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Результаты поиска в Интернете
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http://www.bioinformaticscourses.com/ISB/sp2003/2TSC/
Thymidylate synthase (TS) catalyzes the final step in the de novo
synthesis of deoxy-thymidine monophosphate (dTMP)
using the substrate dUMP along with a cofactor.
As such it is the limiting irreversible step in de novo
DNA, catalyzing the conversion of dUMP to dTMP. The enzyme
is essential for regulating the balanced supply of the
4 DNA precursors in normal DNA replication.
The enzyme is an important target for certain chemotherapeutic drugs.
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http://www.tarweed.com/pgr/PGR99-082.html
Thymidylate synthase, which catalyses
the conversion of deoxyuridylate to thymidylate
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