Analysis Type: PANTHER Overrepresentation Test (Released 20210224) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.4495804 Released 2021-02-01 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20595) upload_1 (14) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) carbohydrate derivative catabolic process (GO:1901136) 196 10 .13 + 75.05 7.73E-18 1.22E-13 carbohydrate derivative metabolic process (GO:1901135) 1006 13 .68 + 19.01 1.31E-16 1.03E-12 liposaccharide metabolic process (GO:1903509) 111 7 .08 + 92.77 5.59E-13 1.76E-09 glycolipid metabolic process (GO:0006664) 110 7 .07 + 93.61 5.26E-13 2.08E-09 keratan sulfate catabolic process (GO:0042340) 12 5 .01 + > 100 3.98E-13 2.09E-09 glycolipid catabolic process (GO:0019377) 15 5 .01 + > 100 9.97E-13 2.62E-09 granulocyte activation (GO:0036230) 499 9 .34 + 26.53 5.62E-12 6.33E-09 neutrophil activation (GO:0042119) 495 9 .34 + 26.75 5.24E-12 6.35E-09 leukocyte degranulation (GO:0043299) 506 9 .34 + 26.17 6.35E-12 6.68E-09 aminoglycan catabolic process (GO:0006026) 68 6 .05 + > 100 5.11E-12 6.72E-09 glycosaminoglycan catabolic process (GO:0006027) 62 6 .04 + > 100 3.03E-12 6.82E-09 neutrophil activation involved in immune response (GO:0002283) 486 9 .33 + 27.24 4.45E-12 7.03E-09 neutrophil mediated immunity (GO:0002446) 493 9 .34 + 26.86 5.05E-12 7.24E-09 myeloid leukocyte mediated immunity (GO:0002444) 515 9 .35 + 25.71 7.42E-12 7.31E-09 glycosphingolipid metabolic process (GO:0006687) 66 6 .04 + > 100 4.32E-12 7.56E-09 myeloid cell activation involved in immune response (GO:0002275) 524 9 .36 + 25.27 8.64E-12 8.02E-09 neutrophil degranulation (GO:0043312) 482 9 .33 + 27.47 4.14E-12 8.17E-09 myeloid leukocyte activation (GO:0002274) 587 9 .40 + 22.55 2.35E-11 2.06E-08 keratan sulfate metabolic process (GO:0042339) 33 5 .02 + > 100 3.21E-11 2.66E-08 leukocyte activation involved in immune response (GO:0002366) 630 9 .43 + 21.02 4.37E-11 3.28E-08 cell activation involved in immune response (GO:0002263) 634 9 .43 + 20.88 4.62E-11 3.31E-08 membrane lipid metabolic process (GO:0006643) 210 7 .14 + 49.04 4.20E-11 3.31E-08 membrane lipid catabolic process (GO:0046466) 37 5 .03 + > 100 5.43E-11 3.72E-08 regulated exocytosis (GO:0045055) 693 9 .47 + 19.10 1.01E-10 6.63E-08 leukocyte mediated immunity (GO:0002443) 755 9 .51 + 17.54 2.14E-10 1.35E-07 carbohydrate metabolic process (GO:0005975) 474 8 .32 + 24.83 2.24E-10 1.36E-07 exocytosis (GO:0006887) 785 9 .53 + 16.87 3.01E-10 1.76E-07 glycosphingolipid catabolic process (GO:0046479) 13 4 .01 + > 100 3.15E-10 1.78E-07 sulfur compound catabolic process (GO:0044273) 55 5 .04 + > 100 3.46E-10 1.88E-07 glycosaminoglycan metabolic process (GO:0030203) 152 6 .10 + 58.07 5.27E-10 2.68E-07 organic substance catabolic process (GO:1901575) 1761 11 1.20 + 9.19 5.26E-10 2.77E-07 sphingolipid metabolic process (GO:0006665) 162 6 .11 + 54.48 7.63E-10 3.76E-07 aminoglycan metabolic process (GO:0006022) 166 6 .11 + 53.17 8.80E-10 4.21E-07 ceramide catabolic process (GO:0046514) 20 4 .01 + > 100 1.40E-09 6.33E-07 leukocyte activation (GO:0045321) 935 9 .64 + 14.16 1.39E-09 6.45E-07 secretion by cell (GO:0032940) 948 9 .64 + 13.97 1.57E-09 6.88E-07 export from cell (GO:0140352) 996 9 .68 + 13.29 2.42E-09 1.03E-06 catabolic process (GO:0009056) 2084 11 1.42 + 7.76 3.18E-09 1.32E-06 secretion (GO:0046903) 1061 9 .72 + 12.48 4.19E-09 1.70E-06 organonitrogen compound catabolic process (GO:1901565) 1080 9 .73 + 12.26 4.89E-09 1.93E-06 cell activation (GO:0001775) 1084 9 .74 + 12.21 5.05E-09 1.94E-06 immune effector process (GO:0002252) 1095 9 .74 + 12.09 5.52E-09 2.07E-06 sphingolipid catabolic process (GO:0030149) 32 4 .02 + > 100 7.75E-09 2.84E-06 mucopolysaccharide metabolic process (GO:1903510) 109 5 .07 + 67.48 9.12E-09 3.27E-06 lipid catabolic process (GO:0016042) 304 6 .21 + 29.03 2.99E-08 1.03E-05 ganglioside catabolic process (GO:0006689) 7 3 .00 + > 100 2.99E-08 1.05E-05 glycoside catabolic process (GO:0016139) 11 3 .01 + > 100 9.04E-08 3.04E-05 cellular lipid catabolic process (GO:0044242) 200 5 .14 + 36.78 1.73E-07 5.67E-05 organonitrogen compound metabolic process (GO:1901564) 5251 13 3.57 + 3.64 2.08E-07 6.70E-05 lipid metabolic process (GO:0006629) 1222 8 .83 + 9.63 3.42E-07 1.08E-04 cellular catabolic process (GO:0044248) 1797 9 1.22 + 7.37 3.98E-07 1.23E-04 ceramide metabolic process (GO:0006672) 93 4 .06 + 63.27 4.45E-07 1.35E-04 glycoside metabolic process (GO:0016137) 22 3 .01 + > 100 5.69E-07 1.69E-04 vesicle-mediated transport (GO:0016192) 1958 9 1.33 + 6.76 8.28E-07 2.42E-04 immune response (GO:0006955) 1972 9 1.34 + 6.71 8.80E-07 2.52E-04 ganglioside metabolic process (GO:0001573) 26 3 .02 + > 100 9.02E-07 2.54E-04 carbohydrate catabolic process (GO:0016052) 116 4 .08 + 50.73 1.05E-06 2.89E-04 cellular lipid metabolic process (GO:0044255) 975 7 .66 + 10.56 1.40E-06 3.80E-04 organic substance metabolic process (GO:0071704) 7878 14 5.36 + 2.61 1.45E-06 3.87E-04 metabolic process (GO:0008152) 8333 14 5.66 + 2.47 3.18E-06 8.35E-04 sulfur compound metabolic process (GO:0006790) 369 5 .25 + 19.93 3.35E-06 8.67E-04 establishment of localization in cell (GO:0051649) 2365 9 1.61 + 5.60 4.09E-06 1.04E-03 glycosyl compound catabolic process (GO:1901658) 45 3 .03 + 98.07 4.24E-06 1.06E-03 nitrogen compound metabolic process (GO:0006807) 6897 13 4.69 + 2.77 6.48E-06 1.60E-03 oligosaccharide metabolic process (GO:0009311) 64 3 .04 + 68.96 1.17E-05 2.83E-03 male mating behavior (GO:0060179) 7 2 .00 + > 100 1.54E-05 3.68E-03 immune system process (GO:0002376) 2849 9 1.94 + 4.65 1.94E-05 4.56E-03 cellular metabolic process (GO:0044237) 7570 13 5.15 + 2.53 2.08E-05 4.82E-03 cellular localization (GO:0051641) 3003 9 2.04 + 4.41 2.99E-05 6.84E-03 macromolecule catabolic process (GO:0009057) 1046 6 .71 + 8.44 3.68E-05 8.28E-03 oligosaccharide catabolic process (GO:0009313) 13 2 .01 + > 100 4.48E-05 9.95E-03 chondroitin sulfate catabolic process (GO:0030207) 14 2 .01 + > 100 5.11E-05 1.12E-02 fucose metabolic process (GO:0006004) 16 2 .01 + > 100 6.52E-05 1.41E-02 hyaluronan catabolic process (GO:0030214) 18 2 .01 + > 100 8.09E-05 1.72E-02 mating behavior (GO:0007617) 19 2 .01 + > 100 8.93E-05 1.88E-02 glycosyl compound metabolic process (GO:1901657) 132 3 .09 + 33.43 9.49E-05 1.94E-02 glycoprotein metabolic process (GO:0009100) 372 4 .25 + 15.82 9.44E-05 1.96E-02 cellular amide metabolic process (GO:0043603) 808 5 .55 + 9.10 1.40E-04 2.84E-02 hexose metabolic process (GO:0019318) 156 3 .11 + 28.29 1.54E-04 3.08E-02 reproductive behavior (GO:0019098) 27 2 .02 + > 100 1.72E-04 3.39E-02 primary metabolic process (GO:0044238) 7363 12 5.01 + 2.40 1.79E-04 3.49E-02 mating (GO:0007618) 32 2 .02 + 91.94 2.37E-04 4.46E-02 monosaccharide metabolic process (GO:0005996) 180 3 .12 + 24.52 2.33E-04 4.49E-02 protein deglycosylation (GO:0006517) 32 2 .02 + 91.94 2.37E-04 4.51E-02 hyaluronan metabolic process (GO:0030212) 33 2 .02 + 89.16 2.52E-04 4.67E-02