LOCUS       NC_003098            2038615 bp    DNA     circular CON 16-DEC-2014
DEFINITION  Streptococcus pneumoniae R6 chromosome, complete genome.
ACCESSION   NC_003098
VERSION     NC_003098.1  GI:15902044
DBLINK      BioProject: PRJNA57859
KEYWORDS    RefSeq.
SOURCE      Streptococcus pneumoniae R6
  ORGANISM  Streptococcus pneumoniae R6
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2038615)
  AUTHORS   Hoskins,J.A., Alborn,W. Jr., Arnold,J., Blaszczak,L., Burgett,S.,
            DeHoff,B.S., Estrem,S., Fritz,L., Fu,D.-J., Fuller,W., Geringer,C.,
            Gilmour,R., Glass,J.S., Khoja,H., Kraft,A., LaGace,R.,
            LeBlanc,D.J., Lee,L.N., Lefkowitz,E.J., Lu,J., Matsushima,P.,
            McAhren,S., McHenney,M., McLeaster,K., Mundy,C., Nicas,T.I.,
            Norris,F.H., O'Gara,M., Peery,R., Robertson,G.T., Rockey,P.,
            Sun,P.-M., Winkler,M.E., Yang,Y., Young-Bellido,M., Zhao,G.,
            Zook,C., Baltz,R.H., Jaskunas,S.Richard., Rosteck,P.R. Jr.,
            Skatrud,P.L. and Glass,J.I.
  TITLE     Genome of the bacterium Streptococcus pneumoniae strain R6
  JOURNAL   J. Bacteriol. 183 (19), 5709-5717 (2001)
   PUBMED   11544234
REFERENCE   2  (bases 1 to 2038615)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2001) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   3  (bases 1 to 2038615)
  AUTHORS   Hoskins,J.A., Alborn,W. Jr., Arnold,J., Blaszczak,L., Burgett,S.,
            DeHoff,B.S., Estrem,S., Fritz,L., Fu,D.-J., Fuller,W., Geringer,C.,
            Gilmour,R., Glass,J.S., Hann,A., Khoja,H., Kraft,A., LaGace,R.,
            LeBlanc,D.J., Lee,L.N., Lefkowitz,E.J., Lu,J., Matsushima,P.,
            McAhren,S., McHenney,M., McLeaster,K., Mundy,C., Nicas,T.I.,
            Norris,F.H., O'Gara,M., Peery,R., Robertson,G.T., Rockey,P.,
            Sun,P.-M., Winkler,M.E., Yang,Y., Young-Bellido,M., Zhao,G.,
            Zook,C., Baltz,R.H., Jaskunas,S.Richard., Rosteck,P.R. Jr.,
            Skatrud,P.L. and Glass,J.I.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-JUL-2001) Infectious Diseases Research, Eli Lilly and
            Company, Lilly Research Labs, Indianapolis, IN 46285-0438, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AE007317.
            RefSeq Category: Reference Genome
                        UPR: UniProt Genome
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..2038615
                     /organism="Streptococcus pneumoniae R6"
                     /mol_type="genomic DNA"
                     /strain="R6"
                     /db_xref="taxon:171101"
     gene            1..1362
                     /gene="dnaA"
                     /locus_tag="spr0001"
                     /db_xref="GeneID:932985"
     CDS             1..1362
                     /gene="dnaA"
                     /locus_tag="spr0001"
                     /note="binds to the dnaA-box as an ATP-bound complex at
                     the origin of replication during the initiation of
                     chromosomal replication; can also affect transcription of
                     multiple genes including itself."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiation protein"
                     /protein_id="NP_357595.1"
                     /db_xref="GI:15902045"
                     /db_xref="GeneID:932985"
     gene            1521..2657
                     /gene="dnaN"
                     /locus_tag="spr0002"
                     /db_xref="GeneID:933376"
     CDS             1521..2657
                     /gene="dnaN"
                     /locus_tag="spr0002"
                     /EC_number="2.7.7.7"
                     /note="binds the polymerase to DNA and acts as a sliding
                     clamp"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="NP_357596.1"
                     /db_xref="GI:15902046"
                     /db_xref="GeneID:933376"
     gene            2722..2916
                     /locus_tag="spr0003"
                     /db_xref="GeneID:932878"
     CDS             2722..2916
                     /locus_tag="spr0003"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357597.1"
                     /db_xref="GI:15902047"
                     /db_xref="GeneID:932878"
     gene            3000..4115
                     /locus_tag="spr0004"
                     /gene_synonym="ychF"
                     /db_xref="GeneID:933428"
     CDS             3000..4115
                     /locus_tag="spr0004"
                     /gene_synonym="ychF"
                     /note="translation-associated GTPase; the crystal
                     structure of the Haemophilus influenzae YchF protein
                     showed similarity to the yeast structure (PDB: 1NI3);
                     fluorescence spectroscopy revealed nucleic acid binding;
                     the yeast protein YBR025c interacts with the translation
                     elongation factor eEF1"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-dependent nucleic acid-binding protein EngD"
                     /protein_id="NP_357598.1"
                     /db_xref="GI:15902048"
                     /db_xref="GeneID:933428"
     gene            4186..4755
                     /gene="pth"
                     /locus_tag="spr0005"
                     /db_xref="GeneID:933315"
     CDS             4186..4755
                     /gene="pth"
                     /locus_tag="spr0005"
                     /EC_number="3.1.1.29"
                     /note="Enables the recycling of peptidyl-tRNAs produced at
                     termination of translation"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-tRNA hydrolase"
                     /protein_id="NP_357599.1"
                     /db_xref="GI:15902049"
                     /db_xref="GeneID:933315"
     gene            4756..8265
                     /gene="mfd"
                     /locus_tag="spr0006"
                     /db_xref="GeneID:933199"
     CDS             4756..8265
                     /gene="mfd"
                     /locus_tag="spr0006"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="NP_357600.1"
                     /db_xref="GI:15902050"
                     /db_xref="GeneID:933199"
     gene            8323..8589
                     /locus_tag="spr0007"
                     /db_xref="GeneID:933324"
     CDS             8323..8589
                     /locus_tag="spr0007"
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein"
                     /protein_id="NP_357601.1"
                     /db_xref="GI:15902051"
                     /db_xref="GeneID:933324"
     gene            8582..8950
                     /locus_tag="spr0008"
                     /db_xref="GeneID:933400"
     CDS             8582..8950
                     /locus_tag="spr0008"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357602.1"
                     /db_xref="GI:15902052"
                     /db_xref="GeneID:933400"
     gene            9001..10338
                     /locus_tag="spr0009"
                     /db_xref="GeneID:933406"
     CDS             9001..10338
                     /locus_tag="spr0009"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357603.1"
                     /db_xref="GI:15902053"
                     /db_xref="GeneID:933406"
     gene            10335..11612
                     /locus_tag="spr0010"
                     /db_xref="GeneID:933448"
     CDS             10335..11612
                     /locus_tag="spr0010"
                     /note="cell cycle protein of the MesJ/Ycf62 family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357604.1"
                     /db_xref="GI:15902054"
                     /db_xref="GeneID:933448"
     gene            11616..12158
                     /gene="hgt"
                     /locus_tag="spr0011"
                     /db_xref="GeneID:933767"
     CDS             11616..12158
                     /gene="hgt"
                     /locus_tag="spr0011"
                     /EC_number="2.4.2.8"
                     /note="Catalyzes the salvage synthesis of
                     inosine-5'-monophosphate (IMP) and
                     guanosine-5'-monophosphate (GMP) from the purine bases
                     hypoxanthine and guanine, respectively"
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine-guanine phosphoribosyltransferase"
                     /protein_id="NP_357605.1"
                     /db_xref="GI:15902055"
                     /db_xref="GeneID:933767"
     gene            12174..14132
                     /gene="ftsH"
                     /locus_tag="spr0012"
                     /db_xref="GeneID:933698"
     CDS             12174..14132
                     /gene="ftsH"
                     /locus_tag="spr0012"
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsH"
                     /protein_id="NP_357606.1"
                     /db_xref="GI:15902056"
                     /db_xref="GeneID:933698"
     gene            14254..14733
                     /gene="comX1"
                     /locus_tag="spr0013"
                     /db_xref="GeneID:933686"
     CDS             14254..14733
                     /gene="comX1"
                     /locus_tag="spr0013"
                     /note="sigma factor"
                     /codon_start=1
                     /transl_table=11
                     /product="competence-specific global transcription
                     modulator"
                     /protein_id="NP_357607.1"
                     /db_xref="GI:15902057"
                     /db_xref="GeneID:933686"
     gene            14827..14898
                     /gene="tRNA-Glu1"
                     /locus_tag="sprt01"
                     /db_xref="GeneID:933466"
     tRNA            14827..14898
                     /gene="tRNA-Glu1"
                     /locus_tag="sprt01"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:933466"
     gene            15161..16674
                     /gene="rRNA_16S-1"
                     /locus_tag="sprr01"
                     /db_xref="GeneID:933447"
     rRNA            15161..16674
                     /gene="rRNA_16S-1"
                     /locus_tag="sprr01"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:933447"
     gene            16748..16820
                     /gene="tRNA-Ala1"
                     /locus_tag="sprt02"
                     /db_xref="GeneID:933675"
     tRNA            16748..16820
                     /gene="tRNA-Ala1"
                     /locus_tag="sprt02"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:933675"
     gene            16945..19846
                     /gene="rRNA_23S-1"
                     /locus_tag="sprr02"
                     /db_xref="GeneID:934056"
     rRNA            16945..19846
                     /gene="rRNA_23S-1"
                     /locus_tag="sprr02"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:934056"
     gene            19924..20038
                     /gene="rRNA_5S-1"
                     /locus_tag="sprr03"
                     /db_xref="GeneID:933458"
     rRNA            19924..20038
                     /gene="rRNA_5S-1"
                     /locus_tag="sprr03"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:933458"
     gene            20044..20117
                     /gene="tRNA-Asn1"
                     /locus_tag="sprt03"
                     /db_xref="GeneID:932819"
     tRNA            20044..20117
                     /gene="tRNA-Asn1"
                     /locus_tag="sprt03"
                     /product="tRNA-Asn"
                     /db_xref="GeneID:932819"
     gene            20207..20554
                     /gene="transposase_A"
                     /locus_tag="spr0014"
                     /db_xref="GeneID:933716"
     CDS             20207..20554
                     /gene="transposase_A"
                     /locus_tag="spr0014"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_357608.1"
                     /db_xref="GI:15902058"
                     /db_xref="GeneID:933716"
     gene            20733..21071
                     /gene="transposase_B"
                     /locus_tag="spr0016"
                     /db_xref="GeneID:932809"
     CDS             20733..21071
                     /gene="transposase_B"
                     /locus_tag="spr0016"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_357610.1"
                     /db_xref="GI:15902060"
                     /db_xref="GeneID:932809"
     gene            complement(21106..21422)
                     /gene="IS1167-truncation"
                     /locus_tag="spr0017"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933668"
     gene            complement(21455..21604)
                     /gene="IS1167-truncation"
                     /locus_tag="spr0018"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933147"
     gene            22162..22404
                     /locus_tag="spr0020"
                     /db_xref="GeneID:932833"
     CDS             22162..22404
                     /locus_tag="spr0020"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357614.1"
                     /db_xref="GI:15902064"
                     /db_xref="GeneID:932833"
     gene            22635..23921
                     /gene="purA"
                     /locus_tag="spr0021"
                     /db_xref="GeneID:933413"
     CDS             22635..23921
                     /gene="purA"
                     /locus_tag="spr0021"
                     /EC_number="6.3.4.4"
                     /note="catalyzes the formation of
                     N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine
                     monophosphate and GTP in AMP biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthetase"
                     /protein_id="NP_357615.1"
                     /db_xref="GI:15902065"
                     /db_xref="GeneID:933413"
     gene            24122..24589
                     /locus_tag="spr0022"
                     /db_xref="GeneID:933408"
     CDS             24122..24589
                     /locus_tag="spr0022"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase"
                     /protein_id="NP_357616.1"
                     /db_xref="GI:15902066"
                     /db_xref="GeneID:933408"
     gene            24631..24815
                     /gene="scRNA"
                     /locus_tag="sprs01"
                     /db_xref="GeneID:933335"
     ncRNA           24631..24815
                     /ncRNA_class="scRNA"
                     /gene="scRNA"
                     /locus_tag="sprs01"
                     /db_xref="GeneID:933335"
     gene            24776..25219
                     /gene="dut"
                     /locus_tag="spr0023"
                     /db_xref="GeneID:933917"
     CDS             24776..25219
                     /gene="dut"
                     /locus_tag="spr0023"
                     /EC_number="3.6.1.23"
                     /note="catalyzes the formation of dUMP from dUTP"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyuridine 5'-triphosphate
                     nucleotidohydrolase"
                     /protein_id="NP_357617.1"
                     /db_xref="GI:15902067"
                     /db_xref="GeneID:933917"
     gene            25158..25736
                     /locus_tag="spr0024"
                     /db_xref="GeneID:933009"
     CDS             25158..25736
                     /locus_tag="spr0024"
                     /note="Similar to phosphoglycerate mutase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357618.1"
                     /db_xref="GI:15902068"
                     /db_xref="GeneID:933009"
     gene            25849..27111
                     /gene="radA"
                     /locus_tag="spr0025"
                     /db_xref="GeneID:933443"
     CDS             25849..27111
                     /gene="radA"
                     /locus_tag="spr0025"
                     /note="Sms; stabilizes the strand-invasion intermediate
                     during the DNA repair; involved in recombination of donor
                     DNA and plays an important role in DNA damage repair after
                     exposure to mutagenic agents"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="NP_357619.1"
                     /db_xref="GI:15902069"
                     /db_xref="GeneID:933443"
     gene            27115..27681
                     /locus_tag="spr0026"
                     /db_xref="GeneID:933190"
     CDS             27115..27681
                     /locus_tag="spr0026"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357620.1"
                     /db_xref="GI:15902070"
                     /db_xref="GeneID:933190"
     gene            27706..28365
                     /locus_tag="spr0027"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933470"
     gene            28583..29602
                     /gene="prsA"
                     /locus_tag="spr0028"
                     /db_xref="GeneID:932853"
     CDS             28583..29602
                     /gene="prsA"
                     /locus_tag="spr0028"
                     /EC_number="2.7.6.1"
                     /note="catalyzes the formation of 5-phospho-alpha-D-ribose
                     1-phosphate from D-ribose 5-phosphate and ATP"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="NP_357622.1"
                     /db_xref="GI:15902072"
                     /db_xref="GeneID:932853"
     gene            complement(30143..30481)
                     /locus_tag="spr0030"
                     /db_xref="GeneID:933421"
     CDS             complement(30143..30481)
                     /locus_tag="spr0030"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357624.1"
                     /db_xref="GI:15902074"
                     /db_xref="GeneID:933421"
     gene            complement(30700..31053)
                     /locus_tag="spr0031"
                     /db_xref="GeneID:933179"
     CDS             complement(30700..31053)
                     /locus_tag="spr0031"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357625.1"
                     /db_xref="GI:15902075"
                     /db_xref="GeneID:933179"
     repeat_region   complement(31068..31174)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            31306..33939
                     /gene="polA"
                     /locus_tag="spr0032"
                     /db_xref="GeneID:933214"
     CDS             31306..33939
                     /gene="polA"
                     /locus_tag="spr0032"
                     /EC_number="2.7.7.7"
                     /note="has 3'-5' exonuclease, 5'-3' exonuclease and
                     5'-3'polymerase activities, primarily functions to fill
                     gaps during DNA replication and repair"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="NP_357626.1"
                     /db_xref="GI:15902076"
                     /db_xref="GeneID:933214"
     gene            34024..34461
                     /locus_tag="spr0033"
                     /db_xref="GeneID:933816"
     CDS             34024..34461
                     /locus_tag="spr0033"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357627.1"
                     /db_xref="GI:15902077"
                     /db_xref="GeneID:933816"
     repeat_region   complement(34493..34650)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(34652..35674)
                     /locus_tag="spr0034"
                     /db_xref="GeneID:933827"
     CDS             complement(34652..35674)
                     /locus_tag="spr0034"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357628.1"
                     /db_xref="GI:15902078"
                     /db_xref="GeneID:933827"
     gene            35811..36980
                     /gene="aspC"
                     /locus_tag="spr0035"
                     /db_xref="GeneID:932812"
     CDS             35811..36980
                     /gene="aspC"
                     /locus_tag="spr0035"
                     /EC_number="2.6.1.1"
                     /note="catalyzes the transamination of the aromatic amino
                     acid forming a ketoacid; first step in aromatic amino acid
                     degradation in lactococci"
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid aminotransferase"
                     /protein_id="NP_357629.1"
                     /db_xref="GI:15902079"
                     /db_xref="GeneID:932812"
     gene            36977..37747
                     /gene="recO"
                     /locus_tag="spr0036"
                     /db_xref="GeneID:933442"
     CDS             36977..37747
                     /gene="recO"
                     /locus_tag="spr0036"
                     /note="involved in DNA repair and RecFOR pathway
                     recombination; RecFOR proteins displace ssDNA-binding
                     protein and facilitate the production of RecA-coated
                     ssDNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="NP_357630.1"
                     /db_xref="GI:15902080"
                     /db_xref="GeneID:933442"
     gene            37744..38736
                     /gene="plsX"
                     /locus_tag="spr0037"
                     /db_xref="GeneID:932937"
     CDS             37744..38736
                     /gene="plsX"
                     /locus_tag="spr0037"
                     /note="involved in acylation of glycerol-3-phosphate to
                     form 1-acyl-glycerol-3 phosphate for use in phospholipid
                     biosynthesis; functions with PlsY"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate acyltransferase PlsX"
                     /protein_id="NP_357631.1"
                     /db_xref="GI:15902081"
                     /db_xref="GeneID:932937"
     gene            38742..38975
                     /gene="acpP"
                     /locus_tag="spr0038"
                     /db_xref="GeneID:933946"
     CDS             38742..38975
                     /gene="acpP"
                     /locus_tag="spr0038"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="NP_357632.1"
                     /db_xref="GI:15902082"
                     /db_xref="GeneID:933946"
     gene            39514..39744
                     /gene="thmA"
                     /locus_tag="spr0040"
                     /db_xref="GeneID:932910"
     CDS             39514..39744
                     /gene="thmA"
                     /locus_tag="spr0040"
                     /codon_start=1
                     /transl_table=11
                     /product="amphipathic pore-forming protein"
                     /protein_id="NP_357634.1"
                     /db_xref="GI:15902084"
                     /db_xref="GeneID:932910"
     gene            complement(40224..40991)
                     /gene="IS1167"
                     /locus_tag="spr0041"
                     /db_xref="GeneID:933120"
     CDS             complement(40224..40991)
                     /gene="IS1167"
                     /locus_tag="spr0041"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_357635.1"
                     /db_xref="GI:15902085"
                     /db_xref="GeneID:933120"
     gene            complement(40982..41500)
                     /gene="IS1167"
                     /locus_tag="spr0042"
                     /db_xref="GeneID:933460"
     CDS             complement(40982..41500)
                     /gene="IS1167"
                     /locus_tag="spr0042"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_357636.1"
                     /db_xref="GI:15902086"
                     /db_xref="GeneID:933460"
     repeat_region   41732..41882
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            41902..44055
                     /gene="comA"
                     /locus_tag="spr0043"
                     /db_xref="GeneID:933354"
     CDS             41902..44055
                     /gene="comA"
                     /locus_tag="spr0043"
                     /note="Competence induced protein ComA, with ComB is
                     responsible for secretion of CSP"
                     /codon_start=1
                     /transl_table=11
                     /product="competence factor transporting ATP-binding
                     protein/permease ComA"
                     /protein_id="NP_357637.1"
                     /db_xref="GI:15902087"
                     /db_xref="GeneID:933354"
     gene            44068..45417
                     /gene="comB"
                     /locus_tag="spr0044"
                     /db_xref="GeneID:933217"
     CDS             44068..45417
                     /gene="comB"
                     /locus_tag="spr0044"
                     /note="Competence induced protein ComB, with ComA is
                     responsible for secretion of CSP"
                     /codon_start=1
                     /transl_table=11
                     /product="competence factor transport protein ComB"
                     /protein_id="NP_357638.1"
                     /db_xref="GI:15902088"
                     /db_xref="GeneID:933217"
     gene            45545..46294
                     /gene="purC"
                     /locus_tag="spr0045"
                     /db_xref="GeneID:933370"
     CDS             45545..46294
                     /gene="purC"
                     /locus_tag="spr0045"
                     /EC_number="6.3.2.6"
                     /note="catalyzes the formation of
                     (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-
                     carboxamido)succinate from
                     5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and
                     L-aspartate in purine biosynthesis; SAICAR synthase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole-succinocarboxamide
                     synthase"
                     /protein_id="NP_357639.1"
                     /db_xref="GI:15902089"
                     /db_xref="GeneID:933370"
     gene            46493..50221
                     /gene="purL"
                     /locus_tag="spr0046"
                     /db_xref="GeneID:933136"
     CDS             46493..50221
                     /gene="purL"
                     /locus_tag="spr0046"
                     /EC_number="6.3.5.3"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="NP_357640.1"
                     /db_xref="GI:15902090"
                     /db_xref="GeneID:933136"
     gene            50314..51756
                     /gene="purF"
                     /locus_tag="spr0047"
                     /db_xref="GeneID:933435"
     CDS             50314..51756
                     /gene="purF"
                     /locus_tag="spr0047"
                     /EC_number="2.4.2.14"
                     /note="Catalyzes first step of the de novo purine
                     nucleotide biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="NP_357641.1"
                     /db_xref="GI:15902091"
                     /db_xref="GeneID:933435"
     gene            51793..52815
                     /gene="purM"
                     /locus_tag="spr0048"
                     /db_xref="GeneID:933451"
     CDS             51793..52815
                     /gene="purM"
                     /locus_tag="spr0048"
                     /EC_number="6.3.3.1"
                     /note="catalyzes the formation of
                     1-(5-phosphoribosyl)-5-aminoimidazole from
                     2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in
                     purine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole synthetase"
                     /protein_id="NP_357642.1"
                     /db_xref="GI:15902092"
                     /db_xref="GeneID:933451"
     gene            52812..53357
                     /gene="purN"
                     /locus_tag="spr0049"
                     /db_xref="GeneID:933927"
     CDS             52812..53357
                     /gene="purN"
                     /locus_tag="spr0049"
                     /EC_number="2.1.2.2"
                     /note="glycinamide ribonucleotide transformylase; GAR
                     Tfase; catalyzes the synthesis of
                     5'-phosphoribosylformylglycinamide from
                     5'-phosphoribosylglycinamide and
                     10-formyltetrahydrofolate; PurN requires formyl folate for
                     the reaction unlike PurT which uses formate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="NP_357643.1"
                     /db_xref="GI:15902093"
                     /db_xref="GeneID:933927"
     gene            53441..53950
                     /gene="vanZ"
                     /locus_tag="spr0050"
                     /db_xref="GeneID:933039"
     CDS             53441..53950
                     /gene="vanZ"
                     /locus_tag="spr0050"
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ protein"
                     /protein_id="NP_357644.1"
                     /db_xref="GI:15902094"
                     /db_xref="GeneID:933039"
     gene            53954..55522
                     /gene="purH"
                     /locus_tag="spr0051"
                     /db_xref="GeneID:933467"
     CDS             53954..55522
                     /gene="purH"
                     /locus_tag="spr0051"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /note="involved in de novo purine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="NP_357645.1"
                     /db_xref="GI:15902095"
                     /db_xref="GeneID:933467"
     gene            55644..56906
                     /gene="purD"
                     /locus_tag="spr0052"
                     /db_xref="GeneID:933188"
     CDS             55644..56906
                     /gene="purD"
                     /locus_tag="spr0052"
                     /EC_number="6.3.4.13"
                     /note="catalyzes the formation of
                     N(1)-(5-phospho-D-ribosyl)glycinamide from
                     5-phospho-D-ribosylamine and glycine in purine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="NP_357646.1"
                     /db_xref="GI:15902096"
                     /db_xref="GeneID:933188"
     gene            56979..57146
                     /locus_tag="spr0052a"
                     /db_xref="GeneID:17374503"
     CDS             56979..57146
                     /locus_tag="spr0052a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719798.1"
                     /db_xref="GI:555247344"
                     /db_xref="GeneID:17374503"
     gene            57276..57797
                     /gene="purE"
                     /locus_tag="spr0053"
                     /db_xref="GeneID:933469"
     CDS             57276..57797
                     /gene="purE"
                     /locus_tag="spr0053"
                     /EC_number="4.1.1.21"
                     /note="Catalyzes a step in the de novo purine nucleotide
                     biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase
                     catalytic subunit"
                     /protein_id="NP_357647.1"
                     /db_xref="GI:15902097"
                     /db_xref="GeneID:933469"
     gene            57724..58875
                     /gene="purK"
                     /locus_tag="spr0054"
                     /db_xref="GeneID:933386"
     CDS             57724..58875
                     /gene="purK"
                     /locus_tag="spr0054"
                     /EC_number="4.1.1.21"
                     /note="With PurE catalyzes the conversion of
                     aminoimidazole ribonucleotide to carboxyaminoimidazole
                     ribonucleotide in the de novo purine nucleotide
                     biosynthetic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase ATPase
                     subunit"
                     /protein_id="NP_357648.1"
                     /db_xref="GI:15902098"
                     /db_xref="GeneID:933386"
     gene            58885..59112
                     /locus_tag="spr0055"
                     /db_xref="GeneID:933457"
     CDS             58885..59112
                     /locus_tag="spr0055"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357649.1"
                     /db_xref="GI:15902099"
                     /db_xref="GeneID:933457"
     gene            59175..60473
                     /gene="purB"
                     /locus_tag="spr0056"
                     /db_xref="GeneID:933426"
     CDS             59175..60473
                     /gene="purB"
                     /locus_tag="spr0056"
                     /EC_number="4.3.2.2"
                     /note="Catalyzes two discrete reactions in the de novo
                     synthesis of purines: the cleavage of adenylosuccinate and
                     succinylaminoimidazole carboxamide ribotide"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="NP_357650.1"
                     /db_xref="GI:15902100"
                     /db_xref="GeneID:933426"
     gene            complement(60528..64466)
                     /gene="strH"
                     /locus_tag="spr0057"
                     /db_xref="GeneID:933411"
     CDS             complement(60528..64466)
                     /gene="strH"
                     /locus_tag="spr0057"
                     /EC_number="3.2.1.52"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="NP_357651.1"
                     /db_xref="GI:15902101"
                     /db_xref="GeneID:933411"
     gene            complement(64781..65539)
                     /locus_tag="spr0058"
                     /db_xref="GeneID:933173"
     CDS             complement(64781..65539)
                     /locus_tag="spr0058"
                     /note="Similar to transcriptional regulator (GntR family)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357652.1"
                     /db_xref="GI:15902102"
                     /db_xref="GeneID:933173"
     gene            65845..67632
                     /gene="bgaC"
                     /locus_tag="spr0059"
                     /db_xref="GeneID:934033"
     CDS             65845..67632
                     /gene="bgaC"
                     /locus_tag="spr0059"
                     /EC_number="3.2.1.23"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase 3"
                     /protein_id="NP_357653.1"
                     /db_xref="GI:15902103"
                     /db_xref="GeneID:934033"
     gene            67629..68105
                     /gene="PTS-EIIB"
                     /locus_tag="spr0060"
                     /db_xref="GeneID:933462"
     CDS             67629..68105
                     /gene="PTS-EIIB"
                     /locus_tag="spr0060"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_357654.1"
                     /db_xref="GI:15902104"
                     /db_xref="GeneID:933462"
     gene            68133..69038
                     /gene="PTS-EIIC"
                     /locus_tag="spr0061"
                     /db_xref="GeneID:933468"
     CDS             68133..69038
                     /gene="PTS-EIIC"
                     /locus_tag="spr0061"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_357655.1"
                     /db_xref="GI:15902105"
                     /db_xref="GeneID:933468"
     gene            69010..69840
                     /gene="PTS-EIID"
                     /locus_tag="spr0062"
                     /db_xref="GeneID:933330"
     CDS             69010..69840
                     /gene="PTS-EIID"
                     /locus_tag="spr0062"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IID"
                     /protein_id="NP_357656.1"
                     /db_xref="GI:15902106"
                     /db_xref="GeneID:933330"
     gene            69847..70251
                     /gene="PTS-EII"
                     /locus_tag="spr0063"
                     /db_xref="GeneID:932847"
     CDS             69847..70251
                     /gene="PTS-EII"
                     /locus_tag="spr0063"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_357657.1"
                     /db_xref="GI:15902107"
                     /db_xref="GeneID:932847"
     repeat_region   70249..70421
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            70549..71715
                     /gene="agaS"
                     /locus_tag="spr0064"
                     /db_xref="GeneID:932790"
     CDS             70549..71715
                     /gene="agaS"
                     /locus_tag="spr0064"
                     /EC_number="5.3.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar isomerase domain-containing protein"
                     /protein_id="NP_357658.1"
                     /db_xref="GI:15902108"
                     /db_xref="GeneID:932790"
     gene            71831..72868
                     /gene="galM"
                     /locus_tag="spr0065"
                     /db_xref="GeneID:932955"
     CDS             71831..72868
                     /gene="galM"
                     /locus_tag="spr0065"
                     /EC_number="5.1.3.3"
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="NP_357659.1"
                     /db_xref="GI:15902109"
                     /db_xref="GeneID:932955"
     gene            73075..73929
                     /locus_tag="spr0066"
                     /db_xref="GeneID:932795"
     CDS             73075..73929
                     /locus_tag="spr0066"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357660.1"
                     /db_xref="GI:15902110"
                     /db_xref="GeneID:932795"
     gene            74079..74336
                     /locus_tag="spr0067"
                     /db_xref="GeneID:932792"
     CDS             74079..74336
                     /locus_tag="spr0067"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357661.1"
                     /db_xref="GI:15902111"
                     /db_xref="GeneID:932792"
     repeat_region   74552..74747
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            75311..76075
                     /locus_tag="spr0068"
                     /db_xref="GeneID:932794"
     CDS             75311..76075
                     /locus_tag="spr0068"
                     /note="Similar to uridine phosphorylase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357662.1"
                     /db_xref="GI:15902112"
                     /db_xref="GeneID:932794"
     repeat_region   76338..76427
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_bb"
     gene            76547..76705
                     /locus_tag="spr0069"
                     /db_xref="GeneID:934052"
     CDS             76547..76705
                     /locus_tag="spr0069"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357663.1"
                     /db_xref="GI:15902113"
                     /db_xref="GeneID:934052"
     gene            76686..78065
                     /gene="trkH"
                     /locus_tag="spr0070"
                     /db_xref="GeneID:932801"
     CDS             76686..78065
                     /gene="trkH"
                     /locus_tag="spr0070"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk transporter membrane-spanning protein"
                     /protein_id="NP_357664.1"
                     /db_xref="GI:15902114"
                     /db_xref="GeneID:932801"
     gene            78058..78744
                     /gene="trkA"
                     /locus_tag="spr0071"
                     /db_xref="GeneID:932799"
     CDS             78058..78744
                     /gene="trkA"
                     /locus_tag="spr0071"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk transporter NAD+ binding protein"
                     /protein_id="NP_357665.1"
                     /db_xref="GI:15902115"
                     /db_xref="GeneID:932799"
     repeat_region   complement(78872..79021)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            79054..80070
                     /locus_tag="spr0072"
                     /pseudogene="unknown"
                     /db_xref="GeneID:932800"
     gene            80186..83671
                     /locus_tag="spr0075"
                     /db_xref="GeneID:932818"
     CDS             80186..83671
                     /locus_tag="spr0075"
                     /note="Similar to cell wall-associated serine proteinase"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor family protein"
                     /protein_id="NP_357669.1"
                     /db_xref="GI:15902119"
                     /db_xref="GeneID:932818"
     gene            83838..84536
                     /gene="rr08"
                     /locus_tag="spr0076"
                     /db_xref="GeneID:932813"
     CDS             83838..84536
                     /gene="rr08"
                     /locus_tag="spr0076"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_357670.1"
                     /db_xref="GI:15902120"
                     /db_xref="GeneID:932813"
     gene            84533..85585
                     /gene="hk08"
                     /locus_tag="spr0077"
                     /db_xref="GeneID:932804"
     CDS             84533..85585
                     /gene="hk08"
                     /locus_tag="spr0077"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="NP_357671.1"
                     /db_xref="GI:15902121"
                     /db_xref="GeneID:932804"
     gene            85780..86391
                     /gene="rpsD"
                     /locus_tag="spr0078"
                     /db_xref="GeneID:932816"
     CDS             85780..86391
                     /gene="rpsD"
                     /locus_tag="spr0078"
                     /note="primary rRNA binding protein; nucleates 30S
                     assembly; involved in translational accuracy with proteins
                     S5 and S12; interacts with protein S5; involved in
                     autogeneously regulating ribosomal proteins by binding to
                     pseudoknot structures in the polycistronic mRNA; interacts
                     with transcription complex and functions similar to
                     protein NusA in antitermination"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="NP_357672.1"
                     /db_xref="GI:15902122"
                     /db_xref="GeneID:932816"
     gene            86559..86735
                     /gene="transposase_A"
                     /locus_tag="spr0079"
                     /db_xref="GeneID:932823"
     CDS             86559..86735
                     /gene="transposase_A"
                     /locus_tag="spr0079"
                     /codon_start=1
                     /transl_table=11
                     /product="degenerative transposase"
                     /protein_id="NP_357673.1"
                     /db_xref="GI:15902123"
                     /db_xref="GeneID:932823"
     repeat_region   86731..86837
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            87044..87313
                     /locus_tag="spr0080"
                     /db_xref="GeneID:932834"
     CDS             87044..87313
                     /locus_tag="spr0080"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357674.1"
                     /db_xref="GI:15902124"
                     /db_xref="GeneID:932834"
     gene            87777..88736
                     /gene="ABC-MSP"
                     /locus_tag="spr0081"
                     /db_xref="GeneID:932828"
     CDS             87777..88736
                     /gene="ABC-MSP"
                     /locus_tag="spr0081"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_357675.1"
                     /db_xref="GI:15902125"
                     /db_xref="GeneID:932828"
     gene            88750..89673
                     /gene="ABC-MSP"
                     /locus_tag="spr0082"
                     /db_xref="GeneID:932824"
     CDS             88750..89673
                     /gene="ABC-MSP"
                     /locus_tag="spr0082"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_357676.1"
                     /db_xref="GI:15902126"
                     /db_xref="GeneID:932824"
     repeat_region   89725..89881
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            89862..91406
                     /gene="ABC-SBP"
                     /locus_tag="spr0083"
                     /db_xref="GeneID:932838"
     CDS             89862..91406
                     /gene="ABC-SBP"
                     /locus_tag="spr0083"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="NP_357677.1"
                     /db_xref="GI:15902127"
                     /db_xref="GeneID:932838"
     gene            91678..92664
                     /locus_tag="spr0084"
                     /db_xref="GeneID:932820"
     CDS             91678..92664
                     /locus_tag="spr0084"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357678.1"
                     /db_xref="GI:15902128"
                     /db_xref="GeneID:932820"
     gene            92633..93646
                     /locus_tag="spr0085"
                     /db_xref="GeneID:932845"
     CDS             92633..93646
                     /locus_tag="spr0085"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357679.1"
                     /db_xref="GI:15902129"
                     /db_xref="GeneID:932845"
     gene            complement(93718..94782)
                     /locus_tag="spr0086"
                     /db_xref="GeneID:932843"
     CDS             complement(93718..94782)
                     /locus_tag="spr0086"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357680.1"
                     /db_xref="GI:15902130"
                     /db_xref="GeneID:932843"
     gene            complement(94845..95807)
                     /locus_tag="spr0087"
                     /db_xref="GeneID:932839"
     CDS             complement(94845..95807)
                     /locus_tag="spr0087"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357681.1"
                     /db_xref="GI:15902131"
                     /db_xref="GeneID:932839"
     gene            complement(95749..96342)
                     /locus_tag="spr0088"
                     /db_xref="GeneID:932844"
     CDS             complement(95749..96342)
                     /locus_tag="spr0088"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357682.1"
                     /db_xref="GI:15902132"
                     /db_xref="GeneID:932844"
     gene            complement(96329..96655)
                     /locus_tag="spr0089"
                     /db_xref="GeneID:932854"
     CDS             complement(96329..96655)
                     /locus_tag="spr0089"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357683.1"
                     /db_xref="GI:15902133"
                     /db_xref="GeneID:932854"
     gene            complement(96794..97960)
                     /locus_tag="spr0090"
                     /db_xref="GeneID:932858"
     CDS             complement(96794..97960)
                     /locus_tag="spr0090"
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="NP_357684.1"
                     /db_xref="GI:15902134"
                     /db_xref="GeneID:932858"
     gene            98018..99175
                     /locus_tag="spr0091"
                     /db_xref="GeneID:932836"
     CDS             98018..99175
                     /locus_tag="spr0091"
                     /note="sugar transferase related protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357685.1"
                     /db_xref="GI:15902135"
                     /db_xref="GeneID:932836"
     gene            99217..101067
                     /gene="capD"
                     /locus_tag="spr0092"
                     /db_xref="GeneID:932856"
     CDS             99217..101067
                     /gene="capD"
                     /locus_tag="spr0092"
                     /codon_start=1
                     /transl_table=11
                     /product="capsule polysaccharide biosynthesis protein
                     CapD"
                     /protein_id="NP_357686.1"
                     /db_xref="GI:15902136"
                     /db_xref="GeneID:932856"
     repeat_region   101134..101420
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbbbc"
     gene            complement(101463..102095)
                     /gene="gph"
                     /locus_tag="spr0093"
                     /db_xref="GeneID:932857"
     CDS             complement(101463..102095)
                     /gene="gph"
                     /locus_tag="spr0093"
                     /EC_number="3.1.3.18"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="NP_357687.1"
                     /db_xref="GI:15902137"
                     /db_xref="GeneID:932857"
     gene            complement(102117..102989)
                     /gene="sdaA"
                     /locus_tag="spr0094"
                     /db_xref="GeneID:932859"
     CDS             complement(102117..102989)
                     /gene="sdaA"
                     /locus_tag="spr0094"
                     /EC_number="4.3.1.17"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine dehydratase subunit alpha"
                     /protein_id="NP_357688.1"
                     /db_xref="GI:15902138"
                     /db_xref="GeneID:932859"
     gene            complement(102998..103669)
                     /gene="sdaB"
                     /locus_tag="spr0095"
                     /db_xref="GeneID:932851"
     CDS             complement(102998..103669)
                     /gene="sdaB"
                     /locus_tag="spr0095"
                     /EC_number="4.3.1.17"
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine dehydratase subunit beta"
                     /protein_id="NP_357689.1"
                     /db_xref="GI:15902139"
                     /db_xref="GeneID:932851"
     gene            103911..104414
                     /locus_tag="spr0096"
                     /db_xref="GeneID:932867"
     CDS             103911..104414
                     /locus_tag="spr0096"
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="NP_357690.1"
                     /db_xref="GI:15902140"
                     /db_xref="GeneID:932867"
     gene            105242..105490
                     /locus_tag="spr0098"
                     /db_xref="GeneID:932864"
     CDS             105242..105490
                     /locus_tag="spr0098"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="NP_357692.1"
                     /db_xref="GI:15902142"
                     /db_xref="GeneID:932864"
     gene            105545..107653
                     /gene="ABC-MSP"
                     /locus_tag="spr0099"
                     /db_xref="GeneID:932866"
     CDS             105545..107653
                     /gene="ABC-MSP"
                     /locus_tag="spr0099"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_357693.1"
                     /db_xref="GI:15902143"
                     /db_xref="GeneID:932866"
     gene            107650..108291
                     /gene="ABC-NBD"
                     /locus_tag="spr0100"
                     /db_xref="GeneID:932876"
     CDS             107650..108291
                     /gene="ABC-NBD"
                     /locus_tag="spr0100"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_357694.1"
                     /db_xref="GI:15902144"
                     /db_xref="GeneID:932876"
     gene            108506..109303
                     /gene="ABC-SBP"
                     /locus_tag="spr0101"
                     /db_xref="GeneID:932861"
     CDS             108506..109303
                     /gene="ABC-SBP"
                     /locus_tag="spr0101"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_357695.1"
                     /db_xref="GI:15902145"
                     /db_xref="GeneID:932861"
     gene            109269..110516
                     /gene="argG"
                     /locus_tag="spr0102"
                     /db_xref="GeneID:932865"
     CDS             109269..110516
                     /gene="argG"
                     /locus_tag="spr0102"
                     /EC_number="6.3.4.5"
                     /note="catalyzes the formation of
                     2-N(omega)-(L-arginino)succinate from L-citrulline and
                     L-aspartate in arginine biosynthesis, AMP-forming"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="NP_357696.1"
                     /db_xref="GI:15902146"
                     /db_xref="GeneID:932865"
     gene            110545..111936
                     /gene="argH"
                     /locus_tag="spr0103"
                     /db_xref="GeneID:932888"
     CDS             110545..111936
                     /gene="argH"
                     /locus_tag="spr0103"
                     /EC_number="4.3.2.1"
                     /note="catalyzes the formation of arginine from
                     (N-L-arginino)succinate"
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="NP_357697.1"
                     /db_xref="GI:15902147"
                     /db_xref="GeneID:932888"
     gene            complement(112225..113124)
                     /locus_tag="spr0104"
                     /db_xref="GeneID:932874"
     CDS             complement(112225..113124)
                     /locus_tag="spr0104"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357698.1"
                     /db_xref="GI:15902148"
                     /db_xref="GeneID:932874"
     gene            113839..115773
                     /locus_tag="spr0106"
                     /db_xref="GeneID:932887"
     CDS             113839..115773
                     /locus_tag="spr0106"
                     /note="Similar to competence factor transporting
                     ATP-binding/permease ComA"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/ATP-binding protein"
                     /protein_id="NP_357700.1"
                     /db_xref="GI:15902150"
                     /db_xref="GeneID:932887"
     gene            115766..116233
                     /locus_tag="spr0107"
                     /db_xref="GeneID:932869"
     CDS             115766..116233
                     /locus_tag="spr0107"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357701.1"
                     /db_xref="GI:15902151"
                     /db_xref="GeneID:932869"
     gene            116230..117582
                     /locus_tag="spr0108"
                     /db_xref="GeneID:932889"
     CDS             116230..117582
                     /locus_tag="spr0108"
                     /note="Similar to ComB protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357702.1"
                     /db_xref="GI:15902152"
                     /db_xref="GeneID:932889"
     gene            117728..118108
                     /locus_tag="spr0109"
                     /db_xref="GeneID:932896"
     CDS             117728..118108
                     /locus_tag="spr0109"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357703.1"
                     /db_xref="GI:15902153"
                     /db_xref="GeneID:932896"
     gene            complement(118611..118931)
                     /locus_tag="spr0110"
                     /db_xref="GeneID:932885"
     CDS             complement(118611..118931)
                     /locus_tag="spr0110"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357704.1"
                     /db_xref="GI:15902154"
                     /db_xref="GeneID:932885"
     gene            119688..120059
                     /locus_tag="spr0111"
                     /db_xref="GeneID:932883"
     CDS             119688..120059
                     /locus_tag="spr0111"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357705.1"
                     /db_xref="GI:15902155"
                     /db_xref="GeneID:932883"
     gene            120067..120279
                     /locus_tag="spr0112"
                     /db_xref="GeneID:932895"
     CDS             120067..120279
                     /locus_tag="spr0112"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357706.1"
                     /db_xref="GI:15902156"
                     /db_xref="GeneID:932895"
     gene            121084..122142
                     /locus_tag="spr0113"
                     /db_xref="GeneID:932879"
     CDS             121084..122142
                     /locus_tag="spr0113"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357707.1"
                     /db_xref="GI:15902157"
                     /db_xref="GeneID:932879"
     gene            122441..123433
                     /locus_tag="spr0114"
                     /db_xref="GeneID:932880"
     CDS             122441..123433
                     /locus_tag="spr0114"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357708.1"
                     /db_xref="GI:15902158"
                     /db_xref="GeneID:932880"
     gene            123810..124184
                     /locus_tag="spr0115"
                     /db_xref="GeneID:932891"
     CDS             123810..124184
                     /locus_tag="spr0115"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357709.1"
                     /db_xref="GI:15902159"
                     /db_xref="GeneID:932891"
     gene            124191..124373
                     /locus_tag="spr0116"
                     /db_xref="GeneID:932892"
     CDS             124191..124373
                     /locus_tag="spr0116"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357710.1"
                     /db_xref="GI:15902160"
                     /db_xref="GeneID:932892"
     gene            124392..125294
                     /locus_tag="spr0117"
                     /db_xref="GeneID:932893"
     CDS             124392..125294
                     /locus_tag="spr0117"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357711.1"
                     /db_xref="GI:15902161"
                     /db_xref="GeneID:932893"
     gene            125317..125703
                     /locus_tag="spr0118"
                     /db_xref="GeneID:932899"
     CDS             125317..125703
                     /locus_tag="spr0118"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357712.1"
                     /db_xref="GI:15902162"
                     /db_xref="GeneID:932899"
     gene            125670..126428
                     /locus_tag="spr0119"
                     /db_xref="GeneID:932890"
     CDS             125670..126428
                     /locus_tag="spr0119"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357713.1"
                     /db_xref="GI:15902163"
                     /db_xref="GeneID:932890"
     gene            126907..127104
                     /locus_tag="spr0119a"
                     /db_xref="GeneID:17374504"
     CDS             126907..127104
                     /locus_tag="spr0119a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719799.1"
                     /db_xref="GI:555247345"
                     /db_xref="GeneID:17374504"
     repeat_region   127282..127350
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            127503..127802
                     /locus_tag="spr0120"
                     /db_xref="GeneID:932897"
     CDS             127503..127802
                     /locus_tag="spr0120"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357714.1"
                     /db_xref="GI:15902164"
                     /db_xref="GeneID:932897"
     gene            128356..130215
                     /gene="pspA"
                     /locus_tag="spr0121"
                     /db_xref="GeneID:932894"
     CDS             128356..130215
                     /gene="pspA"
                     /locus_tag="spr0121"
                     /codon_start=1
                     /transl_table=11
                     /product="surface protein pspA"
                     /protein_id="NP_357715.1"
                     /db_xref="GI:15902165"
                     /db_xref="GeneID:932894"
     gene            130562..131737
                     /gene="mnmA"
                     /locus_tag="spr0122"
                     /db_xref="GeneID:932900"
     CDS             130562..131737
                     /gene="mnmA"
                     /locus_tag="spr0122"
                     /EC_number="2.1.1.61"
                     /note="catalyzes a sulfuration reaction to synthesize
                     2-thiouridine at the U34 position of tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-specific 2-thiouridylase MnmA"
                     /protein_id="NP_357716.1"
                     /db_xref="GI:15902166"
                     /db_xref="GeneID:932900"
     gene            131851..132333
                     /locus_tag="spr0123"
                     /db_xref="GeneID:932906"
     CDS             131851..132333
                     /locus_tag="spr0123"
                     /note="Similar to MutT protein"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="NP_357717.1"
                     /db_xref="GI:15902167"
                     /db_xref="GeneID:932906"
     gene            132343..134256
                     /gene="gidA"
                     /locus_tag="spr0124"
                     /db_xref="GeneID:932898"
     CDS             132343..134256
                     /gene="gidA"
                     /locus_tag="spr0124"
                     /note="GidA; glucose-inhibited cell division protein A;
                     involved in the 5-carboxymethylaminomethyl modification
                     (mnm(5)s(2)U) of the wobble uridine base in some tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-carboxymethylaminomethyl
                     modification protein GidA"
                     /protein_id="NP_357718.1"
                     /db_xref="GI:15902168"
                     /db_xref="GeneID:932898"
     repeat_region   complement(134454..134633)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(134636..136468)
                     /locus_tag="spr0125"
                     /db_xref="GeneID:934629"
     CDS             complement(134636..136468)
                     /locus_tag="spr0125"
                     /note="Predicted hydrolase of the metallo-beta-lactamase
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357719.1"
                     /db_xref="GI:15902169"
                     /db_xref="GeneID:934629"
     gene            complement(136317..136550)
                     /locus_tag="spr0126"
                     /db_xref="GeneID:932901"
     CDS             complement(136317..136550)
                     /locus_tag="spr0126"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357720.1"
                     /db_xref="GI:15902170"
                     /db_xref="GeneID:932901"
     gene            complement(137368..137520)
                     /gene="orf51"
                     /locus_tag="spr0127"
                     /db_xref="GeneID:934632"
     CDS             complement(137368..137520)
                     /gene="orf51"
                     /locus_tag="spr0127"
                     /note="Induced during competence"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357721.1"
                     /db_xref="GI:15902171"
                     /db_xref="GeneID:934632"
     gene            complement(137522..137707)
                     /locus_tag="spr0128"
                     /db_xref="GeneID:934875"
     CDS             complement(137522..137707)
                     /locus_tag="spr0128"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357722.1"
                     /db_xref="GI:15902172"
                     /db_xref="GeneID:934875"
     gene            137885..138568
                     /locus_tag="spr0129"
                     /db_xref="GeneID:932905"
     CDS             137885..138568
                     /locus_tag="spr0129"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357723.1"
                     /db_xref="GI:15902173"
                     /db_xref="GeneID:932905"
     gene            138565..139002
                     /gene="rimI"
                     /locus_tag="spr0130"
                     /db_xref="GeneID:932904"
     CDS             138565..139002
                     /gene="rimI"
                     /locus_tag="spr0130"
                     /EC_number="2.3.1.128"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein alanine acetyltransferase"
                     /protein_id="NP_357724.1"
                     /db_xref="GI:15902174"
                     /db_xref="GeneID:932904"
     gene            138992..140002
                     /gene="gcp"
                     /locus_tag="spr0131"
                     /db_xref="GeneID:934879"
     CDS             138992..140002
                     /gene="gcp"
                     /locus_tag="spr0131"
                     /EC_number="3.4.24.57"
                     /note="in most organisms, only the N-terminal domain is
                     present in a single polypeptide; in some archaea this
                     domain is fused to a kinase domain; this gene is essential
                     for growth in Escherichia coli and Bacillus subtilis; the
                     secreted glycoprotease from Pasteurella haemolytica showed
                     specificity for O-sialoglycosylated proteins; the
                     Pyrococcus structure shows DNA-binding properties,
                     iron-binding, ATP-binding, and AP endonuclease activity"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding/iron metalloprotein/AP endonuclease"
                     /protein_id="NP_357725.1"
                     /db_xref="GI:15902175"
                     /db_xref="GeneID:934879"
     gene            complement(140042..140853)
                     /gene="IS1167-truncation"
                     /locus_tag="spr0132"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934630"
     gene            142595..143809
                     /gene="epsG"
                     /locus_tag="spr0135"
                     /db_xref="GeneID:934883"
     CDS             142595..143809
                     /gene="epsG"
                     /locus_tag="spr0135"
                     /codon_start=1
                     /transl_table=11
                     /product="exopolysaccharide (EPS) synthesis
                     glycosyltransferase"
                     /protein_id="NP_357729.1"
                     /db_xref="GI:15902179"
                     /db_xref="GeneID:934883"
     gene            143802..144755
                     /gene="glycosyltransferase"
                     /locus_tag="spr0136"
                     /db_xref="GeneID:934876"
     CDS             143802..144755
                     /gene="glycosyltransferase"
                     /locus_tag="spr0136"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="NP_357730.1"
                     /db_xref="GI:15902180"
                     /db_xref="GeneID:934876"
     gene            144765..146381
                     /gene="ABC-NP"
                     /locus_tag="spr0137"
                     /db_xref="GeneID:934878"
     CDS             144765..146381
                     /gene="ABC-NP"
                     /locus_tag="spr0137"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_357731.1"
                     /db_xref="GI:15902181"
                     /db_xref="GeneID:934878"
     gene            147164..147919
                     /locus_tag="spr0138"
                     /db_xref="GeneID:934887"
     CDS             147164..147919
                     /locus_tag="spr0138"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357732.1"
                     /db_xref="GI:15902182"
                     /db_xref="GeneID:934887"
     gene            147932..149104
                     /gene="ugd"
                     /locus_tag="spr0139"
                     /db_xref="GeneID:934890"
     CDS             147932..149104
                     /gene="ugd"
                     /locus_tag="spr0139"
                     /EC_number="1.1.1.22"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose dehydrogenase"
                     /protein_id="NP_357733.1"
                     /db_xref="GI:15902183"
                     /db_xref="GeneID:934890"
     gene            149499..150362
                     /gene="mutR"
                     /locus_tag="spr0140"
                     /db_xref="GeneID:934880"
     CDS             149499..150362
                     /gene="mutR"
                     /locus_tag="spr0140"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_357734.1"
                     /db_xref="GI:15902184"
                     /db_xref="GeneID:934880"
     gene            150653..150886
                     /locus_tag="spr0141"
                     /db_xref="GeneID:934894"
     CDS             150653..150886
                     /locus_tag="spr0141"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357735.1"
                     /db_xref="GI:15902185"
                     /db_xref="GeneID:934894"
     gene            150908..151585
                     /locus_tag="spr0142"
                     /db_xref="GeneID:934881"
     CDS             150908..151585
                     /locus_tag="spr0142"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357736.1"
                     /db_xref="GI:15902186"
                     /db_xref="GeneID:934881"
     gene            151597..152262
                     /locus_tag="spr0143"
                     /db_xref="GeneID:934885"
     CDS             151597..152262
                     /locus_tag="spr0143"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357737.1"
                     /db_xref="GI:15902187"
                     /db_xref="GeneID:934885"
     gene            152331..153560
                     /locus_tag="spr0144"
                     /db_xref="GeneID:934888"
     CDS             152331..153560
                     /locus_tag="spr0144"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357738.1"
                     /db_xref="GI:15902188"
                     /db_xref="GeneID:934888"
     repeat_region   153654..153760
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     repeat_region   153858..153891
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            154470..155300
                     /gene="ABC-SBP"
                     /locus_tag="spr0146"
                     /db_xref="GeneID:934902"
     CDS             154470..155300
                     /gene="ABC-SBP"
                     /locus_tag="spr0146"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_357740.1"
                     /db_xref="GI:15902190"
                     /db_xref="GeneID:934902"
     gene            155454..156308
                     /gene="ABC-SBP"
                     /locus_tag="spr0147"
                     /db_xref="GeneID:934877"
     CDS             155454..156308
                     /gene="ABC-SBP"
                     /locus_tag="spr0147"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="NP_357741.1"
                     /db_xref="GI:15902191"
                     /db_xref="GeneID:934877"
     gene            156408..157781
                     /gene="dapE"
                     /locus_tag="spr0148"
                     /db_xref="GeneID:934884"
     CDS             156408..157781
                     /gene="dapE"
                     /locus_tag="spr0148"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357742.1"
                     /db_xref="GI:15902192"
                     /db_xref="GeneID:934884"
     gene            157774..158835
                     /gene="ABC-NBD"
                     /locus_tag="spr0149"
                     /db_xref="GeneID:934901"
     CDS             157774..158835
                     /gene="ABC-NBD"
                     /locus_tag="spr0149"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_357743.1"
                     /db_xref="GI:15902193"
                     /db_xref="GeneID:934901"
     gene            158837..159529
                     /gene="ABC-MSD"
                     /locus_tag="spr0150"
                     /db_xref="GeneID:934898"
     CDS             158837..159529
                     /gene="ABC-MSD"
                     /locus_tag="spr0150"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_357744.1"
                     /db_xref="GI:15902194"
                     /db_xref="GeneID:934898"
     gene            complement(159559..160128)
                     /locus_tag="spr0151"
                     /db_xref="GeneID:934904"
     CDS             complement(159559..160128)
                     /locus_tag="spr0151"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357745.1"
                     /db_xref="GI:15902195"
                     /db_xref="GeneID:934904"
     gene            160263..160877
                     /locus_tag="spr0152"
                     /db_xref="GeneID:934895"
     CDS             160263..160877
                     /locus_tag="spr0152"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357746.1"
                     /db_xref="GI:15902196"
                     /db_xref="GeneID:934895"
     gene            160855..162525
                     /gene="hk07"
                     /locus_tag="spr0153"
                     /db_xref="GeneID:934900"
     CDS             160855..162525
                     /gene="hk07"
                     /locus_tag="spr0153"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="NP_357747.2"
                     /db_xref="GI:555247343"
                     /db_xref="GeneID:934900"
     gene            162537..163823
                     /gene="rr07"
                     /locus_tag="spr0154"
                     /db_xref="GeneID:934903"
     CDS             162537..163823
                     /gene="rr07"
                     /locus_tag="spr0154"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_357748.1"
                     /db_xref="GI:15902198"
                     /db_xref="GeneID:934903"
     gene            163827..164408
                     /locus_tag="spr0155"
                     /db_xref="GeneID:934897"
     CDS             163827..164408
                     /locus_tag="spr0155"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357749.1"
                     /db_xref="GI:15902199"
                     /db_xref="GeneID:934897"
     gene            164486..164956
                     /locus_tag="spr0156"
                     /db_xref="GeneID:934899"
     CDS             164486..164956
                     /locus_tag="spr0156"
                     /note="has a stimulatory effect on the ribonucleotide
                     reductase activity of NrdH with NrdEF"
                     /codon_start=1
                     /transl_table=11
                     /product="flavoprotein NrdI"
                     /protein_id="NP_357750.2"
                     /db_xref="GI:651852198"
                     /db_xref="GeneID:934899"
     repeat_region   complement(164956..165068)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(165249..166511)
                     /locus_tag="spr0157"
                     /db_xref="GeneID:934021"
     CDS             complement(165249..166511)
                     /locus_tag="spr0157"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357751.1"
                     /db_xref="GI:15902201"
                     /db_xref="GeneID:934021"
     repeat_region   166648..166754
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(166821..167279)
                     /locus_tag="spr0158"
                     /db_xref="GeneID:932902"
     CDS             complement(166821..167279)
                     /locus_tag="spr0158"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357752.1"
                     /db_xref="GI:15902202"
                     /db_xref="GeneID:932902"
     gene            complement(167276..167797)
                     /locus_tag="spr0159"
                     /db_xref="GeneID:934023"
     CDS             complement(167276..167797)
                     /locus_tag="spr0159"
                     /note="Similar to autolysin response regulator in Bacillus
                     subtilis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357753.1"
                     /db_xref="GI:15902203"
                     /db_xref="GeneID:934023"
     repeat_region   167773..167925
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            168072..170021
                     /gene="mutL"
                     /locus_tag="spr0160"
                     /db_xref="GeneID:934896"
     CDS             168072..170021
                     /gene="mutL"
                     /locus_tag="spr0160"
                     /note="This protein is involved in the repair of
                     mismatches in DNA. It is required for dam-dependent
                     methyl-directed DNA mismatch repair. Promotes the
                     formation of a stable complex between two or more
                     DNA-binding proteins in an ATP-dependent manner without
                     itself being part of a final effector complex"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein"
                     /protein_id="NP_357754.1"
                     /db_xref="GI:15902204"
                     /db_xref="GeneID:934896"
     repeat_region   170144..170286
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(170346..170813)
                     /gene="ribH"
                     /locus_tag="spr0161"
                     /db_xref="GeneID:933803"
     CDS             complement(170346..170813)
                     /gene="ribH"
                     /locus_tag="spr0161"
                     /EC_number="2.5.1.9"
                     /note="RibE; 6,7-diimethyl-8-ribityllumazine synthase;
                     DMRL synthase; lumazine synthase; beta subunit of
                     riboflavin synthase; condenses
                     5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione
                     with L-3,4-dihydrohy-2-butanone-4-phosphate to generate
                     6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then
                     uses 2 molecules of DMRL to produce riboflavin (vitamin
                     B12); involved in the last steps of riboflavin
                     biosynthesis; forms a 60mer (icosahedral shell) in both
                     Bacillus subtilis and Escherichia coli; in Bacillus
                     subtilis this 60mer is associated with the riboflavin
                     synthase subunit (alpha) while in Escherichia coli it is
                     not"
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="NP_357755.1"
                     /db_xref="GI:15902205"
                     /db_xref="GeneID:933803"
     gene            complement(170814..172019)
                     /gene="ribA"
                     /locus_tag="spr0162"
                     /db_xref="GeneID:934025"
     CDS             complement(170814..172019)
                     /gene="ribA"
                     /locus_tag="spr0162"
                     /EC_number="3.5.4.25"
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone 4-phosphate synthase"
                     /protein_id="NP_357756.1"
                     /db_xref="GI:15902206"
                     /db_xref="GeneID:934025"
     gene            complement(172039..172674)
                     /gene="ribC"
                     /locus_tag="spr0163"
                     /db_xref="GeneID:933132"
     CDS             complement(172039..172674)
                     /gene="ribC"
                     /locus_tag="spr0163"
                     /EC_number="2.5.1.9"
                     /note="catalyzes the formation of riboflavin from
                     6,7-dimethyl-8-(1-D-ribityl)lumazine"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase subunit alpha"
                     /protein_id="NP_357757.1"
                     /db_xref="GI:15902207"
                     /db_xref="GeneID:933132"
     gene            complement(172659..173759)
                     /gene="ribD"
                     /locus_tag="spr0164"
                     /db_xref="GeneID:933106"
     CDS             complement(172659..173759)
                     /gene="ribD"
                     /locus_tag="spr0164"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibD"
                     /protein_id="NP_357758.1"
                     /db_xref="GI:15902208"
                     /db_xref="GeneID:933106"
     gene            174163..174756
                     /gene="ruvA"
                     /locus_tag="spr0165"
                     /db_xref="GeneID:933035"
     CDS             174163..174756
                     /gene="ruvA"
                     /locus_tag="spr0165"
                     /note="plays an essential role in ATP-dependent branch
                     migration of the Holliday junction"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction DNA helicase RuvA"
                     /protein_id="NP_357759.1"
                     /db_xref="GI:15902209"
                     /db_xref="GeneID:933035"
     gene            174766..175329
                     /gene="tag"
                     /locus_tag="spr0166"
                     /db_xref="GeneID:933894"
     CDS             174766..175329
                     /gene="tag"
                     /locus_tag="spr0166"
                     /EC_number="3.2.2.20"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="NP_357760.1"
                     /db_xref="GI:15902210"
                     /db_xref="GeneID:933894"
     gene            175326..176003
                     /locus_tag="spr0167"
                     /db_xref="GeneID:932875"
     CDS             175326..176003
                     /locus_tag="spr0167"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357761.1"
                     /db_xref="GI:15902211"
                     /db_xref="GeneID:932875"
     repeat_region   complement(175991..176089)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(176158..177189)
                     /locus_tag="spr0168"
                     /db_xref="GeneID:933807"
     CDS             complement(176158..177189)
                     /locus_tag="spr0168"
                     /note="MccF-like proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="MccC family protein"
                     /protein_id="NP_357762.1"
                     /db_xref="GI:15902212"
                     /db_xref="GeneID:933807"
     repeat_region   complement(177273..177389)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(177444..178148)
                     /locus_tag="spr0169"
                     /db_xref="GeneID:933844"
     CDS             complement(177444..178148)
                     /locus_tag="spr0169"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357763.1"
                     /db_xref="GI:15902213"
                     /db_xref="GeneID:933844"
     gene            complement(178139..179083)
                     /gene="corA"
                     /locus_tag="spr0170"
                     /db_xref="GeneID:933183"
     CDS             complement(178139..179083)
                     /gene="corA"
                     /locus_tag="spr0170"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="NP_357764.1"
                     /db_xref="GI:15902214"
                     /db_xref="GeneID:933183"
     gene            179215..182046
                     /gene="uvrA"
                     /locus_tag="spr0171"
                     /db_xref="GeneID:933838"
     CDS             179215..182046
                     /gene="uvrA"
                     /locus_tag="spr0171"
                     /note="The UvrABC repair system catalyzes the recognition
                     and processing of DNA lesions. UvrA is an ATPase and a
                     DNA-binding protein. A damage recognition complex composed
                     of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities.
                     When the presence of a lesion has been verified by uvrB,
                     the uvrA molecules dissociate"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit A"
                     /protein_id="NP_357765.1"
                     /db_xref="GI:15902215"
                     /db_xref="GeneID:933838"
     gene            182039..183100
                     /gene="pepP"
                     /locus_tag="spr0172"
                     /db_xref="GeneID:933987"
     CDS             182039..183100
                     /gene="pepP"
                     /locus_tag="spr0172"
                     /EC_number="3.4.11.9"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M24 family protein"
                     /protein_id="NP_357766.1"
                     /db_xref="GI:15902216"
                     /db_xref="GeneID:933987"
     gene            183232..183630
                     /gene="spxA"
                     /locus_tag="spr0173"
                     /gene_synonym="yjbD"
                     /db_xref="GeneID:933168"
     CDS             183232..183630
                     /gene="spxA"
                     /locus_tag="spr0173"
                     /gene_synonym="yjbD"
                     /note="the anti-alpha factor Spx interacts with RNA
                     polymerase alpha subunit C-terminal domain in a region
                     that interacts with the sigma 70 subunit and may interfere
                     with activation of promoters; in Bacillus subtilis this
                     protein is a substrate for ClpXP protease; blocks
                     transcription of the competence regulatory gene encoded by
                     the srf operon; regulates a number of genes involved in
                     thiol homeostasis including trxA and trxB; monomeric
                     member of ArsC family of proteins; does not bind DNA;
                     contains a disulfide bond between C10 and C13 which may
                     sense disulfide stress"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="NP_357767.1"
                     /db_xref="GI:15902217"
                     /db_xref="GeneID:933168"
     gene            183696..184265
                     /locus_tag="spr0174"
                     /db_xref="GeneID:933777"
     CDS             183696..184265
                     /locus_tag="spr0174"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357768.1"
                     /db_xref="GI:15902218"
                     /db_xref="GeneID:933777"
     gene            184352..184618
                     /locus_tag="spr0175"
                     /db_xref="GeneID:933164"
     CDS             184352..184618
                     /locus_tag="spr0175"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357769.1"
                     /db_xref="GI:15902219"
                     /db_xref="GeneID:933164"
     gene            184622..185041
                     /locus_tag="spr0176"
                     /db_xref="GeneID:933212"
     CDS             184622..185041
                     /locus_tag="spr0176"
                     /note="similar to RuvC resolvase with substantial
                     differences; NMR structural information suggests this
                     protein is monomeric; unknown cellular function"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase-like protein"
                     /protein_id="NP_357770.1"
                     /db_xref="GI:15902220"
                     /db_xref="GeneID:933212"
     gene            185057..185362
                     /locus_tag="spr0177"
                     /db_xref="GeneID:933178"
     CDS             185057..185362
                     /locus_tag="spr0177"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357771.1"
                     /db_xref="GI:15902221"
                     /db_xref="GeneID:933178"
     gene            185813..187069
                     /gene="folC"
                     /locus_tag="spr0178"
                     /db_xref="GeneID:933972"
     CDS             185813..187069
                     /gene="folC"
                     /locus_tag="spr0178"
                     /EC_number="6.3.2.12"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate:folylpolyglutamate synthetase"
                     /protein_id="NP_357772.1"
                     /db_xref="GI:15902222"
                     /db_xref="GeneID:933972"
     gene            187066..187584
                     /locus_tag="spr0179"
                     /db_xref="GeneID:932873"
     CDS             187066..187584
                     /locus_tag="spr0179"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357773.1"
                     /db_xref="GI:15902223"
                     /db_xref="GeneID:932873"
     gene            187730..189262
                     /gene="cls"
                     /locus_tag="spr0180"
                     /db_xref="GeneID:933187"
     CDS             187730..189262
                     /gene="cls"
                     /locus_tag="spr0180"
                     /EC_number="2.7.8.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthetase"
                     /protein_id="NP_357774.1"
                     /db_xref="GI:15902224"
                     /db_xref="GeneID:933187"
     gene            189340..189483
                     /gene="orf47"
                     /locus_tag="spr0181"
                     /db_xref="GeneID:933180"
     CDS             189340..189483
                     /gene="orf47"
                     /locus_tag="spr0181"
                     /note="Induced during competence"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357775.1"
                     /db_xref="GI:15902225"
                     /db_xref="GeneID:933180"
     gene            189502..191058
                     /locus_tag="spr0182"
                     /db_xref="GeneID:932988"
     CDS             189502..191058
                     /locus_tag="spr0182"
                     /note="Competence-induced protein Ccs4"
                     /codon_start=1
                     /transl_table=11
                     /product="competence-induced protein Ccs4"
                     /protein_id="NP_357776.1"
                     /db_xref="GI:15902226"
                     /db_xref="GeneID:932988"
     gene            191172..193385
                     /gene="nrdD"
                     /locus_tag="spr0183"
                     /db_xref="GeneID:932922"
     CDS             191172..193385
                     /gene="nrdD"
                     /locus_tag="spr0183"
                     /EC_number="1.17.4.2"
                     /note="Catalyzes the reduction of nucleoside
                     5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside triphosphate reductase"
                     /protein_id="NP_357777.1"
                     /db_xref="GI:15902227"
                     /db_xref="GeneID:932922"
     gene            193581..194087
                     /locus_tag="spr0184"
                     /db_xref="GeneID:932982"
     CDS             193581..194087
                     /locus_tag="spr0184"
                     /note="Similar to histone acetyltransferase HPA2 and
                     related acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357778.1"
                     /db_xref="GI:15902228"
                     /db_xref="GeneID:932982"
     gene            194080..194670
                     /gene="nrdG"
                     /locus_tag="spr0185"
                     /db_xref="GeneID:932981"
     CDS             194080..194670
                     /gene="nrdG"
                     /locus_tag="spr0185"
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="NP_357779.1"
                     /db_xref="GI:15902229"
                     /db_xref="GeneID:932981"
     gene            194667..195284
                     /locus_tag="spr0186"
                     /db_xref="GeneID:933102"
     CDS             194667..195284
                     /locus_tag="spr0186"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357780.1"
                     /db_xref="GI:15902230"
                     /db_xref="GeneID:933102"
     gene            195551..195859
                     /gene="rpsJ"
                     /locus_tag="spr0187"
                     /gene_synonym="nusE"
                     /db_xref="GeneID:932811"
     CDS             195551..195859
                     /gene="rpsJ"
                     /locus_tag="spr0187"
                     /gene_synonym="nusE"
                     /note="NusE; involved in assembly of the 30S subunit; in
                     the ribosome, this protein is involved in the binding of
                     tRNA; in Escherichia coli this protein was also found to
                     be involved in transcription antitermination; NusB/S10
                     heterodimers bind boxA sequences in the leader RNA of rrn
                     operons which is required for antitermination; binding of
                     NusB/S10 to boxA nucleates assembly of the antitermination
                     complex"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="NP_357781.1"
                     /db_xref="GI:15902231"
                     /db_xref="GeneID:932811"
     gene            196076..196702
                     /gene="rplC"
                     /locus_tag="spr0188"
                     /db_xref="GeneID:932979"
     CDS             196076..196702
                     /gene="rplC"
                     /locus_tag="spr0188"
                     /note="binds directly near the 3' end of the 23S rRNA,
                     where it nucleates assembly of the 50S subunit; essential
                     for peptidyltransferase activity; mutations in this gene
                     confer resistance to tiamulin"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="NP_357782.1"
                     /db_xref="GI:15902232"
                     /db_xref="GeneID:932979"
     gene            196727..197350
                     /gene="rplD"
                     /locus_tag="spr0189"
                     /db_xref="GeneID:933169"
     CDS             196727..197350
                     /gene="rplD"
                     /locus_tag="spr0189"
                     /note="L4 is important during the early stages of 50S
                     assembly; it initially binds near the 5' end of the 23S
                     rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="NP_357783.1"
                     /db_xref="GI:15902233"
                     /db_xref="GeneID:933169"
     gene            197350..197646
                     /gene="rplW"
                     /locus_tag="spr0190"
                     /db_xref="GeneID:932965"
     CDS             197350..197646
                     /gene="rplW"
                     /locus_tag="spr0190"
                     /note="binds third domain of 23S rRNA and protein L29;
                     part of exit tunnel"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="NP_357784.1"
                     /db_xref="GI:15902234"
                     /db_xref="GeneID:932965"
     gene            197664..198497
                     /gene="rplB"
                     /locus_tag="spr0191"
                     /db_xref="GeneID:933760"
     CDS             197664..198497
                     /gene="rplB"
                     /locus_tag="spr0191"
                     /note="one of the primary rRNA-binding proteins; required
                     for association of the 30S and 50S subunits to form the
                     70S ribosome, for tRNA binding and peptide bond formation"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="NP_357785.1"
                     /db_xref="GI:15902235"
                     /db_xref="GeneID:933760"
     gene            198601..198882
                     /gene="rpsS"
                     /locus_tag="spr0192"
                     /db_xref="GeneID:932870"
     CDS             198601..198882
                     /gene="rpsS"
                     /locus_tag="spr0192"
                     /note="protein S19 forms a complex with S13 that binds
                     strongly to the 16S ribosomal RNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="NP_357786.1"
                     /db_xref="GI:15902236"
                     /db_xref="GeneID:932870"
     gene            198894..199238
                     /gene="rplV"
                     /locus_tag="spr0194"
                     /db_xref="GeneID:932936"
     CDS             198894..199238
                     /gene="rplV"
                     /locus_tag="spr0194"
                     /note="binds specifically to 23S rRNA during the early
                     stages of 50S assembly; makes contact with all 6 domains
                     of the 23S rRNA in the assembled 50S subunit and ribosome;
                     mutations in this gene result in erythromycin resistance;
                     located near peptidyl-transferase center"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="NP_357788.1"
                     /db_xref="GI:15902238"
                     /db_xref="GeneID:932936"
     gene            199251..199904
                     /gene="rpsC"
                     /locus_tag="spr0195"
                     /db_xref="GeneID:933129"
     CDS             199251..199904
                     /gene="rpsC"
                     /locus_tag="spr0195"
                     /note="forms a complex with S10 and S14; binds the lower
                     part of the 30S subunit head and the mRNA in the complete
                     ribosome to position it for translation"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="NP_357789.1"
                     /db_xref="GI:15902239"
                     /db_xref="GeneID:933129"
     gene            199908..200321
                     /gene="rplP"
                     /locus_tag="spr0196"
                     /db_xref="GeneID:933103"
     CDS             199908..200321
                     /gene="rplP"
                     /locus_tag="spr0196"
                     /note="located in the peptidyl transferase center and may
                     be involved in peptidyl transferase activity; similar to
                     archaeal L10e"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="NP_357790.1"
                     /db_xref="GI:15902240"
                     /db_xref="GeneID:933103"
     gene            200331..200537
                     /gene="rpmC"
                     /locus_tag="spr0197"
                     /db_xref="GeneID:933478"
     CDS             200331..200537
                     /gene="rpmC"
                     /locus_tag="spr0197"
                     /note="one of the stabilizing components for the large
                     ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="NP_357791.1"
                     /db_xref="GI:15902241"
                     /db_xref="GeneID:933478"
     gene            200562..200822
                     /gene="rpsQ"
                     /locus_tag="spr0198"
                     /db_xref="GeneID:932999"
     CDS             200562..200822
                     /gene="rpsQ"
                     /locus_tag="spr0198"
                     /note="primary binding protein; helps mediate assembly;
                     involved in translation fidelity"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="NP_357792.1"
                     /db_xref="GI:15902242"
                     /db_xref="GeneID:932999"
     gene            200848..201216
                     /gene="rplN"
                     /locus_tag="spr0199"
                     /db_xref="GeneID:933923"
     CDS             200848..201216
                     /gene="rplN"
                     /locus_tag="spr0199"
                     /note="binds to the 23S rRNA between the centers for
                     peptidyl transferase and GTPase"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="NP_357793.1"
                     /db_xref="GI:15902243"
                     /db_xref="GeneID:933923"
     gene            201294..201599
                     /gene="rplX"
                     /locus_tag="spr0200"
                     /db_xref="GeneID:933260"
     CDS             201294..201599
                     /gene="rplX"
                     /locus_tag="spr0200"
                     /note="assembly initiator protein; binds to 5' end of 23S
                     rRNA and nucleates assembly of the 50S; surrounds
                     polypeptide exit tunnel"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="NP_357794.1"
                     /db_xref="GI:15902244"
                     /db_xref="GeneID:933260"
     gene            201623..202165
                     /gene="rplE"
                     /locus_tag="spr0201"
                     /db_xref="GeneID:932791"
     CDS             201623..202165
                     /gene="rplE"
                     /locus_tag="spr0201"
                     /note="part of 50S and 5S/L5/L18/L25 subcomplex; contacts
                     5S rRNA and P site tRNA; forms a bridge to the 30S subunit
                     in the ribosome by binding to S13"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="NP_357795.1"
                     /db_xref="GI:15902245"
                     /db_xref="GeneID:932791"
     gene            202183..202452
                     /gene="rpsN"
                     /locus_tag="spr0202"
                     /db_xref="GeneID:933061"
     CDS             202183..202452
                     /gene="rpsN"
                     /locus_tag="spr0202"
                     /note="located in the peptidyl transferase center and
                     involved in assembly of 30S ribosome subunit; similar to
                     what is observed with proteins L31 and L33, some proteins
                     in this family contain CXXC motifs that are involved in
                     zinc binding; if two copies are present in a genome, then
                     the duplicated copy appears to have lost the zinc-binding
                     motif and is instead regulated by zinc; the proteins in
                     this group do not appear to have the zinc-binding motif"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="NP_357796.1"
                     /db_xref="GI:15902246"
                     /db_xref="GeneID:933061"
     gene            202737..203135
                     /gene="rpsH"
                     /locus_tag="spr0203"
                     /db_xref="GeneID:933398"
     CDS             202737..203135
                     /gene="rpsH"
                     /locus_tag="spr0203"
                     /note="binds directly to 16S rRNA central domain where it
                     helps coordinate assembly of the platform of the 30S
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="NP_357797.1"
                     /db_xref="GI:15902247"
                     /db_xref="GeneID:933398"
     gene            203327..203863
                     /gene="rplF"
                     /locus_tag="spr0204"
                     /db_xref="GeneID:933505"
     CDS             203327..203863
                     /gene="rplF"
                     /locus_tag="spr0204"
                     /note="ribosomal protein L6 appears to have arisen as a
                     result of an ancient gene duplication as based on
                     structural comparison of the Bacillus stearothermophilus
                     protein; RNA-binding appears to be in the C-terminal
                     domain; mutations in the L6 gene confer resistance to
                     aminoglycoside antibiotics such as gentamicin and these
                     occur in truncations of the C-terminal domain; it has been
                     localized to a region between the base of the L7/L12 stalk
                     and the central protuberance"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="NP_357798.1"
                     /db_xref="GI:15902248"
                     /db_xref="GeneID:933505"
     gene            203947..204303
                     /gene="rplR"
                     /locus_tag="spr0205"
                     /db_xref="GeneID:933766"
     CDS             203947..204303
                     /gene="rplR"
                     /locus_tag="spr0205"
                     /note="binds 5S rRNA along with protein L5 and L25"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="NP_357799.1"
                     /db_xref="GI:15902249"
                     /db_xref="GeneID:933766"
     gene            204321..204815
                     /gene="rpsE"
                     /locus_tag="spr0206"
                     /db_xref="GeneID:933812"
     CDS             204321..204815
                     /gene="rpsE"
                     /locus_tag="spr0206"
                     /note="located at the back of the 30S subunit body where
                     it stabilizes the conformation of the head with respect to
                     the body; contacts S4 and S8; with S4 and S12 plays a role
                     in translational accuracy; mutations in this gene result
                     in spectinomycin resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="NP_357800.1"
                     /db_xref="GI:15902250"
                     /db_xref="GeneID:933812"
     gene            204829..205011
                     /gene="rpmD"
                     /locus_tag="spr0207"
                     /db_xref="GeneID:933890"
     CDS             204829..205011
                     /gene="rpmD"
                     /locus_tag="spr0207"
                     /note="L30 binds domain II of the 23S rRNA and the 5S
                     rRNA; similar to eukaryotic protein L7"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="NP_357801.1"
                     /db_xref="GI:15902251"
                     /db_xref="GeneID:933890"
     gene            205156..205596
                     /gene="rplO"
                     /locus_tag="spr0208"
                     /db_xref="GeneID:933940"
     CDS             205156..205596
                     /gene="rplO"
                     /locus_tag="spr0208"
                     /note="late assembly protein"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="NP_357802.1"
                     /db_xref="GI:15902252"
                     /db_xref="GeneID:933940"
     gene            205609..206919
                     /gene="secY"
                     /locus_tag="spr0209"
                     /db_xref="GeneID:933437"
     CDS             205609..206919
                     /gene="secY"
                     /locus_tag="spr0209"
                     /note="forms heterotrimeric complex in the membrane; in
                     bacteria the complex consists of SecY which forms the
                     channel pore and SecE and SecG; the SecG subunit is not
                     essential; in bacteria translocation is driven via the
                     SecA ATPase"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="NP_357803.1"
                     /db_xref="GI:15902253"
                     /db_xref="GeneID:933437"
     gene            207070..207708
                     /gene="adk"
                     /locus_tag="spr0210"
                     /db_xref="GeneID:933789"
     CDS             207070..207708
                     /gene="adk"
                     /locus_tag="spr0210"
                     /EC_number="2.7.4.3"
                     /note="essential enzyme that recycles AMP in active cells;
                     converts ATP and AMP to two molecules of ADP"
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="NP_357804.1"
                     /db_xref="GI:15902254"
                     /db_xref="GeneID:933789"
     gene            207825..208043
                     /gene="infA"
                     /locus_tag="spr0211"
                     /db_xref="GeneID:932927"
     CDS             207825..208043
                     /gene="infA"
                     /locus_tag="spr0211"
                     /note="stimulates the activities of the other two
                     initiation factors, IF-2 and IF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="NP_357805.2"
                     /db_xref="GI:555247342"
                     /db_xref="GeneID:932927"
     gene            208068..208184
                     /gene="rpmJ"
                     /locus_tag="spr0212"
                     /db_xref="GeneID:933957"
     CDS             208068..208184
                     /gene="rpmJ"
                     /locus_tag="spr0212"
                     /note="smallest protein in the large subunit; similar to
                     what is found with protein L31 and L33 several bacterial
                     genomes contain paralogs which may be regulated by zinc;
                     the protein from Thermus thermophilus has a zinc-binding
                     motif and contains a bound zinc ion; the proteins in this
                     group have the motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="NP_357806.1"
                     /db_xref="GI:15902256"
                     /db_xref="GeneID:933957"
     gene            208202..208567
                     /gene="rpsM"
                     /locus_tag="spr0213"
                     /db_xref="GeneID:933973"
     CDS             208202..208567
                     /gene="rpsM"
                     /locus_tag="spr0213"
                     /note="located at the top of the head of the 30S subunit,
                     it contacts several helices of the 16S rRNA; makes contact
                     with the large subunit via RNA-protein interactions and
                     via protein-protein interactions with L5; contacts P-site
                     tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="NP_357807.1"
                     /db_xref="GI:15902257"
                     /db_xref="GeneID:933973"
     gene            208585..208968
                     /gene="rpsK"
                     /locus_tag="spr0214"
                     /db_xref="GeneID:933403"
     CDS             208585..208968
                     /gene="rpsK"
                     /locus_tag="spr0214"
                     /note="located on the platform of the 30S subunit, it
                     bridges several disparate RNA helices of the 16S rRNA;
                     forms part of the Shine-Dalgarno cleft in the 70S
                     ribosome; interacts with S7 and S18 and IF-3"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="NP_357808.1"
                     /db_xref="GI:15902258"
                     /db_xref="GeneID:933403"
     gene            209011..209946
                     /gene="rpoA"
                     /locus_tag="spr0215"
                     /db_xref="GeneID:933822"
     CDS             209011..209946
                     /gene="rpoA"
                     /locus_tag="spr0215"
                     /EC_number="2.7.7.6"
                     /note="catalyzes the transcription of DNA into RNA using
                     the four ribonucleoside triphosphates as substrates.
                     Dimerization of the alpha subunit is the first step in the
                     sequential assembly of subunits to form the holoenzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="NP_357809.1"
                     /db_xref="GI:15902259"
                     /db_xref="GeneID:933822"
     gene            209958..210344
                     /gene="rplQ"
                     /locus_tag="spr0216"
                     /db_xref="GeneID:933143"
     CDS             209958..210344
                     /gene="rplQ"
                     /locus_tag="spr0216"
                     /note="is a component of the macrolide binding site in the
                     peptidyl transferase center"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="NP_357810.1"
                     /db_xref="GI:15902260"
                     /db_xref="GeneID:933143"
     gene            210609..210875
                     /locus_tag="spr0217"
                     /db_xref="GeneID:933047"
     CDS             210609..210875
                     /locus_tag="spr0217"
                     /note="ACT domain-containing protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357811.2"
                     /db_xref="GI:161410756"
                     /db_xref="GeneID:933047"
     gene            210885..212222
                     /locus_tag="spr0218"
                     /db_xref="GeneID:933558"
     CDS             210885..212222
                     /locus_tag="spr0218"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357812.1"
                     /db_xref="GI:15902262"
                     /db_xref="GeneID:933558"
     gene            212409..213158
                     /gene="gpmB"
                     /locus_tag="spr0219"
                     /db_xref="GeneID:933096"
     CDS             212409..213158
                     /gene="gpmB"
                     /locus_tag="spr0219"
                     /EC_number="5.4.2.1"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="NP_357813.1"
                     /db_xref="GI:15902263"
                     /db_xref="GeneID:933096"
     gene            complement(213261..214295)
                     /gene="ABC-MSP"
                     /locus_tag="spr0220"
                     /db_xref="GeneID:933873"
     CDS             complement(213261..214295)
                     /gene="ABC-MSP"
                     /locus_tag="spr0220"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="NP_357814.1"
                     /db_xref="GI:15902264"
                     /db_xref="GeneID:933873"
     gene            complement(214280..214906)
                     /gene="ABC-MSP"
                     /locus_tag="spr0221"
                     /db_xref="GeneID:933823"
     CDS             complement(214280..214906)
                     /gene="ABC-MSP"
                     /locus_tag="spr0221"
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="NP_357815.1"
                     /db_xref="GI:15902265"
                     /db_xref="GeneID:933823"
     gene            complement(214896..215987)
                     /gene="ABC-NBD"
                     /locus_tag="spr0222"
                     /db_xref="GeneID:933981"
     CDS             complement(214896..215987)
                     /gene="ABC-NBD"
                     /locus_tag="spr0222"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_357816.1"
                     /db_xref="GI:15902266"
                     /db_xref="GeneID:933981"
     gene            complement(216000..216707)
                     /gene="ABC-SBP-truncation"
                     /locus_tag="spr0223"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933084"
     repeat_region   216419..216525
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   217198..217296
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            complement(217339..217536)
                     /locus_tag="spr0225"
                     /db_xref="GeneID:932975"
     CDS             complement(217339..217536)
                     /locus_tag="spr0225"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357819.1"
                     /db_xref="GI:15902269"
                     /db_xref="GeneID:932975"
     gene            complement(217611..218387)
                     /gene="pflE"
                     /locus_tag="spr0226"
                     /db_xref="GeneID:933787"
     CDS             complement(217611..218387)
                     /gene="pflE"
                     /locus_tag="spr0226"
                     /EC_number="1.97.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate-lyase 3"
                     /protein_id="NP_357820.1"
                     /db_xref="GI:15902270"
                     /db_xref="GeneID:933787"
     gene            218461..219255
                     /gene="deoR"
                     /locus_tag="spr0227"
                     /db_xref="GeneID:933802"
     CDS             218461..219255
                     /gene="deoR"
                     /locus_tag="spr0227"
                     /codon_start=1
                     /transl_table=11
                     /product="DEOR-type transcriptional regulator"
                     /protein_id="NP_357821.1"
                     /db_xref="GI:15902271"
                     /db_xref="GeneID:933802"
     gene            219268..220248
                     /locus_tag="spr0228"
                     /db_xref="GeneID:932868"
     CDS             219268..220248
                     /locus_tag="spr0228"
                     /note="Resembles sorbitol operon regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357822.1"
                     /db_xref="GI:15902272"
                     /db_xref="GeneID:932868"
     gene            220443..220763
                     /gene="PTS-EIIA"
                     /locus_tag="spr0229"
                     /db_xref="GeneID:933017"
     CDS             220443..220763
                     /gene="PTS-EIIA"
                     /locus_tag="spr0229"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_357823.1"
                     /db_xref="GI:15902273"
                     /db_xref="GeneID:933017"
     gene            220809..221117
                     /gene="PTS-EIIB"
                     /locus_tag="spr0230"
                     /db_xref="GeneID:933950"
     CDS             220809..221117
                     /gene="PTS-EIIB"
                     /locus_tag="spr0230"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_357824.1"
                     /db_xref="GI:15902274"
                     /db_xref="GeneID:933950"
     gene            221110..222432
                     /gene="PTS-EIIC"
                     /locus_tag="spr0231"
                     /db_xref="GeneID:934634"
     CDS             221110..222432
                     /gene="PTS-EIIC"
                     /locus_tag="spr0231"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_357825.1"
                     /db_xref="GI:15902275"
                     /db_xref="GeneID:934634"
     gene            222574..225021
                     /gene="pflF"
                     /locus_tag="spr0232"
                     /db_xref="GeneID:932996"
     CDS             222574..225021
                     /gene="pflF"
                     /locus_tag="spr0232"
                     /EC_number="2.3.1.54"
                     /codon_start=1
                     /transl_table=11
                     /product="formate acetyltransferase 3"
                     /protein_id="NP_357826.1"
                     /db_xref="GI:15902276"
                     /db_xref="GeneID:932996"
     gene            225040..225708
                     /gene="talC"
                     /locus_tag="spr0233"
                     /db_xref="GeneID:933429"
     CDS             225040..225708
                     /gene="talC"
                     /locus_tag="spr0233"
                     /EC_number="2.2.1.2"
                     /note="similar to transaldolase from Escherichia coli;
                     many organisms have multiple copies"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="NP_357827.1"
                     /db_xref="GI:15902277"
                     /db_xref="GeneID:933429"
     gene            225726..226814
                     /gene="gldA"
                     /locus_tag="spr0234"
                     /db_xref="GeneID:934143"
     CDS             225726..226814
                     /gene="gldA"
                     /locus_tag="spr0234"
                     /EC_number="1.1.1.6"
                     /note="forms dimers and octamers; involved in conversion
                     of glycerol to dihydroxy-acetone"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="NP_357828.1"
                     /db_xref="GI:15902278"
                     /db_xref="GeneID:934143"
     repeat_region   complement(226873..226979)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     gene            227269..229770
                     /gene="leuS"
                     /locus_tag="spr0235"
                     /db_xref="GeneID:934057"
     CDS             227269..229770
                     /gene="leuS"
                     /locus_tag="spr0235"
                     /EC_number="6.1.1.4"
                     /note="leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA
                     synthetase; charges leucine by linking carboxyl group to
                     alpha-phosphate of ATP and then transfers
                     aminoacyl-adenylate to its tRNA; due to the large number
                     of codons that tRNA(Leu) recognizes, the leucyl-tRNA
                     synthetase does not recognize the anticodon loop of the
                     tRNA, but instead recognition is dependent on a conserved
                     discriminator base A37 and a long arm; an editing domain
                     hydrolyzes misformed products; in Methanothermobacter
                     thermautotrophicus this enzyme associates with prolyl-tRNA
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl-tRNA synthetase"
                     /protein_id="NP_357829.1"
                     /db_xref="GI:15902279"
                     /db_xref="GeneID:934057"
     gene            229964..230659
                     /locus_tag="spr0236"
                     /db_xref="GeneID:933481"
     CDS             229964..230659
                     /locus_tag="spr0236"
                     /note="Similar to acetyltransferases, including
                     N-acetylases of ribosomal proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357830.1"
                     /db_xref="GI:15902280"
                     /db_xref="GeneID:933481"
     gene            230671..231087
                     /locus_tag="spr0237"
                     /db_xref="GeneID:934635"
     CDS             230671..231087
                     /locus_tag="spr0237"
                     /note="Similar to histone acetyltransferase HPA2 and
                     related acetyltransferases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357831.1"
                     /db_xref="GI:15902281"
                     /db_xref="GeneID:934635"
     gene            232128..233126
                     /gene="ruvB"
                     /locus_tag="spr0238"
                     /db_xref="GeneID:934147"
     CDS             232128..233126
                     /gene="ruvB"
                     /locus_tag="spr0238"
                     /EC_number="3.1.22.4"
                     /note="promotes strand exchange during homologous
                     recombination; RuvAB complex promotes branch migration;
                     RuvABC complex scans the DNA during branch migration and
                     resolves Holliday junctions at consensus sequences; forms
                     hexameric rings around opposite DNA arms; requires ATP for
                     branch migration and orientation of RuvAB complex
                     determines direction of migration"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction DNA helicase RuvB"
                     /protein_id="NP_357832.1"
                     /db_xref="GI:15902282"
                     /db_xref="GeneID:934147"
     gene            233107..233679
                     /locus_tag="spr0239"
                     /db_xref="GeneID:933735"
     CDS             233107..233679
                     /locus_tag="spr0239"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357833.1"
                     /db_xref="GI:15902283"
                     /db_xref="GeneID:933735"
     gene            233892..234668
                     /gene="uppS"
                     /locus_tag="spr0240"
                     /db_xref="GeneID:934063"
     CDS             233892..234668
                     /gene="uppS"
                     /locus_tag="spr0240"
                     /EC_number="2.5.1.31"
                     /note="catalyzes the formation of undecaprenyl
                     pyrophosphate from isopentenyl pyrophosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate synthase"
                     /protein_id="NP_357834.1"
                     /db_xref="GI:15902284"
                     /db_xref="GeneID:934063"
     gene            234677..235480
                     /gene="cdsA"
                     /locus_tag="spr0241"
                     /db_xref="GeneID:934160"
     CDS             234677..235480
                     /gene="cdsA"
                     /locus_tag="spr0241"
                     /EC_number="2.7.7.41"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="NP_357835.1"
                     /db_xref="GI:15902285"
                     /db_xref="GeneID:934160"
     gene            235502..236761
                     /gene="eep"
                     /locus_tag="spr0242"
                     /db_xref="GeneID:933841"
     CDS             235502..236761
                     /gene="eep"
                     /locus_tag="spr0242"
                     /codon_start=1
                     /transl_table=11
                     /product="determinant for enhanced expression of
                     pheromone"
                     /protein_id="NP_357836.1"
                     /db_xref="GI:15902286"
                     /db_xref="GeneID:933841"
     gene            236774..238627
                     /gene="proS"
                     /locus_tag="spr0243"
                     /db_xref="GeneID:933853"
     CDS             236774..238627
                     /gene="proS"
                     /locus_tag="spr0243"
                     /EC_number="6.1.1.15"
                     /note="catalyzes the formation of prolyl-tRNA(Pro) from
                     proline and tRNA(Pro)"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase"
                     /protein_id="NP_357837.1"
                     /db_xref="GI:15902287"
                     /db_xref="GeneID:933853"
     gene            238727..240106
                     /gene="bglA"
                     /locus_tag="spr0244"
                     /db_xref="GeneID:932970"
     CDS             238727..240106
                     /gene="bglA"
                     /locus_tag="spr0244"
                     /EC_number="3.2.1.21"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="NP_357838.1"
                     /db_xref="GI:15902288"
                     /db_xref="GeneID:932970"
     gene            240298..242106
                     /gene="glmS"
                     /locus_tag="spr0245"
                     /db_xref="GeneID:932810"
     CDS             240298..242106
                     /gene="glmS"
                     /locus_tag="spr0245"
                     /EC_number="2.6.1.16"
                     /note="Catalyzes the first step in hexosamine metabolism,
                     converting fructose-6P into glucosamine-6P using glutamine
                     as a nitrogen source"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine--fructose-6-phosphate
                     aminotransferase"
                     /protein_id="NP_357839.1"
                     /db_xref="GI:15902289"
                     /db_xref="GeneID:932810"
     gene            242225..243274
                     /locus_tag="spr0246"
                     /db_xref="GeneID:933939"
     CDS             242225..243274
                     /locus_tag="spr0246"
                     /note="Similar to coenzyme F420-dependent N5,N10-methylene
                     tetrahydromethanopterin reductase and and related
                     flavin-dependent oxidoreductases"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357840.1"
                     /db_xref="GI:15902290"
                     /db_xref="GeneID:933939"
     gene            complement(243374..247144)
                     /gene="pulA"
                     /locus_tag="spr0247"
                     /db_xref="GeneID:933840"
     CDS             complement(243374..247144)
                     /gene="pulA"
                     /locus_tag="spr0247"
                     /EC_number="3.2.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline amylopullulanase"
                     /protein_id="NP_357841.1"
                     /db_xref="GI:15902291"
                     /db_xref="GeneID:933840"
     gene            247561..247974
                     /gene="rpsL"
                     /locus_tag="spr0248"
                     /db_xref="GeneID:934814"
     CDS             247561..247974
                     /gene="rpsL"
                     /locus_tag="spr0248"
                     /note="interacts with and stabilizes bases of the 16S rRNA
                     that are involved in tRNA selection in the A site and with
                     the mRNA backbone; located at the interface of the 30S and
                     50S subunits, it traverses the body of the 30S subunit
                     contacting proteins on the other side; mutations in the
                     S12 gene confer streptomycin resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="NP_357842.1"
                     /db_xref="GI:15902292"
                     /db_xref="GeneID:934814"
     gene            247994..248464
                     /gene="rpsG"
                     /locus_tag="spr0249"
                     /db_xref="GeneID:933759"
     CDS             247994..248464
                     /gene="rpsG"
                     /locus_tag="spr0249"
                     /note="binds directly to 16S rRNA where it nucleates
                     assembly of the head domain of the 30S subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="NP_357843.1"
                     /db_xref="GI:15902293"
                     /db_xref="GeneID:933759"
     gene            248889..250970
                     /gene="fusA"
                     /locus_tag="spr0250"
                     /db_xref="GeneID:933055"
     CDS             248889..250970
                     /gene="fusA"
                     /locus_tag="spr0250"
                     /note="EF-G; promotes GTP-dependent translocation of the
                     ribosome during translation; many organisms have multiple
                     copies of this gene"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="NP_357844.1"
                     /db_xref="GI:15902294"
                     /db_xref="GeneID:933055"
     gene            251074..255465
                     /gene="polC"
                     /locus_tag="spr0251"
                     /db_xref="GeneID:934637"
     CDS             251074..255465
                     /gene="polC"
                     /locus_tag="spr0251"
                     /EC_number="2.7.7.7"
                     /note="catalyzes DNA-template-directed extension of the
                     3'- end of a DNA strand by one nucleotide at a time;
                     required for leading strand synthesis; PolC exhibits 3' to
                     5' exonuclease activity"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III PolC"
                     /protein_id="NP_357845.1"
                     /db_xref="GI:15902295"
                     /db_xref="GeneID:934637"
     gene            255567..255830
                     /locus_tag="spr0252"
                     /db_xref="GeneID:933022"
     CDS             255567..255830
                     /locus_tag="spr0252"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357846.1"
                     /db_xref="GI:15902296"
                     /db_xref="GeneID:933022"
     gene            255823..256101
                     /locus_tag="spr0253"
                     /db_xref="GeneID:932971"
     CDS             255823..256101
                     /locus_tag="spr0253"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357847.1"
                     /db_xref="GI:15902297"
                     /db_xref="GeneID:932971"
     gene            256122..256274
                     /locus_tag="spr0253a"
                     /db_xref="GeneID:19592985"
     CDS             256122..256274
                     /locus_tag="spr0253a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008869148.1"
                     /db_xref="GI:651852199"
                     /db_xref="GeneID:19592985"
     gene            256296..257537
                     /gene="pepS"
                     /locus_tag="spr0254"
                     /db_xref="GeneID:934836"
     CDS             256296..257537
                     /gene="pepS"
                     /locus_tag="spr0254"
                     /EC_number="3.4.11.-"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="NP_357848.1"
                     /db_xref="GI:15902298"
                     /db_xref="GeneID:934836"
     gene            257547..257777
                     /locus_tag="spr0255"
                     /db_xref="GeneID:934172"
     CDS             257547..257777
                     /locus_tag="spr0255"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357849.1"
                     /db_xref="GI:15902299"
                     /db_xref="GeneID:934172"
     repeat_region   complement(257791..258030)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbbba"
     gene            258090..258812
                     /gene="rsuA"
                     /locus_tag="spr0256"
                     /db_xref="GeneID:933942"
     CDS             258090..258812
                     /gene="rsuA"
                     /locus_tag="spr0256"
                     /EC_number="4.2.1.70"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal small subunit pseudouridine synthase
                     A"
                     /protein_id="NP_357850.1"
                     /db_xref="GI:15902300"
                     /db_xref="GeneID:933942"
     repeat_region   complement(258822..258925)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            258893..259057
                     /locus_tag="spr0257"
                     /db_xref="GeneID:934764"
     CDS             258893..259057
                     /locus_tag="spr0257"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357851.1"
                     /db_xref="GI:15902301"
                     /db_xref="GeneID:934764"
     gene            259029..260363
                     /gene="pepC"
                     /locus_tag="spr0258"
                     /db_xref="GeneID:934645"
     CDS             259029..260363
                     /gene="pepC"
                     /locus_tag="spr0258"
                     /EC_number="3.4.22.-"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="NP_357852.1"
                     /db_xref="GI:15902302"
                     /db_xref="GeneID:934645"
     gene            complement(260419..261330)
                     /gene="manN"
                     /locus_tag="spr0259"
                     /db_xref="GeneID:934837"
     CDS             complement(260419..261330)
                     /gene="manN"
                     /locus_tag="spr0259"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose-specific transporter subunit
                     EIID"
                     /protein_id="NP_357853.1"
                     /db_xref="GI:15902303"
                     /db_xref="GeneID:934837"
     gene            complement(261354..262157)
                     /gene="manM"
                     /locus_tag="spr0260"
                     /db_xref="GeneID:934638"
     CDS             complement(261354..262157)
                     /gene="manM"
                     /locus_tag="spr0260"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose-specific transporter subunit
                     IIC"
                     /protein_id="NP_357854.1"
                     /db_xref="GI:15902304"
                     /db_xref="GeneID:934638"
     gene            complement(262185..263183)
                     /gene="manL"
                     /locus_tag="spr0261"
                     /db_xref="GeneID:934647"
     CDS             complement(262185..263183)
                     /gene="manL"
                     /locus_tag="spr0261"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose-specific transporter subunit
                     IIAB"
                     /protein_id="NP_357855.1"
                     /db_xref="GI:15902305"
                     /db_xref="GeneID:934647"
     gene            complement(263358..264377)
                     /gene="adhP"
                     /locus_tag="spr0262"
                     /gene_synonym="adhA"
                     /db_xref="GeneID:934639"
     CDS             complement(263358..264377)
                     /gene="adhP"
                     /locus_tag="spr0262"
                     /gene_synonym="adhA"
                     /EC_number="1.1.1.1"
                     /note="similar to zinc-dependent eukaryotic ADH enzymes
                     and distinct from fermentative ADHs"
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="NP_357856.1"
                     /db_xref="GI:15902306"
                     /db_xref="GeneID:934639"
     repeat_region   264594..264706
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(264716..265528)
                     /locus_tag="spr0263"
                     /db_xref="GeneID:934654"
     CDS             complement(264716..265528)
                     /locus_tag="spr0263"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_357857.1"
                     /db_xref="GI:15902307"
                     /db_xref="GeneID:934654"
     gene            265664..267136
                     /locus_tag="spr0264"
                     /db_xref="GeneID:934650"
     CDS             265664..267136
                     /locus_tag="spr0264"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/uracil permease"
                     /protein_id="NP_357858.1"
                     /db_xref="GI:15902308"
                     /db_xref="GeneID:934650"
     gene            267187..267897
                     /locus_tag="spr0265"
                     /db_xref="GeneID:934648"
     CDS             267187..267897
                     /locus_tag="spr0265"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357859.1"
                     /db_xref="GI:15902309"
                     /db_xref="GeneID:934648"
     gene            268022..268966
                     /gene="sulA"
                     /locus_tag="spr0266"
                     /db_xref="GeneID:934662"
     CDS             268022..268966
                     /gene="sulA"
                     /locus_tag="spr0266"
                     /EC_number="2.5.1.15"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="NP_357860.1"
                     /db_xref="GI:15902310"
                     /db_xref="GeneID:934662"
     gene            268968..270290
                     /gene="sulB"
                     /locus_tag="spr0267"
                     /db_xref="GeneID:934661"
     CDS             268968..270290
                     /gene="sulB"
                     /locus_tag="spr0267"
                     /EC_number="6.3.2.12"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate synthetase"
                     /protein_id="NP_357861.1"
                     /db_xref="GI:15902311"
                     /db_xref="GeneID:934661"
     gene            270271..270825
                     /gene="folE"
                     /locus_tag="spr0268"
                     /db_xref="GeneID:934652"
     CDS             270271..270825
                     /gene="folE"
                     /locus_tag="spr0268"
                     /EC_number="3.5.4.16"
                     /note="involved in the first step of tetrahydrofolate
                     biosynthesis; catalyzes the formation of formate and
                     2-amino-4-hydroxy-6-(erythro-1,2,
                     3-trihydroxypropyl)dihydropteridine triphosphate from GTP
                     and water; forms a homopolymer"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I"
                     /protein_id="NP_357862.1"
                     /db_xref="GI:15902312"
                     /db_xref="GeneID:934652"
     gene            270868..271680
                     /gene="sulD"
                     /locus_tag="spr0269"
                     /db_xref="GeneID:934668"
     CDS             270868..271680
                     /gene="sulD"
                     /locus_tag="spr0269"
                     /EC_number="2.7.6.3"
                     /EC_number="4.1.2.25"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folate synthesis protein"
                     /protein_id="NP_357863.1"
                     /db_xref="GI:15902313"
                     /db_xref="GeneID:934668"
     gene            complement(271725..272096)
                     /locus_tag="spr0270"
                     /db_xref="GeneID:934659"
     CDS             complement(271725..272096)
                     /locus_tag="spr0270"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357864.1"
                     /db_xref="GI:15902314"
                     /db_xref="GeneID:934659"
     gene            272399..272845
                     /gene="rplM"
                     /locus_tag="spr0271"
                     /db_xref="GeneID:934656"
     CDS             272399..272845
                     /gene="rplM"
                     /locus_tag="spr0271"
                     /note="in Escherichia coli this protein is one of the
                     earliest assembly proteins in the large subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="NP_357865.1"
                     /db_xref="GI:15902315"
                     /db_xref="GeneID:934656"
     gene            272865..273257
                     /gene="rpsI"
                     /locus_tag="spr0272"
                     /db_xref="GeneID:934684"
     CDS             272865..273257
                     /gene="rpsI"
                     /locus_tag="spr0272"
                     /note="forms a direct contact with the tRNA during
                     translation"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="NP_357866.1"
                     /db_xref="GI:15902316"
                     /db_xref="GeneID:934684"
     repeat_region   complement(273503..273606)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            273944..274309
                     /locus_tag="spr0275"
                     /db_xref="GeneID:934666"
     CDS             273944..274309
                     /locus_tag="spr0275"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357869.1"
                     /db_xref="GI:15902319"
                     /db_xref="GeneID:934666"
     gene            274499..275935
                     /gene="celA"
                     /locus_tag="spr0276"
                     /db_xref="GeneID:934676"
     CDS             274499..275935
                     /gene="celA"
                     /locus_tag="spr0276"
                     /EC_number="3.2.1.86"
                     /note="converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose
                     to glucose and glucose 6-phosphate; required for
                     cellobiose uptake and metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="NP_357870.1"
                     /db_xref="GI:15902320"
                     /db_xref="GeneID:934676"
     gene            275987..276226
                     /locus_tag="spr0277"
                     /db_xref="GeneID:934690"
     CDS             275987..276226
                     /locus_tag="spr0277"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357871.1"
                     /db_xref="GI:15902321"
                     /db_xref="GeneID:934690"
     gene            276356..276670
                     /gene="celB"
                     /locus_tag="spr0278"
                     /db_xref="GeneID:934677"
     CDS             276356..276670
                     /gene="celB"
                     /locus_tag="spr0278"
                     /EC_number="2.7.1.69"
                     /note="required for cellobiose uptake and metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system cellobiose transporter subunit IIB"
                     /protein_id="NP_357872.2"
                     /db_xref="GI:161410755"
                     /db_xref="GeneID:934677"
     gene            276788..278767
                     /gene="bglG"
                     /locus_tag="spr0279"
                     /db_xref="GeneID:934694"
     CDS             276788..278767
                     /gene="bglG"
                     /locus_tag="spr0279"
                     /codon_start=1
                     /transl_table=11
                     /product="BigG family transcription antiterminator"
                     /protein_id="NP_357873.1"
                     /db_xref="GI:15902323"
                     /db_xref="GeneID:934694"
     gene            278777..279091
                     /gene="celC"
                     /locus_tag="spr0280"
                     /db_xref="GeneID:934696"
     CDS             278777..279091
                     /gene="celC"
                     /locus_tag="spr0280"
                     /EC_number="2.7.1.69"
                     /note="required for cellobiose uptake and metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system cellobiose transporter subunit IIA"
                     /protein_id="NP_357874.1"
                     /db_xref="GI:15902324"
                     /db_xref="GeneID:934696"
     gene            279110..279616
                     /locus_tag="spr0281"
                     /db_xref="GeneID:934682"
     CDS             279110..279616
                     /locus_tag="spr0281"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357875.1"
                     /db_xref="GI:15902325"
                     /db_xref="GeneID:934682"
     gene            279696..281042
                     /gene="celD"
                     /locus_tag="spr0282"
                     /db_xref="GeneID:934687"
     CDS             279696..281042
                     /gene="celD"
                     /locus_tag="spr0282"
                     /EC_number="2.7.1.69"
                     /note="required for cellobiose uptake and metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system cellobiose transporter subunit IIC"
                     /protein_id="NP_357876.1"
                     /db_xref="GI:15902326"
                     /db_xref="GeneID:934687"
     gene            281424..281600
                     /locus_tag="spr0283"
                     /db_xref="GeneID:934700"
     CDS             281424..281600
                     /locus_tag="spr0283"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357877.1"
                     /db_xref="GI:15902327"
                     /db_xref="GeneID:934700"
     gene            282002..284215
                     /gene="xylS"
                     /locus_tag="spr0284"
                     /db_xref="GeneID:934686"
     CDS             282002..284215
                     /gene="xylS"
                     /locus_tag="spr0284"
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Alpha-xylosidase"
                     /protein_id="NP_357878.1"
                     /db_xref="GI:15902328"
                     /db_xref="GeneID:934686"
     gene            complement(284437..284913)
                     /gene="basA"
                     /locus_tag="spr0285"
                     /db_xref="GeneID:934692"
     CDS             complement(284437..284913)
                     /gene="basA"
                     /locus_tag="spr0285"
                     /EC_number="1.11.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="NP_357879.1"
                     /db_xref="GI:15902329"
                     /db_xref="GeneID:934692"
     gene            285103..288339
                     /gene="hysA"
                     /locus_tag="spr0286"
                     /db_xref="GeneID:934705"
     CDS             285103..288339
                     /gene="hysA"
                     /locus_tag="spr0286"
                     /EC_number="4.2.2.1"
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="NP_357880.1"
                     /db_xref="GI:15902330"
                     /db_xref="GeneID:934705"
     repeat_region   complement(289173..289279)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(289483..290112)
                     /gene="kdgA"
                     /locus_tag="spr0287"
                     /db_xref="GeneID:934703"
     CDS             complement(289483..290112)
                     /gene="kdgA"
                     /locus_tag="spr0287"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /note="catalyzes the formation of pyruvate and glyoxylate
                     from 4-hydroxy-2-oxoglutarate; or pyruvate and
                     D-glyceraldehyde 3-phosphate from
                     2-dehydro-3-deoxy-D-glyconate 6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="keto-hydroxyglutarate-aldolase/keto-deoxy-
                     phosphogluconate aldolase"
                     /protein_id="NP_357881.1"
                     /db_xref="GI:15902331"
                     /db_xref="GeneID:934703"
     gene            complement(290122..291123)
                     /gene="kdgK"
                     /locus_tag="spr0288"
                     /db_xref="GeneID:934712"
     CDS             complement(290122..291123)
                     /gene="kdgK"
                     /locus_tag="spr0288"
                     /EC_number="2.7.1.45"
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate kinase"
                     /protein_id="NP_357882.1"
                     /db_xref="GI:15902332"
                     /db_xref="GeneID:934712"
     gene            complement(291154..291795)
                     /locus_tag="spr0289"
                     /db_xref="GeneID:934706"
     CDS             complement(291154..291795)
                     /locus_tag="spr0289"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357883.1"
                     /db_xref="GI:15902333"
                     /db_xref="GeneID:934706"
     gene            complement(291814..292629)
                     /gene="gno"
                     /locus_tag="spr0290"
                     /db_xref="GeneID:934713"
     CDS             complement(291814..292629)
                     /gene="gno"
                     /locus_tag="spr0290"
                     /EC_number="1.1.1.69"
                     /note="Involved in the nonphosphorylative, ketogenic
                     oxidation of glucose and oxidizes gluconate to
                     5-ketogluconate"
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="NP_357884.1"
                     /db_xref="GI:15902334"
                     /db_xref="GeneID:934713"
     gene            292900..293334
                     /gene="PTS-EII"
                     /locus_tag="spr0291"
                     /db_xref="GeneID:934720"
     CDS             292900..293334
                     /gene="PTS-EII"
                     /locus_tag="spr0291"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_357885.1"
                     /db_xref="GI:15902335"
                     /db_xref="GeneID:934720"
     gene            293346..294536
                     /gene="ugl"
                     /locus_tag="spr0292"
                     /db_xref="GeneID:934711"
     CDS             293346..294536
                     /gene="ugl"
                     /locus_tag="spr0292"
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronyl hydrolase"
                     /protein_id="NP_357886.1"
                     /db_xref="GI:15902336"
                     /db_xref="GeneID:934711"
     gene            294547..295038
                     /gene="PTS-EII"
                     /locus_tag="spr0293"
                     /db_xref="GeneID:934726"
     CDS             294547..295038
                     /gene="PTS-EII"
                     /locus_tag="spr0293"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_357887.1"
                     /db_xref="GI:15902337"
                     /db_xref="GeneID:934726"
     gene            295053..295832
                     /gene="PTS-EII"
                     /locus_tag="spr0294"
                     /db_xref="GeneID:934729"
     CDS             295053..295832
                     /gene="PTS-EII"
                     /locus_tag="spr0294"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_357888.1"
                     /db_xref="GI:15902338"
                     /db_xref="GeneID:934729"
     gene            295819..296637
                     /gene="PTS-EII"
                     /locus_tag="spr0295"
                     /db_xref="GeneID:934723"
     CDS             295819..296637
                     /gene="PTS-EII"
                     /locus_tag="spr0295"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IID"
                     /protein_id="NP_357889.1"
                     /db_xref="GI:15902339"
                     /db_xref="GeneID:934723"
     gene            296637..296930
                     /locus_tag="spr0296"
                     /db_xref="GeneID:934717"
     CDS             296637..296930
                     /locus_tag="spr0296"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase, YajC subunit"
                     /protein_id="NP_357890.1"
                     /db_xref="GI:15902340"
                     /db_xref="GeneID:934717"
     gene            296952..298853
                     /locus_tag="spr0297"
                     /db_xref="GeneID:934735"
     CDS             296952..298853
                     /locus_tag="spr0297"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357891.1"
                     /db_xref="GI:15902341"
                     /db_xref="GeneID:934735"
     gene            298847..299914
                     /gene="regR"
                     /locus_tag="spr0298"
                     /db_xref="GeneID:934722"
     CDS             298847..299914
                     /gene="regR"
                     /locus_tag="spr0298"
                     /codon_start=1
                     /transl_table=11
                     /product="GalR family transcription regulator"
                     /protein_id="NP_357892.1"
                     /db_xref="GI:15902342"
                     /db_xref="GeneID:934722"
     gene            complement(300360..300602)
                     /locus_tag="spr0300"
                     /db_xref="GeneID:934742"
     CDS             complement(300360..300602)
                     /locus_tag="spr0300"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357894.1"
                     /db_xref="GI:15902344"
                     /db_xref="GeneID:934742"
     gene            complement(300618..300812)
                     /gene="yorfE"
                     /locus_tag="spr0301"
                     /db_xref="GeneID:934732"
     CDS             complement(300618..300812)
                     /gene="yorfE"
                     /locus_tag="spr0301"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_357895.1"
                     /db_xref="GI:15902345"
                     /db_xref="GeneID:934732"
     gene            300978..301928
                     /gene="mraW"
                     /locus_tag="spr0302"
                     /db_xref="GeneID:934733"
     CDS             300978..301928
                     /gene="mraW"
                     /locus_tag="spr0302"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-methyltransferase MraW"
                     /protein_id="NP_357896.1"
                     /db_xref="GI:15902346"
                     /db_xref="GeneID:934733"
     gene            301940..302257
                     /gene="ftsL"
                     /locus_tag="spr0303"
                     /db_xref="GeneID:934757"
     CDS             301940..302257
                     /gene="ftsL"
                     /locus_tag="spr0303"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="NP_357897.1"
                     /db_xref="GI:15902347"
                     /db_xref="GeneID:934757"
     gene            302261..304513
                     /gene="pbpX"
                     /locus_tag="spr0304"
                     /db_xref="GeneID:934744"
     CDS             302261..304513
                     /gene="pbpX"
                     /locus_tag="spr0304"
                     /EC_number="2.3.2.-"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="NP_357898.1"
                     /db_xref="GI:15902348"
                     /db_xref="GeneID:934744"
     gene            304515..305495
                     /gene="mraY"
                     /locus_tag="spr0305"
                     /db_xref="GeneID:934737"
     CDS             304515..305495
                     /gene="mraY"
                     /locus_tag="spr0305"
                     /EC_number="2.7.8.13"
                     /note="First step of the lipid cycle reactions in the
                     biosynthesis of the cell wall peptidoglycan"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="NP_357899.1"
                     /db_xref="GI:15902349"
                     /db_xref="GeneID:934737"
     repeat_region   305595..305645
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            306052..308157
                     /gene="clpL"
                     /locus_tag="spr0307"
                     /db_xref="GeneID:934751"
     CDS             306052..308157
                     /gene="clpL"
                     /locus_tag="spr0307"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit"
                     /protein_id="NP_357901.1"
                     /db_xref="GI:15902351"
                     /db_xref="GeneID:934751"
     gene            complement(308453..308935)
                     /gene="luxS"
                     /locus_tag="spr0308"
                     /db_xref="GeneID:934756"
     CDS             complement(308453..308935)
                     /gene="luxS"
                     /locus_tag="spr0308"
                     /note="catalyzes the hydrolysis of S-ribosylhomocysteine
                     to homocysteine and autoinducer-2"
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="NP_357902.1"
                     /db_xref="GI:15902352"
                     /db_xref="GeneID:934756"
     gene            complement(309030..310514)
                     /locus_tag="spr0309"
                     /db_xref="GeneID:934750"
     CDS             complement(309030..310514)
                     /locus_tag="spr0309"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357903.1"
                     /db_xref="GI:15902353"
                     /db_xref="GeneID:934750"
     gene            310667..312274
                     /gene="dexB"
                     /locus_tag="spr0310"
                     /db_xref="GeneID:934759"
     CDS             310667..312274
                     /gene="dexB"
                     /locus_tag="spr0310"
                     /EC_number="3.2.1.70"
                     /codon_start=1
                     /transl_table=11
                     /product="glucan 1,6-alpha-glucosidase"
                     /protein_id="NP_357904.1"
                     /db_xref="GI:15902354"
                     /db_xref="GeneID:934759"
     gene            312433..312606
                     /locus_tag="spr0311"
                     /db_xref="GeneID:934763"
     CDS             312433..312606
                     /locus_tag="spr0311"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357905.1"
                     /db_xref="GI:15902355"
                     /db_xref="GeneID:934763"
     gene            complement(313115..313462)
                     /locus_tag="spr0312"
                     /db_xref="GeneID:934753"
     CDS             complement(313115..313462)
                     /locus_tag="spr0312"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase B"
                     /protein_id="YP_008869149.2"
                     /db_xref="GI:659670403"
                     /db_xref="GeneID:934753"
     repeat_region   313478..313576
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            313695..314657
                     /gene="cps2A"
                     /locus_tag="spr0314"
                     /db_xref="GeneID:934761"
     CDS             313695..314657
                     /gene="cps2A"
                     /locus_tag="spr0314"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357908.1"
                     /db_xref="GI:15902358"
                     /db_xref="GeneID:934761"
     gene            314551..315585
                     /gene="cps2H"
                     /locus_tag="spr0315"
                     /db_xref="GeneID:934766"
     CDS             314551..315585
                     /gene="cps2H"
                     /locus_tag="spr0315"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357909.1"
                     /db_xref="GI:15902359"
                     /db_xref="GeneID:934766"
     gene            315715..316872
                     /gene="cps2I"
                     /locus_tag="spr0316"
                     /db_xref="GeneID:934782"
     CDS             315715..316872
                     /gene="cps2I"
                     /locus_tag="spr0316"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357910.1"
                     /db_xref="GI:15902360"
                     /db_xref="GeneID:934782"
     gene            316869..318278
                     /gene="cps2J"
                     /locus_tag="spr0317"
                     /db_xref="GeneID:934770"
     CDS             316869..318278
                     /gene="cps2J"
                     /locus_tag="spr0317"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357911.1"
                     /db_xref="GI:15902361"
                     /db_xref="GeneID:934770"
     gene            318314..319552
                     /gene="cps2K"
                     /locus_tag="spr0318"
                     /db_xref="GeneID:934772"
     CDS             318314..319552
                     /gene="cps2K"
                     /locus_tag="spr0318"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357912.1"
                     /db_xref="GI:15902362"
                     /db_xref="GeneID:934772"
     gene            319581..320186
                     /gene="cps2P"
                     /locus_tag="spr0319"
                     /db_xref="GeneID:934780"
     CDS             319581..320186
                     /gene="cps2P"
                     /locus_tag="spr0319"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357913.1"
                     /db_xref="GI:15902363"
                     /db_xref="GeneID:934780"
     gene            320264..321133
                     /gene="cps2L"
                     /locus_tag="spr0320"
                     /db_xref="GeneID:934775"
     CDS             320264..321133
                     /gene="cps2L"
                     /locus_tag="spr0320"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357914.1"
                     /db_xref="GI:15902364"
                     /db_xref="GeneID:934775"
     gene            321134..321727
                     /gene="cps2M"
                     /locus_tag="spr0321"
                     /db_xref="GeneID:934787"
     CDS             321134..321727
                     /gene="cps2M"
                     /locus_tag="spr0321"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357915.1"
                     /db_xref="GI:15902365"
                     /db_xref="GeneID:934787"
     gene            321740..322789
                     /gene="cpsN"
                     /locus_tag="spr0322"
                     /db_xref="GeneID:934796"
     CDS             321740..322789
                     /gene="cpsN"
                     /locus_tag="spr0322"
                     /EC_number="4.2.1.46"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose-4,6-dehydratase"
                     /protein_id="NP_357916.1"
                     /db_xref="GI:15902366"
                     /db_xref="GeneID:934796"
     gene            322855..323706
                     /gene="cpsO"
                     /locus_tag="spr0323"
                     /db_xref="GeneID:934778"
     CDS             322855..323706
                     /gene="cpsO"
                     /locus_tag="spr0323"
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-L-rhamnose synthase"
                     /protein_id="NP_357917.1"
                     /db_xref="GI:15902367"
                     /db_xref="GeneID:934778"
     gene            324231..324680
                     /locus_tag="spr0325"
                     /db_xref="GeneID:934802"
     CDS             324231..324680
                     /locus_tag="spr0325"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357919.1"
                     /db_xref="GI:15902369"
                     /db_xref="GeneID:934802"
     gene            324751..324909
                     /locus_tag="spr0326"
                     /db_xref="GeneID:934785"
     CDS             324751..324909
                     /locus_tag="spr0326"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357920.1"
                     /db_xref="GI:15902370"
                     /db_xref="GeneID:934785"
     gene            325111..327093
                     /gene="aliA"
                     /locus_tag="spr0327"
                     /db_xref="GeneID:934786"
     CDS             325111..327093
                     /gene="aliA"
                     /locus_tag="spr0327"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_357921.1"
                     /db_xref="GI:15902371"
                     /db_xref="GeneID:934786"
     gene            327393..332696
                     /locus_tag="spr0328"
                     /db_xref="GeneID:934804"
     CDS             327393..332696
                     /locus_tag="spr0328"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor family protein"
                     /protein_id="NP_357922.1"
                     /db_xref="GI:15902372"
                     /db_xref="GeneID:934804"
     gene            complement(332863..335022)
                     /gene="pbpA"
                     /locus_tag="spr0329"
                     /db_xref="GeneID:934791"
     CDS             complement(332863..335022)
                     /gene="pbpA"
                     /locus_tag="spr0329"
                     /EC_number="2.3.2.-"
                     /EC_number="2.4.1.129"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1A"
                     /protein_id="NP_357923.1"
                     /db_xref="GI:15902373"
                     /db_xref="GeneID:934791"
     gene            complement(335019..335615)
                     /gene="recU"
                     /locus_tag="spr0330"
                     /db_xref="GeneID:934793"
     CDS             complement(335019..335615)
                     /gene="recU"
                     /locus_tag="spr0330"
                     /note="functions in homologous recombination, DNA repair,
                     and chromosome segregation; binds preferentially to three-
                     and four-stranded DNA intermediates; introduces specific
                     nick sites in four-stranded DNA substrates; functions
                     similarly to Escherichia coli RuvC"
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction-specific endonuclease"
                     /protein_id="NP_357924.1"
                     /db_xref="GI:15902374"
                     /db_xref="GeneID:934793"
     gene            335681..336208
                     /locus_tag="spr0331"
                     /db_xref="GeneID:934808"
     CDS             335681..336208
                     /locus_tag="spr0331"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357925.1"
                     /db_xref="GI:15902375"
                     /db_xref="GeneID:934808"
     gene            336266..336607
                     /locus_tag="spr0332"
                     /db_xref="GeneID:934797"
     CDS             336266..336607
                     /locus_tag="spr0332"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357926.1"
                     /db_xref="GI:15902376"
                     /db_xref="GeneID:934797"
     gene            336620..337023
                     /gene="rnpB"
                     /locus_tag="sprs02"
                     /db_xref="GeneID:934795"
     misc_RNA        336620..337023
                     /gene="rnpB"
                     /locus_tag="sprs02"
                     /product="Ribonuclease P - RNA component"
                     /db_xref="GeneID:934795"
     gene            337078..338250
                     /locus_tag="spr0333"
                     /db_xref="GeneID:934806"
     CDS             337078..338250
                     /locus_tag="spr0333"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357927.1"
                     /db_xref="GI:15902377"
                     /db_xref="GeneID:934806"
     gene            338263..339657
                     /locus_tag="spr0334"
                     /db_xref="GeneID:934807"
     CDS             338263..339657
                     /locus_tag="spr0334"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357928.1"
                     /db_xref="GI:15902378"
                     /db_xref="GeneID:934807"
     gene            339733..341157
                     /gene="gnd"
                     /locus_tag="spr0335"
                     /db_xref="GeneID:934817"
     CDS             339733..341157
                     /gene="gnd"
                     /locus_tag="spr0335"
                     /EC_number="1.1.1.44"
                     /note="catalyzes the formation of D-ribulose 5-phosphate
                     from 6-phospho-D-gluconate"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate dehydrogenase"
                     /protein_id="NP_357929.1"
                     /db_xref="GI:15902379"
                     /db_xref="GeneID:934817"
     gene            341169..341858
                     /gene="csrR"
                     /locus_tag="spr0336"
                     /db_xref="GeneID:934805"
     CDS             341169..341858
                     /gene="csrR"
                     /locus_tag="spr0336"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_357930.1"
                     /db_xref="GI:15902380"
                     /db_xref="GeneID:934805"
     gene            341956..342972
                     /gene="cbpF"
                     /locus_tag="spr0337"
                     /db_xref="GeneID:934810"
     CDS             341956..342972
                     /gene="cbpF"
                     /locus_tag="spr0337"
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein F"
                     /protein_id="NP_357931.1"
                     /db_xref="GI:15902381"
                     /db_xref="GeneID:934810"
     gene            343094..343972
                     /gene="mvk"
                     /locus_tag="spr0338"
                     /db_xref="GeneID:934821"
     CDS             343094..343972
                     /gene="mvk"
                     /locus_tag="spr0338"
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="NP_357932.1"
                     /db_xref="GI:15902382"
                     /db_xref="GeneID:934821"
     gene            343873..344907
                     /gene="mvd1"
                     /locus_tag="spr0339"
                     /db_xref="GeneID:934816"
     CDS             343873..344907
                     /gene="mvd1"
                     /locus_tag="spr0339"
                     /EC_number="4.1.1.33"
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="NP_357933.1"
                     /db_xref="GI:15902383"
                     /db_xref="GeneID:934816"
     gene            344894..345901
                     /gene="mvaK2"
                     /locus_tag="spr0340"
                     /db_xref="GeneID:934823"
     CDS             344894..345901
                     /gene="mvaK2"
                     /locus_tag="spr0340"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="NP_357934.1"
                     /db_xref="GI:15902384"
                     /db_xref="GeneID:934823"
     gene            345885..346895
                     /gene="fni"
                     /locus_tag="spr0341"
                     /db_xref="GeneID:934831"
     CDS             345885..346895
                     /gene="fni"
                     /locus_tag="spr0341"
                     /EC_number="5.3.3.2"
                     /note="catalyzes the isomerization of isopentenyl
                     pyrophosphate to dimethylallyl diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl pyrophosphate isomerase"
                     /protein_id="NP_357935.1"
                     /db_xref="GI:15902385"
                     /db_xref="GeneID:934831"
     gene            346973..347671
                     /locus_tag="spr0342"
                     /db_xref="GeneID:934819"
     CDS             346973..347671
                     /locus_tag="spr0342"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357936.1"
                     /db_xref="GI:15902386"
                     /db_xref="GeneID:934819"
     gene            347668..348663
                     /gene="hk03"
                     /locus_tag="spr0343"
                     /db_xref="GeneID:934820"
     CDS             347668..348663
                     /gene="hk03"
                     /locus_tag="spr0343"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="NP_357937.1"
                     /db_xref="GI:15902387"
                     /db_xref="GeneID:934820"
     gene            348677..349309
                     /gene="rr03"
                     /locus_tag="spr0344"
                     /db_xref="GeneID:934829"
     CDS             348677..349309
                     /gene="rr03"
                     /locus_tag="spr0344"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_357938.1"
                     /db_xref="GI:15902388"
                     /db_xref="GeneID:934829"
     repeat_region   349700..349816
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            350465..351374
                     /gene="cbpG-truncation"
                     /locus_tag="spr0349"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934734"
     gene            351393..352277
                     /gene="pcpC"
                     /locus_tag="spr0351"
                     /db_xref="GeneID:934801"
     CDS             351393..352277
                     /gene="pcpC"
                     /locus_tag="spr0351"
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="NP_357945.1"
                     /db_xref="GI:15902395"
                     /db_xref="GeneID:934801"
     gene            complement(352538..353113)
                     /gene="IS861-truncation"
                     /locus_tag="spr0352"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933907"
     gene            complement(353339..353608)
                     /locus_tag="spr0352a"
                     /db_xref="GeneID:19592986"
     CDS             complement(353339..353608)
                     /locus_tag="spr0352a"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="YP_008869150.1"
                     /db_xref="GI:651852201"
                     /db_xref="GeneID:19592986"
     gene            353760..355529
                     /gene="mtlA"
                     /locus_tag="spr0356"
                     /db_xref="GeneID:934701"
     CDS             353760..355529
                     /gene="mtlA"
                     /locus_tag="spr0356"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannitol-specific transporter subunit
                     IIBC"
                     /protein_id="NP_357950.1"
                     /db_xref="GI:15902400"
                     /db_xref="GeneID:934701"
     gene            355553..357508
                     /locus_tag="spr0357"
                     /db_xref="GeneID:934715"
     CDS             355553..357508
                     /locus_tag="spr0357"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_357951.1"
                     /db_xref="GI:15902401"
                     /db_xref="GeneID:934715"
     gene            357510..357947
                     /gene="mtlF"
                     /locus_tag="spr0358"
                     /db_xref="GeneID:932976"
     CDS             357510..357947
                     /gene="mtlF"
                     /locus_tag="spr0358"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannitol-specific transporter subunit
                     IIA"
                     /protein_id="NP_357952.1"
                     /db_xref="GI:15902402"
                     /db_xref="GeneID:932976"
     gene            358009..359145
                     /gene="mtlD"
                     /locus_tag="spr0359"
                     /db_xref="GeneID:933124"
     CDS             358009..359145
                     /gene="mtlD"
                     /locus_tag="spr0359"
                     /EC_number="1.1.1.17"
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="NP_357953.1"
                     /db_xref="GI:15902403"
                     /db_xref="GeneID:933124"
     repeat_region   359204..359289
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_bb"
     repeat_region   complement(359636..359742)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            359944..361227
                     /gene="tig"
                     /locus_tag="spr0362"
                     /db_xref="GeneID:933930"
     CDS             359944..361227
                     /gene="tig"
                     /locus_tag="spr0362"
                     /note="Tig; RopA; peptidyl-prolyl cis/trans isomerase;
                     promotes folding of newly synthesized proteins; binds
                     ribosomal 50S subunit; forms a homodimer"
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="NP_357956.1"
                     /db_xref="GI:15902406"
                     /db_xref="GeneID:933930"
     gene            complement(361275..363641)
                     /gene="recD"
                     /locus_tag="spr0363"
                     /db_xref="GeneID:934058"
     CDS             complement(361275..363641)
                     /gene="recD"
                     /locus_tag="spr0363"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease V"
                     /protein_id="NP_357957.1"
                     /db_xref="GI:15902407"
                     /db_xref="GeneID:934058"
     repeat_region   363689..363802
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(363875..364489)
                     /gene="spi"
                     /locus_tag="spr0364"
                     /db_xref="GeneID:934640"
     CDS             complement(363875..364489)
                     /gene="spi"
                     /locus_tag="spr0364"
                     /EC_number="3.4.21.89"
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="NP_357958.1"
                     /db_xref="GI:15902408"
                     /db_xref="GeneID:934640"
     gene            complement(364501..365373)
                     /gene="rnhB"
                     /locus_tag="spr0365"
                     /db_xref="GeneID:933085"
     CDS             complement(364501..365373)
                     /gene="rnhB"
                     /locus_tag="spr0365"
                     /EC_number="3.1.26.4"
                     /note="An endonuclease that specifically degrades the RNA
                     strand of RNA-DNA hybrids"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="NP_357959.1"
                     /db_xref="GI:15902409"
                     /db_xref="GeneID:933085"
     gene            365451..365762
                     /locus_tag="spr0366"
                     /db_xref="GeneID:934835"
     CDS             365451..365762
                     /locus_tag="spr0366"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357960.1"
                     /db_xref="GI:15902410"
                     /db_xref="GeneID:934835"
     gene            365759..366307
                     /locus_tag="spr0367"
                     /db_xref="GeneID:934646"
     CDS             365759..366307
                     /locus_tag="spr0367"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357961.1"
                     /db_xref="GI:15902411"
                     /db_xref="GeneID:934646"
     gene            366411..368747
                     /gene="mutS2"
                     /locus_tag="spr0368"
                     /db_xref="GeneID:934644"
     CDS             366411..368747
                     /gene="mutS2"
                     /locus_tag="spr0368"
                     /codon_start=1
                     /transl_table=11
                     /product="MutS2 family protein"
                     /protein_id="NP_357962.1"
                     /db_xref="GI:15902412"
                     /db_xref="GeneID:934644"
     gene            369089..370411
                     /gene="dagA"
                     /locus_tag="spr0369"
                     /db_xref="GeneID:934641"
     CDS             369089..370411
                     /gene="dagA"
                     /locus_tag="spr0369"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="NP_357963.1"
                     /db_xref="GI:15902413"
                     /db_xref="GeneID:934641"
     gene            370629..371177
                     /gene="mip"
                     /locus_tag="spr0370"
                     /db_xref="GeneID:934649"
     CDS             370629..371177
                     /gene="mip"
                     /locus_tag="spr0370"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357964.1"
                     /db_xref="GI:15902414"
                     /db_xref="GeneID:934649"
     gene            371275..372186
                     /gene="shetA"
                     /locus_tag="spr0371"
                     /db_xref="GeneID:934642"
     CDS             371275..372186
                     /gene="shetA"
                     /locus_tag="spr0371"
                     /codon_start=1
                     /transl_table=11
                     /product="exfoliative toxin"
                     /protein_id="NP_357965.1"
                     /db_xref="GI:15902415"
                     /db_xref="GeneID:934642"
     gene            complement(372211..373485)
                     /gene="serS"
                     /locus_tag="spr0372"
                     /db_xref="GeneID:934643"
     CDS             complement(372211..373485)
                     /gene="serS"
                     /locus_tag="spr0372"
                     /EC_number="6.1.1.11"
                     /note="catalyzes a two-step reaction, first charging a
                     serine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="seryl-tRNA synthetase"
                     /protein_id="NP_357966.2"
                     /db_xref="GI:161410754"
                     /db_xref="GeneID:934643"
     gene            complement(373698..374069)
                     /locus_tag="spr0373"
                     /db_xref="GeneID:934651"
     CDS             complement(373698..374069)
                     /locus_tag="spr0373"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357967.1"
                     /db_xref="GI:15902417"
                     /db_xref="GeneID:934651"
     gene            complement(374072..375436)
                     /gene="lysC"
                     /locus_tag="spr0374"
                     /db_xref="GeneID:934653"
     CDS             complement(374072..375436)
                     /gene="lysC"
                     /locus_tag="spr0374"
                     /EC_number="2.7.2.4"
                     /note="catalyzes the formation of 4-phospho-L-aspartate
                     from L-aspartate and ATP; lysine and threonine sensitive"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="NP_357968.1"
                     /db_xref="GI:15902418"
                     /db_xref="GeneID:934653"
     repeat_region   complement(375619..375730)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            375761..376546
                     /gene="phaB"
                     /locus_tag="spr0375"
                     /db_xref="GeneID:934663"
     CDS             375761..376546
                     /gene="phaB"
                     /locus_tag="spr0375"
                     /EC_number="4.2.1.17"
                     /note="Catalyzes the reversible hydration of unsaturated
                     fatty acyl-CoA to beta-hydroxyacyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="NP_357969.1"
                     /db_xref="GI:15902419"
                     /db_xref="GeneID:934663"
     gene            376640..377074
                     /locus_tag="spr0376"
                     /db_xref="GeneID:934658"
     CDS             376640..377074
                     /locus_tag="spr0376"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357970.1"
                     /db_xref="GI:15902420"
                     /db_xref="GeneID:934658"
     gene            377074..378048
                     /gene="fabH"
                     /locus_tag="spr0377"
                     /db_xref="GeneID:934655"
     CDS             377074..378048
                     /gene="fabH"
                     /locus_tag="spr0377"
                     /EC_number="2.3.1.41"
                     /note="FabH; beta-ketoacyl-acyl carrier protein synthase
                     III; catalyzes the condensation of acetyl-CoA with
                     malonyl-ACP to initiate cycles of fatty acid elongation;
                     differs from 3-oxoacyl-(acyl carrier protein) synthase I
                     and II in that it utilizes CoA thioesters as primers
                     rather than acyl-ACPs"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP synthase"
                     /protein_id="NP_357971.1"
                     /db_xref="GI:15902421"
                     /db_xref="GeneID:934655"
     gene            378108..378332
                     /gene="acpP"
                     /locus_tag="spr0378"
                     /db_xref="GeneID:934673"
     CDS             378108..378332
                     /gene="acpP"
                     /locus_tag="spr0378"
                     /note="carries the fatty acid chain in fatty acid
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="NP_357972.1"
                     /db_xref="GI:15902422"
                     /db_xref="GeneID:934673"
     gene            378451..379425
                     /gene="fabK"
                     /locus_tag="spr0379"
                     /db_xref="GeneID:934670"
     CDS             378451..379425
                     /gene="fabK"
                     /locus_tag="spr0379"
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-acyl carrier protein(ACP) reductase"
                     /protein_id="NP_357973.1"
                     /db_xref="GI:15902423"
                     /db_xref="GeneID:934670"
     gene            379418..380338
                     /gene="fabD"
                     /locus_tag="spr0380"
                     /db_xref="GeneID:934657"
     CDS             379418..380338
                     /gene="fabD"
                     /locus_tag="spr0380"
                     /EC_number="2.3.1.39"
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="NP_357974.1"
                     /db_xref="GI:15902424"
                     /db_xref="GeneID:934657"
     gene            380372..381103
                     /gene="fabG"
                     /locus_tag="spr0381"
                     /db_xref="GeneID:934672"
     CDS             380372..381103
                     /gene="fabG"
                     /locus_tag="spr0381"
                     /EC_number="1.1.1.100"
                     /note="catalyzes the first of the two reduction steps in
                     the elongation cycle of fatty acid synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="NP_357975.1"
                     /db_xref="GI:15902425"
                     /db_xref="GeneID:934672"
     gene            381116..382360
                     /gene="fabF"
                     /locus_tag="spr0382"
                     /db_xref="GeneID:934660"
     CDS             381116..382360
                     /gene="fabF"
                     /locus_tag="spr0382"
                     /EC_number="2.3.1.41"
                     /note="FabF; beta-ketoacyl-ACP synthase II, KASII;
                     catalyzes a condensation reaction in fatty acid
                     biosynthesis: addition of an acyl acceptor of two carbons
                     from malonyl-ACP; required for the elongation of
                     short-chain unsaturated acyl-ACP"
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP synthase"
                     /protein_id="NP_357976.1"
                     /db_xref="GI:15902426"
                     /db_xref="GeneID:934660"
     gene            382363..382848
                     /gene="accB"
                     /locus_tag="spr0383"
                     /db_xref="GeneID:934665"
     CDS             382363..382848
                     /gene="accB"
                     /locus_tag="spr0383"
                     /EC_number="6.4.1.2"
                     /note="composes the biotin carboxyl carrier protein
                     subunit of the acetyl-CoA carboxylase complex, the enzyme
                     that catalyzes the carboxylation of acetyl-CoA to
                     malonyl-CoA, which in turn controls the rate of fatty acid
                     metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="NP_357977.1"
                     /db_xref="GI:15902427"
                     /db_xref="GeneID:934665"
     gene            382845..383267
                     /gene="fabZ"
                     /locus_tag="spr0384"
                     /db_xref="GeneID:934674"
     CDS             382845..383267
                     /gene="fabZ"
                     /locus_tag="spr0384"
                     /EC_number="4.2.1.-"
                     /note="in Pseudomonas aeruginosa this enzyme is a trimer
                     of dimers; essential for membrane formation; performs
                     third step of type II fatty acid biosynthesis; catalyzes
                     dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP"
                     /codon_start=1
                     /transl_table=11
                     /product="(3R)-hydroxymyristoyl-ACP dehydratase"
                     /protein_id="NP_357978.1"
                     /db_xref="GI:15902428"
                     /db_xref="GeneID:934674"
     gene            383279..384646
                     /gene="accC"
                     /locus_tag="spr0385"
                     /db_xref="GeneID:934681"
     CDS             383279..384646
                     /gene="accC"
                     /locus_tag="spr0385"
                     /EC_number="6.4.1.2"
                     /note="an AccC homodimer forms the biotin carboxylase
                     subunit of the acetyl CoA carboxylase, an enzyme that
                     catalyzes the formation of malonyl-CoA, which in turn
                     controls the rate of fatty acid metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="NP_357979.1"
                     /db_xref="GI:15902429"
                     /db_xref="GeneID:934681"
     gene            384683..385549
                     /gene="accD"
                     /locus_tag="spr0386"
                     /db_xref="GeneID:934669"
     CDS             384683..385549
                     /gene="accD"
                     /locus_tag="spr0386"
                     /EC_number="6.4.1.2"
                     /note="catalyzes the carboxylation of acetyl-CoA to
                     malonyl-CoA; forms a tetramer of AccA2D2 subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase subunit beta"
                     /protein_id="NP_357980.1"
                     /db_xref="GI:15902430"
                     /db_xref="GeneID:934669"
     gene            385546..386313
                     /gene="accA"
                     /locus_tag="spr0387"
                     /db_xref="GeneID:934683"
     CDS             385546..386313
                     /gene="accA"
                     /locus_tag="spr0387"
                     /EC_number="6.4.1.2"
                     /note="catalyzes the carboxylation of acetyl-CoA to
                     malonyl-CoA; forms a tetramer composed of two alpha (AccA)
                     and two beta (AccD) subunits; one of the two catalytic
                     subunits that can form the acetyl CoA carboxylase enzyme
                     together with a carrier protein; these proteins present a
                     shorter N-terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase subunit alpha"
                     /protein_id="NP_357981.1"
                     /db_xref="GI:15902431"
                     /db_xref="GeneID:934683"
     gene            386472..386657
                     /locus_tag="spr0388"
                     /db_xref="GeneID:934671"
     CDS             386472..386657
                     /locus_tag="spr0388"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008869151.1"
                     /db_xref="GI:651852202"
                     /db_xref="GeneID:934671"
     gene            complement(387424..387864)
                     /gene="nusB"
                     /locus_tag="spr0390"
                     /db_xref="GeneID:934688"
     CDS             complement(387424..387864)
                     /gene="nusB"
                     /locus_tag="spr0390"
                     /note="Regulates rRNA biosynthesis by transcriptional
                     antitermination"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination protein NusB"
                     /protein_id="NP_357984.1"
                     /db_xref="GI:15902434"
                     /db_xref="GeneID:934688"
     gene            complement(387839..388228)
                     /locus_tag="spr0391"
                     /db_xref="GeneID:934678"
     CDS             complement(387839..388228)
                     /locus_tag="spr0391"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357985.1"
                     /db_xref="GI:15902435"
                     /db_xref="GeneID:934678"
     gene            complement(388250..388810)
                     /gene="efp"
                     /locus_tag="spr0392"
                     /db_xref="GeneID:934680"
     CDS             complement(388250..388810)
                     /gene="efp"
                     /locus_tag="spr0392"
                     /note="Involved in peptide bond synthesis; alters the
                     affinity of the ribosome for aminoacyl-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="NP_357986.1"
                     /db_xref="GI:15902436"
                     /db_xref="GeneID:934680"
     gene            complement(388939..390381)
                     /gene="gatB"
                     /locus_tag="spr0393"
                     /db_xref="GeneID:934697"
     CDS             complement(388939..390381)
                     /gene="gatB"
                     /locus_tag="spr0393"
                     /note="allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms
                     which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases; reaction takes place in the
                     presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA amidotransferase subunit
                     B"
                     /protein_id="NP_357987.1"
                     /db_xref="GI:15902437"
                     /db_xref="GeneID:934697"
     gene            complement(390381..391847)
                     /gene="gatA"
                     /locus_tag="spr0394"
                     /db_xref="GeneID:934695"
     CDS             complement(390381..391847)
                     /gene="gatA"
                     /locus_tag="spr0394"
                     /note="allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms
                     which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases; reaction takes place in the
                     presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA amidotransferase subunit
                     A"
                     /protein_id="NP_357988.1"
                     /db_xref="GI:15902438"
                     /db_xref="GeneID:934695"
     gene            complement(391847..392149)
                     /gene="gatC"
                     /locus_tag="spr0395"
                     /db_xref="GeneID:934685"
     CDS             complement(391847..392149)
                     /gene="gatC"
                     /locus_tag="spr0395"
                     /note="allows the formation of correctly charged
                     Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation
                     of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms
                     which lack either or both of asparaginyl-tRNA or
                     glutaminyl-tRNA synthetases; reaction takes place in the
                     presence of glutamine and ATP through an activated
                     phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; some Mycoplasma
                     proteins contain an N-terminal fusion to an unknown
                     domain"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl/glutamyl-tRNA amidotransferase subunit
                     C"
                     /protein_id="NP_357989.1"
                     /db_xref="GI:15902439"
                     /db_xref="GeneID:934685"
     gene            392362..393906
                     /gene="prfC"
                     /locus_tag="spr0396"
                     /db_xref="GeneID:934704"
     CDS             392362..393906
                     /gene="prfC"
                     /locus_tag="spr0396"
                     /note="stimulates the release of release factors 1 and 2
                     from the ribosome after hydrolysis of the ester bond in
                     peptidyl-tRNA has occurred; GDP/GTP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="NP_357990.1"
                     /db_xref="GI:15902440"
                     /db_xref="GeneID:934704"
     gene            394175..394660
                     /locus_tag="spr0397"
                     /db_xref="GeneID:934691"
     CDS             394175..394660
                     /locus_tag="spr0397"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357991.1"
                     /db_xref="GI:15902441"
                     /db_xref="GeneID:934691"
     gene            394776..394964
                     /gene="rpmB"
                     /locus_tag="spr0398"
                     /db_xref="GeneID:934689"
     CDS             394776..394964
                     /gene="rpmB"
                     /locus_tag="spr0398"
                     /note="required for 70S ribosome assembly"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="NP_357992.1"
                     /db_xref="GI:15902442"
                     /db_xref="GeneID:934689"
     gene            395121..395486
                     /gene="asp23"
                     /locus_tag="spr0399"
                     /db_xref="GeneID:934702"
     CDS             395121..395486
                     /gene="asp23"
                     /locus_tag="spr0399"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357993.1"
                     /db_xref="GI:15902443"
                     /db_xref="GeneID:934702"
     gene            395489..397156
                     /locus_tag="spr0400"
                     /db_xref="GeneID:934693"
     CDS             395489..397156
                     /locus_tag="spr0400"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357994.1"
                     /db_xref="GI:15902444"
                     /db_xref="GeneID:934693"
     gene            397357..399057
                     /gene="ilvB"
                     /locus_tag="spr0401"
                     /db_xref="GeneID:934698"
     CDS             397357..399057
                     /gene="ilvB"
                     /locus_tag="spr0401"
                     /EC_number="2.2.1.6"
                     /note="catalyzes the formation of 2-acetolactate from
                     pyruvate; also known as acetolactate synthase large
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase catalytic subunit"
                     /protein_id="NP_357995.1"
                     /db_xref="GI:15902445"
                     /db_xref="GeneID:934698"
     gene            399026..399526
                     /gene="ilvH"
                     /locus_tag="spr0402"
                     /db_xref="GeneID:934725"
     CDS             399026..399526
                     /gene="ilvH"
                     /locus_tag="spr0402"
                     /EC_number="2.2.1.6"
                     /note="with IlvI catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase 3 small
                     subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 regulatory subunit"
                     /protein_id="NP_357996.1"
                     /db_xref="GI:15902446"
                     /db_xref="GeneID:934725"
     gene            399592..400614
                     /gene="ilvC"
                     /locus_tag="spr0403"
                     /db_xref="GeneID:934707"
     CDS             399592..400614
                     /gene="ilvC"
                     /locus_tag="spr0403"
                     /EC_number="1.1.1.86"
                     /note="catalyzes the formation of
                     (R)-2,3-dihydroxy-3-methylbutanoate from
                     (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and
                     isoleucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="NP_357997.1"
                     /db_xref="GI:15902447"
                     /db_xref="GeneID:934707"
     gene            400691..401181
                     /locus_tag="spr0404"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934699"
     gene            401195..401551
                     /locus_tag="spr0405"
                     /db_xref="GeneID:934721"
     CDS             401195..401551
                     /locus_tag="spr0405"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_357999.1"
                     /db_xref="GI:15902449"
                     /db_xref="GeneID:934721"
     gene            401601..402851
                     /gene="ilvA"
                     /locus_tag="spr0406"
                     /db_xref="GeneID:934708"
     CDS             401601..402851
                     /gene="ilvA"
                     /locus_tag="spr0406"
                     /EC_number="4.3.1.19"
                     /note="catalyzes the formation of 2-oxobutanoate from
                     L-threonine; biosynthetic"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine dehydratase"
                     /protein_id="NP_358000.1"
                     /db_xref="GI:15902450"
                     /db_xref="GeneID:934708"
     repeat_region   402922..403038
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            403586..403801
                     /locus_tag="spr0407"
                     /db_xref="GeneID:934719"
     CDS             403586..403801
                     /locus_tag="spr0407"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358001.1"
                     /db_xref="GI:15902451"
                     /db_xref="GeneID:934719"
     gene            complement(403910..404650)
                     /gene="glnQ"
                     /locus_tag="spr0408"
                     /db_xref="GeneID:934709"
     CDS             complement(403910..404650)
                     /gene="glnQ"
                     /locus_tag="spr0408"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358002.1"
                     /db_xref="GI:15902452"
                     /db_xref="GeneID:934709"
     gene            complement(404650..406215)
                     /gene="glnH"
                     /locus_tag="spr0409"
                     /db_xref="GeneID:934710"
     CDS             complement(404650..406215)
                     /gene="glnH"
                     /locus_tag="spr0409"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358003.2"
                     /db_xref="GI:555247341"
                     /db_xref="GeneID:934710"
     gene            406350..408242
                     /locus_tag="spr0410"
                     /db_xref="GeneID:934724"
     CDS             406350..408242
                     /locus_tag="spr0410"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358004.1"
                     /db_xref="GI:15902454"
                     /db_xref="GeneID:934724"
     gene            complement(408542..409410)
                     /gene="transposase_F"
                     /locus_tag="spr0412"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934714"
     gene            409666..410511
                     /gene="uppP"
                     /locus_tag="spr0413"
                     /db_xref="GeneID:934740"
     CDS             409666..410511
                     /gene="uppP"
                     /locus_tag="spr0413"
                     /EC_number="3.6.1.27"
                     /note="BacA; phosphatase activity in Escherichia coli not
                     kinase; involved in bacitracin resistance as bacitracin
                     supposedly sequesters undecaprenyl disphosphate which
                     reduces the pool of lipid carrier available to the cell"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl pyrophosphate phosphatase"
                     /protein_id="NP_358007.1"
                     /db_xref="GI:15902457"
                     /db_xref="GeneID:934740"
     repeat_region   410546..410654
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(410657..411727)
                     /gene="dinP"
                     /locus_tag="spr0414"
                     /db_xref="GeneID:934718"
     CDS             complement(410657..411727)
                     /gene="dinP"
                     /locus_tag="spr0414"
                     /EC_number="2.7.7.7"
                     /note="involved in translesion DNA polymerization with
                     beta clamp of polymerase III; belongs to Y family of
                     polymerases; does not contain proofreading function"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="NP_358008.1"
                     /db_xref="GI:15902458"
                     /db_xref="GeneID:934718"
     repeat_region   411734..411890
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            412113..414437
                     /gene="pfl"
                     /locus_tag="spr0415"
                     /db_xref="GeneID:934727"
     CDS             412113..414437
                     /gene="pfl"
                     /locus_tag="spr0415"
                     /EC_number="2.3.1.54"
                     /codon_start=1
                     /transl_table=11
                     /product="formate acetyltransferase"
                     /protein_id="NP_358009.1"
                     /db_xref="GI:15902459"
                     /db_xref="GeneID:934727"
     repeat_region   414568..414674
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(415349..415633)
                     /locus_tag="spr0417"
                     /db_xref="GeneID:934731"
     CDS             complement(415349..415633)
                     /locus_tag="spr0417"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358011.1"
                     /db_xref="GI:15902461"
                     /db_xref="GeneID:934731"
     gene            complement(417068..418291)
                     /gene="xylR"
                     /locus_tag="spr0420"
                     /db_xref="GeneID:934739"
     CDS             complement(417068..418291)
                     /gene="xylR"
                     /locus_tag="spr0420"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="NP_358014.1"
                     /db_xref="GI:15902464"
                     /db_xref="GeneID:934739"
     gene            418456..419781
                     /gene="PTS-EII"
                     /locus_tag="spr0421"
                     /db_xref="GeneID:934738"
     CDS             418456..419781
                     /gene="PTS-EII"
                     /locus_tag="spr0421"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system cellobiose-specific transporter
                     subunit IIC"
                     /protein_id="NP_358015.1"
                     /db_xref="GI:15902465"
                     /db_xref="GeneID:934738"
     gene            419729..421669
                     /locus_tag="spr0422"
                     /db_xref="GeneID:934749"
     CDS             419729..421669
                     /locus_tag="spr0422"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358016.1"
                     /db_xref="GI:15902466"
                     /db_xref="GeneID:934749"
     gene            421837..422181
                     /gene="PTS-EII"
                     /locus_tag="spr0423"
                     /db_xref="GeneID:934748"
     CDS             421837..422181
                     /gene="PTS-EII"
                     /locus_tag="spr0423"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system lactose-specific transporter subunit
                     IIA"
                     /protein_id="NP_358017.1"
                     /db_xref="GI:15902467"
                     /db_xref="GeneID:934748"
     gene            422191..423603
                     /gene="lacG"
                     /locus_tag="spr0424"
                     /db_xref="GeneID:934741"
     CDS             422191..423603
                     /gene="lacG"
                     /locus_tag="spr0424"
                     /EC_number="3.2.1.85"
                     /note="catalyzes the formation of 6-phospho-galactose from
                     a 6-phospho-beta-galactoside"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="NP_358018.1"
                     /db_xref="GI:15902468"
                     /db_xref="GeneID:934741"
     gene            423672..425351
                     /gene="PTS-EII"
                     /locus_tag="spr0425"
                     /db_xref="GeneID:934754"
     CDS             423672..425351
                     /gene="PTS-EII"
                     /locus_tag="spr0425"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system sugar-specific transporter subunit
                     EII"
                     /protein_id="NP_358019.1"
                     /db_xref="GI:15902469"
                     /db_xref="GeneID:934754"
     gene            complement(425479..426918)
                     /gene="trkH"
                     /locus_tag="spr0426"
                     /db_xref="GeneID:934745"
     CDS             complement(425479..426918)
                     /gene="trkH"
                     /locus_tag="spr0426"
                     /codon_start=1
                     /transl_table=11
                     /product="Trk transporter membrane-spanning protein"
                     /protein_id="NP_358020.1"
                     /db_xref="GI:15902470"
                     /db_xref="GeneID:934745"
     gene            complement(426922..428271)
                     /gene="trkA"
                     /locus_tag="spr0427"
                     /gene_synonym="sapG"
                     /db_xref="GeneID:934746"
     CDS             complement(426922..428271)
                     /gene="trkA"
                     /locus_tag="spr0427"
                     /gene_synonym="sapG"
                     /note="involved in potassium uptake; found to be
                     peripherally associated with the inner membrane in
                     Escherichia coli; contains an NAD-binding domain"
                     /codon_start=1
                     /transl_table=11
                     /product="potassium transporter peripheral membrane
                     component"
                     /protein_id="NP_358021.1"
                     /db_xref="GI:15902471"
                     /db_xref="GeneID:934746"
     gene            428433..429308
                     /locus_tag="spr0428"
                     /db_xref="GeneID:934755"
     CDS             428433..429308
                     /locus_tag="spr0428"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358022.1"
                     /db_xref="GI:15902472"
                     /db_xref="GeneID:934755"
     gene            429323..429871
                     /locus_tag="spr0429"
                     /db_xref="GeneID:934767"
     CDS             429323..429871
                     /locus_tag="spr0429"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358023.1"
                     /db_xref="GI:15902473"
                     /db_xref="GeneID:934767"
     repeat_region   complement(429871..430021)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            429878..430090
                     /locus_tag="spr0429a"
                     /db_xref="GeneID:19592987"
     CDS             429878..430090
                     /locus_tag="spr0429a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008869152.1"
                     /db_xref="GI:651852203"
                     /db_xref="GeneID:19592987"
     gene            430192..431874
                     /gene="ABC-NBD"
                     /locus_tag="spr0430"
                     /db_xref="GeneID:934771"
     CDS             430192..431874
                     /gene="ABC-NBD"
                     /locus_tag="spr0430"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358024.1"
                     /db_xref="GI:15902474"
                     /db_xref="GeneID:934771"
     gene            431859..432689
                     /gene="ABC-MSD"
                     /locus_tag="spr0431"
                     /db_xref="GeneID:934760"
     CDS             431859..432689
                     /gene="ABC-MSD"
                     /locus_tag="spr0431"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358025.1"
                     /db_xref="GI:15902475"
                     /db_xref="GeneID:934760"
     gene            432843..433385
                     /gene="cspR"
                     /locus_tag="spr0432"
                     /db_xref="GeneID:934758"
     CDS             432843..433385
                     /gene="cspR"
                     /locus_tag="spr0432"
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA methylase"
                     /protein_id="NP_358026.1"
                     /db_xref="GI:15902476"
                     /db_xref="GeneID:934758"
     gene            433829..434407
                     /locus_tag="spr0433"
                     /db_xref="GeneID:934779"
     CDS             433829..434407
                     /locus_tag="spr0433"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358027.1"
                     /db_xref="GI:15902477"
                     /db_xref="GeneID:934779"
     gene            434397..435047
                     /locus_tag="spr0434"
                     /db_xref="GeneID:934762"
     CDS             434397..435047
                     /locus_tag="spr0434"
                     /note="Probable phosphatidic acid phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="NP_358028.1"
                     /db_xref="GI:15902478"
                     /db_xref="GeneID:934762"
     gene            435075..435464
                     /locus_tag="spr0435"
                     /db_xref="GeneID:934768"
     CDS             435075..435464
                     /locus_tag="spr0435"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358029.1"
                     /db_xref="GI:15902479"
                     /db_xref="GeneID:934768"
     gene            435469..435918
                     /locus_tag="spr0436"
                     /db_xref="GeneID:934769"
     CDS             435469..435918
                     /locus_tag="spr0436"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358030.1"
                     /db_xref="GI:15902480"
                     /db_xref="GeneID:934769"
     gene            436046..436633
                     /gene="rpoE"
                     /locus_tag="spr0437"
                     /db_xref="GeneID:934765"
     CDS             436046..436633
                     /gene="rpoE"
                     /locus_tag="spr0437"
                     /note="participates in both the initiation and recycling
                     phases of transcription; in the presence of the delta
                     subunit, RNAP displays an increased specificity of
                     transcription, a decreased affinity for nucleic acids, and
                     an increased efficiency of RNA synthesis because of
                     enhanced recycling"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="NP_358031.2"
                     /db_xref="GI:161410753"
                     /db_xref="GeneID:934765"
     repeat_region   complement(436760..436915)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            437023..438630
                     /gene="pyrG"
                     /locus_tag="spr0438"
                     /db_xref="GeneID:934794"
     CDS             437023..438630
                     /gene="pyrG"
                     /locus_tag="spr0438"
                     /EC_number="6.3.4.2"
                     /note="CTP synthase; CTP synthase; cytidine triphosphate
                     synthetase; catalyzes the ATP-dependent amination of UTP
                     to CTP with either L-glutamine or ammonia as the source of
                     nitrogen; in Escherichia coli this enzyme forms a
                     homotetramer"
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthetase"
                     /protein_id="NP_358032.1"
                     /db_xref="GI:15902482"
                     /db_xref="GeneID:934794"
     repeat_region   complement(438871..438969)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     repeat_region   complement(438989..439087)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(439189..440820)
                     /locus_tag="spr0439"
                     /db_xref="GeneID:934792"
     CDS             complement(439189..440820)
                     /locus_tag="spr0439"
                     /note="Probable integral membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358033.1"
                     /db_xref="GI:15902483"
                     /db_xref="GeneID:934792"
     gene            441113..446092
                     /locus_tag="spr0440"
                     /db_xref="GeneID:934776"
     CDS             441113..446092
                     /locus_tag="spr0440"
                     /note="Similar to endo-beta-N-acetylglucosaminidase"
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="NP_358034.1"
                     /db_xref="GI:15902484"
                     /db_xref="GeneID:934776"
     gene            446182..447378
                     /gene="pgk"
                     /locus_tag="spr0441"
                     /db_xref="GeneID:934773"
     CDS             446182..447378
                     /gene="pgk"
                     /locus_tag="spr0441"
                     /EC_number="2.7.2.3"
                     /note="Converts 3-phospho-D-glycerate to
                     3-phospho-D-glyceroyl phosphate during the glycolysis
                     pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="NP_358035.1"
                     /db_xref="GI:15902485"
                     /db_xref="GeneID:934773"
     gene            447514..448041
                     /locus_tag="spr0442"
                     /db_xref="GeneID:934790"
     CDS             447514..448041
                     /locus_tag="spr0442"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358036.1"
                     /db_xref="GI:15902486"
                     /db_xref="GeneID:934790"
     gene            448118..448474
                     /gene="glnR"
                     /locus_tag="spr0443"
                     /db_xref="GeneID:934781"
     CDS             448118..448474
                     /gene="glnR"
                     /locus_tag="spr0443"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor of the glutamine
                     synthetase gene"
                     /protein_id="NP_358037.1"
                     /db_xref="GI:15902487"
                     /db_xref="GeneID:934781"
     gene            448511..449857
                     /gene="glnA"
                     /locus_tag="spr0444"
                     /db_xref="GeneID:934783"
     CDS             448511..449857
                     /gene="glnA"
                     /locus_tag="spr0444"
                     /EC_number="6.3.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase, type I"
                     /protein_id="NP_358038.1"
                     /db_xref="GI:15902488"
                     /db_xref="GeneID:934783"
     repeat_region   450208..450279
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            450637..451917
                     /gene="hsdS"
                     /locus_tag="spr0445"
                     /db_xref="GeneID:934784"
     CDS             450637..451917
                     /gene="hsdS"
                     /locus_tag="spr0445"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system S
                     subunit"
                     /protein_id="NP_358039.1"
                     /db_xref="GI:15902489"
                     /db_xref="GeneID:934784"
     gene            complement(451871..452470)
                     /gene="hsdS"
                     /locus_tag="spr0446"
                     /db_xref="GeneID:934789"
     CDS             complement(451871..452470)
                     /gene="hsdS"
                     /locus_tag="spr0446"
                     /EC_number="3.1.21.3"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system S
                     subunit"
                     /protein_id="NP_358040.1"
                     /db_xref="GI:15902490"
                     /db_xref="GeneID:934789"
     gene            complement(452481..453278)
                     /gene="xerD"
                     /locus_tag="spr0447"
                     /db_xref="GeneID:934813"
     CDS             complement(452481..453278)
                     /gene="xerD"
                     /locus_tag="spr0447"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase/recombinase"
                     /protein_id="NP_358041.1"
                     /db_xref="GI:15902491"
                     /db_xref="GeneID:934813"
     gene            complement(453335..454903)
                     /gene="hsdS"
                     /locus_tag="spr0448"
                     /db_xref="GeneID:934798"
     CDS             complement(453335..454903)
                     /gene="hsdS"
                     /locus_tag="spr0448"
                     /EC_number="3.1.21.3"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system S
                     subunit"
                     /protein_id="NP_358042.1"
                     /db_xref="GI:15902492"
                     /db_xref="GeneID:934798"
     gene            complement(454903..456366)
                     /gene="hsdM"
                     /locus_tag="spr0449"
                     /db_xref="GeneID:934799"
     CDS             complement(454903..456366)
                     /gene="hsdM"
                     /locus_tag="spr0449"
                     /EC_number="3.1.21.3"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system M
                     subunit"
                     /protein_id="NP_358043.1"
                     /db_xref="GI:15902493"
                     /db_xref="GeneID:934799"
     gene            complement(456379..458712)
                     /gene="hsdR"
                     /locus_tag="spr0450"
                     /db_xref="GeneID:934824"
     CDS             complement(456379..458712)
                     /gene="hsdR"
                     /locus_tag="spr0450"
                     /EC_number="3.1.21.3"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system R
                     subunit"
                     /protein_id="NP_358044.1"
                     /db_xref="GI:15902494"
                     /db_xref="REBASE:SpnRORF449P"
                     /db_xref="GeneID:934824"
     gene            459085..459285
                     /locus_tag="spr0451"
                     /db_xref="GeneID:934800"
     CDS             459085..459285
                     /locus_tag="spr0451"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358045.1"
                     /db_xref="GI:15902495"
                     /db_xref="GeneID:934800"
     gene            459320..459829
                     /locus_tag="spr0452"
                     /db_xref="GeneID:934803"
     CDS             459320..459829
                     /locus_tag="spr0452"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358046.1"
                     /db_xref="GI:15902496"
                     /db_xref="GeneID:934803"
     gene            459960..461027
                     /gene="hrcA"
                     /locus_tag="spr0453"
                     /db_xref="GeneID:934815"
     CDS             459960..461027
                     /gene="hrcA"
                     /locus_tag="spr0453"
                     /note="Negative regulator of class I heat shock genes
                     (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock
                     induction of these operons"
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcription repressor"
                     /protein_id="NP_358047.1"
                     /db_xref="GI:15902497"
                     /db_xref="GeneID:934815"
     gene            461030..461578
                     /gene="grpE"
                     /locus_tag="spr0454"
                     /db_xref="GeneID:934809"
     CDS             461030..461578
                     /gene="grpE"
                     /locus_tag="spr0454"
                     /note="with DnaK and DnaJ acts in response to hyperosmotic
                     and heat shock by preventing the aggregation of
                     stress-denatured proteins; may act as a thermosensor"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein GrpE"
                     /protein_id="NP_358048.1"
                     /db_xref="GI:15902498"
                     /db_xref="GeneID:934809"
     gene            462058..463881
                     /gene="dnaK"
                     /locus_tag="spr0455"
                     /db_xref="GeneID:934811"
     CDS             462058..463881
                     /gene="dnaK"
                     /locus_tag="spr0455"
                     /note="heat shock protein 70; assists in folding of
                     nascent polypeptide chains; refolding of misfolded
                     proteins; utilizes ATPase activity to help fold;
                     co-chaperones are DnaJ and GrpE; multiple copies in some
                     bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="NP_358049.1"
                     /db_xref="GI:15902499"
                     /db_xref="GeneID:934811"
     gene            464641..465759
                     /gene="dnaJ"
                     /locus_tag="spr0456"
                     /db_xref="GeneID:934826"
     CDS             464641..465759
                     /gene="dnaJ"
                     /locus_tag="spr0456"
                     /note="chaperone Hsp40; co-chaperone with DnaK;
                     Participates actively in the response to hyperosmotic and
                     heat shock by preventing the aggregation of
                     stress-denatured proteins and by disaggregating proteins,
                     also in an autonomous, dnaK-independent fashion"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="NP_358050.1"
                     /db_xref="GI:15902500"
                     /db_xref="GeneID:934826"
     repeat_region   465817..465861
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            complement(466094..466381)
                     /locus_tag="spr0457"
                     /db_xref="GeneID:934812"
     CDS             complement(466094..466381)
                     /locus_tag="spr0457"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358051.1"
                     /db_xref="GI:15902501"
                     /db_xref="GeneID:934812"
     gene            complement(466391..466801)
                     /locus_tag="spr0458"
                     /db_xref="GeneID:934830"
     CDS             complement(466391..466801)
                     /locus_tag="spr0458"
                     /note="HIT-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358052.1"
                     /db_xref="GI:15902502"
                     /db_xref="GeneID:934830"
     gene            466869..467600
                     /gene="ABC-NBD"
                     /locus_tag="spr0459"
                     /db_xref="GeneID:934822"
     CDS             466869..467600
                     /gene="ABC-NBD"
                     /locus_tag="spr0459"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358053.1"
                     /db_xref="GI:15902503"
                     /db_xref="GeneID:934822"
     gene            467597..468646
                     /gene="ABC-MSP"
                     /locus_tag="spr0460"
                     /db_xref="GeneID:934832"
     CDS             467597..468646
                     /gene="ABC-MSP"
                     /locus_tag="spr0460"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_358054.1"
                     /db_xref="GI:15902504"
                     /db_xref="GeneID:934832"
     repeat_region   468740..468843
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     gene            complement(468814..469143)
                     /gene="blpT"
                     /locus_tag="spr0461"
                     /db_xref="GeneID:934827"
     CDS             complement(468814..469143)
                     /gene="blpT"
                     /locus_tag="spr0461"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358055.1"
                     /db_xref="GI:15902505"
                     /db_xref="GeneID:934827"
     gene            469419..469757
                     /gene="blpS"
                     /locus_tag="spr0462"
                     /db_xref="GeneID:934833"
     CDS             469419..469757
                     /gene="blpS"
                     /locus_tag="spr0462"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein BlpS"
                     /protein_id="NP_358056.1"
                     /db_xref="GI:15902506"
                     /db_xref="GeneID:934833"
     gene            469762..470499
                     /gene="rr13"
                     /locus_tag="spr0463"
                     /db_xref="GeneID:933176"
     CDS             469762..470499
                     /gene="rr13"
                     /locus_tag="spr0463"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator BlpR"
                     /protein_id="NP_358057.1"
                     /db_xref="GI:15902507"
                     /db_xref="GeneID:933176"
     gene            470513..471853
                     /gene="hk13"
                     /locus_tag="spr0464"
                     /db_xref="GeneID:933263"
     CDS             470513..471853
                     /gene="hk13"
                     /locus_tag="spr0464"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="NP_358058.1"
                     /db_xref="GI:15902508"
                     /db_xref="GeneID:933263"
     gene            complement(471895..472050)
                     /gene="ip"
                     /locus_tag="spr0465"
                     /db_xref="GeneID:933743"
     CDS             complement(471895..472050)
                     /gene="ip"
                     /locus_tag="spr0465"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide pheromone BlpC"
                     /protein_id="NP_358059.1"
                     /db_xref="GI:15902509"
                     /db_xref="GeneID:933743"
     gene            complement(472107..473468)
                     /locus_tag="spr0466"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933130"
     gene            complement(473479..475636)
                     /locus_tag="spr0468"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933924"
     gene            475926..476159
                     /locus_tag="spr0470"
                     /db_xref="GeneID:933339"
     CDS             475926..476159
                     /locus_tag="spr0470"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358064.1"
                     /db_xref="GI:15902514"
                     /db_xref="GeneID:933339"
     gene            476175..476354
                     /locus_tag="spr0471"
                     /db_xref="GeneID:932909"
     CDS             476175..476354
                     /locus_tag="spr0471"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358065.1"
                     /db_xref="GI:15902515"
                     /db_xref="GeneID:932909"
     gene            476191..476880
                     /gene="blpY"
                     /locus_tag="spr0472"
                     /db_xref="GeneID:933857"
     CDS             476191..476880
                     /gene="blpY"
                     /locus_tag="spr0472"
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein BlpY"
                     /protein_id="NP_358066.1"
                     /db_xref="GI:15902516"
                     /db_xref="GeneID:933857"
     gene            476922..477155
                     /gene="blpZ"
                     /locus_tag="spr0473"
                     /db_xref="GeneID:933043"
     CDS             476922..477155
                     /gene="blpZ"
                     /locus_tag="spr0473"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358067.1"
                     /db_xref="GI:15902517"
                     /db_xref="GeneID:933043"
     repeat_region   complement(477126..477230)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            477306..477917
                     /gene="pncP"
                     /locus_tag="spr0474"
                     /db_xref="GeneID:933556"
     CDS             477306..477917
                     /gene="pncP"
                     /locus_tag="spr0474"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358068.1"
                     /db_xref="GI:15902518"
                     /db_xref="GeneID:933556"
     gene            478078..478872
                     /locus_tag="spr0475"
                     /db_xref="GeneID:933194"
     CDS             478078..478872
                     /locus_tag="spr0475"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358069.1"
                     /db_xref="GI:15902519"
                     /db_xref="GeneID:933194"
     gene            478869..479504
                     /gene="trmB"
                     /locus_tag="spr0476"
                     /gene_synonym="yggH"
                     /db_xref="GeneID:933048"
     CDS             478869..479504
                     /gene="trmB"
                     /locus_tag="spr0476"
                     /gene_synonym="yggH"
                     /EC_number="2.1.1.33"
                     /note="tRNA (guanine-N(7)-)-methyltransferase; catalyzes
                     the formation of N(7)-methylguanine at position 46 (m7G46)
                     in tRNA by transferring the methyl residue from
                     S-adenosyl-L-methionine"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N(7)-)-methyltransferase"
                     /protein_id="NP_358070.1"
                     /db_xref="GI:15902520"
                     /db_xref="GeneID:933048"
     gene            479630..480109
                     /locus_tag="spr0477"
                     /db_xref="GeneID:933553"
     CDS             479630..480109
                     /locus_tag="spr0477"
                     /note="in Streptococcus pneumoniae this gene was found to
                     be essential; structure determination of the Streptococcus
                     protein shows that it is similar to a number of other
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358071.1"
                     /db_xref="GI:15902521"
                     /db_xref="GeneID:933553"
     gene            480153..481289
                     /gene="nusA"
                     /locus_tag="spr0478"
                     /db_xref="GeneID:933557"
     CDS             480153..481289
                     /gene="nusA"
                     /locus_tag="spr0478"
                     /note="modifies transcription through interactions with
                     RNA polymerase affecting elongation, readthrough,
                     termination, and antitermination"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor NusA"
                     /protein_id="NP_358072.1"
                     /db_xref="GI:15902522"
                     /db_xref="GeneID:933557"
     gene            481311..481604
                     /locus_tag="spr0479"
                     /db_xref="GeneID:933559"
     CDS             481311..481604
                     /locus_tag="spr0479"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358073.1"
                     /db_xref="GI:15902523"
                     /db_xref="GeneID:933559"
     gene            481597..481896
                     /locus_tag="spr0480"
                     /db_xref="GeneID:933550"
     CDS             481597..481896
                     /locus_tag="spr0480"
                     /note="Probable ribosomal protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358074.1"
                     /db_xref="GI:15902524"
                     /db_xref="GeneID:933550"
     gene            481913..484705
                     /gene="infB"
                     /locus_tag="spr0481"
                     /db_xref="GeneID:933555"
     CDS             481913..484705
                     /gene="infB"
                     /locus_tag="spr0481"
                     /note="Protects formylmethionyl-tRNA from spontaneous
                     hydrolysis and promotes its binding to the 30S ribosomal
                     subunits during initiation of protein synthesis. Also
                     involved in the hydrolysis of GTP during the formation of
                     the 70S ribosomal complex"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="NP_358075.1"
                     /db_xref="GI:15902525"
                     /db_xref="GeneID:933555"
     gene            484929..485306
                     /gene="rbfA"
                     /locus_tag="spr0482"
                     /db_xref="GeneID:933554"
     CDS             484929..485306
                     /gene="rbfA"
                     /locus_tag="spr0482"
                     /note="associates with free 30S ribosomal subunits;
                     essential for efficient processing of 16S rRNA; in
                     Escherichia coli rbfA is induced by cold shock"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-binding factor A"
                     /protein_id="NP_358076.1"
                     /db_xref="GI:15902526"
                     /db_xref="GeneID:933554"
     repeat_region   485376..485482
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            485549..486364
                     /locus_tag="spr0483"
                     /db_xref="GeneID:933552"
     CDS             485549..486364
                     /locus_tag="spr0483"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358077.1"
                     /db_xref="GI:15902527"
                     /db_xref="GeneID:933552"
     gene            486366..486548
                     /locus_tag="spr0484"
                     /db_xref="GeneID:933551"
     CDS             486366..486548
                     /locus_tag="spr0484"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358078.1"
                     /db_xref="GI:15902528"
                     /db_xref="GeneID:933551"
     repeat_region   486780..486974
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbbc"
     gene            486986..487231
                     /locus_tag="spr0485"
                     /db_xref="GeneID:933549"
     CDS             486986..487231
                     /locus_tag="spr0485"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358079.1"
                     /db_xref="GI:15902529"
                     /db_xref="GeneID:933549"
     gene            487231..488565
                     /locus_tag="spr0486"
                     /db_xref="GeneID:933548"
     CDS             487231..488565
                     /locus_tag="spr0486"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358080.1"
                     /db_xref="GI:15902530"
                     /db_xref="GeneID:933548"
     gene            488575..488829
                     /locus_tag="spr0487"
                     /db_xref="GeneID:933542"
     CDS             488575..488829
                     /locus_tag="spr0487"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358081.1"
                     /db_xref="GI:15902531"
                     /db_xref="GeneID:933542"
     gene            488925..489320
                     /locus_tag="spr0488"
                     /db_xref="GeneID:933547"
     CDS             488925..489320
                     /locus_tag="spr0488"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358082.1"
                     /db_xref="GI:15902532"
                     /db_xref="GeneID:933547"
     gene            489732..490181
                     /locus_tag="spr0489"
                     /db_xref="GeneID:933546"
     CDS             489732..490181
                     /locus_tag="spr0489"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358083.1"
                     /db_xref="GI:15902533"
                     /db_xref="GeneID:933546"
     gene            490168..490725
                     /locus_tag="spr0490"
                     /db_xref="GeneID:933539"
     CDS             490168..490725
                     /locus_tag="spr0490"
                     /note="Probable acetyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358084.1"
                     /db_xref="GI:15902534"
                     /db_xref="GeneID:933539"
     gene            490727..491689
                     /locus_tag="spr0491"
                     /db_xref="GeneID:933545"
     CDS             490727..491689
                     /locus_tag="spr0491"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358085.1"
                     /db_xref="GI:15902535"
                     /db_xref="GeneID:933545"
     gene            491701..494352
                     /gene="valS"
                     /locus_tag="spr0492"
                     /db_xref="GeneID:933544"
     CDS             491701..494352
                     /gene="valS"
                     /locus_tag="spr0492"
                     /EC_number="6.1.1.9"
                     /note="valine--tRNA ligase; ValRS; converts valine ATP and
                     tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I
                     aminoacyl-tRNA synthetase type 1 subfamily; has a
                     posttransfer editing process to hydrolyze mischarged
                     Thr-tRNA(Val) which is done by the editing domain"
                     /codon_start=1
                     /transl_table=11
                     /product="valyl-tRNA synthetase"
                     /protein_id="NP_358086.1"
                     /db_xref="GI:15902536"
                     /db_xref="GeneID:933544"
     gene            494407..495177
                     /locus_tag="spr0493"
                     /db_xref="GeneID:933536"
     CDS             494407..495177
                     /locus_tag="spr0493"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358087.1"
                     /db_xref="GI:15902537"
                     /db_xref="GeneID:933536"
     gene            495460..496263
                     /locus_tag="spr0494"
                     /db_xref="GeneID:933541"
     CDS             495460..496263
                     /locus_tag="spr0494"
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic-related protein"
                     /protein_id="NP_358088.1"
                     /db_xref="GI:15902538"
                     /db_xref="GeneID:933541"
     gene            complement(496379..497191)
                     /gene="IS861-truncation"
                     /locus_tag="spr0495"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933540"
     gene            complement(497417..497686)
                     /locus_tag="spr0499a"
                     /db_xref="GeneID:19592988"
     CDS             complement(497417..497686)
                     /locus_tag="spr0499a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008869153.1"
                     /db_xref="GI:651852204"
                     /db_xref="GeneID:19592988"
     gene            497816..498883
                     /locus_tag="spr0499"
                     /db_xref="GeneID:933531"
     CDS             497816..498883
                     /locus_tag="spr0499"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358093.1"
                     /db_xref="GI:15902543"
                     /db_xref="GeneID:933531"
     repeat_region   498860..498966
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            498980..500571
                     /locus_tag="spr0500"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933535"
     gene            500872..501711
                     /gene="licT"
                     /locus_tag="spr0504"
                     /db_xref="GeneID:933525"
     CDS             500872..501711
                     /gene="licT"
                     /locus_tag="spr0504"
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcriptional antiterminator"
                     /protein_id="NP_358098.1"
                     /db_xref="GI:15902548"
                     /db_xref="GeneID:933525"
     gene            501729..503567
                     /gene="PTS-EII"
                     /locus_tag="spr0505"
                     /db_xref="GeneID:933530"
     CDS             501729..503567
                     /gene="PTS-EII"
                     /locus_tag="spr0505"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system beta-glucosides-specific transporter
                     subunit IIABC"
                     /protein_id="NP_358099.1"
                     /db_xref="GI:15902549"
                     /db_xref="GeneID:933530"
     gene            503580..504995
                     /gene="bglH"
                     /locus_tag="spr0506"
                     /db_xref="GeneID:933529"
     CDS             503580..504995
                     /gene="bglH"
                     /locus_tag="spr0506"
                     /EC_number="3.2.1.86"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="NP_358100.1"
                     /db_xref="GI:15902550"
                     /db_xref="GeneID:933529"
     repeat_region   505173..505279
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     gene            505587..506633
                     /gene="pheS"
                     /locus_tag="spr0507"
                     /db_xref="GeneID:933527"
     CDS             505587..506633
                     /gene="pheS"
                     /locus_tag="spr0507"
                     /EC_number="6.1.1.20"
                     /note="catalyzes a two-step reaction, first charging a
                     phenylalanine molecule by linking its carboxyl group to
                     the alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; forms a heterotetramer of
                     alpha(2)beta(2); binds two magnesium ions per tetramer;
                     type 1 subfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="NP_358101.2"
                     /db_xref="GI:161410752"
                     /db_xref="GeneID:933527"
     gene            506633..507142
                     /locus_tag="spr0508"
                     /db_xref="GeneID:933526"
     CDS             506633..507142
                     /locus_tag="spr0508"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358102.1"
                     /db_xref="GI:15902552"
                     /db_xref="GeneID:933526"
     gene            507219..509621
                     /gene="pheT"
                     /locus_tag="spr0509"
                     /db_xref="GeneID:933519"
     CDS             507219..509621
                     /gene="pheT"
                     /locus_tag="spr0509"
                     /EC_number="6.1.1.20"
                     /note="catalyzes a two-step reaction, first charging a
                     phenylalanine molecule by linking its carboxyl group to
                     the alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; forms a tetramer of
                     alpha(2)beta(2); binds two magnesium ions per tetramer;
                     type 2 subfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit beta"
                     /protein_id="NP_358103.1"
                     /db_xref="GI:15902553"
                     /db_xref="GeneID:933519"
     gene            complement(509689..510690)
                     /locus_tag="spr0510"
                     /db_xref="GeneID:933523"
     CDS             complement(509689..510690)
                     /locus_tag="spr0510"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358104.1"
                     /db_xref="GI:15902554"
                     /db_xref="GeneID:933523"
     gene            510846..511341
                     /gene="IS1239-truncation"
                     /locus_tag="spr0511"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933522"
     gene            511419..511685
                     /locus_tag="spr0513"
                     /db_xref="GeneID:933521"
     CDS             511419..511685
                     /locus_tag="spr0513"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358107.1"
                     /db_xref="GI:15902557"
                     /db_xref="GeneID:933521"
     gene            511802..514195
                     /gene="metE"
                     /locus_tag="spr0514"
                     /db_xref="GeneID:933520"
     CDS             511802..514195
                     /gene="metE"
                     /locus_tag="spr0514"
                     /EC_number="2.1.1.14"
                     /note="catalyzes the transfer of a methyl group from
                     5-methyltetrahydrofolate to homocysteine to form
                     methionine"
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="NP_358108.1"
                     /db_xref="GI:15902558"
                     /db_xref="GeneID:933520"
     gene            514259..515125
                     /gene="metF"
                     /locus_tag="spr0515"
                     /db_xref="GeneID:933513"
     CDS             514259..515125
                     /gene="metF"
                     /locus_tag="spr0515"
                     /EC_number="1.5.1.20"
                     /codon_start=1
                     /transl_table=11
                     /product="5,10-methylenetetrahydrofolate reductase"
                     /protein_id="NP_358109.1"
                     /db_xref="GI:15902559"
                     /db_xref="GeneID:933513"
     gene            515696..518023
                     /gene="pnpA"
                     /locus_tag="spr0516"
                     /db_xref="GeneID:933518"
     CDS             515696..518023
                     /gene="pnpA"
                     /locus_tag="spr0516"
                     /EC_number="2.7.7.8"
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide phosphorylase"
                     /protein_id="NP_358110.1"
                     /db_xref="GI:15902560"
                     /db_xref="GeneID:933518"
     gene            518039..518656
                     /gene="cysE"
                     /locus_tag="spr0517"
                     /db_xref="GeneID:933517"
     CDS             518039..518656
                     /gene="cysE"
                     /locus_tag="spr0517"
                     /EC_number="2.3.1.30"
                     /codon_start=1
                     /transl_table=11
                     /product="serine acetyltransferase"
                     /protein_id="NP_358111.1"
                     /db_xref="GI:15902561"
                     /db_xref="GeneID:933517"
     gene            518668..519552
                     /locus_tag="spr0518"
                     /db_xref="GeneID:933510"
     CDS             518668..519552
                     /locus_tag="spr0518"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358112.1"
                     /db_xref="GI:15902562"
                     /db_xref="GeneID:933510"
     gene            519634..520977
                     /gene="cysS"
                     /locus_tag="spr0519"
                     /db_xref="GeneID:933515"
     CDS             519634..520977
                     /gene="cysS"
                     /locus_tag="spr0519"
                     /EC_number="6.1.1.16"
                     /note="catalyzes a two-step reaction; charges a cysteine
                     by linking its carboxyl group to the alpha-phosphate of
                     ATP then transfers the aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteinyl-tRNA synthetase"
                     /protein_id="NP_358113.1"
                     /db_xref="GI:15902563"
                     /db_xref="GeneID:933515"
     gene            520970..521356
                     /locus_tag="spr0520"
                     /db_xref="GeneID:933514"
     CDS             520970..521356
                     /locus_tag="spr0520"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358114.1"
                     /db_xref="GI:15902564"
                     /db_xref="GeneID:933514"
     gene            521360..522244
                     /locus_tag="spr0521"
                     /db_xref="GeneID:933507"
     CDS             521360..522244
                     /locus_tag="spr0521"
                     /note="Leucine rich protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358115.1"
                     /db_xref="GI:15902565"
                     /db_xref="GeneID:933507"
     gene            522381..522979
                     /locus_tag="spr0522"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933512"
     gene            523125..523511
                     /gene="transposase_H-truncation"
                     /locus_tag="spr0523"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933511"
     repeat_region   complement(523291..523397)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            523650..524927
                     /gene="vex1"
                     /locus_tag="spr0524"
                     /db_xref="GeneID:933509"
     CDS             523650..524927
                     /gene="vex1"
                     /locus_tag="spr0524"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="NP_358118.1"
                     /db_xref="GI:15902568"
                     /db_xref="GeneID:933509"
     gene            524940..525587
                     /gene="vex2"
                     /locus_tag="spr0525"
                     /db_xref="GeneID:933508"
     CDS             524940..525587
                     /gene="vex2"
                     /locus_tag="spr0525"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358119.1"
                     /db_xref="GI:15902569"
                     /db_xref="GeneID:933508"
     gene            525639..527018
                     /gene="vex3"
                     /locus_tag="spr0526"
                     /db_xref="GeneID:933495"
     CDS             525639..527018
                     /gene="vex3"
                     /locus_tag="spr0526"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="NP_358120.1"
                     /db_xref="GI:15902570"
                     /db_xref="GeneID:933495"
     misc_feature    527198..527281
                     /note="similar to signal peptide"
     gene            527330..527986
                     /gene="vncR"
                     /locus_tag="spr0528"
                     /db_xref="GeneID:933502"
     CDS             527330..527986
                     /gene="vncR"
                     /locus_tag="spr0528"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator VncR"
                     /protein_id="NP_358122.1"
                     /db_xref="GI:15902572"
                     /db_xref="GeneID:933502"
     gene            527983..529311
                     /gene="vncS"
                     /locus_tag="spr0529"
                     /db_xref="GeneID:933480"
     CDS             527983..529311
                     /gene="vncS"
                     /locus_tag="spr0529"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase VncS"
                     /protein_id="NP_358123.1"
                     /db_xref="GI:15902573"
                     /db_xref="GeneID:933480"
     gene            529452..530333
                     /gene="fba"
                     /locus_tag="spr0530"
                     /db_xref="GeneID:933499"
     CDS             529452..530333
                     /gene="fba"
                     /locus_tag="spr0530"
                     /EC_number="4.1.2.13"
                     /note="catalyzes the formation of glycerone phosphate and
                     glyceraldehyde 3-phosphate from fructose 1,6,
                     bisphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="NP_358124.1"
                     /db_xref="GI:15902574"
                     /db_xref="GeneID:933499"
     gene            complement(530654..531856)
                     /locus_tag="spr0531"
                     /db_xref="GeneID:933496"
     CDS             complement(530654..531856)
                     /locus_tag="spr0531"
                     /note="Probable oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_358125.1"
                     /db_xref="GI:15902575"
                     /db_xref="GeneID:933496"
     repeat_region   complement(531988..532100)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(532102..532761)
                     /gene="glnP"
                     /locus_tag="spr0532"
                     /db_xref="GeneID:933482"
     CDS             complement(532102..532761)
                     /gene="glnP"
                     /locus_tag="spr0532"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358126.1"
                     /db_xref="GI:15902576"
                     /db_xref="GeneID:933482"
     gene            complement(532771..533448)
                     /gene="glnP"
                     /locus_tag="spr0533"
                     /db_xref="GeneID:933485"
     CDS             complement(532771..533448)
                     /gene="glnP"
                     /locus_tag="spr0533"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358127.1"
                     /db_xref="GI:15902577"
                     /db_xref="GeneID:933485"
     gene            complement(533461..534255)
                     /gene="glnH"
                     /locus_tag="spr0534"
                     /db_xref="GeneID:933401"
     CDS             complement(533461..534255)
                     /gene="glnH"
                     /locus_tag="spr0534"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter amino acid-binding
                     protein"
                     /protein_id="NP_358128.1"
                     /db_xref="GI:15902578"
                     /db_xref="GeneID:933401"
     gene            complement(534266..535024)
                     /gene="glnQ-truncation"
                     /locus_tag="spr0535"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933476"
     repeat_region   complement(535114..535210)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            535289..537523
                     /gene="recJ"
                     /locus_tag="spr0537"
                     /db_xref="GeneID:933422"
     CDS             535289..537523
                     /gene="recJ"
                     /locus_tag="spr0537"
                     /EC_number="3.1.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="NP_358131.1"
                     /db_xref="GI:15902581"
                     /db_xref="GeneID:933422"
     gene            537698..539359
                     /locus_tag="spr0538"
                     /db_xref="GeneID:933405"
     CDS             537698..539359
                     /locus_tag="spr0538"
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-beta-lactamase superfamily protein"
                     /protein_id="NP_358132.1"
                     /db_xref="GI:15902582"
                     /db_xref="GeneID:933405"
     gene            539428..540207
                     /gene="estA"
                     /locus_tag="spr0539"
                     /db_xref="GeneID:933384"
     CDS             539428..540207
                     /gene="estA"
                     /locus_tag="spr0539"
                     /codon_start=1
                     /transl_table=11
                     /product="tributyrin esterase"
                     /protein_id="NP_358133.1"
                     /db_xref="GI:15902583"
                     /db_xref="GeneID:933384"
     gene            540319..541539
                     /gene="murM"
                     /locus_tag="spr0540"
                     /db_xref="GeneID:933395"
     CDS             540319..541539
                     /gene="murM"
                     /locus_tag="spr0540"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/alanine adding enzyme"
                     /protein_id="NP_358134.1"
                     /db_xref="GI:15902584"
                     /db_xref="GeneID:933395"
     gene            541544..542776
                     /gene="murN"
                     /locus_tag="spr0541"
                     /db_xref="GeneID:933396"
     CDS             541544..542776
                     /gene="murN"
                     /locus_tag="spr0541"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactam resistance factor"
                     /protein_id="NP_358135.1"
                     /db_xref="GI:15902585"
                     /db_xref="GeneID:933396"
     gene            542892..543551
                     /locus_tag="spr0542"
                     /db_xref="GeneID:933380"
     CDS             542892..543551
                     /locus_tag="spr0542"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358136.1"
                     /db_xref="GI:15902586"
                     /db_xref="GeneID:933380"
     gene            543591..545435
                     /gene="uvrC"
                     /locus_tag="spr0543"
                     /db_xref="GeneID:933390"
     CDS             543591..545435
                     /gene="uvrC"
                     /locus_tag="spr0543"
                     /note="The UvrABC repair system catalyzes the recognition
                     and processing of DNA lesions. UvrC both incises the 5'
                     and 3' sides of the lesion. The N-terminal half is
                     responsible for the 3' incision and the C-terminal half is
                     responsible for the 5' incision"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit C"
                     /protein_id="NP_358137.1"
                     /db_xref="GI:15902587"
                     /db_xref="GeneID:933390"
     gene            545425..546258
                     /locus_tag="spr0544"
                     /db_xref="GeneID:933388"
     CDS             545425..546258
                     /locus_tag="spr0544"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358138.1"
                     /db_xref="GI:15902588"
                     /db_xref="GeneID:933388"
     repeat_region   complement(546326..546438)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(546440..547255)
                     /gene="ABC-SBP"
                     /locus_tag="spr0545"
                     /db_xref="GeneID:933383"
     CDS             complement(546440..547255)
                     /gene="ABC-SBP"
                     /locus_tag="spr0545"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358139.1"
                     /db_xref="GI:15902589"
                     /db_xref="GeneID:933383"
     gene            547411..548016
                     /gene="nrd"
                     /locus_tag="spr0546"
                     /db_xref="GeneID:933381"
     CDS             547411..548016
                     /gene="nrd"
                     /locus_tag="spr0546"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="NP_358140.1"
                     /db_xref="GI:15902590"
                     /db_xref="GeneID:933381"
     gene            548029..549429
                     /gene="pepV"
                     /locus_tag="spr0547"
                     /db_xref="GeneID:933367"
     CDS             548029..549429
                     /gene="pepV"
                     /locus_tag="spr0547"
                     /EC_number="3.4.14.-"
                     /note="divalent metal ion-dependent extracellular
                     dipeptidase; able to hydrolyze a broad range of dipeptides
                     but no tri-, tetra-, or larger oligopeptides; differences
                     in the amino acid specificity of the cleavage site varies
                     between species; similar to succinyl-diaminopimelate
                     desuccinylases"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="NP_358141.1"
                     /db_xref="GI:15902591"
                     /db_xref="GeneID:933367"
     gene            549483..550061
                     /locus_tag="spr0548"
                     /db_xref="GeneID:933378"
     CDS             549483..550061
                     /locus_tag="spr0548"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358142.1"
                     /db_xref="GI:15902592"
                     /db_xref="GeneID:933378"
     repeat_region   complement(550056..550206)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            550668..552008
                     /gene="brnQ"
                     /locus_tag="spr0551"
                     /db_xref="GeneID:933369"
     CDS             550668..552008
                     /gene="brnQ"
                     /locus_tag="spr0551"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     carrier protein"
                     /protein_id="NP_358145.1"
                     /db_xref="GI:15902595"
                     /db_xref="GeneID:933369"
     repeat_region   552013..552121
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     gene            552212..553249
                     /locus_tag="spr0552"
                     /db_xref="GeneID:933366"
     CDS             552212..553249
                     /locus_tag="spr0552"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358146.1"
                     /db_xref="GI:15902596"
                     /db_xref="GeneID:933366"
     gene            553218..553721
                     /locus_tag="spr0553"
                     /db_xref="GeneID:933365"
     CDS             553218..553721
                     /locus_tag="spr0553"
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="NP_358147.1"
                     /db_xref="GI:15902597"
                     /db_xref="GeneID:933365"
     gene            553724..554440
                     /locus_tag="spr0554"
                     /db_xref="GeneID:933353"
     CDS             553724..554440
                     /locus_tag="spr0554"
                     /note="carboxypeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358148.1"
                     /db_xref="GI:15902598"
                     /db_xref="GeneID:933353"
     repeat_region   554438..554623
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            554749..555174
                     /gene="rplK"
                     /locus_tag="spr0555"
                     /db_xref="GeneID:933360"
     CDS             554749..555174
                     /gene="rplK"
                     /locus_tag="spr0555"
                     /note="binds directly to 23S ribosomal RNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="NP_358149.1"
                     /db_xref="GI:15902599"
                     /db_xref="GeneID:933360"
     gene            555382..556071
                     /gene="rplA"
                     /locus_tag="spr0556"
                     /db_xref="GeneID:933347"
     CDS             555382..556071
                     /gene="rplA"
                     /locus_tag="spr0556"
                     /note="in Escherichia coli and Methanococcus, this protein
                     autoregulates expression; the binding site in the mRNA
                     mimics the binding site in the 23S rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="NP_358150.1"
                     /db_xref="GI:15902600"
                     /db_xref="GeneID:933347"
     repeat_region   complement(556333..556439)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   556664..557178
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbbbbbbbbc"
     repeat_region   557770..557876
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     gene            558589..559581
                     /gene="ABC-NBD"
                     /locus_tag="spr0557"
                     /db_xref="GeneID:933350"
     CDS             558589..559581
                     /gene="ABC-NBD"
                     /locus_tag="spr0557"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358151.1"
                     /db_xref="GI:15902601"
                     /db_xref="GeneID:933350"
     gene            559541..560401
                     /locus_tag="spr0558"
                     /db_xref="GeneID:933348"
     CDS             559541..560401
                     /locus_tag="spr0558"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358152.1"
                     /db_xref="GI:15902602"
                     /db_xref="GeneID:933348"
     gene            560403..561188
                     /locus_tag="spr0559"
                     /db_xref="GeneID:933329"
     CDS             560403..561188
                     /locus_tag="spr0559"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358153.1"
                     /db_xref="GI:15902603"
                     /db_xref="GeneID:933329"
     gene            561441..561686
                     /locus_tag="spr0560"
                     /db_xref="GeneID:933343"
     CDS             561441..561686
                     /locus_tag="spr0560"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358154.1"
                     /db_xref="GI:15902604"
                     /db_xref="GeneID:933343"
     gene            complement(561962..562186)
                     /locus_tag="spr0560a"
                     /db_xref="GeneID:17374505"
     CDS             complement(561962..562186)
                     /locus_tag="spr0560a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719800.1"
                     /db_xref="GI:555247346"
                     /db_xref="GeneID:17374505"
     repeat_region   561998..562192
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            562418..568852
                     /gene="prtA"
                     /locus_tag="spr0561"
                     /db_xref="GeneID:933322"
     CDS             562418..568852
                     /gene="prtA"
                     /locus_tag="spr0561"
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-associated serine proteinase PrtA"
                     /protein_id="NP_358155.1"
                     /db_xref="GI:15902605"
                     /db_xref="GeneID:933322"
     repeat_region   569213..569257
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            569431..569952
                     /gene="PTS-EII"
                     /locus_tag="spr0562"
                     /db_xref="GeneID:933332"
     CDS             569431..569952
                     /gene="PTS-EII"
                     /locus_tag="spr0562"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_358156.1"
                     /db_xref="GI:15902606"
                     /db_xref="GeneID:933332"
     gene            569990..570295
                     /locus_tag="spr0563"
                     /db_xref="GeneID:933317"
     CDS             569990..570295
                     /locus_tag="spr0563"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358157.1"
                     /db_xref="GI:15902607"
                     /db_xref="GeneID:933317"
     gene            570343..571818
                     /gene="PTS-EII"
                     /locus_tag="spr0564"
                     /db_xref="GeneID:933325"
     CDS             570343..571818
                     /gene="PTS-EII"
                     /locus_tag="spr0564"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_358158.1"
                     /db_xref="GI:15902608"
                     /db_xref="GeneID:933325"
     repeat_region   complement(571839..572014)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            572123..578809
                     /gene="bgaA"
                     /locus_tag="spr0565"
                     /db_xref="GeneID:933305"
     CDS             572123..578809
                     /gene="bgaA"
                     /locus_tag="spr0565"
                     /EC_number="3.2.1.23"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="NP_358159.1"
                     /db_xref="GI:15902609"
                     /db_xref="GeneID:933305"
     repeat_region   578968..579073
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(579057..579678)
                     /locus_tag="spr0566"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933319"
     gene            complement(579666..579911)
                     /locus_tag="spr0567"
                     /db_xref="GeneID:933300"
     CDS             complement(579666..579911)
                     /locus_tag="spr0567"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358161.1"
                     /db_xref="GI:15902611"
                     /db_xref="GeneID:933300"
     gene            complement(580123..580482)
                     /locus_tag="spr0568"
                     /db_xref="GeneID:933310"
     CDS             complement(580123..580482)
                     /locus_tag="spr0568"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358162.1"
                     /db_xref="GI:15902612"
                     /db_xref="GeneID:933310"
     gene            580406..581026
                     /locus_tag="spr0569"
                     /db_xref="GeneID:933312"
     CDS             580406..581026
                     /locus_tag="spr0569"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358163.1"
                     /db_xref="GI:15902613"
                     /db_xref="GeneID:933312"
     gene            581084..581530
                     /locus_tag="spr0570"
                     /db_xref="GeneID:933299"
     CDS             581084..581530
                     /locus_tag="spr0570"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358164.1"
                     /db_xref="GI:15902614"
                     /db_xref="GeneID:933299"
     gene            581508..582071
                     /locus_tag="spr0571"
                     /db_xref="GeneID:933303"
     CDS             581508..582071
                     /locus_tag="spr0571"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358165.1"
                     /db_xref="GI:15902615"
                     /db_xref="GeneID:933303"
     gene            582064..582318
                     /locus_tag="spr0572"
                     /db_xref="GeneID:933301"
     CDS             582064..582318
                     /locus_tag="spr0572"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358166.1"
                     /db_xref="GI:15902616"
                     /db_xref="GeneID:933301"
     gene            582330..584384
                     /gene="nha2"
                     /locus_tag="spr0573"
                     /db_xref="GeneID:933286"
     CDS             582330..584384
                     /gene="nha2"
                     /locus_tag="spr0573"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/hydrogen exchanger family protein"
                     /protein_id="NP_358167.1"
                     /db_xref="GI:15902617"
                     /db_xref="GeneID:933286"
     repeat_region   584386..584539
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            584548..585423
                     /locus_tag="spr0574"
                     /db_xref="GeneID:933297"
     CDS             584548..585423
                     /locus_tag="spr0574"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="NP_358168.1"
                     /db_xref="GI:15902618"
                     /db_xref="GeneID:933297"
     gene            585634..586344
                     /gene="ccdA"
                     /locus_tag="spr0575"
                     /db_xref="GeneID:933280"
     CDS             585634..586344
                     /gene="ccdA"
                     /locus_tag="spr0575"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein"
                     /protein_id="NP_358169.1"
                     /db_xref="GI:15902619"
                     /db_xref="GeneID:933280"
     gene            586337..586930
                     /locus_tag="spr0576"
                     /db_xref="GeneID:933294"
     CDS             586337..586930
                     /locus_tag="spr0576"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358170.1"
                     /db_xref="GI:15902620"
                     /db_xref="GeneID:933294"
     gene            586941..588053
                     /gene="msrA"
                     /locus_tag="spr0577"
                     /db_xref="GeneID:933291"
     CDS             586941..588053
                     /gene="msrA"
                     /locus_tag="spr0577"
                     /note="this fusion consists of methionine sulfoxide A
                     reductase at the N-terminus and B at the C-terminus; A and
                     B are stereospecific enzymes that recognize the damaged
                     produces of oxidative stress, S and R epimers of
                     methionine sulfoxide, respectively; a fusion"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methionine sulfoxide reductase A/B
                     protein"
                     /protein_id="NP_358171.1"
                     /db_xref="GI:15902621"
                     /db_xref="GeneID:933291"
     repeat_region   588051..588250
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            588303..589058
                     /gene="rr09"
                     /locus_tag="spr0578"
                     /db_xref="GeneID:933285"
     CDS             588303..589058
                     /gene="rr09"
                     /locus_tag="spr0578"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_358172.1"
                     /db_xref="GI:15902622"
                     /db_xref="GeneID:933285"
     gene            589055..590746
                     /gene="hk09"
                     /locus_tag="spr0579"
                     /db_xref="GeneID:933281"
     CDS             589055..590746
                     /gene="hk09"
                     /locus_tag="spr0579"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="NP_358173.1"
                     /db_xref="GI:15902623"
                     /db_xref="GeneID:933281"
     gene            590841..591425
                     /locus_tag="spr0580"
                     /db_xref="GeneID:933233"
     CDS             590841..591425
                     /locus_tag="spr0580"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358174.1"
                     /db_xref="GI:15902624"
                     /db_xref="GeneID:933233"
     gene            591447..597077
                     /gene="zmpB"
                     /locus_tag="spr0581"
                     /db_xref="GeneID:933274"
     CDS             591447..597077
                     /gene="zmpB"
                     /locus_tag="spr0581"
                     /note="Similar to IgA1 protease"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease"
                     /protein_id="NP_358175.1"
                     /db_xref="GI:15902625"
                     /db_xref="GeneID:933274"
     gene            597147..598868
                     /gene="pabB"
                     /locus_tag="spr0582"
                     /db_xref="GeneID:933270"
     CDS             597147..598868
                     /gene="pabB"
                     /locus_tag="spr0582"
                     /EC_number="4.1.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="Para-aminobenzoate synthetase"
                     /protein_id="NP_358176.1"
                     /db_xref="GI:15902626"
                     /db_xref="GeneID:933270"
     gene            599026..600015
                     /locus_tag="spr0583"
                     /db_xref="GeneID:933221"
     CDS             599026..600015
                     /locus_tag="spr0583"
                     /note="Similar to 1,4-beta-N-acetylmuramidase"
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal surface protein"
                     /protein_id="NP_358177.1"
                     /db_xref="GI:15902627"
                     /db_xref="GeneID:933221"
     gene            600133..601110
                     /gene="glcK"
                     /locus_tag="spr0584"
                     /db_xref="GeneID:933239"
     CDS             600133..601110
                     /gene="glcK"
                     /locus_tag="spr0584"
                     /EC_number="2.7.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="NP_358178.1"
                     /db_xref="GI:15902628"
                     /db_xref="GeneID:933239"
     gene            601207..602046
                     /gene="thyA"
                     /locus_tag="spr0585"
                     /db_xref="GeneID:933235"
     CDS             601207..602046
                     /gene="thyA"
                     /locus_tag="spr0585"
                     /EC_number="2.1.1.45"
                     /note="ThyA; catalyzes formation of dTMP and
                     7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and
                     dUMP; involved in deoxyribonucleotide biosynthesis; there
                     are 2 copies in some Bacilli, one of which appears to be
                     phage-derived"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="NP_358179.1"
                     /db_xref="GI:15902629"
                     /db_xref="GeneID:933235"
     gene            complement(602094..602264)
                     /locus_tag="spr0586"
                     /db_xref="GeneID:933200"
     CDS             complement(602094..602264)
                     /locus_tag="spr0586"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358180.1"
                     /db_xref="GI:15902630"
                     /db_xref="GeneID:933200"
     gene            602334..603269
                     /gene="miaA"
                     /locus_tag="spr0588"
                     /db_xref="GeneID:933224"
     CDS             602334..603269
                     /gene="miaA"
                     /locus_tag="spr0588"
                     /EC_number="2.5.1.75"
                     /note="IPP transferase; isopentenyltransferase; involved
                     in tRNA modification; in Escherichia coli this enzyme
                     catalyzes the addition of a delta2-isopentenyl group from
                     dimethylallyl diphosphate to the N6-nitrogen of adenosine
                     adjacent to the anticodon of tRNA species that read codons
                     starting with uracil; further tRNA modifications may
                     occur; mutations in miaA result in defects in translation
                     efficiency and fidelity"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA delta(2)-isopentenylpyrophosphate
                     transferase"
                     /protein_id="NP_358182.1"
                     /db_xref="GI:15902632"
                     /db_xref="GeneID:933224"
     gene            603262..604500
                     /locus_tag="spr0589"
                     /db_xref="GeneID:933192"
     CDS             603262..604500
                     /locus_tag="spr0589"
                     /note="Probable GTP-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein HflX"
                     /protein_id="NP_358183.1"
                     /db_xref="GI:15902633"
                     /db_xref="GeneID:933192"
     gene            604493..605116
                     /locus_tag="spr0590"
                     /db_xref="GeneID:933210"
     CDS             604493..605116
                     /locus_tag="spr0590"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358184.1"
                     /db_xref="GI:15902634"
                     /db_xref="GeneID:933210"
     gene            605131..606060
                     /locus_tag="spr0591"
                     /db_xref="GeneID:933204"
     CDS             605131..606060
                     /locus_tag="spr0591"
                     /EC_number="3.1.26.11"
                     /note="member of metallo-beta-lactamase; the purified
                     enzyme from Escherichia coli forms dimeric zinc
                     phosphodiesterase; in Bacillus subtilis this protein is a
                     3'-tRNA processing endoribonuclease and is essential while
                     in Escherichia coli it is not; associates with two zinc
                     ions"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="NP_358185.1"
                     /db_xref="GI:15902635"
                     /db_xref="GeneID:933204"
     gene            606081..606836
                     /locus_tag="spr0592"
                     /db_xref="GeneID:933170"
     CDS             606081..606836
                     /locus_tag="spr0592"
                     /note="Probable oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358186.1"
                     /db_xref="GI:15902636"
                     /db_xref="GeneID:933170"
     gene            complement(606890..607936)
                     /gene="cpsY"
                     /locus_tag="spr0593"
                     /db_xref="GeneID:933196"
     CDS             complement(606890..607936)
                     /gene="cpsY"
                     /locus_tag="spr0593"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_358187.1"
                     /db_xref="GI:15902637"
                     /db_xref="GeneID:933196"
     gene            607862..608131
                     /locus_tag="spr0594"
                     /db_xref="GeneID:933197"
     CDS             607862..608131
                     /locus_tag="spr0594"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358188.1"
                     /db_xref="GI:15902638"
                     /db_xref="GeneID:933197"
     gene            608131..608511
                     /locus_tag="spr0595"
                     /db_xref="GeneID:933145"
     CDS             608131..608511
                     /locus_tag="spr0595"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358189.1"
                     /db_xref="GI:15902639"
                     /db_xref="GeneID:933145"
     gene            608630..608827
                     /locus_tag="spr0596"
                     /db_xref="GeneID:933177"
     CDS             608630..608827
                     /locus_tag="spr0596"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358190.1"
                     /db_xref="GI:15902640"
                     /db_xref="GeneID:933177"
     gene            complement(608867..609592)
                     /gene="rsuA"
                     /locus_tag="spr0597"
                     /db_xref="GeneID:933171"
     CDS             complement(608867..609592)
                     /gene="rsuA"
                     /locus_tag="spr0597"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal small subunit pseudouridine synthase
                     A"
                     /protein_id="NP_358191.1"
                     /db_xref="GI:15902641"
                     /db_xref="GeneID:933171"
     gene            609733..611595
                     /gene="typA"
                     /locus_tag="spr0598"
                     /db_xref="GeneID:933159"
     CDS             609733..611595
                     /gene="typA"
                     /locus_tag="spr0598"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu family protein"
                     /protein_id="NP_358192.1"
                     /db_xref="GI:15902642"
                     /db_xref="GeneID:933159"
     gene            611615..611869
                     /locus_tag="spr0599"
                     /db_xref="GeneID:933150"
     CDS             611615..611869
                     /locus_tag="spr0599"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358193.1"
                     /db_xref="GI:15902643"
                     /db_xref="GeneID:933150"
     gene            612185..612532
                     /locus_tag="spr0600"
                     /db_xref="GeneID:933142"
     CDS             612185..612532
                     /locus_tag="spr0600"
                     /note="bacteriocin"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358194.1"
                     /db_xref="GI:15902644"
                     /db_xref="GeneID:933142"
     gene            612603..614624
                     /locus_tag="spr0601"
                     /db_xref="GeneID:933021"
     CDS             612603..614624
                     /locus_tag="spr0601"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358195.1"
                     /db_xref="GI:15902645"
                     /db_xref="GeneID:933021"
     gene            614626..615267
                     /gene="ABC-NBD"
                     /locus_tag="spr0602"
                     /db_xref="GeneID:933012"
     CDS             614626..615267
                     /gene="ABC-NBD"
                     /locus_tag="spr0602"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium ABC transporter ATP-binding protein"
                     /protein_id="NP_358196.1"
                     /db_xref="GI:15902646"
                     /db_xref="GeneID:933012"
     gene            615371..616723
                     /gene="murD"
                     /locus_tag="spr0603"
                     /db_xref="GeneID:932998"
     CDS             615371..616723
                     /gene="murD"
                     /locus_tag="spr0603"
                     /EC_number="6.3.2.9"
                     /note="UDP-N-acetylmuramoylalanine--D-glutamate ligase;
                     involved in peptidoglycan biosynthesis; cytoplasmic;
                     catalyzes the addition of glutamate to the nucleotide
                     precursor UDP-N-acetylmuramoyl-L-alanine during cell wall
                     formation"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
                     synthetase"
                     /protein_id="NP_358197.1"
                     /db_xref="GI:15902647"
                     /db_xref="GeneID:932998"
     gene            616727..617785
                     /gene="murG"
                     /locus_tag="spr0604"
                     /db_xref="GeneID:933002"
     CDS             616727..617785
                     /gene="murG"
                     /locus_tag="spr0604"
                     /EC_number="2.4.1.227"
                     /note="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase; involved in cell wall
                     formation; inner membrane-associated; last step of
                     peptidoglycan synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N- acetylglucosaminyltransferase"
                     /protein_id="NP_358198.1"
                     /db_xref="GI:15902648"
                     /db_xref="GeneID:933002"
     gene            617795..618985
                     /gene="divIB"
                     /locus_tag="spr0605"
                     /db_xref="GeneID:932989"
     CDS             617795..618985
                     /gene="divIB"
                     /locus_tag="spr0605"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="NP_358199.1"
                     /db_xref="GI:15902649"
                     /db_xref="GeneID:932989"
     gene            619725..620573
                     /locus_tag="spr0607"
                     /db_xref="GeneID:932983"
     CDS             619725..620573
                     /locus_tag="spr0607"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358201.1"
                     /db_xref="GI:15902651"
                     /db_xref="GeneID:932983"
     gene            620557..621929
                     /locus_tag="spr0608"
                     /pseudogene="unknown"
                     /db_xref="GeneID:932977"
     gene            622097..622972
                     /gene="ABC-NBD-truncation"
                     /locus_tag="spr0609"
                     /pseudogene="unknown"
                     /db_xref="GeneID:932964"
     gene            622965..623678
                     /locus_tag="spr0611"
                     /db_xref="GeneID:932963"
     CDS             622965..623678
                     /locus_tag="spr0611"
                     /note="membrane spanning protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358205.1"
                     /db_xref="GI:15902655"
                     /db_xref="GeneID:932963"
     gene            624413..625114
                     /gene="pyrF"
                     /locus_tag="spr0613"
                     /db_xref="GeneID:932958"
     CDS             624413..625114
                     /gene="pyrF"
                     /locus_tag="spr0613"
                     /EC_number="4.1.1.23"
                     /note="OMP decarboxylase; OMPDCase; OMPdecase; type 1
                     subfamily; involved in last step of pyrimidine
                     biosynthesis; converts orotidine 5'-phosphate to UMP and
                     carbon dioxide; OMP decarboxylase; OMPDCase; OMPdecase"
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine 5'-phosphate decarboxylase"
                     /protein_id="NP_358207.1"
                     /db_xref="GI:15902657"
                     /db_xref="GeneID:932958"
     gene            625148..625780
                     /gene="pyrE"
                     /locus_tag="spr0614"
                     /db_xref="GeneID:932949"
     CDS             625148..625780
                     /gene="pyrE"
                     /locus_tag="spr0614"
                     /EC_number="2.4.2.10"
                     /note="involved in fifth step of pyrimidine biosynthesis;
                     converts orotidine 5'-phosphate and diphosphate to orotate
                     and 5-phospho-alpha-D-ribose 1-diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="NP_358208.1"
                     /db_xref="GI:15902658"
                     /db_xref="GeneID:932949"
     gene            625960..626364
                     /locus_tag="spr0615"
                     /db_xref="GeneID:934889"
     CDS             625960..626364
                     /locus_tag="spr0615"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358209.1"
                     /db_xref="GI:15902659"
                     /db_xref="GeneID:934889"
     gene            626460..627224
                     /locus_tag="spr0616"
                     /db_xref="GeneID:932946"
     CDS             626460..627224
                     /locus_tag="spr0616"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358210.1"
                     /db_xref="GI:15902660"
                     /db_xref="GeneID:932946"
     gene            627173..627976
                     /locus_tag="spr0617"
                     /db_xref="GeneID:932944"
     CDS             627173..627976
                     /locus_tag="spr0617"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358211.1"
                     /db_xref="GI:15902661"
                     /db_xref="GeneID:932944"
     gene            627980..628684
                     /locus_tag="spr0618"
                     /db_xref="GeneID:932924"
     CDS             627980..628684
                     /locus_tag="spr0618"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358212.1"
                     /db_xref="GI:15902662"
                     /db_xref="GeneID:932924"
     gene            628681..629328
                     /gene="ABC-NBD"
                     /locus_tag="spr0619"
                     /db_xref="GeneID:934873"
     CDS             628681..629328
                     /gene="ABC-NBD"
                     /locus_tag="spr0619"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358213.1"
                     /db_xref="GI:15902663"
                     /db_xref="GeneID:934873"
     gene            complement(629408..630273)
                     /gene="ABC-SBP-truncation"
                     /locus_tag="spr0620"
                     /pseudogene="unknown"
                     /db_xref="GeneID:932886"
     gene            complement(630285..631043)
                     /gene="glnQ"
                     /locus_tag="spr0622"
                     /db_xref="GeneID:934886"
     CDS             complement(630285..631043)
                     /gene="glnQ"
                     /locus_tag="spr0622"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358216.1"
                     /db_xref="GI:15902666"
                     /db_xref="GeneID:934886"
     gene            complement(631044..631721)
                     /gene="glnP"
                     /locus_tag="spr0623"
                     /db_xref="GeneID:932849"
     CDS             complement(631044..631721)
                     /gene="glnP"
                     /locus_tag="spr0623"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358217.1"
                     /db_xref="GI:15902667"
                     /db_xref="GeneID:932849"
     gene            complement(631681..632361)
                     /gene="glnP"
                     /locus_tag="spr0624"
                     /db_xref="GeneID:932908"
     CDS             complement(631681..632361)
                     /gene="glnP"
                     /locus_tag="spr0624"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358218.1"
                     /db_xref="GI:15902668"
                     /db_xref="GeneID:932908"
     gene            632850..634340
                     /gene="lysS"
                     /locus_tag="spr0626"
                     /db_xref="GeneID:932817"
     CDS             632850..634340
                     /gene="lysS"
                     /locus_tag="spr0626"
                     /EC_number="6.1.1.6"
                     /note="class II; LysRS2; catalyzes a two-step reaction,
                     first charging a lysine molecule by linking its carboxyl
                     group to the alpha-phosphate of ATP, followed by transfer
                     of the aminoacyl-adenylate to its tRNA; in Methanosarcina
                     barkeri, LysRS2 charges both tRNA molecules for lysine
                     that exist in this organism and in addition can charge the
                     tRNAPyl with lysine in the presence of LysRS1"
                     /codon_start=1
                     /transl_table=11
                     /product="lysyl-tRNA synthetase"
                     /protein_id="NP_358220.1"
                     /db_xref="GI:15902670"
                     /db_xref="GeneID:932817"
     repeat_region   634413..634519
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_c"
     gene            634965..636101
                     /gene="lctO"
                     /locus_tag="spr0627"
                     /db_xref="GeneID:932862"
     CDS             634965..636101
                     /gene="lctO"
                     /locus_tag="spr0627"
                     /EC_number="1.1.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="NP_358221.1"
                     /db_xref="GI:15902671"
                     /db_xref="GeneID:932862"
     repeat_region   complement(636174..636280)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            636656..637324
                     /locus_tag="spr0628"
                     /db_xref="GeneID:932837"
     CDS             636656..637324
                     /locus_tag="spr0628"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358222.1"
                     /db_xref="GI:15902672"
                     /db_xref="GeneID:932837"
     repeat_region   637362..637519
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            637592..638395
                     /gene="thiM"
                     /locus_tag="spr0629"
                     /db_xref="GeneID:934546"
     CDS             637592..638395
                     /gene="thiM"
                     /locus_tag="spr0629"
                     /EC_number="2.7.1.50"
                     /note="catalyzes the formation of
                     4-methyl-5-(2-phosphoethyl)-thiazole and ADP from
                     4-methyl-5-(2-hydroxyethyl)-thiazole and ATP"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="NP_358223.1"
                     /db_xref="GI:15902673"
                     /db_xref="GeneID:934546"
     gene            638397..639026
                     /gene="thiE"
                     /locus_tag="spr0630"
                     /db_xref="GeneID:932808"
     CDS             638397..639026
                     /gene="thiE"
                     /locus_tag="spr0630"
                     /EC_number="2.5.1.3"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate pyrophosphorylase"
                     /protein_id="NP_358224.1"
                     /db_xref="GI:15902674"
                     /db_xref="GeneID:932808"
     repeat_region   complement(639419..639490)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            639551..640144
                     /locus_tag="spr0631"
                     /db_xref="GeneID:934636"
     CDS             639551..640144
                     /locus_tag="spr0631"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358225.1"
                     /db_xref="GI:15902675"
                     /db_xref="GeneID:934636"
     gene            640145..641530
                     /gene="ABC-NBD"
                     /locus_tag="spr0632"
                     /db_xref="GeneID:934174"
     CDS             640145..641530
                     /gene="ABC-NBD"
                     /locus_tag="spr0632"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358226.1"
                     /db_xref="GI:15902676"
                     /db_xref="GeneID:934174"
     gene            641532..642182
                     /locus_tag="spr0633"
                     /db_xref="GeneID:934339"
     CDS             641532..642182
                     /locus_tag="spr0633"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358227.1"
                     /db_xref="GI:15902677"
                     /db_xref="GeneID:934339"
     gene            642193..642885
                     /gene="tenA"
                     /locus_tag="spr0634"
                     /db_xref="GeneID:934245"
     CDS             642193..642885
                     /gene="tenA"
                     /locus_tag="spr0634"
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular enzyme gene transcriptional
                     regulator"
                     /protein_id="NP_358228.1"
                     /db_xref="GI:15902678"
                     /db_xref="GeneID:934245"
     gene            642890..643414
                     /locus_tag="spr0635"
                     /db_xref="GeneID:934493"
     CDS             642890..643414
                     /locus_tag="spr0635"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358229.1"
                     /db_xref="GI:15902679"
                     /db_xref="GeneID:934493"
     gene            643414..644217
                     /gene="thiM"
                     /locus_tag="spr0636"
                     /db_xref="GeneID:934435"
     CDS             643414..644217
                     /gene="thiM"
                     /locus_tag="spr0636"
                     /EC_number="2.7.1.50"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="NP_358230.1"
                     /db_xref="GI:15902680"
                     /db_xref="GeneID:934435"
     gene            644210..644842
                     /gene="thiE"
                     /locus_tag="spr0637"
                     /db_xref="GeneID:934175"
     CDS             644210..644842
                     /gene="thiE"
                     /locus_tag="spr0637"
                     /EC_number="2.5.1.3"
                     /note="Condenses 4-methyl-5-(beta-hydroxyethyl)-thiazole
                     monophosphate and 4-amino-5-hydroxymethyl pyrimidine
                     pyrophosphate to form thiamine monophosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate pyrophosphorylase"
                     /protein_id="NP_358231.1"
                     /db_xref="GI:15902681"
                     /db_xref="GeneID:934175"
     repeat_region   complement(644846..645004)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(645051..645842)
                     /gene="thiD"
                     /locus_tag="spr0638"
                     /db_xref="GeneID:934176"
     CDS             complement(645051..645842)
                     /gene="thiD"
                     /locus_tag="spr0638"
                     /EC_number="2.7.4.7"
                     /note="catalyzes the formation of
                     4-amino-2-methyl-5-diphosphomethylpyrimidine"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine kinase"
                     /protein_id="NP_358232.1"
                     /db_xref="GI:15902682"
                     /db_xref="GeneID:934176"
     gene            646178..646603
                     /gene="copY"
                     /locus_tag="spr0639"
                     /db_xref="GeneID:934180"
     CDS             646178..646603
                     /gene="copY"
                     /locus_tag="spr0639"
                     /codon_start=1
                     /transl_table=11
                     /product="COPAB ATPase metal-fist type repressor"
                     /protein_id="NP_358233.1"
                     /db_xref="GI:15902683"
                     /db_xref="GeneID:934180"
     gene            646614..646985
                     /locus_tag="spr0640"
                     /db_xref="GeneID:934190"
     CDS             646614..646985
                     /locus_tag="spr0640"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358234.1"
                     /db_xref="GI:15902684"
                     /db_xref="GeneID:934190"
     gene            646986..649238
                     /gene="ctpA"
                     /locus_tag="spr0641"
                     /db_xref="GeneID:934178"
     CDS             646986..649238
                     /gene="ctpA"
                     /locus_tag="spr0641"
                     /EC_number="3.6.3.10"
                     /codon_start=1
                     /transl_table=11
                     /product="copper transporter P-type ATPase"
                     /protein_id="NP_358235.1"
                     /db_xref="GI:15902685"
                     /db_xref="GeneID:934178"
     gene            649445..651220
                     /gene="spxB"
                     /locus_tag="spr0642"
                     /db_xref="GeneID:934181"
     CDS             649445..651220
                     /gene="spxB"
                     /locus_tag="spr0642"
                     /EC_number="1.2.3.3"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="NP_358236.1"
                     /db_xref="GI:15902686"
                     /db_xref="GeneID:934181"
     gene            651331..651678
                     /locus_tag="spr0643"
                     /db_xref="GeneID:934177"
     CDS             651331..651678
                     /locus_tag="spr0643"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358237.1"
                     /db_xref="GI:15902687"
                     /db_xref="GeneID:934177"
     gene            complement(651795..652448)
                     /gene="transposase_C"
                     /locus_tag="spr0644"
                     /db_xref="GeneID:934179"
     CDS             complement(651795..652448)
                     /gene="transposase_C"
                     /locus_tag="spr0644"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358238.1"
                     /db_xref="GI:15902688"
                     /db_xref="GeneID:934179"
     gene            complement(652336..652683)
                     /locus_tag="spr0645"
                     /db_xref="GeneID:934183"
     CDS             complement(652336..652683)
                     /locus_tag="spr0645"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358239.1"
                     /db_xref="GI:15902689"
                     /db_xref="GeneID:934183"
     repeat_region   652704..652810
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     repeat_region   652861..652960
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            653533..654477
                     /gene="pmi"
                     /locus_tag="spr0647"
                     /db_xref="GeneID:934184"
     CDS             653533..654477
                     /gene="pmi"
                     /locus_tag="spr0647"
                     /EC_number="5.3.1.8"
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="NP_358241.1"
                     /db_xref="GI:15902691"
                     /db_xref="GeneID:934184"
     gene            complement(654580..655971)
                     /gene="NS_transporter"
                     /locus_tag="spr0648"
                     /db_xref="GeneID:934182"
     CDS             complement(654580..655971)
                     /gene="NS_transporter"
                     /locus_tag="spr0648"
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
                     /protein_id="NP_358242.1"
                     /db_xref="GI:15902692"
                     /db_xref="GeneID:934182"
     gene            656131..656793
                     /gene="mta"
                     /locus_tag="spr0649"
                     /db_xref="GeneID:934189"
     CDS             656131..656793
                     /gene="mta"
                     /locus_tag="spr0649"
                     /codon_start=1
                     /transl_table=11
                     /product="regulator of the multidrug efflux pump pmrA"
                     /protein_id="NP_358243.1"
                     /db_xref="GI:15902693"
                     /db_xref="GeneID:934189"
     gene            complement(656822..657277)
                     /locus_tag="spr0650"
                     /db_xref="GeneID:934185"
     CDS             complement(656822..657277)
                     /locus_tag="spr0650"
                     /note="Similar to mutator protein MutT"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358244.1"
                     /db_xref="GI:15902694"
                     /db_xref="GeneID:934185"
     gene            complement(657297..658490)
                     /locus_tag="spr0651"
                     /db_xref="GeneID:934187"
     CDS             complement(657297..658490)
                     /locus_tag="spr0651"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358245.1"
                     /db_xref="GI:15902695"
                     /db_xref="GeneID:934187"
     gene            complement(658531..659376)
                     /locus_tag="spr0652"
                     /db_xref="GeneID:934192"
     CDS             complement(658531..659376)
                     /locus_tag="spr0652"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358246.1"
                     /db_xref="GI:15902696"
                     /db_xref="GeneID:934192"
     gene            659501..660058
                     /locus_tag="spr0653"
                     /db_xref="GeneID:934188"
     CDS             659501..660058
                     /locus_tag="spr0653"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358247.1"
                     /db_xref="GI:15902697"
                     /db_xref="GeneID:934188"
     gene            660077..660544
                     /gene="comEB"
                     /locus_tag="spr0654"
                     /db_xref="GeneID:934191"
     CDS             660077..660544
                     /gene="comEB"
                     /locus_tag="spr0654"
                     /EC_number="3.5.4.5"
                     /note="late competence operon required for DNA binding and
                     uptake"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine and deoxycytidylate deaminase"
                     /protein_id="NP_358248.1"
                     /db_xref="GI:15902698"
                     /db_xref="GeneID:934191"
     gene            660612..661262
                     /gene="upp"
                     /locus_tag="spr0655"
                     /db_xref="GeneID:934196"
     CDS             660612..661262
                     /gene="upp"
                     /locus_tag="spr0655"
                     /EC_number="2.4.2.9"
                     /note="Catalyzes the formation of uracil and
                     5-phospho-alpha-D-ribosy 1-diphosphate from UMP and
                     diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="NP_358249.1"
                     /db_xref="GI:15902699"
                     /db_xref="GeneID:934196"
     gene            661436..662026
                     /gene="clpP"
                     /locus_tag="spr0656"
                     /db_xref="GeneID:934194"
     CDS             661436..662026
                     /gene="clpP"
                     /locus_tag="spr0656"
                     /EC_number="3.4.21.92"
                     /note="hydrolyzes proteins to small peptides; with the
                     ATPase subunits ClpA or ClpX, ClpP degrades specific
                     substrates"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit"
                     /protein_id="NP_358250.1"
                     /db_xref="GI:15902700"
                     /db_xref="GeneID:934194"
     gene            662105..662353
                     /locus_tag="spr0657"
                     /db_xref="GeneID:934193"
     CDS             662105..662353
                     /locus_tag="spr0657"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358251.1"
                     /db_xref="GI:15902701"
                     /db_xref="GeneID:934193"
     gene            complement(662219..662449)
                     /locus_tag="spr0658"
                     /db_xref="GeneID:934197"
     CDS             complement(662219..662449)
                     /locus_tag="spr0658"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358252.1"
                     /db_xref="GI:15902702"
                     /db_xref="GeneID:934197"
     gene            662455..663615
                     /gene="livJ"
                     /locus_tag="spr0659"
                     /db_xref="GeneID:934202"
     CDS             662455..663615
                     /gene="livJ"
                     /locus_tag="spr0659"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate+B481-binding protein"
                     /protein_id="NP_358253.1"
                     /db_xref="GI:15902703"
                     /db_xref="GeneID:934202"
     repeat_region   663670..663823
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            663874..664752
                     /gene="livH"
                     /locus_tag="spr0660"
                     /db_xref="GeneID:934200"
     CDS             663874..664752
                     /gene="livH"
                     /locus_tag="spr0660"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease"
                     /protein_id="NP_358254.1"
                     /db_xref="GI:15902704"
                     /db_xref="GeneID:934200"
     gene            664756..665712
                     /gene="livM"
                     /locus_tag="spr0661"
                     /db_xref="GeneID:934195"
     CDS             664756..665712
                     /gene="livM"
                     /locus_tag="spr0661"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease"
                     /protein_id="NP_358255.1"
                     /db_xref="GI:15902705"
                     /db_xref="GeneID:934195"
     gene            665712..666476
                     /gene="livG"
                     /locus_tag="spr0662"
                     /db_xref="GeneID:934198"
     CDS             665712..666476
                     /gene="livG"
                     /locus_tag="spr0662"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     ATP-binding protein"
                     /protein_id="NP_358256.1"
                     /db_xref="GI:15902706"
                     /db_xref="GeneID:934198"
     gene            666476..667186
                     /gene="livF"
                     /locus_tag="spr0663"
                     /db_xref="GeneID:934205"
     CDS             666476..667186
                     /gene="livF"
                     /locus_tag="spr0663"
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     ATP-binding protein"
                     /protein_id="NP_358257.1"
                     /db_xref="GI:15902707"
                     /db_xref="GeneID:934205"
     gene            667600..668256
                     /locus_tag="spr0664"
                     /db_xref="GeneID:934199"
     CDS             667600..668256
                     /locus_tag="spr0664"
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin utilization protein AcuB"
                     /protein_id="NP_358258.1"
                     /db_xref="GI:15902708"
                     /db_xref="GeneID:934199"
     gene            668470..669459
                     /gene="prfB"
                     /locus_tag="spr0665"
                     /db_xref="GeneID:934204"
     CDS             668470..669459
                     /gene="prfB"
                     /locus_tag="spr0665"
                     /note="recognizes the termination signals UGA and UAA
                     during protein translation a specificity which is
                     dependent on amino acid residues residing in loops of the
                     L-shaped tRNA-like molecule of RF2; in some organisms
                     control of PrfB protein levels is maintained through a +1
                     ribosomal frameshifting mechanism; this protein is similar
                     to release factor 1"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="NP_358259.1"
                     /db_xref="GI:15902709"
                     /db_xref="GeneID:934204"
     gene            669477..670169
                     /gene="ftsE"
                     /locus_tag="spr0666"
                     /db_xref="GeneID:934207"
     CDS             669477..670169
                     /gene="ftsE"
                     /locus_tag="spr0666"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358260.1"
                     /db_xref="GI:15902710"
                     /db_xref="GeneID:934207"
     gene            670099..671088
                     /gene="ftsX"
                     /locus_tag="spr0667"
                     /db_xref="GeneID:934201"
     CDS             670099..671088
                     /gene="ftsX"
                     /locus_tag="spr0667"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ABC transporter permease FtsX"
                     /protein_id="NP_358261.1"
                     /db_xref="GI:15902711"
                     /db_xref="GeneID:934201"
     gene            671374..673554
                     /gene="ptsG"
                     /locus_tag="spr0668"
                     /db_xref="GeneID:934203"
     CDS             671374..673554
                     /gene="ptsG"
                     /locus_tag="spr0668"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIABC"
                     /protein_id="NP_358262.1"
                     /db_xref="GI:15902712"
                     /db_xref="GeneID:934203"
     gene            673606..674421
                     /locus_tag="spr0669"
                     /db_xref="GeneID:934209"
     CDS             673606..674421
                     /locus_tag="spr0669"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358263.1"
                     /db_xref="GI:15902713"
                     /db_xref="GeneID:934209"
     gene            674561..675904
                     /gene="rheB"
                     /locus_tag="spr0670"
                     /db_xref="GeneID:934208"
     CDS             674561..675904
                     /gene="rheB"
                     /locus_tag="spr0670"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase"
                     /protein_id="NP_358264.1"
                     /db_xref="GI:15902714"
                     /db_xref="GeneID:934208"
     gene            676119..677309
                     /gene="metK"
                     /locus_tag="spr0671"
                     /db_xref="GeneID:934206"
     CDS             676119..677309
                     /gene="metK"
                     /locus_tag="spr0671"
                     /EC_number="2.5.1.6"
                     /note="methionine adenosyltransferase; catalyzes the
                     formation of S-adenosylmethionine from methionine and ATP;
                     methionine adenosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine synthetase"
                     /protein_id="NP_358265.1"
                     /db_xref="GI:15902715"
                     /db_xref="GeneID:934206"
     repeat_region   677405..677511
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            677862..678797
                     /gene="pyrDA"
                     /locus_tag="spr0672"
                     /db_xref="GeneID:934210"
     CDS             677862..678797
                     /gene="pyrDA"
                     /locus_tag="spr0672"
                     /note="catalyzes the conversion of dihydroorotate to
                     orotate in the pyrimidine biosynthesis pathway; subclass
                     1A is a dimer formed by two identical PyrD subunits each
                     containing an FMN group"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase 1A"
                     /protein_id="NP_358266.1"
                     /db_xref="GI:15902716"
                     /db_xref="GeneID:934210"
     gene            678831..679868
                     /gene="holA"
                     /locus_tag="spr0673"
                     /db_xref="GeneID:934219"
     CDS             678831..679868
                     /gene="holA"
                     /locus_tag="spr0673"
                     /note="required for the assembly and function of the DNAX
                     complex which is required for the assembly of the beta
                     subunit onto primed DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="NP_358267.1"
                     /db_xref="GI:15902717"
                     /db_xref="GeneID:934219"
     gene            680041..680646
                     /gene="sodA"
                     /locus_tag="spr0674"
                     /db_xref="GeneID:934215"
     CDS             680041..680646
                     /gene="sodA"
                     /locus_tag="spr0674"
                     /EC_number="1.15.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="NP_358268.1"
                     /db_xref="GI:15902718"
                     /db_xref="GeneID:934215"
     gene            680803..681333
                     /locus_tag="spr0675"
                     /db_xref="GeneID:934214"
     CDS             680803..681333
                     /locus_tag="spr0675"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358269.1"
                     /db_xref="GI:15902719"
                     /db_xref="GeneID:934214"
     gene            681354..682439
                     /locus_tag="spr0676"
                     /db_xref="GeneID:934211"
     CDS             681354..682439
                     /locus_tag="spr0676"
                     /note="23S rRNA m2A2503 methyltransferase; methylates the
                     C2 position of the A2530 nucleotide in 23S rRNA; may be
                     involved in antibiotic resistance"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal RNA large subunit methyltransferase N"
                     /protein_id="NP_358270.1"
                     /db_xref="GI:15902720"
                     /db_xref="GeneID:934211"
     gene            682441..682908
                     /locus_tag="spr0677"
                     /db_xref="GeneID:934218"
     CDS             682441..682908
                     /locus_tag="spr0677"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358271.1"
                     /db_xref="GI:15902721"
                     /db_xref="GeneID:934218"
     gene            682910..684451
                     /gene="ABC-NBD"
                     /locus_tag="spr0678"
                     /db_xref="GeneID:934213"
     CDS             682910..684451
                     /gene="ABC-NBD"
                     /locus_tag="spr0678"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358272.1"
                     /db_xref="GI:15902722"
                     /db_xref="GeneID:934213"
     gene            complement(684508..685311)
                     /gene="ppiA"
                     /locus_tag="spr0679"
                     /db_xref="GeneID:934212"
     CDS             complement(684508..685311)
                     /gene="ppiA"
                     /locus_tag="spr0679"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="NP_358273.1"
                     /db_xref="GI:15902723"
                     /db_xref="GeneID:934212"
     gene            complement(685395..685616)
                     /locus_tag="spr0680"
                     /db_xref="GeneID:934228"
     CDS             complement(685395..685616)
                     /locus_tag="spr0680"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358274.1"
                     /db_xref="GI:15902724"
                     /db_xref="GeneID:934228"
     gene            complement(685504..685734)
                     /locus_tag="spr0681"
                     /db_xref="GeneID:934216"
     CDS             complement(685504..685734)
                     /locus_tag="spr0681"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358275.1"
                     /db_xref="GI:15902725"
                     /db_xref="GeneID:934216"
     gene            686482..686754
                     /gene="rpsP"
                     /locus_tag="spr0682"
                     /db_xref="GeneID:934220"
     CDS             686482..686754
                     /gene="rpsP"
                     /locus_tag="spr0682"
                     /note="binds to lower part of 30S body where it stabilizes
                     two domains; required for efficient assembly of 30S; in
                     Escherichia coli this protein has nuclease activity"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="NP_358276.1"
                     /db_xref="GI:15902726"
                     /db_xref="GeneID:934220"
     gene            686774..687013
                     /locus_tag="spr0683"
                     /db_xref="GeneID:934222"
     CDS             686774..687013
                     /locus_tag="spr0683"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358277.1"
                     /db_xref="GI:15902727"
                     /db_xref="GeneID:934222"
     repeat_region   complement(687057..687163)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            687590..688304
                     /locus_tag="spr0684"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934217"
     gene            688409..688927
                     /gene="rimM"
                     /locus_tag="spr0686"
                     /db_xref="GeneID:934224"
     CDS             688409..688927
                     /gene="rimM"
                     /locus_tag="spr0686"
                     /note="Essential for efficient processing of 16S rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA-processing protein RimM"
                     /protein_id="NP_358280.1"
                     /db_xref="GI:15902730"
                     /db_xref="GeneID:934224"
     gene            688917..689636
                     /gene="trmD"
                     /locus_tag="spr0687"
                     /db_xref="GeneID:934221"
     CDS             688917..689636
                     /gene="trmD"
                     /locus_tag="spr0687"
                     /note="methylates guanosine-37 in various tRNAs; uses
                     S-adenosyl-L-methionine to transfer methyl group to tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanine-N(1)-)-methyltransferase"
                     /protein_id="NP_358281.1"
                     /db_xref="GI:15902731"
                     /db_xref="GeneID:934221"
     gene            689648..689986
                     /locus_tag="spr0688"
                     /db_xref="GeneID:934227"
     CDS             689648..689986
                     /locus_tag="spr0688"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358282.1"
                     /db_xref="GI:15902732"
                     /db_xref="GeneID:934227"
     gene            complement(690017..690337)
                     /locus_tag="spr0689"
                     /db_xref="GeneID:934226"
     CDS             complement(690017..690337)
                     /locus_tag="spr0689"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358283.1"
                     /db_xref="GI:15902733"
                     /db_xref="GeneID:934226"
     gene            690411..690650
                     /locus_tag="spr0690"
                     /db_xref="GeneID:934225"
     CDS             690411..690650
                     /locus_tag="spr0690"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358284.1"
                     /db_xref="GI:15902734"
                     /db_xref="GeneID:934225"
     repeat_region   690647..690801
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(690854..691390)
                     /gene="bioY"
                     /locus_tag="spr0691"
                     /db_xref="GeneID:934230"
     CDS             complement(690854..691390)
                     /gene="bioY"
                     /locus_tag="spr0691"
                     /EC_number="2.8.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase"
                     /protein_id="NP_358285.1"
                     /db_xref="GI:15902735"
                     /db_xref="GeneID:934230"
     gene            complement(691587..692933)
                     /gene="gor"
                     /locus_tag="spr0692"
                     /db_xref="GeneID:934234"
     CDS             complement(691587..692933)
                     /gene="gor"
                     /locus_tag="spr0692"
                     /EC_number="1.8.1.7"
                     /note="catalyzes the reduction of 2 glutathione to
                     glutathione disulfide; maintains high levels of reduced
                     glutathione in the cytosol; involved in redox regulation
                     and oxidative defense"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione reductase"
                     /protein_id="NP_358286.1"
                     /db_xref="GI:15902736"
                     /db_xref="GeneID:934234"
     gene            693198..694397
                     /locus_tag="spr0693"
                     /db_xref="GeneID:934233"
     CDS             693198..694397
                     /locus_tag="spr0693"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358287.1"
                     /db_xref="GI:15902737"
                     /db_xref="GeneID:934233"
     gene            694381..695082
                     /gene="ABC-NBD"
                     /locus_tag="spr0694"
                     /db_xref="GeneID:934229"
     CDS             694381..695082
                     /gene="ABC-NBD"
                     /locus_tag="spr0694"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358288.1"
                     /db_xref="GI:15902738"
                     /db_xref="GeneID:934229"
     gene            695084..696343
                     /locus_tag="spr0695"
                     /db_xref="GeneID:934232"
     CDS             695084..696343
                     /locus_tag="spr0695"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358289.1"
                     /db_xref="GI:15902739"
                     /db_xref="GeneID:934232"
     gene            696467..698464
                     /gene="metG"
                     /locus_tag="spr0696"
                     /db_xref="GeneID:934240"
     CDS             696467..698464
                     /gene="metG"
                     /locus_tag="spr0696"
                     /EC_number="6.1.1.10"
                     /note="methionine--tRNA ligase; MetRS; adds methionine to
                     tRNA(Met) with cleavage of ATP to AMP and diphosphate;
                     some MetRS enzymes form dimers depending on a C-terminal
                     domain that is also found in other proteins such as
                     Trbp111 in Aquifex aeolicus and the cold-shock protein
                     CsaA from Bacillus subtilis while others do not; four
                     subfamilies exist based on sequence motifs and zinc
                     content"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA synthetase"
                     /protein_id="NP_358290.2"
                     /db_xref="GI:161410751"
                     /db_xref="GeneID:934240"
     repeat_region   complement(698504..698703)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            698514..698705
                     /locus_tag="spr0696a"
                     /db_xref="GeneID:17374506"
     CDS             698514..698705
                     /locus_tag="spr0696a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719801.1"
                     /db_xref="GI:555247347"
                     /db_xref="GeneID:17374506"
     gene            698792..699115
                     /locus_tag="spr0697"
                     /db_xref="GeneID:934231"
     CDS             698792..699115
                     /locus_tag="spr0697"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358291.1"
                     /db_xref="GI:15902741"
                     /db_xref="GeneID:934231"
     gene            699119..699994
                     /locus_tag="spr0698"
                     /db_xref="GeneID:934238"
     CDS             699119..699994
                     /locus_tag="spr0698"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358292.1"
                     /db_xref="GI:15902742"
                     /db_xref="GeneID:934238"
     gene            700006..700935
                     /locus_tag="spr0699"
                     /db_xref="GeneID:934236"
     CDS             700006..700935
                     /locus_tag="spr0699"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358293.1"
                     /db_xref="GI:15902743"
                     /db_xref="GeneID:934236"
     gene            701014..701271
                     /locus_tag="spr0700"
                     /db_xref="GeneID:934235"
     CDS             701014..701271
                     /locus_tag="spr0700"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358294.1"
                     /db_xref="GI:15902744"
                     /db_xref="GeneID:934235"
     gene            701264..701962
                     /gene="fabG"
                     /locus_tag="spr0701"
                     /db_xref="GeneID:934242"
     CDS             701264..701962
                     /gene="fabG"
                     /locus_tag="spr0701"
                     /EC_number="1.1.1.100"
                     /note="Catalyzes the first of the two reduction steps in
                     the elongation cycle of fatty acid synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="NP_358295.1"
                     /db_xref="GI:15902745"
                     /db_xref="GeneID:934242"
     gene            701973..702452
                     /locus_tag="spr0702"
                     /db_xref="GeneID:934237"
     CDS             701973..702452
                     /locus_tag="spr0702"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="NP_358296.1"
                     /db_xref="GI:15902746"
                     /db_xref="GeneID:934237"
     gene            702460..703188
                     /locus_tag="spr0703"
                     /db_xref="GeneID:934250"
     CDS             702460..703188
                     /locus_tag="spr0703"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358297.1"
                     /db_xref="GI:15902747"
                     /db_xref="GeneID:934250"
     gene            703224..704099
                     /locus_tag="spr0704"
                     /db_xref="GeneID:934243"
     CDS             703224..704099
                     /locus_tag="spr0704"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358298.1"
                     /db_xref="GI:15902748"
                     /db_xref="GeneID:934243"
     gene            704074..704514
                     /locus_tag="spr0705"
                     /db_xref="GeneID:934239"
     CDS             704074..704514
                     /locus_tag="spr0705"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358299.1"
                     /db_xref="GI:15902749"
                     /db_xref="GeneID:934239"
     gene            704637..707183
                     /gene="pepN"
                     /locus_tag="spr0706"
                     /db_xref="GeneID:934241"
     CDS             704637..707183
                     /gene="pepN"
                     /locus_tag="spr0706"
                     /EC_number="3.4.11.2"
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="NP_358300.1"
                     /db_xref="GI:15902750"
                     /db_xref="GeneID:934241"
     gene            707226..707966
                     /gene="ciaR"
                     /locus_tag="spr0707"
                     /db_xref="GeneID:934251"
     CDS             707226..707966
                     /gene="ciaR"
                     /locus_tag="spr0707"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator CiaR"
                     /protein_id="NP_358301.1"
                     /db_xref="GI:15902751"
                     /db_xref="GeneID:934251"
     gene            707956..709290
                     /gene="ciaH"
                     /locus_tag="spr0708"
                     /db_xref="GeneID:934244"
     CDS             707956..709290
                     /gene="ciaH"
                     /locus_tag="spr0708"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase CiaH"
                     /protein_id="NP_358302.1"
                     /db_xref="GI:15902752"
                     /db_xref="GeneID:934244"
     gene            complement(709324..709611)
                     /locus_tag="spr0709"
                     /db_xref="GeneID:934248"
     CDS             complement(709324..709611)
                     /locus_tag="spr0709"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358303.1"
                     /db_xref="GI:15902753"
                     /db_xref="GeneID:934248"
     gene            709610..710680
                     /locus_tag="spr0710"
                     /db_xref="GeneID:934270"
     CDS             709610..710680
                     /locus_tag="spr0710"
                     /note="Similar to protease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358304.1"
                     /db_xref="GI:15902754"
                     /db_xref="GeneID:934270"
     gene            710880..713330
                     /gene="dinG"
                     /locus_tag="spr0711"
                     /db_xref="GeneID:934246"
     CDS             710880..713330
                     /gene="dinG"
                     /locus_tag="spr0711"
                     /note="unwinds DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ATP-dependent DNA helicase/DNA
                     polymerase III subunit epsilon"
                     /protein_id="NP_358305.1"
                     /db_xref="GI:15902755"
                     /db_xref="GeneID:934246"
     gene            713340..714590
                     /gene="rodA"
                     /locus_tag="spr0712"
                     /db_xref="GeneID:934247"
     CDS             713340..714590
                     /gene="rodA"
                     /locus_tag="spr0712"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein RodA"
                     /protein_id="NP_358306.1"
                     /db_xref="GI:15902756"
                     /db_xref="GeneID:934247"
     gene            714601..715155
                     /gene="thiJ"
                     /locus_tag="spr0713"
                     /db_xref="GeneID:934252"
     CDS             714601..715155
                     /gene="thiJ"
                     /locus_tag="spr0713"
                     /codon_start=1
                     /transl_table=11
                     /product="4-methyl-5(b-hydroxyethyl)-thiazole
                     monophosphate biosynthesis protein"
                     /protein_id="NP_358307.1"
                     /db_xref="GI:15902757"
                     /db_xref="GeneID:934252"
     gene            715231..715803
                     /gene="gph"
                     /locus_tag="spr0714"
                     /db_xref="GeneID:934249"
     CDS             715231..715803
                     /gene="gph"
                     /locus_tag="spr0714"
                     /EC_number="3.1.3.18"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="NP_358308.1"
                     /db_xref="GI:15902758"
                     /db_xref="GeneID:934249"
     gene            715818..717764
                     /gene="gyrB"
                     /locus_tag="spr0715"
                     /db_xref="GeneID:934253"
     CDS             715818..717764
                     /gene="gyrB"
                     /locus_tag="spr0715"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit B"
                     /protein_id="NP_358309.1"
                     /db_xref="GI:15902759"
                     /db_xref="GeneID:934253"
     gene            717819..719573
                     /gene="ezrA"
                     /locus_tag="spr0716"
                     /db_xref="GeneID:934258"
     CDS             717819..719573
                     /gene="ezrA"
                     /locus_tag="spr0716"
                     /note="acts to negatively regulates ftsZ ring formation by
                     modulating the frequency and position of the ftsZ ring
                     formation"
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="NP_358310.1"
                     /db_xref="GI:15902760"
                     /db_xref="GeneID:934258"
     repeat_region   719707..719810
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     repeat_region   complement(720199..720297)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            720316..720720
                     /gene="transposase_C"
                     /locus_tag="spr0717"
                     /db_xref="GeneID:934257"
     CDS             720316..720720
                     /gene="transposase_C"
                     /locus_tag="spr0717"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358311.1"
                     /db_xref="GI:15902761"
                     /db_xref="GeneID:934257"
     gene            720608..721261
                     /gene="transposase_D"
                     /locus_tag="spr0718"
                     /db_xref="GeneID:934256"
     CDS             720608..721261
                     /gene="transposase_D"
                     /locus_tag="spr0718"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358312.1"
                     /db_xref="GI:15902762"
                     /db_xref="GeneID:934256"
     gene            complement(721347..721634)
                     /gene="transposase_E"
                     /locus_tag="spr0719"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934255"
     gene            complement(721895..722194)
                     /locus_tag="spr0720"
                     /db_xref="GeneID:934259"
     CDS             complement(721895..722194)
                     /locus_tag="spr0720"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358314.1"
                     /db_xref="GI:15902764"
                     /db_xref="GeneID:934259"
     repeat_region   complement(722252..722360)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(722359..722781)
                     /locus_tag="spr0721"
                     /db_xref="GeneID:934254"
     CDS             complement(722359..722781)
                     /locus_tag="spr0721"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="NP_358315.1"
                     /db_xref="GI:15902765"
                     /db_xref="GeneID:934254"
     gene            722874..723221
                     /gene="transposase_A"
                     /locus_tag="spr0722"
                     /db_xref="GeneID:934263"
     CDS             722874..723221
                     /gene="transposase_A"
                     /locus_tag="spr0722"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358316.1"
                     /db_xref="GI:15902766"
                     /db_xref="GeneID:934263"
     repeat_region   complement(723740..723846)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     gene            complement(723946..726204)
                     /gene="clpE"
                     /locus_tag="spr0725"
                     /db_xref="GeneID:934262"
     CDS             complement(723946..726204)
                     /gene="clpE"
                     /locus_tag="spr0725"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP dependent protease"
                     /protein_id="NP_358319.1"
                     /db_xref="GI:15902769"
                     /db_xref="GeneID:934262"
     gene            complement(726433..726663)
                     /locus_tag="spr0726"
                     /db_xref="GeneID:934264"
     CDS             complement(726433..726663)
                     /locus_tag="spr0726"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358320.1"
                     /db_xref="GI:15902770"
                     /db_xref="GeneID:934264"
     gene            726847..727536
                     /gene="glnP"
                     /locus_tag="spr0727"
                     /db_xref="GeneID:934267"
     CDS             726847..727536
                     /gene="glnP"
                     /locus_tag="spr0727"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358321.1"
                     /db_xref="GI:15902771"
                     /db_xref="GeneID:934267"
     gene            727536..728270
                     /gene="glnQ"
                     /locus_tag="spr0728"
                     /db_xref="GeneID:934265"
     CDS             727536..728270
                     /gene="glnQ"
                     /locus_tag="spr0728"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358322.1"
                     /db_xref="GI:15902772"
                     /db_xref="GeneID:934265"
     gene            728361..729281
                     /gene="folD"
                     /locus_tag="spr0729"
                     /db_xref="GeneID:934266"
     CDS             728361..729281
                     /gene="folD"
                     /locus_tag="spr0729"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /note="catalyzes the formation of
                     5,10-methenyltetrahydrofolate from
                     5,10-methylenetetrahydrofolate and subsequent formation of
                     10-formyltetrahydrofolate from
                     5,10-methenyltetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 5,10-methylene-tetrahydrofolate
                     dehydrogenase/ 5,10-methylene-tetrahydrofolate
                     cyclohydrolase"
                     /protein_id="NP_358323.1"
                     /db_xref="GI:15902773"
                     /db_xref="GeneID:934266"
     gene            729423..730295
                     /locus_tag="spr0730"
                     /db_xref="GeneID:934273"
     CDS             729423..730295
                     /locus_tag="spr0730"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358324.1"
                     /db_xref="GI:15902774"
                     /db_xref="GeneID:934273"
     gene            730520..731260
                     /gene="rpiA"
                     /locus_tag="spr0731"
                     /db_xref="GeneID:934268"
     CDS             730520..731260
                     /gene="rpiA"
                     /locus_tag="spr0731"
                     /EC_number="5.3.1.6"
                     /note="Catalyzes D-ribose 5-phosphate --> D-ribulose
                     5-phosphate in the nonoxidative branch of the pentose
                     phosphate pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase A"
                     /protein_id="NP_358325.1"
                     /db_xref="GI:15902775"
                     /db_xref="GeneID:934268"
     gene            731211..732485
                     /gene="deoB"
                     /locus_tag="spr0732"
                     /db_xref="GeneID:934269"
     CDS             731211..732485
                     /gene="deoB"
                     /locus_tag="spr0732"
                     /EC_number="5.4.2.7"
                     /note="catalyzes the transfer of phosphate between the C1
                     and C5 carbons of pentose"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="NP_358326.1"
                     /db_xref="GI:15902776"
                     /db_xref="GeneID:934269"
     gene            732487..733029
                     /locus_tag="spr0733"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934272"
     gene            733045..733854
                     /gene="pnp"
                     /locus_tag="spr0734"
                     /db_xref="GeneID:934285"
     CDS             733045..733854
                     /gene="pnp"
                     /locus_tag="spr0734"
                     /EC_number="2.4.2.1"
                     /note="catalyzes the formation of a purine and ribose
                     phosphate from a purine nucleoside; in E. coli this enzyme
                     functions in xanthosine degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase"
                     /protein_id="NP_358328.1"
                     /db_xref="GI:15902778"
                     /db_xref="GeneID:934285"
     gene            734330..735310
                     /locus_tag="spr0735"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934275"
     gene            735335..735847
                     /locus_tag="spr0737"
                     /db_xref="GeneID:934271"
     CDS             735335..735847
                     /locus_tag="spr0737"
                     /note="Related to a cytolysin"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin-like protein"
                     /protein_id="NP_358331.1"
                     /db_xref="GI:15902781"
                     /db_xref="GeneID:934271"
     repeat_region   complement(735945..736094)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            736505..737215
                     /gene="deoD"
                     /locus_tag="spr0738"
                     /db_xref="GeneID:934280"
     CDS             736505..737215
                     /gene="deoD"
                     /locus_tag="spr0738"
                     /EC_number="2.4.2.1"
                     /note="catalyzes the reversible phosphorolysis of
                     ribonucleosides and 2'- deoxyribonucleosides to the free
                     base and (2'-deoxy)ribose-1- phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphorylase"
                     /protein_id="NP_358332.1"
                     /db_xref="GI:15902782"
                     /db_xref="GeneID:934280"
     gene            complement(737238..737762)
                     /gene="flaR"
                     /locus_tag="spr0739"
                     /db_xref="GeneID:934274"
     CDS             complement(737238..737762)
                     /gene="flaR"
                     /locus_tag="spr0739"
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="NP_358333.1"
                     /db_xref="GI:15902783"
                     /db_xref="GeneID:934274"
     gene            complement(737815..738051)
                     /gene="rpsT"
                     /locus_tag="spr0740"
                     /db_xref="GeneID:934276"
     CDS             complement(737815..738051)
                     /gene="rpsT"
                     /locus_tag="spr0740"
                     /note="binds directly to the 16S rRNA and is involved in
                     post-translational inhibition of arginine and ornithine
                     decarboxylase"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="NP_358334.2"
                     /db_xref="GI:161410750"
                     /db_xref="GeneID:934276"
     gene            complement(738119..739069)
                     /gene="coaA"
                     /locus_tag="spr0741"
                     /db_xref="GeneID:934284"
     CDS             complement(738119..739069)
                     /gene="coaA"
                     /locus_tag="spr0741"
                     /EC_number="2.7.1.33"
                     /note="catalyzes the formation of
                     (R)-4'-phosphopantothenate in coenzyme A biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="pantothenate kinase"
                     /protein_id="NP_358335.1"
                     /db_xref="GI:15902785"
                     /db_xref="GeneID:934284"
     gene            739237..739677
                     /locus_tag="spr0742"
                     /db_xref="GeneID:934278"
     CDS             739237..739677
                     /locus_tag="spr0742"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358336.1"
                     /db_xref="GI:15902786"
                     /db_xref="GeneID:934278"
     gene            739884..740474
                     /locus_tag="spr0743"
                     /db_xref="GeneID:934279"
     CDS             739884..740474
                     /locus_tag="spr0743"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358337.1"
                     /db_xref="GI:15902787"
                     /db_xref="GeneID:934279"
     gene            740471..741748
                     /gene="pdp"
                     /locus_tag="spr0744"
                     /db_xref="GeneID:934286"
     CDS             740471..741748
                     /gene="pdp"
                     /locus_tag="spr0744"
                     /EC_number="2.4.2.2"
                     /note="Catalyzes the reversible phosphorolysis of
                     pyrimidines in the nucleotide synthesis salvage pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="NP_358338.1"
                     /db_xref="GI:15902788"
                     /db_xref="GeneID:934286"
     gene            741766..742428
                     /gene="deoC"
                     /locus_tag="spr0745"
                     /db_xref="GeneID:934282"
     CDS             741766..742428
                     /gene="deoC"
                     /locus_tag="spr0745"
                     /EC_number="4.1.2.4"
                     /note="catalyzes the formation of D-glyceraldehyde
                     3-phosphate and acetaldehyde from
                     2-deoxy-D-ribose-5-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="NP_358339.1"
                     /db_xref="GI:15902789"
                     /db_xref="GeneID:934282"
     gene            742415..742804
                     /gene="cdd"
                     /locus_tag="spr0746"
                     /db_xref="GeneID:934281"
     CDS             742415..742804
                     /gene="cdd"
                     /locus_tag="spr0746"
                     /EC_number="3.5.4.5"
                     /note="Reclaims exogenous and endogenous cytidine and
                     2'-deoxycytidine molecules for UMP synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="NP_358340.1"
                     /db_xref="GI:15902790"
                     /db_xref="GeneID:934281"
     gene            742822..743946
                     /locus_tag="spr0747"
                     /db_xref="GeneID:934288"
     CDS             742822..743946
                     /locus_tag="spr0747"
                     /note="Similar to basic membrane protein A from
                     Lactococcus lactis subsp. lactis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358341.1"
                     /db_xref="GI:15902791"
                     /db_xref="GeneID:934288"
     gene            744090..745625
                     /gene="ABC-NBD"
                     /locus_tag="spr0748"
                     /db_xref="GeneID:934283"
     CDS             744090..745625
                     /gene="ABC-NBD"
                     /locus_tag="spr0748"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="NP_358342.1"
                     /db_xref="GI:15902792"
                     /db_xref="GeneID:934283"
     gene            745591..746676
                     /gene="ABC-MSP"
                     /locus_tag="spr0749"
                     /db_xref="GeneID:934289"
     CDS             745591..746676
                     /gene="ABC-MSP"
                     /locus_tag="spr0749"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_358343.1"
                     /db_xref="GI:15902793"
                     /db_xref="GeneID:934289"
     gene            746679..747635
                     /gene="ABC-MSP"
                     /locus_tag="spr0750"
                     /db_xref="GeneID:934291"
     CDS             746679..747635
                     /gene="ABC-MSP"
                     /locus_tag="spr0750"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_358344.1"
                     /db_xref="GI:15902794"
                     /db_xref="GeneID:934291"
     gene            747720..748235
                     /gene="IS861-truncation"
                     /locus_tag="spr0751"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934294"
     gene            748235..749067
                     /gene="IS861-truncation"
                     /locus_tag="spr0753"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934292"
     gene            complement(749110..749751)
                     /locus_tag="spr0755"
                     /db_xref="GeneID:934290"
     CDS             complement(749110..749751)
                     /locus_tag="spr0755"
                     /note="involved in acylation of glycerol-3-phosphate to
                     form 1-acyl-glycerol-3 phosphate for use in phospholipid
                     biosynthesis; functions with PlsX"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate acyltransferase PlsY"
                     /protein_id="NP_358349.1"
                     /db_xref="GI:15902799"
                     /db_xref="GeneID:934290"
     gene            749887..751830
                     /gene="parE"
                     /locus_tag="spr0756"
                     /db_xref="GeneID:934298"
     CDS             749887..751830
                     /gene="parE"
                     /locus_tag="spr0756"
                     /EC_number="5.99.1.-"
                     /note="decatenates newly replicated chromosomal DNA and
                     relaxes positive and negative DNA supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="NP_358350.1"
                     /db_xref="GI:15902800"
                     /db_xref="GeneID:934298"
     gene            752241..754721
                     /gene="parC"
                     /locus_tag="spr0757"
                     /db_xref="GeneID:934295"
     CDS             752241..754721
                     /gene="parC"
                     /locus_tag="spr0757"
                     /EC_number="5.99.1.-"
                     /note="decatenates newly replicated chromosomal DNA and
                     relaxes positive and negative DNA supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="NP_358351.1"
                     /db_xref="GI:15902801"
                     /db_xref="GeneID:934295"
     gene            754851..755873
                     /gene="ilvE"
                     /locus_tag="spr0758"
                     /db_xref="GeneID:934293"
     CDS             754851..755873
                     /gene="ilvE"
                     /locus_tag="spr0758"
                     /EC_number="2.6.1.42"
                     /note="catalyzes the transamination of the branched-chain
                     amino acids to their respective alpha-keto acids"
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="NP_358352.1"
                     /db_xref="GI:15902802"
                     /db_xref="GeneID:934293"
     gene            756677..757387
                     /locus_tag="spr0760"
                     /db_xref="GeneID:934297"
     CDS             756677..757387
                     /locus_tag="spr0760"
                     /note="integral membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358354.1"
                     /db_xref="GI:15902804"
                     /db_xref="GeneID:934297"
     gene            757384..758307
                     /locus_tag="spr0761"
                     /db_xref="GeneID:934296"
     CDS             757384..758307
                     /locus_tag="spr0761"
                     /note="membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358355.1"
                     /db_xref="GI:15902805"
                     /db_xref="GeneID:934296"
     gene            758322..758966
                     /gene="pcp"
                     /locus_tag="spr0762"
                     /db_xref="GeneID:934303"
     CDS             758322..758966
                     /gene="pcp"
                     /locus_tag="spr0762"
                     /EC_number="3.4.19.3"
                     /note="catalyzes the removal of 5-oxoproline from various
                     penultimate amino acid residues except L-proline"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrrolidone-carboxylate peptidase"
                     /protein_id="NP_358356.1"
                     /db_xref="GI:15902806"
                     /db_xref="GeneID:934303"
     gene            759134..759364
                     /locus_tag="spr0763"
                     /db_xref="GeneID:934299"
     CDS             759134..759364
                     /locus_tag="spr0763"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358357.1"
                     /db_xref="GI:15902807"
                     /db_xref="GeneID:934299"
     gene            759414..759494
                     /gene="tRNA-Tyr1"
                     /locus_tag="sprt04"
                     /db_xref="GeneID:934302"
     tRNA            759414..759494
                     /gene="tRNA-Tyr1"
                     /locus_tag="sprt04"
                     /product="tRNA-Tyr"
                     /db_xref="GeneID:934302"
     gene            759504..759575
                     /gene="tRNA-Gln1"
                     /locus_tag="sprt05"
                     /db_xref="GeneID:934301"
     tRNA            759504..759575
                     /gene="tRNA-Gln1"
                     /locus_tag="sprt05"
                     /product="tRNA-Gln"
                     /db_xref="GeneID:934301"
     gene            759737..760939
                     /gene="rpsA"
                     /locus_tag="spr0764"
                     /db_xref="GeneID:934311"
     CDS             759737..760939
                     /gene="rpsA"
                     /locus_tag="spr0764"
                     /note="in Escherichia coli this protein is involved in
                     binding to the leader sequence of mRNAs and is itself
                     bound to the 30S subunit; autoregulates expression via a
                     C-terminal domain; in most gram negative organisms this
                     protein is composed of 6 repeats of the S1 domain while in
                     gram positive there are 4 repeats; the S1 nucleic
                     acid-binding domain is found associated with other
                     proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="NP_358358.1"
                     /db_xref="GI:15902808"
                     /db_xref="GeneID:934311"
     gene            complement(761074..761602)
                     /gene="IS1167-truncation"
                     /locus_tag="spr0765"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934305"
     gene            complement(761883..762401)
                     /gene="IS1167"
                     /locus_tag="spr0767"
                     /db_xref="GeneID:934313"
     CDS             complement(761883..762401)
                     /gene="IS1167"
                     /locus_tag="spr0767"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358361.1"
                     /db_xref="GI:15902811"
                     /db_xref="GeneID:934313"
     gene            762595..763092
                     /locus_tag="spr0768"
                     /db_xref="GeneID:934307"
     CDS             762595..763092
                     /locus_tag="spr0768"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358362.1"
                     /db_xref="GI:15902812"
                     /db_xref="GeneID:934307"
     gene            763092..764747
                     /gene="dnaX"
                     /locus_tag="spr0769"
                     /db_xref="GeneID:934308"
     CDS             763092..764747
                     /gene="dnaX"
                     /locus_tag="spr0769"
                     /EC_number="2.7.7.7"
                     /note="catalyzes the DNA-template-directed extension of
                     the 3'-end of a DNA strand; the tau chain serves as a
                     scaffold to help in the dimerizaton of the alpha,epsilon
                     and theta core complex; the gamma chain seems to interact
                     with the delta and delta' subunits to transfer the beta
                     subunit on the DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunits gamma and tau"
                     /protein_id="NP_358363.1"
                     /db_xref="GI:15902813"
                     /db_xref="GeneID:934308"
     gene            764775..764969
                     /locus_tag="spr0770"
                     /db_xref="GeneID:934314"
     CDS             764775..764969
                     /locus_tag="spr0770"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358364.1"
                     /db_xref="GI:15902814"
                     /db_xref="GeneID:934314"
     gene            765098..765889
                     /gene="ABC-NBD"
                     /locus_tag="spr0771"
                     /db_xref="GeneID:934309"
     CDS             765098..765889
                     /gene="ABC-NBD"
                     /locus_tag="spr0771"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358365.1"
                     /db_xref="GI:15902815"
                     /db_xref="GeneID:934309"
     gene            765917..767179
                     /locus_tag="spr0772"
                     /db_xref="GeneID:934310"
     CDS             765917..767179
                     /locus_tag="spr0772"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358366.1"
                     /db_xref="GI:15902816"
                     /db_xref="GeneID:934310"
     gene            767190..768416
                     /locus_tag="spr0773"
                     /db_xref="GeneID:934318"
     CDS             767190..768416
                     /locus_tag="spr0773"
                     /note="Probable class-V aminotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358367.1"
                     /db_xref="GI:15902817"
                     /db_xref="GeneID:934318"
     gene            768403..768843
                     /gene="nifU"
                     /locus_tag="spr0774"
                     /db_xref="GeneID:934312"
     CDS             768403..768843
                     /gene="nifU"
                     /locus_tag="spr0774"
                     /codon_start=1
                     /transl_table=11
                     /product="NifU protein"
                     /protein_id="NP_358368.1"
                     /db_xref="GI:15902818"
                     /db_xref="GeneID:934312"
     gene            768897..770309
                     /locus_tag="spr0775"
                     /db_xref="GeneID:934317"
     CDS             768897..770309
                     /locus_tag="spr0775"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358369.1"
                     /db_xref="GI:15902819"
                     /db_xref="GeneID:934317"
     repeat_region   770320..770460
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(770508..771749)
                     /gene="dacA"
                     /locus_tag="spr0776"
                     /db_xref="GeneID:934315"
     CDS             complement(770508..771749)
                     /gene="dacA"
                     /locus_tag="spr0776"
                     /EC_number="3.4.16.4"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="NP_358370.1"
                     /db_xref="GI:15902820"
                     /db_xref="GeneID:934315"
     gene            771852..772961
                     /locus_tag="spr0777"
                     /db_xref="GeneID:934316"
     CDS             771852..772961
                     /locus_tag="spr0777"
                     /note="permease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358371.1"
                     /db_xref="GI:15902821"
                     /db_xref="GeneID:934316"
     repeat_region   773163..773269
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            773607..773951
                     /gene="ssrA"
                     /locus_tag="sprs03"
                     /db_xref="GeneID:934320"
     tmRNA           773607..773951
                     /gene="ssrA"
                     /locus_tag="sprs03"
                     /db_xref="GeneID:934320"
     gene            complement(774137..774224)
                     /gene="tRNA-Ser1"
                     /locus_tag="sprt06"
                     /db_xref="GeneID:934322"
     tRNA            complement(774137..774224)
                     /gene="tRNA-Ser1"
                     /locus_tag="sprt06"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:934322"
     gene            774386..775126
                     /gene="fruR"
                     /locus_tag="spr0778"
                     /db_xref="GeneID:934319"
     CDS             774386..775126
                     /gene="fruR"
                     /locus_tag="spr0778"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose PTS system repressor"
                     /protein_id="NP_358372.1"
                     /db_xref="GI:15902822"
                     /db_xref="GeneID:934319"
     gene            775123..776034
                     /gene="fruB"
                     /locus_tag="spr0779"
                     /db_xref="GeneID:934324"
     CDS             775123..776034
                     /gene="fruB"
                     /locus_tag="spr0779"
                     /EC_number="2.7.1.56"
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="NP_358373.1"
                     /db_xref="GI:15902823"
                     /db_xref="GeneID:934324"
     gene            776031..777983
                     /gene="fruA"
                     /locus_tag="spr0780"
                     /db_xref="GeneID:934325"
     CDS             776031..777983
                     /gene="fruA"
                     /locus_tag="spr0780"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system fructose specific transporter subunit
                     IIABC"
                     /protein_id="NP_358374.1"
                     /db_xref="GI:15902824"
                     /db_xref="GeneID:934325"
     gene            778069..780372
                     /gene="ftsK"
                     /locus_tag="spr0781"
                     /db_xref="GeneID:934321"
     CDS             778069..780372
                     /gene="ftsK"
                     /locus_tag="spr0781"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoE family protein"
                     /protein_id="NP_358375.1"
                     /db_xref="GI:15902825"
                     /db_xref="GeneID:934321"
     gene            complement(780417..780950)
                     /locus_tag="spr0782"
                     /db_xref="GeneID:934327"
     CDS             complement(780417..780950)
                     /locus_tag="spr0782"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358376.1"
                     /db_xref="GI:15902826"
                     /db_xref="GeneID:934327"
     gene            780983..782125
                     /locus_tag="spr0783"
                     /db_xref="GeneID:934333"
     CDS             780983..782125
                     /locus_tag="spr0783"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent aminotransferase"
                     /protein_id="NP_358377.1"
                     /db_xref="GI:15902827"
                     /db_xref="GeneID:934333"
     gene            782134..783348
                     /gene="thiI"
                     /locus_tag="spr0784"
                     /db_xref="GeneID:934323"
     CDS             782134..783348
                     /gene="thiI"
                     /locus_tag="spr0784"
                     /note="Required for the synthesis of the thiazole moiety"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ThiI"
                     /protein_id="NP_358378.1"
                     /db_xref="GI:15902828"
                     /db_xref="GeneID:934323"
     gene            783459..784307
                     /locus_tag="spr0785"
                     /db_xref="GeneID:934329"
     CDS             783459..784307
                     /locus_tag="spr0785"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358379.1"
                     /db_xref="GI:15902829"
                     /db_xref="GeneID:934329"
     gene            784329..785068
                     /locus_tag="spr0786"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934326"
     gene            785081..786247
                     /locus_tag="spr0789"
                     /db_xref="GeneID:934330"
     CDS             785081..786247
                     /locus_tag="spr0789"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358383.1"
                     /db_xref="GI:15902833"
                     /db_xref="GeneID:934330"
     repeat_region   complement(786503..786650)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            786755..788248
                     /gene="hsdM"
                     /locus_tag="spr0790"
                     /db_xref="GeneID:934337"
     CDS             786755..788248
                     /gene="hsdM"
                     /locus_tag="spr0790"
                     /EC_number="2.1.1.72"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system M
                     subunit"
                     /protein_id="NP_358384.1"
                     /db_xref="GI:15902834"
                     /db_xref="GeneID:934337"
     gene            788261..788872
                     /gene="hsdS"
                     /locus_tag="spr0791"
                     /db_xref="GeneID:934328"
     CDS             788261..788872
                     /gene="hsdS"
                     /locus_tag="spr0791"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system S
                     subunit"
                     /protein_id="NP_358385.1"
                     /db_xref="GI:15902835"
                     /db_xref="GeneID:934328"
     gene            788951..792301
                     /gene="hsdR"
                     /locus_tag="spr0792"
                     /db_xref="GeneID:934335"
     CDS             788951..792301
                     /gene="hsdR"
                     /locus_tag="spr0792"
                     /EC_number="3.1.21.3"
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system R
                     subunit"
                     /protein_id="NP_358386.1"
                     /db_xref="GI:15902836"
                     /db_xref="REBASE:SpnRORF790P"
                     /db_xref="GeneID:934335"
     repeat_region   complement(792564..792759)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            792572..792772
                     /locus_tag="spr0792a"
                     /db_xref="GeneID:17374507"
     CDS             792572..792772
                     /locus_tag="spr0792a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719802.1"
                     /db_xref="GI:555247348"
                     /db_xref="GeneID:17374507"
     gene            complement(792887..793357)
                     /gene="argR"
                     /locus_tag="spr0793"
                     /db_xref="GeneID:934338"
     CDS             complement(792887..793357)
                     /gene="argR"
                     /locus_tag="spr0793"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor ArgR"
                     /protein_id="NP_358387.1"
                     /db_xref="GI:15902837"
                     /db_xref="GeneID:934338"
     gene            complement(793374..795761)
                     /gene="pepXP"
                     /locus_tag="spr0794"
                     /db_xref="GeneID:934358"
     CDS             complement(793374..795761)
                     /gene="pepXP"
                     /locus_tag="spr0794"
                     /EC_number="3.4.14.11"
                     /note="catalyzes the removal of N-terminal dipeptides when
                     proline is the penultimate residue"
                     /codon_start=1
                     /transl_table=11
                     /product="x-prolyl-dipeptidyl aminopeptidase"
                     /protein_id="NP_358388.1"
                     /db_xref="GI:15902838"
                     /db_xref="GeneID:934358"
     gene            795966..799094
                     /gene="dnaE"
                     /locus_tag="spr0795"
                     /db_xref="GeneID:934341"
     CDS             795966..799094
                     /gene="dnaE"
                     /locus_tag="spr0795"
                     /EC_number="2.7.7.7"
                     /note="Catalyzes DNA-template-directed extension of the
                     3'-end of a DNA strand by one nucleotide at a time.
                     Proposed to be responsible for the synthesis of the
                     lagging strand. In the low GC gram positive bacteria this
                     enzyme is less processive and more error prone than its
                     counterpart in other bacteria."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III DnaE"
                     /protein_id="NP_358389.1"
                     /db_xref="GI:15902839"
                     /db_xref="GeneID:934341"
     gene            799177..800184
                     /gene="pfkA"
                     /locus_tag="spr0796"
                     /db_xref="GeneID:934334"
     CDS             799177..800184
                     /gene="pfkA"
                     /locus_tag="spr0796"
                     /EC_number="2.7.1.11"
                     /note="catalyzes the formation of D-fructose
                     1,6-bisphosphate from D-fructose 6-phosphate in
                     glycolysis"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="NP_358390.1"
                     /db_xref="GI:15902840"
                     /db_xref="GeneID:934334"
     gene            800243..801748
                     /gene="pykF"
                     /locus_tag="spr0797"
                     /db_xref="GeneID:934336"
     CDS             800243..801748
                     /gene="pykF"
                     /locus_tag="spr0797"
                     /EC_number="2.7.1.40"
                     /note="catalyzes the formation of phosphoenolpyruvate from
                     pyruvate"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="NP_358391.1"
                     /db_xref="GI:15902841"
                     /db_xref="GeneID:934336"
     repeat_region   801849..801998
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     repeat_region   complement(801997..802062)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup"
     repeat_region   803190..803263
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            803555..804427
                     /locus_tag="spr0799"
                     /db_xref="GeneID:934343"
     CDS             803555..804427
                     /locus_tag="spr0799"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358393.1"
                     /db_xref="GI:15902843"
                     /db_xref="GeneID:934343"
     gene            complement(804534..804917)
                     /gene="IS1381-truncation"
                     /locus_tag="spr0801"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934346"
     gene            805060..805371
                     /locus_tag="spr0802"
                     /db_xref="GeneID:934344"
     CDS             805060..805371
                     /locus_tag="spr0802"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358396.1"
                     /db_xref="GI:15902846"
                     /db_xref="GeneID:934344"
     gene            805375..806091
                     /locus_tag="spr0803"
                     /db_xref="GeneID:934347"
     CDS             805375..806091
                     /locus_tag="spr0803"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358397.1"
                     /db_xref="GI:15902847"
                     /db_xref="GeneID:934347"
     gene            complement(806221..807036)
                     /locus_tag="spr0804"
                     /db_xref="GeneID:934349"
     CDS             complement(806221..807036)
                     /locus_tag="spr0804"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358398.1"
                     /db_xref="GI:15902848"
                     /db_xref="GeneID:934349"
     gene            complement(807033..807938)
                     /locus_tag="spr0805"
                     /db_xref="GeneID:934351"
     CDS             complement(807033..807938)
                     /locus_tag="spr0805"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358399.1"
                     /db_xref="GI:15902849"
                     /db_xref="GeneID:934351"
     gene            808280..809649
                     /locus_tag="spr0806"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934345"
     gene            809733..811880
                     /gene="tex"
                     /locus_tag="spr0808"
                     /db_xref="GeneID:934350"
     CDS             809733..811880
                     /gene="tex"
                     /locus_tag="spr0808"
                     /codon_start=1
                     /transl_table=11
                     /product="toxin expression transcriptional accessory
                     protein"
                     /protein_id="NP_358402.1"
                     /db_xref="GI:15902852"
                     /db_xref="GeneID:934350"
     gene            811867..812316
                     /locus_tag="spr0809"
                     /db_xref="GeneID:934348"
     CDS             811867..812316
                     /locus_tag="spr0809"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358403.1"
                     /db_xref="GI:15902853"
                     /db_xref="GeneID:934348"
     gene            812345..812647
                     /locus_tag="spr0810"
                     /db_xref="GeneID:934356"
     CDS             812345..812647
                     /locus_tag="spr0810"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358404.1"
                     /db_xref="GI:15902854"
                     /db_xref="GeneID:934356"
     repeat_region   812863..812969
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(813001..813192)
                     /locus_tag="spr0811"
                     /db_xref="GeneID:934355"
     CDS             complement(813001..813192)
                     /locus_tag="spr0811"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358405.1"
                     /db_xref="GI:15902855"
                     /db_xref="GeneID:934355"
     gene            813563..814378
                     /gene="ABC-NBD"
                     /locus_tag="spr0812"
                     /db_xref="GeneID:934359"
     CDS             813563..814378
                     /gene="ABC-NBD"
                     /locus_tag="spr0812"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358406.1"
                     /db_xref="GI:15902856"
                     /db_xref="GeneID:934359"
     gene            814380..816368
                     /gene="ABC-MSD"
                     /locus_tag="spr0813"
                     /db_xref="GeneID:934353"
     CDS             814380..816368
                     /gene="ABC-MSD"
                     /locus_tag="spr0813"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_358407.1"
                     /db_xref="GI:15902857"
                     /db_xref="GeneID:934353"
     gene            complement(816411..817001)
                     /locus_tag="spr0814"
                     /db_xref="GeneID:934354"
     CDS             complement(816411..817001)
                     /locus_tag="spr0814"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358408.1"
                     /db_xref="GI:15902858"
                     /db_xref="GeneID:934354"
     gene            complement(817081..818001)
                     /locus_tag="spr0815"
                     /db_xref="GeneID:934360"
     CDS             complement(817081..818001)
                     /locus_tag="spr0815"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358409.1"
                     /db_xref="GI:15902859"
                     /db_xref="GeneID:934360"
     repeat_region   complement(818105..818211)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            818663..820138
                     /gene="cad"
                     /locus_tag="spr0816"
                     /db_xref="GeneID:934357"
     CDS             818663..820138
                     /gene="cad"
                     /locus_tag="spr0816"
                     /EC_number="4.1.1.18"
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase"
                     /protein_id="NP_358410.1"
                     /db_xref="GI:15902860"
                     /db_xref="GeneID:934357"
     gene            complement(820104..820819)
                     /gene="transposase_F"
                     /locus_tag="spr0817"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934368"
     gene            821075..821935
                     /gene="speE"
                     /locus_tag="spr0819"
                     /db_xref="GeneID:934362"
     CDS             821075..821935
                     /gene="speE"
                     /locus_tag="spr0819"
                     /EC_number="2.5.1.16"
                     /note="catalyzes the formation of spermidine from
                     putrescine and S-adenosylmethioninamine"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine synthase"
                     /protein_id="NP_358413.1"
                     /db_xref="GI:15902863"
                     /db_xref="GeneID:934362"
     gene            821932..823191
                     /locus_tag="spr0820"
                     /db_xref="GeneID:934369"
     CDS             821932..823191
                     /locus_tag="spr0820"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358414.1"
                     /db_xref="GI:15902864"
                     /db_xref="GeneID:934369"
     gene            823191..824318
                     /gene="nspC"
                     /locus_tag="spr0821"
                     /db_xref="GeneID:934364"
     CDS             823191..824318
                     /gene="nspC"
                     /locus_tag="spr0821"
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="NP_358415.1"
                     /db_xref="GI:15902865"
                     /db_xref="GeneID:934364"
     gene            824315..825400
                     /locus_tag="spr0822"
                     /db_xref="GeneID:934363"
     CDS             824315..825400
                     /locus_tag="spr0822"
                     /note="catalyzes the formation of carbamoylputrescine from
                     agmatine in the arginine decarboxylase pathway of
                     putrescine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="NP_358416.1"
                     /db_xref="GI:15902866"
                     /db_xref="GeneID:934363"
     gene            825410..826285
                     /gene="but"
                     /locus_tag="spr0823"
                     /db_xref="GeneID:934377"
     CDS             825410..826285
                     /gene="but"
                     /locus_tag="spr0823"
                     /EC_number="3.5.1.6"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-alanine synthase or beta-ureidopropionase"
                     /protein_id="NP_358417.1"
                     /db_xref="GI:15902867"
                     /db_xref="GeneID:934377"
     gene            complement(826466..827275)
                     /locus_tag="spr0824"
                     /db_xref="GeneID:934365"
     CDS             complement(826466..827275)
                     /locus_tag="spr0824"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_358418.1"
                     /db_xref="GI:15902868"
                     /db_xref="GeneID:934365"
     gene            827547..827768
                     /locus_tag="spr0825"
                     /db_xref="GeneID:934366"
     CDS             827547..827768
                     /locus_tag="spr0825"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358419.1"
                     /db_xref="GI:15902869"
                     /db_xref="GeneID:934366"
     gene            827822..828493
                     /locus_tag="spr0826"
                     /db_xref="GeneID:934373"
     CDS             827822..828493
                     /locus_tag="spr0826"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358420.1"
                     /db_xref="GI:15902870"
                     /db_xref="GeneID:934373"
     gene            828735..829643
                     /gene="cpsY"
                     /locus_tag="spr0828"
                     /db_xref="GeneID:934370"
     CDS             828735..829643
                     /gene="cpsY"
                     /locus_tag="spr0828"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory function on capsule expression in
                     group B streptococci"
                     /protein_id="NP_358422.1"
                     /db_xref="GI:15902872"
                     /db_xref="GeneID:934370"
     gene            829640..830101
                     /gene="lspA"
                     /locus_tag="spr0829"
                     /db_xref="GeneID:934374"
     CDS             829640..830101
                     /gene="lspA"
                     /locus_tag="spr0829"
                     /note="lipoprotein signal peptidase; integral membrane
                     protein that removes signal peptides from prolipoproteins
                     during lipoprotein biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein signal peptidase"
                     /protein_id="NP_358423.1"
                     /db_xref="GI:15902873"
                     /db_xref="GeneID:934374"
     gene            830091..830978
                     /gene="rluD"
                     /locus_tag="spr0830"
                     /db_xref="GeneID:934371"
     CDS             830091..830978
                     /gene="rluD"
                     /locus_tag="spr0830"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     D"
                     /protein_id="NP_358424.1"
                     /db_xref="GI:15902874"
                     /db_xref="GeneID:934371"
     gene            830981..832864
                     /gene="lytD"
                     /locus_tag="spr0831"
                     /db_xref="GeneID:934372"
     CDS             830981..832864
                     /gene="lytD"
                     /locus_tag="spr0831"
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding protein E"
                     /protein_id="NP_358425.1"
                     /db_xref="GI:15902875"
                     /db_xref="GeneID:934372"
     gene            832944..834074
                     /gene="proB"
                     /locus_tag="spr0832"
                     /db_xref="GeneID:934389"
     CDS             832944..834074
                     /gene="proB"
                     /locus_tag="spr0832"
                     /EC_number="2.7.2.11"
                     /note="catalyzes the formation of glutamate 5-phosphate
                     from glutamate in proline biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl kinase"
                     /protein_id="NP_358426.1"
                     /db_xref="GI:15902876"
                     /db_xref="GeneID:934389"
     gene            834084..835346
                     /gene="proA"
                     /locus_tag="spr0833"
                     /db_xref="GeneID:934375"
     CDS             834084..835346
                     /gene="proA"
                     /locus_tag="spr0833"
                     /EC_number="1.2.1.41"
                     /note="Catalyzes the phosphorylation of L-glutamate during
                     the proline biosynthesis pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl phosphate reductase"
                     /protein_id="NP_358427.1"
                     /db_xref="GI:15902877"
                     /db_xref="GeneID:934375"
     gene            835350..836147
                     /gene="proC"
                     /locus_tag="spr0834"
                     /db_xref="GeneID:934378"
     CDS             835350..836147
                     /gene="proC"
                     /locus_tag="spr0834"
                     /EC_number="1.5.1.2"
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="NP_358428.1"
                     /db_xref="GI:15902878"
                     /db_xref="GeneID:934378"
     gene            836263..836901
                     /gene="tmk"
                     /locus_tag="spr0835"
                     /db_xref="GeneID:934382"
     CDS             836263..836901
                     /gene="tmk"
                     /locus_tag="spr0835"
                     /EC_number="2.7.4.9"
                     /note="catalyzes the reversible phosphoryl transfer from
                     adenosine triphosphate (ATP) to thymidine monophosphate
                     (dTMP) to form thymidine diphosphate (dTDP)"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="NP_358429.1"
                     /db_xref="GI:15902879"
                     /db_xref="GeneID:934382"
     gene            836898..837788
                     /gene="holB"
                     /locus_tag="spr0836"
                     /db_xref="GeneID:934380"
     CDS             836898..837788
                     /gene="holB"
                     /locus_tag="spr0836"
                     /EC_number="2.7.7.7"
                     /note="catalyzes the DNA-template-directed extension of
                     the 3'-end of a DNA strand; the delta' subunit seems to
                     interact with the gamma subunit to transfer the beta
                     subunit on the DNA."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="NP_358430.1"
                     /db_xref="GI:15902880"
                     /db_xref="GeneID:934380"
     gene            837801..838145
                     /locus_tag="spr0837"
                     /db_xref="GeneID:934376"
     CDS             837801..838145
                     /locus_tag="spr0837"
                     /note="in Bacillus subtilis this protein is involved in
                     the negative regulation of DNA replication initiation;
                     interacts with DnaN and DnaA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication intiation control protein YabA"
                     /protein_id="NP_358431.1"
                     /db_xref="GI:15902881"
                     /db_xref="GeneID:934376"
     gene            838148..839017
                     /locus_tag="spr0838"
                     /db_xref="GeneID:934385"
     CDS             838148..839017
                     /locus_tag="spr0838"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358432.1"
                     /db_xref="GI:15902882"
                     /db_xref="GeneID:934385"
     gene            839217..839762
                     /locus_tag="spr0839"
                     /db_xref="GeneID:934379"
     CDS             839217..839762
                     /locus_tag="spr0839"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358433.1"
                     /db_xref="GI:15902883"
                     /db_xref="GeneID:934379"
     gene            839871..840518
                     /locus_tag="spr0840"
                     /db_xref="GeneID:934381"
     CDS             839871..840518
                     /locus_tag="spr0840"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358434.1"
                     /db_xref="GI:15902884"
                     /db_xref="GeneID:934381"
     gene            complement(840507..840896)
                     /gene="IS1381"
                     /locus_tag="spr0841"
                     /db_xref="GeneID:934387"
     CDS             complement(840507..840896)
                     /gene="IS1381"
                     /locus_tag="spr0841"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_358435.1"
                     /db_xref="GI:15902885"
                     /db_xref="GeneID:934387"
     gene            complement(840922..841311)
                     /gene="IS1381"
                     /locus_tag="spr0842"
                     /db_xref="GeneID:934383"
     CDS             complement(840922..841311)
                     /gene="IS1381"
                     /locus_tag="spr0842"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_358436.1"
                     /db_xref="GI:15902886"
                     /db_xref="GeneID:934383"
     gene            841805..843139
                     /gene="gidA"
                     /locus_tag="spr0844"
                     /gene_synonym="gid"
                     /db_xref="GeneID:934391"
     CDS             841805..843139
                     /gene="gidA"
                     /locus_tag="spr0844"
                     /gene_synonym="gid"
                     /note="TrmFO; Gid; glucose-inhibited division protein;
                     similar to GidA; the gene from Bacillus subtilis encodes a
                     tRNA-methyltransferase that utilizes folate as the carbon
                     donor and bound flavin as reductant; modifies tRNA at
                     position 54 (uridine) of the T-psi loop to form a
                     C5-methyluridine"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uracil-5-)-methyltransferase Gid"
                     /protein_id="NP_358438.1"
                     /db_xref="GI:15902888"
                     /db_xref="GeneID:934391"
     gene            843217..843960
                     /gene="pyrH"
                     /locus_tag="spr0845"
                     /db_xref="GeneID:934386"
     CDS             843217..843960
                     /gene="pyrH"
                     /locus_tag="spr0845"
                     /EC_number="2.7.4.-"
                     /note="Catalyzes the phosphorylation of UMP to UDP"
                     /codon_start=1
                     /transl_table=11
                     /product="uridylate kinase"
                     /protein_id="NP_358439.1"
                     /db_xref="GI:15902889"
                     /db_xref="GeneID:934386"
     gene            843969..844526
                     /gene="frr"
                     /locus_tag="spr0846"
                     /db_xref="GeneID:934401"
     CDS             843969..844526
                     /gene="frr"
                     /locus_tag="spr0846"
                     /note="Rrf; Frr; ribosome-recycling factor; release factor
                     4; RF4; recycles ribosomes upon translation termination
                     along with release factor RF-3 and elongation factor EF-G;
                     A GTPase-dependent process results in release of 50S from
                     70S; inhibited by release factor RF-1; essential for
                     viability; structurally similar to tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="NP_358440.1"
                     /db_xref="GI:15902890"
                     /db_xref="GeneID:934401"
     gene            844547..845440
                     /locus_tag="spr0847"
                     /db_xref="GeneID:934394"
     CDS             844547..845440
                     /locus_tag="spr0847"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358441.1"
                     /db_xref="GI:15902891"
                     /db_xref="GeneID:934394"
     gene            845449..845664
                     /locus_tag="spr0848"
                     /db_xref="GeneID:934388"
     CDS             845449..845664
                     /locus_tag="spr0848"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358442.1"
                     /db_xref="GI:15902892"
                     /db_xref="GeneID:934388"
     gene            845750..846718
                     /gene="phoL"
                     /locus_tag="spr0849"
                     /db_xref="GeneID:934390"
     CDS             845750..846718
                     /gene="phoL"
                     /locus_tag="spr0849"
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="NP_358443.1"
                     /db_xref="GI:15902893"
                     /db_xref="GeneID:934390"
     gene            846911..847411
                     /locus_tag="spr0850"
                     /db_xref="GeneID:934396"
     CDS             846911..847411
                     /locus_tag="spr0850"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358444.1"
                     /db_xref="GI:15902894"
                     /db_xref="GeneID:934396"
     gene            847414..847740
                     /locus_tag="spr0851"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934392"
     gene            complement(848041..849152)
                     /gene="ald-truncation"
                     /locus_tag="spr0852"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934393"
     gene            849329..849898
                     /locus_tag="spr0855"
                     /db_xref="GeneID:934395"
     CDS             849329..849898
                     /locus_tag="spr0855"
                     /note="Probable acetyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358449.1"
                     /db_xref="GI:15902899"
                     /db_xref="GeneID:934395"
     gene            849966..850616
                     /gene="celA"
                     /locus_tag="spr0856"
                     /db_xref="GeneID:934400"
     CDS             849966..850616
                     /gene="celA"
                     /locus_tag="spr0856"
                     /note="Competence induced; comE-like protein A also known
                     as CilE; DNA uptake by homology"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CelA"
                     /protein_id="NP_358450.1"
                     /db_xref="GI:15902900"
                     /db_xref="GeneID:934400"
     gene            850600..852840
                     /gene="celB"
                     /locus_tag="spr0857"
                     /db_xref="GeneID:934397"
     CDS             850600..852840
                     /gene="celB"
                     /locus_tag="spr0857"
                     /note="Competence induced; comE-like protein B; DNA uptake
                     by homology"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CelB"
                     /protein_id="NP_358451.1"
                     /db_xref="GI:15902901"
                     /db_xref="GeneID:934397"
     gene            853239..853826
                     /locus_tag="spr0859"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934405"
     gene            853830..855011
                     /locus_tag="spr0860"
                     /db_xref="GeneID:934399"
     CDS             853830..855011
                     /locus_tag="spr0860"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358454.1"
                     /db_xref="GI:15902904"
                     /db_xref="GeneID:934399"
     gene            855261..855848
                     /gene="infC"
                     /locus_tag="spr0861"
                     /db_xref="GeneID:934403"
     CDS             855261..855848
                     /gene="infC"
                     /locus_tag="spr0861"
                     /note="IF-3 has several functions that are required and
                     promote translation initiation including; preventing
                     association of 70S by binding to 30S; monitoring
                     codon-anticodon interactions by promoting disassociation
                     of fMet-tRNA(fMet) from initiation complexes formed on
                     leaderless mRNAs or incorrectly bound noninitiatior tRNAs
                     and complexes with noncanonical start sites; stimulates
                     codon-anticodon interactions at P-site; involved in moving
                     mRNA to the P-site; and in recycling subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="NP_358455.1"
                     /db_xref="GI:15902905"
                     /db_xref="GeneID:934403"
     gene            855881..856081
                     /gene="rpmI"
                     /locus_tag="spr0862"
                     /db_xref="GeneID:933877"
     CDS             855881..856081
                     /gene="rpmI"
                     /locus_tag="spr0862"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="NP_358456.1"
                     /db_xref="GI:15902906"
                     /db_xref="GeneID:933877"
     gene            856133..856492
                     /gene="rplT"
                     /locus_tag="spr0863"
                     /db_xref="GeneID:934411"
     CDS             856133..856492
                     /gene="rplT"
                     /locus_tag="spr0863"
                     /note="binds directly to 23S ribosomal RNA prior to in
                     vitro assembly of the 50S ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="NP_358457.1"
                     /db_xref="GI:15902907"
                     /db_xref="GeneID:934411"
     gene            856499..856930
                     /gene="lguL"
                     /locus_tag="spr0864"
                     /db_xref="GeneID:934408"
     CDS             856499..856930
                     /gene="lguL"
                     /locus_tag="spr0864"
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="NP_358458.1"
                     /db_xref="GI:15902908"
                     /db_xref="GeneID:934408"
     gene            857180..857980
                     /gene="pyrDII"
                     /locus_tag="spr0865"
                     /db_xref="GeneID:933866"
     CDS             857180..857980
                     /gene="pyrDII"
                     /locus_tag="spr0865"
                     /EC_number="1.3.5.2"
                     /note="responsible for channeling the electrons from the
                     oxidation of dihydroorotate from the FMN redox center in
                     the pyrD subunit to the ultimate electron acceptor NAD(+)"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="NP_358459.1"
                     /db_xref="GI:15902909"
                     /db_xref="GeneID:933866"
     gene            857991..858929
                     /gene="pyrD"
                     /locus_tag="spr0866"
                     /db_xref="GeneID:934407"
     CDS             857991..858929
                     /gene="pyrD"
                     /locus_tag="spr0866"
                     /note="catalyzes the conversion of dihydroorotate to
                     orotate in the pyrimidine biosynthesis pathway, using a
                     flavin nucleotide as an essential cofactor; subclass 1B is
                     a heterotetramer consisting of two PyrDB subunits, similar
                     to the PyrDA subunits and two PyrK subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase 1B"
                     /protein_id="NP_358460.2"
                     /db_xref="GI:161410749"
                     /db_xref="GeneID:934407"
     gene            858971..861136
                     /gene="lytB"
                     /locus_tag="spr0867"
                     /db_xref="GeneID:934406"
     CDS             858971..861136
                     /gene="lytB"
                     /locus_tag="spr0867"
                     /EC_number="3.2.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="NP_358461.1"
                     /db_xref="GI:15902911"
                     /db_xref="GeneID:934406"
     gene            complement(861197..862879)
                     /gene="flpA"
                     /locus_tag="spr0868"
                     /db_xref="GeneID:933098"
     CDS             complement(861197..862879)
                     /gene="flpA"
                     /locus_tag="spr0868"
                     /codon_start=1
                     /transl_table=11
                     /product="adherence and virulence protein A"
                     /protein_id="NP_358462.1"
                     /db_xref="GI:15902912"
                     /db_xref="GeneID:933098"
     gene            862957..863454
                     /locus_tag="spr0869"
                     /db_xref="GeneID:934173"
     CDS             862957..863454
                     /locus_tag="spr0869"
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease"
                     /protein_id="NP_358463.1"
                     /db_xref="GI:15902913"
                     /db_xref="GeneID:934173"
     gene            863435..863830
                     /gene="dgkA"
                     /locus_tag="spr0870"
                     /db_xref="GeneID:933031"
     CDS             863435..863830
                     /gene="dgkA"
                     /locus_tag="spr0870"
                     /EC_number="2.7.1.107"
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="NP_358464.1"
                     /db_xref="GI:15902914"
                     /db_xref="GeneID:933031"
     gene            863847..864746
                     /gene="era"
                     /locus_tag="spr0871"
                     /gene_synonym="bex; rbaA; sdgE; yqfH"
                     /db_xref="GeneID:933913"
     CDS             863847..864746
                     /gene="era"
                     /locus_tag="spr0871"
                     /gene_synonym="bex; rbaA; sdgE; yqfH"
                     /note="Era; Escherichia coli Ras-like protein; Bex;
                     Bacillus Era-complementing segment; essential protein in
                     Escherichia coli that is involved in many cellular
                     processes; GTPase; binds the cell membrane through
                     apparent C-terminal domain; mutants are arrested during
                     the cell cycle; Streptococcus pneumoniae Era binds to RNA
                     and Escherichia coli Era binds 16S rRNA and 30S ribosome"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein Era"
                     /protein_id="NP_358465.1"
                     /db_xref="GI:15902915"
                     /db_xref="GeneID:933913"
     gene            864795..865619
                     /gene="mutM"
                     /locus_tag="spr0872"
                     /db_xref="GeneID:933206"
     CDS             864795..865619
                     /gene="mutM"
                     /locus_tag="spr0872"
                     /EC_number="3.2.2.23"
                     /note="Involved in base excision repair of DNA damaged by
                     oxidation or by mutagenic agents. Acts as DNA glycosylase
                     that recognizes and removes damaged bases"
                     /codon_start=1
                     /transl_table=11
                     /product="formamidopyrimidine-DNA glycosylase"
                     /protein_id="NP_358466.1"
                     /db_xref="GI:15902916"
                     /db_xref="GeneID:933206"
     gene            865592..866224
                     /gene="coaE"
                     /locus_tag="spr0873"
                     /db_xref="GeneID:932960"
     CDS             865592..866224
                     /gene="coaE"
                     /locus_tag="spr0873"
                     /EC_number="2.7.1.24"
                     /note="catalyzes the phosphorylation of the 3'-hydroxyl
                     group of dephosphocoenzyme A to form coenzyme A; involved
                     in coenzyme A biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="NP_358467.1"
                     /db_xref="GI:15902917"
                     /db_xref="GeneID:932960"
     gene            866211..867410
                     /gene="pmrA"
                     /locus_tag="spr0875"
                     /db_xref="GeneID:933710"
     CDS             866211..867410
                     /gene="pmrA"
                     /locus_tag="spr0875"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator superfamily multi-drug
                     resistance efflux pump"
                     /protein_id="NP_358469.1"
                     /db_xref="GI:15902919"
                     /db_xref="GeneID:933710"
     gene            867410..867559
                     /gene="rpmG"
                     /locus_tag="spr0876"
                     /db_xref="GeneID:933739"
     CDS             867410..867559
                     /gene="rpmG"
                     /locus_tag="spr0876"
                     /note="in Escherichia coli BM108, a mutation that results
                     in lack of L33 synthesis had no effect on ribosome
                     synthesis or function; there are paralogous genes in
                     several bacterial genomes, and a CXXC motif for zinc
                     binding and an upstream regulation region of the paralog
                     lacking this motif that are regulated by zinc similar to
                     other ribosomal proteins like L31; the proteins in this
                     group lack the CXXC motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="NP_358470.1"
                     /db_xref="GI:15902920"
                     /db_xref="GeneID:933739"
     gene            867599..867832
                     /gene="secG"
                     /locus_tag="spr0877"
                     /db_xref="GeneID:933638"
     CDS             867599..867832
                     /gene="secG"
                     /locus_tag="spr0877"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="NP_358471.1"
                     /db_xref="GI:15902921"
                     /db_xref="GeneID:933638"
     gene            867934..870288
                     /gene="rnr"
                     /locus_tag="spr0878"
                     /db_xref="GeneID:932871"
     CDS             867934..870288
                     /gene="rnr"
                     /locus_tag="spr0878"
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease R"
                     /protein_id="NP_358472.1"
                     /db_xref="GI:15902922"
                     /db_xref="GeneID:932871"
     gene            870251..870718
                     /gene="smpB"
                     /locus_tag="spr0879"
                     /db_xref="GeneID:933888"
     CDS             870251..870718
                     /gene="smpB"
                     /locus_tag="spr0879"
                     /note="binds to ssrA RNA (tmRNA) and is required for its
                     successful binding to ribosomes; also appears to function
                     in the trans-translation step by promoting accommodation
                     of tmRNA into the ribosomal A site; SmpB protects the
                     tmRNA from RNase R degradation in Caulobacter crescentus;
                     both the tmRNA and SmpB are regulated in cell
                     cycle-dependent manner; functions in release of stalled
                     ribosomes from damaged mRNAs and targeting proteins for
                     degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein"
                     /protein_id="NP_358473.1"
                     /db_xref="GI:15902923"
                     /db_xref="GeneID:933888"
     gene            870728..871594
                     /gene="tehB"
                     /locus_tag="spr0880"
                     /db_xref="GeneID:932916"
     CDS             870728..871594
                     /gene="tehB"
                     /locus_tag="spr0880"
                     /note="with TehA confers resistance to tellurite"
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance protein TehB"
                     /protein_id="NP_358474.1"
                     /db_xref="GI:15902924"
                     /db_xref="GeneID:932916"
     gene            871667..872620
                     /gene="coiA"
                     /locus_tag="spr0881"
                     /db_xref="GeneID:933951"
     CDS             871667..872620
                     /gene="coiA"
                     /locus_tag="spr0881"
                     /note="Competence induced protein A"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="NP_358475.1"
                     /db_xref="GI:15902925"
                     /db_xref="GeneID:933951"
     gene            872639..874441
                     /gene="pepB"
                     /locus_tag="spr0882"
                     /db_xref="GeneID:933006"
     CDS             872639..874441
                     /gene="pepB"
                     /locus_tag="spr0882"
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="NP_358476.1"
                     /db_xref="GI:15902926"
                     /db_xref="GeneID:933006"
     gene            874443..875156
                     /locus_tag="spr0883"
                     /db_xref="GeneID:933962"
     CDS             874443..875156
                     /locus_tag="spr0883"
                     /note="Probable methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="NP_358477.1"
                     /db_xref="GI:15902927"
                     /db_xref="GeneID:933962"
     gene            875223..876164
                     /gene="prsA"
                     /locus_tag="spr0884"
                     /db_xref="GeneID:932962"
     CDS             875223..876164
                     /gene="prsA"
                     /locus_tag="spr0884"
                     /EC_number="5.2.1.8"
                     /note="cis/trans isomerase of peptidylprolyl; PPIase;
                     membrane-bound lipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="foldase PrsA"
                     /protein_id="NP_358478.1"
                     /db_xref="GI:15902928"
                     /db_xref="GeneID:932962"
     gene            complement(876270..876623)
                     /gene="IS861-truncation"
                     /locus_tag="spr0885"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933879"
     repeat_region   complement(876879..877013)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(877383..878003)
                     /gene="gpmB"
                     /locus_tag="spr0887"
                     /db_xref="GeneID:933141"
     CDS             complement(877383..878003)
                     /gene="gpmB"
                     /locus_tag="spr0887"
                     /EC_number="5.4.2.1"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="NP_358481.1"
                     /db_xref="GI:15902931"
                     /db_xref="GeneID:933141"
     gene            complement(878003..878485)
                     /gene="ebsC"
                     /locus_tag="spr0888"
                     /db_xref="GeneID:932797"
     CDS             complement(878003..878485)
                     /gene="ebsC"
                     /locus_tag="spr0888"
                     /codon_start=1
                     /transl_table=11
                     /product="regulatory protein"
                     /protein_id="NP_358482.1"
                     /db_xref="GI:15902932"
                     /db_xref="GeneID:932797"
     gene            complement(878485..879327)
                     /locus_tag="spr0889"
                     /db_xref="GeneID:932840"
     CDS             complement(878485..879327)
                     /locus_tag="spr0889"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358483.1"
                     /db_xref="GI:15902933"
                     /db_xref="GeneID:932840"
     gene            complement(879422..880222)
                     /locus_tag="spr0890"
                     /db_xref="GeneID:933046"
     CDS             complement(879422..880222)
                     /locus_tag="spr0890"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358484.1"
                     /db_xref="GI:15902934"
                     /db_xref="GeneID:933046"
     gene            880306..881745
                     /gene="glmU"
                     /locus_tag="spr0891"
                     /db_xref="GeneID:933167"
     CDS             880306..881745
                     /gene="glmU"
                     /locus_tag="spr0891"
                     /EC_number="2.7.7.23"
                     /note="forms a homotrimer; catalyzes the acetylation of
                     glucosamine-1-phosphate and uridylation of
                     N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc;
                     function in cell wall synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional N-acetylglucosamine-1-phosphate
                     uridyltransferase/glucosamine-1-phosphate
                     acetyltransferase"
                     /protein_id="NP_358485.1"
                     /db_xref="GI:15902935"
                     /db_xref="GeneID:933167"
     gene            881755..882300
                     /locus_tag="spr0892"
                     /db_xref="GeneID:932911"
     CDS             881755..882300
                     /locus_tag="spr0892"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358486.1"
                     /db_xref="GI:15902936"
                     /db_xref="GeneID:932911"
     gene            882279..882626
                     /locus_tag="spr0893"
                     /db_xref="GeneID:933247"
     CDS             882279..882626
                     /locus_tag="spr0893"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358487.1"
                     /db_xref="GI:15902937"
                     /db_xref="GeneID:933247"
     gene            882643..883335
                     /gene="pfs"
                     /locus_tag="spr0894"
                     /db_xref="GeneID:933030"
     CDS             882643..883335
                     /gene="pfs"
                     /locus_tag="spr0894"
                     /EC_number="3.2.2.9"
                     /note="enables the cleavage of the glycosidic bond in both
                     5'-methylthioadenosine and S-adenosylhomocysteine"
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="NP_358488.1"
                     /db_xref="GI:15902938"
                     /db_xref="GeneID:933030"
     gene            883412..883903
                     /locus_tag="spr0895"
                     /db_xref="GeneID:932987"
     CDS             883412..883903
                     /locus_tag="spr0895"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358489.1"
                     /db_xref="GI:15902939"
                     /db_xref="GeneID:932987"
     gene            883965..884591
                     /gene="dnaQ"
                     /locus_tag="spr0896"
                     /db_xref="GeneID:934055"
     CDS             883965..884591
                     /gene="dnaQ"
                     /locus_tag="spr0896"
                     /EC_number="2.7.7.7"
                     /note="3'-5' exonuclease of DNA polymerase III"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="NP_358490.1"
                     /db_xref="GI:15902940"
                     /db_xref="GeneID:934055"
     gene            884594..886363
                     /locus_tag="spr0897"
                     /db_xref="GeneID:933351"
     CDS             884594..886363
                     /locus_tag="spr0897"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358491.1"
                     /db_xref="GI:15902941"
                     /db_xref="GeneID:933351"
     gene            886559..886974
                     /gene="transposase_A"
                     /locus_tag="spr0898"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933144"
     repeat_region   complement(887210..887308)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            887384..887584
                     /locus_tag="spr0900"
                     /db_xref="GeneID:933391"
     CDS             887384..887584
                     /locus_tag="spr0900"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358494.1"
                     /db_xref="GI:15902944"
                     /db_xref="GeneID:933391"
     gene            887626..888030
                     /locus_tag="spr0902"
                     /db_xref="GeneID:933860"
     CDS             887626..888030
                     /locus_tag="spr0902"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358496.1"
                     /db_xref="GI:15902946"
                     /db_xref="GeneID:933860"
     gene            888261..888968
                     /gene="ccdA"
                     /locus_tag="spr0903"
                     /db_xref="GeneID:934067"
     CDS             888261..888968
                     /gene="ccdA"
                     /locus_tag="spr0903"
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis protein"
                     /protein_id="NP_358497.1"
                     /db_xref="GI:15902947"
                     /db_xref="GeneID:934067"
     gene            888961..889536
                     /locus_tag="spr0904"
                     /db_xref="GeneID:933921"
     CDS             888961..889536
                     /locus_tag="spr0904"
                     /note="Similar to thiol:disulfide interchange protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358498.1"
                     /db_xref="GI:15902948"
                     /db_xref="GeneID:933921"
     gene            889898..891301
                     /gene="yfnA"
                     /locus_tag="spr0905"
                     /db_xref="GeneID:933721"
     CDS             889898..891301
                     /gene="yfnA"
                     /locus_tag="spr0905"
                     /codon_start=1
                     /transl_table=11
                     /product="cationic amino acid transporter"
                     /protein_id="NP_358499.1"
                     /db_xref="GI:15902949"
                     /db_xref="GeneID:933721"
     gene            891426..892361
                     /gene="lmb"
                     /locus_tag="spr0906"
                     /db_xref="GeneID:932947"
     CDS             891426..892361
                     /gene="lmb"
                     /locus_tag="spr0906"
                     /codon_start=1
                     /transl_table=11
                     /product="adhesion lipoprotein"
                     /protein_id="NP_358500.1"
                     /db_xref="GI:15902950"
                     /db_xref="GeneID:932947"
     gene            892369..894930
                     /gene="phtD"
                     /locus_tag="spr0907"
                     /db_xref="GeneID:933304"
     CDS             892369..894930
                     /gene="phtD"
                     /locus_tag="spr0907"
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein D"
                     /protein_id="NP_358501.1"
                     /db_xref="GI:15902951"
                     /db_xref="GeneID:933304"
     gene            895140..898259
                     /gene="phtE"
                     /locus_tag="spr0908"
                     /db_xref="GeneID:933256"
     CDS             895140..898259
                     /gene="phtE"
                     /locus_tag="spr0908"
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein E"
                     /protein_id="NP_358502.1"
                     /db_xref="GI:15902952"
                     /db_xref="GeneID:933256"
     gene            899089..899811
                     /locus_tag="spr0909"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934049"
     gene            900059..900688
                     /locus_tag="spr0912"
                     /db_xref="GeneID:933755"
     CDS             900059..900688
                     /locus_tag="spr0912"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358506.1"
                     /db_xref="GI:15902956"
                     /db_xref="GeneID:933755"
     gene            complement(900731..901951)
                     /gene="pepT"
                     /locus_tag="spr0913"
                     /db_xref="GeneID:933013"
     CDS             complement(900731..901951)
                     /gene="pepT"
                     /locus_tag="spr0913"
                     /EC_number="3.4.11.4"
                     /note="catalyzes the release of the N-terminal amino acid
                     from a tripeptide"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="NP_358507.1"
                     /db_xref="GI:15902957"
                     /db_xref="GeneID:933013"
     gene            902106..903200
                     /gene="hemH"
                     /locus_tag="spr0914"
                     /db_xref="GeneID:933500"
     CDS             902106..903200
                     /gene="hemH"
                     /locus_tag="spr0914"
                     /EC_number="4.99.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="NP_358508.1"
                     /db_xref="GI:15902958"
                     /db_xref="GeneID:933500"
     gene            complement(903242..903619)
                     /gene="mscL"
                     /locus_tag="spr0915"
                     /db_xref="GeneID:932884"
     CDS             complement(903242..903619)
                     /gene="mscL"
                     /locus_tag="spr0915"
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="NP_358509.1"
                     /db_xref="GI:15902959"
                     /db_xref="GeneID:932884"
     gene            complement(903701..904132)
                     /gene="mesH"
                     /locus_tag="spr0916"
                     /db_xref="GeneID:934062"
     CDS             complement(903701..904132)
                     /gene="mesH"
                     /locus_tag="spr0916"
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="NP_358510.1"
                     /db_xref="GI:15902960"
                     /db_xref="GeneID:934062"
     gene            904183..904764
                     /gene="ccl"
                     /locus_tag="spr0917"
                     /db_xref="GeneID:932932"
     CDS             904183..904764
                     /gene="ccl"
                     /locus_tag="spr0917"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358511.1"
                     /db_xref="GI:15902961"
                     /db_xref="GeneID:932932"
     gene            904864..904936
                     /gene="tRNA-Thr1"
                     /locus_tag="sprt07"
                     /db_xref="GeneID:933842"
     tRNA            904864..904936
                     /gene="tRNA-Thr1"
                     /locus_tag="sprt07"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:933842"
     gene            905279..906355
                     /gene="asd"
                     /locus_tag="spr0918"
                     /db_xref="GeneID:933797"
     CDS             905279..906355
                     /gene="asd"
                     /locus_tag="spr0918"
                     /EC_number="1.2.1.11"
                     /note="catalyzes the formation of 4-aspartyl phosphate
                     from aspartate 4-semialdehyde"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="NP_358512.1"
                     /db_xref="GI:15902962"
                     /db_xref="GeneID:933797"
     gene            906411..907346
                     /gene="dapA"
                     /locus_tag="spr0919"
                     /db_xref="GeneID:932822"
     CDS             906411..907346
                     /gene="dapA"
                     /locus_tag="spr0919"
                     /note="catalyzes the formation of dihydrodipicolinate from
                     L-aspartate 4-semialdehyde and pyruvate in lysine and
                     diaminopimelate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase"
                     /protein_id="NP_358513.1"
                     /db_xref="GI:15902963"
                     /db_xref="GeneID:932822"
     gene            complement(907393..908766)
                     /gene="trmE"
                     /locus_tag="spr0920"
                     /gene_synonym="mnmE; thdF"
                     /db_xref="GeneID:933044"
     CDS             complement(907393..908766)
                     /gene="trmE"
                     /locus_tag="spr0920"
                     /gene_synonym="mnmE; thdF"
                     /note="in Escherichia coli this protein is involved in the
                     biosynthesis of the hypermodified nucleoside
                     5-methylaminomethyl-2-thiouridine, which is found in the
                     wobble position of some tRNAs and affects ribosomal
                     frameshifting; shows potassium-dependent dimerization and
                     GTP hydrolysis; also involved in regulation of
                     glutamate-dependent acid resistance and activation of
                     gadE"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA modification GTPase TrmE"
                     /protein_id="NP_358514.2"
                     /db_xref="GI:161410748"
                     /db_xref="GeneID:933044"
     gene            complement(908903..909085)
                     /gene="xylH"
                     /locus_tag="spr0921"
                     /db_xref="GeneID:933810"
     CDS             complement(908903..909085)
                     /gene="xylH"
                     /locus_tag="spr0921"
                     /EC_number="5.3.2.-"
                     /note="4-OT; member of subfamily 5; forms a dimer; the
                     function in the Escherichia coli cell is unknown"
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="NP_358515.1"
                     /db_xref="GI:15902965"
                     /db_xref="GeneID:933810"
     gene            909208..909807
                     /gene="tdk"
                     /locus_tag="spr0922"
                     /db_xref="GeneID:933593"
     CDS             909208..909807
                     /gene="tdk"
                     /locus_tag="spr0922"
                     /EC_number="2.7.1.21"
                     /note="catalyzes the formation of thymidine 5'-phosphate
                     from thymidine"
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="NP_358516.1"
                     /db_xref="GI:15902966"
                     /db_xref="GeneID:933593"
     gene            909797..910276
                     /gene="bltD"
                     /locus_tag="spr0923"
                     /db_xref="GeneID:933780"
     CDS             909797..910276
                     /gene="bltD"
                     /locus_tag="spr0923"
                     /EC_number="2.3.1.57"
                     /codon_start=1
                     /transl_table=11
                     /product="spermine/spermidine acetyltransferase"
                     /protein_id="NP_358517.1"
                     /db_xref="GI:15902967"
                     /db_xref="GeneID:933780"
     gene            910286..911365
                     /gene="prfA"
                     /locus_tag="spr0924"
                     /db_xref="GeneID:933019"
     CDS             910286..911365
                     /gene="prfA"
                     /locus_tag="spr0924"
                     /note="recognizes the termination signals UAG and UAA
                     during protein translation a specificity which is
                     dependent on amino acid residues residing in loops of the
                     L-shaped tRNA-like molecule of RF1; this protein is
                     similar to release factor 2"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="NP_358518.1"
                     /db_xref="GI:15902968"
                     /db_xref="GeneID:933019"
     gene            911365..912204
                     /gene="hemK"
                     /locus_tag="spr0925"
                     /db_xref="GeneID:933764"
     CDS             911365..912204
                     /gene="hemK"
                     /locus_tag="spr0925"
                     /codon_start=1
                     /transl_table=11
                     /product="HemK protein"
                     /protein_id="NP_358519.1"
                     /db_xref="GI:15902969"
                     /db_xref="GeneID:933764"
     gene            912179..912790
                     /locus_tag="spr0926"
                     /db_xref="GeneID:933346"
     CDS             912179..912790
                     /locus_tag="spr0926"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358520.1"
                     /db_xref="GI:15902970"
                     /db_xref="GeneID:933346"
     gene            912753..913223
                     /locus_tag="spr0927"
                     /db_xref="GeneID:933156"
     CDS             912753..913223
                     /locus_tag="spr0927"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358521.1"
                     /db_xref="GI:15902971"
                     /db_xref="GeneID:933156"
     gene            913285..914541
                     /gene="glyA"
                     /locus_tag="spr0928"
                     /db_xref="GeneID:933588"
     CDS             913285..914541
                     /gene="glyA"
                     /locus_tag="spr0928"
                     /EC_number="2.1.2.1"
                     /note="catalyzes the reaction of glycine with
                     5,10-methylenetetrahydrofolate to form L-serine and
                     tetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="NP_358522.1"
                     /db_xref="GI:15902972"
                     /db_xref="GeneID:933588"
     gene            914516..915523
                     /locus_tag="spr0929"
                     /db_xref="GeneID:933203"
     CDS             914516..915523
                     /locus_tag="spr0929"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358523.1"
                     /db_xref="GI:15902973"
                     /db_xref="GeneID:933203"
     gene            915523..916137
                     /locus_tag="spr0930"
                     /db_xref="GeneID:933699"
     CDS             915523..916137
                     /locus_tag="spr0930"
                     /note="RAS-related protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358524.1"
                     /db_xref="GI:15902974"
                     /db_xref="GeneID:933699"
     gene            916211..917185
                     /locus_tag="spr0931"
                     /db_xref="GeneID:933174"
     CDS             916211..917185
                     /locus_tag="spr0931"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358525.1"
                     /db_xref="GI:15902975"
                     /db_xref="GeneID:933174"
     gene            917259..918890
                     /locus_tag="spr0932"
                     /db_xref="GeneID:933763"
     CDS             917259..918890
                     /locus_tag="spr0932"
                     /note="Similar to RNA methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358526.1"
                     /db_xref="GI:15902976"
                     /db_xref="GeneID:933763"
     gene            919089..919382
                     /locus_tag="spr0932a"
                     /db_xref="GeneID:17374508"
     CDS             919089..919382
                     /locus_tag="spr0932a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719803.1"
                     /db_xref="GI:555247349"
                     /db_xref="GeneID:17374508"
     gene            919628..919846
                     /locus_tag="spr0933"
                     /db_xref="GeneID:933497"
     CDS             919628..919846
                     /locus_tag="spr0933"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358527.1"
                     /db_xref="GI:15902977"
                     /db_xref="GeneID:933497"
     gene            920239..921264
                     /gene="ABC-SBP"
                     /locus_tag="spr0934"
                     /db_xref="GeneID:933737"
     CDS             920239..921264
                     /gene="ABC-SBP"
                     /locus_tag="spr0934"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358528.1"
                     /db_xref="GI:15902978"
                     /db_xref="GeneID:933737"
     gene            921242..922261
                     /gene="ABC-MSP"
                     /locus_tag="spr0935"
                     /db_xref="GeneID:932842"
     CDS             921242..922261
                     /gene="ABC-MSP"
                     /locus_tag="spr0935"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter permease"
                     /protein_id="NP_358529.1"
                     /db_xref="GI:15902979"
                     /db_xref="GeneID:932842"
     gene            922261..923268
                     /gene="ABC-MSP"
                     /locus_tag="spr0936"
                     /db_xref="GeneID:933342"
     CDS             922261..923268
                     /gene="ABC-MSP"
                     /locus_tag="spr0936"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter permease"
                     /protein_id="NP_358530.1"
                     /db_xref="GI:15902980"
                     /db_xref="GeneID:933342"
     gene            923268..924062
                     /gene="ABC-NBD"
                     /locus_tag="spr0938"
                     /db_xref="GeneID:933605"
     CDS             923268..924062
                     /gene="ABC-NBD"
                     /locus_tag="spr0938"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter ATP-binding
                     protein"
                     /protein_id="NP_358532.1"
                     /db_xref="GI:15902982"
                     /db_xref="GeneID:933605"
     gene            924630..924839
                     /locus_tag="spr0939"
                     /db_xref="GeneID:933248"
     CDS             924630..924839
                     /locus_tag="spr0939"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358533.1"
                     /db_xref="GI:15902983"
                     /db_xref="GeneID:933248"
     gene            924964..925119
                     /locus_tag="spr0940"
                     /db_xref="GeneID:933805"
     CDS             924964..925119
                     /locus_tag="spr0940"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358534.1"
                     /db_xref="GI:15902984"
                     /db_xref="GeneID:933805"
     gene            925803..925964
                     /locus_tag="spr0941"
                     /db_xref="GeneID:933415"
     CDS             925803..925964
                     /locus_tag="spr0941"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358535.1"
                     /db_xref="GI:15902985"
                     /db_xref="GeneID:933415"
     gene            926056..927735
                     /gene="ccrB"
                     /locus_tag="spr0942"
                     /db_xref="GeneID:933208"
     CDS             926056..927735
                     /gene="ccrB"
                     /locus_tag="spr0942"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358536.1"
                     /db_xref="GI:15902986"
                     /db_xref="GeneID:933208"
     gene            927958..928569
                     /locus_tag="spr0943"
                     /db_xref="GeneID:934059"
     CDS             927958..928569
                     /locus_tag="spr0943"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358537.1"
                     /db_xref="GI:15902987"
                     /db_xref="GeneID:934059"
     gene            928891..929116
                     /locus_tag="spr0944"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933201"
     gene            929141..929956
                     /locus_tag="spr0945"
                     /db_xref="GeneID:933843"
     CDS             929141..929956
                     /locus_tag="spr0945"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358539.1"
                     /db_xref="GI:15902989"
                     /db_xref="GeneID:933843"
     gene            929956..930810
                     /locus_tag="spr0946"
                     /db_xref="GeneID:933884"
     CDS             929956..930810
                     /locus_tag="spr0946"
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="NP_358540.1"
                     /db_xref="GI:15902990"
                     /db_xref="GeneID:933884"
     gene            930871..931806
                     /locus_tag="spr0947"
                     /db_xref="GeneID:933202"
     CDS             930871..931806
                     /locus_tag="spr0947"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358541.1"
                     /db_xref="GI:15902991"
                     /db_xref="GeneID:933202"
     gene            931945..933708
                     /gene="nplT"
                     /locus_tag="spr0948"
                     /db_xref="GeneID:933869"
     CDS             931945..933708
                     /gene="nplT"
                     /locus_tag="spr0948"
                     /EC_number="3.2.1.135"
                     /codon_start=1
                     /transl_table=11
                     /product="neopullulanase"
                     /protein_id="NP_358542.1"
                     /db_xref="GI:15902992"
                     /db_xref="GeneID:933869"
     gene            933794..934438
                     /locus_tag="spr0949"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933296"
     gene            934826..935359
                     /locus_tag="spr0951"
                     /db_xref="GeneID:932930"
     CDS             934826..935359
                     /locus_tag="spr0951"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_358545.1"
                     /db_xref="GI:15902995"
                     /db_xref="GeneID:932930"
     gene            935359..936120
                     /locus_tag="spr0952"
                     /db_xref="GeneID:932821"
     CDS             935359..936120
                     /locus_tag="spr0952"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358546.1"
                     /db_xref="GI:15902996"
                     /db_xref="GeneID:932821"
     gene            936148..937304
                     /locus_tag="spr0953"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933964"
     gene            938136..938495
                     /locus_tag="spr0955"
                     /db_xref="GeneID:932940"
     CDS             938136..938495
                     /locus_tag="spr0955"
                     /note="Hypothetical protein in TN5252"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn5252, ORF 10 protein"
                     /protein_id="NP_358549.1"
                     /db_xref="GI:15902999"
                     /db_xref="GeneID:932940"
     gene            938505..938834
                     /locus_tag="spr0956"
                     /db_xref="GeneID:933068"
     CDS             938505..938834
                     /locus_tag="spr0956"
                     /codon_start=1
                     /transl_table=11
                     /product="Tn5252, ORF 9 protein"
                     /protein_id="NP_358550.1"
                     /db_xref="GI:15903000"
                     /db_xref="GeneID:933068"
     gene            938857..940062
                     /gene="relaxase-truncation"
                     /locus_tag="spr0957"
                     /pseudogene="unknown"
                     /db_xref="GeneID:932923"
     gene            940146..940742
                     /locus_tag="spr0959"
                     /db_xref="GeneID:933242"
     CDS             940146..940742
                     /locus_tag="spr0959"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358553.1"
                     /db_xref="GI:15903003"
                     /db_xref="GeneID:933242"
     gene            complement(940787..941641)
                     /gene="mutR"
                     /locus_tag="spr0960"
                     /db_xref="GeneID:933784"
     CDS             complement(940787..941641)
                     /gene="mutR"
                     /locus_tag="spr0960"
                     /codon_start=1
                     /transl_table=11
                     /product="positive transcriptional regulator MutR"
                     /protein_id="NP_358554.1"
                     /db_xref="GI:15903004"
                     /db_xref="GeneID:933784"
     gene            941893..943188
                     /gene="rffD"
                     /locus_tag="spr0961"
                     /db_xref="GeneID:933215"
     CDS             941893..943188
                     /gene="rffD"
                     /locus_tag="spr0961"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosaminuronic acid
                     dehydrogenase"
                     /protein_id="NP_358555.1"
                     /db_xref="GI:15903005"
                     /db_xref="GeneID:933215"
     gene            943148..943798
                     /locus_tag="spr0962"
                     /db_xref="GeneID:933584"
     CDS             943148..943798
                     /locus_tag="spr0962"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358556.1"
                     /db_xref="GI:15903006"
                     /db_xref="GeneID:933584"
     gene            943808..944590
                     /locus_tag="spr0963"
                     /db_xref="GeneID:933374"
     CDS             943808..944590
                     /locus_tag="spr0963"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358557.1"
                     /db_xref="GI:15903007"
                     /db_xref="GeneID:933374"
     gene            944613..946505
                     /locus_tag="spr0964"
                     /db_xref="GeneID:933298"
     CDS             944613..946505
                     /locus_tag="spr0964"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358558.1"
                     /db_xref="GI:15903008"
                     /db_xref="GeneID:933298"
     gene            946534..947640
                     /locus_tag="spr0965"
                     /db_xref="GeneID:934070"
     CDS             946534..947640
                     /locus_tag="spr0965"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358559.1"
                     /db_xref="GI:15903009"
                     /db_xref="GeneID:934070"
     gene            947648..948958
                     /locus_tag="spr0966"
                     /db_xref="GeneID:933093"
     CDS             947648..948958
                     /locus_tag="spr0966"
                     /note="Probable acid-CoA ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358560.1"
                     /db_xref="GI:15903010"
                     /db_xref="GeneID:933093"
     gene            948960..950183
                     /locus_tag="spr0967"
                     /db_xref="GeneID:933966"
     CDS             948960..950183
                     /locus_tag="spr0967"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358561.1"
                     /db_xref="GI:15903011"
                     /db_xref="GeneID:933966"
     gene            950173..951123
                     /locus_tag="spr0968"
                     /db_xref="GeneID:933230"
     CDS             950173..951123
                     /locus_tag="spr0968"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358562.1"
                     /db_xref="GI:15903012"
                     /db_xref="GeneID:933230"
     gene            951138..952337
                     /gene="nikS"
                     /locus_tag="spr0969"
                     /db_xref="GeneID:933819"
     CDS             951138..952337
                     /gene="nikS"
                     /locus_tag="spr0969"
                     /codon_start=1
                     /transl_table=11
                     /product="nikkomycin biosynthesis protein, carboxylase"
                     /protein_id="NP_358563.1"
                     /db_xref="GI:15903013"
                     /db_xref="GeneID:933819"
     gene            952356..953000
                     /locus_tag="spr0970"
                     /db_xref="GeneID:933493"
     CDS             952356..953000
                     /locus_tag="spr0970"
                     /note="Probable acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358564.1"
                     /db_xref="GI:15903014"
                     /db_xref="GeneID:933493"
     gene            953383..954594
                     /gene="mefE"
                     /locus_tag="spr0971"
                     /db_xref="GeneID:933922"
     CDS             953383..954594
                     /gene="mefE"
                     /locus_tag="spr0971"
                     /codon_start=1
                     /transl_table=11
                     /product="macolide ABC transporter permease"
                     /protein_id="NP_358565.1"
                     /db_xref="GI:15903015"
                     /db_xref="GeneID:933922"
     gene            955253..955474
                     /locus_tag="spr0972"
                     /db_xref="GeneID:933427"
     CDS             955253..955474
                     /locus_tag="spr0972"
                     /note="repressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358566.1"
                     /db_xref="GI:15903016"
                     /db_xref="GeneID:933427"
     gene            956376..957605
                     /gene="ftsW"
                     /locus_tag="spr0973"
                     /db_xref="GeneID:933970"
     CDS             956376..957605
                     /gene="ftsW"
                     /locus_tag="spr0973"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="NP_358567.1"
                     /db_xref="GI:15903017"
                     /db_xref="GeneID:933970"
     gene            957625..960321
                     /gene="ppc"
                     /locus_tag="spr0974"
                     /db_xref="GeneID:932953"
     CDS             957625..960321
                     /gene="ppc"
                     /locus_tag="spr0974"
                     /EC_number="4.1.1.31"
                     /note="catalyzes the formation of oxaloacetate from
                     phosphoenolpyruvate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="NP_358568.1"
                     /db_xref="GI:15903018"
                     /db_xref="GeneID:932953"
     gene            960704..961738
                     /gene="ABC-SBP"
                     /locus_tag="spr0975"
                     /db_xref="GeneID:933181"
     CDS             960704..961738
                     /gene="ABC-SBP"
                     /locus_tag="spr0975"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358569.1"
                     /db_xref="GI:15903019"
                     /db_xref="GeneID:933181"
     gene            961807..962673
                     /gene="ABC-MSP"
                     /locus_tag="spr0976"
                     /db_xref="GeneID:933290"
     CDS             961807..962673
                     /gene="ABC-MSP"
                     /locus_tag="spr0976"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_358570.1"
                     /db_xref="GI:15903020"
                     /db_xref="GeneID:933290"
     gene            962670..963428
                     /gene="ABC-NBD"
                     /locus_tag="spr0977"
                     /db_xref="GeneID:933967"
     CDS             962670..963428
                     /gene="ABC-NBD"
                     /locus_tag="spr0977"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358571.1"
                     /db_xref="GI:15903021"
                     /db_xref="GeneID:933967"
     gene            963503..965278
                     /gene="dnaG"
                     /locus_tag="spr0978"
                     /db_xref="GeneID:933419"
     CDS             963503..965278
                     /gene="dnaG"
                     /locus_tag="spr0978"
                     /EC_number="2.7.7.-"
                     /note="synthesizes RNA primers at the replication forks"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="NP_358572.1"
                     /db_xref="GI:15903022"
                     /db_xref="GeneID:933419"
     gene            965281..966390
                     /gene="rpoD"
                     /locus_tag="spr0979"
                     /db_xref="GeneID:933267"
     CDS             965281..966390
                     /gene="rpoD"
                     /locus_tag="spr0979"
                     /note="sigma factors are initiation factors that promote
                     the attachment of RNA polymerase to specific initiation
                     sites and are then released; primary sigma factor of
                     bacterium"
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="NP_358573.1"
                     /db_xref="GI:15903023"
                     /db_xref="GeneID:933267"
     gene            966371..966733
                     /locus_tag="spr0980"
                     /db_xref="GeneID:933232"
     CDS             966371..966733
                     /locus_tag="spr0980"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358574.1"
                     /db_xref="GI:15903024"
                     /db_xref="GeneID:933232"
     gene            966767..967891
                     /gene="cpoA"
                     /locus_tag="spr0981"
                     /db_xref="GeneID:933377"
     CDS             966767..967891
                     /gene="cpoA"
                     /locus_tag="spr0981"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase CpoA"
                     /protein_id="NP_358575.1"
                     /db_xref="GI:15903025"
                     /db_xref="GeneID:933377"
     gene            967907..969232
                     /locus_tag="spr0982"
                     /db_xref="GeneID:932928"
     CDS             967907..969232
                     /locus_tag="spr0982"
                     /note="Probable hexosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="NP_358576.1"
                     /db_xref="GI:15903026"
                     /db_xref="GeneID:932928"
     gene            969263..969439
                     /locus_tag="spr0983"
                     /db_xref="GeneID:933885"
     CDS             969263..969439
                     /locus_tag="spr0983"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358577.1"
                     /db_xref="GI:15903027"
                     /db_xref="GeneID:933885"
     gene            969702..971006
                     /gene="obgE"
                     /locus_tag="spr0984"
                     /gene_synonym="cgtA; obg; yhbZ"
                     /db_xref="GeneID:933276"
     CDS             969702..971006
                     /gene="obgE"
                     /locus_tag="spr0984"
                     /gene_synonym="cgtA; obg; yhbZ"
                     /note="essential GTPase; exhibits high exchange rate for
                     GTP/GDP; associates with 50S ribosomal subunit; involved
                     in regulation of chromosomal replication"
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="NP_358578.2"
                     /db_xref="GI:161410747"
                     /db_xref="GeneID:933276"
     gene            971016..971174
                     /locus_tag="spr0985"
                     /db_xref="GeneID:933219"
     CDS             971016..971174
                     /locus_tag="spr0985"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358579.1"
                     /db_xref="GI:15903029"
                     /db_xref="GeneID:933219"
     gene            complement(972009..972563)
                     /gene="IS1167"
                     /locus_tag="spr0988"
                     /db_xref="GeneID:932860"
     CDS             complement(972009..972563)
                     /gene="IS1167"
                     /locus_tag="spr0988"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358582.1"
                     /db_xref="GI:15903032"
                     /db_xref="GeneID:932860"
     repeat_region   complement(972743..972849)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   973508..973659
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            973796..975055
                     /gene="murZ"
                     /locus_tag="spr0989"
                     /db_xref="GeneID:933272"
     CDS             973796..975055
                     /gene="murZ"
                     /locus_tag="spr0989"
                     /EC_number="2.5.1.7"
                     /note="adds enolpyruvyl to UDP-N-acetylglucosamine as a
                     component of cell wall formation; gram-positive bacteria
                     have 2 copies of MurA which are active"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="NP_358583.1"
                     /db_xref="GI:15903033"
                     /db_xref="GeneID:933272"
     gene            975065..975622
                     /locus_tag="spr0990"
                     /db_xref="GeneID:932825"
     CDS             975065..975622
                     /locus_tag="spr0990"
                     /note="Similar to alanine acetyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358584.1"
                     /db_xref="GI:15903034"
                     /db_xref="GeneID:932825"
     gene            975615..976892
                     /locus_tag="spr0991"
                     /db_xref="GeneID:933905"
     CDS             975615..976892
                     /locus_tag="spr0991"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358585.1"
                     /db_xref="GI:15903035"
                     /db_xref="GeneID:933905"
     gene            976908..977768
                     /gene="map"
                     /locus_tag="spr0992"
                     /db_xref="GeneID:932841"
     CDS             976908..977768
                     /gene="map"
                     /locus_tag="spr0992"
                     /EC_number="3.4.11.18"
                     /note="catalyzes the removal of N-terminal amino acids
                     from peptides and arylamides"
                     /codon_start=1
                     /transl_table=11
                     /product="methionine aminopeptidase"
                     /protein_id="NP_358586.1"
                     /db_xref="GI:15903036"
                     /db_xref="GeneID:932841"
     gene            977840..978547
                     /locus_tag="spr0993"
                     /db_xref="GeneID:933862"
     CDS             977840..978547
                     /locus_tag="spr0993"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358587.1"
                     /db_xref="GI:15903037"
                     /db_xref="GeneID:933862"
     gene            978562..978951
                     /gene="IS1381"
                     /locus_tag="spr0994"
                     /db_xref="GeneID:933283"
     CDS             978562..978951
                     /gene="IS1381"
                     /locus_tag="spr0994"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_358588.1"
                     /db_xref="GI:15903038"
                     /db_xref="GeneID:933283"
     gene            979142..981433
                     /gene="pcrA"
                     /locus_tag="spr0995"
                     /db_xref="GeneID:932805"
     CDS             979142..981433
                     /gene="pcrA"
                     /locus_tag="spr0995"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase PcrA"
                     /protein_id="NP_358589.1"
                     /db_xref="GI:15903039"
                     /db_xref="GeneID:932805"
     gene            981461..982156
                     /gene="radC"
                     /locus_tag="spr0996"
                     /db_xref="GeneID:934080"
     CDS             981461..982156
                     /gene="radC"
                     /locus_tag="spr0996"
                     /note="Involved in DNA double-strand break repair and
                     recombination. Promotes the annealing of complementary
                     single-stranded DNA and by simulation of RAD51
                     recombinase"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="NP_358590.1"
                     /db_xref="GI:15903040"
                     /db_xref="GeneID:934080"
     gene            complement(982153..982842)
                     /locus_tag="spr0997"
                     /db_xref="GeneID:934076"
     CDS             complement(982153..982842)
                     /locus_tag="spr0997"
                     /note="Probable amidotransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358591.1"
                     /db_xref="GI:15903041"
                     /db_xref="GeneID:934076"
     gene            complement(982860..983501)
                     /locus_tag="spr0998"
                     /db_xref="GeneID:934078"
     CDS             complement(982860..983501)
                     /locus_tag="spr0998"
                     /note="modulates transcription in response to the
                     NADH/NAD(+) redox state"
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="NP_358592.1"
                     /db_xref="GI:15903042"
                     /db_xref="GeneID:934078"
     gene            complement(983584..983835)
                     /locus_tag="spr0999"
                     /db_xref="GeneID:934167"
     CDS             complement(983584..983835)
                     /locus_tag="spr0999"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358593.1"
                     /db_xref="GI:15903043"
                     /db_xref="GeneID:934167"
     gene            complement(983807..984154)
                     /locus_tag="spr1000"
                     /db_xref="GeneID:934034"
     CDS             complement(983807..984154)
                     /locus_tag="spr1000"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358594.1"
                     /db_xref="GI:15903044"
                     /db_xref="GeneID:934034"
     gene            complement(984159..985274)
                     /gene="nifS"
                     /locus_tag="spr1001"
                     /db_xref="GeneID:934171"
     CDS             complement(984159..985274)
                     /gene="nifS"
                     /locus_tag="spr1001"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal-phosphate dependent aminotransferase"
                     /protein_id="NP_358595.1"
                     /db_xref="GI:15903045"
                     /db_xref="GeneID:934171"
     gene            complement(985284..986243)
                     /gene="prs"
                     /locus_tag="spr1002"
                     /db_xref="GeneID:932850"
     CDS             complement(985284..986243)
                     /gene="prs"
                     /locus_tag="spr1002"
                     /EC_number="2.7.6.1"
                     /note="catalyzes the formation of 5-phospho-alpha-D-ribose
                     1-phosphate from D-ribose 5-phosphate and ATP"
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate pyrophosphokinase"
                     /protein_id="NP_358596.1"
                     /db_xref="GI:15903046"
                     /db_xref="GeneID:932850"
     gene            complement(986356..986925)
                     /locus_tag="spr1003"
                     /db_xref="GeneID:934074"
     CDS             complement(986356..986925)
                     /locus_tag="spr1003"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358597.1"
                     /db_xref="GI:15903047"
                     /db_xref="GeneID:934074"
     gene            987053..987724
                     /locus_tag="spr1004"
                     /db_xref="GeneID:934631"
     CDS             987053..987724
                     /locus_tag="spr1004"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="NP_358598.1"
                     /db_xref="GI:15903048"
                     /db_xref="GeneID:934631"
     gene            987696..988526
                     /gene="ppnK"
                     /locus_tag="spr1005"
                     /db_xref="GeneID:934633"
     CDS             987696..988526
                     /gene="ppnK"
                     /locus_tag="spr1005"
                     /EC_number="2.7.1.23"
                     /note="catalyzes the phosphorylation of NAD to NADP"
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic polyphosphate/ATP-NAD kinase"
                     /protein_id="NP_358599.1"
                     /db_xref="GI:15903049"
                     /db_xref="GeneID:934633"
     gene            988523..989419
                     /gene="rluD"
                     /locus_tag="spr1006"
                     /db_xref="GeneID:933234"
     CDS             988523..989419
                     /gene="rluD"
                     /locus_tag="spr1006"
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine synthase"
                     /protein_id="NP_358600.1"
                     /db_xref="GI:15903050"
                     /db_xref="GeneID:933234"
     gene            989463..990437
                     /gene="eutD"
                     /locus_tag="spr1007"
                     /db_xref="GeneID:933854"
     CDS             989463..990437
                     /gene="eutD"
                     /locus_tag="spr1007"
                     /EC_number="2.3.1.8"
                     /note="in Salmonella this enzyme is required for
                     ethanolamine catabolism; has higher affinity for CoA than
                     Pta"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransacetylase"
                     /protein_id="NP_358601.1"
                     /db_xref="GI:15903051"
                     /db_xref="GeneID:933854"
     gene            complement(991498..992016)
                     /gene="IS1167"
                     /locus_tag="spr1009"
                     /db_xref="GeneID:933833"
     CDS             complement(991498..992016)
                     /gene="IS1167"
                     /locus_tag="spr1009"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358603.1"
                     /db_xref="GI:15903053"
                     /db_xref="GeneID:933833"
     gene            complement(992198..992497)
                     /locus_tag="spr1010"
                     /db_xref="GeneID:933771"
     CDS             complement(992198..992497)
                     /locus_tag="spr1010"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358604.1"
                     /db_xref="GI:15903054"
                     /db_xref="GeneID:933771"
     gene            992899..993603
                     /locus_tag="spr1011"
                     /db_xref="GeneID:933761"
     CDS             992899..993603
                     /locus_tag="spr1011"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358605.1"
                     /db_xref="GI:15903055"
                     /db_xref="GeneID:933761"
     gene            993785..994099
                     /gene="rplU"
                     /locus_tag="spr1012"
                     /db_xref="GeneID:933955"
     CDS             993785..994099
                     /gene="rplU"
                     /locus_tag="spr1012"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="NP_358606.1"
                     /db_xref="GI:15903056"
                     /db_xref="GeneID:933955"
     gene            994115..994459
                     /locus_tag="spr1013"
                     /db_xref="GeneID:933790"
     CDS             994115..994459
                     /locus_tag="spr1013"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358607.1"
                     /db_xref="GI:15903057"
                     /db_xref="GeneID:933790"
     gene            994500..994769
                     /gene="rpmA"
                     /locus_tag="spr1014"
                     /db_xref="GeneID:934115"
     CDS             994500..994769
                     /gene="rpmA"
                     /locus_tag="spr1014"
                     /note="involved in the peptidyltransferase reaction during
                     translation"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="NP_358608.1"
                     /db_xref="GI:15903058"
                     /db_xref="GeneID:934115"
     repeat_region   994913..995017
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     gene            995722..996639
                     /gene="mreA"
                     /locus_tag="spr1017"
                     /gene_synonym="ribC; ribF"
                     /db_xref="GeneID:934162"
     CDS             995722..996639
                     /gene="mreA"
                     /locus_tag="spr1017"
                     /gene_synonym="ribC; ribF"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /note="catalyzes the formation of FMN from riboflavin and
                     the formation of FAD from FMN; in Bacillus the ribC gene
                     has both flavokinase and FAD synthetase activities"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FMN
                     adenylyltransferase"
                     /protein_id="NP_358611.1"
                     /db_xref="GI:15903061"
                     /db_xref="GeneID:934162"
     gene            complement(996732..997580)
                     /locus_tag="spr1018"
                     /db_xref="GeneID:934083"
     CDS             complement(996732..997580)
                     /locus_tag="spr1018"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358612.1"
                     /db_xref="GI:15903062"
                     /db_xref="GeneID:934083"
     gene            997722..998561
                     /locus_tag="spr1019"
                     /db_xref="GeneID:934107"
     CDS             997722..998561
                     /locus_tag="spr1019"
                     /note="Similar to Bacillus subtilis DegV protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358613.1"
                     /db_xref="GI:15903063"
                     /db_xref="GeneID:934107"
     gene            998667..998942
                     /gene="hlpA"
                     /locus_tag="spr1020"
                     /db_xref="GeneID:934105"
     CDS             998667..998942
                     /gene="hlpA"
                     /locus_tag="spr1020"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU"
                     /protein_id="NP_358614.1"
                     /db_xref="GI:15903064"
                     /db_xref="GeneID:934105"
     repeat_region   999056..999162
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     gene            999368..1001269
                     /gene="ABC-NBD"
                     /locus_tag="spr1021"
                     /db_xref="GeneID:934100"
     CDS             999368..1001269
                     /gene="ABC-NBD"
                     /locus_tag="spr1021"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358615.1"
                     /db_xref="GI:15903065"
                     /db_xref="GeneID:934100"
     gene            1001242..1002135
                     /gene="rggD"
                     /locus_tag="spr1022"
                     /db_xref="GeneID:934159"
     CDS             1001242..1002135
                     /gene="rggD"
                     /locus_tag="spr1022"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MutR"
                     /protein_id="NP_358616.1"
                     /db_xref="GI:15903066"
                     /db_xref="GeneID:934159"
     gene            1002215..1003393
                     /gene="ABC-MSP"
                     /locus_tag="spr1023"
                     /db_xref="GeneID:932990"
     CDS             1002215..1003393
                     /gene="ABC-MSP"
                     /locus_tag="spr1023"
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter permease"
                     /protein_id="NP_358617.1"
                     /db_xref="GI:15903067"
                     /db_xref="GeneID:932990"
     gene            1003486..1005444
                     /gene="ligA"
                     /locus_tag="spr1024"
                     /db_xref="GeneID:933694"
     CDS             1003486..1005444
                     /gene="ligA"
                     /locus_tag="spr1024"
                     /EC_number="6.5.1.2"
                     /note="this protein catalyzes the formation of
                     phosphodiester linkages between 5'-phosphoryl and
                     3'-hydroxyl groups in double-stranded DNA using NAD as a
                     coenzyme and as the energy source for the reaction;
                     essential for DNA replication and repair of damaged DNA;
                     similar to ligase LigB"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="NP_358618.1"
                     /db_xref="GI:15903068"
                     /db_xref="GeneID:933694"
     gene            1005556..1007835
                     /gene="pulI"
                     /locus_tag="spr1025"
                     /db_xref="GeneID:932903"
     CDS             1005556..1007835
                     /gene="pulI"
                     /locus_tag="spr1025"
                     /EC_number="3.2.1.41"
                     /codon_start=1
                     /transl_table=11
                     /product="thermostable pullulanase"
                     /protein_id="NP_358619.1"
                     /db_xref="GI:15903069"
                     /db_xref="GeneID:932903"
     gene            1008379..1009803
                     /gene="gapN"
                     /locus_tag="spr1028"
                     /db_xref="GeneID:933338"
     CDS             1008379..1009803
                     /gene="gapN"
                     /locus_tag="spr1028"
                     /EC_number="1.2.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="NP_358622.1"
                     /db_xref="GI:15903072"
                     /db_xref="GeneID:933338"
     repeat_region   1009891..1009953
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   1009998..1010079
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_c"
     gene            1010268..1012196
                     /gene="glgB"
                     /locus_tag="spr1029"
                     /db_xref="GeneID:933336"
     CDS             1010268..1012196
                     /gene="glgB"
                     /locus_tag="spr1029"
                     /EC_number="2.4.1.18"
                     /note="catalyzes the transfer of a segment of a
                     1,4-alpha-D-glucan chain to a primary hydroxy group in a
                     similar glucan chain"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen branching protein"
                     /protein_id="NP_358623.1"
                     /db_xref="GI:15903073"
                     /db_xref="GeneID:933336"
     gene            1012186..1013328
                     /gene="glgC"
                     /locus_tag="spr1030"
                     /db_xref="GeneID:934106"
     CDS             1012186..1013328
                     /gene="glgC"
                     /locus_tag="spr1030"
                     /EC_number="2.7.7.27"
                     /note="catalyzes the formation of ADP-glucose and
                     diphosphate from ATP and alpha-D-glucose 1-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="NP_358624.1"
                     /db_xref="GI:15903074"
                     /db_xref="GeneID:934106"
     gene            1013318..1014457
                     /gene="glgD"
                     /locus_tag="spr1031"
                     /db_xref="GeneID:934104"
     CDS             1013318..1014457
                     /gene="glgD"
                     /locus_tag="spr1031"
                     /codon_start=1
                     /transl_table=11
                     /product="required for glycogen biosynthesis"
                     /protein_id="NP_358625.1"
                     /db_xref="GI:15903075"
                     /db_xref="GeneID:934104"
     gene            1014454..1015887
                     /gene="glgA"
                     /locus_tag="spr1032"
                     /db_xref="GeneID:934118"
     CDS             1014454..1015887
                     /gene="glgA"
                     /locus_tag="spr1032"
                     /EC_number="2.4.1.21"
                     /note="catalyzes the formation of alpha-1,4-glucan chains
                     from ADP-glucose"
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase"
                     /protein_id="NP_358626.1"
                     /db_xref="GI:15903076"
                     /db_xref="GeneID:934118"
     gene            1015946..1016591
                     /gene="serB-truncation"
                     /locus_tag="spr1033"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934110"
     gene            1016588..1017715
                     /gene="glxK"
                     /locus_tag="spr1034"
                     /db_xref="GeneID:934122"
     CDS             1016588..1017715
                     /gene="glxK"
                     /locus_tag="spr1034"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="NP_358628.1"
                     /db_xref="GI:15903078"
                     /db_xref="GeneID:934122"
     gene            complement(1017712..1018158)
                     /locus_tag="spr1035"
                     /db_xref="GeneID:934154"
     CDS             complement(1017712..1018158)
                     /locus_tag="spr1035"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358629.1"
                     /db_xref="GI:15903079"
                     /db_xref="GeneID:934154"
     gene            1018322..1019626
                     /gene="eno"
                     /locus_tag="spr1036"
                     /db_xref="GeneID:934109"
     CDS             1018322..1019626
                     /gene="eno"
                     /locus_tag="spr1036"
                     /EC_number="4.2.1.11"
                     /note="enolase; catalyzes the formation of
                     phosphoenolpyruvate from 2-phospho-D-glycerate in
                     glycolysis"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="NP_358630.1"
                     /db_xref="GI:15903080"
                     /db_xref="GeneID:934109"
     gene            complement(1020607..1020975)
                     /gene="transposase_A"
                     /locus_tag="spr1038"
                     /db_xref="GeneID:934125"
     CDS             complement(1020607..1020975)
                     /gene="transposase_A"
                     /locus_tag="spr1038"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358632.1"
                     /db_xref="GI:15903082"
                     /db_xref="GeneID:934125"
     repeat_region   complement(1021000..1021098)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            1021482..1024757
                     /gene="rexB"
                     /locus_tag="spr1039"
                     /db_xref="GeneID:933876"
     CDS             1021482..1024757
                     /gene="rexB"
                     /locus_tag="spr1039"
                     /codon_start=1
                     /transl_table=11
                     /product="second subunit of major exonuclease"
                     /protein_id="NP_358633.1"
                     /db_xref="GI:15903083"
                     /db_xref="GeneID:933876"
     gene            1024754..1028404
                     /gene="rexA"
                     /locus_tag="spr1040"
                     /db_xref="GeneID:933887"
     CDS             1024754..1028404
                     /gene="rexA"
                     /locus_tag="spr1040"
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease RexA"
                     /protein_id="NP_358634.1"
                     /db_xref="GI:15903084"
                     /db_xref="GeneID:933887"
     repeat_region   1028407..1028557
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            1028574..1029752
                     /locus_tag="spr1041"
                     /db_xref="GeneID:933976"
     CDS             1028574..1029752
                     /locus_tag="spr1041"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358635.1"
                     /db_xref="GI:15903085"
                     /db_xref="GeneID:933976"
     gene            1029961..1035852
                     /gene="iga"
                     /locus_tag="spr1042"
                     /db_xref="GeneID:933909"
     CDS             1029961..1035852
                     /gene="iga"
                     /locus_tag="spr1042"
                     /EC_number="3.4.24.13"
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin A1 protease"
                     /protein_id="NP_358636.1"
                     /db_xref="GI:15903086"
                     /db_xref="GeneID:933909"
     gene            1036311..1037162
                     /gene="rbgA"
                     /locus_tag="spr1043"
                     /gene_synonym="ylqF"
                     /db_xref="GeneID:933067"
     CDS             1036311..1037162
                     /gene="rbgA"
                     /locus_tag="spr1043"
                     /gene_synonym="ylqF"
                     /note="essential GTPase; functions in ribosome assembly;
                     binds a unique part of the 23S rRNA; interacts with
                     ribosomal protein L25(Ctc)"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal biogenesis GTPase"
                     /protein_id="NP_358637.1"
                     /db_xref="GI:15903087"
                     /db_xref="GeneID:933067"
     gene            1037149..1037928
                     /gene="rnhB"
                     /locus_tag="spr1044"
                     /db_xref="GeneID:933032"
     CDS             1037149..1037928
                     /gene="rnhB"
                     /locus_tag="spr1044"
                     /EC_number="3.1.26.4"
                     /note="RNH2; RNase HII; binds manganese; endonuclease
                     which specifically degrades the RNA of RNA-DNA hybrids"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="NP_358638.1"
                     /db_xref="GI:15903088"
                     /db_xref="GeneID:933032"
     gene            1037929..1039494
                     /locus_tag="spr1045"
                     /db_xref="GeneID:934627"
     CDS             1037929..1039494
                     /locus_tag="spr1045"
                     /note="channel transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="NP_358639.1"
                     /db_xref="GI:15903089"
                     /db_xref="GeneID:934627"
     repeat_region   complement(1039745..1039844)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            1040078..1041148
                     /gene="xerS"
                     /locus_tag="spr1046"
                     /db_xref="GeneID:934075"
     CDS             1040078..1041148
                     /gene="xerS"
                     /locus_tag="spr1046"
                     /note="site-specific tyrosine recombinase which cuts and
                     rejoins DNA molecules; binds cooperatively to specific DNA
                     consensus sites; essential to convert chromosome dimers to
                     monomers during cell division and functions during plasmid
                     segregation; cell division protein FtsK may regulate the
                     XerS"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerS"
                     /protein_id="NP_358640.1"
                     /db_xref="GI:15903090"
                     /db_xref="GeneID:934075"
     gene            complement(1041221..1042210)
                     /gene="lplA"
                     /locus_tag="spr1047"
                     /db_xref="GeneID:934072"
     CDS             complement(1041221..1042210)
                     /gene="lplA"
                     /locus_tag="spr1047"
                     /EC_number="6.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate-protein ligase"
                     /protein_id="NP_358641.1"
                     /db_xref="GI:15903091"
                     /db_xref="GeneID:934072"
     gene            complement(1042274..1043977)
                     /gene="acoL"
                     /locus_tag="spr1048"
                     /db_xref="GeneID:934625"
     CDS             complement(1042274..1043977)
                     /gene="acoL"
                     /locus_tag="spr1048"
                     /EC_number="1.8.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="NP_358642.1"
                     /db_xref="GI:15903092"
                     /db_xref="GeneID:934625"
     gene            complement(1044023..1045066)
                     /gene="acoC"
                     /locus_tag="spr1049"
                     /db_xref="GeneID:934073"
     CDS             complement(1044023..1045066)
                     /gene="acoC"
                     /locus_tag="spr1049"
                     /EC_number="2.3.1.12"
                     /note="unlike PdhC proteins from other organisms, some
                     Mycoplasma lack an N-terminal lipoyl domain; in Mycoplasma
                     hyopneumonia the PdhD proteins contains the lipoyl domain"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="NP_358643.2"
                     /db_xref="GI:161410746"
                     /db_xref="GeneID:934073"
     gene            complement(1045284..1046276)
                     /gene="acoB"
                     /locus_tag="spr1050"
                     /db_xref="GeneID:934165"
     CDS             complement(1045284..1046276)
                     /gene="acoB"
                     /locus_tag="spr1050"
                     /codon_start=1
                     /transl_table=11
                     /product="acetoin dehydrogenase, E1 component subunit
                     beta"
                     /protein_id="NP_358644.1"
                     /db_xref="GI:15903094"
                     /db_xref="GeneID:934165"
     gene            complement(1046292..1047260)
                     /gene="acoA"
                     /locus_tag="spr1051"
                     /db_xref="GeneID:934170"
     CDS             complement(1046292..1047260)
                     /gene="acoA"
                     /locus_tag="spr1051"
                     /codon_start=1
                     /transl_table=11
                     /product="TPP-dependent acetoin dehydrogenase subunit
                     alpha"
                     /protein_id="NP_358645.1"
                     /db_xref="GI:15903095"
                     /db_xref="GeneID:934170"
     gene            complement(1047414..1048775)
                     /locus_tag="spr1052"
                     /db_xref="GeneID:934077"
     CDS             complement(1047414..1048775)
                     /locus_tag="spr1052"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE efflux family protein"
                     /protein_id="NP_358646.1"
                     /db_xref="GI:15903096"
                     /db_xref="GeneID:934077"
     gene            complement(1049060..1050328)
                     /gene="pyrC"
                     /locus_tag="spr1053"
                     /db_xref="GeneID:934081"
     CDS             complement(1049060..1050328)
                     /gene="pyrC"
                     /locus_tag="spr1053"
                     /EC_number="3.5.2.3"
                     /note="catalyzes the formation of N-carbamoyl-L-aspartate
                     from (S)-dihydroorotate in pyrimidine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="NP_358647.1"
                     /db_xref="GI:15903097"
                     /db_xref="GeneID:934081"
     gene            complement(1050341..1050805)
                     /gene="mutX"
                     /locus_tag="spr1054"
                     /db_xref="GeneID:933037"
     CDS             complement(1050341..1050805)
                     /gene="mutX"
                     /locus_tag="spr1054"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxodGTP nucleoside triphosphatase"
                     /protein_id="NP_358648.1"
                     /db_xref="GI:15903098"
                     /db_xref="GeneID:933037"
     gene            complement(1050815..1051483)
                     /gene="ung"
                     /locus_tag="spr1055"
                     /db_xref="GeneID:933680"
     CDS             complement(1050815..1051483)
                     /gene="ung"
                     /locus_tag="spr1055"
                     /EC_number="3.2.2.-"
                     /note="Excises uracil residues from the DNA which can
                     arise as a result of misincorporation of dUMP residues by
                     DNA polymerase or due to deamination of cytosine"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="NP_358649.1"
                     /db_xref="GI:15903099"
                     /db_xref="GeneID:933680"
     gene            complement(1051604..1052251)
                     /locus_tag="spr1056"
                     /db_xref="GeneID:933471"
     CDS             complement(1051604..1052251)
                     /locus_tag="spr1056"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358650.1"
                     /db_xref="GI:15903100"
                     /db_xref="GeneID:933471"
     gene            complement(1052265..1052978)
                     /locus_tag="spr1057"
                     /db_xref="GeneID:932848"
     CDS             complement(1052265..1052978)
                     /locus_tag="spr1057"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358651.1"
                     /db_xref="GI:15903101"
                     /db_xref="GeneID:932848"
     gene            complement(1053436..1053816)
                     /locus_tag="spr1058"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933172"
     repeat_region   complement(1054055..1054126)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1054238..1056805)
                     /gene="phpA"
                     /locus_tag="spr1060"
                     /db_xref="GeneID:933226"
     CDS             complement(1054238..1056805)
                     /gene="phpA"
                     /locus_tag="spr1060"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine motif-containing protein"
                     /protein_id="NP_358654.1"
                     /db_xref="GI:15903104"
                     /db_xref="GeneID:933226"
     gene            complement(1056930..1059416)
                     /gene="phtA"
                     /locus_tag="spr1061"
                     /db_xref="GeneID:933846"
     CDS             complement(1056930..1059416)
                     /gene="phtA"
                     /locus_tag="spr1061"
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein A"
                     /protein_id="NP_358655.1"
                     /db_xref="GI:15903105"
                     /db_xref="GeneID:933846"
     gene            complement(1059635..1061368)
                     /gene="ptsI"
                     /locus_tag="spr1062"
                     /db_xref="GeneID:933754"
     CDS             complement(1059635..1061368)
                     /gene="ptsI"
                     /locus_tag="spr1062"
                     /EC_number="2.7.3.9"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase"
                     /protein_id="NP_358656.1"
                     /db_xref="GI:15903106"
                     /db_xref="GeneID:933754"
     gene            complement(1061374..1061637)
                     /gene="ptsH"
                     /locus_tag="spr1063"
                     /db_xref="GeneID:932807"
     CDS             complement(1061374..1061637)
                     /gene="ptsH"
                     /locus_tag="spr1063"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="NP_358657.1"
                     /db_xref="GI:15903107"
                     /db_xref="GeneID:932807"
     gene            1061970..1062206
                     /gene="nrdH"
                     /locus_tag="spr1064"
                     /db_xref="GeneID:933182"
     CDS             1061970..1062206
                     /gene="nrdH"
                     /locus_tag="spr1064"
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein"
                     /protein_id="NP_358658.1"
                     /db_xref="GI:15903108"
                     /db_xref="GeneID:933182"
     gene            1062287..1064446
                     /gene="nrdE"
                     /locus_tag="spr1065"
                     /db_xref="GeneID:933455"
     CDS             1062287..1064446
                     /gene="nrdE"
                     /locus_tag="spr1065"
                     /EC_number="1.17.4.1"
                     /note="Catalyzes the rate-limiting step in dNTP synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     alpha"
                     /protein_id="NP_358659.1"
                     /db_xref="GI:15903109"
                     /db_xref="GeneID:933455"
     gene            1064634..1065596
                     /gene="nrdF"
                     /locus_tag="spr1066"
                     /db_xref="GeneID:932802"
     CDS             1064634..1065596
                     /gene="nrdF"
                     /locus_tag="spr1066"
                     /EC_number="1.17.4.1"
                     /note="B2 or R2 protein; type 1b enzyme; catalyzes the
                     rate-limiting step in dNTP synthesis; converts nucleotides
                     to deoxynucleotides; forms a homodimer and then a
                     multimeric complex with NrdE"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="NP_358660.1"
                     /db_xref="GI:15903110"
                     /db_xref="GeneID:932802"
     gene            1065778..1066539
                     /gene="lacR"
                     /locus_tag="spr1067"
                     /db_xref="GeneID:932931"
     CDS             1065778..1066539
                     /gene="lacR"
                     /locus_tag="spr1067"
                     /codon_start=1
                     /transl_table=11
                     /product="lactose PTS system repressor"
                     /protein_id="NP_358661.1"
                     /db_xref="GI:15903111"
                     /db_xref="GeneID:932931"
     gene            complement(1067037..1068443)
                     /gene="lacG"
                     /locus_tag="spr1069"
                     /db_xref="GeneID:932827"
     CDS             complement(1067037..1068443)
                     /gene="lacG"
                     /locus_tag="spr1069"
                     /EC_number="3.2.1.85"
                     /note="catalyzes the formation of 6-phospho-galactose from
                     a 6-phospho-beta-galactoside"
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="NP_358662.1"
                     /db_xref="GI:15903112"
                     /db_xref="GeneID:932827"
     gene            complement(1068652..1070343)
                     /gene="lacE"
                     /locus_tag="spr1070"
                     /db_xref="GeneID:933773"
     CDS             complement(1068652..1070343)
                     /gene="lacE"
                     /locus_tag="spr1070"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system lactose-specific transporter subunit
                     IIBC"
                     /protein_id="NP_358663.1"
                     /db_xref="GI:15903113"
                     /db_xref="GeneID:933773"
     gene            complement(1070343..1070660)
                     /gene="lacF"
                     /locus_tag="spr1071"
                     /db_xref="GeneID:933794"
     CDS             complement(1070343..1070660)
                     /gene="lacF"
                     /locus_tag="spr1071"
                     /EC_number="2.7.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system lactose-specific transporter subunit
                     IIA"
                     /protein_id="NP_358664.1"
                     /db_xref="GI:15903114"
                     /db_xref="GeneID:933794"
     gene            complement(1070696..1071532)
                     /gene="lacT"
                     /locus_tag="spr1072"
                     /db_xref="GeneID:932881"
     CDS             complement(1070696..1071532)
                     /gene="lacT"
                     /locus_tag="spr1072"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator LacT"
                     /protein_id="NP_358665.1"
                     /db_xref="GI:15903115"
                     /db_xref="GeneID:932881"
     gene            complement(1071766..1072746)
                     /gene="lacD"
                     /locus_tag="spr1073"
                     /db_xref="GeneID:933800"
     CDS             complement(1071766..1072746)
                     /gene="lacD"
                     /locus_tag="spr1073"
                     /EC_number="4.1.2.40"
                     /note="catalyzes the reversible reaction of
                     dihydroxyacetone phosphate with glyceraldehyde 3-phosphate
                     to produce tagatose 1,6-bisphosphate; in Streptococcus
                     pyogenes there are two paralogs of tagatose-bisphosphate
                     aldolase, encoded by lacD1 and lacD2; expression of lacD1
                     is highly regulated by environmental conditions while
                     lacD2 specializes in an efficient utilization of
                     carbohydrate sources"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose 1,6-diphosphate aldolase"
                     /protein_id="NP_358666.1"
                     /db_xref="GI:15903116"
                     /db_xref="GeneID:933800"
     gene            complement(1072748..1073677)
                     /gene="lacC"
                     /locus_tag="spr1074"
                     /db_xref="GeneID:933209"
     CDS             complement(1072748..1073677)
                     /gene="lacC"
                     /locus_tag="spr1074"
                     /EC_number="2.7.1.144"
                     /note="catalyzes the formation of tagatose
                     1,6-bisphosphate from tagatose 6-phosphate and ATP"
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="NP_358667.1"
                     /db_xref="GI:15903117"
                     /db_xref="GeneID:933209"
     gene            complement(1073688..1074203)
                     /gene="lacB"
                     /locus_tag="spr1075"
                     /db_xref="GeneID:933958"
     CDS             complement(1073688..1074203)
                     /gene="lacB"
                     /locus_tag="spr1075"
                     /EC_number="5.3.1.26"
                     /note="catalyzes the interconversion of galactose
                     6-phosphate to tagatose 6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="NP_358668.1"
                     /db_xref="GI:15903118"
                     /db_xref="GeneID:933958"
     gene            complement(1074234..1074659)
                     /gene="lacA"
                     /locus_tag="spr1076"
                     /db_xref="GeneID:933185"
     CDS             complement(1074234..1074659)
                     /gene="lacA"
                     /locus_tag="spr1076"
                     /EC_number="5.3.1.26"
                     /note="catalyzes the interconversion of galactose
                     6-phosphate to tagatose 6-phosphate; tagatose pathway for
                     galactose utilization"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="NP_358669.1"
                     /db_xref="GI:15903119"
                     /db_xref="GeneID:933185"
     gene            complement(1075330..1075728)
                     /locus_tag="spr1078"
                     /db_xref="GeneID:933863"
     CDS             complement(1075330..1075728)
                     /locus_tag="spr1078"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358671.1"
                     /db_xref="GI:15903121"
                     /db_xref="GeneID:933863"
     gene            complement(1075659..1076180)
                     /locus_tag="spr1079"
                     /db_xref="GeneID:934030"
     CDS             complement(1075659..1076180)
                     /locus_tag="spr1079"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358672.1"
                     /db_xref="GI:15903122"
                     /db_xref="GeneID:934030"
     gene            complement(1076140..1076442)
                     /locus_tag="spr1080"
                     /db_xref="GeneID:933906"
     CDS             complement(1076140..1076442)
                     /locus_tag="spr1080"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358673.1"
                     /db_xref="GI:15903123"
                     /db_xref="GeneID:933906"
     gene            complement(1076480..1076752)
                     /locus_tag="spr1081"
                     /db_xref="GeneID:932942"
     CDS             complement(1076480..1076752)
                     /locus_tag="spr1081"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358674.1"
                     /db_xref="GI:15903124"
                     /db_xref="GeneID:932942"
     repeat_region   complement(1077128..1077278)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            1077136..1077288
                     /locus_tag="spr1079a"
                     /db_xref="GeneID:17374509"
     CDS             1077136..1077288
                     /locus_tag="spr1079a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719804.1"
                     /db_xref="GI:555247350"
                     /db_xref="GeneID:17374509"
     gene            complement(1077369..1079192)
                     /gene="lepA"
                     /locus_tag="spr1082"
                     /db_xref="GeneID:933087"
     CDS             complement(1077369..1079192)
                     /gene="lepA"
                     /locus_tag="spr1082"
                     /note="binds to the ribosome on the universally-conserved
                     alpha-sarcin loop"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein LepA"
                     /protein_id="NP_358675.1"
                     /db_xref="GI:15903125"
                     /db_xref="GeneID:933087"
     gene            complement(1079271..1079999)
                     /gene="pphA"
                     /locus_tag="spr1083"
                     /db_xref="GeneID:933792"
     CDS             complement(1079271..1079999)
                     /gene="pphA"
                     /locus_tag="spr1083"
                     /EC_number="3.1.3.16"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="NP_358676.1"
                     /db_xref="GI:15903126"
                     /db_xref="GeneID:933792"
     gene            complement(1080001..1081668)
                     /gene="recN"
                     /locus_tag="spr1084"
                     /db_xref="GeneID:934047"
     CDS             complement(1080001..1081668)
                     /gene="recN"
                     /locus_tag="spr1084"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="NP_358677.1"
                     /db_xref="GI:15903127"
                     /db_xref="GeneID:934047"
     gene            complement(1081675..1082106)
                     /gene="ahrC"
                     /locus_tag="spr1085"
                     /db_xref="GeneID:933785"
     CDS             complement(1081675..1082106)
                     /gene="ahrC"
                     /locus_tag="spr1085"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine metabolism transcriptional regulator"
                     /protein_id="NP_358678.1"
                     /db_xref="GI:15903128"
                     /db_xref="GeneID:933785"
     gene            complement(1082099..1082914)
                     /locus_tag="spr1086"
                     /db_xref="GeneID:933503"
     CDS             complement(1082099..1082914)
                     /locus_tag="spr1086"
                     /note="Hemolysin-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358679.1"
                     /db_xref="GI:15903129"
                     /db_xref="GeneID:933503"
     gene            complement(1082907..1083782)
                     /gene="ispA"
                     /locus_tag="spr1087"
                     /db_xref="GeneID:933371"
     CDS             complement(1082907..1083782)
                     /gene="ispA"
                     /locus_tag="spr1087"
                     /EC_number="2.5.1.10"
                     /codon_start=1
                     /transl_table=11
                     /product="geranyltranstransferase"
                     /protein_id="NP_358680.1"
                     /db_xref="GI:15903130"
                     /db_xref="GeneID:933371"
     gene            complement(1083779..1083991)
                     /gene="xseB"
                     /locus_tag="spr1088"
                     /db_xref="GeneID:933250"
     CDS             complement(1083779..1083991)
                     /gene="xseB"
                     /locus_tag="spr1088"
                     /EC_number="3.1.11.6"
                     /note="catalyzes the bidirectional exonucleolytic cleavage
                     of DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="NP_358681.1"
                     /db_xref="GI:15903131"
                     /db_xref="GeneID:933250"
     gene            complement(1083969..1085315)
                     /gene="xseA"
                     /locus_tag="spr1089"
                     /db_xref="GeneID:933134"
     CDS             complement(1083969..1085315)
                     /gene="xseA"
                     /locus_tag="spr1089"
                     /EC_number="3.1.11.6"
                     /note="bidirectionally degrades single-stranded DNA into
                     large acid-insoluble oligonucleotides"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="NP_358682.1"
                     /db_xref="GI:15903132"
                     /db_xref="GeneID:933134"
     gene            complement(1085437..1086075)
                     /gene="udK"
                     /locus_tag="spr1090"
                     /db_xref="GeneID:933122"
     CDS             complement(1085437..1086075)
                     /gene="udK"
                     /locus_tag="spr1090"
                     /EC_number="2.7.1.48"
                     /note="functions in pyrimidine salvage; pyrimidine
                     ribonucleoside kinase; phosphorylates nucleosides or
                     dinucleosides to make UMP or CMP using ATP or GTP as the
                     donor"
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="NP_358683.1"
                     /db_xref="GI:15903133"
                     /db_xref="GeneID:933122"
     gene            complement(1086183..1086485)
                     /locus_tag="spr1091"
                     /db_xref="GeneID:933148"
     CDS             complement(1086183..1086485)
                     /locus_tag="spr1091"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358684.1"
                     /db_xref="GI:15903134"
                     /db_xref="GeneID:933148"
     gene            complement(1086726..1087604)
                     /gene="truB"
                     /locus_tag="spr1092"
                     /db_xref="GeneID:933266"
     CDS             complement(1086726..1087604)
                     /gene="truB"
                     /locus_tag="spr1092"
                     /EC_number="4.2.1.70"
                     /note="catalyzes isomerization of specific uridines in RNA
                     to pseudouridine; responsible for residues in T loops of
                     many tRNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase B"
                     /protein_id="NP_358685.1"
                     /db_xref="GI:15903135"
                     /db_xref="GeneID:933266"
     gene            complement(1087705..1090890)
                     /locus_tag="spr1093"
                     /db_xref="GeneID:933791"
     CDS             complement(1087705..1090890)
                     /locus_tag="spr1093"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358686.1"
                     /db_xref="GI:15903136"
                     /db_xref="GeneID:933791"
     gene            complement(1090902..1092176)
                     /locus_tag="spr1094"
                     /db_xref="GeneID:933072"
     CDS             complement(1090902..1092176)
                     /locus_tag="spr1094"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358687.1"
                     /db_xref="GI:15903137"
                     /db_xref="GeneID:933072"
     gene            complement(1092272..1093531)
                     /gene="metY-truncation"
                     /locus_tag="spr1095"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933404"
     gene            complement(1093679..1094476)
                     /gene="nirC"
                     /locus_tag="spr1097"
                     /db_xref="GeneID:934032"
     CDS             complement(1093679..1094476)
                     /gene="nirC"
                     /locus_tag="spr1097"
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrate transporter"
                     /protein_id="NP_358690.1"
                     /db_xref="GI:15903140"
                     /db_xref="GeneID:934032"
     repeat_region   1094559..1094665
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1094720..1095463)
                     /gene="srtA"
                     /locus_tag="spr1098"
                     /db_xref="GeneID:933969"
     CDS             complement(1094720..1095463)
                     /gene="srtA"
                     /locus_tag="spr1098"
                     /note="proposed to perform the peptide cleavage and the
                     transpeptidation during the process of anchoring proteins
                     to Gram-positive bacterial cell walls"
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="NP_358691.1"
                     /db_xref="GI:15903141"
                     /db_xref="GeneID:933969"
     gene            complement(1095463..1097931)
                     /gene="gyrA"
                     /locus_tag="spr1099"
                     /db_xref="GeneID:933198"
     CDS             complement(1095463..1097931)
                     /gene="gyrA"
                     /locus_tag="spr1099"
                     /EC_number="5.99.1.3"
                     /note="negatively supercoils closed circular
                     double-stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="NP_358692.1"
                     /db_xref="GI:15903142"
                     /db_xref="GeneID:933198"
     gene            1098125..1099111
                     /gene="ldh"
                     /locus_tag="spr1100"
                     /db_xref="GeneID:933245"
     CDS             1098125..1099111
                     /gene="ldh"
                     /locus_tag="spr1100"
                     /EC_number="1.1.1.27"
                     /note="Converts (S)-lactate and NAD(+) to pyruvate and
                     NADH"
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="NP_358693.1"
                     /db_xref="GI:15903143"
                     /db_xref="GeneID:933245"
     repeat_region   1099245..1099335
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            complement(1099497..1102751)
                     /gene="spnII-interrupted-C"
                     /locus_tag="spr1101"
                     /db_xref="GeneID:933928"
     CDS             complement(1099497..1102751)
                     /gene="spnII-interrupted-C"
                     /locus_tag="spr1101"
                     /EC_number="3.1.21.4"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="NP_358694.1"
                     /db_xref="GI:15903144"
                     /db_xref="REBASE:SpnRORF1101P"
                     /db_xref="GeneID:933928"
     gene            complement(1102916..1104793)
                     /gene="spnII-interrupted-N"
                     /locus_tag="spr1102"
                     /db_xref="GeneID:933783"
     CDS             complement(1102916..1104793)
                     /gene="spnII-interrupted-N"
                     /locus_tag="spr1102"
                     /EC_number="3.1.21.4"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="NP_358695.1"
                     /db_xref="GI:15903145"
                     /db_xref="REBASE:SpnRORF1101P"
                     /db_xref="GeneID:933783"
     gene            complement(1104862..1105125)
                     /locus_tag="spr1103"
                     /db_xref="GeneID:933412"
     CDS             complement(1104862..1105125)
                     /locus_tag="spr1103"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358696.1"
                     /db_xref="GI:15903146"
                     /db_xref="GeneID:933412"
     gene            complement(1105118..1105420)
                     /locus_tag="spr1104"
                     /db_xref="GeneID:933121"
     CDS             complement(1105118..1105420)
                     /locus_tag="spr1104"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358697.1"
                     /db_xref="GI:15903147"
                     /db_xref="GeneID:933121"
     gene            complement(1105451..1106260)
                     /gene="vicX"
                     /locus_tag="spr1105"
                     /db_xref="GeneID:933337"
     CDS             complement(1105451..1106260)
                     /gene="vicX"
                     /locus_tag="spr1105"
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="NP_358698.1"
                     /db_xref="GI:15903148"
                     /db_xref="GeneID:933337"
     gene            complement(1106262..1107611)
                     /gene="hk02"
                     /locus_tag="spr1106"
                     /db_xref="GeneID:933765"
     CDS             complement(1106262..1107611)
                     /gene="hk02"
                     /locus_tag="spr1106"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensory box sensor histidine kinase"
                     /protein_id="NP_358699.1"
                     /db_xref="GI:15903149"
                     /db_xref="GeneID:933765"
     gene            complement(1107604..1108359)
                     /gene="rr02"
                     /locus_tag="spr1107"
                     /db_xref="GeneID:932912"
     CDS             complement(1107604..1108359)
                     /gene="rr02"
                     /locus_tag="spr1107"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_358700.1"
                     /db_xref="GI:15903150"
                     /db_xref="GeneID:932912"
     gene            complement(1108363..1109538)
                     /gene="mutY"
                     /locus_tag="spr1108"
                     /db_xref="GeneID:933900"
     CDS             complement(1108363..1109538)
                     /gene="mutY"
                     /locus_tag="spr1108"
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="NP_358701.1"
                     /db_xref="GI:15903151"
                     /db_xref="GeneID:933900"
     repeat_region   complement(1109625..1109779)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1109867..1111537)
                     /gene="fhs"
                     /locus_tag="spr1109"
                     /db_xref="GeneID:933045"
     CDS             complement(1109867..1111537)
                     /gene="fhs"
                     /locus_tag="spr1109"
                     /EC_number="6.3.4.3"
                     /note="catalyzes the formation of
                     10-formyltetrahydrofolate from formate and
                     tetrahydrofolate"
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="NP_358702.1"
                     /db_xref="GI:15903152"
                     /db_xref="GeneID:933045"
     gene            1111752..1112456
                     /gene="dfp-C-terminus"
                     /locus_tag="spr1110"
                     /db_xref="GeneID:933205"
     CDS             1111752..1112456
                     /gene="dfp-C-terminus"
                     /locus_tag="spr1110"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="NP_358703.1"
                     /db_xref="GI:15903153"
                     /db_xref="GeneID:933205"
     gene            1112468..1113019
                     /gene="dfp-N-terminus"
                     /locus_tag="spr1111"
                     /db_xref="GeneID:933762"
     CDS             1112468..1113019
                     /gene="dfp-N-terminus"
                     /locus_tag="spr1111"
                     /EC_number="4.1.1.36"
                     /note="decarboxylates 4-phosphopantothenoylcysteine to
                     form 4'-phosphopantotheine."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="NP_358704.1"
                     /db_xref="GI:15903154"
                     /db_xref="GeneID:933762"
     gene            1113003..1113566
                     /locus_tag="spr1112"
                     /db_xref="GeneID:932957"
     CDS             1113003..1113566
                     /locus_tag="spr1112"
                     /note="Probable membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358705.1"
                     /db_xref="GI:15903155"
                     /db_xref="GeneID:932957"
     repeat_region   complement(1113638..1113744)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            1113794..1114375
                     /locus_tag="spr1113"
                     /db_xref="GeneID:933218"
     CDS             1113794..1114375
                     /locus_tag="spr1113"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358706.1"
                     /db_xref="GI:15903156"
                     /db_xref="GeneID:933218"
     gene            1114387..1114902
                     /locus_tag="spr1114"
                     /db_xref="GeneID:932954"
     CDS             1114387..1114902
                     /locus_tag="spr1114"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358707.1"
                     /db_xref="GI:15903157"
                     /db_xref="GeneID:932954"
     gene            complement(1114899..1115366)
                     /locus_tag="spr1115"
                     /db_xref="GeneID:932945"
     CDS             complement(1114899..1115366)
                     /locus_tag="spr1115"
                     /note="MutT-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358708.1"
                     /db_xref="GI:15903158"
                     /db_xref="GeneID:932945"
     gene            complement(1115440..1115928)
                     /locus_tag="spr1116"
                     /db_xref="GeneID:933162"
     CDS             complement(1115440..1115928)
                     /locus_tag="spr1116"
                     /note="Acetyltransferase (GNAT) family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358709.1"
                     /db_xref="GI:15903159"
                     /db_xref="GeneID:933162"
     gene            complement(1115894..1116457)
                     /locus_tag="spr1117"
                     /db_xref="GeneID:933313"
     CDS             complement(1115894..1116457)
                     /locus_tag="spr1117"
                     /note="Probable acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358710.1"
                     /db_xref="GI:15903160"
                     /db_xref="GeneID:933313"
     gene            complement(1116467..1118455)
                     /gene="uvrB"
                     /locus_tag="spr1118"
                     /db_xref="GeneID:933244"
     CDS             complement(1116467..1118455)
                     /gene="uvrB"
                     /locus_tag="spr1118"
                     /note="The UvrABC repair system catalyzes the recognition
                     and processing of DNA lesions. The beta-hairpin of the
                     Uvr-B subunit is inserted between the strands, where it
                     probes for the presence of a lesion"
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="NP_358711.1"
                     /db_xref="GI:15903161"
                     /db_xref="GeneID:933244"
     gene            complement(1118532..1119485)
                     /locus_tag="spr1119"
                     /db_xref="GeneID:933140"
     CDS             complement(1118532..1119485)
                     /locus_tag="spr1119"
                     /note="transmembrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358712.1"
                     /db_xref="GI:15903162"
                     /db_xref="GeneID:933140"
     gene            1119658..1121823
                     /gene="glnP"
                     /locus_tag="spr1120"
                     /db_xref="GeneID:934028"
     CDS             1119658..1121823
                     /gene="glnP"
                     /locus_tag="spr1120"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358713.1"
                     /db_xref="GI:15903163"
                     /db_xref="GeneID:934028"
     gene            1121823..1122563
                     /gene="glnQ"
                     /locus_tag="spr1121"
                     /db_xref="GeneID:933796"
     CDS             1121823..1122563
                     /gene="glnQ"
                     /locus_tag="spr1121"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358714.1"
                     /db_xref="GI:15903164"
                     /db_xref="GeneID:933796"
     gene            1122712..1124199
                     /gene="zwf"
                     /locus_tag="spr1122"
                     /db_xref="GeneID:933288"
     CDS             1122712..1124199
                     /gene="zwf"
                     /locus_tag="spr1122"
                     /EC_number="1.1.1.49"
                     /note="catalyzes the formation of D-glucono-1,5-lactone
                     6-phosphate from D-glucose 6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase"
                     /protein_id="NP_358715.1"
                     /db_xref="GI:15903165"
                     /db_xref="GeneID:933288"
     gene            complement(1124245..1125522)
                     /gene="ftsY"
                     /locus_tag="spr1123"
                     /db_xref="GeneID:933257"
     CDS             complement(1124245..1125522)
                     /gene="ftsY"
                     /locus_tag="spr1123"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="NP_358716.1"
                     /db_xref="GI:15903166"
                     /db_xref="GeneID:933257"
     gene            complement(1125526..1126344)
                     /locus_tag="spr1124"
                     /db_xref="GeneID:933814"
     CDS             complement(1125526..1126344)
                     /locus_tag="spr1124"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_358717.1"
                     /db_xref="GI:15903167"
                     /db_xref="GeneID:933814"
     gene            complement(1126344..1127138)
                     /locus_tag="spr1125"
                     /db_xref="GeneID:933655"
     CDS             complement(1126344..1127138)
                     /locus_tag="spr1125"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_358718.1"
                     /db_xref="GI:15903168"
                     /db_xref="GeneID:933655"
     gene            complement(1127135..1130674)
                     /gene="smc"
                     /locus_tag="spr1126"
                     /db_xref="GeneID:933157"
     CDS             complement(1127135..1130674)
                     /gene="smc"
                     /locus_tag="spr1126"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome condensation and segregation SMC
                     protein"
                     /protein_id="NP_358719.1"
                     /db_xref="GI:15903169"
                     /db_xref="GeneID:933157"
     gene            complement(1130665..1131363)
                     /gene="rnc"
                     /locus_tag="spr1127"
                     /db_xref="GeneID:932926"
     CDS             complement(1130665..1131363)
                     /gene="rnc"
                     /locus_tag="spr1127"
                     /EC_number="3.1.26.3"
                     /note="cytoplasmic enzyme involved in processing rRNA and
                     some mRNAs; substrates typically have dsRNA regions; forms
                     a homodimer; have N-terminal nuclease and C-terminal
                     RNA-binding domains; requires magnesium as preferred ion
                     for activity"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="NP_358720.1"
                     /db_xref="GI:15903170"
                     /db_xref="GeneID:932926"
     gene            complement(1131546..1131617)
                     /gene="tRNA-Arg1"
                     /locus_tag="sprt08"
                     /db_xref="GeneID:932814"
     tRNA            complement(1131546..1131617)
                     /gene="tRNA-Arg1"
                     /locus_tag="sprt08"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:932814"
     gene            complement(1131681..1132667)
                     /gene="guaC"
                     /locus_tag="spr1128"
                     /db_xref="GeneID:933293"
     CDS             complement(1131681..1132667)
                     /gene="guaC"
                     /locus_tag="spr1128"
                     /EC_number="1.7.1.7"
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine 5'-monophosphate oxidoreductase"
                     /protein_id="NP_358721.1"
                     /db_xref="GI:15903171"
                     /db_xref="GeneID:933293"
     gene            complement(1132842..1134185)
                     /locus_tag="spr1129"
                     /db_xref="GeneID:932798"
     CDS             complement(1132842..1134185)
                     /locus_tag="spr1129"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358722.1"
                     /db_xref="GI:15903172"
                     /db_xref="GeneID:932798"
     gene            complement(1134145..1136079)
                     /locus_tag="spr1130"
                     /db_xref="GeneID:933897"
     CDS             complement(1134145..1136079)
                     /locus_tag="spr1130"
                     /note="Probable endonuclease"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease"
                     /protein_id="NP_358723.1"
                     /db_xref="GI:15903173"
                     /db_xref="GeneID:933897"
     gene            complement(1136240..1136410)
                     /locus_tag="spr1131"
                     /db_xref="GeneID:933326"
     CDS             complement(1136240..1136410)
                     /locus_tag="spr1131"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358724.1"
                     /db_xref="GI:15903174"
                     /db_xref="GeneID:933326"
     gene            complement(1136391..1136564)
                     /locus_tag="spr1132"
                     /db_xref="GeneID:932830"
     CDS             complement(1136391..1136564)
                     /locus_tag="spr1132"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358725.1"
                     /db_xref="GI:15903175"
                     /db_xref="GeneID:932830"
     gene            complement(1137389..1137658)
                     /locus_tag="spr1134"
                     /db_xref="GeneID:932826"
     CDS             complement(1137389..1137658)
                     /locus_tag="spr1134"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358727.1"
                     /db_xref="GI:15903177"
                     /db_xref="GeneID:932826"
     gene            complement(1137655..1138692)
                     /gene="leuB"
                     /locus_tag="spr1135"
                     /db_xref="GeneID:933207"
     CDS             complement(1137655..1138692)
                     /gene="leuB"
                     /locus_tag="spr1135"
                     /EC_number="1.1.1.85"
                     /note="catalyzes the oxidation of 3-isopropylmalate to
                     3-carboxy-4-methyl-2-oxopentanoate in leucine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="NP_358728.1"
                     /db_xref="GI:15903178"
                     /db_xref="GeneID:933207"
     gene            complement(1138704..1139798)
                     /gene="leuA-truncation"
                     /locus_tag="spr1136"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934061"
     gene            complement(1139817..1140473)
                     /locus_tag="spr1138"
                     /db_xref="GeneID:933271"
     CDS             complement(1139817..1140473)
                     /locus_tag="spr1138"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358731.1"
                     /db_xref="GI:15903181"
                     /db_xref="GeneID:933271"
     gene            complement(1140517..1141149)
                     /gene="cutC"
                     /locus_tag="spr1139"
                     /db_xref="GeneID:932966"
     CDS             complement(1140517..1141149)
                     /gene="cutC"
                     /locus_tag="spr1139"
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="NP_358732.1"
                     /db_xref="GI:15903182"
                     /db_xref="GeneID:932966"
     gene            complement(1141242..1141601)
                     /locus_tag="spr1140"
                     /db_xref="GeneID:933904"
     CDS             complement(1141242..1141601)
                     /locus_tag="spr1140"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358733.1"
                     /db_xref="GI:15903183"
                     /db_xref="GeneID:933904"
     gene            complement(1141707..1143812)
                     /gene="topA"
                     /locus_tag="spr1141"
                     /db_xref="GeneID:933880"
     CDS             complement(1141707..1143812)
                     /gene="topA"
                     /locus_tag="spr1141"
                     /EC_number="5.99.1.2"
                     /note="catalyzes the ATP-dependent breakage of
                     single-stranded DNA followed by passage and rejoining,
                     maintains net negative superhelicity"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="NP_358734.1"
                     /db_xref="GI:15903184"
                     /db_xref="GeneID:933880"
     gene            complement(1143961..1145004)
                     /locus_tag="spr1142"
                     /db_xref="GeneID:933253"
     CDS             complement(1143961..1145004)
                     /locus_tag="spr1142"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358735.1"
                     /db_xref="GI:15903185"
                     /db_xref="GeneID:933253"
     repeat_region   complement(1145161..1145255)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     repeat_region   1145464..1145562
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     repeat_region   complement(1145578..1145740)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1145894..1146754)
                     /gene="smf"
                     /locus_tag="spr1144"
                     /db_xref="GeneID:933320"
     CDS             complement(1145894..1146754)
                     /gene="smf"
                     /locus_tag="spr1144"
                     /note="Also known as Competence induced loci B, CilB"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA processing protein DprA"
                     /protein_id="NP_358737.1"
                     /db_xref="GI:15903187"
                     /db_xref="GeneID:933320"
     gene            complement(1146838..1147527)
                     /gene="licC"
                     /locus_tag="spr1145"
                     /db_xref="GeneID:933831"
     CDS             complement(1146838..1147527)
                     /gene="licC"
                     /locus_tag="spr1145"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358738.1"
                     /db_xref="GI:15903188"
                     /db_xref="GeneID:933831"
     gene            complement(1147539..1148429)
                     /gene="licB"
                     /locus_tag="spr1146"
                     /db_xref="GeneID:933852"
     CDS             complement(1147539..1148429)
                     /gene="licB"
                     /locus_tag="spr1146"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358739.1"
                     /db_xref="GI:15903189"
                     /db_xref="GeneID:933852"
     gene            complement(1148407..1149276)
                     /gene="pck"
                     /locus_tag="spr1147"
                     /db_xref="GeneID:933258"
     CDS             complement(1148407..1149276)
                     /gene="pck"
                     /locus_tag="spr1147"
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase"
                     /protein_id="NP_358740.1"
                     /db_xref="GI:15903190"
                     /db_xref="GeneID:933258"
     gene            complement(1149293..1150333)
                     /locus_tag="spr1148"
                     /db_xref="GeneID:932935"
     CDS             complement(1149293..1150333)
                     /locus_tag="spr1148"
                     /note="Probable oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-containing alcohol dehydrogenase"
                     /protein_id="NP_358741.1"
                     /db_xref="GI:15903191"
                     /db_xref="GeneID:932935"
     gene            complement(1150320..1151027)
                     /gene="ispD"
                     /locus_tag="spr1149"
                     /db_xref="GeneID:933316"
     CDS             complement(1150320..1151027)
                     /gene="ispD"
                     /locus_tag="spr1149"
                     /EC_number="2.7.7.60"
                     /note="4-diphosphocytidyl-2C-methyl-D-erythritol synthase;
                     MEP cytidylyltransferase; MCT; catalyzes the formation of
                     4-diphosphocytidyl-2-C-methyl-D-erythritol from CTP and
                     2-C-methyl-D-erythritol 4-phosphate; involved in
                     isoprenoid and isopentenyl-PP biosynthesis; forms
                     homodimers"
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="NP_358742.1"
                     /db_xref="GI:15903192"
                     /db_xref="GeneID:933316"
     gene            1151363..1152850
                     /locus_tag="spr1150"
                     /db_xref="GeneID:933321"
     CDS             1151363..1152850
                     /locus_tag="spr1150"
                     /note="Probable oligosaccharide repeat unit transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="NP_358743.1"
                     /db_xref="GI:15903193"
                     /db_xref="GeneID:933321"
     gene            1152860..1153663
                     /gene="licD1"
                     /locus_tag="spr1151"
                     /db_xref="GeneID:933252"
     CDS             1152860..1153663
                     /gene="licD1"
                     /locus_tag="spr1151"
                     /codon_start=1
                     /transl_table=11
                     /product="required for phosphorylcholine incorporation in
                     teichoic and lipoteichoic acids"
                     /protein_id="NP_358744.1"
                     /db_xref="GI:15903194"
                     /db_xref="GeneID:933252"
     gene            1153665..1154474
                     /gene="licD2"
                     /locus_tag="spr1152"
                     /db_xref="GeneID:933341"
     CDS             1153665..1154474
                     /gene="licD2"
                     /locus_tag="spr1152"
                     /note="Required for phosphorylcholine incorporation in
                     teichoic and lipoteichoic acids"
                     /codon_start=1
                     /transl_table=11
                     /product="licD protein"
                     /protein_id="NP_358745.1"
                     /db_xref="GI:15903195"
                     /db_xref="GeneID:933341"
     repeat_region   complement(1154628..1154697)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            complement(1154749..1157925)
                     /gene="carB"
                     /locus_tag="spr1153"
                     /db_xref="GeneID:933355"
     CDS             complement(1154749..1157925)
                     /gene="carB"
                     /locus_tag="spr1153"
                     /EC_number="6.3.5.5"
                     /note="four CarB-CarA dimers form the carbamoyl phosphate
                     synthetase holoenzyme that catalyzes the production of
                     carbamoyl phosphate; CarB is responsible for the
                     amidotransferase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase large subunit"
                     /protein_id="NP_358746.1"
                     /db_xref="GI:15903196"
                     /db_xref="GeneID:933355"
     gene            complement(1158238..1159317)
                     /gene="carA"
                     /locus_tag="spr1154"
                     /db_xref="GeneID:933238"
     CDS             complement(1158238..1159317)
                     /gene="carA"
                     /locus_tag="spr1154"
                     /EC_number="6.3.5.5"
                     /note="catalyzes production of carbamoyl phosphate from
                     bicarbonate and glutamine in pyrimidine and arginine
                     biosynthesis pathways; forms an octamer composed of four
                     CarAB dimers"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl phosphate synthase small subunit"
                     /protein_id="NP_358747.1"
                     /db_xref="GI:15903197"
                     /db_xref="GeneID:933238"
     gene            complement(1159367..1160290)
                     /gene="pyrB"
                     /locus_tag="spr1155"
                     /db_xref="GeneID:933189"
     CDS             complement(1159367..1160290)
                     /gene="pyrB"
                     /locus_tag="spr1155"
                     /EC_number="2.1.3.2"
                     /note="catalyzes the transfer of the carbamoyl moiety from
                     carbamoyl phosphate to L- aspartate in pyrimidine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="NP_358748.1"
                     /db_xref="GI:15903198"
                     /db_xref="GeneID:933189"
     gene            complement(1160309..1160830)
                     /gene="pyrR"
                     /locus_tag="spr1156"
                     /db_xref="GeneID:933441"
     CDS             complement(1160309..1160830)
                     /gene="pyrR"
                     /locus_tag="spr1156"
                     /EC_number="2.4.2.9"
                     /note="regulates pyrimidine biosynthesis by binding to the
                     mRNA of the pyr genes, also has been shown to have uracil
                     phosphoribosyltransferase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyrimidine regulatory protein PyrR
                     uracil phosphoribosyltransferase"
                     /protein_id="NP_358749.1"
                     /db_xref="GI:15903199"
                     /db_xref="GeneID:933441"
     gene            complement(1161041..1161670)
                     /gene="nth"
                     /locus_tag="spr1157"
                     /db_xref="GeneID:933279"
     CDS             complement(1161041..1161670)
                     /gene="nth"
                     /locus_tag="spr1157"
                     /EC_number="4.2.99.18"
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="NP_358750.1"
                     /db_xref="GI:15903200"
                     /db_xref="GeneID:933279"
     gene            complement(1161670..1162212)
                     /locus_tag="spr1158"
                     /db_xref="GeneID:933191"
     CDS             complement(1161670..1162212)
                     /locus_tag="spr1158"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358751.1"
                     /db_xref="GI:15903201"
                     /db_xref="GeneID:933191"
     gene            1162382..1162698
                     /locus_tag="spr1159"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934031"
     gene            1162971..1164497
                     /gene="ABC-NBD"
                     /locus_tag="spr1161"
                     /db_xref="GeneID:933416"
     CDS             1162971..1164497
                     /gene="ABC-NBD"
                     /locus_tag="spr1161"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358754.1"
                     /db_xref="GI:15903204"
                     /db_xref="GeneID:933416"
     gene            complement(1164646..1165554)
                     /gene="htpX"
                     /locus_tag="spr1162"
                     /db_xref="GeneID:932914"
     CDS             complement(1164646..1165554)
                     /gene="htpX"
                     /locus_tag="spr1162"
                     /note="metalloprotease"
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HtpX"
                     /protein_id="NP_358755.1"
                     /db_xref="GI:15903205"
                     /db_xref="GeneID:932914"
     gene            complement(1165547..1166107)
                     /gene="lemA"
                     /locus_tag="spr1163"
                     /db_xref="GeneID:934068"
     CDS             complement(1165547..1166107)
                     /gene="lemA"
                     /locus_tag="spr1163"
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic membrane protein"
                     /protein_id="NP_358756.1"
                     /db_xref="GI:15903206"
                     /db_xref="GeneID:934068"
     gene            1166177..1166914
                     /gene="gidB"
                     /locus_tag="spr1164"
                     /db_xref="GeneID:933340"
     CDS             1166177..1166914
                     /gene="gidB"
                     /locus_tag="spr1164"
                     /note="glucose-inhibited division protein B; SAM-dependent
                     methyltransferase; methylates the N7 position of guanosine
                     in position 527 of 16S rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA methyltransferase GidB"
                     /protein_id="NP_358757.1"
                     /db_xref="GI:15903207"
                     /db_xref="GeneID:933340"
     gene            1167230..1168549
                     /gene="pyrP"
                     /locus_tag="spr1165"
                     /db_xref="GeneID:933249"
     CDS             1167230..1168549
                     /gene="pyrP"
                     /locus_tag="spr1165"
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="NP_358758.1"
                     /db_xref="GI:15903208"
                     /db_xref="GeneID:933249"
     gene            complement(1168744..1170315)
                     /gene="ffh"
                     /locus_tag="spr1166"
                     /db_xref="GeneID:933912"
     CDS             complement(1168744..1170315)
                     /gene="ffh"
                     /locus_tag="spr1166"
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="NP_358759.1"
                     /db_xref="GI:15903209"
                     /db_xref="GeneID:933912"
     gene            complement(1170327..1170659)
                     /locus_tag="spr1167"
                     /db_xref="GeneID:932921"
     CDS             complement(1170327..1170659)
                     /locus_tag="spr1167"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="NP_358760.1"
                     /db_xref="GI:15903210"
                     /db_xref="GeneID:932921"
     gene            complement(1170750..1171127)
                     /locus_tag="spr1168"
                     /db_xref="GeneID:933175"
     CDS             complement(1170750..1171127)
                     /locus_tag="spr1168"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358761.1"
                     /db_xref="GI:15903211"
                     /db_xref="GeneID:933175"
     gene            1171103..1172503
                     /locus_tag="spr1169"
                     /db_xref="GeneID:933220"
     CDS             1171103..1172503
                     /locus_tag="spr1169"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358762.1"
                     /db_xref="GI:15903212"
                     /db_xref="GeneID:933220"
     gene            1172516..1173322
                     /locus_tag="spr1170"
                     /db_xref="GeneID:933184"
     CDS             1172516..1173322
                     /locus_tag="spr1170"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_358763.1"
                     /db_xref="GI:15903213"
                     /db_xref="GeneID:933184"
     gene            complement(1173377..1173448)
                     /gene="tRNA-Arg2"
                     /locus_tag="sprt09"
                     /db_xref="GeneID:933501"
     tRNA            complement(1173377..1173448)
                     /gene="tRNA-Arg2"
                     /locus_tag="sprt09"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:933501"
     gene            complement(1173490..1173837)
                     /gene="rplS"
                     /locus_tag="spr1171"
                     /db_xref="GeneID:932995"
     CDS             complement(1173490..1173837)
                     /gene="rplS"
                     /locus_tag="spr1171"
                     /note="this protein is located at the 30S-50S ribosomal
                     subunit interface and may play a role in the structure and
                     function of the aminoacyl-tRNA binding site"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="NP_358764.1"
                     /db_xref="GI:15903214"
                     /db_xref="GeneID:932995"
     gene            complement(1173956..1174285)
                     /gene="crcB"
                     /locus_tag="spr1172"
                     /db_xref="GeneID:933959"
     CDS             complement(1173956..1174285)
                     /gene="crcB"
                     /locus_tag="spr1172"
                     /note="may be involved in chromosome condensation;
                     overexpression in Escherichia coli protects against
                     decondensation by camphor; overexpressing the protein
                     results in an increase in supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="camphor resistance protein CrcB"
                     /protein_id="NP_358765.1"
                     /db_xref="GI:15903215"
                     /db_xref="GeneID:933959"
     gene            complement(1174279..1174653)
                     /gene="crcB"
                     /locus_tag="spr1173"
                     /db_xref="GeneID:934163"
     CDS             complement(1174279..1174653)
                     /gene="crcB"
                     /locus_tag="spr1173"
                     /note="may be involved in chromosome condensation;
                     overexpression in Escherichia coli protects against
                     decondensation by camphor; overexpressing the protein
                     results in an increase in supercoiling"
                     /codon_start=1
                     /transl_table=11
                     /product="camphor resistance protein CrcB"
                     /protein_id="NP_358766.1"
                     /db_xref="GI:15903216"
                     /db_xref="GeneID:934163"
     gene            complement(1174650..1174916)
                     /locus_tag="spr1174"
                     /db_xref="GeneID:933949"
     CDS             complement(1174650..1174916)
                     /locus_tag="spr1174"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358767.1"
                     /db_xref="GI:15903217"
                     /db_xref="GeneID:933949"
     gene            complement(1175032..1175475)
                     /gene="flaV"
                     /locus_tag="spr1175"
                     /db_xref="GeneID:933952"
     CDS             complement(1175032..1175475)
                     /gene="flaV"
                     /locus_tag="spr1175"
                     /note="An electron-transfer protein; flavodoxin binds one
                     FMN molecule, which serves as a redox-active prosthetic
                     group"
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="NP_358768.1"
                     /db_xref="GI:15903218"
                     /db_xref="GeneID:933952"
     gene            1175567..1176514
                     /locus_tag="spr1176"
                     /db_xref="GeneID:933806"
     CDS             1175567..1176514
                     /locus_tag="spr1176"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH subfamily 1 protein"
                     /protein_id="NP_358769.1"
                     /db_xref="GI:15903219"
                     /db_xref="GeneID:933806"
     STS             1175648..1176308
                     /locus_tag="spr1176"
                     /standard_name="D10Bir8"
                     /db_xref="UniSTS:141487"
     gene            1176610..1176852
                     /gene="rpmE2"
                     /locus_tag="spr1177"
                     /db_xref="GeneID:933825"
     CDS             1176610..1176852
                     /gene="rpmE2"
                     /locus_tag="spr1177"
                     /note="RpmE2; there appears to be two types of ribosomal
                     proteins L31 in bacterial genomes; some contain a CxxC
                     motif while others do not; Bacillus subtilis has both
                     types; the proteins in this cluster do not have the CXXC
                     motif; RpmE is found in exponentially growing Bacilli
                     while YtiA was found after exponential growth; expression
                     of ytiA is controlled by a zinc-specific transcriptional
                     repressor; RpmE contains one zinc ion and a CxxC motif is
                     responsible for this binding; forms an RNP particle along
                     with proteins L5, L18, and L25 and 5S rRNA; found
                     crosslinked to L2 and L25 and EF-G; may be near the
                     peptidyltransferase site of the 50S ribosome"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="NP_358770.1"
                     /db_xref="GI:15903220"
                     /db_xref="GeneID:933825"
     gene            complement(1176909..1177487)
                     /locus_tag="spr1178"
                     /db_xref="GeneID:933834"
     CDS             complement(1176909..1177487)
                     /locus_tag="spr1178"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358771.1"
                     /db_xref="GI:15903221"
                     /db_xref="GeneID:933834"
     gene            complement(1177462..1178466)
                     /locus_tag="spr1179"
                     /db_xref="GeneID:933059"
     CDS             complement(1177462..1178466)
                     /locus_tag="spr1179"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358772.1"
                     /db_xref="GI:15903222"
                     /db_xref="GeneID:933059"
     gene            complement(1178518..1178922)
                     /gene="transposase_C"
                     /locus_tag="spr1180"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934141"
     repeat_region   1178931..1179037
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            1179472..1180818
                     /gene="gdhA"
                     /locus_tag="spr1181"
                     /db_xref="GeneID:934142"
     CDS             1179472..1180818
                     /gene="gdhA"
                     /locus_tag="spr1181"
                     /EC_number="1.4.1.4"
                     /note="converts 2-oxoglutarate to glutamate; in
                     Escherichia coli this enzyme plays a role in glutamate
                     synthesis when the cell is under energy restriction; uses
                     NADPH; forms a homohexamer"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate dehydrogenase"
                     /protein_id="NP_358774.1"
                     /db_xref="GI:15903224"
                     /db_xref="GeneID:934142"
     repeat_region   1180934..1181001
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     repeat_region   complement(1181025..1181132)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1181314..1181484)
                     /locus_tag="spr1182"
                     /db_xref="GeneID:934144"
     CDS             complement(1181314..1181484)
                     /locus_tag="spr1182"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358775.1"
                     /db_xref="GI:15903225"
                     /db_xref="GeneID:934144"
     gene            complement(1181497..1182138)
                     /locus_tag="spr1183"
                     /db_xref="GeneID:934145"
     CDS             complement(1181497..1182138)
                     /locus_tag="spr1183"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358776.1"
                     /db_xref="GI:15903226"
                     /db_xref="GeneID:934145"
     gene            1182410..1182917
                     /locus_tag="spr1184"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934146"
     gene            complement(1183138..1183341)
                     /locus_tag="spr1185"
                     /db_xref="GeneID:934148"
     CDS             complement(1183138..1183341)
                     /locus_tag="spr1185"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358778.1"
                     /db_xref="GI:15903228"
                     /db_xref="GeneID:934148"
     gene            complement(1184308..1184715)
                     /gene="cdd"
                     /locus_tag="spr1188"
                     /db_xref="GeneID:934151"
     CDS             complement(1184308..1184715)
                     /gene="cdd"
                     /locus_tag="spr1188"
                     /EC_number="3.5.4.5"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="NP_358781.1"
                     /db_xref="GI:15903231"
                     /db_xref="GeneID:934151"
     repeat_region   complement(1184756..1184862)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1185003..1185491)
                     /locus_tag="spr1189"
                     /db_xref="GeneID:934152"
     CDS             complement(1185003..1185491)
                     /locus_tag="spr1189"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358782.1"
                     /db_xref="GI:15903232"
                     /db_xref="GeneID:934152"
     gene            complement(1185496..1186914)
                     /locus_tag="spr1190"
                     /db_xref="GeneID:934153"
     CDS             complement(1185496..1186914)
                     /locus_tag="spr1190"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358783.1"
                     /db_xref="GI:15903233"
                     /db_xref="GeneID:934153"
     gene            complement(1186915..1188897)
                     /gene="appD"
                     /locus_tag="spr1191"
                     /db_xref="GeneID:934155"
     CDS             complement(1186915..1188897)
                     /gene="appD"
                     /locus_tag="spr1191"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein"
                     /protein_id="NP_358784.1"
                     /db_xref="GI:15903234"
                     /db_xref="GeneID:934155"
     gene            complement(1188910..1189761)
                     /gene="appC"
                     /locus_tag="spr1192"
                     /db_xref="GeneID:934156"
     CDS             complement(1188910..1189761)
                     /gene="appC"
                     /locus_tag="spr1192"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="NP_358785.1"
                     /db_xref="GI:15903235"
                     /db_xref="GeneID:934156"
     gene            complement(1189778..1190773)
                     /gene="appB"
                     /locus_tag="spr1193"
                     /db_xref="GeneID:934157"
     CDS             complement(1189778..1190773)
                     /gene="appB"
                     /locus_tag="spr1193"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease"
                     /protein_id="NP_358786.1"
                     /db_xref="GI:15903236"
                     /db_xref="GeneID:934157"
     gene            complement(1190838..1192466)
                     /gene="appA"
                     /locus_tag="spr1194"
                     /db_xref="GeneID:934158"
     CDS             complement(1190838..1192466)
                     /gene="appA"
                     /locus_tag="spr1194"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358787.1"
                     /db_xref="GI:15903237"
                     /db_xref="GeneID:934158"
     gene            complement(1192548..1193471)
                     /locus_tag="spr1195"
                     /db_xref="GeneID:932793"
     CDS             complement(1192548..1193471)
                     /locus_tag="spr1195"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358788.1"
                     /db_xref="GI:15903238"
                     /db_xref="GeneID:932793"
     gene            complement(1193495..1194193)
                     /gene="nanE"
                     /locus_tag="spr1196"
                     /db_xref="GeneID:934409"
     CDS             complement(1193495..1194193)
                     /gene="nanE"
                     /locus_tag="spr1196"
                     /EC_number="5.1.3.9"
                     /note="Converts N-acetylmannosamine-6-phosphate to
                     N-acetylglucosamine-6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="NP_358789.1"
                     /db_xref="GI:15903239"
                     /db_xref="GeneID:934409"
     gene            complement(1195086..1195307)
                     /locus_tag="spr1199"
                     /db_xref="GeneID:934412"
     CDS             complement(1195086..1195307)
                     /locus_tag="spr1199"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358792.1"
                     /db_xref="GI:15903242"
                     /db_xref="GeneID:934412"
     gene            complement(1196371..1197690)
                     /locus_tag="spr1201"
                     /db_xref="GeneID:934413"
     CDS             complement(1196371..1197690)
                     /locus_tag="spr1201"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358794.1"
                     /db_xref="GI:15903244"
                     /db_xref="GeneID:934413"
     gene            complement(1197693..1198451)
                     /gene="ABC-NDB"
                     /locus_tag="spr1202"
                     /db_xref="GeneID:934415"
     CDS             complement(1197693..1198451)
                     /gene="ABC-NDB"
                     /locus_tag="spr1202"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358795.1"
                     /db_xref="GI:15903245"
                     /db_xref="GeneID:934415"
     gene            complement(1198448..1200055)
                     /gene="ABC-NP"
                     /locus_tag="spr1203"
                     /db_xref="GeneID:934427"
     CDS             complement(1198448..1200055)
                     /gene="ABC-NP"
                     /locus_tag="spr1203"
                     /codon_start=1
                     /transl_table=11
                     /product="drug efflux ABC transporter
                     ATP-binding/permease"
                     /protein_id="NP_358796.1"
                     /db_xref="GI:15903246"
                     /db_xref="GeneID:934427"
     gene            complement(1200052..1201992)
                     /gene="ptrB"
                     /locus_tag="spr1204"
                     /db_xref="GeneID:934419"
     CDS             complement(1200052..1201992)
                     /gene="ptrB"
                     /locus_tag="spr1204"
                     /EC_number="3.4.21.83"
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase"
                     /protein_id="NP_358797.1"
                     /db_xref="GI:15903247"
                     /db_xref="GeneID:934419"
     gene            complement(1202025..1204661)
                     /locus_tag="spr1205"
                     /db_xref="GeneID:934416"
     CDS             complement(1202025..1204661)
                     /locus_tag="spr1205"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358798.1"
                     /db_xref="GI:15903248"
                     /db_xref="GeneID:934416"
     gene            complement(1205152..1205739)
                     /locus_tag="spr1206"
                     /db_xref="GeneID:934423"
     CDS             complement(1205152..1205739)
                     /locus_tag="spr1206"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358799.1"
                     /db_xref="GI:15903249"
                     /db_xref="GeneID:934423"
     gene            complement(1205988..1206368)
                     /locus_tag="spr1207"
                     /db_xref="GeneID:934417"
     CDS             complement(1205988..1206368)
                     /locus_tag="spr1207"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358800.1"
                     /db_xref="GI:15903250"
                     /db_xref="GeneID:934417"
     gene            complement(1206423..1206701)
                     /locus_tag="spr1208"
                     /db_xref="GeneID:934418"
     CDS             complement(1206423..1206701)
                     /locus_tag="spr1208"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358801.1"
                     /db_xref="GI:15903251"
                     /db_xref="GeneID:934418"
     gene            complement(1206709..1206963)
                     /locus_tag="spr1209"
                     /db_xref="GeneID:934425"
     CDS             complement(1206709..1206963)
                     /locus_tag="spr1209"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358802.1"
                     /db_xref="GI:15903252"
                     /db_xref="GeneID:934425"
     gene            complement(1206960..1207172)
                     /locus_tag="spr1210"
                     /db_xref="GeneID:934420"
     CDS             complement(1206960..1207172)
                     /locus_tag="spr1210"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358803.1"
                     /db_xref="GI:15903253"
                     /db_xref="GeneID:934420"
     gene            complement(1207321..1207689)
                     /gene="rplL"
                     /locus_tag="spr1211"
                     /db_xref="GeneID:934421"
     CDS             complement(1207321..1207689)
                     /gene="rplL"
                     /locus_tag="spr1211"
                     /note="present in two forms; L12 is normal, while L7 is
                     aminoacylated at the N-terminal serine; the only multicopy
                     ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two
                     L12 dimers bind L10; critically important for translation
                     efficiency and fidelity; stimulates GTPase activity of
                     translation factors"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="NP_358804.2"
                     /db_xref="GI:161410745"
                     /db_xref="GeneID:934421"
     gene            complement(1207765..1208265)
                     /gene="rplJ"
                     /locus_tag="spr1212"
                     /db_xref="GeneID:934429"
     CDS             complement(1207765..1208265)
                     /gene="rplJ"
                     /locus_tag="spr1212"
                     /note="binds the two ribosomal protein L7/L12 dimers and
                     anchors them to the large ribosomal subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="NP_358805.1"
                     /db_xref="GI:15903255"
                     /db_xref="GeneID:934429"
     gene            complement(1208515..1209831)
                     /gene="trzA"
                     /locus_tag="spr1214"
                     /db_xref="GeneID:934426"
     CDS             complement(1208515..1209831)
                     /gene="trzA"
                     /locus_tag="spr1214"
                     /codon_start=1
                     /transl_table=11
                     /product="chlorohydrolase"
                     /protein_id="NP_358807.2"
                     /db_xref="GI:161410744"
                     /db_xref="GeneID:934426"
     repeat_region   1209806..1209987
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1210076..1211866)
                     /gene="ABC-N/P"
                     /locus_tag="spr1215"
                     /db_xref="GeneID:934428"
     CDS             complement(1210076..1211866)
                     /gene="ABC-N/P"
                     /locus_tag="spr1215"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_358808.1"
                     /db_xref="GI:15903258"
                     /db_xref="GeneID:934428"
     gene            complement(1211829..1213553)
                     /gene="ABC-N/P"
                     /locus_tag="spr1216"
                     /db_xref="GeneID:934430"
     CDS             complement(1211829..1213553)
                     /gene="ABC-N/P"
                     /locus_tag="spr1216"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_358809.1"
                     /db_xref="GI:15903259"
                     /db_xref="GeneID:934430"
     gene            complement(1213611..1214549)
                     /gene="msrA"
                     /locus_tag="spr1217"
                     /db_xref="GeneID:934434"
     CDS             complement(1213611..1214549)
                     /gene="msrA"
                     /locus_tag="spr1217"
                     /note="this fusion consists of methionine sulfoxide A
                     reductase at the N-terminus and B at the C-terminus; A and
                     B are stereospecific enzymes that recognize the damaged
                     produces of oxidative stress, S and R epimers of
                     methionine sulfoxide, respectively; a fusion"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methionine sulfoxide reductase A/B
                     protein"
                     /protein_id="NP_358810.1"
                     /db_xref="GI:15903260"
                     /db_xref="GeneID:934434"
     repeat_region   1214578..1214777
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbbc"
     gene            complement(1214845..1215714)
                     /gene="thrB"
                     /locus_tag="spr1218"
                     /db_xref="GeneID:934431"
     CDS             complement(1214845..1215714)
                     /gene="thrB"
                     /locus_tag="spr1218"
                     /EC_number="2.7.1.39"
                     /note="catalyzes the formation of O-phospho-L-homoserine
                     from L-homoserine in threonine biosynthesis from asparate"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="NP_358811.1"
                     /db_xref="GI:15903261"
                     /db_xref="GeneID:934431"
     gene            complement(1215716..1217002)
                     /gene="hom"
                     /locus_tag="spr1219"
                     /db_xref="GeneID:934437"
     CDS             complement(1215716..1217002)
                     /gene="hom"
                     /locus_tag="spr1219"
                     /EC_number="1.1.1.3"
                     /note="catalyzes the formation of L-aspartate
                     4-semialdehyde from L-homoserine"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="NP_358812.2"
                     /db_xref="GI:229000971"
                     /db_xref="GeneID:934437"
     gene            complement(1217153..1217890)
                     /gene="mecA"
                     /locus_tag="spr1220"
                     /db_xref="GeneID:934432"
     CDS             complement(1217153..1217890)
                     /gene="mecA"
                     /locus_tag="spr1220"
                     /note="enables recognition and targeting of proteins for
                     proteolysis, involved in negative regulation of
                     competence"
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein"
                     /protein_id="NP_358813.1"
                     /db_xref="GI:15903263"
                     /db_xref="GeneID:934432"
     gene            complement(1218032..1219066)
                     /locus_tag="spr1221"
                     /db_xref="GeneID:934433"
     CDS             complement(1218032..1219066)
                     /locus_tag="spr1221"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358814.1"
                     /db_xref="GI:15903264"
                     /db_xref="GeneID:934433"
     gene            complement(1219095..1220528)
                     /locus_tag="spr1222"
                     /db_xref="GeneID:934447"
     CDS             complement(1219095..1220528)
                     /locus_tag="spr1222"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358815.1"
                     /db_xref="GI:15903265"
                     /db_xref="GeneID:934447"
     gene            complement(1220544..1221530)
                     /gene="cps23FU"
                     /locus_tag="spr1223"
                     /db_xref="GeneID:934436"
     CDS             complement(1220544..1221530)
                     /gene="cps23FU"
                     /locus_tag="spr1223"
                     /EC_number="2.4.1.166"
                     /codon_start=1
                     /transl_table=11
                     /product="galactosyl transferase"
                     /protein_id="NP_358816.1"
                     /db_xref="GI:15903266"
                     /db_xref="GeneID:934436"
     gene            complement(1221532..1222689)
                     /locus_tag="spr1224"
                     /db_xref="GeneID:934444"
     CDS             complement(1221532..1222689)
                     /locus_tag="spr1224"
                     /note="Similar to capsular polysaccharide biosynthsis
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358817.1"
                     /db_xref="GI:15903267"
                     /db_xref="GeneID:934444"
     gene            complement(1222625..1223470)
                     /gene="licD1"
                     /locus_tag="spr1225"
                     /db_xref="GeneID:934441"
     CDS             complement(1222625..1223470)
                     /gene="licD1"
                     /locus_tag="spr1225"
                     /codon_start=1
                     /transl_table=11
                     /product="licD protein"
                     /protein_id="NP_358818.1"
                     /db_xref="GI:15903268"
                     /db_xref="GeneID:934441"
     repeat_region   1223592..1223743
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(1223749..1225023)
                     /locus_tag="spr1226"
                     /db_xref="GeneID:934438"
     CDS             complement(1223749..1225023)
                     /locus_tag="spr1226"
                     /note="transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358819.1"
                     /db_xref="GI:15903269"
                     /db_xref="GeneID:934438"
     gene            complement(1225020..1225868)
                     /gene="pheA"
                     /locus_tag="spr1227"
                     /db_xref="GeneID:934451"
     CDS             complement(1225020..1225868)
                     /gene="pheA"
                     /locus_tag="spr1227"
                     /EC_number="4.2.1.51"
                     /note="catalyzes the formation of phenylpyruvate from
                     prephenate in phenylalanine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="NP_358820.1"
                     /db_xref="GI:15903270"
                     /db_xref="GeneID:934451"
     gene            complement(1225865..1226341)
                     /gene="aroK"
                     /locus_tag="spr1228"
                     /db_xref="GeneID:934443"
     CDS             complement(1225865..1226341)
                     /gene="aroK"
                     /locus_tag="spr1228"
                     /EC_number="2.7.1.71"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="NP_358821.1"
                     /db_xref="GI:15903271"
                     /db_xref="GeneID:934443"
     gene            complement(1226334..1227629)
                     /gene="aroA"
                     /locus_tag="spr1229"
                     /db_xref="GeneID:934439"
     CDS             complement(1226334..1227629)
                     /gene="aroA"
                     /locus_tag="spr1229"
                     /EC_number="2.5.1.19"
                     /note="catalyzes the formation of
                     5-O-(1-carboxyvinyl)-3-phosphoshikimate from
                     phosphoenolpyruvate and 3-phosphoshikimate in tryptophan
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="NP_358822.1"
                     /db_xref="GI:15903272"
                     /db_xref="GeneID:934439"
     gene            complement(1227709..1228047)
                     /locus_tag="spr1230"
                     /db_xref="GeneID:934450"
     CDS             complement(1227709..1228047)
                     /locus_tag="spr1230"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358823.1"
                     /db_xref="GI:15903273"
                     /db_xref="GeneID:934450"
     gene            complement(1228058..1229161)
                     /gene="tyrA"
                     /locus_tag="spr1231"
                     /db_xref="GeneID:934440"
     CDS             complement(1228058..1229161)
                     /gene="tyrA"
                     /locus_tag="spr1231"
                     /EC_number="1.3.1.12"
                     /note="catalyzes the formation of 4-hydroxyphenylpyruvate
                     from prephenate"
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="NP_358824.1"
                     /db_xref="GI:15903274"
                     /db_xref="GeneID:934440"
     gene            complement(1229171..1230337)
                     /gene="aroC"
                     /locus_tag="spr1232"
                     /db_xref="GeneID:934448"
     CDS             complement(1229171..1230337)
                     /gene="aroC"
                     /locus_tag="spr1232"
                     /EC_number="4.2.3.5"
                     /note="catalyzes the formation of chorismate from
                     5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino
                     acid biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="NP_358825.1"
                     /db_xref="GI:15903275"
                     /db_xref="GeneID:934448"
     gene            complement(1230347..1231414)
                     /gene="aroB"
                     /locus_tag="spr1233"
                     /db_xref="GeneID:934442"
     CDS             complement(1230347..1231414)
                     /gene="aroB"
                     /locus_tag="spr1233"
                     /EC_number="4.2.3.4"
                     /note="catalyzes the formation of 3-dehydroquinate from
                     3-deoxy-arabino-heptulonate 7-phosphate; functions in
                     aromatic amino acid biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="NP_358826.1"
                     /db_xref="GI:15903276"
                     /db_xref="GeneID:934442"
     gene            complement(1231433..1232287)
                     /gene="aroE"
                     /locus_tag="spr1234"
                     /db_xref="GeneID:934445"
     CDS             complement(1231433..1232287)
                     /gene="aroE"
                     /locus_tag="spr1234"
                     /EC_number="1.1.1.25"
                     /note="AroE; catalyzes the conversion of shikimate to
                     3-dehydroshikimate"
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase"
                     /protein_id="NP_358827.1"
                     /db_xref="GI:15903277"
                     /db_xref="GeneID:934445"
     gene            complement(1232277..1232954)
                     /gene="aroD"
                     /locus_tag="spr1235"
                     /db_xref="GeneID:934452"
     CDS             complement(1232277..1232954)
                     /gene="aroD"
                     /locus_tag="spr1235"
                     /EC_number="4.2.1.10"
                     /note="catalyzes the dehydration of 3-dehydroquinate to
                     form 3-dehydroshikimate in aromatic amino acid
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate dehydratase"
                     /protein_id="NP_358828.1"
                     /db_xref="GI:15903278"
                     /db_xref="GeneID:934452"
     gene            complement(1232951..1234123)
                     /locus_tag="spr1236"
                     /db_xref="GeneID:934468"
     CDS             complement(1232951..1234123)
                     /locus_tag="spr1236"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358829.1"
                     /db_xref="GI:15903279"
                     /db_xref="GeneID:934468"
     gene            complement(1234801..1236462)
                     /locus_tag="spr1237"
                     /db_xref="GeneID:934446"
     CDS             complement(1234801..1236462)
                     /locus_tag="spr1237"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358830.1"
                     /db_xref="GI:15903280"
                     /db_xref="GeneID:934446"
     gene            complement(1236416..1237222)
                     /gene="ABC-NBD"
                     /locus_tag="spr1238"
                     /db_xref="GeneID:934455"
     CDS             complement(1236416..1237222)
                     /gene="ABC-NBD"
                     /locus_tag="spr1238"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358831.1"
                     /db_xref="GI:15903281"
                     /db_xref="GeneID:934455"
     gene            1237343..1238797
                     /gene="amy"
                     /locus_tag="spr1239"
                     /db_xref="GeneID:934449"
     CDS             1237343..1238797
                     /gene="amy"
                     /locus_tag="spr1239"
                     /EC_number="3.2.1.1"
                     /note="converts 1,4-alpha-D-glucans to maltodextrin"
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic alpha-amylase"
                     /protein_id="NP_358832.1"
                     /db_xref="GI:15903282"
                     /db_xref="GeneID:934449"
     gene            complement(1238887..1241505)
                     /gene="alaS"
                     /locus_tag="spr1240"
                     /db_xref="GeneID:934453"
     CDS             complement(1238887..1241505)
                     /gene="alaS"
                     /locus_tag="spr1240"
                     /EC_number="6.1.1.7"
                     /note="Catalyzes a two-step reaction, first charging an
                     alanyl molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="alanyl-tRNA synthetase"
                     /protein_id="NP_358833.1"
                     /db_xref="GI:15903283"
                     /db_xref="GeneID:934453"
     gene            complement(1241527..1242024)
                     /locus_tag="spr1241"
                     /db_xref="GeneID:934456"
     CDS             complement(1241527..1242024)
                     /locus_tag="spr1241"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358834.1"
                     /db_xref="GI:15903284"
                     /db_xref="GeneID:934456"
     gene            complement(1242287..1242526)
                     /locus_tag="spr1242"
                     /db_xref="GeneID:934454"
     CDS             complement(1242287..1242526)
                     /locus_tag="spr1242"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358835.1"
                     /db_xref="GI:15903285"
                     /db_xref="GeneID:934454"
     repeat_region   complement(1242552..1242640)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1242787..1243857)
                     /gene="potD"
                     /locus_tag="spr1243"
                     /db_xref="GeneID:934459"
     CDS             complement(1242787..1243857)
                     /gene="potD"
                     /locus_tag="spr1243"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein"
                     /protein_id="NP_358836.1"
                     /db_xref="GI:15903286"
                     /db_xref="GeneID:934459"
     gene            complement(1243854..1244627)
                     /gene="potC"
                     /locus_tag="spr1244"
                     /db_xref="GeneID:934457"
     CDS             complement(1243854..1244627)
                     /gene="potC"
                     /locus_tag="spr1244"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease"
                     /protein_id="NP_358837.1"
                     /db_xref="GI:15903287"
                     /db_xref="GeneID:934457"
     gene            complement(1244624..1245451)
                     /gene="potB"
                     /locus_tag="spr1245"
                     /db_xref="GeneID:934458"
     CDS             complement(1244624..1245451)
                     /gene="potB"
                     /locus_tag="spr1245"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease"
                     /protein_id="NP_358838.1"
                     /db_xref="GI:15903288"
                     /db_xref="GeneID:934458"
     gene            complement(1245411..1246568)
                     /gene="potA"
                     /locus_tag="spr1246"
                     /db_xref="GeneID:934460"
     CDS             complement(1245411..1246568)
                     /gene="potA"
                     /locus_tag="spr1246"
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein"
                     /protein_id="NP_358839.1"
                     /db_xref="GI:15903289"
                     /db_xref="GeneID:934460"
     gene            complement(1246627..1247577)
                     /gene="murB"
                     /locus_tag="spr1247"
                     /db_xref="GeneID:934461"
     CDS             complement(1246627..1247577)
                     /gene="murB"
                     /locus_tag="spr1247"
                     /note="catalyzes the reduction of UDP-N-acetylglucosamine
                     enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylenolpyruvoylglucosamine reductase"
                     /protein_id="NP_358840.1"
                     /db_xref="GI:15903290"
                     /db_xref="GeneID:934461"
     gene            complement(1247689..1248441)
                     /locus_tag="spr1248"
                     /db_xref="GeneID:934464"
     CDS             complement(1247689..1248441)
                     /locus_tag="spr1248"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358841.1"
                     /db_xref="GI:15903291"
                     /db_xref="GeneID:934464"
     gene            complement(1248451..1249182)
                     /gene="aldB"
                     /locus_tag="spr1249"
                     /db_xref="GeneID:934465"
     CDS             complement(1248451..1249182)
                     /gene="aldB"
                     /locus_tag="spr1249"
                     /EC_number="4.1.1.5"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-acetolactate decarboxylase"
                     /protein_id="NP_358842.1"
                     /db_xref="GI:15903292"
                     /db_xref="GeneID:934465"
     gene            1249324..1250595
                     /locus_tag="spr1250"
                     /db_xref="GeneID:934462"
     CDS             1249324..1250595
                     /locus_tag="spr1250"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358843.1"
                     /db_xref="GI:15903293"
                     /db_xref="GeneID:934462"
     gene            complement(1250615..1251430)
                     /gene="glnH"
                     /locus_tag="spr1251"
                     /db_xref="GeneID:934463"
     CDS             complement(1250615..1251430)
                     /gene="glnH"
                     /locus_tag="spr1251"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter amino acid-binding
                     protein"
                     /protein_id="NP_358844.1"
                     /db_xref="GI:15903294"
                     /db_xref="GeneID:934463"
     gene            complement(1251587..1252240)
                     /gene="phoU"
                     /locus_tag="spr1252"
                     /db_xref="GeneID:934483"
     CDS             complement(1251587..1252240)
                     /gene="phoU"
                     /locus_tag="spr1252"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter PhoU"
                     /protein_id="NP_358845.1"
                     /db_xref="GI:15903295"
                     /db_xref="GeneID:934483"
     gene            complement(1252252..1253010)
                     /gene="pstB"
                     /locus_tag="spr1253"
                     /db_xref="GeneID:934467"
     CDS             complement(1252252..1253010)
                     /gene="pstB"
                     /locus_tag="spr1253"
                     /note="ATP-binding protein; PstABCS is an ATP dependent
                     phosphate uptake system which is responsible for inorganic
                     phosphate uptake during phosphate starvation"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter ATP-binding protein"
                     /protein_id="NP_358846.1"
                     /db_xref="GI:15903296"
                     /db_xref="GeneID:934467"
     gene            complement(1253023..1253826)
                     /gene="pstB"
                     /locus_tag="spr1254"
                     /db_xref="GeneID:934466"
     CDS             complement(1253023..1253826)
                     /gene="pstB"
                     /locus_tag="spr1254"
                     /note="ATP-binding protein; PstABCS is an ATP dependent
                     phosphate uptake system which is responsible for inorganic
                     phosphate uptake during phosphate starvation"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter ATP-binding protein"
                     /protein_id="NP_358847.1"
                     /db_xref="GI:15903297"
                     /db_xref="GeneID:934466"
     gene            complement(1253837..1254721)
                     /gene="pstA"
                     /locus_tag="spr1255"
                     /db_xref="GeneID:934472"
     CDS             complement(1253837..1254721)
                     /gene="pstA"
                     /locus_tag="spr1255"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease"
                     /protein_id="NP_358848.1"
                     /db_xref="GI:15903298"
                     /db_xref="GeneID:934472"
     gene            complement(1254711..1255628)
                     /gene="pstC"
                     /locus_tag="spr1256"
                     /db_xref="GeneID:934470"
     CDS             complement(1254711..1255628)
                     /gene="pstC"
                     /locus_tag="spr1256"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease"
                     /protein_id="NP_358849.1"
                     /db_xref="GI:15903299"
                     /db_xref="GeneID:934470"
     gene            complement(1255628..1256506)
                     /gene="pstS"
                     /locus_tag="spr1257"
                     /db_xref="GeneID:934469"
     CDS             complement(1255628..1256506)
                     /gene="pstS"
                     /locus_tag="spr1257"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate+B766-binding
                     protein"
                     /protein_id="NP_358850.1"
                     /db_xref="GI:15903300"
                     /db_xref="GeneID:934469"
     repeat_region   1256895..1256977
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(1257080..1258384)
                     /locus_tag="spr1258"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934473"
     gene            complement(1258385..1259233)
                     /locus_tag="spr1260"
                     /db_xref="GeneID:934476"
     CDS             complement(1258385..1259233)
                     /locus_tag="spr1260"
                     /note="Similar to E. coli extragenic suppressor protein
                     SuhB"
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="NP_358853.1"
                     /db_xref="GI:15903303"
                     /db_xref="GeneID:934476"
     gene            complement(1259148..1259426)
                     /locus_tag="spr1261"
                     /db_xref="GeneID:934481"
     CDS             complement(1259148..1259426)
                     /locus_tag="spr1261"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358854.1"
                     /db_xref="GI:15903304"
                     /db_xref="GeneID:934481"
     gene            complement(1259426..1259827)
                     /gene="spxA"
                     /locus_tag="spr1262"
                     /gene_synonym="yjbD"
                     /db_xref="GeneID:934475"
     CDS             complement(1259426..1259827)
                     /gene="spxA"
                     /locus_tag="spr1262"
                     /gene_synonym="yjbD"
                     /note="the anti-alpha factor Spx interacts with RNA
                     polymerase alpha subunit C-terminal domain in a region
                     that interacts with the sigma 70 subunit and may interfere
                     with activation of promoters; in Bacillus subtilis this
                     protein is a substrate for ClpXP protease; blocks
                     transcription of the competence regulatory gene encoded by
                     the srf operon; regulates a number of genes involved in
                     thiol homeostasis including trxA and trxB; monomeric
                     member of ArsC family of proteins; does not bind DNA;
                     contains a disulfide bond between C10 and C13 which may
                     sense disulfide stress"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="NP_358855.1"
                     /db_xref="GI:15903305"
                     /db_xref="GeneID:934475"
     gene            complement(1260037..1260687)
                     /locus_tag="spr1263"
                     /db_xref="GeneID:934478"
     CDS             complement(1260037..1260687)
                     /locus_tag="spr1263"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358856.1"
                     /db_xref="GI:15903306"
                     /db_xref="GeneID:934478"
     gene            complement(1260644..1261417)
                     /gene="nagD"
                     /locus_tag="spr1264"
                     /db_xref="GeneID:934502"
     CDS             complement(1260644..1261417)
                     /gene="nagD"
                     /locus_tag="spr1264"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-glucosamine matabolism"
                     /protein_id="NP_358857.1"
                     /db_xref="GI:15903307"
                     /db_xref="GeneID:934502"
     gene            complement(1261428..1262165)
                     /locus_tag="spr1265"
                     /db_xref="GeneID:934474"
     CDS             complement(1261428..1262165)
                     /locus_tag="spr1265"
                     /note="Acyl-ACP thioesterase"
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP thioesterase"
                     /protein_id="NP_358858.1"
                     /db_xref="GI:15903308"
                     /db_xref="GeneID:934474"
     gene            complement(1262170..1263300)
                     /gene="hemN"
                     /locus_tag="spr1266"
                     /db_xref="GeneID:934487"
     CDS             complement(1262170..1263300)
                     /gene="hemN"
                     /locus_tag="spr1266"
                     /EC_number="1.3.3.3"
                     /note="catalyzes the oxygen-independent formation of
                     protoporphyrinogen-IX from coproporphyrinogen-III"
                     /codon_start=1
                     /transl_table=11
                     /product="coproporphyrinogen III oxidase"
                     /protein_id="NP_358859.1"
                     /db_xref="GI:15903309"
                     /db_xref="GeneID:934487"
     gene            complement(1263384..1263773)
                     /locus_tag="spr1267"
                     /db_xref="GeneID:934477"
     CDS             complement(1263384..1263773)
                     /locus_tag="spr1267"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358860.1"
                     /db_xref="GI:15903310"
                     /db_xref="GeneID:934477"
     gene            complement(1263789..1264172)
                     /locus_tag="spr1268"
                     /db_xref="GeneID:934479"
     CDS             complement(1263789..1264172)
                     /locus_tag="spr1268"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358861.1"
                     /db_xref="GI:15903311"
                     /db_xref="GeneID:934479"
     gene            complement(1264173..1264973)
                     /gene="lgt"
                     /locus_tag="spr1269"
                     /db_xref="GeneID:934486"
     CDS             complement(1264173..1264973)
                     /gene="lgt"
                     /locus_tag="spr1269"
                     /EC_number="2.4.99.-"
                     /note="transfers the N-acyl diglyceride moiety to the
                     prospective N-terminal cysteine in prolipoprotein"
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="NP_358862.1"
                     /db_xref="GI:15903312"
                     /db_xref="GeneID:934486"
     gene            complement(1264954..1265904)
                     /gene="hprK"
                     /locus_tag="spr1270"
                     /db_xref="GeneID:934482"
     CDS             complement(1264954..1265904)
                     /gene="hprK"
                     /locus_tag="spr1270"
                     /EC_number="2.7.1.-"
                     /note="catalyzes the phosphorylation of the phosphocarrier
                     protein HPr of the bacterial phosphotransferase system"
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="NP_358863.1"
                     /db_xref="GI:15903313"
                     /db_xref="GeneID:934482"
     gene            complement(1266019..1266219)
                     /gene="rpsU"
                     /locus_tag="spr1271"
                     /db_xref="GeneID:934480"
     CDS             complement(1266019..1266219)
                     /gene="rpsU"
                     /locus_tag="spr1271"
                     /note="a small basic protein that is one of the last in
                     the subunit assembly; omission does not prevent assembly
                     but the subunit is inactive; binds central domain of 16S
                     rRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="NP_358864.1"
                     /db_xref="GI:15903314"
                     /db_xref="GeneID:934480"
     gene            complement(1266335..1267057)
                     /gene="nagB"
                     /locus_tag="spr1272"
                     /db_xref="GeneID:934489"
     CDS             complement(1266335..1267057)
                     /gene="nagB"
                     /locus_tag="spr1272"
                     /EC_number="3.5.99.6"
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate isomerase"
                     /protein_id="NP_358865.1"
                     /db_xref="GI:15903315"
                     /db_xref="GeneID:934489"
     gene            1267181..1268221
                     /gene="queA"
                     /locus_tag="spr1273"
                     /db_xref="GeneID:934484"
     CDS             1267181..1268221
                     /gene="queA"
                     /locus_tag="spr1273"
                     /EC_number="5.-.-.-"
                     /note="Synthesizes oQ from preQ1 in a single
                     S-adenosylmethionine-requiring step"
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosylmethionine:tRNA
                     ribosyltransferase-isomerase"
                     /protein_id="NP_358866.1"
                     /db_xref="GI:15903316"
                     /db_xref="GeneID:934484"
     repeat_region   1268463..1268612
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(1270613..1271164)
                     /locus_tag="spr1275"
                     /db_xref="GeneID:934485"
     CDS             complement(1270613..1271164)
                     /locus_tag="spr1275"
                     /note="alanine acetyl transferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358868.1"
                     /db_xref="GI:15903318"
                     /db_xref="GeneID:934485"
     gene            complement(1271411..1272235)
                     /gene="nadE"
                     /locus_tag="spr1276"
                     /db_xref="GeneID:934488"
     CDS             complement(1271411..1272235)
                     /gene="nadE"
                     /locus_tag="spr1276"
                     /EC_number="6.3.1.5"
                     /note="catalyzes the formation of nicotinamide adenine
                     dinucleotide (NAD) from nicotinic acid adenine
                     dinucleotide (NAAD) using either ammonia or glutamine as
                     the amide donor and ATP; ammonia-utilizing enzymes include
                     the ones from Bacillus and Escherichia coli while
                     glutamine-utilizing enzymes include the Mycobacterial one;
                     forms homodimers"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD synthetase"
                     /protein_id="NP_358869.1"
                     /db_xref="GI:15903319"
                     /db_xref="GeneID:934488"
     gene            complement(1272232..1273692)
                     /locus_tag="spr1277"
                     /db_xref="GeneID:934497"
     CDS             complement(1272232..1273692)
                     /locus_tag="spr1277"
                     /note="catalyzes the formation of 5-phospho-alpha-D-ribose
                     1-diphosphate and nicotinate from nicotinate
                     D-ribonucleotide and diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="NP_358870.1"
                     /db_xref="GI:15903320"
                     /db_xref="GeneID:934497"
     gene            complement(1273808..1274296)
                     /locus_tag="spr1278"
                     /db_xref="GeneID:934492"
     CDS             complement(1273808..1274296)
                     /locus_tag="spr1278"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358871.1"
                     /db_xref="GI:15903321"
                     /db_xref="GeneID:934492"
     gene            complement(1274286..1274525)
                     /locus_tag="spr1279"
                     /db_xref="GeneID:934498"
     CDS             complement(1274286..1274525)
                     /locus_tag="spr1279"
                     /note="transcription regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="NP_358872.1"
                     /db_xref="GI:15903322"
                     /db_xref="GeneID:934498"
     gene            complement(1274880..1275608)
                     /locus_tag="spr1280"
                     /db_xref="GeneID:934501"
     CDS             complement(1274880..1275608)
                     /locus_tag="spr1280"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358873.1"
                     /db_xref="GI:15903323"
                     /db_xref="GeneID:934501"
     gene            complement(1275624..1276346)
                     /gene="ABC-NBD"
                     /locus_tag="spr1281"
                     /db_xref="GeneID:934500"
     CDS             complement(1275624..1276346)
                     /gene="ABC-NBD"
                     /locus_tag="spr1281"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358874.1"
                     /db_xref="GI:15903324"
                     /db_xref="GeneID:934500"
     gene            complement(1276851..1277576)
                     /locus_tag="spr1282"
                     /db_xref="GeneID:934491"
     CDS             complement(1276851..1277576)
                     /locus_tag="spr1282"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358875.1"
                     /db_xref="GI:15903325"
                     /db_xref="GeneID:934491"
     gene            complement(1278165..1279469)
                     /locus_tag="spr1284"
                     /db_xref="GeneID:934494"
     CDS             complement(1278165..1279469)
                     /locus_tag="spr1284"
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="protease"
                     /protein_id="NP_358877.1"
                     /db_xref="GI:15903327"
                     /db_xref="GeneID:934494"
     gene            1280441..1280632
                     /gene="spnIR-truncation"
                     /locus_tag="spr1286"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934505"
     gene            1280629..1281819
                     /gene="spnIM"
                     /locus_tag="spr1287"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934496"
     gene            complement(1282334..1283326)
                     /locus_tag="spr1288"
                     /db_xref="GeneID:934499"
     CDS             complement(1282334..1283326)
                     /locus_tag="spr1288"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358881.1"
                     /db_xref="GI:15903331"
                     /db_xref="GeneID:934499"
     gene            1283480..1285240
                     /gene="ABC-N/P"
                     /locus_tag="spr1289"
                     /db_xref="GeneID:934506"
     CDS             1283480..1285240
                     /gene="ABC-N/P"
                     /locus_tag="spr1289"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_358882.1"
                     /db_xref="GI:15903332"
                     /db_xref="GeneID:934506"
     gene            1285200..1286945
                     /gene="ABC-N/P"
                     /locus_tag="spr1290"
                     /db_xref="GeneID:934504"
     CDS             1285200..1286945
                     /gene="ABC-N/P"
                     /locus_tag="spr1290"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358883.1"
                     /db_xref="GI:15903333"
                     /db_xref="GeneID:934504"
     gene            1286956..1287540
                     /locus_tag="spr1291"
                     /db_xref="GeneID:934511"
     CDS             1286956..1287540
                     /locus_tag="spr1291"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358884.1"
                     /db_xref="GI:15903334"
                     /db_xref="GeneID:934511"
     gene            1287540..1288235
                     /locus_tag="spr1292"
                     /db_xref="GeneID:934527"
     CDS             1287540..1288235
                     /locus_tag="spr1292"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358885.1"
                     /db_xref="GI:15903335"
                     /db_xref="GeneID:934527"
     gene            1288223..1289587
                     /gene="ABC-NBD"
                     /locus_tag="spr1293"
                     /db_xref="GeneID:934510"
     CDS             1288223..1289587
                     /gene="ABC-NBD"
                     /locus_tag="spr1293"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_358886.1"
                     /db_xref="GI:15903336"
                     /db_xref="GeneID:934510"
     repeat_region   complement(1290169..1290268)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            complement(1290375..1290836)
                     /locus_tag="spr1294"
                     /db_xref="GeneID:934512"
     CDS             complement(1290375..1290836)
                     /locus_tag="spr1294"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358887.1"
                     /db_xref="GI:15903337"
                     /db_xref="GeneID:934512"
     gene            complement(1291130..1291498)
                     /locus_tag="spr1296"
                     /db_xref="GeneID:934507"
     CDS             complement(1291130..1291498)
                     /locus_tag="spr1296"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358889.1"
                     /db_xref="GI:15903339"
                     /db_xref="GeneID:934507"
     gene            complement(1291422..1291616)
                     /locus_tag="spr1297"
                     /db_xref="GeneID:934513"
     CDS             complement(1291422..1291616)
                     /locus_tag="spr1297"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358890.1"
                     /db_xref="GI:15903340"
                     /db_xref="GeneID:934513"
     repeat_region   1291657..1291755
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            complement(1291786..1292136)
                     /gene="transposase_E"
                     /locus_tag="spr1298"
                     /db_xref="GeneID:934509"
     CDS             complement(1291786..1292136)
                     /gene="transposase_E"
                     /locus_tag="spr1298"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358891.1"
                     /db_xref="GI:15903341"
                     /db_xref="GeneID:934509"
     gene            complement(1292606..1294168)
                     /gene="guaA"
                     /locus_tag="spr1300"
                     /db_xref="GeneID:934514"
     CDS             complement(1292606..1294168)
                     /gene="guaA"
                     /locus_tag="spr1300"
                     /EC_number="6.3.5.2"
                     /function="converts ATP and xanthosine 5'-phosphate and
                     L-glutamine and water to AMP and pyrophosphate diphosphate
                     and GMP and L-glutamate"
                     /note="contains glutamine-hydrolyzing domain and glutamine
                     amidotransferase; GMP-binding domain; functions to produce
                     GMP from XMP in the IMP pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="GMP synthase"
                     /protein_id="NP_358893.1"
                     /db_xref="GI:15903343"
                     /db_xref="GeneID:934514"
     gene            1294301..1295008
                     /locus_tag="spr1301"
                     /db_xref="GeneID:934515"
     CDS             1294301..1295008
                     /locus_tag="spr1301"
                     /note="Probable transcription regulator, GntR family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358894.1"
                     /db_xref="GI:15903344"
                     /db_xref="GeneID:934515"
     gene            complement(1295051..1296007)
                     /locus_tag="spr1302"
                     /db_xref="GeneID:934519"
     CDS             complement(1295051..1296007)
                     /locus_tag="spr1302"
                     /note="membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358895.1"
                     /db_xref="GI:15903345"
                     /db_xref="GeneID:934519"
     gene            complement(1295956..1296894)
                     /locus_tag="spr1303"
                     /db_xref="GeneID:934520"
     CDS             complement(1295956..1296894)
                     /locus_tag="spr1303"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358896.1"
                     /db_xref="GI:15903346"
                     /db_xref="GeneID:934520"
     gene            complement(1296891..1297631)
                     /gene="cppA"
                     /locus_tag="spr1304"
                     /db_xref="GeneID:934516"
     CDS             complement(1296891..1297631)
                     /gene="cppA"
                     /locus_tag="spr1304"
                     /codon_start=1
                     /transl_table=11
                     /product="C3-degrading proteinase"
                     /protein_id="NP_358897.1"
                     /db_xref="GI:15903347"
                     /db_xref="GeneID:934516"
     gene            complement(1297700..1298335)
                     /locus_tag="spr1305"
                     /db_xref="GeneID:934524"
     CDS             complement(1297700..1298335)
                     /locus_tag="spr1305"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358898.1"
                     /db_xref="GI:15903348"
                     /db_xref="GeneID:934524"
     gene            complement(1298337..1299164)
                     /locus_tag="spr1306"
                     /db_xref="GeneID:934518"
     CDS             complement(1298337..1299164)
                     /locus_tag="spr1306"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_358899.1"
                     /db_xref="GI:15903349"
                     /db_xref="GeneID:934518"
     gene            complement(1299186..1300542)
                     /locus_tag="spr1307"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934521"
     gene            1300763..1301374
                     /gene="def"
                     /locus_tag="spr1310"
                     /db_xref="GeneID:934523"
     CDS             1300763..1301374
                     /gene="def"
                     /locus_tag="spr1310"
                     /EC_number="3.5.1.88"
                     /note="cleaves off formyl group from N-terminal methionine
                     residues of newly synthesized proteins; binds iron(2+)"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="NP_358903.1"
                     /db_xref="GI:15903353"
                     /db_xref="GeneID:934523"
     gene            1301386..1302147
                     /gene="trmH"
                     /locus_tag="spr1311"
                     /db_xref="GeneID:934536"
     CDS             1301386..1302147
                     /gene="trmH"
                     /locus_tag="spr1311"
                     /EC_number="2.1.1.34"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine-2'-O-)-methyltransferase"
                     /protein_id="NP_358904.1"
                     /db_xref="GI:15903354"
                     /db_xref="GeneID:934536"
     gene            complement(1302186..1303097)
                     /gene="trxB"
                     /locus_tag="spr1312"
                     /db_xref="GeneID:934526"
     CDS             complement(1302186..1303097)
                     /gene="trxB"
                     /locus_tag="spr1312"
                     /EC_number="1.8.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin reductase"
                     /protein_id="NP_358905.1"
                     /db_xref="GI:15903355"
                     /db_xref="GeneID:934526"
     gene            complement(1303163..1303399)
                     /locus_tag="spr1313"
                     /db_xref="GeneID:934525"
     CDS             complement(1303163..1303399)
                     /locus_tag="spr1313"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358906.1"
                     /db_xref="GI:15903356"
                     /db_xref="GeneID:934525"
     gene            complement(1303465..1304208)
                     /gene="ABC-NDB"
                     /locus_tag="spr1314"
                     /db_xref="GeneID:934534"
     CDS             complement(1303465..1304208)
                     /gene="ABC-NDB"
                     /locus_tag="spr1314"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358907.1"
                     /db_xref="GI:15903357"
                     /db_xref="GeneID:934534"
     gene            complement(1304208..1305008)
                     /gene="ABC-MSP"
                     /locus_tag="spr1315"
                     /db_xref="GeneID:934533"
     CDS             complement(1304208..1305008)
                     /gene="ABC-MSP"
                     /locus_tag="spr1315"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358908.1"
                     /db_xref="GI:15903358"
                     /db_xref="GeneID:934533"
     gene            complement(1305166..1305522)
                     /locus_tag="spr1316"
                     /db_xref="GeneID:934529"
     CDS             complement(1305166..1305522)
                     /locus_tag="spr1316"
                     /note="Similar to arsenate reductase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358909.1"
                     /db_xref="GI:15903359"
                     /db_xref="GeneID:934529"
     gene            complement(1305516..1306046)
                     /gene="ogt"
                     /locus_tag="spr1317"
                     /db_xref="GeneID:934535"
     CDS             complement(1305516..1306046)
                     /gene="ogt"
                     /locus_tag="spr1317"
                     /EC_number="2.1.1.63"
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--protein-cysteine
                     S-methyltransferase"
                     /protein_id="NP_358910.1"
                     /db_xref="GI:15903360"
                     /db_xref="GeneID:934535"
     gene            complement(1306046..1306540)
                     /locus_tag="spr1318"
                     /db_xref="GeneID:934530"
     CDS             complement(1306046..1306540)
                     /locus_tag="spr1318"
                     /note="acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358911.1"
                     /db_xref="GI:15903361"
                     /db_xref="GeneID:934530"
     gene            1306669..1307121
                     /locus_tag="spr1319"
                     /db_xref="GeneID:934531"
     CDS             1306669..1307121
                     /locus_tag="spr1319"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358912.1"
                     /db_xref="GI:15903362"
                     /db_xref="GeneID:934531"
     gene            1307118..1307765
                     /locus_tag="spr1320"
                     /db_xref="GeneID:934541"
     CDS             1307118..1307765
                     /locus_tag="spr1320"
                     /note="Similar to hemolysin III"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="NP_358913.1"
                     /db_xref="GI:15903363"
                     /db_xref="GeneID:934541"
     gene            complement(1307786..1308367)
                     /locus_tag="spr1321"
                     /db_xref="GeneID:934544"
     CDS             complement(1307786..1308367)
                     /locus_tag="spr1321"
                     /note="with PdxST is involved in the biosynthesis of
                     pyridoxal 5'-phosphate; PdxT catalyzes the hydrolysis of
                     glutamine to glutamate and ammonia; PdxS utilizes the
                     ammonia to synthesize pyridoxal 5'-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase subunit PdxT"
                     /protein_id="NP_358914.1"
                     /db_xref="GI:15903364"
                     /db_xref="GeneID:934544"
     gene            complement(1308368..1309261)
                     /gene="pdx1"
                     /locus_tag="spr1322"
                     /db_xref="GeneID:934532"
     CDS             complement(1308368..1309261)
                     /gene="pdx1"
                     /locus_tag="spr1322"
                     /note="with PdxT forms pyridoxal 5'-phosphate from
                     glutamine, either ribose 5-phosphate or ribulose
                     5-phosphate, and either glyceraldehyde 3-phosphate or
                     dihydroxyacetone phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal biosynthesis lyase PdxS"
                     /protein_id="NP_358915.1"
                     /db_xref="GI:15903365"
                     /db_xref="GeneID:934532"
     gene            complement(1309395..1310774)
                     /gene="nox"
                     /locus_tag="spr1323"
                     /db_xref="GeneID:934540"
     CDS             complement(1309395..1310774)
                     /gene="nox"
                     /locus_tag="spr1323"
                     /EC_number="1.6.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="NP_358916.1"
                     /db_xref="GI:15903366"
                     /db_xref="GeneID:934540"
     gene            1311068..1311991
                     /gene="apbE"
                     /locus_tag="spr1324"
                     /db_xref="GeneID:934537"
     CDS             1311068..1311991
                     /gene="apbE"
                     /locus_tag="spr1324"
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine biosynthesis protein ApbE"
                     /protein_id="NP_358917.1"
                     /db_xref="GI:15903367"
                     /db_xref="GeneID:934537"
     gene            1312051..1312656
                     /locus_tag="spr1325"
                     /db_xref="GeneID:934542"
     CDS             1312051..1312656
                     /locus_tag="spr1325"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358918.1"
                     /db_xref="GI:15903368"
                     /db_xref="GeneID:934542"
     gene            1312674..1313918
                     /locus_tag="spr1326"
                     /db_xref="GeneID:934543"
     CDS             1312674..1313918
                     /locus_tag="spr1326"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_358919.1"
                     /db_xref="GI:15903369"
                     /db_xref="GeneID:934543"
     gene            complement(1314035..1314292)
                     /locus_tag="spr1327"
                     /db_xref="GeneID:934539"
     CDS             complement(1314035..1314292)
                     /locus_tag="spr1327"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358920.1"
                     /db_xref="GI:15903370"
                     /db_xref="GeneID:934539"
     gene            complement(1314334..1316370)
                     /gene="glyS"
                     /locus_tag="spr1328"
                     /db_xref="GeneID:934538"
     CDS             complement(1314334..1316370)
                     /gene="glyS"
                     /locus_tag="spr1328"
                     /EC_number="6.1.1.14"
                     /note="glycine--tRNA ligase beta chain; glyS; class II
                     aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2);
                     catalyzes a two-step reaction; first charging a glycine
                     molecule by linking the carboxyl group to the
                     alpha-phosphate of ATP; second by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-tRNA synthetase subunit beta"
                     /protein_id="NP_358921.1"
                     /db_xref="GI:15903371"
                     /db_xref="GeneID:934538"
     gene            complement(1316630..1317547)
                     /gene="glyQ"
                     /locus_tag="spr1329"
                     /db_xref="GeneID:934548"
     CDS             complement(1316630..1317547)
                     /gene="glyQ"
                     /locus_tag="spr1329"
                     /EC_number="6.1.1.14"
                     /note="glycine--tRNA ligase alpha chain; GlyRS; class II
                     aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2);
                     catalyzes a two-step reaction; first charging a glycine
                     molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP; second by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-tRNA synthetase subunit alpha"
                     /protein_id="NP_358922.1"
                     /db_xref="GI:15903372"
                     /db_xref="GeneID:934548"
     gene            complement(1317741..1318501)
                     /locus_tag="spr1330"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934545"
     gene            complement(1318774..1319616)
                     /locus_tag="spr1332"
                     /db_xref="GeneID:934550"
     CDS             complement(1318774..1319616)
                     /locus_tag="spr1332"
                     /note="oxidoreductase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358925.1"
                     /db_xref="GI:15903375"
                     /db_xref="GeneID:934550"
     gene            complement(1319730..1321121)
                     /gene="pgdA"
                     /locus_tag="spr1333"
                     /db_xref="GeneID:934547"
     CDS             complement(1319730..1321121)
                     /gene="pgdA"
                     /locus_tag="spr1333"
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan GlcNAc deacetylase"
                     /protein_id="NP_358926.1"
                     /db_xref="GI:15903376"
                     /db_xref="GeneID:934547"
     repeat_region   1321262..1321366
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1321356..1321733)
                     /locus_tag="spr1334"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934553"
     gene            1321864..1322925
                     /gene="mocA"
                     /locus_tag="spr1335"
                     /db_xref="GeneID:934555"
     CDS             1321864..1322925
                     /gene="mocA"
                     /locus_tag="spr1335"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_358928.1"
                     /db_xref="GI:15903378"
                     /db_xref="GeneID:934555"
     gene            1322922..1324004
                     /gene="DEAD/H"
                     /locus_tag="spr1336"
                     /db_xref="GeneID:934554"
     CDS             1322922..1324004
                     /gene="DEAD/H"
                     /locus_tag="spr1336"
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD RNA helicase"
                     /protein_id="NP_358929.1"
                     /db_xref="GI:15903379"
                     /db_xref="GeneID:934554"
     gene            complement(1324655..1325487)
                     /gene="IS861-truncation"
                     /locus_tag="spr1339"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934552"
     repeat_region   1326339..1326442
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     repeat_region   1326676..1326720
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     repeat_region   complement(1326740..1326838)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1326964..1328160)
                     /gene="tuf"
                     /locus_tag="spr1343"
                     /db_xref="GeneID:934560"
     CDS             complement(1326964..1328160)
                     /gene="tuf"
                     /locus_tag="spr1343"
                     /EC_number="3.6.5.3"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="NP_358936.1"
                     /db_xref="GI:15903386"
                     /db_xref="GeneID:934560"
     repeat_region   complement(1328399..1328505)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   1328504..1328527
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            complement(1329082..1329951)
                     /gene="glpF"
                     /locus_tag="spr1344"
                     /db_xref="GeneID:934564"
     CDS             complement(1329082..1329951)
                     /gene="glpF"
                     /locus_tag="spr1344"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein"
                     /protein_id="NP_358937.1"
                     /db_xref="GI:15903387"
                     /db_xref="GeneID:934564"
     gene            complement(1330175..1330783)
                     /locus_tag="spr1345"
                     /db_xref="GeneID:934589"
     CDS             complement(1330175..1330783)
                     /locus_tag="spr1345"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor family protein"
                     /protein_id="NP_358938.1"
                     /db_xref="GI:15903388"
                     /db_xref="GeneID:934589"
     gene            complement(1330741..1331853)
                     /locus_tag="spr1346"
                     /db_xref="GeneID:934559"
     CDS             complement(1330741..1331853)
                     /locus_tag="spr1346"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358939.1"
                     /db_xref="GI:15903389"
                     /db_xref="GeneID:934559"
     gene            complement(1331958..1332212)
                     /locus_tag="spr1347"
                     /db_xref="GeneID:934567"
     CDS             complement(1331958..1332212)
                     /locus_tag="spr1347"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358940.1"
                     /db_xref="GI:15903390"
                     /db_xref="GeneID:934567"
     gene            complement(1332206..1332448)
                     /locus_tag="spr1348"
                     /db_xref="GeneID:934562"
     CDS             complement(1332206..1332448)
                     /locus_tag="spr1348"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358941.1"
                     /db_xref="GI:15903391"
                     /db_xref="GeneID:934562"
     gene            complement(1333089..1333353)
                     /gene="transposase_A"
                     /locus_tag="spr1350"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934566"
     gene            1333648..1335366
                     /gene="pgm"
                     /locus_tag="spr1351"
                     /db_xref="GeneID:934575"
     CDS             1333648..1335366
                     /gene="pgm"
                     /locus_tag="spr1351"
                     /EC_number="5.4.2.8"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucomutase"
                     /protein_id="NP_358944.1"
                     /db_xref="GI:15903394"
                     /db_xref="GeneID:934575"
     gene            1335477..1335824
                     /gene="bta"
                     /locus_tag="spr1352"
                     /db_xref="GeneID:934565"
     CDS             1335477..1335824
                     /gene="bta"
                     /locus_tag="spr1352"
                     /codon_start=1
                     /transl_table=11
                     /product="bacterocin transport accessory protein"
                     /protein_id="NP_358945.1"
                     /db_xref="GI:15903395"
                     /db_xref="GeneID:934565"
     gene            complement(1336103..1336939)
                     /gene="glnH"
                     /locus_tag="spr1353"
                     /db_xref="GeneID:934569"
     CDS             complement(1336103..1336939)
                     /gene="glnH"
                     /locus_tag="spr1353"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter amino acid-binding
                     protein"
                     /protein_id="NP_358946.1"
                     /db_xref="GI:15903396"
                     /db_xref="GeneID:934569"
     gene            complement(1336952..1337581)
                     /gene="glnQ"
                     /locus_tag="spr1354"
                     /db_xref="GeneID:934568"
     CDS             complement(1336952..1337581)
                     /gene="glnQ"
                     /locus_tag="spr1354"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="NP_358947.1"
                     /db_xref="GI:15903397"
                     /db_xref="GeneID:934568"
     gene            complement(1337591..1338289)
                     /gene="glnP"
                     /locus_tag="spr1355"
                     /db_xref="GeneID:934570"
     CDS             complement(1337591..1338289)
                     /gene="glnP"
                     /locus_tag="spr1355"
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="NP_358948.1"
                     /db_xref="GI:15903398"
                     /db_xref="GeneID:934570"
     gene            complement(1338378..1339622)
                     /locus_tag="spr1356"
                     /db_xref="GeneID:934578"
     CDS             complement(1338378..1339622)
                     /locus_tag="spr1356"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358949.1"
                     /db_xref="GI:15903399"
                     /db_xref="GeneID:934578"
     gene            complement(1339597..1340763)
                     /locus_tag="spr1357"
                     /db_xref="GeneID:934574"
     CDS             complement(1339597..1340763)
                     /locus_tag="spr1357"
                     /note="membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358950.1"
                     /db_xref="GI:15903400"
                     /db_xref="GeneID:934574"
     gene            1340907..1341920
                     /locus_tag="spr1358"
                     /db_xref="GeneID:934572"
     CDS             1340907..1341920
                     /locus_tag="spr1358"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358951.1"
                     /db_xref="GI:15903401"
                     /db_xref="GeneID:934572"
     gene            complement(1341965..1342384)
                     /gene="atpC"
                     /locus_tag="spr1359"
                     /db_xref="GeneID:934577"
     CDS             complement(1341965..1342384)
                     /gene="atpC"
                     /locus_tag="spr1359"
                     /EC_number="3.6.3.14"
                     /note="part of catalytic core of ATP synthase;
                     alpha(3)beta(3)gamma(1)delta(1)epsilon(1); involved in
                     producing ATP from ADP in the presence of the proton
                     motive force across the membrane"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit epsilon"
                     /protein_id="NP_358952.1"
                     /db_xref="GI:15903402"
                     /db_xref="GeneID:934577"
     gene            complement(1342395..1343801)
                     /gene="atpD"
                     /locus_tag="spr1360"
                     /db_xref="GeneID:934571"
     CDS             complement(1342395..1343801)
                     /gene="atpD"
                     /locus_tag="spr1360"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. The beta chain is a
                     regulatory subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit beta"
                     /protein_id="NP_358953.1"
                     /db_xref="GI:15903403"
                     /db_xref="GeneID:934571"
     gene            complement(1343887..1344765)
                     /gene="atpG"
                     /locus_tag="spr1361"
                     /db_xref="GeneID:934573"
     CDS             complement(1343887..1344765)
                     /gene="atpG"
                     /locus_tag="spr1361"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. The gamma chain is a
                     regulatory subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit gamma"
                     /protein_id="NP_358954.1"
                     /db_xref="GI:15903404"
                     /db_xref="GeneID:934573"
     gene            complement(1344781..1346286)
                     /gene="atpA"
                     /locus_tag="spr1362"
                     /db_xref="GeneID:934581"
     CDS             complement(1344781..1346286)
                     /gene="atpA"
                     /locus_tag="spr1362"
                     /EC_number="3.6.3.14"
                     /note="produces ATP from ADP in the presence of a proton
                     gradient across the membrane; the alpha chain is a
                     catalytic subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit alpha"
                     /protein_id="NP_358955.1"
                     /db_xref="GI:15903405"
                     /db_xref="GeneID:934581"
     gene            complement(1346301..1346837)
                     /gene="atpH"
                     /locus_tag="spr1363"
                     /db_xref="GeneID:934579"
     CDS             complement(1346301..1346837)
                     /gene="atpH"
                     /locus_tag="spr1363"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane; the delta subunit is part of
                     the catalytic core of the ATP synthase complex"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit delta"
                     /protein_id="NP_358956.1"
                     /db_xref="GI:15903406"
                     /db_xref="GeneID:934579"
     gene            complement(1346837..1347331)
                     /gene="atpF"
                     /locus_tag="spr1364"
                     /db_xref="GeneID:934576"
     CDS             complement(1346837..1347331)
                     /gene="atpF"
                     /locus_tag="spr1364"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit B is part of the
                     membrane proton channel."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit B"
                     /protein_id="NP_358957.1"
                     /db_xref="GI:15903407"
                     /db_xref="GeneID:934576"
     gene            complement(1347345..1348061)
                     /gene="atpB"
                     /locus_tag="spr1365"
                     /db_xref="GeneID:934583"
     CDS             complement(1347345..1348061)
                     /gene="atpB"
                     /locus_tag="spr1365"
                     /EC_number="3.6.3.14"
                     /note="Produces ATP from ADP in the presence of a proton
                     gradient across the membrane. Subunit A is part of the
                     membrane proton channel F0"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit A"
                     /protein_id="NP_358958.1"
                     /db_xref="GI:15903408"
                     /db_xref="GeneID:934583"
     gene            complement(1348096..1348296)
                     /gene="atpE"
                     /locus_tag="spr1366"
                     /db_xref="GeneID:934580"
     CDS             complement(1348096..1348296)
                     /gene="atpE"
                     /locus_tag="spr1366"
                     /EC_number="3.6.3.14"
                     /note="produces ATP from ADP in the presence of a proton
                     gradient across the membrane; subunit C is part of the
                     membrane proton channel F0"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0F1 subunit C"
                     /protein_id="NP_358959.1"
                     /db_xref="GI:15903409"
                     /db_xref="GeneID:934580"
     gene            complement(1348371..1349378)
                     /gene="IS1239"
                     /locus_tag="spr1367"
                     /db_xref="GeneID:934582"
     CDS             complement(1348371..1349378)
                     /gene="IS1239"
                     /locus_tag="spr1367"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_358960.1"
                     /db_xref="GI:15903410"
                     /db_xref="GeneID:934582"
     gene            complement(1349823..1350305)
                     /locus_tag="spr1368"
                     /db_xref="GeneID:934587"
     CDS             complement(1349823..1350305)
                     /locus_tag="spr1368"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358961.1"
                     /db_xref="GI:15903411"
                     /db_xref="GeneID:934587"
     repeat_region   complement(1350234..1350325)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_c"
     repeat_region   complement(1350340..1350711)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbbbbbba"
     gene            complement(1350774..1351265)
                     /gene="greA"
                     /locus_tag="spr1369"
                     /db_xref="GeneID:934588"
     CDS             complement(1350774..1351265)
                     /gene="greA"
                     /locus_tag="spr1369"
                     /note="necessary for efficient RNA polymerase
                     transcription elongation past template-encoded arresting
                     sites; arresting sites in DNA have the property of
                     trapping a certain fraction of elongating RNA polymerases
                     that pass through, resulting in locked ternary complexes.
                     Cleavage of the nascent transcript by cleavage factors
                     such as GreA or GreB allows the resumption of elongation
                     from the new 3'terminus"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="NP_358962.1"
                     /db_xref="GI:15903412"
                     /db_xref="GeneID:934588"
     gene            complement(1351327..1352982)
                     /locus_tag="spr1370"
                     /db_xref="GeneID:934585"
     CDS             complement(1351327..1352982)
                     /locus_tag="spr1370"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358963.1"
                     /db_xref="GI:15903413"
                     /db_xref="GeneID:934585"
     gene            complement(1353063..1353557)
                     /locus_tag="spr1371"
                     /db_xref="GeneID:934584"
     CDS             complement(1353063..1353557)
                     /locus_tag="spr1371"
                     /note="acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358964.1"
                     /db_xref="GI:15903414"
                     /db_xref="GeneID:934584"
     gene            complement(1353554..1354018)
                     /locus_tag="spr1372"
                     /db_xref="GeneID:934592"
     CDS             complement(1353554..1354018)
                     /locus_tag="spr1372"
                     /note="N-terminal acetyltransferase related protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358965.1"
                     /db_xref="GI:15903415"
                     /db_xref="GeneID:934592"
     gene            complement(1354028..1355362)
                     /gene="murC"
                     /locus_tag="spr1373"
                     /db_xref="GeneID:934586"
     CDS             complement(1354028..1355362)
                     /gene="murC"
                     /locus_tag="spr1373"
                     /EC_number="6.3.2.8"
                     /note="Catalyzes the formation of
                     UDP-N-acetylmuramoyl-L-alanine from UDP-N-acetylmuramate
                     and L-alanine in peptidoglycan synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="NP_358966.1"
                     /db_xref="GI:15903416"
                     /db_xref="GeneID:934586"
     gene            complement(1355373..1355990)
                     /locus_tag="spr1374"
                     /db_xref="GeneID:934590"
     CDS             complement(1355373..1355990)
                     /locus_tag="spr1374"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358967.1"
                     /db_xref="GI:15903417"
                     /db_xref="GeneID:934590"
     gene            complement(1356038..1359136)
                     /gene="snf"
                     /locus_tag="spr1375"
                     /db_xref="GeneID:934596"
     CDS             complement(1356038..1359136)
                     /gene="snf"
                     /locus_tag="spr1375"
                     /codon_start=1
                     /transl_table=11
                     /product="Snf2 family protein"
                     /protein_id="NP_358968.1"
                     /db_xref="GI:15903418"
                     /db_xref="GeneID:934596"
     gene            complement(1359229..1360395)
                     /gene="patB"
                     /locus_tag="spr1376"
                     /db_xref="GeneID:934591"
     CDS             complement(1359229..1360395)
                     /gene="patB"
                     /locus_tag="spr1376"
                     /EC_number="2.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase, class II"
                     /protein_id="NP_358969.1"
                     /db_xref="GI:15903419"
                     /db_xref="GeneID:934591"
     gene            complement(1360403..1361497)
                     /gene="metB"
                     /locus_tag="spr1377"
                     /db_xref="GeneID:934621"
     CDS             complement(1360403..1361497)
                     /gene="metB"
                     /locus_tag="spr1377"
                     /EC_number="2.5.1.48"
                     /note="catalyzes the formation of cystathionine from
                     L-cysteine and O-succinyl-L-homoserine"
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="NP_358970.1"
                     /db_xref="GI:15903420"
                     /db_xref="GeneID:934621"
     gene            complement(1361655..1362777)
                     /gene="ABC-MSP-truncation"
                     /locus_tag="spr1378"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934600"
     gene            complement(1363510..1365468)
                     /gene="aliB"
                     /locus_tag="spr1382"
                     /db_xref="GeneID:934595"
     CDS             complement(1363510..1365468)
                     /gene="aliB"
                     /locus_tag="spr1382"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_358975.1"
                     /db_xref="GI:15903425"
                     /db_xref="GeneID:934595"
     gene            complement(1365671..1367293)
                     /gene="PST_transporter"
                     /locus_tag="spr1383"
                     /db_xref="GeneID:934598"
     CDS             complement(1365671..1367293)
                     /gene="PST_transporter"
                     /locus_tag="spr1383"
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="NP_358976.1"
                     /db_xref="GI:15903426"
                     /db_xref="GeneID:934598"
     gene            1367399..1368844
                     /gene="murE"
                     /locus_tag="spr1384"
                     /db_xref="GeneID:934603"
     CDS             1367399..1368844
                     /gene="murE"
                     /locus_tag="spr1384"
                     /EC_number="6.3.2.13"
                     /note="involved in cell wall formation; peptidoglycan
                     synthesis; cytoplasmic enzyme; catalyzes the addition of
                     lysine to UDP-N-acetylmuramoyl-L-alanyl-D-glutamate
                     forming UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--L-lysine
                     ligase"
                     /protein_id="NP_358977.1"
                     /db_xref="GI:15903427"
                     /db_xref="GeneID:934603"
     gene            complement(1368890..1369084)
                     /locus_tag="spr1385"
                     /db_xref="GeneID:934607"
     CDS             complement(1368890..1369084)
                     /locus_tag="spr1385"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358978.1"
                     /db_xref="GI:15903428"
                     /db_xref="GeneID:934607"
     gene            complement(1369185..1369780)
                     /locus_tag="spr1386"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934599"
     gene            complement(1369817..1370329)
                     /locus_tag="spr1388"
                     /db_xref="GeneID:934601"
     CDS             complement(1369817..1370329)
                     /locus_tag="spr1388"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358981.1"
                     /db_xref="GI:15903431"
                     /db_xref="GeneID:934601"
     gene            complement(1370416..1371351)
                     /gene="ppaC"
                     /locus_tag="spr1389"
                     /db_xref="GeneID:934602"
     CDS             complement(1370416..1371351)
                     /gene="ppaC"
                     /locus_tag="spr1389"
                     /EC_number="3.6.1.1"
                     /note="catalyzes the hydrolysis of pyrophosphate to
                     phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="NP_358982.1"
                     /db_xref="GI:15903432"
                     /db_xref="GeneID:934602"
     gene            complement(1371422..1371721)
                     /locus_tag="spr1390"
                     /db_xref="GeneID:934610"
     CDS             complement(1371422..1371721)
                     /locus_tag="spr1390"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358983.1"
                     /db_xref="GI:15903433"
                     /db_xref="GeneID:934610"
     gene            complement(1371711..1372460)
                     /locus_tag="spr1391"
                     /db_xref="GeneID:934604"
     CDS             complement(1371711..1372460)
                     /locus_tag="spr1391"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358984.1"
                     /db_xref="GI:15903434"
                     /db_xref="GeneID:934604"
     gene            complement(1372514..1372900)
                     /locus_tag="spr1392"
                     /db_xref="GeneID:934608"
     CDS             complement(1372514..1372900)
                     /locus_tag="spr1392"
                     /note="Similar to general stress protein GSP13 from
                     Lactococcus lactis subsp. lactis and Bacillus subtilis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358985.1"
                     /db_xref="GI:15903435"
                     /db_xref="GeneID:934608"
     gene            complement(1372875..1374275)
                     /locus_tag="spr1393"
                     /db_xref="GeneID:934612"
     CDS             complement(1372875..1374275)
                     /locus_tag="spr1393"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein/peptidyl-prolyl cis-trans
                     isomerase"
                     /protein_id="NP_358986.1"
                     /db_xref="GI:15903436"
                     /db_xref="GeneID:934612"
     gene            complement(1374570..1374809)
                     /gene="rpsR"
                     /locus_tag="spr1394"
                     /db_xref="GeneID:934606"
     CDS             complement(1374570..1374809)
                     /gene="rpsR"
                     /locus_tag="spr1394"
                     /note="binds as a heterodimer with protein S6 to the
                     central domain of the 16S rRNA; helps stabilize the
                     platform of the 30S subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="NP_358987.1"
                     /db_xref="GI:15903437"
                     /db_xref="GeneID:934606"
     gene            complement(1374841..1375311)
                     /gene="ssbA"
                     /locus_tag="spr1395"
                     /db_xref="GeneID:934609"
     CDS             complement(1374841..1375311)
                     /gene="ssbA"
                     /locus_tag="spr1395"
                     /note="binds to single stranded DNA and may facilitate the
                     binding and interaction of other proteins to DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="NP_358988.1"
                     /db_xref="GI:15903438"
                     /db_xref="GeneID:934609"
     gene            complement(1375323..1375613)
                     /gene="rpsF"
                     /locus_tag="spr1396"
                     /db_xref="GeneID:934613"
     CDS             complement(1375323..1375613)
                     /gene="rpsF"
                     /locus_tag="spr1396"
                     /note="binds cooperatively with S18 to the S15-16S
                     complex, allowing platform assembly to continue with S11
                     and S21"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="NP_358989.1"
                     /db_xref="GI:15903439"
                     /db_xref="GeneID:934613"
     gene            complement(1375766..1377109)
                     /gene="asnC"
                     /locus_tag="spr1397"
                     /db_xref="GeneID:934611"
     CDS             complement(1375766..1377109)
                     /gene="asnC"
                     /locus_tag="spr1397"
                     /EC_number="6.1.1.22"
                     /note="catalyzes a two-step reaction, first charging an
                     asparagine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginyl-tRNA synthetase"
                     /protein_id="NP_358990.1"
                     /db_xref="GI:15903440"
                     /db_xref="GeneID:934611"
     gene            complement(1377128..1377499)
                     /locus_tag="spr1398"
                     /db_xref="GeneID:934615"
     CDS             complement(1377128..1377499)
                     /locus_tag="spr1398"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358991.1"
                     /db_xref="GI:15903441"
                     /db_xref="GeneID:934615"
     gene            complement(1377486..1378673)
                     /gene="aspB"
                     /locus_tag="spr1399"
                     /db_xref="GeneID:934622"
     CDS             complement(1377486..1378673)
                     /gene="aspB"
                     /locus_tag="spr1399"
                     /EC_number="2.6.1.1"
                     /note="catalyzes the formation of oxalozcetate and
                     L-glutamate from L-aspartate and 2-oxoglutarate"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate aminotransferase"
                     /protein_id="NP_358992.1"
                     /db_xref="GI:15903442"
                     /db_xref="GeneID:934622"
     gene            complement(1378670..1379158)
                     /locus_tag="spr1400"
                     /db_xref="GeneID:934614"
     CDS             complement(1378670..1379158)
                     /locus_tag="spr1400"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358993.1"
                     /db_xref="GI:15903443"
                     /db_xref="GeneID:934614"
     gene            1379398..1380027
                     /locus_tag="spr1402"
                     /db_xref="GeneID:934619"
     CDS             1379398..1380027
                     /locus_tag="spr1402"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358995.1"
                     /db_xref="GI:15903445"
                     /db_xref="GeneID:934619"
     gene            complement(1380265..1387920)
                     /locus_tag="spr1403"
                     /db_xref="GeneID:934616"
     CDS             complement(1380265..1387920)
                     /locus_tag="spr1403"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358996.1"
                     /db_xref="GI:15903446"
                     /db_xref="GeneID:934616"
     gene            1388112..1389620
                     /locus_tag="spr1404"
                     /db_xref="GeneID:934617"
     CDS             1388112..1389620
                     /locus_tag="spr1404"
                     /note="Mga-like regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358997.1"
                     /db_xref="GI:15903447"
                     /db_xref="GeneID:934617"
     gene            complement(1389671..1390399)
                     /locus_tag="spr1405"
                     /db_xref="GeneID:934628"
     CDS             complement(1389671..1390399)
                     /locus_tag="spr1405"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358998.1"
                     /db_xref="GI:15903448"
                     /db_xref="GeneID:934628"
     gene            complement(1390478..1390657)
                     /locus_tag="spr1406"
                     /db_xref="GeneID:934620"
     CDS             complement(1390478..1390657)
                     /locus_tag="spr1406"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_358999.1"
                     /db_xref="GI:15903449"
                     /db_xref="GeneID:934620"
     repeat_region   complement(1390706..1390810)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1390809..1392404)
                     /locus_tag="spr1407"
                     /db_xref="GeneID:934168"
     CDS             complement(1390809..1392404)
                     /locus_tag="spr1407"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359000.1"
                     /db_xref="GI:15903450"
                     /db_xref="GeneID:934168"
     gene            complement(1392416..1392826)
                     /gene="def"
                     /locus_tag="spr1408"
                     /db_xref="GeneID:934624"
     CDS             complement(1392416..1392826)
                     /gene="def"
                     /locus_tag="spr1408"
                     /EC_number="3.5.1.88"
                     /note="cleaves off formyl group from N-terminal methionine
                     residues of newly synthesized proteins; binds iron(2+)"
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="NP_359001.1"
                     /db_xref="GI:15903451"
                     /db_xref="GeneID:934624"
     gene            complement(1392942..1393733)
                     /locus_tag="spr1409"
                     /db_xref="GeneID:934623"
     CDS             complement(1392942..1393733)
                     /locus_tag="spr1409"
                     /note="YghU; B2989; one of eight glutathione transferases
                     from E. coli"
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase YghU"
                     /protein_id="NP_359002.1"
                     /db_xref="GI:15903452"
                     /db_xref="GeneID:934623"
     gene            complement(1393746..1396442)
                     /gene="pacL"
                     /locus_tag="spr1410"
                     /db_xref="GeneID:934079"
     CDS             complement(1393746..1396442)
                     /gene="pacL"
                     /locus_tag="spr1410"
                     /EC_number="3.6.3.10"
                     /note="calcium transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="calcium transporter P-type ATPase"
                     /protein_id="NP_359003.1"
                     /db_xref="GI:15903453"
                     /db_xref="GeneID:934079"
     gene            1396746..1397930
                     /locus_tag="spr1411"
                     /db_xref="GeneID:934626"
     CDS             1396746..1397930
                     /locus_tag="spr1411"
                     /note="Probable cation transporter"
                     /codon_start=1
                     /transl_table=11
                     /product="cation efflux family protein"
                     /protein_id="NP_359004.1"
                     /db_xref="GI:15903454"
                     /db_xref="GeneID:934626"
     gene            complement(1398073..1399944)
                     /gene="ABC-NBD"
                     /locus_tag="spr1412"
                     /db_xref="GeneID:934166"
     CDS             complement(1398073..1399944)
                     /gene="ABC-NBD"
                     /locus_tag="spr1412"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359005.1"
                     /db_xref="GI:15903455"
                     /db_xref="GeneID:934166"
     gene            complement(1399941..1401140)
                     /gene="cca"
                     /locus_tag="spr1413"
                     /db_xref="GeneID:934161"
     CDS             complement(1399941..1401140)
                     /gene="cca"
                     /locus_tag="spr1413"
                     /note="catalyzes the addition and repair of the
                     3'-terminal CCA sequence in tRNA; these proteins belong to
                     the CCA-adding enzyme subfamily 2 which does not have
                     phosphohydrolase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA CCA-pyrophosphorylase"
                     /protein_id="NP_359006.1"
                     /db_xref="GI:15903456"
                     /db_xref="GeneID:934161"
     gene            complement(1401137..1401904)
                     /gene="dapB"
                     /locus_tag="spr1414"
                     /db_xref="GeneID:934164"
     CDS             complement(1401137..1401904)
                     /gene="dapB"
                     /locus_tag="spr1414"
                     /note="catalyzes the reduction of 2,3-dihydrodipicolinate
                     to 2,3,4,5-tetrahydrodipicolinate in lysine and
                     diaminopimelate biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate reductase"
                     /protein_id="NP_359007.1"
                     /db_xref="GI:15903457"
                     /db_xref="GeneID:934164"
     gene            complement(1402181..1403029)
                     /locus_tag="spr1415"
                     /db_xref="GeneID:934169"
     CDS             complement(1402181..1403029)
                     /locus_tag="spr1415"
                     /note="Similar to DegV of B.subtilis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359008.1"
                     /db_xref="GI:15903458"
                     /db_xref="GeneID:934169"
     gene            complement(1403031..1403417)
                     /locus_tag="spr1416"
                     /db_xref="GeneID:933090"
     CDS             complement(1403031..1403417)
                     /locus_tag="spr1416"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359009.1"
                     /db_xref="GI:15903459"
                     /db_xref="GeneID:933090"
     gene            complement(1403479..1404831)
                     /gene="glmM"
                     /locus_tag="spr1417"
                     /db_xref="GeneID:934084"
     CDS             complement(1403479..1404831)
                     /gene="glmM"
                     /locus_tag="spr1417"
                     /EC_number="5.4.2.3"
                     /note="catalyzes the conversion of glucosamine-6-phosphate
                     to glucosamine-1-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="NP_359010.1"
                     /db_xref="GI:15903460"
                     /db_xref="GeneID:934084"
     gene            complement(1404855..1405634)
                     /locus_tag="spr1418"
                     /db_xref="GeneID:933941"
     CDS             complement(1404855..1405634)
                     /locus_tag="spr1418"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359011.1"
                     /db_xref="GI:15903461"
                     /db_xref="GeneID:933941"
     gene            complement(1405621..1406499)
                     /locus_tag="spr1419"
                     /db_xref="GeneID:934085"
     CDS             complement(1405621..1406499)
                     /locus_tag="spr1419"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359012.1"
                     /db_xref="GI:15903462"
                     /db_xref="GeneID:934085"
     gene            complement(1406396..1406569)
                     /locus_tag="spr1420"
                     /db_xref="GeneID:933883"
     CDS             complement(1406396..1406569)
                     /locus_tag="spr1420"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359013.1"
                     /db_xref="GI:15903463"
                     /db_xref="GeneID:933883"
     gene            1406614..1407582
                     /gene="trxB"
                     /locus_tag="spr1421"
                     /db_xref="GeneID:934042"
     CDS             1406614..1407582
                     /gene="trxB"
                     /locus_tag="spr1421"
                     /EC_number="1.8.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulphide oxidoreductase"
                     /protein_id="NP_359014.1"
                     /db_xref="GI:15903464"
                     /db_xref="GeneID:934042"
     gene            complement(1407616..1408527)
                     /locus_tag="spr1422"
                     /db_xref="GeneID:934044"
     CDS             complement(1407616..1408527)
                     /locus_tag="spr1422"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359015.1"
                     /db_xref="GI:15903465"
                     /db_xref="GeneID:934044"
     gene            complement(1408524..1409501)
                     /locus_tag="spr1423"
                     /db_xref="GeneID:934065"
     CDS             complement(1408524..1409501)
                     /locus_tag="spr1423"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359016.1"
                     /db_xref="GI:15903466"
                     /db_xref="GeneID:934065"
     gene            complement(1409498..1410388)
                     /locus_tag="spr1424"
                     /db_xref="GeneID:934082"
     CDS             complement(1409498..1410388)
                     /locus_tag="spr1424"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359017.1"
                     /db_xref="GI:15903467"
                     /db_xref="GeneID:934082"
     gene            complement(1410440..1410820)
                     /gene="aldR"
                     /locus_tag="spr1425"
                     /db_xref="GeneID:933389"
     CDS             complement(1410440..1410820)
                     /gene="aldR"
                     /locus_tag="spr1425"
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease L-PSP"
                     /protein_id="NP_359018.1"
                     /db_xref="GI:15903468"
                     /db_xref="GeneID:933389"
     gene            complement(1410831..1411424)
                     /gene="engB"
                     /locus_tag="spr1426"
                     /gene_synonym="yihA; ysxC"
                     /db_xref="GeneID:933284"
     CDS             complement(1410831..1411424)
                     /gene="engB"
                     /locus_tag="spr1426"
                     /gene_synonym="yihA; ysxC"
                     /note="binds guanine nucleotides; in Escherichia coli
                     depletion results in defective cell division and
                     filamentation; in Bacillus subtilis this gene is
                     essential"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTP-binding protein YsxC"
                     /protein_id="NP_359019.1"
                     /db_xref="GI:15903469"
                     /db_xref="GeneID:933284"
     gene            complement(1411427..1412659)
                     /gene="clpX"
                     /locus_tag="spr1427"
                     /db_xref="GeneID:933131"
     CDS             complement(1411427..1412659)
                     /gene="clpX"
                     /locus_tag="spr1427"
                     /note="binds and unfolds substrates as part of the ClpXP
                     protease"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="NP_359020.1"
                     /db_xref="GI:15903470"
                     /db_xref="GeneID:933131"
     gene            complement(1412691..1412861)
                     /locus_tag="spr1428"
                     /db_xref="GeneID:933094"
     CDS             complement(1412691..1412861)
                     /locus_tag="spr1428"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359021.1"
                     /db_xref="GI:15903471"
                     /db_xref="GeneID:933094"
     gene            complement(1412861..1413367)
                     /gene="dfr"
                     /locus_tag="spr1429"
                     /db_xref="GeneID:933011"
     CDS             complement(1412861..1413367)
                     /gene="dfr"
                     /locus_tag="spr1429"
                     /EC_number="1.5.1.3"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="NP_359022.1"
                     /db_xref="GI:15903472"
                     /db_xref="GeneID:933011"
     gene            complement(1413497..1414033)
                     /gene="dpr"
                     /locus_tag="spr1430"
                     /db_xref="GeneID:933945"
     CDS             complement(1413497..1414033)
                     /gene="dpr"
                     /locus_tag="spr1430"
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme iron-containing ferritin"
                     /protein_id="NP_359023.1"
                     /db_xref="GI:15903473"
                     /db_xref="GeneID:933945"
     repeat_region   complement(1414178..1414286)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1414511..1416016)
                     /gene="lytC"
                     /locus_tag="spr1431"
                     /db_xref="GeneID:933163"
     CDS             complement(1414511..1416016)
                     /gene="lytC"
                     /locus_tag="spr1431"
                     /EC_number="3.2.1.17"
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-beta-N-acetylmuramidase"
                     /protein_id="NP_359024.1"
                     /db_xref="GI:15903474"
                     /db_xref="GeneID:933163"
     gene            complement(1416054..1416833)
                     /gene="tpiA"
                     /locus_tag="spr1432"
                     /db_xref="GeneID:933104"
     CDS             complement(1416054..1416833)
                     /gene="tpiA"
                     /locus_tag="spr1432"
                     /EC_number="5.3.1.1"
                     /note="Reversibly isomerizes the ketone sugar
                     dihydroxyacetone phosphate to the aldehyde sugar
                     glyceraldehyde-3-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="triosephosphate isomerase"
                     /protein_id="NP_359025.1"
                     /db_xref="GI:15903475"
                     /db_xref="GeneID:933104"
     gene            complement(1416910..1417587)
                     /locus_tag="spr1433"
                     /db_xref="GeneID:933431"
     CDS             complement(1416910..1417587)
                     /locus_tag="spr1433"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359026.1"
                     /db_xref="GI:15903476"
                     /db_xref="GeneID:933431"
     gene            complement(1417596..1418540)
                     /gene="metA"
                     /locus_tag="spr1434"
                     /db_xref="GeneID:933387"
     CDS             complement(1417596..1418540)
                     /gene="metA"
                     /locus_tag="spr1434"
                     /EC_number="2.3.1.46"
                     /note="catalyzes the formation of O-succinyl-L-homoserine
                     from succinyl-CoA and L-homoserine in methionine
                     biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="NP_359027.1"
                     /db_xref="GI:15903477"
                     /db_xref="GeneID:933387"
     gene            complement(1418722..1419252)
                     /gene="apt"
                     /locus_tag="spr1435"
                     /db_xref="GeneID:933430"
     CDS             complement(1418722..1419252)
                     /gene="apt"
                     /locus_tag="spr1435"
                     /EC_number="2.4.2.7"
                     /note="catalyzes a salvage reaction resulting in the
                     formation of AMP which is metabolically less costly than a
                     de novo synthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="NP_359028.1"
                     /db_xref="GI:15903478"
                     /db_xref="GeneID:933430"
     gene            complement(1419322..1420080)
                     /locus_tag="spr1436"
                     /db_xref="GeneID:933409"
     CDS             complement(1419322..1420080)
                     /locus_tag="spr1436"
                     /note="Methyltransferase-like protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359029.1"
                     /db_xref="GI:15903479"
                     /db_xref="GeneID:933409"
     repeat_region   complement(1420280..1420432)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1420581..1421711)
                     /gene="msmK"
                     /locus_tag="spr1437"
                     /db_xref="GeneID:933410"
     CDS             complement(1420581..1421711)
                     /gene="msmK"
                     /locus_tag="spr1437"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="NP_359030.1"
                     /db_xref="GI:15903480"
                     /db_xref="GeneID:933410"
     gene            complement(1421994..1422079)
                     /gene="tRNA-Leu1"
                     /locus_tag="sprt10"
                     /db_xref="GeneID:933839"
     tRNA            complement(1421994..1422079)
                     /gene="tRNA-Leu1"
                     /locus_tag="sprt10"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:933839"
     gene            complement(1422161..1422736)
                     /gene="entB"
                     /locus_tag="spr1438"
                     /db_xref="GeneID:933750"
     CDS             complement(1422161..1422736)
                     /gene="entB"
                     /locus_tag="spr1438"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase"
                     /protein_id="NP_359031.1"
                     /db_xref="GI:15903481"
                     /db_xref="GeneID:933750"
     gene            complement(1422736..1423524)
                     /gene="codY"
                     /locus_tag="spr1439"
                     /db_xref="GeneID:933916"
     CDS             complement(1422736..1423524)
                     /gene="codY"
                     /locus_tag="spr1439"
                     /note="CodY; DNA-binding protein that represses the
                     expression of many genes that are induced as cells make
                     the transition from rapid exponential growth to stationary
                     phase (By similarity). It is a GTP-binding protein that
                     senses the intracellular GTP concentration as an indicator
                     of nutritional limitations. At low GTP concentration it no
                     longer binds GTP and stop to act as a transcriptional
                     repressor"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor CodY"
                     /protein_id="NP_359032.1"
                     /db_xref="GI:15903482"
                     /db_xref="GeneID:933916"
     gene            complement(1423788..1425362)
                     /locus_tag="spr1440"
                     /db_xref="GeneID:933241"
     CDS             complement(1423788..1425362)
                     /locus_tag="spr1440"
                     /note="Probable ATP-dependent RNA helicase"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase"
                     /protein_id="NP_359033.1"
                     /db_xref="GI:15903483"
                     /db_xref="GeneID:933241"
     gene            complement(1425561..1426787)
                     /gene="oxlT"
                     /locus_tag="spr1441"
                     /db_xref="GeneID:933237"
     CDS             complement(1425561..1426787)
                     /gene="oxlT"
                     /locus_tag="spr1441"
                     /codon_start=1
                     /transl_table=11
                     /product="oxalate:formate antiporter"
                     /protein_id="NP_359034.1"
                     /db_xref="GI:15903484"
                     /db_xref="GeneID:933237"
     gene            1426977..1428293
                     /gene="merA"
                     /locus_tag="spr1442"
                     /db_xref="GeneID:933259"
     CDS             1426977..1428293
                     /gene="merA"
                     /locus_tag="spr1442"
                     /note="Involved in disulfide oxidoreductase activity and
                     electron transport"
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="NP_359035.1"
                     /db_xref="GI:15903485"
                     /db_xref="GeneID:933259"
     gene            1428392..1429735
                     /locus_tag="spr1443"
                     /db_xref="GeneID:933333"
     CDS             1428392..1429735
                     /locus_tag="spr1443"
                     /note="three-substrate amide ligase belonging tothe
                     mur-ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359036.1"
                     /db_xref="GI:15903486"
                     /db_xref="GeneID:933333"
     gene            1429735..1430517
                     /gene="cobQ"
                     /locus_tag="spr1444"
                     /db_xref="GeneID:933453"
     CDS             1429735..1430517
                     /gene="cobQ"
                     /locus_tag="spr1444"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359037.1"
                     /db_xref="GI:15903487"
                     /db_xref="GeneID:933453"
     gene            1430643..1431725
                     /gene="pepQ"
                     /locus_tag="spr1445"
                     /db_xref="GeneID:933393"
     CDS             1430643..1431725
                     /gene="pepQ"
                     /locus_tag="spr1445"
                     /EC_number="3.4.13.9"
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="NP_359038.1"
                     /db_xref="GI:15903488"
                     /db_xref="GeneID:933393"
     gene            complement(1432048..1432536)
                     /locus_tag="spr1446"
                     /db_xref="GeneID:933278"
     CDS             complement(1432048..1432536)
                     /locus_tag="spr1446"
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="NP_359039.1"
                     /db_xref="GI:15903489"
                     /db_xref="GeneID:933278"
     gene            complement(1432598..1432870)
                     /locus_tag="spr1447"
                     /db_xref="GeneID:933311"
     CDS             complement(1432598..1432870)
                     /locus_tag="spr1447"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359040.1"
                     /db_xref="GI:15903490"
                     /db_xref="GeneID:933311"
     gene            complement(1433096..1433368)
                     /locus_tag="spr1448"
                     /db_xref="GeneID:932992"
     CDS             complement(1433096..1433368)
                     /locus_tag="spr1448"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359041.1"
                     /db_xref="GI:15903491"
                     /db_xref="GeneID:932992"
     repeat_region   complement(1433424..1433541)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1433540..1434001)
                     /locus_tag="spr1449"
                     /db_xref="GeneID:933240"
     CDS             complement(1433540..1434001)
                     /locus_tag="spr1449"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359042.1"
                     /db_xref="GI:15903492"
                     /db_xref="GeneID:933240"
     gene            complement(1433979..1434752)
                     /gene="pdxK"
                     /locus_tag="spr1450"
                     /db_xref="GeneID:933776"
     CDS             complement(1433979..1434752)
                     /gene="pdxK"
                     /locus_tag="spr1450"
                     /EC_number="2.7.4.7"
                     /note="catalyzes the formation of
                     4-amino-2-methyl-5-diphosphomethylpyrimidine"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine kinase"
                     /protein_id="NP_359043.1"
                     /db_xref="GI:15903493"
                     /db_xref="GeneID:933776"
     gene            complement(1434742..1435491)
                     /gene="truA"
                     /locus_tag="spr1451"
                     /gene_synonym="hisT"
                     /db_xref="GeneID:933799"
     CDS             complement(1434742..1435491)
                     /gene="truA"
                     /locus_tag="spr1451"
                     /gene_synonym="hisT"
                     /EC_number="5.4.99.12"
                     /note="mediates pseudouridylation (positions 38, 39, 40)
                     at the tRNA anticodon region which contributes to the
                     structural stability"
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine synthase A"
                     /protein_id="NP_359044.1"
                     /db_xref="GI:15903494"
                     /db_xref="GeneID:933799"
     repeat_region   1435564..1435646
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     repeat_region   complement(1435649..1435720)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            complement(1435804..1436955)
                     /gene="MFS_transporter"
                     /locus_tag="spr1453"
                     /db_xref="GeneID:933474"
     CDS             complement(1435804..1436955)
                     /gene="MFS_transporter"
                     /locus_tag="spr1453"
                     /codon_start=1
                     /transl_table=11
                     /product="major facilitator transporter"
                     /protein_id="NP_359046.1"
                     /db_xref="GI:15903496"
                     /db_xref="GeneID:933474"
     repeat_region   complement(1437081..1437196)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1437195..1437824)
                     /locus_tag="spr1454"
                     /db_xref="GeneID:934038"
     CDS             complement(1437195..1437824)
                     /locus_tag="spr1454"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359047.1"
                     /db_xref="GI:15903497"
                     /db_xref="GeneID:934038"
     gene            complement(1437827..1438165)
                     /gene="phnA"
                     /locus_tag="spr1455"
                     /db_xref="GeneID:933081"
     CDS             complement(1437827..1438165)
                     /gene="phnA"
                     /locus_tag="spr1455"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359048.1"
                     /db_xref="GI:15903498"
                     /db_xref="GeneID:933081"
     gene            complement(1438296..1438967)
                     /gene="cmk"
                     /locus_tag="spr1456"
                     /db_xref="GeneID:933855"
     CDS             complement(1438296..1438967)
                     /gene="cmk"
                     /locus_tag="spr1456"
                     /EC_number="2.7.4.14"
                     /note="Catalyzes the formation of (d)CDP from ATP and
                     (d)CMP"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidylate kinase"
                     /protein_id="NP_359049.1"
                     /db_xref="GI:15903499"
                     /db_xref="GeneID:933855"
     gene            complement(1438976..1439452)
                     /locus_tag="spr1457"
                     /db_xref="GeneID:933097"
     CDS             complement(1438976..1439452)
                     /locus_tag="spr1457"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359050.1"
                     /db_xref="GI:15903500"
                     /db_xref="GeneID:933097"
     gene            1439432..1439710
                     /gene="fer"
                     /locus_tag="spr1458"
                     /db_xref="GeneID:933123"
     CDS             1439432..1439710
                     /gene="fer"
                     /locus_tag="spr1458"
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="NP_359051.1"
                     /db_xref="GI:15903501"
                     /db_xref="GeneID:933123"
     gene            complement(1439772..1440863)
                     /gene="gtrB"
                     /locus_tag="spr1459"
                     /db_xref="GeneID:933830"
     CDS             complement(1439772..1440863)
                     /gene="gtrB"
                     /locus_tag="spr1459"
                     /EC_number="2.4.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosil transferase"
                     /protein_id="NP_359052.1"
                     /db_xref="GI:15903502"
                     /db_xref="GeneID:933830"
     gene            complement(1440727..1441746)
                     /gene="galE"
                     /locus_tag="spr1460"
                     /db_xref="GeneID:933804"
     CDS             complement(1440727..1441746)
                     /gene="galE"
                     /locus_tag="spr1460"
                     /EC_number="5.1.3.2"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="NP_359053.1"
                     /db_xref="GI:15903503"
                     /db_xref="GeneID:933804"
     repeat_region   1441850..1442046
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1442047..1443159)
                     /locus_tag="spr1461"
                     /db_xref="GeneID:934040"
     CDS             complement(1442047..1443159)
                     /locus_tag="spr1461"
                     /note="Probable oxidase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359054.1"
                     /db_xref="GI:15903504"
                     /db_xref="GeneID:934040"
     gene            complement(1443167..1443964)
                     /locus_tag="spr1462"
                     /db_xref="GeneID:933251"
     CDS             complement(1443167..1443964)
                     /locus_tag="spr1462"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359055.1"
                     /db_xref="GI:15903505"
                     /db_xref="GeneID:933251"
     gene            complement(1443951..1444628)
                     /locus_tag="spr1463"
                     /db_xref="GeneID:933452"
     CDS             complement(1443951..1444628)
                     /locus_tag="spr1463"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359056.1"
                     /db_xref="GI:15903506"
                     /db_xref="GeneID:933452"
     gene            complement(1444730..1447066)
                     /gene="ctpE"
                     /locus_tag="spr1464"
                     /db_xref="GeneID:934036"
     CDS             complement(1444730..1447066)
                     /gene="ctpE"
                     /locus_tag="spr1464"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="metal cation transporter P-type ATPase"
                     /protein_id="NP_359057.1"
                     /db_xref="GI:15903507"
                     /db_xref="GeneID:934036"
     gene            1447154..1447948
                     /locus_tag="spr1465"
                     /db_xref="GeneID:933161"
     CDS             1447154..1447948
                     /locus_tag="spr1465"
                     /note="Probable member of acyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359058.1"
                     /db_xref="GI:15903508"
                     /db_xref="GeneID:933161"
     repeat_region   1447996..1448095
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1448241..1448855)
                     /gene="cadD"
                     /locus_tag="spr1466"
                     /db_xref="GeneID:933449"
     CDS             complement(1448241..1448855)
                     /gene="cadD"
                     /locus_tag="spr1466"
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium resistance protein"
                     /protein_id="NP_359059.1"
                     /db_xref="GI:15903509"
                     /db_xref="GeneID:933449"
     gene            complement(1449589..1449858)
                     /gene="rpsO"
                     /locus_tag="spr1467"
                     /db_xref="GeneID:934037"
     CDS             complement(1449589..1449858)
                     /gene="rpsO"
                     /locus_tag="spr1467"
                     /note="primary rRNA binding protein; helps nucleate
                     assembly of 30S; binds directly to the 16S rRNA and an
                     intersubunit bridge to the 23S rRNA; autoregulates
                     translation through interactions with the mRNA leader
                     sequence"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="NP_359060.1"
                     /db_xref="GI:15903510"
                     /db_xref="GeneID:934037"
     gene            complement(1449999..1450628)
                     /locus_tag="spr1468"
                     /db_xref="GeneID:932978"
     CDS             complement(1449999..1450628)
                     /locus_tag="spr1468"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359061.1"
                     /db_xref="GI:15903511"
                     /db_xref="GeneID:932978"
     gene            1451498..1451821
                     /locus_tag="spr1470"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933001"
     gene            1451879..1453822
                     /gene="thrS"
                     /locus_tag="spr1472"
                     /db_xref="GeneID:934039"
     CDS             1451879..1453822
                     /gene="thrS"
                     /locus_tag="spr1472"
                     /EC_number="6.1.1.3"
                     /note="catalyzes a two-step reaction, first charging a
                     threonine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; catalyzes the formation
                     of threonyl-tRNA(Thr) from threonine and tRNA(Thr)"
                     /codon_start=1
                     /transl_table=11
                     /product="threonyl-tRNA synthetase"
                     /protein_id="NP_359065.2"
                     /db_xref="GI:161410743"
                     /db_xref="GeneID:934039"
     gene            complement(1453871..1454845)
                     /gene="hk01"
                     /locus_tag="spr1473"
                     /db_xref="GeneID:933107"
     CDS             complement(1453871..1454845)
                     /gene="hk01"
                     /locus_tag="spr1473"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="NP_359066.1"
                     /db_xref="GI:15903516"
                     /db_xref="GeneID:933107"
     gene            complement(1454838..1455515)
                     /gene="rr01"
                     /locus_tag="spr1474"
                     /db_xref="GeneID:933349"
     CDS             complement(1454838..1455515)
                     /gene="rr01"
                     /locus_tag="spr1474"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_359067.1"
                     /db_xref="GI:15903517"
                     /db_xref="GeneID:933349"
     gene            1455671..1456744
                     /locus_tag="spr1475"
                     /db_xref="GeneID:933114"
     CDS             1455671..1456744
                     /locus_tag="spr1475"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359068.1"
                     /db_xref="GI:15903518"
                     /db_xref="GeneID:933114"
     gene            complement(1456835..1457137)
                     /locus_tag="spr1476"
                     /db_xref="GeneID:933100"
     CDS             complement(1456835..1457137)
                     /locus_tag="spr1476"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359069.1"
                     /db_xref="GI:15903519"
                     /db_xref="GeneID:933100"
     gene            complement(1457206..1457643)
                     /locus_tag="spr1477"
                     /db_xref="GeneID:934035"
     CDS             complement(1457206..1457643)
                     /locus_tag="spr1477"
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family protein"
                     /protein_id="NP_359070.1"
                     /db_xref="GI:15903520"
                     /db_xref="GeneID:934035"
     gene            complement(1457719..1458567)
                     /locus_tag="spr1479"
                     /db_xref="GeneID:933056"
     CDS             complement(1457719..1458567)
                     /locus_tag="spr1479"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359072.1"
                     /db_xref="GI:15903522"
                     /db_xref="GeneID:933056"
     gene            1458673..1459323
                     /gene="marR"
                     /locus_tag="spr1480"
                     /db_xref="GeneID:933026"
     CDS             1458673..1459323
                     /gene="marR"
                     /locus_tag="spr1480"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent transcriptional regulator"
                     /protein_id="NP_359073.1"
                     /db_xref="GI:15903523"
                     /db_xref="GeneID:933026"
     gene            1459304..1459474
                     /locus_tag="spr1481"
                     /db_xref="GeneID:933112"
     CDS             1459304..1459474
                     /locus_tag="spr1481"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359074.1"
                     /db_xref="GI:15903524"
                     /db_xref="GeneID:933112"
     gene            1459625..1460145
                     /locus_tag="spr1482"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933151"
     gene            1460276..1460713
                     /locus_tag="spr1483"
                     /db_xref="GeneID:933051"
     CDS             1460276..1460713
                     /locus_tag="spr1483"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359076.1"
                     /db_xref="GI:15903526"
                     /db_xref="GeneID:933051"
     gene            complement(1460808..1461107)
                     /locus_tag="spr1484"
                     /db_xref="GeneID:933074"
     CDS             complement(1460808..1461107)
                     /locus_tag="spr1484"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359077.1"
                     /db_xref="GI:15903527"
                     /db_xref="GeneID:933074"
     gene            1462009..1462423
                     /locus_tag="spr1485"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933111"
     gene            complement(1462462..1462905)
                     /locus_tag="spr1486"
                     /db_xref="GeneID:933118"
     CDS             complement(1462462..1462905)
                     /locus_tag="spr1486"
                     /note="hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and
                     free tRNA(Tyr); possible defense mechanism against a
                     harmful effect of D-tyrosine"
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="NP_359079.1"
                     /db_xref="GI:15903529"
                     /db_xref="GeneID:933118"
     gene            complement(1462935..1465157)
                     /gene="relA"
                     /locus_tag="spr1487"
                     /db_xref="GeneID:933127"
     CDS             complement(1462935..1465157)
                     /gene="relA"
                     /locus_tag="spr1487"
                     /EC_number="2.7.6.5"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="NP_359080.1"
                     /db_xref="GI:15903530"
                     /db_xref="GeneID:933127"
     repeat_region   complement(1465450..1465599)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     repeat_region   complement(1466008..1466124)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            1466101..1466781
                     /locus_tag="spr1490"
                     /db_xref="GeneID:933105"
     CDS             1466101..1466781
                     /locus_tag="spr1490"
                     /note="Probable member of metallo-beta-lactamase
                     superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="metallo-beta-lactamase superfamily protein"
                     /protein_id="NP_359083.1"
                     /db_xref="GI:15903533"
                     /db_xref="GeneID:933105"
     gene            complement(1466904..1468796)
                     /gene="pepO"
                     /locus_tag="spr1491"
                     /db_xref="GeneID:933477"
     CDS             complement(1466904..1468796)
                     /gene="pepO"
                     /locus_tag="spr1491"
                     /EC_number="3.4.24.-"
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase O"
                     /protein_id="NP_359084.1"
                     /db_xref="GI:15903534"
                     /db_xref="GeneID:933477"
     gene            1469087..1469809
                     /gene="psaB"
                     /locus_tag="spr1492"
                     /db_xref="GeneID:933772"
     CDS             1469087..1469809
                     /gene="psaB"
                     /locus_tag="spr1492"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese ABC transporter ATP-binding protein"
                     /protein_id="NP_359085.1"
                     /db_xref="GI:15903535"
                     /db_xref="GeneID:933772"
     gene            1469806..1470654
                     /gene="psaC"
                     /locus_tag="spr1493"
                     /db_xref="GeneID:933751"
     CDS             1469806..1470654
                     /gene="psaC"
                     /locus_tag="spr1493"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese ABC transporter permease"
                     /protein_id="NP_359086.1"
                     /db_xref="GI:15903536"
                     /db_xref="GeneID:933751"
     gene            1470686..1471615
                     /gene="psaA"
                     /locus_tag="spr1494"
                     /db_xref="GeneID:933003"
     CDS             1470686..1471615
                     /gene="psaA"
                     /locus_tag="spr1494"
                     /codon_start=1
                     /transl_table=11
                     /product="manganese ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_359087.1"
                     /db_xref="GI:15903537"
                     /db_xref="GeneID:933003"
     gene            1471738..1472229
                     /gene="tpx"
                     /locus_tag="spr1495"
                     /db_xref="GeneID:933932"
     CDS             1471738..1472229
                     /gene="tpx"
                     /locus_tag="spr1495"
                     /EC_number="1.11.1.-"
                     /note="antioxidant activity; thioredoxin-dependent thiol
                     peroxidase; forms homodimers in solution; shows substrate
                     specificity to alkyl hydroperoxides; periplasmic protein"
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="NP_359088.2"
                     /db_xref="GI:161410742"
                     /db_xref="GeneID:933932"
     gene            complement(1472325..1475099)
                     /locus_tag="spr1496"
                     /db_xref="GeneID:933117"
     CDS             complement(1472325..1475099)
                     /locus_tag="spr1496"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359089.1"
                     /db_xref="GI:15903539"
                     /db_xref="GeneID:933117"
     gene            complement(1475035..1475745)
                     /gene="ABC-NBD"
                     /locus_tag="spr1497"
                     /db_xref="GeneID:933758"
     CDS             complement(1475035..1475745)
                     /gene="ABC-NBD"
                     /locus_tag="spr1497"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359090.1"
                     /db_xref="GI:15903540"
                     /db_xref="GeneID:933758"
     repeat_region   1475762..1475879
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1475986..1478397)
                     /locus_tag="spr1498"
                     /db_xref="GeneID:933748"
     CDS             complement(1475986..1478397)
                     /locus_tag="spr1498"
                     /note="large secreted protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359091.1"
                     /db_xref="GI:15903541"
                     /db_xref="GeneID:933748"
     gene            complement(1478450..1479142)
                     /gene="gpmA"
                     /locus_tag="spr1499"
                     /db_xref="GeneID:933138"
     CDS             complement(1478450..1479142)
                     /gene="gpmA"
                     /locus_tag="spr1499"
                     /EC_number="5.4.2.1"
                     /note="2,3-bisphosphoglycerate-dependent; catalyzes the
                     interconversion of 2-phosphoglycerate to
                     3-phosphoglycerate"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglyceromutase"
                     /protein_id="NP_359092.1"
                     /db_xref="GI:15903542"
                     /db_xref="GeneID:933138"
     gene            complement(1479193..1479381)
                     /locus_tag="spr1500"
                     /db_xref="GeneID:933817"
     CDS             complement(1479193..1479381)
                     /locus_tag="spr1500"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359093.1"
                     /db_xref="GI:15903543"
                     /db_xref="GeneID:933817"
     gene            complement(1479677..1480017)
                     /locus_tag="spr1501"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933837"
     gene            complement(1480465..1483257)
                     /gene="ileS"
                     /locus_tag="spr1502"
                     /db_xref="GeneID:933475"
     CDS             complement(1480465..1483257)
                     /gene="ileS"
                     /locus_tag="spr1502"
                     /EC_number="6.1.1.5"
                     /note="IleRS; catalyzes the formation of
                     isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since
                     isoleucine and other amino acids such as valine are
                     similar, there are additional editing function in this
                     enzyme; one is involved in hydrolysis of activated
                     valine-AMP and the other is involved in deacylation of
                     mischarged Val-tRNA(Ile); there are two active sites, one
                     for aminoacylation and one for editing; class-I
                     aminoacyl-tRNA synthetase type 1 subfamily; some organisms
                     carry two different copies of this enzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucyl-tRNA synthetase"
                     /protein_id="NP_359095.1"
                     /db_xref="GI:15903545"
                     /db_xref="GeneID:933475"
     gene            complement(1483401..1483562)
                     /locus_tag="spr1503"
                     /db_xref="GeneID:933024"
     CDS             complement(1483401..1483562)
                     /locus_tag="spr1503"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359096.1"
                     /db_xref="GI:15903546"
                     /db_xref="GeneID:933024"
     gene            complement(1483605..1484405)
                     /gene="divIVA"
                     /locus_tag="spr1505"
                     /db_xref="GeneID:933446"
     CDS             complement(1483605..1484405)
                     /gene="divIVA"
                     /locus_tag="spr1505"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="NP_359098.1"
                     /db_xref="GI:15903548"
                     /db_xref="GeneID:933446"
     gene            complement(1484402..1485253)
                     /locus_tag="spr1506"
                     /db_xref="GeneID:933236"
     CDS             complement(1484402..1485253)
                     /locus_tag="spr1506"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359099.1"
                     /db_xref="GI:15903549"
                     /db_xref="GeneID:933236"
     gene            complement(1485184..1485447)
                     /locus_tag="spr1507"
                     /db_xref="GeneID:934045"
     CDS             complement(1485184..1485447)
                     /locus_tag="spr1507"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359100.1"
                     /db_xref="GI:15903550"
                     /db_xref="GeneID:934045"
     gene            complement(1485447..1485986)
                     /locus_tag="spr1508"
                     /db_xref="GeneID:933746"
     CDS             complement(1485447..1485986)
                     /locus_tag="spr1508"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359101.1"
                     /db_xref="GI:15903551"
                     /db_xref="GeneID:933746"
     gene            complement(1485996..1486667)
                     /locus_tag="spr1509"
                     /db_xref="GeneID:933484"
     CDS             complement(1485996..1486667)
                     /locus_tag="spr1509"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359102.1"
                     /db_xref="GI:15903552"
                     /db_xref="GeneID:933484"
     gene            complement(1486672..1487931)
                     /gene="ftsZ"
                     /locus_tag="spr1510"
                     /db_xref="GeneID:933826"
     CDS             complement(1486672..1487931)
                     /gene="ftsZ"
                     /locus_tag="spr1510"
                     /note="GTPase; similar structure to tubulin; forms
                     ring-shaped polymers at the site of cell division; other
                     proteins such as FtsA, ZipA, and ZapA, interact with and
                     regulate FtsZ function"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="NP_359103.1"
                     /db_xref="GI:15903553"
                     /db_xref="GeneID:933826"
     gene            complement(1487948..1489321)
                     /gene="ftsA"
                     /locus_tag="spr1511"
                     /db_xref="GeneID:933392"
     CDS             complement(1487948..1489321)
                     /gene="ftsA"
                     /locus_tag="spr1511"
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="NP_359104.1"
                     /db_xref="GI:15903554"
                     /db_xref="GeneID:933392"
     gene            complement(1489540..1490244)
                     /locus_tag="spr1512"
                     /db_xref="GeneID:933008"
     CDS             complement(1489540..1490244)
                     /locus_tag="spr1512"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359105.1"
                     /db_xref="GI:15903555"
                     /db_xref="GeneID:933008"
     gene            complement(1490335..1490946)
                     /gene="mutT"
                     /locus_tag="spr1513"
                     /db_xref="GeneID:933010"
     CDS             complement(1490335..1490946)
                     /gene="mutT"
                     /locus_tag="spr1513"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="NP_359106.1"
                     /db_xref="GI:15903556"
                     /db_xref="GeneID:933010"
     gene            complement(1490933..1492306)
                     /gene="murF"
                     /locus_tag="spr1514"
                     /db_xref="GeneID:933049"
     CDS             complement(1490933..1492306)
                     /gene="murF"
                     /locus_tag="spr1514"
                     /EC_number="6.3.2.10"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanine-D-glutamyl-lysine-D-
                     alanyl-D-alanine ligase"
                     /protein_id="NP_359107.1"
                     /db_xref="GI:15903557"
                     /db_xref="GeneID:933049"
     gene            complement(1492390..1493433)
                     /gene="ddl"
                     /locus_tag="spr1515"
                     /db_xref="GeneID:933362"
     CDS             complement(1492390..1493433)
                     /gene="ddl"
                     /locus_tag="spr1515"
                     /EC_number="6.3.2.4"
                     /note="D-alanine--D-alanine ligase; DdlA; DdlB;
                     cytoplasmic; catalyzes the formation of D-alanyl-D-alanine
                     from two D-alanines in peptidoglycan synthesis; there are
                     two forms of this enzyme in Escherichia coli"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-alanine synthetase A"
                     /protein_id="NP_359108.1"
                     /db_xref="GI:15903558"
                     /db_xref="GeneID:933362"
     gene            complement(1493609..1494205)
                     /gene="recR"
                     /locus_tag="spr1516"
                     /db_xref="GeneID:933153"
     CDS             complement(1493609..1494205)
                     /gene="recR"
                     /locus_tag="spr1516"
                     /note="involved in a recombinational process of DNA
                     repair, independent of the recBC complex"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="NP_359109.1"
                     /db_xref="GI:15903559"
                     /db_xref="GeneID:933153"
     gene            complement(1494216..1496273)
                     /gene="pbp2b"
                     /locus_tag="spr1517"
                     /db_xref="GeneID:933948"
     CDS             complement(1494216..1496273)
                     /gene="pbp2b"
                     /locus_tag="spr1517"
                     /EC_number="2.3.2.-"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="NP_359110.1"
                     /db_xref="GI:15903560"
                     /db_xref="GeneID:933948"
     gene            1496473..1497324
                     /locus_tag="spr1518"
                     /db_xref="GeneID:933935"
     CDS             1496473..1497324
                     /locus_tag="spr1518"
                     /note="Probable transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphosugar-binding transcriptional regulator"
                     /protein_id="NP_359111.1"
                     /db_xref="GI:15903561"
                     /db_xref="GeneID:933935"
     gene            complement(1497340..1498224)
                     /gene="glk"
                     /locus_tag="spr1519"
                     /db_xref="GeneID:933382"
     CDS             complement(1497340..1498224)
                     /gene="glk"
                     /locus_tag="spr1519"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="NP_359112.1"
                     /db_xref="GI:15903562"
                     /db_xref="GeneID:933382"
     gene            complement(1499342..1499806)
                     /locus_tag="spr1522"
                     /db_xref="GeneID:933394"
     CDS             complement(1499342..1499806)
                     /locus_tag="spr1522"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359115.1"
                     /db_xref="GI:15903565"
                     /db_xref="GeneID:933394"
     gene            complement(1500093..1500437)
                     /locus_tag="spr1523"
                     /db_xref="GeneID:933062"
     CDS             complement(1500093..1500437)
                     /locus_tag="spr1523"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359116.1"
                     /db_xref="GI:15903566"
                     /db_xref="GeneID:933062"
     gene            complement(1500534..1500986)
                     /locus_tag="spr1524"
                     /db_xref="GeneID:933054"
     CDS             complement(1500534..1500986)
                     /locus_tag="spr1524"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359117.1"
                     /db_xref="GI:15903567"
                     /db_xref="GeneID:933054"
     gene            complement(1501259..1502098)
                     /gene="ABC-MSP"
                     /locus_tag="spr1525"
                     /db_xref="GeneID:933433"
     CDS             complement(1501259..1502098)
                     /gene="ABC-MSP"
                     /locus_tag="spr1525"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359118.1"
                     /db_xref="GI:15903568"
                     /db_xref="GeneID:933433"
     gene            complement(1502114..1503010)
                     /gene="ABC-MSP"
                     /locus_tag="spr1526"
                     /db_xref="GeneID:933757"
     CDS             complement(1502114..1503010)
                     /gene="ABC-MSP"
                     /locus_tag="spr1526"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359119.1"
                     /db_xref="GI:15903569"
                     /db_xref="GeneID:933757"
     gene            complement(1503232..1504560)
                     /gene="ABC-SBP"
                     /locus_tag="spr1527"
                     /db_xref="GeneID:933832"
     CDS             complement(1503232..1504560)
                     /gene="ABC-SBP"
                     /locus_tag="spr1527"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="NP_359120.1"
                     /db_xref="GI:15903570"
                     /db_xref="GeneID:933832"
     gene            complement(1504685..1506217)
                     /gene="PTS-EII"
                     /locus_tag="spr1528"
                     /db_xref="GeneID:933910"
     CDS             complement(1504685..1506217)
                     /gene="PTS-EII"
                     /locus_tag="spr1528"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIBC"
                     /protein_id="NP_359121.1"
                     /db_xref="GI:15903571"
                     /db_xref="GeneID:933910"
     gene            complement(1506221..1506919)
                     /gene="nanE"
                     /locus_tag="spr1529"
                     /db_xref="GeneID:933779"
     CDS             complement(1506221..1506919)
                     /gene="nanE"
                     /locus_tag="spr1529"
                     /EC_number="5.1.3.9"
                     /note="Converts N-acetylmannosamine-6-phosphate to
                     N-acetylglucosamine-6-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="NP_359122.1"
                     /db_xref="GI:15903572"
                     /db_xref="GeneID:933779"
     gene            complement(1507099..1508202)
                     /locus_tag="spr1530"
                     /db_xref="GeneID:933464"
     CDS             complement(1507099..1508202)
                     /locus_tag="spr1530"
                     /note="Probable Oxidoreductase, GFO/IDH/MOCA family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359123.1"
                     /db_xref="GI:15903573"
                     /db_xref="GeneID:933464"
     gene            complement(1508214..1510307)
                     /gene="nanB"
                     /locus_tag="spr1531"
                     /db_xref="GeneID:933504"
     CDS             complement(1508214..1510307)
                     /gene="nanB"
                     /locus_tag="spr1531"
                     /EC_number="3.2.1.18"
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase B"
                     /protein_id="NP_359124.1"
                     /db_xref="GI:15903574"
                     /db_xref="GeneID:933504"
     gene            complement(1510325..1511158)
                     /gene="ABC-MSP"
                     /locus_tag="spr1532"
                     /db_xref="GeneID:933445"
     CDS             complement(1510325..1511158)
                     /gene="ABC-MSP"
                     /locus_tag="spr1532"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359125.1"
                     /db_xref="GI:15903575"
                     /db_xref="GeneID:933445"
     gene            complement(1511158..1512042)
                     /gene="ABC-MSP"
                     /locus_tag="spr1533"
                     /db_xref="GeneID:932934"
     CDS             complement(1511158..1512042)
                     /gene="ABC-MSP"
                     /locus_tag="spr1533"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359126.1"
                     /db_xref="GI:15903576"
                     /db_xref="GeneID:932934"
     gene            complement(1512121..1513458)
                     /gene="ABC-SBP"
                     /locus_tag="spr1534"
                     /db_xref="GeneID:933015"
     CDS             complement(1512121..1513458)
                     /gene="ABC-SBP"
                     /locus_tag="spr1534"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="NP_359127.1"
                     /db_xref="GI:15903577"
                     /db_xref="GeneID:933015"
     gene            complement(1513477..1513929)
                     /locus_tag="spr1535"
                     /db_xref="GeneID:933295"
     CDS             complement(1513477..1513929)
                     /locus_tag="spr1535"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359128.1"
                     /db_xref="GI:15903578"
                     /db_xref="GeneID:933295"
     repeat_region   1514032..1514169
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     repeat_region   1514699..1514798
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            complement(1514944..1518051)
                     /gene="nanA"
                     /locus_tag="spr1536"
                     /db_xref="GeneID:933902"
     CDS             complement(1514944..1518051)
                     /gene="nanA"
                     /locus_tag="spr1536"
                     /EC_number="3.2.1.18"
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase A"
                     /protein_id="NP_359129.1"
                     /db_xref="GI:15903579"
                     /db_xref="GeneID:933902"
     gene            complement(1518294..1518521)
                     /locus_tag="spr1537"
                     /db_xref="GeneID:933895"
     CDS             complement(1518294..1518521)
                     /locus_tag="spr1537"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359130.1"
                     /db_xref="GI:15903580"
                     /db_xref="GeneID:933895"
     repeat_region   complement(1518804..1519080)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbbbba"
     repeat_region   1519214..1519320
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1519416..1520396)
                     /gene="axe1"
                     /locus_tag="spr1538"
                     /db_xref="GeneID:933372"
     CDS             complement(1519416..1520396)
                     /gene="axe1"
                     /locus_tag="spr1538"
                     /EC_number="3.1.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl xylan esterase"
                     /protein_id="NP_359131.1"
                     /db_xref="GI:15903581"
                     /db_xref="GeneID:933372"
     gene            complement(1520712..1522727)
                     /gene="recG"
                     /locus_tag="spr1539"
                     /db_xref="GeneID:933472"
     CDS             complement(1520712..1522727)
                     /gene="recG"
                     /locus_tag="spr1539"
                     /EC_number="3.6.1.-"
                     /note="catalyzes branch migration in Holliday junction
                     intermediates"
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="NP_359132.1"
                     /db_xref="GI:15903582"
                     /db_xref="GeneID:933472"
     gene            complement(1522746..1523870)
                     /gene="alr"
                     /locus_tag="spr1540"
                     /db_xref="GeneID:933368"
     CDS             complement(1522746..1523870)
                     /gene="alr"
                     /locus_tag="spr1540"
                     /EC_number="5.1.1.1"
                     /note="converts L-alanine to D-alanine which is used in
                     cell wall biosynthesis; binds one pyridoxal phosphate per
                     monomer; forms a homodimer"
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="NP_359133.1"
                     /db_xref="GI:15903583"
                     /db_xref="GeneID:933368"
     gene            complement(1523839..1524201)
                     /gene="acpS"
                     /locus_tag="spr1541"
                     /db_xref="GeneID:933057"
     CDS             complement(1523839..1524201)
                     /gene="acpS"
                     /locus_tag="spr1541"
                     /EC_number="2.7.8.7"
                     /note="Catalyzes the formation of holo-ACP, which mediates
                     the essential transfer of acyl fatty acid intermediates
                     during the biosynthesis of fatty acids and lipids"
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="NP_359134.1"
                     /db_xref="GI:15903584"
                     /db_xref="GeneID:933057"
     gene            complement(1524246..1525277)
                     /gene="aroF"
                     /locus_tag="spr1542"
                     /db_xref="GeneID:932815"
     CDS             complement(1524246..1525277)
                     /gene="aroF"
                     /locus_tag="spr1542"
                     /EC_number="2.5.1.54"
                     /note="catalyzes the formation of
                     3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from
                     phosphoenolpyruvate and D-erythrose 4-phosphate,
                     phenylalanine sensitive"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /protein_id="NP_359135.1"
                     /db_xref="GI:15903585"
                     /db_xref="GeneID:932815"
     gene            complement(1525279..1526310)
                     /gene="aroG"
                     /locus_tag="spr1543"
                     /db_xref="GeneID:933155"
     CDS             complement(1525279..1526310)
                     /gene="aroG"
                     /locus_tag="spr1543"
                     /EC_number="2.5.1.54"
                     /note="catalyzes the formation of
                     3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from
                     phosphoenolpyruvate and D-erythrose 4-phosphate, tyrosine
                     sensitive"
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-2-dehydro-3-deoxyheptonate aldolase"
                     /protein_id="NP_359136.1"
                     /db_xref="GI:15903586"
                     /db_xref="GeneID:933155"
     gene            complement(1526391..1528904)
                     /gene="secA"
                     /locus_tag="spr1544"
                     /gene_synonym="azi; div"
                     /db_xref="GeneID:933782"
     CDS             complement(1526391..1528904)
                     /gene="secA"
                     /locus_tag="spr1544"
                     /gene_synonym="azi; div"
                     /note="functions in protein export; can interact with
                     acidic membrane phospholipids and the SecYEG protein
                     complex; binds to preproteins; binds to ATP and undergoes
                     a conformational change to promote membrane insertion of
                     SecA/bound preprotein; ATP hydrolysis appears to drive
                     release of the preprotein from SecA and deinsertion of
                     SecA from the membrane; additional proteins SecD/F/YajC
                     aid SecA recycling; exists in an equilibrium between
                     monomers and dimers; may possibly form higher order
                     oligomers; proteins in this cluster correspond SecA1;
                     SecA2 is not essential and seems to play a role in
                     secretion of a subset of proteins"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="NP_359137.1"
                     /db_xref="GI:15903587"
                     /db_xref="GeneID:933782"
     gene            complement(1529050..1529250)
                     /locus_tag="spr1545"
                     /db_xref="GeneID:933079"
     CDS             complement(1529050..1529250)
                     /locus_tag="spr1545"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359138.1"
                     /db_xref="GI:15903588"
                     /db_xref="GeneID:933079"
     gene            complement(1529350..1530000)
                     /gene="ABC-NBD"
                     /locus_tag="spr1546"
                     /db_xref="GeneID:933956"
     CDS             complement(1529350..1530000)
                     /gene="ABC-NBD"
                     /locus_tag="spr1546"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359139.1"
                     /db_xref="GI:15903589"
                     /db_xref="GeneID:933956"
     gene            complement(1530004..1530681)
                     /locus_tag="spr1547"
                     /db_xref="GeneID:933752"
     CDS             complement(1530004..1530681)
                     /locus_tag="spr1547"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359140.1"
                     /db_xref="GI:15903590"
                     /db_xref="GeneID:933752"
     gene            complement(1530638..1531429)
                     /locus_tag="spr1548"
                     /db_xref="GeneID:933749"
     CDS             complement(1530638..1531429)
                     /locus_tag="spr1548"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359141.1"
                     /db_xref="GI:15903591"
                     /db_xref="GeneID:933749"
     gene            complement(1531451..1531843)
                     /locus_tag="spr1549"
                     /db_xref="GeneID:933033"
     CDS             complement(1531451..1531843)
                     /locus_tag="spr1549"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359142.1"
                     /db_xref="GI:15903592"
                     /db_xref="GeneID:933033"
     gene            1532170..1533021
                     /locus_tag="spr1550"
                     /db_xref="GeneID:933229"
     CDS             1532170..1533021
                     /locus_tag="spr1550"
                     /note="Similar to MutR protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359143.1"
                     /db_xref="GI:15903593"
                     /db_xref="GeneID:933229"
     gene            complement(1533243..1533596)
                     /locus_tag="spr1551"
                     /db_xref="GeneID:933020"
     CDS             complement(1533243..1533596)
                     /locus_tag="spr1551"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359144.1"
                     /db_xref="GI:15903594"
                     /db_xref="GeneID:933020"
     gene            complement(1533733..1534077)
                     /locus_tag="spr1552"
                     /db_xref="GeneID:932941"
     CDS             complement(1533733..1534077)
                     /locus_tag="spr1552"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359145.1"
                     /db_xref="GI:15903595"
                     /db_xref="GeneID:932941"
     gene            complement(1534157..1535467)
                     /gene="engA"
                     /locus_tag="spr1553"
                     /gene_synonym="yfgK; yphC"
                     /db_xref="GeneID:933135"
     CDS             complement(1534157..1535467)
                     /gene="engA"
                     /locus_tag="spr1553"
                     /gene_synonym="yfgK; yphC"
                     /note="EngA; essential Neisserial GTPase; synchronizes
                     cellular events by interacting with multiple targets with
                     tandem G-domains; overexpression in Escherichia coli
                     suppresses rrmJ mutation; structural analysis of the
                     Thermotoga maritima ortholog shows different nucleotide
                     binding affinities in the two binding domains"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein EngA"
                     /protein_id="NP_359146.1"
                     /db_xref="GI:15903596"
                     /db_xref="GeneID:933135"
     gene            complement(1535481..1536194)
                     /gene="frp"
                     /locus_tag="spr1554"
                     /db_xref="GeneID:933420"
     CDS             complement(1535481..1536194)
                     /gene="frp"
                     /locus_tag="spr1554"
                     /EC_number="1.6.99.-"
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase"
                     /protein_id="NP_359147.1"
                     /db_xref="GI:15903597"
                     /db_xref="GeneID:933420"
     gene            complement(1536191..1537087)
                     /gene="dnaI"
                     /locus_tag="spr1555"
                     /db_xref="GeneID:933865"
     CDS             complement(1536191..1537087)
                     /gene="dnaI"
                     /locus_tag="spr1555"
                     /note="Primosomal protein that may act to load helicase
                     DnaC during DNA replication"
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="NP_359148.1"
                     /db_xref="GI:15903598"
                     /db_xref="GeneID:933865"
     gene            complement(1537088..1538257)
                     /gene="dnaB"
                     /locus_tag="spr1556"
                     /db_xref="GeneID:933424"
     CDS             complement(1537088..1538257)
                     /gene="dnaB"
                     /locus_tag="spr1556"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359149.1"
                     /db_xref="GI:15903599"
                     /db_xref="GeneID:933424"
     gene            complement(1538258..1538731)
                     /gene="nrdR"
                     /locus_tag="spr1557"
                     /db_xref="GeneID:933896"
     CDS             complement(1538258..1538731)
                     /gene="nrdR"
                     /locus_tag="spr1557"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="NP_359150.2"
                     /db_xref="GI:161410741"
                     /db_xref="GeneID:933896"
     gene            1538871..1539236
                     /locus_tag="spr1558"
                     /db_xref="GeneID:933463"
     CDS             1538871..1539236
                     /locus_tag="spr1558"
                     /note="Similar to transcriptional regulator (GntR family)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359151.1"
                     /db_xref="GI:15903601"
                     /db_xref="GeneID:933463"
     gene            1539214..1539936
                     /gene="ABC-NBD"
                     /locus_tag="spr1559"
                     /db_xref="GeneID:933133"
     CDS             1539214..1539936
                     /gene="ABC-NBD"
                     /locus_tag="spr1559"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359152.1"
                     /db_xref="GI:15903602"
                     /db_xref="GeneID:933133"
     gene            1539872..1540720
                     /locus_tag="spr1560"
                     /db_xref="GeneID:933149"
     CDS             1539872..1540720
                     /locus_tag="spr1560"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359153.1"
                     /db_xref="GI:15903603"
                     /db_xref="GeneID:933149"
     gene            complement(1541133..1542332)
                     /gene="natB"
                     /locus_tag="spr1561"
                     /db_xref="GeneID:933936"
     CDS             complement(1541133..1542332)
                     /gene="natB"
                     /locus_tag="spr1561"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359154.1"
                     /db_xref="GI:15903604"
                     /db_xref="GeneID:933936"
     gene            complement(1542329..1543222)
                     /gene="natA"
                     /locus_tag="spr1562"
                     /db_xref="GeneID:933125"
     CDS             complement(1542329..1543222)
                     /gene="natA"
                     /locus_tag="spr1562"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359155.1"
                     /db_xref="GI:15903605"
                     /db_xref="GeneID:933125"
     repeat_region   complement(1543334..1543533)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     repeat_region   complement(1543799..1543905)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            1544531..1545148
                     /locus_tag="spr1564"
                     /db_xref="GeneID:933073"
     CDS             1544531..1545148
                     /locus_tag="spr1564"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359157.1"
                     /db_xref="GI:15903607"
                     /db_xref="GeneID:933073"
     gene            complement(1545468..1546355)
                     /gene="scrK"
                     /locus_tag="spr1565"
                     /db_xref="GeneID:933152"
     CDS             complement(1545468..1546355)
                     /gene="scrK"
                     /locus_tag="spr1565"
                     /EC_number="2.7.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="NP_359158.1"
                     /db_xref="GI:15903608"
                     /db_xref="GeneID:933152"
     gene            complement(1546504..1548387)
                     /gene="scrA"
                     /locus_tag="spr1566"
                     /db_xref="GeneID:933361"
     CDS             complement(1546504..1548387)
                     /gene="scrA"
                     /locus_tag="spr1566"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIABC"
                     /protein_id="NP_359159.1"
                     /db_xref="GI:15903609"
                     /db_xref="GeneID:933361"
     gene            1548764..1550218
                     /gene="scrB"
                     /locus_tag="spr1568"
                     /db_xref="GeneID:933454"
     CDS             1548764..1550218
                     /gene="scrB"
                     /locus_tag="spr1568"
                     /EC_number="3.2.1.26"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="NP_359160.1"
                     /db_xref="GI:15903610"
                     /db_xref="GeneID:933454"
     gene            1550199..1551164
                     /gene="scrR"
                     /locus_tag="spr1569"
                     /db_xref="GeneID:933292"
     CDS             1550199..1551164
                     /gene="scrR"
                     /locus_tag="spr1569"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose operon repressor"
                     /protein_id="NP_359161.1"
                     /db_xref="GI:15903611"
                     /db_xref="GeneID:933292"
     gene            complement(1551199..1552473)
                     /gene="mvaA"
                     /locus_tag="spr1570"
                     /db_xref="GeneID:932918"
     CDS             complement(1551199..1552473)
                     /gene="mvaA"
                     /locus_tag="spr1570"
                     /EC_number="1.1.1.88"
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-3-methylglutaryl-CoA reductase"
                     /protein_id="NP_359162.1"
                     /db_xref="GI:15903612"
                     /db_xref="GeneID:932918"
     gene            complement(1552473..1553669)
                     /gene="mvaS"
                     /locus_tag="spr1571"
                     /db_xref="GeneID:933931"
     CDS             complement(1552473..1553669)
                     /gene="mvaS"
                     /locus_tag="spr1571"
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="NP_359163.1"
                     /db_xref="GI:15903613"
                     /db_xref="GeneID:933931"
     gene            complement(1553776..1554063)
                     /locus_tag="spr1572"
                     /db_xref="GeneID:933874"
     CDS             complement(1553776..1554063)
                     /locus_tag="spr1572"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359164.1"
                     /db_xref="GI:15903614"
                     /db_xref="GeneID:933874"
     gene            complement(1554092..1554481)
                     /gene="IS1381"
                     /locus_tag="spr1573"
                     /db_xref="GeneID:933925"
     CDS             complement(1554092..1554481)
                     /gene="IS1381"
                     /locus_tag="spr1573"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_359165.1"
                     /db_xref="GI:15903615"
                     /db_xref="GeneID:933925"
     gene            complement(1554780..1555229)
                     /locus_tag="spr1575"
                     /db_xref="GeneID:933128"
     CDS             complement(1554780..1555229)
                     /locus_tag="spr1575"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359167.1"
                     /db_xref="GI:15903617"
                     /db_xref="GeneID:933128"
     gene            complement(1555231..1555989)
                     /locus_tag="spr1576"
                     /db_xref="GeneID:933309"
     CDS             complement(1555231..1555989)
                     /locus_tag="spr1576"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359168.1"
                     /db_xref="GI:15903618"
                     /db_xref="GeneID:933309"
     gene            complement(1556104..1558083)
                     /gene="pkn2"
                     /locus_tag="spr1577"
                     /db_xref="GeneID:933070"
     CDS             complement(1556104..1558083)
                     /gene="pkn2"
                     /locus_tag="spr1577"
                     /EC_number="2.7.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="NP_359169.1"
                     /db_xref="GI:15903619"
                     /db_xref="GeneID:933070"
     gene            complement(1558080..1558820)
                     /gene="pppL"
                     /locus_tag="spr1578"
                     /db_xref="GeneID:933328"
     CDS             complement(1558080..1558820)
                     /gene="pppL"
                     /locus_tag="spr1578"
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase"
                     /protein_id="NP_359170.1"
                     /db_xref="GI:15903620"
                     /db_xref="GeneID:933328"
     gene            complement(1558835..1560151)
                     /gene="sunL"
                     /locus_tag="spr1579"
                     /db_xref="GeneID:933344"
     CDS             complement(1558835..1560151)
                     /gene="sunL"
                     /locus_tag="spr1579"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA methylase"
                     /protein_id="NP_359171.1"
                     /db_xref="GI:15903621"
                     /db_xref="GeneID:933344"
     gene            complement(1560141..1561076)
                     /gene="fmt"
                     /locus_tag="spr1580"
                     /db_xref="GeneID:933459"
     CDS             complement(1560141..1561076)
                     /gene="fmt"
                     /locus_tag="spr1580"
                     /EC_number="2.1.2.9"
                     /note="modifies the free amino group of the aminoacyl
                     moiety of methionyl-tRNA(fMet) which is important in
                     translation initiation; inactivation of this gene in
                     Escherichia coli severely impairs growth"
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="NP_359172.1"
                     /db_xref="GI:15903622"
                     /db_xref="GeneID:933459"
     gene            complement(1561089..1563485)
                     /gene="priA"
                     /locus_tag="spr1581"
                     /db_xref="GeneID:933323"
     CDS             complement(1561089..1563485)
                     /gene="priA"
                     /locus_tag="spr1581"
                     /note="binding of PriA to forked DNA starts the assembly
                     of the primosome, also possesses 3'-5' helicase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="primosome assembly protein PriA"
                     /protein_id="NP_359173.1"
                     /db_xref="GI:15903623"
                     /db_xref="GeneID:933323"
     gene            complement(1563551..1563865)
                     /locus_tag="spr1582"
                     /db_xref="GeneID:933835"
     CDS             complement(1563551..1563865)
                     /locus_tag="spr1582"
                     /EC_number="2.7.7.6"
                     /note="Promotes RNA polymerase assembly. Latches the N-
                     and C-terminal regions of the beta' subunit thereby
                     facilitating its interaction with the beta and alpha
                     subunits"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="NP_359174.1"
                     /db_xref="GI:15903624"
                     /db_xref="GeneID:933835"
     gene            complement(1563890..1564516)
                     /gene="gmk"
                     /locus_tag="spr1583"
                     /db_xref="GeneID:933273"
     CDS             complement(1563890..1564516)
                     /gene="gmk"
                     /locus_tag="spr1583"
                     /EC_number="2.7.4.8"
                     /note="Essential for recycling GMP and indirectly, cGMP"
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="NP_359175.1"
                     /db_xref="GI:15903625"
                     /db_xref="GeneID:933273"
     gene            complement(1564646..1566259)
                     /locus_tag="spr1584"
                     /db_xref="GeneID:933269"
     CDS             complement(1564646..1566259)
                     /locus_tag="spr1584"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359176.1"
                     /db_xref="GI:15903626"
                     /db_xref="GeneID:933269"
     gene            complement(1566450..1566704)
                     /locus_tag="spr1585"
                     /db_xref="GeneID:933264"
     CDS             complement(1566450..1566704)
                     /locus_tag="spr1585"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359177.1"
                     /db_xref="GI:15903627"
                     /db_xref="GeneID:933264"
     gene            complement(1566708..1567001)
                     /locus_tag="spr1586"
                     /db_xref="GeneID:933314"
     CDS             complement(1566708..1567001)
                     /locus_tag="spr1586"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359178.1"
                     /db_xref="GI:15903628"
                     /db_xref="GeneID:933314"
     repeat_region   complement(1567052..1567160)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1567200..1568297)
                     /locus_tag="spr1587"
                     /db_xref="GeneID:933243"
     CDS             complement(1567200..1568297)
                     /locus_tag="spr1587"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359179.1"
                     /db_xref="GI:15903629"
                     /db_xref="GeneID:933243"
     gene            complement(1568307..1569053)
                     /locus_tag="spr1588"
                     /db_xref="GeneID:933287"
     CDS             complement(1568307..1569053)
                     /locus_tag="spr1588"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359180.1"
                     /db_xref="GI:15903630"
                     /db_xref="GeneID:933287"
     gene            complement(1569156..1569509)
                     /locus_tag="spr1589"
                     /db_xref="GeneID:933139"
     CDS             complement(1569156..1569509)
                     /locus_tag="spr1589"
                     /codon_start=1
                     /transl_table=11
                     /product="iojap-related protein"
                     /protein_id="NP_359181.1"
                     /db_xref="GI:15903631"
                     /db_xref="GeneID:933139"
     gene            complement(1569522..1570022)
                     /locus_tag="spr1590"
                     /db_xref="GeneID:933302"
     CDS             complement(1569522..1570022)
                     /locus_tag="spr1590"
                     /note="Similar to isochorismatase"
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismatase"
                     /protein_id="NP_359182.1"
                     /db_xref="GI:15903632"
                     /db_xref="GeneID:933302"
     gene            complement(1570023..1570616)
                     /locus_tag="spr1591"
                     /db_xref="GeneID:933060"
     CDS             complement(1570023..1570616)
                     /locus_tag="spr1591"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359183.1"
                     /db_xref="GI:15903633"
                     /db_xref="GeneID:933060"
     gene            complement(1570616..1571245)
                     /gene="nadD"
                     /locus_tag="spr1592"
                     /db_xref="GeneID:933444"
     CDS             complement(1570616..1571245)
                     /gene="nadD"
                     /locus_tag="spr1592"
                     /EC_number="2.7.7.18"
                     /note="transfers an adenyl group from ATP to NaMN to form
                     nicotinic acid adenine dinucleotide (NaAD) which is then
                     converted to the ubiquitous compound NAD by NAD
                     synthetase; essential enzyme in bacteria"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinic acid mononucleotide
                     adenylyltransferase"
                     /protein_id="NP_359184.1"
                     /db_xref="GI:15903634"
                     /db_xref="GeneID:933444"
     gene            complement(1571297..1571608)
                     /locus_tag="spr1593"
                     /db_xref="GeneID:933137"
     CDS             complement(1571297..1571608)
                     /locus_tag="spr1593"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359185.1"
                     /db_xref="GI:15903635"
                     /db_xref="GeneID:933137"
     gene            complement(1571823..1572929)
                     /locus_tag="spr1594"
                     /db_xref="GeneID:933397"
     CDS             complement(1571823..1572929)
                     /locus_tag="spr1594"
                     /note="in Bacillus subtilis this enzyme appears to be
                     involved in 30S ribosomal RNA subunit biogenesis"
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein YqeH"
                     /protein_id="NP_359186.1"
                     /db_xref="GI:15903636"
                     /db_xref="GeneID:933397"
     gene            complement(1572932..1573522)
                     /locus_tag="spr1595"
                     /db_xref="GeneID:933109"
     CDS             complement(1572932..1573522)
                     /locus_tag="spr1595"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359187.1"
                     /db_xref="GI:15903637"
                     /db_xref="GeneID:933109"
     gene            complement(1573474..1574370)
                     /gene="corA"
                     /locus_tag="spr1596"
                     /db_xref="GeneID:933228"
     CDS             complement(1573474..1574370)
                     /gene="corA"
                     /locus_tag="spr1596"
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium and cobalt transporter CorA"
                     /protein_id="NP_359188.1"
                     /db_xref="GI:15903638"
                     /db_xref="GeneID:933228"
     gene            complement(1574427..1575032)
                     /locus_tag="spr1597"
                     /db_xref="GeneID:933438"
     CDS             complement(1574427..1575032)
                     /locus_tag="spr1597"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359189.1"
                     /db_xref="GI:15903639"
                     /db_xref="GeneID:933438"
     gene            1575376..1576335
                     /gene="dctA"
                     /locus_tag="spr1598"
                     /db_xref="GeneID:933071"
     CDS             1575376..1576335
                     /gene="dctA"
                     /locus_tag="spr1598"
                     /note="involved in the import of serine and threonine
                     coupled with the import of sodium"
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="NP_359190.1"
                     /db_xref="GI:15903640"
                     /db_xref="GeneID:933071"
     gene            1576403..1577356
                     /locus_tag="spr1599"
                     /db_xref="GeneID:933402"
     CDS             1576403..1577356
                     /locus_tag="spr1599"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359191.1"
                     /db_xref="GI:15903641"
                     /db_xref="GeneID:933402"
     gene            1577455..1577880
                     /locus_tag="spr1600"
                     /db_xref="GeneID:933307"
     CDS             1577455..1577880
                     /locus_tag="spr1600"
                     /note="Probable transcription regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_359192.1"
                     /db_xref="GI:15903642"
                     /db_xref="GeneID:933307"
     gene            1577898..1578200
                     /locus_tag="spr1601"
                     /db_xref="GeneID:933432"
     CDS             1577898..1578200
                     /locus_tag="spr1601"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359193.1"
                     /db_xref="GI:15903643"
                     /db_xref="GeneID:933432"
     gene            1578217..1578531
                     /gene="trxA"
                     /locus_tag="spr1602"
                     /db_xref="GeneID:933436"
     CDS             1578217..1578531
                     /gene="trxA"
                     /locus_tag="spr1602"
                     /EC_number="1.8.1.9"
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="NP_359194.1"
                     /db_xref="GI:15903644"
                     /db_xref="GeneID:933436"
     repeat_region   1578606..1578712
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            1578797..1579369
                     /locus_tag="spr1603"
                     /db_xref="GeneID:933864"
     CDS             1578797..1579369
                     /locus_tag="spr1603"
                     /note="NADPH-dependent; catalyzes the reduction of
                     7-cyano-7-deazaguanine to 7-aminomethyl-7-deazaguanine in
                     queuosine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine reductase"
                     /protein_id="NP_359195.1"
                     /db_xref="GI:15903645"
                     /db_xref="GeneID:933864"
     repeat_region   complement(1579373..1579793)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbbbbbbbba"
     gene            1579381..1579824
                     /locus_tag="spr1603a"
                     /db_xref="GeneID:17374510"
     CDS             1579381..1579824
                     /locus_tag="spr1603a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719805.1"
                     /db_xref="GI:555247351"
                     /db_xref="GeneID:17374510"
     gene            complement(1579849..1580517)
                     /gene="aqpZ"
                     /locus_tag="spr1604"
                     /db_xref="GeneID:933893"
     CDS             complement(1579849..1580517)
                     /gene="aqpZ"
                     /locus_tag="spr1604"
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="NP_359196.1"
                     /db_xref="GI:15903646"
                     /db_xref="GeneID:933893"
     gene            complement(1580628..1581188)
                     /locus_tag="spr1605"
                     /db_xref="GeneID:934041"
     CDS             complement(1580628..1581188)
                     /locus_tag="spr1605"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359197.1"
                     /db_xref="GI:15903647"
                     /db_xref="GeneID:934041"
     gene            complement(1581428..1583224)
                     /gene="pepF"
                     /locus_tag="spr1606"
                     /db_xref="GeneID:933318"
     CDS             complement(1581428..1583224)
                     /gene="pepF"
                     /locus_tag="spr1606"
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="NP_359198.1"
                     /db_xref="GI:15903648"
                     /db_xref="GeneID:933318"
     gene            complement(1583235..1583990)
                     /locus_tag="spr1607"
                     /db_xref="GeneID:933160"
     CDS             complement(1583235..1583990)
                     /locus_tag="spr1607"
                     /note="in Escherichia coli RsmE methylates the N3 position
                     of the U1498 base in 16S rRNA; cells lacking this function
                     can grow, but are outcompeted by wild-type; SAM-dependent
                     m(3)U1498 methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="16S ribosomal RNA methyltransferase RsmE"
                     /protein_id="NP_359199.1"
                     /db_xref="GI:15903649"
                     /db_xref="GeneID:933160"
     gene            complement(1583980..1584930)
                     /gene="prmA"
                     /locus_tag="spr1608"
                     /db_xref="GeneID:934029"
     CDS             complement(1583980..1584930)
                     /gene="prmA"
                     /locus_tag="spr1608"
                     /EC_number="2.1.1.-"
                     /note="methylates ribosomal protein L11 at multiple amino
                     acid positions; mutations of these genes in Escherichia
                     coli or Thermus thermophilus has no apparent phenotype"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein L11 methyltransferase"
                     /protein_id="NP_359200.2"
                     /db_xref="GI:161410740"
                     /db_xref="GeneID:934029"
     gene            complement(1585068..1585496)
                     /gene="mutT"
                     /locus_tag="spr1609"
                     /db_xref="GeneID:933359"
     CDS             complement(1585068..1585496)
                     /gene="mutT"
                     /locus_tag="spr1609"
                     /EC_number="3.6.1.-"
                     /codon_start=1
                     /transl_table=11
                     /product="MutT/nudix family protein"
                     /protein_id="NP_359201.1"
                     /db_xref="GI:15903651"
                     /db_xref="GeneID:933359"
     gene            complement(1585462..1586580)
                     /locus_tag="spr1610"
                     /db_xref="GeneID:933498"
     CDS             complement(1585462..1586580)
                     /locus_tag="spr1610"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359202.1"
                     /db_xref="GI:15903652"
                     /db_xref="GeneID:933498"
     gene            complement(1586584..1587054)
                     /locus_tag="spr1611"
                     /db_xref="GeneID:933786"
     CDS             complement(1586584..1587054)
                     /locus_tag="spr1611"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359203.1"
                     /db_xref="GI:15903653"
                     /db_xref="GeneID:933786"
     gene            complement(1587345..1587797)
                     /locus_tag="spr1612"
                     /db_xref="GeneID:933845"
     CDS             complement(1587345..1587797)
                     /locus_tag="spr1612"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359204.1"
                     /db_xref="GI:15903654"
                     /db_xref="GeneID:933845"
     gene            complement(1587834..1588040)
                     /locus_tag="spr1613"
                     /db_xref="GeneID:933465"
     CDS             complement(1587834..1588040)
                     /locus_tag="spr1613"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359205.1"
                     /db_xref="GI:15903655"
                     /db_xref="GeneID:933465"
     gene            complement(1588150..1588329)
                     /locus_tag="spr1614"
                     /db_xref="GeneID:933308"
     CDS             complement(1588150..1588329)
                     /locus_tag="spr1614"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359206.1"
                     /db_xref="GI:15903656"
                     /db_xref="GeneID:933308"
     repeat_region   1588305..1588409
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     gene            complement(1588494..1588733)
                     /locus_tag="spr1615"
                     /db_xref="GeneID:933744"
     CDS             complement(1588494..1588733)
                     /locus_tag="spr1615"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359207.1"
                     /db_xref="GI:15903657"
                     /db_xref="GeneID:933744"
     gene            1589003..1590274
                     /gene="cshA"
                     /locus_tag="spr1616"
                     /db_xref="GeneID:933195"
     CDS             1589003..1590274
                     /gene="cshA"
                     /locus_tag="spr1616"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination factor protein RarA"
                     /protein_id="NP_359208.1"
                     /db_xref="GI:15903658"
                     /db_xref="GeneID:933195"
     gene            1590539..1590611
                     /gene="tRNA-Lys1"
                     /locus_tag="sprt11"
                     /db_xref="GeneID:933808"
     tRNA            1590539..1590611
                     /gene="tRNA-Lys1"
                     /locus_tag="sprt11"
                     /product="tRNA-Lys"
                     /db_xref="GeneID:933808"
     gene            complement(1590821..1592140)
                     /gene="sacA"
                     /locus_tag="spr1617"
                     /db_xref="GeneID:933211"
     CDS             complement(1590821..1592140)
                     /gene="sacA"
                     /locus_tag="spr1617"
                     /EC_number="3.2.1.26"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="NP_359209.1"
                     /db_xref="GI:15903659"
                     /db_xref="GeneID:933211"
     gene            complement(1592150..1593004)
                     /gene="ABC-MSP"
                     /locus_tag="spr1618"
                     /db_xref="GeneID:933483"
     CDS             complement(1592150..1593004)
                     /gene="ABC-MSP"
                     /locus_tag="spr1618"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359210.1"
                     /db_xref="GI:15903660"
                     /db_xref="GeneID:933483"
     gene            complement(1592997..1593905)
                     /gene="ABC-MSP"
                     /locus_tag="spr1619"
                     /db_xref="GeneID:932933"
     CDS             complement(1592997..1593905)
                     /gene="ABC-MSP"
                     /locus_tag="spr1619"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359211.1"
                     /db_xref="GI:15903661"
                     /db_xref="GeneID:932933"
     gene            complement(1593995..1595308)
                     /gene="ABC-SBP"
                     /locus_tag="spr1620"
                     /db_xref="GeneID:933745"
     CDS             complement(1593995..1595308)
                     /gene="ABC-SBP"
                     /locus_tag="spr1620"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="NP_359212.1"
                     /db_xref="GI:15903662"
                     /db_xref="GeneID:933745"
     gene            complement(1595432..1596445)
                     /gene="scrR"
                     /locus_tag="spr1621"
                     /db_xref="GeneID:933960"
     CDS             complement(1595432..1596445)
                     /gene="scrR"
                     /locus_tag="spr1621"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose operon repressor"
                     /protein_id="NP_359213.1"
                     /db_xref="GI:15903663"
                     /db_xref="GeneID:933960"
     gene            complement(1596789..1598327)
                     /locus_tag="spr1622"
                     /db_xref="GeneID:933678"
     CDS             complement(1596789..1598327)
                     /locus_tag="spr1622"
                     /note="regulator protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359214.1"
                     /db_xref="GI:15903664"
                     /db_xref="GeneID:933678"
     gene            1598954..1599526
                     /locus_tag="spr1623"
                     /db_xref="GeneID:932829"
     CDS             1598954..1599526
                     /locus_tag="spr1623"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359215.1"
                     /db_xref="GI:15903665"
                     /db_xref="GeneID:932829"
     gene            1599538..1599708
                     /locus_tag="spr1624"
                     /db_xref="GeneID:933828"
     CDS             1599538..1599708
                     /locus_tag="spr1624"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359216.1"
                     /db_xref="GI:15903666"
                     /db_xref="GeneID:933828"
     gene            1599747..1600355
                     /locus_tag="spr1625"
                     /db_xref="GeneID:933793"
     CDS             1599747..1600355
                     /locus_tag="spr1625"
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein 24"
                     /protein_id="NP_359217.1"
                     /db_xref="GI:15903667"
                     /db_xref="GeneID:933793"
     gene            1600386..1600589
                     /locus_tag="spr1626"
                     /db_xref="GeneID:933216"
     CDS             1600386..1600589
                     /locus_tag="spr1626"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359218.1"
                     /db_xref="GI:15903668"
                     /db_xref="GeneID:933216"
     repeat_region   complement(1601032..1601138)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1601116..1601562)
                     /locus_tag="spr1627"
                     /db_xref="GeneID:933262"
     CDS             complement(1601116..1601562)
                     /locus_tag="spr1627"
                     /note="Probable acetyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359219.1"
                     /db_xref="GI:15903669"
                     /db_xref="GeneID:933262"
     gene            1601632..1602291
                     /gene="pilD"
                     /locus_tag="spr1628"
                     /db_xref="GeneID:933620"
     CDS             1601632..1602291
                     /gene="pilD"
                     /locus_tag="spr1628"
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="type IV prepilin peptidase"
                     /protein_id="NP_359220.1"
                     /db_xref="GI:15903670"
                     /db_xref="GeneID:933620"
     gene            complement(1602343..1603494)
                     /locus_tag="spr1629"
                     /db_xref="GeneID:933063"
     CDS             complement(1602343..1603494)
                     /locus_tag="spr1629"
                     /note="DNA-binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_359221.1"
                     /db_xref="GI:15903671"
                     /db_xref="GeneID:933063"
     gene            complement(1603509..1604240)
                     /locus_tag="spr1630"
                     /db_xref="GeneID:933473"
     CDS             complement(1603509..1604240)
                     /locus_tag="spr1630"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359222.1"
                     /db_xref="GI:15903672"
                     /db_xref="GeneID:933473"
     gene            complement(1604542..1605318)
                     /gene="trpA"
                     /locus_tag="spr1631"
                     /db_xref="GeneID:933255"
     CDS             complement(1604542..1605318)
                     /gene="trpA"
                     /locus_tag="spr1631"
                     /EC_number="4.2.1.20"
                     /note="catalyzes the formation of indole and
                     glyceraldehyde 3-phosphate from indoleglycerol phosphate
                     in tryptophan biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="NP_359223.1"
                     /db_xref="GI:15903673"
                     /db_xref="GeneID:933255"
     gene            complement(1605311..1606534)
                     /gene="trpB"
                     /locus_tag="spr1632"
                     /db_xref="GeneID:933618"
     CDS             complement(1605311..1606534)
                     /gene="trpB"
                     /locus_tag="spr1632"
                     /EC_number="4.2.1.20"
                     /note="catalyzes the formation of L-tryptophan from
                     L-serine and 1-(indol-3-yl)glycerol 3-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="NP_359224.1"
                     /db_xref="GI:15903674"
                     /db_xref="GeneID:933618"
     gene            complement(1606512..1607141)
                     /gene="trpF"
                     /locus_tag="spr1633"
                     /db_xref="GeneID:933859"
     CDS             complement(1606512..1607141)
                     /gene="trpF"
                     /locus_tag="spr1633"
                     /EC_number="5.3.1.24"
                     /note="catalyzes the formation of
                     1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate
                     from N-(5-phospho-beta-D-ribosyl)-anthranilate in
                     tryptophan biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="N-(5'-phosphoribosyl)anthranilate isomerase"
                     /protein_id="NP_359225.1"
                     /db_xref="GI:15903675"
                     /db_xref="GeneID:933859"
     gene            complement(1607098..1607865)
                     /gene="trpC"
                     /locus_tag="spr1634"
                     /db_xref="GeneID:933756"
     CDS             complement(1607098..1607865)
                     /gene="trpC"
                     /locus_tag="spr1634"
                     /EC_number="4.1.1.48"
                     /note="involved in tryptophan biosynthesis; amino acid
                     biosynthesis; converts
                     1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to
                     C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide
                     and water"
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase"
                     /protein_id="NP_359226.1"
                     /db_xref="GI:15903676"
                     /db_xref="GeneID:933756"
     gene            complement(1607862..1608866)
                     /gene="trpD"
                     /locus_tag="spr1635"
                     /db_xref="GeneID:933836"
     CDS             complement(1607862..1608866)
                     /gene="trpD"
                     /locus_tag="spr1635"
                     /EC_number="2.4.2.18"
                     /note="Catalyzes the conversion of
                     N-(5-phospho-D-ribosyl)-anthranilate and diphosphate to
                     anthranilate and 5-phospho-alpha-D-ribose 1-diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="NP_359227.1"
                     /db_xref="GI:15903677"
                     /db_xref="GeneID:933836"
     gene            complement(1608877..1609443)
                     /gene="trpG"
                     /locus_tag="spr1636"
                     /db_xref="GeneID:933813"
     CDS             complement(1608877..1609443)
                     /gene="trpG"
                     /locus_tag="spr1636"
                     /EC_number="4.1.3.27"
                     /note="TrpG; with TrpE catalyzes the formation of
                     anthranilate and glutamate from chorismate and glutamine;
                     TrpG provides the glutamine amidotransferase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component II"
                     /protein_id="NP_359228.1"
                     /db_xref="GI:15903678"
                     /db_xref="GeneID:933813"
     gene            complement(1609440..1610801)
                     /gene="trpE"
                     /locus_tag="spr1637"
                     /db_xref="GeneID:933781"
     CDS             complement(1609440..1610801)
                     /gene="trpE"
                     /locus_tag="spr1637"
                     /EC_number="4.1.3.27"
                     /note="with component II, the glutamine amidotransferase,
                     catalyzes the formation of anthranilate from chorismate
                     and glutamine"
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="NP_359229.2"
                     /db_xref="GI:229000970"
                     /db_xref="GeneID:933781"
     repeat_region   1611191..1611386
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1611988..1612989)
                     /gene="ccpA"
                     /locus_tag="spr1639"
                     /db_xref="GeneID:933352"
     CDS             complement(1611988..1612989)
                     /gene="ccpA"
                     /locus_tag="spr1639"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein"
                     /protein_id="NP_359231.1"
                     /db_xref="GI:15903681"
                     /db_xref="GeneID:933352"
     gene            complement(1613097..1613465)
                     /locus_tag="spr1640"
                     /db_xref="GeneID:933345"
     CDS             complement(1613097..1613465)
                     /locus_tag="spr1640"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359232.1"
                     /db_xref="GI:15903682"
                     /db_xref="GeneID:933345"
     gene            complement(1613561..1614271)
                     /gene="mgtC"
                     /locus_tag="spr1641"
                     /db_xref="GeneID:933023"
     CDS             complement(1613561..1614271)
                     /gene="mgtC"
                     /locus_tag="spr1641"
                     /codon_start=1
                     /transl_table=11
                     /product="Mg2+ transporter"
                     /protein_id="NP_359233.1"
                     /db_xref="GI:15903683"
                     /db_xref="GeneID:933023"
     gene            complement(1614274..1615965)
                     /gene="ABC-MSP"
                     /locus_tag="spr1643"
                     /db_xref="GeneID:933624"
     CDS             complement(1614274..1615965)
                     /gene="ABC-MSP"
                     /locus_tag="spr1643"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359235.1"
                     /db_xref="GI:15903685"
                     /db_xref="GeneID:933624"
     gene            complement(1615977..1616987)
                     /gene="ABC-NBD"
                     /locus_tag="spr1644"
                     /db_xref="GeneID:933848"
     CDS             complement(1615977..1616987)
                     /gene="ABC-NBD"
                     /locus_tag="spr1644"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359236.1"
                     /db_xref="GI:15903686"
                     /db_xref="GeneID:933848"
     gene            complement(1617090..1618157)
                     /gene="ABC-SBP"
                     /locus_tag="spr1645"
                     /db_xref="GeneID:933166"
     CDS             complement(1617090..1618157)
                     /gene="ABC-SBP"
                     /locus_tag="spr1645"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="NP_359237.1"
                     /db_xref="GI:15903687"
                     /db_xref="GeneID:933166"
     gene            complement(1618182..1618841)
                     /locus_tag="spr1646"
                     /db_xref="GeneID:933543"
     CDS             complement(1618182..1618841)
                     /locus_tag="spr1646"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359238.1"
                     /db_xref="GI:15903688"
                     /db_xref="GeneID:933543"
     gene            complement(1619051..1620031)
                     /gene="galE"
                     /locus_tag="spr1647"
                     /db_xref="GeneID:933268"
     CDS             complement(1619051..1620031)
                     /gene="galE"
                     /locus_tag="spr1647"
                     /EC_number="5.1.3.2"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase"
                     /protein_id="NP_359239.1"
                     /db_xref="GI:15903689"
                     /db_xref="GeneID:933268"
     gene            complement(1620044..1621519)
                     /gene="galT"
                     /locus_tag="spr1648"
                     /db_xref="GeneID:932967"
     CDS             complement(1620044..1621519)
                     /gene="galT"
                     /locus_tag="spr1648"
                     /EC_number="2.7.7.12"
                     /note="catalyzes the formation of alpha-D-glucose
                     1-phosphate and UDP-galactose from UDP-glucose and
                     alpha-D-galactose 1-phosphate in galactose metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="NP_359240.1"
                     /db_xref="GI:15903690"
                     /db_xref="GeneID:932967"
     gene            complement(1621532..1622173)
                     /locus_tag="spr1649"
                     /db_xref="GeneID:933690"
     CDS             complement(1621532..1622173)
                     /locus_tag="spr1649"
                     /note="transcriptional regulator (phoU like)"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter PhoU"
                     /protein_id="NP_359241.1"
                     /db_xref="GI:15903691"
                     /db_xref="GeneID:933690"
     gene            complement(1622231..1623082)
                     /locus_tag="spr1650"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933186"
     repeat_region   1622696..1622802
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1623066..1625225)
                     /locus_tag="spr1652"
                     /db_xref="GeneID:933108"
     CDS             complement(1623066..1625225)
                     /locus_tag="spr1652"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor family protein"
                     /protein_id="NP_359244.1"
                     /db_xref="GI:15903694"
                     /db_xref="GeneID:933108"
     repeat_region   1625335..1625575
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     repeat_region   1625410..1625516
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1626356..1627609)
                     /locus_tag="spr1654"
                     /db_xref="GeneID:933440"
     CDS             complement(1626356..1627609)
                     /locus_tag="spr1654"
                     /note="role in biosynthesis of amino sugar"
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein"
                     /protein_id="NP_359246.1"
                     /db_xref="GI:15903696"
                     /db_xref="GeneID:933440"
     gene            complement(1627625..1628356)
                     /locus_tag="spr1655"
                     /db_xref="GeneID:932855"
     CDS             complement(1627625..1628356)
                     /locus_tag="spr1655"
                     /note="glycosyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="NP_359247.1"
                     /db_xref="GI:15903697"
                     /db_xref="GeneID:932855"
     repeat_region   complement(1628423..1628499)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1628490..1630241)
                     /gene="ABC-N/P"
                     /locus_tag="spr1656"
                     /db_xref="GeneID:934027"
     CDS             complement(1628490..1630241)
                     /gene="ABC-N/P"
                     /locus_tag="spr1656"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_359248.1"
                     /db_xref="GI:15903698"
                     /db_xref="GeneID:934027"
     gene            complement(1630231..1632015)
                     /gene="ABC-N/P"
                     /locus_tag="spr1657"
                     /db_xref="GeneID:934046"
     CDS             complement(1630231..1632015)
                     /gene="ABC-N/P"
                     /locus_tag="spr1657"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_359249.1"
                     /db_xref="GI:15903699"
                     /db_xref="GeneID:934046"
     repeat_region   complement(1632014..1632162)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1632631..1633087)
                     /locus_tag="spr1659"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933889"
     gene            1633221..1634048
                     /gene="exoA"
                     /locus_tag="spr1660"
                     /db_xref="GeneID:933227"
     CDS             1633221..1634048
                     /gene="exoA"
                     /locus_tag="spr1660"
                     /EC_number="3.1.11.2"
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease"
                     /protein_id="NP_359252.1"
                     /db_xref="GI:15903702"
                     /db_xref="GeneID:933227"
     gene            1634203..1634442
                     /locus_tag="spr1661"
                     /db_xref="GeneID:933082"
     CDS             1634203..1634442
                     /locus_tag="spr1661"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359253.1"
                     /db_xref="GI:15903703"
                     /db_xref="GeneID:933082"
     repeat_region   1634540..1634692
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            1635320..1635901
                     /gene="xpt"
                     /locus_tag="spr1662"
                     /db_xref="GeneID:934026"
     CDS             1635320..1635901
                     /gene="xpt"
                     /locus_tag="spr1662"
                     /EC_number="2.4.2.22"
                     /note="Catalyzes the transfer of the phosphoribosyl moiety
                     from 5-phospho--D-ribosyl-1-pyrophosphate (PRib-PP) to the
                     6-oxo-guanine and -xanthine"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="NP_359254.1"
                     /db_xref="GI:15903704"
                     /db_xref="GeneID:934026"
     gene            1635901..1637163
                     /gene="pbuX"
                     /locus_tag="spr1663"
                     /db_xref="GeneID:933092"
     CDS             1635901..1637163
                     /gene="pbuX"
                     /locus_tag="spr1663"
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine permease"
                     /protein_id="NP_359255.1"
                     /db_xref="GI:15903705"
                     /db_xref="GeneID:933092"
     gene            complement(1637214..1637675)
                     /gene="dpnD"
                     /locus_tag="spr1664"
                     /db_xref="GeneID:933798"
     CDS             complement(1637214..1637675)
                     /gene="dpnD"
                     /locus_tag="spr1664"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359256.1"
                     /db_xref="GI:15903706"
                     /db_xref="GeneID:933798"
     gene            complement(1637672..1638436)
                     /gene="dpnC"
                     /locus_tag="spr1665"
                     /db_xref="GeneID:933882"
     CDS             complement(1637672..1638436)
                     /gene="dpnC"
                     /locus_tag="spr1665"
                     /EC_number="3.1.21.4"
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction enzyme DpnI (dpnC)"
                     /protein_id="NP_359257.1"
                     /db_xref="GI:15903707"
                     /db_xref="REBASE:SpnRORF1665P"
                     /db_xref="GeneID:933882"
     gene            complement(1638617..1639042)
                     /locus_tag="spr1666"
                     /db_xref="GeneID:933648"
     CDS             complement(1638617..1639042)
                     /locus_tag="spr1666"
                     /note="Similar to E. coli PaaI protein involved in
                     phenylacetic acid degradation"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359258.1"
                     /db_xref="GI:15903708"
                     /db_xref="GeneID:933648"
     gene            complement(1639091..1640572)
                     /gene="galT"
                     /locus_tag="spr1667"
                     /db_xref="GeneID:933029"
     CDS             complement(1639091..1640572)
                     /gene="galT"
                     /locus_tag="spr1667"
                     /EC_number="2.7.7.12"
                     /note="catalyzes the formation of alpha-D-glucose
                     1-phosphate and UDP-galactose from UDP-glucose and
                     alpha-D-galactose 1-phosphate in galactose metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="NP_359259.1"
                     /db_xref="GI:15903709"
                     /db_xref="GeneID:933029"
     gene            complement(1640591..1641769)
                     /gene="galK"
                     /locus_tag="spr1668"
                     /db_xref="GeneID:933086"
     CDS             complement(1640591..1641769)
                     /gene="galK"
                     /locus_tag="spr1668"
                     /EC_number="2.7.1.6"
                     /note="catalyzes the formation of alpha-D-galactose
                     1-phosphate from D-galactose in galactose metabolism"
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="NP_359260.1"
                     /db_xref="GI:15903710"
                     /db_xref="GeneID:933086"
     gene            1641933..1642940
                     /gene="galR"
                     /locus_tag="spr1669"
                     /db_xref="GeneID:934048"
     CDS             1641933..1642940
                     /gene="galR"
                     /locus_tag="spr1669"
                     /codon_start=1
                     /transl_table=11
                     /product="regulator of gal operon GalR"
                     /protein_id="NP_359261.1"
                     /db_xref="GI:15903711"
                     /db_xref="GeneID:934048"
     gene            complement(1642986..1644023)
                     /gene="adhB"
                     /locus_tag="spr1670"
                     /db_xref="GeneID:933078"
     CDS             complement(1642986..1644023)
                     /gene="adhB"
                     /locus_tag="spr1670"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-containing alcohol dehydrogenase"
                     /protein_id="NP_359262.1"
                     /db_xref="GI:15903712"
                     /db_xref="GeneID:933078"
     gene            complement(1644024..1644377)
                     /locus_tag="spr1671"
                     /db_xref="GeneID:932950"
     CDS             complement(1644024..1644377)
                     /locus_tag="spr1671"
                     /note="Similar to transcriptional regulator (MerR family)"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359263.1"
                     /db_xref="GI:15903713"
                     /db_xref="GeneID:932950"
     gene            complement(1644621..1645520)
                     /gene="czcD"
                     /locus_tag="spr1672"
                     /db_xref="GeneID:933821"
     CDS             complement(1644621..1645520)
                     /gene="czcD"
                     /locus_tag="spr1672"
                     /codon_start=1
                     /transl_table=11
                     /product="cation efflux system protein"
                     /protein_id="NP_359264.1"
                     /db_xref="GI:15903714"
                     /db_xref="GeneID:933821"
     gene            1645644..1646180
                     /locus_tag="spr1673"
                     /db_xref="GeneID:933091"
     CDS             1645644..1646180
                     /locus_tag="spr1673"
                     /note="tetR-family transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359265.1"
                     /db_xref="GI:15903715"
                     /db_xref="GeneID:933091"
     gene            complement(1646347..1647156)
                     /locus_tag="spr1674"
                     /db_xref="GeneID:933875"
     CDS             complement(1646347..1647156)
                     /locus_tag="spr1674"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359266.1"
                     /db_xref="GI:15903716"
                     /db_xref="GeneID:933875"
     gene            1647556..1648074
                     /gene="IS1167"
                     /locus_tag="spr1675"
                     /db_xref="GeneID:933126"
     CDS             1647556..1648074
                     /gene="IS1167"
                     /locus_tag="spr1675"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_359267.1"
                     /db_xref="GI:15903717"
                     /db_xref="GeneID:933126"
     gene            complement(1648982..1650502)
                     /gene="proWX"
                     /locus_tag="spr1677"
                     /db_xref="GeneID:933005"
     CDS             complement(1648982..1650502)
                     /gene="proWX"
                     /locus_tag="spr1677"
                     /codon_start=1
                     /transl_table=11
                     /product="choline ABC transporter permease"
                     /protein_id="NP_359269.1"
                     /db_xref="GI:15903719"
                     /db_xref="GeneID:933005"
     gene            complement(1650495..1651223)
                     /gene="proV"
                     /locus_tag="spr1678"
                     /db_xref="GeneID:933246"
     CDS             complement(1650495..1651223)
                     /gene="proV"
                     /locus_tag="spr1678"
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter"
                     /protein_id="NP_359270.1"
                     /db_xref="GI:15903720"
                     /db_xref="GeneID:933246"
     gene            complement(1651238..1652002)
                     /locus_tag="spr1679"
                     /db_xref="GeneID:933998"
     CDS             complement(1651238..1652002)
                     /locus_tag="spr1679"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359271.1"
                     /db_xref="GI:15903721"
                     /db_xref="GeneID:933998"
     gene            complement(1652006..1652449)
                     /locus_tag="spr1680"
                     /db_xref="GeneID:934024"
     CDS             complement(1652006..1652449)
                     /locus_tag="spr1680"
                     /note="transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359272.1"
                     /db_xref="GI:15903722"
                     /db_xref="GeneID:934024"
     gene            complement(1653131..1653436)
                     /locus_tag="spr1681"
                     /db_xref="GeneID:932956"
     CDS             complement(1653131..1653436)
                     /locus_tag="spr1681"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359273.1"
                     /db_xref="GI:15903723"
                     /db_xref="GeneID:932956"
     gene            complement(1653449..1654513)
                     /gene="pepA"
                     /locus_tag="spr1682"
                     /db_xref="GeneID:932959"
     CDS             complement(1653449..1654513)
                     /gene="pepA"
                     /locus_tag="spr1682"
                     /EC_number="3.4.11.7"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="NP_359274.1"
                     /db_xref="GI:15903724"
                     /db_xref="GeneID:932959"
     repeat_region   1654813..1654886
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            1654914..1655615
                     /locus_tag="spr1683"
                     /db_xref="GeneID:933099"
     CDS             1654914..1655615
                     /locus_tag="spr1683"
                     /EC_number="5.1.3.2"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="NP_359275.1"
                     /db_xref="GI:15903725"
                     /db_xref="GeneID:933099"
     gene            1656023..1656997
                     /gene="fatD"
                     /locus_tag="spr1684"
                     /db_xref="GeneID:933870"
     CDS             1656023..1656997
                     /gene="fatD"
                     /locus_tag="spr1684"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter permease"
                     /protein_id="NP_359276.1"
                     /db_xref="GI:15903726"
                     /db_xref="GeneID:933870"
     gene            1656987..1657943
                     /gene="fatC"
                     /locus_tag="spr1685"
                     /db_xref="GeneID:932929"
     CDS             1656987..1657943
                     /gene="fatC"
                     /locus_tag="spr1685"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter permease"
                     /protein_id="NP_359277.1"
                     /db_xref="GI:15903727"
                     /db_xref="GeneID:932929"
     gene            1657940..1658692
                     /gene="fecE"
                     /locus_tag="spr1686"
                     /db_xref="GeneID:933979"
     CDS             1657940..1658692
                     /gene="fecE"
                     /locus_tag="spr1686"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter ATP-binding
                     protein"
                     /protein_id="NP_359278.1"
                     /db_xref="GI:15903728"
                     /db_xref="GeneID:933979"
     gene            1658788..1659753
                     /gene="fatB"
                     /locus_tag="spr1687"
                     /db_xref="GeneID:933306"
     CDS             1658788..1659753
                     /gene="fatB"
                     /locus_tag="spr1687"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-compound ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_359279.1"
                     /db_xref="GI:15903729"
                     /db_xref="GeneID:933306"
     repeat_region   complement(1659773..1659886)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1659978..1660220)
                     /locus_tag="spr1688"
                     /db_xref="GeneID:933934"
     CDS             complement(1659978..1660220)
                     /locus_tag="spr1688"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359280.1"
                     /db_xref="GI:15903730"
                     /db_xref="GeneID:933934"
     gene            complement(1660220..1660942)
                     /gene="rluB"
                     /locus_tag="spr1689"
                     /db_xref="GeneID:933891"
     CDS             complement(1660220..1660942)
                     /gene="rluB"
                     /locus_tag="spr1689"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     B"
                     /protein_id="NP_359281.1"
                     /db_xref="GI:15903731"
                     /db_xref="GeneID:933891"
     gene            complement(1660929..1661498)
                     /gene="scpB"
                     /locus_tag="spr1690"
                     /db_xref="GeneID:933665"
     CDS             complement(1660929..1661498)
                     /gene="scpB"
                     /locus_tag="spr1690"
                     /note="functions during chromosome segregation; may form a
                     condensin-like structure with SMC and ScpA; forms a
                     homodimer"
                     /codon_start=1
                     /transl_table=11
                     /product="segregation and condensation protein B"
                     /protein_id="NP_359282.1"
                     /db_xref="GI:15903732"
                     /db_xref="GeneID:933665"
     gene            complement(1661517..1662245)
                     /gene="scpA"
                     /locus_tag="spr1691"
                     /db_xref="GeneID:933770"
     CDS             complement(1661517..1662245)
                     /gene="scpA"
                     /locus_tag="spr1691"
                     /note="functions during chromosome segregation; may form a
                     condensin-like structure with SMC and ScpB"
                     /codon_start=1
                     /transl_table=11
                     /product="segregation and condensation protein A"
                     /protein_id="NP_359283.1"
                     /db_xref="GI:15903733"
                     /db_xref="GeneID:933770"
     gene            complement(1662245..1662985)
                     /gene="xerD"
                     /locus_tag="spr1692"
                     /db_xref="GeneID:932943"
     CDS             complement(1662245..1662985)
                     /gene="xerD"
                     /locus_tag="spr1692"
                     /note="site-specific tyrosine recombinase which cuts and
                     rejoins DNA molecules; binds cooperatively to specific DNA
                     consensus sites; forms a heterotetrameric complex with
                     XerC; XerCD exhibit similar sequences; essential to
                     convert chromosome dimers to monomers during cell division
                     and functions during plasmid segregation; cell division
                     protein FtsK may regulate the XerCD complex; enzyme from
                     Streptococcus group has unusual active site motifs"
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD-like
                     protein"
                     /protein_id="NP_359284.1"
                     /db_xref="GI:15903734"
                     /db_xref="GeneID:932943"
     gene            complement(1662976..1663437)
                     /locus_tag="spr1693"
                     /db_xref="GeneID:933937"
     CDS             complement(1662976..1663437)
                     /locus_tag="spr1693"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359285.1"
                     /db_xref="GI:15903735"
                     /db_xref="GeneID:933937"
     gene            complement(1663434..1663955)
                     /locus_tag="spr1694"
                     /db_xref="GeneID:932835"
     CDS             complement(1663434..1663955)
                     /locus_tag="spr1694"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359286.1"
                     /db_xref="GI:15903736"
                     /db_xref="GeneID:932835"
     gene            complement(1663931..1664902)
                     /locus_tag="spr1695"
                     /db_xref="GeneID:933028"
     CDS             complement(1663931..1664902)
                     /locus_tag="spr1695"
                     /note="HAM1-like protein; Rec-dependent growth; RgdB;
                     yggV; it is suspected that this protein functions to
                     remove misincorporated bases such as xanthine or
                     hypoxanthine"
                     /codon_start=1
                     /transl_table=11
                     /product="fused deoxyribonucleotide triphosphate
                     pyrophosphatase/hypothetical protein"
                     /protein_id="NP_359287.2"
                     /db_xref="GI:161410739"
                     /db_xref="GeneID:933028"
     gene            complement(1664899..1665693)
                     /gene="murI"
                     /locus_tag="spr1696"
                     /db_xref="GeneID:933741"
     CDS             complement(1664899..1665693)
                     /gene="murI"
                     /locus_tag="spr1696"
                     /EC_number="5.1.1.3"
                     /note="converts L-glutamate to D-glutamate, a component of
                     peptidoglycan"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="NP_359288.1"
                     /db_xref="GI:15903738"
                     /db_xref="GeneID:933741"
     gene            complement(1665900..1666202)
                     /locus_tag="spr1697"
                     /db_xref="GeneID:933041"
     CDS             complement(1665900..1666202)
                     /locus_tag="spr1697"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359289.1"
                     /db_xref="GI:15903739"
                     /db_xref="GeneID:933041"
     gene            complement(1666290..1667915)
                     /gene="dexS"
                     /locus_tag="spr1698"
                     /db_xref="GeneID:933881"
     CDS             complement(1666290..1667915)
                     /gene="dexS"
                     /locus_tag="spr1698"
                     /EC_number="3.2.1.11"
                     /note="Also highly similar to trehalose-6-phosphate
                     hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="dextran glucosidase"
                     /protein_id="NP_359290.1"
                     /db_xref="GI:15903740"
                     /db_xref="GeneID:933881"
     repeat_region   complement(1667978..1668094)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1668093..1670210)
                     /gene="treP"
                     /locus_tag="spr1699"
                     /db_xref="GeneID:933714"
     CDS             complement(1668093..1670210)
                     /gene="treP"
                     /locus_tag="spr1699"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific transporter
                     subunit IIBC"
                     /protein_id="NP_359291.1"
                     /db_xref="GI:15903741"
                     /db_xref="GeneID:933714"
     gene            1670245..1670955
                     /gene="treR"
                     /locus_tag="spr1700"
                     /db_xref="GeneID:933116"
     CDS             1670245..1670955
                     /gene="treR"
                     /locus_tag="spr1700"
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon transcriptional repressor"
                     /protein_id="NP_359292.1"
                     /db_xref="GI:15903742"
                     /db_xref="GeneID:933116"
     gene            complement(1672492..1673463)
                     /gene="amiF"
                     /locus_tag="spr1703"
                     /db_xref="GeneID:932969"
     CDS             complement(1672492..1673463)
                     /gene="amiF"
                     /locus_tag="spr1703"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter ATP-binding protein
                     AmiF"
                     /protein_id="NP_359295.1"
                     /db_xref="GI:15903745"
                     /db_xref="GeneID:932969"
     gene            complement(1673429..1674496)
                     /gene="amiE"
                     /locus_tag="spr1704"
                     /db_xref="GeneID:934004"
     CDS             complement(1673429..1674496)
                     /gene="amiE"
                     /locus_tag="spr1704"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter ATP-binding protein
                     AmiE"
                     /protein_id="NP_359296.1"
                     /db_xref="GI:15903746"
                     /db_xref="GeneID:934004"
     gene            complement(1674505..1675431)
                     /gene="amiD"
                     /locus_tag="spr1705"
                     /db_xref="GeneID:932913"
     CDS             complement(1674505..1675431)
                     /gene="amiD"
                     /locus_tag="spr1705"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease AmiD"
                     /protein_id="NP_359297.1"
                     /db_xref="GI:15903747"
                     /db_xref="GeneID:932913"
     gene            complement(1675431..1676927)
                     /gene="amiC"
                     /locus_tag="spr1706"
                     /db_xref="GeneID:933016"
     CDS             complement(1675431..1676927)
                     /gene="amiC"
                     /locus_tag="spr1706"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease AmiC"
                     /protein_id="NP_359298.1"
                     /db_xref="GI:15903748"
                     /db_xref="GeneID:933016"
     gene            complement(1676994..1678973)
                     /gene="amiA"
                     /locus_tag="spr1707"
                     /db_xref="GeneID:933861"
     CDS             complement(1676994..1678973)
                     /gene="amiA"
                     /locus_tag="spr1707"
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="NP_359299.1"
                     /db_xref="GI:15903749"
                     /db_xref="GeneID:933861"
     gene            complement(1679660..1680853)
                     /locus_tag="spr1708"
                     /db_xref="GeneID:932951"
     CDS             complement(1679660..1680853)
                     /locus_tag="spr1708"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359300.1"
                     /db_xref="GI:15903750"
                     /db_xref="GeneID:932951"
     gene            complement(1680991..1682433)
                     /gene="gtfA"
                     /locus_tag="spr1709"
                     /db_xref="GeneID:933971"
     CDS             complement(1680991..1682433)
                     /gene="gtfA"
                     /locus_tag="spr1709"
                     /EC_number="2.4.1.5"
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="NP_359301.1"
                     /db_xref="GI:15903751"
                     /db_xref="GeneID:933971"
     gene            complement(1682617..1682784)
                     /locus_tag="spr1709a"
                     /db_xref="GeneID:17374511"
     CDS             complement(1682617..1682784)
                     /locus_tag="spr1709a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719806.1"
                     /db_xref="GI:555247352"
                     /db_xref="GeneID:17374511"
     repeat_region   1682639..1682789
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(1682791..1683624)
                     /gene="msmG"
                     /locus_tag="spr1710"
                     /db_xref="GeneID:933978"
     CDS             complement(1682791..1683624)
                     /gene="msmG"
                     /locus_tag="spr1710"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359302.1"
                     /db_xref="GI:15903752"
                     /db_xref="GeneID:933978"
     gene            complement(1683638..1684528)
                     /gene="msmF"
                     /locus_tag="spr1711"
                     /db_xref="GeneID:933920"
     CDS             complement(1683638..1684528)
                     /gene="msmF"
                     /locus_tag="spr1711"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="NP_359303.1"
                     /db_xref="GI:15903753"
                     /db_xref="GeneID:933920"
     gene            complement(1684518..1685777)
                     /gene="msmE"
                     /locus_tag="spr1712"
                     /db_xref="GeneID:933919"
     CDS             complement(1684518..1685777)
                     /gene="msmE"
                     /locus_tag="spr1712"
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="NP_359304.1"
                     /db_xref="GI:15903754"
                     /db_xref="GeneID:933919"
     gene            complement(1685869..1688031)
                     /gene="aga"
                     /locus_tag="spr1713"
                     /db_xref="GeneID:933461"
     CDS             complement(1685869..1688031)
                     /gene="aga"
                     /locus_tag="spr1713"
                     /EC_number="3.2.1.22"
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="NP_359305.1"
                     /db_xref="GI:15903755"
                     /db_xref="GeneID:933461"
     gene            1688139..1688999
                     /gene="msmR"
                     /locus_tag="spr1714"
                     /db_xref="GeneID:932882"
     CDS             1688139..1688999
                     /gene="msmR"
                     /locus_tag="spr1714"
                     /codon_start=1
                     /transl_table=11
                     /product="MSM (multiple sugar metabolism) operon
                     regulatory protein"
                     /protein_id="NP_359306.1"
                     /db_xref="GI:15903756"
                     /db_xref="GeneID:932882"
     gene            1688996..1689931
                     /gene="birA"
                     /locus_tag="spr1715"
                     /db_xref="GeneID:933753"
     CDS             1688996..1689931
                     /gene="birA"
                     /locus_tag="spr1715"
                     /EC_number="6.3.4.15"
                     /note="catalyzes the formation of biotinyl-5'-AMP, also
                     acts as a transcriptional repressor of the biotin operon"
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--protein ligase"
                     /protein_id="NP_359307.1"
                     /db_xref="GI:15903757"
                     /db_xref="GeneID:933753"
     gene            complement(1690783..1690870)
                     /gene="tRNA-Ser2"
                     /locus_tag="sprt12"
                     /db_xref="GeneID:932939"
     tRNA            complement(1690783..1690870)
                     /gene="tRNA-Ser2"
                     /locus_tag="sprt12"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:932939"
     gene            complement(1690877..1690950)
                     /gene="tRNA-Ile1"
                     /locus_tag="sprt13"
                     /db_xref="GeneID:933872"
     tRNA            complement(1690877..1690950)
                     /gene="tRNA-Ile1"
                     /locus_tag="sprt13"
                     /product="tRNA-Ile"
                     /db_xref="GeneID:933872"
     gene            complement(1690986..1691056)
                     /gene="tRNA-Gly1"
                     /locus_tag="sprt14"
                     /db_xref="GeneID:933434"
     tRNA            complement(1690986..1691056)
                     /gene="tRNA-Gly1"
                     /locus_tag="sprt14"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:933434"
     gene            complement(1691076..1691148)
                     /gene="tRNA-Phe1"
                     /locus_tag="sprt15"
                     /db_xref="GeneID:933275"
     tRNA            complement(1691076..1691148)
                     /gene="tRNA-Phe1"
                     /locus_tag="sprt15"
                     /product="tRNA-Phe"
                     /db_xref="GeneID:933275"
     gene            complement(1691152..1691225)
                     /gene="tRNA-Met1"
                     /locus_tag="sprt16"
                     /db_xref="GeneID:933222"
     tRNA            complement(1691152..1691225)
                     /gene="tRNA-Met1"
                     /locus_tag="sprt16"
                     /product="tRNA-Met"
                     /db_xref="GeneID:933222"
     gene            complement(1691239..1691328)
                     /gene="tRNA-Ser3"
                     /locus_tag="sprt17"
                     /db_xref="GeneID:933479"
     tRNA            complement(1691239..1691328)
                     /gene="tRNA-Ser3"
                     /locus_tag="sprt17"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:933479"
     gene            complement(1691339..1691412)
                     /gene="tRNA-Met2"
                     /locus_tag="sprt18"
                     /db_xref="GeneID:933742"
     tRNA            complement(1691339..1691412)
                     /gene="tRNA-Met2"
                     /locus_tag="sprt18"
                     /product="tRNA-Met"
                     /db_xref="GeneID:933742"
     gene            complement(1691426..1691499)
                     /gene="tRNA-Met3"
                     /locus_tag="sprt19"
                     /db_xref="GeneID:933594"
     tRNA            complement(1691426..1691499)
                     /gene="tRNA-Met3"
                     /locus_tag="sprt19"
                     /product="tRNA-Met"
                     /db_xref="GeneID:933594"
     gene            complement(1691505..1691578)
                     /gene="tRNA-Pro1"
                     /locus_tag="sprt20"
                     /db_xref="GeneID:933818"
     tRNA            complement(1691505..1691578)
                     /gene="tRNA-Pro1"
                     /locus_tag="sprt20"
                     /product="tRNA-Pro"
                     /db_xref="GeneID:933818"
     gene            complement(1691594..1691667)
                     /gene="tRNA-Arg3"
                     /locus_tag="sprt21"
                     /db_xref="GeneID:932920"
     tRNA            complement(1691594..1691667)
                     /gene="tRNA-Arg3"
                     /locus_tag="sprt21"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:932920"
     gene            complement(1691677..1691762)
                     /gene="tRNA-Leu2"
                     /locus_tag="sprt22"
                     /db_xref="GeneID:933042"
     tRNA            complement(1691677..1691762)
                     /gene="tRNA-Leu2"
                     /locus_tag="sprt22"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:933042"
     gene            complement(1691770..1691841)
                     /gene="tRNA-Gly2"
                     /locus_tag="sprt23"
                     /db_xref="GeneID:933423"
     tRNA            complement(1691770..1691841)
                     /gene="tRNA-Gly2"
                     /locus_tag="sprt23"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:933423"
     gene            complement(1691864..1691936)
                     /gene="tRNA-Thr2"
                     /locus_tag="sprt24"
                     /db_xref="GeneID:933850"
     tRNA            complement(1691864..1691936)
                     /gene="tRNA-Thr2"
                     /locus_tag="sprt24"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:933850"
     gene            complement(1691955..1692036)
                     /gene="tRNA-Leu3"
                     /locus_tag="sprt25"
                     /db_xref="GeneID:932907"
     tRNA            complement(1691955..1692036)
                     /gene="tRNA-Leu3"
                     /locus_tag="sprt25"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:932907"
     gene            complement(1692042..1692114)
                     /gene="tRNA-Lys2"
                     /locus_tag="sprt26"
                     /db_xref="GeneID:933625"
     tRNA            complement(1692042..1692114)
                     /gene="tRNA-Lys2"
                     /locus_tag="sprt26"
                     /product="tRNA-Lys"
                     /db_xref="GeneID:933625"
     gene            complement(1692139..1692211)
                     /gene="tRNA-Asp1"
                     /locus_tag="sprt27"
                     /db_xref="GeneID:933439"
     tRNA            complement(1692139..1692211)
                     /gene="tRNA-Asp1"
                     /locus_tag="sprt27"
                     /product="tRNA-Asp"
                     /db_xref="GeneID:933439"
     gene            complement(1692214..1692286)
                     /gene="tRNA-Val1"
                     /locus_tag="sprt28"
                     /db_xref="GeneID:933740"
     tRNA            complement(1692214..1692286)
                     /gene="tRNA-Val1"
                     /locus_tag="sprt28"
                     /product="tRNA-Val"
                     /db_xref="GeneID:933740"
     gene            complement(1692291..1692405)
                     /gene="rRNA_5S-2"
                     /locus_tag="sprr04"
                     /db_xref="GeneID:933193"
     rRNA            complement(1692291..1692405)
                     /gene="rRNA_5S-2"
                     /locus_tag="sprr04"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:933193"
     gene            complement(1692483..1695384)
                     /gene="rRNA_23S-2"
                     /locus_tag="sprr05"
                     /db_xref="GeneID:933702"
     rRNA            complement(1692483..1695384)
                     /gene="rRNA_23S-2"
                     /locus_tag="sprr05"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:933702"
     gene            complement(1695509..1695581)
                     /gene="tRNA-Ala2"
                     /locus_tag="sprt29"
                     /db_xref="GeneID:933089"
     tRNA            complement(1695509..1695581)
                     /gene="tRNA-Ala2"
                     /locus_tag="sprt29"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:933089"
     gene            complement(1695655..1697168)
                     /gene="rRNA_16S-2"
                     /locus_tag="sprr06"
                     /db_xref="GeneID:933007"
     rRNA            complement(1695655..1697168)
                     /gene="rRNA_16S-2"
                     /locus_tag="sprr06"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:933007"
     gene            complement(1697431..1697502)
                     /gene="tRNA-Glu2"
                     /locus_tag="sprt30"
                     /db_xref="GeneID:933358"
     tRNA            complement(1697431..1697502)
                     /gene="tRNA-Glu2"
                     /locus_tag="sprt30"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:933358"
     gene            complement(1697564..1698919)
                     /locus_tag="spr1717"
                     /db_xref="GeneID:933414"
     CDS             complement(1697564..1698919)
                     /locus_tag="spr1717"
                     /note="Similar to RNA methyltransferase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359309.1"
                     /db_xref="GI:15903759"
                     /db_xref="GeneID:933414"
     gene            1698957..1699733
                     /gene="recX"
                     /locus_tag="spr1718"
                     /db_xref="GeneID:933158"
     CDS             1698957..1699733
                     /gene="recX"
                     /locus_tag="spr1718"
                     /note="binds RecA and inhibits RecA-mediated DNA strand
                     exchange and ATP hydrolysis and coprotease activities"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="NP_359310.2"
                     /db_xref="GI:161410738"
                     /db_xref="GeneID:933158"
     gene            1699822..1700355
                     /locus_tag="spr1719"
                     /db_xref="GeneID:933375"
     CDS             1699822..1700355
                     /locus_tag="spr1719"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359311.1"
                     /db_xref="GI:15903761"
                     /db_xref="GeneID:933375"
     gene            complement(1700709..1700915)
                     /locus_tag="spr1720"
                     /db_xref="GeneID:933040"
     CDS             complement(1700709..1700915)
                     /locus_tag="spr1720"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359312.1"
                     /db_xref="GI:15903762"
                     /db_xref="GeneID:933040"
     gene            1701075..1702304
                     /locus_tag="spr1721"
                     /db_xref="GeneID:933774"
     CDS             1701075..1702304
                     /locus_tag="spr1721"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_359313.1"
                     /db_xref="GI:15903763"
                     /db_xref="GeneID:933774"
     gene            complement(1702403..1704025)
                     /gene="groEL"
                     /locus_tag="spr1722"
                     /db_xref="GeneID:932997"
     CDS             complement(1702403..1704025)
                     /gene="groEL"
                     /locus_tag="spr1722"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; many bacteria have multiple
                     copies of the groEL gene which are active under different
                     environmental conditions; the B.japonicum protein in this
                     cluster is expressed constitutively; in Rhodobacter,
                     Corynebacterium and Rhizobium this protein is essential
                     for growth"
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone GroEL"
                     /protein_id="NP_359314.1"
                     /db_xref="GI:15903764"
                     /db_xref="GeneID:932997"
     gene            complement(1704041..1704325)
                     /gene="groES"
                     /locus_tag="spr1723"
                     /db_xref="GeneID:933334"
     CDS             complement(1704041..1704325)
                     /gene="groES"
                     /locus_tag="spr1723"
                     /note="10 kDa chaperonin; Cpn10; GroES; forms
                     homoheptameric ring; binds to one or both ends of the
                     GroEL double barrel in the presence of adenine nucleotides
                     capping it; folding of unfolded substrates initiates in a
                     GroEL-substrate bound and capped by GroES; release of the
                     folded substrate is dependent on ATP binding and
                     hydrolysis in the trans ring"
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperonin GroES"
                     /protein_id="NP_359315.1"
                     /db_xref="GI:15903765"
                     /db_xref="GeneID:933334"
     gene            complement(1704481..1704876)
                     /gene="ssbB"
                     /locus_tag="spr1724"
                     /db_xref="GeneID:933820"
     CDS             complement(1704481..1704876)
                     /gene="ssbB"
                     /locus_tag="spr1724"
                     /note="binds to single stranded DNA and may facilitate the
                     binding and interaction of other proteins to DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="NP_359316.1"
                     /db_xref="GI:15903766"
                     /db_xref="GeneID:933820"
     gene            complement(1704954..1705715)
                     /gene="ydfG"
                     /locus_tag="spr1725"
                     /db_xref="GeneID:933630"
     CDS             complement(1704954..1705715)
                     /gene="ydfG"
                     /locus_tag="spr1725"
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="NP_359317.1"
                     /db_xref="GI:15903767"
                     /db_xref="GeneID:933630"
     gene            complement(1705748..1706374)
                     /locus_tag="spr1726"
                     /db_xref="GeneID:933705"
     CDS             complement(1705748..1706374)
                     /locus_tag="spr1726"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359318.1"
                     /db_xref="GI:15903768"
                     /db_xref="GeneID:933705"
     gene            complement(1706390..1706707)
                     /locus_tag="spr1727"
                     /db_xref="GeneID:933577"
     CDS             complement(1706390..1706707)
                     /locus_tag="spr1727"
                     /note="Similar to thioredoxin H1"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359319.1"
                     /db_xref="GI:15903769"
                     /db_xref="GeneID:933577"
     gene            complement(1706704..1707003)
                     /locus_tag="spr1728"
                     /db_xref="GeneID:932863"
     CDS             complement(1706704..1707003)
                     /locus_tag="spr1728"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359320.1"
                     /db_xref="GI:15903770"
                     /db_xref="GeneID:932863"
     repeat_region   complement(1707084..1707245)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1707692..1708366)
                     /locus_tag="spr1730"
                     /db_xref="GeneID:933706"
     CDS             complement(1707692..1708366)
                     /locus_tag="spr1730"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359322.1"
                     /db_xref="GI:15903772"
                     /db_xref="GeneID:933706"
     gene            complement(1708372..1708821)
                     /locus_tag="spr1731"
                     /db_xref="GeneID:933697"
     CDS             complement(1708372..1708821)
                     /locus_tag="spr1731"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359323.1"
                     /db_xref="GI:15903773"
                     /db_xref="GeneID:933697"
     gene            complement(1708932..1709435)
                     /locus_tag="spr1732"
                     /db_xref="GeneID:933704"
     CDS             complement(1708932..1709435)
                     /locus_tag="spr1732"
                     /note="Similar to bacteriocin transport permease"
                     /codon_start=1
                     /transl_table=11
                     /product="PAP2 family protein"
                     /protein_id="NP_359324.1"
                     /db_xref="GI:15903774"
                     /db_xref="GeneID:933704"
     gene            complement(1709432..1709794)
                     /locus_tag="spr1733"
                     /db_xref="GeneID:933703"
     CDS             complement(1709432..1709794)
                     /locus_tag="spr1733"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359325.1"
                     /db_xref="GI:15903775"
                     /db_xref="GeneID:933703"
     gene            complement(1709860..1710891)
                     /locus_tag="spr1734"
                     /db_xref="GeneID:933695"
     CDS             complement(1709860..1710891)
                     /locus_tag="spr1734"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359326.1"
                     /db_xref="GI:15903776"
                     /db_xref="GeneID:933695"
     gene            complement(1710898..1711719)
                     /gene="ABC-NBD-truncation"
                     /locus_tag="spr1735"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933701"
     gene            complement(1711758..1712205)
                     /locus_tag="spr1737"
                     /db_xref="GeneID:933691"
     gene            complement(1712329..1713045)
                     /locus_tag="spr1738"
                     /db_xref="GeneID:933696"
     CDS             complement(1712329..1713045)
                     /locus_tag="spr1738"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359330.1"
                     /db_xref="GI:15903780"
                     /db_xref="GeneID:933696"
     repeat_region   complement(1713447..1713559)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1713926..1715341)
                     /gene="ply"
                     /locus_tag="spr1739"
                     /db_xref="GeneID:933687"
     CDS             complement(1713926..1715341)
                     /gene="ply"
                     /locus_tag="spr1739"
                     /codon_start=1
                     /transl_table=11
                     /product="pneumolysin"
                     /protein_id="NP_359331.1"
                     /db_xref="GI:15903781"
                     /db_xref="GeneID:933687"
     gene            complement(1715352..1715762)
                     /locus_tag="spr1740"
                     /db_xref="GeneID:933693"
     CDS             complement(1715352..1715762)
                     /locus_tag="spr1740"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359332.1"
                     /db_xref="GI:15903782"
                     /db_xref="GeneID:933693"
     gene            complement(1715755..1716363)
                     /locus_tag="spr1741"
                     /db_xref="GeneID:933692"
     CDS             complement(1715755..1716363)
                     /locus_tag="spr1741"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359333.1"
                     /db_xref="GI:15903783"
                     /db_xref="GeneID:933692"
     gene            complement(1716376..1716833)
                     /locus_tag="spr1742"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933684"
     repeat_region   1717792..1717898
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1718122..1718382)
                     /locus_tag="spr1746"
                     /db_xref="GeneID:933685"
     CDS             complement(1718122..1718382)
                     /locus_tag="spr1746"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359338.1"
                     /db_xref="GI:15903788"
                     /db_xref="GeneID:933685"
     repeat_region   complement(1718411..1718524)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1718441..1718995)
                     /locus_tag="spr1747"
                     /db_xref="GeneID:933683"
     CDS             complement(1718441..1718995)
                     /locus_tag="spr1747"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359339.1"
                     /db_xref="GI:15903789"
                     /db_xref="GeneID:933683"
     gene            complement(1718982..1719179)
                     /locus_tag="spr1748"
                     /db_xref="GeneID:933682"
     CDS             complement(1718982..1719179)
                     /locus_tag="spr1748"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359340.1"
                     /db_xref="GI:15903790"
                     /db_xref="GeneID:933682"
     gene            complement(1719183..1719977)
                     /locus_tag="spr1749"
                     /db_xref="GeneID:933674"
     CDS             complement(1719183..1719977)
                     /locus_tag="spr1749"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359341.1"
                     /db_xref="GI:15903791"
                     /db_xref="GeneID:933674"
     gene            complement(1720262..1720810)
                     /locus_tag="spr1750"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933679"
     gene            complement(1720939..1721298)
                     /locus_tag="spr1751"
                     /db_xref="GeneID:933677"
     CDS             complement(1720939..1721298)
                     /locus_tag="spr1751"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359343.1"
                     /db_xref="GI:15903793"
                     /db_xref="GeneID:933677"
     gene            complement(1721344..1721586)
                     /locus_tag="spr1752"
                     /db_xref="GeneID:933671"
     CDS             complement(1721344..1721586)
                     /locus_tag="spr1752"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359344.1"
                     /db_xref="GI:15903794"
                     /db_xref="GeneID:933671"
     gene            complement(1721537..1721710)
                     /locus_tag="spr1753"
                     /db_xref="GeneID:933676"
     CDS             complement(1721537..1721710)
                     /locus_tag="spr1753"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359345.1"
                     /db_xref="GI:15903795"
                     /db_xref="GeneID:933676"
     repeat_region   1721849..1721869
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            complement(1722069..1723025)
                     /gene="lytA"
                     /locus_tag="spr1754"
                     /db_xref="GeneID:933669"
     CDS             complement(1722069..1723025)
                     /gene="lytA"
                     /locus_tag="spr1754"
                     /EC_number="3.5.1.28"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="NP_359346.1"
                     /db_xref="GI:15903796"
                     /db_xref="GeneID:933669"
     gene            complement(1723401..1724771)
                     /gene="dinF"
                     /locus_tag="spr1756"
                     /db_xref="GeneID:933672"
     CDS             complement(1723401..1724771)
                     /gene="dinF"
                     /locus_tag="spr1756"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE efflux family protein DinF"
                     /protein_id="NP_359348.1"
                     /db_xref="GI:15903798"
                     /db_xref="GeneID:933672"
     repeat_region   complement(1724837..1724907)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     repeat_region   1724937..1725010
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b"
     gene            complement(1725078..1726244)
                     /gene="recA"
                     /locus_tag="spr1757"
                     /db_xref="GeneID:933670"
     CDS             complement(1725078..1726244)
                     /gene="recA"
                     /locus_tag="spr1757"
                     /EC_number="3.4.21.88"
                     /note="catalyzes the hydrolysis of ATP in the presence of
                     single-stranded DNA, the ATP-dependent uptake of
                     single-stranded DNA by duplex DNA, and the ATP-dependent
                     hybridization of homologous single-stranded DNAs"
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase A"
                     /protein_id="NP_359349.1"
                     /db_xref="GI:15903799"
                     /db_xref="GeneID:933670"
     gene            complement(1726299..1727555)
                     /gene="cinA"
                     /locus_tag="spr1758"
                     /db_xref="GeneID:933663"
     CDS             complement(1726299..1727555)
                     /gene="cinA"
                     /locus_tag="spr1758"
                     /note="Competence induced protein A"
                     /codon_start=1
                     /transl_table=11
                     /product="competence damage-inducible protein A"
                     /protein_id="NP_359350.1"
                     /db_xref="GI:15903800"
                     /db_xref="GeneID:933663"
     gene            complement(1727640..1728656)
                     /gene="lytR"
                     /locus_tag="spr1759"
                     /db_xref="GeneID:933667"
     CDS             complement(1727640..1728656)
                     /gene="lytR"
                     /locus_tag="spr1759"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_359351.1"
                     /db_xref="GI:15903801"
                     /db_xref="GeneID:933667"
     gene            complement(1728664..1729182)
                     /locus_tag="spr1760"
                     /db_xref="GeneID:933666"
     CDS             complement(1728664..1729182)
                     /locus_tag="spr1760"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359352.1"
                     /db_xref="GI:15903802"
                     /db_xref="GeneID:933666"
     gene            complement(1729172..1729615)
                     /locus_tag="spr1761"
                     /db_xref="GeneID:933660"
     CDS             complement(1729172..1729615)
                     /locus_tag="spr1761"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359353.1"
                     /db_xref="GI:15903803"
                     /db_xref="GeneID:933660"
     gene            complement(1729701..1730321)
                     /locus_tag="spr1762"
                     /db_xref="GeneID:933664"
     CDS             complement(1729701..1730321)
                     /locus_tag="spr1762"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359354.1"
                     /db_xref="GI:15903804"
                     /db_xref="GeneID:933664"
     repeat_region   complement(1730422..1730530)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1730704..1731567)
                     /gene="plcR"
                     /locus_tag="spr1763"
                     /db_xref="GeneID:933657"
     CDS             complement(1730704..1731567)
                     /gene="plcR"
                     /locus_tag="spr1763"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator"
                     /protein_id="NP_359355.1"
                     /db_xref="GI:15903805"
                     /db_xref="GeneID:933657"
     gene            1731759..1731929
                     /locus_tag="spr1764"
                     /db_xref="GeneID:933662"
     CDS             1731759..1731929
                     /locus_tag="spr1764"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359356.1"
                     /db_xref="GI:15903806"
                     /db_xref="GeneID:933662"
     gene            1732032..1732256
                     /locus_tag="spr1765"
                     /db_xref="GeneID:933661"
     CDS             1732032..1732256
                     /locus_tag="spr1765"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359357.1"
                     /db_xref="GI:15903807"
                     /db_xref="GeneID:933661"
     gene            1732263..1732451
                     /locus_tag="spr1766"
                     /db_xref="GeneID:933653"
     CDS             1732263..1732451
                     /locus_tag="spr1766"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359358.1"
                     /db_xref="GI:15903808"
                     /db_xref="GeneID:933653"
     gene            1732567..1735557
                     /gene="cylM"
                     /locus_tag="spr1767"
                     /db_xref="GeneID:933659"
     CDS             1732567..1735557
                     /gene="cylM"
                     /locus_tag="spr1767"
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin formation protein"
                     /protein_id="NP_359359.1"
                     /db_xref="GI:15903809"
                     /db_xref="GeneID:933659"
     gene            1735907..1736611
                     /locus_tag="spr1768"
                     /db_xref="GeneID:933658"
     CDS             1735907..1736611
                     /locus_tag="spr1768"
                     /note="Related to Trp repressor binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359360.1"
                     /db_xref="GI:15903810"
                     /db_xref="GeneID:933658"
     gene            1736592..1737521
                     /locus_tag="spr1769"
                     /db_xref="GeneID:933650"
     CDS             1736592..1737521
                     /locus_tag="spr1769"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359361.1"
                     /db_xref="GI:15903811"
                     /db_xref="GeneID:933650"
     gene            1737518..1739626
                     /gene="clyB"
                     /locus_tag="spr1770"
                     /db_xref="GeneID:933656"
     CDS             1737518..1739626
                     /gene="clyB"
                     /locus_tag="spr1770"
                     /codon_start=1
                     /transl_table=11
                     /product="toxin secretion ABC transporter
                     ATP-binding/permease"
                     /protein_id="NP_359362.1"
                     /db_xref="GI:15903812"
                     /db_xref="GeneID:933656"
     gene            1739650..1741389
                     /gene="nisP"
                     /locus_tag="spr1771"
                     /db_xref="GeneID:933654"
     CDS             1739650..1741389
                     /gene="nisP"
                     /locus_tag="spr1771"
                     /EC_number="3.4.21.-"
                     /codon_start=1
                     /transl_table=11
                     /product="subtilisin-like serine protease"
                     /protein_id="NP_359363.1"
                     /db_xref="GI:15903813"
                     /db_xref="GeneID:933654"
     gene            1741440..1742207
                     /locus_tag="spr1772"
                     /db_xref="GeneID:933646"
     CDS             1741440..1742207
                     /locus_tag="spr1772"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359364.1"
                     /db_xref="GI:15903814"
                     /db_xref="GeneID:933646"
     gene            1742209..1742841
                     /gene="ABC-NBD"
                     /locus_tag="spr1773"
                     /db_xref="GeneID:933652"
     CDS             1742209..1742841
                     /gene="ABC-NBD"
                     /locus_tag="spr1773"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359365.1"
                     /db_xref="GI:15903815"
                     /db_xref="GeneID:933652"
     gene            1742999..1743277
                     /locus_tag="spr1774"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933651"
     gene            complement(1743787..1744200)
                     /gene="ndk"
                     /locus_tag="spr1775"
                     /db_xref="GeneID:933643"
     CDS             complement(1743787..1744200)
                     /gene="ndk"
                     /locus_tag="spr1775"
                     /EC_number="2.7.4.6"
                     /note="catalyzes the formation of nucleoside triphosphate
                     from ATP and nucleoside diphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase"
                     /protein_id="NP_359367.1"
                     /db_xref="GI:15903817"
                     /db_xref="GeneID:933643"
     gene            complement(1744311..1747988)
                     /gene="rpoC"
                     /locus_tag="spr1776"
                     /db_xref="GeneID:933649"
     CDS             complement(1744311..1747988)
                     /gene="rpoC"
                     /locus_tag="spr1776"
                     /EC_number="2.7.7.6"
                     /note="DNA-dependent RNA polymerase catalyzes the
                     transcription of DNA into RNA using the four
                     ribonucleoside triphosphates as substrates. Subunit beta'
                     binds to sigma factor allowing it to bind to the -10
                     region of the promoter"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="NP_359368.1"
                     /db_xref="GI:15903818"
                     /db_xref="GeneID:933649"
     gene            complement(1748021..1751671)
                     /gene="rpoB"
                     /locus_tag="spr1777"
                     /db_xref="GeneID:933647"
     CDS             complement(1748021..1751671)
                     /gene="rpoB"
                     /locus_tag="spr1777"
                     /EC_number="2.7.7.6"
                     /note="DNA-dependent RNA polymerase catalyzes the
                     transcription of DNA into RNA using the four
                     ribonucleoside triphosphates as substrates; beta subunit
                     is part of the catalytic core which binds with a sigma
                     factor to produce the holoenzyme"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="NP_359369.1"
                     /db_xref="GI:15903819"
                     /db_xref="GeneID:933647"
     gene            1752048..1752118
                     /gene="tRNA-Cys"
                     /locus_tag="sprt31"
                     /db_xref="GeneID:933640"
     tRNA            1752048..1752118
                     /gene="tRNA-Cys"
                     /locus_tag="sprt31"
                     /product="tRNA-Cys"
                     /db_xref="GeneID:933640"
     gene            complement(1752316..1753647)
                     /gene="hlyX"
                     /locus_tag="spr1778"
                     /db_xref="GeneID:933644"
     CDS             complement(1752316..1753647)
                     /gene="hlyX"
                     /locus_tag="spr1778"
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="NP_359370.1"
                     /db_xref="GI:15903820"
                     /db_xref="GeneID:933644"
     gene            complement(1753876..1754700)
                     /gene="endA"
                     /locus_tag="spr1779"
                     /db_xref="GeneID:933636"
     CDS             complement(1753876..1754700)
                     /gene="endA"
                     /locus_tag="spr1779"
                     /EC_number="3.1.30.-"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease"
                     /protein_id="NP_359371.1"
                     /db_xref="GI:15903821"
                     /db_xref="GeneID:933636"
     gene            complement(1754739..1754945)
                     /gene="epuA"
                     /locus_tag="spr1780"
                     /db_xref="GeneID:933642"
     CDS             complement(1754739..1754945)
                     /gene="epuA"
                     /locus_tag="spr1780"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359372.1"
                     /db_xref="GI:15903822"
                     /db_xref="GeneID:933642"
     gene            complement(1754920..1756203)
                     /gene="murA"
                     /locus_tag="spr1781"
                     /db_xref="GeneID:933641"
     CDS             complement(1754920..1756203)
                     /gene="murA"
                     /locus_tag="spr1781"
                     /EC_number="2.5.1.7"
                     /note="adds enolpyruvyl to UDP-N-acetylglucosamine as a
                     component of cell wall formation; gram-positive bacteria
                     have 2 copies of MurA which are active"
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="NP_359373.1"
                     /db_xref="GI:15903823"
                     /db_xref="GeneID:933641"
     gene            complement(1756227..1756457)
                     /locus_tag="spr1781a"
                     /db_xref="GeneID:17374512"
     CDS             complement(1756227..1756457)
                     /locus_tag="spr1781a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719807.1"
                     /db_xref="GI:555247353"
                     /db_xref="GeneID:17374512"
     gene            complement(1756515..1757552)
                     /locus_tag="spr1782"
                     /db_xref="GeneID:933633"
     CDS             complement(1756515..1757552)
                     /locus_tag="spr1782"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359374.1"
                     /db_xref="GI:15903824"
                     /db_xref="GeneID:933633"
     gene            complement(1757536..1758024)
                     /gene="coaD"
                     /locus_tag="spr1783"
                     /db_xref="GeneID:933639"
     CDS             complement(1757536..1758024)
                     /gene="coaD"
                     /locus_tag="spr1783"
                     /EC_number="2.7.7.3"
                     /note="Catalyzes the conversion of ATP and pantetheine
                     4'-phosphate to diphosphate and 3'-dephospho-coA"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantetheine adenylyltransferase"
                     /protein_id="NP_359375.1"
                     /db_xref="GI:15903825"
                     /db_xref="GeneID:933639"
     gene            complement(1758014..1758553)
                     /locus_tag="spr1784"
                     /db_xref="GeneID:933637"
     CDS             complement(1758014..1758553)
                     /locus_tag="spr1784"
                     /note="Probable methylase"
                     /codon_start=1
                     /transl_table=11
                     /product="type II DNA modification methyltransferase"
                     /protein_id="NP_359376.1"
                     /db_xref="GI:15903826"
                     /db_xref="GeneID:933637"
     gene            complement(1758618..1759616)
                     /gene="asnA"
                     /locus_tag="spr1785"
                     /db_xref="GeneID:933629"
     CDS             complement(1758618..1759616)
                     /gene="asnA"
                     /locus_tag="spr1785"
                     /EC_number="6.3.1.1"
                     /note="catalyzes the formation of asparagine from
                     aspartate and ammonia"
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthetase AsnA"
                     /protein_id="NP_359377.1"
                     /db_xref="GI:15903827"
                     /db_xref="GeneID:933629"
     gene            complement(1759722..1760429)
                     /locus_tag="spr1787"
                     /db_xref="GeneID:933634"
     CDS             complement(1759722..1760429)
                     /locus_tag="spr1787"
                     /note="transmembrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359379.1"
                     /db_xref="GI:15903829"
                     /db_xref="GeneID:933634"
     gene            complement(1760461..1761219)
                     /gene="yjfA"
                     /locus_tag="spr1788"
                     /db_xref="GeneID:933626"
     CDS             complement(1760461..1761219)
                     /gene="yjfA"
                     /locus_tag="spr1788"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA/tRNA methylase"
                     /protein_id="NP_359380.1"
                     /db_xref="GI:15903830"
                     /db_xref="GeneID:933626"
     gene            1761235..1761513
                     /gene="acyP"
                     /locus_tag="spr1789"
                     /db_xref="GeneID:933631"
     CDS             1761235..1761513
                     /gene="acyP"
                     /locus_tag="spr1789"
                     /EC_number="3.6.1.7"
                     /note="catalyzes the hydrolysis of acylphosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="NP_359381.1"
                     /db_xref="GI:15903831"
                     /db_xref="GeneID:933631"
     gene            1761591..1762517
                     /locus_tag="spr1790"
                     /db_xref="GeneID:933632"
     CDS             1761591..1762517
                     /locus_tag="spr1790"
                     /note="involved in biogenesis of membrane proteins;
                     Firmicutes specific proteins are shorter than other
                     bacterial counterparts and have a signal peptide and lipid
                     attachment site"
                     /codon_start=1
                     /transl_table=11
                     /product="OxaA-like protein"
                     /protein_id="NP_359382.1"
                     /db_xref="GI:15903832"
                     /db_xref="GeneID:933632"
     gene            complement(1762592..1763386)
                     /gene="pflC"
                     /locus_tag="spr1791"
                     /db_xref="GeneID:933619"
     CDS             complement(1762592..1763386)
                     /gene="pflC"
                     /locus_tag="spr1791"
                     /EC_number="1.97.1.4"
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate-formate lyase activating enzyme"
                     /protein_id="NP_359383.1"
                     /db_xref="GI:15903833"
                     /db_xref="GeneID:933619"
     gene            complement(1763512..1764762)
                     /gene="lysA"
                     /locus_tag="spr1792"
                     /db_xref="GeneID:933628"
     CDS             complement(1763512..1764762)
                     /gene="lysA"
                     /locus_tag="spr1792"
                     /EC_number="4.1.1.20"
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="NP_359384.1"
                     /db_xref="GI:15903834"
                     /db_xref="GeneID:933628"
     gene            complement(1764829..1765656)
                     /gene="purR"
                     /locus_tag="spr1793"
                     /db_xref="GeneID:933627"
     CDS             complement(1764829..1765656)
                     /gene="purR"
                     /locus_tag="spr1793"
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="NP_359385.1"
                     /db_xref="GI:15903835"
                     /db_xref="GeneID:933627"
     repeat_region   complement(1765720..1765755)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_b"
     gene            complement(1765923..1766927)
                     /gene="cbf1"
                     /locus_tag="spr1794"
                     /db_xref="GeneID:933622"
     CDS             complement(1765923..1766927)
                     /gene="cbf1"
                     /locus_tag="spr1794"
                     /codon_start=1
                     /transl_table=11
                     /product="cmp-binding-factor 1"
                     /protein_id="NP_359386.1"
                     /db_xref="GI:15903836"
                     /db_xref="GeneID:933622"
     gene            complement(1766854..1768152)
                     /locus_tag="spr1795"
                     /db_xref="GeneID:933621"
     CDS             complement(1766854..1768152)
                     /locus_tag="spr1795"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359387.1"
                     /db_xref="GI:15903837"
                     /db_xref="GeneID:933621"
     gene            complement(1768112..1768795)
                     /locus_tag="spr1796"
                     /db_xref="GeneID:933613"
     CDS             complement(1768112..1768795)
                     /locus_tag="spr1796"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359388.1"
                     /db_xref="GI:15903838"
                     /db_xref="GeneID:933613"
     gene            complement(1768737..1769393)
                     /gene="rpe"
                     /locus_tag="spr1797"
                     /db_xref="GeneID:933617"
     CDS             complement(1768737..1769393)
                     /gene="rpe"
                     /locus_tag="spr1797"
                     /EC_number="5.1.3.1"
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="NP_359389.1"
                     /db_xref="GI:15903839"
                     /db_xref="GeneID:933617"
     gene            complement(1769404..1770282)
                     /locus_tag="spr1798"
                     /db_xref="GeneID:933616"
     CDS             complement(1769404..1770282)
                     /locus_tag="spr1798"
                     /note="EngC; RsgA; CpgA; circularly permuted GTPase;
                     ribosome small subunit-dependent GTPase A; has the pattern
                     G4-G1-G3 as opposed to other GTPases; interacts strongly
                     with 30S ribosome which stimulates GTPase activity"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated GTPase"
                     /protein_id="NP_359390.1"
                     /db_xref="GI:15903840"
                     /db_xref="GeneID:933616"
     gene            complement(1770284..1771156)
                     /gene="ksgA"
                     /locus_tag="spr1799"
                     /db_xref="GeneID:933610"
     CDS             complement(1770284..1771156)
                     /gene="ksgA"
                     /locus_tag="spr1799"
                     /EC_number="2.1.1.-"
                     /note="catalyzes the transfer of a total of four methyl
                     groups from S-adenosyl-l-methionine (S-AdoMet) to two
                     adjacent adenosine bases A1518 and A1519 in 16S rRNA;
                     mutations in ksgA causes resistance to the translation
                     initiation inhibitor kasugamycin"
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyladenosine transferase"
                     /protein_id="NP_359391.1"
                     /db_xref="GI:15903841"
                     /db_xref="GeneID:933610"
     gene            complement(1771287..1771601)
                     /locus_tag="spr1800"
                     /db_xref="GeneID:933615"
     CDS             complement(1771287..1771601)
                     /locus_tag="spr1800"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359392.1"
                     /db_xref="GI:15903842"
                     /db_xref="GeneID:933615"
     gene            complement(1771588..1772229)
                     /gene="ABC-NBD"
                     /locus_tag="spr1801"
                     /db_xref="GeneID:933614"
     CDS             complement(1771588..1772229)
                     /gene="ABC-NBD"
                     /locus_tag="spr1801"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359393.1"
                     /db_xref="GI:15903843"
                     /db_xref="GeneID:933614"
     gene            complement(1772231..1774273)
                     /locus_tag="spr1802"
                     /db_xref="GeneID:933608"
     CDS             complement(1772231..1774273)
                     /locus_tag="spr1802"
                     /note="immunity protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359394.1"
                     /db_xref="GI:15903844"
                     /db_xref="GeneID:933608"
     gene            complement(1774530..1775429)
                     /gene="plcR"
                     /locus_tag="spr1803"
                     /db_xref="GeneID:933612"
     CDS             complement(1774530..1775429)
                     /gene="plcR"
                     /locus_tag="spr1803"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PlcR"
                     /protein_id="NP_359395.1"
                     /db_xref="GI:15903845"
                     /db_xref="GeneID:933612"
     gene            complement(1775501..1776061)
                     /locus_tag="spr1804"
                     /db_xref="GeneID:933611"
     CDS             complement(1775501..1776061)
                     /locus_tag="spr1804"
                     /note="Primase-related protein"
                     /codon_start=1
                     /transl_table=11
                     /product="primase-related protein"
                     /protein_id="NP_359396.1"
                     /db_xref="GI:15903846"
                     /db_xref="GeneID:933611"
     gene            complement(1776061..1776834)
                     /locus_tag="spr1805"
                     /db_xref="GeneID:933604"
     CDS             complement(1776061..1776834)
                     /locus_tag="spr1805"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359397.1"
                     /db_xref="GI:15903847"
                     /db_xref="GeneID:933604"
     gene            complement(1777140..1777805)
                     /locus_tag="spr1806"
                     /db_xref="GeneID:933609"
     CDS             complement(1777140..1777805)
                     /locus_tag="spr1806"
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall surface anchor family protein"
                     /protein_id="NP_359398.1"
                     /db_xref="GI:15903848"
                     /db_xref="GeneID:933609"
     repeat_region   complement(1777858..1777964)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1778068..1778202)
                     /gene="rpmH"
                     /locus_tag="spr1807"
                     /db_xref="GeneID:933601"
     CDS             complement(1778068..1778202)
                     /gene="rpmH"
                     /locus_tag="spr1807"
                     /note="in Escherichia coli transcription of this gene is
                     enhanced by polyamines"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="NP_359399.1"
                     /db_xref="GI:15903849"
                     /db_xref="GeneID:933601"
     gene            complement(1778347..1779561)
                     /gene="aspC"
                     /locus_tag="spr1808"
                     /db_xref="GeneID:933607"
     CDS             complement(1778347..1779561)
                     /gene="aspC"
                     /locus_tag="spr1808"
                     /EC_number="2.6.1.2"
                     /note="broad specificity; family IV; in Corynebacterium
                     glutamicum this protein can use glutamate,
                     2-aminobutyrate, and aspartate as amino donors and
                     pyruvate as the acceptor"
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="NP_359400.1"
                     /db_xref="GI:15903850"
                     /db_xref="GeneID:933607"
     gene            complement(1779717..1780025)
                     /locus_tag="spr1809"
                     /db_xref="GeneID:933606"
     CDS             complement(1779717..1780025)
                     /locus_tag="spr1809"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359401.1"
                     /db_xref="GI:15903851"
                     /db_xref="GeneID:933606"
     gene            1780109..1780624
                     /locus_tag="spr1810"
                     /db_xref="GeneID:933599"
     CDS             1780109..1780624
                     /locus_tag="spr1810"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359402.1"
                     /db_xref="GI:15903852"
                     /db_xref="GeneID:933599"
     gene            complement(1780659..1782077)
                     /locus_tag="spr1811"
                     /db_xref="GeneID:933603"
     CDS             complement(1780659..1782077)
                     /locus_tag="spr1811"
                     /codon_start=1
                     /transl_table=11
                     /product="Cof family protein"
                     /protein_id="NP_359403.1"
                     /db_xref="GI:15903853"
                     /db_xref="GeneID:933603"
     gene            1782113..1783075
                     /gene="ansB"
                     /locus_tag="spr1812"
                     /db_xref="GeneID:933602"
     CDS             1782113..1783075
                     /gene="ansB"
                     /locus_tag="spr1812"
                     /EC_number="3.5.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase"
                     /protein_id="NP_359404.1"
                     /db_xref="GI:15903854"
                     /db_xref="GeneID:933602"
     gene            complement(1783072..1783263)
                     /locus_tag="spr1812a"
                     /db_xref="GeneID:17374513"
     CDS             complement(1783072..1783263)
                     /locus_tag="spr1812a"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="YP_008719808.1"
                     /db_xref="GI:555247354"
                     /db_xref="GeneID:17374513"
     repeat_region   1783129..1783212
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_bb"
     gene            complement(1783327..1784367)
                     /gene="ccpA"
                     /locus_tag="spr1813"
                     /db_xref="GeneID:933600"
     CDS             complement(1783327..1784367)
                     /gene="ccpA"
                     /locus_tag="spr1813"
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="NP_359405.1"
                     /db_xref="GI:15903855"
                     /db_xref="GeneID:933600"
     repeat_region   complement(1784590..1784696)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1784762..1785361)
                     /gene="rr11"
                     /locus_tag="spr1814"
                     /db_xref="GeneID:933595"
     CDS             complement(1784762..1785361)
                     /gene="rr11"
                     /locus_tag="spr1814"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="NP_359406.1"
                     /db_xref="GI:15903856"
                     /db_xref="GeneID:933595"
     gene            complement(1785363..1786460)
                     /gene="hk11"
                     /locus_tag="spr1815"
                     /db_xref="GeneID:933598"
     CDS             complement(1785363..1786460)
                     /gene="hk11"
                     /locus_tag="spr1815"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="NP_359407.1"
                     /db_xref="GI:15903857"
                     /db_xref="GeneID:933598"
     gene            complement(1786460..1787227)
                     /locus_tag="spr1816"
                     /db_xref="GeneID:933597"
     CDS             complement(1786460..1787227)
                     /locus_tag="spr1816"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359408.1"
                     /db_xref="GI:15903858"
                     /db_xref="GeneID:933597"
     gene            complement(1787199..1788083)
                     /gene="ABC-NBD"
                     /locus_tag="spr1817"
                     /db_xref="GeneID:933591"
     CDS             complement(1787199..1788083)
                     /gene="ABC-NBD"
                     /locus_tag="spr1817"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359409.1"
                     /db_xref="GI:15903859"
                     /db_xref="GeneID:933591"
     gene            complement(1788261..1788467)
                     /locus_tag="spr1818"
                     /db_xref="GeneID:933596"
     CDS             complement(1788261..1788467)
                     /locus_tag="spr1818"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359410.1"
                     /db_xref="GI:15903860"
                     /db_xref="GeneID:933596"
     repeat_region   1788705..1788803
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b1"
     gene            complement(1789055..1789128)
                     /gene="tRNA-Pro2"
                     /locus_tag="sprt32"
                     /db_xref="GeneID:933589"
     tRNA            complement(1789055..1789128)
                     /gene="tRNA-Pro2"
                     /locus_tag="sprt32"
                     /product="tRNA-Pro"
                     /db_xref="GeneID:933589"
     gene            complement(1789144..1789217)
                     /gene="tRNA-Arg4"
                     /locus_tag="sprt33"
                     /db_xref="GeneID:933592"
     tRNA            complement(1789144..1789217)
                     /gene="tRNA-Arg4"
                     /locus_tag="sprt33"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:933592"
     gene            complement(1789227..1789312)
                     /gene="tRNA-Leu4"
                     /locus_tag="sprt34"
                     /db_xref="GeneID:933590"
     tRNA            complement(1789227..1789312)
                     /gene="tRNA-Leu4"
                     /locus_tag="sprt34"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:933590"
     gene            complement(1789320..1789391)
                     /gene="tRNA-Gly3"
                     /locus_tag="sprt35"
                     /db_xref="GeneID:933585"
     tRNA            complement(1789320..1789391)
                     /gene="tRNA-Gly3"
                     /locus_tag="sprt35"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:933585"
     gene            complement(1789414..1789486)
                     /gene="tRNA-Thr3"
                     /locus_tag="sprt36"
                     /db_xref="GeneID:933587"
     tRNA            complement(1789414..1789486)
                     /gene="tRNA-Thr3"
                     /locus_tag="sprt36"
                     /product="tRNA-Thr"
                     /db_xref="GeneID:933587"
     gene            complement(1789505..1789586)
                     /gene="tRNA-Leu5"
                     /locus_tag="sprt37"
                     /db_xref="GeneID:933586"
     tRNA            complement(1789505..1789586)
                     /gene="tRNA-Leu5"
                     /locus_tag="sprt37"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:933586"
     gene            complement(1789592..1789664)
                     /gene="tRNA-Lys3"
                     /locus_tag="sprt38"
                     /db_xref="GeneID:933579"
     tRNA            complement(1789592..1789664)
                     /gene="tRNA-Lys3"
                     /locus_tag="sprt38"
                     /product="tRNA-Lys"
                     /db_xref="GeneID:933579"
     gene            complement(1789689..1789761)
                     /gene="tRNA-Asp2"
                     /locus_tag="sprt39"
                     /db_xref="GeneID:933583"
     tRNA            complement(1789689..1789761)
                     /gene="tRNA-Asp2"
                     /locus_tag="sprt39"
                     /product="tRNA-Asp"
                     /db_xref="GeneID:933583"
     gene            complement(1789764..1789836)
                     /gene="tRNA-Val2"
                     /locus_tag="sprt40"
                     /db_xref="GeneID:933581"
     tRNA            complement(1789764..1789836)
                     /gene="tRNA-Val2"
                     /locus_tag="sprt40"
                     /product="tRNA-Val"
                     /db_xref="GeneID:933581"
     gene            complement(1789841..1789955)
                     /gene="rRNA_5S-3"
                     /locus_tag="sprr07"
                     /db_xref="GeneID:933575"
     rRNA            complement(1789841..1789955)
                     /gene="rRNA_5S-3"
                     /locus_tag="sprr07"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:933575"
     gene            complement(1790033..1792934)
                     /gene="rRNA_23S-3"
                     /locus_tag="sprr08"
                     /db_xref="GeneID:933578"
     rRNA            complement(1790033..1792934)
                     /gene="rRNA_23S-3"
                     /locus_tag="sprr08"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:933578"
     gene            complement(1793059..1793131)
                     /gene="tRNA-Ala3"
                     /locus_tag="sprt41"
                     /db_xref="GeneID:933576"
     tRNA            complement(1793059..1793131)
                     /gene="tRNA-Ala3"
                     /locus_tag="sprt41"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:933576"
     gene            complement(1793205..1794718)
                     /gene="rRNA_16S-3"
                     /locus_tag="sprr09"
                     /db_xref="GeneID:933571"
     rRNA            complement(1793205..1794718)
                     /gene="rRNA_16S-3"
                     /locus_tag="sprr09"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:933571"
     gene            complement(1794981..1795052)
                     /gene="tRNA-Glu3"
                     /locus_tag="sprt42"
                     /db_xref="GeneID:933574"
     tRNA            complement(1794981..1795052)
                     /gene="tRNA-Glu3"
                     /locus_tag="sprt42"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:933574"
     gene            complement(1795146..1795625)
                     /gene="comX2"
                     /locus_tag="spr1819"
                     /db_xref="GeneID:933573"
     CDS             complement(1795146..1795625)
                     /gene="comX2"
                     /locus_tag="spr1819"
                     /note="sigma factor"
                     /codon_start=1
                     /transl_table=11
                     /product="competence-specific global transcription
                     modulator"
                     /protein_id="NP_359411.1"
                     /db_xref="GI:15903861"
                     /db_xref="GeneID:933573"
     gene            complement(1795747..1796298)
                     /gene="nusG"
                     /locus_tag="spr1820"
                     /db_xref="GeneID:933572"
     CDS             complement(1795747..1796298)
                     /gene="nusG"
                     /locus_tag="spr1820"
                     /note="Modulates Rho-dependent transcription termination"
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination protein NusG"
                     /protein_id="NP_359412.1"
                     /db_xref="GI:15903862"
                     /db_xref="GeneID:933572"
     gene            complement(1796338..1796514)
                     /gene="secE"
                     /locus_tag="spr1821"
                     /db_xref="GeneID:933566"
     CDS             complement(1796338..1796514)
                     /gene="secE"
                     /locus_tag="spr1821"
                     /note="forms a complex with SecY and SecG; SecYEG forms a
                     protein-conducting channel to which secA binds and
                     translocates targeted polypeptides across the cytoplasmic
                     membrane, a process driven by ATP and a proton-motive
                     force"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="NP_359413.1"
                     /db_xref="GI:15903863"
                     /db_xref="GeneID:933566"
     gene            complement(1796524..1796676)
                     /gene="rpmG"
                     /locus_tag="spr1822"
                     /db_xref="GeneID:933570"
     CDS             complement(1796524..1796676)
                     /gene="rpmG"
                     /locus_tag="spr1822"
                     /note="in Escherichia coli BM108, a mutation that results
                     in lack of L33 synthesis had no effect on ribosome
                     synthesis or function; there are paralogous genes in
                     several bacterial genomes, and a CXXC motif for zinc
                     binding and an upstream regulation region of the paralog
                     lacking this motif that are regulated by zinc similar to
                     other ribosomal proteins like L31; the proteins in this
                     group have the CXXC motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="NP_359414.1"
                     /db_xref="GI:15903864"
                     /db_xref="GeneID:933570"
     gene            complement(1796729..1798924)
                     /gene="pbp2a"
                     /locus_tag="spr1823"
                     /db_xref="GeneID:933569"
     CDS             complement(1796729..1798924)
                     /gene="pbp2a"
                     /locus_tag="spr1823"
                     /EC_number="2.3.2.-"
                     /EC_number="2.4.1.129"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2A"
                     /protein_id="NP_359415.1"
                     /db_xref="GI:15903865"
                     /db_xref="GeneID:933569"
     gene            1799011..1799886
                     /gene="rluD"
                     /locus_tag="spr1824"
                     /db_xref="GeneID:933563"
     CDS             1799011..1799886
                     /gene="rluD"
                     /locus_tag="spr1824"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal large subunit pseudouridine synthase
                     D"
                     /protein_id="NP_359416.1"
                     /db_xref="GI:15903866"
                     /db_xref="GeneID:933563"
     gene            complement(1799954..1801033)
                     /gene="gapA"
                     /locus_tag="spr1825"
                     /db_xref="GeneID:933568"
     CDS             complement(1799954..1801033)
                     /gene="gapA"
                     /locus_tag="spr1825"
                     /EC_number="1.2.1.12"
                     /note="catalyzes the formation of 3-phospho-D-glyceroyl
                     phosphate from D-glyceraldehyde 3-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="NP_359417.1"
                     /db_xref="GI:15903867"
                     /db_xref="GeneID:933568"
     gene            complement(1801138..1802118)
                     /locus_tag="spr1826"
                     /db_xref="GeneID:933567"
     CDS             complement(1801138..1802118)
                     /locus_tag="spr1826"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359418.1"
                     /db_xref="GI:15903868"
                     /db_xref="GeneID:933567"
     gene            complement(1802664..1803011)
                     /gene="transposase_A"
                     /locus_tag="spr1828"
                     /db_xref="GeneID:933565"
     CDS             complement(1802664..1803011)
                     /gene="transposase_A"
                     /locus_tag="spr1828"
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="NP_359420.1"
                     /db_xref="GI:15903870"
                     /db_xref="GeneID:933565"
     gene            complement(1803124..1804023)
                     /gene="nadC"
                     /locus_tag="spr1829"
                     /db_xref="GeneID:933564"
     CDS             complement(1803124..1804023)
                     /gene="nadC"
                     /locus_tag="spr1829"
                     /EC_number="2.4.2.19"
                     /note="catalyzes the formation of
                     pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose
                     1-diphosphate from nictinate D-ribonucleotide"
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide pyrophosphorylase"
                     /protein_id="NP_359421.1"
                     /db_xref="GI:15903871"
                     /db_xref="GeneID:933564"
     gene            1804233..1805543
                     /locus_tag="spr1830"
                     /db_xref="GeneID:933778"
     CDS             1804233..1805543
                     /locus_tag="spr1830"
                     /note="integral membrane protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359422.1"
                     /db_xref="GI:15903872"
                     /db_xref="GeneID:933778"
     repeat_region   complement(1805802..1805908)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1805909..1806103)
                     /locus_tag="spr1831"
                     /db_xref="GeneID:933562"
     CDS             complement(1805909..1806103)
                     /locus_tag="spr1831"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359423.1"
                     /db_xref="GI:15903873"
                     /db_xref="GeneID:933562"
     gene            complement(1806563..1807291)
                     /locus_tag="spr1832"
                     /db_xref="GeneID:933801"
     CDS             complement(1806563..1807291)
                     /locus_tag="spr1832"
                     /note="transcription regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359424.1"
                     /db_xref="GI:15903874"
                     /db_xref="GeneID:933801"
     gene            1807407..1808858
                     /gene="bgl2"
                     /locus_tag="spr1833"
                     /db_xref="GeneID:933560"
     CDS             1807407..1808858
                     /gene="bgl2"
                     /locus_tag="spr1833"
                     /EC_number="3.2.1.21"
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase"
                     /protein_id="NP_359425.1"
                     /db_xref="GI:15903875"
                     /db_xref="GeneID:933560"
     gene            1808876..1810171
                     /gene="ptcC"
                     /locus_tag="spr1834"
                     /db_xref="GeneID:933775"
     CDS             1808876..1810171
                     /gene="ptcC"
                     /locus_tag="spr1834"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_359426.1"
                     /db_xref="GI:15903876"
                     /db_xref="GeneID:933775"
     gene            1810176..1810484
                     /gene="ptcB"
                     /locus_tag="spr1835"
                     /db_xref="GeneID:933815"
     CDS             1810176..1810484
                     /gene="ptcB"
                     /locus_tag="spr1835"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_359427.1"
                     /db_xref="GI:15903877"
                     /db_xref="GeneID:933815"
     gene            1810463..1810789
                     /gene="ptcA"
                     /locus_tag="spr1836"
                     /db_xref="GeneID:933795"
     CDS             1810463..1810789
                     /gene="ptcA"
                     /locus_tag="spr1836"
                     /EC_number="2.7.1.69"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_359428.1"
                     /db_xref="GI:15903878"
                     /db_xref="GeneID:933795"
     repeat_region   complement(1811305..1811403)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_b2"
     repeat_region   complement(1811416..1811522)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1811697..1814369)
                     /gene="adhE"
                     /locus_tag="spr1837"
                     /db_xref="GeneID:933809"
     CDS             complement(1811697..1814369)
                     /gene="adhE"
                     /locus_tag="spr1837"
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="NP_359429.1"
                     /db_xref="GI:15903879"
                     /db_xref="GeneID:933809"
     gene            complement(1814648..1815058)
                     /locus_tag="spr1838"
                     /db_xref="GeneID:933811"
     CDS             complement(1814648..1815058)
                     /locus_tag="spr1838"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359430.1"
                     /db_xref="GI:15903880"
                     /db_xref="GeneID:933811"
     gene            complement(1815060..1815488)
                     /locus_tag="spr1839"
                     /db_xref="GeneID:933856"
     CDS             complement(1815060..1815488)
                     /locus_tag="spr1839"
                     /note="protein-tyrosine-phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotyrosine protein phosphatase"
                     /protein_id="NP_359431.1"
                     /db_xref="GI:15903881"
                     /db_xref="GeneID:933856"
     gene            complement(1815535..1815834)
                     /gene="yajC"
                     /locus_tag="spr1840"
                     /db_xref="GeneID:933824"
     CDS             complement(1815535..1815834)
                     /gene="yajC"
                     /locus_tag="spr1840"
                     /note="member of preprotein translocase; forms a
                     heterotrimer with SecD and SecF; links the
                     SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG
                     complex"
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="NP_359432.1"
                     /db_xref="GI:15903882"
                     /db_xref="GeneID:933824"
     gene            complement(1815951..1817927)
                     /gene="tktA"
                     /locus_tag="spr1841"
                     /db_xref="GeneID:933829"
     CDS             complement(1815951..1817927)
                     /gene="tktA"
                     /locus_tag="spr1841"
                     /EC_number="2.2.1.1"
                     /note="catalyzes the formation of ribose 5-phosphate and
                     xylulose 5-phosphate from sedoheptulose 7-phosphate and
                     glyceraldehyde 3-phosphate; can transfer ketol groups
                     between several groups; in Escherichia coli there are two
                     tkt genes, tktA expressed during exponential growth and
                     the tktB during stationary phase"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="NP_359433.1"
                     /db_xref="GI:15903883"
                     /db_xref="GeneID:933829"
     gene            complement(1818041..1819132)
                     /locus_tag="spr1842"
                     /db_xref="GeneID:933878"
     CDS             complement(1818041..1819132)
                     /locus_tag="spr1842"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="NP_359434.1"
                     /db_xref="GI:15903884"
                     /db_xref="GeneID:933878"
     gene            complement(1819244..1820917)
                     /locus_tag="spr1843"
                     /db_xref="GeneID:933847"
     CDS             complement(1819244..1820917)
                     /locus_tag="spr1843"
                     /note="transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359435.1"
                     /db_xref="GI:15903885"
                     /db_xref="GeneID:933847"
     gene            complement(1821096..1821800)
                     /gene="araD"
                     /locus_tag="spr1844"
                     /db_xref="GeneID:933851"
     CDS             complement(1821096..1821800)
                     /gene="araD"
                     /locus_tag="spr1844"
                     /EC_number="5.1.3.4"
                     /note="catalyzes the formation of D-xylulose 5-phosphate
                     from L-ribulose 5-phosphate in the L-arabinose and
                     L-ascorbate degradation pathways"
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="NP_359436.1"
                     /db_xref="GI:15903886"
                     /db_xref="GeneID:933851"
     gene            complement(1821802..1822665)
                     /gene="sga"
                     /locus_tag="spr1845"
                     /db_xref="GeneID:933901"
     CDS             complement(1821802..1822665)
                     /gene="sga"
                     /locus_tag="spr1845"
                     /EC_number="5.-.-.-"
                     /note="L-xylulose 5-phosphate 3-epimerase activity not yet
                     demonstrated; may be involved in the utilization of
                     2,3-diketo-L-gulonate"
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulose 5-phosphate 3-epimerase"
                     /protein_id="NP_359437.1"
                     /db_xref="GI:15903887"
                     /db_xref="GeneID:933901"
     gene            complement(1822669..1823334)
                     /gene="ulaD"
                     /locus_tag="spr1846"
                     /db_xref="GeneID:933867"
     CDS             complement(1822669..1823334)
                     /gene="ulaD"
                     /locus_tag="spr1846"
                     /EC_number="4.1.1.85"
                     /note="catalyzes the formation of L-xylulose-5-phosphate
                     from 3-keto-L-gulonate-6-phosphate in anaerobic
                     L-ascorbate utilization"
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase"
                     /protein_id="NP_359438.2"
                     /db_xref="GI:161410737"
                     /db_xref="GeneID:933867"
     gene            complement(1823351..1823836)
                     /gene="PTS-EII"
                     /locus_tag="spr1847"
                     /db_xref="GeneID:933871"
     CDS             complement(1823351..1823836)
                     /gene="PTS-EII"
                     /locus_tag="spr1847"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_359439.1"
                     /db_xref="GI:15903889"
                     /db_xref="GeneID:933871"
     gene            complement(1823913..1824194)
                     /gene="PTS-EII"
                     /locus_tag="spr1848"
                     /db_xref="GeneID:933915"
     CDS             complement(1823913..1824194)
                     /gene="PTS-EII"
                     /locus_tag="spr1848"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_359440.1"
                     /db_xref="GI:15903890"
                     /db_xref="GeneID:933915"
     gene            complement(1824217..1825674)
                     /gene="ulaA"
                     /locus_tag="spr1849"
                     /gene_synonym="sgaT"
                     /db_xref="GeneID:933892"
     CDS             complement(1824217..1825674)
                     /gene="ulaA"
                     /locus_tag="spr1849"
                     /gene_synonym="sgaT"
                     /note="membrane component; functions with enzymes IIB
                     (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for
                     anaerobic utilization and uptake of L-ascorbate; sgaTBA
                     are regulated by yifQ as well as Crp and Fnr"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system ascorbate-specific transporter
                     subunit IIC"
                     /protein_id="NP_359441.2"
                     /db_xref="GI:161410736"
                     /db_xref="GeneID:933892"
     gene            complement(1825805..1826428)
                     /locus_tag="spr1850"
                     /db_xref="GeneID:933898"
     CDS             complement(1825805..1826428)
                     /locus_tag="spr1850"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359442.1"
                     /db_xref="GI:15903892"
                     /db_xref="GeneID:933898"
     gene            complement(1826479..1827465)
                     /locus_tag="spr1851"
                     /db_xref="GeneID:933938"
     CDS             complement(1826479..1827465)
                     /locus_tag="spr1851"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359443.1"
                     /db_xref="GI:15903893"
                     /db_xref="GeneID:933938"
     gene            complement(1827484..1828314)
                     /locus_tag="spr1852"
                     /db_xref="GeneID:933908"
     CDS             complement(1827484..1828314)
                     /locus_tag="spr1852"
                     /note="Similar to Bacillus subtilis SpoIIIJ"
                     /codon_start=1
                     /transl_table=11
                     /product="SpoIIIJ family protein"
                     /protein_id="NP_359444.1"
                     /db_xref="GI:15903894"
                     /db_xref="GeneID:933908"
     gene            complement(1828283..1828654)
                     /gene="rnpA"
                     /locus_tag="spr1853"
                     /db_xref="GeneID:933911"
     CDS             complement(1828283..1828654)
                     /gene="rnpA"
                     /locus_tag="spr1853"
                     /EC_number="3.1.26.5"
                     /note="protein component of RNaseP which catalyzes the
                     removal of the 5'-leader sequence from pre-tRNA to produce
                     the mature 5'terminus; this enzyme also cleaves other RNA
                     substrates"
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="NP_359445.1"
                     /db_xref="GI:15903895"
                     /db_xref="GeneID:933911"
     gene            complement(1828803..1829993)
                     /gene="ackA"
                     /locus_tag="spr1854"
                     /db_xref="GeneID:933975"
     CDS             complement(1828803..1829993)
                     /gene="ackA"
                     /locus_tag="spr1854"
                     /EC_number="2.7.2.1"
                     /note="AckA utilizes acetate and can acetylate CheY which
                     increases signal strength during flagellar rotation;
                     utilizes magnesium and ATP; also involved in conversion of
                     acetate to aceyl-CoA"
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="NP_359446.1"
                     /db_xref="GI:15903896"
                     /db_xref="GeneID:933975"
     gene            complement(1830044..1830997)
                     /locus_tag="spr1855"
                     /db_xref="GeneID:933926"
     CDS             complement(1830044..1830997)
                     /locus_tag="spr1855"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359447.1"
                     /db_xref="GI:15903897"
                     /db_xref="GeneID:933926"
     gene            complement(1831058..1831652)
                     /locus_tag="spr1856"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933929"
     gene            complement(1831789..1832202)
                     /locus_tag="spr1858"
                     /db_xref="GeneID:933961"
     CDS             complement(1831789..1832202)
                     /locus_tag="spr1858"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359450.1"
                     /db_xref="GI:15903900"
                     /db_xref="GeneID:933961"
     gene            complement(1832180..1832686)
                     /locus_tag="spr1859"
                     /db_xref="GeneID:933974"
     CDS             complement(1832180..1832686)
                     /locus_tag="spr1859"
                     /note="Competence induced; related to comYD"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359451.1"
                     /db_xref="GI:15903901"
                     /db_xref="GeneID:933974"
     gene            complement(1832869..1833351)
                     /gene="cglD"
                     /locus_tag="spr1861"
                     /db_xref="GeneID:933985"
     CDS             complement(1832869..1833351)
                     /gene="cglD"
                     /locus_tag="spr1861"
                     /note="Competence induced; comG-like protein D"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CglD"
                     /protein_id="NP_359452.1"
                     /db_xref="GI:15903902"
                     /db_xref="GeneID:933985"
     gene            complement(1833266..1833592)
                     /gene="cglC"
                     /locus_tag="spr1862"
                     /db_xref="GeneID:933977"
     CDS             complement(1833266..1833592)
                     /gene="cglC"
                     /locus_tag="spr1862"
                     /note="Competence induced; comG-like protein C"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CglC"
                     /protein_id="NP_359453.1"
                     /db_xref="GI:15903903"
                     /db_xref="GeneID:933977"
     gene            complement(1833594..1834685)
                     /gene="cglB"
                     /locus_tag="spr1863"
                     /db_xref="GeneID:933980"
     CDS             complement(1833594..1834685)
                     /gene="cglB"
                     /locus_tag="spr1863"
                     /note="Competence induced; comG-like protein B"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CglB"
                     /protein_id="NP_359454.1"
                     /db_xref="GI:15903904"
                     /db_xref="GeneID:933980"
     gene            complement(1834558..1835499)
                     /gene="cglA"
                     /locus_tag="spr1864"
                     /db_xref="GeneID:933989"
     CDS             complement(1834558..1835499)
                     /gene="cglA"
                     /locus_tag="spr1864"
                     /note="Competence induced; comG-like protein A; Also known
                     as cilD"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CglA"
                     /protein_id="NP_359455.1"
                     /db_xref="GI:15903905"
                     /db_xref="GeneID:933989"
     gene            complement(1835575..1835946)
                     /locus_tag="spr1865"
                     /db_xref="GeneID:933983"
     CDS             complement(1835575..1835946)
                     /locus_tag="spr1865"
                     /note="DNA binding protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359456.1"
                     /db_xref="GI:15903906"
                     /db_xref="GeneID:933983"
     gene            complement(1836091..1837149)
                     /gene="adh"
                     /locus_tag="spr1866"
                     /db_xref="GeneID:933984"
     CDS             complement(1836091..1837149)
                     /gene="adh"
                     /locus_tag="spr1866"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-containing alcohol dehydrogenase"
                     /protein_id="NP_359457.1"
                     /db_xref="GI:15903907"
                     /db_xref="GeneID:933984"
     gene            complement(1837312..1838463)
                     /gene="nagA"
                     /locus_tag="spr1867"
                     /db_xref="GeneID:933992"
     CDS             complement(1837312..1838463)
                     /gene="nagA"
                     /locus_tag="spr1867"
                     /EC_number="3.5.1.25"
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="NP_359458.1"
                     /db_xref="GI:15903908"
                     /db_xref="GeneID:933992"
     gene            complement(1838616..1840433)
                     /locus_tag="spr1868"
                     /db_xref="GeneID:933986"
     CDS             complement(1838616..1840433)
                     /locus_tag="spr1868"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359459.1"
                     /db_xref="GI:15903909"
                     /db_xref="GeneID:933986"
     gene            complement(1840531..1841673)
                     /gene="tgt"
                     /locus_tag="spr1869"
                     /db_xref="GeneID:933988"
     CDS             complement(1840531..1841673)
                     /gene="tgt"
                     /locus_tag="spr1869"
                     /EC_number="2.4.2.29"
                     /note="Exchanges the guanine residue with
                     7-aminomethyl-7-deazaguanine in tRNAs with GU(N)
                     anticodons (tRNA-Asp, -Asn, -His and -Tyr)"
                     /codon_start=1
                     /transl_table=11
                     /product="queuine tRNA-ribosyltransferase"
                     /protein_id="NP_359460.1"
                     /db_xref="GI:15903910"
                     /db_xref="GeneID:933988"
     gene            1841803..1842660
                     /locus_tag="spr1870"
                     /db_xref="GeneID:933994"
     CDS             1841803..1842660
                     /locus_tag="spr1870"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359461.1"
                     /db_xref="GI:15903911"
                     /db_xref="GeneID:933994"
     gene            complement(1842688..1843214)
                     /gene="pcp-truncation"
                     /locus_tag="spr1871"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933990"
     gene            complement(1843412..1843770)
                     /locus_tag="spr1873"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933997"
     gene            complement(1843781..1844119)
                     /gene="marR"
                     /locus_tag="spr1874"
                     /db_xref="GeneID:933993"
     CDS             complement(1843781..1844119)
                     /gene="marR"
                     /locus_tag="spr1874"
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="NP_359465.1"
                     /db_xref="GI:15903915"
                     /db_xref="GeneID:933993"
     repeat_region   complement(1844326..1844438)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1844525..1845667)
                     /locus_tag="spr1875"
                     /db_xref="GeneID:934001"
     CDS             complement(1844525..1845667)
                     /locus_tag="spr1875"
                     /note="Probable group B streptococcal surface immunogenic
                     protein"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359466.1"
                     /db_xref="GI:15903916"
                     /db_xref="GeneID:934001"
     gene            complement(1845833..1846453)
                     /locus_tag="spr1876"
                     /db_xref="GeneID:933995"
     CDS             complement(1845833..1846453)
                     /locus_tag="spr1876"
                     /note="Low similarity to phosphoglycolate phosphatase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359467.1"
                     /db_xref="GI:15903917"
                     /db_xref="GeneID:933995"
     gene            complement(1846457..1847737)
                     /gene="MATE_transporter"
                     /locus_tag="spr1877"
                     /db_xref="GeneID:933996"
     CDS             complement(1846457..1847737)
                     /gene="MATE_transporter"
                     /locus_tag="spr1877"
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family transporter"
                     /protein_id="NP_359468.1"
                     /db_xref="GI:15903918"
                     /db_xref="GeneID:933996"
     gene            complement(1847798..1849282)
                     /gene="thrC"
                     /locus_tag="spr1878"
                     /db_xref="GeneID:934003"
     CDS             complement(1847798..1849282)
                     /gene="thrC"
                     /locus_tag="spr1878"
                     /EC_number="4.2.3.1"
                     /note="catalyzes the formation of L-threonine from
                     O-phospho-L-homoserine"
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="NP_359469.1"
                     /db_xref="GI:15903919"
                     /db_xref="GeneID:934003"
     gene            complement(1849358..1850635)
                     /locus_tag="spr1879"
                     /db_xref="GeneID:933999"
     CDS             complement(1849358..1850635)
                     /locus_tag="spr1879"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359470.1"
                     /db_xref="GI:15903920"
                     /db_xref="GeneID:933999"
     gene            complement(1850742..1850825)
                     /gene="tRNA-Leu6"
                     /locus_tag="sprt43"
                     /db_xref="GeneID:934000"
     tRNA            complement(1850742..1850825)
                     /gene="tRNA-Leu6"
                     /locus_tag="sprt43"
                     /product="tRNA-Leu"
                     /db_xref="GeneID:934000"
     gene            complement(1850835..1850906)
                     /gene="tRNA-Gln2"
                     /locus_tag="sprt44"
                     /db_xref="GeneID:934002"
     tRNA            complement(1850835..1850906)
                     /gene="tRNA-Gln2"
                     /locus_tag="sprt44"
                     /product="tRNA-Gln"
                     /db_xref="GeneID:934002"
     gene            complement(1850917..1850989)
                     /gene="tRNA-His"
                     /locus_tag="sprt45"
                     /db_xref="GeneID:934007"
     tRNA            complement(1850917..1850989)
                     /gene="tRNA-His"
                     /locus_tag="sprt45"
                     /product="tRNA-His"
                     /db_xref="GeneID:934007"
     gene            complement(1851004..1851074)
                     /gene="tRNA-Trp"
                     /locus_tag="sprt46"
                     /db_xref="GeneID:934005"
     tRNA            complement(1851004..1851074)
                     /gene="tRNA-Trp"
                     /locus_tag="sprt46"
                     /product="tRNA-Trp"
                     /db_xref="GeneID:934005"
     gene            complement(1851079..1851159)
                     /gene="tRNA-Tyr2"
                     /locus_tag="sprt47"
                     /db_xref="GeneID:934006"
     tRNA            complement(1851079..1851159)
                     /gene="tRNA-Tyr2"
                     /locus_tag="sprt47"
                     /product="tRNA-Tyr"
                     /db_xref="GeneID:934006"
     gene            complement(1851172..1851244)
                     /gene="tRNA-Phe2"
                     /locus_tag="sprt48"
                     /db_xref="GeneID:934010"
     tRNA            complement(1851172..1851244)
                     /gene="tRNA-Phe2"
                     /locus_tag="sprt48"
                     /product="tRNA-Phe"
                     /db_xref="GeneID:934010"
     gene            complement(1851248..1851321)
                     /gene="tRNA-Met4"
                     /locus_tag="sprt49"
                     /db_xref="GeneID:934008"
     tRNA            complement(1851248..1851321)
                     /gene="tRNA-Met4"
                     /locus_tag="sprt49"
                     /product="tRNA-Met"
                     /db_xref="GeneID:934008"
     gene            complement(1851332..1851421)
                     /gene="tRNA-Ser4"
                     /locus_tag="sprt50"
                     /db_xref="GeneID:934009"
     tRNA            complement(1851332..1851421)
                     /gene="tRNA-Ser4"
                     /locus_tag="sprt50"
                     /product="tRNA-Ser"
                     /db_xref="GeneID:934009"
     gene            complement(1851505..1851578)
                     /gene="tRNA-Ile2"
                     /locus_tag="sprt51"
                     /db_xref="GeneID:934013"
     tRNA            complement(1851505..1851578)
                     /gene="tRNA-Ile2"
                     /locus_tag="sprt51"
                     /product="tRNA-Ile"
                     /db_xref="GeneID:934013"
     gene            complement(1851613..1851683)
                     /gene="tRNA-Gly4"
                     /locus_tag="sprt52"
                     /db_xref="GeneID:934011"
     tRNA            complement(1851613..1851683)
                     /gene="tRNA-Gly4"
                     /locus_tag="sprt52"
                     /product="tRNA-Gly"
                     /db_xref="GeneID:934011"
     gene            complement(1851689..1851761)
                     /gene="tRNA-Val3"
                     /locus_tag="sprt53"
                     /db_xref="GeneID:934012"
     tRNA            complement(1851689..1851761)
                     /gene="tRNA-Val3"
                     /locus_tag="sprt53"
                     /product="tRNA-Val"
                     /db_xref="GeneID:934012"
     gene            complement(1851766..1851880)
                     /gene="rRNA_5S-4"
                     /locus_tag="sprr10"
                     /db_xref="GeneID:934016"
     rRNA            complement(1851766..1851880)
                     /gene="rRNA_5S-4"
                     /locus_tag="sprr10"
                     /product="5S ribosomal RNA"
                     /db_xref="GeneID:934016"
     gene            complement(1851958..1854859)
                     /gene="rRNA_23S-4"
                     /locus_tag="sprr11"
                     /db_xref="GeneID:934014"
     rRNA            complement(1851958..1854859)
                     /gene="rRNA_23S-4"
                     /locus_tag="sprr11"
                     /product="23S ribosomal RNA"
                     /db_xref="GeneID:934014"
     gene            complement(1854984..1855056)
                     /gene="tRNA-Ala4"
                     /locus_tag="sprt54"
                     /db_xref="GeneID:934015"
     tRNA            complement(1854984..1855056)
                     /gene="tRNA-Ala4"
                     /locus_tag="sprt54"
                     /product="tRNA-Ala"
                     /db_xref="GeneID:934015"
     gene            complement(1855130..1856643)
                     /gene="rRNA_16S-4"
                     /locus_tag="sprr12"
                     /db_xref="GeneID:934020"
     rRNA            complement(1855130..1856643)
                     /gene="rRNA_16S-4"
                     /locus_tag="sprr12"
                     /product="16S ribosomal RNA"
                     /db_xref="GeneID:934020"
     gene            complement(1856906..1856977)
                     /gene="tRNA-Glu4"
                     /locus_tag="sprt55"
                     /db_xref="GeneID:934017"
     tRNA            complement(1856906..1856977)
                     /gene="tRNA-Glu4"
                     /locus_tag="sprt55"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:934017"
     gene            complement(1857099..1857533)
                     /locus_tag="spr1880"
                     /db_xref="GeneID:934018"
     CDS             complement(1857099..1857533)
                     /locus_tag="spr1880"
                     /note="Low similarity to cytidine/deoxycytidylate
                     deaminases"
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase"
                     /protein_id="NP_359471.1"
                     /db_xref="GI:15903921"
                     /db_xref="GeneID:934018"
     gene            complement(1857547..1859007)
                     /gene="gltX"
                     /locus_tag="spr1881"
                     /db_xref="GeneID:934019"
     CDS             complement(1857547..1859007)
                     /gene="gltX"
                     /locus_tag="spr1881"
                     /EC_number="6.1.1.17"
                     /note="Charges one glutamine molecule and pairs it to its
                     corresponding RNA trinucleotide during protein
                     translation"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA synthetase"
                     /protein_id="NP_359472.1"
                     /db_xref="GI:15903922"
                     /db_xref="GeneID:934019"
     gene            complement(1859131..1860480)
                     /gene="pgi"
                     /locus_tag="spr1882"
                     /db_xref="GeneID:934060"
     CDS             complement(1859131..1860480)
                     /gene="pgi"
                     /locus_tag="spr1882"
                     /EC_number="5.3.1.9"
                     /note="functions in sugar metabolism in glycolysis and the
                     Embden-Meyerhof pathways (EMP) and in gluconeogenesis;
                     catalyzes reversible isomerization of glucose-6-phosphate
                     to fructose-6-phosphate; member of PGI family"
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="NP_359473.1"
                     /db_xref="GI:15903923"
                     /db_xref="GeneID:934060"
     gene            complement(1860467..1860646)
                     /locus_tag="spr1883"
                     /db_xref="GeneID:934022"
     CDS             complement(1860467..1860646)
                     /locus_tag="spr1883"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359474.1"
                     /db_xref="GI:15903924"
                     /db_xref="GeneID:934022"
     gene            complement(1860650..1861387)
                     /gene="guaA"
                     /locus_tag="spr1884"
                     /db_xref="GeneID:934043"
     CDS             complement(1860650..1861387)
                     /gene="guaA"
                     /locus_tag="spr1884"
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="NP_359475.1"
                     /db_xref="GI:15903925"
                     /db_xref="GeneID:934043"
     gene            complement(1861478..1863289)
                     /gene="ABC-NP"
                     /locus_tag="spr1885"
                     /db_xref="GeneID:934071"
     CDS             complement(1861478..1863289)
                     /gene="ABC-NP"
                     /locus_tag="spr1885"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_359476.1"
                     /db_xref="GI:15903926"
                     /db_xref="GeneID:934071"
     gene            complement(1864031..1865725)
                     /gene="ABC-NP"
                     /locus_tag="spr1887"
                     /db_xref="GeneID:934054"
     CDS             complement(1864031..1865725)
                     /gene="ABC-NP"
                     /locus_tag="spr1887"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="NP_359478.1"
                     /db_xref="GI:15903928"
                     /db_xref="GeneID:934054"
     gene            complement(1865872..1868445)
                     /gene="hexA"
                     /locus_tag="spr1888"
                     /db_xref="GeneID:934113"
     CDS             complement(1865872..1868445)
                     /gene="hexA"
                     /locus_tag="spr1888"
                     /note="This protein performs the mismatch recognition step
                     during the DNA repair process"
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="NP_359479.1"
                     /db_xref="GI:15903929"
                     /db_xref="GeneID:934113"
     gene            complement(1868457..1868903)
                     /gene="argR"
                     /locus_tag="spr1889"
                     /db_xref="GeneID:934064"
     CDS             complement(1868457..1868903)
                     /gene="argR"
                     /locus_tag="spr1889"
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor ArgR"
                     /protein_id="NP_359480.1"
                     /db_xref="GI:15903930"
                     /db_xref="GeneID:934064"
     gene            1869051..1870742
                     /gene="argS"
                     /locus_tag="spr1890"
                     /db_xref="GeneID:934066"
     CDS             1869051..1870742
                     /gene="argS"
                     /locus_tag="spr1890"
                     /EC_number="6.1.1.19"
                     /note="catalyzes a two-step reaction, first charging an
                     arginine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA
                     synthetase"
                     /codon_start=1
                     /transl_table=11
                     /product="arginyl-tRNA synthetase"
                     /protein_id="NP_359481.1"
                     /db_xref="GI:15903931"
                     /db_xref="GeneID:934066"
     gene            complement(1871057..1871446)
                     /gene="IS1381"
                     /locus_tag="spr1891"
                     /db_xref="GeneID:934140"
     CDS             complement(1871057..1871446)
                     /gene="IS1381"
                     /locus_tag="spr1891"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_359482.1"
                     /db_xref="GI:15903932"
                     /db_xref="GeneID:934140"
     gene            1871577..1872086
                     /locus_tag="spr1892"
                     /db_xref="GeneID:934133"
     CDS             1871577..1872086
                     /locus_tag="spr1892"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359483.1"
                     /db_xref="GI:15903933"
                     /db_xref="GeneID:934133"
     gene            1872170..1872877
                     /gene="phoP_pnpR"
                     /locus_tag="spr1893"
                     /db_xref="GeneID:934134"
     CDS             1872170..1872877
                     /gene="phoP_pnpR"
                     /locus_tag="spr1893"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="NP_359484.1"
                     /db_xref="GI:15903934"
                     /db_xref="GeneID:934134"
     gene            1872878..1874209
                     /gene="phoR-pnpS"
                     /locus_tag="spr1894"
                     /db_xref="GeneID:934137"
     CDS             1872878..1874209
                     /gene="phoR-pnpS"
                     /locus_tag="spr1894"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase PnpS"
                     /protein_id="NP_359485.1"
                     /db_xref="GI:15903935"
                     /db_xref="GeneID:934137"
     gene            1874313..1875251
                     /gene="pstS"
                     /locus_tag="spr1895"
                     /db_xref="GeneID:934120"
     CDS             1874313..1875251
                     /gene="pstS"
                     /locus_tag="spr1895"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate+B766-binding
                     protein"
                     /protein_id="NP_359486.1"
                     /db_xref="GI:15903936"
                     /db_xref="GeneID:934120"
     gene            1875369..1876232
                     /gene="pstC"
                     /locus_tag="spr1896"
                     /db_xref="GeneID:934126"
     CDS             1875369..1876232
                     /gene="pstC"
                     /locus_tag="spr1896"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease"
                     /protein_id="NP_359487.1"
                     /db_xref="GI:15903937"
                     /db_xref="GeneID:934126"
     gene            1876225..1877040
                     /gene="pstA"
                     /locus_tag="spr1897"
                     /db_xref="GeneID:934117"
     CDS             1876225..1877040
                     /gene="pstA"
                     /locus_tag="spr1897"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease"
                     /protein_id="NP_359488.1"
                     /db_xref="GI:15903938"
                     /db_xref="GeneID:934117"
     gene            1877042..1877794
                     /gene="pstB"
                     /locus_tag="spr1898"
                     /db_xref="GeneID:934112"
     CDS             1877042..1877794
                     /gene="pstB"
                     /locus_tag="spr1898"
                     /note="ATP-binding protein; PstABCS is an ATP dependent
                     phosphate uptake system which is responsible for inorganic
                     phosphate uptake during phosphate starvation"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter ATP-binding protein"
                     /protein_id="NP_359489.1"
                     /db_xref="GI:15903939"
                     /db_xref="GeneID:934112"
     gene            1877809..1878459
                     /gene="phoU"
                     /locus_tag="spr1899"
                     /db_xref="GeneID:934135"
     CDS             1877809..1878459
                     /gene="phoU"
                     /locus_tag="spr1899"
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate transporter PhoU"
                     /protein_id="NP_359490.1"
                     /db_xref="GI:15903940"
                     /db_xref="GeneID:934135"
     gene            complement(1879066..1879584)
                     /locus_tag="spr1901"
                     /db_xref="GeneID:934138"
     CDS             complement(1879066..1879584)
                     /locus_tag="spr1901"
                     /note="Possible transcriptional regulator"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_359492.1"
                     /db_xref="GI:15903942"
                     /db_xref="GeneID:934138"
     gene            1879718..1880734
                     /gene="gpsA"
                     /locus_tag="spr1902"
                     /db_xref="GeneID:934131"
     CDS             1879718..1880734
                     /gene="gpsA"
                     /locus_tag="spr1902"
                     /EC_number="1.1.1.94"
                     /note="catalyzes the NAD(P)H-dependent reduction of
                     glycerol 3-phosphate to glycerone phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="NP_359493.1"
                     /db_xref="GI:15903943"
                     /db_xref="GeneID:934131"
     gene            1880756..1881655
                     /gene="galU"
                     /locus_tag="spr1903"
                     /db_xref="GeneID:934139"
     CDS             1880756..1881655
                     /gene="galU"
                     /locus_tag="spr1903"
                     /EC_number="2.7.7.9"
                     /codon_start=1
                     /transl_table=11
                     /product="UTP-glucose-1-phosphate uridylyltransferase"
                     /protein_id="NP_359494.1"
                     /db_xref="GI:15903944"
                     /db_xref="GeneID:934139"
     gene            complement(1881722..1882402)
                     /locus_tag="spr1904"
                     /db_xref="GeneID:934116"
     CDS             complement(1881722..1882402)
                     /locus_tag="spr1904"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359495.1"
                     /db_xref="GI:15903945"
                     /db_xref="GeneID:934116"
     gene            complement(1882383..1882928)
                     /locus_tag="spr1905"
                     /db_xref="GeneID:934123"
     CDS             complement(1882383..1882928)
                     /locus_tag="spr1905"
                     /note="Similar to 5-formyltetrahydrofolate cyclo-ligase"
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="NP_359496.1"
                     /db_xref="GI:15903946"
                     /db_xref="GeneID:934123"
     gene            complement(1882934..1884064)
                     /gene="hipO"
                     /locus_tag="spr1906"
                     /db_xref="GeneID:934136"
     CDS             complement(1882934..1884064)
                     /gene="hipO"
                     /locus_tag="spr1906"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359497.1"
                     /db_xref="GI:15903947"
                     /db_xref="GeneID:934136"
     gene            complement(1884132..1884830)
                     /gene="dapD"
                     /locus_tag="spr1907"
                     /db_xref="GeneID:934124"
     CDS             complement(1884132..1884830)
                     /gene="dapD"
                     /locus_tag="spr1907"
                     /EC_number="2.3.1.117"
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-carboxylate
                     N-succinyltransferase"
                     /protein_id="NP_359498.1"
                     /db_xref="GI:15903948"
                     /db_xref="GeneID:934124"
     gene            complement(1885060..1886193)
                     /locus_tag="spr1908"
                     /db_xref="GeneID:934127"
     CDS             complement(1885060..1886193)
                     /locus_tag="spr1908"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359499.1"
                     /db_xref="GI:15903949"
                     /db_xref="GeneID:934127"
     gene            complement(1886036..1888501)
                     /gene="pbp1b"
                     /locus_tag="spr1909"
                     /db_xref="GeneID:934893"
     CDS             complement(1886036..1888501)
                     /gene="pbp1b"
                     /locus_tag="spr1909"
                     /EC_number="2.3.2.-"
                     /EC_number="2.4.1.129"
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 1B"
                     /protein_id="NP_359500.1"
                     /db_xref="GI:15903950"
                     /db_xref="GeneID:934893"
     gene            1888643..1889899
                     /gene="tyrS"
                     /locus_tag="spr1910"
                     /db_xref="GeneID:934128"
     CDS             1888643..1889899
                     /gene="tyrS"
                     /locus_tag="spr1910"
                     /EC_number="6.1.1.1"
                     /note="catalyzes the formation of tyrosyl-tRNA(Tyr) from
                     tyrosine and tRNA(Tyr)"
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosyl-tRNA synthetase"
                     /protein_id="NP_359501.1"
                     /db_xref="GI:15903951"
                     /db_xref="GeneID:934128"
     gene            complement(1889977..1892049)
                     /gene="ctpC"
                     /locus_tag="spr1911"
                     /db_xref="GeneID:934119"
     CDS             complement(1889977..1892049)
                     /gene="ctpC"
                     /locus_tag="spr1911"
                     /EC_number="3.6.3.10"
                     /codon_start=1
                     /transl_table=11
                     /product="metal/cation transporter P-type ATPase"
                     /protein_id="NP_359502.1"
                     /db_xref="GI:15903952"
                     /db_xref="GeneID:934119"
     gene            complement(1892042..1892353)
                     /locus_tag="spr1912"
                     /db_xref="GeneID:934129"
     CDS             complement(1892042..1892353)
                     /locus_tag="spr1912"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359503.1"
                     /db_xref="GI:15903953"
                     /db_xref="GeneID:934129"
     gene            1892472..1893320
                     /gene="rrmA"
                     /locus_tag="spr1913"
                     /db_xref="GeneID:934132"
     CDS             1892472..1893320
                     /gene="rrmA"
                     /locus_tag="spr1913"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA (guanine-N1-)-methyltransferase"
                     /protein_id="NP_359504.1"
                     /db_xref="GI:15903954"
                     /db_xref="GeneID:934132"
     repeat_region   1893318..1893492
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1893836..1894042)
                     /locus_tag="spr1914"
                     /db_xref="GeneID:934111"
     CDS             complement(1893836..1894042)
                     /locus_tag="spr1914"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359505.1"
                     /db_xref="GI:15903955"
                     /db_xref="GeneID:934111"
     gene            1894119..1894691
                     /locus_tag="spr1915"
                     /db_xref="GeneID:934130"
     CDS             1894119..1894691
                     /locus_tag="spr1915"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359506.1"
                     /db_xref="GI:15903956"
                     /db_xref="GeneID:934130"
     repeat_region   complement(1895617..1895733)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1895736..1897994)
                     /gene="malP"
                     /locus_tag="spr1916"
                     /db_xref="GeneID:932789"
     CDS             complement(1895736..1897994)
                     /gene="malP"
                     /locus_tag="spr1916"
                     /EC_number="2.4.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="NP_359507.1"
                     /db_xref="GI:15903957"
                     /db_xref="GeneID:932789"
     gene            complement(1898020..1899537)
                     /gene="malM"
                     /locus_tag="spr1917"
                     /db_xref="GeneID:934839"
     CDS             complement(1898020..1899537)
                     /gene="malM"
                     /locus_tag="spr1917"
                     /EC_number="2.4.1.25"
                     /note="amylomaltase; acts to release glucose from
                     maltodextrins"
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="NP_359508.1"
                     /db_xref="GI:15903958"
                     /db_xref="GeneID:934839"
     gene            1900087..1901358
                     /gene="malX"
                     /locus_tag="spr1918"
                     /db_xref="GeneID:932974"
     CDS             1900087..1901358
                     /gene="malX"
                     /locus_tag="spr1918"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate+B616-binding protein"
                     /protein_id="NP_359509.1"
                     /db_xref="GI:15903959"
                     /db_xref="GeneID:932974"
     gene            1901454..1902761
                     /gene="malC"
                     /locus_tag="spr1919"
                     /db_xref="GeneID:934838"
     CDS             1901454..1902761
                     /gene="malC"
                     /locus_tag="spr1919"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin ABC transporter permease"
                     /protein_id="NP_359510.1"
                     /db_xref="GI:15903960"
                     /db_xref="GeneID:934838"
     gene            1902742..1903605
                     /gene="malD"
                     /locus_tag="spr1920"
                     /db_xref="GeneID:932952"
     CDS             1902742..1903605
                     /gene="malD"
                     /locus_tag="spr1920"
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin ABC transporter permease"
                     /protein_id="NP_359511.1"
                     /db_xref="GI:15903961"
                     /db_xref="GeneID:932952"
     repeat_region   1903628..1903728
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ac"
     gene            1903858..1904658
                     /gene="malA"
                     /locus_tag="spr1921"
                     /db_xref="GeneID:932980"
     CDS             1903858..1904658
                     /gene="malA"
                     /locus_tag="spr1921"
                     /codon_start=1
                     /transl_table=11
                     /product="MalA protein"
                     /protein_id="NP_359512.1"
                     /db_xref="GI:15903962"
                     /db_xref="GeneID:932980"
     gene            1904668..1905654
                     /gene="malR"
                     /locus_tag="spr1922"
                     /db_xref="GeneID:934853"
     CDS             1904668..1905654
                     /gene="malR"
                     /locus_tag="spr1922"
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon transcriptional repressor"
                     /protein_id="NP_359513.1"
                     /db_xref="GI:15903963"
                     /db_xref="GeneID:934853"
     repeat_region   complement(1905782..1905936)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1905946..1906887)
                     /locus_tag="spr1923"
                     /db_xref="GeneID:933407"
     CDS             complement(1905946..1906887)
                     /locus_tag="spr1923"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359514.1"
                     /db_xref="GI:15903964"
                     /db_xref="GeneID:933407"
     gene            complement(1906865..1908628)
                     /gene="aspS"
                     /locus_tag="spr1924"
                     /db_xref="GeneID:934841"
     CDS             complement(1906865..1908628)
                     /gene="aspS"
                     /locus_tag="spr1924"
                     /EC_number="6.1.1.12"
                     /note="catalyzes a two-step reaction, first charging an
                     aspartate molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; contains discriminating
                     and non-discriminating subtypes"
                     /codon_start=1
                     /transl_table=11
                     /product="aspartyl-tRNA synthetase"
                     /protein_id="NP_359515.1"
                     /db_xref="GI:15903965"
                     /db_xref="GeneID:934841"
     repeat_region   1908743..1908942
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1908980..1909210)
                     /locus_tag="spr1925"
                     /db_xref="GeneID:933582"
     CDS             complement(1908980..1909210)
                     /locus_tag="spr1925"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359516.1"
                     /db_xref="GI:15903966"
                     /db_xref="GeneID:933582"
     gene            complement(1909228..1909869)
                     /locus_tag="spr1926"
                     /db_xref="GeneID:933018"
     CDS             complement(1909228..1909869)
                     /locus_tag="spr1926"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359517.1"
                     /db_xref="GI:15903967"
                     /db_xref="GeneID:933018"
     gene            complement(1909881..1910621)
                     /locus_tag="spr1927"
                     /db_xref="GeneID:933014"
     CDS             complement(1909881..1910621)
                     /locus_tag="spr1927"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359518.1"
                     /db_xref="GI:15903968"
                     /db_xref="GeneID:933014"
     gene            complement(1910618..1910818)
                     /locus_tag="spr1928"
                     /db_xref="GeneID:934121"
     CDS             complement(1910618..1910818)
                     /locus_tag="spr1928"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359519.1"
                     /db_xref="GI:15903969"
                     /db_xref="GeneID:934121"
     gene            complement(1910815..1911030)
                     /locus_tag="spr1929"
                     /db_xref="GeneID:934842"
     CDS             complement(1910815..1911030)
                     /locus_tag="spr1929"
                     /note="transcriptional repressor protein"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="NP_359520.1"
                     /db_xref="GI:15903970"
                     /db_xref="GeneID:934842"
     gene            complement(1911031..1911495)
                     /locus_tag="spr1930"
                     /db_xref="GeneID:933027"
     CDS             complement(1911031..1911495)
                     /locus_tag="spr1930"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359521.1"
                     /db_xref="GI:15903971"
                     /db_xref="GeneID:933027"
     repeat_region   1911496..1911678
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abbc"
     gene            complement(1911671..1912960)
                     /gene="hisS"
                     /locus_tag="spr1931"
                     /db_xref="GeneID:934840"
     CDS             complement(1911671..1912960)
                     /gene="hisS"
                     /locus_tag="spr1931"
                     /EC_number="6.1.1.21"
                     /note="catalyzes a two-step reaction, first charging a
                     histidine molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA
                     synthetase; forms homodimers; some organisms have a
                     paralogous gene, hisZ, that is similar to hisS and
                     produces a protein that performs the first step in
                     histidine biosynthesis along with HisG"
                     /codon_start=1
                     /transl_table=11
                     /product="histidyl-tRNA synthetase"
                     /protein_id="NP_359522.1"
                     /db_xref="GI:15903972"
                     /db_xref="GeneID:934840"
     gene            complement(1913038..1914285)
                     /locus_tag="spr1932"
                     /db_xref="GeneID:933004"
     CDS             complement(1913038..1914285)
                     /locus_tag="spr1932"
                     /note="permease"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359523.1"
                     /db_xref="GI:15903973"
                     /db_xref="GeneID:933004"
     gene            complement(1914475..1915326)
                     /gene="rgg"
                     /locus_tag="spr1933"
                     /db_xref="GeneID:932938"
     CDS             complement(1914475..1915326)
                     /gene="rgg"
                     /locus_tag="spr1933"
                     /codon_start=1
                     /transl_table=11
                     /product="positive transcriptional regulator of
                     glucosyltransferase and Spp phenotype"
                     /protein_id="NP_359524.1"
                     /db_xref="GI:15903974"
                     /db_xref="GeneID:932938"
     gene            1915450..1915791
                     /locus_tag="spr1934"
                     /db_xref="GeneID:933034"
     CDS             1915450..1915791
                     /locus_tag="spr1934"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359525.1"
                     /db_xref="GI:15903975"
                     /db_xref="GeneID:933034"
     repeat_region   complement(1915843..1915986)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1916000..1917703)
                     /gene="ilvD"
                     /locus_tag="spr1935"
                     /db_xref="GeneID:934050"
     CDS             complement(1916000..1917703)
                     /gene="ilvD"
                     /locus_tag="spr1935"
                     /EC_number="4.2.1.9"
                     /note="catalyzes the dehydration of
                     2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate
                     in valine and isoleucine biosynthesis"
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="NP_359526.1"
                     /db_xref="GI:15903976"
                     /db_xref="GeneID:934050"
     gene            complement(1917936..1918868)
                     /gene="tktC"
                     /locus_tag="spr1936"
                     /db_xref="GeneID:934843"
     CDS             complement(1917936..1918868)
                     /gene="tktC"
                     /locus_tag="spr1936"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase C-terminal subunit"
                     /protein_id="NP_359527.1"
                     /db_xref="GI:15903977"
                     /db_xref="GeneID:934843"
     gene            complement(1918865..1919722)
                     /gene="tktN"
                     /locus_tag="spr1937"
                     /db_xref="GeneID:933053"
     CDS             complement(1918865..1919722)
                     /gene="tktN"
                     /locus_tag="spr1937"
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase N-terminal section"
                     /protein_id="NP_359528.1"
                     /db_xref="GI:15903978"
                     /db_xref="GeneID:933053"
     gene            complement(1919726..1921072)
                     /gene="ulaA"
                     /locus_tag="spr1938"
                     /gene_synonym="sgaT"
                     /db_xref="GeneID:933025"
     CDS             complement(1919726..1921072)
                     /gene="ulaA"
                     /locus_tag="spr1938"
                     /gene_synonym="sgaT"
                     /note="membrane component; functions with enzymes IIB
                     (sgaB; ulaB) and IIA (sgaA; ulaC) enzyme I and HPr for
                     anaerobic utilization and uptake of L-ascorbate; sgaTBA
                     are regulated by yifQ as well as Crp and Fnr"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system ascorbate-specific transporter
                     subunit IIC"
                     /protein_id="NP_359529.1"
                     /db_xref="GI:15903979"
                     /db_xref="GeneID:933025"
     gene            complement(1921085..1921369)
                     /locus_tag="spr1939"
                     /db_xref="GeneID:934844"
     CDS             complement(1921085..1921369)
                     /locus_tag="spr1939"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_359530.1"
                     /db_xref="GI:15903980"
                     /db_xref="GeneID:934844"
     gene            complement(1921373..1923403)
                     /locus_tag="spr1940"
                     /db_xref="GeneID:933065"
     CDS             complement(1921373..1923403)
                     /locus_tag="spr1940"
                     /note="Probable transcriptional antiterminator, bglG
                     family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359531.1"
                     /db_xref="GI:15903981"
                     /db_xref="GeneID:933065"
     gene            1923594..1924601
                     /locus_tag="spr1941"
                     /db_xref="GeneID:933064"
     CDS             1923594..1924601
                     /locus_tag="spr1941"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359532.1"
                     /db_xref="GI:15903982"
                     /db_xref="GeneID:933064"
     gene            1924604..1924804
                     /locus_tag="spr1942"
                     /db_xref="GeneID:933036"
     CDS             1924604..1924804
                     /locus_tag="spr1942"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359533.1"
                     /db_xref="GI:15903983"
                     /db_xref="GeneID:933036"
     gene            1924956..1925138
                     /gene="rpmF"
                     /locus_tag="spr1943"
                     /db_xref="GeneID:933000"
     CDS             1924956..1925138
                     /gene="rpmF"
                     /locus_tag="spr1943"
                     /note="some L32 proteins have zinc finger motifs
                     consisting of CXXC while others do not"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="NP_359534.1"
                     /db_xref="GI:15903984"
                     /db_xref="GeneID:933000"
     gene            1925154..1925303
                     /gene="rpmG"
                     /locus_tag="spr1944"
                     /db_xref="GeneID:934845"
     CDS             1925154..1925303
                     /gene="rpmG"
                     /locus_tag="spr1944"
                     /note="in Escherichia coli BM108, a mutation that results
                     in lack of L33 synthesis had no effect on ribosome
                     synthesis or function; there are paralogous genes in
                     several bacterial genomes, and a CXXC motif for zinc
                     binding and an upstream regulation region of the paralog
                     lacking this motif that are regulated by zinc similar to
                     other ribosomal proteins like L31; the proteins in this
                     group lack the CXXC motif"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="NP_359535.1"
                     /db_xref="GI:15903985"
                     /db_xref="GeneID:934845"
     gene            complement(1925783..1927855)
                     /gene="pcpA"
                     /locus_tag="spr1945"
                     /db_xref="GeneID:933069"
     CDS             complement(1925783..1927855)
                     /gene="pcpA"
                     /locus_tag="spr1945"
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding protein PcpA"
                     /protein_id="NP_359536.1"
                     /db_xref="GI:15903986"
                     /db_xref="GeneID:933069"
     gene            1928212..1928781
                     /locus_tag="spr1946"
                     /db_xref="GeneID:933077"
     CDS             1928212..1928781
                     /locus_tag="spr1946"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359537.1"
                     /db_xref="GI:15903987"
                     /db_xref="GeneID:933077"
     gene            1928807..1929196
                     /gene="IS1381"
                     /locus_tag="spr1947"
                     /db_xref="GeneID:934847"
     CDS             1928807..1929196
                     /gene="IS1381"
                     /locus_tag="spr1947"
                     /codon_start=1
                     /transl_table=11
                     /product="tranposase"
                     /protein_id="NP_359538.1"
                     /db_xref="GI:15903988"
                     /db_xref="GeneID:934847"
     gene            complement(1929248..1929720)
                     /locus_tag="spr1948"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933095"
     repeat_region   complement(1929780..1929897)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cba"
     gene            complement(1929900..1931780)
                     /locus_tag="spr1949"
                     /db_xref="GeneID:934846"
     CDS             complement(1929900..1931780)
                     /locus_tag="spr1949"
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase-like protein"
                     /protein_id="NP_359540.1"
                     /db_xref="GI:15903990"
                     /db_xref="GeneID:934846"
     gene            complement(1931774..1932655)
                     /locus_tag="spr1950"
                     /db_xref="GeneID:933076"
     CDS             complement(1931774..1932655)
                     /locus_tag="spr1950"
                     /note="sugar operon regulatory protein"
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="NP_359541.1"
                     /db_xref="GI:15903991"
                     /db_xref="GeneID:933076"
     gene            complement(1932727..1935387)
                     /locus_tag="spr1951"
                     /db_xref="GeneID:933083"
     CDS             complement(1932727..1935387)
                     /locus_tag="spr1951"
                     /note="Probable sugar hydrolase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359542.1"
                     /db_xref="GI:15903992"
                     /db_xref="GeneID:933083"
     gene            complement(1935463..1936767)
                     /locus_tag="spr1952"
                     /db_xref="GeneID:933101"
     CDS             complement(1935463..1936767)
                     /locus_tag="spr1952"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359543.1"
                     /db_xref="GI:15903993"
                     /db_xref="GeneID:933101"
     gene            1936914..1938998
                     /locus_tag="spr1953"
                     /db_xref="GeneID:933282"
     CDS             1936914..1938998
                     /locus_tag="spr1953"
                     /note="Similar to a sugar hydrolase in Lactococcus lactis
                     subsp. lactis"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359544.1"
                     /db_xref="GI:15903994"
                     /db_xref="GeneID:933282"
     gene            complement(1939038..1940789)
                     /locus_tag="spr1954"
                     /db_xref="GeneID:933075"
     CDS             complement(1939038..1940789)
                     /locus_tag="spr1954"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359545.1"
                     /db_xref="GI:15903995"
                     /db_xref="GeneID:933075"
     gene            1941478..1942711
                     /gene="arcA-truncation"
                     /locus_tag="spr1955"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933088"
     gene            1942769..1943785
                     /gene="arcB"
                     /locus_tag="spr1957"
                     /db_xref="GeneID:932991"
     CDS             1942769..1943785
                     /gene="arcB"
                     /locus_tag="spr1957"
                     /EC_number="2.1.3.3"
                     /note="catalyzes the formation of ornithine and
                     carbamylphosphate from citrulline in the arginine
                     catabolic pathway"
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="NP_359548.1"
                     /db_xref="GI:15903998"
                     /db_xref="GeneID:932991"
     gene            1943950..1944897
                     /gene="arcC"
                     /locus_tag="spr1958"
                     /db_xref="GeneID:934851"
     CDS             1943950..1944897
                     /gene="arcC"
                     /locus_tag="spr1958"
                     /EC_number="2.7.2.2"
                     /note="catalyzes the reversible synthesis of carbamate and
                     ATP from carbamoyl phosphate and ADP"
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="NP_359549.1"
                     /db_xref="GI:15903999"
                     /db_xref="GeneID:934851"
     gene            1945106..1946617
                     /locus_tag="spr1959"
                     /db_xref="GeneID:933363"
     CDS             1945106..1946617
                     /locus_tag="spr1959"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359550.1"
                     /db_xref="GI:15904000"
                     /db_xref="GeneID:933363"
     gene            1946639..1947970
                     /locus_tag="spr1960"
                     /db_xref="GeneID:933289"
     CDS             1946639..1947970
                     /locus_tag="spr1960"
                     /note="Probable Xaa-His dipeptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359551.1"
                     /db_xref="GI:15904001"
                     /db_xref="GeneID:933289"
     repeat_region   1948268..1948374
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(1948375..1948665)
                     /locus_tag="spr1961"
                     /db_xref="GeneID:933261"
     CDS             complement(1948375..1948665)
                     /locus_tag="spr1961"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359552.1"
                     /db_xref="GI:15904002"
                     /db_xref="GeneID:933261"
     repeat_region   complement(1949095..1949293)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_cbba"
     gene            complement(1949304..1950203)
                     /locus_tag="spr1962"
                     /db_xref="GeneID:933066"
     CDS             complement(1949304..1950203)
                     /locus_tag="spr1962"
                     /note="Probable member of SPFH domain/Band 7 family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359553.1"
                     /db_xref="GI:15904003"
                     /db_xref="GeneID:933066"
     gene            complement(1950333..1951484)
                     /gene="adh2"
                     /locus_tag="spr1963"
                     /db_xref="GeneID:933050"
     CDS             complement(1950333..1951484)
                     /gene="adh2"
                     /locus_tag="spr1963"
                     /EC_number="1.1.1.1"
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="NP_359554.1"
                     /db_xref="GI:15904004"
                     /db_xref="GeneID:933050"
     gene            complement(1951630..1953396)
                     /gene="fucI"
                     /locus_tag="spr1964"
                     /db_xref="GeneID:933146"
     CDS             complement(1951630..1953396)
                     /gene="fucI"
                     /locus_tag="spr1964"
                     /EC_number="5.3.1.25"
                     /note="catalyzes the conversion of the aldose L-fucose
                     into the corresponding ketose L-fuculose"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="NP_359555.1"
                     /db_xref="GI:15904005"
                     /db_xref="GeneID:933146"
     gene            complement(1953453..1956569)
                     /locus_tag="spr1965"
                     /db_xref="GeneID:933903"
     CDS             complement(1953453..1956569)
                     /locus_tag="spr1965"
                     /codon_start=1
                     /transl_table=11
                     /product="fucolectin-related protein"
                     /protein_id="NP_359556.1"
                     /db_xref="GI:15904006"
                     /db_xref="GeneID:933903"
     gene            complement(1956579..1958873)
                     /locus_tag="spr1966"
                     /db_xref="GeneID:934848"
     CDS             complement(1956579..1958873)
                     /locus_tag="spr1966"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359557.1"
                     /db_xref="GI:15904007"
                     /db_xref="GeneID:934848"
     gene            complement(1958932..1959732)
                     /gene="PTS-EII"
                     /locus_tag="spr1967"
                     /db_xref="GeneID:933119"
     CDS             complement(1958932..1959732)
                     /gene="PTS-EII"
                     /locus_tag="spr1967"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IID"
                     /protein_id="NP_359558.1"
                     /db_xref="GI:15904008"
                     /db_xref="GeneID:933119"
     gene            complement(1959729..1960502)
                     /gene="PTS-EII"
                     /locus_tag="spr1968"
                     /db_xref="GeneID:933265"
     CDS             complement(1959729..1960502)
                     /gene="PTS-EII"
                     /locus_tag="spr1968"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIC"
                     /protein_id="NP_359559.1"
                     /db_xref="GI:15904009"
                     /db_xref="GeneID:933265"
     gene            complement(1960527..1960997)
                     /gene="PTS-EII"
                     /locus_tag="spr1969"
                     /db_xref="GeneID:934849"
     CDS             complement(1960527..1960997)
                     /gene="PTS-EII"
                     /locus_tag="spr1969"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIB"
                     /protein_id="NP_359560.1"
                     /db_xref="GI:15904010"
                     /db_xref="GeneID:934849"
     gene            complement(1960988..1961434)
                     /gene="PTS-EII"
                     /locus_tag="spr1970"
                     /db_xref="GeneID:933110"
     CDS             complement(1960988..1961434)
                     /gene="PTS-EII"
                     /locus_tag="spr1970"
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system transporter subunit IIA"
                     /protein_id="NP_359561.1"
                     /db_xref="GI:15904011"
                     /db_xref="GeneID:933110"
     gene            complement(1961412..1961852)
                     /gene="fucU"
                     /locus_tag="spr1971"
                     /db_xref="GeneID:933886"
     CDS             complement(1961412..1961852)
                     /gene="fucU"
                     /locus_tag="spr1971"
                     /codon_start=1
                     /transl_table=11
                     /product="fucose pathway protein"
                     /protein_id="NP_359562.1"
                     /db_xref="GI:15904012"
                     /db_xref="GeneID:933886"
     gene            complement(1961864..1962517)
                     /gene="fucA"
                     /locus_tag="spr1972"
                     /db_xref="GeneID:932993"
     CDS             complement(1961864..1962517)
                     /gene="fucA"
                     /locus_tag="spr1972"
                     /EC_number="4.1.2.17"
                     /note="catalyzes the formation of glycerone phosphate and
                     (S)-lactaldehyde from L-fuculose 1-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose phosphate aldolase"
                     /protein_id="NP_359563.1"
                     /db_xref="GI:15904013"
                     /db_xref="GeneID:932993"
     gene            complement(1962617..1964065)
                     /gene="fcsK"
                     /locus_tag="spr1973"
                     /db_xref="GeneID:932925"
     CDS             complement(1962617..1964065)
                     /gene="fcsK"
                     /locus_tag="spr1973"
                     /EC_number="2.7.1.5"
                     /codon_start=1
                     /transl_table=11
                     /product="fucose kinase"
                     /protein_id="NP_359564.1"
                     /db_xref="GI:15904014"
                     /db_xref="GeneID:932925"
     gene            1964196..1964969
                     /gene="fcsR"
                     /locus_tag="spr1974"
                     /db_xref="GeneID:934850"
     CDS             1964196..1964969
                     /gene="fcsR"
                     /locus_tag="spr1974"
                     /codon_start=1
                     /transl_table=11
                     /product="fucose operon repressor"
                     /protein_id="NP_359565.1"
                     /db_xref="GI:15904015"
                     /db_xref="GeneID:934850"
     repeat_region   complement(1964958..1965088)
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_ca"
     gene            complement(1966098..1967603)
                     /gene="adcA"
                     /locus_tag="spr1975"
                     /db_xref="GeneID:933277"
     CDS             complement(1966098..1967603)
                     /gene="adcA"
                     /locus_tag="spr1975"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="NP_359566.1"
                     /db_xref="GI:15904016"
                     /db_xref="GeneID:933277"
     gene            complement(1967613..1968449)
                     /gene="adcB"
                     /locus_tag="spr1976"
                     /db_xref="GeneID:934852"
     CDS             complement(1967613..1968449)
                     /gene="adcB"
                     /locus_tag="spr1976"
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease"
                     /protein_id="NP_359567.1"
                     /db_xref="GI:15904017"
                     /db_xref="GeneID:934852"
     gene            complement(1968412..1969116)
                     /gene="adcC"
                     /locus_tag="spr1977"
                     /db_xref="GeneID:933425"
     CDS             complement(1968412..1969116)
                     /gene="adcC"
                     /locus_tag="spr1977"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATPase"
                     /protein_id="NP_359568.1"
                     /db_xref="GI:15904018"
                     /db_xref="GeneID:933425"
     gene            complement(1969116..1969616)
                     /gene="adcR"
                     /locus_tag="spr1978"
                     /db_xref="GeneID:933868"
     CDS             complement(1969116..1969616)
                     /gene="adcR"
                     /locus_tag="spr1978"
                     /codon_start=1
                     /transl_table=11
                     /product="adc operon repressor AdcR"
                     /protein_id="NP_359569.1"
                     /db_xref="GI:15904019"
                     /db_xref="GeneID:933868"
     gene            complement(1969711..1970994)
                     /gene="dltD"
                     /locus_tag="spr1979"
                     /db_xref="GeneID:933943"
     CDS             complement(1969711..1970994)
                     /gene="dltD"
                     /locus_tag="spr1979"
                     /codon_start=1
                     /transl_table=11
                     /product="poly D-alanine transfer protein"
                     /protein_id="NP_359570.1"
                     /db_xref="GI:15904020"
                     /db_xref="GeneID:933943"
     gene            complement(1970972..1971211)
                     /gene="dltC"
                     /locus_tag="spr1980"
                     /db_xref="GeneID:934854"
     CDS             complement(1970972..1971211)
                     /gene="dltC"
                     /locus_tag="spr1980"
                     /EC_number="6.1.1.13"
                     /note="D-alanyl carrier protein subunit; involved in the
                     incorporation of D-alanine into membrane-associated
                     D-alanyl-lipoteichoic acid; D-alanyl carrier protein is
                     the acceptor of activated D-alanine which it donates to a
                     membrane acceptor(D-alanyl transferase) for incorporation
                     into membrane lipoteichoic acid"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     2"
                     /protein_id="NP_359571.1"
                     /db_xref="GI:15904021"
                     /db_xref="GeneID:934854"
     gene            complement(1971225..1972469)
                     /gene="dltB"
                     /locus_tag="spr1981"
                     /db_xref="GeneID:933707"
     CDS             complement(1971225..1972469)
                     /gene="dltB"
                     /locus_tag="spr1981"
                     /note="D-alanine transfer from Dcp to
                     undecaprenol-phosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="activated D-alanine transport protein"
                     /protein_id="NP_359572.1"
                     /db_xref="GI:15904022"
                     /db_xref="GeneID:933707"
     gene            complement(1972466..1973932)
                     /gene="dltA"
                     /locus_tag="spr1982"
                     /db_xref="GeneID:934087"
     CDS             complement(1972466..1973932)
                     /gene="dltA"
                     /locus_tag="spr1982"
                     /EC_number="6.1.1.13"
                     /note="transfers D-alanine to the D-alanyl carrier protein
                     during the incorporation of D-alanine into lipoteichoic
                     acid"
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     1"
                     /protein_id="NP_359573.1"
                     /db_xref="GI:15904023"
                     /db_xref="GeneID:934087"
     gene            complement(1974482..1975660)
                     /locus_tag="spr1983"
                     /db_xref="GeneID:933708"
     CDS             complement(1974482..1975660)
                     /locus_tag="spr1983"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359574.1"
                     /db_xref="GI:15904024"
                     /db_xref="GeneID:933708"
     gene            complement(1976116..1977393)
                     /gene="transposase_H"
                     /locus_tag="spr1984"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934086"
     gene            1978504..1979091
                     /locus_tag="spr1986"
                     /db_xref="GeneID:933486"
     CDS             1978504..1979091
                     /locus_tag="spr1986"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359577.1"
                     /db_xref="GI:15904027"
                     /db_xref="GeneID:933486"
     gene            complement(1979178..1979381)
                     /locus_tag="spr1987"
                     /db_xref="GeneID:934871"
     CDS             complement(1979178..1979381)
                     /locus_tag="spr1987"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359578.1"
                     /db_xref="GI:15904028"
                     /db_xref="GeneID:934871"
     gene            complement(1979572..1980276)
                     /gene="glpF"
                     /locus_tag="spr1988"
                     /db_xref="GeneID:933711"
     CDS             complement(1979572..1980276)
                     /gene="glpF"
                     /locus_tag="spr1988"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein"
                     /protein_id="NP_359579.1"
                     /db_xref="GI:15904029"
                     /db_xref="GeneID:933711"
     gene            complement(1980346..1982174)
                     /gene="glpD-truncation"
                     /locus_tag="spr1989"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934090"
     gene            complement(1982216..1983724)
                     /gene="glpK"
                     /locus_tag="spr1991"
                     /db_xref="GeneID:933712"
     CDS             complement(1982216..1983724)
                     /gene="glpK"
                     /locus_tag="spr1991"
                     /EC_number="2.7.1.30"
                     /note="Converts glycerol and ADP to glycerol-3-phosphate
                     and ADP"
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase"
                     /protein_id="NP_359582.1"
                     /db_xref="GI:15904032"
                     /db_xref="GeneID:933712"
     gene            complement(1983883..1985310)
                     /locus_tag="spr1992"
                     /db_xref="GeneID:934088"
     CDS             complement(1983883..1985310)
                     /locus_tag="spr1992"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359583.1"
                     /db_xref="GI:15904033"
                     /db_xref="GeneID:934088"
     gene            1985475..1986347
                     /gene="hslO"
                     /locus_tag="spr1993"
                     /db_xref="GeneID:934856"
     CDS             1985475..1986347
                     /gene="hslO"
                     /locus_tag="spr1993"
                     /note="becomes active under oxidative stress; four
                     conserved cysteines bind a zinc atom when they are in the
                     reduced state and the enzyme is inactive; oxidative stress
                     results in oxidized cysteines, release of zinc, and
                     binding of Hsp33 to aggregation-prone proteins; forms
                     dimers and higher order oligomers"
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33-like chaperonin"
                     /protein_id="NP_359584.1"
                     /db_xref="GI:15904034"
                     /db_xref="GeneID:934856"
     gene            1986304..1987314
                     /locus_tag="spr1994"
                     /db_xref="GeneID:933713"
     CDS             1986304..1987314
                     /locus_tag="spr1994"
                     /note="Falls into the same paralogous family as
                     dihydroorotate dehydrogenase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359585.1"
                     /db_xref="GI:15904035"
                     /db_xref="GeneID:933713"
     gene            complement(1987544..1989649)
                     /gene="pspC"
                     /locus_tag="spr1995"
                     /db_xref="GeneID:933487"
     CDS             complement(1987544..1989649)
                     /gene="pspC"
                     /locus_tag="spr1995"
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding protein A"
                     /protein_id="NP_359586.1"
                     /db_xref="GI:15904036"
                     /db_xref="GeneID:933487"
     gene            complement(1989728..1990255)
                     /locus_tag="spr1996"
                     /db_xref="GeneID:934857"
     CDS             complement(1989728..1990255)
                     /locus_tag="spr1996"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359587.1"
                     /db_xref="GI:15904037"
                     /db_xref="GeneID:934857"
     gene            complement(1990338..1991669)
                     /gene="hk06"
                     /locus_tag="spr1997"
                     /db_xref="GeneID:933715"
     CDS             complement(1990338..1991669)
                     /gene="hk06"
                     /locus_tag="spr1997"
                     /EC_number="2.7.3.-"
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="NP_359588.1"
                     /db_xref="GI:15904038"
                     /db_xref="GeneID:933715"
     gene            complement(1991666..1992319)
                     /gene="rr06"
                     /locus_tag="spr1998"
                     /db_xref="GeneID:934089"
     CDS             complement(1991666..1992319)
                     /gene="rr06"
                     /locus_tag="spr1998"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="NP_359589.1"
                     /db_xref="GI:15904039"
                     /db_xref="GeneID:934089"
     repeat_region   1992478..1992586
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     repeat_region   1992799..1992909
                     /rpt_family="BOX element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="box_abc"
     gene            complement(1993212..1995393)
                     /gene="clpC-truncation"
                     /locus_tag="spr1999"
                     /pseudogene="unknown"
                     /db_xref="GeneID:933488"
     gene            complement(1995395..1995916)
                     /gene="ctsR"
                     /locus_tag="spr2001"
                     /db_xref="GeneID:933717"
     CDS             complement(1995395..1995916)
                     /gene="ctsR"
                     /locus_tag="spr2001"
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CtsR"
                     /protein_id="NP_359592.1"
                     /db_xref="GI:15904042"
                     /db_xref="GeneID:933717"
     gene            complement(1995972..1996700)
                     /gene="ABC-NBD"
                     /locus_tag="spr2002"
                     /db_xref="GeneID:934094"
     CDS             complement(1995972..1996700)
                     /gene="ABC-NBD"
                     /locus_tag="spr2002"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359593.1"
                     /db_xref="GI:15904043"
                     /db_xref="GeneID:934094"
     gene            complement(1996700..1997707)
                     /locus_tag="spr2003"
                     /db_xref="GeneID:934861"
     CDS             complement(1996700..1997707)
                     /locus_tag="spr2003"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="NP_359594.1"
                     /db_xref="GI:15904044"
                     /db_xref="GeneID:934861"
     gene            complement(1997745..1998506)
                     /gene="ABC-MSP"
                     /locus_tag="spr2004"
                     /db_xref="GeneID:933718"
     CDS             complement(1997745..1998506)
                     /gene="ABC-MSP"
                     /locus_tag="spr2004"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359595.1"
                     /db_xref="GI:15904045"
                     /db_xref="GeneID:933718"
     gene            complement(1998466..1998756)
                     /locus_tag="spr2005"
                     /db_xref="GeneID:934092"
     CDS             complement(1998466..1998756)
                     /locus_tag="spr2005"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359596.1"
                     /db_xref="GI:15904046"
                     /db_xref="GeneID:934092"
     gene            complement(1999012..2000358)
                     /gene="cbpD"
                     /locus_tag="spr2006"
                     /db_xref="GeneID:934859"
     CDS             complement(1999012..2000358)
                     /gene="cbpD"
                     /locus_tag="spr2006"
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding protein D"
                     /protein_id="NP_359597.1"
                     /db_xref="GI:15904047"
                     /db_xref="GeneID:934859"
     gene            complement(2000447..2000713)
                     /locus_tag="spr2007"
                     /db_xref="GeneID:933719"
     CDS             complement(2000447..2000713)
                     /locus_tag="spr2007"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359598.1"
                     /db_xref="GI:15904048"
                     /db_xref="GeneID:933719"
     gene            complement(2000715..2002067)
                     /gene="dnaC"
                     /locus_tag="spr2008"
                     /db_xref="GeneID:933489"
     CDS             complement(2000715..2002067)
                     /gene="dnaC"
                     /locus_tag="spr2008"
                     /note="unwinds double stranded DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="NP_359599.1"
                     /db_xref="GI:15904049"
                     /db_xref="GeneID:933489"
     gene            complement(2002111..2002563)
                     /gene="rplI"
                     /locus_tag="spr2009"
                     /db_xref="GeneID:934865"
     CDS             complement(2002111..2002563)
                     /gene="rplI"
                     /locus_tag="spr2009"
                     /note="in Escherichia coli this protein is wrapped around
                     the base of the L1 stalk"
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="NP_359600.1"
                     /db_xref="GI:15904050"
                     /db_xref="GeneID:934865"
     gene            complement(2002560..2004533)
                     /locus_tag="spr2010"
                     /db_xref="GeneID:933720"
     CDS             complement(2002560..2004533)
                     /locus_tag="spr2010"
                     /note="Probable member of DHH superfamily"
                     /codon_start=1
                     /transl_table=11
                     /product="DHH subfamily 1 protein"
                     /protein_id="NP_359601.1"
                     /db_xref="GI:15904051"
                     /db_xref="GeneID:933720"
     gene            complement(2004669..2005217)
                     /locus_tag="spr2011"
                     /db_xref="GeneID:934097"
     CDS             complement(2004669..2005217)
                     /locus_tag="spr2011"
                     /note="Probable member of ribosomal protein S30AE family"
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal subunit interface protein"
                     /protein_id="NP_359602.1"
                     /db_xref="GI:15904052"
                     /db_xref="GeneID:934097"
     gene            complement(2005297..2005959)
                     /gene="comFC"
                     /locus_tag="spr2012"
                     /db_xref="GeneID:934860"
     CDS             complement(2005297..2005959)
                     /gene="comFC"
                     /locus_tag="spr2012"
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComF"
                     /protein_id="NP_359603.1"
                     /db_xref="GI:15904053"
                     /db_xref="GeneID:934860"
     gene            complement(2005956..2007254)
                     /gene="comFA"
                     /locus_tag="spr2013"
                     /db_xref="GeneID:933722"
     CDS             complement(2005956..2007254)
                     /gene="comFA"
                     /locus_tag="spr2013"
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="NP_359604.1"
                     /db_xref="GI:15904054"
                     /db_xref="GeneID:933722"
     gene            2007310..2007945
                     /locus_tag="spr2014"
                     /db_xref="GeneID:934091"
     CDS             2007310..2007945
                     /locus_tag="spr2014"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359605.1"
                     /db_xref="GI:15904055"
                     /db_xref="GeneID:934091"
     gene            2008230..2009150
                     /gene="cycK"
                     /locus_tag="spr2015"
                     /db_xref="GeneID:933723"
     CDS             2008230..2009150
                     /gene="cycK"
                     /locus_tag="spr2015"
                     /EC_number="2.5.1.47"
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase"
                     /protein_id="NP_359606.1"
                     /db_xref="GI:15904056"
                     /db_xref="GeneID:933723"
     gene            complement(2009347..2009616)
                     /gene="transposase_G"
                     /locus_tag="spr2016"
                     /db_xref="GeneID:933490"
     CDS             complement(2009347..2009616)
                     /gene="transposase_G"
                     /locus_tag="spr2016"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359607.1"
                     /db_xref="GI:15904057"
                     /db_xref="GeneID:933490"
     repeat_region   complement(2010058..2010164)
                     /rpt_family="RUP element"
                     /rpt_type=dispersed
                     /rpt_unit_seq="rup_a"
     gene            complement(2010734..2011774)
                     /gene="tsf"
                     /locus_tag="spr2019"
                     /db_xref="GeneID:933725"
     CDS             complement(2010734..2011774)
                     /gene="tsf"
                     /locus_tag="spr2019"
                     /note="EF-Ts; functions during elongation stage of protein
                     translation; forms a dimer; associates with EF-Tu-GDP
                     complex and promotes exchange of GDP to GTP resulting in
                     regeneration of the active form of EF-Tu"
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="NP_359610.1"
                     /db_xref="GI:15904060"
                     /db_xref="GeneID:933725"
     gene            complement(2011840..2012619)
                     /gene="rpsB"
                     /locus_tag="spr2020"
                     /db_xref="GeneID:934093"
     CDS             complement(2011840..2012619)
                     /gene="rpsB"
                     /locus_tag="spr2020"
                     /note="one of the last subunits in the assembly of the 30S
                     subunit; absence of S2 does not inhibit assembly but
                     results in an inactive subunit"
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="NP_359611.1"
                     /db_xref="GI:15904061"
                     /db_xref="GeneID:934093"
     gene            complement(2012843..2014021)
                     /gene="gsp-781"
                     /locus_tag="spr2021"
                     /db_xref="GeneID:933726"
     CDS             complement(2012843..2014021)
                     /gene="gsp-781"
                     /locus_tag="spr2021"
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein GSP-781"
                     /protein_id="NP_359612.1"
                     /db_xref="GI:15904062"
                     /db_xref="GeneID:933726"
     gene            complement(2014115..2014609)
                     /gene="mreD"
                     /locus_tag="spr2022"
                     /db_xref="GeneID:933491"
     CDS             complement(2014115..2014609)
                     /gene="mreD"
                     /locus_tag="spr2022"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shpae-determining protein MreD"
                     /protein_id="NP_359613.1"
                     /db_xref="GI:15904063"
                     /db_xref="GeneID:933491"
     gene            complement(2014609..2015427)
                     /gene="mreC"
                     /locus_tag="spr2023"
                     /db_xref="GeneID:934863"
     CDS             complement(2014609..2015427)
                     /gene="mreC"
                     /locus_tag="spr2023"
                     /note="in some organisms this protein is a transmembrane
                     protein while in others it is periplasmic; involved in
                     some organisms with other components of the MreBCD complex
                     and with penicillin binding proteins in the periplasm or
                     cell wall"
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="NP_359614.1"
                     /db_xref="GI:15904064"
                     /db_xref="GeneID:934863"
     gene            complement(2015486..2016280)
                     /gene="ABC-MSP"
                     /locus_tag="spr2024"
                     /db_xref="GeneID:933727"
     CDS             complement(2015486..2016280)
                     /gene="ABC-MSP"
                     /locus_tag="spr2024"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359615.1"
                     /db_xref="GI:15904065"
                     /db_xref="GeneID:933727"
     gene            complement(2016273..2017112)
                     /gene="cbiO"
                     /locus_tag="spr2025"
                     /db_xref="GeneID:934095"
     CDS             complement(2016273..2017112)
                     /gene="cbiO"
                     /locus_tag="spr2025"
                     /note="with CbiNQ forms the ABC transporter for cobalt
                     import; Streptococcus has two adjacent copies of this
                     gene"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt transporter ATP-binding subunit"
                     /protein_id="NP_359616.1"
                     /db_xref="GI:15904066"
                     /db_xref="GeneID:934095"
     gene            complement(2017097..2017924)
                     /gene="cbiO"
                     /locus_tag="spr2026"
                     /db_xref="GeneID:934864"
     CDS             complement(2017097..2017924)
                     /gene="cbiO"
                     /locus_tag="spr2026"
                     /note="with CbiNQ forms the ABC transporter for cobalt
                     import; Streptococcus has two adjacent copies of this
                     gene"
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt transporter ATP-binding subunit"
                     /protein_id="NP_359617.1"
                     /db_xref="GI:15904067"
                     /db_xref="GeneID:934864"
     gene            complement(2017921..2018466)
                     /gene="pgsA"
                     /locus_tag="spr2027"
                     /db_xref="GeneID:933728"
     CDS             complement(2017921..2018466)
                     /gene="pgsA"
                     /locus_tag="spr2027"
                     /EC_number="2.7.8.5"
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="NP_359618.1"
                     /db_xref="GI:15904068"
                     /db_xref="GeneID:933728"
     gene            complement(2018477..2019307)
                     /locus_tag="spr2028"
                     /db_xref="GeneID:934098"
     CDS             complement(2018477..2019307)
                     /locus_tag="spr2028"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359619.1"
                     /db_xref="GI:15904069"
                     /db_xref="GeneID:934098"
     gene            complement(2019340..2020623)
                     /locus_tag="spr2029"
                     /db_xref="GeneID:934872"
     CDS             complement(2019340..2020623)
                     /locus_tag="spr2029"
                     /note="Probable protease/peptidase"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359620.1"
                     /db_xref="GI:15904070"
                     /db_xref="GeneID:934872"
     gene            complement(2020620..2021870)
                     /locus_tag="spr2030"
                     /db_xref="GeneID:933729"
     CDS             complement(2020620..2021870)
                     /locus_tag="spr2030"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359621.1"
                     /db_xref="GI:15904071"
                     /db_xref="GeneID:933729"
     gene            2022029..2022397
                     /locus_tag="spr2031"
                     /db_xref="GeneID:934101"
     CDS             2022029..2022397
                     /locus_tag="spr2031"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359622.1"
                     /db_xref="GI:15904072"
                     /db_xref="GeneID:934101"
     gene            2022400..2023497
                     /gene="recF"
                     /locus_tag="spr2032"
                     /db_xref="GeneID:934866"
     CDS             2022400..2023497
                     /gene="recF"
                     /locus_tag="spr2032"
                     /note="Required for DNA replication; binds preferentially
                     to single-stranded, linear DNA"
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein F"
                     /protein_id="NP_359623.1"
                     /db_xref="GI:15904073"
                     /db_xref="GeneID:934866"
     gene            complement(2023548..2025026)
                     /gene="imdH"
                     /locus_tag="spr2033"
                     /db_xref="GeneID:933730"
     CDS             complement(2023548..2025026)
                     /gene="imdH"
                     /locus_tag="spr2033"
                     /EC_number="1.1.1.205"
                     /note="catalyzes the synthesis of xanthosine monophosphate
                     by the NAD+ dependent oxidation of inosine monophosphate"
                     /codon_start=1
                     /transl_table=11
                     /product="inosine 5'-monophosphate dehydrogenase"
                     /protein_id="NP_359624.1"
                     /db_xref="GI:15904074"
                     /db_xref="GeneID:933730"
     gene            complement(2025178..2026203)
                     /gene="trpS"
                     /locus_tag="spr2034"
                     /db_xref="GeneID:933492"
     CDS             complement(2025178..2026203)
                     /gene="trpS"
                     /locus_tag="spr2034"
                     /EC_number="6.1.1.2"
                     /note="catalyzes a two-step reaction, first charging a
                     tryptophan molecule by linking its carboxyl group to the
                     alpha-phosphate of ATP, followed by transfer of the
                     aminoacyl-adenylate to its tRNA"
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanyl-tRNA synthetase II"
                     /protein_id="NP_359625.1"
                     /db_xref="GI:15904075"
                     /db_xref="GeneID:933492"
     gene            2026409..2028031
                     /gene="ABC-NBD"
                     /locus_tag="spr2035"
                     /db_xref="GeneID:934867"
     CDS             2026409..2028031
                     /gene="ABC-NBD"
                     /locus_tag="spr2035"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="NP_359626.1"
                     /db_xref="GI:15904076"
                     /db_xref="GeneID:934867"
     gene            2028093..2030645
                     /locus_tag="spr2036"
                     /db_xref="GeneID:933731"
     CDS             2028093..2030645
                     /locus_tag="spr2036"
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="NP_359627.1"
                     /db_xref="GI:15904077"
                     /db_xref="GeneID:933731"
     gene            complement(2030746..2032278)
                     /locus_tag="spr2037"
                     /pseudogene="unknown"
                     /db_xref="GeneID:934099"
     gene            2032457..2032999
                     /locus_tag="spr2040"
                     /db_xref="GeneID:934096"
     CDS             2032457..2032999
                     /locus_tag="spr2040"
                     /note="Probable transcriptional regulator of TetR family"
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="NP_359631.1"
                     /db_xref="GI:15904081"
                     /db_xref="GeneID:934096"
     gene            complement(2033040..2033113)
                     /gene="tRNA-Asn2"
                     /locus_tag="sprt56"
                     /db_xref="GeneID:934869"
     tRNA            complement(2033040..2033113)
                     /gene="tRNA-Asn2"
                     /locus_tag="sprt56"
                     /product="tRNA-Asn"
                     /db_xref="GeneID:934869"
     gene            complement(2033119..2033190)
                     /gene="tRNA-Glu5"
                     /locus_tag="sprt57"
                     /db_xref="GeneID:933494"
     tRNA            complement(2033119..2033190)
                     /gene="tRNA-Glu5"
                     /locus_tag="sprt57"
                     /product="tRNA-Glu"
                     /db_xref="GeneID:933494"
     gene            complement(2033242..2033994)
                     /gene="comE"
                     /locus_tag="spr2041"
                     /db_xref="GeneID:933733"
     CDS             complement(2033242..2033994)
                     /gene="comE"
                     /locus_tag="spr2041"
                     /note="Required for induction of competence"
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="NP_359632.1"
                     /db_xref="GI:15904082"
                     /db_xref="GeneID:933733"
     gene            complement(2033991..2035316)
                     /gene="comD"
                     /locus_tag="spr2042"
                     /db_xref="GeneID:934103"
     CDS             complement(2033991..2035316)
                     /gene="comD"
                     /locus_tag="spr2042"
                     /EC_number="2.7.3.-"
                     /note="Required for induction of competence"
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase ComD"
                     /protein_id="NP_359633.1"
                     /db_xref="GI:15904083"
                     /db_xref="GeneID:934103"
     gene            complement(2035337..2035462)
                     /gene="comC"
                     /locus_tag="spr2043"
                     /db_xref="GeneID:934870"
     CDS             complement(2035337..2035462)
                     /gene="comC"
                     /locus_tag="spr2043"
                     /codon_start=1
                     /transl_table=11
                     /product="competence stimulating peptide"
                     /protein_id="NP_359634.1"
                     /db_xref="GI:15904084"
                     /db_xref="GeneID:934870"
     gene            complement(2035627..2035700)
                     /gene="tRNA-Arg5"
                     /locus_tag="sprt58"
                     /db_xref="GeneID:933734"
     tRNA            complement(2035627..2035700)
                     /gene="tRNA-Arg5"
                     /locus_tag="sprt58"
                     /product="tRNA-Arg"
                     /db_xref="GeneID:933734"
     gene            complement(2035744..2036223)
                     /locus_tag="spr2044"
                     /db_xref="GeneID:933736"
     CDS             complement(2035744..2036223)
                     /locus_tag="spr2044"
                     /note="SPOUT methyltransferase; crystal structure shows
                     homodimer; in Escherichia coli this protein methylates
                     pseudouridine at position 1915 of the 23S ribosomal RNA"
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA large subunit methyltransferase"
                     /protein_id="NP_359635.1"
                     /db_xref="GI:15904085"
                     /db_xref="GeneID:933736"
     gene            2036394..2037587
                     /gene="sphtra"
                     /locus_tag="spr2045"
                     /db_xref="GeneID:934102"
     CDS             2036394..2037587
                     /gene="sphtra"
                     /locus_tag="spr2045"
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="NP_359636.1"
                     /db_xref="GI:15904086"
                     /db_xref="GeneID:934102"
     gene            2037645..2038403
                     /gene="spo0J"
                     /locus_tag="spr2046"
                     /db_xref="GeneID:933738"
     CDS             2037645..2038403
                     /gene="spo0J"
                     /locus_tag="spr2046"
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein"
                     /protein_id="NP_359637.1"
                     /db_xref="GI:15904087"
                     /db_xref="GeneID:933738"
ORIGIN      
//