Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (57) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) heparan sulfate proteoglycan catabolic process (GO:0030200) 10 9 .03 + > 100 4.93E-23 4.56E-20 heparan sulfate proteoglycan biosynthetic process (GO:0015012) 30 23 .08 + > 100 1.73E-55 8.53E-52 heparan sulfate proteoglycan metabolic process (GO:0030201) 42 32 .12 + > 100 3.63E-78 5.38E-74 heparin proteoglycan biosynthetic process (GO:0030210) 11 8 .03 + > 100 3.40E-19 2.80E-16 heparin proteoglycan metabolic process (GO:0030202) 17 12 .05 + > 100 3.61E-28 4.45E-25 proteoglycan catabolic process (GO:0030167) 17 9 .05 + > 100 1.18E-19 1.03E-16 dermatan sulfate proteoglycan catabolic process (GO:0030209) 4 2 .01 + > 100 4.51E-05 1.08E-02 positive regulation of extracellular exosome assembly (GO:1903553) 4 2 .01 + > 100 4.51E-05 1.06E-02 galactose catabolic process (GO:0019388) 9 4 .02 + > 100 6.59E-09 3.62E-06 regulation of extracellular exosome assembly (GO:1903551) 6 2 .02 + > 100 1.12E-04 2.34E-02 proteoglycan biosynthetic process (GO:0030166) 78 26 .22 + > 100 1.15E-49 4.24E-46 proteoglycan metabolic process (GO:0006029) 106 35 .29 + > 100 4.81E-68 3.56E-64 glycosaminoglycan biosynthetic process (GO:0006024) 40 13 .11 + > 100 1.47E-24 1.55E-21 galactose metabolic process (GO:0006012) 13 4 .04 + > 100 3.71E-08 1.90E-05 dermatan sulfate proteoglycan metabolic process (GO:0050655) 13 4 .04 + > 100 3.71E-08 1.83E-05 aminoglycan biosynthetic process (GO:0006023) 48 13 .13 + 97.79 2.32E-23 2.29E-20 chondroitin sulfate proteoglycan biosynthetic process (GO:0050650) 24 6 .07 + 90.26 4.46E-11 2.87E-08 glycosaminoglycan metabolic process (GO:0030203) 77 19 .21 + 89.09 3.97E-33 5.88E-30 glycoprotein catabolic process (GO:0006516) 37 9 .10 + 87.82 5.79E-16 4.52E-13 chondroitin sulfate proteoglycan metabolic process (GO:0050654) 30 7 .08 + 84.25 1.65E-12 1.11E-09 dermatan sulfate proteoglycan biosynthetic process (GO:0050651) 9 2 .02 + 80.23 2.68E-04 4.90E-02 aminoglycan metabolic process (GO:0006022) 92 19 .25 + 74.57 1.74E-31 2.35E-28 sulfur compound catabolic process (GO:0044273) 47 9 .13 + 69.14 6.21E-15 4.60E-12 sulfur compound biosynthetic process (GO:0044272) 149 25 .41 + 60.58 3.08E-39 6.53E-36 glycosaminoglycan catabolic process (GO:0006027) 26 4 .07 + 55.55 7.55E-07 3.50E-04 sulfation (GO:0051923) 21 3 .06 + 51.58 2.59E-05 7.23E-03 aminoglycan catabolic process (GO:0006026) 32 4 .09 + 45.13 1.79E-06 7.60E-04 polysaccharide biosynthetic process (GO:0000271) 25 3 .07 + 43.33 4.44E-05 1.10E-02 sulfur compound metabolic process (GO:0006790) 314 34 .87 + 39.09 1.09E-47 2.69E-44 glycoprotein metabolic process (GO:0009100) 348 35 .96 + 36.31 4.26E-48 1.26E-44 glycoprotein biosynthetic process (GO:0009101) 281 26 .78 + 33.41 8.52E-34 1.58E-30 motor behavior (GO:0061744) 34 3 .09 + 31.86 1.13E-04 2.33E-02 hexose catabolic process (GO:0019320) 51 4 .14 + 28.32 1.20E-05 3.86E-03 ureteric bud morphogenesis (GO:0060675) 55 4 .15 + 26.26 1.62E-05 4.91E-03 monosaccharide catabolic process (GO:0046365) 55 4 .15 + 26.26 1.62E-05 4.81E-03 mesonephric tubule morphogenesis (GO:0072171) 56 4 .16 + 25.79 1.74E-05 5.07E-03 branching involved in ureteric bud morphogenesis (GO:0001658) 45 3 .12 + 24.07 2.63E-04 4.87E-02 nephron tubule morphogenesis (GO:0072078) 66 4 .18 + 21.88 3.35E-05 9.20E-03 nephron epithelium morphogenesis (GO:0072088) 68 4 .19 + 21.24 3.77E-05 9.98E-03 ureteric bud development (GO:0001657) 86 5 .24 + 20.99 4.00E-06 1.44E-03 mesonephric tubule development (GO:0072164) 87 5 .24 + 20.75 4.23E-06 1.46E-03 mesonephric epithelium development (GO:0072163) 87 5 .24 + 20.75 4.23E-06 1.43E-03 nephron morphogenesis (GO:0072028) 70 4 .19 + 20.63 4.23E-05 1.08E-02 renal tubule morphogenesis (GO:0061333) 71 4 .20 + 20.34 4.47E-05 1.09E-02 mesonephros development (GO:0001823) 91 5 .25 + 19.84 5.28E-06 1.74E-03 nephron tubule development (GO:0072080) 83 4 .23 + 17.40 8.26E-05 1.83E-02 carbohydrate derivative biosynthetic process (GO:1901137) 556 26 1.54 + 16.88 5.25E-26 5.98E-23 nephron epithelium development (GO:0072009) 109 5 .30 + 16.56 1.28E-05 4.03E-03 kidney morphogenesis (GO:0060993) 88 4 .24 + 16.41 1.04E-04 2.23E-02 renal tubule development (GO:0061326) 89 4 .25 + 16.23 1.08E-04 2.29E-02 carbohydrate derivative catabolic process (GO:1901136) 207 9 .57 + 15.70 5.25E-09 2.99E-06 kidney epithelium development (GO:0072073) 139 6 .38 + 15.59 2.33E-06 9.08E-04 smoothened signaling pathway (GO:0007224) 95 4 .26 + 15.20 1.40E-04 2.83E-02 carbohydrate derivative metabolic process (GO:1901135) 895 35 2.48 + 14.12 1.62E-33 2.66E-30 nephron development (GO:0072006) 140 5 .39 + 12.89 4.27E-05 1.07E-02 protein glycosylation (GO:0006486) 218 7 .60 + 11.59 2.29E-06 9.43E-04 macromolecule glycosylation (GO:0043413) 218 7 .60 + 11.59 2.29E-06 9.18E-04 regulation of protein localization to membrane (GO:1905475) 201 6 .56 + 10.78 1.93E-05 5.50E-03 glycosylation (GO:0070085) 238 7 .66 + 10.62 4.09E-06 1.44E-03 carbohydrate metabolic process (GO:0005975) 442 13 1.22 + 10.62 1.80E-10 1.11E-07 kidney development (GO:0001822) 306 6 .85 + 7.08 1.97E-04 3.80E-02 renal system development (GO:0072001) 317 6 .88 + 6.83 2.39E-04 4.54E-02 epithelial tube morphogenesis (GO:0060562) 317 6 .88 + 6.83 2.39E-04 4.48E-02 tube morphogenesis (GO:0035239) 700 11 1.94 + 5.67 2.89E-06 1.07E-03 skeletal system development (GO:0001501) 514 8 1.42 + 5.62 8.08E-05 1.81E-02 morphogenesis of an epithelium (GO:0002009) 464 7 1.29 + 5.45 2.83E-04 4.99E-02 cell migration (GO:0016477) 941 13 2.61 + 4.99 1.32E-06 5.94E-04 tissue morphogenesis (GO:0048729) 580 8 1.61 + 4.98 1.86E-04 3.62E-02 protein catabolic process (GO:0030163) 799 10 2.21 + 4.52 6.07E-05 1.40E-02 tube development (GO:0035295) 929 11 2.57 + 4.28 4.10E-05 1.07E-02 cell motility (GO:0048870) 1172 13 3.25 + 4.00 1.45E-05 4.48E-03 protein metabolic process (GO:0019538) 3342 35 9.26 + 3.78 1.67E-14 1.18E-11 macromolecule biosynthetic process (GO:0009059) 2937 27 8.13 + 3.32 2.32E-09 1.38E-06 anatomical structure morphogenesis (GO:0009653) 2270 17 6.29 + 2.70 9.17E-05 2.00E-02 biosynthetic process (GO:0009058) 3997 27 11.07 + 2.44 1.69E-06 7.35E-04 macromolecule metabolic process (GO:0043170) 5404 35 14.97 + 2.34 2.45E-08 1.30E-05 system development (GO:0048731) 3629 23 10.05 + 2.29 6.19E-05 1.41E-02 multicellular organism development (GO:0007275) 4029 24 11.16 + 2.15 1.40E-04 2.80E-02 primary metabolic process (GO:0044238) 6778 39 18.77 + 2.08 4.77E-08 2.28E-05 metabolic process (GO:0008152) 7642 39 21.17 + 1.84 2.71E-06 1.03E-03 cellular process (GO:0009987) 15563 55 43.10 + 1.28 3.58E-05 9.65E-03 regulation of gene expression (GO:0010468) 4908 3 13.59 - .22 2.80E-04 4.99E-02 regulation of macromolecule biosynthetic process (GO:0010556) 5014 3 13.89 - .22 2.71E-04 4.90E-02 regulation of biosynthetic process (GO:0009889) 5195 3 14.39 - .21 1.68E-04 3.32E-02