Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO cellular component complete Homo sapiens - REFLIST (20580) upload_1 (57) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) perineuronal net (GO:0072534) 10 3 .03 + > 100 2.38E-06 1.70E-04 lysosomal lumen (GO:0043202) 98 27 .27 + 99.47 4.93E-49 9.85E-46 perisynaptic extracellular matrix (GO:0098966) 11 3 .03 + 98.47 3.27E-06 2.25E-04 synapse-associated extracellular matrix (GO:0099535) 12 3 .03 + 90.26 4.35E-06 2.90E-04 Golgi lumen (GO:0005796) 106 20 .29 + 68.12 2.68E-32 1.34E-29 vacuolar lumen (GO:0005775) 177 27 .49 + 55.08 2.44E-41 2.44E-38 specialized extracellular matrix (GO:0140047) 22 3 .06 + 49.23 2.99E-05 1.87E-03 Golgi membrane (GO:0000139) 701 25 1.94 + 12.88 4.74E-22 1.05E-19 lytic vacuole (GO:0000323) 787 27 2.18 + 12.39 1.64E-23 5.45E-21 lysosome (GO:0005764) 787 27 2.18 + 12.39 1.64E-23 4.67E-21 vacuole (GO:0005773) 882 30 2.44 + 12.28 2.63E-26 1.05E-23 collagen-containing extracellular matrix (GO:0062023) 386 11 1.07 + 10.29 7.47E-09 8.78E-07 Golgi apparatus (GO:0005794) 1679 46 4.65 + 9.89 3.67E-40 2.44E-37 extracellular matrix (GO:0031012) 559 13 1.55 + 8.40 3.13E-09 4.16E-07 external encapsulating structure (GO:0030312) 560 13 1.55 + 8.38 3.19E-09 3.99E-07 cell surface (GO:0009986) 913 13 2.53 + 5.14 9.44E-07 8.20E-05 bounding membrane of organelle (GO:0098588) 2264 27 6.27 + 4.31 5.80E-12 1.16E-09 side of membrane (GO:0098552) 744 8 2.06 + 3.88 9.69E-04 4.50E-02 endomembrane system (GO:0012505) 4901 49 13.57 + 3.61 4.88E-23 1.22E-20 extracellular exosome (GO:0070062) 2102 15 5.82 + 2.58 4.52E-04 2.66E-02 extracellular vesicle (GO:1903561) 2131 15 5.90 + 2.54 5.24E-04 2.99E-02 extracellular space (GO:0005615) 3268 23 9.05 + 2.54 8.08E-06 5.21E-04 extracellular organelle (GO:0043230) 2132 15 5.90 + 2.54 5.26E-04 2.92E-02 extracellular membrane-bounded organelle (GO:0065010) 2132 15 5.90 + 2.54 5.26E-04 2.84E-02 organelle membrane (GO:0031090) 3855 27 10.68 + 2.53 8.07E-07 7.33E-05 extracellular region (GO:0005576) 4305 30 11.92 + 2.52 1.26E-07 1.26E-05 membrane (GO:0016020) 9822 48 27.20 + 1.76 1.34E-08 1.49E-06 organelle lumen (GO:0043233) 5759 28 15.95 + 1.76 9.19E-04 4.59E-02 intracellular organelle lumen (GO:0070013) 5759 28 15.95 + 1.76 9.19E-04 4.48E-02 membrane-enclosed lumen (GO:0031974) 5759 28 15.95 + 1.76 9.19E-04 4.37E-02 cytoplasm (GO:0005737) 12372 56 34.27 + 1.63 1.61E-11 2.93E-09 intracellular membrane-bounded organelle (GO:0043231) 12384 56 34.30 + 1.63 1.62E-11 2.70E-09 membrane-bounded organelle (GO:0043227) 13462 56 37.29 + 1.50 1.27E-09 1.96E-07 intracellular organelle (GO:0043229) 13488 56 37.36 + 1.50 1.34E-09 1.91E-07 organelle (GO:0043226) 14293 56 39.59 + 1.41 4.42E-08 4.65E-06 intracellular anatomical structure (GO:0005622) 15119 56 41.87 + 1.34 1.06E-06 8.83E-05 protein-containing complex (GO:0032991) 5943 4 16.46 - .24 9.39E-05 5.69E-03 nuclear lumen (GO:0031981) 4596 3 12.73 - .24 7.03E-04 3.69E-02 nucleus (GO:0005634) 7736 5 21.43 - .23 1.41E-06 1.04E-04 intracellular membraneless organelle (GO:0043232) 5463 1 15.13 - .07 1.06E-06 8.49E-05 membraneless organelle (GO:0043228) 5463 1 15.13 - .07 1.06E-06 8.16E-05 cytosol (GO:0005829) 5614 1 15.55 - .06 5.75E-07 5.47E-05 cytoskeleton (GO:0005856) 2545 0 7.05 - < 0.01 9.04E-04 4.63E-02