Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.14861039 Released 2025-02-06 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: BONFERRONI Bonferroni count: 8995 GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (16) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) heme biosynthetic process (GO:0006783) 25 12 .02 + > 100 7.07E-30 heme a metabolic process (GO:0046160) 10 10 .01 + > 100 1.92E-29 heme A biosynthetic process (GO:0006784) 10 10 .01 + > 100 1.92E-29 porphyrin-containing compound biosynthetic process (GO:0006779) 29 12 .02 + > 100 7.05E-29 tetrapyrrole biosynthetic process (GO:0033014) 29 12 .02 + > 100 7.05E-29 pigment biosynthetic process (GO:0046148) 41 12 .03 + > 100 1.07E-26 heme metabolic process (GO:0042168) 41 12 .03 + > 100 1.07E-26 heme O biosynthetic process (GO:0048034) 9 9 .01 + > 100 5.65E-26 heme O metabolic process (GO:0048033) 9 9 .01 + > 100 5.65E-26 porphyrin-containing compound metabolic process (GO:0006778) 48 12 .04 + > 100 9.43E-26 tetrapyrrole metabolic process (GO:0033013) 57 12 .04 + > 100 9.56E-25 protoporphyrinogen IX metabolic process (GO:0046501) 11 9 .01 + > 100 3.10E-24 pigment metabolic process (GO:0042440) 65 12 .05 + > 100 5.44E-24 heme B biosynthetic process (GO:0006785) 8 8 .01 + > 100 1.45E-22 heme B metabolic process (GO:0046492) 8 8 .01 + > 100 1.45E-22 protoporphyrinogen IX biosynthetic process (GO:0006782) 9 8 .01 + > 100 1.31E-21 response to platinum ion (GO:0070541) 3 3 .00 + > 100 3.47E-06 biosynthetic process (GO:0009058) 3960 13 3.08 + 4.22 1.36E-03 erythrocyte differentiation (GO:0030218) 105 4 .08 + 49.00 9.99E-03 erythrocyte homeostasis (GO:0034101) 116 4 .09 + 44.35 1.49E-02 response to arsenic-containing substance (GO:0046685) 32 3 .02 + > 100 1.70E-02 response to methylmercury (GO:0051597) 4 2 .00 + > 100 3.06E-02 myeloid cell homeostasis (GO:0002262) 145 4 .11 + 35.48 3.62E-02 erythrocyte development (GO:0048821) 43 3 .03 + 89.74 4.20E-02