Lee MN, Jung EY, Kwun HJ, Jun HK, Yu DY, et al. (2002) Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway. J Gen Virol 83: 2145–2151. Yamanaka T, Uchida M, Doi T (2002) Innate form of HCV core protein plays an important role in the localization and the function of HCV core protein. Biochem Biophys Res Commun 294: 521–527. doi: 10.1016/S0006-291X(02)00507-7. Nguyen H, Mudryj M, Guadalupe M, Dandekar S (2003) Hepatitis C virus core protein expression leads to biphasic regulation of the p21 cdk inhibitor and modulation of hepatocyte cell cycle. Virology 312: 245–253. doi: 10.1016/S0042-6822(03)00209-5. Ohkawa K, Ishida H, Nakanishi F, Hosui A, Ueda K, et al. (2004) Hepatitis C virus core functions as a suppressor of cyclin-dependent kinase-activating kinase and impairs cell cycle progression. J Biol Chem 279: 11719–11726. doi: 10.1074/jbc.M308560200.