Analysis Type: PANTHER Overrepresentation Test (Released 20240226) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.10536401 Released 2024-01-17 Analyzed List: upload_1 (Rattus norvegicus) Reference List: Rattus norvegicus (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Rattus norvegicus - REFLIST (22870) upload_1 (29) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) beta-alanine biosynthetic process (GO:0019483) 2 2 .00 + > 100 1.55E-06 3.28E-04 uracil catabolic process (GO:0006212) 2 2 .00 + > 100 1.55E-06 3.23E-04 thymine catabolic process (GO:0006210) 3 3 .00 + > 100 1.83E-09 1.13E-06 pyrimidine nucleobase catabolic process (GO:0006208) 3 3 .00 + > 100 1.83E-09 1.08E-06 thymine metabolic process (GO:0019859) 3 3 .00 + > 100 1.83E-09 1.04E-06 beta-alanine metabolic process (GO:0019482) 5 4 .01 + > 100 1.04E-11 8.55E-09 uracil metabolic process (GO:0019860) 3 2 .00 + > 100 4.65E-06 8.49E-04 dUMP catabolic process (GO:0046079) 5 3 .01 + > 100 1.83E-08 7.95E-06 dCMP metabolic process (GO:0046063) 5 3 .01 + > 100 1.83E-08 7.73E-06 UMP catabolic process (GO:0046050) 5 3 .01 + > 100 1.83E-08 7.51E-06 dCMP catabolic process (GO:0006249) 5 3 .01 + > 100 1.83E-08 7.31E-06 CMP catabolic process (GO:0006248) 5 3 .01 + > 100 1.83E-08 7.12E-06 dUMP metabolic process (GO:0046078) 6 3 .01 + > 100 3.66E-08 1.35E-05 valine catabolic process (GO:0006574) 4 2 .01 + > 100 9.30E-06 1.64E-03 gamma-aminobutyric acid biosynthetic process (GO:0009449) 6 3 .01 + > 100 3.66E-08 1.32E-05 pyrimidine ribonucleoside monophosphate catabolic process (GO:0009175) 6 3 .01 + > 100 3.66E-08 1.29E-05 nucleobase catabolic process (GO:0046113) 7 3 .01 + > 100 6.39E-08 2.20E-05 pyrimidine deoxyribonucleoside monophosphate catabolic process (GO:0009178) 7 3 .01 + > 100 6.39E-08 2.15E-05 non-proteinogenic amino acid biosynthetic process (GO:0170043) 12 5 .02 + > 100 1.79E-12 2.04E-09 CMP metabolic process (GO:0046035) 8 3 .01 + > 100 1.02E-07 3.21E-05 gamma-aminobutyric acid metabolic process (GO:0009448) 8 3 .01 + > 100 1.02E-07 3.15E-05 pyrimidine ribonucleotide catabolic process (GO:0009222) 8 3 .01 + > 100 1.02E-07 3.08E-05 pyrimidine nucleoside monophosphate catabolic process (GO:0009131) 8 3 .01 + > 100 1.02E-07 3.02E-05 fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) 6 2 .01 + > 100 2.32E-05 3.69E-03 amino-acid betaine biosynthetic process (GO:0006578) 6 2 .01 + > 100 2.32E-05 3.65E-03 glutamate catabolic process (GO:0006538) 6 2 .01 + > 100 2.32E-05 3.61E-03 pyrimidine deoxyribonucleotide catabolic process (GO:0009223) 9 3 .01 + > 100 1.53E-07 4.44E-05 pyrimidine deoxyribonucleoside monophosphate metabolic process (GO:0009176) 9 3 .01 + > 100 1.53E-07 4.35E-05 UMP metabolic process (GO:0046049) 10 3 .01 + > 100 2.19E-07 5.98E-05 valine metabolic process (GO:0006573) 7 2 .01 + > 100 3.25E-05 4.85E-03 ethanol catabolic process (GO:0006068) 11 3 .01 + > 100 3.00E-07 8.07E-05 pyrimidine nucleoside catabolic process (GO:0046135) 8 2 .01 + > 100 4.33E-05 6.39E-03 pyrimidine nucleotide catabolic process (GO:0006244) 12 3 .02 + > 100 4.00E-07 1.04E-04 pyrimidine deoxyribonucleotide metabolic process (GO:0009219) 12 3 .02 + > 100 4.00E-07 1.02E-04 pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) 12 3 .02 + > 100 4.00E-07 1.00E-04 primary alcohol catabolic process (GO:0034310) 13 3 .02 + > 100 5.20E-07 1.28E-04 ethanol metabolic process (GO:0006067) 14 3 .02 + > 100 6.61E-07 1.53E-04 pyrimidine nucleobase metabolic process (GO:0006206) 15 3 .02 + > 100 8.26E-07 1.88E-04 response to caloric restriction (GO:0061771) 10 2 .01 + > 100 6.94E-05 9.68E-03 deoxyribonucleoside monophosphate catabolic process (GO:0009159) 15 3 .02 + > 100 8.26E-07 1.85E-04 pyrimidine nucleoside monophosphate metabolic process (GO:0009129) 16 3 .02 + > 100 1.02E-06 2.21E-04 pyrimidine-containing compound catabolic process (GO:0072529) 22 4 .03 + > 100 1.50E-08 6.93E-06 ribonucleoside monophosphate catabolic process (GO:0009158) 17 3 .02 + > 100 1.23E-06 2.64E-04 pyrimidine nucleoside metabolic process (GO:0006213) 12 2 .02 + > 100 1.02E-04 1.35E-02 aldehyde catabolic process (GO:0046185) 13 2 .02 + > 100 1.20E-04 1.57E-02 nucleoside monophosphate catabolic process (GO:0009125) 20 3 .03 + > 100 2.06E-06 4.23E-04 dicarboxylic acid catabolic process (GO:0043649) 14 2 .02 + > 100 1.40E-04 1.80E-02 deoxyribonucleotide catabolic process (GO:0009264) 22 3 .03 + > 100 2.78E-06 5.62E-04 deoxyribonucleoside monophosphate metabolic process (GO:0009162) 22 3 .03 + > 100 2.78E-06 5.55E-04 deoxyribose phosphate catabolic process (GO:0046386) 22 3 .03 + > 100 2.78E-06 5.47E-04 non-proteinogenic amino acid catabolic process (GO:0170044) 15 2 .02 + > 100 1.61E-04 2.06E-02 pyrimidine ribonucleotide metabolic process (GO:0009218) 24 3 .03 + 98.58 3.64E-06 6.90E-04 nucleoside catabolic process (GO:0009164) 17 2 .02 + 92.78 2.09E-04 2.61E-02 fatty acid beta-oxidation (GO:0006635) 53 6 .07 + 89.28 5.27E-11 3.90E-08 amino-acid betaine metabolic process (GO:0006577) 18 2 .02 + 87.62 2.35E-04 2.89E-02 non-proteinogenic amino acid metabolic process (GO:0170041) 69 7 .09 + 80.00 2.46E-12 2.60E-09 branched-chain amino acid catabolic process (GO:0009083) 20 2 .03 + 78.86 2.91E-04 3.47E-02 nucleobase-containing small molecule catabolic process (GO:0034656) 20 2 .03 + 78.86 2.91E-04 3.44E-02 regulation of dopamine metabolic process (GO:0042053) 21 2 .03 + 75.11 3.21E-04 3.74E-02 fatty acid oxidation (GO:0019395) 77 7 .10 + 71.69 5.45E-12 5.37E-09 pyrimidine nucleotide metabolic process (GO:0006220) 33 3 .04 + 71.69 9.75E-06 1.69E-03 2'-deoxyribonucleotide metabolic process (GO:0009394) 33 3 .04 + 71.69 9.75E-06 1.68E-03 nucleobase metabolic process (GO:0009112) 34 3 .04 + 69.58 1.07E-05 1.79E-03 deoxyribose phosphate metabolic process (GO:0019692) 34 3 .04 + 69.58 1.07E-05 1.77E-03 regulation of catecholamine metabolic process (GO:0042069) 23 2 .03 + 68.58 3.86E-04 4.43E-02 cellular aldehyde metabolic process (GO:0006081) 58 5 .07 + 67.98 9.97E-09 5.08E-06 alcohol catabolic process (GO:0046164) 35 3 .04 + 67.60 1.17E-05 1.92E-03 deoxyribonucleotide metabolic process (GO:0009262) 35 3 .04 + 67.60 1.17E-05 1.90E-03 lipid oxidation (GO:0034440) 83 7 .11 + 66.51 9.37E-12 8.15E-09 amino acid biosynthetic process (GO:0008652) 60 5 .08 + 65.72 1.19E-08 5.84E-06 branched-chain amino acid metabolic process (GO:0009081) 24 2 .03 + 65.72 4.21E-04 4.79E-02 fatty acid catabolic process (GO:0009062) 81 6 .10 + 58.42 7.28E-10 4.68E-07 pyrimidine-containing compound metabolic process (GO:0072527) 54 4 .07 + 58.42 6.31E-07 1.48E-04 ribonucleoside monophosphate metabolic process (GO:0009161) 47 3 .06 + 50.34 2.86E-05 4.41E-03 monocarboxylic acid catabolic process (GO:0072329) 104 6 .13 + 45.50 3.33E-09 1.83E-06 organic hydroxy compound catabolic process (GO:1901616) 57 3 .07 + 41.51 5.12E-05 7.35E-03 organic acid catabolic process (GO:0016054) 209 11 .27 + 41.51 8.54E-16 1.40E-12 carboxylic acid catabolic process (GO:0046395) 209 11 .27 + 41.51 8.54E-16 1.26E-12 small molecule catabolic process (GO:0044282) 305 16 .39 + 41.37 3.92E-23 5.79E-19 amino acid catabolic process (GO:0009063) 101 5 .13 + 39.04 1.66E-07 4.63E-05 alpha-amino acid catabolic process (GO:1901606) 82 4 .10 + 38.47 3.40E-06 6.54E-04 nucleoside monophosphate metabolic process (GO:0009123) 63 3 .08 + 37.55 6.92E-05 9.73E-03 lipid modification (GO:0030258) 150 7 .19 + 36.80 6.27E-10 4.21E-07 ribonucleotide catabolic process (GO:0009261) 86 4 .11 + 36.68 4.12E-06 7.71E-04 primary alcohol metabolic process (GO:0034308) 86 4 .11 + 36.68 4.12E-06 7.61E-04 response to progesterone (GO:0032570) 74 3 .09 + 31.97 1.12E-04 1.48E-02 nucleotide catabolic process (GO:0009166) 103 4 .13 + 30.63 8.45E-06 1.50E-03 nucleoside phosphate catabolic process (GO:1901292) 109 4 .14 + 28.94 1.06E-05 1.80E-03 amino acid metabolic process (GO:0006520) 249 9 .32 + 28.50 1.54E-11 1.20E-08 response to cocaine (GO:0042220) 85 3 .11 + 27.83 1.69E-04 2.13E-02 cellular lipid catabolic process (GO:0044242) 171 6 .22 + 27.67 6.59E-08 2.16E-05 carboxylic acid biosynthetic process (GO:0046394) 235 7 .30 + 23.49 1.42E-08 6.79E-06 organic acid biosynthetic process (GO:0016053) 239 7 .30 + 23.10 1.60E-08 7.16E-06 organophosphate catabolic process (GO:0046434) 158 4 .20 + 19.97 4.55E-05 6.66E-03 fatty acid metabolic process (GO:0006631) 325 8 .41 + 19.41 5.05E-09 2.67E-06 carboxylic acid metabolic process (GO:0019752) 716 17 .91 + 18.72 8.09E-19 5.98E-15 oxoacid metabolic process (GO:0043436) 729 17 .92 + 18.39 1.09E-18 5.39E-15 organic acid metabolic process (GO:0006082) 740 17 .94 + 18.12 1.41E-18 5.20E-15 lipid catabolic process (GO:0016042) 263 6 .33 + 17.99 8.31E-07 1.83E-04 carbohydrate derivative catabolic process (GO:1901136) 177 4 .22 + 17.82 7.08E-05 9.78E-03 monocarboxylic acid metabolic process (GO:0032787) 487 11 .62 + 17.81 8.93E-12 8.25E-09 alpha-amino acid metabolic process (GO:1901605) 189 4 .24 + 16.69 9.13E-05 1.23E-02 cellular catabolic process (GO:0044248) 889 17 1.13 + 15.08 3.04E-17 7.50E-14 heterocycle catabolic process (GO:0046700) 289 5 .37 + 13.64 2.88E-05 4.39E-03 cellular nitrogen compound catabolic process (GO:0044270) 290 5 .37 + 13.60 2.93E-05 4.42E-03 small molecule biosynthetic process (GO:0044283) 407 7 .52 + 13.56 5.98E-07 1.42E-04 nucleobase-containing compound catabolic process (GO:0034655) 254 4 .32 + 12.42 2.84E-04 3.41E-02 organic cyclic compound catabolic process (GO:1901361) 337 5 .43 + 11.70 5.99E-05 8.51E-03 small molecule metabolic process (GO:0044281) 1362 20 1.73 + 11.58 1.65E-18 4.87E-15 organic substance catabolic process (GO:1901575) 1339 19 1.70 + 11.19 3.86E-17 8.16E-14 response to steroid hormone (GO:0048545) 449 6 .57 + 10.54 1.79E-05 2.88E-03 catabolic process (GO:0009056) 1553 19 1.97 + 9.65 5.99E-16 1.11E-12 nucleobase-containing small molecule metabolic process (GO:0055086) 454 5 .58 + 8.69 2.42E-04 2.95E-02 organonitrogen compound catabolic process (GO:1901565) 912 10 1.16 + 8.65 9.72E-08 3.12E-05 response to oxygen levels (GO:0070482) 493 5 .63 + 8.00 3.53E-04 4.08E-02 cellular lipid metabolic process (GO:0044255) 804 8 1.02 + 7.85 5.02E-06 9.04E-04 lipid metabolic process (GO:0006629) 1060 10 1.34 + 7.44 3.92E-07 1.04E-04 response to xenobiotic stimulus (GO:0009410) 647 6 .82 + 7.31 1.36E-04 1.77E-02 organonitrogen compound biosynthetic process (GO:1901566) 1029 9 1.30 + 6.90 3.23E-06 6.29E-04 response to nutrient levels (GO:0031667) 706 6 .90 + 6.70 2.19E-04 2.72E-02 response to extracellular stimulus (GO:0009991) 736 6 .93 + 6.43 2.74E-04 3.32E-02 response to hormone (GO:0009725) 1068 7 1.35 + 5.17 3.00E-04 3.52E-02 organic substance metabolic process (GO:0071704) 5597 27 7.10 + 3.80 7.08E-15 9.51E-12 organonitrogen compound metabolic process (GO:1901564) 3411 16 4.33 + 3.70 5.61E-07 1.36E-04 cellular metabolic process (GO:0044237) 4846 22 6.14 + 3.58 4.64E-10 3.27E-07 metabolic process (GO:0008152) 6079 27 7.71 + 3.50 6.27E-14 7.72E-11 primary metabolic process (GO:0044238) 5201 21 6.60 + 3.18 1.85E-08 7.01E-06 nitrogen compound metabolic process (GO:0006807) 4731 16 6.00 + 2.67 4.59E-05 6.66E-03 biological_process (GO:0008150) 13583 27 17.22 + 1.57 8.19E-05 1.12E-02 Unclassified (UNCLASSIFIED) 9287 2 11.78 - .17 8.19E-05 1.11E-02