Analysis Type:	PANTHER Overrepresentation Test (Released 20240807)
Annotation Version and Release Date:	GO Ontology database DOI:  10.5281/zenodo.14861039 Released 2025-02-06
Analyzed List:	upload_1 (Homo sapiens)
Reference List:	Homo sapiens (all genes in database)
Test Type:	FISHER
Correction:	FDR
GO molecular function complete	Homo sapiens - REFLIST (20580)	upload_1 (67)	upload_1 (expected)	upload_1 (over/under)	upload_1 (fold Enrichment)	upload_1 (raw P-value)	upload_1 (FDR)
extracellular matrix structural constituent conferring tensile strength (GO:0030020)	44	42	.14	+	 > 100	1.58E-109	8.07E-106
extracellular matrix structural constituent (GO:0005201)	168	43	.55	+	78.62	3.93E-75	1.00E-71
structural molecule activity (GO:0005198)	797	43	2.59	+	16.57	2.57E-44	4.36E-41
L-ascorbic acid binding (GO:0031418)	20	9	.07	+	 > 100	3.83E-18	4.89E-15
procollagen-proline dioxygenase activity (GO:0019798)	8	7	.03	+	 > 100	2.24E-17	2.28E-14
platelet-derived growth factor binding (GO:0048407)	11	7	.04	+	 > 100	9.17E-16	7.79E-13
peptidyl-proline dioxygenase activity (GO:0031543)	12	7	.04	+	 > 100	2.19E-15	1.60E-12
2-oxoglutarate-dependent dioxygenase activity (GO:0016706)	60	10	.20	+	51.19	4.40E-15	2.80E-12
collagen binding (GO:0005518)	72	10	.23	+	42.66	3.03E-14	1.72E-11
dioxygenase activity (GO:0051213)	93	10	.30	+	33.03	4.34E-13	2.21E-10
monosaccharide binding (GO:0048029)	74	9	.24	+	37.36	2.20E-12	1.02E-09
heparin binding (GO:0008201)	171	10	.56	+	17.96	1.98E-10	8.43E-08
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen (GO:0016705)	183	10	.60	+	16.78	3.86E-10	1.51E-07
procollagen-proline 4-dioxygenase activity (GO:0004656)	5	4	.02	+	 > 100	5.12E-10	1.63E-07
carboxylic acid binding (GO:0031406)	186	10	.61	+	16.51	4.53E-10	1.65E-07
organic acid binding (GO:0043177)	188	10	.61	+	16.34	5.03E-10	1.71E-07
vitamin binding (GO:0019842)	148	9	.48	+	18.68	1.21E-09	3.62E-07
iron ion binding (GO:0005506)	154	9	.50	+	17.95	1.72E-09	4.86E-07
glycosaminoglycan binding (GO:0005539)	241	10	.78	+	12.75	5.56E-09	1.49E-06
peptidyl-proline 4-dioxygenase activity (GO:0031545)	8	4	.03	+	 > 100	7.11E-09	1.81E-06
sulfur compound binding (GO:1901681)	271	10	.88	+	11.33	1.70E-08	4.13E-06
carbohydrate binding (GO:0030246)	279	10	.91	+	11.01	2.24E-08	5.19E-06
procollagen-proline 3-dioxygenase activity (GO:0019797)	3	3	.01	+	 > 100	3.30E-08	6.73E-06
procollagen-lysine 5-dioxygenase activity (GO:0008475)	3	3	.01	+	 > 100	3.30E-08	7.01E-06
procollagen galactosyltransferase activity (GO:0050211)	3	3	.01	+	 > 100	3.30E-08	7.31E-06
peptidyl-proline 3-dioxygenase activity (GO:0031544)	4	3	.01	+	 > 100	1.32E-07	2.49E-05
peptidyl-lysine 5-dioxygenase activity (GO:0070815)	4	3	.01	+	 > 100	1.32E-07	2.58E-05
growth factor binding (GO:0019838)	136	7	.44	+	15.81	2.95E-07	5.36E-05
metalloendopeptidase activity (GO:0004222)	110	6	.36	+	16.75	1.56E-06	2.74E-04
peptidase regulator activity (GO:0061134)	234	7	.76	+	9.19	1.09E-05	1.86E-03
protein-containing complex binding (GO:0044877)	1298	15	4.23	+	3.55	1.41E-05	2.32E-03
metallopeptidase activity (GO:0008237)	186	6	.61	+	9.91	3.18E-05	5.06E-03
catalytic activity, acting on a protein (GO:0140096)	2311	19	7.52	+	2.53	9.89E-05	1.53E-02
oxidoreductase activity (GO:0016491)	728	10	2.37	+	4.22	1.16E-04	1.68E-02
UDP-galactosyltransferase activity (GO:0035250)	29	3	.09	+	31.78	1.13E-04	1.70E-02
galactosyltransferase activity (GO:0008378)	31	3	.10	+	29.73	1.39E-04	1.97E-02
integrin binding (GO:0005178)	161	5	.52	+	9.54	1.80E-04	2.48E-02
endopeptidase inhibitor activity (GO:0004866)	169	5	.55	+	9.09	2.25E-04	3.02E-02
proteoglycan binding (GO:0043394)	37	3	.12	+	24.91	2.37E-04	3.09E-02
DNA binding (GO:0003677)	2519	0	8.20	-	 < 0.01	2.56E-04	3.26E-02
peptidase inhibitor activity (GO:0030414)	177	5	.58	+	8.68	2.79E-04	3.47E-02
serine-type endopeptidase inhibitor activity (GO:0004867)	102	4	.33	+	12.05	3.43E-04	4.16E-02