Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO molecular function complete Homo sapiens - REFLIST (20580) upload_1 (57) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) heparan sulfate 6-sulfotransferase activity (GO:0017095) 3 3 .01 + > 100 2.01E-08 7.30E-06 heparan sulfate N-deacetylase activity (GO:0102140) 3 3 .01 + > 100 2.01E-08 6.81E-06 N-acetylglucosamine deacetylase activity (GO:0050119) 3 3 .01 + > 100 2.01E-08 6.38E-06 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity (GO:0015018) 3 3 .01 + > 100 2.01E-08 6.01E-06 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity (GO:0050509) 2 2 .01 + > 100 7.54E-06 1.66E-03 heparan sulfate N-acetylglucosaminyltransferase activity (GO:0042328) 2 2 .01 + > 100 7.54E-06 1.59E-03 [heparan sulfate]-glucosamine 3-sulfotransferase activity (GO:0008467) 7 7 .02 + > 100 8.53E-19 8.65E-16 heparanase activity (GO:0030305) 2 2 .01 + > 100 7.54E-06 1.53E-03 protein xylosyltransferase activity (GO:0030158) 2 2 .01 + > 100 7.54E-06 1.47E-03 heparan sulfate sulfotransferase activity (GO:0034483) 15 15 .04 + > 100 5.76E-40 2.92E-36 heparan sulfate N-sulfotransferase activity (GO:0015016) 4 4 .01 + > 100 5.29E-11 3.83E-08 beta-galactosidase activity (GO:0004565) 5 4 .01 + > 100 2.64E-10 1.34E-07 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity (GO:0050508) 3 2 .01 + > 100 2.26E-05 4.24E-03 beta-glucuronidase activity (GO:0004566) 3 2 .01 + > 100 2.26E-05 4.09E-03 galactosidase activity (GO:0015925) 7 4 .02 + > 100 1.84E-09 7.77E-07 proteoglycan sulfotransferase activity (GO:0050698) 28 15 .08 + > 100 2.10E-32 5.34E-29 sulfotransferase activity (GO:0008146) 53 15 .15 + > 100 3.35E-27 5.66E-24 transferase activity, transferring sulphur-containing groups (GO:0016782) 70 15 .19 + 77.37 3.74E-25 4.74E-22 extracellular matrix structural constituent conferring compression resistance (GO:0030021) 22 4 .06 + 65.65 3.73E-07 9.45E-05 glucuronosyltransferase activity (GO:0015020) 34 5 .09 + 53.10 3.56E-08 1.00E-05 hyaluronic acid binding (GO:0005540) 24 3 .07 + 45.13 3.91E-05 6.61E-03 deacetylase activity (GO:0019213) 38 4 .11 + 38.01 3.64E-06 8.39E-04 hydrolase activity, hydrolyzing O-glycosyl compounds (GO:0004553) 91 9 .25 + 35.71 3.26E-12 2.75E-09 proteoglycan binding (GO:0043394) 37 3 .10 + 29.27 1.46E-04 2.12E-02 hydrolase activity, acting on glycosyl bonds (GO:0016798) 130 9 .36 + 25.00 8.43E-11 5.34E-08 UDP-glycosyltransferase activity (GO:0008194) 146 9 .40 + 22.26 2.39E-10 1.35E-07 extracellular matrix binding (GO:0050840) 66 4 .18 + 21.88 3.35E-05 5.86E-03 deacylase activity (GO:0160215) 69 4 .19 + 20.93 4.00E-05 6.54E-03 hexosyltransferase activity (GO:0016758) 197 7 .55 + 12.83 1.17E-06 2.82E-04 glycosyltransferase activity (GO:0016757) 267 9 .74 + 12.17 4.75E-08 1.27E-05 extracellular matrix structural constituent (GO:0005201) 168 5 .47 + 10.75 1.01E-04 1.56E-02 glycosaminoglycan binding (GO:0005539) 241 6 .67 + 8.99 5.34E-05 8.46E-03 transferase activity (GO:0016740) 2263 25 6.27 + 3.99 2.77E-10 1.28E-07 catalytic activity (GO:0003824) 5658 37 15.67 + 2.36 4.10E-09 1.60E-06 nucleic acid binding (GO:0003676) 3988 1 11.05 - .09 1.36E-04 2.02E-02