Analysis Type: PANTHER Overrepresentation Test (Released 20221013) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.7709866 Released 2023-03-06 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20589) upload_1 (17) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) metabolic process (GO:0008152) 8105 16 6.69 + 2.39 3.59E-06 7.19E-04 organic substance metabolic process (GO:0071704) 7694 16 6.35 + 2.52 1.61E-06 3.35E-04 primary metabolic process (GO:0044238) 7199 16 5.94 + 2.69 5.76E-07 1.27E-04 nitrogen compound metabolic process (GO:0006807) 6649 16 5.49 + 2.91 1.68E-07 3.79E-05 cellular metabolic process (GO:0044237) 5808 16 4.80 + 3.34 2.04E-08 4.75E-06 organonitrogen compound metabolic process (GO:1901564) 4908 16 4.05 + 3.95 1.46E-09 3.62E-07 cellular nitrogen compound metabolic process (GO:0034641) 3344 16 2.76 + 5.79 3.49E-12 9.73E-10 organic cyclic compound metabolic process (GO:1901360) 3255 16 2.69 + 5.95 2.28E-12 6.72E-10 cellular aromatic compound metabolic process (GO:0006725) 3014 16 2.49 + 6.43 6.77E-13 2.07E-10 heterocycle metabolic process (GO:0046483) 2969 16 2.45 + 6.53 5.34E-13 1.70E-10 nucleobase-containing compound metabolic process (GO:0006139) 2794 16 2.31 + 6.94 2.04E-13 6.93E-11 biosynthetic process (GO:0009058) 2639 15 2.18 + 6.88 4.53E-12 1.22E-09 organic substance biosynthetic process (GO:1901576) 2577 15 2.13 + 7.05 3.19E-12 9.06E-10 cellular biosynthetic process (GO:0044249) 2221 15 1.83 + 8.18 3.59E-13 1.19E-10 phosphorus metabolic process (GO:0006793) 1841 16 1.52 + 10.53 2.78E-16 1.03E-13 phosphate-containing compound metabolic process (GO:0006796) 1815 16 1.50 + 10.68 2.22E-16 8.65E-14 small molecule metabolic process (GO:0044281) 1659 16 1.37 + 11.68 5.34E-17 2.45E-14 cellular nitrogen compound biosynthetic process (GO:0044271) 1627 8 1.34 + 5.96 1.96E-05 3.64E-03 organonitrogen compound biosynthetic process (GO:1901566) 1338 8 1.10 + 7.24 4.63E-06 9.04E-04 organic cyclic compound biosynthetic process (GO:1901362) 1238 8 1.02 + 7.83 2.60E-06 5.34E-04 lipid metabolic process (GO:0006629) 1227 16 1.01 + 15.79 4.50E-19 2.60E-16 aromatic compound biosynthetic process (GO:0019438) 1116 8 .92 + 8.68 1.19E-06 2.52E-04 heterocycle biosynthetic process (GO:0018130) 1106 8 .91 + 8.76 1.12E-06 2.39E-04 nucleobase-containing compound biosynthetic process (GO:0034654) 1035 8 .85 + 9.36 6.77E-07 1.47E-04 carbohydrate derivative metabolic process (GO:1901135) 981 16 .81 + 19.75 1.31E-20 8.15E-18 cellular lipid metabolic process (GO:0044255) 917 16 .76 + 21.13 4.49E-21 2.92E-18 organophosphate metabolic process (GO:0019637) 900 16 .74 + 21.53 3.34E-21 2.27E-18 organic acid metabolic process (GO:0006082) 868 16 .72 + 22.32 1.89E-21 1.40E-18 oxoacid metabolic process (GO:0043436) 861 16 .71 + 22.51 1.66E-21 1.29E-18 carboxylic acid metabolic process (GO:0019752) 839 16 .69 + 23.10 1.10E-21 9.56E-19 amide metabolic process (GO:0043603) 792 16 .65 + 24.47 4.43E-22 4.07E-19 lipid biosynthetic process (GO:0008610) 604 15 .50 + 30.08 1.59E-21 1.31E-18 carbohydrate derivative biosynthetic process (GO:1901137) 600 8 .50 + 16.15 1.05E-08 2.49E-06 nucleobase-containing small molecule metabolic process (GO:0055086) 560 16 .46 + 34.60 1.88E-24 1.83E-21 organophosphate biosynthetic process (GO:0090407) 547 8 .45 + 17.71 5.17E-09 1.24E-06 amide biosynthetic process (GO:0043604) 536 8 .44 + 18.08 4.42E-09 1.08E-06 monocarboxylic acid metabolic process (GO:0032787) 522 16 .43 + 37.12 6.21E-25 6.46E-22 nucleoside phosphate metabolic process (GO:0006753) 490 16 .40 + 39.55 2.30E-25 2.56E-22 nucleotide metabolic process (GO:0009117) 481 16 .40 + 40.29 1.72E-25 2.06E-22 small molecule biosynthetic process (GO:0044283) 458 10 .38 + 26.44 5.60E-13 1.75E-10 purine-containing compound metabolic process (GO:0072521) 453 16 .37 + 42.78 6.70E-26 8.72E-23 purine nucleotide metabolic process (GO:0006163) 421 16 .35 + 46.03 2.13E-26 3.02E-23 ribose phosphate metabolic process (GO:0019693) 371 16 .31 + 52.23 2.94E-27 4.59E-24 ribonucleotide metabolic process (GO:0009259) 362 16 .30 + 53.53 2.00E-27 3.48E-24 purine ribonucleotide metabolic process (GO:0009150) 341 16 .28 + 56.83 7.89E-28 1.54E-24 fatty acid metabolic process (GO:0006631) 325 16 .27 + 59.62 3.73E-28 8.31E-25 sulfur compound metabolic process (GO:0006790) 306 16 .25 + 63.33 1.46E-28 3.80E-25 organic acid biosynthetic process (GO:0016053) 278 10 .23 + 43.57 4.34E-15 1.54E-12 carboxylic acid biosynthetic process (GO:0046394) 275 10 .23 + 44.04 3.91E-15 1.42E-12 nucleoside phosphate biosynthetic process (GO:1901293) 269 8 .22 + 36.02 2.11E-11 5.31E-09 nucleotide biosynthetic process (GO:0009165) 267 8 .22 + 36.29 1.99E-11 5.10E-09 purine-containing compound biosynthetic process (GO:0072522) 242 8 .20 + 40.04 9.29E-12 2.42E-09 purine nucleotide biosynthetic process (GO:0006164) 231 8 .19 + 41.94 6.47E-12 1.71E-09 ribose phosphate biosynthetic process (GO:0046390) 217 8 .18 + 44.65 3.99E-12 1.09E-09 ribonucleotide biosynthetic process (GO:0009260) 210 8 .17 + 46.14 3.09E-12 8.93E-10 purine ribonucleotide biosynthetic process (GO:0009152) 195 8 .16 + 49.69 1.74E-12 5.22E-10 monocarboxylic acid biosynthetic process (GO:0072330) 168 10 .14 + 72.09 3.31E-17 1.61E-14 monocarboxylic acid transport (GO:0015718) 151 3 .12 + 24.06 2.58E-04 4.37E-02 sulfur compound biosynthetic process (GO:0044272) 144 8 .12 + 67.28 1.67E-13 5.80E-11 regulation of lipid transport (GO:0032368) 137 3 .11 + 26.52 1.95E-04 3.38E-02 xenobiotic metabolic process (GO:0006805) 125 3 .10 + 29.07 1.49E-04 2.62E-02 fatty acid biosynthetic process (GO:0006633) 118 9 .10 + 92.37 2.24E-16 8.54E-14 purine nucleoside bisphosphate metabolic process (GO:0034032) 117 16 .10 + > 100 6.03E-35 3.14E-31 ribonucleoside bisphosphate metabolic process (GO:0033875) 117 16 .10 + > 100 6.03E-35 2.35E-31 nucleoside bisphosphate metabolic process (GO:0033865) 117 16 .10 + > 100 6.03E-35 1.88E-31 long-chain fatty acid metabolic process (GO:0001676) 111 11 .09 + > 100 2.37E-21 1.68E-18 fatty acid transport (GO:0015908) 92 3 .08 + 39.49 6.16E-05 1.10E-02 acyl-CoA metabolic process (GO:0006637) 90 16 .07 + > 100 1.24E-36 1.94E-32 thioester metabolic process (GO:0035383) 90 16 .07 + > 100 1.24E-36 9.70E-33 regulation of organic acid transport (GO:0032890) 80 3 .07 + 45.42 4.11E-05 7.47E-03 fatty acid derivative metabolic process (GO:1901568) 77 9 .06 + > 100 5.91E-18 3.18E-15 long-chain fatty acid transport (GO:0015909) 55 3 .05 + 66.06 1.40E-05 2.66E-03 purine nucleoside bisphosphate biosynthetic process (GO:0034033) 53 8 .04 + > 100 8.71E-17 3.78E-14 ribonucleoside bisphosphate biosynthetic process (GO:0034030) 53 8 .04 + > 100 8.71E-17 3.67E-14 nucleoside bisphosphate biosynthetic process (GO:0033866) 53 8 .04 + > 100 8.71E-17 3.58E-14 fatty acid derivative biosynthetic process (GO:1901570) 52 8 .04 + > 100 7.57E-17 3.38E-14 acyl-CoA biosynthetic process (GO:0071616) 42 8 .03 + > 100 1.59E-17 8.30E-15 thioester biosynthetic process (GO:0035384) 42 8 .03 + > 100 1.59E-17 8.03E-15 fatty-acyl-CoA metabolic process (GO:0035337) 40 9 .03 + > 100 2.67E-20 1.60E-17 very long-chain fatty acid metabolic process (GO:0000038) 35 6 .03 + > 100 5.15E-13 1.68E-10 regulation of fatty acid transport (GO:2000191) 34 3 .03 + > 100 3.56E-06 7.22E-04 long-chain fatty acid biosynthetic process (GO:0042759) 28 2 .02 + 86.51 2.75E-04 4.61E-02 fatty-acyl-CoA biosynthetic process (GO:0046949) 27 8 .02 + > 100 7.03E-19 3.92E-16 positive regulation of fatty acid transport (GO:2000193) 25 2 .02 + 96.89 2.22E-04 3.81E-02 long-chain fatty-acyl-CoA metabolic process (GO:0035336) 25 7 .02 + > 100 2.07E-16 8.29E-14 long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) 19 7 .02 + > 100 4.06E-17 1.92E-14 short-chain fatty acid metabolic process (GO:0046459) 15 2 .01 + > 100 8.65E-05 1.53E-02 lipid import into cell (GO:0140354) 12 3 .01 + > 100 2.11E-07 4.70E-05 long-chain fatty acid import into cell (GO:0044539) 10 3 .01 + > 100 1.33E-07 3.05E-05 regulation of long-chain fatty acid import into cell (GO:0140212) 8 2 .01 + > 100 2.87E-05 5.27E-03 regulation of long-chain fatty acid import across plasma membrane (GO:0010746) 6 2 .00 + > 100 1.79E-05 3.36E-03 positive regulation of long-chain fatty acid import into cell (GO:0140214) 3 2 .00 + > 100 6.40E-06 1.23E-03 positive regulation of long-chain fatty acid import across plasma membrane (GO:0010747) 2 2 .00 + > 100 3.84E-06 7.59E-04