BLASTP 2.10.0+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Stephen F. Altschul, John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. RID: 9XZF51WY014 Database: Non-redundant UniProtKB/SwissProt sequences 473,509 sequences; 178,961,532 total letters Query= P25321.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Cricetulus griseus] Length=351 Score E Max Sequences producing significant alignments: (Bits) Value Ident P25321.2 RecName: Full=cAMP-dependent protein kinase catalytic... 729 0.0 100% P27791.2 RecName: Full=cAMP-dependent protein kinase catalytic... 724 0.0 99% P05132.3 RecName: Full=cAMP-dependent protein kinase catalytic... 720 0.0 99% P17612.2 RecName: Full=cAMP-dependent protein kinase catalytic... 719 0.0 98% Q9MZD9.3 RecName: Full=cAMP-dependent protein kinase catalytic... 716 0.0 98% P00517.3 RecName: Full=cAMP-dependent protein kinase catalytic... 716 0.0 98% P36887.4 RecName: Full=cAMP-dependent protein kinase catalytic... 714 0.0 97% Q8MJ44.3 RecName: Full=cAMP-dependent protein kinase catalytic... 709 0.0 97% P05383.3 RecName: Full=cAMP-dependent protein kinase catalytic... 677 0.0 93% P22694.2 RecName: Full=cAMP-dependent protein kinase catalytic... 676 0.0 92% P05131.2 RecName: Full=cAMP-dependent protein kinase catalytic... 676 0.0 92% P68180.2 RecName: Full=cAMP-dependent protein kinase catalytic... 669 0.0 92% P22612.3 RecName: Full=cAMP-dependent protein kinase catalytic... 619 0.0 81% P12370.3 RecName: Full=cAMP-dependent protein kinase catalytic... 615 0.0 82% P21137.3 RecName: Full=cAMP-dependent protein kinase catalytic... 562 0.0 76% A8XW88.1 RecName: Full=cAMP-dependent protein kinase catalytic... 559 0.0 75% O62846.3 RecName: Full=cAMP-dependent protein kinase catalytic... 378 3e-132 84% P51817.1 RecName: Full=cAMP-dependent protein kinase catalytic... 374 4e-128 55% P16912.2 RecName: Full=cAMP-dependent protein kinase catalytic... 373 7e-125 56% Q922R0.1 RecName: Full=cAMP-dependent protein kinase catalytic... 363 6e-124 50% P34099.2 RecName: Full=cAMP-dependent protein kinase catalytic... 369 2e-122 55% P06245.2 RecName: Full=cAMP-dependent protein kinase type 2; S... 357 4e-121 53% Q7JP68.1 RecName: Full=cAMP-dependent protein kinase, catalyti... 353 1e-119 51% P06244.3 RecName: Full=cAMP-dependent protein kinase type 1; S... 353 2e-119 48% P21901.1 RecName: Full=Spermatozoon-associated protein kinase;... 349 2e-118 50% A8XJQ6.2 RecName: Full=cAMP-dependent protein kinase, catalyti... 346 7e-117 48% P49673.1 RecName: Full=cAMP-dependent protein kinase catalytic... 342 7e-116 53% P05986.2 RecName: Full=cAMP-dependent protein kinase type 3; S... 343 1e-115 51% P16911.2 RecName: Full=cAMP-dependent protein kinase catalytic... 330 5e-111 48% P40376.1 RecName: Full=cAMP-dependent protein kinase catalytic... 335 5e-111 46% P28178.2 RecName: Full=Protein kinase 2; Short=PK2 [Dictyostel... 293 1e-94 45% Q2PJ68.1 RecName: Full=Serine/threonine-protein kinase sgk-1; ... 288 3e-93 48% P54644.1 RecName: Full=RAC family serine/threonine-protein kin... 285 3e-92 42% O43930.1 PUTATIVE PSEUDOGENE: RecName: Full=Putative serine/th... 278 8e-92 53% A8XNJ6.3 RecName: Full=Serine/threonine-protein kinase sgk-1; ... 284 2e-91 47% Q6GPN6.1 RecName: Full=Serine/threonine-protein kinase Sgk1-A;... 281 7e-91 41% Q5BKK4.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 280 9e-91 41% Q13237.1 RecName: Full=cGMP-dependent protein kinase 2; Short=... 289 3e-90 47% P00516.2 RecName: Full=cGMP-dependent protein kinase 1; Short=... 286 4e-90 46% Q13976.3 RecName: Full=cGMP-dependent protein kinase 1; Short=... 286 4e-90 46% P0C605.1 RecName: Full=cGMP-dependent protein kinase 1; Short=... 286 4e-90 46% O77676.3 RecName: Full=cGMP-dependent protein kinase 1; Short=... 286 5e-90 46% Q17941.2 RecName: Full=Serine/threonine-protein kinase akt-1; ... 282 6e-90 43% Q6GLY8.1 RecName: Full=Serine/threonine-protein kinase Sgk1-B;... 279 6e-90 40% Q64595.1 RecName: Full=cGMP-dependent protein kinase 2; Short=... 287 1e-89 46% Q61410.1 RecName: Full=cGMP-dependent protein kinase 2; Short=... 287 2e-89 46% Q9P7J8.1 RecName: Full=Serine/threonine-protein kinase gad8 [S... 282 2e-89 45% Q7ZTW4.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 277 3e-89 43% Q8R4U9.2 RecName: Full=Serine/threonine-protein kinase Sgk2; A... 274 5e-89 44% Q9QZS5.1 RecName: Full=Serine/threonine-protein kinase Sgk2; A... 274 7e-89 44% Q6U1I9.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 275 1e-88 43% Q9XT18.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 275 2e-88 43% P12688.2 RecName: Full=Serine/threonine-protein kinase YPK1; A... 282 2e-88 45% Q9HBY8.1 RecName: Full=Serine/threonine-protein kinase Sgk2; A... 274 4e-88 44% A7MB74.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 274 6e-88 43% Q5Q0U5.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 274 6e-88 43% Q9WVC6.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 273 1e-87 43% Q7ZX15.1 RecName: Full=RAC-beta serine/threonine-protein kinas... 273 7e-87 44% O00141.2 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 270 1e-86 43% Q06226.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 270 2e-86 43% P34102.2 RecName: Full=Protein kinase 3; Short=PK3 [Dictyostel... 281 2e-86 45% P31751.2 RecName: Full=RAC-beta serine/threonine-protein kinas... 271 2e-86 43% Q4R633.1 RecName: Full=Serine/threonine-protein kinase Sgk1; A... 268 8e-86 43% P18961.1 RecName: Full=Serine/threonine-protein kinase YPK2/YK... 275 8e-86 45% P47197.1 RecName: Full=RAC-beta serine/threonine-protein kinas... 269 2e-85 40% P47196.1 RecName: Full=RAC-alpha serine/threonine-protein kina... 269 2e-85 42% Q6IP76.1 RecName: Full=RAC-beta serine/threonine-protein kinas... 269 2e-85 44% Q01314.2 RecName: Full=RAC-alpha serine/threonine-protein kina... 269 2e-85 45% P31750.2 RecName: Full=RAC-alpha serine/threonine-protein kina... 269 2e-85 42% P31748.1 RecName: Full=AKT kinase-transforming protein [AKT8 m... 269 3e-85 42% Q60823.1 RecName: Full=RAC-beta serine/threonine-protein kinas... 268 4e-85 44% Q9Y243.1 RecName: Full=RAC-gamma serine/threonine-protein kina... 268 4e-85 43% P34103.2 RecName: Full=Protein kinase 4 [Dictyostelium discoid... 280 4e-85 44% Q9WUA6.1 RecName: Full=RAC-gamma serine/threonine-protein kina... 268 4e-85 43% Q63484.2 RecName: Full=RAC-gamma serine/threonine-protein kina... 267 9e-85 43% P31749.2 RecName: Full=RAC-alpha serine/threonine-protein kina... 266 2e-84 42% Q98TY9.1 RecName: Full=RAC-alpha serine/threonine-protein kina... 266 2e-84 42% Q9XTG7.1 RecName: Full=Serine/threonine-protein kinase akt-2; ... 266 1e-83 42% P11792.3 RecName: Full=Serine/threonine-protein kinase SCH9 [S... 271 7e-83 47% Q8INB9.3 RecName: Full=RAC serine/threonine-protein kinase; Sh... 262 2e-81 42% Q9NAH6.2 RecName: Full=Ribosomal protein S6 kinase beta [Caeno... 260 3e-81 43% Q8MYF1.1 RecName: Full=Probable serine/threonine-protein kinas... 255 2e-80 42% Q03042.2 RecName: Full=cGMP-dependent protein kinase, isozyme ... 263 2e-80 42% Q54IF2.1 RecName: Full=Probable serine/threonine-protein kinas... 259 4e-80 43% Q8R4V0.2 RecName: Full=Serine/threonine-protein kinase Sgk3; A... 255 5e-80 42% P50530.2 RecName: Full=Serine/threonine-protein kinase sck1 [S... 259 1e-79 44% Q9ERE3.1 RecName: Full=Serine/threonine-protein kinase Sgk3; A... 254 1e-79 42% Q5R7A7.1 RecName: Full=Serine/threonine-protein kinase Sgk3; A... 252 7e-79 42% Q39030.2 RecName: Full=Serine/threonine-protein kinase AtPK2/A... 249 4e-78 39% P24723.4 RecName: Full=Protein kinase C eta type; AltName: Ful... 254 7e-78 42% P32023.3 RecName: Full=cGMP-dependent protein kinase, isozyme ... 259 1e-77 43% Q64617.1 RecName: Full=Protein kinase C eta type; AltName: Ful... 253 2e-77 42% P23298.2 RecName: Full=Protein kinase C eta type; AltName: Ful... 252 8e-77 42% Q9Z1M4.1 RecName: Full=Ribosomal protein S6 kinase beta-2; Sho... 246 1e-76 41% Q03043.3 RecName: Full=cGMP-dependent protein kinase, isozyme ... 257 2e-76 43% P42818.1 RecName: Full=Serine/threonine-protein kinase AtPK1/A... 245 2e-76 40% P34885.2 RecName: Full=Protein kinase C-like 1B; Short=PKC1B [... 251 2e-76 43% Q9UBS0.2 RecName: Full=Ribosomal protein S6 kinase beta-2; Sho... 245 3e-76 40% A8X6H1.2 RecName: Full=cGMP-dependent protein kinase egl-4; Al... 251 5e-76 41% O76360.2 RecName: Full=cGMP-dependent protein kinase egl-4; Al... 251 8e-76 41% ALIGNMENTS >P25321.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Cricetulus griseus] Length=351 Score = 729 bits (1881), Expect = 0.0, Method: Compositional matrix adjust. Identities = 351/351 (100%), Positives = 351/351 (100%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 >P27791.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Rattus norvegicus] Length=351 Score = 724 bits (1870), Expect = 0.0, Method: Compositional matrix adjust. Identities = 348/351 (99%), Positives = 350/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWE PSQNTAQLDHFDRIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWEDPSQNTAQLDHFDRIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKE+GNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 >P05132.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Mus musculus] Length=351 Score = 720 bits (1859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/351 (99%), Positives = 349/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWE+PSQNTAQLD FDRIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWETPSQNTAQLDQFDRIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKE+GNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHKESGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYV GGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVAGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 >P17612.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Homo sapiens] Length=351 Score = 719 bits (1855), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/351 (98%), Positives = 349/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWESP+QNTA LD F+RIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEF+EF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351 >Q9MZD9.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Ovis aries] Length=351 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/351 (98%), Positives = 348/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWE+P+QNTA LD F+RIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKH ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHTETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEF+EF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351 >P00517.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Bos taurus] Length=351 Score = 716 bits (1847), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/351 (98%), Positives = 348/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWE+P+QNTA LD F+RIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKH ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 61 VKHMETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEF+EF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351 >P36887.4 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Sus scrofa] Length=351 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/351 (97%), Positives = 349/351 (99%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAAAKKGSEQESVKEFLAKAKE+FLKKWE+P+QNTA LD F+RIKTLGTGSFGRVML Sbjct 1 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKETGNH+AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLE+SFKDNSNLYMV Sbjct 61 VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEYSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEF+EF Sbjct 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 351 >Q8MJ44.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit alpha; Short=PKA C-alpha [Canis lupus familiaris] Length=350 Score = 709 bits (1829), Expect = 0.0, Method: Compositional matrix adjust. Identities = 342/351 (97%), Positives = 347/351 (99%), Gaps = 1/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAA KKGSEQESVKEFLAKAKE+FLKKWE+P+QNTA LD F+RIKTLGTGSFGRVML Sbjct 1 MGNAAA-KKGSEQESVKEFLAKAKEDFLKKWENPAQNTAHLDQFERIKTLGTGSFGRVML 59 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHKETGNH+AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV Sbjct 60 VKHKETGNHFAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 119 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY Sbjct 120 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 179 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 180 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 239 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT Sbjct 240 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 299 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEF EF Sbjct 300 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFCEF 350 >P05383.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Sus scrofa] Length=351 Score = 677 bits (1747), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/351 (93%), Positives = 336/351 (96%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAA AKKGSE ESVKEFLAKAKE+FLKKWE+P+ N A L+ F+R KTLGTGSFGRVML Sbjct 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHK T +YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV+LEFSFKDNSNLYMV Sbjct 61 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEFSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID QGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKF+G GDTSNFDDYEEE+IRVSI EKCGKEF EF Sbjct 301 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF 351 >P22694.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Homo sapiens] Length=351 Score = 676 bits (1745), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/351 (92%), Positives = 336/351 (96%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAA AKKGSE ESVKEFLAKAKE+FLKKWE+P+QN A L+ F+R KTLGTGSFGRVML Sbjct 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHK T +YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV+LE++FKDNSNLYMV Sbjct 61 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID QGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKF+G GDTSNFDDYEEE+IRVSI EKC KEF EF Sbjct 301 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 351 >P05131.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Bos taurus] Length=351 Score = 676 bits (1743), Expect = 0.0, Method: Compositional matrix adjust. Identities = 324/351 (92%), Positives = 336/351 (96%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAA AKKGSE ESVKEFLAKAKE+FLKKWE+P+ N A L+ F+R KTLGTGSFGRVML Sbjct 1 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPAPNNAGLEDFERKKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHK T +YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV+LE++FKDNSNLYMV Sbjct 61 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID QGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKF+G GDTSNFDDYEEE+IRVSI EKCGKEF EF Sbjct 301 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCGKEFCEF 351 >P68180.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Cricetulus griseus] P68181.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Mus musculus] P68182.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit beta; Short=PKA C-beta [Rattus norvegicus] Length=351 Score = 669 bits (1726), Expect = 0.0, Method: Compositional matrix adjust. Identities = 322/351 (92%), Positives = 333/351 (95%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGN A AKKGSE ESVKEFLAKAKE+FL+KWE+P + A L+ F+R KTLGTGSFGRVML Sbjct 1 MGNTAIAKKGSEVESVKEFLAKAKEDFLRKWENPPPSNAGLEDFERKKTLGTGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VKHK T +YAMKILDKQKVVKLKQIEHTLNEKRILQAV FPFLV+LE+SFKDNSNLYMV Sbjct 61 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVEFPFLVRLEYSFKDNSNLYMV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID QGY Sbjct 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF Sbjct 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGV+DIK HKWFAT Sbjct 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 TDWIAIYQRKVEAPFIPKF+G GDTSNFDDYEEEEIRVSI EKCGKEF EF Sbjct 301 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEEIRVSITEKCGKEFCEF 351 >P22612.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit gamma; Short=PKA C-gamma [Homo sapiens] Length=351 Score = 619 bits (1595), Expect = 0.0, Method: Compositional matrix adjust. Identities = 286/351 (81%), Positives = 322/351 (92%), Gaps = 0/351 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNA A K ++ESV EFLAKA+ +FL +W +P+QNTA D F+R++TLG GSFGRVML Sbjct 1 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML 60 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 V+H+ETG HYAMKIL+KQKVVK+KQ+EH LNEKRILQA++FPFLVKL+FSFKDNS LY+V Sbjct 61 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV 120 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFS L+R+GRFSEPHA FYAAQ+VL +YLHSLDLI+RDLKPENLLIDQQGY Sbjct 121 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY 180 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 +QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA G+PPF+ Sbjct 181 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY 240 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 ADQPIQIYEKIVSG+VRFPS SSDLK LLR+LLQVDLTKRFGNL+NGV DIKNHKWFAT Sbjct 241 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT 300 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 T WIAIY++KVEAPFIPK+ GPGD SNFDDYEEEE+R+SINEKC KEF+EF Sbjct 301 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 351 >P12370.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit 1; Short=PKA C; AltName: Full=Protein kinase DC0 [Drosophila melanogaster] Length=353 Score = 615 bits (1587), Expect = 0.0, Method: Compositional matrix adjust. Identities = 291/353 (82%), Positives = 316/353 (90%), Gaps = 2/353 (1%) Query 1 MGNAAAA--KKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRV 58 MGN A KK E+VKEFL +AKEEF KW NTA LD F+RIKTLGTGSFGRV Sbjct 1 MGNNATTSNKKVDAAETVKEFLEQAKEEFEDKWRRNPTNTAALDDFERIKTLGTGSFGRV 60 Query 59 MLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLY 118 M+V+HK T ++YAMKILDKQKVVKLKQ+EHTLNEKRILQA+ FPFLV L + FKDNSNLY Sbjct 61 MIVQHKPTKDYYAMKILDKQKVVKLKQVEHTLNEKRILQAIQFPFLVSLRYHFKDNSNLY 120 Query 119 MVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQ 178 MV+EYVPGGEMFSHLR++GRFSEPH+RFYAAQIVL FEYLH LDLIYRDLKPENLLID Q Sbjct 121 MVLEYVPGGEMFSHLRKVGRFSEPHSRFYAAQIVLAFEYLHYLDLIYRDLKPENLLIDSQ 180 Query 179 GYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPP 238 GY++VTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVL+YEMAAGYPP Sbjct 181 GYLKVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLVYEMAAGYPP 240 Query 239 FFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWF 298 FFADQPIQIYEKIVSGKVRFPSHF SDLKDLLRNLLQVDLTKR+GNLK GVNDIKN KWF Sbjct 241 FFADQPIQIYEKIVSGKVRFPSHFGSDLKDLLRNLLQVDLTKRYGNLKAGVNDIKNQKWF 300 Query 299 ATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 A+TDWIAI+Q+K+EAPFIP+ KGPGDTSNFDDYEEE +R+S EKC KEF EF Sbjct 301 ASTDWIAIFQKKIEAPFIPRCKGPGDTSNFDDYEEEALRISSTEKCAKEFAEF 353 >P21137.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit; Short=PKA C [Caenorhabditis elegans] Length=404 Score = 562 bits (1449), Expect = 0.0, Method: Compositional matrix adjust. Identities = 268/354 (76%), Positives = 304/354 (86%), Gaps = 16/354 (5%) Query 14 ESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMK 73 E KEFL KA+E+F ++WE+P+QNTA LD FDRIKTLGTGSFGRVMLVKHK++GN+YAMK Sbjct 51 EDFKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLVKHKQSGNYYAMK 110 Query 74 ILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHL 133 ILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV + FSFKDNSNLYMV+E++ GGEMFSHL Sbjct 111 ILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVLEFISGGEMFSHL 170 Query 134 RRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK 193 RRIGRFSEPH+RFYAAQIVL FEYLHSLDLIYRDLKPENLLID GY+++TDFGFAKRVK Sbjct 171 RRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYLKITDFGFAKRVK 230 Query 194 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 253 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS Sbjct 231 GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVS 290 Query 254 GKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA 313 GKV+FPSHFS++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +TDWIAIYQ+K+ Sbjct 291 GKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGSTDWIAIYQKKITP 350 Query 314 P--------------FIPKFKGPGDTSNFDDYEEE--EIRVSINEKCGKEFTEF 351 P P+ GP DT +F + +E E ++ + + F EF Sbjct 351 PSFSKGESNGRLFEALYPRVDGPADTRHFVEEVQEPTEFVIAATPQLEELFVEF 404 >A8XW88.1 RecName: Full=cAMP-dependent protein kinase catalytic subunit; Short=PKA C [Caenorhabditis briggsae] Length=374 Score = 559 bits (1440), Expect = 0.0, Method: Compositional matrix adjust. Identities = 266/357 (75%), Positives = 303/357 (85%), Gaps = 15/357 (4%) Query 2 GNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLV 61 + ++K S+KEFL KA+E+F ++WE+P+QNTA LD FDRIKTLGTGSFGRVMLV Sbjct 10 SDEGSSKDNKSAASLKEFLDKAREDFKQRWENPAQNTACLDDFDRIKTLGTGSFGRVMLV 69 Query 62 KHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVM 121 KHK++GN+YAMKILDKQKVVKLKQ+EHTLNEKRILQA++FPFLV + FSFKDNSNLYMV+ Sbjct 70 KHKQSGNYYAMKILDKQKVVKLKQVEHTLNEKRILQAIDFPFLVNMTFSFKDNSNLYMVL 129 Query 122 EYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYI 181 E++ GGEMFSHLRRIGRFSEPH+RFYAAQIVL FEYLHSLDLIYRDLKPENLLID GY+ Sbjct 130 EFISGGEMFSHLRRIGRFSEPHSRFYAAQIVLAFEYLHSLDLIYRDLKPENLLIDSTGYL 189 Query 182 QVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA 241 ++TDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA Sbjct 190 KITDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFA 249 Query 242 DQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATT 301 DQPIQI EKIVSGKV+FPSHFS++LKDLL+NLLQVDLTKR+GNLKNGV DIKNHKWF +T Sbjct 250 DQPIQI-EKIVSGKVKFPSHFSNELKDLLKNLLQVDLTKRYGNLKNGVADIKNHKWFGST 308 Query 302 DWIAIYQRKVEAP--------------FIPKFKGPGDTSNFDDYEEEEIRVSINEKC 344 DWIAIYQRK++ P + GP DT +F + +E + I C Sbjct 309 DWIAIYQRKIKPPSFSNGEPKGRLFEALYARVDGPADTRHFVEEVQEPTQFVIASTC 365 >O62846.3 RecName: Full=cAMP-dependent protein kinase catalytic subunit gamma; Short=PKA C-gamma [Macaca mulatta] Length=209 Score = 378 bits (971), Expect = 3e-132, Method: Compositional matrix adjust. Identities = 176/210 (84%), Positives = 198/210 (94%), Gaps = 1/210 (0%) Query 1 MGNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVML 60 MGNAAA KK +EQE+V EFLAKA+ +FL +W +P+QNTA D F+R+KTLGTGS+GRVML Sbjct 1 MGNAAA-KKDTEQETVNEFLAKARGDFLYRWGNPAQNTASSDQFERLKTLGTGSYGRVML 59 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 V+H+ETGNHYAMKILDKQKVV+LKQ+EHTLNEKRILQA+NFPFLVKL+FSFKDNSNLY+V Sbjct 60 VRHRETGNHYAMKILDKQKVVRLKQVEHTLNEKRILQAINFPFLVKLQFSFKDNSNLYLV 119 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 MEYVPGGEMFSHLRR+GRFSEP A FYAAQ+VL F+YLHSLDLI+RDLKPENLLIDQQGY Sbjct 120 MEYVPGGEMFSHLRRVGRFSEPQACFYAAQVVLAFQYLHSLDLIHRDLKPENLLIDQQGY 179 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEI 210 +QVTDFGFAKRVKGRTWTLCGTPEYLAPEI Sbjct 180 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEI 209 >P51817.1 RecName: Full=cAMP-dependent protein kinase catalytic subunit PRKX; Short=PrKX; Short=Protein kinase X; Short=Protein kinase X-linked; Short=Serine/threonine-protein kinase PRKX; AltName: Full=Protein kinase PKX1 [Homo sapiens] Length=358 Score = 374 bits (959), Expect = 4e-128, Method: Compositional matrix adjust. Identities = 166/303 (55%), Positives = 228/303 (75%), Gaps = 0/303 (0%) Query 33 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 SP L FD + T+GTG+FGRV LVK K + +A+K++ V++LKQ +H NE Sbjct 38 SPEPPVYSLQDFDTLATVGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRLKQEQHVHNE 97 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 K +L+ V+ PFL++L +++ D LYM+MEYVPGGE+FS+LR GRFS FY+A+I+ Sbjct 98 KSVLKEVSHPFLIRLFWTWHDERFLYMLMEYVPGGELFSYLRNRGRFSSTTGLFYSAEII 157 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIIL 212 EYLHS +++YRDLKPEN+L+D+ G+I++TDFGFAK++ RTWTLCGTPEYLAPE+I Sbjct 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217 Query 213 SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRN 272 SKG+ +AVDWWALG+LI+EM +G+PPFF D P IY+KI++GK+ FP H +KDL++ Sbjct 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKIDFPRHLDFHVKDLIKK 277 Query 273 LLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYE 332 LL VD T+R GN+KNG ND+K+H+WF + DW A+ QRK++ P +PK G GDTSNF+ Y Sbjct 278 LLVVDRTRRLGNMKNGANDVKHHRWFRSVDWEAVPQRKLKPPIVPKIAGDGDTSNFETYP 337 Query 333 EEE 335 E + Sbjct 338 END 340 >P16912.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit 3; AltName: Full=Protein kinase DC2 [Drosophila melanogaster] Length=583 Score = 373 bits (958), Expect = 7e-125, Method: Compositional matrix adjust. Identities = 166/296 (56%), Positives = 224/296 (76%), Gaps = 0/296 (0%) Query 40 QLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 LD + IKT+GTG+FGRV L + + + + AMKIL +V++LKQIEH NE+ IL+ + Sbjct 270 HLDDYQIIKTVGTGTFGRVCLCRDRISEKYCAMKILAMTEVIRLKQIEHVKNERNILREI 329 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 PF++ LE+S KD+SNLYM+ +YV GGE+F++LR G+F+ + FYAA+IV EYLH Sbjct 330 RHPFVISLEWSTKDDSNLYMIFDYVCGGELFTYLRNAGKFTSQTSNFYAAEIVSALEYLH 389 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKA 219 SL ++YRDLKPENLLI++ G++++TDFGFAK+++ RTWTLCGTPEY+APEII SKG+NKA Sbjct 390 SLQIVYRDLKPENLLINRDGHLKITDFGFAKKLRDRTWTLCGTPEYIAPEIIQSKGHNKA 449 Query 220 VDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLT 279 VDWWALGVLIYEM GYPPF+ +QP IYEKI+SGK+ + H KDL++ LL D T Sbjct 450 VDWWALGVLIYEMLVGYPPFYDEQPFGIYEKILSGKIEWERHMDPIAKDLIKKLLVNDRT 509 Query 280 KRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEE 335 KR GN+KNG +D+K H+WF +W +Y +K++ P +P GDT NFDDY E++ Sbjct 510 KRLGNMKNGADDVKRHRWFKHLNWNDVYSKKLKPPILPDVHHDGDTKNFDDYPEKD 565 >Q922R0.1 RecName: Full=cAMP-dependent protein kinase catalytic subunit PRKX; Short=PrKX; Short=Protein kinase X; Short=Protein kinase X-linked; Short=Serine/threonine-protein kinase PRKX; AltName: Full=PKA-related protein kinase [Mus musculus] Length=355 Score = 363 bits (931), Expect = 6e-124, Method: Compositional matrix adjust. Identities = 175/353 (50%), Positives = 243/353 (69%), Gaps = 5/353 (1%) Query 2 GNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQ-LDHFDRIKTLGTGSFGRVML 60 AAA K + + VK ++ + K + SQ L +D I T+GTG+FGRV L Sbjct 5 AGAAATVKDPDHDPVKTKVSAPAAD--PKPRTSSQKAGHSLQDWDTIATVGTGTFGRVNL 62 Query 61 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 120 VK K + A+KI+ V++LKQ +H NEK +L+ +N PFL+KL ++ DN LYM+ Sbjct 63 VKEKTGRQYCALKIMSIPDVIRLKQEQHVQNEKAVLKEINHPFLIKLLWTGHDNRFLYML 122 Query 121 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 180 ME+VPGGE+F++LR GRFS + FYA +IV EYLHS +++YRDLKPEN+L+D++G+ Sbjct 123 MEFVPGGELFTYLRNRGRFSSVASVFYATEIVCAIEYLHSKEIVYRDLKPENILLDREGH 182 Query 181 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 240 I++TDFGFAK++ RTWTLCGTPEYLAPE+I SKG+ +AVDWWALG+LI+EM +G+PPFF Sbjct 183 IKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQSKGHGRAVDWWALGILIFEMLSGFPPFF 242 Query 241 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 300 D P IY+KI++ K+ FP KDL++ LL VD T+R GN+KNG DIK H+WF Sbjct 243 DDNPFGIYQKILACKIDFPRQLDFTSKDLIKKLLVVDRTRRLGNMKNGAEDIKRHRWFRG 302 Query 301 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEI--RVSINEKCGKEFTEF 351 +W ++ QRK++ P +PK G GD SNF+ Y E E+ S+++K + F F Sbjct 303 VEWESVPQRKLKPPIVPKLSGDGDISNFETYPESELDKTPSVSDKDLETFKNF 355 >P34099.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit; AltName: Full=Dd GPK2; AltName: Full=DdPK3 [Dictyostelium discoideum] Length=648 Score = 369 bits (947), Expect = 2e-122, Method: Compositional matrix adjust. Identities = 168/303 (55%), Positives = 229/303 (76%), Gaps = 0/303 (0%) Query 34 PSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEK 93 P +L F +I+ +GTG+FG+V L+++ + G +YAMK L+K VV+LKQ+EH +EK Sbjct 326 PVNARERLKEFKQIRVIGTGTFGKVYLIQNTKDGCYYAMKCLNKAYVVQLKQVEHLNSEK 385 Query 94 RILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVL 153 IL +++ PF+V L +F+D LY++ EYV GGE+F+HLR+ +FS A+FYAA+IVL Sbjct 386 SILSSIHHPFIVNLYQAFQDEKKLYLLFEYVAGGEVFTHLRKSMKFSNSTAKFYAAEIVL 445 Query 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILS 213 E+LH +++YRDLKPENLLID QG+I++TDFGFAKRV+ RT+TLCGTPEYLAPEII S Sbjct 446 ALEFLHKQNIVYRDLKPENLLIDNQGHIKITDFGFAKRVEDRTFTLCGTPEYLAPEIIQS 505 Query 214 KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 273 KG+ KAVDWWALG+LI+EM AGYPPF+ D IY KI++G++ FP F D KDL++ L Sbjct 506 KGHGKAVDWWALGILIFEMLAGYPPFYDDDTFAIYNKILAGRITFPLGFDVDAKDLIKRL 565 Query 274 LQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 333 L D T+R G LK+G D+KNH+WF+ +W +YQR+ PFIPK + GD+SNF+ Y+E Sbjct 566 LTADRTRRLGALKDGALDVKNHRWFSDINWERLYQRRDNGPFIPKIQHQGDSSNFEMYDE 625 Query 334 EEI 336 EE+ Sbjct 626 EEM 628 >P06245.2 RecName: Full=cAMP-dependent protein kinase type 2; Short=PKA 2 [Saccharomyces cerevisiae S288C] Length=380 Score = 357 bits (915), Expect = 4e-121, Method: Compositional matrix adjust. Identities = 163/308 (53%), Positives = 226/308 (73%), Gaps = 1/308 (0%) Query 35 SQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKR 94 S+ L F ++TLGTGSFGRV LV+ G +YA+K+L KQ+VVK+KQ+EHT +E+R Sbjct 61 SKGKYTLHDFQIMRTLGTGSFGRVHLVRSVHNGRYYAIKVLKKQQVVKMKQVEHTNDERR 120 Query 95 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154 +L+ V PFL+++ +F+D N++MVM+Y+ GGE+FS LR+ RF P A+FYAA+++L Sbjct 121 MLKLVEHPFLIRMWGTFQDARNIFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVILA 180 Query 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSK 214 EYLH+ ++IYRDLKPEN+L+D+ G+I++TDFGFAK V+ TWTLCGTP+Y+APE+I +K Sbjct 181 LEYLHAHNIIYRDLKPENILLDRNGHIKITDFGFAKEVQTVTWTLCGTPDYIAPEVITTK 240 Query 215 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLL 274 YNK+VDWW+LGVLIYEM AGY PF+ P++ YEKI+ GKV +P +F D+ DLL L+ Sbjct 241 PYNKSVDWWSLGVLIYEMLAGYTPFYDTTPMKTYEKILQGKVVYPPYFHPDVVDLLSKLI 300 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKF-KGPGDTSNFDDYEE 333 DLT+R GNL++G DIK H WF+ W + + +E P+ P G GDTS FD Y E Sbjct 301 TADLTRRIGNLQSGSRDIKAHPWFSEVVWERLLAKDIETPYEPPITSGIGDTSLFDQYPE 360 Query 334 EEIRVSIN 341 E++ I Sbjct 361 EQLDYGIQ 368 >Q7JP68.1 RecName: Full=cAMP-dependent protein kinase, catalytic subunit-like [Caenorhabditis elegans] Length=398 Score = 353 bits (907), Expect = 1e-119, Method: Compositional matrix adjust. Identities = 158/312 (51%), Positives = 223/312 (71%), Gaps = 0/312 (0%) Query 23 AKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVK 82 A+E +K +P++ + L +RI T+G G+FGRV L + K TG HYA+K+L+ ++VV Sbjct 69 AEETHMKLSITPTRESFSLSQLERIITIGKGTFGRVELARDKITGAHYALKVLNIRRVVD 128 Query 83 LKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP 142 ++Q +H NEKR+L + PF+VK+ S KD+++LYM+ME+VPGGEMFS+LR FS Sbjct 129 MRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNHLYMIMEFVPGGEMFSYLRASRSFSNS 188 Query 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGT 202 ARFYA++IV EY+HSL ++YRDLKPENL++ ++G+I++ DFGFAK ++ RT+T+CGT Sbjct 189 MARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGT 248 Query 203 PEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF 262 P+YLAPE + G+NK VDWWALG+LIYEM G PPF +IY+ I+ K++FP F Sbjct 249 PDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTSEIYDAIIEHKLKFPRSF 308 Query 263 SSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGP 322 + KDL++ LL+VD T+R G +KNG D+K+HKWF +W +VE P +P P Sbjct 309 NLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEPPIVPTLYHP 368 Query 323 GDTSNFDDYEEE 334 GDT NFDDYEE+ Sbjct 369 GDTGNFDDYEED 380 >P06244.3 RecName: Full=cAMP-dependent protein kinase type 1; Short=PKA 1; AltName: Full=CDC25-suppressing protein kinase; AltName: Full=PK-25 [Saccharomyces cerevisiae S288C] Length=397 Score = 353 bits (905), Expect = 2e-119, Method: Compositional matrix adjust. Identities = 159/329 (48%), Positives = 231/329 (70%), Gaps = 10/329 (3%) Query 13 QESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAM 72 +E K+F+A+A+ + L F ++TLGTGSFGRV L++ + G +YAM Sbjct 65 EEQYKQFIAQAR---------VTSGKYSLQDFQILRTLGTGSFGRVHLIRSRHNGRYYAM 115 Query 73 KILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSH 132 K+L K+ VV+LKQ+EHT +E+ +L V PF++++ +F+D ++M+M+Y+ GGE+FS Sbjct 116 KVLKKEIVVRLKQVEHTNDERLMLSIVTHPFIIRMWGTFQDAQQIFMIMDYIEGGELFSL 175 Query 133 LRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV 192 LR+ RF P A+FYAA++ L EYLHS D+IYRDLKPEN+L+D+ G+I++TDFGFAK V Sbjct 176 LRKSQRFPNPVAKFYAAEVCLALEYLHSKDIIYRDLKPENILLDKNGHIKITDFGFAKYV 235 Query 193 KGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIV 252 T+TLCGTP+Y+APE++ +K YNK++DWW+ G+LIYEM AGY PF+ ++ YEKI+ Sbjct 236 PDVTYTLCGTPDYIAPEVVSTKPYNKSIDWWSFGILIYEMLAGYTPFYDSNTMKTYEKIL 295 Query 253 SGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVE 312 + ++RFP F+ D+KDLL L+ DL++R GNL+NG D+KNH WF W + R +E Sbjct 296 NAELRFPPFFNEDVKDLLSRLITRDLSQRLGNLQNGTEDVKNHPWFKEVVWEKLLSRNIE 355 Query 313 APFIPKF-KGPGDTSNFDDYEEEEIRVSI 340 P+ P +G GDTS FD Y EE+I + Sbjct 356 TPYEPPIQQGQGDTSQFDKYPEEDINYGV 384 >P21901.1 RecName: Full=Spermatozoon-associated protein kinase; Short=SAK; AltName: Full=C-APL-B [Aplysia californica] Length=351 Score = 349 bits (895), Expect = 2e-118, Method: Compositional matrix adjust. Identities = 169/341 (50%), Positives = 236/341 (69%), Gaps = 2/341 (1%) Query 13 QESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKH--KETGNHY 70 Q+ +KE+L + E+F + +T + ++ I+TLG+GSFGRVML +H Y Sbjct 11 QKWLKEYLESSLEQFENLFNKNVISTESIRNYTLIRTLGSGSFGRVMLSQHGGDNPQKCY 70 Query 71 AMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMF 130 A+KIL+K+KVVK+KQ+EHT+NEKRIL ++ PF+V+ +FKD +NLYMVME+V GGE+F Sbjct 71 AIKILNKEKVVKMKQVEHTMNEKRILLSIGSPFVVRCLNAFKDTTNLYMVMEFVNGGELF 130 Query 131 SHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK 190 LR+ GR E FYAAQ+ + +YLH+ L+YRDLKPEN+L+D GY++VTDFGF + Sbjct 131 HLLRKKGRLPEYWCTFYAAQVTMALQYLHNCSLLYRDLKPENILLDHLGYLKVTDFGFDR 190 Query 191 RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEK 250 RV+G TWTLCGTP+YLAPE+IL++ Y LG+LIYE+ AG+ PF P+++YE Sbjct 191 RVQGHTWTLCGTPQYLAPEMILNRSYASQWTTGGLGILIYELNAGFVPFDHKVPLKLYEL 250 Query 251 IVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRK 310 IV ++ FPS F L+DLL N++QVD+T+RFGNL+NG DI NH WF TD+ I + Sbjct 251 IVECRLTFPSFFKPTLRDLLTNIIQVDVTRRFGNLRNGALDIINHPWFKDTDFRKILMKA 310 Query 311 VEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 +AP++P KG FD + EE I +S ++K EF+ F Sbjct 311 EKAPWVPNLKGQWIHQTFDKWTEESISISKHDKYPDEFSNF 351 >A8XJQ6.2 RecName: Full=cAMP-dependent protein kinase, catalytic subunit-like [Caenorhabditis briggsae] Length=385 Score = 346 bits (888), Expect = 7e-117, Method: Compositional matrix adjust. Identities = 158/326 (48%), Positives = 223/326 (68%), Gaps = 14/326 (4%) Query 23 AKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVK 82 A+E +K +P++ + L +RI T+G G+FGRV L + K +G HYA+K+L+ ++VV Sbjct 42 AEETHMKLSITPTRESFSLSQLERIVTIGKGTFGRVELARDKISGAHYALKVLNIRRVVD 101 Query 83 LKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEP 142 ++Q +H NEKR+L + PF+VK+ S KD++NLYM+ME+VPGGEMFS+LR FS Sbjct 102 MRQTQHVHNEKRVLLQLKHPFIVKMYASEKDSNNLYMIMEFVPGGEMFSYLRASRSFSNS 161 Query 143 HARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGT 202 ARFYA++IV EY+HSL ++YRDLKPENL++ ++G+I++ DFGFAK ++ RT+T+CGT Sbjct 162 MARFYASEIVCALEYIHSLGIVYRDLKPENLMLSKEGHIKMADFGFAKELRDRTYTICGT 221 Query 203 PEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHF 262 P+YLAPE + G+NK VDWWALG+LIYEM G PPF +IY+ I+ K++FP F Sbjct 222 PDYLAPESLARTGHNKGVDWWALGILIYEMMVGKPPFRGKTTAEIYDSIIEHKLKFPRSF 281 Query 263 SSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEA--------- 313 + KDL++ LL+VD T+R G +KNG D+K+HKWF +W +VE Sbjct 282 NLAAKDLVKKLLEVDRTQRIGCMKNGTQDVKDHKWFEKVNWDDTLHLRVEVKKLIGIFLI 341 Query 314 -----PFIPKFKGPGDTSNFDDYEEE 334 P +P PGDT NFDDYEE+ Sbjct 342 PIFQPPIVPTLYHPGDTGNFDDYEED 367 >P49673.1 RecName: Full=cAMP-dependent protein kinase catalytic subunit; Short=PKA C [Ascaris suum] Length=337 Score = 342 bits (876), Expect = 7e-116, Method: Compositional matrix adjust. Identities = 158/300 (53%), Positives = 213/300 (71%), Gaps = 0/300 (0%) Query 34 PSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEK 93 P+ N +D FDRI T+GTGSFGRV LV+H+ + ++A+K + ++VV ++Q EH +EK Sbjct 19 PNNNKLNVDDFDRICTIGTGSFGRVYLVQHRASEQYFALKKMAIREVVSMRQTEHVHSEK 78 Query 94 RILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVL 153 R+L ++ PF+VK+ + D NLYM+ EY+ GGE+FS+LR FS ARFYAA+IV Sbjct 79 RLLSRLSHPFIVKMYCASWDKYNLYMLFEYLAGGELFSYLRASRTFSNSMARFYAAEIVC 138 Query 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILS 213 +YLHS ++ YRDLKPENL+++++G++++TDFGFAK V RTWT+CGTPEYLAPE+I + Sbjct 139 ALQYLHSKNIAYRDLKPENLMLNKEGHLKMTDFGFAKEVIDRTWTMCGTPEYLAPEVIGN 198 Query 214 KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 273 KG++ AVDWW+LGVLIYEM G PPF +IYEKI+ GK+RF F KDL++ L Sbjct 199 KGHDTAVDWWSLGVLIYEMMIGIPPFRGKTLDEIYEKIILGKLRFTRSFDLFAKDLVKKL 258 Query 274 LQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEE 333 LQVD T+R GN K+G D+ NHKWF DW + K+ P IP GDT NFD Y+E Sbjct 259 LQVDRTQRLGNQKDGAADVMNHKWFTDIDWDDVQNMKLTPPIIPTLYSNGDTGNFDSYDE 318 >P05986.2 RecName: Full=cAMP-dependent protein kinase type 3; Short=PKA 3 [Saccharomyces cerevisiae S288C] Length=398 Score = 343 bits (881), Expect = 1e-115, Method: Compositional matrix adjust. Identities = 155/301 (51%), Positives = 216/301 (72%), Gaps = 1/301 (0%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 L F ++TLGTGSFGRV L++ G YA+K L K +VKLKQ+EHT +E+R+L V+ Sbjct 85 LSDFQILRTLGTGSFGRVHLIRSNHNGRFYALKTLKKHTIVKLKQVEHTNDERRMLSIVS 144 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PF++++ +F+D+ ++MVM+Y+ GGE+FS LR+ RF P A+FYAA++ L EYLHS Sbjct 145 HPFIIRMWGTFQDSQQVFMVMDYIEGGELFSLLRKSQRFPNPVAKFYAAEVCLALEYLHS 204 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAV 220 D+IYRDLKPEN+L+D+ G+I++TDFGFAK V T+TLCGTP+Y+APE++ +K YNK+V Sbjct 205 KDIIYRDLKPENILLDKNGHIKITDFGFAKYVPDVTYTLCGTPDYIAPEVVSTKPYNKSV 264 Query 221 DWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTK 280 DWW+ GVLIYEM AGY PF+ ++ YE I++ +++FP F D +DLL+ L+ DL++ Sbjct 265 DWWSFGVLIYEMLAGYTPFYNSNTMKTYENILNAELKFPPFFHPDAQDLLKKLITRDLSE 324 Query 281 RFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKF-KGPGDTSNFDDYEEEEIRVS 339 R GNL+NG D+KNH WF W + R +E P+ P +G GDTS FD Y EEE Sbjct 325 RLGNLQNGSEDVKNHPWFNEVIWEKLLARYIETPYEPPIQQGQGDTSQFDRYPEEEFNYG 384 Query 340 I 340 I Sbjct 385 I 385 >P16911.2 RecName: Full=cAMP-dependent protein kinase catalytic subunit 2; AltName: Full=Protein kinase DC1 [Drosophila melanogaster] Length=354 Score = 330 bits (846), Expect = 5e-111, Method: Compositional matrix adjust. Identities = 156/325 (48%), Positives = 216/325 (66%), Gaps = 3/325 (1%) Query 11 SEQESVKEFLAKAKEEFLKKWESPSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNH 69 + +E L EF ++W +Q+ L+++ LG GSFG VMLV+ K N+ Sbjct 11 NSKEDYNVILDNMSREFEERWNHQTQSPYTNLENYITRAVLGNGSFGTVMLVREKSGKNY 70 Query 70 YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM 129 YA K++ K+ +V+LKQ+ H NEK +L A FPFL+ L S K LY+++ V GGE+ Sbjct 71 YAAKMMSKEDLVRLKQVAHVHNEKHVLNAARFPFLIYLVDSTKCFDYLYLILPLVNGGEL 130 Query 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 189 FS+ RR+ +F+E HARFYAAQ+ L EY+H + L+YRDLKPEN+L+DQ+GYI++TDFGF Sbjct 131 FSYHRRVRKFNEKHARFYAAQVALALEYMHKMHLMYRDLKPENILLDQRGYIKITDFGFT 190 Query 190 KRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP--IQI 247 KRV GRT TLCGTPEYLAPEI+ + YNK+VDWWA G+L+YE AG PF I + Sbjct 191 KRVDGRTSTLCGTPEYLAPEIVQLRPYNKSVDWWAFGILVYEFVAGRSPFAIHNRDVILM 250 Query 248 YEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIY 307 Y KI + PS+F+S L+ L+ +L+QVD +KR GN +G +D+K+H WF DW I Sbjct 251 YSKICICDYKMPSYFTSQLRSLVESLMQVDTSKRLGNSNDGSSDVKSHPWFQGVDWFGIL 310 Query 308 QRKVEAPFIPKFKGPGDTSNFDDYE 332 ++V AP+ P G D SNF+++E Sbjct 311 NQEVTAPYQPTISGAEDLSNFENFE 335 >P40376.1 RecName: Full=cAMP-dependent protein kinase catalytic subunit [Schizosaccharomyces pombe 972h-] Length=512 Score = 335 bits (860), Expect = 5e-111, Method: Compositional matrix adjust. Identities = 165/356 (46%), Positives = 234/356 (66%), Gaps = 8/356 (2%) Query 2 GNAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQ----LDHFDRIKTLGTGSFGR 57 G +A G +++ + ++ P+ +T + + F+ ++TLGTGSFGR Sbjct 155 GERRSAMDGLRDRHIRKVRVSQLLDLQRRRIRPADHTTKDRYGIQDFNFLQTLGTGSFGR 214 Query 58 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL 117 V LV+ +YA+K+L+K+K+V +KQIEHT +E+ IL V PF+ L +F+D NL Sbjct 215 VHLVQSNHNRLYYAIKVLEKKKIVDMKQIEHTCDERYILSRVQHPFITILWGTFQDAKNL 274 Query 118 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQ 177 +MVM++ GGE+FS LR+ RF E A+FYAA+++L +YLH ++YRDLKPENLL+D+ Sbjct 275 FMVMDFAEGGELFSLLRKCHRFPEKVAKFYAAEVILALDYLHHNQIVYRDLKPENLLLDR 334 Query 178 QGYIQVTDFGFAKRVK-GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGY 236 G++++ DFGFAKRV TLCGTP+YLAPEII K YNKA DWW+LG+LI+EM AGY Sbjct 335 FGHLKIVDFGFAKRVSTSNCCTLCGTPDYLAPEIISLKPYNKAADWWSLGILIFEMLAGY 394 Query 237 PPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHK 296 PPF+++ P+++YE I+ GKV +PS+FS DLL +LLQ D+T R+GNLK+G DI H Sbjct 395 PPFYSENPMKLYENILEGKVNYPSYFSPASIDLLSHLLQRDITCRYGNLKDGSMDIIMHP 454 Query 297 WFATTDWIAIYQRKVEAPFIPKFK-GPGDTSNFDDYEEEEIRVSINEKCGKEFTEF 351 WF W I RK+E P++P + G GD+S FD Y + +E EFT Sbjct 455 WFRDISWDKILTRKIEVPYVPPIQAGMGDSSQFDAYADVATDYGTSED--PEFTSI 508 >P28178.2 RecName: Full=Protein kinase 2; Short=PK2 [Dictyostelium discoideum] Length=479 Score = 293 bits (749), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 134/299 (45%), Positives = 199/299 (67%), Gaps = 4/299 (1%) Query 33 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 S ++ +A D F+ + +G GSFG+VM VK K +AMK+L K ++ KQ+ HT +E Sbjct 142 SKNKQSATKDDFELLNVIGKGSFGKVMQVKKKGEDKIFAMKVLRKDAIIARKQVNHTKSE 201 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 K ILQ ++ PF+V L ++F+ LYMV+++V GGE+F HL+R GRFSEP + YAA+IV Sbjct 202 KTILQCISHPFIVNLHYAFQTKDKLYMVLDFVNGGELFFHLKREGRFSEPRVKIYAAEIV 261 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR--TWTLCGTPEYLAPEI 210 ++LH D++YRDLKPEN+L+D +G+I +TDFG +K+++ T+T CGTPEYLAPE+ Sbjct 262 SALDHLHKQDIVYRDLKPENILLDSEGHICITDFGLSKKIETTDGTFTFCGTPEYLAPEV 321 Query 211 ILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270 + G+ AVDWW+LG L+YEM G PPF++ +Y+KI++G+++ P++ S + K LL Sbjct 322 LNGHGHGCAVDWWSLGTLLYEMLTGLPPFYSQNVSTMYQKILNGELKIPTYISPEAKSLL 381 Query 271 RNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 LL ++ KR G G ++K H WF DW + +++VE F PK K D S D Sbjct 382 EGLLTREVDKRLGT--KGGGEVKQHPWFKNIDWEKLDRKEVEVHFKPKVKSGTDISQID 438 >Q2PJ68.1 RecName: Full=Serine/threonine-protein kinase sgk-1; AltName: Full=Serum- and glucocorticoid-inducible kinase homolog; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Caenorhabditis elegans] Length=463 Score = 288 bits (738), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 144/299 (48%), Positives = 199/299 (67%), Gaps = 6/299 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS+ TA + FD + T+G GSFGRV V+HKET YAMKIL K+ + K +++H + E Sbjct 124 PSERKTATANDFDYLTTIGKGSFGRVYQVRHKETKKIYAMKILSKEHIRKKNEVKHVMAE 183 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L PFLV L FSF++ LY V++++ GGE+FSHL+R FSE +RFYAA+I Sbjct 184 RNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFSESRSRFYAAEI 243 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAP 208 YLH ++IYRDLKPENLL+D +GY+ +TDFG K ++G T T CGTPEYLAP Sbjct 244 ACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAP 303 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 EIIL K Y+K VDWW LG ++YEM G PPF++ ++Y+KI++ +R + S + Sbjct 304 EIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHNISVPCSE 363 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSN 327 L+ LLQ D +KR G+ +N DI++H +F DW + R+++APFIPK K DTSN Sbjct 364 LITGLLQKDRSKRLGH-RNDFRDIRDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDTSN 421 >P54644.1 RecName: Full=RAC family serine/threonine-protein kinase homolog [Dictyostelium discoideum] Length=444 Score = 285 bits (729), Expect = 3e-92, Method: Compositional matrix adjust. Identities = 144/343 (42%), Positives = 210/343 (61%), Gaps = 12/343 (3%) Query 11 SEQESVK--EFLAKAKEEFLKKWESPSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETG 67 +E+E K E L +E L + P ++ + F+ + +G GSFG+V+ V+ K+TG Sbjct 84 TEEERAKWIEILINERELLLNGGKQPKKSEKVGVADFELLNLVGKGSFGKVIQVRKKDTG 143 Query 68 NHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGG 127 YAMK+L K+ +V+ ++EHTL+E+ ILQ +N PFLV L +SF+ LY +++YV GG Sbjct 144 EVYAMKVLSKKHIVEHNEVEHTLSERNILQKINHPFLVNLNYSFQTEDKLYFILDYVNGG 203 Query 128 EMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFG 187 E+F HL++ +F+E R+Y A+IVL E+LH +IYRDLKPENLL+ +G+I +TDFG Sbjct 204 ELFYHLQKDKKFTEDRVRYYGAEIVLALEHLHLSGVIYRDLKPENLLLTNEGHICMTDFG 263 Query 188 FAKR----VKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQ 243 K +T T CGTPEYLAPE++ GY K VDWW+ G L+YEM G PPF+ Sbjct 264 LCKEGLLTPTDKTGTFCGTPEYLAPEVLQGNGYGKQVDWWSFGSLLYEMLTGLPPFYNQD 323 Query 244 PIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDW 303 ++Y KI+ K+ FP S D + LL LL+ D KR + N IK H +F + DW Sbjct 324 VQEMYRKIMMEKLSFPHFISPDARSLLEQLLERDPEKRLAD----PNLIKRHPFFRSIDW 379 Query 304 IAIYQRKVEAPFIPKFKGPGDTSNFDD-YEEEEIRVSINEKCG 345 ++Q+ + PFIP KG DTS D + +E +++ +C Sbjct 380 EQLFQKNIPPPFIPNVKGSADTSQIDPVFTDEAPSLTMAGECA 422 >O43930.1 PUTATIVE PSEUDOGENE: RecName: Full=Putative serine/threonine-protein kinase PRKY [Homo sapiens] Length=277 Score = 278 bits (712), Expect = 8e-92, Method: Compositional matrix adjust. Identities = 125/235 (53%), Positives = 175/235 (74%), Gaps = 0/235 (0%) Query 33 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 SP +L D + T+GTG+FGRV LVK K + +A+K++ V++ KQ +H NE Sbjct 38 SPEAPAYRLQDCDALVTMGTGTFGRVHLVKEKTAKHFFALKVMSIPDVIRRKQEQHVHNE 97 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 K +L+ V+ PFL++L +++ + LYM+MEYVPGGE+FS+LR G FS FY+A+I+ Sbjct 98 KSVLKEVSHPFLIRLFWTWHEERFLYMLMEYVPGGELFSYLRNRGHFSSTTGLFYSAEII 157 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIIL 212 EYLHS +++YRDLKPEN+L+D+ G+I++TDFGFAK++ RTWTLCGTPEYLAPE+I Sbjct 158 CAIEYLHSKEIVYRDLKPENILLDRDGHIKLTDFGFAKKLVDRTWTLCGTPEYLAPEVIQ 217 Query 213 SKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLK 267 SKG+ +AVDWWALG+LI+EM +G+PPFF D P IY+KI++GK+ FP H +K Sbjct 218 SKGHGRAVDWWALGILIFEMLSGFPPFFDDNPFGIYQKILAGKLYFPRHLDFHVK 272 >A8XNJ6.3 RecName: Full=Serine/threonine-protein kinase sgk-1; AltName: Full=Serum- and glucocorticoid-inducible kinase homolog; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Caenorhabditis briggsae] Length=464 Score = 284 bits (726), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 142/299 (47%), Positives = 197/299 (66%), Gaps = 6/299 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS+ TA + FD + T+G GSFGRV V+HKET YAMK+L K+ + K +++H + E Sbjct 125 PSERKTATANDFDFLTTIGKGSFGRVYQVRHKETKKIYAMKVLSKEHIRKKNEVKHVMAE 184 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L PFLV L FSF++ LY V++++ GGE+FSHL+R F+E +RFYAA+I Sbjct 185 RNVLINNFKHPFLVSLHFSFQNKEKLYFVLDHLNGGELFSHLQREKHFTESRSRFYAAEI 244 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKGR--TWTLCGTPEYLAP 208 YLH ++IYRDLKPENLL+D +GY+ +TDFG K ++G T T CGTPEYLAP Sbjct 245 ACALGYLHEKNIIYRDLKPENLLLDDKGYLVLTDFGLCKEDMQGSKTTSTFCGTPEYLAP 304 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 EIIL K Y+K VDWW LG ++YEM G PPF++ ++Y+KI++ +R S + Sbjct 305 EIILKKPYDKTVDWWCLGSVLYEMIFGLPPFYSKDHNEMYDKIINQPLRLKHTISVPCTE 364 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSN 327 L+ LLQ D +KR G+ KN DI++H +F DW + R+++APFIPK K D SN Sbjct 365 LITGLLQKDRSKRLGH-KNDFRDIQDHPFFLPVDWDKLLNRELKAPFIPKVKNAMDISN 422 >Q6GPN6.1 RecName: Full=Serine/threonine-protein kinase Sgk1-A; AltName: Full=Serum/glucocorticoid-regulated kinase 1-A [Xenopus laevis] Length=434 Score = 281 bits (720), Expect = 7e-91, Method: Compositional matrix adjust. Identities = 145/358 (41%), Positives = 218/358 (61%), Gaps = 19/358 (5%) Query 3 NAAAAKKGSEQESVKEFLAKAKEEFLKKWE------------SPSQNT-AQLDHFDRIKT 49 N++ A K SE +S+ + E L + PS N A+ F +K Sbjct 47 NSSYACKPSEVQSILNISPPQEPELLNENSSPPPSPSQQINLGPSSNPHAKPSDFQFLKI 106 Query 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL-QAVNFPFLVKLE 108 +G GSFG+V+L +H+ YA+K+L K+ ++K K+ +H ++E+ +L + V PFLV L Sbjct 107 IGKGSFGKVLLARHQADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLH 166 Query 109 FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168 FSF+ S LY +++Y+ GGE+F HL+R F EP ARFYAA+I YLHSL+++YRDL Sbjct 167 FSFQTTSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDL 226 Query 169 KPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL 225 KPEN+L+D QG+I +TDFG K G T T CGTPEYLAPE++ + Y++ VDWW L Sbjct 227 KPENILLDSQGHIVLTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCL 286 Query 226 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 285 G ++YEM G PPF++ ++Y+ I++ ++ + ++ ++LL LLQ D TKR G Sbjct 287 GAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIG-A 345 Query 286 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINE 342 KN +IKNH +F+ +W + +K+ PF P GP D +FD ++ EE + SI + Sbjct 346 KNDFMEIKNHIFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQ 403 >Q5BKK4.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Xenopus tropicalis] Length=418 Score = 280 bits (717), Expect = 9e-91, Method: Compositional matrix adjust. Identities = 145/358 (41%), Positives = 217/358 (61%), Gaps = 19/358 (5%) Query 3 NAAAAKKGSEQESVKEFLAKAKEEFLKKWE------------SPSQNT-AQLDHFDRIKT 49 N++ A K SE +S+ + E L + PS N A+ F +K Sbjct 31 NSSYACKHSEVQSILNISPPQEPELLNENSSPPPSPSQQINLGPSSNPHAKPSDFQFLKI 90 Query 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL-QAVNFPFLVKLE 108 +G GSFG+V+L +H YA+K+L K+ ++K K+ +H ++E+ +L + V PFLV L Sbjct 91 IGKGSFGKVLLARHNADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLH 150 Query 109 FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168 FSF+ S LY +++Y+ GGE+F HL+R F EP ARFYAA+I YLHSL+++YRDL Sbjct 151 FSFQTTSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDL 210 Query 169 KPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL 225 KPEN+L+D QG+I +TDFG K G T T CGTPEYLAPE++ + Y++ VDWW L Sbjct 211 KPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAPEVLHKQPYDRTVDWWCL 270 Query 226 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 285 G ++YEM G PPF++ ++Y+ I++ ++ + ++ ++LL LLQ D TKR G Sbjct 271 GAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRIG-A 329 Query 286 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINE 342 KN +IKNH +F+ +W + +K+ PF P GP D +FD ++ EE + SI + Sbjct 330 KNDFMEIKNHMFFSPINWDDLINKKITPPFNPNVSGPSDLQHFDPEFTEEPVPNSIGQ 387 >Q13237.1 RecName: Full=cGMP-dependent protein kinase 2; Short=cGK 2; Short=cGK2; AltName: Full=cGMP-dependent protein kinase II; Short=cGKII [Homo sapiens] Length=762 Score = 289 bits (739), Expect = 3e-90, Method: Compositional matrix adjust. Identities = 143/307 (47%), Positives = 200/307 (65%), Gaps = 10/307 (3%) Query 33 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 SP QN + I TLG G FGRV LVK K +AMK + K+ +V KQ EH +E Sbjct 448 SPFQN------LEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSE 501 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 KRIL+ + PF+VKL +FKDN +YM++E GGE++S LR G F EP ++F A + Sbjct 502 KRILEELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVT 561 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEI 210 F+YLH L +IYRDLKPENL++D +GY+++ DFGFAK++ +TWT CGTPEY+APE+ Sbjct 562 EAFDYLHRLGIIYRDLKPENLILDAEGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEV 621 Query 211 ILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKD 268 IL+KG++ +VD+W+LG+L+YE+ G PPF + Y I+ G K+ FP + +D Sbjct 622 ILNKGHDFSVDFWSLGILVYELLTGNPPFSGVDQMMTYNLILKGIEKMDFPRKITRRPED 681 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 L+R L + + T+R GNLKNG+NDIK H+W +W + R + +P + KGP D S F Sbjct 682 LIRRLCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLQRELKGPIDHSYF 741 Query 329 DDYEEEE 335 D Y E+ Sbjct 742 DKYPPEK 748 >P00516.2 RecName: Full=cGMP-dependent protein kinase 1; Short=cGK 1; Short=cGK1; AltName: Full=cGMP-dependent protein kinase I; Short=cGKI [Bos taurus] Length=671 Score = 286 bits (733), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 138/300 (46%), Positives = 198/300 (66%), Gaps = 5/300 (2%) Query 40 QLDHFDRIKTLGTGSFGRVMLVKHK-ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98 +L F+ I TLG G FGRV LV+ K E +AMKIL K+ +V +Q EH +EK+I+Q Sbjct 356 KLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQG 415 Query 99 VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158 + F+V+L +FKD+ LYM+ME GGE+++ LR G F + RFY A +V F YL Sbjct 416 AHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475 Query 159 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGY 216 HS +IYRDLKPENL++D +GY ++ DFGFAK++ +TWT CGTPEY+APEIIL+KG+ Sbjct 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLL 274 + + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP + + +L++ L Sbjct 536 DISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLC 595 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 334 + + ++R GNLKNGV DI+ HKWF +W + + + P IP P DTSNFD + E+ Sbjct 596 RDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPED 655 >Q13976.3 RecName: Full=cGMP-dependent protein kinase 1; Short=cGK 1; Short=cGK1; AltName: Full=cGMP-dependent protein kinase I; Short=cGKI [Homo sapiens] Length=671 Score = 286 bits (732), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 138/300 (46%), Positives = 198/300 (66%), Gaps = 5/300 (2%) Query 40 QLDHFDRIKTLGTGSFGRVMLVKHK-ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98 +L F+ I TLG G FGRV LV+ K E +AMKIL K+ +V +Q EH +EK+I+Q Sbjct 356 KLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQG 415 Query 99 VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158 + F+V+L +FKD+ LYM+ME GGE+++ LR G F + RFY A +V F YL Sbjct 416 AHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475 Query 159 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGY 216 HS +IYRDLKPENL++D +GY ++ DFGFAK++ +TWT CGTPEY+APEIIL+KG+ Sbjct 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLL 274 + + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP + + +L++ L Sbjct 536 DISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLC 595 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 334 + + ++R GNLKNGV DI+ HKWF +W + + + P IP P DTSNFD + E+ Sbjct 596 RDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPED 655 >P0C605.1 RecName: Full=cGMP-dependent protein kinase 1; Short=cGK 1; Short=cGK1; AltName: Full=cGMP-dependent protein kinase I; Short=cGKI [Mus musculus] Length=671 Score = 286 bits (732), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 138/300 (46%), Positives = 198/300 (66%), Gaps = 5/300 (2%) Query 40 QLDHFDRIKTLGTGSFGRVMLVKHK-ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98 +L F+ I TLG G FGRV LV+ K E +AMKIL K+ +V +Q EH +EK+I+Q Sbjct 356 KLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQG 415 Query 99 VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158 + F+V+L +FKD+ LYM+ME GGE+++ LR G F + RFY A +V F YL Sbjct 416 AHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475 Query 159 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGY 216 HS +IYRDLKPENL++D +GY ++ DFGFAK++ +TWT CGTPEY+APEIIL+KG+ Sbjct 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLL 274 + + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP + + +L++ L Sbjct 536 DISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLC 595 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 334 + + ++R GNLKNGV DI+ HKWF +W + + + P IP P DTSNFD + E+ Sbjct 596 RDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDSFPED 655 >O77676.3 RecName: Full=cGMP-dependent protein kinase 1; Short=cGK 1; Short=cGK1 [Oryctolagus cuniculus] Length=671 Score = 286 bits (732), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 138/300 (46%), Positives = 198/300 (66%), Gaps = 5/300 (2%) Query 40 QLDHFDRIKTLGTGSFGRVMLVKHK-ETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQA 98 +L F+ I TLG G FGRV LV+ K E +AMKIL K+ +V +Q EH +EK+I+Q Sbjct 356 KLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQG 415 Query 99 VNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYL 158 + F+V+L +FKD+ LYM+ME GGE+++ LR G F + RFY A +V F YL Sbjct 416 AHSDFIVRLYRTFKDSKYLYMLMEACLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYL 475 Query 159 HSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKGY 216 HS +IYRDLKPENL++D +GY ++ DFGFAK++ +TWT CGTPEY+APEIIL+KG+ Sbjct 476 HSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEIILNKGH 535 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLL 274 + + D+W+LG+L+YE+ G PPF P++ Y I+ G + FP + + +L++ L Sbjct 536 DISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLC 595 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEE 334 + + ++R GNLKNGV DI+ HKWF +W + + + P IP P DTSNFD + E+ Sbjct 596 RDNPSERLGNLKNGVKDIQKHKWFEGFNWEGLRKGTLTPPIIPSVASPTDTSNFDGFPED 655 >Q17941.2 RecName: Full=Serine/threonine-protein kinase akt-1; AltName: Full=Protein kinase B akt-1; Short=PKB akt-1 [Caenorhabditis elegans] Length=541 Score = 282 bits (722), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 130/302 (43%), Positives = 193/302 (64%), Gaps = 3/302 (1%) Query 32 ESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91 E+ ++ ++ FD +K LG G+FG+V+L K K T YA+KIL K ++ +++ HTL Sbjct 181 EAAKRDKITMEDFDFLKVLGKGTFGKVILCKEKRTQKLYAIKILKKDVIIAREEVAHTLT 240 Query 92 EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 E R+LQ PFL +L++SF++ L VM++ GGE+F+H+R+ G FSEP ARFY A+I Sbjct 241 ENRVLQRCKHPFLTELKYSFQEQHYLCFVMQFANGGELFTHVRKCGTFSEPRARFYGAEI 300 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAP 208 VL YLH D++YRD+K ENLL+D+ G+I++ DFG K +T T CGTPEYLAP Sbjct 301 VLALGYLHRCDIVYRDMKLENLLLDKDGHIKIADFGLCKEEISFGDKTSTFCGTPEYLAP 360 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ Y + VDWW +GV++YEM G PF++ +++E I++G +RFPS S + + Sbjct 361 EVLDDHDYGRCVDWWGVGVVMYEMMCGRLPFYSKDHNKLFELIMAGDLRFPSKLSQEART 420 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LL D T+R G +I +F T DW A Y++++E P+ P + DTS F Sbjct 421 LLTGLLVKDPTQRLGGGPEDALEICRADFFRTVDWEATYRKEIEPPYKPNVQSETDTSYF 480 Query 329 DD 330 D+ Sbjct 481 DN 482 >Q6GLY8.1 RecName: Full=Serine/threonine-protein kinase Sgk1-B; AltName: Full=Serum/glucocorticoid-regulated kinase 1-B [Xenopus laevis] Length=434 Score = 279 bits (713), Expect = 6e-90, Method: Compositional matrix adjust. Identities = 143/358 (40%), Positives = 216/358 (60%), Gaps = 19/358 (5%) Query 3 NAAAAKKGSEQESVKEFLAKAKEEFLKKWESP-------------SQNTAQLDHFDRIKT 49 N++ + K SE +S+ + E L + SP S A+ F +K Sbjct 47 NSSYSCKPSEVQSILNISPPQESELLNENSSPPPSHSQQINLGPSSNPHAKPSDFQFLKI 106 Query 50 LGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL-QAVNFPFLVKLE 108 +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E+ +L + V PFLV L Sbjct 107 IGKGSFGKVLLARHKADEKFYAVKVLQKKAILKKKEEKHIMSERNVLLKNVKHPFLVGLH 166 Query 109 FSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDL 168 FS + S LY +++Y+ GGE+F HL+R F EP ARFYAA+I YLHSL+++YRDL Sbjct 167 FSIQTTSRLYFILDYINGGELFYHLQRERCFLEPRARFYAAEIASALGYLHSLNIVYRDL 226 Query 169 KPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL 225 KPEN+L+D QG+I +TDFG K G T T CGTPEYLAPE++ + Y++ VDWW L Sbjct 227 KPENILLDSQGHIVLTDFGLCKENIEPNGITSTFCGTPEYLAPEVLHKQPYDRTVDWWCL 286 Query 226 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 285 G ++YEM G PPF++ ++Y+ I++ ++ + ++ ++LL LLQ D TKR G Sbjct 287 GAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARNLLEGLLQKDRTKRTG-A 345 Query 286 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEIRVSINE 342 K +IKNH +F+ DW + +K+ PF P GP D +FD ++ +E + SI + Sbjct 346 KTDFMEIKNHIFFSPIDWDDLINKKITPPFNPNVSGPSDLQHFDPEFTDEPVPNSIGQ 403 >Q64595.1 RecName: Full=cGMP-dependent protein kinase 2; Short=cGK 2; Short=cGK2; AltName: Full=cGMP-dependent protein kinase II; Short=cGKII [Rattus norvegicus] Length=762 Score = 287 bits (735), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 139/303 (46%), Positives = 198/303 (65%), Gaps = 4/303 (1%) Query 37 NTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96 +T+ + + I TLG G FGRV LVK K +AMK + K+ +V KQ EH +EKRIL Sbjct 446 STSPFQNLEIIATLGVGGFGRVELVKVKNENIAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505 Query 97 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156 + + PF+VKL +FKDN +YM++E GGE++S LR G F EP ++F A + F+ Sbjct 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565 Query 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSK 214 YLH L +IYRDLKPENL++D GY+++ DFGFAK++ +TWT CGTPEY+APE+IL+K Sbjct 566 YLHRLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625 Query 215 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRN 272 G++ +VD+W+LG+L+YE+ G PPF + Y I+ G K+ FP + +DL+R Sbjct 626 GHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685 Query 273 LLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYE 332 L + + T+R GNLKNG+NDIK H+W +W + R + +P + GP D S FD Y Sbjct 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYP 745 Query 333 EEE 335 E+ Sbjct 746 PEK 748 >Q61410.1 RecName: Full=cGMP-dependent protein kinase 2; Short=cGK 2; Short=cGK2; AltName: Full=cGMP-dependent protein kinase II; Short=cGKII [Mus musculus] Length=762 Score = 287 bits (734), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 139/303 (46%), Positives = 198/303 (65%), Gaps = 4/303 (1%) Query 37 NTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96 +T+ + + I TLG G FGRV LVK K +AMK + K+ +V KQ EH +EKRIL Sbjct 446 STSPFQNLEIIATLGVGGFGRVELVKVKNENVAFAMKCIRKKHIVDTKQQEHVYSEKRIL 505 Query 97 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156 + + PF+VKL +FKDN +YM++E GGE++S LR G F EP ++F A + F+ Sbjct 506 EELCSPFIVKLYRTFKDNKYVYMLLEACLGGELWSILRDRGSFDEPTSKFCVACVTEAFD 565 Query 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSK 214 YLH L +IYRDLKPENL++D GY+++ DFGFAK++ +TWT CGTPEY+APE+IL+K Sbjct 566 YLHLLGIIYRDLKPENLILDADGYLKLVDFGFAKKIGSGQKTWTFCGTPEYVAPEVILNK 625 Query 215 GYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRN 272 G++ +VD+W+LG+L+YE+ G PPF + Y I+ G K+ FP + +DL+R Sbjct 626 GHDFSVDFWSLGILVYELLTGNPPFSGIDQMMTYNLILKGIEKMDFPRKITRRPEDLIRR 685 Query 273 LLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYE 332 L + + T+R GNLKNG+NDIK H+W +W + R + +P + GP D S FD Y Sbjct 686 LCRQNPTERLGNLKNGINDIKKHRWLNGFNWEGLKARSLPSPLRRELSGPIDHSYFDKYP 745 Query 333 EEE 335 E+ Sbjct 746 PEK 748 >Q9P7J8.1 RecName: Full=Serine/threonine-protein kinase gad8 [Schizosaccharomyces pombe 972h-] Length=569 Score = 282 bits (721), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 138/307 (45%), Positives = 193/307 (63%), Gaps = 6/307 (2%) Query 34 PSQNTA-QLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 P+Q+T +D F+ +K +G GSFG+VM V+ ++T YA+K + K +V +++HTL E Sbjct 219 PNQSTPLTIDAFELLKVVGKGSFGKVMQVRKRDTSRIYALKTMKKAHIVSRSEVDHTLAE 278 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 + +L VN PF+V L+FSF+ LY+V+ +V GGE+F HL+R G F A+FY A+++ Sbjct 279 RTVLAQVNNPFIVPLKFSFQSPGKLYLVLAFVNGGELFHHLQREGCFDTYRAKFYIAELL 338 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPE 209 + E LH ++IYRDLKPEN+L+D G+I + DFG K RT T CGTPEYLAPE Sbjct 339 VALECLHEFNVIYRDLKPENILLDYTGHIALCDFGLCKLNMAKTDRTNTFCGTPEYLAPE 398 Query 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 ++L GY K VDWW LGVL+YEM G PPF+ + ++Y KI+ +RFP + KDL Sbjct 399 LLLGHGYTKVVDWWTLGVLLYEMITGLPPFYDENINEMYRKILQDPLRFPDNIDEKAKDL 458 Query 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 L LL KR G+ G +IKNH +F DW + +K++ PF P + DTSNFD Sbjct 459 LSGLLTRAPEKRLGS--GGAQEIKNHPFFDDIDWKKLCAKKIQPPFKPSVESAIDTSNFD 516 Query 330 DYEEEEI 336 EI Sbjct 517 SEFTSEI 523 >Q7ZTW4.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Danio rerio] Length=433 Score = 277 bits (709), Expect = 3e-89, Method: Compositional matrix adjust. Identities = 136/313 (43%), Positives = 202/313 (65%), Gaps = 7/313 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N TA+ FD +K +G GSFG+V+L +H+ YA+K+L K+ ++K K+ +H ++E Sbjct 89 PSSNPTAKPSDFDFLKVIGKGSFGKVLLARHRSDEKFYAVKVLQKKAILKKKEEKHIMSE 148 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 149 RNVLLKNVKHPFLVGLHYSFQTTDKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 208 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 209 ASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAP 268 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + S+ + Sbjct 269 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARH 328 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G + +IKNH +F+ +W + +K+ PF P GP D +F Sbjct 329 LLEGLLQKDRTKRLG-FTDDFTEIKNHMFFSPINWDDLNAKKLTPPFNPNVTGPNDLRHF 387 Query 329 D-DYEEEEIRVSI 340 D ++ +E + SI Sbjct 388 DPEFTDEPVPNSI 400 >Q8R4U9.2 RecName: Full=Serine/threonine-protein kinase Sgk2; AltName: Full=Serum/glucocorticoid-regulated kinase 2 [Rattus norvegicus] Length=367 Score = 274 bits (701), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 138/313 (44%), Positives = 199/313 (64%), Gaps = 7/313 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ FD +K +G G++G+V+L K K G YA+K+L K+ ++K K+ H + E Sbjct 24 PSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQSHIMAE 83 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V++YV GGE+F HL+R RF EP ARFY A++ Sbjct 84 RNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQREHRFLEPRARFYTAEV 143 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL++IYRDLKPEN+L+D QG++ +TDFG K + T T CGTPEYLAP Sbjct 144 ASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAP 203 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++AVDWW LG ++YEM G PPFF Q+YE I+ ++ P + D Sbjct 204 EVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACD 263 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL+ LL D +R G+ K DIKNH +F+ +W +Y +++ PF P +GP D +F Sbjct 264 LLQGLLHKDQRQRLGS-KEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHF 322 Query 329 D-DYEEEEIRVSI 340 D ++ +E + SI Sbjct 323 DPEFTQEAVSKSI 335 >Q9QZS5.1 RecName: Full=Serine/threonine-protein kinase Sgk2; AltName: Full=Serum/glucocorticoid-regulated kinase 2 [Mus musculus] Length=367 Score = 274 bits (700), Expect = 7e-89, Method: Compositional matrix adjust. Identities = 138/313 (44%), Positives = 199/313 (64%), Gaps = 7/313 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ FD +K +G G++G+V+L K K G YA+K+L K+ ++K K+ H + E Sbjct 24 PSANPNARPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKNKEQNHIMAE 83 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V++YV GGE+F HL+R RF EP ARFY A++ Sbjct 84 RNVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYTAEV 143 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL++IYRDLKPEN+L+D QG++ +TDFG K + T T CGTPEYLAP Sbjct 144 ASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKECVEPEETTSTFCGTPEYLAP 203 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++AVDWW LG ++YEM G PPFF Q+YE I+ ++ P + D Sbjct 204 EVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFFNTDVAQMYENILHQPLQIPGGRTVAACD 263 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL+ LL D +R G+ K DIKNH +F+ +W +Y +++ PF P +GP D +F Sbjct 264 LLQGLLHKDQRQRLGS-KEDFLDIKNHMFFSPINWDDLYHKRLTPPFNPNVEGPADLKHF 322 Query 329 D-DYEEEEIRVSI 340 D ++ +E + SI Sbjct 323 DPEFTQEAVSKSI 335 >Q6U1I9.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Gallus gallus] Length=432 Score = 275 bits (704), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 136/315 (43%), Positives = 201/315 (64%), Gaps = 7/315 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 88 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEQFYAVKVLQKKAILKKKEEKHIMSE 147 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 148 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 207 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 208 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAP 267 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 268 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 327 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K +IKNH +F+ +W + +K+ PF P GP D +F Sbjct 328 LLEGLLQKDRTKRLG-AKEDFTEIKNHIFFSPINWDDLINKKITPPFNPNVSGPSDLRHF 386 Query 329 D-DYEEEEIRVSINE 342 D ++ +E + SI + Sbjct 387 DPEFTDEPVPNSIGQ 401 >Q9XT18.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Oryctolagus cuniculus] Length=431 Score = 275 bits (703), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 136/313 (43%), Positives = 201/313 (64%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K+ +I+NH +F+ +W + +K+ PF P GP D +F Sbjct 327 LLEGLLQKDRTKRLG-AKDDFMEIRNHVFFSLINWDDLINKKITPPFNPNVSGPSDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 386 DPEFTEEPVPSSI 398 >P12688.2 RecName: Full=Serine/threonine-protein kinase YPK1; AltName: Full=Sphingosine-like immunosuppressant resistant protein 2; AltName: Full=Yeast protein kinase 1 [Saccharomyces cerevisiae S288C] Length=680 Score = 282 bits (721), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 136/301 (45%), Positives = 193/301 (64%), Gaps = 6/301 (2%) Query 34 PSQNTA-QLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS+N +D FD +K +G GSFG+VM V+ K+T YA+K + K +V ++ HTL E Sbjct 336 PSRNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKVYALKAIRKSYIVSKSEVTHTLAE 395 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 + +L V+ PF+V L+FSF+ LY V+ ++ GGE+F HL++ GRF ARFY A+++ Sbjct 396 RTVLARVDCPFIVPLKFSFQSPEKLYFVLAFINGGELFYHLQKEGRFDLSRARFYTAELL 455 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPE 209 + LH LD++YRDLKPEN+L+D QG+I + DFG K + +T T CGTPEYLAPE Sbjct 456 CALDNLHKLDVVYRDLKPENILLDYQGHIALCDFGLCKLNMKDDDKTDTFCGTPEYLAPE 515 Query 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 ++L GY KAVDWW LGVL+YEM G PP++ + ++Y+KI+ + FP F D KDL Sbjct 516 LLLGLGYTKAVDWWTLGVLLYEMLTGLPPYYDEDVPKMYKKILQEPLVFPDGFDRDAKDL 575 Query 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 L LL D T+R G NG ++I+NH +F+ W + + P+ P DTSNFD Sbjct 576 LIGLLSRDPTRRLG--YNGADEIRNHPFFSQLSWKRLLMKGYIPPYKPAVSNSMDTSNFD 633 Query 330 D 330 + Sbjct 634 E 634 >Q9HBY8.1 RecName: Full=Serine/threonine-protein kinase Sgk2; AltName: Full=Serum/glucocorticoid-regulated kinase 2 [Homo sapiens] Length=427 Score = 274 bits (701), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 138/313 (44%), Positives = 201/313 (64%), Gaps = 7/313 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N AQ FD +K +G G++G+V+L K K G YA+K+L K+ ++K K+ H + E Sbjct 84 PSANPNAQPTDFDFLKVIGKGNYGKVLLAKRKSDGAFYAVKVLQKKSILKKKEQSHIMAE 143 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V++YV GGE+F HL+R RF EP ARFYAA++ Sbjct 144 RSVLLKNVRHPFLVGLRYSFQTPEKLYFVLDYVNGGELFFHLQRERRFLEPRARFYAAEV 203 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAP 208 YLHSL++IYRDLKPEN+L+D QG++ +TDFG K + T T CGTPEYLAP Sbjct 204 ASAIGYLHSLNIIYRDLKPENILLDCQGHVVLTDFGLCKEGVEPEDTTSTFCGTPEYLAP 263 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++AVDWW LG ++YEM G PPF++ Q+YE I+ ++ P + D Sbjct 264 EVLRKEPYDRAVDWWCLGAVLYEMLHGLPPFYSQDVSQMYENILHQPLQIPGGRTVAACD 323 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL++LL D +R G+ K +IKNH +F+ +W +Y +++ PF P GP D +F Sbjct 324 LLQSLLHKDQRQRLGS-KADFLEIKNHVFFSPINWDDLYHKRLTPPFNPNVTGPADLKHF 382 Query 329 D-DYEEEEIRVSI 340 D ++ +E + SI Sbjct 383 DPEFTQEAVSKSI 395 >A7MB74.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Bos taurus] Length=431 Score = 274 bits (700), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 136/313 (43%), Positives = 201/313 (64%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 +L LLQ D TKR G K+ +IKNH +F+ +W + +K+ PF P GP D +F Sbjct 327 VLEGLLQKDRTKRLG-AKDDFMEIKNHVFFSLINWEDLINKKITPPFNPNVSGPSDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 386 DPEFTEEPVPNSI 398 >Q5Q0U5.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Fundulus heteroclitus] Length=431 Score = 274 bits (700), Expect = 6e-88, Method: Compositional matrix adjust. Identities = 134/313 (43%), Positives = 202/313 (65%), Gaps = 7/313 (2%) Query 34 PSQN-TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N +A+ F +K +G GSFG+V+L +H+ YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPSAKPSDFHFLKVIGKGSFGKVLLARHRTDDQFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V++Y+ GGE+F HL+R F EP ARFY+A+I Sbjct 147 RNVLLKNVKHPFLVGLHYSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYSAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIILTDFGLCKENIEPNGTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + S+ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNISNAARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K+ +IKNH +F+ +W + +K+ PF P GP D +F Sbjct 327 LLEGLLQKDRTKRLG-CKDDFTEIKNHVFFSPINWDDLNAKKMTPPFNPNVTGPNDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ +E + SI Sbjct 386 DPEFTDEPVPSSI 398 >Q9WVC6.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Mus musculus] Length=431 Score = 273 bits (698), Expect = 1e-87, Method: Compositional matrix adjust. Identities = 136/313 (43%), Positives = 201/313 (64%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K+ +IK+H +F+ +W + +K+ PF P GP D +F Sbjct 327 LLEGLLQKDRTKRLG-AKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 386 DPEFTEEPVPSSI 398 >Q7ZX15.1 RecName: Full=RAC-beta serine/threonine-protein kinase A; AltName: Full=Protein kinase Akt-2-A; AltName: Full=Protein kinase B, beta-A; Short=PKB beta-A; AltName: Full=RAC-PK-beta-A [Xenopus laevis] Length=486 Score = 273 bits (697), Expect = 7e-87, Method: Compositional matrix adjust. Identities = 129/293 (44%), Positives = 188/293 (64%), Gaps = 3/293 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K TG +YAMKIL K+ ++ ++ HTL E R+LQ Sbjct 154 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTLTESRVLQNTK 213 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L+++F+ + L VMEY GGE+F HL R F+E ARFY A+IV EYLHS Sbjct 214 HPFLTALKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS 273 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYN 217 +++YRD+K ENL++D+ G++++TDFG K G T T CGTPEYLAPE++ Y Sbjct 274 RNVVYRDIKLENLMLDKDGHVKITDFGLCKEGITDGATMRTFCGTPEYLAPEVLEDNDYG 333 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ ++RFP S + K LL LL+ D Sbjct 334 RAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSLLAGLLKKD 393 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 +R G N ++ +H++F + +W + +RK+ PF P+ DT FDD Sbjct 394 PKQRLGGGPNDAQEVMSHRFFVSINWQDVTERKLTPPFKPQVTSEIDTRYFDD 446 >O00141.2 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Homo sapiens] Length=431 Score = 270 bits (691), Expect = 1e-86, Method: Compositional matrix adjust. Identities = 135/313 (43%), Positives = 200/313 (64%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K+ +IK+H +F+ +W + +K+ PF P GP D +F Sbjct 327 LLEGLLQKDRTKRLG-AKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 386 DPEFTEEPVPNSI 398 >Q06226.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Rattus norvegicus] Length=430 Score = 270 bits (690), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 136/313 (43%), Positives = 201/313 (64%), Gaps = 8/313 (3%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEAFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K G T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNGTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQL-KNITNSARH 325 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D TKR G K+ +IK+H +F+ +W + +K+ PF P GP D +F Sbjct 326 LLEGLLQKDRTKRLG-AKDDFMEIKSHIFFSLINWDDLINKKITPPFNPNVSGPSDLRHF 384 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 385 DPEFTEEPVPSSI 397 >P34102.2 RecName: Full=Protein kinase 3; Short=PK3 [Dictyostelium discoideum] Length=910 Score = 281 bits (720), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 130/292 (45%), Positives = 190/292 (65%), Gaps = 13/292 (4%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 +D F+ +K LG GSFGRV LV+ K+TG YAMK+L+K+ ++K KQI HT EK +L ++ Sbjct 495 IDDFELLKVLGVGSFGRVYLVRRKDTGKFYAMKVLNKKDMLKKKQIAHTNTEKMVLSTMD 554 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PF+V+L F+F++ L+M M+YVPGGE+F HL++ G+F E A+FY A+++ + YLHS Sbjct 555 HPFIVRLHFAFQNEDFLFMCMDYVPGGELFHHLQKAGKFPEELAKFYIAEVICSLHYLHS 614 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR------------VKGRTWTLCGTPEYLAP 208 ++IYRD+KPEN+L+D++G+I++TDFG +K G T CGTPEYLAP Sbjct 615 NNIIYRDIKPENILLDEEGHIKLTDFGLSKSGITSVVGSKNGGEGGFATTFCGTPEYLAP 674 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 EII G+ KA DWW++G+L++EM G PF A +Y+ ++ G +R P SSD +D Sbjct 675 EIITGAGHGKAADWWSVGILLFEMLTGRSPFLASNRNDMYKSMIQGNLRMPMFLSSDAQD 734 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFK 320 LL LL D KR G+ + G +I +H +F W + + + PF P K Sbjct 735 LLEKLLVPDPNKRLGSTQ-GFEEISSHPFFELIPWRMLESKMITPPFKPTIK 785 >P31751.2 RecName: Full=RAC-beta serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-2; AltName: Full=Protein kinase B beta; Short=PKB beta; AltName: Full=RAC-PK-beta [Homo sapiens] Length=481 Score = 271 bits (693), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 130/301 (43%), Positives = 190/301 (63%), Gaps = 3/301 (1%) Query 33 SPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 S ++ ++ FD +K LG G+FG+V+LV+ K TG +YAMKIL K+ ++ ++ HT+ E Sbjct 141 SKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTE 200 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 R+LQ PFL L+++F+ + L VMEY GGE+F HL R F+E ARFY A+IV Sbjct 201 SRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEERARFYGAEIV 260 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPE 209 EYLHS D++YRD+K ENL++D+ G+I++TDFG K G T T CGTPEYLAPE Sbjct 261 SALEYLHSRDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPE 320 Query 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 ++ Y +AVDWW LGV++YEM G PF+ +++E I+ ++RFP S + K L Sbjct 321 VLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLSPEAKSL 380 Query 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 L LL+ D +R G + ++ H++F + +W + Q+K+ PF P+ DT FD Sbjct 381 LAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFD 440 Query 330 D 330 D Sbjct 441 D 441 >Q4R633.1 RecName: Full=Serine/threonine-protein kinase Sgk1; AltName: Full=Serum/glucocorticoid-regulated kinase 1 [Macaca fascicularis] Length=431 Score = 268 bits (686), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 134/313 (43%), Positives = 199/313 (64%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ F +K +G GSFG+V+L +HK YA+K+L K+ ++K K+ +H ++E Sbjct 87 PSSNPHAKPSDFHFLKVIGKGSFGKVLLARHKAEEVFYAVKVLQKKAILKKKEEKHIMSE 146 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L FSF+ LY V++Y+ GGE+F HL+R F EP ARFYAA+I Sbjct 147 RNVLLKNVKHPFLVGLHFSFQTADKLYFVLDYINGGELFYHLQRERCFLEPRARFYAAEI 206 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAP 208 YLHSL+++YRDLKPEN+L+D QG+I +TDFG K T T CGTPEYLAP Sbjct 207 ASALGYLHSLNIVYRDLKPENILLDSQGHIVLTDFGLCKENIEHNSTTSTFCGTPEYLAP 266 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E++ + Y++ VDWW LG ++YEM G PPF++ ++Y+ I++ ++ + ++ + Sbjct 267 EVLHKQPYDRTVDWWCLGAVLYEMLYGLPPFYSRNTAEMYDNILNKPLQLKPNITNSARH 326 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LLQ D KR G K+ +IK+H +F+ +W + +K+ PF P GP D +F Sbjct 327 LLEGLLQKDRMKRLG-AKDDFMEIKSHVFFSLINWDDLINKKITPPFNPNVSGPNDLRHF 385 Query 329 D-DYEEEEIRVSI 340 D ++ EE + SI Sbjct 386 DPEFTEEPVPNSI 398 >P18961.1 RecName: Full=Serine/threonine-protein kinase YPK2/YKR2 [Saccharomyces cerevisiae S288C] Length=677 Score = 275 bits (704), Expect = 8e-86, Method: Compositional matrix adjust. Identities = 135/300 (45%), Positives = 191/300 (64%), Gaps = 6/300 (2%) Query 34 PSQNTA-QLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS+N +D FD +K +G GSFG+VM V+ K+T YA+K L K +V ++ HTL E Sbjct 333 PSKNKPLSIDDFDLLKVIGKGSFGKVMQVRKKDTQKIYALKALRKAYIVSKCEVTHTLAE 392 Query 93 KRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIV 152 + +L V+ PF+V L+FSF+ LY+V+ ++ GGE+F HL+ GRFS +RFY A+++ Sbjct 393 RTVLARVDCPFIVPLKFSFQSPEKLYLVLAFINGGELFYHLQHEGRFSLARSRFYIAELL 452 Query 153 LTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPE 209 + LH LD+IYRDLKPEN+L+D QG+I + DFG K + +T T CGTPEYLAPE Sbjct 453 CALDSLHKLDVIYRDLKPENILLDYQGHIALCDFGLCKLNMKDNDKTDTFCGTPEYLAPE 512 Query 210 IILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDL 269 I+L +GY K VDWW LG+L+YEM G PP++ + +Y+KI+ + FP F KDL Sbjct 513 ILLGQGYTKTVDWWTLGILLYEMMTGLPPYYDENVPVMYKKILQQPLLFPDGFDPAAKDL 572 Query 270 LRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 L LL D ++R G NG ++I+NH +F W + + P+ P K DT+NFD Sbjct 573 LIGLLSRDPSRRLG--VNGTDEIRNHPFFKDISWKKLLLKGYIPPYKPIVKSEIDTANFD 630 >P47197.1 RecName: Full=RAC-beta serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-2; AltName: Full=Protein kinase B beta; Short=PKB beta; AltName: Full=RAC-PK-beta [Rattus norvegicus] Length=481 Score = 269 bits (688), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 134/331 (40%), Positives = 201/331 (61%), Gaps = 10/331 (3%) Query 3 NAAAAKKGSEQESVKEFLAKAKEEFLKKWESPSQNTAQLDHFDRIKTLGTGSFGRVMLVK 62 +A K GS +S + E ++ S ++ ++ FD +K LG G+FG+V+LV+ Sbjct 118 DAMDYKCGSPSDS-------STSEMMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVR 170 Query 63 HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVME 122 K TG +YAMKIL K+ ++ ++ HT+ E R+LQ PFL L+++F+ + L VME Sbjct 171 EKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVME 230 Query 123 YVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQ 182 Y GG++F HL R F+E ARFY A+IV EYLHS D++YRD+K ENL++D+ G+I+ Sbjct 231 YANGGDLFFHLSRERVFTEDRARFYGAEIVSALEYLHSTDVVYRDIKLENLMLDKDGHIK 290 Query 183 VTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF 239 +TDFG +K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM G PF Sbjct 291 ITDFGLSKEGISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPF 350 Query 240 FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFA 299 + +++E I+ ++RFP + K LL LL+ D +R G + ++ H++F Sbjct 351 YNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFL 410 Query 300 TTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 + +W + Q+K+ PF P+ DT FDD Sbjct 411 SINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441 >P47196.1 RecName: Full=RAC-alpha serine/threonine-protein kinase; AltName: Full=Protein kinase B; Short=PKB; AltName: Full=Protein kinase B alpha; Short=PKB alpha; AltName: Full=RAC-PK-alpha [Rattus norvegicus] Length=480 Score = 269 bits (687), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 141/337 (42%), Positives = 202/337 (60%), Gaps = 20/337 (6%) Query 14 ESVKEFLAKAKEEFLK-KWESPSQNTA---------------QLDHFDRIKTLGTGSFGR 57 ++V + L + +EE + + SPS N+ ++ F+ +K LG G+FG+ Sbjct 104 QTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVALAKPKHRVTMNEFEYLKLLGKGTFGK 163 Query 58 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL 117 V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ PFL L++SF+ + L Sbjct 164 VILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRL 223 Query 118 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID 176 VMEY GGE+F HL R FSE ARFY A+IV +YLHS +++YRDLK ENL++D Sbjct 224 CFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD 283 Query 177 QQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 233 + G+I++TDFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM Sbjct 284 KDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMM 343 Query 234 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIK 293 G PF+ +++E I+ ++RFP + K LL LL+ D T+R G +I Sbjct 344 CGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 403 Query 294 NHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 H++FA W +Y++K+ PF P+ DT FD+ Sbjct 404 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDE 440 >Q6IP76.1 RecName: Full=RAC-beta serine/threonine-protein kinase B; AltName: Full=Protein kinase Akt-2-B; AltName: Full=Protein kinase B, beta-B; Short=PKB beta-B; AltName: Full=RAC-PK-beta-B [Xenopus laevis] Length=485 Score = 269 bits (688), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 129/293 (44%), Positives = 187/293 (64%), Gaps = 3/293 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K TG +YAMKIL K+ ++ ++ HTL E R+LQ Sbjct 153 MNDFDYLKLLGKGTFGKVILVREKATGLYYAMKILRKEVIIAKDEVAHTLTESRVLQNTK 212 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L+++F+ + L VMEY GGE+F HL R F+E ARFY A+IV EYLHS Sbjct 213 HPFLTGLKYAFQTSDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS 272 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYN 217 +++YRD+K ENL++D+ G++++TDFG K G T T CGTPEYLAPE++ Y Sbjct 273 RNVVYRDIKLENLMLDKDGHVKITDFGLCKEGITDGATMRTFCGTPEYLAPEVLEDNDYG 332 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ + RFP S + K LL LL+ D Sbjct 333 RAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEETRFPRTLSPEAKSLLAGLLKKD 392 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 +R G + ++ +H +FA+ +W + +RK+ PF P+ DT FDD Sbjct 393 PKQRLGGGPDDAQEVMSHGFFASINWQDVTERKLSPPFKPQVTSEIDTRYFDD 445 >Q01314.2 RecName: Full=RAC-alpha serine/threonine-protein kinase; AltName: Full=Protein kinase B; Short=PKB; AltName: Full=Protein kinase B alpha; Short=PKB alpha; AltName: Full=RAC-PK-alpha [Bos taurus] Length=480 Score = 269 bits (687), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 133/294 (45%), Positives = 187/294 (64%), Gaps = 4/294 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ F+ +K LG G+FG+V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ Sbjct 147 MNDFEYLKLLGKGTFGKVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSR 206 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L++SF+ + L VMEY GGE+F HL R FSE ARFY A+IV +YLHS Sbjct 207 HPFLTALKYSFQTHDRLCFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHS 266 Query 161 -LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGY 216 +++YRDLK ENL++D+ G+I++TDFG K G T T CGTPEYLAPE++ Y Sbjct 267 EKEVVYRDLKLENLMLDKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDY 326 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 +AVDWW LGV++YEM G PF+ +++E I+ ++RFP S + K LL LL+ Sbjct 327 GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEEIRFPRTLSPEAKSLLSGLLKK 386 Query 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 D +R G +I H++FA+ W +Y++K+ PF P+ DT FD+ Sbjct 387 DPKQRLGGGSEDAKEIMQHRFFASIVWQDVYEKKLSPPFKPQVTSETDTRYFDE 440 >P31750.2 RecName: Full=RAC-alpha serine/threonine-protein kinase; AltName: Full=AKT1 kinase; AltName: Full=Protein kinase B; Short=PKB; AltName: Full=Protein kinase B alpha; Short=PKB alpha; AltName: Full=Proto-oncogene c-Akt; AltName: Full=RAC-PK-alpha; AltName: Full=Thymoma viral proto-oncogene [Mus musculus] Length=480 Score = 269 bits (687), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 141/337 (42%), Positives = 202/337 (60%), Gaps = 20/337 (6%) Query 14 ESVKEFLAKAKEEFLK-KWESPSQNTA---------------QLDHFDRIKTLGTGSFGR 57 ++V + L + +EE + + SPS N+ ++ F+ +K LG G+FG+ Sbjct 104 QTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGK 163 Query 58 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL 117 V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ PFL L++SF+ + L Sbjct 164 VILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRL 223 Query 118 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID 176 VMEY GGE+F HL R FSE ARFY A+IV +YLHS +++YRDLK ENL++D Sbjct 224 CFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD 283 Query 177 QQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 233 + G+I++TDFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM Sbjct 284 KDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMM 343 Query 234 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIK 293 G PF+ +++E I+ ++RFP + K LL LL+ D T+R G +I Sbjct 344 CGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 403 Query 294 NHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 H++FA W +Y++K+ PF P+ DT FD+ Sbjct 404 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDE 440 >P31748.1 RecName: Full=AKT kinase-transforming protein [AKT8 murine leukemia virus] Length=501 Score = 269 bits (688), Expect = 3e-85, Method: Compositional matrix adjust. Identities = 141/337 (42%), Positives = 202/337 (60%), Gaps = 20/337 (6%) Query 14 ESVKEFLAKAKEEFLK-KWESPSQNTA---------------QLDHFDRIKTLGTGSFGR 57 ++V + L + +EE + + SPS N+ ++ F+ +K LG G+FG+ Sbjct 125 QTVADGLKRQEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGK 184 Query 58 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL 117 V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ PFL L++SF+ + L Sbjct 185 VILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRL 244 Query 118 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID 176 VMEY GGE+F HL R FSE ARFY A+IV +YLHS +++YRDLK ENL++D Sbjct 245 CFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD 304 Query 177 QQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 233 + G+I++TDFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM Sbjct 305 KDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMM 364 Query 234 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIK 293 G PF+ +++E I+ ++RFP + K LL LL+ D T+R G +I Sbjct 365 CGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIM 424 Query 294 NHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 H++FA W +Y++K+ PF P+ DT FD+ Sbjct 425 QHRFFANIVWQDVYEKKLSPPFKPQVTSETDTRYFDE 461 >Q60823.1 RecName: Full=RAC-beta serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-2; AltName: Full=Protein kinase B beta; Short=PKB beta; AltName: Full=RAC-PK-beta [Mus musculus] Length=481 Score = 268 bits (685), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 128/293 (44%), Positives = 186/293 (63%), Gaps = 3/293 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K TG +YAMKIL K+ ++ ++ HT+ E R+LQ Sbjct 149 MNDFDYLKLLGKGTFGKVILVREKATGRYYAMKILRKEVIIAKDEVAHTVTESRVLQNTR 208 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L+++F+ + L VMEY GGE+F HL R F+E ARFY A+IV EYLHS Sbjct 209 HPFLTALKYAFQTHDRLCFVMEYANGGELFFHLSRERVFTEDRARFYGAEIVSALEYLHS 268 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYN 217 D++YRD+K ENL++D+ G+I++TDFG K G T T CGTPEYLAPE++ Y Sbjct 269 RDVVYRDIKLENLMLDKDGHIKITDFGLCKEGISDGATMKTFCGTPEYLAPEVLEDNDYG 328 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ ++RFP + K LL LL+ D Sbjct 329 RAVDWWGLGVVMYEMMCGRLPFYNQDHERLFELILMEEIRFPRTLGPEAKSLLAGLLKKD 388 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 +R G + ++ H++F + +W + Q+K+ PF P+ DT FDD Sbjct 389 PKQRLGGGPSDAKEVMEHRFFLSINWQDVVQKKLLPPFKPQVTSEVDTRYFDD 441 >Q9Y243.1 RecName: Full=RAC-gamma serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma; AltName: Full=STK-2 [Homo sapiens] Length=479 Score = 268 bits (685), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 132/307 (43%), Positives = 188/307 (61%), Gaps = 4/307 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K +G +YAMKIL K+ ++ ++ HTL E R+L+ Sbjct 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L++SF+ L VMEYV GGE+F HL R FSE RFY A+IV +YLHS Sbjct 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYN 217 ++YRDLK ENL++D+ G+I++TDFG K T CGTPEYLAPE++ Y Sbjct 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ ++FP SSD K LL LL D Sbjct 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEI 336 KR G + +I H +F+ +W +Y +K+ PF P+ DT FD ++ + I Sbjct 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444 Query 337 RVSINEK 343 ++ EK Sbjct 445 TITPPEK 451 >P34103.2 RecName: Full=Protein kinase 4 [Dictyostelium discoideum] Length=992 Score = 280 bits (715), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 135/306 (44%), Positives = 199/306 (65%), Gaps = 4/306 (1%) Query 37 NTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96 N+ +L F LG+GSF +V L +H + + MKIL++ K+++L+Q H NEK++L Sbjct 672 NSCKLSDFKLFDLLGSGSFAKVRLCQHIPSERLFCMKILNQNKIIRLRQEVHVCNEKQVL 731 Query 97 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156 + PF+VKL +FKD+ LY + E++PGGE+F ++R G S + YAA+IVL E Sbjct 732 MLTDNPFIVKLYSTFKDDRYLYFLQEFIPGGELFDYIRANGSLSLYVTQIYAAEIVLALE 791 Query 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGY 216 YLH+ D+IYRDLKPENLLIDQ G+I++TDFGFAKR+ T ++CGTPEY+APEI+ G+ Sbjct 792 YLHNQDIIYRDLKPENLLIDQYGHIKLTDFGFAKRITENTKSMCGTPEYIAPEILSGHGH 851 Query 217 NKAVDWWALGVLIYEMAAGYPPFFAD-QPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQ 275 K+ DWW+LG+LIYEM G PPF ++ I+ I +++ P +DL+ L+ Sbjct 852 GKSADWWSLGILIYEMLVGVPPFVSEGSQNDIFRLIREARIQVPPEVDQVARDLIEKLVV 911 Query 276 VDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEE 335 D+ KR G+L+ G+ DIKNH +F +W +I R+ AP P+ + P D+ +EE+ Sbjct 912 TDVEKRLGSLEGGIEDIKNHPFFGAINWNSIQNRE-SAPLKPRIR-PLKHHLMDERDEED 969 Query 336 IRVSIN 341 R+S N Sbjct 970 -RISAN 974 >Q9WUA6.1 RecName: Full=RAC-gamma serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma [Mus musculus] Length=479 Score = 268 bits (685), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 132/307 (43%), Positives = 188/307 (61%), Gaps = 4/307 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K +G +YAMKIL K+ ++ ++ HTL E R+L+ Sbjct 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L++SF+ L VMEYV GGE+F HL R FSE RFY A+IV +YLHS Sbjct 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYN 217 ++YRDLK ENL++D+ G+I++TDFG K T CGTPEYLAPE++ Y Sbjct 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ ++FP SSD K LL LL D Sbjct 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEI 336 KR G + +I H +F+ +W +Y +K+ PF P+ DT FD ++ + I Sbjct 385 PNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444 Query 337 RVSINEK 343 ++ EK Sbjct 445 TITPPEK 451 >Q63484.2 RecName: Full=RAC-gamma serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-3; AltName: Full=Protein kinase B gamma; Short=PKB gamma; AltName: Full=RAC-PK-gamma [Rattus norvegicus] Length=479 Score = 267 bits (682), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 132/307 (43%), Positives = 188/307 (61%), Gaps = 4/307 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 ++ FD +K LG G+FG+V+LV+ K +G +YAMKIL K+ ++ ++ HTL E R+L+ Sbjct 145 MNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILKKEVIIAKDEVAHTLTESRVLKNTR 204 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL L++SF+ L VMEYV GGE+F HL R FSE RFY A+IV +YLHS Sbjct 205 HPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRERVFSEDRTRFYGAEIVSALDYLHS 264 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAPEIILSKGYN 217 ++YRDLK ENL++D+ G+I++TDFG K T CGTPEYLAPE++ Y Sbjct 265 GKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDAATMKTFCGTPEYLAPEVLEDNDYG 324 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW LGV++YEM G PF+ +++E I+ ++FP SSD K LL LL D Sbjct 325 RAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILMEDIKFPRTLSSDAKSLLSGLLIKD 384 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEI 336 KR G + +I H +F+ +W +Y +K+ PF P+ DT FD ++ + I Sbjct 385 PNKRLGGGPDDPKEIMRHSFFSGVNWQDVYDKKLVPPFKPQVTSETDTRYFDEEFTAQTI 444 Query 337 RVSINEK 343 ++ EK Sbjct 445 TITPPEK 451 >P31749.2 RecName: Full=RAC-alpha serine/threonine-protein kinase; AltName: Full=Protein kinase B; Short=PKB; AltName: Full=Protein kinase B alpha; Short=PKB alpha; AltName: Full=Proto-oncogene c-Akt; AltName: Full=RAC-PK-alpha [Homo sapiens] Length=480 Score = 266 bits (681), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 141/337 (42%), Positives = 201/337 (60%), Gaps = 20/337 (6%) Query 14 ESVKEFLAKAKEEFLK-KWESPSQNTA---------------QLDHFDRIKTLGTGSFGR 57 ++V + L K +EE + + SPS N+ ++ F+ +K LG G+FG+ Sbjct 104 QTVADGLKKQEEEEMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGK 163 Query 58 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL 117 V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ PFL L++SF+ + L Sbjct 164 VILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRL 223 Query 118 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLID 176 VMEY GGE+F HL R FSE ARFY A+IV +YLHS +++YRDLK ENL++D Sbjct 224 CFVMEYANGGELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLD 283 Query 177 QQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 233 + G+I++TDFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM Sbjct 284 KDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMM 343 Query 234 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIK 293 G PF+ +++E I+ ++RFP + K LL LL+ D +R G +I Sbjct 344 CGRLPFYNQDHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPKQRLGGGSEDAKEIM 403 Query 294 NHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 H++FA W +Y++K+ PF P+ DT FD+ Sbjct 404 QHRFFAGIVWQHVYEKKLSPPFKPQVTSETDTRYFDE 440 >Q98TY9.1 RecName: Full=RAC-alpha serine/threonine-protein kinase; AltName: Full=Protein kinase Akt-1; Short=xAkt; AltName: Full=Protein kinase B, alpha; Short=PKB alpha; AltName: Full=RAC-PK-alpha [Xenopus laevis] Length=481 Score = 266 bits (681), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 142/338 (42%), Positives = 202/338 (60%), Gaps = 21/338 (6%) Query 14 ESVKEFLAKAKEEFL--KKWESPSQNTA---------------QLDHFDRIKTLGTGSFG 56 + V + L K +EE + + +SPS N+ ++ F+ +K LG G+FG Sbjct 104 QHVADNLKKQEEEMMEVRSGDSPSDNSGAEEMEVSHSKPKHKVTMNEFEYLKLLGKGTFG 163 Query 57 RVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSN 116 +V+LVK K TG +YAMKIL K+ +V ++ HTL E R+LQ PFL L++SF+ + Sbjct 164 KVILVKEKATGRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDR 223 Query 117 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS-LDLIYRDLKPENLLI 175 L VMEY GGE+F HL R FSE ARFY A+IV +YLHS +++YRDLK ENL++ Sbjct 224 LCFVMEYANGGELFFHLSRERIFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLML 283 Query 176 DQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEM 232 D+ G+I++TDFG K G T T CGTPEYLAPE++ Y +AVDWW LGV++YEM Sbjct 284 DKDGHIKITDFGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEM 343 Query 233 AAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDI 292 G PF+ +++E I+ ++RFP + K LL LL+ D +R G + +I Sbjct 344 MCGRLPFYNQDHEKLFELILMEEIRFPRTLLPEAKSLLSGLLKKDPKQRLGGGPDDAKEI 403 Query 293 KNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDD 330 HK+FA W +Y++K+ PF P+ DT FD+ Sbjct 404 MQHKFFAGIVWQDVYEKKLVPPFKPQVTSETDTRYFDE 441 >Q9XTG7.1 RecName: Full=Serine/threonine-protein kinase akt-2; AltName: Full=Protein kinase B akt-2; Short=PKB akt-2 [Caenorhabditis elegans] Length=528 Score = 266 bits (679), Expect = 1e-83, Method: Compositional matrix adjust. Identities = 126/301 (42%), Positives = 188/301 (62%), Gaps = 3/301 (1%) Query 32 ESPSQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLN 91 E P +NT +D FD +K LG G+FG+V+L + K + YA+KI+ K+ VV ++ HTL Sbjct 168 EVPRKNTVTMDDFDFLKVLGQGTFGKVILCREKSSDKLYAIKIIRKEMVVDRSEVAHTLT 227 Query 92 EKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 E R+L A PFL L++SF+ ++ VME+ GGE+F+HL+R FSE RFY ++I Sbjct 228 ENRVLYACVHPFLTLLKYSFQAQYHICFVMEFANGGELFTHLQRCKTFSEARTRFYGSEI 287 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAP 208 +L YLH +++YRD+K ENLL+D+ G+I++TDFG K + +T T CGTPEYLAP Sbjct 288 ILALGYLHHRNIVYRDMKLENLLLDRDGHIKITDFGLCKEEIKYGDKTSTFCGTPEYLAP 347 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E+I Y+++VDWW +GV++YEM G PF A + +++E I + ++FP+ S + Sbjct 348 EVIEDIDYDRSVDWWGVGVVMYEMMCGRLPFSAKENGKLFELITTCDLKFPNRLSPEAVT 407 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 LL LL+ KR G + ++ ++F DW A +++VE PF P DTS F Sbjct 408 LLSGLLERVPAKRLGAGPDDAREVSRAEFFKDVDWEATLRKEVEPPFKPNVMSETDTSFF 467 Query 329 D 329 D Sbjct 468 D 468 >P11792.3 RecName: Full=Serine/threonine-protein kinase SCH9 [Saccharomyces cerevisiae S288C] Length=824 Score = 271 bits (692), Expect = 7e-83, Method: Compositional matrix adjust. Identities = 136/292 (47%), Positives = 197/292 (67%), Gaps = 7/292 (2%) Query 44 FDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV---N 100 F+ ++ LG G+FG+V VK K+T YAMK+L K+ +VK +I HT+ E+ IL + Sbjct 412 FEVLRLLGKGTFGQVYQVKKKDTQRIYAMKVLSKKVIVKKNEIAHTIGERNILVTTASKS 471 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PF+V L+FSF+ ++LY+V +Y+ GGE+F HL++ GRFSE A+FY A++VL E+LH Sbjct 472 SPFIVGLKFSFQTPTDLYLVTDYMSGGELFWHLQKEGRFSEDRAKFYIAELVLALEHLHD 531 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKGRTWTLCGTPEYLAPEIILSK-GYNK 218 D++YRDLKPEN+L+D G I + DFG +K +K RT T CGT EYLAPE++L + GY K Sbjct 532 NDIVYRDLKPENILLDANGNIALCDFGLSKADLKDRTNTFCGTTEYLAPELLLDETGYTK 591 Query 219 AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSH-FSSDLKDLLRNLLQVD 277 VD+W+LGVLI+EM G+ PFFA+ ++Y+KI GKV+FP S + + ++ LL + Sbjct 592 MVDFWSLGVLIFEMCCGWSPFFAENNQKMYQKIAFGKVKFPRDVLSQEGRSFVKGLLNRN 651 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 R G + +G +++ H +FA DW A+ Q+K+ PF P DTSNFD Sbjct 652 PKHRLGAIDDG-RELRAHPFFADIDWEALKQKKIPPPFKPHLVSETDTSNFD 702 >Q8INB9.3 RecName: Full=RAC serine/threonine-protein kinase; Short=DAkt; Short=DRAC-PK; Short=Dakt1; AltName: Full=Akt; AltName: Full=Protein kinase B; Short=PKB [Drosophila melanogaster] Length=611 Score = 262 bits (669), Expect = 2e-81, Method: Compositional matrix adjust. Identities = 130/309 (42%), Positives = 193/309 (62%), Gaps = 4/309 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 L++F+ +K LG G+FG+V+L + K T YA+KIL K+ +++ ++ HTL E R+L++ N Sbjct 263 LENFEFLKVLGKGTFGKVILCREKATAKLYAIKILKKEVIIQKDEVAHTLTESRVLKSTN 322 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PFL+ L++SF+ N L VM+YV GGE+F HL F+E RFY A+I+ YLHS Sbjct 323 HPFLISLKYSFQTNDRLCFVMQYVNGGELFWHLSHERIFTEDRTRFYGAEIISALGYLHS 382 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGRTW-TLCGTPEYLAPEIILSKGYN 217 +IYRDLK ENLL+D+ G+I+V DFG K GRT T CGTPEYLAPE++ Y Sbjct 383 QGIIYRDLKLENLLLDKDGHIKVADFGLCKEDITYGRTTKTFCGTPEYLAPEVLDDNDYG 442 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVD 277 +AVDWW GV++YEM G PF+ ++ I+ +V+FP + + + K+LL LL D Sbjct 443 QAVDWWGTGVVMYEMICGRLPFYNRDHDVLFTLILVEEVKFPRNITDEAKNLLAGLLAKD 502 Query 278 LTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DYEEEEI 336 KR G K+ V +I+ H +FA+ +W + +K+ PF P+ DT FD ++ E + Sbjct 503 PKKRLGGGKDDVKEIQAHPFFASINWTDLVLKKIPPPFKPQVTSDTDTRYFDKEFTGESV 562 Query 337 RVSINEKCG 345 ++ + G Sbjct 563 ELTPPDPTG 571 >Q9NAH6.2 RecName: Full=Ribosomal protein S6 kinase beta [Caenorhabditis elegans] Length=550 Score = 260 bits (665), Expect = 3e-81, Method: Compositional matrix adjust. Identities = 125/293 (43%), Positives = 192/293 (66%), Gaps = 7/293 (2%) Query 44 FDRIKTLGTGSFGRVMLVKH---KETGNHYAMKILDKQKVVK-LKQIEHTLNEKRILQAV 99 F +K LG G +G+V V+ + G +AMK+L K +V+ K HT E+ IL+AV Sbjct 83 FQLLKVLGKGGYGKVFQVRKTTGSDNGQIFAMKVLQKATIVRNQKDTAHTKAERNILEAV 142 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 PF+ L ++F+ LY+++EY+ GGE+F HL R G F E A+FY ++IV++ E+LH Sbjct 143 KSPFICDLLYAFQTGGKLYLILEYLSGGELFMHLEREGMFMENVAKFYLSEIVVSLEHLH 202 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR-VKG--RTWTLCGTPEYLAPEIILSKGY 216 +IYRDLKPEN+L+D G++++TDFG K ++G +T T CGT EY+APEI++ G+ Sbjct 203 QQGIIYRDLKPENILLDAYGHVKLTDFGLCKEEIEGDQKTHTFCGTIEYMAPEILMRCGH 262 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 KAVDWW+LG L+++M G PPF A+ + +KI+ G++ P++ S++ +DL++ LL+ Sbjct 263 GKAVDWWSLGALMFDMLTGGPPFTAENRRKTIDKILKGRLTLPAYLSNEARDLIKKLLKR 322 Query 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 + R G + +IK+H +F TTDW +Y R++EAPF P + DTS FD Sbjct 323 HVDTRLGAGLSDAEEIKSHAFFKTTDWNLVYARQLEAPFKPNIENDEDTSLFD 375 >Q8MYF1.1 RecName: Full=Probable serine/threonine-protein kinase DDB_G0277449 [Dictyostelium discoideum] Length=456 Score = 255 bits (652), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 123/296 (42%), Positives = 184/296 (62%), Gaps = 5/296 (2%) Query 37 NTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRIL 96 N+ L +F +G G FG+V V H +T YA+K++ K ++ K + +TL EK IL Sbjct 121 NSINLSNFIIKHLVGKGGFGKVFQVVHVDTQKVYALKVIKKNHIIAKKSVVNTLAEKDIL 180 Query 97 QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156 + ++ PF+V L ++F++ LY+VM++V GG++F HL++ FSE RFY A+++L E Sbjct 181 KKISHPFIVNLHYAFQNEKKLYLVMDFVNGGQLFYHLQKEAIFSEDQVRFYMAELILALE 240 Query 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIILS 213 +LH ++++RDLKPEN+L+D QG+ +TDFG AK + T++ GT EY+APE+I Sbjct 241 HLHDSNIVHRDLKPENILLDSQGHCILTDFGLAKLEVKTNNETFSFAGTLEYMAPEMIQH 300 Query 214 KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 273 KAVDWW++G+L+Y+M G PPF + EKI+S K +FP SS + L+ L Sbjct 301 ATCGKAVDWWSIGILMYDMMIGKPPFEHKNRALMQEKIISEKAKFPKFVSSSARSLINGL 360 Query 274 LQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 L D TKR G NG +IK H +F + W I +++ PF+P KG D SNFD Sbjct 361 LTKDPTKRLG--ANGAIEIKRHPFFKSIQWRKIENKEITPPFVPSTKGIDDISNFD 414 >Q03042.2 RecName: Full=cGMP-dependent protein kinase, isozyme 1; Short=cGK [Drosophila melanogaster] Length=768 Score = 263 bits (672), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 126/298 (42%), Positives = 189/298 (63%), Gaps = 6/298 (2%) Query 40 QLDHFDRIKTLGTGSFGRVMLVK--HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 +L + + TLG G FGRV LVK H++ + +A+K L K+ +V KQ EH +E+ I+ Sbjct 453 KLTDLEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQEEHIFSERHIML 512 Query 98 AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEY 157 + PF+ +L +F+D +YM++E GGE+++ LR G F + A+F ++ FEY Sbjct 513 SSRSPFICRLYRTFRDEKYVYMLLEACMGGEIWTMLRDRGSFEDNAAQFIIGCVLQAFEY 572 Query 158 LHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV--KGRTWTLCGTPEYLAPEIILSKG 215 LH+ +IYRDLKPENL++D++GY+++ DFGFAK++ +TWT CGTPEY+APEIIL+KG Sbjct 573 LHARGIIYRDLKPENLMLDERGYVKIVDFGFAKQIGTSSKTWTFCGTPEYVAPEIILNKG 632 Query 216 YNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNL 273 +++AVD+WALG+LI+E+ G PPF A P+Q Y I+ G + FP H S L++ L Sbjct 633 HDRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKGIDMIAFPKHISRWAVQLIKRL 692 Query 274 LQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDY 331 + ++R G G+ DIK HKWF DW + + + PF+ P D FD + Sbjct 693 CRDVPSERLGYQTGGIQDIKKHKWFLGFDWDGLASQLLIPPFVRPIAHPTDVRYFDRF 750 >Q54IF2.1 RecName: Full=Probable serine/threonine-protein kinase DDB_G0288795 [Dictyostelium discoideum] Length=641 Score = 259 bits (663), Expect = 4e-80, Method: Compositional matrix adjust. Identities = 127/298 (43%), Positives = 187/298 (63%), Gaps = 3/298 (1%) Query 35 SQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKR 94 S +D F ++ +G G+FG+V LVK +TG YAMK++ K K + + + HT E++ Sbjct 164 SSKKVTVDDFIFLRMIGRGAFGQVNLVKKIDTGRLYAMKVIKKDKCLNMNAVGHTFTERK 223 Query 95 ILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLT 154 +L+ PF+V L++SF+ +L MV++Y+ GGE+F H+ FSE ARFY QI+L Sbjct 224 LLKKYYHPFIVGLKYSFQTQDSLCMVLDYIGGGELFYHISERETFSEETARFYIGQIMLA 283 Query 155 FEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKGR-TWTLCGTPEYLAPEII 211 +LH +IYRDLK ENLL+D G I + D G K +G T+T+CG+PEY+APEII Sbjct 284 IGFLHEHGVIYRDLKLENLLMDLDGNICLVDLGLCKEGIQEGHVTYTMCGSPEYVAPEII 343 Query 212 LSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLR 271 GY+K+VDWWALG L YEM AG PPF+++ P ++ + I+S ++FP S + L+ Sbjct 344 NGTGYSKSVDWWALGTLFYEMIAGLPPFYSEDPHEMTKLILSSPLKFPPQISKNAASLVS 403 Query 272 NLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 LL D +KR G+ ++ V +IK H +F +W + ++V+ PF P GP D S FD Sbjct 404 LLLNRDPSKRLGSGESDVEEIKAHPFFKNVNWSKLLNKEVDPPFKPHLVGPLDLSYFD 461 >Q8R4V0.2 RecName: Full=Serine/threonine-protein kinase Sgk3; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like [Rattus norvegicus] Length=496 Score = 255 bits (652), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 130/313 (42%), Positives = 188/313 (60%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 P+ N A+ FD +K +G GSFG+V+L K K G YA+K+L K+ V+ K+ +H + E Sbjct 151 PTGNPHAKPSDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAE 210 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V+++V GGE+F HL+R F EP ARFYAA+I Sbjct 211 RNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEI 270 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAP 208 YLHS+ ++YRDLKPEN+L+D G++ +TDFG K + T T CGTPEYLAP Sbjct 271 ASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAP 330 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E+I + Y++ VDWW LG ++YEM G PPF+ ++Y+ I+ + S Sbjct 331 EVIRKQPYDRTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWS 390 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 +L LL+ + R G K +I+NH +F + W + Q+K+ PF P GP D NF Sbjct 391 ILEELLEKNRQNRLG-AKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNF 449 Query 329 DD-YEEEEIRVSI 340 D + EE + S+ Sbjct 450 DAVFTEETVPYSV 462 >P50530.2 RecName: Full=Serine/threonine-protein kinase sck1 [Schizosaccharomyces pombe 972h-] Length=696 Score = 259 bits (663), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 130/294 (44%), Positives = 189/294 (64%), Gaps = 9/294 (3%) Query 44 FDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNF-- 101 F ++ +G G+FG+V LV+ +T YAMK + K+ +V+ K++ HTL E+ IL + Sbjct 302 FTALRLIGKGTFGQVYLVRKNDTNRIYAMKKISKKLIVRKKEVTHTLGERNILVRTSLDE 361 Query 102 -PFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PF+V L+FSF+ S+LY++ +Y+ GGE+F HL+ GRF E A+FY A++VL E+LH Sbjct 362 SPFIVGLKFSFQTASDLYLITDYMSGGELFWHLQHEGRFPEQRAKFYIAELVLALEHLHK 421 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAK---RVKGRTWTLCGTPEYLAPEIIL-SKGY 216 D+IYRDLKPEN+L+D G+I + DFG +K T T CGT EYLAPE++L KGY Sbjct 422 HDIIYRDLKPENILLDADGHIALCDFGLSKANLSANATTNTFCGTTEYLAPEVLLEDKGY 481 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSH-FSSDLKDLLRNLLQ 275 K VD+W+LGVL++EM G+ PF+A Q+Y I GKVRFP SS+ + +R LL Sbjct 482 TKQVDFWSLGVLVFEMCCGWSPFYAPDVQQMYRNIAFGKVRFPKGVLSSEGRSFVRGLLN 541 Query 276 VDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 + R G + + ++K H +FA +W + ++KV+ PF P + D SNFD Sbjct 542 RNPNHRLGAVAD-TTELKEHPFFADINWDLLSKKKVQPPFKPNVQNDLDVSNFD 594 >Q9ERE3.1 RecName: Full=Serine/threonine-protein kinase Sgk3; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like [Mus musculus] Length=496 Score = 254 bits (649), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 130/313 (42%), Positives = 187/313 (60%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 P+ N A+ FD +K +G GSFG+V+L K K G YA+K+L K+ V+ K+ +H + E Sbjct 151 PTGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAE 210 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V+++V GGE+F HL+R F EP ARFYAA+I Sbjct 211 RNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEPRARFYAAEI 270 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAP 208 YLHS+ ++YRDLKPEN+L+D G++ +TDFG K + T T CGTPEYLAP Sbjct 271 ASALGYLHSIKIVYRDLKPENILLDSMGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAP 330 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E+I + Y+ VDWW LG ++YEM G PPF+ ++Y+ I+ + S Sbjct 331 EVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLNLRPGVSLTAWS 390 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 +L LL+ + R G K +I+NH +F + W + Q+K+ PF P GP D NF Sbjct 391 ILEELLEKNRQNRLG-AKEDFLEIQNHPFFESLSWTDLVQKKIPPPFNPNVAGPDDIRNF 449 Query 329 DD-YEEEEIRVSI 340 D + EE + S+ Sbjct 450 DAVFTEETVPYSV 462 >Q5R7A7.1 RecName: Full=Serine/threonine-protein kinase Sgk3; AltName: Full=Serum/glucocorticoid-regulated kinase 3 [Pongo abelii] Q96BR1.1 RecName: Full=Serine/threonine-protein kinase Sgk3; AltName: Full=Cytokine-independent survival kinase; AltName: Full=Serum/glucocorticoid-regulated kinase 3; AltName: Full=Serum/glucocorticoid-regulated kinase-like [Homo sapiens] Length=496 Score = 252 bits (644), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 131/313 (42%), Positives = 186/313 (59%), Gaps = 7/313 (2%) Query 34 PSQNT-AQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNE 92 PS N A+ FD +K +G GSFG+V+L K K G YA+K+L K+ V+ K+ +H + E Sbjct 151 PSGNPHAKPTDFDFLKVIGKGSFGKVLLAKRKLDGKFYAVKVLQKKIVLNRKEQKHIMAE 210 Query 93 KRIL-QAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQI 151 + +L + V PFLV L +SF+ LY V+++V GGE+F HL+R F E ARFYAA+I Sbjct 211 RNVLLKNVKHPFLVGLHYSFQTTEKLYFVLDFVNGGELFFHLQRERSFPEHRARFYAAEI 270 Query 152 VLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR---VKGRTWTLCGTPEYLAP 208 YLHS+ ++YRDLKPEN+L+D G++ +TDFG K + T T CGTPEYLAP Sbjct 271 ASALGYLHSIKIVYRDLKPENILLDSVGHVVLTDFGLCKEGIAISDTTTTFCGTPEYLAP 330 Query 209 EIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKD 268 E+I + Y+ VDWW LG ++YEM G PPF+ ++Y+ I+ + S Sbjct 331 EVIRKQPYDNTVDWWCLGAVLYEMLYGLPPFYCRDVAEMYDNILHKPLSLRPGVSLTAWS 390 Query 269 LLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 +L LL+ D R G K +I+NH +F + W + Q+K+ PF P GP D NF Sbjct 391 ILEELLEKDRQNRLG-AKEDFLEIQNHPFFESLSWADLVQKKIPPPFNPNVAGPDDIRNF 449 Query 329 DD-YEEEEIRVSI 340 D + EE + S+ Sbjct 450 DTAFTEETVPYSV 462 >Q39030.2 RecName: Full=Serine/threonine-protein kinase AtPK2/AtPK19; AltName: Full=Ribosomal-protein S6 kinase homolog 2 [Arabidopsis thaliana] Length=471 Score = 249 bits (637), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 124/322 (39%), Positives = 197/322 (61%), Gaps = 5/322 (2%) Query 12 EQESVKEFLAKAKEEFLKKWESPSQ--NTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNH 69 E ES+KE + + +SP + ++ F+ +K +G G+FG+V V+ K+T Sbjct 106 EGESIKENDEFSGNDDTDSEKSPEEVSGVVGIEDFEVLKVVGQGAFGKVYQVRKKDTSEI 165 Query 70 YAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEM 129 YAMK++ K K+V+ E+ E+ IL ++ PF+V+L++SF+ LY+V++++ GG + Sbjct 166 YAMKVMRKDKIVEKNHAEYMKAERDILTKIDHPFIVQLKYSFQTKYRLYLVLDFINGGHL 225 Query 130 FSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFA 189 F L G F E AR Y A+IV +LH +++RDLKPEN+L+D G++ +TDFG A Sbjct 226 FFQLYHQGLFREDLARVYTAEIVSAVSHLHEKGIMHRDLKPENILMDVDGHVMLTDFGLA 285 Query 190 KRVK--GRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQI 247 K + R+ ++CGT EY+APEI+ KG++KA DWW++G+L+YEM G PPF + +I Sbjct 286 KEFEENTRSNSMCGTTEYMAPEIVRGKGHDKAADWWSVGILLYEMLTGKPPFLGSKG-KI 344 Query 248 YEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIY 307 +KIV K++ P S++ LL+ LLQ + +R G+ +G +IK HKWF +W + Sbjct 345 QQKIVKDKIKLPQFLSNEAHALLKGLLQKEPERRLGSGPSGAEEIKKHKWFKAINWKKLE 404 Query 308 QRKVEAPFIPKFKGPGDTSNFD 329 R+V+ F P G +NFD Sbjct 405 AREVQPSFKPAVSGRQCIANFD 426 >P24723.4 RecName: Full=Protein kinase C eta type; AltName: Full=PKC-L; AltName: Full=nPKC-eta [Homo sapiens] Length=683 Score = 254 bits (650), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 132/315 (42%), Positives = 197/315 (63%), Gaps = 7/315 (2%) Query 35 SQNTAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKR 94 S N +D+F+ I+ LG GSFG+VML + KETG+ YA+K+L K +++ +E T+ EKR Sbjct 346 SSNRLGIDNFEFIRVLGKGSFGKVMLARVKETGDLYAVKVLKKDVILQDDDVECTMTEKR 405 Query 95 ILQ-AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVL 153 IL A N PFL +L F+ L+ VME+V GG++ H+++ RF E ARFYAA+I+ Sbjct 406 ILSLARNHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIIS 465 Query 154 TFEYLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEI 210 +LH +IYRDLK +N+L+D +G+ ++ DFG K G T T CGTP+Y+APEI Sbjct 466 ALMFLHDKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEI 525 Query 211 ILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLL 270 + Y AVDWWA+GVL+YEM G+ PF A+ ++E I++ +V +P+ D +L Sbjct 526 LQEMLYGPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGIL 585 Query 271 RNLLQVDLTKRFGNL-KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 ++ + + T R G+L + G + I H +F DW + R++E PF P+ K D SNFD Sbjct 586 KSFMTKNPTMRLGSLTQGGEHAILRHPFFKEIDWAQLNHRQIEPPFRPRIKSREDVSNFD 645 Query 330 -DY-EEEEIRVSINE 342 D+ +EE + I+E Sbjct 646 PDFIKEEPVLTPIDE 660 >P32023.3 RecName: Full=cGMP-dependent protein kinase, isozyme 2 forms cD5/T2; Short=cGK; AltName: Full=Foraging protein [Drosophila melanogaster] Length=934 Score = 259 bits (661), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 122/287 (43%), Positives = 191/287 (67%), Gaps = 5/287 (2%) Query 47 IKTLGTGSFGRVMLVK-HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV 105 I TLG G FGRV LV+ + ++ +A+K + K ++V+ +Q +H ++EK I+ N F+V Sbjct 626 IATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIV 685 Query 106 KLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 165 KL +FKD LYM+ME GGE+++ LR G F + RFY A +V F+YLHS ++IY Sbjct 686 KLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIY 745 Query 166 RDLKPENLLIDQQGYIQVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWW 223 RDLKPENLL++++GY+++ DFGFAK+++ GR TWT CGTPEY+APE+IL++G++ + D+W Sbjct 746 RDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYW 805 Query 224 ALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLLQVDLTKR 281 +LGVL++E+ G PPF P++ Y I+ G + FP + + + +L++ L + + +R Sbjct 806 SLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAER 865 Query 282 FGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 G + G+++I+ HKWF W + +E P P K DT+NF Sbjct 866 LGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNF 912 >Q64617.1 RecName: Full=Protein kinase C eta type; AltName: Full=PKC-L; AltName: Full=nPKC-eta [Rattus norvegicus] Length=683 Score = 253 bits (647), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 130/309 (42%), Positives = 196/309 (63%), Gaps = 7/309 (2%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AV 99 +D+F+ I+ LG GSFG+VML + KETG YA+K+L K +++ +E T+ EKRIL A Sbjct 352 IDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 N PFL +L F+ L+ VME+V GG++ H+++ RF E ARFYAA+I+ +LH Sbjct 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 471 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216 +IYRDLK +N+L+D +G+ ++ DFG K G T T CGTP+Y+APEI+ Y Sbjct 472 EKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 531 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 AVDWWA+GVL+YEM G+ PF A+ ++E I++ +V +P+ D +L++ + Sbjct 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 591 Query 277 DLTKRFGNL-KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DY-EE 333 + T R G+L + G ++I H +F DW+ + R++E PF P+ K D SNFD D+ +E Sbjct 592 NPTMRLGSLTQGGEHEILRHPFFKEIDWVQLNHRQLEPPFRPRIKSREDVSNFDPDFIKE 651 Query 334 EEIRVSINE 342 E + I+E Sbjct 652 EPVLTPIDE 660 >P23298.2 RecName: Full=Protein kinase C eta type; AltName: Full=PKC-L; AltName: Full=nPKC-eta [Mus musculus] Length=683 Score = 252 bits (643), Expect = 8e-77, Method: Compositional matrix adjust. Identities = 130/309 (42%), Positives = 195/309 (63%), Gaps = 7/309 (2%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ-AV 99 +D+F+ I+ LG GSFG+VML + KETG YA+K+L K +++ +E T+ EKRIL A Sbjct 352 IDNFEFIRVLGKGSFGKVMLARIKETGELYAVKVLKKDVILQDDDVECTMTEKRILSLAR 411 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 N PFL +L F+ L+ VME+V GG++ H+++ RF E ARFYAA+I+ +LH Sbjct 412 NHPFLTQLFCCFQTPDRLFFVMEFVNGGDLMFHIQKSRRFDEARARFYAAEIISALMFLH 471 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKR--VKG-RTWTLCGTPEYLAPEIILSKGY 216 +IYRDLK +N+L+D +G+ ++ DFG K G T T CGTP+Y+APEI+ Y Sbjct 472 EKGIIYRDLKLDNVLLDHEGHCKLADFGMCKEGICNGVTTATFCGTPDYIAPEILQEMLY 531 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 AVDWWA+GVL+YEM G+ PF A+ ++E I++ +V +P+ D +L++ + Sbjct 532 GPAVDWWAMGVLLYEMLCGHAPFEAENEDDLFEAILNDEVVYPTWLHEDATGILKSFMTK 591 Query 277 DLTKRFGNL-KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-DY-EE 333 + T R G+L + G ++I H +F DW + R++E PF P+ K D SNFD D+ +E Sbjct 592 NPTMRLGSLTQGGEHEILRHPFFKEIDWAQLNHRQLEPPFRPRIKSREDVSNFDPDFIKE 651 Query 334 EEIRVSINE 342 E + I+E Sbjct 652 EPVLTPIDE 660 >Q9Z1M4.1 RecName: Full=Ribosomal protein S6 kinase beta-2; Short=S6K-beta-2; Short=S6K2; AltName: Full=70 kDa ribosomal protein S6 kinase 2; AltName: Full=p70 ribosomal S6 kinase beta; Short=p70 S6 kinase beta; Short=p70 S6K-beta; Short=p70 S6KB [Mus musculus] Length=485 Score = 246 bits (629), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 120/293 (41%), Positives = 179/293 (61%), Gaps = 7/293 (2%) Query 44 FDRIKTLGTGSFGRVMLVKHKE---TGNHYAMKILDKQKVV-KLKQIEHTLNEKRILQAV 99 F+ + LG G +G+V V+ + G YAMK+L K K+V K HT E+ IL++V Sbjct 67 FELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAERNILESV 126 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 PF+V+L ++F+ LY+++E + GGE+F+HL R G F E A FY A+I L +LH Sbjct 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAPEIILSKGY 216 S +IYRDLKPEN+++ QG+I++TDFG K T T CGT EY+APEI++ G+ Sbjct 187 SHGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEILVRTGH 246 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 N+AVDWW+LG L+Y+M G PPF A+ + +KI+ GK+ P + + D +DL + L+ Sbjct 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLAKKFLKR 306 Query 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 + T+R G D++ H +F +W + R+V+ PF P + D S FD Sbjct 307 NPTQRIGGGLGDAADVQRHPFFRHINWDDLLARRVDPPFRPSLQSEEDVSQFD 359 >Q03043.3 RecName: Full=cGMP-dependent protein kinase, isozyme 2 forms cD4/T1/T3A/T3B; Short=cGK; AltName: Full=Foraging protein [Drosophila melanogaster] Length=1088 Score = 257 bits (657), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 122/287 (43%), Positives = 191/287 (67%), Gaps = 5/287 (2%) Query 47 IKTLGTGSFGRVMLVK-HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV 105 I TLG G FGRV LV+ + ++ +A+K + K ++V+ +Q +H ++EK I+ N F+V Sbjct 780 IATLGVGGFGRVELVQTNGDSSRSFALKQMKKSQIVETRQQQHIMSEKEIMGEANCQFIV 839 Query 106 KLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 165 KL +FKD LYM+ME GGE+++ LR G F + RFY A +V F+YLHS ++IY Sbjct 840 KLFKTFKDKKYLYMLMESCLGGELWTILRDKGNFDDSTTRFYTACVVEAFDYLHSRNIIY 899 Query 166 RDLKPENLLIDQQGYIQVTDFGFAKRVK-GR-TWTLCGTPEYLAPEIILSKGYNKAVDWW 223 RDLKPENLL++++GY+++ DFGFAK+++ GR TWT CGTPEY+APE+IL++G++ + D+W Sbjct 900 RDLKPENLLLNERGYVKLVDFGFAKKLQTGRKTWTFCGTPEYVAPEVILNRGHDISADYW 959 Query 224 ALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPSHFSSDLKDLLRNLLQVDLTKR 281 +LGVL++E+ G PPF P++ Y I+ G + FP + + + +L++ L + + +R Sbjct 960 SLGVLMFELLTGTPPFTGSDPMRTYNIILKGIDAIEFPRNITRNASNLIKKLCRDNPAER 1019 Query 282 FGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNF 328 G + G+++I+ HKWF W + +E P P K DT+NF Sbjct 1020 LGYQRGGISEIQKHKWFDGFYWWGLQNCTLEPPIKPAVKSVVDTTNF 1066 >P42818.1 RecName: Full=Serine/threonine-protein kinase AtPK1/AtPK6; AltName: Full=Ribosomal-protein S6 kinase homolog 1 [Arabidopsis thaliana] Length=465 Score = 245 bits (625), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 116/291 (40%), Positives = 184/291 (63%), Gaps = 3/291 (1%) Query 41 LDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVN 100 +D F+ +K +G G+FG+V V+ KET YAMK++ K +++ E+ E+ IL ++ Sbjct 131 IDDFEVMKVVGKGAFGKVYQVRKKETSEIYAMKVMRKDHIMEKNHAEYMKAERDILTKID 190 Query 101 FPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHS 160 PF+V+L++SF+ LY+V++++ GG +F L G F E AR Y A+IV +LH Sbjct 191 HPFIVQLKYSFQTKYRLYLVLDFINGGHLFFQLYHQGLFREDLARVYTAEIVSAVSHLHE 250 Query 161 LDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVK--GRTWTLCGTPEYLAPEIILSKGYNK 218 +++RDLKPEN+L+D G++ +TDFG AK + R+ ++CGT EY+APEI+ KG++K Sbjct 251 KGIMHRDLKPENILMDTDGHVMLTDFGLAKEFEENTRSNSMCGTTEYMAPEIVRGKGHDK 310 Query 219 AVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDL 278 A DWW++G+L+YEM G PPF + +I +KIV K++ P S++ +L+ LLQ + Sbjct 311 AADWWSVGILLYEMLTGKPPFLGSKG-KIQQKIVKDKIKLPQFLSNEAHAILKGLLQKEP 369 Query 279 TKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 +R G+ +G +IK HKWF +W + R+V F P+ G +NFD Sbjct 370 ERRLGSGLSGAEEIKQHKWFKGINWKKLEAREVMPSFKPEVSGRQCIANFD 420 >P34885.2 RecName: Full=Protein kinase C-like 1B; Short=PKC1B [Caenorhabditis elegans] Length=707 Score = 251 bits (641), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 130/305 (43%), Positives = 187/305 (61%), Gaps = 7/305 (2%) Query 38 TAQLDHFDRIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQ 97 T + F +K LG GSFG+VML + K T YA+KIL K +V+ +E T+ EKRIL Sbjct 372 TLSIHDFTFMKVLGKGSFGKVMLAERKGTDEVYAIKILKKDVIVQDDDVECTMCEKRILS 431 Query 98 -AVNFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFE 156 A PFL L SF+ + L+ VMEYV GG++ ++R +F E ARFYAA++ + Sbjct 432 LAAKHPFLTALHSSFQTSDRLFFVMEYVNGGDLMFQIQRARKFDESRARFYAAEVTCALQ 491 Query 157 YLHSLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKGR---TWTLCGTPEYLAPEIILS 213 +LH D+IYRDLK +N+L+D +G+ ++ DFG K + T T CGTP+Y+APEI+ Sbjct 492 FLHRNDVIYRDLKLDNILLDAEGHCRLADFGMCKEGINKDNLTSTFCGTPDYIAPEILQE 551 Query 214 KGYNKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNL 273 Y +VDWWALGVL+YEM AG PPF AD ++E I++ V +P S + ++L+ Sbjct 552 MEYGVSVDWWALGVLMYEMMAGQPPFEADNEDDLFEAILNDDVLYPVWLSKEAVNILKAF 611 Query 274 LQVDLTKRFGNL--KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD-D 330 + + KR G + + G + I+ H +F DW A+ R+V+ PF PK K D +NFD D Sbjct 612 MTKNAGKRLGCVVSQGGEDAIRAHPFFREIDWDALESRQVKPPFKPKIKSKRDANNFDSD 671 Query 331 YEEEE 335 + +EE Sbjct 672 FTKEE 676 >Q9UBS0.2 RecName: Full=Ribosomal protein S6 kinase beta-2; Short=S6K-beta-2; Short=S6K2; AltName: Full=70 kDa ribosomal protein S6 kinase 2; Short=P70S6K2; Short=p70-S6K 2; AltName: Full=S6 kinase-related kinase; Short=SRK; AltName: Full=Serine/threonine-protein kinase 14B; AltName: Full=p70 ribosomal S6 kinase beta; Short=S6K-beta; Short=p70 S6 kinase beta; Short=p70 S6K-beta; Short=p70 S6KB; Short=p70-beta [Homo sapiens] Length=482 Score = 245 bits (626), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 118/293 (40%), Positives = 181/293 (62%), Gaps = 7/293 (2%) Query 44 FDRIKTLGTGSFGRVMLVKHKE---TGNHYAMKILDKQKVVK-LKQIEHTLNEKRILQAV 99 F+ ++ LG G +G+V V+ + G YAMK+L K K+V+ K HT E+ IL++V Sbjct 67 FELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAERNILESV 126 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 PF+V+L ++F+ LY+++E + GGE+F+HL R G F E A FY A+I L +LH Sbjct 127 KHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITLALGHLH 186 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRV---KGRTWTLCGTPEYLAPEIILSKGY 216 S +IYRDLKPEN+++ QG+I++TDFG K T T CGT EY+APEI++ G+ Sbjct 187 SQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEILVRSGH 246 Query 217 NKAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQV 276 N+AVDWW+LG L+Y+M G PPF A+ + +KI+ GK+ P + + D +DL++ L+ Sbjct 247 NRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIRGKLALPPYLTPDARDLVKKFLKR 306 Query 277 DLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFD 329 + ++R G D++ H +F +W + +V+ PF P + D S FD Sbjct 307 NPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFD 359 >A8X6H1.2 RecName: Full=cGMP-dependent protein kinase egl-4; AltName: Full=Egg-laying defective protein 4 [Caenorhabditis briggsae] Length=749 Score = 251 bits (641), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 121/297 (41%), Positives = 184/297 (62%), Gaps = 6/297 (2%) Query 41 LDHFDRIKTLGTGSFGRVMLVK-HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 L + R+ TLG G FGRV LV + + YA+K L K+ +V +Q EH E+ I+ Sbjct 435 LKNVKRLATLGVGGFGRVELVCVNGDKSKTYALKALKKKHIVDTRQQEHIFAERNIMMET 494 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 + ++VKL +F+D +YM++E GGE+++ LR G F + ARFY A ++ EYLH Sbjct 495 STDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLH 554 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYN 217 +++YRDLKPEN L+ GY+++ DFGFAK++ +TWT CGTPEY++PEIIL+KG++ Sbjct 555 RKNIVYRDLKPENCLLANSGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHD 614 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPS-HFSSDLKDLLRNLL 274 +A D+WALG+ I E+ G PPF A P++ Y I+ G + P+ L++ L Sbjct 615 QAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLC 674 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDY 331 + + +R G+ GVNDI+ H+WF DW + + ++ P +PK P D +NFD+Y Sbjct 675 RDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRTKTLKPPILPKVNNPADVTNFDNY 731 >O76360.2 RecName: Full=cGMP-dependent protein kinase egl-4; AltName: Full=Egg-laying defective protein 4 [Caenorhabditis elegans] Length=780 Score = 251 bits (641), Expect = 8e-76, Method: Compositional matrix adjust. Identities = 121/297 (41%), Positives = 184/297 (62%), Gaps = 6/297 (2%) Query 41 LDHFDRIKTLGTGSFGRVMLVK-HKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAV 99 L + R+ TLG G FGRV LV + + +A+K L K+ +V +Q EH E+ I+ Sbjct 466 LKNVKRLATLGVGGFGRVELVCVNGDKAKTFALKALKKKHIVDTRQQEHIFAERNIMMET 525 Query 100 NFPFLVKLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLH 159 + ++VKL +F+D +YM++E GGE+++ LR G F + ARFY A ++ EYLH Sbjct 526 STDWIVKLYKTFRDQKFVYMLLEVCLGGELWTTLRDRGHFDDYTARFYVACVLEGLEYLH 585 Query 160 SLDLIYRDLKPENLLIDQQGYIQVTDFGFAKRVKG--RTWTLCGTPEYLAPEIILSKGYN 217 +++YRDLKPEN L+ GY+++ DFGFAK++ +TWT CGTPEY++PEIIL+KG++ Sbjct 586 RKNIVYRDLKPENCLLANTGYLKLVDFGFAKKLASGRKTWTFCGTPEYVSPEIILNKGHD 645 Query 218 KAVDWWALGVLIYEMAAGYPPFFADQPIQIYEKIVSG--KVRFPS-HFSSDLKDLLRNLL 274 +A D+WALG+ I E+ G PPF A P++ Y I+ G + P+ L++ L Sbjct 646 QAADYWALGIYICELMLGRPPFQASDPMKTYTLILKGVDALEIPNRRIGKTATALVKKLC 705 Query 275 QVDLTKRFGNLKNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDY 331 + + +R G+ GVNDI+ H+WF DW + R ++ P +PK P D +NFD+Y Sbjct 706 RDNPGERLGSGSGGVNDIRKHRWFMGFDWEGLRSRTLKPPILPKVSNPADVTNFDNY 762 Database: Non-redundant UniProtKB/SwissProt sequences Posted date: Apr 13, 2020 3:33 AM Number of letters in database: 178,961,532 Number of sequences in database: 473,509 Lambda K H 0.320 0.138 0.413 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 473509 Number of Hits to DB: 12912990 Number of extensions: 568548 Number of successful extensions: 2451 Number of sequences better than 100: 432 Number of HSP's better than 100 without gapping: 0 Number of HSP's gapped: 1775 Number of HSP's successfully gapped: 455 Length of query: 351 Length of database: 178961532 Length adjustment: 118 Effective length of query: 233 Effective length of database: 123087470 Effective search space: 28679380510 Effective search space used: 28679380510 T: 11 A: 40 X1: 16 (7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (20.4 bits) S2: 61 (28.1 bits) ka-blk-alpha gapped: 1.9 ka-blk-alpha ungapped: 0.7916 ka-blk-alpha_v gapped: 42.6028 ka-blk-alpha_v ungapped: 4.96466 ka-blk-sigma gapped: 43.6362