base A T G C freq expected 0.323 0.323 0.177 0.177 pseudocounts 0.1 0.1 0.1 0.1 0.02128 0.02193 0.01776 0.01284 0.02187 0.02175 0.01665 0.0132 0.02106 0.02068 0.01878 0.01628 0.02175 0.02114 0.01628 0.01646 0.02181 0.02091 0.01761 0.01522 0.02162 0.02142 0.01746 0.01445 0.022 0.0206 0.01746 0.01567 0.02181 0.02135 0.01731 0.01417 0.02257 0.0206 0.01682 0.01417 0.02217 0.02052 0.01608 0.01682 0.02318 0.02027 0.01545 0.01387 0.02293 0.02001 0.01715 0.01355 0.02337 0.01991 0.01588 0.0132 0.02273 0.0206 0.01628 0.01417 0.02268 0.0206 0.01608 0.01472 0.02251 0.02106 0.01567 0.01445 0.02235 0.02114 0.01628 0.01417 0.02212 0.02114 0.01665 0.01472 0.02212 0.02121 0.01715 0.01355 0.02155 0.02091 0.01776 0.01588 0.02262 0.01982 0.01829 0.01355 0.02303 0.01901 0.01866 0.01244 0.02273 0.01901 0.01889 0.01387 0.02293 0.01803 0.02001 0.01102 0.02135 0.01776 0.02181 0.0132 0.02036 0.01646 0.02318 0.01154 0.02099 0.01545 0.02313 0.01044 0.02044 0.01628 0.02337 0.00902 0.01991 0.01731 0.02341 0.00813 0.02099 0.01761 0.02251 0.01044 0.01991 0.01943 0.02206 0.0132 0.02168 0.01963 0.02044 0.01244 0.0224 0.02027 0.01842 0.01284 0.02206 0.02076 0.01854 0.01244 0.02206 0.02121 0.01776 0.01244 0.02212 0.02121 0.01699 0.01387 0.02313 0.01889 0.01731 0.01522 0.02364 0.01842 0.01646 0.01472 0.02268 0.01912 0.01943 0.01201 0.02523 0.01646 0.01387 -0.01149 0.00048 0.02642 -0.01149-0.01149 0.00048 0.00048 0.02639 -0.01149