LOCUS       NC_001133             230218 bp    DNA     linear   CON 06-APR-2018
DEFINITION  Saccharomyces cerevisiae S288C chromosome I, complete sequence.
ACCESSION   NC_001133
VERSION     NC_001133.9
DBLINK      BioProject: PRJNA128
            Assembly: GCF_000146045.2
KEYWORDS    RefSeq.
SOURCE      Saccharomyces cerevisiae S288C
  ORGANISM  Saccharomyces cerevisiae S288C
            Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina;
            Saccharomycetes; Saccharomycetales; Saccharomycetaceae;
            Saccharomyces.
REFERENCE   1  (bases 1 to 230218)
  AUTHORS   Goffeau,A., Barrell,B.G., Bussey,H., Davis,R.W., Dujon,B.,
            Feldmann,H., Galibert,F., Hoheisel,J.D., Jacq,C., Johnston,M.,
            Louis,E.J., Mewes,H.W., Murakami,Y., Philippsen,P., Tettelin,H. and
            Oliver,S.G.
  TITLE     Life with 6000 genes
  JOURNAL   Science 274 (5287), 546 (1996)
   PUBMED   8849441
REFERENCE   2  (bases 1 to 230218)
  AUTHORS   Bussey,H., Kaback,D.B., Zhong,W., Vo,D.T., Clark,M.W., Fortin,N.,
            Hall,J., Ouellette,B.F., Keng,T., Barton,A.B. et al.
  TITLE     The nucleotide sequence of chromosome I from Saccharomyces
            cerevisiae
  JOURNAL   Proc. Natl. Acad. Sci. U.S.A. 92 (9), 3809-3813 (1995)
   PUBMED   7731988
REFERENCE   3  (bases 1 to 230218)
  CONSRTM   NCBI Genome Project
  TITLE     Direct Submission
  JOURNAL   Submitted (04-APR-2018) National Center for Biotechnology
            Information, NIH, Bethesda, MD 20894, USA
REFERENCE   4  (bases 1 to 230218)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (31-MAR-2011) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
  REMARK    Sequence update by submitter
REFERENCE   5  (bases 1 to 230218)
  CONSRTM   Saccharomyces Genome Database
  TITLE     Direct Submission
  JOURNAL   Submitted (11-DEC-2009) Department of Genetics, Stanford
            University, Stanford, CA 94305-5120, USA
COMMENT     REVIEWED REFSEQ: This record has been curated by SGD. The reference
            sequence is identical to BK006935.
            On Apr 26, 2011 this sequence version replaced NC_001133.8.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider :: SGD
            Annotation Status   :: Full Annotation
            Annotation Version  :: R64-2-1
            URL                 :: http://www.yeastgenome.org/
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..230218
                     /organism="Saccharomyces cerevisiae S288C"
                     /mol_type="genomic DNA"
                     /strain="S288C"
                     /db_xref="taxon:559292"
                     /chromosome="I"
     telomere        complement(1..801)
                     /note="TEL01L; Telomeric region on the left arm of
                     Chromosome I; composed of an X element core sequence, X
                     element combinatorial repeats, and a short terminal
                     stretch of telomeric repeats"
                     /db_xref="SGD:S000028862"
     rep_origin      707..776
                     /note="ARS102;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121252"
     gene            complement(<1807..>2169)
                     /gene="PAU8"
                     /locus_tag="YAL068C"
                     /db_xref="GeneID:851229"
     mRNA            complement(<1807..>2169)
                     /gene="PAU8"
                     /locus_tag="YAL068C"
                     /product="seripauperin PAU8"
                     /transcript_id="NM_001180043.1"
                     /db_xref="GeneID:851229"
     CDS             complement(1807..2169)
                     /gene="PAU8"
                     /locus_tag="YAL068C"
                     /note="hypothetical protein; member of the seripauperin
                     multigene family encoded mainly in subtelomeric regions"
                     /codon_start=1
                     /product="seripauperin PAU8"
                     /protein_id="NP_009332.1"
                     /db_xref="GeneID:851229"
                     /db_xref="SGD:S000002142"
                     /translation="MVKLTSIAAGVAAIAATASATTTLAQSDERVNLVELGVYVSDIR
                     AHLAQYYMFQAAHPTETYPVEVAEAVFNYGDFTTMLTGIAPDQVTRMITGVPWYSSRL
                     KPAISSALSKDGIYTIAN"
     gene            <2480..>2707
                     /locus_tag="YAL067W-A"
                     /db_xref="GeneID:1466426"
     mRNA            <2480..>2707
                     /locus_tag="YAL067W-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184582.1"
                     /db_xref="GeneID:1466426"
     CDS             2480..2707
                     /locus_tag="YAL067W-A"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878038.1"
                     /db_xref="GeneID:1466426"
                     /db_xref="SGD:S000028593"
                     /translation="MPIIGVPRCLIKPFSVPVTFPFSVKKNIRILDLDPRTEAYCLSL
                     NSVCFKRLPRRKYFHLLNSYNIKRVLGVVYC"
     gene            complement(<7235..>9016)
                     /gene="SEO1"
                     /locus_tag="YAL067C"
                     /db_xref="GeneID:851230"
     mRNA            complement(<7235..>9016)
                     /gene="SEO1"
                     /locus_tag="YAL067C"
                     /product="putative permease SEO1"
                     /transcript_id="NM_001178208.1"
                     /db_xref="GeneID:851230"
     CDS             complement(7235..9016)
                     /gene="SEO1"
                     /locus_tag="YAL067C"
                     /note="Putative permease; member of the allantoate
                     transporter subfamily of the major facilitator
                     superfamily; mutation confers resistance to ethionine
                     sulfoxide"
                     /codon_start=1
                     /product="putative permease SEO1"
                     /protein_id="NP_009333.1"
                     /db_xref="GeneID:851230"
                     /db_xref="SGD:S000000062"
                     /translation="MYSIVKEIIVDPYKRLKWGFIPVKRQVEDLPDDLNSTEIVTISN
                     SIQSHETAENFITTTSEKDQLHFETSSYSEHKDNVNVTRSYEYRDEADRPWWRFFDEQ
                     EYRINEKERSHNKWYSWFKQGTSFKEKKLLIKLDVLLAFYSCIAYWVKYLDTVNINNA
                     YVSGMKEDLGFQGNDLVHTQVMYTVGNIIFQLPFLIYLNKLPLNYVLPSLDLCWSLLT
                     VGAAYVNSVPHLKAIRFFIGAFEAPSYLAYQYLFGSFYKHDEMVRRSAFYYLGQYIGI
                     LSAGGIQSAVYSSLNGVNGLEGWRWNFIIDAIVSVVVGLIGFYSLPGDPYNCYSIFLT
                     DDEIRLARKRLKENQTGKSDFETKVFDIKLWKTIFSDWKIYILTLWNIFCWNDSNVSS
                     GAYLLWLKSLKRYSIPKLNQLSMITPGLGMVYLMLTGIIADKLHSRWFAIIFTQVFNI
                     IGNSILAAWDVAEGAKWFAFMLQCFGWAMAPVLYSWQNDICRRDAQTRAITLVTMNIM
                     AQSSTAWISVLVWKTEEAPRYLKGFTFTACSAFCLSIWTFVVLYFYKRDERNNAKKNG
                     IVLYNSKHGVEKPTSKDVETLSVSDEK"
     rep_origin      7997..8547
                     /note="ARS103;
                     Autonomously Replicating Sequence; replication origin of
                     very weak function"
                     /db_xref="SGD:S000121253"
     gene            complement(<11565..>11951)
                     /locus_tag="YAL065C"
                     /db_xref="GeneID:851232"
     mRNA            complement(<11565..>11951)
                     /locus_tag="YAL065C"
                     /product="hypothetical protein"
                     /transcript_id="NM_001179897.1"
                     /db_xref="GeneID:851232"
     CDS             complement(11565..11951)
                     /locus_tag="YAL065C"
                     /note="hypothetical protein; shows sequence similarity to
                     FLO1 and other flocculins"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009335.1"
                     /db_xref="GeneID:851232"
                     /db_xref="SGD:S000001817"
                     /translation="MNSATSETTTNTGAAETTTSTGAAETKTVVTSSISRFNHAETQT
                     ASATDVIGHSSSVVSVSETGNTKSLITSGLSTMSQQPRSTPASSIIGSSTASLEISTY
                     VGIANGLLTNNGISVFISTVLLAIVW"
     gene            <12046..>12426
                     /locus_tag="YAL064W-B"
                     /db_xref="GeneID:851233"
     mRNA            <12046..>12426
                     /locus_tag="YAL064W-B"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180042.1"
                     /db_xref="GeneID:851233"
     CDS             12046..12426
                     /locus_tag="YAL064W-B"
                     /note="Fungal-specific hypothetical protein"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009336.1"
                     /db_xref="GeneID:851233"
                     /db_xref="SGD:S000002141"
                     /translation="MAGEAVSEHTPDSQEVTVTSVVCCLDSVVEIGHHVVYSVVTPLI
                     VAVLIDTMAGEAVLEHTSDSQEEIVTTVVCSVVPLVCFVVSVVCFVISVVEIGHHVVY
                     SVVAPLTVTVAVETIAEEMDSVHT"
     gene            complement(<13363..>13743)
                     /gene="TDA8"
                     /locus_tag="YAL064C-A"
                     /gene_synonym="YAL065C-A"
                     /db_xref="GeneID:851234"
     mRNA            complement(<13363..>13743)
                     /gene="TDA8"
                     /locus_tag="YAL064C-A"
                     /gene_synonym="YAL065C-A"
                     /product="Tda8p"
                     /transcript_id="NM_001180041.1"
                     /db_xref="GeneID:851234"
     CDS             complement(13363..13743)
                     /gene="TDA8"
                     /locus_tag="YAL064C-A"
                     /gene_synonym="YAL065C-A"
                     /note="hypothetical protein; null mutant is sensitive to
                     expression of the top1-T722A allele; not an essential
                     gene"
                     /codon_start=1
                     /product="Tda8p"
                     /protein_id="NP_058136.1"
                     /db_xref="GeneID:851234"
                     /db_xref="SGD:S000002140"
                     /translation="MTGYFLPPQTSSYTFRFAKVDDSAILSVGGDVAFGCCAQEQPPI
                     TSTNFTINGIKPWQGRLPDNIAGTVYMYAGFYCPMKIVYSNAVSWHTLPVSVELPDVT
                     TVSDDFAGHVYSFDDDLTAQLYYP"
     gene            <21566..>21850
                     /locus_tag="YAL064W"
                     /db_xref="GeneID:851235"
     mRNA            <21566..>21850
                     /locus_tag="YAL064W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001178206.2"
                     /db_xref="GeneID:851235"
     CDS             21566..21850
                     /locus_tag="YAL064W"
                     /note="hypothetical protein; may interact with ribosomes,
                     based on co-purification experiments"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009337.2"
                     /db_xref="GeneID:851235"
                     /db_xref="SGD:S000000060"
                     /translation="MNPFASLEGQDNISSVFFLHMQQFESQVKDRFRFPIFRLERKTF
                     GNSCYQVETLKVKCRPRHAKSCNLLTLLFKSRTQSVLVPNFGFLILNSEP"
     repeat_region   22230..22552
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006787"
     gene            complement(<22395..>22685)
                     /locus_tag="YAL063C-A"
                     /db_xref="GeneID:1466427"
     mRNA            complement(<22395..>22685)
                     /locus_tag="YAL063C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184642.1"
                     /db_xref="GeneID:1466427"
     CDS             complement(22395..22685)
                     /locus_tag="YAL063C-A"
                     /note="hypothetical protein; identified by expression
                     profiling and mass spectrometry"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878039.1"
                     /db_xref="GeneID:1466427"
                     /db_xref="SGD:S000028813"
                     /translation="MCPRTVLLIININHWFYDKNIVRIILTFRLDSGHISDICFINKN
                     LANALITADISLLKRHDIRCTKYIITYYQRYRNKEKGKFISLCKNTIISSSV"
     gene            complement(<24000..>27968)
                     /gene="FLO9"
                     /locus_tag="YAL063C"
                     /db_xref="GeneID:851236"
     mRNA            complement(<24000..>27968)
                     /gene="FLO9"
                     /locus_tag="YAL063C"
                     /product="flocculin FLO9"
                     /transcript_id="NM_001178205.1"
                     /db_xref="GeneID:851236"
     CDS             complement(24000..27968)
                     /gene="FLO9"
                     /locus_tag="YAL063C"
                     /note="Lectin-like protein with similarity to Flo1p;
                     thought to be expressed and involved in flocculation"
                     /codon_start=1
                     /product="flocculin FLO9"
                     /protein_id="NP_009338.1"
                     /db_xref="GeneID:851236"
                     /db_xref="SGD:S000000059"
                     /translation="MSLAHYCLLLAIVTLLGLTNVVSATTAACLPANSRKNGMNVNFY
                     QYSLRDSSTYSNAAYMAYGYASKTKLGSVGGQTDISIDYNIPCVSSSGTFPCPQEDLY
                     GNWGCKGIGACSNNPIIAYWSTDLFGFYTTPTNVTLEMTGYFLPPQTGSYTFKFATVD
                     DSAILSVGGSIAFECCAQEQPPITSTNFTINGIKPWNGSPPDNITGTVYMYAGFYYPM
                     KIVYSNAVAWGTLPISVTLPDGTTVSDDFEGYVYTFDNNLSQPNCTIPDPSNYTVSTT
                     ITTTEPWTGTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTTASTIITTTEPWNSTFTS
                     TSTELTTVTGTNGVRTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTELTTVTGTNG
                     LPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTP
                     TTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPW
                     NDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTEMTT
                     VTGTNGLPTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTEMTTVTGTNGLPTDETI
                     IVIRTPTTATTAITTTQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAM
                     TTTQPWNDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTST
                     STEMTTVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQ
                     PTDETVIVIRTPTSEGLVTTTTEPWTGTFTSTSTEMTTITGTNGQPTDETVIIVKTPT
                     TAISSSLSSSSGQITSFITSARPIITPFYPSNGTSVISSSVISSSDTSSLVISSSVTS
                     SLVTSSPVISSSFISSPVISSTTTSASILSESSKSSVIPTSSSTSGSSESETGSASSA
                     SSSSSISSESPKSTYSSSSLPPVTSATTSQEITSSLPPVTTTKTSEQTTLVTVTSCES
                     HVCTESISSAIVSTATVTVSGATTEYTTWCPISTTEITKQTTETTKQTKGTTEQTTET
                     TKQTTVVTISSCESDVCSKTASPAIVSTSTATINGVTTEYTTWCPISTTESKQQTTLV
                     TVTSCGSGVCSETTSPAIVSTATATVNDVVTVYSTWRPQTTNEQSVSSKMNSATSETT
                     TNTGAAETTTSTGAAETKTVVTSSISRFNHAETQTASATDVIGHSSSVVSVSETGNTK
                     SLTSSGLSTMSQQPRSTPASSMVGSSTASLEISTYAGSANSLLAGSGLSVFIASLLLA
                     II"
     rep_origin      30946..31183
                     /note="ARS104;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118317"
     gene            <31567..>32940
                     /gene="GDH3"
                     /locus_tag="YAL062W"
                     /gene_synonym="FUN51"
                     /db_xref="GeneID:851237"
     mRNA            <31567..>32940
                     /gene="GDH3"
                     /locus_tag="YAL062W"
                     /gene_synonym="FUN51"
                     /product="glutamate dehydrogenase (NADP(+)) GDH3"
                     /transcript_id="NM_001178204.1"
                     /db_xref="GeneID:851237"
     CDS             31567..32940
                     /gene="GDH3"
                     /locus_tag="YAL062W"
                     /gene_synonym="FUN51"
                     /EC_number="1.4.1.4"
                     /note="NADP(+)-dependent glutamate dehydrogenase;
                     synthesizes glutamate from ammonia and
                     alpha-ketoglutarate; rate of alpha-ketoglutarate
                     utilization differs from Gdh1p; expression regulated by
                     nitrogen and carbon sources; GDH3 has a paralog, GDH1,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="glutamate dehydrogenase (NADP(+)) GDH3"
                     /protein_id="NP_009339.1"
                     /db_xref="GeneID:851237"
                     /db_xref="SGD:S000000058"
                     /translation="MTSEPEFQQAYDEIVSSVEDSKIFEKFPQYKKVLPIVSVPERII
                     QFRVTWENDNGEQEVAQGYRVQFNSAKGPYKGGLRFHPSVNLSILKFLGFEQIFKNAL
                     TGLDMGGGKGGLCVDLKGKSDNEIRRICYAFMRELSRHIGKDTDVPAGDIGVGGREIG
                     YLFGAYRSYKNSWEGVLTGKGLNWGGSLIRPEATGFGLVYYTQAMIDYATNGKESFEG
                     KRVTISGSGNVAQYAALKVIELGGIVVSLSDSKGCIISETGITSEQIHDIASAKIRFK
                     SLEEIVDEYSTFSESKMKYVAGARPWTHVSNVDIALPCATQNEVSGDEAKALVASGVK
                     FVAEGANMGSTPEAISVFETARSTATNAKDAVWFGPPKAANLGGVAVSGLEMAQNSQK
                     VTWTAERVDQELKKIMINCFNDCIQAAQEYSTEKNTNTLPSLVKGANIASFVMVADAM
                     LDQGDVF"
     gene            <33448..>34701
                     /gene="BDH2"
                     /locus_tag="YAL061W"
                     /db_xref="GeneID:851238"
     mRNA            <33448..>34701
                     /gene="BDH2"
                     /locus_tag="YAL061W"
                     /product="putative dehydrogenase BDH2"
                     /transcript_id="NM_001178203.1"
                     /db_xref="GeneID:851238"
     CDS             33448..34701
                     /gene="BDH2"
                     /locus_tag="YAL061W"
                     /EC_number="1.1.1.303"
                     /note="Putative medium-chain alcohol dehydrogenase with
                     similarity to BDH1; transcription induced by
                     constitutively active PDR1 and PDR3"
                     /codon_start=1
                     /product="putative dehydrogenase BDH2"
                     /protein_id="NP_009340.1"
                     /db_xref="GeneID:851238"
                     /db_xref="SGD:S000000057"
                     /translation="MRALAYFGKGNIRFTNHLKEPHIVAPDELVIDIEWCGICGTDLH
                     EYTDGPIFFPEDGHTHEISHNPLPQAMGHEMAGTVLEVGPGVKNLKVGDKVVVEPTGT
                     CRDRYRWPLSPNVDKEWCAACKKGYYNICSYLGLCGAGVQSGGFAERVVMNESHCYKV
                     PDFVPLDVAALIQPLAVCWHAIRVCEFKAGSTALIIGAGPIGLGTILALNAAGCKDIV
                     VSEPAKVRRELAEKMGARVYDPTAHAAKESIDYLRSIADGGDGFDYTFDCSGLEVTLN
                     AAIQCLTFRGTAVNLAMWGHHKIQFSPMDITLHERKYTGSMCYTHHDFEAVIEALEEG
                     RIDIDRARHMITGRVNIEDGLDGAIMKLINEKESTIKIILTPNNHGELNREADNEKKE
                     ISELSSRKDQERLRESINEAKLRHT"
     gene            <35155..>36303
                     /gene="BDH1"
                     /locus_tag="YAL060W"
                     /db_xref="GeneID:851239"
     mRNA            <35155..>36303
                     /gene="BDH1"
                     /locus_tag="YAL060W"
                     /product="(R,R)-butanediol dehydrogenase"
                     /transcript_id="NM_001178202.2"
                     /db_xref="GeneID:851239"
     CDS             35155..36303
                     /gene="BDH1"
                     /locus_tag="YAL060W"
                     /EC_number="1.1.1.4"
                     /note="NAD-dependent (R,R)-butanediol dehydrogenase;
                     catalyzes oxidation of (R,R)-2,3-butanediol to
                     (3R)-acetoin, oxidation of meso-butanediol to
                     (3S)-acetoin, and reduction of acetoin; enhances use of
                     2,3-butanediol as an aerobic carbon source"
                     /codon_start=1
                     /product="(R,R)-butanediol dehydrogenase"
                     /protein_id="NP_009341.2"
                     /db_xref="GeneID:851239"
                     /db_xref="SGD:S000000056"
                     /translation="MRALAYFKKGDIHFTNDIPRPEIQTDDEVIIDVSWCGICGSDLH
                     EYLDGPIFMPKDGECHKLSNAALPLAMGHEMSGIVSKVGPKVTKVKVGDHVVVDAASS
                     CADLHCWPHSKFYNSKPCDACQRGSENLCTHAGFVGLGVISGGFAEQVVVSQHHIIPV
                     PKEIPLDVAALVEPLSVTWHAVKISGFKKGSSALVLGAGPIGLCTILVLKGMGASKIV
                     VSEIAERRIEMAKKLGVEVFNPSKHGHKSIEILRGLTKSHDGFDYSYDCSGIQVTFET
                     SLKALTFKGTATNIAVWGPKPVPFQPMDVTLQEKVMTGSIGYVVEDFEEVVRAIHNGD
                     IAMEDCKQLITGKQRIEDGWEKGFQELMDHKESNVKILLTPNNHGEMK"
     gene            <36509..>37147
                     /gene="ECM1"
                     /locus_tag="YAL059W"
                     /db_xref="GeneID:851240"
     mRNA            <36509..>37147
                     /gene="ECM1"
                     /locus_tag="YAL059W"
                     /product="Ecm1p"
                     /transcript_id="NM_001178201.2"
                     /db_xref="GeneID:851240"
     CDS             36509..37147
                     /gene="ECM1"
                     /locus_tag="YAL059W"
                     /note="Pre-ribosomal factor involved in 60S ribosomal
                     protein subunit export; associates with the pre-60S
                     particle; shuttles between the nucleus and cytoplasm"
                     /codon_start=1
                     /product="Ecm1p"
                     /protein_id="NP_009342.2"
                     /db_xref="GeneID:851240"
                     /db_xref="SGD:S000000055"
                     /translation="MWEQRRQKVVFSLTILVRYRLKQSMAKKISKNSRAARQSDALEP
                     EVKDLSELPRAEKTDLTNILIRTAAKNEALLEAKISKKANKSKRGKKLNKKALEDKLA
                     NSISSMDRDRLVKALNFTNRLDGKIAKSISRAKYIQNTRKAGWDSTNETIKKELAFLN
                     GGLSVQAKSASEGNAEKEDEEIPEVFDSLAEDNTVQKTPTNRFGVLPDDVEE"
     gene            <37464..>38972
                     /gene="CNE1"
                     /locus_tag="YAL058W"
                     /gene_synonym="FUN48"
                     /db_xref="GeneID:851241"
     mRNA            <37464..>38972
                     /gene="CNE1"
                     /locus_tag="YAL058W"
                     /gene_synonym="FUN48"
                     /product="calnexin"
                     /transcript_id="NM_001178200.1"
                     /db_xref="GeneID:851241"
     CDS             37464..38972
                     /gene="CNE1"
                     /locus_tag="YAL058W"
                     /gene_synonym="FUN48"
                     /note="Calnexin; integral membrane ER chaperone involved
                     in folding and quality control of glycoproteins; chaperone
                     activity is inhibited by Mpd1p, with which Cne1p
                     interacts; 24% identical to mammalian calnexin; Ca+
                     binding not yet shown in yeast"
                     /codon_start=1
                     /product="calnexin"
                     /protein_id="NP_009343.1"
                     /db_xref="GeneID:851241"
                     /db_xref="SGD:S000000054"
                     /translation="MKFSAYLWWLFLNLALVKGTSLLSNVTLAEDSFWEHFQAYTNTK
                     HLNQEWITSEAVNNEGSKIYGAQWRLSQGRLQGSAWDKGIAVRTGNAAAMIGHLLETP
                     INVSETDTLVVQYEIKLDNSLTCGGAFIKLMSGFMNVEALKHYAPDTEGVELVFGPDY
                     CAPEINGVQFAINKVDKITHESKLRYLQEMPLSKLTDTSQSHLYTLIIDESAQSFQIL
                     IDGKTVMVREHIEDKKKVNFEPPITPPLMIPDVSVAKPHDWDDRIRIPDPEAVKLSDR
                     DERDPLMIPHPDGTEPPEWNSSIPEYILDPNAQKPSWWKELEHGEWIPPMIKNPLCTA
                     ERGCGQQIPGLINNAKYKGPGELNEIINPNYMGEWHPPEIENPLYYEEQHPLRIENVI
                     SGVILEFWSGSPNMLISNIYVGKNVTEAQIIGNKTWLMRDRAFRGSDGPTERKFMNSR
                     LGNLQTTFHNERESPNPFDRIIDRILEQPLKFVLTAAVVLLTTSVLCCVVFT"
     gene            <39259..>41901
                     /gene="GPB2"
                     /locus_tag="YAL056W"
                     /gene_synonym="KRH1"
                     /db_xref="GeneID:851243"
     mRNA            <39259..>41901
                     /gene="GPB2"
                     /locus_tag="YAL056W"
                     /gene_synonym="KRH1"
                     /product="Gpb2p"
                     /transcript_id="NM_001178199.2"
                     /db_xref="GeneID:851243"
     CDS             39259..41901
                     /gene="GPB2"
                     /locus_tag="YAL056W"
                     /gene_synonym="KRH1"
                     /note="Multistep regulator of cAMP-PKA signaling; inhibits
                     PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP
                     dependency; inhibits Ras activity through direct
                     interactions with Ira1p/2p; regulated by G-alpha protein
                     Gpa2p; GPB2 has a paralog, GPB1, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="Gpb2p"
                     /protein_id="NP_009345.3"
                     /db_xref="GeneID:851243"
                     /db_xref="SGD:S000000052"
                     /translation="MEISSSPWNDGGYSPYERNRVAVSPFSSALEGEERIETSRSLGD
                     HCFEPLPYVTNYLSIFALFGKEIFGDKGNVSSRNEYLLKKYYSLKKPFVLRHNGHALK
                     NPDMPLQRNDILQTNFMVDKFLNRTVRSVNFNNFKIISDMQSKSGRGTKSGTNQNQSA
                     DAIQNICLPSIPSALPYFQYYRKLLTVNTKEWDILKLHSLWVPKLRKDFKDFSLYGDK
                     NSLKPIDSHYDEDNTMKKNLFFERSPSRQTLDGKGCASKGYDISSGNMIIPSLFSEDK
                     LPALTYHCSVELNGNIYIFGGLMPCYSYEEDAPMLNDFFVDGIKNLPPPLLPQVINNP
                     SMVNNPHLYVASIPSCRFSKPKMGGYIPPPLLCVQGSKLTDRHIFFYGGFEIRTETRG
                     DENGKYHLKKRLYVNNTGYILDIMSFKFTKIDIIVQPSKYNAYPTMSSRFGHLQISID
                     NPNRRASVHSSSMNEIHKMGSASMKQGSSITSGRLEKAAVLSSLPHNTVHTVIIFGGY
                     RQTGDDRYEAMNDLWKIEIPVIRRGKKGYCKFSETANAILLTPSEKDKSDWPEERAFS
                     AFSVHGTSLMDRSSLDMRLLNNLKNHFVLKPSYISQDRVVSPKPVFPMMVHGTHQDLF
                     NSGSAAQESPKAGASASSASAASFDPDMDDNLENYIVNPGRKSSSIPMTAIGRQRLIL
                     SQEKPVGKTVVLHGGSNGLNVLDDMWLMDLECETWTPIETFAKADSSEDGDEKLDSVN
                     VGLVGHRMESIGRICVCIGGMVQEDVDQFYSENDDEPPRKRKVDTLPLGGNFLNTIDL
                     STQCWEEHKITLSKKEDDEDRQDSENEDTNSNIVVGVGGTSLQCDKSIILIGGLISRR
                     SNVKEIYLHGTITKSIFPSVNPSA"
     rep_origin      41992..42151
                     /note="ARS105;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121254"
     gene            <42177..>42719
                     /gene="PEX22"
                     /locus_tag="YAL055W"
                     /gene_synonym="YAF5"
                     /db_xref="GeneID:851244"
     mRNA            <42177..>42719
                     /gene="PEX22"
                     /locus_tag="YAL055W"
                     /gene_synonym="YAF5"
                     /product="ubiquitin-protein transferase activating protein
                     PEX22"
                     /transcript_id="NM_001178198.1"
                     /db_xref="GeneID:851244"
     CDS             42177..42719
                     /gene="PEX22"
                     /locus_tag="YAL055W"
                     /gene_synonym="YAF5"
                     /note="Putative peroxisomal membrane protein; required for
                     import of peroxisomal proteins; functionally complements a
                     Pichia pastoris pex22 mutation"
                     /codon_start=1
                     /product="ubiquitin-protein transferase activating protein
                     PEX22"
                     /protein_id="NP_009346.1"
                     /db_xref="GeneID:851244"
                     /db_xref="SGD:S000000051"
                     /translation="MPPPSRSRINKTRTLGIVGTAIAVLVTSYYIYQKVTSAKEDNGA
                     RPPEGDSVKENKKARKSKCIIMSKSIQGLPIKWEEYAADEVVLLVPTSHTDGSMKQAI
                     GDAFRKTKNEHKIIYCDSMDGLWSCVRRLGKFQCILNSRDFTSSGGSDAAVVPEDIGR
                     FVKFVVDSDVEDVLIDTLCN"
     gene            complement(<42881..>45022)
                     /gene="ACS1"
                     /locus_tag="YAL054C"
                     /gene_synonym="FUN44"
                     /db_xref="GeneID:851245"
     mRNA            complement(<42881..>45022)
                     /gene="ACS1"
                     /locus_tag="YAL054C"
                     /gene_synonym="FUN44"
                     /product="acetate--CoA ligase 1"
                     /transcript_id="NM_001178197.1"
                     /db_xref="GeneID:851245"
     CDS             complement(42881..45022)
                     /gene="ACS1"
                     /locus_tag="YAL054C"
                     /gene_synonym="FUN44"
                     /EC_number="6.2.1.1"
                     /note="Acetyl-coA synthetase isoform; along with Acs2p,
                     acetyl-coA synthetase isoform is the nuclear source of
                     acetyl-coA for histone acetylation; expressed during
                     growth on nonfermentable carbon sources and under aerobic
                     conditions"
                     /codon_start=1
                     /product="acetate--CoA ligase 1"
                     /protein_id="NP_009347.1"
                     /db_xref="GeneID:851245"
                     /db_xref="SGD:S000000050"
                     /translation="MSPSAVQSSKLEEQSSEIDKLKAKMSQSAATAQQKKEHEYEHLT
                     SVKIVPQRPISDRLQPAIATHYSPHLDGLQDYQRLHKESIEDPAKFFGSKATQFLNWS
                     KPFDKVFIPDPKTGRPSFQNNAWFLNGQLNACYNCVDRHALKTPNKKAIIFEGDEPGQ
                     GYSITYKELLEEVCQVAQVLTYSMGVRKGDTVAVYMPMVPEAIITLLAISRIGAIHSV
                     VFAGFSSNSLRDRINDGDSKVVITTDESNRGGKVIETKRIVDDALRETPGVRHVLVYR
                     KTNNPSVAFHAPRDLDWATEKKKYKTYYPCTPVDSEDPLFLLYTSGSTGAPKGVQHST
                     AGYLLGALLTMRYTFDTHQEDVFFTAGDIGWITGHTYVVYGPLLYGCATLVFEGTPAY
                     PNYSRYWDIIDEHKVTQFYVAPTALRLLKRAGDSYIENHSLKSLRCLGSVGEPIAAEV
                     WEWYSEKIGKNEIPIVDTYWQTESGSHLVTPLAGGVTPMKPGSASFPFFGIDAVVLDP
                     NTGEELNTSHAEGVLAVKAAWPSFARTIWKNHDRYLDTYLNPYPGYYFTGDGAAKDKD
                     GYIWILGRVDDVVNVSGHRLSTAEIEAAIIEDPIVAECAVVGFNDDLTGQAVAAFVVL
                     KNKSSWSTATDDELQDIKKHLVFTVRKDIGPFAAPKLIILVDDLPKTRSGKIMRRILR
                     KILAGESDQLGDVSTLSNPGIVRHLIDSVKL"
     gene            <45899..>48250
                     /gene="FLC2"
                     /locus_tag="YAL053W"
                     /db_xref="GeneID:851246"
     mRNA            <45899..>48250
                     /gene="FLC2"
                     /locus_tag="YAL053W"
                     /product="flavin adenine dinucleotide transporter FLC2"
                     /transcript_id="NM_001178196.2"
                     /db_xref="GeneID:851246"
     CDS             45899..48250
                     /gene="FLC2"
                     /locus_tag="YAL053W"
                     /note="Putative calcium channel involved in calcium
                     release under hypotonic stress; required for uptake of FAD
                     into endoplasmic reticulum; involved in cell wall
                     maintenance; FLC2 has a paralog, YOR365C, that arose from
                     the whole genome duplication"
                     /codon_start=1
                     /product="flavin adenine dinucleotide transporter FLC2"
                     /protein_id="NP_009348.2"
                     /db_xref="GeneID:851246"
                     /db_xref="SGD:S000000049"
                     /translation="MIFLNTFARCLLTCFVLCSGTARSSDTNDTTPASAKHLQTTSLL
                     TCMDNSQLTASFFDVKFYPDNNTVIFDIDATTTLNGNVTVKAELLTYGLKVLDKTFDL
                     CSLGQVSLCPLSAGRIDVMSTQVIESSITKQFPGIAYTIPDLDAQVRVVAYAQNDTEF
                     ETPLACVQAILSNGKTVQTKYAAWPIAAISGVGVLTSGFVSVIGYSATAAHIASNSIS
                     LFIYFQNLAITAMMGVSRVPPIAAAWTQNFQWSMGIINTNFMQKIFDWYVQATNGVSN
                     VVVANKDVLSISVQKRAISMASSSDYNFDTILDDSNLYTTSEKDPSNYSAKILVLRGI
                     ERVAYLANIELSNFFLTGIVFFLFFLFVVVVSLIFFKALLEVLTRARILKETSNFFQY
                     RKNWGSIIKGTLFRLSIIAFPQVSLLAIWEFTQVNSPAIVVDAVVILLIITGLLVYGT
                     IRVFIKGRESLRLYKNPAYLLYSDTYFLNKFGFLYVQFKADKFWWLLPLLSYAFLRSL
                     FVAVLQNQGKAQAMIIFVIELAYFVCLCWIRPYLDKRTNVFNIAIHLVNLINAFFFLF
                     FSNLFKQPAVVSSVMAVILFVLNAVFALFLLLFTIVTCTLALLHRNPDVRYQPMKDDR
                     VSFIPKIQNDFDGKNKNDSELFELRKAVMDTNENEEEKMFRDDTFGKNLNANTNTARL
                     FDDETSSSSFKQNSSPFDASEVTEQPVQPTSAVMGTGGSFLSPQYQRASSASRTNLAP
                     NNTSTSSLMKPESSLYLGNSNKSYSHFNNNGSNENARNNNPYL"
     gene            <48564..>51707
                     /gene="OAF1"
                     /locus_tag="YAL051W"
                     /gene_synonym="YAF1"
                     /db_xref="GeneID:851247"
     mRNA            <48564..>51707
                     /gene="OAF1"
                     /locus_tag="YAL051W"
                     /gene_synonym="YAF1"
                     /product="oleate-activated transcription factor OAF1"
                     /transcript_id="NM_001178195.2"
                     /db_xref="GeneID:851247"
     CDS             48564..51707
                     /gene="OAF1"
                     /locus_tag="YAL051W"
                     /gene_synonym="YAF1"
                     /note="Oleate-activated transcription factor; subunit of a
                     heterodimeric complex with Pip2p, which binds to
                     oleate-response elements (ORE) in the promoter of genes
                     involved in beta-oxidation of fatty acids, peroxisome
                     organization and biogenesis, activating transcription in
                     the presence of oleate; regulates chromatin silencing at
                     telomeres; involved in diauxic shift; OAF1 has a paralog,
                     PIP2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="oleate-activated transcription factor OAF1"
                     /protein_id="NP_009349.3"
                     /db_xref="GeneID:851247"
                     /db_xref="SGD:S000000048"
                     /translation="MVENSTQKAPHAGNDDNSSTKPYSEAFFLGFNNPTPGLEAEHSS
                     TSPAPENSETHNRKRNRILFVCQACRKSKTKCDREKPECGRCVKHGLKCVYDVSKQPA
                     PRIPSKDAIISRLEKDMFYWKDKAMKLLTEREVNESGKRSASPINTNNASGDSPDTKK
                     QHKMEPIYEQSGNGDINNGTRNDIEINLYRSHPTMIMSKVMKREVKPLSENYIIIQDC
                     FLKILVTSVFLDTSKNTMIPALTANANITRAQPSVANNLLKLKEMLIRQCQTEDEKNR
                     VNEFTDRILQNTNSNRNLKIGMLLSMLYNSVGYQYLEDHCPQGGEYSDLLRNLINECE
                     AILPSYEIIERYKNHFYEYVYPSLPFIELEIFEESLSQTIFPDPNNPSKVQIRMGSTH
                     LRAKVENLSLLLVILKLSYMSIRFLDHSTADSSFYLSKEIIDKYPIPNDFILLSQRCL
                     ASENWCACANENIISCLLYIWSFFAFSPEEGDFFLEHPTDVISSLIMMLSTSIGLHRD
                     PSDFPQLISPSTSDKRTLNHRRILWLSIVTVCSFEASLKGRHSVSPISLMALFLNIKD
                     PDSLTVYMNRVRGDLSDINNHKLLRIHKFTFKRAQLALLLSDLDNLTMTYYGSFHLHS
                     IEFIREKIEIFVEENFPIVPLKSVAQDKSDLDDMNVISEMNILSSENSSSFHNRIMNK
                     LLMLRTSMAVFLHFETLITKDKSIFPFYKKYFMVSCMDALSLINYFNKFFNGEYRHAI
                     SSLTSFNVTKFIQLALSSTIFSLLGIILRIGLAIHMLSSEVQKLSGTTDPRIKELNTK
                     VEKFSTLQRDLESALEGIYCSASEHLRFTYFPVFKMLALFDVIVQRMRKGELWHGIFT
                     MIQMEQMHSRIIKTLSITLGVKLDKKDRLLEELMACNHVANFSVEDIDELNRNIKKEI
                     QISSGLKPPVNTIDLTNGEPFGNAVPTFTKTWSSSLDNLEKLSSAAAVGQSLDYNSGL
                     RQGPLAGGGSKEQTPIAGMNNLNNSINATPIVDNSSGSQLPNGFDRGQANNTPFPGYF
                     GGLDLFDYDFLFGNDFA"
     gene            complement(<51855..>52595)
                     /gene="AIM2"
                     /locus_tag="YAL049C"
                     /db_xref="GeneID:851248"
     mRNA            complement(<51855..>52595)
                     /gene="AIM2"
                     /locus_tag="YAL049C"
                     /product="protein AIM2"
                     /transcript_id="NM_001178194.1"
                     /db_xref="GeneID:851248"
     CDS             complement(51855..52595)
                     /gene="AIM2"
                     /locus_tag="YAL049C"
                     /note="Cytoplasmic protein involved in mitochondrial
                     function or organization; null mutant displays reduced
                     frequency of mitochondrial genome loss; potential Hsp82p
                     interactor"
                     /codon_start=1
                     /product="protein AIM2"
                     /protein_id="NP_009350.1"
                     /db_xref="GeneID:851248"
                     /db_xref="SGD:S000000047"
                     /translation="MASNQPGKCCFEGVCHDGTPKGRREEIFGLDTYAAGSTSPKEKV
                     IVILTDVYGNKFNNVLLTADKFASAGYMVFVPDILFGDAISSDKPIDRDAWFQRHSPE
                     VTKKIVDGFMKLLKLEYDPKFIGVVGYCFGAKFAVQHISGDGGLANAAAIAHPSFVSI
                     EEIEAIDSKKPILISAAEEDHIFPANLRHLTEEKLKDNHATYQLDLFSGVAHGFAARG
                     DISIPAVKYAKEKVLLDQIYWFNHFSNV"
     gene            complement(<52801..>54789)
                     /gene="GEM1"
                     /locus_tag="YAL048C"
                     /gene_synonym="GON1"
                     /db_xref="GeneID:851249"
     mRNA            complement(<52801..>54789)
                     /gene="GEM1"
                     /locus_tag="YAL048C"
                     /gene_synonym="GON1"
                     /product="ERMES complex Ca(2+)-binding regulatory GTPase
                     GEM1"
                     /transcript_id="NM_001178193.1"
                     /db_xref="GeneID:851249"
     CDS             complement(52801..54789)
                     /gene="GEM1"
                     /locus_tag="YAL048C"
                     /gene_synonym="GON1"
                     /EC_number="3.6.5.-"
                     /note="Outer mitochondrial membrane GTPase, subunit of the
                     ERMES complex; potential regulatory subunit of the ERMES
                     complex that links the ER to mitochondria and may promote
                     inter-organellar calcium and phospholipid exchange as well
                     as coordinating mitochondrial DNA replication and growth;
                     cells lacking Gem1p contain collapsed, globular, or
                     grape-like mitochondria; ortholog of metazoan Miro
                     GTPases"
                     /codon_start=1
                     /product="ERMES complex Ca(2+)-binding regulatory GTPase
                     GEM1"
                     /protein_id="NP_009351.1"
                     /db_xref="GeneID:851249"
                     /db_xref="SGD:S000000046"
                     /translation="MTKETIRVVICGDEGVGKSSLIVSLTKAEFIPTIQDVLPPISIP
                     RDFSSSPTYSPKNTVLIDTSDSDLIALDHELKSADVIWLVYCDHESYDHVSLFWLPHF
                     RSLGLNIPVILCKNKCDSISNVNANAMVVSENSDDDIDTKVEDEEFIPILMEFKEIDT
                     CIKTSAKTQFDLNQAFYLCQRAITHPISPLFDAMVGELKPLAVMALKRIFLLSDLNQD
                     SYLDDNEILGLQKKCFNKSIDVNELNFIKDLLLDISKHDQEYINRKLYVPGKGITKDG
                     FLVLNKIYAERGRHETTWAILRTFHYTDSLCINDKILHPRLVVPDTSSVELSPKGYRF
                     LVDIFLKFDIDNDGGLNNQELHRLFKCTPGLPKLWTSTNFPFSTVVNNKGCITLQGWL
                     AQWSMTTFLNYSTTTAYLVYFGFQEDARLALQVTKPRKMRRRSGKLYRSNINDRKVFN
                     CFVIGKPCCGKSSLLEAFLGRSFSEEYSPTIKPRIAVNSLELKGGKQYYLILQELGEQ
                     EYAILENKDKLKECDVICLTYDSSDPESFSYLVSLLDKFTHLQDLPLVFVASKADLDK
                     QQQRCQIQPDELADELFVNHPLHISSRWLSSLNELFIKITEAALDPGKNTPGLPEETA
                     AKDVDYRQTALIFGSTVGFVALCSFTLMKLFKSSKFSK"
     gene            complement(<54989..>56857)
                     /gene="SPC72"
                     /locus_tag="YAL047C"
                     /gene_synonym="LDB4"
                     /db_xref="GeneID:851250"
     mRNA            complement(<54989..>56857)
                     /gene="SPC72"
                     /locus_tag="YAL047C"
                     /gene_synonym="LDB4"
                     /product="gamma-tubulin complex subunit SPC72"
                     /transcript_id="NM_001178192.2"
                     /db_xref="GeneID:851250"
     CDS             complement(54989..56857)
                     /gene="SPC72"
                     /locus_tag="YAL047C"
                     /gene_synonym="LDB4"
                     /note="Gamma-tubulin small complex (gamma-TuSC) receptor;
                     recruits the gamma-TuSC complex to the cytoplasmic side of
                     the SPB, connecting nuclear microtubules to the SPB;
                     involved in astral microtubule formation, stabilization,
                     and with Stu2p, anchoring astral MTs at the cytoplasmic
                     face of the SPB, and regulating plus-end MT dynamics;
                     regulated by Cdc5 kinase"
                     /codon_start=1
                     /product="gamma-tubulin complex subunit SPC72"
                     /protein_id="NP_009352.2"
                     /db_xref="GeneID:851250"
                     /db_xref="SGD:S000000045"
                     /translation="MVRRWIPSGRHLRNNDNTGDDDDSEFTNSMDSGMSIPSLRDSMT
                     TRSSHNDPIKPALMNDSNKVKNLEKELTNAKIKIQVLYEYIRRIPNKDGNAPSLGNDT
                     DFRNSIIEGLNLEINKLKQDLKAKEVEYQDTLQFVQENLENSESIVNTINHLLSFILT
                     HFNEQDENAHLLDKEERETLEETLELSSDYVLEKMDTLSKFIIQFLQDFLHSKSRAES
                     KQDKEEFLSLAQSSPAGSQLESRDSPSSKEENTDGGYQNDEIHDSNNHIDTENVMANS
                     TSLPISAVESRFEKTLDTQLEIVIENLHKEYDQFINSIRLKFEKSQKLEKIIASKLNE
                     QSHLLDSLELEENSSSVIEKQDHLISQLKEKIESQSVLINNLEKLKEDIIKMKQNEKV
                     LTKELETQTKINKLKENNWDSYINDLEKQINDLQIDKSEEFHVIQNQLDKLDLENYQL
                     KNQLNTLDNQKLILSQYESNFIKFNQNLLLHLDSIFNILQKILQESSIAQFDRKMKSI
                     KSVPNALKNLNLIQPKLESLYTFIETALESIINSYISSLISMETPEQPHQQGNELTAT
                     PNKELTLRIEELQRRWISERERRKLDANASEARIKALEQENESLRSKLFNLSINNP"
     gene            complement(<57029..>57385)
                     /gene="BOL3"
                     /locus_tag="YAL046C"
                     /gene_synonym="AIM1"
                     /db_xref="GeneID:851251"
     mRNA            complement(<57029..>57385)
                     /gene="BOL3"
                     /locus_tag="YAL046C"
                     /gene_synonym="AIM1"
                     /product="Bol3p"
                     /transcript_id="NM_001178191.1"
                     /db_xref="GeneID:851251"
     CDS             complement(57029..57385)
                     /gene="BOL3"
                     /locus_tag="YAL046C"
                     /gene_synonym="AIM1"
                     /note="Protein involved in Fe-S cluster transfer to
                     mitochondrial clients; protects [4Fe-4S] clusters from
                     damage due to oxidative stress by acting along with Nfu1p
                     at a late step in the transfer of [4Fe-4S] clusters from
                     the ISA complex to mitochondrial client proteins like
                     lipoate synthase and succinate dehydrogenase; sequence
                     similarity to human BOLA family member, BOLA3, mutations
                     of which are associated with Multiple Mitochondria
                     Dysfunctions Syndrome (MMDS2)"
                     /codon_start=1
                     /product="Bol3p"
                     /protein_id="NP_009353.1"
                     /db_xref="GeneID:851251"
                     /db_xref="SGD:S000000044"
                     /translation="MKLPQTMLRSISVKHVRWPRILTGSKLWYSTQMAMTPEEKMITD
                     KLQQELEPEVCKVQDVSGGCGSMFAINITSKKFNGLSLIKQHQLVNRILRDDISRWHG
                     LQLTTKKSTGKGPASS"
     gene            <57518..>57850
                     /gene="BOL1"
                     /locus_tag="YAL044W-A"
                     /db_xref="GeneID:851252"
     mRNA            <57518..>57850
                     /gene="BOL1"
                     /locus_tag="YAL044W-A"
                     /product="Bol1p"
                     /transcript_id="NM_001184453.1"
                     /db_xref="GeneID:851252"
     CDS             57518..57850
                     /gene="BOL1"
                     /locus_tag="YAL044W-A"
                     /note="Mitochondrial matrix protein involved in Fe-S
                     cluster biogenesis; facilitates [4Fe-2S] cluster inception
                     into mitochondrial proteins such as lipoate synthase and
                     succinate dehydrogenase; interacts and may function with
                     Grx5p at an early step in Fe-S cluster biosynthesis; forms
                     dimeric complexes with Grx5p and Nfu1p that alter the
                     stability of shared Fe/S clusters; sequence similarity to
                     human BOLA family member, BOLA1 and S. pombe uvi31, a
                     putative DNA repair protein"
                     /codon_start=1
                     /product="Bol1p"
                     /protein_id="NP_075206.1"
                     /db_xref="GeneID:851252"
                     /db_xref="SGD:S000007586"
                     /translation="MFKRAMSTDGPVARTILKRLECGFPDYKNFAFGLYNDSHKHKGH
                     AGVQGNVSAETHFRIEMVSKKFEGLKLPQRHRMVYSLLQDEMAQANGIHALQLSLKTP
                     QEYESKAK"
     gene            complement(<57950..>58462)
                     /gene="GCV3"
                     /locus_tag="YAL044C"
                     /db_xref="GeneID:851254"
     mRNA            complement(<57950..>58462)
                     /gene="GCV3"
                     /locus_tag="YAL044C"
                     /product="glycine decarboxylase subunit H"
                     /transcript_id="NM_001178189.1"
                     /db_xref="GeneID:851254"
     CDS             complement(57950..58462)
                     /gene="GCV3"
                     /locus_tag="YAL044C"
                     /note="H subunit of the mitochondrial glycine
                     decarboxylase complex; glycine decarboxylase is required
                     for the catabolism of glycine to 5,10-methylene-THF; also
                     required for all protein lipoylation; expression is
                     regulated by levels of 5,10-methylene-THF"
                     /codon_start=1
                     /product="glycine decarboxylase subunit H"
                     /protein_id="NP_009355.3"
                     /db_xref="GeneID:851254"
                     /db_xref="SGD:S000000042"
                     /translation="MLRTTRLWTTRMPTVSKLFLRNSSGNALNKNKLPFLYSSQGPQA
                     VRYTSQHEWIAVHQDKTAFVGITKYATDALGDATYVELPEVGTEIAQGESLGSIESVK
                     SASEIYQPADGTVEEINTNLEENPGVVNEDPMGDGWLVKMKLGEGVNVEQVEGLMSLE
                     QYEKTLVHDD"
     gene            complement(<58695..>61052)
                     /gene="PTA1"
                     /locus_tag="YAL043C"
                     /gene_synonym="FUN39"
                     /db_xref="GeneID:851255"
     mRNA            complement(<58695..>61052)
                     /gene="PTA1"
                     /locus_tag="YAL043C"
                     /gene_synonym="FUN39"
                     /product="RNA-processing protein PTA1"
                     /transcript_id="NM_001178188.1"
                     /db_xref="GeneID:851255"
     CDS             complement(58695..61052)
                     /gene="PTA1"
                     /locus_tag="YAL043C"
                     /gene_synonym="FUN39"
                     /note="Subunit of holo-CPF; holo-CPF is a multiprotein
                     complex and functional homolog of mammalian CPSF, required
                     for the cleavage and polyadenylation of mRNA and snoRNA 3'
                     ends; involved in pre-tRNA processing; binds to the
                     phosphorylated CTD of RNAPII"
                     /codon_start=1
                     /product="RNA-processing protein PTA1"
                     /protein_id="NP_009356.1"
                     /db_xref="GeneID:851255"
                     /db_xref="SGD:S000000041"
                     /translation="MSSAEMEQLLQAKTLAMHNNPTEMLPKVLETTASMYHNGNLSKL
                     KLPLAKFFTQLVLDVVSMDSPIANTERPFIAAQYLPLLLAMAQSTADVLVYKNIVLIM
                     CASYPLVLDLVAKTSNQEMFDQLCMLKKFVLSHWRTAYPLRATVDDETDVEQWLAQID
                     QNIGVKLATIKFISEVVLSQTKSPSGNEINSSTIPDNHPVLNKPALESEAKRLLDMLL
                     NYLIEEQYMVSSVFIGIINSLSFVIKRRPQTTIRILSGLLRFNVDAKFPLEGKSDLNY
                     KLSKRFVERAYKNFVQFGLKNQIITKSLSSGSGSSIYSKLTKISQTLHVIGEETKSKG
                     ILNFDPSKGNSKKTLSRQDKLKYISLWKRQLSALLSTLGVSTKTPTPVSAPATGSSTE
                     NMLDQLKILQKYTLNKASHQGNTFFNNSPKPISNTYSSVYSLMNSSNSNQDVTQLPND
                     ILIKLSTEAILQMDSTKLITGLSIVASRYTDLMNTYINSVPSSSSSKRKSDDDDDGND
                     NEEVGNDGPTANSKKIKMETEPLAEEPEEPEDDDRMQKMLQEEESAQEISGDANKSTS
                     AIKEIAPPFEPDSLTQDEKLKYLSKLTKKLFELSGRQDTTRAKSSSSSSILLDDDDSS
                     SWLHVLIRLVTRGIEAQEASDLIREELLGFFIQDFEQRVSLIIEWLNEEWFFQTSLHQ
                     DPSNYKKWSLRVLESLGPFLENKHRRFFIRLMSELPSLQSDHLEALKPICLDPARSSL
                     GFQTLKFLIMFRPPVQDTVRDLLHQLKQEDEGLHKQCDSLLDRLK"
     gene            <61316..>62563
                     /gene="ERV46"
                     /locus_tag="YAL042W"
                     /gene_synonym="FUN9"
                     /db_xref="GeneID:851256"
     mRNA            <61316..>62563
                     /gene="ERV46"
                     /locus_tag="YAL042W"
                     /gene_synonym="FUN9"
                     /product="Erv46p"
                     /transcript_id="NM_001178187.1"
                     /db_xref="GeneID:851256"
     CDS             61316..62563
                     /gene="ERV46"
                     /locus_tag="YAL042W"
                     /gene_synonym="FUN9"
                     /note="Protein localized to COPII-coated vesicles; forms a
                     complex with Erv41p; involved in the membrane fusion stage
                     of transport"
                     /codon_start=1
                     /product="Erv46p"
                     /protein_id="NP_009358.1"
                     /db_xref="GeneID:851256"
                     /db_xref="SGD:S000000040"
                     /translation="MKRSTLLSLDAFAKTEEDVRVRTRAGGLITLSCILTTLFLLVNE
                     WGQFNSVVTRPQLVVDRDRHAKLELNMDVTFPSMPCDLVNLDIMDDSGEMQLDILDAG
                     FTMSRLNSEGRPVGDATELHVGGNGDGTAPVNNDPNYCGPCYGAKDQSQNENLAQEEK
                     VCCQDCDAVRSAYLEAGWAFFDGKNIEQCEREGYVSKINEHLNEGCRIKGSAQINRIQ
                     GNLHFAPGKPYQNAYGHFHDTSLYDKTSNLNFNHIINHLSFGKPIQSHSKLLGNDKRH
                     GGAVVATSPLDGRQVFPDRNTHFHQFSYFAKIVPTRYEYLDNVVIETAQFSATFHSRP
                     LAGGRDKDHPNTLHVRGGIPGMFVFFEMSPLKVINKEQHGQTWSGFILNCITSIGGVL
                     AVGTVMDKLFYKAQRSIWGKKSQ"
     gene            <62840..>65404
                     /gene="CDC24"
                     /locus_tag="YAL041W"
                     /gene_synonym="CLS4"
                     /db_xref="GeneID:851190"
     mRNA            <62840..>65404
                     /gene="CDC24"
                     /locus_tag="YAL041W"
                     /gene_synonym="CLS4"
                     /product="Rho family guanine nucleotide exchange factor
                     CDC24"
                     /transcript_id="NM_001178186.1"
                     /db_xref="GeneID:851190"
     CDS             62840..65404
                     /gene="CDC24"
                     /locus_tag="YAL041W"
                     /gene_synonym="CLS4"
                     /note="Guanine nucleotide exchange factor (GEF) for
                     Cdc42p; required for polarity establishment and
                     maintenance, and mutants have morphological defects in bud
                     formation and shmooing; relocalizes from nucleus to
                     cytoplasm upon DNA replication stress; thermosensitivity
                     of the cdc24-4 mutant in the presence of sorbitol is
                     functionally complemented by human CDC42"
                     /codon_start=1
                     /product="Rho family guanine nucleotide exchange factor
                     CDC24"
                     /protein_id="NP_009359.1"
                     /db_xref="GeneID:851190"
                     /db_xref="SGD:S000000039"
                     /translation="MAIQTRFASGTSLSDLKPKPSATSISIPMQNVMNKPVTEQDSLF
                     HICANIRKRLEVLPQLKPFLQLAYQSSEVLSERQSLLLSQKQHQELLKSNGANRDSSD
                     LAPTLRSSSISTATSLMSMEGISYTNSNPSATPNMEDTLLTFSMGILPITMDCDPVTQ
                     LSQLFQQGAPLCILFNSVKPQFKLPVIASDDLKVCKKSIYDFILGCKKHFAFNDEELF
                     TISDVFANSTSQLVKVLEVVETLMNSSPTIFPSKSKTQQIMNAENQHRHQPQQSSKKH
                     NEYVKIIKEFVATERKYVHDLEILDKYRQQLLDSNLITSEELYMLFPNLGDAIDFQRR
                     FLISLEINALVEPSKQRIGALFMHSKHFFKLYEPWSIGQNAAIEFLSSTLHKMRVDES
                     QRFIINNKLELQSFLYKPVQRLCRYPLLVKELLAESSDDNNTKELEAALDISKNIARS
                     INENQRRTENHQVVKKLYGRVVNWKGYRISKFGELLYFDKVFISTTNSSSEPEREFEV
                     YLFEKIIILFSEVVTKKSASSLILKKKSSTSASISASNITDNNGSPHHSYHKRHSNSS
                     SSNNIHLSSSSAAAIIHSSTNSSDNNSNNSSSSSLFKLSANEPKLDLRGRIMIMNLNQ
                     IIPQNNRSLNITWESIKEQGNFLLKFKNEETRDNWSSCLQQLIHDLKNEQFKARHHSS
                     TSTTSSTAKSSSMMSPTTTMNTPNHHNSRQTHDSMASFSSSHMKRVSDVLPKRRTTSS
                     SFESEIKSISENFKNSIPESSILFRISYNNNSNNTSSSEIFTLLVEKVWNFDDLIMAI
                     NSKISNTHNNNISPITKIKYQDEDGDFVVLGSDEDWNVAKEMLAENNEKFLNIRLY"
     gene            complement(<65778..>67520)
                     /gene="CLN3"
                     /locus_tag="YAL040C"
                     /gene_synonym="DAF1; FUN10; WHI1"
                     /db_xref="GeneID:851191"
     mRNA            complement(<65778..>67520)
                     /gene="CLN3"
                     /locus_tag="YAL040C"
                     /gene_synonym="DAF1; FUN10; WHI1"
                     /product="cyclin CLN3"
                     /transcript_id="NM_001178185.1"
                     /db_xref="GeneID:851191"
     CDS             complement(65778..67520)
                     /gene="CLN3"
                     /locus_tag="YAL040C"
                     /gene_synonym="DAF1; FUN10; WHI1"
                     /note="G1 cyclin involved in cell cycle progression;
                     activates Cdc28p kinase to promote G1 to S phase
                     transition; plays a role in regulating transcription of
                     other G1 cyclins, CLN1 and CLN2; regulated by
                     phosphorylation and proteolysis; acetyl-CoA induces CLN3
                     transcription in response to nutrient repletion to promote
                     cell-cycle entry; cell cycle arrest phenotype of the cln1
                     cln2 cln3 triple null mutant is complemented by any of
                     human cyclins CCNA2, CCNB1, CCNC, CCND1, or CCNE1"
                     /codon_start=1
                     /product="cyclin CLN3"
                     /protein_id="NP_009360.1"
                     /db_xref="GeneID:851191"
                     /db_xref="SGD:S000000038"
                     /translation="MAILKDTIIRYANARYATASGTSTATAASVSAASCPNLPLLLQK
                     RRAIASAKSKNPNLVKRELQAHHSAISEYNNDQLDHYFRLSHTERPLYNLTNFNSQPQ
                     VNPKMRFLIFDFIMYCHTRLNLSTSTLFLTFTILDKYSSRFIIKSYNYQLLSLTALWI
                     SSKFWDSKNRMATLKVLQNLCCNQYSIKQFTTMEMHLFKSLDWSICQSATFDSYIDIF
                     LFQSTSPLSPGVVLSAPLEAFIQQKLALLNNAAGTAINKSSSSQGPSLNINEIKLGAI
                     MLCELASFNLELSFKYDRSLIALGAINLIKLSLNYYNSNLWENINLALEENCQDLDIK
                     LSEISNTLLDIAMDQNSFPSSFKSKYLNSNKTSLAKSLLDALQNYCIQLKLEEFYRSQ
                     ELETMYNTIFAQSFDSDSLTCVYSNATTPKSATVSSAATDYFSDHTHLRRLTKDSISP
                     PFAFTPTSSSSSPSPFNSPYKTSSSMTTPDSASHHSHSGSFSSTQNSFKRSLSIPQNS
                     SIFWPSPLTPTTPSLMSNRKLLQNLSVRSKRLFPVRPMATAHPCSAPTQLKKRSTSSV
                     DCDFNDSSNLKKTR"
     gene            complement(<68716..>69525)
                     /gene="CYC3"
                     /locus_tag="YAL039C"
                     /db_xref="GeneID:851192"
     mRNA            complement(<68716..>69525)
                     /gene="CYC3"
                     /locus_tag="YAL039C"
                     /product="holocytochrome c synthase CYC3"
                     /transcript_id="NM_001178184.1"
                     /db_xref="GeneID:851192"
     CDS             complement(68716..69525)
                     /gene="CYC3"
                     /locus_tag="YAL039C"
                     /EC_number="4.4.1.17"
                     /note="Cytochrome c heme lyase (holocytochrome c
                     synthase); attaches heme to apo-cytochrome c (Cyc1p or
                     Cyc7p) in mitochondrial intermembrane space; human homolog
                     HCCS implicated in microphthalmia with linear skin defects
                     (MLS), and can complement yeast null mutant"
                     /codon_start=1
                     /product="holocytochrome c synthase CYC3"
                     /protein_id="NP_009361.1"
                     /db_xref="GeneID:851192"
                     /db_xref="SGD:S000000037"
                     /translation="MGWFWADQKTTGKDIGGAAVSSMSGCPVMHESSSSSPPSSECPV
                     MQGDNDRINPLNNMPELAASKQPGQKMDLPVDRTISSIPKSPDSNEFWEYPSPQQMYN
                     AMVRKGKIGGSGEVAEDAVESMVQVHNFLNEGCWQEVLEWEKPHTDESHVQPKLLKFM
                     GKPGVLSPRARWMHLCGLLFPSHFSQELPFDRHDWIVLRGERKAEQQPPTFKEVRYVL
                     DFYGGPDDENGMPTFHVDVRPALDSLDNAKDRMTRFLDRMISGPSSSSSAP"
     rep_origin      70300..70469
                     /note="ARS106;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118318"
     gene            <71786..>73288
                     /gene="CDC19"
                     /locus_tag="YAL038W"
                     /gene_synonym="PYK1"
                     /db_xref="GeneID:851193"
     mRNA            <71786..>73288
                     /gene="CDC19"
                     /locus_tag="YAL038W"
                     /gene_synonym="PYK1"
                     /product="pyruvate kinase CDC19"
                     /transcript_id="NM_001178183.1"
                     /db_xref="GeneID:851193"
     CDS             71786..73288
                     /gene="CDC19"
                     /locus_tag="YAL038W"
                     /gene_synonym="PYK1"
                     /EC_number="2.7.1.40"
                     /note="Pyruvate kinase; functions as a homotetramer in
                     glycolysis to convert phosphoenolpyruvate to pyruvate, the
                     input for aerobic (TCA cycle) or anaerobic (glucose
                     fermentation) respiration; regulated via allosteric
                     activation by fructose bisphosphate; CDC19 has a paralog,
                     PYK2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="pyruvate kinase CDC19"
                     /protein_id="NP_009362.1"
                     /db_xref="GeneID:851193"
                     /db_xref="SGD:S000000036"
                     /translation="MSRLERLTSLNVVAGSDLRRTSIIGTIGPKTNNPETLVALRKAG
                     LNIVRMNFSHGSYEYHKSVIDNARKSEELYPGRPLAIALDTKGPEIRTGTTTNDVDYP
                     IPPNHEMIFTTDDKYAKACDDKIMYVDYKNITKVISAGRIIYVDDGVLSFQVLEVVDD
                     KTLKVKALNAGKICSHKGVNLPGTDVDLPALSEKDKEDLRFGVKNGVHMVFASFIRTA
                     NDVLTIREVLGEQGKDVKIIVKIENQQGVNNFDEILKVTDGVMVARGDLGIEIPAPEV
                     LAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPTRAEVSDVGNAILDGADCVMLSGE
                     TAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNCTPKPTSTTETVAASAVAAVFE
                     QKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAARFSHLYRGVFPFVFEKEPVS
                     DWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGHSNTLQVSTV"
     gene            complement(<73426..>73518)
                     /locus_tag="YAL037C-A"
                     /db_xref="GeneID:1466428"
     mRNA            complement(<73426..>73518)
                     /locus_tag="YAL037C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184629.1"
                     /db_xref="GeneID:1466428"
     CDS             complement(73426..73518)
                     /locus_tag="YAL037C-A"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878040.1"
                     /db_xref="GeneID:1466428"
                     /db_xref="SGD:S000028732"
                     /translation="MSISFPKMQHLIVMTTIGDKKVNNNIILFL"
     gene            <74020..>74823
                     /locus_tag="YAL037W"
                     /db_xref="GeneID:851194"
     mRNA            <74020..>74823
                     /locus_tag="YAL037W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001178182.1"
                     /db_xref="GeneID:851194"
     CDS             74020..74823
                     /locus_tag="YAL037W"
                     /note="hypothetical protein; YAL037W has a paralog,
                     YOR342C, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009363.1"
                     /db_xref="GeneID:851194"
                     /db_xref="SGD:S000000035"
                     /translation="MDMEIEDSSPIDDLKLQKLDTNVYFGPCEILTQPILLQYENIKF
                     IIGVNLSTEKIASFYTQYFRNSNSVVVNLCSPTTAAVATKKAAIDLYIRNNTILLQKF
                     VGQYLQMGKKIKTSLTQAQTDTIQSLPQFCNSNVLSGEPLVQYQAFNDLLALFKSFSH
                     FGNILVISSHSYDCALLKFLISRVMTYYPLVTIQDSLQYMKATLNISISTSDEFDILN
                     DKELWEFGQTQEILKRRQTSSVKRRCVNLPENSTIDNRMLMGTTKRGRF"
     gene            complement(<75043..>76152)
                     /gene="RBG1"
                     /locus_tag="YAL036C"
                     /gene_synonym="FUN11"
                     /db_xref="GeneID:851195"
     mRNA            complement(<75043..>76152)
                     /gene="RBG1"
                     /locus_tag="YAL036C"
                     /gene_synonym="FUN11"
                     /product="GTP-binding protein RBG1"
                     /transcript_id="NM_001178181.1"
                     /db_xref="GeneID:851195"
     CDS             complement(75043..76152)
                     /gene="RBG1"
                     /locus_tag="YAL036C"
                     /gene_synonym="FUN11"
                     /note="Member of the DRG family of GTP-binding proteins;
                     associates with translating ribosomes; interacts with
                     Tma46p, Ygr250cp, Gir2p and Yap1p via two-hybrid"
                     /codon_start=1
                     /product="GTP-binding protein RBG1"
                     /protein_id="NP_009364.1"
                     /db_xref="GeneID:851195"
                     /db_xref="SGD:S000000034"
                     /translation="MSTTVEKIKAIEDEMARTQKNKATSFHLGQLKAKLAKLRRELLT
                     SASSGSGGGAGIGFDVARTGVASVGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVT
                     VPGVIRYKGAKIQMLDLPGIIDGAKDGRGRGKQVIAVARTCNLLFIILDVNKPLHHKQ
                     IIEKELEGVGIRLNKTPPDILIKKKEKGGISITNTVPLTHLGNDEIRAVMSEYRINSA
                     EIAFRCDATVDDLIDVLEASSRRYMPAIYVLNKIDSLSIEELELLYRIPNAVPISSGQ
                     DWNLDELLQVMWDRLNLVRIYTKPKGQIPDFTDPVVLRSDRCSVKDFCNQIHKSLVDD
                     FRNALVYGSSVKHQPQYVGLSHILEDEDVVTILKK"
     gene            <76427..>79435
                     /gene="FUN12"
                     /locus_tag="YAL035W"
                     /gene_synonym="yIF2"
                     /db_xref="GeneID:851196"
     mRNA            <76427..>79435
                     /gene="FUN12"
                     /locus_tag="YAL035W"
                     /gene_synonym="yIF2"
                     /product="translation initiation factor eIF5B"
                     /transcript_id="NM_001178180.1"
                     /db_xref="GeneID:851196"
     CDS             76427..79435
                     /gene="FUN12"
                     /locus_tag="YAL035W"
                     /gene_synonym="yIF2"
                     /EC_number="3.6.5.3"
                     /note="Translation initiation factor eIF5B; GTPase that
                     promotes Met-tRNAiMet binding to ribosomes and ribosomal
                     subunit joining; promotes GTP-dependent maturation of 18S
                     rRNA by Nob1p; protein abundance increases in response to
                     DNA replication stress; homolog of bacterial IF2"
                     /codon_start=1
                     /product="translation initiation factor eIF5B"
                     /protein_id="NP_009365.1"
                     /db_xref="GeneID:851196"
                     /db_xref="SGD:S000000033"
                     /translation="MAKKSKKNQQNYWDEEFEEDAAQNEEISATPTPNPESSAGADDT
                     SREASASAEGAEAIEGDFMSTLKQSKKKQEKKVIEEKKDGKPILKSKKEKEKEKKEKE
                     KQKKKEQAARKKAQQQAQKEKNKELNKQNVEKAAAEKAAAEKSQKSKGESDKPSASAK
                     KPAKKVPAGLAALRRQLELKKQLEEQEKLEREEEERLEKEEEERLANEEKMKEEAKAA
                     KKEKEKAKREKRKAEGKLLTRKQKEEKKLLERRRAALLSSGNVKVAGLAKKDGEENKP
                     KKVVYSKKKKRTTQENASEAIKSDSKKDSEVVPDDELKESEDVLIDDWENLALGDDDE
                     EGTNEETQESTASHENEDQNQGEEEEEGEEEEEEEEERAHVHEVAKSTPAATPAATPT
                     PSSASPNKKDLRSPICCILGHVDTGKTKLLDKIRQTNVQGGEAGGITQQIGATYFPID
                     AIKAKTKVMAEYEKQTFDVPGLLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGLE
                     QQTIESIKLLRDRKAPFVVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRYS
                     KIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKRMSKQL
                     MYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLTPQ
                     PLRELRLKSEYVHHKEVKAALGVKIAANDLEKAVSGSRLLVVGPEDDEDELMDDVMDD
                     LTGLLDSVDTTGKGVVVQASTLGSLEALLDFLKDMKIPVMSIGLGPVYKRDVMKASTM
                     LEKAPEYAVMLCFDVKVDKEAEQYAEQEGIKIFNADVIYHLFDSFTAYQEKLLEERRK
                     DFLDYAIFPCVLQTLQIINKRGPMIIGVDVLEGTLRVGTPICAVKTDPTTKERQTLIL
                     GKVISLEINHQPVQEVKKGQTAAGVAVRLEDPSGQQPIWGRHVDENDTLYSLVSRRSI
                     DTLKDKAFRDQVARSDWLLLKKLKVVFGIE"
     gene            <79718..>80587
                     /gene="MTW1"
                     /locus_tag="YAL034W-A"
                     /gene_synonym="DSN3; NSL2"
                     /db_xref="GeneID:851197"
     mRNA            <79718..>80587
                     /gene="MTW1"
                     /locus_tag="YAL034W-A"
                     /gene_synonym="DSN3; NSL2"
                     /product="MIND complex subunit MTW1"
                     /transcript_id="NM_001178179.1"
                     /db_xref="GeneID:851197"
     CDS             79718..80587
                     /gene="MTW1"
                     /locus_tag="YAL034W-A"
                     /gene_synonym="DSN3; NSL2"
                     /note="Essential component of the MIND kinetochore
                     complex; joins kinetochore subunits contacting DNA to
                     those contacting microtubules; critical to kinetochore
                     assembly; complex consists of Mtw1p Including
                     Nnf1p-Nsl1p-Dsn1p (MIND)"
                     /codon_start=1
                     /product="MIND complex subunit MTW1"
                     /protein_id="NP_009367.1"
                     /db_xref="GeneID:851197"
                     /db_xref="SGD:S000000032"
                     /translation="MSAPTMRSTSILTEHLGYPPISLVDDIINAVNEIMYKCTAAMEK
                     YLLSKSKIGEEDYGEEIKSGVAKLESLLENSVDKNFDKLELYVLRNVLRIPEEYLDAN
                     VFRLENQKDLVIVDENELKKSEEKLREKVNDVELAFKKNEMLLKRVTKVKRLLFTIRG
                     FKQKLNELLKCKDDVQLQKILESLKPIDDTMTLLTDSLRKLYVDSESTSSTEEVEALL
                     QRLKTNGKQNNKDFRTRYIDIRTNNVLRKLGLLGDKEDEKQSAKPDARTQAGDIVSID
                     IEEPQLDLLDDVL"
     gene            complement(<80710..>81951)
                     /gene="FUN19"
                     /locus_tag="YAL034C"
                     /db_xref="GeneID:851199"
     mRNA            complement(<80710..>81951)
                     /gene="FUN19"
                     /locus_tag="YAL034C"
                     /product="Fun19p"
                     /transcript_id="NM_001180035.1"
                     /db_xref="GeneID:851199"
     CDS             complement(80710..81951)
                     /gene="FUN19"
                     /locus_tag="YAL034C"
                     /note="Non-essential hypothetical protein; expression
                     induced in response to heat stress; FUN19 has a paralog,
                     YOR338W, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="Fun19p"
                     /protein_id="NP_009368.2"
                     /db_xref="GeneID:851199"
                     /db_xref="SGD:S000002134"
                     /translation="MGLYSPESEKSQLNMNYIGKDDSQSIFRRLNQNLKASNNNNDSN
                     KNGLNMSDYSNNSPYGRSYDVRINQNSQNNGNGCFSGSIDSLVDEHIIPSPPLSPKLE
                     SKISHNGSPRMASSVLVGSTPKGAVENVLFVKPVWPNGLSRKRYRYATYGFLSQYKIF
                     SNLAQPYSKNIINRYNNLAYNARHKYSKYNDDMTPPPLPSSSSRLPSPLASPNLNRQA
                     RYNMRKQALYNNNLGKFESDTEWIPRKRKVYSPQRRTMTTSPHRAKKFSPSASTPHTN
                     IASIEAIHDAPQYIPNVSWKKLPDYSPPLSTLPTDSNKSLKIEWKGSPMDLSTDPLRN
                     ELHPAELVLAQTLRLPCDLYLDSKRRLFLEKVYRLKKGLPFRRTDAQKACRIDVNKAS
                     RLFQAFEKVGWLQDSNFTKYL"
     gene            <82706..>83227
                     /gene="POP5"
                     /locus_tag="YAL033W"
                     /gene_synonym="FUN53"
                     /db_xref="GeneID:851200"
     mRNA            <82706..>83227
                     /gene="POP5"
                     /locus_tag="YAL033W"
                     /gene_synonym="FUN53"
                     /product="RNA-binding protein POP5"
                     /transcript_id="NM_001178178.1"
                     /db_xref="GeneID:851200"
     CDS             82706..83227
                     /gene="POP5"
                     /locus_tag="YAL033W"
                     /gene_synonym="FUN53"
                     /EC_number="3.1.26.5"
                     /note="Subunit of both RNase MRP and nuclear RNase P;
                     RNase MRP cleaves pre-rRNA, while nuclear RNase P cleaves
                     tRNA precursors to generate mature 5' ends and facilitates
                     turnover of nuclear RNAs"
                     /codon_start=1
                     /product="RNA-binding protein POP5"
                     /protein_id="NP_009369.1"
                     /db_xref="GeneID:851200"
                     /db_xref="SGD:S000000031"
                     /translation="MVRLKSRYILFEIIFPPTDTNVEESVSKADILLSHHRASPADVS
                     IKSILQEIRRSLSLNLGDYGSAKCNSLLQLKYFSNKTSTGIIRCHREDCDLVIMALML
                     MSKIGDVDGLIVNPVKVSGTIKKIEQFAMRRNSKILNIIKCSQSSHLSDNDFIINDFK
                     KIGRENENENEDD"
     gene            complement(<83335..>84474)
                     /gene="PRP45"
                     /locus_tag="YAL032C"
                     /gene_synonym="FUN20"
                     /db_xref="GeneID:851201"
     mRNA            complement(<83335..>84474)
                     /gene="PRP45"
                     /locus_tag="YAL032C"
                     /gene_synonym="FUN20"
                     /product="mRNA splicing protein PRP45"
                     /transcript_id="NM_001178177.1"
                     /db_xref="GeneID:851201"
     CDS             complement(83335..84474)
                     /gene="PRP45"
                     /locus_tag="YAL032C"
                     /gene_synonym="FUN20"
                     /note="Protein required for pre-mRNA splicing; associates
                     with the spliceosome and interacts with splicing factors
                     Prp22p and Prp46p; orthologous to human transcriptional
                     coactivator SKIP and can activate transcription of a
                     reporter gene"
                     /codon_start=1
                     /product="mRNA splicing protein PRP45"
                     /protein_id="NP_009370.1"
                     /db_xref="GeneID:851201"
                     /db_xref="SGD:S000000030"
                     /translation="MFSNRLPPPKHSQGRVSTALSSDRVEPAILTDQIAKNVKLDDFI
                     PKRQSNFELSVPLPTKAEIQECTARTKSYIQRLVNAKLANSNNRASSRYVTETHQAPA
                     NLLLNNSHHIEVVSKQMDPLLPRFVGKKARKVVAPTENDEVVPVLHMDGSNDRGEADP
                     NEWKIPAAVSNWKNPNGYTVALERRVGKALDNENNTINDGFMKLSEALENADKKARQE
                     IRSKMELKRLAMEQEMLAKESKLKELSQRARYHNGTPQTGAIVKPKKQTSTVARLKEL
                     AYSQGRDVSEKIILGAAKRSEQPDLQYDSRFFTRGANASAKRHEDQVYDNPLFVQQDI
                     ESIYKTNYEKLDEAVNVKSEGASGSHGPIQFTKAESDDKSDNYGA"
     gene            complement(<84749..>87031)
                     /gene="GIP4"
                     /locus_tag="YAL031C"
                     /gene_synonym="FUN21"
                     /db_xref="GeneID:851202"
     mRNA            complement(<84749..>87031)
                     /gene="GIP4"
                     /locus_tag="YAL031C"
                     /gene_synonym="FUN21"
                     /product="protein phosphatase regulator GIP4"
                     /transcript_id="NM_001178176.1"
                     /db_xref="GeneID:851202"
     CDS             complement(84749..87031)
                     /gene="GIP4"
                     /locus_tag="YAL031C"
                     /gene_synonym="FUN21"
                     /note="Cytoplasmic protein that regulates protein
                     phosphatase 1 Glc7p; protein overexpression relocalizes
                     Glc7p from the nucleus and prevents chromosome
                     segregation; potential Cdc28p substrate"
                     /codon_start=1
                     /product="protein phosphatase regulator GIP4"
                     /protein_id="NP_009371.1"
                     /db_xref="GeneID:851202"
                     /db_xref="SGD:S000000029"
                     /translation="MVDVQKRKKLLAKAAASASIPAIKGSVPLDSYDIKIIQYKNALY
                     KLNELNRLLNVLVPHLKKKRDNDESYKIIPLVNFILSLCEGPIFNVSPVLAKRYHLLC
                     RFQLIKLSEVQQRLSTNFIDVEGWMFPEEVPLDHYKSCIYNNSLQWKILNSLSCIAQN
                     AIKIYNAKLRQILLERDAYKARSLPFDTSIIEDLLNPVEMTLILDLAVLINDPVRDKS
                     THSFYKLQWQVMEKLNSCVHSKIFPILRTYYNQLQKFSETRPTSLSNLQKDLPHWEWT
                     LHRIYTFHLRVFSVLCVIISFSRQIFLPNKQHFLDIKTRLSSENVYHYDLIICELMAL
                     LSPECDDVTALFELQENLKFWTQTARTDNNSSRTPIFHLQPGLVVELFNNHICKIIPK
                     LRSIMGLLSNWMDCWKYIEKNYKTFDETNDLRENLKEKLERDKALYLEVKNAKSKLKK
                     KPSITKLPASSSPSPSPTSSASPSRQASLESIRTRARAHLASNSSRSPSVSPVRTTFN
                     NKNAETKKSVVSPEKRKLINGRRPRSSSLQSYTNKQQTSYLNSTRHPSIAPPSKLNNQ
                     RSNSLQSSTMTLNQKIVQDTVRHLMNKSASTPNPSASSSLAPSPKVSSINNTSSGKSS
                     STLIANSSDTLAIETLTLDPESNSSELSIKRVRFAGVPPMTEAENPKPTKVGWYKKPA
                     VLHYPPIPASAMIKPLQHKSKYNTLRQEEGFTFRKSLRDGLEWENGESGSETTMMPFG
                     IEIKESTGHRIASKIRSKLR"
     gene            <87286..>87752
                     /gene="SNC1"
                     /locus_tag="YAL030W"
                     /db_xref="GeneID:851203"
     mRNA            join(<87286..87387,87501..>87752)
                     /gene="SNC1"
                     /locus_tag="YAL030W"
                     /product="SNAP receptor SNC1"
                     /transcript_id="NM_001178175.1"
                     /db_xref="GeneID:851203"
     CDS             join(87286..87387,87501..87752)
                     /gene="SNC1"
                     /locus_tag="YAL030W"
                     /note="Vesicle membrane receptor protein (v-SNARE);
                     involved in the fusion between Golgi-derived secretory
                     vesicles with the plasma membrane; proposed to be involved
                     in endocytosis; member of the synaptobrevin/VAMP family of
                     R-type v-SNARE proteins; SNC1 has a paralog, SNC2, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="SNAP receptor SNC1"
                     /protein_id="NP_009372.1"
                     /db_xref="GeneID:851203"
                     /db_xref="SGD:S000000028"
                     /translation="MSSSTPFDPYALSEHDEERPQNVQSKSRTAELQAEIDDTVGIMR
                     DNINKVAERGERLTSIEDKADNLAVSAQGFKRGANRVRKAMWYKDLKMKMCLALVIII
                     LLVVIIVPIAVHFSR"
     gene            complement(<87855..>92270)
                     /gene="MYO4"
                     /locus_tag="YAL029C"
                     /gene_synonym="FUN22; SHE1"
                     /db_xref="GeneID:851204"
     mRNA            complement(<87855..>92270)
                     /gene="MYO4"
                     /locus_tag="YAL029C"
                     /gene_synonym="FUN22; SHE1"
                     /product="myosin 4"
                     /transcript_id="NM_001178174.1"
                     /db_xref="GeneID:851204"
     CDS             complement(87855..92270)
                     /gene="MYO4"
                     /locus_tag="YAL029C"
                     /gene_synonym="FUN22; SHE1"
                     /note="Type V myosin motor involved in actin-based
                     transport of cargos; required for mRNA transport,
                     including ASH1 mRNA, and facilitating the growth and
                     movement of ER tubules into the growing bud along with
                     She3p; MYO4 has a paralog, MYO2, that arose from the whole
                     genome duplication"
                     /codon_start=1
                     /product="myosin 4"
                     /protein_id="NP_009373.1"
                     /db_xref="GeneID:851204"
                     /db_xref="SGD:S000000027"
                     /translation="MSFEVGTKCWYPHKEQGWIGGEVTKNDFFEGTFHLELKLEDGET
                     VSIETNSFENDDDHPTLPVLRNPPILESTDDLTTLSYLNEPAVLHAIKKRYMNGQIYT
                     YSGIVLIAANPFDKVDHLYSREMIQNYSSKRKDELEPHLFAIAEEAYRFMVHEKANQT
                     VVVSGESGAGKTVSAKYIMRYFASVQESNNREGEVEMSQIESQILATNPIMEAFGNAK
                     TTRNDNSSRFGKYLQILFDENTTIRGSKIRTYLLEKSRLVYQPETERNYHIFYQILEG
                     LPEPVKQELHLSSPKDYHYTNQGGQPNIAGIDEAREYKITTDALSLVGINHETQLGIF
                     KILAGLLHIGNIEMKMTRNDASLSSEEQNLQIACELLGIDPFNFAKWIVKKQIVTRSE
                     KIVTNLNYNQALIARDSVAKFIYSTLFDWLVDNINKTLYDPELDQQDHVFSFIGILDI
                     YGFEHFEKNSFEQFCINYANEKLQQEFNQHVFKLEQEEYVKEEIEWSFIEFSDNQPCI
                     DLIENKLGILSLLDEESRLPSGSDESWASKLYSAFNKPPSNEVFSKPRFGQTKFIVSH
                     YAVDVEYEVEGFIEKNRDSVSLGHLDVFKATTNPIFKQILDNRELRSDDAPEEQNTEK
                     KIMIPARLSQKKPTLGSMFKKSLGELMAIINSTNVHYIRCIKPNSEKKPWEFDNLMVL
                     SQLRACGVLETIRISCAGFPSRWTFDEFVQRYFLLTDYSLWSGILYNPDLPKEAIVNF
                     CQSILDATISDSAKYQIGNTKIFFKAGMLAFLEKLRTNKMNEICIIIQKKIRARYYRL
                     QYLQTMESIKKCQSQIRSLLVRTRVDHELKTRAAILLQTNIRALWKREYYRAAIGQII
                     KLQCTCKRKLILDSVNRKFMLMAAVIIQSYIRSYGHKTDYRTLKRSSILVQSAMRMQL
                     ARRRYIVLQKEVEERNIRASYGIGLLEEAIEFKNSFILNLEMLNDSYTRLTQLLQGDL
                     SNIPSKQRQEYETIVNGYNDKISKLKTLQVEIMNTLNKKNALKERKKKQSSLIQSHMQ
                     SLAAIKGNKPSRLSDEVKSMKQELAFIENVIAQDFTTTYSANKNDKVKGLGIAGQQVK
                     PKLVNVIRRESGNPDLLELLMDLNCYTLEVTEGYLKKVNVTEVNGDNVLGPIHVITTV
                     VSSLVRNGLLIQSSKFISKVLLTVESIVMSLPKDETMLGGIFWLSNLSRLPAFAANQK
                     TLYEANGGDEKDKLTLIYLNDLENETLKVFDKIYSTWLVKFMKHASAHIEIFDMVLNE
                     KLFKNSGDEKFAKLFTFLNEFDAVLCKFQVVDSMHTKIFNDTLKYLNVMLFNDLITKC
                     PALNWKYGYEVDRNIERLVSWFEPRIEDVRPNLIQIIQAVKILQLKISNLNEFKLLFD
                     FWYALNPAQIQAILLKYKPANKGEAGVPNEILNYLANVIKRENLSLPGKMEIMLSAQF
                     DSAKNHLRYDTSAITQNSNTEGLATVSKIIKLDRK"
     gene            <92900..>94486
                     /gene="FRT2"
                     /locus_tag="YAL028W"
                     /gene_synonym="HPH2"
                     /db_xref="GeneID:851205"
     mRNA            <92900..>94486
                     /gene="FRT2"
                     /locus_tag="YAL028W"
                     /gene_synonym="HPH2"
                     /product="Frt2p"
                     /transcript_id="NM_001178173.1"
                     /db_xref="GeneID:851205"
     CDS             92900..94486
                     /gene="FRT2"
                     /locus_tag="YAL028W"
                     /gene_synonym="HPH2"
                     /note="Tail-anchored ER membrane hypothetical protein;
                     interacts with homolog Frt1p; promotes growth in
                     conditions of high Na+, alkaline pH, or cell wall stress,
                     possibly via a role in posttranslational translocation;
                     potential Cdc28p substrate; FRT2 has a paralog, FRT1, that
                     arose from the whole genome duplication"
                     /codon_start=1
                     /product="Frt2p"
                     /protein_id="NP_009374.1"
                     /db_xref="GeneID:851205"
                     /db_xref="SGD:S000000026"
                     /translation="MQNAQIKSSSKGSGIDGTDRNSKDGVEKRPLEDVKQMIDAGTPD
                     VGHKSTVETKPNVGWQASHSNLAALHEKEQKYEMEHHHARHKLHRQVIPDYTSASTAM
                     FSDCMFNAAPDKVRSLSTMKSSGLSPKHPFNVVATFKGPFPQHSVESKPLDGGYSAKD
                     HFPSFKMLQAQQHPAHRHYKDNDKYGLKSPSRSFVKDKKRLVHRFLKSMEPSSSGQSK
                     DSSALAPAFDPILPNVISKPSKRPTHHSHSSDGSSSTQTDISLQSLLYHDLESSPKKH
                     VSPSRPPSVASESSPAVANPIGLSPKDACNASFSQSSSSSLSSSSSSSSSTSFSQSVA
                     VDPLEPPGNITYSSSNLSLNSDELDYYQRHIGLQLQQTEALLKHSLKDEVLKDENDLV
                     KNIANFDKIVKELRDLRSRTIGWKELVEEDYLMNLKQDFDKENPESFEARLSDTINTN
                     VAKLQDLEKRMASCKDRLASRKEVMRKMESLLSLENSLMISKKNVTFASKYRNEALDI
                     VFLIIIIVICYTFKHLVSHK"
     gene            <94687..>95472
                     /gene="SAW1"
                     /locus_tag="YAL027W"
                     /db_xref="GeneID:851206"
     mRNA            <94687..>95472
                     /gene="SAW1"
                     /locus_tag="YAL027W"
                     /product="DNA-binding protein SAW1"
                     /transcript_id="NM_001178172.1"
                     /db_xref="GeneID:851206"
     CDS             94687..95472
                     /gene="SAW1"
                     /locus_tag="YAL027W"
                     /note="5'- and 3'-flap DNA binding protein; recruits
                     Rad1p-Rad10p to single-strand annealing intermediates with
                     3' non-homologous tails for removal during double-strand
                     break repair; complexes with Rad1p-Rad10p and stimulates
                     its endonuclease activity; green fluorescent protein
                     (GFP)-fusion protein localizes to the nucleus"
                     /codon_start=1
                     /product="DNA-binding protein SAW1"
                     /protein_id="NP_009375.1"
                     /db_xref="GeneID:851206"
                     /db_xref="SGD:S000000025"
                     /translation="MAPSIATVKIARDMVLPLRIFVNRKQILQTNDKTSNKSNATIFE
                     APLLSNNSIICLKSPNTRIYLSQQDKKNLCDEIKEDLLLIVYELASPEIISSVLSKIR
                     VGHSTDFQINVLPKLFAGADTDNAVTSHIQSVTRLAKFKYKLHYKHKWELDIFINSIK
                     KIANLRHYLMFQTLTLNGFSLNAGPKTLLARKIEKQPQVPNLLIENGDADALDTPVEE
                     DIKPVIEFMYKPVINLGEIIDVHVLHRPRRHKVRTQSKQPQEE"
     gene            complement(<95630..>99697)
                     /gene="DRS2"
                     /locus_tag="YAL026C"
                     /gene_synonym="FUN38; SWA3"
                     /db_xref="GeneID:851207"
     mRNA            complement(<95630..>99697)
                     /gene="DRS2"
                     /locus_tag="YAL026C"
                     /gene_synonym="FUN38; SWA3"
                     /product="aminophospholipid-translocating P4-type ATPase
                     DRS2"
                     /transcript_id="NM_001178171.2"
                     /db_xref="GeneID:851207"
     CDS             complement(95630..99697)
                     /gene="DRS2"
                     /locus_tag="YAL026C"
                     /gene_synonym="FUN38; SWA3"
                     /EC_number="3.6.3.1"
                     /note="Trans-golgi network aminophospholipid translocase
                     (flippase); maintains membrane lipid asymmetry in
                     post-Golgi secretory vesicles; contributes to
                     clathrin-coated vesicle formation, endocytosis, protein
                     trafficking between the Golgi and endosomal system and the
                     cellular response to mating pheromone; autoinhibited by
                     its C-terminal tail; localizes to the trans-Golgi network;
                     mutations in human homolog ATP8B1 result in liver disease"
                     /codon_start=1
                     /product="aminophospholipid-translocating P4-type ATPase
                     DRS2"
                     /protein_id="NP_009376.2"
                     /db_xref="GeneID:851207"
                     /db_xref="SGD:S000000024"
                     /translation="MNDDRETPPKRKPGEDDTLFDIDFLDDTTSHSGSRSKVTNSHAN
                     ANYIPPSHVLPEETIDLDADDDNIENDVHENLFMSNNHDDQTSWNANRFDSDAYQPQS
                     LRAVKPPGLFARFGNGLKNAFTFKRKKGPESFEMNHYNAVTNNELDDNYLDSRNKFNI
                     KILFNRYILRKNVGDAEGNGEPRVIHINDSLANSSFGYSDNHISTTKYNFATFLPKFL
                     FQEFSKYANLFFLCTSAIQQVPHVSPTNRYTTIGTLLVVLIVSAMKECIEDIKRANSD
                     KELNNSTAEIFSEAHDDFVEKRWIDIRVGDIIRVKSEEPIPADTIILSSSEPEGLCYI
                     ETANLDGETNLKIKQSRVETAKFIDVKTLKNMNGKVVSEQPNSSLYTYEGTMTLNDRQ
                     IPLSPDQMILRGATLRNTAWIFGLVIFTGHETKLLRNATATPIKRTAVEKIINRQIIA
                     LFTVLIVLILISSIGNVIMSTADAKHLSYLYLEGTNKAGLFFKDFLTFWILFSNLVPI
                     SLFVTVELIKYYQAFMIGSDLDLYYEKTDTPTVVRTSSLVEELGQIEYIFSDKTGTLT
                     RNIMEFKSCSIAGHCYIDKIPEDKTATVEDGIEVGYRKFDDLKKKLNDPSDEDSPIIN
                     DFLTLLATCHTVIPEFQSDGSIKYQAASPDEGALVQGGADLGYKFIIRKPNSVTVLLE
                     ETGEEKEYQLLNICEFNSTRKRMSAIFRFPDGSIKLFCKGADTVILERLDDEANQYVE
                     ATMRHLEDYASEGLRTLCLAMRDISEGEYEEWNSIYNEAATTLDNRAEKLDEAANLIE
                     KNLILIGATAIEDKLQDGVPETIHTLQEAGIKIWVLTGDRQETAINIGMSCRLLSEDM
                     NLLIINEETRDDTERNLLEKINALNEHQLSTHDMNTLALVIDGKSLGFALEPELEDYL
                     LTVAKLCKAVICCRVSPLQKALVVKMVKRKSSSLLLAIGDGANDVSMIQAAHVGVGIS
                     GMEGMQAARSADIAVGQFKFLKKLLLVHGSWSYQRISVAILYSFYKNTALYMTQFWYV
                     FANAFSGQSIMESWTMSFYNLFFTVWPPFVIGVFDQFVSSRLLERYPQLYKLGQKGQF
                     FSVYIFWGWIINGFFHSAIVFIGTILIYRYGFALNMHGELADHWSWGVTVYTTSVIIV
                     LGKAALVTNQWTKFTLIAIPGSLLFWLIFFPIYASIFPHANISREYYGVVKHTYGSGV
                     FWLTLIVLPIFALVRDFLWKYYKRMYEPETYHVIQEMQKYNISDSRPHVQQFQNAIRK
                     VRQVQRMKKQRGFAFSQAEEGGQEKIVRMYDTTQKRGKYGELQDASANPFNDNNGLGS
                     NDFESAEPFIENPFADGNQNSNRFSSSRDDISFDI"
     gene            99305..99868
                     /locus_tag="HRA1"
                     /db_xref="GeneID:9164866"
     ncRNA           99305..99868
                     /ncRNA_class="other"
                     /locus_tag="HRA1"
                     /product="HRA1"
                     /note="ncRNA; Non-protein-coding RNA; substrate of RNase
                     P, possibly involved in rRNA processing, specifically
                     maturation of 20S precursor into the mature 18S rRNA"
                     /transcript_id="NR_132149.1"
                     /db_xref="GeneID:9164866"
                     /db_xref="SGD:S000119380"
     gene            complement(<100225..>101145)
                     /gene="MAK16"
                     /locus_tag="YAL025C"
                     /db_xref="GeneID:851208"
     mRNA            complement(<100225..>101145)
                     /gene="MAK16"
                     /locus_tag="YAL025C"
                     /product="ribosome biosynthesis protein MAK16"
                     /transcript_id="NM_001178170.2"
                     /db_xref="GeneID:851208"
     CDS             complement(100225..101145)
                     /gene="MAK16"
                     /locus_tag="YAL025C"
                     /note="Essential nuclear protein; constituent of 66S
                     pre-ribosomal particles; required for maturation of 25S
                     and 5.8S rRNAs; required for maintenance of M1 satellite
                     double-stranded RNA of the L-A virus"
                     /codon_start=1
                     /product="ribosome biosynthesis protein MAK16"
                     /protein_id="NP_009377.2"
                     /db_xref="GeneID:851208"
                     /db_xref="SGD:S000000023"
                     /translation="MSDEIVWQVINQSFCSHRIKAPNGQNFCRNEYNVTGLCTRQSCP
                     LANSKYATVKCDNGKLYLYMKTPERAHTPAKLWERIKLSKNYTKALQQIDEHLLHWSK
                     FFRHKCKQRFTKLTQVMITERRLALREEERHYVGVAPKVKRREQNRERKALVAAKIEK
                     AIEKELMDRLKSGAYGDKPLNVDEKVWKKIMGQMEEENSQDEEEDWDEEEESDDGEVE
                     YVADDGEGEYVDVDDLEKWLADSDREASSASESESDSESESDSDSDEENKNSAKRRKK
                     GTSAKTKRPKVEIEYEEEHEVQNAEQEVAQ"
     gene            complement(<101565..>105872)
                     /gene="LTE1"
                     /locus_tag="YAL024C"
                     /gene_synonym="MSI2"
                     /db_xref="GeneID:851209"
     mRNA            complement(<101565..>105872)
                     /gene="LTE1"
                     /locus_tag="YAL024C"
                     /gene_synonym="MSI2"
                     /product="mitotic regulator LTE1"
                     /transcript_id="NM_001178169.1"
                     /db_xref="GeneID:851209"
     CDS             complement(101565..105872)
                     /gene="LTE1"
                     /locus_tag="YAL024C"
                     /gene_synonym="MSI2"
                     /note="Protein similar to GDP/GTP exchange factors;
                     without detectable GEF activity; required for asymmetric
                     localization of Bfa1p at daughter-directed spindle pole
                     bodies and for mitotic exit at low temperatures"
                     /codon_start=1
                     /product="mitotic regulator LTE1"
                     /protein_id="NP_009378.1"
                     /db_xref="GeneID:851209"
                     /db_xref="SGD:S000000022"
                     /translation="MEIFSQKDYYPTPSSNVISYESDCVSKPVNSADLPALIVHLSSP
                     LEGVDYNASADFFLIYRNFITPQDLHDLLIYRFRWCIREITTNAAKAKRRRIGEVALV
                     RTFVLLRHSILNYFVQDFLPNITLRLRLIEFLNDKHIEQYPKIISSCIINLKKNWVHC
                     SKLVWENIELNEPDKLDFDAWLHYSLKDFTQLESLHKRGSRLSIYARQSFASPDFRNQ
                     SVLSLYKTSDVFRLPEKLQSSNSSKNQRSPSMLLFPDNTSNVYSKHRIAKEPSVDNES
                     EDMSDSKQKISHLSKVTLVSTLMKGVDYPSSYAVDKIMPPTPAKKVEFILNSLYIPED
                     LNEQSGTLQGTSTTSSLDNNSNSNSRSNTSSMSVLHRSAIGLLAKWMKNHNRHDSSND
                     KKFMSAIKPANQKPEMDAFVKYVVSISSLNRKSSKEEEEEFLNSDSSKFDILSARTID
                     EVESLLHLQNQLIEKVQTHSNNNRGPTVNVDCERREHIHDIKILQQNSFKPSNDNFSA
                     MDNLDLYQTVSSIAQSVISLTNTLNKQLQNNESNMQPSPSYDALQRRKVKSLTTAYYN
                     KMHGSYSAESMRLFDKDNSSSRTDENGPQRLLFHETDKTNSEAITNMTPRRKNHSQSQ
                     KSMTSSPLKNVLPDLKESSPLNDSREDTESITYSYDSELSSSSPPRDTVTKKSRKVRN
                     IVNNTDSPTLKTKTGFLNLREFTFEDTKSLDEKKSTIDGLEKNYDNKENQESEYESTK
                     KLDNSLDASSEANNYDITTRKKHSSCNHKIKQAVVRPASGRISISRVQSIAITPTKEL
                     SIVDPEQNKSNSVIEEISEIEPLNLEYNKKSALYSDTSSTVISISTSKLFESAQNSPL
                     KQTQNPQREFPNGTSVSETNRIRLSIAPTIESVVSDLNSITTGSTVETFETSRDLPVP
                     HQRIINLREEYQRGNQDIISNTSSLHELKTIDLSDSNNDLESPSTHAKNNKYFFSPDD
                     GSIDVASPMKNVEELKSKFLKNESETNSNISGSVLTMDDIDINDTSSARNTRRANSES
                     AFTGSLNKKNLNEIANMLDDSINDDPITVALMKLEGTYEKIPEKPENTKSSDAIGIKT
                     SKLADEVEMLNLNNLPSFQNSPAEKRKSLLIERRRQTIMNIPFTPDQSEKEGFTSSSP
                     EKIDVSANVDVAVQAAQIQELIGQYRIHDSRLMISNNESHVPFILMYDSLSVAQQMTL
                     IEKEILGEIDWKDLLDLKMKHEGPQVISWLQLLVRNETLSGIDLAISRFNLTVDWIIS
                     EILLTKSSKMKRNVIQRFIHVADHCRTFQNFNTLMEIILALSSSVVQKFTDAWRLIEP
                     GDLLTWEELKKIPSLDRNYSTIRNLLNSVNPLVGCVPFIVVYLSDLSANAEKKDWILE
                     DKVVNYNKFDTNVQIVKNFIQRVQWSKFYTFKVNHELLSKCVYISTLTQEEINELST"
     gene            complement(<106272..>108551)
                     /gene="PMT2"
                     /locus_tag="YAL023C"
                     /gene_synonym="FUN25"
                     /db_xref="GeneID:851210"
     mRNA            complement(<106272..>108551)
                     /gene="PMT2"
                     /locus_tag="YAL023C"
                     /gene_synonym="FUN25"
                     /product="dolichyl-phosphate-mannose-protein
                     mannosyltransferase PMT2"
                     /transcript_id="NM_001178168.1"
                     /db_xref="GeneID:851210"
     CDS             complement(106272..108551)
                     /gene="PMT2"
                     /locus_tag="YAL023C"
                     /gene_synonym="FUN25"
                     /EC_number="2.4.1.109"
                     /note="Protein O-mannosyltransferase of the ER membrane;
                     transfers mannose residues from dolichyl
                     phosphate-D-mannose to protein serine/threonine residues;
                     involved in ER quality control; acts in a complex with
                     Pmt1p, can instead interact with Pmt5p; antifungal drug
                     target; PMT2 has a paralog, PMT3, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="dolichyl-phosphate-mannose-protein
                     mannosyltransferase PMT2"
                     /protein_id="NP_009379.2"
                     /db_xref="GeneID:851210"
                     /db_xref="SGD:S000000021"
                     /translation="MSSSSSTGYSKNNAAHIKQENTLRQRESSSISVSEELSSADERD
                     AEDFSKEKPAAQSSLLRLESVVMPVIFTALALFTRMYKIGINNHVVWDEAHFGKFGSY
                     YLRHEFYHDVHPPLGKMLVGLSGYLAGYNGSWDFPSGEIYPDYLDYVKMRLFNASFSA
                     LCVPLAYFTAKAIGFSLPTVWLMTVLVLFENSYSTLGRFILLDSMLLFFTVASFFSFV
                     MFHNQRSKPFSRKWWKWLLITGISLGCTISVKMVGLFIITMVGIYTVIDLWTFLADKS
                     MSWKTYINHWLARIFGLIIVPFCIFLLCFKIHFDLLSHSGTGDANMPSLFQARLVGSD
                     VGQGPRDIALGSSVVSIKNQALGGSLLHSHIQTYPDGSNQQQVTCYGYKDANNEWFFN
                     RERGLPSWSENETDIEYLKPGTSYRLVHKSTGRNLHTHPVAAPVSKTQWEVSGYGDNV
                     VGDNKDNWVIEIMDQRGDEDPEKLHTLTTSFRIKNLEMGCYLAQTGNSLPEWGFRQQE
                     VVCMKNPFKRDKRTWWNIETHENERLPPRPEDFQYPKTNFLKDFIHLNLAMMATNNAL
                     VPDPDKFDYLASSAWQWPTLNVGLRLCGWGDDNPKYFLLGTPASTWASSVAVLAFMAT
                     VVILLIRWQRQYVDLRNPSNWNVFLMGGFYPLLAWGLHYMPFVIMSRVTYVHHYLPAL
                     YFALIILAYCFDAGLQKWSRSKCGRIMRFVLYAGFMALVIGCFWYFSPISFGMEGPSS
                     NFRYLNWFSTWDIADKQEA"
     gene            complement(<108877..>110430)
                     /gene="FUN26"
                     /locus_tag="YAL022C"
                     /db_xref="GeneID:851211"
     mRNA            complement(<108877..>110430)
                     /gene="FUN26"
                     /locus_tag="YAL022C"
                     /product="nucleoside transmembrane transporter FUN26"
                     /transcript_id="NM_001178167.1"
                     /db_xref="GeneID:851211"
     CDS             complement(108877..110430)
                     /gene="FUN26"
                     /locus_tag="YAL022C"
                     /note="High affinity, broad selectivity,
                     nucleoside/nucleobase transporter; vacuolar membrane
                     localized transporter which may regulate the balance of
                     nicotinamide riboside (NmR) levels between the cytosol and
                     vacuole, contributing to salvage of NmR for use in
                     cytosolic NAD+ synthesis; equilibrative nucleoside
                     transporter (ENT) family member"
                     /codon_start=1
                     /product="nucleoside transmembrane transporter FUN26"
                     /protein_id="NP_009380.1"
                     /db_xref="GeneID:851211"
                     /db_xref="SGD:S000000020"
                     /translation="MSTSADTDTIKKPILAVPEPALADTHSEEISRSGEEHESENNEH
                     SDEEGDNYSEREQSVSTEPLDTLPLRKKLKNLSYITFFAIGIGLLWPWNCILSASQYF
                     KHDIFKDTSIWAKIFTSSMMSFSTISSMLFNIYLAKRQYKYSRRVINGLVWEIIVFTV
                     MCFFTILHFLLPKWFNFMFIMMLVVISSMGTAMTQNGIMAIANVFGSEYSQGVMVGQA
                     VAGVLPSLVLFALAFIENSSVSTTGGILLYFFTTTLVVTICVVMFSVSKISRKVNENW
                     NVEDGHITDVLLGSLRSNEEEIRIVGRIDQMEDEDHRRTNGTRDDNDEGEELQLKVPF
                     EVLFAKLKYLVLSIFTTFVVTLVFPVFASATYVTGLPLSNAQYIPLIFTLWNLGDLYG
                     RVIADWPMFRDQKFTPRKTFIYSLLRVAAIPLFLMFTAITSSSSGDEEHNGSVIVDLC
                     YMLLQFLFGVTNGHVISMSFMKVPEQLDNDDEKEAAGGFTNIFVSTGLALGSIISYVF
                     VFIIDFIIR"
     gene            complement(<110846..>113359)
                     /gene="CCR4"
                     /locus_tag="YAL021C"
                     /gene_synonym="FUN27; NUT21"
                     /db_xref="GeneID:851212"
     mRNA            complement(<110846..>113359)
                     /gene="CCR4"
                     /locus_tag="YAL021C"
                     /gene_synonym="FUN27; NUT21"
                     /product="CCR4-NOT core exoribonuclease subunit CCR4"
                     /transcript_id="NM_001178166.1"
                     /db_xref="GeneID:851212"
     CDS             complement(110846..113359)
                     /gene="CCR4"
                     /locus_tag="YAL021C"
                     /gene_synonym="FUN27; NUT21"
                     /EC_number="3.1.13.4"
                     /note="Component of the CCR4-NOT transcriptional complex;
                     CCR4-NOT is involved in regulation of gene expression;
                     component of the major cytoplasmic deadenylase, which is
                     involved in mRNA poly(A) tail shortening"
                     /codon_start=1
                     /product="CCR4-NOT core exoribonuclease subunit CCR4"
                     /protein_id="NP_009381.1"
                     /db_xref="GeneID:851212"
                     /db_xref="SGD:S000000019"
                     /translation="MNDPSLLGYPNVGPQQQQQQQQQQHAGLLGKGTPNALQQQLHMN
                     QLTGIPPPGLMNNSDVHTSSNNNSRQLLDQLANGNANMLNMNMDNNNNNNNNNNNNNN
                     NGGGSGVMMNASTAAVNSIGMVPTVGTPVNINVNASNPLLHPHLDDPSLLNNPIWKLQ
                     LHLAAVSAQSLGQPNIYARQNAMKKYLATQQAQQAQQQAQQQAQQQVPGPFGPGPQAA
                     PPALQPTDFQQSHIAEASKSLVDCTKQALMEMADTLTDSKTAKKQQPTGDSTPSGTAT
                     NSAVSTPLTPKIELFANGKDEANQALLQHKKLSQYSIDEDDDIENRMVMPKDSKYDDQ
                     LWHALDLSNLQIFNISANIFKYDFLTRLYLNGNSLTELPAEIKNLSNLRVLDLSHNRL
                     TSLPAELGSCFQLKYFYFFDNMVTTLPWEFGNLCNLQFLGVEGNPLEKQFLKILTEKS
                     VTGLIFYLRDNRPEIPLPHERRFIEINTDGEPQREYDSLQQSTEHLATDLAKRTFTVL
                     SYNTLCQHYATPKMYRYTPSWALSWDYRRNKLKEQILSYDSDLLCLQEVESKTFEEYW
                     VPLLDKHGYTGIFHAKARAKTMHSKDSKKVDGCCIFFKRDQFKLITKDAMDFSGAWMK
                     HKKFQRTEDYLNRAMNKDNVALFLKLQHIPSGDTIWAVTTHLHWDPKFNDVKTFQVGV
                     LLDHLETLLKEETSHNFRQDIKKFPVLICGDFNSYINSAVYELINTGRVQIHQEGNGR
                     DFGYMSEKNFSHNLALKSSYNCIGELPFTNFTPSFTDVIDYIWFSTHALRVRGLLGEV
                     DPEYVSKFIGFPNDKFPSDHIPLLARFEFMKTNTGSKKV"
     gene            complement(<113614..>114615)
                     /gene="ATS1"
                     /locus_tag="YAL020C"
                     /gene_synonym="FUN28; KTI13"
                     /db_xref="GeneID:851213"
     mRNA            complement(<113614..>114615)
                     /gene="ATS1"
                     /locus_tag="YAL020C"
                     /gene_synonym="FUN28; KTI13"
                     /product="Ats1p"
                     /transcript_id="NM_001178165.2"
                     /db_xref="GeneID:851213"
     CDS             complement(113614..114615)
                     /gene="ATS1"
                     /locus_tag="YAL020C"
                     /gene_synonym="FUN28; KTI13"
                     /note="Protein required for modification of wobble
                     nucleosides in tRNA; acts with Elongator complex, Kti11p,
                     and Kti12p; has a potential role in regulatory
                     interactions between microtubules and the cell cycle;
                     forms a stable heterodimer with Kti11p"
                     /codon_start=1
                     /product="Ats1p"
                     /protein_id="NP_009382.2"
                     /db_xref="GeneID:851213"
                     /db_xref="SGD:S000000018"
                     /translation="MSCVYAFGSNGQRQLGLGHDEDMDTPQRSVPGDDGAIVRKIACG
                     GNHSVMLTNDGNLVGCGDNRRGELDSAQALRQVHDWRPVEVPAPVVDVACGWDTTVIV
                     DADGRVWQRGGGCYEFTQQHVPLNSNDERIAVYGCFQNFVVVQGTRVYGWGSNTKCQL
                     QEPKSRSLKEPVLVYDTGSVAVDYVAMGKDFMVIVDEGGRIVHASGRLPTGFELKQQQ
                     KRHNLVVLCMWTSIHLWNARLNTVESFGRGTHSQLFPQERLDFPIVGVATGSEHGILT
                     TANQEGKSHCYNVYCWGWGEHGNCGPQKGSQPGLQLVGQYSGKPRVFGGCATTWIVL"
     gene            <114919..>118314
                     /gene="FUN30"
                     /locus_tag="YAL019W"
                     /db_xref="GeneID:851214"
     mRNA            <114919..>118314
                     /gene="FUN30"
                     /locus_tag="YAL019W"
                     /product="DNA-dependent ATPase FUN30"
                     /transcript_id="NM_001178164.1"
                     /db_xref="GeneID:851214"
     CDS             114919..118314
                     /gene="FUN30"
                     /locus_tag="YAL019W"
                     /EC_number="3.6.4.12"
                     /note="Snf2p family member with ATP-dependent chromatin
                     remodeling activity; has a role in silencing at the mating
                     type locus, telomeres and centromeres; enriched at
                     centromeres and is required for correct chromatin
                     structure around centromeres, as well as at the boundary
                     element of the silent HMR; recruited to DNA double-strand
                     breaks (DSBs) where it promotes 5' strand resection of
                     DSBs; potential Cdc28p substrate"
                     /codon_start=1
                     /product="DNA-dependent ATPase FUN30"
                     /protein_id="NP_009383.1"
                     /db_xref="GeneID:851214"
                     /db_xref="SGD:S000000017"
                     /translation="MSGSHSNDEDDVVQVPETSSPTKVASSSPLKPTSPTVPDASVAS
                     LRSRFTFKPSDPSEGAHTSKPLPSGSPEVALVNLAREFPDFSQTLVQAVFKSNSFNLQ
                     SARERLTRLRQQRQNWTWNKNASPKKSETPPPVKKSLPLANTGRLSSIHGNINNKSSK
                     ITVAKQKTSIFDRYSNVINQKQYTFELPTNLNIDSEALSKLPVNYNKKRRLVRADQHP
                     IGKSYESSATQLGSAREKLLANRKYGRHANDNDEEEEESMMTDDDDASGDDYTESTPQ
                     INLDEQVLQFINDSDIVDLSDLSDTTMHKAQLIASHRPYSSLNAFVNTNFNDKDTEEN
                     ASNKRKRRAAASANESERLLDKITQSIRGYNAIESVIKKCSSYGDLVTSQMKKWGVQV
                     EGDNSELDLMNLGEDDDDDNDDGNNDNNNSNNNNTAGADATSKEKEDTKAVVEGFDET
                     SAEPTPAPAPAPVERETKRIRNTTKPKVVEDEDDDVDLEAIDDELPQSEHEDDDYEEE
                     DEDYNDEEEDVEYDDGDDDDDDDDEFVATRKNTHVISTTSRNGRKPIVKFFKGKPRLL
                     SPEISLKDYQQTGINWLNLLYQNKMSCILADDMGLGKTCQVISFFAYLKQINEPGPHL
                     VVVPSSTLENWLREFQKFAPALKIEPYYGSLQEREELRDILERNAGKYDVIVTTYNLA
                     AGNKYDVSFLKNRNFNVVVYDEGHMLKNSTSERFAKLMKIRANFRLLLTGTPLQNNLK
                     ELMSLLEFIMPNLFISKKESFDAIFKQRAKTTDDNKNHNPLLAQEAITRAKTMMKPFI
                     LRRRKDQVLKHLPPKHTHIQYCELNAIQKKIYDKEIQIVLEHKRMIKDGELPKDAKEK
                     SKLQSSSSKNLIMALRKASLHPLLFRNIYNDKIITKMSDAILDEPAYAENGNKEYIKE
                     DMSYMTDFELHKLCCNFPNTLSKYQLHNDEWMQSGKIDALKKLLKTIIVDKQEKVLIF
                     SLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLIDKFYEDKDIPIFILSTKAGGF
                     GINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIEEKIHQLAK
                     NKLALDSYISEDKKSQDVLESKVSDMLEDIIYDENSKPKGTKE"
     gene            complement(<118564..>119541)
                     /gene="LDS1"
                     /locus_tag="YAL018C"
                     /db_xref="GeneID:851215"
     mRNA            complement(<118564..>119541)
                     /gene="LDS1"
                     /locus_tag="YAL018C"
                     /product="Lds1p"
                     /transcript_id="NM_001178163.1"
                     /db_xref="GeneID:851215"
     CDS             complement(118564..119541)
                     /gene="LDS1"
                     /locus_tag="YAL018C"
                     /note="Protein Involved in spore wall assembly; localizes
                     to lipid droplets found on or outside of the prospore
                     membrane; shares similarity with Lds2p and Rrt8p, and a
                     strain mutant for all 3 genes exhibits reduced dityrosine
                     fluorescence relative to the single mutants"
                     /codon_start=1
                     /product="Lds1p"
                     /protein_id="NP_009384.1"
                     /db_xref="GeneID:851215"
                     /db_xref="SGD:S000000016"
                     /translation="MSFTGSLALAGIGGLVYKFGGGQSYEKLPYVNIPFNQYLDKVYK
                     KHFSKVMSRTRYVLMNFFKDAFTGGAFMYPFKGFLEFNTNKSSYSTTMLGILSSYLIM
                     FALVSFVYWATITPMYTAFLIVLGPIGLFIAIFHSFLQANVFTLLFMRLSHFNNHLVE
                     VCLEKNGLEENLSEVKPIKYYAPINSIYFWAYYFPFKLVKYMLGLSVLFVLLVISFFP
                     LIGPILFHILISPFITQIYFTKVLRLQNFDNIQRRENIYLHAGQYASFGFLAGLIESV
                     PILAGFAISTNTIGSVLFNLDHPMVPENLVETQAEIEAAPQDINQQPNQ"
     gene            <120225..>124295
                     /gene="PSK1"
                     /locus_tag="YAL017W"
                     /gene_synonym="FUN31"
                     /db_xref="GeneID:851216"
     mRNA            <120225..>124295
                     /gene="PSK1"
                     /locus_tag="YAL017W"
                     /gene_synonym="FUN31"
                     /product="serine/threonine protein kinase PSK1"
                     /transcript_id="NM_001178162.2"
                     /db_xref="GeneID:851216"
     CDS             120225..124295
                     /gene="PSK1"
                     /locus_tag="YAL017W"
                     /gene_synonym="FUN31"
                     /EC_number="2.7.11.1"
                     /note="PAS domain-containing serine/threonine protein
                     kinase; coordinately regulates protein synthesis and
                     carbohydrate metabolism and storage in response to a
                     unknown metabolite that reflects nutritional status; PSK1
                     has a paralog, PSK2, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="serine/threonine protein kinase PSK1"
                     /protein_id="NP_009385.2"
                     /db_xref="GeneID:851216"
                     /db_xref="SGD:S000000015"
                     /translation="MPYIGASNLSEHSFVNLKEKHAITHKGTSSSVASLQTPPSPDQE
                     NHIDNELENYDTSLSDVSTPNKKEGDEFEQSLRDTFASFRKTKPPPPLDFEQPRLPST
                     ASSSVDSTVSSPLTDEDIKELEFLPNESTHSYSYNPLSPNSLAVRLRILKRSLEIIIQ
                     NPSMLLEPTPDDLPPLKEFAGRRSSLPRTSASANHLMNRNKSQIWNTTSATLNAFVNN
                     TSSSSAASSALSNKKPGTPVFPNLDPTHSQTFHRANSLAYLPSILPEQDPLLKHNNSL
                     FRGDYGNNISPERPSFRQPFKDQTSNLRNSSLLNERAYQEDETFLPHHGPSMDLLNEQ
                     RANLKSLLNLLNETLEKNTSERASDLHMISLFNLNKLMLGDPKKNNSERDKRTEKLKK
                     ILLDSLAEPFFEHYNFIGDNPIADTDELKEEIDEFTGSGDTTAITDIRPQQDYGRILR
                     TFTSTKNSAPQAIFTCSQEDPWQFRAANDLACLVFGISQNAIRALTLMDLIHTDSRNF
                     VLHKLLSTEGQEMVFTGEIIGIVQPETLSSSKVVWASFWAKRKNGLLVCVFEKVPCDY
                     VDVLLNLDDFGAENIVDKCELLSDGPTLSSSSTLSLPKMASSPTGSKLEYSLERKILE
                     KSYTKPTSTENRNGDENQLDGDSHSEPSLSSSPVRSKKSVKFANDIKDVKSISQSLAK
                     LMDDVRNGVVFDPDDDLLPMPIKVCNHINETRYFTLNHLSYNIPCAVSSTVLEDELKL
                     KIHSLPYQAGLFIVDSHTLDIVSSNKSILKNMFGYHFAELVGKSITEIIPSFPKFLQF
                     INDKYPALDITLHKNKGLVLTEHFFRKIQAEIMGDRKSFYTSVGIDGLHRDGCEIKID
                     FQLRVMNSKVILLWVTHSRDVVFEEYNTNPSQLKMLKESELSLMSSASSSASSSKKSS
                     SRISTGTLKDMSNLSTYEDLAHRTNKLKYEIGDDSRAHSQSTLSEQEQVPLENDKDSG
                     EMMLADPEMKHKLELARIYSRDKSQFVKEGNFKVDENLIISKISLSPSTESLADSKSS
                     GKGLSPLEEEKLIDENATENGLAGSPKDEDGIIMTNKRGNQPVSTFLRTPEKNIGAQK
                     HVKKFSDFVSLQKMGEGAYGKVNLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTI
                     PSEIQIMATLNKKPHENILRLLDFFEDDDYYYIETPVHGETGCIDLFDLIEFKTNMTE
                     FEAKLIFKQVVAGIKHLHDQGIVHRDIKDENVIVDSKGFVKIIDFGSAAYVKSGPFDV
                     FVGTIDYAAPEVLGGNPYEGQPQDIWAIGILLYTVVFKENPFYNIDEILEGDLKFNNA
                     EEVSEDCIELIKSILNRCVPKRPTIDDINNDKWLVI"
     rep_origin      124349..124597
                     /note="ARS107;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000118319"
     gene            <124879..>126786
                     /gene="TPD3"
                     /locus_tag="YAL016W"
                     /gene_synonym="FUN32"
                     /db_xref="GeneID:851217"
     mRNA            <124879..>126786
                     /gene="TPD3"
                     /locus_tag="YAL016W"
                     /gene_synonym="FUN32"
                     /product="protein phosphatase 2A structural subunit TPD3"
                     /transcript_id="NM_001178161.1"
                     /db_xref="GeneID:851217"
     CDS             124879..126786
                     /gene="TPD3"
                     /locus_tag="YAL016W"
                     /gene_synonym="FUN32"
                     /note="Regulatory subunit A of the heterotrimeric PP2A
                     complex; the heterotrimeric protein phosphatase 2A (PP2A)
                     complex also contains regulatory subunit Cdc55p and either
                     catalytic subunit Pph21p or Pph22p; required for cell
                     morphogenesis and transcription by RNA polymerase III"
                     /codon_start=1
                     /product="protein phosphatase 2A structural subunit TPD3"
                     /protein_id="NP_009386.1"
                     /db_xref="GeneID:851217"
                     /db_xref="SGD:S000000014"
                     /translation="MSGARSTTAGAVPSAATTSTTSTTSNSKDSDSNESLYPLALLMD
                     ELKHDDIANRVEAMKKLDTIALALGPERTRNELIPFLTEVAQDDEDEVFAVLAEQLGK
                     FVPYIGGPQYATILLPVLEILASAEETLVREKAVDSLNNVAQELSQEQLFSDFVPLIE
                     HLATADWFSSKVSACGLFKSVIVRIKDDSLRKNILALYLQLAQDDTPMVKRAVGKNLP
                     ILIDLLTQNLGLSTDEDWDYISNIFQKIINDNQDSVKFLAVDCLISILKFFNAKGDES
                     HTQDLLNSAVKLIGDEAWRVRYMAADRFSDLASQFSSNQAYIDELVQPFLNLCEDNEG
                     DVREAVAKQVSGFAKFLNDPSIILNKILPAVQNLSMDESETVRSALASKITNIVLLLN
                     KDQVINNFLPILLNMLRDEFPDVRLNIIASLKVVNDVIGIELLSDSLLPAITELAKDV
                     NWRVRMAIIEYIPILAEQLGMQFFDQQLSDLCLSWLWDTVYSIREAAVNNLKRLTEIF
                     GSDWCRDEIISRLLKFDLQLLENFVSRFTILSALTTLVPVVSLDVVTEQLLPFISHLA
                     DDGVPNIRFNVAKSYAVIVKVLIKDEAKYDALIKNTILPSLQTLCQDEDVDVKYFAKK
                     SLAECQELLKN"
     gene            complement(<126903..>128102)
                     /gene="NTG1"
                     /locus_tag="YAL015C"
                     /gene_synonym="FUN33; ogg2; SCR1"
                     /db_xref="GeneID:851218"
     mRNA            complement(<126903..>128102)
                     /gene="NTG1"
                     /locus_tag="YAL015C"
                     /gene_synonym="FUN33; ogg2; SCR1"
                     /product="bifunctional N-glycosylase/AP lyase NTG1"
                     /transcript_id="NM_001178160.1"
                     /db_xref="GeneID:851218"
     CDS             complement(126903..128102)
                     /gene="NTG1"
                     /locus_tag="YAL015C"
                     /gene_synonym="FUN33; ogg2; SCR1"
                     /EC_number="3.2.2.-"
                     /EC_number="4.2.99.18"
                     /note="DNA N-glycosylase and apurinic/apyrimidinic (AP)
                     lyase; involved in base excision repair; acts in both
                     nucleus and mitochondrion; creates a double-strand break
                     at mtDNA origins that stimulates replication in response
                     to oxidative stress; required for maintaining
                     mitochondrial genome integrity; NTG1 has a paralog, NTG2,
                     that arose from the whole genome duplication"
                     /codon_start=1
                     /product="bifunctional N-glycosylase/AP lyase NTG1"
                     /protein_id="NP_009387.1"
                     /db_xref="GeneID:851218"
                     /db_xref="SGD:S000000013"
                     /translation="MQKISKYSSMAILRKRPLVKTETGPESELLPEKRTKIKQEEVVP
                     QPVDIDWVKSLPNKQYFEWIVVRNGNVPNRWATPLDPSILVTPASTKVPYKFQETYAR
                     MRVLRSKILAPVDIIGGSSIPVTVASKCGISKEQISPRDYRLQVLLGVMLSSQTKDEV
                     TAMAMLNIMRYCIDELHSEEGMTLEAVLQINETKLDELIHSVGFHTRKAKYILSTCKI
                     LQDQFSSDVPATINELLGLPGVGPKMAYLTLQKAWGKIEGICVDVHVDRLTKLWKWVD
                     AQKCKTPDQTRTQLQNWLPKGLWTEINGLLVGFGQIITKSRNLGDMLQFLPPDDPRSS
                     LDWDLQSQLYKEIQQNIMSYPKWVKYLEGKRELNVEAEINVKHEEKTVEETMVKLEND
                     ISVKVED"
     gene            complement(<128252..>129019)
                     /gene="SYN8"
                     /locus_tag="YAL014C"
                     /gene_synonym="SLT2; UIP2"
                     /db_xref="GeneID:851219"
     mRNA            complement(<128252..>129019)
                     /gene="SYN8"
                     /locus_tag="YAL014C"
                     /gene_synonym="SLT2; UIP2"
                     /product="syntaxin"
                     /transcript_id="NM_001178159.1"
                     /db_xref="GeneID:851219"
     CDS             complement(128252..129019)
                     /gene="SYN8"
                     /locus_tag="YAL014C"
                     /gene_synonym="SLT2; UIP2"
                     /note="Endosomal SNARE related to mammalian syntaxin 8"
                     /codon_start=1
                     /product="syntaxin"
                     /protein_id="NP_009388.2"
                     /db_xref="GeneID:851219"
                     /db_xref="SGD:S000000012"
                     /translation="MDVLKLGYELDQLSDLVEERTRLVSVLKLAPTSNDNVTLKRQLG
                     SILELLQKCAPNDELISRYNTILDKIPDTAVDKELYRFQQQVARNTDEVSKESLKKVR
                     FKNDDELTVMYKDDDEQDEESPLPSTHTPYKDEPLQSQLQSQSQPQPPQPMVSNQELF
                     INQQQQLLEQDSHLGALSQSIGRTHDISLDLNNEIVSQNDSLLVDLENLIDNNGRNLN
                     RASRSMHGFNNSRFKDNGNCVIILVLIVVLLLLLLVL"
     gene            <129270..>130487
                     /gene="DEP1"
                     /locus_tag="YAL013W"
                     /gene_synonym="FUN54"
                     /db_xref="GeneID:851220"
     mRNA            <129270..>130487
                     /gene="DEP1"
                     /locus_tag="YAL013W"
                     /gene_synonym="FUN54"
                     /product="Rpd3L histone deacetylase complex subunit DEP1"
                     /transcript_id="NM_001178158.2"
                     /db_xref="GeneID:851220"
     CDS             129270..130487
                     /gene="DEP1"
                     /locus_tag="YAL013W"
                     /gene_synonym="FUN54"
                     /note="Component of the Rpd3L histone deacetylase complex;
                     required for diauxic shift-induced histone H2B deposition
                     onto rDNA genes; transcriptional modulator involved in
                     regulation of structural phospholipid biosynthesis genes
                     and metabolically unrelated genes, as well as maintenance
                     of telomeres, mating efficiency, and sporulation"
                     /codon_start=1
                     /product="Rpd3L histone deacetylase complex subunit DEP1"
                     /protein_id="NP_009389.3"
                     /db_xref="GeneID:851220"
                     /db_xref="SGD:S000000011"
                     /translation="MSQQTPQESEQTTAKEQDLDQESVLSNIDFNTDLNHNLNLSEYC
                     ISSDAGTEKMDSDEEKSLANLPELKYAPKLSSLVKQETLTESLKRPHEDEKEAIDEAK
                     KMKVPGENEDESKEEEKSQELEEAIDSKEKSTDARDEQGDEGDNEEENNEEDNENENE
                     HTAPPALVMPSPIEMEEQRMTALKEITDIEYKFAQLRQKLYDNQLVRLQTELQMCLEG
                     SHPELQVYYSKIAAIRDYKLHRAYQRQKYELSCINTETIATRTFIHQDFHKKVTDLRA
                     RLLNRTTQTWYDINKERRDMDIVIPDVNYHVPIKLDNKTLSCITGYASAAQLCYPGEP
                     VAEDLACESIEYRYRANPVDKLEVIVDRMRLNNEISDLEGLRKYFHSFPGAPELNPLR
                     DSEINDDFHQWAQ"
     gene            <130799..>131983
                     /gene="CYS3"
                     /locus_tag="YAL012W"
                     /gene_synonym="CYI1; FUN35; STR1"
                     /db_xref="GeneID:851221"
     mRNA            <130799..>131983
                     /gene="CYS3"
                     /locus_tag="YAL012W"
                     /gene_synonym="CYI1; FUN35; STR1"
                     /product="cystathionine gamma-lyase CYS3"
                     /transcript_id="NM_001178157.1"
                     /db_xref="GeneID:851221"
     CDS             130799..131983
                     /gene="CYS3"
                     /locus_tag="YAL012W"
                     /gene_synonym="CYI1; FUN35; STR1"
                     /EC_number="4.4.1.1"
                     /note="Cystathionine gamma-lyase; catalyzes one of the two
                     reactions involved in the transsulfuration pathway that
                     yields cysteine from homocysteine with the intermediary
                     formation of cystathionine; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="cystathionine gamma-lyase CYS3"
                     /protein_id="NP_009390.1"
                     /db_xref="GeneID:851221"
                     /db_xref="SGD:S000000010"
                     /translation="MTLQESDKFATKAIHAGEHVDVHGSVIEPISLSTTFKQSSPANP
                     IGTYEYSRSQNPNRENLERAVAALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGD
                     VYGGTHRYFTKVANAHGVETSFTNDLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQK
                     VADLIKKHAAGQDVILVVDNTFLSPYISNPLNFGADIVVHSATKYINGHSDVVLGVLA
                     TNNKPLYERLQFLQNAIGAIPSPFDAWLTHRGLKTLHLRVRQAALSANKIAEFLAADK
                     ENVVAVNYPGLKTHPNYDVVLKQHRDALGGGMISFRIKGGAEAASKFASSTRLFTLAE
                     SLGGIESLLEVPAVMTHGGIPKEAREASGVFDDLVRISVGIEDTDDLLEDIKQALKQA
                     TN"
     gene            <132199..>134076
                     /gene="SWC3"
                     /locus_tag="YAL011W"
                     /gene_synonym="SWC1"
                     /db_xref="GeneID:851222"
     mRNA            <132199..>134076
                     /gene="SWC3"
                     /locus_tag="YAL011W"
                     /gene_synonym="SWC1"
                     /product="Swc3p"
                     /transcript_id="NM_001178156.1"
                     /db_xref="GeneID:851222"
     CDS             132199..134076
                     /gene="SWC3"
                     /locus_tag="YAL011W"
                     /gene_synonym="SWC1"
                     /note="hypothetical protein; component of the SWR1
                     complex, which exchanges histone variant H2AZ (Htz1p) for
                     chromatin-bound histone H2A; required for formation of
                     nuclear-associated array of smooth endoplasmic reticulum
                     known as karmellae"
                     /codon_start=1
                     /product="Swc3p"
                     /protein_id="NP_009391.2"
                     /db_xref="GeneID:851222"
                     /db_xref="SGD:S000000009"
                     /translation="MPAVLRTRSKESSIEQKPASRTRTRSRRGKRGRDDDDDDDDEES
                     DDAYDEVGNDYDEYASRAKLATNRPFEIVAGLPASVELPNYNSSLTHPQSIKNSGVLY
                     DSLVSSRRTWVQGEMFELYWRRPKKIVSESTPAATESPTSGTIPLIRDKMQKMCDCVM
                     SGGPHTFKVRLFILKNDKIEQKWQDEQELKKKEKELKRKNDAEAKRLRMEERKRQQMQ
                     KKIAKEQKLQLQKENKAKQKLEQEALKLKRKEEMKKLKEQNKNKQGSPSSSMHDPRMI
                     MNLNLMAQEDPKLNTLMETVAKGLANNSQLEEFKKFIEIAKKRSLEENPVNKRPSVTT
                     TRPAPPSKAKDVAEDHRLNSITLVKSSKTAATEPEPKKADDENAEKQQSKEAKTTAES
                     TQVDVKKEEEDVKEKGVKSEDTQKKEDNQVVPKRKRRKNAIKEDKDMQLTAFQQKYVQ
                     GAEIILEYLEFTHSRYYLPKKSVVEFLEDTDEIIISWIVIHNSKEIEKFKTKKIKAKL
                     KADQKLNKEDAKPGSDVEKEVSFNPLFEADCPTPLYTPMTMKLSGIHKRFNQIIRNSV
                     SPMEEVVKEMEKILQIGTRLSGYNLWYQLDGYDDEALSESLRFELNEWEHAMRSRRHK
                     R"
     gene            complement(<134184..>135665)
                     /gene="MDM10"
                     /locus_tag="YAL010C"
                     /gene_synonym="FUN37"
                     /db_xref="GeneID:851223"
     mRNA            complement(<134184..>135665)
                     /gene="MDM10"
                     /locus_tag="YAL010C"
                     /gene_synonym="FUN37"
                     /product="Mdm10p"
                     /transcript_id="NM_001178155.2"
                     /db_xref="GeneID:851223"
     CDS             complement(134184..135665)
                     /gene="MDM10"
                     /locus_tag="YAL010C"
                     /gene_synonym="FUN37"
                     /note="Subunit of both the ERMES and the SAM complex;
                     component of ERMES complex which acts as a molecular
                     tether between the mitochondria and the ER, necessary for
                     efficient phospholipid exchange between organelles and for
                     mitophagy; SAM/TOB complex component that functions in the
                     assembly of outer membrane beta-barrel proteins; involved
                     in mitochondrial inheritance and morphology; ERMES complex
                     is often co-localized with peroxisomes and concentrated
                     areas of pyruvate dehydrogenase"
                     /codon_start=1
                     /product="Mdm10p"
                     /protein_id="NP_009392.2"
                     /db_xref="GeneID:851223"
                     /db_xref="SGD:S000000008"
                     /translation="MLPYMDQVLRAFYQSTHWSTQNSYEDITATSRTLLDFRIPSAIH
                     LQISNKSTPNTFNSLDFSTRSRINGSLSYLYSDAQQLEKFMRNSTDIPLQDATETYRQ
                     LQPNLNFSVSSANTLSSDNTTVDNDKKLLHDSKFVKKSLYYGRMYYPSSDLEAMIIKR
                     LSPQTQFMLKGVSSFKESLNVLTCYFQRDSHRNLQEWIFSTSDLLCGYRVLHNFLTTP
                     SKFNTSLYNNSSLSLGAEFWLGLVSLSPGCSTTLRYYTHSTNTGRPLTLTLSWNPLFG
                     HISSTYSAKTGTNSTFCAKYDFNLYSIESNLSFGCEFWQKKHHLLETNKNNNDKLEPI
                     SDELVDINPNSRATKLLHENVPDLNSAVNDIPSTLDIPVHKQKLLNDLTYAFSSSLRK
                     IDEERSTIEKFDNKINSSIFTSVWKLSTSLRDKTLKLLWEGKWRGFLISAGTELVFTR
                     GFQESLSDDEKNDNAISISATDTENGNIPVFPAKFGIQFQYST"
     gene            <135854..>136633
                     /gene="SPO7"
                     /locus_tag="YAL009W"
                     /db_xref="GeneID:851224"
     mRNA            <135854..>136633
                     /gene="SPO7"
                     /locus_tag="YAL009W"
                     /product="Nem1-Spo7 phosphatase regulatory subunit SPO7"
                     /transcript_id="NM_001178154.1"
                     /db_xref="GeneID:851224"
     CDS             135854..136633
                     /gene="SPO7"
                     /locus_tag="YAL009W"
                     /note="Putative regulatory subunit of Nem1p-Spo7p
                     phosphatase holoenzyme; regulates nuclear growth by
                     controlling phospholipid biosynthesis, required for normal
                     nuclear envelope morphology, premeiotic replication, and
                     sporulation"
                     /codon_start=1
                     /product="Nem1-Spo7 phosphatase regulatory subunit SPO7"
                     /protein_id="NP_009393.1"
                     /db_xref="GeneID:851224"
                     /db_xref="SGD:S000000007"
                     /translation="MEPESIGDVGNHAQDDSASIVSGPRRRSTSKTSSAKNIRNSSNI
                     SPASMIFRNLLILEDDLRRQAHEQKILKWQFTLFLASMAGVGAFTFYELYFTSDYVKG
                     LHRVILQFTLSFISITVVLFHISGQYRRTIVIPRRFFTSTNKGIRQFNVKLVKVQSTW
                     DEKYTDSVRFVSRTIAYCNIYCLKKFLWLKDDNAIVKFWKSVTIQSQPRIGAVDVKLV
                     LNPRAFSAEIREGWEIYRDEFWAREGARRRKQAHELRPKSE"
     gene            <136914..>137510
                     /gene="FUN14"
                     /locus_tag="YAL008W"
                     /gene_synonym="MCP3"
                     /db_xref="GeneID:851225"
     mRNA            <136914..>137510
                     /gene="FUN14"
                     /locus_tag="YAL008W"
                     /gene_synonym="MCP3"
                     /product="Fun14p"
                     /transcript_id="NM_001178153.1"
                     /db_xref="GeneID:851225"
     CDS             136914..137510
                     /gene="FUN14"
                     /locus_tag="YAL008W"
                     /gene_synonym="MCP3"
                     /note="Integral mitochondrial outer membrane (MOM)
                     protein; dosage suppressor of an MDM10 null that reduces
                     ERMES-related phenotypes, such as alterations in
                     mitochondrial morphology, protein complex assembly, and
                     lipid profile; dosage suppressor of MDM12, MDM34, and MMM1
                     null mutant growth defects; novel mechanism of MOM import
                     involving Tom70p, the TOM complex, and the TIM23 complex,
                     requiring mitochondrial membrane potential and processing
                     by the IMP complex for correct biogenesis"
                     /codon_start=1
                     /product="Fun14p"
                     /protein_id="NP_009394.1"
                     /db_xref="GeneID:851225"
                     /db_xref="SGD:S000000006"
                     /translation="MTLAFNMQRLVFRNLNVGKRMFKNVPLWRFNVANKLGKPLTRSV
                     GLGGAGIVAGGFYLMNRQPSKLIFNDSLGAAVKQQGPLEPTVGNSTAITEERRNKISS
                     HKQMFLGSLFGVVLGVTVAKISILFMYVGITSMLLCEWLRYKGWIRINLKNIKSVIVL
                     KDVDLKKLLIDGLLGTEYMGFKVFFTLSFVLASLNANK"
     gene            complement(<137698..>138345)
                     /gene="ERP2"
                     /locus_tag="YAL007C"
                     /db_xref="GeneID:851226"
     mRNA            complement(<137698..>138345)
                     /gene="ERP2"
                     /locus_tag="YAL007C"
                     /product="Erp2p"
                     /transcript_id="NM_001178152.1"
                     /db_xref="GeneID:851226"
     CDS             complement(137698..138345)
                     /gene="ERP2"
                     /locus_tag="YAL007C"
                     /note="Member of the p24 family involved in ER to Golgi
                     transport; similar to Emp24p and Erv25p; role in misfolded
                     protein quality control; forms a heterotrimeric complex
                     with Erp1p, Emp24p, and Erv25p; localized to COPII-coated
                     vesicles; ERP2 has a paralog, ERP4, that arose from the
                     whole genome duplication"
                     /codon_start=1
                     /product="Erp2p"
                     /protein_id="NP_009395.1"
                     /db_xref="GeneID:851226"
                     /db_xref="SGD:S000000005"
                     /translation="MIKSTIALPSFFIVLILALVNSVAASSSYAPVAISLPAFSKECL
                     YYDMVTEDDSLAVGYQVLTGGNFEIDFDITAPDGSVITSEKQKKYSDFLLKSFGVGKY
                     TFCFSNNYGTALKKVEITLEKEKTLTDEHEADVNNDDIIANNAVEEIDRNLNKITKTL
                     NYLRAREWRNMSTVNSTESRLTWLSILIIIIIAVISIAQVLLIQFLFTGRQKNYV"
     repeat_region   complement(138831..138992)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006786"
     gene            139152..139254
                     /gene="TRN1"
                     /locus_tag="tP(UGG)A"
                     /db_xref="GeneID:851227"
     tRNA            join(139152..139187,139219..139254)
                     /gene="TRN1"
                     /locus_tag="tP(UGG)A"
                     /product="tRNA-Pro"
                     /note="Proline tRNA (tRNA-Pro), predicted by tRNAscan-SE
                     analysis; target of K. lactis zymocin; can mutate to
                     suppress +1 frameshift mutations in proline codons"
                     /db_xref="GeneID:851227"
                     /db_xref="SGD:S000006680"
     gene            complement(<139503..>141431)
                     /gene="SSA1"
                     /locus_tag="YAL005C"
                     /gene_synonym="YG100"
                     /db_xref="GeneID:851259"
     mRNA            complement(<139503..>141431)
                     /gene="SSA1"
                     /locus_tag="YAL005C"
                     /gene_synonym="YG100"
                     /product="Hsp70 family ATPase SSA1"
                     /transcript_id="NM_001178151.1"
                     /db_xref="GeneID:851259"
     CDS             complement(139503..141431)
                     /gene="SSA1"
                     /locus_tag="YAL005C"
                     /gene_synonym="YG100"
                     /note="ATPase involved in protein folding and NLS-directed
                     nuclear transport; member of HSP70 family; required for
                     ubiquitin-dependent degradation of short-lived proteins;
                     forms chaperone complex with Ydj1p; localized to nucleus,
                     cytoplasm, cell wall; 98% identical to paralog Ssa2p with
                     different functional specificity in propagation of yeast
                     [URE3] prions, vacuolar-mediated degradations of
                     gluconeogenesis enzymes; general targeting factor of
                     Hsp104p to prion fibrils"
                     /codon_start=1
                     /product="Hsp70 family ATPase SSA1"
                     /protein_id="NP_009396.2"
                     /db_xref="GeneID:851259"
                     /db_xref="SGD:S000000004"
                     /translation="MSKAVGIDLGTTYSCVAHFANDRVDIIANDQGNRTTPSFVAFTD
                     TERLIGDAAKNQAAMNPSNTVFDAKRLIGRNFNDPEVQADMKHFPFKLIDVDGKPQIQ
                     VEFKGETKNFTPEQISSMVLGKMKETAESYLGAKVNDAVVTVPAYFNDSQRQATKDAG
                     TIAGLNVLRIINEPTAAAIAYGLDKKGKEEHVLIFDLGGGTFDVSLLSIEDGIFEVKA
                     TAGDTHLGGEDFDNRLVNHFIQEFKRKNKKDLSTNQRALRRLRTACERAKRTLSSSAQ
                     TSVEIDSLFEGIDFYTSITRARFEELCADLFRSTLDPVEKVLRDAKLDKSQVDEIVLV
                     GGSTRIPKVQKLVTDYFNGKEPNRSINPDEAVAYGAAVQAAILTGDESSKTQDLLLLD
                     VAPLSLGIETAGGVMTKLIPRNSTIPTKKSEIFSTYADNQPGVLIQVFEGERAKTKDN
                     NLLGKFELSGIPPAPRGVPQIEVTFDVDSNGILNVSAVEKGTGKSNKITITNDKGRLS
                     KEDIEKMVAEAEKFKEEDEKESQRIASKNQLESIAYSLKNTISEAGDKLEQADKDTVT
                     KKAEETISWLDSNTTASKEEFDDKLKELQDIANPIMSKLYQAGGAPGGAAGGAPGGFP
                     GGAPPAPEAEGPTVEEVD"
     gene            <142174..>143160
                     /gene="EFB1"
                     /locus_tag="YAL003W"
                     /gene_synonym="TEF5"
                     /db_xref="GeneID:851260"
     mRNA            join(<142174..142253,142620..>143160)
                     /gene="EFB1"
                     /locus_tag="YAL003W"
                     /gene_synonym="TEF5"
                     /product="translation elongation factor 1 subunit beta"
                     /transcript_id="NM_001178150.1"
                     /db_xref="GeneID:851260"
     CDS             join(142174..142253,142620..143160)
                     /gene="EFB1"
                     /locus_tag="YAL003W"
                     /gene_synonym="TEF5"
                     /note="Translation elongation factor 1 beta; stimulates
                     nucleotide exchange to regenerate EF-1 alpha-GTP for the
                     next elongation cycle; part of the EF-1 complex, which
                     facilitates binding of aminoacyl-tRNA to the ribosomal A
                     site; human homolog EEF1B2 can complement yeast efb1
                     mutants"
                     /codon_start=1
                     /product="translation elongation factor 1 subunit beta"
                     /protein_id="NP_009398.1"
                     /db_xref="GeneID:851260"
                     /db_xref="SGD:S000000003"
                     /translation="MASTDFSKIETLKQLNASLADKSYIEGTAVSQADVTVFKAFQSA
                     YPEFSRWFNHIASKADEFDSFPAASAAAAEEEEDDDVDLFGSDDEEADAEAEKLKAER
                     IAAYNAKKAAKPAKPAAKSIVTLDVKPWDDETNLEEMVANVKAIEMEGLTWGAHQFIP
                     IGFGIKKLQINCVVEDDKVSLDDLQQSIEEDEDHVQSTDIAAMQKL"
     gene            142367..142468
                     /locus_tag="snR18"
                     /db_xref="GeneID:9164867"
     ncRNA           142367..142468
                     /ncRNA_class="snoRNA"
                     /locus_tag="snR18"
                     /product="SNR18"
                     /note="C/D box small nucleolar RNA (snoRNA); commonly
                     referred to as U18; guides 2'-O-methylation of large
                     subunit (LSU) rRNA at positions A649 and C650"
                     /transcript_id="NR_132150.1"
                     /db_xref="GeneID:9164867"
                     /db_xref="SGD:S000007500"
     gene            <143707..>147531
                     /gene="VPS8"
                     /locus_tag="YAL002W"
                     /gene_synonym="FUN15; VPL8; VPT8"
                     /db_xref="GeneID:851261"
     mRNA            <143707..>147531
                     /gene="VPS8"
                     /locus_tag="YAL002W"
                     /gene_synonym="FUN15; VPL8; VPT8"
                     /product="CORVET complex membrane-binding subunit VPS8"
                     /transcript_id="NM_001178149.1"
                     /db_xref="GeneID:851261"
     CDS             143707..147531
                     /gene="VPS8"
                     /locus_tag="YAL002W"
                     /gene_synonym="FUN15; VPL8; VPT8"
                     /note="Membrane-binding component of the CORVET complex;
                     involved in endosomal vesicle tethering and fusion in the
                     endosome to vacuole protein targeting pathway; interacts
                     with Vps21p; contains RING finger motif"
                     /codon_start=1
                     /product="CORVET complex membrane-binding subunit VPS8"
                     /protein_id="NP_009399.2"
                     /db_xref="GeneID:851261"
                     /db_xref="SGD:S000000002"
                     /translation="MEQNGLDHDSRSSIDTTINDTQKTFLEFRSYTQLSEKLASSSSY
                     TAPPLNEDGPKGVASAVSQGSESVVSWTTLTHVYSILGAYGGPTCLYPTATYFLMGTS
                     KGCVLIFNYNEHLQTILVPTLSEDPSIHSIRSPVKSIVICSDGTHVAASYETGNICIW
                     NLNVGYRVKPTSEPTNGMTPTPALPAVLHIDDHVNKEITGLDFFGARHTALIVSDRTG
                     KVSLYNGYRRGFWQLVYNSKKILDVNSSKEKLIRSKLSPLISREKISTNLLSVLTTTH
                     FALILLSPHVSLMFQETVEPSVQNSLVVNSSISWTQNCSRVAYSVNNKISVISISSSD
                     FNVQSASHSPEFAESILSIQWIDQLLLGVLTISHQFLVLHPQHDFKILLRLDFLIHDL
                     MIPPNKYFVISRRSFYLLTNYSFKIGKFVSWSDITLRHILKGDYLGALEFIESLLQPY
                     CPLANLLKLDNNTEERTKQLMEPFYNLSLAALRFLIKKDNADYNRVYQLLMVVVRVLQ
                     QSSKKLDSIPSLDVFLEQGLEFFELKDNAVYFEVVANIVAQGSVTSISPVLFRSIIDY
                     YAKEENLKVIEDLIIMLNPTTLDVDLAVKLCQKYNLFDLLIYIWNKIFDDYQTPVVDL
                     IYRISNQSEKCVIFNGPQVPPETTIFDYVTYILTGRQYPQNLSISPSDKCSKIQRELS
                     AFIFSGFSIKWPSNSNHKLYICENPEEEPAFPYFHLLLKSNPSRFLAMLNEVFEASLF
                     NDDNDMVASVGEAELVSRQYVIDLLLDAMKDTGNSDNIRVLVAIFIATSISKYPQFIK
                     VSNQALDCVVNTICSSRVQGIYEISQIALESLLPYYHSRTTENFILELKEKNFNKVLF
                     HIYKSENKYASALSLILETKDIEKEYNTDIVSITDYILKKCPPGSLECGKVTEVIETN
                     FDLLLSRIGIEKCVTIFSDFDYNLHQEILEVKNEETQQKYLDKLFSTPNINNKVDKRL
                     RNLHIELNCKYKSKREMILWLNGTVLSNAESLQILDLLNQDSNFEAAAIIHERLESFN
                     LAVRDLLSFIEQCLNEGKTNISTLLESLRRAFDDCNSAGTEKKSCWILLITFLITLYG
                     KYPSHDERKDLCNKLLQEAFLGLVRSKSSSQKDSGGEFWEIMSSVLEHQDVILMKVQD
                     LKQLLLNVFNTYKLERSLSELIQKIIEDSSQDLVQQYRKFLSEGWSIHTDDCEICGKK
                     IWGAGLDPLLFLAWENVQRHQDMISVDLKTPLVIFKCHHGFHQTCLENLAQKPDEYSC
                     LICQTESNPKIV"
     rep_origin      147398..147717
                     /note="ARS108;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121255"
     gene            complement(<147594..>151166)
                     /gene="TFC3"
                     /locus_tag="YAL001C"
                     /gene_synonym="FUN24; TSV115"
                     /db_xref="GeneID:851262"
     mRNA            complement(join(<147594..151006,151097..>151166))
                     /gene="TFC3"
                     /locus_tag="YAL001C"
                     /gene_synonym="FUN24; TSV115"
                     /product="transcription factor TFIIIC subunit TFC3"
                     /transcript_id="NM_001178148.1"
                     /db_xref="GeneID:851262"
     CDS             complement(join(147594..151006,151097..151166))
                     /gene="TFC3"
                     /locus_tag="YAL001C"
                     /gene_synonym="FUN24; TSV115"
                     /note="Subunit of RNA polymerase III transcription
                     initiation factor complex; part of the TauB domain of
                     TFIIIC that binds DNA at the BoxB promoter sites of tRNA
                     and similar genes; cooperates with Tfc6p in DNA binding;
                     largest of six subunits of the RNA polymerase III
                     transcription initiation factor complex (TFIIIC)"
                     /codon_start=1
                     /product="transcription factor TFIIIC subunit TFC3"
                     /protein_id="NP_009400.1"
                     /db_xref="GeneID:851262"
                     /db_xref="SGD:S000000001"
                     /translation="MVLTIYPDELVQIVSDKIASNKGKITLNQLWDISGKYFDLSDKK
                     VKQFVLSCVILKKDIEVYCDGAITTKNVTDIIGDANHSYSVGITEDSLWTLLTGYTKK
                     ESTIGNSAFELLLEVAKSGEKGINTMDLAQVTGQDPRSVTGRIKKINHLLTSSQLIYK
                     GHVVKQLKLKKFSHDGVDSNPYINIRDHLATIVEVVKRSKNGIRQIIDLKRELKFDKE
                     KRLSKAFIAAIAWLDEKEYLKKVLVVSPKNPAIKIRCVKYVKDIPDSKGSPSFEYDSN
                     SADEDSVSDSKAAFEDEDLVEGLDNFNATDLLQNQGLVMEEKEDAVKNEVLLNRFYPL
                     QNQTYDIADKSGLKGISTMDVVNRITGKEFQRAFTKSSEYYLESVDKQKENTGGYRLF
                     RIYDFEGKKKFFRLFTAQNFQKLTNAEDEISVPKGFDELGKSRTDLKTLNEDNFVALN
                     NTVRFTTDSDGQDIFFWHGELKIPPNSKKTPNKNKRKRQVKNSTNASVAGNISNPKRI
                     KLEQHVSTAQEPKSAEDSPSSNGGTVVKGKVVNFGGFSARSLRSLQRQRAILKVMNTI
                     GGVAYLREQFYESVSKYMGSTTTLDKKTVRGDVDLMVESEKLGARTEPVSGRKIIFLP
                     TVGEDAIQRYILKEKDSKKATFTDVIHDTEIYFFDQTEKNRFHRGKKSVERIRKFQNR
                     QKNAKIKASDDAISKKSTSVNVSDGKIKRRDKKVSAGRTTVVVENTKEDKTVYHAGTK
                     DGVQALIRAVVVTKSIKNEIMWDKITKLFPNNSLDNLKKKWTARRVRMGHSGWRAYVD
                     KWKKMLVLAIKSEKISLRDVEELDLIKLLDIWTSFDEKEIKRPLFLYKNYEENRKKFT
                     LVRDDTLTHSGNDLAMSSMIQREISSLKKTYTRKISASTKDLSKSQSDDYIRTVIRSI
                     LIESPSTTRNEIEALKNVGNESIDNVIMDMAKEKQIYLHGSKLECTDTLPDILENRGN
                     YKDFGVAFQYRCKVNELLEAGNAIVINQEPSDISSWVLIDLISGELLNMDVIPMVRNV
                     RPLTYTSRRFEIRTLTPPLIIYANSQTKLNTARKSAVKVPLGKPFSRLWVNGSGSIRP
                     NIWKQVVTMVVNEIIFHPGITLSRLQSRCREVLSLHEISEICKWLLERQVLITTDFDG
                     YWVNHNWYSIYEST"
     centromere      151465..151582
                     /note="CEN1; Chromosome I centromere"
                     /db_xref="SGD:S000006463"
     centromere      151465..151474
                     /note="CEN1_CDEI of CEN1"
     centromere      151475..151557
                     /note="CEN1_CDEII of CEN1"
     centromere      151558..151582
                     /note="CEN1_CDEIII of CEN1"
     gene            <152257..>153876
                     /gene="NUP60"
                     /locus_tag="YAR002W"
                     /db_xref="GeneID:851263"
     mRNA            <152257..>153876
                     /gene="NUP60"
                     /locus_tag="YAR002W"
                     /product="FG-nucleoporin NUP60"
                     /transcript_id="NM_001178209.1"
                     /db_xref="GeneID:851263"
     CDS             152257..153876
                     /gene="NUP60"
                     /locus_tag="YAR002W"
                     /note="FG-nucleoporin component of central core of the
                     nuclear pore complex; contributes directly to
                     nucleocytoplasmic transport and maintenance of the nuclear
                     pore complex (NPC) permeability barrier and is involved in
                     gene tethering at the nuclear periphery; relocalizes to
                     the cytosol in response to hypoxia; both NUP1 and NUP60
                     are homologous to human NUP153"
                     /codon_start=1
                     /product="FG-nucleoporin NUP60"
                     /protein_id="NP_009401.1"
                     /db_xref="GeneID:851263"
                     /db_xref="SGD:S000000063"
                     /translation="MHRKSLRRASATVPSAPYRKQIISNAHNKPSLFSKIKTFFTQKD
                     SARVSPRNNVANKQPRNESFNRRISSMPGGYFHSEISPDSTVNRSVVVSAVGEARNDI
                     ENKEEEYDETHETNISNAKLANFFSKKGNEPLSEIEIEGVMSLLQKSSKSMITSEGEQ
                     KSAEGNNIDQSLILKESGSTPISISNAPTFNPKYDTSNASMNTTLGSIGSRKYSFNYS
                     SLPSPYKTTVYRYSAAKKIPDTYTANTSAQSIASAKSVRSGVSKSAPSKKISNTAAAL
                     VSLLDENDSKKNNAASELANPYSSYVSQIRKHKRVSPNAAPRQEISEEETTVKPLFQN
                     VPEQGEEPMKQLNATKISPSAPSKDSFTKYKPARSSSLRSNVVVAETSPEKKDGGDKP
                     PSSAFNFSFNTSRNVEPTENAYKSENAPSASSKEFNFTNLQAKPLVGKPKTELTKGDS
                     TPVQPDLSVTPQKSSSKGFVFNSVQKKSRSNLSQENDNEGKHISASIDNDFSEEKAEE
                     FDFNVPVVSKQLGNGLVDENKVEAFKSLYTF"
     gene            complement(<154065..>154724)
                     /gene="ERP1"
                     /locus_tag="YAR002C-A"
                     /db_xref="GeneID:851264"
     mRNA            complement(<154065..>154724)
                     /gene="ERP1"
                     /locus_tag="YAR002C-A"
                     /product="Erp1p"
                     /transcript_id="NM_001180033.1"
                     /db_xref="GeneID:851264"
     CDS             complement(154065..154724)
                     /gene="ERP1"
                     /locus_tag="YAR002C-A"
                     /note="Member of the p24 family involved in ER to Golgi
                     transport; role in misfolded protein quality control;
                     forms heterotrimeric complex with Erp2p, Emp24p, and
                     Erv25p; localized to COPII-coated vesicles; ERP1 has a
                     paralog, ERP6, that arose from the whole genome
                     duplication"
                     /codon_start=1
                     /product="Erp1p"
                     /protein_id="NP_009402.1"
                     /db_xref="GeneID:851264"
                     /db_xref="SGD:S000002129"
                     /translation="MLLTSLLQVFACCLVLPAQVTAFYYYTSGAERKCFHKELSKGTL
                     FQATYKAQIYDDQLQNYRDAGAQDFGVLIDIEETFDDNHLVVHQKGSASGDLTFLASD
                     SGEHKICIQPEAGGWLIKAKTKIDVEFQVGSDEKLDSKGKATIDILHAKVNVLNSKIG
                     EIRREQKLMRDREATFRDASEAVNSRAMWWIVIQLIVLAVTCGWQMKHLGKFFVKQKI
                     L"
     gene            <155005..>156285
                     /gene="SWD1"
                     /locus_tag="YAR003W"
                     /gene_synonym="CPS50; FUN16; SAF49"
                     /db_xref="GeneID:851265"
     mRNA            <155005..>156285
                     /gene="SWD1"
                     /locus_tag="YAR003W"
                     /gene_synonym="CPS50; FUN16; SAF49"
                     /product="COMPASS subunit protein SWD1"
                     /transcript_id="NM_001178210.1"
                     /db_xref="GeneID:851265"
     CDS             155005..156285
                     /gene="SWD1"
                     /locus_tag="YAR003W"
                     /gene_synonym="CPS50; FUN16; SAF49"
                     /note="Subunit of the COMPASS (Set1C) complex; COMPASS
                     methylates histone H3 on lysine 4 and is required in
                     transcriptional silencing near telomeres; WD40 beta
                     propeller superfamily member with similarity to mammalian
                     Rbbp7"
                     /codon_start=1
                     /product="COMPASS subunit protein SWD1"
                     /protein_id="NP_009403.1"
                     /db_xref="GeneID:851265"
                     /db_xref="SGD:S000000064"
                     /translation="MNILLQDPFAVLKEHPEKLTHTIENPLRTECLQFSPCGDYLALG
                     CANGALVIYDMDTFRPICVPGNMLGAHVRPITSIAWSPDGRLLLTSSRDWSIKLWDLS
                     KPSKPLKEIRFDSPIWGCQWLDAKRRLCVATIFEESDAYVIDFSNDPVASLLSKSDEK
                     QLSSTPDHGYVLVCTVHTKHPNIIIVGTSKGWLDFYKFHSLYQTECIHSLKITSSNIK
                     HLIVSQNGERLAINCSDRTIRQYEISIDDENSAVELTLEHKYQDVINKLQWNCILFSN
                     NTAEYLVASTHGSSAHELYIWETTSGTLVRVLEGAEEELIDINWDFYSMSIVSNGFES
                     GNVYVWSVVIPPKWSALAPDFEEVEENVDYLEKEDEFDEVDEAEQQQGLEQEEEIAID
                     LRTREQYDVRGNNLLVERFTIPTDYTRIIKMQSS"
     gene            complement(<156754..>158619)
                     /gene="RFA1"
                     /locus_tag="YAR007C"
                     /gene_synonym="BUF2; FUN3; RPA1; RPA70"
                     /db_xref="GeneID:851266"
     mRNA            complement(<156754..>158619)
                     /gene="RFA1"
                     /locus_tag="YAR007C"
                     /gene_synonym="BUF2; FUN3; RPA1; RPA70"
                     /product="replication factor A subunit protein RFA1"
                     /transcript_id="NM_001178211.1"
                     /db_xref="GeneID:851266"
     CDS             complement(156754..158619)
                     /gene="RFA1"
                     /locus_tag="YAR007C"
                     /gene_synonym="BUF2; FUN3; RPA1; RPA70"
                     /note="Subunit of heterotrimeric Replication Protein A
                     (RPA); RPA is a highly conserved single-stranded DNA
                     binding protein involved in DNA replication, repair, and
                     recombination; RPA protects against inappropriate telomere
                     recombination, and upon telomere uncapping, prevents cell
                     proliferation by a checkpoint-independent pathway; role in
                     DNA catenation/decatenation pathway of chromosome
                     disentangling; relocalizes to the cytosol in response to
                     hypoxia"
                     /codon_start=1
                     /product="replication factor A subunit protein RFA1"
                     /protein_id="NP_009404.1"
                     /db_xref="GeneID:851266"
                     /db_xref="SGD:S000000065"
                     /translation="MSSVQLSRGDFHSIFTNKQRYDNPTGGVYQVYNTRKSDGANSNR
                     KNLIMISDGIYHMKALLRNQAASKFQSMELQRGDIIRVIIAEPAIVRERKKYVLLVDD
                     FELVQSRADMVNQTSTFLDNYFSEHPNETLKDEDITDSGNVANQTNASNAGVPDMLHS
                     NSNLNANERKFANENPNSQKTRPIFAIEQLSPYQNVWTIKARVSYKGEIKTWHNQRGD
                     GKLFNVNFLDTSGEIRATAFNDFATKFNEILQEGKVYYVSKAKLQPAKPQFTNLTHPY
                     ELNLDRDTVIEECFDESNVPKTHFNFIKLDAIQNQEVNSNVDVLGIIQTINPHFELTS
                     RAGKKFDRRDITIVDDSGFSISVGLWNQQALDFNLPEGSVAAIKGVRVTDFGGKSLSM
                     GFSSTLIPNPEIPEAYALKGWYDSKGRNANFITLKQEPGMGGQSAASLTKFIAQRITI
                     ARAQAENLGRSEKGDFFSVKAAISFLKVDNFAYPACSNENCNKKVLEQPDGTWRCEKC
                     DTNNARPNWRYILTISIIDETNQLWLTLFDDQAKQLLGVDANTLMSLKEEDPNEFTKI
                     TQSIQMNEYDFRIRAREDTYNDQSRIRYTVANLHSLNYRAEADYLADELSKALLA"
     gene            <158966..>159793
                     /gene="SEN34"
                     /locus_tag="YAR008W"
                     /gene_synonym="FUN4"
                     /db_xref="GeneID:851267"
     mRNA            <158966..>159793
                     /gene="SEN34"
                     /locus_tag="YAR008W"
                     /gene_synonym="FUN4"
                     /product="tRNA splicing endonuclease subunit SEN34"
                     /transcript_id="NM_001178212.1"
                     /db_xref="GeneID:851267"
     CDS             158966..159793
                     /gene="SEN34"
                     /locus_tag="YAR008W"
                     /gene_synonym="FUN4"
                     /EC_number="4.6.1.16"
                     /note="Subunit of the tRNA splicing endonuclease; tRNA
                     splicing endonuclease (Sen complex) is composed of Sen2p,
                     Sen15p, Sen34p, and Sen54p; Sen complex also cleaves the
                     CBP1 mRNA at the mitochondrial surface; Sen34p contains
                     the active site for tRNA 3' splice site cleavage and has
                     similarity to Sen2p and to Archaeal tRNA splicing
                     endonuclease"
                     /codon_start=1
                     /product="tRNA splicing endonuclease subunit SEN34"
                     /protein_id="NP_009405.1"
                     /db_xref="GeneID:851267"
                     /db_xref="SGD:S000000066"
                     /translation="MPPLVFDIDHIKLLRKWGICGVLSGTLPTAAQQNVFLSVPLRLM
                     LEDVLWLHLNNLADVKLIRQEGDEIMEGITLERGAKLSKIVNDRLNKSFEYQRKFKKD
                     EHIAKLKKIGRINDKTTAEELQRLDKSSNNDQLIESSLFIDIANTSMILRDIRSDSDS
                     LSRDDISDLLFKQYRQAGKMQTYFLYKALRDQGYVLSPGGRFGGKFIAYPGDPLRFHS
                     HLTIQDAIDYHNEPIDLISMISGARLGTTVKKLWVIGGVAEETKETHFFSIEWAGFG"
     rep_origin      159907..160127
                     /note="ARS101;
                     ARS containing multiple redundant ORC binding sites; ORC
                     is the acronym for origin recognition complex"
                     /db_xref="SGD:S000077372"
     repeat_region   complement(160105..160237)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006788"
     mobile_element  complement(160238..166162)
                     /note="YARCTy1-1; Ty1 element, LTR retrotransposon of the
                     Copia (Pseudoviridae) group; contains genes TYA Gag and
                     TYB Pol, encoding proteins involved in structure and
                     function of virus-like particles, flanked by two direct
                     repeats; mutated in S288C"
                     /mobile_element_type="retrotransposon:YARCTy1-1"
                     /db_xref="SGD:S000006792"
     repeat_region   complement(160238..160574)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006789"
     gene            complement(<160597..>164187)
                     /locus_tag="YAR009C"
                     /db_xref="GeneID:851268"
     mRNA            complement(<160597..>164187)
                     /locus_tag="YAR009C"
                     /product="truncated gag-pol fusion protein"
                     /transcript_id="NM_001178213.1"
                     /db_xref="GeneID:851268"
     CDS             complement(160597..164187)
                     /locus_tag="YAR009C"
                     /EC_number="3.1.26.4"
                     /EC_number="2.7.7.7"
                     /EC_number="2.7.7.49"
                     /note="Retrotransposon TYA Gag and TYB Pol genes; Gag
                     processing produces capsid proteins, Pol is cleaved to
                     produce protease, reverse transcriptase and integrase
                     activities; in YARCTy1-1 TYB is mutant and probably
                     non-functional; protein product forms cytoplasmic foci
                     upon DNA replication stress"
                     /codon_start=1
                     /product="truncated gag-pol fusion protein"
                     /protein_id="NP_009406.1"
                     /db_xref="GeneID:851268"
                     /db_xref="SGD:S000000067"
                     /translation="METFTGYLKSTCFHQISPYPPSIMSIQVKVHANILILSFIECLR
                     MPMHRQIRYSLKNNTITYFNESDVDWSSAIDYQCPDCLIGKSTKHRHIKGSRLKYQNS
                     YEPFQYLHTDIFGPVHNLPKSAPSYFISFTDETTKLRWVYPLHDRREDSILDVFTTIL
                     AFIKNQFQASVLVIQMDRGSEYTNRTLHKFLEKNGITPCYTTTADSRAHGVAERLNRT
                     LLDDCRTQLQCSGLPNHLWFSAIEFSTIVRNSLASPKSKKSARQHAGLAGLDISTLLP
                     FGQPVIVNDHNPNSKIHPRGIPGYALHPSRNSYGYIIYLPSLKKTVDTTNYVILQGKE
                     SRLDQFNYDALTFDEDLNRLTASYHSFIASNEIQESNDLNIESDHDFQSDIELHPEQP
                     RNVLSKAVSPTDSTPPSTHTEDSKRVSKTNIRAPREVDPNISESNILPSKKRSSTPQI
                     SNIESTGSGGMHKLNVPLLAPMSQSNTHESSHASKSKDFRHSDSYSENETNHTNVPIS
                     STGGTNNKTVPQISDQETEKRIIHRSPSIDASPPENNSSHNIVPIKTPTTVSEQNTEE
                     SIIADLPLPDLPPESPTEFPDPFKELPPINSHQTNSSLGGIGDSNAYTTINSKKRSLE
                     DNETEIKVSRDTWNTKNMRSLEPPRSKKRIHLIAAVKAVKSIKPIRTTLRYDEAITYN
                     KDIKEKEKYIEAYHKEVNQLLKMNTWDTDKYYDRKEIDPKRVINSMFIFNKKRDGTHK
                     ARFVARGDIQHPDTYDTGMQSNTVHHYALMTSLSLALDNNYYITQLDISSAYLYADIK
                     EELYIRPPPHLGMNDKLIRLKKSLYGLKQSGANWYETIKSYLIKQCGMEEVRGWSCVF
                     KNSQVTICLFVDDMILFSKDLNANKKIITTLKKQYDTKIINLGESDNEIQYDILGLEI
                     KYQRGKYMKLGMEKSLTEKLPKLNVPLNPKGKKLRAPGQPGLYIDQDELEIDEDEYKE
                     KVHEMQKLIGLASYVGYKFRFDLLYYINTLAQHILFPSRQVLDMTYELIQFMWDTRDK
                     QLIWHKNKPTEPDNKLVAISDASYGNQPYYKSQIGNIYLLNGKVIGGKSTKASLTCTS
                     TTEAEIHAISESVPLLNNLSYLIQELNKKPIIKGLLTDSRSTISIIKSTNEEKFRNRF
                     FGTKAMRLRDEVSGNNLYVYYIETKKNIADVMTKPLPIKTFKLLTNKWIH"
     gene            complement(<164544..>165866)
                     /locus_tag="YAR010C"
                     /db_xref="GeneID:851269"
     mRNA            complement(<164544..>165866)
                     /locus_tag="YAR010C"
                     /product="gag protein"
                     /transcript_id="NM_001178214.1"
                     /db_xref="GeneID:851269"
     CDS             complement(164544..165866)
                     /locus_tag="YAR010C"
                     /note="Retrotransposon TYA Gag gene co-transcribed with
                     TYB Pol; Gag processing produces capsid proteins; in
                     YARCTy1-1 TYB is mutant and probably non-functional"
                     /codon_start=1
                     /product="gag protein"
                     /protein_id="NP_009407.1"
                     /db_xref="GeneID:851269"
                     /db_xref="SGD:S000000068"
                     /translation="MESQQLSQHSPISHGSACASVTSKEVHTNQDPLDVSASKTEECE
                     KASTKANSQQTTTPASSAVPENPHHASPQTAQSHSPQNGPYPQQCMMTQNQANPSGWS
                     FYGHPSMIPYTPYQMSPMYFPPGPQSQFPQYPSSVGTPLSTPSPESGNTFTDSSSADS
                     DMTSTKKYVRPPPMLTSPNDFPNWVKTYIKFLQNSNLGGIIPTVNGKPVRQITDDELT
                     FLYNTFQIFAPSQFLPTWVKDILSVDYTDIMKILSKSIEKMQSDTQEANDIVTLANLQ
                     YNGSTPADAFETKVTNIIDRLNNNGIHINNKVACQLIMRGLSGEYKFLRYTRHRHLNM
                     TVAELFLDIHAIYEEQQGSRNSKPNYRRNPSDEKNDSRSYTNTTKPKVIARNPQKTNN
                     SKSKTARAHNVSTSNNSPSTDNDSISKSTTEPIQLNNKHDLHLRPETY"
     repeat_region   complement(165826..166162)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006790"
     gene            166267..166339
                     /gene="TGA1"
                     /locus_tag="tA(UGC)A"
                     /db_xref="GeneID:851270"
     tRNA            166267..166339
                     /gene="TGA1"
                     /locus_tag="tA(UGC)A"
                     /product="tRNA-Ala"
                     /note="Alanine tRNA (tRNA-Ala), predicted by tRNAscan-SE
                     analysis; one of 5 nuclear tRNA genes containing the
                     tDNA-anticodon TGC (mature tRNA may be UGC or may contain
                     modified bases), decodes GCA and probably GCG codons into
                     alanine, one of 16 nuclear tRNAs for alanine"
                     /db_xref="GeneID:851270"
                     /db_xref="SGD:S000006521"
     gene            complement(<166742..>168871)
                     /gene="BUD14"
                     /locus_tag="YAR014C"
                     /db_xref="GeneID:851271"
     mRNA            complement(<166742..>168871)
                     /gene="BUD14"
                     /locus_tag="YAR014C"
                     /product="protein phosphatase regulator BUD14"
                     /transcript_id="NM_001178215.2"
                     /db_xref="GeneID:851271"
     CDS             complement(166742..168871)
                     /gene="BUD14"
                     /locus_tag="YAR014C"
                     /note="Protein involved in bud-site selection;
                     Bud14p-Glc7p complex is a cortical regulator of dynein;
                     forms a complex with Kel1p and Kel2p that regulates Bnr1p
                     (formin) to affect actin cable assembly, cytokinesis, and
                     polarized growth; diploid mutants display a random budding
                     pattern instead of the wild-type bipolar pattern; relative
                     distribution to the nucleus increases upon DNA replication
                     stress"
                     /codon_start=1
                     /product="protein phosphatase regulator BUD14"
                     /protein_id="NP_009408.3"
                     /db_xref="GeneID:851271"
                     /db_xref="SGD:S000000069"
                     /translation="MSNKEEHVDETSASGVKEVSSIAARHDNGYAPSLITSTSGMDSF
                     QSHALLNDPTLIEDYSDIINNRPTSGSKLTLGNEDSESMGGSVVVTPTSNKSSPFNSK
                     LNILSNAAEKGHDVLRNRDDDKELEEENVEKHMHSNSKRDQRHYKENSSELPDSYDYS
                     DSEFEDNLERRLQEIETDSVDSADKDEVHFSVNNTMNPDVDDFSDGLKYAISEDEDEE
                     ENYSDDDDFDRKFQDSGFQGEKDDLEEENDDYQPLSPPRELDPDKLYALYAFNGHDSS
                     HCQLGQDEPCILLNDQDAYWWLVKRITDGKIGFAPAEILETFPERLARLNCWKNENMS
                     SQSVASSDSKDDSISSGNKNQSDAESIIPTPALNGYGKGNKSVSFNDVVGYADRFIDD
                     AIEDTSLDSNDDGGEGNGQSYDDDVDNDKETKVTHRDEYTEAKLNFGKFQDDDTSDVV
                     SDVSFSTSLNTPLNVKKVRRQDNKNESEPKTSSSKDREDDYNANRYVGQEKSEPVDSD
                     YDTDLKKVFEAPRMPFANGMAKSDSQNSLSTIGEFSPSSSEWTNESPSTPIVEESSSI
                     PSSRAIKDISQYIHAKSKIEETTNVENTEGQIQASLGSSGGMANQTDAEQPKEELEKH
                     HSTPEEEKQSTLSLHSSSEEDFYMDEQRAVSSASINSSLSGSRALSNTNMSDPASKPN
                     SLVQHLYAPVFDRMDVLMKQLDEIIRK"
     gene            <169375..>170295
                     /gene="ADE1"
                     /locus_tag="YAR015W"
                     /db_xref="GeneID:851272"
     mRNA            <169375..>170295
                     /gene="ADE1"
                     /locus_tag="YAR015W"
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /transcript_id="NM_001178216.1"
                     /db_xref="GeneID:851272"
     CDS             169375..170295
                     /gene="ADE1"
                     /locus_tag="YAR015W"
                     /EC_number="6.3.2.6"
                     /note="N-succinyl-5-aminoimidazole-4-carboxamide ribotide
                     synthetase; required for 'de novo' purine nucleotide
                     biosynthesis; red pigment accumulates in mutant cells
                     deprived of adenine; protein abundance increases in
                     response to DNA replication stress"
                     /codon_start=1
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="NP_009409.1"
                     /db_xref="GeneID:851272"
                     /db_xref="SGD:S000000070"
                     /translation="MSITKTELDGILPLVARGKVRDIYEVDAGTLLFVATDRISAYDV
                     IMENSIPEKGILLTKLSEFWFKFLSNDVRNHLVDIAPGKTIFDYLPAKLSEPKYKTQL
                     EDRSLLVHKHKLIPLEVIVRGYITGSAWKEYVKTGTVHGLKQPQGLKESQEFPEPIFT
                     PSTKAEQGEHDENISPAQAAELVGEDLSRRVAELAVKLYSKCKDYAKEKGIIIADTKF
                     EFGIDEKTNEIILVDEVLTPDSSRFWNGASYKVGESQDSYDKQFLRDWLTANKLNGVN
                     GVKMPQDIVDRTRAKYIEAYETLTGSKWSH"
     gene            complement(<170396..>171703)
                     /gene="KIN3"
                     /locus_tag="YAR018C"
                     /gene_synonym="FUN52; NPK1"
                     /db_xref="GeneID:851273"
     mRNA            complement(<170396..>171703)
                     /gene="KIN3"
                     /locus_tag="YAR018C"
                     /gene_synonym="FUN52; NPK1"
                     /product="serine/threonine protein kinase KIN3"
                     /transcript_id="NM_001178217.1"
                     /db_xref="GeneID:851273"
     CDS             complement(170396..171703)
                     /gene="KIN3"
                     /locus_tag="YAR018C"
                     /gene_synonym="FUN52; NPK1"
                     /EC_number="2.7.11.1"
                     /note="Nonessential serine/threonine protein kinase;
                     possible role in DNA damage response; influences tolerance
                     to high levels of ethanol"
                     /codon_start=1
                     /product="serine/threonine protein kinase KIN3"
                     /protein_id="NP_009410.1"
                     /db_xref="GeneID:851273"
                     /db_xref="SGD:S000000071"
                     /translation="MHRRQFFQEYRSPQQQQGHPPRSEYQVLEEIGRGSFGSVRKVIH
                     IPTKKLLVRKDIKYGHMNSKERQQLIAECSILSQLKHENIVEFYNWDFDEQKEVLYLY
                     MEYCSRGDLSQMIKHYKQEHKYIPEKIVWGILAQLLTALYKCHYGVELPTLTTIYDRM
                     KPPVKGKNIVIHRDLKPGNIFLSYDDSDYNINEQVDGHEEVNSNYYRDHRVNSGKRGS
                     PMDYSQVVVKLGDFGLAKSLETSIQFATTYVGTPYYMSPEVLMDQPYSPLSDIWSLGC
                     VIFEMCSLHPPFQAKNYLELQTKIKNGKCDTVPEYYSRGLNAIIHSMIDVNLRTRPST
                     FELLQDIQIRTARKSLQLERFERKLLDYENELTNIEKILEKQAIEYERELSQLKEQFT
                     QAVEERAREVISGKKVGKVPESINGYYGKKFAKPAYHWQTRYR"
     gene            complement(<172211..>175135)
                     /gene="CDC15"
                     /locus_tag="YAR019C"
                     /gene_synonym="LYT1"
                     /db_xref="GeneID:851274"
     mRNA            complement(<172211..>175135)
                     /gene="CDC15"
                     /locus_tag="YAR019C"
                     /gene_synonym="LYT1"
                     /product="serine/threonine protein kinase CDC15"
                     /transcript_id="NM_001178218.2"
                     /db_xref="GeneID:851274"
     CDS             complement(172211..175135)
                     /gene="CDC15"
                     /locus_tag="YAR019C"
                     /gene_synonym="LYT1"
                     /EC_number="2.7.11.1"
                     /note="Protein kinase of the Mitotic Exit Network;
                     localized to the spindle pole bodies at late anaphase;
                     promotes mitotic exit by directly switching on the kinase
                     activity of Dbf2p; required for spindle disassembly after
                     meiosis II; relocalizes to the cytoplasm upon DNA
                     replication stress"
                     /codon_start=1
                     /product="serine/threonine protein kinase CDC15"
                     /protein_id="NP_009411.2"
                     /db_xref="GeneID:851274"
                     /db_xref="SGD:S000000072"
                     /translation="MNSMADTDRVNLTPIQRASEKSVQYHLKQVIGRGSYGVVYKAIN
                     KHTDQVVAIKEVVYENDEELNDIMAEISLLKNLNHNNIVKYHGFIRKSYELYILLEYC
                     ANGSLRRLISRSSTGLSENESKTYVTQTLLGLKYLHGEGVIHRDIKAANILLSADNTV
                     KLADFGVSTIVNSSALTLAGTLNWMAPEILGNRGASTLSDIWSLGATVVEMLTKNPPY
                     HNLTDANIYYAVENDTYYPPSSFSEPLKDFLSKCFVKNMYKRPTADQLLKHVWINSTE
                     NVKVDKLNKFKEDFTDADYHWDADFQEEKLNISPSKFSLAAAPAAWAENNQELDLMPP
                     TESQLLSQLKSSSKPLTDLHVLFSVCSLENIADTIIECLSRTTVDKRLITAFGSIFVY
                     DTQHNHSRLRLKFIAMGGIPLIIKFEHLAKEFVIDYPQTLIECGIMYPPNFASLKTPK
                     YILELVYRFYDLTSTAFWCRWCFKHLDISLLLNNIHERRAQSILLKLSSYAPWSFEKI
                     LPSLIDSKLKKKILISPQITYVVFKSINYMITTNDDKIHKSAIPSSSSLPLSSSPTRN
                     SPVNSVQSPSRSPVHSLMATRPSSPMRHKSISNFPHLTISSKSRLLIELPEGFFTWLT
                     SFFVDMAQIKDLSVLKYFTKLCYLTVHINSTFLNDLLDNDAFFAFIRNIDTIIPFIDD
                     AKTAAFIWKQITAICVEMSLDMDQMSASLFSTAMNFIRKKNNTSISGLEIILNCLHFT
                     LRNVNDDVAPTVGSSESHSVFLIKVNNDAAIELPIDQLVDLFYALNDDDVNLSKLISI
                     FTKICSLPGFENLTINIIFHPNFYEKIVSFFDTYFNSLLIQIDLLKFIKLIFSKSLLK
                     LYDYTGQPDPIKQTEPNRRNKATVFKLRAILVQITEFLNNNWNKDVPKRNSNQVGGDS
                     VLICQLCEDIRSLSKKGSLQKVSSVTAAIGSSPTKDERSNLRSSKDKSDGFSVPITTF
                     QT"
     rep_origin      176157..176404
                     /note="ARS110;
                     Autonomously Replicating Sequence; originally referred to
                     as ADE1 ARS"
                     /db_xref="SGD:S000114488"
     gene            complement(<176856..>177023)
                     /gene="PAU7"
                     /locus_tag="YAR020C"
                     /db_xref="GeneID:851275"
     mRNA            complement(<176856..>177023)
                     /gene="PAU7"
                     /locus_tag="YAR020C"
                     /product="seripauperin PAU7"
                     /transcript_id="NM_001178219.1"
                     /db_xref="GeneID:851275"
     CDS             complement(176856..177023)
                     /gene="PAU7"
                     /locus_tag="YAR020C"
                     /note="Member of the seripauperin multigene family; active
                     during alcoholic fermentation, regulated by anaerobiosis,
                     inhibited by oxygen, repressed by heme"
                     /codon_start=1
                     /product="seripauperin PAU7"
                     /protein_id="NP_009412.1"
                     /db_xref="GeneID:851275"
                     /db_xref="SGD:S000000073"
                     /translation="MVKLTSIAAGVAAIAAGASAAATTTLSQSDERVNLVELGVYVSD
                     IRAHLAEYYSF"
     gene            complement(<179281..>179820)
                     /locus_tag="YAR023C"
                     /db_xref="GeneID:851276"
     mRNA            complement(<179281..>179820)
                     /locus_tag="YAR023C"
                     /product="DUP240 family protein"
                     /transcript_id="NM_001178220.2"
                     /db_xref="GeneID:851276"
     CDS             complement(179281..179820)
                     /locus_tag="YAR023C"
                     /note="Putative integral membrane protein; member of
                     DUP240 gene family"
                     /codon_start=1
                     /product="DUP240 family protein"
                     /protein_id="NP_009413.2"
                     /db_xref="GeneID:851276"
                     /db_xref="SGD:S000000074"
                     /translation="MINFLLFVLTILATLTNIWFSGVLSPAMVIRICLGGSMVVLQIW
                     SFSRPISNETFRTKLLLEVITHRPSIAGKEWKTITYNMNQYLFKAGLWKTPYHFFCEH
                     QCYEFFKDLIKGKYPDVQWDTANTQPFISVPENQAATQNSDVEPTVKWCLFKAAEIQA
                     HAVREYWQSQYPDVGIPAI"
     gene            181141..181254
                     /gene="SUP56"
                     /locus_tag="tL(CAA)A"
                     /db_xref="GeneID:851277"
     tRNA            join(181141..181178,181211..181254)
                     /gene="SUP56"
                     /locus_tag="tL(CAA)A"
                     /product="tRNA-Leu"
                     /note="Leucine tRNA (tRNA-Leu), predicted by tRNAscan-SE
                     analysis; can mutate to suppress amber nonsense mutations"
                     /db_xref="GeneID:851277"
                     /db_xref="SGD:S000006636"
     gene            complement(182522..182603)
                     /locus_tag="tS(AGA)A"
                     /db_xref="GeneID:851278"
     tRNA            complement(182522..182603)
                     /locus_tag="tS(AGA)A"
                     /product="tRNA-Ser"
                     /note="Serine tRNA (tRNA-Ser), predicted by tRNAscan-SE
                     analysis"
                     /db_xref="GeneID:851278"
                     /db_xref="SGD:S000006719"
     repeat_region   182620..182959
                     /note="Ty3 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006795"
     repeat_region   183142..183474
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006793"
     gene            <183770..>184477
                     /gene="UIP3"
                     /locus_tag="YAR027W"
                     /db_xref="GeneID:851279"
     mRNA            <183770..>184477
                     /gene="UIP3"
                     /locus_tag="YAR027W"
                     /product="DUP240 family protein UIP3"
                     /transcript_id="NM_001178221.1"
                     /db_xref="GeneID:851279"
     CDS             183770..184477
                     /gene="UIP3"
                     /locus_tag="YAR027W"
                     /note="Putative integral membrane hypothetical protein;
                     interacts with Ulp1p at the nuclear periphery; member of
                     DUP240 gene family"
                     /codon_start=1
                     /product="DUP240 family protein UIP3"
                     /protein_id="NP_009414.1"
                     /db_xref="GeneID:851279"
                     /db_xref="SGD:S000000075"
                     /translation="MQTPSENTDVKLDTLDEPSAHLIEENVALPEDTFNSYWSYILNE
                     IARCKPLMIMFLIPVCLVLLITFFHDIKGILVFLVISLILSIIILLIGITAFVSETLN
                     KGFIIKLLVEVITRKPAVGGKEWRIIAYNMNQYLFDHGIWHTPYYFFCEHRCHKFFKS
                     LIKQTRSNAHLSSPTNGAENTQSNTPAKEVSNEMVKPYIFSSDPVLEAYLIKAAEIHK
                     EAEFEYWRKQYPEVDLP"
     gene            <184892..>185596
                     /locus_tag="YAR028W"
                     /db_xref="GeneID:851280"
     mRNA            <184892..>185596
                     /locus_tag="YAR028W"
                     /product="DUP240 family protein"
                     /transcript_id="NM_001178222.1"
                     /db_xref="GeneID:851280"
     CDS             184892..185596
                     /locus_tag="YAR028W"
                     /note="Putative integral membrane protein; member of
                     DUP240 gene family; GFP-fusion protein is induced in
                     response to the DNA-damaging agent MMS"
                     /codon_start=1
                     /product="DUP240 family protein"
                     /protein_id="NP_009415.1"
                     /db_xref="GeneID:851280"
                     /db_xref="SGD:S000000076"
                     /translation="MQTPSENTDVKMDTLDEPSAHLIEENVALPEDTFSSHLSYVLYE
                     IAHCKPIMFMIIIIVSLISLIVLFHDNDGCTVILVMSLIVASMALMVVAAFTFGKAIT
                     EQEFMIKLLVEVIARKPAGKEWGTVAYNMNQYLFMKRLWYTPYYFYSGKKCHEFFTTL
                     IKEVNSGSHSDSSSNSAEDTQSPVSAGKTSNGLNNFYSIRSDPILMAYVLKATQIEKE
                     AQSEYWRKQYPDADLP"
     gene            <186321..>186545
                     /locus_tag="YAR029W"
                     /db_xref="GeneID:851281"
     mRNA            <186321..>186545
                     /locus_tag="YAR029W"
                     /product="DUP240 family protein"
                     /transcript_id="NM_001178223.1"
                     /db_xref="GeneID:851281"
     CDS             186321..186545
                     /locus_tag="YAR029W"
                     /note="Member of DUP240 gene family but contains no
                     transmembrane domains; green fluorescent protein
                     (GFP)-fusion protein localizes to the cytoplasm in a
                     punctate pattern"
                     /codon_start=1
                     /product="DUP240 family protein"
                     /protein_id="NP_009416.1"
                     /db_xref="GeneID:851281"
                     /db_xref="SGD:S000000077"
                     /translation="MNKYLFDHKIWSTPYYFYCEEDCHRLFLSFIEGRTFEKPTSNAE
                     ENVQETEAGESFTLNPGEDFQNCFPRQRIL"
     gene            <186836..>187732
                     /gene="PRM9"
                     /locus_tag="YAR031W"
                     /db_xref="GeneID:851282"
     mRNA            <186836..>187732
                     /gene="PRM9"
                     /locus_tag="YAR031W"
                     /product="pheromone-regulated DUP240 family protein PRM9"
                     /transcript_id="NM_001178224.1"
                     /db_xref="GeneID:851282"
     CDS             186836..187732
                     /gene="PRM9"
                     /locus_tag="YAR031W"
                     /note="Pheromone-regulated protein; contains 3 predicted
                     transmembrane segments and an FF sequence, a motif
                     involved in COPII binding; member of DUP240 gene family;
                     PRM9 has a paralog, PRM8, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="pheromone-regulated DUP240 family protein PRM9"
                     /protein_id="NP_009418.1"
                     /db_xref="GeneID:851282"
                     /db_xref="SGD:S000000078"
                     /translation="MSPQYHFYFVSFRNLVLNEKCLRSKKQVMKSFNWYKTDRYFDPH
                     NILQHHSRAIEKTRYKLGMQTSSESTDAKSDFLDEPSAYLIEKNVALPKDIFGSYLSY
                     WIYEVTRHKAAVILLVLIVTSILLLVFFYNTEFCVAFEILLFSFCFPGTCMVVIAFSE
                     PIGDREFKVKLLMEIITRKPAVKGKEWRTITYKMNQYLFDHGLWDTPYYFYRDEDCHR
                     YFLSLIKGRTFKKQKESSASNVKDAQSNDETAGTPNEAAESSSFSAGPNFIKLLTKAA
                     EIEQQFQKEYWRQEYPGVDEFF"
     gene            <188107..>188811
                     /gene="MST28"
                     /locus_tag="YAR033W"
                     /db_xref="GeneID:851284"
     mRNA            <188107..>188811
                     /gene="MST28"
                     /locus_tag="YAR033W"
                     /product="DUP240 family protein MST28"
                     /transcript_id="NM_001178225.1"
                     /db_xref="GeneID:851284"
     CDS             188107..188811
                     /gene="MST28"
                     /locus_tag="YAR033W"
                     /note="Putative integral membrane protein, involved in
                     vesicle formation; forms complex with Mst27p; member of
                     DUP240 gene family; binds COPI and COPII vesicles; MST28
                     has a paralog, MST27, that arose from a segmental
                     duplication"
                     /codon_start=1
                     /product="DUP240 family protein MST28"
                     /protein_id="NP_009419.1"
                     /db_xref="GeneID:851284"
                     /db_xref="SGD:S000000079"
                     /translation="MQTPPESTDVKLDTLNEPSAHLIEKNVALPKDIFRSYLSYWIYE
                     IARYTPVMILSLVIGVLVLLIIFFNDNEACVFNSAIFAFTSLVGLLIILSDGNPKLVS
                     RRNFRTELLVDVITRKPAVEGKEWRIITYNMNQYLFNHGQWHTPYYFYSDEDCYRYFL
                     RLVEGVTPKKQTATSIGNSPVTAKPEDAIESASPSSRLNYQNFLLKAAEIERQAQENY
                     WRRRHPNIDALLKKTE"
     repeat_region   189426..189757
                     /note="Ty2 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006794"
     gene            <190193..>192256
                     /gene="YAT1"
                     /locus_tag="YAR035W"
                     /db_xref="GeneID:851285"
     mRNA            <190193..>192256
                     /gene="YAT1"
                     /locus_tag="YAR035W"
                     /product="carnitine O-acetyltransferase YAT1"
                     /transcript_id="NM_001178226.1"
                     /db_xref="GeneID:851285"
     CDS             190193..192256
                     /gene="YAT1"
                     /locus_tag="YAR035W"
                     /EC_number="2.3.1.7"
                     /note="Outer mitochondrial carnitine acetyltransferase;
                     minor ethanol-inducible enzyme involved in transport of
                     activated acyl groups from the cytoplasm into the
                     mitochondrial matrix; phosphorylated"
                     /codon_start=1
                     /product="carnitine O-acetyltransferase YAT1"
                     /protein_id="NP_009420.1"
                     /db_xref="GeneID:851285"
                     /db_xref="SGD:S000000080"
                     /translation="MPNLKRLPIPPLQDTLNRYLARVEPLQDERQNRRTRRTVLSAEN
                     LDALNTLHERLLEYDARLAESNPESSYIEQFWYDAYLLYDATVVLNVNPYFQLQDDPT
                     IKDTPETAAQGPYGAHTVQVRRAARLTTSILKFIRQIRHGTLRTDTVRGKTPLSMDQY
                     ERLFGSSRIPPGPGEPSCHLQTDATSHHVVAMYRGQFYWFDVLDTRNEPIFATPEQLE
                     WNLYSIIMDAESAGSGSAPFGVFTTESRRVWSNIRDYLFHADDCTNWRNLKLIDSALF
                     VVCLDDVAFAADQQDELTRSMLCGTSTINLDPHQHQPPLNVQTGTCLNRWYDKLQLIV
                     TKNGKAGINFEHTGVDGHTVLRLATDIYTDSILSFARGVTKNVVDIFSDDDGKPSSSS
                     LASAAHSANLITIPRKLEWRTDNFLQSSLHFAETRISDLISQYEFVNLDFSNYGASHI
                     KTVFKCSPDAFVQQVFQVAYFALYGRFETVYEPAMTKAFQNGRTEAIRSVTGQSKLFV
                     KSLLDQDASDATKIQLLHDACTAHSQITRECSQGLGQDRHLYALYCLWNQWYKDKLEL
                     PPIFRDKSWTTMQNNVLSTSNCGNPCLKSFGFGPVTANGFGIGYIIRDHSVSVVVSSR
                     HRQTARFASLMEKSLLEIDRIFKRQQARAAKPAARTTASANTKSEDMKYLLSGYDYFD
                     VSVSG"
     gene            complement(<192337..>192417)
                     /locus_tag="YAR035C-A"
                     /db_xref="GeneID:1466430"
     mRNA            complement(<192337..>192417)
                     /locus_tag="YAR035C-A"
                     /product="hypothetical protein"
                     /transcript_id="NM_001184583.1"
                     /db_xref="GeneID:1466430"
     CDS             complement(192337..192417)
                     /locus_tag="YAR035C-A"
                     /note="hypothetical protein; identified by gene-trapping,
                     microarray-based expression analysis, and genome-wide
                     homology searching; predicted to have a role in cell
                     budding based on computational 'guilt by association'
                     analysis"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_878042.1"
                     /db_xref="GeneID:1466430"
                     /db_xref="SGD:S000028595"
                     /translation="MRLNYSRCYYSSQRRRQSLPKRFPLI"
     gene            <192619..>196185
                     /gene="SWH1"
                     /locus_tag="YAR042W"
                     /gene_synonym="OSH1; YAR044W"
                     /db_xref="GeneID:851286"
     mRNA            <192619..>196185
                     /gene="SWH1"
                     /locus_tag="YAR042W"
                     /gene_synonym="OSH1; YAR044W"
                     /product="oxysterol-binding protein related protein SWH1"
                     /transcript_id="NM_001178227.1"
                     /db_xref="GeneID:851286"
     CDS             192619..196185
                     /gene="SWH1"
                     /locus_tag="YAR042W"
                     /gene_synonym="OSH1; YAR044W"
                     /note="Protein similar to mammalian oxysterol-binding
                     protein; contains ankyrin repeats and FFAT motif;
                     interacts with ER anchor Scs2p at the nucleus-vacuole
                     junction; regulated by sterol binding; SWH1 has a paralog,
                     OSH2, that arose from the whole genome duplication"
                     /codon_start=1
                     /product="oxysterol-binding protein related protein SWH1"
                     /protein_id="NP_009421.3"
                     /db_xref="GeneID:851286"
                     /db_xref="SGD:S000000081"
                     /translation="MEQPDLSSVAISKPLLKLKLLDALRQGSFPNLQDLLKKQFQPLD
                     DPNVQQVLHLMLHYAVQVAPMAVIKEIVHHWVSTTNTTFLNIHLDLNERDSNGNTPLH
                     IAAYQSRGDIVAFLLDQPTINDCVLNNSHLQAIEMCKNLNIAQMMQVKRSTYVAETAQ
                     EFRTAFNNRDFGHLESILSSPRNAELLDINGMDPETGDTVLHEFVKKRDVIMCRWLLE
                     HGADPFKRDRKGKLPIELVRKVNENDTATNTKIAIDIELKKLLERATREQSVIDVTNN
                     NLHEAPTYKGYLKKWTNFAQGYKLRWFILSSDGKLSYYIDQADTKNACRGSLNMSSCS
                     LHLDSSEKLKFEIIGGNNGVIRWHLKGNHPIETNRWVWAIQGAIRYAKDREILLHNGP
                     YSPSLALSHGLSSKVSNKENLHATSKRLTKSPHLSKSTLTQNDHDNDDDSTNNNNNKS
                     NNDYDDNNNNNNNDDDDYDDDDESRPLIEPLPLISSRSQSLSEITPGPHSRKSTVSST
                     RAADIPSDDEGYSEDDSDDDGNSSYTMENGGENDGDEDLNAIYGPYIQKLHMLQRSIS
                     IELASLNELLQDKQQHDEYWNTVNTSIETVSEFFDKLNRLTSQREKRMIAQMTKQRDV
                     NNVWIQSVKDLEMELVDKDEKLVALDKERKNLKKMLQKKLNNQPQVETEANEESDDAN
                     SMIKGSQESTNTLEEIVKFIEATKESDEDSDADEFFDAEEAASDKKANDSEDLTTNKE
                     TPANAKPQEEAPEDESLIVISSPQVEKKNQLLKEGSFVGYEDPVRTKLALDEDNRPKI
                     GLWSVLKSMVGQDLTKLTLPVSFNEPTSLLQRVSEDIEYSHILDQAATFEDSSLRMLY
                     VAAFTASMYASTTNRVSKPFNPLLGETFEYARTDGQYRFFTEQVSHHPPISATWTESP
                     KWDFYGECNVDSSFNGRTFAVQHLGLWYITIRPDHNISVPEETYSWKKPNNTVIGILM
                     GKPQVDNSGDVKVTNHTTGDYCMLHYKAHGWTSAGAYEVRGEVFNKDDKKLWVLGGHW
                     NDSIYGKKVTARGGELTLDRIKTANSATGGPKLDGSKFLIWKANERPSVPFNLTSFAL
                     TLNALPPHLIPYLAPTDSRLRPDQRAMENGEYDKAAAEKHRVEVKQRAAKKEREQKGE
                     EYRPKWFVQEEHPVTKSLYWKFNGEYWNKRKNHDFKDCADIF"
     gene            <203403..>208016
                     /gene="FLO1"
                     /locus_tag="YAR050W"
                     /gene_synonym="FLO2; FLO4"
                     /db_xref="GeneID:851289"
     mRNA            <203403..>208016
                     /gene="FLO1"
                     /locus_tag="YAR050W"
                     /gene_synonym="FLO2; FLO4"
                     /product="flocculin FLO1"
                     /transcript_id="NM_001178230.1"
                     /db_xref="GeneID:851289"
     CDS             203403..208016
                     /gene="FLO1"
                     /locus_tag="YAR050W"
                     /gene_synonym="FLO2; FLO4"
                     /note="Lectin-like protein involved in flocculation; cell
                     wall protein that binds mannose chains on the surface of
                     other cells, confers floc-forming ability that is
                     chymotrypsin sensitive and heat resistant; important for
                     co-flocculation with other yeasts, mediating interaction
                     with specific species; FLO1 has a paralog, FLO5, that
                     arose from a segmental duplication"
                     /codon_start=1
                     /product="flocculin FLO1"
                     /protein_id="NP_009424.1"
                     /db_xref="GeneID:851289"
                     /db_xref="SGD:S000000084"
                     /translation="MTMPHRYMFLAVFTLLALTSVASGATEACLPAGQRKSGMNINFY
                     QYSLKDSSTYSNAAYMAYGYASKTKLGSVGGQTDISIDYNIPCVSSSGTFPCPQEDSY
                     GNWGCKGMGACSNSQGIAYWSTDLFGFYTTPTNVTLEMTGYFLPPQTGSYTFKFATVD
                     DSAILSVGGATAFNCCAQQQPPITSTNFTIDGIKPWGGSLPPNIEGTVYMYAGYYYPM
                     KVVYSNAVSWGTLPISVTLPDGTTVSDDFEGYVYSFDDDLSQSNCTVPDPSNYAVSTT
                     TTTTEPWTGTFTSTSTEMTTVTGTNGVPTDETVIVIRTPTTASTIITTTEPWNSTFTS
                     TSTELTTVTGTNGVRTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTELTTVTGTNG
                     LPTDETIIVIRTPTTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTP
                     TTATTAMTTTQPWNDTFTSTSTELTTVTGTNGLPTDETIIVIRTPTTATTAMTTTQPW
                     NDTFTSTSTEITTVTGTNGLPTDETIIVIRTPTTATTAMTTPQPWNDTFTSTSTEMTT
                     VTGTNGLPTDETIIVIRTPTTATTAITTTEPWNSTFTSTSTEMTTVTGTNGLPTDETI
                     IVIRTPTTATTAITTTQPWNDTFTSTSTEMTTVTGTNGLPTDETIIVIRTPTTATTAM
                     TTTQPWNDTFTSTSTEITTVTGTTGLPTDETIIVIRTPTTATTAMTTTQPWNDTFTST
                     STEMTTVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQ
                     PTDETVIVIRTPTSEGLVTTTTEPWTGTFTSTSTEMTTITGTNGVPTDETVIVIRTPT
                     SEGLISTTTEPWTGTFTSTSTEMTTITGTNGQPTDETVIVIRTPTSEGLISTTTEPWT
                     GTFTSTSTEMTHVTGTNGVPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEVTTI
                     TGTNGQPTDETVIVIRTPTSEGLISTTTEPWTGTFTSTSTEMTTVTGTNGQPTDETVI
                     VIRTPTSEGLVTTTTEPWTGTFTSTSTEMSTVTGTNGLPTDETVIVVKTPTTAISSSL
                     SSSSSGQITSSITSSRPIITPFYPSNGTSVISSSVISSSVTSSLFTSSPVISSSVISS
                     STTTSTSIFSESSKSSVIPTSSSTSGSSESETSSAGSVSSSSFISSESSKSPTYSSSS
                     LPLVTSATTSQETASSLPPATTTKTSEQTTLVTVTSCESHVCTESISPAIVSTATVTV
                     SGVTTEYTTWCPISTTETTKQTKGTTEQTTETTKQTTVVTISSCESDVCSKTASPAIV
                     STSTATINGVTTEYTTWCPISTTESRQQTTLVTVTSCESGVCSETASPAIVSTATATV
                     NDVVTVYPTWRPQTANEESVSSKMNSATGETTTNTLAAETTTNTVAAETITNTGAAET
                     KTVVTSSLSRSNHAETQTASATDVIGHSSSVVSVSETGNTKSLTSSGLSTMSQQPRST
                     PASSMVGYSTASLEISTYAGSANSLLAGSGLSVFIASLLLAII"
     repeat_region   complement(209448..209778)
                     /note="Ty1 LTR"
                     /rpt_type=long_terminal_repeat
                     /db_xref="SGD:S000006791"
     rep_origin      214888..215644
                     /note="ARS111;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121256"
     gene            218140..219145
                     /locus_tag="YAR061W"
                     /gene_synonym="YAR062W"
                     /note="Pseudogenic fragment with similarity to flocculins;
                     YAR061W has a paralog, YHR212W-A, that arose from a
                     segmental duplication"
                     /pseudo
                     /db_xref="GeneID:851292"
                     /db_xref="SGD:S000000087"
     mRNA            218140..219145
                     /locus_tag="YAR061W"
                     /gene_synonym="YAR062W"
                     /pseudo
                     /db_xref="GeneID:851292"
                     /db_xref="SGD:S000000087"
     gene            <220198..>220497
                     /locus_tag="YAR064W"
                     /db_xref="GeneID:851294"
     mRNA            <220198..>220497
                     /locus_tag="YAR064W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001178235.1"
                     /db_xref="GeneID:851294"
     CDS             220198..220497
                     /locus_tag="YAR064W"
                     /note="Pseudogenic fragment with similarity to flocculins;
                     YAR064W has a paralog, YHR213W-B, that arose from a
                     segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009429.1"
                     /db_xref="GeneID:851294"
                     /db_xref="SGD:S000000089"
                     /translation="MLIDFCCSYIAGTHGRERAPSFTGTFVSHVSGENNCRPRRSEIT
                     QPCASGTEKKHFAATEKPCTNSLEGSRKDFLSLPLGHSYLFLFCFWRMICSEPKL"
     gene            <221049..>221660
                     /locus_tag="YAR066W"
                     /db_xref="GeneID:851295"
     mRNA            <221049..>221660
                     /locus_tag="YAR066W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001180045.1"
                     /db_xref="GeneID:851295"
     CDS             221049..221660
                     /locus_tag="YAR066W"
                     /note="Putative GPI protein; SWAT-GFP and mCherry fusion
                     proteins localize to the endoplasmic reticulum and vacuole
                     respectively; YAR066W has a paralog, YHR214W, that arose
                     from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009430.1"
                     /db_xref="GeneID:851295"
                     /db_xref="SGD:S000002144"
                     /translation="MFNRFNKFQAAVALALLSRGALGDSYTNSTSSADLSSITSVSSA
                     SASATASDSLSSSDGTVYLPSTTISGDLTVTGKVIATEAVEVAAGGKLTLLDGEKYVF
                     SSDLKVHGDLVVEKSEASYEGTAFDVSGETFEVSGNFSAEETGAVSASIYSFTPSSFK
                     SSGDISLSLSKAKKGEVTFSPYSNAGTFSLSNAILNGGSVSGL"
     gene            <222406..>222891
                     /locus_tag="YAR068W"
                     /db_xref="GeneID:851296"
     mRNA            <222406..>222891
                     /locus_tag="YAR068W"
                     /product="hypothetical protein"
                     /transcript_id="NM_001178236.1"
                     /db_xref="GeneID:851296"
     CDS             222406..222891
                     /locus_tag="YAR068W"
                     /note="Fungal-specific hypothetical protein; induced in
                     respiratory-deficient cells; YAR068W has a paralog,
                     YHR214W-A, that arose from a segmental duplication"
                     /codon_start=1
                     /product="hypothetical protein"
                     /protein_id="NP_009431.1"
                     /db_xref="GeneID:851296"
                     /db_xref="SGD:S000000091"
                     /translation="MPQVQSWFPVQKQPTLAVTFTPLPQLSHAHLPLPPSHLVTKTDA
                     MFQHQLLPTQLQPFPPSHTPLLLLLTVTTMAVTPRLSLLNVLKKLQQPPFLQNHTLLL
                     PLLTVTTTAVTPRLSLPRLPNKHHWPLAQSPSLLLQLLILLLPAPSLVLSFNPKVWLL
                     V"
     rep_origin      222880..224046
                     /note="ARS112;
                     Autonomously Replicating Sequence"
                     /db_xref="SGD:S000121257"
     gene            <225460..>226863
                     /gene="PHO11"
                     /locus_tag="YAR071W"
                     /db_xref="GeneID:851299"
     mRNA            <225460..>226863
                     /gene="PHO11"
                     /locus_tag="YAR071W"
                     /product="acid phosphatase PHO11"
                     /transcript_id="NM_001178239.1"
                     /db_xref="GeneID:851299"
     CDS             225460..226863
                     /gene="PHO11"
                     /locus_tag="YAR071W"
                     /EC_number="3.1.3.2"
                     /note="One of three repressible acid phosphatases;
                     glycoprotein that is transported to the cell surface by
                     the secretory pathway; induced by phosphate starvation and
                     coordinately regulated by PHO4 and PHO2; PHO11 has a
                     paralog, PHO12, that arose from a segmental duplication"
                     /codon_start=1
                     /product="acid phosphatase PHO11"
                     /protein_id="NP_009434.1"
                     /db_xref="GeneID:851299"
                     /db_xref="SGD:S000000094"
                     /translation="MLKSAVYSILAASLVNAGTIPLGKLSDIDKIGTQTEIFPFLGGS
                     GPYYSFPGDYGISRDLPESCEMKQVQMVGRHGERYPTVSKAKSIMTTWYKLSNYTGQF
                     SGALSFLNDDYEFFIRDTKNLEMETTLANSVNVLNPYTGEMNAKRHARDFLAQYGYMV
                     ENQTSFAVFTSNSNRCHDTAQYFIDGLGDKFNISLQTISEAESAGANTLSAHHSCPAW
                     DDDVNDDILKKYDTKYLSGIAKRLNKENKGLNLTSSDANTFFAWCAYEINARGYSDIC
                     NIFTKDELVRFSYGQDLETYYQTGPGYDVVRSVGANLFNASVKLLKESEVQDQKVWLS
                     FTHDTDILNYLTTIGIIDDKNNLTAEHVPFMENTFHRSWYVPQGARVYTEKFQCSNDT
                     YVRYVINDAVVPIETCSTGPGFSCEINDFYDYAEKRVAGTDFLKVCNVSSVSNSTELT
                     FFWDWNTKHYNDTLLKQ"
     telomere        229411..230218
                     /note="TEL01R; Telomeric region on the right arm of
                     Chromosome I; composed of an X element core sequence and a
                     short terminal stretch of telomeric repeats"
                     /db_xref="SGD:S000028937"
CONTIG      join(BK006935.2:1..230218)
//

