Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.14861039 Released 2025-02-06 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO cellular component complete Homo sapiens - REFLIST (20580) upload_1 (67) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) collagen trimer (GO:0005581) 86 44 .28 + > 100 1.48E-93 2.95E-90 endoplasmic reticulum lumen (GO:0005788) 318 54 1.04 + 52.16 3.12E-87 3.11E-84 collagen-containing extracellular matrix (GO:0062023) 431 53 1.40 + 37.77 2.98E-77 1.99E-74 external encapsulating structure (GO:0030312) 568 54 1.85 + 29.20 9.39E-73 3.75E-70 extracellular matrix (GO:0031012) 567 54 1.85 + 29.25 8.50E-73 4.24E-70 complex of collagen trimers (GO:0098644) 21 20 .07 + > 100 1.61E-50 5.34E-48 endoplasmic reticulum (GO:0005783) 2102 57 6.84 + 8.33 1.48E-46 4.23E-44 basement membrane (GO:0005604) 97 22 .32 + 69.67 1.16E-35 2.88E-33 extracellular region (GO:0005576) 4302 60 14.01 + 4.28 2.09E-33 4.63E-31 extracellular space (GO:0005615) 3267 52 10.64 + 4.89 5.49E-29 1.10E-26 endomembrane system (GO:0012505) 4875 58 15.87 + 3.65 1.64E-27 2.98E-25 banded collagen fibril (GO:0098643) 12 11 .04 + > 100 2.20E-27 3.37E-25 fibrillar collagen trimer (GO:0005583) 12 11 .04 + > 100 2.20E-27 3.65E-25 network-forming collagen trimer (GO:0098642) 8 8 .03 + > 100 8.18E-21 1.09E-18 collagen network (GO:0098645) 8 8 .03 + > 100 8.18E-21 1.17E-18 membrane-enclosed lumen (GO:0031974) 5751 54 18.72 + 2.88 4.28E-19 4.74E-17 intracellular organelle lumen (GO:0070013) 5751 54 18.72 + 2.88 4.28E-19 5.02E-17 organelle lumen (GO:0043233) 5751 54 18.72 + 2.88 4.28E-19 5.34E-17 FACIT collagen trimer (GO:0005593) 7 7 .02 + > 100 2.81E-18 2.95E-16 cell periphery (GO:0071944) 6536 55 21.28 + 2.58 2.40E-17 2.39E-15 collagen type IV trimer (GO:0005587) 6 6 .02 + > 100 9.46E-16 9.00E-14 protein-containing complex (GO:0032991) 5932 51 19.31 + 2.64 1.39E-15 1.26E-13 collagen type XI trimer (GO:0005592) 5 5 .02 + > 100 3.14E-13 2.61E-11 collagen type IX trimer (GO:0005594) 5 5 .02 + > 100 3.14E-13 2.73E-11 supramolecular polymer (GO:0099081) 1076 21 3.50 + 5.99 1.31E-11 1.04E-09 supramolecular complex (GO:0099080) 1452 22 4.73 + 4.65 4.94E-10 3.79E-08 nucleus (GO:0005634) 7738 4 25.19 - .16 2.78E-09 2.06E-07 collagen type V trimer (GO:0005588) 3 3 .01 + > 100 3.30E-08 2.27E-06 basement membrane/interstitial matrix interface (GO:0140086) 3 3 .01 + > 100 3.30E-08 2.35E-06 intracellular membraneless organelle (GO:0043232) 5448 2 17.74 - .11 5.00E-07 3.22E-05 membraneless organelle (GO:0043228) 5449 2 17.74 - .11 4.99E-07 3.32E-05 cytoplasm (GO:0005737) 12351 58 40.21 + 1.44 3.80E-06 2.30E-04 intracellular membrane-bounded organelle (GO:0043231) 12368 58 40.27 + 1.44 3.80E-06 2.37E-04 membrane-bounded organelle (GO:0043227) 13442 60 43.76 + 1.37 7.79E-06 4.57E-04 interstitial hexagonal collagen network (GO:0098646) 2 2 .01 + > 100 1.04E-05 5.34E-04 collagen beaded filament (GO:0098647) 2 2 .01 + > 100 1.04E-05 5.48E-04 collagen type I trimer (GO:0005584) 2 2 .01 + > 100 1.04E-05 5.63E-04 collagen type VI trimer (GO:0005589) 2 2 .01 + > 100 1.04E-05 5.79E-04 procollagen-proline 4-dioxygenase complex (GO:0016222) 2 2 .01 + > 100 1.04E-05 5.95E-04 supramolecular fiber (GO:0099512) 1068 13 3.48 + 3.74 3.42E-05 1.71E-03 cytosol (GO:0005829) 5614 5 18.28 - .27 8.50E-05 4.14E-03 nuclear lumen (GO:0031981) 4589 3 14.94 - .20 9.56E-05 4.54E-03 intracellular organelle (GO:0043229) 13473 58 43.86 + 1.32 1.48E-04 6.85E-03 organelle (GO:0043226) 14279 60 46.49 + 1.29 1.53E-04 6.94E-03 nucleoplasm (GO:0005654) 4219 3 13.74 - .22 3.73E-04 1.65E-02 endoplasmic reticulum chaperone complex (GO:0034663) 11 2 .04 + 55.85 5.63E-04 2.45E-02 rough endoplasmic reticulum (GO:0005791) 58 3 .19 + 15.89 8.95E-04 3.80E-02 extracellular exosome (GO:0070062) 2102 16 6.84 + 2.34 9.46E-04 3.94E-02