BLASTP 2.2.28+ Reference: Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for composition-based statistics: Alejandro A. Schaffer, L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Database: mus.fasta 1,744 sequences; 1,144,840 total letters Query= sp|Q8C6L5|CGAS_MOUSE Cyclic GMP-AMP synthase OS=Mus musculus GN=Mb21d1 PE=1 SV=1 Length=507 Score E Sequences producing significant alignments: (Bits) Value sp|Q8C6L5|CGAS_MOUSE Cyclic GMP-AMP synthase OS=Mus musculus GN... 1044 0.0 sp|Q61493|DPOLZ_MOUSE DNA polymerase zeta catalytic subunit OS=... 32.3 0.089 sp|Q8BRH4|KMT2C_MOUSE Histone-lysine N-methyltransferase 2C OS=... 31.6 0.15 sp|P07934|PHKG1_MOUSE Phosphorylase b kinase gamma catalytic ch... 30.0 0.31 sp|Q62388|ATM_MOUSE Serine-protein kinase ATM OS=Mus musculus G... 28.9 1.0 sp|P45481|CBP_MOUSE CREB-binding protein OS=Mus musculus GN=Cre... 28.5 1.2 tr|Q3UHI3|Q3UHI3_MOUSE DNA-directed RNA polymerase OS=Mus muscu... 28.1 1.8 sp|O35134|RPA1_MOUSE DNA-directed RNA polymerase I subunit RPA1... 28.1 1.8 tr|Q05DK4|Q05DK4_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 1.9 tr|Q80Y46|Q80Y46_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 1.9 tr|Q05BP7|Q05BP7_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 1.9 tr|Q3TU49|Q3TU49_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 2.0 tr|Q3TUG2|Q3TUG2_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 2.0 tr|Q8BNM6|Q8BNM6_MOUSE DNA-directed RNA polymerase (Fragment) O... 27.7 2.0 tr|Q8C2X2|Q8C2X2_MOUSE DNA-directed RNA polymerase OS=Mus muscu... 27.3 2.4 tr|Q8BP95|Q8BP95_MOUSE Arginyl-tRNA--protein transferase 1 (Fra... 26.9 2.7 sp|Q9Z2A5|ATE1_MOUSE Arginyl-tRNA--protein transferase 1 OS=Mus... 26.6 4.1 tr|Q4FCQ7|Q4FCQ7_MOUSE Arginyl-tRNA--protein transferase 1 OS=M... 26.2 5.1 > sp|Q8C6L5|CGAS_MOUSE Cyclic GMP-AMP synthase OS=Mus musculus GN=Mb21d1 PE=1 SV=1 Length=507 Score = 1044 bits (2700), Expect = 0.0, Method: Compositional matrix adjust. Identities = 507/507 (100%), Positives = 507/507 (100%), Gaps = 0/507 (0%) Query 1 MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPG 60 MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPG Sbjct 1 MEDPRRRTTAPRAKKPSAKRAPTQPSRTRAHAESCGPQRGARSRRAERDGDTTEKPRAPG 60 Query 61 PRVHPARATELTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARK 120 PRVHPARATELTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARK Sbjct 61 PRVHPARATELTKDAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQPPADPEARK 120 Query 121 VVRGPSHRRGARSTGQPRAPRGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLR 180 VVRGPSHRRGARSTGQPRAPRGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLR Sbjct 121 VVRGPSHRRGARSTGQPRAPRGSRKEPDKLKKVLDKLRLKRKDISEAAETVNKVVERLLR 180 Query 181 RMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFK 240 RMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFK Sbjct 181 RMQKRESEFKGVEQLNTGSYYEHVKISAPNEFDVMFKLEVPRIELQEYYETGAFYLVKFK 240 Query 241 RIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRN 300 RIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRN Sbjct 241 RIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLIRN 300 Query 301 PEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQG 360 PEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQG Sbjct 301 PEEISVDIILALESKGSWPISTKEGLPIQGWLGTKVRTNLRREPFYLVPKNAKDGNSFQG 360 Query 361 ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS 420 ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS Sbjct 361 ETWRLSFSHTEKYILNNHGIEKTCCESSGAKCCRKECLKLMKYLLEQLKKEFQELDAFCS 420 Query 421 YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQEL 480 YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQEL Sbjct 421 YHVKTAIFHMWTQDPQDSQWDPRNLSSCFDKLLAFFLECLRTEKLDHYFIPKFNLFSQEL 480 Query 481 IDRKSKEFLSKKIEYERNNGFPIFDKL 507 IDRKSKEFLSKKIEYERNNGFPIFDKL Sbjct 481 IDRKSKEFLSKKIEYERNNGFPIFDKL 507 > sp|Q61493|DPOLZ_MOUSE DNA polymerase zeta catalytic subunit OS=Mus musculus GN=Rev3l PE=1 SV=3 Length=3122 Score = 32.3 bits (72), Expect = 0.089, Method: Compositional matrix adjust. Identities = 33/125 (26%), Positives = 51/125 (41%), Gaps = 15/125 (12%) Query 7 RTTAPRAKKPSAKRAPTQPSRTR-AHAESCGPQRGARSRRAERDGDTTEKPRAPG----- 60 +T +PR K S RA + S+ R A++ +R R++ + D +KPRA Sbjct 1158 KTVSPRVGKASRARAQVKKSKARLANSSVVTNKRNKRNQTTKLVDDGKKKPRAKQKQRAN 1217 Query 61 ----PRVHPARATELTK-----DAQPSAMDAAGATARPAVRVPQQQAILDPELPAVREPQ 111 R H A E K + P+ + T+ + +Q + PAV P Sbjct 1218 EKSLSRKHAIPADEKMKPHSEAELTPNHQSVSELTSSSGAQALSKQKEMSQTGPAVDHPL 1277 Query 112 PPADP 116 PPA P Sbjct 1278 PPAQP 1282 > sp|Q8BRH4|KMT2C_MOUSE Histone-lysine N-methyltransferase 2C OS=Mus musculus GN=Kmt2c PE=1 SV=2 Length=4903 Score = 31.6 bits (70), Expect = 0.15, Method: Compositional matrix adjust. Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 13/77 (17%) Query 363 WRLSFSHTEKYILNN------HGIEKTC--CESSGA--KCCRKECLKLMKYLLEQLKKEF 412 W L E+ +L N G + C C+ GA KCC ++C ++ Y F Sbjct 257 WSLGICQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYPCAAGAGTF 316 Query 413 QELDAF---CSYHVKTA 426 Q+ F C H+ A Sbjct 317 QDFSHFFLLCPEHIDQA 333 > sp|P07934|PHKG1_MOUSE Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform OS=Mus musculus GN=Phkg1 PE=2 SV=3 Length=388 Score = 30.0 bits (66), Expect = 0.31, Method: Compositional matrix adjust. Identities = 22/94 (23%), Positives = 44/94 (47%), Gaps = 6/94 (6%) Query 171 VNKVVERLLRRMQKRESEFKGVEQLNTGSY----YEHVKISAPNEFDVMFKLEV--PRIE 224 V+ VV R + + +E K ++ GS+ + ++ + E D++ K+ I+ Sbjct 30 VSSVVRRCIHKPTCQEYAVKIIDITGGGSFSSEEVQELREATLKEVDILQKVSGHPNIIQ 89 Query 225 LQEYYETGAFYLVKFKRIPRGNPLSHFLEGEVLS 258 L++ YET F+ + F + RG + E L+ Sbjct 90 LKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLT 123 > sp|Q62388|ATM_MOUSE Serine-protein kinase ATM OS=Mus musculus GN=Atm PE=1 SV=2 Length=3066 Score = 28.9 bits (63), Expect = 1.0, Method: Compositional matrix adjust. Identities = 13/34 (38%), Positives = 24/34 (71%), Gaps = 3/34 (9%) Query 161 RKDISEAAETVNKVVERLLRRMQKRESEFKGVEQ 194 ++ +S+ ++ NKV ER+L R+Q++ KGVE+ Sbjct 3002 KQSLSDTDQSFNKVAERVLMRLQEK---LKGVEE 3032 > sp|P45481|CBP_MOUSE CREB-binding protein OS=Mus musculus GN=Crebbp PE=1 SV=3 Length=2441 Score = 28.5 bits (62), Expect = 1.2, Method: Composition-based stats. Identities = 17/46 (37%), Positives = 24/46 (52%), Gaps = 3/46 (7%) Query 77 PSAMDAA-GATARPAVRVPQQQAILDPELPAVREPQPPADPEARKV 121 PS+M A A P + PQ Q L P++P + QPPA + R + Sbjct 477 PSSMQRAYAALGLPYMNQPQTQ--LQPQVPGQQPAQPPAHQQMRTL 520 > tr|Q3UHI3|Q3UHI3_MOUSE DNA-directed RNA polymerase OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1717 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > sp|O35134|RPA1_MOUSE DNA-directed RNA polymerase I subunit RPA1 OS=Mus musculus GN=Polr1a PE=1 SV=2 Length=1717 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q05DK4|Q05DK4_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1366 Score = 27.7 bits (60), Expect = 1.9, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q80Y46|Q80Y46_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1366 Score = 27.7 bits (60), Expect = 1.9, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q05BP7|Q05BP7_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1366 Score = 27.7 bits (60), Expect = 1.9, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q3TU49|Q3TU49_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1361 Score = 27.7 bits (60), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q3TUG2|Q3TUG2_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1424 Score = 27.7 bits (60), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q8BNM6|Q8BNM6_MOUSE DNA-directed RNA polymerase (Fragment) OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1424 Score = 27.7 bits (60), Expect = 2.0, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 494 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 525 > tr|Q8C2X2|Q8C2X2_MOUSE DNA-directed RNA polymerase OS=Mus musculus GN=Polr1a PE=2 SV=1 Length=1012 Score = 27.3 bits (59), Expect = 2.4, Method: Compositional matrix adjust. Identities = 11/32 (34%), Positives = 17/32 (53%), Gaps = 0/32 (0%) Query 60 GPRVHPARATELTKDAQPSAMDAAGATARPAV 91 GP VHP + + +D +A+ + A R AV Sbjct 516 GPNVHPGASMVINEDGSRTALSSVDAAQREAV 547 > tr|Q8BP95|Q8BP95_MOUSE Arginyl-tRNA--protein transferase 1 (Fragment) OS=Mus musculus GN=Ate1 PE=2 SV=1 Length=362 Score = 26.9 bits (58), Expect = 2.7, Method: Compositional matrix adjust. Identities = 17/61 (28%), Positives = 28/61 (46%), Gaps = 2/61 (3%) Query 239 FKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLI 298 F+ +P SH LE V+ ++ +FR +E + K + V K+ P P V+ Sbjct 103 FQSLPENA--SHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVSQFT 160 Query 299 R 299 R Sbjct 161 R 161 > sp|Q9Z2A5|ATE1_MOUSE Arginyl-tRNA--protein transferase 1 OS=Mus musculus GN=Ate1 PE=1 SV=2 Length=516 Score = 26.6 bits (57), Expect = 4.1, Method: Compositional matrix adjust. Identities = 17/61 (28%), Positives = 28/61 (46%), Gaps = 2/61 (3%) Query 239 FKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLI 298 F+ +P SH LE V+ ++ +FR +E + K + V K+ P P V+ Sbjct 257 FQSLPENA--SHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVSQFT 314 Query 299 R 299 R Sbjct 315 R 315 > tr|Q4FCQ7|Q4FCQ7_MOUSE Arginyl-tRNA--protein transferase 1 OS=Mus musculus GN=Ate1 PE=2 SV=1 Length=509 Score = 26.2 bits (56), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/61 (28%), Positives = 28/61 (46%), Gaps = 2/61 (3%) Query 239 FKRIPRGNPLSHFLEGEVLSATKMLSKFRKIIKEEVKEIKDIDVSVEKEKPGSPAVTLLI 298 F+ +P SH LE V+ ++ +FR +E + K + V K+ P P V+ Sbjct 250 FQSLPENA--SHKLEVRVVRSSPPSPQFRATFQESYQVYKRYQMVVHKDPPDKPTVSQFT 307 Query 299 R 299 R Sbjct 308 R 308 Lambda K H a alpha 0.317 0.133 0.394 0.792 4.96 Gapped Lambda K H a alpha sigma 0.267 0.0410 0.140 1.90 42.6 43.6 Effective search space used: 415383192 Database: mus.fasta Posted date: Mar 23, 2014 8:44 PM Number of letters in database: 1,144,840 Number of sequences in database: 1,744 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Neighboring words threshold: 11 Window for multiple hits: 40