Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (19) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) hyaluronan metabolic process (GO:0030212) 28 16 .03 + > 100 5.98E-46 8.86E-42 glycosaminoglycan metabolic process (GO:0030203) 77 16 .07 + > 100 2.67E-37 1.98E-33 hyaluronan catabolic process (GO:0030214) 16 12 .01 + > 100 7.62E-36 2.82E-32 aminoglycan metabolic process (GO:0006022) 92 16 .08 + > 100 6.15E-36 3.03E-32 glycosaminoglycan catabolic process (GO:0006027) 26 12 .02 + > 100 4.03E-32 1.20E-28 aminoglycan catabolic process (GO:0006026) 32 12 .03 + > 100 9.41E-31 2.32E-27 carbohydrate derivative catabolic process (GO:1901136) 207 12 .19 + 62.79 3.68E-20 7.80E-17 carbohydrate derivative metabolic process (GO:1901135) 895 16 .83 + 19.36 1.23E-19 2.28E-16 hyaluronan biosynthetic process (GO:0030213) 6 5 .01 + > 100 2.27E-15 3.73E-12 glycosaminoglycan biosynthetic process (GO:0006024) 40 6 .04 + > 100 9.70E-13 1.44E-09 carbohydrate metabolic process (GO:0005975) 442 10 .41 + 24.51 1.47E-12 1.98E-09 aminoglycan biosynthetic process (GO:0006023) 48 6 .04 + > 100 3.09E-12 3.81E-09 macromolecule catabolic process (GO:0009057) 1057 12 .98 + 12.30 1.14E-11 1.30E-08 proteoglycan catabolic process (GO:0030167) 17 4 .02 + > 100 1.23E-09 1.30E-06 chondroitin sulfate proteoglycan catabolic process (GO:0030207) 4 3 .00 + > 100 2.67E-09 2.63E-06 macromolecule metabolic process (GO:0043170) 5404 17 4.99 + 3.41 1.28E-08 1.18E-05 catabolic process (GO:0009056) 2040 12 1.88 + 6.37 2.26E-08 1.97E-05 response to antibiotic (GO:0046677) 37 4 .03 + > 100 3.36E-08 2.62E-05 glycoprotein catabolic process (GO:0006516) 37 4 .03 + > 100 3.36E-08 2.77E-05 cellular response to UV-B (GO:0071493) 12 3 .01 + > 100 1.46E-07 1.08E-04 skeletal system development (GO:0001501) 514 7 .47 + 14.75 2.26E-07 1.59E-04 cellular response to interleukin-1 (GO:0071347) 76 4 .07 + 57.01 6.38E-07 4.30E-04 response to UV-B (GO:0010224) 21 3 .02 + > 100 8.78E-07 5.66E-04 cellular response to platelet-derived growth factor stimulus (GO:0036120) 23 3 .02 + > 100 1.17E-06 7.21E-04 polysaccharide biosynthetic process (GO:0000271) 25 3 .02 + > 100 1.51E-06 8.98E-04 response to platelet-derived growth factor (GO:0036119) 26 3 .02 + > 100 1.71E-06 9.75E-04 cellular response to pH (GO:0071467) 27 3 .02 + > 100 1.92E-06 1.06E-03 response to interleukin-1 (GO:0070555) 101 4 .09 + 42.90 2.00E-06 1.06E-03 proteoglycan metabolic process (GO:0006029) 106 4 .10 + 40.87 2.43E-06 1.09E-03 regulation of hyaluranon cable assembly (GO:1900104) 3 2 .00 + > 100 2.42E-06 1.12E-03 positive regulation of hyaluranon cable assembly (GO:1900106) 3 2 .00 + > 100 2.42E-06 1.16E-03 chondroitin sulfate proteoglycan metabolic process (GO:0050654) 30 3 .03 + > 100 2.67E-06 1.16E-03 regulation of monocyte aggregation (GO:1900623) 3 2 .00 + > 100 2.42E-06 1.20E-03 positive regulation of monocyte aggregation (GO:1900625) 3 2 .00 + > 100 2.42E-06 1.24E-03 extracellular matrix assembly (GO:0085029) 31 3 .03 + > 100 2.95E-06 1.25E-03 metabolic process (GO:0008152) 7642 17 7.06 + 2.41 3.47E-06 1.43E-03 dermatan sulfate proteoglycan catabolic process (GO:0030209) 4 2 .00 + > 100 4.84E-06 1.94E-03 response to pH (GO:0009268) 40 3 .04 + 81.24 6.45E-06 2.51E-03 carbohydrate derivative biosynthetic process (GO:1901137) 556 6 .51 + 11.69 7.61E-06 2.89E-03 renal water absorption (GO:0070295) 5 2 .00 + > 100 8.06E-06 2.99E-03 cellular response to tumor necrosis factor (GO:0071356) 149 4 .14 + 29.08 9.40E-06 3.40E-03 cellular response to environmental stimulus (GO:0104004) 332 5 .31 + 16.31 1.02E-05 3.53E-03 sulfur compound catabolic process (GO:0044273) 47 3 .04 + 69.14 1.05E-05 3.55E-03 cellular response to abiotic stimulus (GO:0071214) 332 5 .31 + 16.31 1.02E-05 3.61E-03 response to tumor necrosis factor (GO:0034612) 171 4 .16 + 25.34 1.62E-05 5.33E-03 renal water transport (GO:0003097) 7 2 .01 + > 100 1.69E-05 5.45E-03 cartilage development (GO:0051216) 179 4 .17 + 24.20 1.94E-05 6.11E-03 ganglioside catabolic process (GO:0006689) 8 2 .01 + > 100 2.25E-05 6.96E-03 negative regulation of fibroblast migration (GO:0010764) 11 2 .01 + > 100 4.42E-05 1.28E-02 polysaccharide metabolic process (GO:0005976) 75 3 .07 + 43.33 4.32E-05 1.31E-02 penetration of zona pellucida (GO:0007341) 11 2 .01 + > 100 4.42E-05 1.31E-02 positive regulation of urine volume (GO:0035810) 12 2 .01 + > 100 5.30E-05 1.51E-02 cellular response to growth factor stimulus (GO:0071363) 478 5 .44 + 11.33 5.88E-05 1.64E-02 dermatan sulfate proteoglycan metabolic process (GO:0050655) 13 2 .01 + > 100 6.26E-05 1.72E-02 connective tissue development (GO:0061448) 244 4 .23 + 17.76 6.50E-05 1.75E-02 cellular response to fibroblast growth factor stimulus (GO:0044344) 87 3 .08 + 37.35 6.73E-05 1.78E-02 cellular response to UV (GO:0034644) 90 3 .08 + 36.11 7.45E-05 1.94E-02 response to growth factor (GO:0070848) 509 5 .47 + 10.64 7.92E-05 2.02E-02 response to fibroblast growth factor (GO:0071774) 95 3 .09 + 34.20 8.75E-05 2.20E-02 glycosphingolipid catabolic process (GO:0046479) 18 2 .02 + > 100 1.22E-04 3.02E-02 cellular response to acidic pH (GO:0071468) 19 2 .02 + > 100 1.37E-04 3.32E-02 cellular response to endogenous stimulus (GO:0071495) 936 6 .86 + 6.94 1.42E-04 3.39E-02 cellular response to light stimulus (GO:0071482) 114 3 .11 + 28.50 1.50E-04 3.54E-02 carbohydrate biosynthetic process (GO:0016051) 116 3 .11 + 28.01 1.58E-04 3.66E-02 ceramide catabolic process (GO:0046514) 21 2 .02 + > 100 1.68E-04 3.71E-02 regulation of urine volume (GO:0035809) 21 2 .02 + > 100 1.68E-04 3.77E-02 glycolipid catabolic process (GO:0019377) 21 2 .02 + > 100 1.68E-04 3.83E-02 N-glycan processing (GO:0006491) 22 2 .02 + 98.47 1.84E-04 4.02E-02 renal water homeostasis (GO:0003091) 23 2 .02 + 94.19 2.02E-04 4.34E-02