UNIVERSITY OF MICHIGAN | COLLEGE OF PHARMACY | MOSBERG LAB
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2V50 » Multidrug exporter MexB
2v50 » Multidrug exporter MexB
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Topology in Bacterial gram-negative inner membrane
Topology	periplasmic side
cytoplasmic side

    * Type: 1. Transmembrane (2 classes)
    * Class: 1.1. Alpha-helical transmembrane (57 superfamilies)
    * Superfamily: 1.1.15. Resistance-nodulation-cell division (1 family) 2.A.6 (TCDB)
    * Family: 1.1.15.01. Multidrug efflux transporter (3 proteins) 2.A.6 (TCDB)
    * Species: Pseudomonas aeruginosa (12 proteins)
    * Localization: Bacterial gram-negative inner membrane (127 proteins)

2v50 » Multidrug exporter MexB
Hydrophobic Thickness 	27.5 ± 0.8 ?
Tilt Angle 	0 ± 1°
?Gtransfer 	-189.7 kcal/mol
Links to 2v50 	PDB Sum, SCOP, MSD, OCA, MMDB, Dali
Topology 	subunit A (N-terminus cytoplasmic)
Resolution 	3.0 ?
Related PDB Sum entries 	none
Number of TM Secondary Structures 	36
3 transmembrane subunits
A - Tilt: 2° - Segments: 1( 9- 27), 2( 340- 359), 3( 362- 386), 4( 394- 411), 5( 440- 458), 6( 467- 489), 7( 539- 556), 8( 873- 891), 9( 895- 918), 10( 926- 943), 11( 972- 988), 12(1000-1020)
B - Tilt: 5° - Segments: 1( 9- 27), 2( 340- 358), 3( 362- 382), 4( 397- 414), 5( 438- 456), 6( 471- 493), 7( 539- 556), 8( 874- 891), 9( 895- 915), 10( 926- 946), 11( 969- 988), 12(1001-1024)
C - Tilt: 3° - Segments: 1( 10- 28), 2( 341- 359), 3( 362- 386), 4( 394- 413), 5( 440- 458), 6( 470- 489), 7( 539- 556), 8( 873- 891), 9( 895- 918), 10( 926- 946), 11( 972- 988), 12(1001-1020)

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University of Michigan, Ann Arbor, MI 48109 USA
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