REMARK 3 HETEROGEN ATOMS : 8 REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM HET TRS A 701 8 HETNAM TRS 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL HETSYN TRS TRIS BUFFER HETATM 2444 C TRS A 701 45.426 -1.678 -4.085 1.00 82.63 C HETATM 2445 C1 TRS A 701 46.111 -1.676 -5.455 1.00 84.22 C HETATM 2446 C2 TRS A 701 44.760 -0.324 -3.762 1.00 85.84 C HETATM 2447 C3 TRS A 701 46.397 -2.108 -2.990 1.00 84.14 C HETATM 2448 N TRS A 701 44.337 -2.721 -4.112 1.00 65.07 N HETATM 2449 O1 TRS A 701 45.204 -1.330 -6.496 1.00 89.23 O HETATM 2450 O2 TRS A 701 45.606 0.680 -3.211 1.00 61.41 O HETATM 2451 O3 TRS A 701 47.755 -1.968 -3.352 1.00 62.81 O HETATM 2452 O AHOH A 801 37.623 10.741 11.892 0.39 23.46 O HETATM 2453 O HOH A 802 40.372 17.443 12.230 1.00 49.20 O HETATM 2454 O HOH A 803 21.653 26.272 -0.664 1.00 84.33 O HETATM 2455 O HOH A 804 65.158 15.926 -11.653 1.00 69.29 O HETATM 2456 O HOH A 805 46.286 31.701 -9.729 1.00 60.19 O HETATM 2457 O HOH A 806 36.865 1.816 -6.044 1.00 56.50 O HETATM 2458 O HOH A 807 27.915 18.510 -15.657 1.00 64.33 O HETATM 2459 O HOH A 808 46.624 21.814 23.510 1.00 48.41 O HETATM 2460 O HOH A 809 52.365 27.622 -11.184 1.00 66.70 O HETATM 2461 O HOH A 810 31.928 10.563 -15.293 1.00 61.02 O HETATM 2462 O HOH A 811 54.376 1.451 15.168 1.00 56.82 O HETATM 2463 O HOH A 812 31.006 4.597 -2.043 1.00 53.07 O HETATM 2464 O HOH A 813 34.788 3.015 2.960 1.00 31.09 O HETATM 2465 O HOH A 814 43.680 -0.732 10.025 1.00 49.62 O HETATM 2466 O HOH A 815 35.333 11.025 14.370 1.00 63.67 O HETATM 2467 O HOH A 816 23.140 22.164 -5.207 1.00 98.76 O HETATM 2468 O HOH A 817 63.640 12.646 8.653 1.00 37.83 O HETATM 2469 O HOH A 818 37.107 21.359 12.789 1.00 57.53 O HETATM 2470 O HOH A 819 63.372 2.562 11.130 1.00 69.83 O HETATM 2471 O HOH A 820 58.895 33.430 6.383 1.00 73.02 O HETATM 2472 O HOH A 821 37.072 5.037 10.721 1.00112.07 O HETATM 2473 O HOH A 822 54.318 3.899 4.359 1.00 26.50 O HETATM 2474 O HOH A 823 57.817 21.086 -9.848 1.00 73.65 O HETATM 2475 O HOH A 824 51.367 17.964 -7.312 1.00 25.44 O HETATM 2476 O HOH A 825 22.886 6.775 12.591 1.00 74.45 O HETATM 2477 O HOH A 826 62.795 21.411 -12.044 1.00 75.97 O HETATM 2478 O HOH A 827 50.432 34.266 -5.181 1.00 75.67 O HETATM 2479 O HOH A 828 52.169 33.254 6.552 1.00 42.70 O HETATM 2480 O HOH A 829 25.396 12.046 -15.102 1.00 61.14 O HETATM 2481 O HOH A 830 46.597 28.813 16.327 1.00 48.30 O HETATM 2482 O HOH A 831 48.655 -6.230 5.238 1.00 42.93 O HETATM 2483 O HOH A 832 40.622 28.596 -10.648 1.00 80.79 O HETATM 2484 O HOH A 833 44.220 4.349 6.677 1.00 25.04 O HETATM 2485 O HOH A 834 47.011 4.129 3.481 1.00 28.90 O HETATM 2486 O HOH A 835 45.261 21.860 -15.429 1.00 44.88 O HETATM 2487 O HOH A 836 34.797 20.164 13.714 1.00 56.72 O HETATM 2488 O HOH A 837 66.168 12.105 -8.926 1.00 69.33 O HETATM 2489 O HOH A 838 45.708 3.057 14.011 1.00 65.55 O HETATM 2490 O HOH A 839 40.822 31.920 -6.221 1.00 69.85 O HETATM 2491 O HOH A 840 58.600 -1.556 5.823 1.00 65.02 O HETATM 2492 O HOH A 841 52.442 30.974 7.777 1.00 60.19 O HETATM 2493 O HOH A 842 66.427 8.062 5.974 1.00 74.54 O HETATM 2494 O HOH A 843 64.815 9.289 -3.550 1.00 64.72 O HETATM 2495 O HOH A 844 55.691 12.134 8.904 1.00 26.24 O HETATM 2496 O HOH A 845 45.792 21.950 -10.988 1.00 29.80 O HETATM 2497 O AHOH A 846 55.534 18.107 16.066 0.61 34.20 O HETATM 2498 O BHOH A 846 54.041 18.404 17.587 0.39 41.11 O HETATM 2499 O HOH A 847 55.892 9.252 9.048 1.00 26.72 O HETATM 2500 O AHOH A 848 65.092 29.705 7.278 0.59 32.44 O HETATM 2501 O BHOH A 848 65.796 27.854 7.784 0.41 33.50 O HETATM 2502 O HOH A 849 21.727 14.234 14.312 1.00 76.52 O HETATM 2503 O HOH A 850 44.714 27.001 9.215 1.00 33.84 O HETATM 2504 O HOH A 851 54.869 33.122 6.375 1.00 57.50 O HETATM 2505 O HOH A 852 38.469 5.470 -6.751 1.00 39.89 O HETATM 2506 O HOH A 853 39.161 23.375 14.108 1.00 44.98 O HETATM 2507 O HOH A 854 65.965 15.329 8.554 1.00 52.76 O HETATM 2508 O HOH A 855 48.125 26.299 -14.337 1.00 52.92 O HETATM 2509 O HOH A 856 50.370 0.391 7.500 1.00 32.30 O HETATM 2510 O HOH A 857 47.676 29.874 -7.795 1.00 49.17 O HETATM 2511 O HOH A 858 70.173 27.385 -1.156 1.00 62.01 O HETATM 2512 O HOH A 859 36.454 29.299 4.497 1.00 46.64 O HETATM 2513 O HOH A 860 62.543 36.437 -2.406 1.00 29.86 O HETATM 2514 O HOH A 861 67.432 24.208 -2.526 1.00 33.01 O HETATM 2515 O HOH A 862 69.406 22.522 7.818 1.00 60.87 O HETATM 2516 O HOH A 863 59.435 -3.476 14.647 1.00 68.51 O HETATM 2517 O HOH A 864 43.643 16.244 -12.266 1.00 43.72 O HETATM 2518 O HOH A 865 35.432 -1.496 1.565 1.00 51.41 O HETATM 2519 O HOH A 866 48.603 15.755 -9.742 1.00 36.99 O HETATM 2520 O HOH A 867 58.559 10.865 16.858 1.00 65.67 O HETATM 2521 O HOH A 868 51.315 0.529 -0.883 1.00 49.53 O HETATM 2522 O HOH A 869 69.905 30.353 0.903 1.00 34.34 O HETATM 2523 O HOH A 870 54.253 13.466 6.986 1.00 24.97 O HETATM 2524 O HOH A 871 31.940 25.052 14.159 1.00 55.64 O HETATM 2525 O HOH A 872 35.231 32.460 4.161 1.00 63.71 O HETATM 2526 O HOH A 873 56.088 17.190 -11.505 1.00 54.36 O HETATM 2527 O HOH A 874 35.259 21.574 -10.982 1.00 38.66 O HETATM 2528 O HOH A 875 39.330 1.382 9.976 1.00 68.71 O HETATM 2529 O HOH A 876 37.899 3.781 6.431 1.00 27.82 O HETATM 2530 O HOH A 877 49.544 5.063 14.027 1.00 39.98 O HETATM 2531 O HOH A 878 58.620 26.309 -11.987 1.00 86.17 O HETATM 2532 O HOH A 879 57.945 7.780 -1.942 1.00 33.45 O HETATM 2533 O HOH A 880 47.158 15.922 -7.390 1.00 28.10 O HETATM 2534 O HOH A 881 48.358 33.906 5.507 1.00 33.97 O HETATM 2535 O HOH A 882 38.705 28.634 17.225 1.00 68.43 O HETATM 2536 O HOH A 883 58.764 16.634 -6.496 1.00 31.02 O HETATM 2537 O HOH A 884 43.148 22.912 16.639 1.00 46.68 O HETATM 2538 O HOH A 885 38.943 30.648 7.759 1.00 69.87 O HETATM 2539 O HOH A 886 58.418 30.964 5.452 1.00 51.38 O HETATM 2540 O HOH A 887 65.941 29.478 2.333 1.00 28.50 O HETATM 2541 O HOH A 888 43.240 3.194 14.441 1.00 79.56 O HETATM 2542 O HOH A 889 52.265 -2.329 2.527 1.00 44.74 O HETATM 2543 O HOH A 890 68.221 12.230 -2.209 1.00 76.19 O HETATM 2544 O HOH A 891 58.530 -0.337 7.920 1.00 47.77 O HETATM 2545 O HOH A 892 30.261 31.959 1.625 1.00 85.78 O HETATM 2546 O HOH A 893 48.279 19.851 25.072 1.00 60.84 O HETATM 2547 O HOH A 894 51.835 -5.211 12.860 1.00 53.76 O HETATM 2548 O HOH A 895 27.425 11.203 -16.885 1.00 76.88 O HETATM 2549 O HOH A 896 28.242 10.165 -6.538 1.00 50.11 O HETATM 2550 O HOH A 897 59.899 -0.341 -0.368 1.00 81.58 O HETATM 2551 O HOH A 898 54.038 9.577 -8.391 1.00 57.01 O HETATM 2552 O HOH A 899 45.490 -2.685 3.712 1.00 28.33 O HETATM 2553 O HOH A 900 49.530 9.368 13.107 1.00 32.38 O HETATM 2554 O AHOH A 901 30.864 18.057 15.433 0.80 55.96 O HETATM 2555 O HOH A 902 70.647 28.003 6.958 1.00 61.77 O HETATM 2556 O HOH A 903 64.077 23.646 -10.512 1.00 71.69 O HETATM 2557 O HOH A 904 51.832 -1.813 0.008 1.00 80.45 O HETATM 2558 O HOH A 905 50.646 16.136 17.859 1.00 53.70 O HETATM 2559 O HOH A 906 43.308 15.447 10.847 1.00 28.22 O HETATM 2560 O HOH A 907 45.802 -3.793 11.198 1.00 38.71 O HETATM 2561 O HOH A 908 65.986 8.973 8.543 1.00 54.95 O HETATM 2562 O HOH A 909 72.823 27.366 -0.795 1.00 55.51 O HETATM 2563 O HOH A 910 55.675 9.950 17.785 1.00 60.42 O HETATM 2564 O HOH A 911 55.219 29.159 -10.240 1.00 71.87 O HETATM 2565 O AHOH A 912 55.362 33.058 -3.715 0.54 33.88 O HETATM 2566 O BHOH A 912 54.135 32.872 -5.519 0.46 39.43 O HETATM 2567 O HOH A 913 23.468 16.682 14.728 1.00 74.76 O HETATM 2568 O HOH A 914 30.100 26.475 8.412 1.00 64.44 O HETATM 2569 O HOH A 915 58.286 8.494 8.251 1.00 29.96 O HETATM 2570 O HOH A 916 51.796 28.610 14.583 1.00 40.27 O HETATM 2571 O HOH A 917 37.270 5.238 8.348 1.00 30.73 O HETATM 2572 O HOH A 918 61.611 38.831 1.331 1.00 51.14 O HETATM 2573 O HOH A 919 36.475 -3.446 5.127 1.00 61.34 O HETATM 2574 O HOH A 920 30.900 14.892 15.463 1.00 54.73 O HETATM 2575 O HOH A 921 51.077 18.327 20.616 1.00 73.56 O HETATM 2576 O HOH A 922 67.358 19.906 -12.348 1.00 60.95 O HETATM 2577 O HOH A 923 60.659 22.352 -11.339 1.00 49.16 O HETATM 2578 O HOH A 924 42.077 18.307 10.943 1.00 44.18 O HETATM 2579 O HOH A 925 39.977 20.837 12.885 1.00 50.34 O HETATM 2580 O HOH A 926 46.017 19.910 -16.934 1.00 54.49 O HETATM 2581 O HOH A 927 54.900 -3.667 2.245 1.00 74.26 O HETATM 2582 O HOH A 928 59.442 36.500 -0.038 1.00 52.59 O HETATM 2583 O HOH A 929 51.980 22.980 -14.512 1.00 73.08 O HETATM 2584 O HOH A 930 46.154 3.642 -3.383 1.00 44.86 O HETATM 2585 O HOH A 931 45.567 14.353 -9.858 1.00 42.07 O HETATM 2586 O HOH A 932 54.142 3.962 -2.843 1.00 41.33 O HETATM 2587 O HOH A 933 39.657 8.022 13.397 1.00 59.15 O HETATM 2588 O HOH A 934 55.026 28.675 10.894 1.00 53.47 O HETATM 2589 O HOH A 935 51.977 28.324 11.280 1.00 37.02 O HETATM 2590 O HOH A 936 59.701 22.650 14.633 1.00 53.56 O HETATM 2591 O HOH A 937 36.401 6.849 -8.557 1.00 56.41 O HETATM 2592 O HOH A 938 61.416 26.909 -10.858 1.00 84.24 O HETATM 2593 O AHOH A 939 44.641 17.401 12.665 0.98 58.11 O HETATM 2594 O HOH A 940 44.881 10.401 -11.248 1.00 68.33 O HETATM 2595 O HOH A 941 45.321 18.077 16.883 1.00 86.03 O HETATM 2596 O HOH A 942 44.509 19.858 12.069 1.00 53.87 O HETATM 2597 O HOH A 943 27.624 27.818 8.594 1.00 66.88 O HETATM 2598 O HOH A 944 57.430 30.719 7.563 1.00 70.24 O HETATM 2599 O HOH A 945 29.334 23.917 9.100 1.00 55.12 O HETATM 2600 O HOH A 946 58.090 27.147 14.090 1.00 62.87 O HETATM 2601 O HOH A 947 33.148 13.057 16.003 1.00 69.81 O HETATM 2602 O HOH A 948 41.825 30.242 16.402 1.00 66.88 O HETATM 2603 O AHOH A 949 61.140 -1.352 5.135 0.54 31.37 O HETATM 2604 O BHOH A 949 62.251 -1.563 3.759 0.46 42.73 O HETATM 2605 O HOH A 950 53.967 11.790 18.733 1.00 58.64 O HETATM 2606 O HOH A 951 25.038 14.809 -1.865 1.00 53.17 O HETATM 2607 O HOH A 952 32.537 1.411 2.261 1.00 50.96 O HETATM 2608 O HOH A 953 24.859 28.223 8.544 1.00 70.60 O HETATM 2609 O HOH A 954 67.008 20.524 9.008 1.00 64.38 O HETATM 2610 O HOH A 955 36.163 9.298 -8.507 1.00 48.26 O HETATM 2611 O HOH A 956 53.127 -5.237 15.129 1.00 82.72 O HETATM 2612 O HOH A 957 43.003 8.738 -10.588 1.00 62.97 O HETATM 2613 O HOH A 958 55.381 30.543 9.347 1.00 72.84 O HETATM 2614 O HOH A 959 48.461 2.549 -3.853 1.00 55.09 O HETATM 2615 O HOH A 960 41.203 -5.221 8.990 1.00 57.70 O HETATM 2616 O HOH A 961 30.203 23.119 -16.381 1.00 67.43 O HETATM 2617 O HOH A 962 62.722 27.484 10.025 1.00 71.06 O HETATM 2618 O HOH A 963 48.825 -4.608 1.131 1.00 55.05 O HETATM 2619 O HOH A 964 30.257 8.154 -6.595 1.00 57.20 O HETATM 2620 O HOH A 965 38.070 14.325 -19.110 1.00 61.07 O HETATM 2621 O HOH A 966 43.546 12.127 16.107 1.00 59.24 O HETATM 2622 O HOH A 967 26.230 19.418 14.001 1.00 78.29 O HETATM 2623 O HOH A 968 63.618 25.893 -9.297 1.00 81.33 O HETATM 2624 O HOH A 969 60.696 37.859 -2.854 1.00 47.19 O HETATM 2625 O HOH A 970 62.318 20.066 13.197 1.00 62.31 O HETATM 2626 O HOH A 971 38.079 3.138 10.872 1.00 60.17 O HETATM 2627 O HOH A 972 51.740 -8.295 11.301 1.00 94.48 O HETATM 2628 O HOH A 973 57.553 -4.158 5.705 1.00 71.46 O HETATM 2629 O HOH A 974 16.886 13.903 -0.219 1.00 82.39 O HETATM 2630 O HOH A 975 50.708 30.515 10.899 1.00 65.14 O HETATM 2631 O HOH A 976 25.383 6.538 3.680 1.00 68.39 O