; GO:0000077; P:DNA damage checkpoint; IMP:FlyBase. DR GO; GO:0009649; P:entrainment of circadian clock; IMP:FlyBase. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1384 AA; 159378 MW; F12C0DE71F98276B CRC64; MSILLADIDA TCAALGYSDG QKYQAEPDAA EGLKHLIWIL RRDLDNHEYR RHLGRSKVLQ TDLVYMLPDY VHHEELSDLL IRLLVILTNP TLLLYREGAP KDNHGRKVFM ELIDILQGYK AAFAKDKVWS ALFEKLKQAL EIAFAIRSEE QNLLIERILV LVRNVLQVPA NPEAECRADN DASLHDQVIW ALHQTGMLDL VLFVISSPDE EQFHLHGLEI VCLLFREQSA ESLADASLQR SLSEKQRDQQ ELLAARRRER ARRQARPPPG RHSRFGGTYV IRNMKSVSDR DVICHQALER VSSIDFDREK QQQKRSHRHI QEEAQVTRRS AFTVRLCLRE YCIEVLRSAY NTLVRQVRRV LERNAGSSSH DDSYLLWAIR FFMEFNRLSG LQLQLVSESL SVQCFHWVLT RMQHDMDMIV SDKKQARLWA KRLHVALKTF RELLQSLLAL QKLKDDNNAR ALFDMLLNNV CYVLEYRETV LHLLMNYNEA HSTKVFLRDV VETANVFIKM MERFCQDSVV VQDKKRGRGA SRKKKQAATK SKPPAAPQPT EEELSSKWAE LATEVCSLLS TELEMPEDEQ PLPFDAASEK SIDDQREDCM IRINKLLRSE KLDQAIALLR AAREVWPENE VFGAISAAPE DELLLLREIF MSNITTVESE DKENEKDQKQ DEYEDEDDDL DNEEYEEQDN GLTEKTFKFD DFARRLLNPK IVRACTLVLS DWADIPTRSL KAAVTILHRI AYGCKCAGML FQAKLFRIFQ QVFSVERDVH QEELRRLAIF VVRKFVEVAP TNPKIYAELL FYKGIREANE LESGYCDAYE AGTKGAWTEE QESELRFLFE ENQRNPETDK DVIDWILDNL VDKTRNRRTV LKKLKELGLL FKAPTKRSTK SAQSGKNVWQ PEEDDELRSL YDQHRIEPDC LERLVNEFAE RRSKQQIIKR MLQIHLIADK SEILPAKKGR GKDKPKKDVE MEGEGDEFDF AEEPMFEDQG YKKPKSKPKK VQKRQMVRTP LDVGTIRALI GQVDSEKYQS AIEWLQECLQ DASEDTEEAV EDDDGVPLLP LMENQKNAME DGDFQKVLVA LGMQPPISGM EAYWRIPIYL NSADLILRSK ILAGEEVDAE PEDEAADDED GEEAEESDEE EDFLEKHSRQ RKENIATQQQ RKLDSLMFNQ SDDETEQRAP PKAKDKPKAS EKKAKRKVKG KAKESKDCND DGTDKAELEK PNTDDLFNQL RAKRATKIKL SDMALNESTN AAQEADDDAF NFNSEDYRAR LLELEDEEQN SKDADENGGD KENITNKSLQ RARRVNVIDS DSDNDDDGAL PADKTNKRPR SDDDGDSGHM DANAEEDSDE EANFLARKKP AKVDGEPAKR RRLAIIDDDD EDDF // ID Q9NJQ0_ANTPE Unreviewed; 1233 AA. AC Q9NJQ0; DT 01-OCT-2000, integrated into UniProtKB/TrEMBL. DT 01-OCT-2000, sequence version 1. DT 03-OCT-2012, entry version 16. DE SubName: Full=Timeless; GN Name=TIM; OS Antheraea pernyi (Chinese oak silk moth). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; OC Bombycoidea; Saturniidae; Saturniinae; Saturniini; Antheraea. OX NCBI_TaxID=7119; RN [1] RP NUCLEOTIDE SEQUENCE. RA Reppert S.M.; RT "Molecular Analysis of Silk Moth Timeless."; RL Submitted (FEB-1999) to the EMBL/GenBank/DDBJ databases. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF132032; AAF66996.1; -; mRNA. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; SQ SEQUENCE 1233 AA; 141049 MW; 933F9DD23C0F8F6C CRC64; MEWVLRSPQI HSTFSNLGFI HADGYHVNEN CNSALETILH NILTEDKYLR TFRRNISFGQ NIKKDFIPLL IHAKEDKTIE LLIKILVNLT IPIECLLCVE VISKNDFGRH TIFEINNLLS TTKAAFTDHR ATKVVIDFLK KNGNCEQKSE LSAEQCTNIS NSLLLLRNIL HIPEDHQNSN YNGSPHVVQN QILWNIFSQS IDKILIKLMT IPDATKWAVT MVQLIALLYK DQHVVTLHKL LNIWLEGSLS ESSEDNESNT SPPDRGSDDS SPILTSDPTS DSSDNGGSGK SNDEPNSVNN GWDSSSMNNA SENGNQVFHT ANEKGVHSVK KNLLKVGTTE ESMKIDEEKV DSCREVTNSE STSHDHSHGY TSTKKPNITE NSDCGYGTQI ENQESISTSS NEDDVPTKKP VHLKPHNPKQ RVNNKARSGI TPQERKRKKI VKRGKCNIIN VQGLTHKTPT DDDISNVLKE FTVDFLLKGY NSLVQTLHTQ ILTNLQLEID TSHFFWLVTY FLKFATQIEL DLELVCSVLS FDIISYLTAE GVNLCEQFEL AIKIDGNDLK PCMRRLHLVV TAIRELIQAI EIYKKFPHLC KEDQETLIKL QIKICETEDL RSLMVLLLRH YNPRYHSKQY LQDLIVTNHN LLTFLDKVMK LPDYRGSTNM VDHLRQFTSP EIMYQYGLLL ESFADNGEYV NDCIFTLMYH VGGELDSLIS LFQPKILKIF TFIWKSEFEI CDDWSDLVEY VINTFIKKPH TLQSVVELQQ DNESFDDDKL ILKQINATEL QSNQLKESWT EDELSSLSWN FMQCGTSLNV IEDIIKLFKE DDIIKSRECV IKELLNQNLI NKNEYEKFMK GDNDGNKAVP ISKETRDDEV RKLCEEIAKD GKSKFLDWVQ KALLDTCFAK ICMDKKSQDE LPPTNDCKLL DFELFKKKSV EFPPMSPVAY YSLRLNQSVP LVPWNCDQGS FCKDLRFLQL LHKLGFHMPV DSAKIFIRIP NFWTAEHLYE IAGKIAPIDN STLKFSVSDI SDYNWTKAKV HDHFMIPTDF GRDIVMNDTS DNSYQIHKHF SAMVNFTPMP GTSFNSDNNE VNEQSNSWLE VVMKSQEYKI TLSRLVEDDN DDDLMKLPVI EKDSITAMIT DMEPVAGPSK NSSAPLLMPT VMTTTQDVLP FNNNLAESEF YNNSICETAS VASDLTRMYV SDEDEKPDVI LRPELEINMD KRCSSPSEDT NVKRFRIDFS PDF // ID SWI1_SCHPO Reviewed; 971 AA. AC Q9UUM2; Q9Y7X0; DT 13-APR-2004, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-2000, sequence version 1. DT 11-JUN-2014, entry version 85. DE RecName: Full=Mating-type switching protein swi1; DE AltName: Full=Replication fork protection complex subunit swi1; GN Name=swi1; ORFNames=SPBC216.06c; OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; OC Schizosaccharomycetes; Schizosaccharomycetales; OC Schizosaccharomycetaceae; Schizosaccharomyces. OX NCBI_TaxID=284812; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RC STRAIN=972 / ATCC 24843; RA Schmidt H.; RL Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=972 / ATCC 24843; RX PubMed=11859360; DOI=10.1038/nature724; RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., RA Collins M., Connor R., Cronin A., Davis P., Feltwell T., Fraser A., RA Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., RA Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., RA James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., RA Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., RA Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., RA Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., RA Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., RA Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., RA Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., RA Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., RA Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., RA Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., RA Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., RA Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., RA Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., RA Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., RA Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., RA Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., RA Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., RA Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.; RT "The genome sequence of Schizosaccharomyces pombe."; RL Nature 415:871-880(2002). RN [3] RP FUNCTION, AND SUBCELLULAR LOCATION. RX PubMed=14560029; DOI=10.1128/MCB.23.21.7861-7874.2003; RA Noguchi E., Noguchi C., Du L.L., Russell P.; RT "Swi1 prevents replication fork collapse and controls checkpoint RT kinase Cds1."; RL Mol. Cell. Biol. 23:7861-7874(2003). RN [4] RP FUNCTION. RX PubMed=11030618; DOI=10.1016/S0092-8674(00)00063-5; RA Dalgaard J.Z., Klar A.J.; RT "swi1 and swi3 perform imprinting, pausing, and termination of DNA RT replication in S. pombe."; RL Cell 102:745-751(2000). RN [5] RP FUNCTION, INTERACTION WITH SWI3, AND SUBCELLULAR LOCATION. RX PubMed=15367656; DOI=10.1128/MCB.24.19.8342-8355.2004; RA Noguchi E., Noguchi C., McDonald W.H., Yates J.R. III, Russell P.; RT "Swi1 and swi3 are components of a replication fork protection complex RT in fission yeast."; RL Mol. Cell. Biol. 24:8342-8355(2004). RN [6] RP FUNCTION, AND INTERACTION WITH SWI3. RX PubMed=15509785; DOI=10.1128/MCB.24.22.9813-9822.2004; RA Lee B.-S., Grewal S.I.S., Klar A.J.S.; RT "Biochemical interactions between proteins and mat1 cis-acting RT sequences required for imprinting in fission yeast."; RL Mol. Cell. Biol. 24:9813-9822(2004). RN [7] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-528; SER-536 AND RP SER-970, AND IDENTIFICATION BY MASS SPECTROMETRY. RX PubMed=18257517; DOI=10.1021/pr7006335; RA Wilson-Grady J.T., Villen J., Gygi S.P.; RT "Phosphoproteome analysis of fission yeast."; RL J. Proteome Res. 7:1088-1097(2008). CC -!- FUNCTION: Forms a fork protection complex (FPC) with swi3. FPC CC coordinates leading and lagging strand synthesis and moves with CC the replication fork. It is required for programmed fork-pausing CC which is necessary for mating-type switching. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors. It is involved in termination at CC the mat1-proximal polar-terminator of replication (RTS1) and also CC required for activation of the Rad53-like checkpoint kinase cds1. CC -!- SUBUNIT: Fork protection complex (FPC) consisting of swi1 and swi3 CC interacts with mat1 cis-acting sequences and mat1-proximal polar- CC terminator of replication (RTS1). CC -!- INTERACTION: CC O14350:swi3; NbExp=5; IntAct=EBI-465942, EBI-465952; CC -!- SUBCELLULAR LOCATION: Nucleus. Note=Associated with chromatin CC during S phase. Nuclear accumulation requires swi3. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; Y19036; CAB44362.1; -; Genomic_DNA. DR EMBL; CU329671; CAB40166.1; -; Genomic_DNA. DR PIR; T39912; T39912. DR PIR; T43656; T43656. DR RefSeq; NP_595358.1; NM_001021265.2. DR BioGrid; 277251; 38. DR IntAct; Q9UUM2; 4. DR MINT; MINT-4715234; -. DR STRING; 4896.SPBC216.06c-1; -. DR MaxQB; Q9UUM2; -. DR EnsemblFungi; SPBC216.06c.1; SPBC216.06c.1:pep; SPBC216.06c. DR GeneID; 2540728; -. DR KEGG; spo:SPBC216.06c; -. DR PomBase; SPBC216.06c; -. DR eggNOG; NOG328380; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR PhylomeDB; Q9UUM2; -. DR NextBio; 20801850; -. DR GO; GO:0044732; C:mitotic spindle pole body; IDA:PomBase. DR GO; GO:0005634; C:nucleus; IDA:UniProtKB. DR GO; GO:0031298; C:replication fork protection complex; TAS:PomBase. DR GO; GO:0003682; F:chromatin binding; IDA:PomBase. DR GO; GO:0003677; F:DNA binding; IDA:PomBase. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0071515; P:genetic imprinting at mating-type locus; IMP:PomBase. DR GO; GO:0033314; P:mitotic DNA replication checkpoint; IGI:PomBase. DR GO; GO:0045950; P:negative regulation of mitotic recombination; IDA:PomBase. DR GO; GO:0043111; P:replication fork arrest; IDA:PomBase. DR GO; GO:0031297; P:replication fork processing; IMP:PomBase. DR GO; GO:0048478; P:replication fork protection; IDA:UniProtKB. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 1: Evidence at protein level; KW Cell cycle; Complete proteome; DNA damage; DNA replication inhibitor; KW Nucleus; Phosphoprotein; Reference proteome. FT CHAIN 1 971 Mating-type switching protein swi1. FT /FTId=PRO_0000072348. FT MOD_RES 528 528 Phosphoserine. FT MOD_RES 536 536 Phosphoserine. FT MOD_RES 970 970 Phosphoserine. FT CONFLICT 195 195 A -> R (in Ref. 1; CAB44362). SQ SEQUENCE 971 AA; 112628 MW; 77A0FB265C82C2BE CRC64; MELDEVIQGI VSAIGGFDYS DDEKVYVLGD EALACLKDLK RYLQVVDEKY KVWQIRSLLS SLQLVTNDIC PILSDWDKDI TNYRNWRIAL ACVELLVPLT WPLETEHETF RENVDVLYNL RQAQSNYKNS ILSYKKGSVL SAILAVLLKP LSTPAESRTL RDKGIIRIVL LLFRNILQID ELKTKNETII SFAKAHILDL IVTLVSNLDE FEHFDVYILE IVYNLIRGCK PSALFSDASL TNSQTELNSL LLKESTQNRY LKRNAHTRHN RFGTMLSVQT EDRRFTIASQ NIKTDGLDEL DSHKRFRKRG TRRKHFDDIN KSFFINTEAG TALRNFAVEF LEAGFNPLFQ SLLKDLERED PRVLPIHKMQ LLYVQSFFLE FMRFSSKPKK TEEIYSNDYS FGLAASVFDQ RALIMHNRLM VESFEMKQWS TFQASMLSMT QLLFTLRSMT LCSSEIYQRI ADNLLSNIFY QEEILLLVYS ALKHFKTQSF GYLDAITELT IVLLKELEKF SSAKQYLYVK KRRRNQKSVD SNVLESDEDE ESSLINANAA VEDRLFDFGR YESRYCDNGC IDSFVLFLQC YQDLDSKQIH RAISFFYRIF VKQKCHVYLY RLDFLRVLDK MFNDHVYFST TNSARQDFEQ FFVYYMRKLS DALKDVPALF IELPFPKLTD TFYYLEYGKS PLFSIHGSRK GPLYETVPGL SHLEKVAAVV ACLINENKSD LLDELKVQLN CLISERKLIT LADENKYINE GGNDGERMGK NLKGDTDSFN TALLKDGKFR LLLELCGFEE SDNNIDVQAL WKLPNSVIID ELVEHAMLLR RFTDDPPTFE GTKPEDLLVR KQRGNVRLPS SSEGETSDEE IEFEADDPIT FANRREALNK ITDRKRKKMK TNETIIDHTT RKKKENHLRS AKYIVDSDDD SETDIAFFQS EAALREKNAQ KASALFKRID DLEMEGKLQE IEQLSENSSS D // ID TIM_DROHY Reviewed; 676 AA. AC O44431; DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot. DT 01-JUN-1998, sequence version 1. DT 03-APR-2013, entry version 43. DE RecName: Full=Protein timeless; DE Flags: Fragment; GN Name=tim; OS Drosophila hydei (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7224; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=9504927; RA Ousley A., Zafarullah K., Chen Y., Emerson M., Hickman L., Sehgal A.; RT "Conserved regions of the timeless (tim) clock gene in Drosophila RT analyzed through phylogenetic and functional studies."; RL Genetics 148:815-825(1998). CC -!- FUNCTION: Required for the production of circadian rhythms. The CC biological cycle depends on the rhythmic formation and nuclear CC localization of the TIM-PER complex. Light induces the degradation CC of TIM, which promotes elimination of PER. Nuclear activity of the CC heterodimer coordinatively regulates PER and TIM transcription CC through a negative feedback loop. Behaves as a negative element in CC circadian transcriptional loop. Does not appear to bind DNA, CC suggesting indirect transcriptional inhibition (By similarity). CC -!- SUBUNIT: Forms a heterodimer with period (PER); the complex then CC translocates into the nucleus (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm, perinuclear region. CC Note=Nuclear at specific periods of the day. First accumulates in CC the perinuclear region about one hour before translocation into CC the nucleus. Interaction with per is required for nuclear CC localization (By similarity). CC -!- DOMAIN: Contains a 32 AA domain highly conserved between species. CC Deletion of this domain leads to long-period phenotype and CC arrhythmia (By similarity). CC -!- PTM: Phosphorylated with a circadian rhythmicity (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF038579; AAB92669.1; -; Genomic_DNA. DR FlyBase; FBgn0023352; Dhyd\tim. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Biological rhythms; Cytoplasm; Nucleus; Phosphoprotein; Repeat. FT CHAIN <1 >676 Protein timeless. FT /FTId=PRO_0000072536. FT REGION 77 108 Necessary for normal circadian rhythm (By FT similarity). FT MOTIF 388 398 Nuclear localization signal (Potential). FT NON_TER 1 1 FT NON_TER 676 676 SQ SEQUENCE 676 AA; 76023 MW; 73EBBD1E098DDBF6 CRC64; MLLRNILHIP ETHAHFLMPV LQSSGGHQVS MQNTILWNLF IQSIDKLLLY LMTCPQRALW GVTMVQLIAM IYKDQHVNTL QKLLNLWFEA SLSESSEDNE SNTSPPKKGS GDSSPMLTSD PTSDSSDNGS NGGGSSGKKE GCDERRQALR EGTEATLQEV SRKGHDYQNA MARVTADKPD ISEVASDSFE VPCSPQQHLN TEEAMDDIDY EEQVQEYEQE AAAVSSEPLN LSQPANNVNY TTNAVYASTT ATETQTTSSL CAMTSLCYEP FKPPAPLPTR RNTLSEMLSD NYTSHSHVSA VKLGQKSSHA GQLQLTKGKC CPQKRECPSS QSELSDCGYA TQVENPESIS TSSNDDDGPQ GKPQHQKPPC NTKPRNKQRT LMSPQDKKEL RRKKLVKRSK SSLINMKGLV QHTPTNYDIS NLLKEFTVDF LLKGYNYLVE ELLKQLLTSA KVLIDTSHFF WLVTFFLKLA AQLELDMEHI DSILTYDVLS YLTYEGVSLC EQLELNAQQE GSDLQPYLRR MHLVVTAIRE FLQTIETYNK VSHLSEDDRL RLHQLQLQIG ATTDLRCLFV LLLRRFNPRI HSKQYLQDLV VTNHILMLIL DSAAKLEGGQ TIGLSEHISQ FATLEVMHYY GILLEDFDNN GEFVNDCIFT MMHHIGGDLG QIGVLFQPII LKTYSR // ID TIM_DROME Reviewed; 1398 AA. AC P49021; A4V040; B7Z007; B7Z008; C9QPB7; M9MRE9; O44380; Q1WWF5; AC Q59E16; Q8I037; Q95U67; Q9VQR6; Q9VQR7; DT 01-FEB-1996, integrated into UniProtKB/Swiss-Prot. DT 14-MAY-2014, sequence version 3. DT 03-SEP-2014, entry version 124. DE RecName: Full=Protein timeless; GN Name=tim; ORFNames=CG3234; OS Drosophila melanogaster (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila; Sophophora. OX NCBI_TaxID=7227; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM R). RX PubMed=7481771; DOI=10.1126/science.270.5237.805; RA Myers M.P., Wager-Smith K., Wesley C.S., Young M.W., Sehgal A.; RT "Positional cloning and sequence analysis of the Drosophila clock RT gene, timeless."; RL Science 270:805-808(1995). RN [2] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=9365248; DOI=10.1093/nar/25.23.4710; RA Myers M.P., Rothenfluh A., Chang M., Young M.W.; RT "Comparison of chromosomal DNA composing timeless in Drosophila RT melanogaster and D. virilis suggests a new conserved structure for the RT TIMELESS protein."; RL Nucleic Acids Res. 25:4710-4714(1997). RN [3] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=Berkeley; RX PubMed=10731132; DOI=10.1126/science.287.5461.2185; RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D., RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F., RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N., RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., RA Brandon R.C., Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., RA Wan K.H., Doyle C., Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., RA Abril J.F., Agbayani A., An H.-J., Andrews-Pfannkoch C., Baldwin D., RA Ballew R.M., Basu A., Baxendale J., Bayraktaroglu L., Beasley E.M., RA Beeson K.Y., Benos P.V., Berman B.P., Bhandari D., Bolshakov S., RA Borkova D., Botchan M.R., Bouck J., Brokstein P., Brottier P., RA Burtis K.C., Busam D.A., Butler H., Cadieu E., Center A., Chandra I., RA Cherry J.M., Cawley S., Dahlke C., Davenport L.B., Davies P., RA de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I., Dietz S.M., RA Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C., Dunn P., RA Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S., Fleischmann W., RA Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M., Glasser K., RA Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M., RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., RA Hostin D., Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., RA Jalali M., Kalush F., Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., RA Kimmel B.E., Kodira C.D., Kraft C.L., Kravitz S., Kulp D., Lai Z., RA Lasko P., Lei Y., Levitsky A.A., Li J.H., Li Z., Liang Y., Lin X., RA Liu X., Mattei B., McIntosh T.C., McLeod M.P., McPherson D., RA Merkulov G., Milshina N.V., Mobarry C., Morris J., Moshrefi A., RA Mount S.M., Moy M., Murphy B., Murphy L., Muzny D.M., Nelson D.L., RA Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R., Pacleb J.M., RA Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V., Reese M.G., RA Reinert K., Remington K., Saunders R.D.C., Scheeler F., Shen H., RA Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J., RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., RA Svirskas R., Tector C., Turner R., Venter E., Wang A.H., Wang X., RA Wang Z.-Y., Wassarman D.A., Weinstock G.M., Weissenbach J., RA Williams S.M., Woodage T., Worley K.C., Wu D., Yang S., Yao Q.A., RA Ye J., Yeh R.-F., Zaveri J.S., Zhan M., Zhang G., Zhao Q., Zheng L., RA Zheng X.H., Zhong F.N., Zhong W., Zhou X., Zhu S.C., Zhu X., RA Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M., Venter J.C.; RT "The genome sequence of Drosophila melanogaster."; RL Science 287:2185-2195(2000). RN [4] RP GENOME REANNOTATION, AND ALTERNATIVE SPLICING. RC STRAIN=Berkeley; RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083; RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S., RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E., RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P., RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A., RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., RA Stapleton M., Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., RA Lewis S.E.; RT "Annotation of the Drosophila melanogaster euchromatic genome: a RT systematic review."; RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002). RN [5] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-30, AND ALTERNATIVE INITIATION. RC STRAIN=Canton-S, CO-TG14, CO-TG20, PER+, PER01, and PERS; RX PubMed=9016581; DOI=10.1093/nar/25.3.455; RA Rosato E., Trevisan A., Sandrelli F., Zordan M., Kyriacou C.P., RA Costa R.; RT "Conceptual translation of timeless reveals alternative initiating RT methionines in Drosophila."; RL Nucleic Acids Res. 25:455-458(1997). RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 34-1398 (ISOFORM O), AND RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1115-1398 (ISOFORMS B/L/R). RC STRAIN=Berkeley; TISSUE=Head; RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080; RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., RA George R.A., Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., RA Rubin G.M., Celniker S.E.; RT "A Drosophila full-length cDNA resource."; RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002). RN [7] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM N), AND NUCLEOTIDE RP SEQUENCE [LARGE SCALE MRNA] OF 907-1398 (ISOFORMS B/L/R). RC STRAIN=Berkeley; RA Stapleton M., Booth B., Carlson J., Chavez C., Frise E., George R., RA Pacleb J., Park S., Wan K., Yu C., Celniker S.; RL Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases. RN [8] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 220-284, FUNCTION, TISSUE RP SPECIFICITY, AND DISRUPTION PHENOTYPE. RX PubMed=9504927; RA Ousley A., Zafarullah K., Chen Y., Emerson M., Hickman L., Sehgal A.; RT "Conserved regions of the timeless (tim) clock gene in Drosophila RT analyzed through phylogenetic and functional studies."; RL Genetics 148:815-825(1998). RN [9] RP FUNCTION, AND DISRUPTION PHENOTYPE. RX PubMed=8128247; DOI=10.1126/science.8128247; RA Vosshall L.B., Price J.L., Sehgal A., Saez L., Young M.W.; RT "Block in nuclear localization of period protein by a second clock RT mutation, timeless."; RL Science 263:1606-1609(1994). RN [10] RP FUNCTION. RX PubMed=7481772; DOI=10.1126/science.270.5237.808; RA Sehgal A., Rothenfluh-Hilfiker A., Hunter-Ensor M., Chen Y., RA Myers M.P., Young M.W.; RT "Rhythmic expression of timeless: a basis for promoting circadian RT cycles in period gene autoregulation."; RL Science 270:808-810(1995). RN [11] RP FUNCTION, AND INTERACTION WITH PER. RX PubMed=7481773; DOI=10.1126/science.270.5237.811; RA Gekakis N., Saez L., Delahaye-Brown A.M., Myers M.P., Sehgal A., RA Young M.W., Weitz C.J.; RT "Isolation of timeless by PER protein interaction: defective RT interaction between timeless protein and long-period mutant PERL."; RL Science 270:811-815(1995). RN [12] RP FUNCTION, TISSUE SPECIFICITY, AND SUBCELLULAR LOCATION. RX PubMed=8625406; DOI=10.1016/S0092-8674(00)81046-6; RA Hunter-Ensor M., Ousley A., Sehgal A.; RT "Regulation of the Drosophila protein timeless suggests a mechanism RT for resetting the circadian clock by light."; RL Cell 84:677-685(1996). CC -!- FUNCTION: Required for the production of circadian rhythms. The CC biological cycle depends on the rhythmic formation and nuclear CC localization of the TIM-PER complex. Light induces the degradation CC of TIM, which promotes elimination of PER. Nuclear activity of the CC heterodimer coordinatively regulates PER and TIM transcription CC through a negative feedback loop. Behaves as a negative element in CC circadian transcriptional loop. Does not appear to bind DNA, CC suggesting indirect transcriptional inhibition. CC -!- SUBUNIT: Forms a heterodimer with period (PER); the complex then CC translocates into the nucleus. CC -!- SUBCELLULAR LOCATION: Nucleus. Cytoplasm, perinuclear region. CC Note=Nuclear at specific periods of the day. First accumulates in CC the perinuclear region about one hour before translocation into CC the nucleus. Interaction with per is required for nuclear CC localization. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing, Alternative initiation; Named isoforms=7; CC Name=B; Synonyms=P, Q; CC IsoId=P49021-4; Sequence=Displayed; CC Name=R; CC IsoId=P49021-2; Sequence=VSP_004457; CC Note=No experimental confirmation available; CC Name=O; CC IsoId=P49021-3; Sequence=VSP_007693, VSP_007694; CC Note=No experimental confirmation available; CC Name=N; CC IsoId=P49021-5; Sequence=VSP_054859, VSP_007693, VSP_007694; CC Note=No experimental confirmation available; CC Name=S; CC IsoId=P49021-6; Sequence=VSP_004457, VSP_054860, VSP_054861; CC Note=No experimental confirmation available; CC Name=M; CC IsoId=P49021-7; Sequence=VSP_054860, VSP_054861; CC Note=No experimental confirmation available; CC Name=L; CC IsoId=P49021-8; Sequence=VSP_054859; CC Note=No experimental confirmation available; CC -!- TISSUE SPECIFICITY: Expressed in head, photoreceptors, lateral CC neurons and glial cells in the lamina and medulla of the optic CC lobes. Expression follows a light-dark cycle, levels show a CC significant decrease at the end of the night and then remain low CC throughout the light period (at protein level). CC -!- PTM: Phosphorylated with a circadian rhythmicity. CC -!- DISRUPTION PHENOTYPE: Mutant flies show loss of both behavioral CC circadian rhythms and molecular oscillations of per RNA and CC protein. CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=AAC46920.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; CC Sequence=AAL13507.1; Type=Erroneous initiation; Note=Translation N-terminally extended; CC Sequence=AAN71179.1; Type=Erroneous initiation; Note=Translation N-terminally extended; CC Sequence=AAN71179.1; Type=Miscellaneous discrepancy; Note=Intron retention; CC Sequence=ACX54883.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; U37018; AAC46920.1; ALT_INIT; mRNA. DR EMBL; AF032401; AAB94890.1; -; Genomic_DNA. DR EMBL; AF032400; AAB94890.1; JOINED; Genomic_DNA. DR EMBL; AE014134; AAF51097.1; -; Genomic_DNA. DR EMBL; AE014134; AAF51098.4; -; Genomic_DNA. DR EMBL; AE014134; AAN10371.3; -; Genomic_DNA. DR EMBL; AE014134; AAN10372.3; -; Genomic_DNA. DR EMBL; AE014134; AAX52649.2; -; Genomic_DNA. DR EMBL; AE014134; ABC65862.2; -; Genomic_DNA. DR EMBL; AE014134; ACL82987.2; -; Genomic_DNA. DR EMBL; AE014134; ACL82988.2; -; Genomic_DNA. DR EMBL; AE014134; ADV36936.2; -; Genomic_DNA. DR EMBL; Y09930; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Y09931; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Y09932; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Y09933; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Y09934; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; Y09935; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; AY058278; AAL13507.1; ALT_INIT; mRNA. DR EMBL; BT001424; AAN71179.1; ALT_SEQ; mRNA. DR EMBL; BT024951; ABE01181.1; -; mRNA. DR EMBL; BT099999; ACX54883.1; ALT_INIT; mRNA. DR EMBL; AF038501; AAB94929.1; -; Genomic_DNA. DR PIR; A57655; A57655. DR RefSeq; NP_001014463.2; NM_001014463.3. [P49021-6] DR RefSeq; NP_001033872.2; NM_001038783.3. [P49021-7] DR RefSeq; NP_001137780.2; NM_001144308.3. [P49021-2] DR RefSeq; NP_001137781.2; NM_001144309.3. [P49021-3] DR RefSeq; NP_001188686.2; NM_001201757.1. [P49021-5] DR RefSeq; NP_001188687.2; NM_001201758.2. [P49021-4] DR RefSeq; NP_722912.3; NM_164540.4. [P49021-4] DR RefSeq; NP_722913.3; NM_164541.5. [P49021-8] DR RefSeq; NP_722914.3; NM_164542.4. [P49021-4] DR UniGene; Dm.2663; -. DR BioGrid; 59781; 7. DR DIP; DIP-29425N; -. DR MINT; MINT-344208; -. DR EnsemblMetazoa; FBtr0333253; FBpp0305451; FBgn0014396. [P49021-7] DR EnsemblMetazoa; FBtr0333254; FBpp0305452; FBgn0014396. [P49021-5] DR EnsemblMetazoa; FBtr0333255; FBpp0305453; FBgn0014396. [P49021-3] DR EnsemblMetazoa; FBtr0333258; FBpp0305456; FBgn0014396. [P49021-2] DR EnsemblMetazoa; FBtr0333259; FBpp0305457; FBgn0014396. [P49021-6] DR GeneID; 33571; -. DR KEGG; dme:Dmel_CG3234; -. DR UCSC; CG3234-RA; d. melanogaster. [P49021-4] DR CTD; 107698; -. DR FlyBase; FBgn0014396; tim. DR eggNOG; NOG257888; -. DR GeneTree; ENSGT00390000015124; -. DR InParanoid; P49021; -. DR KO; K12074; -. DR OrthoDB; EOG7SXW2F; -. DR ChiTaRS; ARHGEF5; drosophila. DR GenomeRNAi; 33571; -. DR NextBio; 784249; -. DR Bgee; P49021; -. DR GO; GO:0005737; C:cytoplasm; IDA:FlyBase. DR GO; GO:0005634; C:nucleus; IDA:FlyBase. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0043234; C:protein complex; IPI:FlyBase. DR GO; GO:0005515; F:protein binding; IPI:UniProtKB. DR GO; GO:0046982; F:protein heterodimerization activity; IPI:FlyBase. DR GO; GO:0008134; F:transcription factor binding; IPI:FlyBase. DR GO; GO:0071482; P:cellular response to light stimulus; IMP:FlyBase. DR GO; GO:0048512; P:circadian behavior; IMP:FlyBase. DR GO; GO:0007623; P:circadian rhythm; NAS:FlyBase. DR GO; GO:0060086; P:circadian temperature homeostasis; IMP:FlyBase. DR GO; GO:0007620; P:copulation; IMP:FlyBase. DR GO; GO:0008062; P:eclosion rhythm; NAS:FlyBase. DR GO; GO:0009649; P:entrainment of circadian clock; TAS:FlyBase. DR GO; GO:0045475; P:locomotor rhythm; IGI:FlyBase. DR GO; GO:0007617; P:mating behavior; IMP:FlyBase. DR GO; GO:0046957; P:negative phototaxis; IMP:FlyBase. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:FlyBase. DR GO; GO:2000678; P:negative regulation of transcription regulatory region DNA binding; IDA:FlyBase. DR GO; GO:0009648; P:photoperiodism; IMP:FlyBase. DR GO; GO:0006606; P:protein import into nucleus; NAS:FlyBase. DR GO; GO:0042749; P:regulation of circadian sleep/wake cycle; IMP:FlyBase. DR GO; GO:0045187; P:regulation of circadian sleep/wake cycle, sleep; IMP:FlyBase. DR GO; GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase. DR GO; GO:0007622; P:rhythmic behavior; TAS:FlyBase. DR GO; GO:0030431; P:sleep; NAS:FlyBase. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 1: Evidence at protein level; KW Alternative initiation; Alternative splicing; Biological rhythms; KW Complete proteome; Cytoplasm; Nucleus; Phosphoprotein; KW Reference proteome; Repeat. FT CHAIN 1 1398 Protein timeless. FT /FTId=PRO_0000022532. FT REGION 237 268 Necessary for normal circadian rhythm. FT MOTIF 550 560 Nuclear localization signal (Potential). FT COMPBIAS 360 389 Asp/Glu-rich (acidic). FT COMPBIAS 432 437 Poly-Pro. FT VAR_SEQ 237 268 Missing (in isoform R and isoform S). FT /FTId=VSP_004457. FT VAR_SEQ 613 613 Missing (in isoform L and isoform N). FT /FTId=VSP_054859. FT VAR_SEQ 891 891 C -> W (in isoform N and isoform O). FT /FTId=VSP_007693. FT VAR_SEQ 892 1398 Missing (in isoform N and isoform O). FT /FTId=VSP_007694. FT VAR_SEQ 1114 1131 LNLKFDASELEDATASSP -> RELKSTTEKNNPFVIPQR FT (in isoform S and isoform M). FT /FTId=VSP_054860. FT VAR_SEQ 1132 1398 Missing (in isoform S and isoform M). FT /FTId=VSP_054861. FT CONFLICT 1233 1233 I -> V (in Ref. 2; AAB94890). SQ SEQUENCE 1398 AA; 156382 MW; E7974EDCF6F94A88 CRC64; MDWLLATPQL YSAFSSLGCL EGDTYVVNPN ALAILEEINY KLTYEDQTLR TFRRAIGFGQ NVRSDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD VMYRTDVGRH TIFELNKLLY TSKEAFTEAR STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAHCVMP MMQSMPHGIS MQNTILWNLF IQSIDKLLLY LMTCPQRAFW GVTMVQLIAL IYKDQHVSTL QKLLSLWFEA SLSESSEDNE SNTSPPKQGS GDSSPMLTSD PTSDSSDNGS NGRGMGGGMR EGTAATLQEV SRKGQEYQNA MARVPADKPD GSEEASDMTG NDSEQPGSPE QSQPAGESMD DGDYEDQRHR QLNEHGEEDE DEDEVEEEEY LQLGPASEPL NLTQQPADKV NNTTNPTSSA PQGCLGNEPF KPPPPLPVRA STSAHAQMQK FNESSYASHV SAVKLGQKSP HAGQLQLTKG KCCPQKRECP SSQSELSDCG YGTQVENQES ISTSSNDDDG PQGKPQHQKP PCNTKPRNKP RTIMSPMDKK ELRRKKLVKR SKSSLINMKG LVQHTPTDDD ISNLLKEFTV DFLLKGYSYL VEELHMQLLS NAKVPIDTSH FFWLVTYFLK FAAQLELDME HIDTILTYDV LSYLTYEGVS LCEQLELNAR QEGSDLKPYL RRMHLVVTAI REFLQAIDTY NKVTHLNEDD KAHLRQLQLQ ISEMSDLRCL FVLLLRRFNP SIHSKQYLQD LVVTNHILLL ILDSSAKLGG CQTIRLSEHI TQFATLEVMH YYGILLEDFN NNGEFVNDCI FTMMHHIGGD LGQIGVLFQP IILKTYSRIW EADYELCDDW SDLIEYVIHK FMNTPPKSPL TIPTTSLTEM TKEHNQEHTV CSWSQEEMDT LYWYYVQSKK NNDIVGKIVK LFSNNGNKLK TRISIIQQLL QQDIITLLEY DDLMKFEDAE YQRTLLTTPT SATTESGIEI KECAYGKPSD DVQILLDLII KENKAQHLLW LQRILIECCF VKLTLRSGLK VPEGDHIMEP VAYHCICKQK SIPVVQWNNE QSTTMLYQPF VLLLHKLGIQ LPADAGSIFA RIPDYWTPET MYGLAKKLGP LDKLNLKFDA SELEDATASS PSRYHHTGPR NSLSSVSSLD VDLGDTEELA LIPEVDAAVE KAHAMASTPS PSEIFAVPKT KHCNSIIRYT PDPTPPVPNW LQLVMRSKCN HRTGPSGDPS DCIGSSSTTV DDEGFGKSIS AATSQAASTS MSTVNPTTTL SLNMLNTFMG SHNENSSSSG CGGTVSSLSM VALMSTGAAG GGGNTSGLEM DVDASMKSSF ERLEVNGSHF SRANNLDQEY SAMVASVYEK EKELNSDNVS LASDLTRMYV SDEDDRLERT EIRVPHYH // ID TIM_DROVI Reviewed; 1343 AA. AC O17482; O44430; O44785; DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot. DT 01-JAN-1998, sequence version 1. DT 13-NOV-2013, entry version 56. DE RecName: Full=Protein timeless; GN Name=tim; OS Drosophila virilis (Fruit fly). OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; OC Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; OC Ephydroidea; Drosophilidae; Drosophila. OX NCBI_TaxID=7244; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RX PubMed=9365248; DOI=10.1093/nar/25.23.4710; RA Myers M.P., Rothenfluh A., Chang M., Young M.W.; RT "Comparison of chromosomal DNA composing timeless in Drosophila RT melanogaster and D. virilis suggests a new conserved structure for the RT TIMELESS protein."; RL Nucleic Acids Res. 25:4710-4714(1997). RN [2] RP NUCLEOTIDE SEQUENCE OF 1-1194 AND 1196-1343. RX PubMed=9504927; RA Ousley A., Zafarullah K., Chen Y., Emerson M., Hickman L., Sehgal A.; RT "Conserved regions of the timeless (tim) clock gene in Drosophila RT analyzed through phylogenetic and functional studies."; RL Genetics 148:815-825(1998). CC -!- FUNCTION: Required for the production of circadian rhythms. The CC biological cycle depends on the rhythmic formation and nuclear CC localization of the TIM-PER complex. Light induces the degradation CC of TIM, which promotes elimination of PER. Nuclear activity of the CC heterodimer coordinatively regulates PER and TIM transcription CC through a negative feedback loop. Behaves as a negative element in CC circadian transcriptional loop. Does not appear to bind DNA, CC suggesting indirect transcriptional inhibition (By similarity). CC -!- SUBUNIT: Forms a heterodimer with period (PER); the complex then CC translocates into the nucleus (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm, CC perinuclear region (By similarity). Note=Nuclear at specific CC periods of the day. First accumulates in the perinuclear region CC about one hour before translocation into the nucleus. Interaction CC with per is required for nuclear localization (By similarity). CC -!- PTM: Phosphorylated with a circadian rhythmicity (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF032403; AAB94891.1; -; Genomic_DNA. DR EMBL; AF032402; AAB94891.1; JOINED; Genomic_DNA. DR EMBL; AF038502; AAB94930.1; -; Genomic_DNA. DR EMBL; AF040096; AAB94942.1; -; mRNA. DR FlyBase; FBgn0022834; Dvir\tim. DR eggNOG; NOG257888; -. DR InParanoid; O17482; -. DR OrthoDB; EOG7SXW2F; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell. DR GO; GO:0048511; P:rhythmic process; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 2: Evidence at transcript level; KW Biological rhythms; Cytoplasm; Nucleus; Phosphoprotein; Repeat. FT CHAIN 1 1343 Protein timeless. FT /FTId=PRO_0000072537. FT REGION 238 270 Necessary for normal circadian rhythm (By FT similarity). FT MOTIF 517 527 Nuclear localization signal (Potential). FT COMPBIAS 161 164 Poly-Leu. FT COMPBIAS 1135 1141 Poly-Ala. FT COMPBIAS 1249 1252 Poly-Ser. FT CONFLICT 851 851 Q -> H (in Ref. 2; AAB94930). FT CONFLICT 1180 1180 T -> S (in Ref. 2; AAB94930). FT CONFLICT 1223 1223 S -> A (in Ref. 2; AAB94942). SQ SEQUENCE 1343 AA; 150944 MW; 3FC2F286AC5355F5 CRC64; MDWLLATPQL QSVFSSLGSL VGGTYVVSPN ALAILEEINH KLTYEDQTLR TFRRAIGFGQ NVRVDLIPLL ENAKDDAVLE SVIRILVNLT VPVECLFSVD LMYRTEVGRH TIFELNKLLY NSKEAFTDPK STKSVVEYMK HILESDPKLS PHKCDQINNC LLLLRNILHI PETHAHFLMP RLQPGSGHQV SMQNTILWNL FIQSIDKLLL YLMTCPQRSL WGVTMVQLIA LIYKDQHVST LQKLLNLWFE ASLSESSDDN ESNTTPPKQA SGDSSPMLTS DPTSDSSDNG SGGKKESCEE RRQALREGTD ATLHEVSRKG HEYQNAMASS NAANYILEGP CSAQQPWSDC EMQEYKQMTA VISEPLNLSQ PADNVNYTTN ANYARTTSTD ILTKTTSLKH EGFKPPAPRR NTLSAILSDN YAPLSFISAV KLGQKSPHAG QLQLIKGKCC PQKRECPSSQ SEHSDCGYGT QMENPESIST SSNDDDGPQG KPQHQKPPCS SKHRSKQRIF AVPQDTKDLR RKKLVKRSKS SLINMKGLVL HTPNDDDISN LLKEFTVDFL LKGYNYLVEE LHSQLLSNAK MPIDTSHFFW LVTFFLKFAA QLELDMEHID TILTFDVLSF LTYEGVSLCE QLELNARQEG ADLRPYLRRM HLVVTAIREF LQAIEAYNKV THLSEDDRYR LRQLQLQISA TTDLRCLFVL LLRRFNPSIH SKQYLQDLVV TNHILLLILD NAAKLEGGQT IGLSEHISQF ATLEVMHYYG ILLEDFSNNG EYVNDCIFTM MHHIGGDLDQ VGVLYQPIIL KAYSRIWEAD YDICDDWSDL IEYVIHKFLN TPPKSPMAIP TASLTELTKE QNQEHTACPW SQEDMDSLCW YFVQSKRQND VIGNIAKLFS NNGNKIKTRI SIIQQLLQQD IITLLEYDDL MKFEDAEYQR TLLATPTSLT TDSGIELKES AYGKPSDDVQ VLLDLIRKEN KSQHLVWLQK LLLECCYVKM MIKCGSCQTD VEPIMEPVVY HCMFKQKPIP VVQWNNEQSS TMLYQPFMLL LHKLGIQLPA DAGLIFARIP DFWTPETMYG LAKKLGPLDK LTLKFDPRDL EDAPPSRHHT GARNSLSSIS SLEADFGDSE GLALIPEVDP AVEKAAAAAS AIPNNEIFAL PRVKHCNSII RYTPDPTPPV PSWLQLVMRT KCSKRRSPAT DASDCTSTST MIADDEIKSY ASMAQASHTK LNSGYPTSTL VCMNKLSNCS FAAPPNENSS SSGCGGTASS MSMPNMPDGN SDALMKTSFE RLAVTGARYL RPSNTDQDYS ALVASVYENE FANSDNVSVA SDLTRMYVSD EDEKHELQLQ QVE // ID TIM_HUMAN Reviewed; 1208 AA. AC Q9UNS1; B2ZAV0; O94802; Q86VM1; Q8IWH3; DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot. DT 18-MAY-2010, sequence version 2. DT 03-SEP-2014, entry version 117. DE RecName: Full=Protein timeless homolog; DE Short=hTIM; GN Name=TIMELESS; Synonyms=TIM, TIM1, TIMELESS1; OS Homo sapiens (Human). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; OC Catarrhini; Hominidae; Homo. OX NCBI_TaxID=9606; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, AND RP VARIANT LEU-455. RC TISSUE=Brain; RX PubMed=9891984; DOI=10.1016/S0014-5793(98)01597-X; RA Koike N., Hida A., Numano R., Hirose M., Sakaki Y., Tei H.; RT "Identification of the mammalian homologues of the Drosophila timeless RT gene, Timeless1."; RL FEBS Lett. 441:427-431(1998). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, TISSUE RP SPECIFICITY, AND VARIANTS LEU-455 AND GLN-831. RC TISSUE=Placenta; RX PubMed=9856465; DOI=10.1016/S0896-6273(00)80627-3; RA Sangoram A.M., Saez L., Antoch M.P., Gekakis N., Staknis D., RA Whiteley A., Fruechte E.M., Vitaterna M.H., Shimomura K., King D.P., RA Young M.W., Weitz C.J., Takahashi J.S.; RT "Mammalian circadian autoregulatory loop: a timeless ortholog and RT mPer1 interact and negatively regulate CLOCK-ARTNL/BMAL1-induced RT transcription."; RL Neuron 21:1101-1113(1998). RN [3] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS SER-129; LEU-455; RP SER-471; GLN-831; VAL-870; HIS-922; TRP-924; THR-1017 AND LEU-1018. RG NIEHS SNPs program; RL Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases. RN [4] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RX PubMed=16541075; DOI=10.1038/nature04569; RA Scherer S.E., Muzny D.M., Buhay C.J., Chen R., Cree A., Ding Y., RA Dugan-Rocha S., Gill R., Gunaratne P., Harris R.A., Hawes A.C., RA Hernandez J., Hodgson A.V., Hume J., Jackson A., Khan Z.M., RA Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L., RA Milosavljevic A., Miner G.R., Montgomery K.T., Morgan M.B., RA Nazareth L.V., Scott G., Sodergren E., Song X.-Z., Steffen D., RA Lovering R.C., Wheeler D.A., Worley K.C., Yuan Y., Zhang Z., RA Adams C.Q., Ansari-Lari M.A., Ayele M., Brown M.J., Chen G., Chen Z., RA Clerc-Blankenburg K.P., Davis C., Delgado O., Dinh H.H., Draper H., RA Gonzalez-Garay M.L., Havlak P., Jackson L.R., Jacob L.S., Kelly S.H., RA Li L., Li Z., Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., RA Okwuonu G.O., Pasternak S., Perez L.M., Plopper F.J.H., Santibanez J., RA Shen H., Tabor P.E., Verduzco D., Waldron L., Wang Q., Williams G.A., RA Zhang J., Zhou J., Allen C.C., Amin A.G., Anyalebechi V., Bailey M., RA Barbaria J.A., Bimage K.E., Bryant N.P., Burch P.E., Burkett C.E., RA Burrell K.L., Calderon E., Cardenas V., Carter K., Casias K., RA Cavazos I., Cavazos S.R., Ceasar H., Chacko J., Chan S.N., Chavez D., RA Christopoulos C., Chu J., Cockrell R., Cox C.D., Dang M., RA Dathorne S.R., David R., Davis C.M., Davy-Carroll L., Deshazo D.R., RA Donlin J.E., D'Souza L., Eaves K.A., Egan A., Emery-Cohen A.J., RA Escotto M., Flagg N., Forbes L.D., Gabisi A.M., Garza M., Hamilton C., RA Henderson N., Hernandez O., Hines S., Hogues M.E., Huang M., RA Idlebird D.G., Johnson R., Jolivet A., Jones S., Kagan R., King L.M., RA Leal B., Lebow H., Lee S., LeVan J.M., Lewis L.C., London P., RA Lorensuhewa L.M., Loulseged H., Lovett D.A., Lucier A., Lucier R.L., RA Ma J., Madu R.C., Mapua P., Martindale A.D., Martinez E., Massey E., RA Mawhiney S., Meador M.G., Mendez S., Mercado C., Mercado I.C., RA Merritt C.E., Miner Z.L., Minja E., Mitchell T., Mohabbat F., RA Mohabbat K., Montgomery B., Moore N., Morris S., Munidasa M., RA Ngo R.N., Nguyen N.B., Nickerson E., Nwaokelemeh O.O., Nwokenkwo S., RA Obregon M., Oguh M., Oragunye N., Oviedo R.J., Parish B.J., RA Parker D.N., Parrish J., Parks K.L., Paul H.A., Payton B.A., Perez A., RA Perrin W., Pickens A., Primus E.L., Pu L.-L., Puazo M., Quiles M.M., RA Quiroz J.B., Rabata D., Reeves K., Ruiz S.J., Shao H., Sisson I., RA Sonaike T., Sorelle R.P., Sutton A.E., Svatek A.F., Svetz L.A., RA Tamerisa K.S., Taylor T.R., Teague B., Thomas N., Thorn R.D., RA Trejos Z.Y., Trevino B.K., Ukegbu O.N., Urban J.B., Vasquez L.I., RA Vera V.A., Villasana D.M., Wang L., Ward-Moore S., Warren J.T., RA Wei X., White F., Williamson A.L., Wleczyk R., Wooden H.S., RA Wooden S.H., Yen J., Yoon L., Yoon V., Zorrilla S.E., Nelson D., RA Kucherlapati R., Weinstock G., Gibbs R.A.; RT "The finished DNA sequence of human chromosome 12."; RL Nature 440:346-351(2006). RN [5] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), AND RP VARIANTS GLN-831 AND LEU-1018. RC TISSUE=Duodenum, and Skin; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [6] RP INTERACTION WITH ATR; ATRIP; CHEK1 AND CRY2, AND INDUCTION. RX PubMed=15798197; DOI=10.1128/MCB.25.8.3109-3116.2005; RA Uensal-Kacmaz K., Mullen T.E., Kaufmann W.K., Sancar A.; RT "Coupling of human circadian and cell cycles by the timeless RT protein."; RL Mol. Cell. Biol. 25:3109-3116(2005). RN [7] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1173, AND IDENTIFICATION RP BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Cervix carcinoma; RX PubMed=17081983; DOI=10.1016/j.cell.2006.09.026; RA Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., RA Mann M.; RT "Global, in vivo, and site-specific phosphorylation dynamics in RT signaling networks."; RL Cell 127:635-648(2006). RN [8] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1173, AND IDENTIFICATION RP BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Cervix carcinoma; RX PubMed=16964243; DOI=10.1038/nbt1240; RA Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.; RT "A probability-based approach for high-throughput protein RT phosphorylation analysis and site localization."; RL Nat. Biotechnol. 24:1285-1292(2006). RN [9] RP INTERACTION WITH TIPIN. RX PubMed=17116885; DOI=10.1073/pnas.0609251103; RA Chou D.M., Elledge S.J.; RT "Tipin and Timeless form a mutually protective complex required for RT genotoxic stress resistance and checkpoint function."; RL Proc. Natl. Acad. Sci. U.S.A. 103:18143-18147(2006). RN [10] RP INTERACTION WITH TIPIN. RX PubMed=17102137; DOI=10.1074/jbc.M605596200; RA Yoshizawa-Sugata N., Masai H.; RT "Human Tim/Timeless-interacting protein, Tipin, is required for RT efficient progression of S phase and DNA replication checkpoint."; RL J. Biol. Chem. 282:2729-2740(2007). RN [11] RP SUBCELLULAR LOCATION, INTERACTION WITH CLSPN, AND FUNCTION. RX PubMed=17141802; DOI=10.1016/j.jmb.2006.10.097; RA Gotter A.L., Suppa C., Emanuel B.S.; RT "Mammalian TIMELESS and Tipin are evolutionarily conserved replication RT fork-associated factors."; RL J. Mol. Biol. 366:36-52(2007). RN [12] RP INTERACTION WITH TIPIN, AND FUNCTION. RX PubMed=17296725; DOI=10.1128/MCB.02190-06; RA Uensal-Kacmaz K., Chastain P.D., Qu P.-P., Minoo P., RA Cordeiro-Stone M., Sancar A., Kaufmann W.K.; RT "The human Tim/Tipin complex coordinates an Intra-S checkpoint RT response to UV that slows replication fork displacement."; RL Mol. Cell. Biol. 27:3131-3142(2007). RN [13] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Cervix carcinoma; RX PubMed=18669648; DOI=10.1073/pnas.0805139105; RA Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E., RA Elledge S.J., Gygi S.P.; RT "A quantitative atlas of mitotic phosphorylation."; RL Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). RN [14] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=19413330; DOI=10.1021/ac9004309; RA Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., RA Mohammed S.; RT "Lys-N and trypsin cover complementary parts of the phosphoproteome in RT a refined SCX-based approach."; RL Anal. Chem. 81:4493-4501(2009). RN [15] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1149 AND SER-1173, AND RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Leukemic T-cell; RX PubMed=19690332; DOI=10.1126/scisignal.2000007; RA Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., RA Rodionov V., Han D.K.; RT "Quantitative phosphoproteomic analysis of T cell receptor signaling RT reveals system-wide modulation of protein-protein interactions."; RL Sci. Signal. 2:RA46-RA46(2009). RN [16] RP REVIEW. RX PubMed=20139726; RA McFarlane R.J., Mian S., Dalgaard J.Z.; RT "The many facets of the Tim-Tipin protein families' roles in RT chromosome biology."; RL Cell Cycle 9:700-705(2010). RN [17] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1149 AND SER-1173, AND RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC TISSUE=Cervix carcinoma; RX PubMed=20068231; DOI=10.1126/scisignal.2000475; RA Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., RA Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., RA Mann M.; RT "Quantitative phosphoproteomics reveals widespread full RT phosphorylation site occupancy during mitosis."; RL Sci. Signal. 3:RA3-RA3(2010). RN [18] RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21269460; DOI=10.1186/1752-0509-5-17; RA Burkard T.R., Planyavsky M., Kaupe I., Breitwieser F.P., RA Buerckstuemmer T., Bennett K.L., Superti-Furga G., Colinge J.; RT "Initial characterization of the human central proteome."; RL BMC Syst. Biol. 5:17-17(2011). RN [19] RP REVIEW. RX PubMed=21670590; RA Diaz-Martinez L.A., Clarke D.J.; RT "Timeless makes some time for itself."; RL Cell Cycle 10:2254-2254(2011). RN [20] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1149 AND SER-1173, AND RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RX PubMed=21406692; DOI=10.1126/scisignal.2001570; RA Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., RA Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., RA Blagoev B.; RT "System-wide temporal characterization of the proteome and RT phosphoproteome of human embryonic stem cell differentiation."; RL Sci. Signal. 4:RS3-RS3(2011). RN [21] RP FUNCTION. RX PubMed=23418588; DOI=10.1371/journal.pone.0056623; RA Engelen E., Janssens R.C., Yagita K., Smits V.A., van der Horst G.T., RA Tamanini F.; RT "Mammalian TIMELESS is involved in period determination and DNA RT damage-dependent phase advancing of the circadian clock."; RL PLoS ONE 8:E56623-E56623(2013). RN [22] RP VARIANTS [LARGE SCALE ANALYSIS] ASP-429 AND GLU-1008. RX PubMed=16959974; DOI=10.1126/science.1133427; RA Sjoeblom T., Jones S., Wood L.D., Parsons D.W., Lin J., Barber T.D., RA Mandelker D., Leary R.J., Ptak J., Silliman N., Szabo S., RA Buckhaults P., Farrell C., Meeh P., Markowitz S.D., Willis J., RA Dawson D., Willson J.K.V., Gazdar A.F., Hartigan J., Wu L., Liu C., RA Parmigiani G., Park B.H., Bachman K.E., Papadopoulos N., RA Vogelstein B., Kinzler K.W., Velculescu V.E.; RT "The consensus coding sequences of human breast and colorectal RT cancers."; RL Science 314:268-274(2006). CC -!- FUNCTION: Plays an important role in the control of DNA CC replication, maintenance of replication fork stability, CC maintenance of genome stability throughout normal DNA replication CC and in the regulation of the circadian clock. Involved in the CC determination of period length and in the DNA damage-dependent CC phase advancing of the circadian clock. Negatively regulates CC CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of CC PER1 possibly via translocation of PER1 into the nucleus. Forms a CC complex with TIPIN and this complex regulates DNA replication CC processes under both normal and stress conditions, stabilizes CC replication forks and influences both CHEK1 phosphorylation and CC the intra-S phase checkpoint in response to genotoxic stress. CC Timeless promotes TIPIN nuclear localization. Involved in cell CC survival after DNA damage or replication stress. May be CC specifically required for the ATR-CHEK1 pathway in the replication CC checkpoint induced by hydroxyurea or ultraviolet light. May also CC play an important role in epithelial cell morphogenesis and CC formation of branching tubules. CC -!- SUBUNIT: Homodimer or homomultimer. Component of the circadian CC core oscillator, which includes the CRY proteins, CLOCK or NPAS2, CC ARTNL/BMAL1 or ARTNL2/BMAL2, CSKN1D and/or CSNK1E, TIMELESS, and CC the PER proteins. Interacts directly with PER1, PER2 and PER3; the CC interaction with PER2 is via its second PAS domain. Interacts with CC CRY1, CRY2, CHEK1, ATR and ATRIP. Interacts with CLSPN and TIPIN. CC -!- INTERACTION: CC O14757:CHEK1; NbExp=2; IntAct=EBI-2212315, EBI-974488; CC -!- SUBCELLULAR LOCATION: Nucleus. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing; Named isoforms=2; CC Name=1; CC IsoId=Q9UNS1-1; Sequence=Displayed; CC Name=2; CC IsoId=Q9UNS1-2; Sequence=VSP_051693; CC -!- TISSUE SPECIFICITY: Expressed in all tissues examined including CC brain, heart, lung, liver, skeletal muscle, kidney, placenta, CC pancreas, spleen, thymus and testis. Highest levels of expression CC in placenta, pancreas, thymus and testis. CC -!- INDUCTION: Regulated by the cell cycle. High levels in S, G(2) and CC M phases, with highest level in S phase. Low expression in G(0) CC and G(1) phases. CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=AAH39842.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; CC -!- WEB RESOURCE: Name=NIEHS-SNPs; CC URL="http://egp.gs.washington.edu/data/timeless/"; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB015597; BAA36499.1; -; mRNA. DR EMBL; AF098162; AAC80011.1; -; mRNA. DR EMBL; EU627094; ACD11488.1; -; Genomic_DNA. DR EMBL; AC024884; -; NOT_ANNOTATED_CDS; Genomic_DNA. DR EMBL; BC039842; AAH39842.1; ALT_SEQ; mRNA. DR EMBL; BC050557; AAH50557.1; -; mRNA. DR CCDS; CCDS8918.1; -. [Q9UNS1-1] DR RefSeq; NP_003911.2; NM_003920.3. [Q9UNS1-1] DR UniGene; Hs.118631; -. DR ProteinModelPortal; Q9UNS1; -. DR BioGrid; 114428; 22. DR IntAct; Q9UNS1; 7. DR STRING; 9606.ENSP00000229201; -. DR PhosphoSite; Q9UNS1; -. DR DMDM; 296452931; -. DR MaxQB; Q9UNS1; -. DR PaxDb; Q9UNS1; -. DR PRIDE; Q9UNS1; -. DR Ensembl; ENST00000229201; ENSP00000229201; ENSG00000111602. [Q9UNS1-2] DR Ensembl; ENST00000553532; ENSP00000450607; ENSG00000111602. [Q9UNS1-1] DR GeneID; 8914; -. DR KEGG; hsa:8914; -. DR UCSC; uc001slf.2; human. [Q9UNS1-1] DR CTD; 8914; -. DR GeneCards; GC12M056810; -. DR H-InvDB; HIX0010725; -. DR HGNC; HGNC:11813; TIMELESS. DR HPA; HPA060655; -. DR MIM; 603887; gene. DR neXtProt; NX_Q9UNS1; -. DR PharmGKB; PA36520; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000133002; -. DR HOVERGEN; HBG079258; -. DR InParanoid; Q9UNS1; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR PhylomeDB; Q9UNS1; -. DR TreeFam; TF312802; -. DR GenomeRNAi; 8914; -. DR NextBio; 33532; -. DR PRO; PR:Q9UNS1; -. DR ArrayExpress; Q9UNS1; -. DR Bgee; Q9UNS1; -. DR CleanEx; HS_TIMELESS; -. DR Genevestigator; Q9UNS1; -. DR GO; GO:0000790; C:nuclear chromatin; IDA:HGNC. DR GO; GO:0005634; C:nucleus; IC:UniProtKB. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IEA:Ensembl. DR GO; GO:0044770; P:cell cycle phase transition; IMP:BHF-UCL. DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW. DR GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB. DR GO; GO:0009582; P:detection of abiotic stimulus; TAS:ProtInc. DR GO; GO:0009790; P:embryo development; IEA:Ensembl. DR GO; GO:0030324; P:lung development; IEA:Ensembl. DR GO; GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0002009; P:morphogenesis of an epithelium; ISS:UniProtKB. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Ensembl. DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IDA:UniProtKB. DR GO; GO:0009628; P:response to abiotic stimulus; TAS:ProtInc. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 1: Evidence at protein level; KW Alternative splicing; Biological rhythms; Cell cycle; Cell division; KW Complete proteome; Developmental protein; DNA damage; Mitosis; KW Nucleus; Phosphoprotein; Polymorphism; Reference proteome; KW Transcription; Transcription regulation. FT CHAIN 1 1208 Protein timeless homolog. FT /FTId=PRO_0000072538. FT REGION 1 309 Required for homodimerization and for FT interaction with CRY1 and CHEK1 (By FT similarity). FT REGION 1082 1208 Required for nuclear localization (By FT similarity). FT COMPBIAS 661 688 Glu-rich. FT MOD_RES 1149 1149 Phosphoserine. FT MOD_RES 1173 1173 Phosphoserine. FT VAR_SEQ 177 177 Missing (in isoform 2). FT /FTId=VSP_051693. FT VARIANT 129 129 A -> S (in dbSNP:rs72478986). FT /FTId=VAR_047879. FT VARIANT 429 429 A -> D (in a breast cancer sample; FT somatic mutation). FT /FTId=VAR_036435. FT VARIANT 455 455 I -> L (in dbSNP:rs774027). FT /FTId=VAR_021483. FT VARIANT 471 471 N -> S (in dbSNP:rs72478993). FT /FTId=VAR_047880. FT VARIANT 831 831 R -> Q (in dbSNP:rs774047). FT /FTId=VAR_021484. FT VARIANT 870 870 M -> V (in dbSNP:rs61733875). FT /FTId=VAR_047881. FT VARIANT 922 922 R -> H (in dbSNP:rs72478999). FT /FTId=VAR_047882. FT VARIANT 924 924 R -> W (in dbSNP:rs72479000). FT /FTId=VAR_047883. FT VARIANT 1008 1008 Q -> E (in a breast cancer sample; FT somatic mutation). FT /FTId=VAR_036436. FT VARIANT 1017 1017 I -> T (in dbSNP:rs61376834). FT /FTId=VAR_047884. FT VARIANT 1018 1018 P -> L (in dbSNP:rs2291739). FT /FTId=VAR_021485. SQ SEQUENCE 1208 AA; 138658 MW; 16C6C07DDC6D2701 CRC64; MDLHMMNCEL LATCSALGYL EGDTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHHQDKPLFD AVIRLMVNLT QPALLCFGNL PKEPSFRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEERQE EDNLLIERIL LLVRNILHVP ADLDQEKKID DDASAHDQLL WAIHLSGLDD LLLFLASSSA EEQWSLHVLE IVSLMFRDQN PEQLAGVGQG RLAQERSADF AELEVLRQRE MAEKKTRALQ RGNRHSRFGG SYIVQGLKSI GERDLIFHKG LHNLRNYSSD LGKQPKKVPK RRQAARELSI QRRSALNVRL FLRDFCSEFL ENCYNRLMGS VKDHLLREKA QQHDETYYMW ALAFFMAFNR AASFRPGLVS ETLSVRTFHF IEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDISPDEA VRESSRIIKN NIFYVMEYRE LFLALFRKFD ERCQPRSFLR DLVETTHLFL KMLERFCRSR GNLVVQNKQK KRRKKKKKVL DQAIVSGNVP SSPEEVEAVW PALAEQLQCC AQNSELSMDS VVPFDAASEV PVEEQRAEAM VRIQDCLLAG QAPQALTLLR SAREVWPEGD VFGSQDISPE EEIQLLKQIL SAPLPRQQGP EERGAEEEEE EEEEEEEELQ VVQVSEKEFN FLDYLKRFAC STVVRAYVLL LRSYQQNSAH TNHCIVKMLH RLAHDLKMEA LLFQLSVFCL FNRLLSDPAA GAYKELVTFA KYILGKFFAL AAVNQKAFVE LLFWKNTAVV REMTEGYGSL DDRSSSRRAP TWSPEEEAHL RELYLANKDV EGQDVVEAIL AHLNTVPRTR KQIIHHLVQM GLADSVKDFQ RKGTHIVLWT GDQELELQRL FEEFRDSDDV LGHIMKNITA KRSRARIVDK LLALGLVAER RELYKKRQKK LASSILPNGA ESLKDFCQED LEEEENLPEE DSEEEEEGGS EAEQVQGSLV LSNENLGQSL HQEGFSIPLL WLQNCLIRAA DDREEDGCSQ AVPLVPLTEE NEEAMENEQF QQLLRKLGVR PPASGQETFW RIPAKLSPTQ LRRAAASLSQ PEEEQKLQPE LQPKVPGEQG SDEEHCKEHR AQALRALLLA HKKKAGLASP EEEDAVGKEP LKAAPKKRQL LDSDEEQEED EGRNRAPELG APGIQKKKRY QIEDDEDD // ID TIM_MOUSE Reviewed; 1197 AA. AC Q9R1X4; Q63ZX9; Q6P204; Q6PDL4; Q7TPV8; Q8R0Q2; Q9R268; Q9Z0E7; DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot. DT 15-MAR-2005, sequence version 3. DT 03-SEP-2014, entry version 106. DE RecName: Full=Protein timeless homolog; DE Short=mTim; GN Name=Timeless; Synonyms=Tim1, Timeless1; OS Mus musculus (Mouse). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Mus; Mus. OX NCBI_TaxID=10090; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, AND RP DEVELOPMENTAL STAGE. RC STRAIN=BALB/c; TISSUE=Brain; RX PubMed=9891984; DOI=10.1016/S0014-5793(98)01597-X; RA Koike N., Hida A., Numano R., Hirose M., Sakaki Y., Tei H.; RT "Identification of the mammalian homologues of the Drosophila timeless RT gene, Timeless1."; RL FEBS Lett. 441:427-431(1998). RN [2] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 6), TISSUE SPECIFICITY, RP DEVELOPMENTAL STAGE, FUNCTION, AND INTERACTION WITH PER1 AND PER2. RC TISSUE=Embryo; RX PubMed=9856465; DOI=10.1016/S0896-6273(00)80627-3; RA Sangoram A.M., Saez L., Antoch M.P., Gekakis N., Staknis D., RA Whiteley A., Fruechte E.M., Vitaterna M.H., Shimomura K., King D.P., RA Young M.W., Weitz C.J., Takahashi J.S.; RT "Mammalian circadian autoregulatory loop: a timeless ortholog and RT mPer1 interact and negatively regulate CLOCK-ARTNL/BMAL1-induced RT transcription."; RL Neuron 21:1101-1113(1998). RN [3] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), AND TISSUE SPECIFICITY. RC STRAIN=C57BL/6; TISSUE=Brain; RX PubMed=9856466; DOI=10.1016/S0896-6273(00)80628-5; RA Zylka M.J., Shearman L.P., Levine J.D., Jin X., Weaver D.R., RA Reppert S.M.; RT "Molecular analysis of mammalian timeless."; RL Neuron 21:1115-1122(1998). RN [4] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION, TISSUE RP SPECIFICITY, INDUCTION, AND INTERACTION WITH PER1. RC STRAIN=BALB/c; TISSUE=Brain; RX PubMed=10231394; DOI=10.1046/j.1365-2443.1999.00238.x; RA Takumi T., Nagamine Y., Miyake S., Matsubara C., Taguchi K., RA Takekida S., Sakakida Y., Nishikawa K., Kishimoto T., Niwa S., RA Okumura K., Okamura H.; RT "A mammalian ortholog of Drosophila timeless, highly expressed in SCN RT and retina, forms a complex with mPER1."; RL Genes Cells 4:67-75(1999). RN [5] RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4), FUNCTION, TISSUE SPECIFICITY, RP AND DEVELOPMENTAL STAGE. RC TISSUE=Heart, and Kidney; RX PubMed=10963667; DOI=10.1073/pnas.97.18.10038; RA Li Z., Stuart R.O., Qiao J., Pavlova A., Bush K.T., Pohl M., RA Sakurai H., Nigam S.K.; RT "A role for Timeless in epithelial morphogenesis during kidney RT development."; RL Proc. Natl. Acad. Sci. U.S.A. 97:10038-10043(2000). RN [6] RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 5). RC STRAIN=C57BL/6, C57BL/6J, and FVB/N; RC TISSUE=Brain, Egg, Olfactory epithelium, and Salivary gland; RX PubMed=15489334; DOI=10.1101/gr.2596504; RG The MGC Project Team; RT "The status, quality, and expansion of the NIH full-length cDNA RT project: the Mammalian Gene Collection (MGC)."; RL Genome Res. 14:2121-2127(2004). RN [7] RP INTERACTION WITH CRY1 AND CRY2, FUNCTION, SUBCELLULAR LOCATION, TISSUE RP SPECIFICITY, AND INDUCTION. RX PubMed=10428031; DOI=10.1016/S0092-8674(00)81014-4; RA Kume K., Zylka M.J., Sriram S., Shearman L.P., Weaver D.R., Jin X., RA Maywood E.S., Hastings M.H., Reppert S.M.; RT "mCRY1 and mCRY2 are essential components of the negative limb of the RT circadian clock feedback loop."; RL Cell 98:193-205(1999). RN [8] RP INTERACTION WITH TIPIN, DEVELOPMENTAL STAGE, SUBUNIT, AND FUNCTION. RX PubMed=12875843; DOI=10.1016/S0022-2836(03)00633-8; RA Gotter A.L.; RT "Tipin, a novel timeless-interacting protein, is developmentally co- RT expressed with timeless and disrupts its self-association."; RL J. Mol. Biol. 331:167-176(2003). RN [9] RP INTERACTION WITH PER1; PER2 AND PER3, AND INDUCTION. RX PubMed=14564007; DOI=10.1126/science.1086593; RA Barnes J.W., Tischkau S.A., Barnes J.A., Mitchell J.W., Burgoon P.W., RA Hickok J.R., Gillette M.U.; RT "Requirement of mammalian Timeless for circadian rhythmicity."; RL Science 302:439-442(2003). RN [10] RP ERRATUM. RA Barnes J.W., Tischkau S.A., Barnes J.A., Mitchell J.W., Burgoon P.W., RA Hickok J.R., Gillette M.U.; RL Science 302:1153-1153(2003). RN [11] RP FUNCTION, SUBUNIT, INDUCTION, SUBCELLULAR LOCATION, TISSUE RP SPECIFICITY, AND INTERACTION WITH CRY1 AND CHEK1. RX PubMed=23418588; DOI=10.1371/journal.pone.0056623; RA Engelen E., Janssens R.C., Yagita K., Smits V.A., van der Horst G.T., RA Tamanini F.; RT "Mammalian TIMELESS is involved in period determination and DNA RT damage-dependent phase advancing of the circadian clock."; RL PLoS ONE 8:E56623-E56623(2013). RN [12] RP INTERACTION WITH CRY1, AND SUBCELLULAR LOCATION. RX PubMed=24489120; DOI=10.1093/nar/gku094; RA Kang T.H., Leem S.H.; RT "Modulation of ATR-mediated DNA damage checkpoint response by RT cryptochrome 1."; RL Nucleic Acids Res. 42:4427-4434(2014). CC -!- FUNCTION: Plays an important role in the control of DNA CC replication, maintenance of replication fork stability, CC maintenance of genome stability throughout normal DNA replication CC and in the regulation of the circadian clock. Involved in the CC determination of period length and in the DNA damage-dependent CC phase advancing of the circadian clock. Negatively regulates CC CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of CC PER1 possibly via translocation of PER1 into the nucleus. Forms a CC complex with TIPIN and this complex regulates DNA replication CC processes under both normal and stress conditions, stabilizes CC replication forks and influences both CHEK1 phosphorylation and CC the intra-S phase checkpoint in response to genotoxic stress. CC Timeless promotes TIPIN nuclear localization. Involved in cell CC survival after DNA damage or replication stress. May be CC specifically required for the ATR-CHEK1 pathway in the replication CC checkpoint induced by hydroxyurea or ultraviolet light. May also CC play an important role in epithelial cell morphogenesis and CC formation of branching tubules. CC -!- SUBUNIT: Homodimer or homomultimer. Component of the circadian CC core oscillator, which includes the CRY proteins, CLOCK or NPAS2, CC ARTNL/BMAL1 or ARTNL2/BMAL2, CSKN1D and/or CSNK1E, TIMELESS, and CC the PER proteins. Interacts directly with PER1, PER2 and PER3; the CC interaction with PER2 is via its second PAS domain. Interacts with CC CRY1, CRY2, CHEK1, ATR and ATRIP. Interacts with CLSPN and TIPIN. CC -!- INTERACTION: CC O35973:Per1; NbExp=3; IntAct=EBI-1793117, EBI-1266764; CC -!- SUBCELLULAR LOCATION: Nucleus. CC -!- ALTERNATIVE PRODUCTS: CC Event=Alternative splicing; Named isoforms=6; CC Name=1; CC IsoId=Q9R1X4-1; Sequence=Displayed; CC Name=2; CC IsoId=Q9R1X4-2; Sequence=VSP_051695; CC Note=No experimental confirmation available; CC Name=3; CC IsoId=Q9R1X4-3; Sequence=VSP_051695, VSP_051696; CC Note=No experimental confirmation available; CC Name=4; Synonyms=TIM-s; CC IsoId=Q9R1X4-4; Sequence=VSP_051694, VSP_051695; CC Name=5; CC IsoId=Q9R1X4-5; Sequence=VSP_051694; CC Note=No experimental confirmation available; CC Name=6; CC IsoId=Q9R1X4-6; Sequence=VSP_051697; CC -!- TISSUE SPECIFICITY: Predominantly and robustly expressed in CC proliferative organs (spleen, thymus, intestine and testis) CC compared to those more differentiated such as kidney and liver (at CC protein level). Expressed in all tissues examined including brain, CC heart, lung, liver, skeletal muscle, kidney, placenta, pancreas, CC spleen, thymus and testis. Strongly expressed in the CC suprachiasmatic nucleus (SCN) and pars tuberalis, moderately in CC the cingulate cortex, pyrimidal cell layer of the piriform cortex, CC periventricular part of the caudate putamen, and granular layer of CC the cerebellum, and weakly in the cerebral cortex, gyrus dentatus, CC hippocampus and thalamic nuclei. In embryonic kidney, expression CC is highest in regions of active ureteric bud cell branching. CC -!- DEVELOPMENTAL STAGE: Expression is highest in whole embryos at E11 CC and gradually decreases as embryonic development progresses. At CC E7.5, expressed in germ cell layers. At E14.5, expressed at CC highest levels in thymus, liver, gastrointestinal tract, lung and CC the rapidly proliferating ventricular zone of the brain. CC -!- INDUCTION: In retina, expression exhibits a circadian rhythm in CC the presence of light/dark cycles. In the suprachiasmatic nucleus CC (SCN), isoform 1 exhibited 24 hours oscillation, isoform 4 is CC constitutively expressed. Shows a circadian expression pattern in CC the intestine with peaks at ZT4 and ZT8. CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=AAH52884.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; CC Sequence=AAH64788.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB015598; BAA36500.1; -; mRNA. DR EMBL; AF098161; AAC80010.1; -; mRNA. DR EMBL; AF071506; AAC79687.1; -; mRNA. DR EMBL; AB019001; BAA76390.2; -; mRNA. DR EMBL; AF126480; AAD24467.1; -; mRNA. DR EMBL; BC026526; AAH26526.1; -; mRNA. DR EMBL; BC052884; AAH52884.1; ALT_SEQ; mRNA. DR EMBL; BC058641; AAH58641.1; -; mRNA. DR EMBL; BC064788; AAH64788.1; ALT_SEQ; mRNA. DR EMBL; BC082770; AAH82770.1; -; mRNA. DR CCDS; CCDS24266.1; -. [Q9R1X4-1] DR CCDS; CCDS48724.1; -. [Q9R1X4-6] DR CCDS; CCDS48725.1; -. [Q9R1X4-2] DR PIR; T13956; T13956. DR RefSeq; NP_001129554.1; NM_001136082.2. [Q9R1X4-2] DR RefSeq; NP_001157552.1; NM_001164080.1. [Q9R1X4-6] DR RefSeq; NP_001157553.1; NM_001164081.1. [Q9R1X4-1] DR RefSeq; NP_035719.1; NM_011589.2. [Q9R1X4-1] DR RefSeq; XP_006513646.1; XM_006513583.1. [Q9R1X4-1] DR UniGene; Mm.6458; -. DR ProteinModelPortal; Q9R1X4; -. DR BioGrid; 204198; 14. DR IntAct; Q9R1X4; 5. DR PhosphoSite; Q9R1X4; -. DR MaxQB; Q9R1X4; -. DR PaxDb; Q9R1X4; -. DR PRIDE; Q9R1X4; -. DR Ensembl; ENSMUST00000055539; ENSMUSP00000058021; ENSMUSG00000039994. [Q9R1X4-1] DR Ensembl; ENSMUST00000105242; ENSMUSP00000100876; ENSMUSG00000039994. [Q9R1X4-2] DR Ensembl; ENSMUST00000105244; ENSMUSP00000100878; ENSMUSG00000039994. [Q9R1X4-6] DR Ensembl; ENSMUST00000105245; ENSMUSP00000100879; ENSMUSG00000039994. [Q9R1X4-1] DR GeneID; 21853; -. DR KEGG; mmu:21853; -. DR UCSC; uc007hlv.2; mouse. [Q9R1X4-1] DR UCSC; uc007hlw.2; mouse. [Q9R1X4-2] DR CTD; 8914; -. DR MGI; MGI:1321393; Timeless. DR eggNOG; NOG328380; -. DR GeneTree; ENSGT00390000015124; -. DR HOVERGEN; HBG079258; -. DR InParanoid; Q9R1X4; -. DR KO; K03155; -. DR OMA; RKGTQIV; -. DR OrthoDB; EOG7WDN1T; -. DR PhylomeDB; Q9R1X4; -. DR TreeFam; TF312802; -. DR NextBio; 301334; -. DR PRO; PR:Q9R1X4; -. DR ArrayExpress; Q9R1X4; -. DR Bgee; Q9R1X4; -. DR CleanEx; MM_TIMELESS; -. DR Genevestigator; Q9R1X4; -. DR GO; GO:0000790; C:nuclear chromatin; IEA:Ensembl. DR GO; GO:0005634; C:nucleus; IDA:UniProtKB. DR GO; GO:0005515; F:protein binding; IPI:UniProtKB. DR GO; GO:0046982; F:protein heterodimerization activity; IDA:UniProtKB. DR GO; GO:0042803; F:protein homodimerization activity; IDA:MGI. DR GO; GO:0048754; P:branching morphogenesis of an epithelial tube; IMP:MGI. DR GO; GO:0044770; P:cell cycle phase transition; IEA:Ensembl. DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW. DR GO; GO:0007623; P:circadian rhythm; IEP:UniProtKB. DR GO; GO:0030324; P:lung development; IMP:MGI. DR GO; GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0002009; P:morphogenesis of an epithelium; IEP:UniProtKB. DR GO; GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI. DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 1: Evidence at protein level; KW Alternative splicing; Biological rhythms; Cell cycle; Cell division; KW Complete proteome; Developmental protein; DNA damage; Mitosis; KW Nucleus; Phosphoprotein; Reference proteome; Transcription; KW Transcription regulation. FT CHAIN 1 1197 Protein timeless homolog. FT /FTId=PRO_0000072539. FT REGION 1 309 Required for homodimerization and for FT interaction with CRY1 and CHEK1. FT REGION 1079 1197 Required for nuclear localization. FT COMPBIAS 655 687 Glu-rich. FT COMPBIAS 964 1172 Glu-rich. FT MOD_RES 1165 1165 Phosphoserine (By similarity). FT VAR_SEQ 1 721 Missing (in isoform 4 and isoform 5). FT /FTId=VSP_051694. FT VAR_SEQ 952 952 Missing (in isoform 2, isoform 3 and FT isoform 4). FT /FTId=VSP_051695. FT VAR_SEQ 967 1104 Missing (in isoform 3). FT /FTId=VSP_051696. FT VAR_SEQ 1177 1177 Missing (in isoform 6). FT /FTId=VSP_051697. FT CONFLICT 179 179 I -> V (in Ref. 6; AAH64788). FT CONFLICT 298 298 H -> R (in Ref. 6; AAH64788). FT CONFLICT 317 317 R -> G (in Ref. 6; AAH64788). FT CONFLICT 583 583 A -> V (in Ref. 4; BAA76390). FT CONFLICT 744 744 L -> H (in Ref. 5; AAD24467). FT CONFLICT 846 846 H -> Y (in Ref. 5; AAD24467). FT CONFLICT 956 956 K -> R (in Ref. 5; AAD24467). FT CONFLICT 1068 1068 P -> L (in Ref. 5; AAD24467). FT CONFLICT 1190 1190 F -> L (in Ref. 4; BAA76390). FT CONFLICT 1196 1196 D -> G (in Ref. 4; BAA76390). SQ SEQUENCE 1197 AA; 137503 MW; DB24B7F0F3D05787 CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDSSVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKSID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQT PEQLAGVGQG RLAQERSTDV AELEVLRQRE MAEKRARALQ RGNRHSRFGG SYIVQGLKSI GEKDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLRERA QQHDETYYMW AMAFFMAFNR AATFRPGLVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDEA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLR DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKKKKKVQD QGVAFSQSPG ELEAMWPALA EQLLQCAQDP ELSVDPVVPF DAASEVPVEE QRVEAMVRIQ DCLTAGQAPQ ALALLRSARE VWPEGNAFGS PVISPGEEMQ LLKQILSTPL PRQQEPEEGD AEEEEEEEEE EELQVVQVSE KEFNFLEYLK RFASSTIVRA YVLLLRSYRQ NSAHTNHCIA KMLHRLAHGL GMEALLFQLS LFCLFNRLLS DPAAAAYKEL VTFAKYIIGK FFALAAVNQK AFVELLFWKN TAVVREMTQG YGSLDSGSSS HRAPLWSPEE EAQLQELYLA HKDVEGQDVV ETILAHLKVV PRTRKQVIHH LVRMGLADSV KEFQKRKGTQ IVLWTEDQEL ELQRLFEEFR DSDDVLGQIM KNITAKRSRA RVVDKLLALG LVSERRQLYK KRRKKLAPSC MQNGEKSPRD PWQEDPEEED EHLPEDESED EESEEGLPSG QGQGSSSLSA ENLGESLRQE GLSAPLLWLQ SSLIRAANDR EEDGCSQAIP LVPLTEENEE AMENEQFQHL LRKLGIRPPS SGQETFWRIP AKLSSTQLRR VAASLSQQEN EEEREEEPEP GVPGEQGPSE EHRTEALRAL LSARKRKAGL GPTEEEATGE EEWNSAPKKR QLLDSDEEED DEGRRQAVSG TPRVHRKKRF QIEDEDD // ID TIM_RAT Reviewed; 1205 AA. AC Q9Z2Y1; DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot. DT 01-MAY-1999, sequence version 1. DT 03-SEP-2014, entry version 75. DE RecName: Full=Protein timeless homolog; DE Short=rTIM; DE AltName: Full=Timeless-like protein; DE Short=rTLP; GN Name=Timeless; OS Rattus norvegicus (Rat). OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; OC Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; OC Muroidea; Muridae; Murinae; Rattus. OX NCBI_TaxID=10116; RN [1] RP NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, SUBCELLULAR LOCATION, RP AND INTERACTION WITH PER2. RC STRAIN=Wistar; TISSUE=Hypothalamus; RX PubMed=11112428; DOI=10.1006/bbrc.2000.3927; RA Sakamoto S., Miyazaki K., Fukui H., Oishi K., Hayasaka N., Okada M., RA Kamakura M., Taniguchi T., Nagai K., Ishida N.; RT "Molecular characterization and nuclear localization of rat timeless- RT like gene product."; RL Biochem. Biophys. Res. Commun. 279:131-138(2000). RN [2] RP FUNCTION. RX PubMed=10963667; DOI=10.1073/pnas.97.18.10038; RA Li Z., Stuart R.O., Qiao J., Pavlova A., Bush K.T., Pohl M., RA Sakurai H., Nigam S.K.; RT "A role for Timeless in epithelial morphogenesis during kidney RT development."; RL Proc. Natl. Acad. Sci. U.S.A. 97:10038-10043(2000). RN [3] RP TISSUE SPECIFICITY, AND INDUCTION. RX PubMed=15094047; DOI=10.1016/S0014-5793(04)00322-9; RA Muehlbauer E., Wolgast S., Finckh U., Peschke D., Peschke E.; RT "Indication of circadian oscillations in the rat pancreas."; RL FEBS Lett. 564:91-96(2004). CC -!- FUNCTION: Plays an important role in the control of DNA CC replication, maintenance of replication fork stability, CC maintenance of genome stability throughout normal DNA replication CC and in the regulation of the circadian clock. Involved in the CC determination of period length and in the DNA damage-dependent CC phase advancing of the circadian clock. Negatively regulates CC CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of CC PER1 possibly via translocation of PER1 into the nucleus. Forms a CC complex with TIPIN and this complex regulates DNA replication CC processes under both normal and stress conditions, stabilizes CC replication forks and influences both CHEK1 phosphorylation and CC the intra-S phase checkpoint in response to genotoxic stress. CC Timeless promotes TIPIN nuclear localization. Involved in cell CC survival after DNA damage or replication stress. May be CC specifically required for the ATR-CHEK1 pathway in the replication CC checkpoint induced by hydroxyurea or ultraviolet light. May also CC play an important role in epithelial cell morphogenesis and CC formation of branching tubules. CC -!- SUBUNIT: Homodimer or homomultimer. Component of the circadian CC core oscillator, which includes the CRY proteins, CLOCK or NPAS2, CC ARTNL/BMAL1 or ARTNL2/BMAL2, CSKN1D and/or CSNK1E, TIMELESS, and CC the PER proteins. Interacts directly with PER1, PER2 and PER3; the CC interaction with PER2 is via its second PAS domain. Interacts with CC CRY1, CRY2, CHEK1, ATR and ATRIP. Interacts with CLSPN and TIPIN. CC -!- SUBCELLULAR LOCATION: Nucleus. CC -!- TISSUE SPECIFICITY: Expressed in all tissues examined including CC brain, eye, lung, heart, liver, kidney, pancreas, placenta and CC testis. Highest levels of expression in eye, lung, liver, placenta CC and kidney. Expressed throughout the suprachiasmatic nucleus CC (SCN). CC -!- INDUCTION: In both brain and pancreas, no circadian oscillation CC was detected. CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AB019576; BAA34400.1; -; mRNA. DR PIR; T13959; T13959. DR RefSeq; NP_112630.1; NM_031340.1. DR UniGene; Rn.31755; -. DR ProteinModelPortal; Q9Z2Y1; -. DR PaxDb; Q9Z2Y1; -. DR PRIDE; Q9Z2Y1; -. DR GeneID; 83508; -. DR KEGG; rno:83508; -. DR UCSC; RGD:620939; rat. DR CTD; 8914; -. DR RGD; 620939; Timeless. DR eggNOG; NOG328380; -. DR HOVERGEN; HBG079258; -. DR KO; K03155; -. DR PhylomeDB; Q9Z2Y1; -. DR NextBio; 615946; -. DR PRO; PR:Q9Z2Y1; -. DR Genevestigator; Q9Z2Y1; -. DR GO; GO:0005634; C:nucleus; IDA:UniProtKB. DR GO; GO:0005515; F:protein binding; IPI:UniProtKB. DR GO; GO:0001658; P:branching involved in ureteric bud morphogenesis; IMP:MGI. DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEA:UniProtKB-KW. DR GO; GO:0007623; P:circadian rhythm; ISS:UniProtKB. DR GO; GO:0001822; P:kidney development; IMP:RGD. DR GO; GO:0007067; P:mitotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0002009; P:morphogenesis of an epithelium; IEP:UniProtKB. DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; ISS:UniProtKB. DR GO; GO:0042753; P:positive regulation of circadian rhythm; IMP:RGD. DR GO; GO:0006351; P:transcription, DNA-templated; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 1: Evidence at protein level; KW Biological rhythms; Cell cycle; Cell division; Complete proteome; KW Developmental protein; DNA damage; Mitosis; Nucleus; Phosphoprotein; KW Reference proteome; Transcription; Transcription regulation. FT CHAIN 1 1205 Protein timeless homolog. FT /FTId=PRO_0000072540. FT REGION 1 309 Required for homodimerization and for FT interaction with CRY1 and CHEK1 (By FT similarity). FT REGION 1081 1205 Required for nuclear localization (By FT similarity). FT COMPBIAS 655 685 Glu-rich. FT COMPBIAS 966 1178 Glu-rich. FT MOD_RES 1169 1169 Phosphoserine (By similarity). SQ SEQUENCE 1205 AA; 138565 MW; C118B6ACF1DDA03D CRC64; MDLYMMNCEL LATCSALGYL EGGTYHKEPD CLESVKDLIR YLRHEDETRD VRQQLGAAQI LQSDLLPILT QHRQDKPLFD AVIRLMVNLT QPALLCFGSV PKDPTVRHHF LQVLTYLQAY KEAFASEKAF GVLSETLYEL LQLGWEDRQE EDNLLIERIL LLVRNILHVP ANLEQEKRID DDASIHDRLL WAIHLSGMDD LLLFLSSSSA EQQWSLHVLE IISLMFRDQK PEQLAGVGQG RLAQERSTDL AELEVLRQRE VAEKRARALQ RGNRHSRFGG SYVVQGLKSI GERDVVFHKG LHNLQNYSSD LGKQPRRVPK RRQAAQELSV HRRSVLNVRL FLRDFCSEFL ENCYNPLMGA VKDHLLREKA QQHDETYYMW AMAFFMAFNR AAAFRPGFVS ETLSIRTFHF VEQNLTNYYE MMLTDRKEAA SWARRMHLAL KAYQELLATV NEMDMCPDDA VRESSRIIKN NIFYMMEYRE LFLALFRKFD ERYHPRSFLC DLVETTHLFL KMLERFCRSR GNLMVQNKRK KRKKKKKAQE QGVAFSRSPE ELQAMWSALA ERLLQCAQEP ELSVDSIIPF DAASEVPVEE QRVEAMVRIQ DCLVAGQAPQ ALALLRSARE VWPEGNVFGS PVISPGEEMQ LLKQILSATL PRQQEPVEGD AEEEDEEEEE EEEEELQVVQ VSEKEFKFLD YLKRFACSTI VRAYVLLLRS YRQNSAHTNH CIAKMLHRLA HDLGMEALLF QLSLFCLFNQ LLSDPAAAAY KELVTFAKYI LGKFFALAAV NQKAFVELLF WKNTSVVREM TQGYGSLDSG SCSHRAPVWS SEEEAQLQEL YLAHKDVEGQ DVVETILAHL KAVPRTRKQV IHHLVRMGLA DSVKDFQRKG TQIVLWTEDQ ELELQRLFEE FQDSDDVLGH IMKNITAKRS RARVVDKLLA LGLVSERRQL HKKRRKKLAP SCMQNGEESQ RDAWQEDPEE EEEKEGLPES EGEENEEDLL AGQVQGSSSL SAENLRQSLC QDGLSAPLLW LQSSLIRAAD DREEDGCSQA IPLVPLTEEN EEAMENKQFQ HLLRKLGIRA PCSGQETFWR IPAKLSSTQL RRVAASLSER ENKEEREEEP EPNPGVPGEQ SPSEEHQVRA PRALLSARKR KAGLVFPKEE ATGEEEWKSV PKKQQLLDSD EEDTDDERGG QAAVSGTLRI HKEKRFLVED EDEDY // ID TOF1_ASHGO Reviewed; 1265 AA. AC Q752A3; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 09-JAN-2013, sequence version 2. DT 14-MAY-2014, entry version 53. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=AFR672C; OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL OS Y-1056) (Yeast) (Eremothecium gossypii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Eremothecium. OX NCBI_TaxID=284811; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056; RX PubMed=15001715; DOI=10.1126/science.1095781; RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S., RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A., RA Gaffney T.D., Philippsen P.; RT "The Ashbya gossypii genome as a tool for mapping the ancient RT Saccharomyces cerevisiae genome."; RL Science 304:304-307(2004). RN [2] RP GENOME REANNOTATION, AND SEQUENCE REVISION TO 408 AND 410. RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056; RX PubMed=23749448; DOI=10.1534/g3.112.002881; RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.; RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type RT loci, numerous translocations, lack of transposons, and distinct gene RT duplications."; RL G3 (Bethesda) 3:1225-1239(2013). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AE016819; AAS54044.2; -; Genomic_DNA. DR RefSeq; NP_986220.2; NM_212356.2. DR STRING; 33169.AGOS_AFR672C; -. DR PRIDE; Q752A3; -. DR GeneID; 4622509; -. DR KEGG; ago:AGOS_AFR672C; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1265 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301727. SQ SEQUENCE 1265 AA; 144220 MW; 29939D41962BE089 CRC64; MEEMVSQNTE GDKSIDDHWQ TEGAETQPGL HETFPLGVLK ARVALLATAI GGPDHTSEQE AAPYKLGDDC LACLKDLKRW FVLVDQKQKR WDVASAAAEF RILEEDLIPI LVQWEQKMSQ GIKQSKVSGL PLSECIKNKQ YHGKIALNAF QLMVWMTWPM TLNEESSKNQ VHHYSGLKKH QLAYKKAILQ AHGGKVVKAA VRIATEVIKI DRLDRSVQDN SLIRLVLNFL RNILAIEPGE VTVSAKQLSK SRNINTSDML PPNISVDDIC LNSVVSVFKK FKVFPFLLTI SSSMGHEFEA EYVCLPLLEV AFYLTKDIDP HLLSLKADNP PQSLQNCGNK VSNGQGVVSG QLGMELIHLL DKERHHKMSQ IRSSSTRHSR FGGFFSIQTP NNGRLTISNG HSALDHDLAL NNIDKKKKWN KTTRNTAEAV QGIPVGVLNG EFNLTFLSHD NRSCLKWFLA NFVDSSFNIL LKNLIDYFTA DEFNQQILQK LQFLLFYAWF LKFERDRCQK GETDGIFVSE ALQDTSHILI IKFLREAHEL KKWPLVHAAM LAITELLNYL DVLGEDWEED VVGIYTKIFS NERLKLFSTI PRTASRHSLH YVKACINMNH AIMTTLERFN KNNKDLIIKG FRKRMITRFI VKEGKTTSGD VNGNKNGQDT TRDADEDAIS SDEETNMISA RLDFKKVLDA YFNGTVIDTY IFYLKHFTEL TEEDIKRVLY FLNHILCSNE ESFLFRVDFM IVLKEMLAPG GLSVTGHTRI RINEFSDHFM AKLKRKLEKS PFWYINILFP NLHDRELGYY LRYGQQRPNT QSIHKVVAPT MFKHIEGEEN MSEQQLKDLK IGVLVSTLLD DGKNHFVEEI NRIFKLVVEG YEKHYQNNER SATLHYPRVD FRSDMFDMKR ALLFDSDLRA LMTTLGYHVA DTEVEPCYIG GIFYFPDLSS ALNSLEQYMA IPFHTPNGLP SSSYLLRSID YKSGVDADAK VGEAMRIDQF SDEMADMALS ENANRYFEDL NRMEERLEGK QIPRGTAKKR SAIKPKSRKS QPTGIGGIDD DTPVINKSKR KKQLFLSNEF IMDSDDEEEL VASPIFYENE IYLRFILNKY QGNLPSHLFS VFSRFANERG RMAGAVVGDY TDLFNGPVPS IEELKSMENS TTHHGLKEIL QLQPRDHLSL SPNNENNSAH SSENLSSDSE NDNITNDIPL SDSEYNSSNS SQYANTAKTS IIDPPSSKTS LLKLALTHEA DVESEDDFIP RKRARKVRLE DGEEY // ID TOF1_ASPCL Reviewed; 1178 AA. AC A1C928; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 1. DT 14-MAY-2014, entry version 30. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=ACLA_053980; OS Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC OS 3887 / NRRL 1). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=344612; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1; RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046; RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., RA Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., RA Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., RA Galens K., Fraser-Liggett C.M., Haas B.J., Inman J.M., Kent R., RA Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., RA Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., RA Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., RA Jiang B., Denning D.W., Nierman W.C.; RT "Genomic islands in the pathogenic filamentous fungus Aspergillus RT fumigatus."; RL PLoS Genet. 4:E1000046-E1000046(2008). CC -!- FUNCTION: Forms a fork protection complex (FPC) with csm3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of tof1 and csm3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS027048; EAW13352.1; -; Genomic_DNA. DR RefSeq; XP_001274778.1; XM_001274777.1. DR STRING; 5057.CADACLAP00005220; -. DR EnsemblFungi; CADACLAT00005331; CADACLAP00005220; CADACLAG00005331. DR GeneID; 4707118; -. DR KEGG; act:ACLA_053980; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1178 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301728. SQ SEQUENCE 1178 AA; 135716 MW; 2E86E4A0AF1323D0 CRC64; MDDEGAPLSE SAQVVDPDVR AHVYSLVTAL GGFNGENADR YVLGDDALAC LRDIKRWLKL HDEKNNRMDV ARCLGEANLV NGDLLPILTL WSTSGQNSKF MSRIALACLE LLVPLTWPLE LHSEMTVNHH RHTPYLQQAQ VLYKRGILGP GGSSLLRTII RIGLPSMAVP RSDRTTRDEG ILKLMLYLLR NIAVISPHSR LSAEGDEEET SRSATINAFQ DQDAFALLLT MCSNVADDFN LQDVVLLEIL FHIVKGVNVE KLFMNDTQRK AKRTEELGDL LQKESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QDVLKDSQTT LYKMDQSKKW NKPQVRRRQT EVTVNNDFNT PVNLNSTATK NLRIFIEEFL DSGFNPLFTH VRKAIEREAD RIMDINSRHY FYTVAWFLEA ERVRRKYQRE RHSQEDKSLK KMEPDSFALV ASVLNQETFV FLNRSMQKSF DNKEVEDLTA EMRCFTQILL TVQEMAQSPL DDDQEVADNI QNRIFYEETT HDRIISIIRG YKDQGFGYLD ACTQLAHVFL RMLEHYSKEN VDMQIRSRRR IKRKAKQDDQ AIDVEDEEHA SEDEELMEAE RVSKERKFDF KRFAAKFCNQ KCVDTFVAFI KYYKELNTDQ LKRAHRYFYR IAFKQEMSVL LFRLDIINLF YRMIKGPGAL DSSKPIFKEW EELVRQILRR MIKKIDQRPA LITELLFSKI NSTVFYLEFG FEKQTISVSK RPPAELEVDP REAKTTDEKL SIVVRVMIKD EHINLVKWIS EVLRLAADER ESWESREQQP GEPTAPNPMI PVKPDDEACQ KAMFSNAKLR LLMTLIGFER LGMEDVPGAS WVVPSSFTSD DLRHTKRVID QCLIEPATED PDQDLSRLIR RKYANDARGG GRDEQNLDID FGSDSEGEDN VPDGPLFPPN HRSKANALDQ LKKQRQKRRK EDGDRETPDD EVLEERRRAR LENALARQAK IKSDLYIHAS DEESDEEADE EFFRLEEQRR KEQAARIKHA LLHGVVEEIS DKSSKKTGRK RQSDQHTTLN IDAHTKRQRR KNRTDKLDEG DDLVMAGTEA QSPDSPGLGS SSHDAKGIEN TPLTSDEDEL EFDDDLAFSR DRNRRKDFTP NVDKMVIEPA QQDADPAAPD EDDDEDAPVV GSSRRRVRGG FVIESDSE // ID TOF1_ASPFU Reviewed; 1176 AA. AC Q4W9M7; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 17-APR-2007, sequence version 2. DT 14-MAY-2014, entry version 47. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=AFUA_4G04390; OS Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC OS A1100) (Aspergillus fumigatus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=330879; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100; RX PubMed=16372009; DOI=10.1038/nature04332; RA Nierman W.C., Pain A., Anderson M.J., Wortman J.R., Kim H.S., RA Arroyo J., Berriman M., Abe K., Archer D.B., Bermejo C., Bennett J.W., RA Bowyer P., Chen D., Collins M., Coulsen R., Davies R., Dyer P.S., RA Farman M.L., Fedorova N., Fedorova N.D., Feldblyum T.V., Fischer R., RA Fosker N., Fraser A., Garcia J.L., Garcia M.J., Goble A., RA Goldman G.H., Gomi K., Griffith-Jones S., Gwilliam R., Haas B.J., RA Haas H., Harris D.E., Horiuchi H., Huang J., Humphray S., Jimenez J., RA Keller N., Khouri H., Kitamoto K., Kobayashi T., Konzack S., RA Kulkarni R., Kumagai T., Lafton A., Latge J.-P., Li W., Lord A., RA Lu C., Majoros W.H., May G.S., Miller B.L., Mohamoud Y., Molina M., RA Monod M., Mouyna I., Mulligan S., Murphy L.D., O'Neil S., Paulsen I., RA Penalva M.A., Pertea M., Price C., Pritchard B.L., Quail M.A., RA Rabbinowitsch E., Rawlins N., Rajandream M.A., Reichard U., RA Renauld H., Robson G.D., Rodriguez de Cordoba S., Rodriguez-Pena J.M., RA Ronning C.M., Rutter S., Salzberg S.L., Sanchez M., RA Sanchez-Ferrero J.C., Saunders D., Seeger K., Squares R., Squares S., RA Takeuchi M., Tekaia F., Turner G., Vazquez de Aldana C.R., Weidman J., RA White O., Woodward J.R., Yu J.-H., Fraser C.M., Galagan J.E., Asai K., RA Machida M., Hall N., Barrell B.G., Denning D.W.; RT "Genomic sequence of the pathogenic and allergenic filamentous fungus RT Aspergillus fumigatus."; RL Nature 438:1151-1156(2005). CC -!- FUNCTION: Forms a fork protection complex (FPC) with csm3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of tof1 and csm3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAHF01000016; EAL84586.2; -; Genomic_DNA. DR RefSeq; XP_746624.2; XM_741531.2. DR STRING; 5085.CADAFUAP00001371; -. DR EnsemblFungi; CADAFUAT00001371; CADAFUAP00001371; CADAFUAG00001371. DR GeneID; 3503983; -. DR KEGG; afm:AFUA_4G04390; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1176 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301729. SQ SEQUENCE 1176 AA; 134897 MW; 236EADF236015816 CRC64; MDEEGAPLSE GVQVVDPDVR AHVYSLVTAL GGFNGESADR YVLGDDALAC LRDIKRWLKL YDEKHNRMDV ARCLGEANLV NGDLLPILTL WSTSGQKSKH MSRIALACLE LLVPLTWPLE VHSEMTVNHH RHTPYLQQAQ VLYKRGILSH GSGSILRTII RIGLPSMAVP RSERTTRDEG ILKLMLYFLR NIAVISPNAR LAAEGDEEET SRSATINAFQ NQDAFALLLT MCSNVGEDFS LQDVVLLEIL FHIVKGVNVE KLFMNDAQRK AKRTDELGEL LQKESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QDVLKDSQTT LHKMDQSKKW NKPQIRRRAA EVTANNDFNT PVNINSTATK NLRMFVEEFL DSGFNPLFTH VRKAIEREAD RVMDINTRQF FYTVAWFLEA ERVRRAHQRE KRHLGDTPLK EIEPDSFALV ASVLNQETFV FLNRSMQYSY DNKDVEDLTA EMRCFTQILL TVQEMAQSPL EEDQEIADNI QNRIFYEETT HDRIVAIVRG YKDQGFGYLD ACTELAHVFL RMLEHYSKEN VDMHVRSRRR AKRKAKQAKQ ADIEGDDEEE ASEEEDLMDV ERISKERKFD FRRFAAKFCN QSCVDTFIAF TKYYRELNVD QLKRAHRYFY RIAFKQEMSV LLFRLDIINL FYRMIKGPGA LDSNKPIFKE WEELVRQIIR RMIKKIDQRP ALITELLFSK INSTVFYLEY GHEKQTISAS KRPPAELEVE PREAKTIDEK IRIVVHVMVK DEHTDLVKWV SDVLNSAADE REAWESQEQH SGGQKAPNPM IPVKSDNESC QKAMFSNAKL RLLMSLVRFE RLGMEDVPGA SWVVPSSLNS QELRHTRSII EQCLTEPVTE NSDRDLSQLI RRKSGNNTRR DRDDQMANVD FGSDSEGDDN VPDGPLFPPN PRSRANALEQ LKKQRKKRRK QAGEEEEPDE EDLEARRRAR LENALARQAK IKSDLYIHAS DEETDEEADQ EFFRLEEQRR KEQAERIRKA LLHGVVEEVS ENSRKKSSGR KRQSDQYTAS TADSQSKRQR RLQQTEGLDG NDDLVVAGTE ARSPDSLGQG SPSLKGANDV EDTLVTSEEN ELDFDDDLAF SRNRTRDKVL SAENDDSDTE PPAPDTIDED GEEAAAVAAP PRRRVRAGFV IESDSE // ID TOF1_ASPNC Reviewed; 1169 AA. AC A2R2E3; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 11-SEP-2007, sequence version 2. DT 14-MAY-2014, entry version 34. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=An14g00440; OS Aspergillus niger (strain CBS 513.88 / FGSC A1513). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=425011; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CBS 513.88 / FGSC A1513; RX PubMed=17259976; DOI=10.1038/nbt1282; RA Pel H.J., de Winde J.H., Archer D.B., Dyer P.S., Hofmann G., RA Schaap P.J., Turner G., de Vries R.P., Albang R., Albermann K., RA Andersen M.R., Bendtsen J.D., Benen J.A.E., van den Berg M., RA Breestraat S., Caddick M.X., Contreras R., Cornell M., Coutinho P.M., RA Danchin E.G.J., Debets A.J.M., Dekker P., van Dijck P.W.M., RA van Dijk A., Dijkhuizen L., Driessen A.J.M., d'Enfert C., Geysens S., RA Goosen C., Groot G.S.P., de Groot P.W.J., Guillemette T., RA Henrissat B., Herweijer M., van den Hombergh J.P.T.W., RA van den Hondel C.A.M.J.J., van der Heijden R.T.J.M., RA van der Kaaij R.M., Klis F.M., Kools H.J., Kubicek C.P., RA van Kuyk P.A., Lauber J., Lu X., van der Maarel M.J.E.C., RA Meulenberg R., Menke H., Mortimer M.A., Nielsen J., Oliver S.G., RA Olsthoorn M., Pal K., van Peij N.N.M.E., Ram A.F.J., Rinas U., RA Roubos J.A., Sagt C.M.J., Schmoll M., Sun J., Ussery D., Varga J., RA Vervecken W., van de Vondervoort P.J.J., Wedler H., Woesten H.A.B., RA Zeng A.-P., van Ooyen A.J.J., Visser J., Stam H.; RT "Genome sequencing and analysis of the versatile cell factory RT Aspergillus niger CBS 513.88."; RL Nat. Biotechnol. 25:221-231(2007). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=CAK41843.1; Type=Erroneous gene model prediction; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AM270309; CAK41843.1; ALT_SEQ; Genomic_DNA. DR RefSeq; XP_001400673.2; XM_001400636.2. DR STRING; 5061.CADANGAP00010765; -. DR GeneID; 4986897; -. DR KEGG; ang:ANI_1_82124; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1169 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301730. SQ SEQUENCE 1169 AA; 134462 MW; 0FBED15D981A718D CRC64; MENEEPVLSA PDVQVVDPDV RAHVYSLVTA LGGFNGEDAD KYVLGDDALA CLRDIKRWLK LYDEKHNRMD VARCLGEANL VNGDLLPILA VWANSKKQTK YMSRIALACL ELLVPLTWPV ELHGELTINH HRHIPYIQHV HVSYKRGLLS HASTSYLRTI IRVGIPSMAI PRSERTTRDE GILKLLLYLL RNIALITPNT RLAAEGDEEE TSRSATINAF QDQDVFALLL TMCSNVGDDF TMQDVALLEI LFHLIRGVSV EKLFMDDAQR TAKRTDELDD LLRQESSLRR EYAKNAPTRH GRFGTMIWVK RDDAKYSTVS GQNVLKDGQA TLQKMDETKK WNKPLIRRKP QDLTVHNDFS TPVHLNSTAS NNLRMFVEEF LDSGFNPLLT HVRKAIEREA DRVMDINTRQ FLYTTAWFLE AERARRARQR KKHAESEKPA KELEPDSFGL VAGVLNQETF VFLNRAMQYA LDNKDWEDLN AGMRCFTQIL LTVQDMAQSP LEEDQEIAEN IQNRIFYEET THDRVLAVIR GYKDQPFGYL DACTELTHVF LRMLERYSKE NLDMQVRSRR RARRKAKDVE GTGNDENDEE NGSEDEDRLE AERVSKERKF DFRRFAAKFC NQKCVDTFVA FTKHYKELNT EQLKRAHRYF YRIAFKQELS VLLFRLDIIN LFYRMIKGPG ALDSSKPIFK EWEEFVRQII RRLTKRLDQR PALFVELLFS KINATTFYLE YGHERQTVTR ARKAPAELEI DPRQAHTIEE KISIMVPALV LDGEEDLVTW VSDVLESAVE EREAWETQEK ALRDAGAENS KIPNPMISVK ARDDACQQAM FSNAKLRLLM TLVKFERLGA EDVPGAAWII PSAPRAQDLR EMKSFIDKYF EKAKRGTLGR DPRELIRRKY GGGKTASDNQ HNPDIQFGDD SEGEDEVPDG PLFPPNPRAA PNPANKPTKK KKRKERNPDD EDEDDSVDEE TLEERRRARL ENSRARLAKI KSDLYVHASD EDTDEEGDKE FFLLEEQRRR EQAKRIKHAL LTGMTEDGDG STNKKGQRKR QTTRNRTGEA KSKRQRRGKQ ADEVDEDDDV VMGNMDAPSP MSDREGTPSG EEDDGFNFDD DLVFSRDREK LLGSAGNEEK DSNRPDKAMA QDEDDDDAPI VAANRRRMRA GFVVDSDSE // ID TOF1_ASPOR Reviewed; 1166 AA. AC Q2PIU8; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 24-JAN-2006, sequence version 1. DT 14-MAY-2014, entry version 37. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=AO090206000054; OS Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=510516; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 42149 / RIB 40; RX PubMed=16372010; DOI=10.1038/nature04300; RA Machida M., Asai K., Sano M., Tanaka T., Kumagai T., Terai G., RA Kusumoto K., Arima T., Akita O., Kashiwagi Y., Abe K., Gomi K., RA Horiuchi H., Kitamoto K., Kobayashi T., Takeuchi M., Denning D.W., RA Galagan J.E., Nierman W.C., Yu J., Archer D.B., Bennett J.W., RA Bhatnagar D., Cleveland T.E., Fedorova N.D., Gotoh O., Horikawa H., RA Hosoyama A., Ichinomiya M., Igarashi R., Iwashita K., Juvvadi P.R., RA Kato M., Kato Y., Kin T., Kokubun A., Maeda H., Maeyama N., RA Maruyama J., Nagasaki H., Nakajima T., Oda K., Okada K., Paulsen I., RA Sakamoto K., Sawano T., Takahashi M., Takase K., Terabayashi Y., RA Wortman J.R., Yamada O., Yamagata Y., Anazawa H., Hata Y., Koide Y., RA Komori T., Koyama Y., Minetoki T., Suharnan S., Tanaka A., Isono K., RA Kuhara S., Ogasawara N., Kikuchi H.; RT "Genome sequencing and analysis of Aspergillus oryzae."; RL Nature 438:1157-1161(2005). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AP007172; BAE65426.1; -; Genomic_DNA. DR RefSeq; XP_001826559.1; XM_001826507.2. DR ProteinModelPortal; Q2PIU8; -. DR STRING; 5062.CADAORAP00011975; -. DR EnsemblFungi; CADAORAT00012218; CADAORAP00011975; CADAORAG00012218. DR GeneID; 5998675; -. DR KEGG; aor:AOR_1_92044; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1166 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301731. SQ SEQUENCE 1166 AA; 134300 MW; 1FD107BD03124B9E CRC64; MNDEAVAFSQ AVQVVDPDVR AHVYSLVTAL GGFNGEDADR YVLGDDALAC LRDIRRWLKL YDEKYHRMDV ARCLGEANLV NGDLLPIFSL WWSTGQKSKY MSRIALACLE LLVPLTWPLE VHGEMTVNHH RHFPYLQHAQ VSYKRGLLSR GDLNFLRTII RIGLPSMAVP RSERTTRDDG ILKLMLYLLR NIVVIAPNAR LAADGDEEET SRSATINAFQ AQDVFALLLT MCSNVGDDFN MQDVILLEIL FHLVKGVNVQ KLFMDDAQRS AKHTDELDTL LKQESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QDVLKDSQAT LQKMDESKKW NRPQPRKTHE DSVLNNDFST PAHLNSTASR NLRMFVEEFL DSGFNPLFTH VRKALEREAD RVVPINSRQF FYTVAWFLDA ERARRARQQE MHLQNGKPMK ELERDGFGLV ASVLDQETLV FLNRSMQISF DQKDWEDLNA EMRCFTQILL TVQEMTQSLL EEDQEIAENI QNRIFYEETT HDRVLAIMRE YKGQGFGYLD ACTELSHVFL RMLERYSKEN VDMQVRSRRR SRRKNMETQV AAPEDNNEEH ASDDEDIMEA ERICRERKFD FKRFAAKFCN QKCVDTFVAF TKFFRELNSD QLKRAHRYFY RIAFKQEMSV LLFRVDILNL FYTMIKGPGA MDSSKPIFKE WEELVRQVIR RMIKKIDQRP ALITELLFSK MNSTLFYLEY GHERQTLPSV RRAPAELEVN PSEATTQEDK IKIVIGALVM DGQADLVAWV SNVLGTAAEE RESWEAYEDA QRDEAQGAPR APNPMIAVLP HDDACKQAMY FNAKLRLLMT LVGFERLGME DVVGASWVVP SSQGSKDLKG IKLTIDKCLE DPYTGDIEHD PRQMLRRKYK PDDKEHNRQT TLDVDFGSES EGEDVPDGPL FPPNPRSKAN APNDSKTRRK NREAVGEREP IDEDTLEARR KARQENTRAR LAKIKSELFV HASDDESDEE ADKEFFDLEE KRRKEQAARV RKALLTGVVD EIGRKANKKS ERKRLSNSGK SDTQSKRQRR GRTTEALDED DDIIMDGAVA RSSDHATEDD ENTSATSDED DEFDFDDNLA FRRDRDLDRD PVLPSHAEDM QPTDTRELRD NDENAPVATL ARRRLRAGFV IDSDSE // ID TOF1_ASPTN Reviewed; 1147 AA. AC Q0CU99; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 17-OCT-2006, sequence version 1. DT 14-MAY-2014, entry version 28. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=ATEG_02735; OS Aspergillus terreus (strain NIH 2624 / FGSC A1156). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=341663; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=NIH 2624 / FGSC A1156; RA Birren B.W., Lander E.S., Galagan J.E., Nusbaum C., Devon K., Henn M., RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., RA Engels R., Montgomery P., Pearson M., Howarth C., Larson L., Luoma S., RA White J., Alvarado L., Kodira C.D., Zeng Q., Oleary S., Yandava C., RA Denning D.W., Nierman W.C., Milne T., Madden K.; RT "Annotation of the Aspergillus terreus NIH2624 genome."; RL Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Forms a fork protection complex (FPC) with csm3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of tof1 and csm3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH476596; EAU37697.1; -; Genomic_DNA. DR RefSeq; XP_001211913.1; XM_001211913.1. DR STRING; 33178.CADATEAP00003781; -. DR EnsemblFungi; CADATEAT00003781; CADATEAP00003781; CADATEAG00003781. DR GeneID; 4317034; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1147 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301732. SQ SEQUENCE 1147 AA; 132551 MW; 4500FE6EA9E18C45 CRC64; MDEELAFGQT VEVVDPDVRA HVYSLVTALG GFNGEDADKY VLGDDALACL RDIRRWLKLY DEKYNRMDVA RCLGESNLVN GDLLPILSAW WHGNQGSRYM SRIALACKVE LLVPLTWPLE VHAEMPANHL RHIPYLQHVQ VLYKRGLLSR GHTPLLRAII RIALPSMAVS RSERTTRDEG ILKLMLYLLR NIAIISTNAR LAAEGDEEET SRSATINAFQ EQDAFALLLT MCSNVGDDFT MQDMVLLEIV FHLIKGVDVE KLFMSDAQRS AKRTDELSEL LSKETSLRRE YAKNAPTRHG RFGTMIWVKR DDAKMSTVSG QDVLKDSQAT LYKMDQSKKW NKPKQRQKQE LSVVNNDFDT PVHLNPIASK NLRMFVEEFL DSGFNPLFTH VRKAIEREAD RVMDINSRQY FYAVAWFLEA ERTRRVRQRE KHSQSEKAAK EFEPDSFSLI ASVLNQETFV FLNRSMQYSF DQKDWADLNA EMRCFTQILL TVQEMATSPL EEDQEIAENI QNRIFYEETT HDRILAIVRG YKDQGYGYLD ACTELSHVFL RMLERYSKEN TDMQIRSRRR AKRKKQLEQK GDENNGEEQD SEEEEMLEAE RVSKERKFDF RRFSAKFCNQ KCVDTFVSFA RFYRELNSDQ LKRLHRYFYR IAFKEEMSVL LFRVDIINLF YRMIKGPGGM DSTKPIFKEW EEFVRQLIRR MVKKIDQRPA LITEMLFSKI NSTMYYLEFG HEKQTISVTR RPPAELVVNP NDAETTEDKI KIVIGALVKD GKNRLVSWLS GVLDSAADER EAFEIQEAAE REENTRASRA PNPMIPVEPS DDDCKNEMFS NAKLRLLMAL VKFERLGVED IPGASWVVPA HLSSADIRDI KSTVDKCLAD PFQGTFDREP QAMLQRKFQR ENRGSFEPTQ EVSFGNDSEG EDTPEFLFPP NPRSKSNALE ELKKKRKKCK NDDGEKEPLD EQTIEERRRA REENARSRQA KIKSDLYVHA SDEESDDEAD EEFFRLEEKR RKEQSERIRQ ALLLGKVEEL ANKAGKKTQR KRPSDPQIAG DSESQNKRLR QDIPEDDDDL IMGGSEPDSP GLQTGDHDSD DDLRFEDDLA FRRNRESSAA SDRNGPPGEA KEDEDTPVAA SGRRRMRAGF VIDSDSE // ID TOF1_CANAL Reviewed; 1263 AA. AC Q59NW5; Q59NR6; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 26-APR-2005, sequence version 1. DT 14-MAY-2014, entry version 36. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=CaO19.11613, CaO19.4136; OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; mitosporic Saccharomycetales; OC Candida. OX NCBI_TaxID=237561; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SC5314 / ATCC MYA-2876; RX PubMed=15123810; DOI=10.1073/pnas.0401648101; RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., RA Magee B.B., Newport G., Thorstenson Y.R., Agabian N., Magee P.T., RA Davis R.W., Scherer S.; RT "The diploid genome sequence of Candida albicans."; RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=EAK92109.1; Type=Frameshift; Positions=624, 629; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AACQ01000202; EAK92109.1; ALT_FRAME; Genomic_DNA. DR EMBL; AACQ01000200; EAK92158.1; -; Genomic_DNA. DR RefSeq; XP_711340.1; XM_706248.1. DR RefSeq; XP_711388.1; XM_706296.1. DR PRIDE; Q59NW5; -. DR GeneID; 3646993; -. DR GeneID; 3647045; -. DR KEGG; cal:CaO19.11613; -. DR KEGG; cal:CaO19.4136; -. DR CGD; CAL0068980; YBL053. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1263 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301733. FT VARIANT 157 157 I -> T (in allele CaO19.4136). FT VARIANT 356 356 A -> V (in allele CaO19.4136). FT VARIANT 391 391 S -> T (in allele CaO19.4136). FT VARIANT 536 536 S -> P (in allele CaO19.4136). FT VARIANT 1046 1046 S -> L (in allele CaO19.4136). FT VARIANT 1246 1246 S -> L (in allele CaO19.4136). SQ SEQUENCE 1263 AA; 144961 MW; 741B27699F3C183E CRC64; MSDYESGSDI DNYYEADEFD DFIEYSDNEV EQEKSKPTPG QIEVEEIEEP EEDRIRTLTT TLKPNETQAQ KLLKAHISVL VSALGGPDHT SDIQPPPYKL GHDALACLKD IKRWIRAVDE KKNNYEVALA CAESGLVTND LIVIMCQWED KMQKKEIIKN KTTTEKTMLA CLELLVLLTW PVEFGKDLSE SQKLLYSEIK KVHVSYKKQI LMFNNGQLLK AAIRLVLPTI AKSRIDREPR DNQILKLVLY LIRNLLAIEP ANLSISNKSR KGASVTASDL PLGVTQDDIS INNVLSVFKK NKVLMLLLTI SGSLGTEFDR DMFGEICLES IYLIIKGLSA SEVLVKKNLG STPVAAPSQN TVPDAINASQ PLQPVTTTVG MQLQDLLATE SKKKKIQTQN IASRHGRFGS LLSIRSADSN SFVVSGQEAL INTDSSLAKL DKSKKWKDRT YFKYDSDEYV NTSTPVYLNL TGQDILYNFV EQFLSGGCFN NLIECMGSRL TSQTDLNMVD ELTLASYFFT ISWFLSYQRE RIGLDSENKE LNYGSVGAAL SEVNFILIIG YFRDSFSVKK WNSLHVAMIC FKELLQISNS VFGKEITNQT GEGDEISQHE IDRELAEGII RKLFSFNDFL SIIVQIPQTA AKHSPDYLRV SVSVVHILLK AFETFANEDV HLYIQSKRKQ SKRNRKRVNN LDKSTEDRLR DVIYASDEEL DQSSAKEITQ ERKLDFKKTE ARFFHQAIVS TYINYLSRYE DLSNQEIKTC LSYFHRLFVV RKDFTGLYRL DFMQLLQKLR NYLQRGSSLR LQVEEFIYYF MKKFKTAFER FPMPIEVLFP RFEDNECKVY LATGEVYEKE ETTSTSRSPR LAKDLEFVRD FGLDDQIKIL VSQLHVQEKQ SLLKWLIQEL ERIINDRILN SDSIAELNAS NQHRRLFINN GYLRFLLRII GFDLPYTMEE VPELATTVDM EHLTKVTELI KKWDSSQPVI FEDDKVPSYF VRTREAGYDE DQYNENDQEY DFNDDSIAFE TEANPNSNRN HVSELDHLEE LERQLSSNGS RVNSKERNGT KGKARKKSKE KKRPEPKKVR GLKRRRIPKD LLDDDDSQHV VKSAEFVHDS DDESDDEKDK AFFEREEKMR NLLNDMGGIA TSEQLKEIQK VWKNLETGGN NKVASTVAKA VKEVGLFVEE SDNDDEVEEE SRNSAPVNEE ADRTIFESGE VDTQQDLSDN TSNTSDMESE TETTKRSFVE DPEEISHVQP KRKRLVISDD EEE // ID TOF1_CANGA Reviewed; 1176 AA. AC Q6FNX7; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 19-JUL-2004, sequence version 1. DT 14-MAY-2014, entry version 44. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=CAGL0J08250g; OS Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / OS NRRL Y-65) (Yeast) (Torulopsis glabrata). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Nakaseomyces; OC mitosporic Nakaseomyces. OX NCBI_TaxID=284593; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., RA Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., RA Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., RA Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., RA Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., RA Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., RA Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., RA Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., RA Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., RA Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., RA Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., RA Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., RA Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CR380956; CAG61018.1; -; Genomic_DNA. DR RefSeq; XP_448067.1; XM_448067.1. DR GeneID; 2889924; -. DR KEGG; cgr:CAGL0J08250g; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1176 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301734. SQ SEQUENCE 1176 AA; 135249 MW; 27C925FDEBE21EC6 CRC64; MSDTESPLTV LKARIALLAT AIGGPDYTSQ IDPPPYQIGD DCLACLKDLK RWFRLVDDNQ RRWDVAMAVA EYKILTDDLL PILIDWENKC YLATKLSKGN SDISAHFKNK QYYDKIALNC LQLMVLMTWP LILTEQSSTN QINLYSELKK HQLTYKKAIL SVENGKVLKA AIRIAIDVIK LDRLARTPRD NMVLKMVLNF IRNILAIEPG ELTITARKNI ASKGINSVDT LPPNVTQDDI SQSTVISCFK KNKVFPFLLT LGSSMTKEFD QDFINIPLME VMFFLTKDIS QDSLLFKSGE LDTAQSENHL SKAGQELNDL LQKESQLKKK VIMNTSTRHS RFGAMLSIQT LDQKRLTVSG SQNLLDNSKA LQKIDDSKKS KGRRPMIRNE TDNESLPTNL LNVHKKSGTY LPLTISKYLN DFINDFIDSS FNYLLKSVTN YFVTEEDKII SLEKIEYLLF FAWFNKYQIL RCQVDKDADI MMISESIKET TFILVSSLLR SSYDSKAWAV VHSSMLAFNE LLKLVNSLKK FEDNEDIEYV LSRLFSDERI QLLSNLPRIA STHSLSFMKT SIELTHTVLK ILEMYSGDNS LVVESKRRAK KMKSISKEDY ERLVNEEGYD PDEAIEILNP GHKTIVINFK RVQSSFFHRN TIDLYINTLK RFNELEYSHI KMIISFLYRL FVENNEETLF YRLDFIILLK DMLKQDGLPR TSKARTHIND FAKYYLSRLK RKLKSSPAWH VGILFPPLND GVVGYFQKYG EHKMTKESEI YAVQPSQFIP FEQQEMMSEN MILDMQIGVL VSTLIDEGSQ NLVELVRENV QHLIAVFTSH LEVAGENEKT PNNEAFILKE EYDVNPLHYN RHIRALLQLV GFEIPILKSD PCFYRGTTEF SRLVKCEESI TKYLNIPFET PNGLPSSSYL KQQSEKNNSL ESDGWKGNED YDYTDPNIVP DNEVDDNDYF KDLDKSTNIR KEKRTVGIAS KKTQSKNKTS RNRKKASFRL PNAIEGKDKQ PQENLEVFSK EYISDSDEDD EEILNPVFFE NEMYMRWLLD KYNGQLPNDK FLSFGRFVNE RLSNNGKVVS DFTSLFDGPV PPIDALPLEG ITRKGPDKTL LTLSRVEINE SNQDNENTQV NEQVDETSEN LTINKNARNI GISHGHVESE ADDDEPITKK RRTSAN // ID TOF1_CHAGB Reviewed; 1251 AA. AC Q2HBI0; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 21-MAR-2006, sequence version 1. DT 14-MAY-2014, entry version 22. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=CHGG_02424; OS Chaetomium globosum (strain ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC OS 6347 / NRRL 1970) (Soil fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Chaetomiaceae; OC Chaetomium. OX NCBI_TaxID=306901; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 6205 / CBS 148.51 / DSM 1962 / NBRC 6347 / NRRL 1970; RG The Broad Institute Genome Sequencing Platform; RA Birren B.W., Lander E.S., Galagan J.E., Devon K., Nusbaum C., RA Ma L.-J., Jaffe D.B., Butler J., Alvarez P., Gnerre S., Grabherr M., RA Kleber M., Mauceli E.W., Brockman W., Rounsley S., Young S.K., RA LaButti K., Pushparaj V., DeCaprio D., Crawford M., Koehrsen M., RA Engels R., Montgomery P., Pearson M., Howarth C., Kodira C.D., RA Yandava C., Zeng Q., Alvarado L., Oleary S., Untereiner W.; RT "Annotation of the Chaetomium globosum CBS 148.51 genome."; RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases. CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH408030; EAQ90489.1; -; Genomic_DNA. DR RefSeq; XP_001228940.1; XM_001228939.1. DR GeneID; 4389167; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1251 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301735. SQ SEQUENCE 1251 AA; 140834 MW; B8AC10E031B533F3 CRC64; MEDVGVNNDT VHPEARAYIT SLVSALGGYG VDDDGGYTLG DDALEVLRDL KRWVRFYDER TNRMDVARCL AESNLVTSDL LQIMAKWVSN ESSSKYMERI AFACLEIMVP LTWPIERDSE TMTVNHHRHL PVLQLAQLGY KRAIINFDVA PILSTAVRIA LPCMAIPNGD RSSRDQATIK LILYFLRNIA MIAPPPGLKY EGDETQVSRS TLIDAFTFQD IFLTILTIAS NMGEDFRTED VIILDIIFHI VKRVDSSKLF VSEKRLHKIK EDELTAAMRK EAAMLKSYNK NAPTRHSRFG TMIWVKRESG KLATVSGQDA LLDAATRERK MDSNKSFKPP RRARKEDMEP KDLGPRVSLD ERARRQLQSF VSEFLDSGFN PLFSHVRRSL DREAPHVLQS HHSQFFYLVA WFLEAERMRK KAAKDSKNQT STGEDVGSFN LVAEVLNQEM FITMSRTLDR AYGDKDWRLL TTVMRCFTQI LLTIQEMASS GNEENEEIAD NILSRLFYEE TTHDLIANIV RTYKDQGFEY LDACTELTHT FVRILEAYSK ENVDLQVRSR KRTRRKKKAA KAAGDQGDDE GQGDAEDDSA DDERQAEKTS QERKFDFKRF ALRFAPQGVV DTFVTFTKYY RDLDDSQLKR AHRYFFKLAF KQDMSVMLFR LDIIHLFYNM IKGPEPLDKS SSMYKEWEDL AMQTIRKCVK KLEERPALFT ELLFSKITST AHYLEYGHEK QTISNPRPAA ELEFKREVER EQQIAILVGV LIDRSQTDHL GWIKKQLSDA ESERRAWENA ERALAAERPD DEVMAGSAEA IAAKTPDHVT MRPDTDARRT AMFKNPHLRL LMKLVGLERL APTLDETPDA IWIIPGTLTA DALKETISLI NKAEFTPPIF DDGELAEDQL RRKTAPRKRA AYDDDDNLDG INDLINDGSD DDGDDGTGIL FPAGGPTARK RTAQDEPPKK RLQRRRRRGG SDDPDADTAE TDAQAEARAR ARRKKELEKA RKIKSEMYVD PREDDSDYEG NKERDRLFFA REEERQAVKD ATFGLSSRPE GVGEGAWEAL VGAVMGGGDG DDGEGEDAVV GERPPKVGGR KRKSGVADLA ESGGEDSEEG DEDDESRSEE DGSAVSEAEA PAAAGRRPNK RRKPAQKKKK RVVDISSGED DDVGMDMDVD VDADADADAM DFTQSSKDGA VTNDTPLSSD PSRTTKPGGA EGSGDKGGGE DEDEDMPVAK PVARARPRAR AGFIVESSDE E // ID TOF1_COCIM Reviewed; 1171 AA. AC Q1DM35; J3K6H1; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 11-JUL-2006, sequence version 1. DT 14-MAY-2014, entry version 33. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=CIMG_08628; OS Coccidioides immitis (strain RS) (Valley fever fungus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Onygenales; mitosporic Onygenales; Coccidioides. OX NCBI_TaxID=246410; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=RS; RX PubMed=19717792; DOI=10.1101/gr.087551.108; RA Sharpton T.J., Stajich J.E., Rounsley S.D., Gardner M.J., RA Wortman J.R., Jordar V.S., Maiti R., Kodira C.D., Neafsey D.E., RA Zeng Q., Hung C.-Y., McMahan C., Muszewska A., Grynberg M., RA Mandel M.A., Kellner E.M., Barker B.M., Galgiani J.N., Orbach M.J., RA Kirkland T.N., Cole G.T., Henn M.R., Birren B.W., Taylor J.W.; RT "Comparative genomic analyses of the human fungal pathogens RT Coccidioides and their relatives."; RL Genome Res. 19:1722-1731(2009). RN [2] RP GENOME REANNOTATION. RC STRAIN=RS; RX PubMed=20516208; DOI=10.1101/gr.103911.109; RA Neafsey D.E., Barker B.M., Sharpton T.J., Stajich J.E., Park D.J., RA Whiston E., Hung C.-Y., McMahan C., White J., Sykes S., Heiman D., RA Young S., Zeng Q., Abouelleil A., Aftuck L., Bessette D., Brown A., RA FitzGerald M., Lui A., Macdonald J.P., Priest M., Orbach M.J., RA Galgiani J.N., Kirkland T.N., Cole G.T., Birren B.W., Henn M.R., RA Taylor J.W., Rounsley S.D.; RT "Population genomic sequencing of Coccidioides fungi reveals recent RT hybridization and transposon control."; RL Genome Res. 20:938-946(2010). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=EAS30169.2; Type=Erroneous gene model prediction; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; GG704913; EAS30169.2; ALT_SEQ; Genomic_DNA. DR RefSeq; XP_001241465.1; XM_001241464.1. DR RefSeq; XP_001241752.1; XM_001241751.1. DR GeneID; 4560065; -. DR GeneID; 4560257; -. DR KEGG; cim:CIMG_08628; -. DR KEGG; cim:CIMG_08915; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1171 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301736. SQ SEQUENCE 1171 AA; 133840 MW; 3E6A7E20D7BAA9B0 CRC64; MEIEPPQAVE VVDPEVRSYV YSLVTALGGT AGNETGRYVL GDDALGCLRD LKKWLRFYDE KLNRMDVARC LAECKLLNGD LVPIISLYGD AEQSDKHKAR IMLACLELLV PLTWPVEVHG QMTFNHHRHT PYLQYSQVEY KRGILGFAPS PILRALIRVG LPSMAIPRSE RSTRDEGIIR LMLYFFRNIA VISSPPNLPI DSDDDKATRS ATINAFQQQD VFALLLTMCS NMGNDFTFQD VIILEILFNL VKGVDVDQLF KLNERAGTIK TDDLQDILQK EDELNREHSK NAPTRHGRFG TMIWVKRDDE KLSTVSGQDV LKGDRATFLK MDKTKKWNKP KFKREVVDPS SNNFNLKVRL TSSATKHLRT FVEEFLDSGF NPLFTHLRKA IEREADRVTE STSRQFWYAV SWFLHAERAR REHQKETRQR SKGTSREIEP DSFSLVASVL NQETFVGLNR FMQHSIDFKD WQDLTAGMKC LTQILLTVQE MAISPLEEDQ EIAENIQSRI FYEETTHDRV LSILRNYKDQ GFWYLDACTE LAHVFLRMLE QYSKQNVDMQ VRSRRRARRK QAQAAVPNQN ETEAGGEHDS DTEDIAEAHQ TVTERSFDFK RFSVRFCTQK SVDTFVALTK YYRELDSEQL KRAHRFFYRV AFKQDMSVLL FRVDIISLLF KMIKGPEGLD PSKPPFKDWE ELIRQIFKKL VRKLGERPEL VVELLFSKIN ATVFYLEYGH EKQTMSESRP ATELELKPGS ASTLDEKIRI VVSALIQEDK KPLVKWLSQV LGSAASERLS WEMEAEARAT SSPQEQSDRS KAPSIAVLPE DDGCRTAMFR NARLRLLMRL AGLERLDEDV LGASWMIPSS VPSSNLKEYH ELIEKHCESP AEDIDGVDPR DLMRRKRTAA DTDSSRHEFT ENVNFGSDSE GEDDGVLFPP NLPERSKALK TLKQRRRRRR RSDDAEESGP DEAVLEARRT AREKNALERQ RKIKSDLYVH ASDDESDEEA DIEFFAKEEM RRQAQARRVA EALETGMPEN NTTKKKSKAS AGRKRKVKPV LELDDDDSEA SPPKRRRSDE VIESDSDGEL MVGIGSTSPR RSQTPPTSAD NIFGSEKSPS PMFPWSVGVD QMMAKLQGKD EASADNGESN EDEGEDVLSG TGRTRRRRTM GGFVIGSDSD S // ID TOF1_CRYNB Reviewed; 1074 AA. AC P0CR93; Q55QA1; Q5KFW4; DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot. DT 28-JUN-2011, sequence version 1. DT 14-MAY-2014, entry version 7. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=CNBF4360; OS Cryptococcus neoformans var. neoformans serotype D (strain B-3501A) OS (Filobasidiella neoformans). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella; OC Filobasidiella/Cryptococcus neoformans species complex. OX NCBI_TaxID=283643; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=B-3501A; RX PubMed=15653466; DOI=10.1126/science.1103773; RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., RA D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., RA Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., RA Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., RA Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., RA Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., RA Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., RA Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., RA Fraser C.M., Hyman R.W.; RT "The genome of the basidiomycetous yeast and human pathogen RT Cryptococcus neoformans."; RL Science 307:1321-1324(2005). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AAEY01000032; EAL20110.1; -; Genomic_DNA. DR RefSeq; XP_774757.1; XM_769664.1. DR GeneID; 4936988; -. DR KEGG; cnb:CNBF4360; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1074 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000410308. SQ SEQUENCE 1074 AA; 122782 MW; CF4047A40F036E41 CRC64; MELPDSPPPL DAPSPPHFLD APQDRWNVFY PAVQTLVNAL GGYEEVESPP DSGIFETVYR PGDSVLGVLK DLKKLWRKDD EDDERTVARC MYRAELMKEL VAIVVECAER GEWGRKVALV ACDLIAALTW PIDVAQELKE IEDEGPVVTD YASLLRAQLE YKALFLKTTK PLKSILSLMV PCLAKPRKDE KDSRIISLGL HVVRNLLAIK DAVAEGTATG EKEEFAHLQS DLITQLDSLT YLQLFLTLAS CADKTDLNPF NVIVLDILHL IFRGIKPSEL VQDQKRVPID SLAKLLEKEK KQKALNSRVG STRHSRFGTT ITVKTAEQRV VLHRQTAIIE NPGKILDMTK RKKAVVAKRM DDLTVFVNLS SDAMVILQSF SKAFLEICYN TFIESILRDI RMERTKIRPS DNIRVFYLSS FFIEYLLLLR HKLLQKGGSR RLEELPLGLV AQIAEMDSVK WLFARLRICW DDKPKAWTEL QACIECFTQI LLLIDDMSTS TNEEDVEVAE ILQHQLYYNY DILDSALAVV REYKNQSIAY LDSIIHFAYV LLRMLEKYSK TKAFMFIRKR KNTHKKRKER QAASQANADR EQRKIPEEYG DEGEEAFAPD EDAPSYAEHA FTFQSFEKRF AQEAVVNTLL TYLERFLEFD GPEPMKRVVG LMHRQVIKAH AEGLYFKVST LIIFRRILDK QHVLPAAPSS RDLITLITYI LRKFFKHVEK EPFTLVEALS SKSRGKWKTV GGGSDDDDDE MAGQRGRIKE KMGPVELQFI KKHKFSWSQQ MSIAFAIIWG DGHGYLIKWI VEVLEQVLAA KQEIVLTTDG GINGDEDEED EDGNARVRRF GRPSDEAISK FTQFDLQPEE SEQITAVTSN PHFRLMLKLL SFDLPPPPME LDFEEDVSSE ELALAREKSD SAWFLPANVL PSDIEASIGA LKQYMEEPPT LDDDPKKLLR RKARATRRRR RSPSVESYDS ETGEVRPGHQ HKKNPRQKRA KKAVETQNYK SAAFIEDSDD EDPEATRRFF ENEERLRREM DELAAQGGHP MMERGVKRKR GKKNGKGAIS DTPPPSQRGN DRET // ID TOF1_CRYNJ Reviewed; 1074 AA. AC P0CR92; Q55QA1; Q5KFW4; DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot. DT 28-JUN-2011, sequence version 1. DT 14-MAY-2014, entry version 9. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=CNF00340; OS Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / OS ATCC MYA-565) (Filobasidiella neoformans). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; OC Tremellomycetes; Tremellales; Tremellaceae; Filobasidiella; OC Filobasidiella/Cryptococcus neoformans species complex. OX NCBI_TaxID=214684; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=JEC21 / ATCC MYA-565; RX PubMed=15653466; DOI=10.1126/science.1103773; RA Loftus B.J., Fung E., Roncaglia P., Rowley D., Amedeo P., Bruno D., RA Vamathevan J., Miranda M., Anderson I.J., Fraser J.A., Allen J.E., RA Bosdet I.E., Brent M.R., Chiu R., Doering T.L., Donlin M.J., RA D'Souza C.A., Fox D.S., Grinberg V., Fu J., Fukushima M., Haas B.J., RA Huang J.C., Janbon G., Jones S.J.M., Koo H.L., Krzywinski M.I., RA Kwon-Chung K.J., Lengeler K.B., Maiti R., Marra M.A., Marra R.E., RA Mathewson C.A., Mitchell T.G., Pertea M., Riggs F.R., Salzberg S.L., RA Schein J.E., Shvartsbeyn A., Shin H., Shumway M., Specht C.A., RA Suh B.B., Tenney A., Utterback T.R., Wickes B.L., Wortman J.R., RA Wye N.H., Kronstad J.W., Lodge J.K., Heitman J., Davis R.W., RA Fraser C.M., Hyman R.W.; RT "The genome of the basidiomycetous yeast and human pathogen RT Cryptococcus neoformans."; RL Science 307:1321-1324(2005). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=AAW44173.1; Type=Erroneous gene model prediction; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AE017346; AAW44173.1; ALT_SEQ; Genomic_DNA. DR RefSeq; XP_571480.1; XM_571480.1. DR UniGene; Fne.904; -. DR EnsemblFungi; AAW44173; AAW44173; CNF00340. DR GeneID; 3258248; -. DR KEGG; cne:CNF00340; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1074 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301737. SQ SEQUENCE 1074 AA; 122827 MW; 4BD986B764BDC664 CRC64; MELPDSPPPL DAPSPPHFLD APQDRWNVFY PAVQTLVNAL GGYEEVESPP DSGIFETVYR PGDSVLGVLK DLKKLWRKDD EDDERTVARC MYRAELMKEL VAIVVECAER GEWGRKVALV ACDLIAALTW PIDVAQELKE IEDEGPVVTD YASLLRAQLE YKALFLKTTK PLKSILSLMV PCLAKPRKDE KDSRIISLGL HVVRNLLAIK DAVAEGTATG EKEEFAHLQS DLITQLDSLT YLQLFLTLAS CADKTDLNPF NVIVLDILHL IFRGIKPSEL VQDQKRVPID SLARLLEKEK KQKALNSRVG STRHSRFGTT ITVKTAEQRV VLHRQTAIIE NPGKILDMTK RKKAVVAKRM DDLTVFVNLS SDAMVILQSF SKSFLEICYN TFIESILRDI RMERTKIRPS DNIRVFYLSS FFIEYLLLLR HKLLEKGGSR RLEELPLGLV AQIAEMDSVK WLFARLRICW DDKPKAWTEL QACIECFTQI LLLIDDMSTS TNEEDVEVAE ILQHQLYYNY DILDSALAVV REYKNQSIAY LDSIIHFAYV LLRMLEKYSK TKAFMFIRKR KNTHKKRKER QAASQANADR EQRKIPEEYG DEGEEAFAPD EDAPSYAEHA FTFQSFEKRF AQEAVVNTLL TYLERFLEFD GPEPMKRVVG LMHRQVIKAH AEGLYFKVST LIIFRRILDK QHVLPAAPSS RDLITLITYI LRKFFKHVEK EPFTLVEALS SKSRGKWKTV GGGSDDDDDE MAGQRGRIKE KMGPVELQFI KKHKFSWSQQ MSIAFAIIWG DGHGYLIKWI VEVLEQVLAA KQEIVLTTDG GINGDEDEED EDGNARVRRF GRPSDEAISK FTQFDLQPEE SEQITAVTSN PHFRLMLKLL SFDLPPPPME LDFEEDVSSE ELALAREKSD SAWFLPANVL PSDIEASIGA LKQYMEEPPT LDDDPKKLLR RKARATRRRR RSPSVESYDS ETGEVRPGHQ HKKNPRQKRA KKAVETQNYK SAAFIEDSDD EDPEATRRFF ENEERLRREM DELAAQGGHP MMERGVKRKR GKKNGKGAIS DTPPPSQRGN DRET // ID TOF1_DEBHA Reviewed; 1299 AA. AC Q6BPI8; B5RU06; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 16-DEC-2008, sequence version 2. DT 14-MAY-2014, entry version 46. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=DEHA2E13288g; OS Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC OS 0083 / IGC 2968) (Yeast) (Torulaspora hansenii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Debaryomyces. OX NCBI_TaxID=284592; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., RA Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., RA Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., RA Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., RA Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., RA Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., RA Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., RA Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., RA Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., RA Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., RA Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., RA Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., RA Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CR382137; CAR65818.1; -; Genomic_DNA. DR RefSeq; XP_002770475.1; XM_002770429.1. DR GeneID; 8998743; -. DR KEGG; dha:DEHA2E13288g; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000094158; -. DR KO; K10997; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1299 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301738. SQ SEQUENCE 1299 AA; 149139 MW; 77B5A6AEA311F663 CRC64; MSRSGSEEER FSSDEGMEEL GDFIVSDEEP NHESARDDDA EVHNDRLLQM TSTLKPNESQ TQKLLRAHIS VLVSALGGPD HTSPISPPPY KLGQDALACL KDIKRWIKSV DEKKGNFDVA LACADSGLVV NDLLVILCQW DSQQNSKKPL KNARTMEKIM LSCLELLVLL TWPTDLNSES SENQKLHFAS VRKSQIVYKK HILAYNKGQT LKAVIRLVLP TIAKHRIDRE PRDNAILRLV LFFIRNVLNI EPANSSISTK SRKHVTNLDN LPTNVNYDDI SMNAVLSCFK NNKVLMFLLT LSGSLGTDFD KETFGQPCLE CIYLIIKGVK TQDILNPQQN SKQQQRYQQQ QREQSQQDQN PIQSVTTTSG LELQDLLSEE SKRKKFQTQN ISTRHGRFGS LLSIQGNNTS YVISGQEALL DTNSSLAKLD ESKKWNNRSH FKYDSDDYVK ATSEFLNGSS VIILKEFIEQ FLSGGCFNTL IECIGWLLSG TNDLNYVDDY EKACYFLTVA WFLNYKRERN VLFDILGTAN LDEDDDGLDY GSVSAGLSEV NFILIISYFR ESFEAKNWNS LHVAMICFKE LLLISYSIFS RFSDRGLQGE EEADDDQEEI DKELAEGIIR KLFSFNDFLN IVIQIPQTAS KHSPEYLSVC ISVVHIILKS FESFANENIK LYIQTKRKRT KQNKKSINTL DKATEESLRD VIEGSDDELE NERVKEVSRE RRLDFKVTEV RFFQTSIVST YVEYLSRYEE LTHEEIKRCL SYFHRLFVIR KDFTGLYRMD FMYILQKLRS YLPKGSSTRD HVDEFIYYFM KKFKNAFERF PNPVEILFPR FEDMEYKIFL ATGDLYLKPE KNNKRSSVKI AKNIEFIRDN FSLDEKLKIL VTVLYIQEKE SLVTWVIQEL TKITTNRLMN LSSEQIESNT NEAVQLYPLE QHRRLLINNP YIRLLLTLVG FKVPFILEEP CELPDNVETS NLTECLDSIK MWSNKQPVTF DDGKDAMFFL RTKEGYNYEQ DDDYDGHYDE NDESIAFETG ANPDGERHNL NELDELDKLE AALEGKSNKD TDLPRGVARI KNKKPKKDLP KKSKANSRKK HLSRRPPKSF KVVSDGEEEK QEKTKSAEFV HGSDDESDYE KENEFFDREE RLRRLLEESG GIVNPKQLAE FKVSWSKLES SNGTDTAISV SKAIENTSFV EDTMPHTQNI PEELTLGAIN ESNSDIDTSS DSEPELNGSG AESVSAIEND KTSVSSFTPD IHNETSSKKR HIILQDRDSE DEVDITTGNH EIKASNPRKR RVVISDDEE // ID TOF1_EMENI Reviewed; 1167 AA. AC Q5AXH3; C8VC91; Q9Y8F5; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 11-SEP-2007, sequence version 2. DT 14-MAY-2014, entry version 42. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; Synonyms=mdrA; ORFNames=AN7007; OS Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL OS 194 / M139) (Aspergillus nidulans). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Aspergillus. OX NCBI_TaxID=227321; RN [1] RP NUCLEOTIDE SEQUENCE [GENOMIC DNA]. RA Cheong C., Kang H.-S.; RT "Cloning, sequencing, and functional analysis of mdrA, an Aspergillus RT nidulans drug resistance gene."; RL Submitted (JUN-1998) to the EMBL/GenBank/DDBJ databases. RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139; RX PubMed=16372000; DOI=10.1038/nature04341; RA Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., RA Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., RA Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., RA Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C., RA Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., RA Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., RA Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., RA Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., RA Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., RA Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.; RT "Sequencing of Aspergillus nidulans and comparative analysis with A. RT fumigatus and A. oryzae."; RL Nature 438:1105-1115(2005). RN [3] RP GENOME REANNOTATION. RC STRAIN=FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139; RX PubMed=19146970; DOI=10.1016/j.fgb.2008.12.003; RA Wortman J.R., Gilsenan J.M., Joardar V., Deegan J., Clutterbuck J., RA Andersen M.R., Archer D., Bencina M., Braus G., Coutinho P., RA von Dohren H., Doonan J., Driessen A.J., Durek P., Espeso E., RA Fekete E., Flipphi M., Estrada C.G., Geysens S., Goldman G., RA de Groot P.W., Hansen K., Harris S.D., Heinekamp T., Helmstaedt K., RA Henrissat B., Hofmann G., Homan T., Horio T., Horiuchi H., James S., RA Jones M., Karaffa L., Karanyi Z., Kato M., Keller N., Kelly D.E., RA Kiel J.A., Kim J.M., van der Klei I.J., Klis F.M., Kovalchuk A., RA Krasevec N., Kubicek C.P., Liu B., Maccabe A., Meyer V., Mirabito P., RA Miskei M., Mos M., Mullins J., Nelson D.R., Nielsen J., Oakley B.R., RA Osmani S.A., Pakula T., Paszewski A., Paulsen I., Pilsyk S., Pocsi I., RA Punt P.J., Ram A.F., Ren Q., Robellet X., Robson G., Seiboth B., RA van Solingen P., Specht T., Sun J., Taheri-Talesh N., Takeshita N., RA Ussery D., vanKuyk P.A., Visser H., van de Vondervoort P.J., RA de Vries R.P., Walton J., Xiang X., Xiong Y., Zeng A.P., Brandt B.W., RA Cornell M.J., van den Hondel C.A., Visser J., Oliver S.G., Turner G.; RT "The 2008 update of the Aspergillus nidulans genome annotation: a RT community effort."; RL Fungal Genet. Biol. 46:S2-13(2009). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=AAD41625.1; Type=Erroneous gene model prediction; CC Sequence=CBF79271.1; Type=Erroneous gene model prediction; CC Sequence=EAA61653.1; Type=Erroneous gene model prediction; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AF072683; AAD41625.1; ALT_SEQ; Genomic_DNA. DR EMBL; AACD01000117; EAA61653.1; ALT_SEQ; Genomic_DNA. DR EMBL; BN001304; CBF79271.1; ALT_SEQ; Genomic_DNA. DR RefSeq; XP_664611.1; XM_659519.1. DR STRING; 162425.CADANIAP00000469; -. DR EnsemblFungi; CADANIAT00000469; CADANIAP00000469; CADANIAG00000469. DR GeneID; 2870083; -. DR KEGG; ani:AN7007.2; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 3. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1167 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301739. FT CONFLICT 635 635 E -> V (in Ref. 1; AAD41625). FT CONFLICT 1016 1016 L -> C (in Ref. 1; AAD41625). SQ SEQUENCE 1167 AA; 134367 MW; 3234327D27F1BA6A CRC64; MEEAVPAQTV EVIDPEVRAH VYSLLGGFNG EDADKYVLGD DALSCLRDIK RWLKLYDEKF NRMDVARCLG EANLVNGDLI QILSLWWREG QQSKYMTRIA LACVELLVPL TWPLEIHGEM TVNHHRHIPY LQQAQVGYKR GILNMASCGI LRAVIRIGLP SMAIPPSERT ARDEGILKIM LYLLRNIAII TANARLAAEG EEEETSRSAT INAFHDQDVF ALLLTLCSNV SDDFNMLDIP LLEILFHMVR GIDVEKLFMN DAQRSAKRTD ELNDLLRQES SMRREYAKNA PTRHGRFGTM IWVKRDDAKM STVSGQDVLR DEQTTLYKMD QSKRWNKPRR GRKAQDMSVN NDFNTPVHIS PSATTNLRMF VEEFLDSGFN PLFVHVRKAI ERESIRVLDI NKRHFLYTVS WFLGAERARR ARQREKYAQS GKKPDNELEP DSFGLVAGVL NQETFVFLNR SMQNSLDNKE WDDLNAAMRC FTQILLTVQE MSQSPLEEDQ EIAENIQNRI FYEETTHDRI LAILRGYTDQ GFGYLDACTE LSHVFLRMLE RYSKTNVDMQ VRSRRRARKR KREEQLVNKG SDEEQESEDE DYAEAEKMSK ERKFDFTRFA AKFSNQKCVD TFVAFTKFYK ELNNEQLKRA HRYFYRIAFK QEMTVLLFRV DILNLFYRII KGPGGMDSSK PIYKEWEELV RQLIRRLIKK LEQRPALITE LLFSKINSTA FYLEYGFEKQ TVTTSKRAPA ELEVDPKAAS TPEEKLSIVV AALVKDEQSA LVKWISEVLG SAADEREAWE LNSHDVDLAG PRDTQNPIIT VKSQDNSFKR AMFQNAKLRL LMTLLKFDRL GQENVEGISW IIPSELKSDE LRESKAVIDK ALLIGNTDER DPNDLLRKKY SHEPRDGFSG QNLDVNFGSD SEGEDVIPDG PLFPANPRSK AHALNELKQK RKKRKDKGEE EPVDEETLEE RRQARLENTR WRLAKIKSDL YVHASDEESD AEADQEFFRL EEERRNEQSE RIKKALLLGR TEDAGNKARQ RKRGKRSNEP NIAGEEETSG KRRRHSGGTN VELEEDDILM DDMEMPSRAS SGEYSSNDAD AIDKSMAAAE DELYFDDDLA FGRDRDKDET SVDRDGADAS SPRKHNDGSE SAEEDIPLAP PNRRRLRAGF VVESDSE // ID TOF1_KLULA Reviewed; 1162 AA. AC Q6CUU2; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 16-AUG-2004, sequence version 1. DT 14-MAY-2014, entry version 46. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=KLLA0C02255g; OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC OS 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Kluyveromyces. OX NCBI_TaxID=284590; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / RC WM37; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., RA Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., RA Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., RA Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., RA Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., RA Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., RA Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., RA Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., RA Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., RA Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., RA Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., RA Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., RA Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CR382123; CAH01148.1; -; Genomic_DNA. DR RefSeq; XP_452297.1; XM_452297.1. DR STRING; 28985.Q6CUU2; -. DR GeneID; 2892434; -. DR KEGG; kla:KLLA0C02255g; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1162 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301740. SQ SEQUENCE 1162 AA; 133245 MW; CAE919C2B95A19EA CRC64; MSEPDDVDTV KERLAEDRQN IHIQNEYQDI SYTIIKARIG MLATAIGGPD HSVDSVNPPY KVGDDCLACI KDLIRWFKLV DDNQKRWDVE MATAEFKILQ NDLIPILLDW EAKNSAATRK SKKTGEDISI FFPNKSYHDR IALGALQLMV LMTWPLIITD QSSYNQVNYY FELKKHQLLY KHAILTTENG KVLKAAIRLA LNVMSVDVDH RTARDDSLIR MVLNFLKNVV AIEPGEVTIS SVKRLKRPLT MAEMLPTNIT VDDISINSVI TAFDKNKVFG FLLTVASSLS DAVDPNFVSW PLLEVMFFLT KDINPIRLFK NQRKSYKLGT DHEITDSNMT TSGKHLSELL AKEHEKKLNV IKNTSSRHSR FGGLLSIQTP QNTRLTIASN SVNMRDDAAL QELDSRKKWN KTITMRLDVI EGLSSSFFST EGNSIYMSSD NITSIKEFLA DFVDSSFNLL LQNATDSFTS EIQDQLPLHK IEYMLFISWF VKFQRSRCIY EIDATPDYVS GALLDECYIL FTKYLRESYE QKNWPVVHAG MLLFTEYLEF LLSLDQSWEA DVQAVISKIL SENMLQLLAS LPKSATSHSS QYVKACINLT HVVLKTIDKF DENSSLTVES KRKRKVNLNH TAIEKYAKDN DLDYESAFDI LEEQFKQVTI NFDKVFRGYL TEPTISTYIR YLQSYKELED KDLIRVLKFF QRVFVKAKEE LFLFRIDFMI LCREILSQQG LPTTSELRTH FTKFNEYYLK QLKNKLKKMP SLYINILFPM LHDSQISYYM RHGKMKLTEG TPDIVLPSTF INIPDEGSLP KKVLLDMQVG ILVSSLIDDG YEDLIEALLL NLQSSFDGLK GKVAEGINSL EEERVKKVAF NATNSEIKRA LYQQPEFRRL LILAGFAIPE ANQPACYFIN NKTPTEVQLV IETIQKHRSL PFESEIGKPA SYYLSSHYQE YEDPEEYGSD LNNGSYFEDL EIMDKRTEGR ELSKGKAQSK LVQRSKGKRK AIAHHPEENE SDFEANASSS TKLPVVSKEY IMDSDDEDPD FGAIFFENET YLRQLLDKHN GSLTETQFSL FAQFCEERVK NNGQLRNDYS ALFNETPKSP IFSDVDAETI IIGSASLPSL ANEPIETQVV SSEEYSSHPL EEEVTSEQRK RKKPRIESDT EY // ID TOF1_LODEL Reviewed; 1175 AA. AC A5E2H7; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 11-SEP-2007, sequence version 2. DT 14-MAY-2014, entry version 23. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=LELG_03814; OS Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / OS NBRC 1676 / NRRL YB-4239) (Yeast) (Saccharomyces elongisporus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Lodderomyces. OX NCBI_TaxID=379508; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC -!- SEQUENCE CAUTION: CC Sequence=EDK45635.1; Type=Frameshift; Positions=41; CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH981528; EDK45635.1; ALT_FRAME; Genomic_DNA. DR RefSeq; XP_001524782.1; XM_001524732.1. DR STRING; 36914.A5E2H7; -. DR GeneID; 5232181; -. DR KEGG; lel:LELG_03814; -. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1175 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301741. SQ SEQUENCE 1175 AA; 134406 MW; A8944BAD44198CBE CRC64; MEEDKIRALT TTLKPNETQA QKLLKAHIAV LVSALGGIDK TSEIVPPPYK LGHDALACLK DIKRWIRAVD ERQHNYEVAL ACAESGLVQN DLIIILCQWD SQMQNKKQKT DTMVRNKTAM EKIMLSCLEI LVLLTWPMEF GTNLSENQKL LFAQVRKIQV LHKKHILTYN DGQVLKAVIR LALPVIAKTR IDREPRDNQI LRLVLYFTRN LLAIEPENDS ISTKTNNKRA TPSSNLPNGV SPDDISINNL LRVFKKNKVL MLLLTITGSI NSEFEKDLFN EICLESVYLL IKGLEAKDVL VNKPTSTTKM NTKTAAAAAT TATTATTTTT NTTSSVDISA TTPLQPLSST VGLQLQDLLN TEAKKRQSQK QHIATRHGKF GTLLSIRSAD ANSYVVSGEE ALINSNGTMD KLDKSKTWKM KNHFTYDSDE FVKTNSPIYL NAQGRQILSY FIEEFLSGGC FNNLIESMTS KLTSQLEYSL IDELTQASYF YTIAWFLNYQ REQITLSGLQ TFDFGVVRAA LSEVNFILIV AYFRDSHQKR LWNSLHVAMI CFKELLHISN SIFGKKRART TNDDTIGDDE QYEIDRELAE GIIRKLFSFN EFLNTLVQVP QIAYKHSPRF LAESIRVITI ILKSFESFAK EDLQLYVQTK RRRNKKKQQR INELDRDTES KLSTAIYESD EELAQENLRE VTRERKLNFQ ATEVRFFHQN VVTTYIEYMS RFEDLTHEDI KMCLTYFHKL FVVRKDYNGL FRLDFMQLIY KLRNHLPKGS PIRLKVDEFI YYFMKKFKLA ITRFPNPLEI LFPRFEETRF KHYLSTGELY QLDTAVDPRA IRNLNKEVID NDYNDAVDND NNNDNYNEDD EDGIAFEIEA NPEAADNHAY DLDRLDELES QLTNYQSRNK NRSSLEKGIA KKRNSRKKST KTSKVNSDGG DSDDDDDDAD AAAAAKAHRK RRVPRDLLFE EPKPLRSAEF INDSDDESDD EKNAEFFARE ERLRQLLNQT GNITDAQKLE EFKKVWQQYS KTGGSIMQDA VANAVKEVSL FISDGDDDDD DGNGNENQKG KRKRTRDEAD DFDGVSTILD SVQSQVLDNG SSQGNFASDA EVYHASSNTS DTELETNKRA KIDDAEEKED EGKGEKEEDD NADEDEDEDE DVDGEESFPV VHHKKKRAII SDDEE // ID TOF1_MAGO7 Reviewed; 1214 AA. AC A4R4R3; G4NGY5; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 15-MAY-2007, sequence version 1. DT 14-MAY-2014, entry version 40. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=MGG_03991; OS Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice OS blast fungus) (Pyricularia oryzae). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Magnaporthales; Magnaporthaceae; OC Magnaporthe. OX NCBI_TaxID=242507; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=70-15 / ATCC MYA-4617 / FGSC 8958; RX PubMed=15846337; DOI=10.1038/nature03449; RA Dean R.A., Talbot N.J., Ebbole D.J., Farman M.L., Mitchell T.K., RA Orbach M.J., Thon M.R., Kulkarni R., Xu J.-R., Pan H., Read N.D., RA Lee Y.-H., Carbone I., Brown D., Oh Y.Y., Donofrio N., Jeong J.S., RA Soanes D.M., Djonovic S., Kolomiets E., Rehmeyer C., Li W., RA Harding M., Kim S., Lebrun M.-H., Bohnert H., Coughlan S., Butler J., RA Calvo S.E., Ma L.-J., Nicol R., Purcell S., Nusbaum C., Galagan J.E., RA Birren B.W.; RT "The genome sequence of the rice blast fungus Magnaporthe grisea."; RL Nature 434:980-986(2005). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CM001236; EHA47495.1; -; Genomic_DNA. DR RefSeq; XP_003719862.1; XM_003719814.1. DR STRING; 148305.A4R4R3; -. DR EnsemblFungi; MGG_03991T0; MGG_03991T0; MGG_03991. DR GeneID; 2677242; -. DR KEGG; mgr:MGG_03991; -. DR eggNOG; NOG328380; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1214 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301742. SQ SEQUENCE 1214 AA; 137298 MW; 5F5773B876F1E443 CRC64; MEASDGSNDV VHPEVRAHIN SLVSALGGFS ADDDGRYKLG DDALEVLRDM KKWIRFYDEK TNRMDVARCL SEANVVGGDL LQILATWPEA QSDSKFKARV ALACYEIMTP LTWPIEKDPE RTTVNHYRHM PVLQLAQLGY KRDIINFDGA QILHTAIRVA LPSMAVPIGD RTPRDQGIIK LVLYFLRNIA MIAPPPGLKY DGDESQISRS ATIDAFSYQD IFLAILTIAS NMGEDFRTED VIIMEIIFHL VKRVDIRKLF LDGEALSKAK GEDLVALIKK EKSMLRAQNK RAPTRHNRFG TMVWVQRADG RMSAISGQDA LRDSATRERK MDDSKTFRPP RRSRKAEMEP KDLGSPVSLN ERANKQLRGF VEEFLDSGFN PLFQHIRKTI DREAPYLLHQ HRAQFFYLTA WFLQAERERI KTAKNQGSST TQDDVSPFNL VAGVLNQEMF ITLSRAMDRA YNDKDWPELT TVMRCFSQIL LTVQDMADSG DEENEDIAEN ILNRLFYEEA THDAIANIAR NFKDQGFEYL DACTELIHTY LRILESYSKQ NVDMQVRSRK RTRKKKKAAK ATGEDGDPVD DTRIDDGDDS ANDEASAERT SRERKFDFGR FAMRFVPQGV VDTFVQFTKY YRDLDDSQLK RAHRYFFRVA FKQDMSVMLF RVDIIHLLYN MIKGPEALDK SSSMFKDWEE LVKQIIRKCV RKIEDRPALI IEMLFSKINS TAHYLEFGFE KQTISGSANP RPGAELEFKK QDLNLEQQIA IAVGVLLDKN QADHLTWVKN VLSNAEVERR AWETAQDALP SVESQNVEGD IENEAPAASS IPQDSTPTIV RPDHDGRRGA MFKNPHLRLL MRLVGFERLA PSEAETPESA WIIPANLRAD QLQEAVGHIN AAEFNPPVFD DDKSAEDQLR RKSAGTTSRR KKAAFDDDEE NDVDNEDDDG LEEFLFEPGG PTARKSDVRP KKKLTRRKRS PGQELTDEQQ DEKARLRREK DLEKQRKIKS AARVHSSDEE SDQEADAAFF AREKERMAAR NALYSRLARN PGEFAAEKAA GKTTKVPVLL SDESGGEDSV AAAERSKRRK RKSESVAGDE DDRDGGSDGG SEDAGTPARD APETKPLPKR RKKATAFVVS SDEEDSGDEA PANTRGQSSQ RSAAEDAMET DETPLSSSPH KTKTTDVEMA NDDDHDEEDT PVKAPTQRRP RAKAGFVLDS SDEE // ID TOF1_NEOFI Reviewed; 1177 AA. AC A1D9I5; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 23-JAN-2007, sequence version 1. DT 14-MAY-2014, entry version 32. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof1; ORFNames=NFIA_028970; OS Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL OS 181) (Aspergillus fischerianus). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Neosartorya. OX NCBI_TaxID=331117; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 1020 / DSM 3700 / FGSC A1164 / NRRL 181; RX PubMed=18404212; DOI=10.1371/journal.pgen.1000046; RA Fedorova N.D., Khaldi N., Joardar V.S., Maiti R., Amedeo P., RA Anderson M.J., Crabtree J., Silva J.C., Badger J.H., Albarraq A., RA Angiuoli S., Bussey H., Bowyer P., Cotty P.J., Dyer P.S., Egan A., RA Galens K., Fraser-Liggett C.M., Haas B.J., Inman J.M., Kent R., RA Lemieux S., Malavazi I., Orvis J., Roemer T., Ronning C.M., RA Sundaram J.P., Sutton G., Turner G., Venter J.C., White O.R., RA Whitty B.R., Youngman P., Wolfe K.H., Goldman G.H., Wortman J.R., RA Jiang B., Denning D.W., Nierman W.C.; RT "Genomic islands in the pathogenic filamentous fungus Aspergillus RT fumigatus."; RL PLoS Genet. 4:E1000046-E1000046(2008). CC -!- FUNCTION: Forms a fork protection complex (FPC) with csm3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of tof1 and csm3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; DS027693; EAW20466.1; -; Genomic_DNA. DR RefSeq; XP_001262363.1; XM_001262362.1. DR STRING; 36630.CADNFIAP00002719; -. DR EnsemblFungi; CADNFIAT00002796; CADNFIAP00002719; CADNFIAG00002796. DR GeneID; 4589179; -. DR KEGG; nfi:NFIA_028970; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 2. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1177 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301743. SQ SEQUENCE 1177 AA; 134953 MW; F98C8138F7947ACC CRC64; MDEEGAPLSE SVQVVDPDVR AHVYSLVTAL GGFNGESADR YVLGDDALAC LRDIKRWLKL YDEKNNRMDV ARCLGEANLV NGDLLPILTL WSTSGQKSKH MSRIALACLE LLVPLTWPLE VPSKMTVNHH RHTPYLQQAQ VLYKRGILSH GSDSILRTII RIGLPSMAVP RSERTTRDEG ILKLMLYFLR NIAVISPNAR LAAEGDEEET SRSATINAFQ NQDAFALLLT MCSNVGEDFS LQDVVLLEIL FHIVKGVNVE KLFMNDAQRK AKRTDELGEL LQKESSLRRE YAKNAPTRHG RFGTMIWVKR DDAKVSTVSG QDVLKDSQTT LHKMDQSKKW NKPQIRRRAA EVTANNDFNT PVNLNSTATK NLRMFVEEFL DSGFNPLFTH VRKAIEREAD RVLDINTRQF FYTVAWFLEA ERVRRAHQRE KRHLGDKSLN EIEPDSFALV ASVLNQETFV FLNRSMQYSY DNKDVEDLTA EMRCFTQILL TVQEMAQSPL EEDQEIADNI QNRIFYEETT HDRIIAIVRG YKDQGFGYLD ACTELAHVFL KMLEHYSKEN VDMHIRSRRR AKRKAKQAKQ ADIEGDDEEQ ASEEEDLMDA ERISKERKFD FKRFAAKFCN QSCVDTFIAF TKYYKELNVD QLKRAHRYFY RIAFKQEMSV LLFRLDIINL FYRMIKGPGA LDSNKPIFKE WEELVRQIIR RMVKKIDQRP ALITELLFSK INSTVFYLEY GHEKQTISAS KRPPAELEVD PREAKTTDEK IKIVVHVMVK DEHTDLVKWV SDVLNSAADE REAWESQEQH SEGQKAPNPM IPVKSNNESC QKAMFSNAKL RLLMTLVRFE RLGMEDVPGA SWIVPSSLTS QDLRHTRSMI EQCLTEPVTE SSDRDLSQLI RRKSGNNTRR DRDDQTADVD FGSDSEGDDN VPDGPLFPPN PRSRASALEQ LKKQRKKRRK QAGEEEEPDE EDLEGRRRAR LENALARQAK IKSDLYIHAS DEQTDEEADQ EFFRLEEQRR KEQAERIRKA LLHGVVEEAS ENSRKKGSGR KRQSDQHTAS TADSQSKRQR RQQRTGGLDD DDDLVMTGTD ARSPDSLGQG SPSLQGANDV EDTPVTSEEN ELDFDDDLAF SRNRNRDKVL SAENDDSDTE PPAPDTIDED DDDEAAPVAA PPRRRMRAGF VIESDSE // ID TOF1_NEUCR Reviewed; 1235 AA. AC Q7S2A9; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 15-DEC-2003, sequence version 1. DT 14-MAY-2014, entry version 55. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=tof-1; ORFNames=B11E5.220, NCU09552; OS Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM OS 1257 / FGSC 987). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Sordariomycetes; Sordariomycetidae; Sordariales; Sordariaceae; OC Neurospora. OX NCBI_TaxID=367110; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987; RX PubMed=12655011; DOI=10.1093/nar/gkg293; RA Mannhaupt G., Montrone C., Haase D., Mewes H.-W., Aign V., RA Hoheisel J.D., Fartmann B., Nyakatura G., Kempken F., Maier J., RA Schulte U.; RT "What's in the genome of a filamentous fungus? Analysis of the RT Neurospora genome sequence."; RL Nucleic Acids Res. 31:1944-1954(2003). RN [2] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987; RX PubMed=12712197; DOI=10.1038/nature01554; RA Galagan J.E., Calvo S.E., Borkovich K.A., Selker E.U., Read N.D., RA Jaffe D.B., FitzHugh W., Ma L.-J., Smirnov S., Purcell S., Rehman B., RA Elkins T., Engels R., Wang S., Nielsen C.B., Butler J., Endrizzi M., RA Qui D., Ianakiev P., Bell-Pedersen D., Nelson M.A., RA Werner-Washburne M., Selitrennikoff C.P., Kinsey J.A., Braun E.L., RA Zelter A., Schulte U., Kothe G.O., Jedd G., Mewes H.-W., Staben C., RA Marcotte E., Greenberg D., Roy A., Foley K., Naylor J., RA Stange-Thomann N., Barrett R., Gnerre S., Kamal M., Kamvysselis M., RA Mauceli E.W., Bielke C., Rudd S., Frishman D., Krystofova S., RA Rasmussen C., Metzenberg R.L., Perkins D.D., Kroken S., Cogoni C., RA Macino G., Catcheside D.E.A., Li W., Pratt R.J., Osmani S.A., RA DeSouza C.P.C., Glass N.L., Orbach M.J., Berglund J.A., Voelker R., RA Yarden O., Plamann M., Seiler S., Dunlap J.C., Radford A., Aramayo R., RA Natvig D.O., Alex L.A., Mannhaupt G., Ebbole D.J., Freitag M., RA Paulsen I., Sachs M.S., Lander E.S., Nusbaum C., Birren B.W.; RT "The genome sequence of the filamentous fungus Neurospora crassa."; RL Nature 422:859-868(2003). CC -!- FUNCTION: Forms a fork protection complex (FPC) with csm-3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of tof-1 and csm-3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; BX842620; CAE76157.1; -; Genomic_DNA. DR EMBL; CM002240; EAA29535.1; -; Genomic_DNA. DR RefSeq; XP_958771.1; XM_953678.1. DR UniGene; Ncr.25426; -. DR STRING; 5141.NCU09552.1; -. DR EnsemblFungi; EFNCRT00000007626; EFNCRP00000007616; EFNCRG00000007614. DR GeneID; 3874918; -. DR KEGG; ncr:NCU09552; -. DR eggNOG; NOG328380; -. DR HOGENOM; HOG000048676; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR016024; ARM-type_fold. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. DR SUPFAM; SSF48371; SSF48371; 4. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1235 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301744. SQ SEQUENCE 1235 AA; 140517 MW; 433E3344D9F4974E CRC64; MEAADINDDV VHPEVRAHIT NLVSALGGYS ADDDGSYKLG DEALDVLRDL KKWIRFYDEK TNRMDVARCL AEANLVGGDL LQILTLWPQS ETDSKYKARI ALACFEVMVP LTWPIEKERA EMTINHHRHM PVLQLAQLGY KRAIINFDAI PILNTAVRVA LPSMAMPIGE RTPRDQAIIK LILFFLRNVA MIAPPQGVKC EGDETQVSRS ATIDAFSYQD IFLTLLTLAS NMGEDFRTED VVIMEIIFHL VKRVDPSSLF VSEKQLNKAK GQELASEMRK EAAMLKSYNK TTTTRHSRFG TMIWVKRADG KMVTVSGQEA LLDAKTRERK MDNSKTFRPP RRARKPEMEP KDLGPPVTLD ERARQQLRSF VQDFLDSGFN PLFLHVRQSI DREALHALNQ HKSQFFYLVA WFLEAERMRR KAKRDESKST SAAGEEVNSF NLVAAVLQQE MFASMNRALD RSYSDKDWQL LTSVMRCYTQ IFLTVQEMSE SPNEEDQEIA ENTLSRLFYE ETTHDLIANI ARTYKDQGFE YLDAATELVH TFLRILEGYS KQNVDLQVRS RKRARRKKKA AKAAAAVAAA RAAGEEAEDV GVPEDNDADD SGDDEQHAER VTQERKFEFG KFAIRFAPQG VVDTFVAFTK FYRDLNDAQL KRAHRYFYRV AFKLELSIML FRLDIINLFY NMVQGPEPLD KSSPMFKEWE ELSKQIIRKC VKKLQERPAL FTELLFSKIG STTHFLEHGY EKPVTTTTPR PGAELEFKRA TERDEQIGIA VSVLIDKQQV EHLQWLKDQL TSAMSERQAW ENVDKAMAAT TEGAADGEAA DERSNKSAPP HITIRPDTEA RRTAMFKNPH LRLLMRLVGM ERLTPTLDET PDSTWILPGS HTAEAIQDTI DLINKAEFSP PTFEDGGSAE DQLRRKSAAA SRRTRAAYDD DEEEIRGFLG DDDDEDFLFA PGGPTARKPD ARPQKKRQRK RRREAGSGDE EDEGVSDEVL AARAKKRREK ELEKIRKIKS EMYVHASDDE TDDERDREFF ERERKRQETK DSKFDSMLGA LGLSVLSQVN GGEKSAWEAV LDDEPESDES ENEGRKNAKR RKKQVASGSE EEQEEEEEEE EEEDSDEELP TKQAKSKTSK RKAAVPSKRP ARRPGTAKKR AVVELSDNDE DEDEEEDAMD VDSANERTTR NEAPLPSSPG EGLGRRIDKM AMDDGDEDED DQPVVAARQR PKARGGFIID SSDEE // ID TOF1_PHANO Reviewed; 1177 AA. AC Q0UJF3; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 05-SEP-2006, sequence version 1. DT 14-MAY-2014, entry version 35. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=SNOG_08111; OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) OS (Glume blotch fungus) (Septoria nodorum). OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; OC Dothideomycetes; Pleosporomycetidae; Pleosporales; Pleosporineae; OC Phaeosphaeriaceae; Parastagonospora. OX NCBI_TaxID=321614; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173; RX PubMed=18024570; DOI=10.1105/tpc.107.052829; RA Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L., RA Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E., RA Torriani S.F.F., McDonald B.A., Oliver R.P.; RT "Dothideomycete-plant interactions illuminated by genome sequencing RT and EST analysis of the wheat pathogen Stagonospora nodorum."; RL Plant Cell 19:3347-3368(2007). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH445336; EAT84387.1; -; Genomic_DNA. DR RefSeq; XP_001798436.1; XM_001798384.1. DR EnsemblFungi; SNOT_08111; SNOT_08111; SNOG_08111. DR GeneID; 5975334; -. DR KEGG; pno:SNOG_08111; -. DR KO; K10997; -. DR OMA; MTVNHHR; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1177 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301745. SQ SEQUENCE 1177 AA; 134137 MW; 28B90431C5291508 CRC64; MAQTTLDDWA KDPVDPEIRA HVHSLITALG GIGDDGTYSL GDDALLCLKD LRKWLKFGDG QLNRRDVARC MAEANLVKGD LLEILAKISP KAIEDKWRHK IAVAALELLV PLTWPFEIDP IEATVNHHRH GPYIQLAQIG YKRAILQFDR DRTLQTAVKI ALPSMAVPLR ERTPRDEGII RIALYFIRNI AMLSPPTSAP MDIDEAEVSR SATIDTFHEQ DIFQVLLSVA SSIGEDFVAQ DVIVLEILFF LLKGIDAEKL FMEDKKLGTK NADELKNLMQ KEKAMLAGYA RNAPTRHNRF GTMIWVKRDD EKVTTISGQD VLGKAQASMQ KMDQTKKWNK PRRPGKKVDG EQEREEFDLP VALTVSARKH IKAFVEEFLD SSFNPLFLHL RKAIERETER VEIRHSRQFF YLASWFLRAE CARRRTMKER AADPKDPAVL TAEDESYGLV AEVMNQETFI LLNRFMQKSQ DEKAWQDLNA GMKCFTQILL TVHEMSESAL EDDQEIAENI QNRIFYEEST HDRVVMILRS YNGQGFGYLD AVTELSHVFL RMLERYAKQN VDLQVKSKRR ARKIKKKVAE THGANGDEEG QVSDTEDIQQ AQRTVSERKF DFQRFAAKFV NQSSVDTFVA FARYFSDLDT EQLKRIHRFF HRVAFKMELG VLLCRVDILQ LFTKMMKGPG GLDPESPAYK EWDEFVRHFF RQVVKKVQER PELVVEMLFS KIPATLFFLD HGYDREITKS TPRAPAELEV KPGMEVPEQI GVAVGVLINQ AKSDALHWVR DILISAAEER KAWEGAEEAR KALAAAERPA GEEVAENTEE ESPKPPSILV KPDSEERRLA MFKDNKLRLL MTLVGFSRLG EAHDPDATWI IPSAFTSTDL EFAIDLLRKY EFDPPTYEDG KGPEDLIRNK ASAARRSTRR VDFDDDDEEA ENAVEEDHGE YRAGKATERK PDGERKKLKR RQRVGTPVEL DDEEKDRRAE ARRKKELEKF AKQKSTEFVH DSDEEDDDDK DMEFFRREEA LRTEIMKAFG KSLTAGSTET ATSKKRKAED STSRTKRRKT PPKRKAQPFA DSDDSDEDVQ DAATPSSRAP SLSARDMIHD ESEVEDEATD TPLSSQHANG VHESDEDTTT GATASITVKS QDVVMADDDD EEDEATPVAR RPMARKRGAF IVDSDSE // ID TOF1_PICGU Reviewed; 1216 AA. AC A5DJ85; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 10-FEB-2009, sequence version 2. DT 14-MAY-2014, entry version 28. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=PGUG_03336; OS Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM OS 1539 / NBRC 10279 / NRRL Y-324) (Yeast) (Candida guilliermondii). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; Meyerozyma. OX NCBI_TaxID=294746; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL RC Y-324; RX PubMed=19465905; DOI=10.1038/nature08064; RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S., RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., RA Agrafioti I., Arnaud M.B., Bates S., Brown A.J.P., Brunke S., RA Costanzo M.C., Fitzpatrick D.A., de Groot P.W.J., Harris D., RA Hoyer L.L., Hube B., Klis F.M., Kodira C., Lennard N., Logue M.E., RA Martin R., Neiman A.M., Nikolaou E., Quail M.A., Quinn J., RA Santos M.C., Schmitzberger F.F., Sherlock G., Shah P., RA Silverstein K.A.T., Skrzypek M.S., Soll D., Staggs R., Stansfield I., RA Stumpf M.P.H., Sudbery P.E., Srikantha T., Zeng Q., Berman J., RA Berriman M., Heitman J., Gow N.A.R., Lorenz M.C., Birren B.W., RA Kellis M., Cuomo C.A.; RT "Evolution of pathogenicity and sexual reproduction in eight Candida RT genomes."; RL Nature 459:657-662(2009). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CH408158; EDK39238.2; -; Genomic_DNA. DR RefSeq; XP_001483955.1; XM_001483905.1. DR STRING; 4929.A5DJ85; -. DR GeneID; 5126086; -. DR KEGG; pgu:PGUG_03336; -. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1216 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301746. SQ SEQUENCE 1216 AA; 139181 MW; A5F0E25019A0306C CRC64; MSDFDSYAAD SELEDFVVDD EPPVDNSNNP QNPQDESNEA SETRDRIRDL TTALQPNETP TQKLLKAHIS VLVTALGGPD HVGSLKDSSS EYKLGHDALA CLKDIKRWIK SVDEIGHKYD VALACADCGL VENDLTVMLC QWDSQQKHSN TSKRTTEKIM LSALEILVLL TWPVEMSSEM SENQQLNFVA VRKSQLVYKK HILSYNNGQT FKAVLRLALP TISKDTSDRE PRDNAILGLV LFFIRNMLYI EPPSLSTSSK LRKTMMEIDN LPANMRYDDV SINTVLSCFK RNKVLLFLLT MCGSLGSDFD RETFAPCCLE CIFLIVRGVE ARDLVDNVRP VPETNDANGN NLPTLSSTSD MALQDLLKEE KRRKKVQSQN ISTRHGRFGT LLSLQGENSS YVVSGQEALS SANQTFAQLD KSKKWNDRKH FKYDSDAFVN TTPNFITSTT ISLLKEFINE FLVGGCFNSL MSSVGWIFSG ASDLSYINEY EKASYFLTTA WFFAYKRARI EILKNRILNE NEDTLDYGSV AAGLSEVNFV LIIGYVRESF ERHYWDSLHV AMICFREMLL ISNSVFESKH KDTNSEQDEE DRDMAEGIIR KLFSLEQFVN LITHIPQSAS KHSPEYLSVC VSVVYILLKS FENFSKEDIK LYVQSKRKQR RNAKNFKNVD SLELKDIIEG SDEEIDEETV KQVSRERKFD FNKTEMKFFQ SSIVTAHIDF LSRYEDLTHE QIKQCLVYFH RLFIVRKDYS GLFRLDFLHV LNSLRDFLPR KSNIRNHVEE FTFHFMKRFK NLFRRFPNPV ELLFPRMEDE SLRTYLSLGE VVEKPIKKAK EREIRYAKEL EFTRSNFSED EKYKILVSAI YFEDNEKFLS WLIEELSRIV EIAEKDSEAS TIKLQVQGEY EPLVLENATV RFLLENVGFV VPESSSDECT CTVGTSELTQ SLEYIKKWLS VQPVAFDEDK DASHYLRVRD DANDGEFNIG YDENEDEIAF ETAPTNRYRE DLEALDNLEE LEARISSSNG VKGVARKKRR PKGKISDTKH RSKPSSTHRK PRNLGVHSDD EEDKPLKSGE YVHDSDDESD NEDARAFFER EEKLRRMLTE SGGIVNPQQL EEFKRAWGKI VGGEAVDNVL STLGLQTGAS QSSLPLASQS QVDSQPQIDS QPQIDSELQS QSLSQVVEDG PSVESTQESS SEEFLSADEE LPARKKRRVI DDSDEE // ID TOF1_PICST Reviewed; 1256 AA. AC A3LR41; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 24-JUL-2007, sequence version 2. DT 14-MAY-2014, entry version 33. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=PICST_88189; OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / OS NRRL Y-11545) (Yeast) (Pichia stipitis). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Debaryomycetaceae; OC Scheffersomyces. OX NCBI_TaxID=322104; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545; RX PubMed=17334359; DOI=10.1038/nbt1290; RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A., RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S., RA Passoth V., Richardson P.M.; RT "Genome sequence of the lignocellulose-bioconverting and xylose- RT fermenting yeast Pichia stipitis."; RL Nat. Biotechnol. 25:319-326(2007). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CP000497; ABN65319.2; -; Genomic_DNA. DR RefSeq; XP_001383348.2; XM_001383311.1. DR STRING; 4924.PICST_88189; -. DR GeneID; 4838311; -. DR KEGG; pic:PICST_88189; -. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000094158; -. DR KO; K10997; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus. FT CHAIN 1 1256 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301747. SQ SEQUENCE 1256 AA; 143745 MW; 6D29487D04DFC3AE CRC64; MSVSDIETER TRYYDAYDAD DAELDGFIVS DEENDNLENE NRNERDPDSR NQDDVDEYGQ PQIDRIRTMT EALAPNESQA SKVLRAHISV LVSALGGPDH TSNISPPPYK LGHDALACLK DIKRWIKSVD DRQDSYQVAL ACAESGLVIN DLIVILCQWD SKNKKKEDFR NKRTMEKIML ACLELLVLLT WSVELRPESS DKQKLLYYDV KKAQIKYKRA ILTYNKGQTL KAVIRLVLPI ISKERVDREP KDNAIMRLVL FFFRNILYVE PPSPSISKKS SKTIVVTDNM PEGVSYDDIS LSATISAFSK NRVLMLFLTL SSGIGVDFDS RFLGPTLLEC IHLLVRGVDP NDILKLKQMR IPTEINDPGN SSSPFHNVPP ASSTTGLQLQ DLLAKESKIK NSQTQSMSTR HGRFGSLLSI RGDHSMSFVV SGQEALINAG QTMQKLDRSK KWKNRSYFKY DSDEYTKSSN TTYMNYGGLV ILHEFIESFL AGGCFNILIE KLSSVFSSSD SILEKEYETA TFFLTIAWFF QYKREKTVLY SSGTTNLQPI GEEDDRNDFG SVGAALSQVN FILLVKYCVD SFSISPKRWS SLHVVLICLK ELLEISNTLF TRSSSSAGDE EQNELDRELA EGIISHLLVT QDFLSILYHL PQTASRHSPE YLKVCISVVH ILLKTLKNFA EEDVKLFIQT TRRNSKKKAN KESNDQSDAV EQVDESDTED KRTHARVTRE RKINYERTEV KFFHQDTVST YIEYLSRYED LTHYEIKKCL TYFHRLFVVR KDFNGLYRLD FMQVLHKLRD YLPSQSNIRG QVDEFIYYFM KKFKASIERF PNPIEILFPR FEDAESKTYL ATGELYIQTE REIRSANVKR FEPGKPLEFV RHFEDNEKYK ILVSALYEQG LSNMLVCLVE DLQRIHGIKQ LDEDVDEVLQ LKEDFRQYVL TNSHLRLLLR TVGLIPGYSL SQECQVPSKL TSSDIDSAIT LIKKWMGLQP ATFEDGKDPS YFLRSTGDTV DRPIDYSDSE DDIAFEITPK DRPNESHYDM LTELDELERA ISGAENREKG KARKRGNKSS STIKKKSLQS RSRRPPRFNV DSDDESELRK EVKSSEFVHD SDDESDDEAF FEREERLRQM LNSSGGIVNA QQLSEFKKVW ASLESTGGIA TASQVVRAVE SVANISDGVD THSHQDDKSQ PSDSENEDSS EEVSEVQIRK RLRIEDDEND SDNNVSENYV SAEEGEEATP TVKRKKRLVI SDDEDE // ID TOF1_USTMA Reviewed; 1251 AA. AC Q4PAB2; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 19-JUL-2005, sequence version 1. DT 14-MAY-2014, entry version 34. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; ORFNames=UM02951; OS Ustilago maydis (strain 521 / FGSC 9021) (Corn smut fungus). OC Eukaryota; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; OC Ustilaginomycetes; Ustilaginales; Ustilaginaceae; Ustilago. OX NCBI_TaxID=237631; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=521 / FGSC 9021; RX PubMed=17080091; DOI=10.1038/nature05248; RA Kaemper J., Kahmann R., Boelker M., Ma L.-J., Brefort T., RA Saville B.J., Banuett F., Kronstad J.W., Gold S.E., Mueller O., RA Perlin M.H., Woesten H.A.B., de Vries R., Ruiz-Herrera J., RA Reynaga-Pena C.G., Snetselaar K., McCann M., Perez-Martin J., RA Feldbruegge M., Basse C.W., Steinberg G., Ibeas J.I., Holloman W., RA Guzman P., Farman M.L., Stajich J.E., Sentandreu R., RA Gonzalez-Prieto J.M., Kennell J.C., Molina L., Schirawski J., RA Mendoza-Mendoza A., Greilinger D., Muench K., Roessel N., Scherer M., RA Vranes M., Ladendorf O., Vincon V., Fuchs U., Sandrock B., Meng S., RA Ho E.C.H., Cahill M.J., Boyce K.J., Klose J., Klosterman S.J., RA Deelstra H.J., Ortiz-Castellanos L., Li W., Sanchez-Alonso P., RA Schreier P.H., Haeuser-Hahn I., Vaupel M., Koopmann E., Friedrich G., RA Voss H., Schlueter T., Margolis J., Platt D., Swimmer C., Gnirke A., RA Chen F., Vysotskaia V., Mannhaupt G., Gueldener U., RA Muensterkoetter M., Haase D., Oesterheld M., Mewes H.-W., RA Mauceli E.W., DeCaprio D., Wade C.M., Butler J., Young S.K., RA Jaffe D.B., Calvo S.E., Nusbaum C., Galagan J.E., Birren B.W.; RT "Insights from the genome of the biotrophic fungal plant pathogen RT Ustilago maydis."; RL Nature 444:97-101(2006). CC -!- FUNCTION: Involved in chromosome segregation during meiosis and CC DNA damage repair (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; AACP01000101; EAK84123.1; -; Genomic_DNA. DR RefSeq; XP_759098.1; XM_754005.1. DR STRING; 5270.UM02951.1; -. DR EnsemblFungi; UM02951T0; UM02951P0; UM02951. DR GeneID; 3631053; -. DR KEGG; uma:UM02951.1; -. DR eggNOG; NOG310534; -. DR KO; K10997; -. DR OMA; LEMASAM; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1251 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301748. SQ SEQUENCE 1251 AA; 141410 MW; 56B5EC32D8E2A1BD CRC64; MATKDDYSED LENDADLMTD FSDDEYGYRH EEGHNDEEAA PNIEEIREAA ADLCNQIGEY DYGDEHDWDG EQYPRLKRWK HRPRALGSLR SLRKLWKMDD DDPTRKVARA FAENEVLQHT ILPALLESAG QGKEGDAIAL ACTDLLTAMT WPFDGLEELR EQEKQGHLDL AELSEITLLD EHLVNYKSVI LRNRSLDQQH DVLGVVMRYL LLPNLATKHH ERSTLATGII SMCLHLFRNL LAIRDPVTTS LSSVERLSNA NLQSELILSM HKHHILDALL MLSSSAETQA YNAWNAVASE CIFHIFVGTM VKTIAEPTFS GSGTRMSHDS TPNASASNTA GSSSNANAGP ISSLAESLAM ETKLKRASAS GKIATRHSRF GTTINFVGPD GELRVARNQA ALIKPVAQLA DEANQKGRRR AQRRKDAQEK GAPKLKSKWT PDAALVLQEW ADTFVQSGFE PLAKSVLKDI RSERDKLGDL DVARVRIMQL GAFFLEYFLL RRTTAAKRRN AAKTAGSVQS TFAQRALDLQ EPDEQHERSG QSAEQPEEAE EWPFELVSQW LEPWAFRMVL VRTIQSQETK AWLEFVASVR LWIVLLRLVD ELANSKKESE RDVAEGLQAE FYYMGETLEA CHAIFRSYTT QSFAFLDAII AFAYVMPKML ERYASNRDHM YVQAKKQVHR SRQDGDLDTD QDEARQIKEQ LQETRSEREF RFADFQRKLA TKQLAKACIV YLRRWKDNNG TEDQLNELVT VMHRIAIKAN DYRQFFLATH RDYLRFMISG DTISAFEARA PTSAPNLRKL IDYILRKFSK LSPEEQSIYN AGKQPTRQPK PPRMPAEIVV RPGMTPDQEI GVAVGLLLKK EKMPAVLWIK SALEMASAMR TELVLRYEEE EAQRSIQGAG DDMMLLGELE KHNESPVERF QPYELAYHGN DELRTDASLM PELKLLCRLV GLEANDNELV NWRWSVPKEI LPVHLDQKIE TIERYIREPL DTHGRELTAL VMRIRKPRVA GEADADVLDP ADLPDGWNGA QSDSDEDGDY FDRIRASRSL VSADHVAAEG GLLRRSGPKK KLSHPTKGDG SRKKKQIQRI KQDIIDDSDD EFAFALADLQ PQARTDADAD SSSDDKEEED DDDDNMDDQE TPATSSVADL QEQFDQGKSN ALDALRTAKQ QRSNTEQPPL QDAGERINRR MDTKRLFLAD SDEDDDDVLA LSSQEPADIS ATSDRTATGP SVWAGIAKKR RLAILDDEDE D // ID TOF1_YARLI Reviewed; 1054 AA. AC Q6CFJ2; DT 11-SEP-2007, integrated into UniProtKB/Swiss-Prot. DT 16-AUG-2004, sequence version 1. DT 14-MAY-2014, entry version 43. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=YALI0B06512g; OS Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida OS lipolytica). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Dipodascaceae; Yarrowia. OX NCBI_TaxID=284591; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=CLIB 122 / E 150; RX PubMed=15229592; DOI=10.1038/nature02579; RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., RA Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., RA Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., RA Barnay S., Blanchin S., Beckerich J.-M., Beyne E., Bleykasten C., RA Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., RA Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., RA Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., RA Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., RA Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., RA Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., RA Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., RA Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., RA Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., RA Wincker P., Souciet J.-L.; RT "Genome evolution in yeasts."; RL Nature 430:35-44(2004). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors (By similarity). CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3 (By similarity). CC -!- SUBCELLULAR LOCATION: Nucleus (By similarity). CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; CR382128; CAG82801.1; -; Genomic_DNA. DR RefSeq; XP_500570.1; XM_500570.1. DR STRING; 4952.Q6CFJ2; -. DR EnsemblFungi; CAG82801; CAG82801; YALI0_B06512g. DR GeneID; 2907602; -. DR KEGG; yli:YALI0B06512g; -. DR eggNOG; NOG328380; -. DR KO; K10997; -. DR OMA; GEDCLEA; -. DR OrthoDB; EOG7PGF01; -. DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell. DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0008156; P:negative regulation of DNA replication; IEA:UniProtKB-KW. DR InterPro; IPR006906; Timeless. DR InterPro; IPR007725; TIMELESS_C. DR Pfam; PF04821; TIMELESS; 1. DR Pfam; PF05029; TIMELESS_C; 1. PE 3: Inferred from homology; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Reference proteome. FT CHAIN 1 1054 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000301749. SQ SEQUENCE 1054 AA; 120710 MW; 1A239A67C38E6A19 CRC64; MEEVDRLVTA SITSIVSALG GCDLASEDAS YVLGEEALAC LKDVKQWLRA FDEKLGRSDV AKCIASTTLV VSDIPSILST WNTQSEAGQA SKKMDRVALA CLEILVPLLW PIEINDETPD NVVASADLLR QAQIRYKRAL LGHPSKSILK AVVRLCIPSV AKSKADRDQR DIGIMKLVVF FIRNMLAIDP MEANGKTDDI NRSAILEAFE NQGVLDLMLT LGSCTGYDIV GVDLPLLDSL YQMVKGLDVV EIFETSPNEP DNQLKNLLDT ERRNKPVGSS RHSRFASTMT VLHNGSKISV TGPTASIEKS LEKFDKSKQP GRRLTKPTTG VWEVPVFVGH SAKRYIRVFS ELFNDSAFNP LMQTVRKALE QEDDIGPAFK HYLVVLKWFL GVEMHRKTPD FGLIASVVNQ EAFIIIMRSI RQGVQAKNWT MVKTAMDSFK TTLVVVNLMS DEEVASNIKA RLFYEEEYLT MLADLTRRWA LPLTFLQSAV DMTHTLIKTL ESFTKANTTL YVRRRRLRAQ KKADDTGNVE DLESLPGEEH ESAIESRERK FNFSSFESRY FHEDTFTTYR MVLSSFQQLD NCYLGWCLKF LDRAFNKRKC RVMLFRLDYL QLFRTMVKEL NSSNPWRKPF EHFFKKYMRQ MIPMMKERPC LMVEVIFAKI PGTLHYLESG EEKPVRELKE RTSKFVYEFT EGDDIPEERK VCILVASLLD EEKKQLVEWF IDELDSLLRA RTGDTQVLNP PKATDELNVP KSIDEDDKFR LLMELVGFTL SRIPKSSVGC KTLCSLPGEV SRADIERATG WLKQWYSTPV DFEPFNKIKR VRRDDKERRG AGGDKEGSQD AEEDDELPLF LASDSEDDIE NINDEMFAPV PKEKQQKTKQ KLKRKGTSKS TREREKQRDY TAKTTIDIPM SYKSADFIGA SDDDSDDERD RKFFEKENEL REELRKAEPT INLEEKVDKA FKRQYAYVSD GEEEPLSETE SHKQYREKVD EDRDDLSHMA ERENRQYDFG DEGHDSDNLE IIDDDSKSPV AAEGTTSSQP IRKRRIVDDS DDDE // ID TOF1_YEAST Reviewed; 1238 AA. AC P53840; D6W0S1; DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot. DT 01-OCT-1996, sequence version 1. DT 11-JUN-2014, entry version 114. DE RecName: Full=Topoisomerase 1-associated factor 1; GN Name=TOF1; OrderedLocusNames=YNL273W; ORFNames=N0636; OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; OC Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces. OX NCBI_TaxID=559292; RN [1] RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=ATCC 204508 / S288c; RX PubMed=9169873; RA Philippsen P., Kleine K., Poehlmann R., Duesterhoeft A., Hamberg K., RA Hegemann J.H., Obermaier B., Urrestarazu L.A., Aert R., Albermann K., RA Altmann R., Andre B., Baladron V., Ballesta J.P.G., Becam A.-M., RA Beinhauer J.D., Boskovic J., Buitrago M.J., Bussereau F., Coster F., RA Crouzet M., D'Angelo M., Dal Pero F., De Antoni A., del Rey F., RA Doignon F., Domdey H., Dubois E., Fiedler T.A., Fleig U., Floeth M., RA Fritz C., Gaillardin C., Garcia-Cantalejo J.M., Glansdorff N., RA Goffeau A., Gueldener U., Herbert C.J., Heumann K., Heuss-Neitzel D., RA Hilbert H., Hinni K., Iraqui Houssaini I., Jacquet M., Jimenez A., RA Jonniaux J.-L., Karpfinger-Hartl L., Lanfranchi G., Lepingle A., RA Levesque H., Lyck R., Maftahi M., Mallet L., Maurer C.T.C., RA Messenguy F., Mewes H.-W., Moestl D., Nasr F., Nicaud J.-M., RA Niedenthal R.K., Pandolfo D., Pierard A., Piravandi E., Planta R.J., RA Pohl T.M., Purnelle B., Rebischung C., Remacha M.A., Revuelta J.L., RA Rinke M., Saiz J.E., Sartorello F., Scherens B., Sen-Gupta M., RA Soler-Mira A., Urbanus J.H.M., Valle G., Van Dyck L., Verhasselt P., RA Vierendeels F., Vissers S., Voet M., Volckaert G., Wach A., RA Wambutt R., Wedler H., Zollner A., Hani J.; RT "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV RT and its evolutionary implications."; RL Nature 387:93-98(1997). RN [2] RP GENOME REANNOTATION. RC STRAIN=ATCC 204508 / S288c; RX PubMed=24374639; DOI=10.1534/g3.113.008995; RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R., RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S., RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., RA Cherry J.M.; RT "The reference genome sequence of Saccharomyces cerevisiae: Then and RT now."; RL G3 (Bethesda) 4:389-398(2014). RN [3] RP IDENTIFICATION. RX PubMed=10028183; RX DOI=10.1002/(SICI)1097-0061(19990115)15:1<35::AID-YEA340>3.3.CO;2-I; RA Park H., Sternglanz R.; RT "Identification and characterization of the genes for two RT topoisomerase I-interacting proteins from Saccharomyces cerevisiae."; RL Yeast 15:35-41(1999). RN [4] RP FUNCTION. RX PubMed=11156979; RA Foss E.J.; RT "Tof1p regulates DNA damage responses during S phase in Saccharomyces RT cerevisiae."; RL Genetics 157:567-577(2001). RN [5] RP FUNCTION, AND SUBCELLULAR LOCATION. RX PubMed=12944972; DOI=10.1038/nature01900; RA Katou Y., Kanoh Y., Bando M., Noguchi H., Tanaka H., Ashikari T., RA Sugimoto K., Shirahige K.; RT "S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication- RT pausing complex."; RL Nature 424:1078-1083(2003). RN [6] RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. RX PubMed=14562095; DOI=10.1038/nature02026; RA Huh W.-K., Falvo J.V., Gerke L.C., Carroll A.S., Howson R.W., RA Weissman J.S., O'Shea E.K.; RT "Global analysis of protein localization in budding yeast."; RL Nature 425:686-691(2003). RN [7] RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS]. RX PubMed=14562106; DOI=10.1038/nature02046; RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., RA Dephoure N., O'Shea E.K., Weissman J.S.; RT "Global analysis of protein expression in yeast."; RL Nature 425:737-741(2003). RN [8] RP FUNCTION, AND INTERACTION WITH CSM3. RX PubMed=14742714; DOI=10.1091/mbc.E03-08-0619; RA Mayer M.L., Pot I., Chang M., Xu H., Aneliunas V., Kwok T., Newitt R., RA Aebersold R., Boone C., Brown G.W., Hieter P.; RT "Identification of protein complexes required for efficient sister RT chromatid cohesion."; RL Mol. Biol. Cell 15:1736-1745(2004). RN [9] RP FUNCTION, AND INTERACTION WITH WSS1. RX PubMed=15598824; DOI=10.1093/nar/gkh994; RA O'Neill B.M., Hanway D., Winzeler E.A., Romesberg F.E.; RT "Coordinated functions of WSS1, PSY2 and TOF1 in the DNA damage RT response."; RL Nucleic Acids Res. 32:6519-6530(2004). RN [10] RP FUNCTION, IDENTIFICATION IN THE FPC COMPLEX, AND IDENTIFICATION BY RP MASS SPECTROMETRY. RX PubMed=15755447; DOI=10.1016/j.jmb.2005.01.041; RA Nedelcheva M.N., Roguev A., Dolapchiev L.B., Shevchenko A., RA Taskov H.B., Shevchenko A., Stewart A.F., Stoynov S.S.; RT "Uncoupling of unwinding from DNA synthesis implies regulation of MCM RT helicase by Tof1/Mrc1/Csm3 checkpoint complex."; RL J. Mol. Biol. 347:509-521(2005). RN [11] RP FUNCTION. RX PubMed=16137625; DOI=10.1016/j.molcel.2005.07.028; RA Tourriere H., Versini G., Cordon-Preciado V., Alabert C., Pasero P.; RT "Mrc1 and Tof1 promote replication fork progression and recovery RT independently of Rad53."; RL Mol. Cell 19:699-706(2005). RN [12] RP FUNCTION. RX PubMed=16024805; DOI=10.1128/MCB.25.15.6707-6721.2005; RA Archambault V., Ikui A.E., Drapkin B.J., Cross F.R.; RT "Disruption of mechanisms that prevent rereplication triggers a DNA RT damage response."; RL Mol. Cell. Biol. 25:6707-6721(2005). RN [13] RP INTERACTION WITH ESC4. RX PubMed=16569515; DOI=10.1016/j.dnarep.2006.02.005; RA Chin J.K., Bashkirov V.I., Heyer W.-D., Romesberg F.E.; RT "Esc4/Rtt107 and the control of recombination during replication."; RL DNA Repair 5:618-628(2006). RN [14] RP FUNCTION OF THE FPC COMPLEX. RX PubMed=16219777; DOI=10.1534/genetics.105.046128; RA Redon C., Pilch D.R., Bonner W.M.; RT "Genetic analysis of Saccharomyces cerevisiae H2A serine 129 mutant RT suggests a functional relationship between H2A and the sister- RT chromatid cohesion partners Csm3-Tof1 for the repair of topoisomerase RT I-induced DNA damage."; RL Genetics 172:67-76(2006). RN [15] RP FUNCTION OF THE FPC COMPLEX. RX PubMed=16418273; DOI=10.1073/pnas.0506540103; RA Mohanty B.K., Bairwa N.K., Bastia D.; RT "The Tof1p-Csm3p protein complex counteracts the Rrm3p helicase to RT control replication termination of Saccharomyces cerevisiae."; RL Proc. Natl. Acad. Sci. U.S.A. 103:897-902(2006). RN [16] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1213, AND IDENTIFICATION RP BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]. RC STRAIN=ADR376; RX PubMed=17330950; DOI=10.1021/pr060559j; RA Li X., Gerber S.A., Rudner A.D., Beausoleil S.A., Haas W., Villen J., RA Elias J.E., Gygi S.P.; RT "Large-scale phosphorylation analysis of alpha-factor-arrested RT Saccharomyces cerevisiae."; RL J. Proteome Res. 6:1190-1197(2007). RN [17] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-626; SER-654 AND RP SER-1213, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE RP ANALYSIS]. RX PubMed=18407956; DOI=10.1074/mcp.M700468-MCP200; RA Albuquerque C.P., Smolka M.B., Payne S.H., Bafna V., Eng J., Zhou H.; RT "A multidimensional chromatography technology for in-depth RT phosphoproteome analysis."; RL Mol. Cell. Proteomics 7:1389-1396(2008). RN [18] RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1056; SER-1058 AND RP SER-1213, AND IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE RP ANALYSIS]. RX PubMed=19779198; DOI=10.1126/science.1172867; RA Holt L.J., Tuch B.B., Villen J., Johnson A.D., Gygi S.P., Morgan D.O.; RT "Global analysis of Cdk1 substrate phosphorylation sites provides RT insights into evolution."; RL Science 325:1682-1686(2009). CC -!- FUNCTION: Forms a fork protection complex (FPC) with CSM3 and CC which is required for chromosome segregation during meiosis and CC DNA damage repair. FPC coordinates leading and lagging strand CC synthesis and moves with the replication fork. FPC stabilizes CC replication forks in a configuration that is recognized by CC replication checkpoint sensors and protects stalled replication CC forks against the fork-releasing activity of RRM3 helicase. CC -!- SUBUNIT: Component of the fork protection complex (FPC) consisting CC of TOF1 and CSM3. Interacts with WSS1 and ESC4. CC -!- INTERACTION: CC Q08032:CDC45; NbExp=3; IntAct=EBI-28257, EBI-4292; CC Q04659:CSM3; NbExp=8; IntAct=EBI-28257, EBI-28093; CC -!- SUBCELLULAR LOCATION: Nucleus. Note=Associated with chromatin CC during S phase. CC -!- MISCELLANEOUS: Present with 952 molecules/cell in log phase SD CC medium. CC -!- SIMILARITY: Belongs to the timeless family. CC ----------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution-NoDerivs License CC ----------------------------------------------------------------------- DR EMBL; Z71549; CAA96181.1; -; Genomic_DNA. DR EMBL; BK006947; DAA10287.1; -; Genomic_DNA. DR PIR; S63247; S63247. DR RefSeq; NP_014126.1; NM_001183111.1. DR ProteinModelPortal; P53840; -. DR BioGrid; 35567; 206. DR DIP; DIP-4272N; -. DR IntAct; P53840; 8. DR MINT; MINT-529011; -. DR STRING; 4932.YNL273W; -. DR MaxQB; P53840; -. DR PaxDb; P53840; -. DR EnsemblFungi; YNL273W; YNL273W; YNL273W. DR GeneID; 855448; -. DR KEGG; sce:YNL273W; -. DR CYGD; YNL273w; -. DR SGD; S000005217; TOF1. DR eggNOG; NOG310534; -. DR HOGENOM; HOG000057108; -. DR KO; K10997; -. DR OMA; GDDCLAC; -. DR OrthoDB; EOG7PGF01; -. DR BioCyc; YEAST:G3O-33267-MONOMER; -. DR NextBio; 979352; -. DR Genevestigator; P53840; -. DR GO; GO:0005829; C:cytosol; IDA:SGD. DR GO; GO:0000228; C:nuclear chromosome; IPI:SGD. DR GO; GO:0043596; C:nuclear replication fork; IDA:SGD. DR GO; GO:0005634; C:nucleus; IDA:SGD. DR GO; GO:0031298; C:replication fork protection complex; IDA:SGD. DR GO; GO:0005515; F:protein binding; IPI:IntAct. DR GO; GO:0006281; P:DNA repair; IMP:SGD. DR GO; GO:0006260; P:DNA replication; IMP:SGD. DR GO; GO:0000076; P:DNA replication checkpoint; IMP:SGD. DR GO; GO:0043570; P:maintenance of DNA repeat elements; IMP:SGD. DR GO; GO:0007126; P:meiotic nuclear division; IEA:UniProtKB-KW. DR GO; GO:0007064; P:mitotic sister chromatid cohesion; IMP:SGD. DR GO; GO:0043111; P:replication fork arrest; IMP:SGD. DR GO; GO:0048478; P:replication fork protection; IMP:SGD. DR InterPro; IPR006906; Timeless. DR Pfam; PF04821; TIMELESS; 1. PE 1: Evidence at protein level; KW Cell cycle; Complete proteome; DNA damage; DNA repair; KW DNA replication inhibitor; Meiosis; Nucleus; Phosphoprotein; KW Reference proteome. FT CHAIN 1 1238 Topoisomerase 1-associated factor 1. FT /FTId=PRO_0000072620. FT MOD_RES 626 626 Phosphoserine. FT MOD_RES 654 654 Phosphoserine. FT MOD_RES 1056 1056 Phosphoserine. FT MOD_RES 1058 1058 Phosphoserine. FT MOD_RES 1213 1213 Phosphoserine. SQ SEQUENCE 1238 AA; 141120 MW; CF8FEC33EE0088E9 CRC64; MSADLQQGTT NAADFSLTVL RARIALLATA IGGPDYTSQI DPPPYKLGDD CLACLKDLKR WFKLVDDQQK RWDVAMAVAE YRILTDDLLP ILIDWENKCS LAAKLAKNNP DHEEFRNKAY YDKIALNCLQ LLVLMTWPLI VTEQSSSNQI TLYGELKKHQ LVYKKTILSM ESGKVLRAAI RLALDVIKID RLSRTPRDNM VLKLVLNFFR NVIAIEPGEF TINTKKSMPK KGITSIDTLP PNVSMDDISL NTVISSFHKN KVFGFLLTLT SSLSKEFDQD FINIPLLEIM FYFTKDVNQE LLFPRQFETG THSKVVNKNE SSSANNIVTS AGFELSKLLQ KEHQMRKNVI KHTSARHSRF GGLLSIQTPD KTRLTVSGSQ ALVDEKIALQ KLDDSKKWNK RIIKKHQSVA AEGLPNSLLN SQTGKAIFFT ESNGKHFKEF INNFIDSGFN ILLHSVTNYF TTEQDRMVTL EQVEYLLFFA WFVKYQLLRS KIDNSADIKQ VSEALKEVTF ILVSSLLRSA YDLKNWTVTH AGMIAFNELL NLVSRTKAAQ EEDSTDIEFI VSRLFSDERI QLLSNLPKIG SKYSLQFMKS CIELTHSVLK VLEQYSDDKT LVIEGKSRRQ KKFNISEGDI TKLIEEENVD RDEALDILTS SLRSIEVNFQ KVQANYMTEP VIETYINFLE RFRELEDDSI KKVFSFFHRV FVQAKEQALL FRFDLIILLR EMLSPDGLDR MSRSRKYVSQ FSDYFLARLK KRLKKSPAWF VGLLFPPLHN SEVGFYQRYG EYNVLNNESM YAAPASQFKP IPDEEALPPS ILLDMKYGVL VSTLLDDGKT ELLDQLLKHI THTLDIFKSW LTVNVNAGKE TVNPPNEYFT LTGVLNNDPI FKDKDYRALL LLIGYSIPRK INEPCFLPGT VEVSDLTVSC ELVKKYLSTP FETPNGLPSS SYLLRVRSEK DSFSHNEQDG WEGDDDYDYN DPYIVPDDQI LSKSDAAYFK DLDNNASDKL KGTKFSKGIA RSKKKDKRKR RKGEAKTNLP MFGDQDDERP QTVRERHGVF SKEFISDSED DEDLMNPIFF ENETYMRWLL DKNNGQLTED RYIQFAKFAA ERMNNGGVVT GDYTSLFGGS IPSIESIRAT ESSSFAPDKS LISLASHVAS EMSIFDVNNN NNNQLSDDDV NSESRNSLGS SQPSNSQNMF QSEVYSRKES TKRSLEASAA DESDEDEEAI RLFGKKSRVV LSQGDSDD //