alcohol biosynthetic process (GO:0046165) 114 6 .07 + 91.45 2.87E-11 5.08E-08 alcohol metabolic process (GO:0006066) 325 6 .19 + 32.08 1.30E-08 1.22E-05 amine biosynthetic process (GO:0009309) 25 2 .01 + > 100 1.06E-04 2.81E-02 ammonium ion metabolic process (GO:0097164) 23 2 .01 + > 100 9.03E-05 2.57E-02 aromatic amino acid family catabolic process (GO:0009074) 28 2 .02 + > 100 1.31E-04 3.37E-02 aromatic amino acid family metabolic process (GO:0009072) 40 4 .02 + > 100 8.41E-09 8.95E-06 aromatic compound biosynthetic process (GO:0019438) 1199 8 .69 + 11.59 4.93E-08 4.14E-05 biosynthetic process (GO:0009058) 2970 9 1.71 + 5.27 3.56E-06 1.67E-03 carboxylic acid metabolic process (GO:0019752) 885 6 .51 + 11.78 4.42E-06 2.02E-03 cellular amino acid metabolic process (GO:0006520) 289 5 .17 + 30.06 3.92E-07 2.41E-04 cellular aromatic compound metabolic process (GO:0006725) 3048 8 1.75 + 4.56 5.98E-05 1.77E-02 cellular biogenic amine biosynthetic process (GO:0042401) 24 2 .01 + > 100 9.78E-05 2.69E-02 cellular biosynthetic process (GO:0044249) 2786 9 1.60 + 5.61 2.06E-06 1.06E-03 cellular metabolic process (GO:0044237) 7742 11 4.46 + 2.47 1.47E-04 3.73E-02 cellular nitrogen compound biosynthetic process (GO:0044271) 1673 8 .96 + 8.31 6.44E-07 3.81E-04 cellular nitrogen compound metabolic process (GO:0034641) 3464 8 1.99 + 4.01 1.53E-04 3.82E-02 coenzyme biosynthetic process (GO:0009108) 136 6 .08 + 76.66 7.99E-11 1.06E-07 coenzyme metabolic process (GO:0006732) 247 6 .14 + 42.21 2.61E-09 2.97E-06 cofactor biosynthetic process (GO:0051188) 215 6 .12 + 48.49 1.16E-09 1.42E-06 cofactor metabolic process (GO:0051186) 438 6 .25 + 23.80 7.45E-08 5.94E-05 dihydrobiopterin metabolic process (GO:0051066) 2 2 .00 + > 100 1.82E-06 9.68E-04 diol biosynthetic process (GO:0034312) 19 6 .01 + > 100 1.42E-15 5.68E-12 diol metabolic process (GO:0034311) 25 6 .01 + > 100 5.91E-15 1.89E-11 drug metabolic process (GO:0017144) 493 6 .28 + 21.15 1.49E-07 1.08E-04 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) 11 2 .01 + > 100 2.36E-05 8.18E-03 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) 11 2 .01 + > 100 2.36E-05 8.01E-03 heterocycle biosynthetic process (GO:0018130) 1191 8 .69 + 11.67 4.68E-08 4.15E-05 heterocycle metabolic process (GO:0046483) 3001 8 1.73 + 4.63 5.33E-05 1.60E-02 indolalkylamine biosynthetic process (GO:0046219) 5 2 .00 + > 100 6.36E-06 2.67E-03 indolalkylamine metabolic process (GO:0006586) 17 2 .01 + > 100 5.16E-05 1.61E-02 indole-containing compound biosynthetic process (GO:0042435) 5 2 .00 + > 100 6.36E-06 2.74E-03 indole-containing compound metabolic process (GO:0042430) 24 2 .01 + > 100 9.78E-05 2.74E-02 L-phenylalanine catabolic process (GO:0006559) 11 2 .01 + > 100 2.36E-05 8.55E-03 L-phenylalanine metabolic process (GO:0006558) 11 2 .01 + > 100 2.36E-05 8.36E-03 neurotransmitter biosynthetic process (GO:0042136) 43 4 .02 + > 100 1.10E-08 1.10E-05 neurotransmitter metabolic process (GO:0042133) 89 4 .05 + 78.09 1.78E-07 1.19E-04 nitric oxide biosynthetic process (GO:0006809) 13 2 .01 + > 100 3.17E-05 1.05E-02 nitric oxide metabolic process (GO:0046209) 17 2 .01 + > 100 5.16E-05 1.58E-02 organic acid metabolic process (GO:0006082) 996 6 .57 + 10.47 8.70E-06 3.39E-03 organic cyclic compound biosynthetic process (GO:1901362) 1342 8 .77 + 10.36 1.18E-07 8.96E-05 organic cyclic compound metabolic process (GO:1901360) 3282 8 1.89 + 4.24 1.03E-04 2.79E-02 organic hydroxy compound biosynthetic process (GO:1901617) 188 8 .11 + 73.94 2.52E-14 6.70E-11 organic hydroxy compound metabolic process (GO:1901615) 469 8 .27 + 29.64 3.22E-11 4.67E-08 organic substance biosynthetic process (GO:1901576) 2892 9 1.66 + 5.41 2.84E-06 1.42E-03 organonitrogen compound biosynthetic process (GO:1901566) 1411 8 .81 + 9.85 1.74E-07 1.21E-04 oxidation-reduction process (GO:0055114) 962 6 .55 + 10.84 7.13E-06 2.92E-03 oxoacid metabolic process (GO:0043436) 976 6 .56 + 10.68 7.75E-06 3.09E-03 phenol-containing compound biosynthetic process (GO:0046189) 34 3 .02 + > 100 1.12E-06 6.15E-04 phenol-containing compound metabolic process (GO:0018958) 88 3 .05 + 59.24 1.72E-05 6.52E-03 polyol biosynthetic process (GO:0046173) 60 6 .03 + > 100 7.23E-13 1.44E-09 polyol metabolic process (GO:0019751) 116 6 .07 + 89.88 3.17E-11 5.06E-08 primary amino compound biosynthetic process (GO:1901162) 5 2 .00 + > 100 6.36E-06 2.82E-03 primary amino compound metabolic process (GO:1901160) 13 2 .01 + > 100 3.17E-05 1.03E-02 pteridine-containing compound biosynthetic process (GO:0042559) 14 6 .01 + > 100 3.12E-16 1.66E-12 pteridine-containing compound metabolic process (GO:0042558) 33 6 .02 + > 100 2.61E-14 5.96E-11 reactive nitrogen species metabolic process (GO:2001057) 21 2 .01 + > 100 7.62E-05 2.21E-02 reactive oxygen species biosynthetic process (GO:1903409) 25 2 .01 + > 100 1.06E-04 2.76E-02 regulation of neurotransmitter levels (GO:0001505) 359 4 .21 + 19.36 4.00E-05 1.28E-02 response to pain (GO:0048265) 31 2 .02 + > 100 1.59E-04 3.89E-02 serotonin biosynthetic process (GO:0042427) 3 2 .00 + > 100 3.03E-06 1.47E-03 serotonin metabolic process (GO:0042428) 10 2 .01 + > 100 2.00E-05 7.41E-03 small molecule biosynthetic process (GO:0044283) 581 6 .33 + 17.94 3.87E-07 2.47E-04 small molecule metabolic process (GO:0044281) 1718 8 .99 + 8.09 7.90E-07 4.50E-04 tetrahydrobiopterin biosynthetic process (GO:0006729) 7 6 .00 + > 100 1.38E-17 1.10E-13 tetrahydrobiopterin metabolic process (GO:0046146) 7 6 .00 + > 100 1.38E-17 2.21E-13