Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: BONFERRONI Bonferroni count: 9152 GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (38) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) fatty-acyl-CoA biosynthetic process (GO:0046949) 28 25 .05 + > 100 3.72E-66 acyl-CoA biosynthetic process (GO:0071616) 43 26 .08 + > 100 3.00E-61 thioester biosynthetic process (GO:0035384) 43 26 .08 + > 100 3.00E-61 fatty-acyl-CoA metabolic process (GO:0035337) 41 25 .08 + > 100 1.16E-58 fatty acid derivative biosynthetic process (GO:1901570) 62 25 .11 + > 100 1.64E-52 long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) 19 19 .04 + > 100 4.40E-51 fatty acid metabolic process (GO:0006631) 330 33 .61 + 54.16 4.91E-51 acyl-CoA metabolic process (GO:0006637) 92 26 .17 + > 100 3.93E-50 thioester metabolic process (GO:0035383) 92 26 .17 + > 100 3.93E-50 fatty acid biosynthetic process (GO:0006633) 130 27 .24 + > 100 2.39E-48 fatty acid derivative metabolic process (GO:1901568) 85 25 .16 + > 100 2.39E-48 monocarboxylic acid biosynthetic process (GO:0072330) 176 28 .32 + 86.16 5.32E-47 long-chain fatty-acyl-CoA metabolic process (GO:0035336) 25 19 .05 + > 100 7.74E-46 lipid biosynthetic process (GO:0008610) 589 34 1.09 + 31.26 7.95E-45 monocarboxylic acid metabolic process (GO:0032787) 509 33 .94 + 35.11 1.39E-44 sulfur compound biosynthetic process (GO:0044272) 149 26 .28 + 94.50 5.22E-44 amide biosynthetic process (GO:0043604) 155 26 .29 + 90.85 1.60E-43 carboxylic acid biosynthetic process (GO:0046394) 268 28 .49 + 56.58 1.48E-41 organic acid biosynthetic process (GO:0016053) 271 28 .50 + 55.96 2.06E-41 carboxylic acid metabolic process (GO:0019752) 766 33 1.41 + 23.33 1.35E-38 lipid metabolic process (GO:0006629) 1211 36 2.24 + 16.10 1.79E-38 purine-containing compound biosynthetic process (GO:0072522) 241 26 .44 + 58.43 3.34E-38 oxoacid metabolic process (GO:0043436) 788 33 1.46 + 22.68 3.48E-38 organic acid metabolic process (GO:0006082) 796 33 1.47 + 22.45 4.87E-38 small molecule biosynthetic process (GO:0044283) 466 29 .86 + 33.70 1.02E-36 nucleoside phosphate biosynthetic process (GO:1901293) 299 26 .55 + 47.09 1.16E-35 very long-chain fatty acid metabolic process (GO:0000038) 35 17 .06 + > 100 1.97E-35 sulfur compound metabolic process (GO:0006790) 314 26 .58 + 44.84 4.35E-35 small molecule metabolic process (GO:0044281) 1576 36 2.91 + 12.37 2.56E-34 very long-chain fatty acid biosynthetic process (GO:0042761) 13 13 .02 + > 100 2.61E-33 fatty acid elongation (GO:0030497) 14 13 .03 + > 100 3.65E-32 amide metabolic process (GO:0043603) 412 26 .76 + 34.18 6.22E-32 purine-containing compound metabolic process (GO:0072521) 506 26 .93 + 27.83 1.44E-29 organophosphate biosynthetic process (GO:0090407) 567 26 1.05 + 24.83 2.87E-28 nucleoside phosphate metabolic process (GO:0006753) 582 26 1.07 + 24.19 5.70E-28 nucleobase-containing small molecule metabolic process (GO:0055086) 609 26 1.12 + 23.12 1.87E-27 organophosphate metabolic process (GO:0019637) 977 26 1.80 + 14.41 4.03E-22 fatty acid elongation, saturated fatty acid (GO:0019367) 8 8 .01 + > 100 5.62E-19 long-chain fatty acid metabolic process (GO:0001676) 111 14 .20 + 68.31 5.99E-19 biosynthetic process (GO:0009058) 3997 35 7.38 + 4.74 4.52E-18 phosphate-containing compound metabolic process (GO:0006796) 1427 26 2.63 + 9.87 6.50E-18 phosphorus metabolic process (GO:0006793) 1430 26 2.64 + 9.85 6.86E-18 nucleobase-containing compound biosynthetic process (GO:0034654) 1793 27 3.31 + 8.16 8.60E-17 fatty acid elongation, unsaturated fatty acid (GO:0019368) 7 7 .01 + > 100 3.73E-16 fatty acid elongation, polyunsaturated fatty acid (GO:0034626) 7 7 .01 + > 100 3.73E-16 fatty acid elongation, monounsaturated fatty acid (GO:0034625) 7 7 .01 + > 100 3.73E-16 unsaturated fatty acid biosynthetic process (GO:0006636) 49 10 .09 + > 100 9.04E-15 sphingolipid metabolic process (GO:0006665) 162 13 .30 + 43.46 1.14E-14 membrane lipid metabolic process (GO:0006643) 208 13 .38 + 33.85 3.12E-13 primary metabolic process (GO:0044238) 6778 37 12.52 + 2.96 3.15E-13 metabolic process (GO:0008152) 7642 38 14.11 + 2.69 3.87E-13 sphingolipid biosynthetic process (GO:0030148) 106 11 .20 + 56.20 3.90E-13 unsaturated fatty acid metabolic process (GO:0033559) 110 11 .20 + 54.16 5.95E-13 nucleobase-containing compound metabolic process (GO:0006139) 2748 27 5.07 + 5.32 5.40E-12 membrane lipid biosynthetic process (GO:0046467) 145 11 .27 + 41.09 1.35E-11 alpha-linolenic acid metabolic process (GO:0036109) 16 5 .03 + > 100 6.43E-07 long-chain fatty acid biosynthetic process (GO:0042759) 40 6 .07 + 81.24 8.79E-07 linoleic acid metabolic process (GO:0043651) 22 5 .04 + > 100 3.85E-06 olefinic compound metabolic process (GO:0120254) 150 7 .28 + 25.27 9.07E-05 long-chain fatty acid import into cell (GO:0044539) 11 3 .02 + > 100 8.68E-03 lipid import into cell (GO:0140354) 15 3 .03 + > 100 2.38E-02 positive regulation of long-chain fatty acid import across plasma membrane (GO:0010747) 2 2 .00 + > 100 3.04E-02