ID   A3PS35_RHOS1            Unreviewed;       278 AA.
AC   A3PS35;
DT   03-APR-2007, integrated into UniProtKB/TrEMBL.
DT   03-APR-2007, sequence version 1.
DT   04-MAR-2015, entry version 56.
DE   RecName: Full=2-dehydro-3-deoxyphosphooctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056, ECO:0000256|SAAS:SAAS00078566};
DE            EC=2.5.1.55 {ECO:0000256|HAMAP-Rule:MF_00056, ECO:0000256|SAAS:SAAS00078538};
DE   AltName: Full=3-deoxy-D-manno-octulosonic acid 8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=KDO-8-phosphate synthase {ECO:0000256|HAMAP-Rule:MF_00056};
DE   AltName: Full=Phospho-2-dehydro-3-deoxyoctonate aldolase {ECO:0000256|HAMAP-Rule:MF_00056};
GN   Name=kdsA {ECO:0000256|HAMAP-Rule:MF_00056};
GN   OrderedLocusNames=Rsph17029_4073 {ECO:0000313|EMBL:ABN79151.1};
OS   Rhodobacter sphaeroides (strain ATCC 17029 / ATH 2.4.9).
OG   Plasmid pRSPH01 {ECO:0000313|EMBL:ABN79151.1,
OG   ECO:0000313|Proteomes:UP000002606}.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=349101 {ECO:0000313|EMBL:ABN79151.1, ECO:0000313|Proteomes:UP000002606};
RN   [1] {ECO:0000313|Proteomes:UP000002606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 17029 / ATH 2.4.9 {ECO:0000313|Proteomes:UP000002606};
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Hammon N., Israni S., Dalin E., Tice H.,
RA   Pitluck S., Kiss H., Brettin T., Bruce D., Han C., Tapia R., Gilna P.,
RA   Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Richardson P., Mackenzie C., Choudhary M.,
RA   Donohue T.J., Kaplan S.;
RT   "Complete sequence of plasmid pRSPH01 of Rhodobacter sphaeroides ATCC
RT   17029.";
RL   Submitted (FEB-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Phosphoenolpyruvate + D-arabinose 5-phosphate
CC       + H(2)O = 2-dehydro-3-deoxy-D-octonate 8-phosphate + phosphate.
CC       {ECO:0000256|HAMAP-Rule:MF_00056, ECO:0000256|SAAS:SAAS00078594}.
CC   -!- PATHWAY: Bacterial outer membrane biogenesis; lipopolysaccharide
CC       biosynthesis. {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00078549}.
CC   -!- PATHWAY: Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate
CC       biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-
CC       phosphate: step 2/3. {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00078570}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
CC       ECO:0000256|SAAS:SAAS00078569}.
CC   -!- SIMILARITY: Belongs to the KdsA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00056}.
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DR   EMBL; CP000579; ABN79151.1; -; Genomic_DNA.
DR   RefSeq; YP_001041787.1; NC_009040.1.
DR   ProteinModelPortal; A3PS35; -.
DR   STRING; 349101.Rsph17029_4073; -.
DR   EnsemblBacteria; ABN79151; ABN79151; Rsph17029_4073.
DR   GeneID; 4894991; -.
DR   KEGG; rsh:Rsph17029_4073; -.
DR   PATRIC; 23167351; VBIRhoSph114483_0007.
DR   eggNOG; COG2877; -.
DR   HOGENOM; HOG000023021; -.
DR   KO; K01627; -.
DR   OMA; MSQGNGQ; -.
DR   OrthoDB; EOG680X4R; -.
DR   BioCyc; RSPH349101:GHC8-4142-MONOMER; -.
DR   UniPathway; UPA00030; -.
DR   UniPathway; UPA00357; UER00474.
DR   Proteomes; UP000002606; Plasmid pRSPH01.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0008676; F:3-deoxy-8-phosphooctulonate synthase activity; IEA:UniProtKB-HAMAP.
DR   GO; GO:0019294; P:keto-3-deoxy-D-manno-octulosonic acid biosynthetic process; IEA:UniProtKB-HAMAP.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_00056; KDO8P_synth; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR006218; DAHP1/KDSA.
DR   InterPro; IPR006269; KDO8P_synthase.
DR   PANTHER; PTHR21057:SF2; PTHR21057:SF2; 1.
DR   Pfam; PF00793; DAHP_synth_1; 1.
DR   TIGRFAMs; TIGR01362; KDO8P_synth; 1.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000002606};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00078532};
KW   Lipopolysaccharide biosynthesis {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00078551}; Plasmid {ECO:0000313|EMBL:ABN79151.1};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00056,
KW   ECO:0000256|SAAS:SAAS00080156}.
SQ   SEQUENCE   278 AA;  29363 MW;  BB3A967A8207AAEC CRC64;
     MTETPTIVTI GDIAIGGGHP IALITGPCQL ESLDHARMMA ERIAEACAPT GTKFIFKASY
     DKANRSSLST ARGLGMEKGL EILGRIREEF GVPVLTDVHE PGHCATAAEV CDVLQIPAFL
     CRQTDLLLAA GETGRAVNVK KGQFLAPWDM KNVADKVAST GNRRILLCER GTSFGYNTLV
     TDFRGLPTMA ATGWPVVFDA THSVQQPGGL GGSSGGQREF APVLARAACA VGVSALFIET
     HEDPDRAPSD GPNMIPVDRM GRLIADLCAF DALAKSLA
//