Analysis Type:	PANTHER Overrepresentation Test (Released 20240807)
Annotation Version and Release Date:	GO Ontology database DOI:  10.5281/zenodo.14861039 Released 2025-02-06
Analyzed List:	upload_1 (Homo sapiens)
Reference List:	Homo sapiens (all genes in database)
Test Type:	FISHER
Correction:	FDR
GO biological process complete	Homo sapiens - REFLIST (20580)	upload_1 (67)	upload_1 (expected)	upload_1 (over/under)	upload_1 (fold Enrichment)	upload_1 (raw P-value)	upload_1 (FDR)
external encapsulating structure organization (GO:0045229)	283	53	.92	+	57.53	1.06E-87	5.26E-84
extracellular structure organization (GO:0043062)	282	53	.92	+	57.73	8.62E-88	6.41E-84
extracellular matrix organization (GO:0030198)	281	53	.91	+	57.93	7.01E-88	1.04E-83
collagen fibril organization (GO:0030199)	63	27	.21	+	 > 100	7.16E-53	2.66E-49
supramolecular fiber organization (GO:0097435)	609	27	1.98	+	13.62	4.05E-24	1.20E-20
collagen metabolic process (GO:0032963)	65	13	.21	+	61.43	1.93E-20	4.79E-17
cellular component organization (GO:0016043)	5872	53	19.12	+	2.77	1.17E-17	2.49E-14
cellular component organization or biogenesis (GO:0071840)	6083	53	19.80	+	2.68	6.31E-17	1.17E-13
skeletal system development (GO:0001501)	512	19	1.67	+	11.40	1.91E-15	3.15E-12
protein hydroxylation (GO:0018126)	18	7	.06	+	 > 100	8.68E-14	1.29E-10
cell adhesion (GO:0007155)	964	22	3.14	+	7.01	1.63E-13	2.20E-10
collagen biosynthetic process (GO:0032964)	12	6	.04	+	 > 100	8.61E-13	1.07E-09
cellular response to amino acid stimulus (GO:0071230)	85	8	.28	+	28.91	3.24E-10	3.70E-07
cellular response to acid chemical (GO:0071229)	93	8	.30	+	26.42	6.71E-10	6.65E-07
response to acid chemical (GO:0001101)	138	9	.45	+	20.03	6.48E-10	6.88E-07
connective tissue development (GO:0061448)	235	10	.77	+	13.07	4.37E-09	4.06E-06
cartilage development (GO:0051216)	176	9	.57	+	15.71	5.57E-09	4.87E-06
response to amino acid (GO:0043200)	124	8	.40	+	19.82	6.70E-09	5.54E-06
endodermal cell differentiation (GO:0035987)	46	6	.15	+	40.06	8.01E-09	6.27E-06
multicellular organism development (GO:0007275)	4001	34	13.03	+	2.61	8.96E-09	6.67E-06
animal organ morphogenesis (GO:0009887)	976	17	3.18	+	5.35	9.69E-09	6.86E-06
bone development (GO:0060348)	199	9	.65	+	13.89	1.62E-08	1.10E-05
anatomical structure development (GO:0048856)	5272	39	17.16	+	2.27	1.80E-08	1.16E-05
tissue development (GO:0009888)	1770	22	5.76	+	3.82	1.94E-08	1.20E-05
peptidyl-lysine hydroxylation (GO:0017185)	10	4	.03	+	 > 100	2.12E-08	1.26E-05
animal organ development (GO:0048513)	2884	28	9.39	+	2.98	2.46E-08	1.41E-05
endoderm formation (GO:0001706)	56	6	.18	+	32.91	2.71E-08	1.49E-05
collagen-activated tyrosine kinase receptor signaling pathway (GO:0038063)	58	6	.19	+	31.78	3.36E-08	1.78E-05
endochondral bone morphogenesis (GO:0060350)	60	6	.20	+	30.72	4.13E-08	2.12E-05
collagen-activated signaling pathway (GO:0038065)	62	6	.20	+	29.73	5.05E-08	2.50E-05
developmental process (GO:0032502)	5794	40	18.86	+	2.12	7.26E-08	3.48E-05
system development (GO:0048731)	3614	30	11.77	+	2.55	2.16E-07	1.00E-04
endoderm development (GO:0007492)	83	6	.27	+	22.20	2.94E-07	1.32E-04
skeletal system morphogenesis (GO:0048705)	230	8	.75	+	10.68	7.97E-07	3.49E-04
bone morphogenesis (GO:0060349)	100	6	.33	+	18.43	8.88E-07	3.77E-04
anatomical structure morphogenesis (GO:0009653)	2262	22	7.36	+	2.99	1.43E-06	5.92E-04
circulatory system development (GO:0072359)	940	14	3.06	+	4.57	1.59E-06	6.40E-04
basement membrane organization (GO:0071711)	29	4	.09	+	42.37	2.29E-06	8.97E-04
peptidyl-proline modification (GO:0018208)	9	3	.03	+	 > 100	2.73E-06	1.02E-03
formation of primary germ layer (GO:0001704)	121	6	.39	+	15.23	2.72E-06	1.04E-03
extracellular matrix assembly (GO:0085029)	31	4	.10	+	39.63	3.02E-06	1.10E-03
cartilage development involved in endochondral bone morphogenesis (GO:0060351)	32	4	.10	+	38.40	3.44E-06	1.22E-03
skin development (GO:0043588)	285	8	.93	+	8.62	3.94E-06	1.36E-03
ossification (GO:0001503)	292	8	.95	+	8.42	4.71E-06	1.59E-03
regulation of metabolic process (GO:0019222)	6356	5	20.69	-	.24	6.89E-06	2.28E-03
chondrocyte differentiation (GO:0002062)	85	5	.28	+	18.07	8.43E-06	2.67E-03
regulation of biosynthetic process (GO:0009889)	5260	3	17.12	-	.18	8.26E-06	2.67E-03
blood vessel development (GO:0001568)	536	10	1.74	+	5.73	8.64E-06	2.68E-03
protein maturation (GO:0051604)	538	10	1.75	+	5.71	8.92E-06	2.71E-03
hydroxylysine metabolic process (GO:0046946)	2	2	.01	+	 > 100	1.04E-05	3.04E-03
hydroxylysine biosynthetic process (GO:0046947)	2	2	.01	+	 > 100	1.04E-05	3.11E-03
vasculature development (GO:0001944)	558	10	1.82	+	5.50	1.23E-05	3.50E-03
anatomical structure formation involved in morphogenesis (GO:0048646)	988	13	3.22	+	4.04	1.51E-05	4.24E-03
gastrulation (GO:0007369)	171	6	.56	+	10.78	1.98E-05	5.45E-03
regulation of gene expression (GO:0010468)	4979	3	16.21	-	.19	2.28E-05	6.06E-03
regulation of macromolecule biosynthetic process (GO:0010556)	5086	3	16.56	-	.18	2.25E-05	6.09E-03
protein processing (GO:0016485)	186	6	.61	+	9.91	3.18E-05	8.14E-03
negative regulation of endodermal cell differentiation (GO:1903225)	3	2	.01	+	 > 100	3.13E-05	8.16E-03
cartilage condensation (GO:0001502)	20	3	.07	+	46.07	3.61E-05	9.11E-03
sensory perception of mechanical stimulus (GO:0050954)	194	6	.63	+	9.50	4.02E-05	9.96E-03
cell aggregation (GO:0098743)	22	3	.07	+	41.89	4.86E-05	1.18E-02
regulation of macromolecule metabolic process (GO:0060255)	5809	5	18.91	-	.26	5.33E-05	1.28E-02
regulation of primary metabolic process (GO:0080090)	5285	4	17.21	-	.23	5.81E-05	1.37E-02
peptidyl-proline hydroxylation (GO:0019511)	4	2	.01	+	 > 100	6.24E-05	1.45E-02
chondrocyte development (GO:0002063)	28	3	.09	+	32.91	1.02E-04	2.33E-02
tendon development (GO:0035989)	5	2	.02	+	 > 100	1.04E-04	2.34E-02
positive regulation of metabolic process (GO:0009893)	3472	1	11.30	-	.09	1.09E-04	2.41E-02
regulation of nucleobase-containing compound metabolic process (GO:0019219)	4050	2	13.19	-	.15	1.44E-04	3.14E-02
replacement ossification (GO:0036075)	32	3	.10	+	28.80	1.53E-04	3.25E-02
endochondral ossification (GO:0001958)	32	3	.10	+	28.80	1.53E-04	3.30E-02
peptidyl-amino acid modification (GO:0018193)	359	7	1.17	+	5.99	1.64E-04	3.44E-02
tube development (GO:0035295)	919	11	2.99	+	3.68	1.72E-04	3.56E-02
enzyme-linked receptor protein signaling pathway (GO:0007167)	626	9	2.04	+	4.42	1.87E-04	3.80E-02
limb joint morphogenesis (GO:0036022)	7	2	.02	+	87.76	2.17E-04	4.25E-02
sensory perception of sound (GO:0007605)	167	5	.54	+	9.20	2.13E-04	4.28E-02
regulation of endodermal cell differentiation (GO:1903224)	7	2	.02	+	87.76	2.17E-04	4.30E-02