Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.14861039 Released 2025-02-06 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (6) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) estrogen biosynthetic process (GO:0006703) 11 5 .00 + > 100 9.01E-17 1.34E-12 steroid hormone biosynthetic process (GO:0120178) 32 5 .01 + > 100 3.93E-14 2.92E-10 estrogen metabolic process (GO:0008210) 39 5 .01 + > 100 1.12E-13 5.56E-10 hormone biosynthetic process (GO:0042446) 43 5 .01 + > 100 1.88E-13 6.97E-10 steroid metabolic process (GO:0008202) 257 6 .07 + 80.08 3.58E-12 1.06E-08 steroid biosynthetic process (GO:0006694) 97 5 .03 + > 100 1.25E-11 3.11E-08 hormone metabolic process (GO:0042445) 209 5 .06 + 82.06 6.13E-10 1.30E-06 steroid catabolic process (GO:0006706) 25 3 .01 + > 100 3.16E-08 5.87E-05 lipid metabolic process (GO:0006629) 1209 6 .35 + 17.02 4.06E-08 6.71E-05 androgen metabolic process (GO:0008209) 30 3 .01 + > 100 5.57E-08 8.29E-05 regulation of hormone levels (GO:0010817) 554 5 .16 + 30.96 8.15E-08 1.10E-04 lipid biosynthetic process (GO:0008610) 583 5 .17 + 29.42 1.05E-07 1.30E-04 androgen catabolic process (GO:0006710) 5 2 .00 + > 100 7.08E-07 8.10E-04 testosterone biosynthetic process (GO:0061370) 6 2 .00 + > 100 1.06E-06 1.13E-03 hormone catabolic process (GO:0042447) 12 2 .00 + > 100 4.67E-06 4.63E-03 olefinic compound biosynthetic process (GO:0120255) 13 2 .00 + > 100 5.52E-06 5.13E-03 olefinic compound metabolic process (GO:0120254) 143 3 .04 + 71.96 6.47E-06 5.66E-03 ketone biosynthetic process (GO:0042181) 30 2 .01 + > 100 3.07E-05 2.54E-02 lipid catabolic process (GO:0016042) 304 3 .09 + 33.85 6.18E-05 4.83E-02 ketone metabolic process (GO:0042180) 86 2 .03 + 79.77 2.56E-04 1.90E-01 regulation of biological quality (GO:0065008) 2968 5 .87 + 5.78 3.28E-04 2.33E-01 small molecule metabolic process (GO:0044281) 1575 4 .46 + 8.71 4.52E-04 3.06E-01 positive regulation of estradiol secretion (GO:2000866) 2 1 .00 + > 100 5.83E-04 3.77E-01 regulation of estradiol secretion (GO:2000864) 3 1 .00 + > 100 8.74E-04 5.42E-01 negative regulation of chronic inflammatory response (GO:0002677) 4 1 .00 + > 100 1.17E-03 6.93E-01 primary metabolic process (GO:0044238) 6774 6 1.97 + 3.04 1.27E-03 7.26E-01 biosynthetic process (GO:0009058) 3960 5 1.15 + 4.33 1.33E-03 7.31E-01 monoatomic ion transmembrane transport (GO:0034220) 859 0 .25 - < 0.01 1.00E00 1.00E00 respiratory burst involved in defense response (GO:0002679) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to lead ion (GO:0010288) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of chronic inflammatory response (GO:0002678) 4 0 .00 - < 0.01 1.00E00 1.00E00 heat acclimation (GO:0010286) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chronic inflammatory response (GO:0002676) 9 1 .00 + > 100 2.62E-03 1.00E00 positive regulation of acute inflammatory response (GO:0002675) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of acute inflammatory response (GO:0002674) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acute inflammatory response (GO:0002673) 46 0 .01 - < 0.01 1.00E00 1.00E00 carbohydrate transmembrane transport (GO:0034219) 58 0 .02 - < 0.01 1.00E00 1.00E00 protein hexamerization (GO:0034214) 9 0 .00 - < 0.01 1.00E00 1.00E00 quinolinate catabolic process (GO:0034213) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell anergy (GO:0002669) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell anergy (GO:0002667) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell tolerance induction (GO:0002666) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell tolerance induction (GO:0002664) 14 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of copper ion (GO:0010273) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell tolerance induction (GO:0002663) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to silver ion (GO:0010272) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell tolerance induction (GO:0002661) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peripheral tolerance induction (GO:0002660) 1 0 .00 - < 0.01 1.00E00 1.00E00 amyloid-beta formation (GO:0034205) 10 0 .00 - < 0.01 1.00E00 1.00E00 lipid translocation (GO:0034204) 58 0 .02 - < 0.01 1.00E00 1.00E00 glycolipid translocation (GO:0034203) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to oleic acid (GO:0034201) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to selenium ion (GO:0010269) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peripheral tolerance induction (GO:0002658) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin B1 (GO:0010266) 3 0 .00 - < 0.01 1.00E00 1.00E00 SCF complex assembly (GO:0010265) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction dependent upon immune response (GO:0002654) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction dependent upon immune response (GO:0002652) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction to self antigen (GO:0002651) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal cholesterol absorption (GO:0045797) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intestinal cholesterol absorption (GO:0045796) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell volume (GO:0045795) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell volume (GO:0045794) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell size (GO:0045793) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell size (GO:0045792) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction to self antigen (GO:0002649) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of central tolerance induction (GO:0002648) 1 0 .00 - < 0.01 1.00E00 1.00E00 NADH dehydrogenase complex assembly (GO:0010257) 42 0 .01 - < 0.01 1.00E00 1.00E00 endomembrane system organization (GO:0010256) 573 0 .17 - < 0.01 1.00E00 1.00E00 regulation of central tolerance induction (GO:0002646) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucose mediated signaling pathway (GO:0010255) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tolerance induction (GO:0002645) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tolerance induction (GO:0002644) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tolerance induction (GO:0002643) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle (GO:0045787) 330 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle (GO:0045786) 355 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell adhesion (GO:0045785) 496 0 .14 - < 0.01 1.00E00 1.00E00 positive regulation of bone resorption (GO:0045780) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of immunoglobulin production (GO:0002639) 57 0 .02 - < 0.01 1.00E00 1.00E00 establishment or maintenance of transmembrane electrochemical gradient (GO:0010248) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of immunoglobulin production (GO:0002638) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of immunoglobulin production (GO:0002637) 79 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of germinal center formation (GO:0002636) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of germinal center formation (GO:0002635) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of germinal center formation (GO:0002634) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bone resorption (GO:0045779) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ossification (GO:0045778) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of blood pressure (GO:0045777) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of blood pressure (GO:0045776) 53 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of axon extension (GO:0045773) 37 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of autophagosome size (GO:0045772) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell antigen processing and presentation (GO:0002625) 1 0 .00 - < 0.01 1.00E00 1.00E00 vascular transport (GO:0010232) 87 0 .03 - < 0.01 1.00E00 1.00E00 regulation of B cell antigen processing and presentation (GO:0002622) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of asymmetric cell division (GO:0045769) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of angiogenesis (GO:0045766) 169 0 .05 - < 0.01 1.00E00 1.00E00 regulation of angiogenesis (GO:0045765) 296 0 .09 - < 0.01 1.00E00 1.00E00 positive regulation of amino acid metabolic process (GO:0045764) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amino acid metabolic process (GO:0045763) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase activity (GO:0045762) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase activity (GO:0045761) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of action potential (GO:0045760) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage antigen processing and presentation (GO:0002618) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage antigen processing and presentation (GO:0002617) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to lithium ion (GO:0010226) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage antigen processing and presentation (GO:0002616) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to UV-C (GO:0010225) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to UV-B (GO:0010224) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of action potential (GO:0045759) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Toll signaling pathway (GO:0045752) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Toll signaling pathway (GO:0045751) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell antigen processing and presentation (GO:0002606) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell antigen processing and presentation (GO:0002605) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell antigen processing and presentation (GO:0002604) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to ionizing radiation (GO:0010212) 140 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903298) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hypoxia-induced intrinsic apoptotic signaling pathway (GO:1903297) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Notch signaling pathway (GO:0045747) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate secretion, neurotransmission (GO:1903296) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Notch signaling pathway (GO:0045746) 40 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of G protein-coupled receptor signaling pathway (GO:0045745) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glutamate secretion, neurotransmission (GO:1903294) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G protein-coupled receptor signaling pathway (GO:0045744) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast growth factor receptor signaling pathway (GO:0045743) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to Golgi membrane (GO:1903292) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epidermal growth factor receptor signaling pathway (GO:0045742) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of epidermal growth factor-activated receptor activity (GO:0045741) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA replication (GO:0045740) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of DNA repair (GO:0045739) 143 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of potassium ion import across plasma membrane (GO:1903288) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA repair (GO:0045738) 40 0 .01 - < 0.01 1.00E00 1.00E00 arginine catabolic process to proline (GO:0019493) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045737) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of potassium ion import (GO:1903286) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0045736) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide catabolic process (GO:1903285) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutathione peroxidase activity (GO:1903284) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutathione peroxidase activity (GO:1903282) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein catabolic process (GO:0045732) 214 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of calcium:sodium antiporter activity (GO:1903281) 1 0 .00 - < 0.01 1.00E00 1.00E00 respiratory burst (GO:0045730) 24 0 .01 - < 0.01 1.00E00 1.00E00 response to glucagon (GO:0033762) 23 0 .01 - < 0.01 1.00E00 1.00E00 cerebral cortex radially oriented cell migration (GO:0021799) 37 0 .01 - < 0.01 1.00E00 1.00E00 forebrain dorsal/ventral pattern formation (GO:0021798) 7 0 .00 - < 0.01 1.00E00 1.00E00 forebrain anterior/posterior pattern specification (GO:0021797) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex regionalization (GO:0021796) 7 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex cell migration (GO:0021795) 49 0 .01 - < 0.01 1.00E00 1.00E00 thalamus development (GO:0021794) 14 0 .00 - < 0.01 1.00E00 1.00E00 chemorepulsion of branchiomotor axon (GO:0021793) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sodium ion export across plasma membrane (GO:1903278) 11 0 .00 - < 0.01 1.00E00 1.00E00 respiratory burst after phagocytosis (GO:0045728) 4 0 .00 - < 0.01 1.00E00 1.00E00 beta-alanine biosynthetic process (GO:0019483) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translation (GO:0045727) 137 0 .04 - < 0.01 1.00E00 1.00E00 regulation of sodium ion export across plasma membrane (GO:1903276) 11 0 .00 - < 0.01 1.00E00 1.00E00 beta-alanine metabolic process (GO:0019482) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of integrin biosynthetic process (GO:0045726) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-alanine catabolic process, by transamination (GO:0019481) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen biosynthetic process (GO:0045725) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cilium assembly (GO:0045724) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of fatty acid biosynthetic process (GO:0045723) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of gluconeogenesis (GO:0045722) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of gluconeogenesis (GO:0045721) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of integrin biosynthetic process (GO:0045720) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribosome localization (GO:0033750) 12 0 .00 - < 0.01 1.00E00 1.00E00 branchiomotor neuron axon guidance (GO:0021785) 7 0 .00 - < 0.01 1.00E00 1.00E00 postganglionic parasympathetic fiber development (GO:0021784) 2 0 .00 - < 0.01 1.00E00 1.00E00 preganglionic parasympathetic fiber development (GO:0021783) 17 0 .00 - < 0.01 1.00E00 1.00E00 glial cell development (GO:0021782) 129 0 .04 - < 0.01 1.00E00 1.00E00 D-amino acid catabolic process (GO:0019478) 2 0 .00 - < 0.01 1.00E00 1.00E00 glial cell fate commitment (GO:0021781) 13 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process (GO:0019477) 4 0 .00 - < 0.01 1.00E00 1.00E00 glial cell fate specification (GO:0021780) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen biosynthetic process (GO:0045719) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process to acetyl-CoA (GO:0019474) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid biosynthetic process (GO:0045717) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of tumor necrosis factor-mediated signaling pathway (GO:1903265) 13 0 .00 - < 0.01 1.00E00 1.00E00 4-hydroxyproline metabolic process (GO:0019471) 6 0 .00 - < 0.01 1.00E00 1.00E00 4-hydroxyproline catabolic process (GO:0019470) 4 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte cell fate commitment (GO:0021779) 4 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte cell fate specification (GO:0021778) 4 0 .00 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in spinal cord motor neuron cell fate specification (GO:0021776) 2 0 .00 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in ventral spinal cord interneuron specification (GO:0021775) 3 0 .00 - < 0.01 1.00E00 1.00E00 striatal medium spiny neuron differentiation (GO:0021773) 4 0 .00 - < 0.01 1.00E00 1.00E00 olfactory bulb development (GO:0021772) 35 0 .01 - < 0.01 1.00E00 1.00E00 lateral geniculate nucleus development (GO:0021771) 1 0 .00 - < 0.01 1.00E00 1.00E00 exon-exon junction complex disassembly (GO:1903259) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycine decarboxylation via glycine cleavage system (GO:0019464) 3 0 .00 - < 0.01 1.00E00 1.00E00 ectoderm and mesoderm interaction (GO:0007499) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesoderm development (GO:0007498) 131 0 .04 - < 0.01 1.00E00 1.00E00 multi-ciliated epithelial cell differentiation (GO:1903251) 11 0 .00 - < 0.01 1.00E00 1.00E00 posterior midgut development (GO:0007497) 2 0 .00 - < 0.01 1.00E00 1.00E00 visceral mesoderm-endoderm interaction involved in midgut development (GO:0007495) 1 0 .00 - < 0.01 1.00E00 1.00E00 midgut development (GO:0007494) 12 0 .00 - < 0.01 1.00E00 1.00E00 endodermal cell fate determination (GO:0007493) 2 0 .00 - < 0.01 1.00E00 1.00E00 endoderm development (GO:0007492) 83 0 .02 - < 0.01 1.00E00 1.00E00 orbitofrontal cortex development (GO:0021769) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleus accumbens development (GO:0021768) 1 0 .00 - < 0.01 1.00E00 1.00E00 mammillary body development (GO:0021767) 1 0 .00 - < 0.01 1.00E00 1.00E00 hippocampus development (GO:0021766) 95 0 .03 - < 0.01 1.00E00 1.00E00 amygdala development (GO:0021764) 5 0 .00 - < 0.01 1.00E00 1.00E00 substantia nigra development (GO:0021762) 46 0 .01 - < 0.01 1.00E00 1.00E00 limbic system development (GO:0021761) 126 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of citrulline biosynthetic process (GO:1903249) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of citrulline biosynthetic process (GO:1903248) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process to taurine (GO:0019452) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle hypertrophy in response to stress (GO:1903244) 3 0 .00 - < 0.01 1.00E00 1.00E00 piRNA-mediated gene silencing by mRNA destabilization (GO:0140991) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle hypertrophy in response to stress (GO:1903243) 7 0 .00 - < 0.01 1.00E00 1.00E00 primary piRNA processing (GO:0140990) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle hypertrophy in response to stress (GO:1903242) 11 0 .00 - < 0.01 1.00E00 1.00E00 U2-type prespliceosome assembly (GO:1903241) 25 0 .01 - < 0.01 1.00E00 1.00E00 globus pallidus development (GO:0021759) 4 0 .00 - < 0.01 1.00E00 1.00E00 putamen development (GO:0021758) 1 0 .00 - < 0.01 1.00E00 1.00E00 caudate nucleus development (GO:0021757) 1 0 .00 - < 0.01 1.00E00 1.00E00 striatum development (GO:0021756) 22 0 .01 - < 0.01 1.00E00 1.00E00 facial nucleus development (GO:0021754) 2 0 .00 - < 0.01 1.00E00 1.00E00 pronephric nephron tubule development (GO:0039020) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process to hypotaurine (GO:0019449) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-cysteine catabolic process (GO:0019448) 4 0 .00 - < 0.01 1.00E00 1.00E00 vestibular nucleus development (GO:0021750) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte tethering or rolling (GO:1903238) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte tethering or rolling (GO:1903237) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte tethering or rolling (GO:1903236) 18 0 .01 - < 0.01 1.00E00 1.00E00 L-tryptophan catabolic process to acetyl-CoA (GO:0019442) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion-dependent exocytosis of neurotransmitter (GO:1903235) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-tryptophan catabolic process to kynurenine (GO:0019441) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-tryptophan catabolic process to indole-3-acetate (GO:0019440) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion-dependent exocytosis of neurotransmitter (GO:1903233) 4 0 .00 - < 0.01 1.00E00 1.00E00 melanosome assembly (GO:1903232) 19 0 .01 - < 0.01 1.00E00 1.00E00 pronephric nephron development (GO:0039019) 3 0 .00 - < 0.01 1.00E00 1.00E00 pattern specification involved in pronephros development (GO:0039017) 2 0 .00 - < 0.01 1.00E00 1.00E00 cochlear nucleus development (GO:0021747) 3 0 .00 - < 0.01 1.00E00 1.00E00 hypoglossal nucleus development (GO:0021743) 1 0 .00 - < 0.01 1.00E00 1.00E00 abducens nucleus development (GO:0021742) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic skeletal joint development (GO:0072498) 16 0 .00 - < 0.01 1.00E00 1.00E00 principal sensory nucleus of trigeminal nerve development (GO:0021740) 4 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal stem cell differentiation (GO:0072497) 1 0 .00 - < 0.01 1.00E00 1.00E00 disruption of cellular anatomical structure in another organism (GO:0140975) 5 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride catabolic process (GO:0019433) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of endodermal cell differentiation (GO:1903226) 3 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride biosynthetic process (GO:0019432) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of AIM2 inflammasome complex assembly (GO:0140973) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endodermal cell differentiation (GO:1903225) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of AIM2 inflammasome complex assembly (GO:0140972) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endodermal cell differentiation (GO:1903224) 7 0 .00 - < 0.01 1.00E00 1.00E00 removal of superoxide radicals (GO:0019430) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of AIM2 inflammasome complex assembly (GO:0140971) 5 0 .00 - < 0.01 1.00E00 1.00E00 AIM2 inflammasome complex assembly (GO:0140970) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA integration (GO:0015074) 17 0 .00 - < 0.01 1.00E00 1.00E00 pronephric nephron tubule morphogenesis (GO:0039008) 1 0 .00 - < 0.01 1.00E00 1.00E00 pronephric nephron morphogenesis (GO:0039007) 1 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid efflux (GO:0033700) 13 0 .00 - < 0.01 1.00E00 1.00E00 pronephric field specification (GO:0039003) 2 0 .00 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary maturation (GO:0021732) 1 0 .00 - < 0.01 1.00E00 1.00E00 methylammonium transmembrane transport (GO:0072489) 2 0 .00 - < 0.01 1.00E00 1.00E00 ammonium transmembrane transport (GO:0072488) 11 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA biosynthetic process from acetate (GO:0019427) 2 0 .00 - < 0.01 1.00E00 1.00E00 trigeminal sensory nucleus development (GO:0021730) 4 0 .00 - < 0.01 1.00E00 1.00E00 piRNA-mediated heterochromatin formation (GO:0140966) 16 0 .00 - < 0.01 1.00E00 1.00E00 secondary piRNA processing (GO:0140965) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein processing involved in protein targeting to mitochondrion (GO:1903217) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein processing involved in protein targeting to mitochondrion (GO:1903216) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein targeting to mitochondrion (GO:1903215) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of primary metabolic process (GO:0080090) 5285 0 1.54 - < 0.01 3.49E-01 1.00E00 multicellular organismal-level chemical homeostasis (GO:0140962) 80 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein targeting to mitochondrion (GO:1903214) 46 0 .01 - < 0.01 1.00E00 1.00E00 cellular detoxification of metal ion (GO:0140961) 3 0 .00 - < 0.01 1.00E00 1.00E00 podocyte apoptotic process (GO:1903210) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of the force of heart contraction by chemical signal (GO:0003099) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal water transport (GO:0003097) 8 0 .00 - < 0.01 1.00E00 1.00E00 renal sodium ion transport (GO:0003096) 16 0 .00 - < 0.01 1.00E00 1.00E00 pressure natriuresis (GO:0003095) 3 0 .00 - < 0.01 1.00E00 1.00E00 glomerular filtration (GO:0003094) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glomerular filtration (GO:0003093) 10 0 .00 - < 0.01 1.00E00 1.00E00 renal water retention (GO:0003092) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal water homeostasis (GO:0003091) 24 0 .01 - < 0.01 1.00E00 1.00E00 medullary reticular formation development (GO:0021723) 1 0 .00 - < 0.01 1.00E00 1.00E00 superior olivary nucleus maturation (GO:0021722) 2 0 .00 - < 0.01 1.00E00 1.00E00 sulfide oxidation (GO:0019418) 3 0 .00 - < 0.01 1.00E00 1.00E00 sulfur oxidation (GO:0019417) 2 0 .00 - < 0.01 1.00E00 1.00E00 target-directed miRNA degradation (GO:0140958) 4 0 .00 - < 0.01 1.00E00 1.00E00 acetate biosynthetic process (GO:0019413) 2 0 .00 - < 0.01 1.00E00 1.00E00 hindgut morphogenesis (GO:0007442) 7 0 .00 - < 0.01 1.00E00 1.00E00 foregut morphogenesis (GO:0007440) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of systemic arterial blood pressure (GO:0003085) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of systemic arterial blood pressure (GO:0003084) 15 0 .00 - < 0.01 1.00E00 1.00E00 superior olivary nucleus development (GO:0021718) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of behavioral fear response (GO:2000987) 7 0 .00 - < 0.01 1.00E00 1.00E00 dolichol biosynthetic process (GO:0019408) 4 0 .00 - < 0.01 1.00E00 1.00E00 hexitol catabolic process (GO:0019407) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ATP citrate synthase activity (GO:2000984) 1 0 .00 - < 0.01 1.00E00 1.00E00 alditol catabolic process (GO:0019405) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ATP citrate synthase activity (GO:2000983) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inner ear receptor cell differentiation (GO:2000982) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inner ear receptor cell differentiation (GO:2000981) 4 0 .00 - < 0.01 1.00E00 1.00E00 galactitol metabolic process (GO:0019402) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inner ear receptor cell differentiation (GO:2000980) 10 0 .00 - < 0.01 1.00E00 1.00E00 alditol biosynthetic process (GO:0019401) 5 0 .00 - < 0.01 1.00E00 1.00E00 alditol metabolic process (GO:0019400) 23 0 .01 - < 0.01 1.00E00 1.00E00 ectodermal digestive tract development (GO:0007439) 2 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal-epithelial cell signaling involved in lung development (GO:0060496) 1 0 .00 - < 0.01 1.00E00 1.00E00 salivary gland morphogenesis (GO:0007435) 29 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in lung development (GO:0060495) 2 0 .00 - < 0.01 1.00E00 1.00E00 lung induction (GO:0060492) 3 0 .00 - < 0.01 1.00E00 1.00E00 salivary gland development (GO:0007431) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell projection assembly (GO:0060491) 205 0 .06 - < 0.01 1.00E00 1.00E00 lateral sprouting involved in lung morphogenesis (GO:0060490) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure (GO:0003073) 107 0 .03 - < 0.01 1.00E00 1.00E00 renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure (GO:0003072) 7 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granule cell differentiation (GO:0021707) 8 0 .00 - < 0.01 1.00E00 1.00E00 renal system process involved in regulation of systemic arterial blood pressure (GO:0003071) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by neurotransmitter (GO:0003070) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of forebrain neuron differentiation (GO:2000979) 1 0 .00 - < 0.01 1.00E00 1.00E00 locus ceruleus development (GO:0021703) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of forebrain neuron differentiation (GO:2000978) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell differentiation (GO:0021702) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of forebrain neuron differentiation (GO:2000977) 5 0 .00 - < 0.01 1.00E00 1.00E00 developmental maturation (GO:0021700) 294 0 .09 - < 0.01 1.00E00 1.00E00 positive regulation of pro-B cell differentiation (GO:2000975) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of pro-B cell differentiation (GO:2000974) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pro-B cell differentiation (GO:2000973) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of detection of glucose (GO:2000972) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of detection of glucose (GO:2000970) 2 0 .00 - < 0.01 1.00E00 1.00E00 planar dichotomous subdivision of terminal units involved in lung branching morphogenesis (GO:0060489) 1 0 .00 - < 0.01 1.00E00 1.00E00 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis (GO:0060488) 1 0 .00 - < 0.01 1.00E00 1.00E00 lung epithelial cell differentiation (GO:0060487) 26 0 .01 - < 0.01 1.00E00 1.00E00 club cell differentiation (GO:0060486) 4 0 .00 - < 0.01 1.00E00 1.00E00 mesenchyme development (GO:0060485) 245 0 .07 - < 0.01 1.00E00 1.00E00 lung-associated mesenchyme development (GO:0060484) 9 0 .00 - < 0.01 1.00E00 1.00E00 sensory organ development (GO:0007423) 613 0 .18 - < 0.01 1.00E00 1.00E00 peripheral nervous system development (GO:0007422) 86 0 .03 - < 0.01 1.00E00 1.00E00 protein transport (GO:0015031) 1095 0 .32 - < 0.01 1.00E00 1.00E00 lobar bronchus development (GO:0060482) 5 0 .00 - < 0.01 1.00E00 1.00E00 lobar bronchus epithelium development (GO:0060481) 4 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0003069) 1 0 .00 - < 0.01 1.00E00 1.00E00 brain development (GO:0007420) 747 0 .22 - < 0.01 1.00E00 1.00E00 lung goblet cell differentiation (GO:0060480) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by acetylcholine (GO:0003068) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate by epinephrine (GO:0003065) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heart rate by hormone (GO:0003064) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heart rate by chemical signal (GO:0003062) 5 0 .00 - < 0.01 1.00E00 1.00E00 inhibition of non-skeletal tissue mineralization (GO:0140928) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-kynurenine transmembrane transport (GO:0140924) 1 0 .00 - < 0.01 1.00E00 1.00E00 lung cell differentiation (GO:0060479) 26 0 .01 - < 0.01 1.00E00 1.00E00 ventral midline development (GO:0007418) 6 0 .00 - < 0.01 1.00E00 1.00E00 acrosomal vesicle exocytosis (GO:0060478) 6 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system development (GO:0007417) 1021 0 .30 - < 0.01 1.00E00 1.00E00 synapse assembly (GO:0007416) 133 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of flagellated sperm motility involved in capacitation (GO:0060474) 3 0 .00 - < 0.01 1.00E00 1.00E00 axonal fasciculation (GO:0007413) 21 0 .01 - < 0.01 1.00E00 1.00E00 axon target recognition (GO:0007412) 3 0 .00 - < 0.01 1.00E00 1.00E00 axon guidance (GO:0007411) 228 0 .07 - < 0.01 1.00E00 1.00E00 cortical granule exocytosis (GO:0060471) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytosolic calcium ion concentration involved in egg activation (GO:0060470) 1 0 .00 - < 0.01 1.00E00 1.00E00 hormonal regulation of the force of heart contraction (GO:0003058) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of the force of heart contraction by chemical signal (GO:0003057) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle contraction (GO:0003056) 9 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin-mediated drinking behavior (GO:0003051) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by atrial natriuretic peptide (GO:0003050) 2 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into mitochondrion (GO:0140917) 1 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into lysosome (GO:0140916) 4 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into zymogen granule (GO:0140915) 1 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into secretory vesicle (GO:0140914) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to G1 DNA damage checkpoint signaling (GO:0072432) 1 0 .00 - < 0.01 1.00E00 1.00E00 axonogenesis (GO:0007409) 370 0 .11 - < 0.01 1.00E00 1.00E00 prevention of polyspermy (GO:0060468) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fertilization (GO:0060467) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuroblast proliferation (GO:0007406) 11 0 .00 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process, enzymatic modification (GO:0015015) 12 0 .00 - < 0.01 1.00E00 1.00E00 activation of meiosis involved in egg activation (GO:0060466) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast proliferation (GO:0007405) 57 0 .02 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process, chain elongation (GO:0015014) 8 0 .00 - < 0.01 1.00E00 1.00E00 pharynx development (GO:0060465) 3 0 .00 - < 0.01 1.00E00 1.00E00 glial cell fate determination (GO:0007403) 1 0 .00 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan biosynthetic process (GO:0015012) 29 0 .01 - < 0.01 1.00E00 1.00E00 lung lobe morphogenesis (GO:0060463) 7 0 .00 - < 0.01 1.00E00 1.00E00 lung lobe development (GO:0060462) 7 0 .00 - < 0.01 1.00E00 1.00E00 right lung morphogenesis (GO:0060461) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast fate determination (GO:0007400) 1 0 .00 - < 0.01 1.00E00 1.00E00 left lung morphogenesis (GO:0060460) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044) 48 0 .01 - < 0.01 1.00E00 1.00E00 phenol-containing compound biosynthetic process (GO:0046189) 35 0 .01 - < 0.01 1.00E00 1.00E00 aldehyde catabolic process (GO:0046185) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to intra-S DNA damage checkpoint signaling (GO:0072429) 4 0 .00 - < 0.01 1.00E00 1.00E00 aldehyde biosynthetic process (GO:0046184) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to DNA damage checkpoint signaling (GO:0072423) 7 0 .00 - < 0.01 1.00E00 1.00E00 left lung development (GO:0060459) 2 0 .00 - < 0.01 1.00E00 1.00E00 right lung development (GO:0060458) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of digestive system process (GO:0060457) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of digestive system process (GO:0060456) 15 0 .00 - < 0.01 1.00E00 1.00E00 somatic sex determination (GO:0018993) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gastric acid secretion (GO:0060455) 3 0 .00 - < 0.01 1.00E00 1.00E00 germ-line sex determination (GO:0018992) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gastric acid secretion (GO:0060453) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle contraction (GO:0060452) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hindgut contraction (GO:0060450) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of oxygen (GO:0003032) 5 0 .00 - < 0.01 1.00E00 1.00E00 polyol catabolic process (GO:0046174) 11 0 .00 - < 0.01 1.00E00 1.00E00 polyol biosynthetic process (GO:0046173) 48 0 .01 - < 0.01 1.00E00 1.00E00 response to mitotic cell cycle checkpoint signaling (GO:0072414) 1 0 .00 - < 0.01 1.00E00 1.00E00 bud elongation involved in lung branching (GO:0060449) 7 0 .00 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in lung branching (GO:0060448) 2 0 .00 - < 0.01 1.00E00 1.00E00 bud outgrowth involved in lung branching (GO:0060447) 3 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in salivary gland morphogenesis (GO:0060445) 16 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in mammary gland duct morphogenesis (GO:0060444) 22 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial large ribosomal subunit assembly (GO:1902775) 8 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland morphogenesis (GO:0060443) 45 0 .01 - < 0.01 1.00E00 1.00E00 late endosome to lysosome transport (GO:1902774) 20 0 .01 - < 0.01 1.00E00 1.00E00 branching involved in prostate gland morphogenesis (GO:0060442) 11 0 .00 - < 0.01 1.00E00 1.00E00 epithelial tube branching involved in lung morphogenesis (GO:0060441) 27 0 .01 - < 0.01 1.00E00 1.00E00 detection of hypoxic conditions in blood by carotid body chemoreceptor signaling (GO:0003029) 2 0 .00 - < 0.01 1.00E00 1.00E00 trachea formation (GO:0060440) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling (GO:0003027) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback (GO:0003026) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by baroreceptor feedback (GO:0003025) 5 0 .00 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate catabolic process (GO:0046168) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate biosynthetic process (GO:0046167) 4 0 .00 - < 0.01 1.00E00 1.00E00 glyceraldehyde-3-phosphate biosynthetic process (GO:0046166) 4 0 .00 - < 0.01 1.00E00 1.00E00 alcohol biosynthetic process (GO:0046165) 96 0 .03 - < 0.01 1.00E00 1.00E00 alcohol catabolic process (GO:0046164) 38 0 .01 - < 0.01 1.00E00 1.00E00 heme a metabolic process (GO:0046160) 10 0 .00 - < 0.01 1.00E00 1.00E00 activation of protein kinase A activity (GO:0034199) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to amino acid starvation (GO:0034198) 53 0 .02 - < 0.01 1.00E00 1.00E00 response to DNA integrity checkpoint signaling (GO:0072402) 7 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride transport (GO:0034197) 4 0 .00 - < 0.01 1.00E00 1.00E00 acylglycerol transport (GO:0034196) 4 0 .00 - < 0.01 1.00E00 1.00E00 trachea morphogenesis (GO:0060439) 11 0 .00 - < 0.01 1.00E00 1.00E00 trachea development (GO:0060438) 19 0 .01 - < 0.01 1.00E00 1.00E00 lung growth (GO:0060437) 5 0 .00 - < 0.01 1.00E00 1.00E00 bronchiole morphogenesis (GO:0060436) 1 0 .00 - < 0.01 1.00E00 1.00E00 isoprenoid biosynthetic process via mevalonate (GO:1902767) 2 0 .00 - < 0.01 1.00E00 1.00E00 bronchiole development (GO:0060435) 6 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell migration (GO:1902766) 2 0 .00 - < 0.01 1.00E00 1.00E00 bronchus morphogenesis (GO:0060434) 2 0 .00 - < 0.01 1.00E00 1.00E00 bronchus development (GO:0060433) 10 0 .00 - < 0.01 1.00E00 1.00E00 lung pattern specification process (GO:0060432) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary lung bud formation (GO:0060431) 1 0 .00 - < 0.01 1.00E00 1.00E00 lung saccule development (GO:0060430) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte development (GO:1902761) 2 0 .00 - < 0.01 1.00E00 1.00E00 vascular process in circulatory system (GO:0003018) 278 0 .08 - < 0.01 1.00E00 1.00E00 lymph circulation (GO:0003017) 2 0 .00 - < 0.01 1.00E00 1.00E00 respiratory system process (GO:0003016) 31 0 .01 - < 0.01 1.00E00 1.00E00 heart process (GO:0003015) 111 0 .03 - < 0.01 1.00E00 1.00E00 renal system process (GO:0003014) 130 0 .04 - < 0.01 1.00E00 1.00E00 circulatory system process (GO:0003013) 519 0 .15 - < 0.01 1.00E00 1.00E00 muscle system process (GO:0003012) 292 0 .09 - < 0.01 1.00E00 1.00E00 involuntary skeletal muscle contraction (GO:0003011) 3 0 .00 - < 0.01 1.00E00 1.00E00 voluntary skeletal muscle contraction (GO:0003010) 2 0 .00 - < 0.01 1.00E00 1.00E00 thiocyanate metabolic process (GO:0018969) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithelium development (GO:0060429) 1112 0 .32 - < 0.01 1.00E00 1.00E00 positive regulation of maintenance of mitotic sister chromatid cohesion (GO:0034184) 6 0 .00 - < 0.01 1.00E00 1.00E00 lung epithelium development (GO:0060428) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion (GO:0034183) 3 0 .00 - < 0.01 1.00E00 1.00E00 lung connective tissue development (GO:0060427) 2 0 .00 - < 0.01 1.00E00 1.00E00 propylene metabolic process (GO:0018964) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion (GO:0034182) 9 0 .00 - < 0.01 1.00E00 1.00E00 lung vasculature development (GO:0060426) 9 0 .00 - < 0.01 1.00E00 1.00E00 phthalate metabolic process (GO:0018963) 2 0 .00 - < 0.01 1.00E00 1.00E00 lung morphogenesis (GO:0060425) 49 0 .01 - < 0.01 1.00E00 1.00E00 4-nitrophenol metabolic process (GO:0018960) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear pore organization (GO:0006999) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heart growth (GO:0060421) 32 0 .01 - < 0.01 1.00E00 1.00E00 skeletal muscle contraction (GO:0003009) 31 0 .01 - < 0.01 1.00E00 1.00E00 nuclear envelope organization (GO:0006998) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of heart growth (GO:0060420) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle G2/M phase transition (GO:1902751) 31 0 .01 - < 0.01 1.00E00 1.00E00 system process (GO:0003008) 2128 0 .62 - < 0.01 1.00E00 1.00E00 nucleus organization (GO:0006997) 150 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle G2/M phase transition (GO:1902750) 72 0 .02 - < 0.01 1.00E00 1.00E00 heart morphogenesis (GO:0003007) 259 0 .08 - < 0.01 1.00E00 1.00E00 organelle organization (GO:0006996) 3060 1 .89 + 1.12 1.00E00 1.00E00 developmental process involved in reproduction (GO:0003006) 1029 1 .30 + 3.33 2.65E-01 1.00E00 cellular response to nitrogen starvation (GO:0006995) 12 0 .00 - < 0.01 1.00E00 1.00E00 regionalization (GO:0003002) 411 0 .12 - < 0.01 1.00E00 1.00E00 response to sterol depletion (GO:0006991) 12 0 .00 - < 0.01 1.00E00 1.00E00 pigment catabolic process (GO:0046149) 11 0 .00 - < 0.01 1.00E00 1.00E00 pigment biosynthetic process (GO:0046148) 41 0 .01 - < 0.01 1.00E00 1.00E00 tetrahydrobiopterin metabolic process (GO:0046146) 9 0 .00 - < 0.01 1.00E00 1.00E00 cyclodextrin metabolic process (GO:2000900) 1 0 .00 - < 0.01 1.00E00 1.00E00 phenol-containing compound metabolic process (GO:0018958) 92 0 .03 - < 0.01 1.00E00 1.00E00 heart growth (GO:0060419) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell cycle G2/M phase transition (GO:1902749) 119 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of lens fiber cell differentiation (GO:1902748) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to growth hormone (GO:0060416) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lens fiber cell differentiation (GO:1902747) 6 0 .00 - < 0.01 1.00E00 1.00E00 muscle tissue morphogenesis (GO:0060415) 70 0 .02 - < 0.01 1.00E00 1.00E00 regulation of lens fiber cell differentiation (GO:1902746) 9 0 .00 - < 0.01 1.00E00 1.00E00 imidazole-containing compound catabolic process (GO:0052805) 8 0 .00 - < 0.01 1.00E00 1.00E00 aorta smooth muscle tissue morphogenesis (GO:0060414) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lamellipodium organization (GO:1902745) 36 0 .01 - < 0.01 1.00E00 1.00E00 atrial septum morphogenesis (GO:0060413) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium organization (GO:1902744) 6 0 .00 - < 0.01 1.00E00 1.00E00 imidazole-containing compound metabolic process (GO:0052803) 13 0 .00 - < 0.01 1.00E00 1.00E00 ventricular septum morphogenesis (GO:0060412) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lamellipodium organization (GO:1902743) 50 0 .01 - < 0.01 1.00E00 1.00E00 cardiac septum morphogenesis (GO:0060411) 72 0 .02 - < 0.01 1.00E00 1.00E00 apoptotic process involved in development (GO:1902742) 33 0 .01 - < 0.01 1.00E00 1.00E00 response to unfolded protein (GO:0006986) 125 0 .04 - < 0.01 1.00E00 1.00E00 ER-nucleus signaling pathway (GO:0006984) 34 0 .01 - < 0.01 1.00E00 1.00E00 ER overload response (GO:0006983) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to lipid hydroperoxide (GO:0006982) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vitamin metabolic process (GO:0046137) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin metabolic process (GO:0046136) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside catabolic process (GO:0046135) 10 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside biosynthetic process (GO:0046134) 5 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside catabolic process (GO:0046133) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside metabolic process (GO:0046131) 8 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside catabolic process (GO:0046130) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 9 signaling pathway (GO:0034165) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 9 signaling pathway (GO:0034164) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 9 signaling pathway (GO:0034163) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of penile erection (GO:0060407) 1 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 9 signaling pathway (GO:0034162) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of penile erection (GO:0060406) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 8 signaling pathway (GO:0034161) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of penile erection (GO:0060405) 6 0 .00 - < 0.01 1.00E00 1.00E00 axonemal microtubule depolymerization (GO:0060404) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion transport into cytosol (GO:0060402) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to oxidative stress (GO:0006979) 369 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte proliferation (GO:1902732) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of growth hormone receptor signaling pathway (GO:0060400) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chondrocyte proliferation (GO:1902731) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proteoglycan biosynthetic process (GO:1902730) 5 0 .00 - < 0.01 1.00E00 1.00E00 DNA damage response (GO:0006974) 802 0 .23 - < 0.01 1.00E00 1.00E00 hyperosmotic response (GO:0006972) 23 0 .01 - < 0.01 1.00E00 1.00E00 hypotonic response (GO:0006971) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to osmotic stress (GO:0006970) 76 0 .02 - < 0.01 1.00E00 1.00E00 purine ribonucleoside biosynthetic process (GO:0046129) 11 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside metabolic process (GO:0046128) 22 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside catabolic process (GO:0046127) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside biosynthetic process (GO:0046126) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside metabolic process (GO:0046125) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside catabolic process (GO:0046124) 4 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside metabolic process (GO:0046122) 5 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside catabolic process (GO:0046121) 6 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside biosynthetic process (GO:0046120) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 8 signaling pathway (GO:0034159) 3 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 8 signaling pathway (GO:0034158) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 7 signaling pathway (GO:0034157) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 7 signaling pathway (GO:0034156) 1 0 .00 - < 0.01 1.00E00 1.00E00 nitroglycerin metabolic process (GO:0018937) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 7 signaling pathway (GO:0034155) 6 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 7 signaling pathway (GO:0034154) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of proteoglycan biosynthetic process (GO:1902729) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of growth factor dependent skeletal muscle satellite cell proliferation (GO:1902728) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 6 signaling pathway (GO:0034151) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle satellite cell differentiation (GO:1902726) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of satellite cell differentiation (GO:1902725) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle satellite cell proliferation (GO:1902724) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle satellite cell proliferation (GO:1902723) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of prolactin secretion (GO:1902722) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular defense response (GO:0006968) 51 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria (GO:0006965) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antibacterial peptide biosynthetic process (GO:0006963) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase catabolic process (GO:0046113) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase biosynthetic process (GO:0046112) 17 0 .00 - < 0.01 1.00E00 1.00E00 xanthine biosynthetic process (GO:0046111) 1 0 .00 - < 0.01 1.00E00 1.00E00 xanthine metabolic process (GO:0046110) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 5 signaling pathway (GO:0034148) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 5 signaling pathway (GO:0034147) 1 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 5 signaling pathway (GO:0034146) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 4 signaling pathway (GO:0034145) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 4 signaling pathway (GO:0034143) 29 0 .01 - < 0.01 1.00E00 1.00E00 multivesicular body sorting pathway (GO:0071985) 49 0 .01 - < 0.01 1.00E00 1.00E00 toll-like receptor 4 signaling pathway (GO:0034142) 32 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 3 signaling pathway (GO:0034141) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 3 signaling pathway (GO:0034140) 3 0 .00 - < 0.01 1.00E00 1.00E00 humoral immune response (GO:0006959) 274 0 .08 - < 0.01 1.00E00 1.00E00 complement activation, classical pathway (GO:0006958) 38 0 .01 - < 0.01 1.00E00 1.00E00 complement activation, alternative pathway (GO:0006957) 15 0 .00 - < 0.01 1.00E00 1.00E00 complement activation (GO:0006956) 56 0 .02 - < 0.01 1.00E00 1.00E00 immune response (GO:0006955) 1727 0 .50 - < 0.01 1.00E00 1.00E00 inflammatory response (GO:0006954) 583 0 .17 - < 0.01 1.00E00 1.00E00 acute-phase response (GO:0006953) 40 0 .01 - < 0.01 1.00E00 1.00E00 defense response (GO:0006952) 1490 0 .43 - < 0.01 1.00E00 1.00E00 response to stress (GO:0006950) 3513 0 1.02 - < 0.01 5.98E-01 1.00E00 uridine metabolic process (GO:0046108) 2 0 .00 - < 0.01 1.00E00 1.00E00 thymidine biosynthetic process (GO:0046105) 3 0 .00 - < 0.01 1.00E00 1.00E00 thymidine metabolic process (GO:0046104) 5 0 .00 - < 0.01 1.00E00 1.00E00 inosine biosynthetic process (GO:0046103) 3 0 .00 - < 0.01 1.00E00 1.00E00 inosine metabolic process (GO:0046102) 5 0 .00 - < 0.01 1.00E00 1.00E00 hypoxanthine biosynthetic process (GO:0046101) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of peptide antigen via MHC class I (GO:0002590) 2 0 .00 - < 0.01 1.00E00 1.00E00 hypoxanthine metabolic process (GO:0046100) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 3 signaling pathway (GO:0034139) 12 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 3 signaling pathway (GO:0034138) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor 2 signaling pathway (GO:0034137) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor 2 signaling pathway (GO:0034136) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor 2 signaling pathway (GO:0034135) 12 0 .00 - < 0.01 1.00E00 1.00E00 nitrobenzene metabolic process (GO:0018916) 4 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor 2 signaling pathway (GO:0034134) 6 0 .00 - < 0.01 1.00E00 1.00E00 cell gliding (GO:0071976) 1 0 .00 - < 0.01 1.00E00 1.00E00 extracellular exosome assembly (GO:0071971) 1 0 .00 - < 0.01 1.00E00 1.00E00 benzene metabolic process (GO:0018910) 1 0 .00 - < 0.01 1.00E00 1.00E00 syncytium formation (GO:0006949) 42 1 .01 + 81.67 1.22E-02 1.00E00 regulation of striated muscle contraction (GO:0006942) 96 0 .03 - < 0.01 1.00E00 1.00E00 striated muscle contraction (GO:0006941) 120 0 .03 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of peptide antigen via MHC class I (GO:0002589) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle contraction (GO:0006940) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002588) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002587) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of peptide antigen via MHC class II (GO:0002586) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide antigen (GO:0002585) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of peptide antigen (GO:0002584) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to ozone (GO:0010193) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of peptide antigen (GO:0002583) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002582) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002581) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002580) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034128) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of MyD88-independent toll-like receptor signaling pathway (GO:0034127) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034126) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034125) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of MyD88-dependent toll-like receptor signaling pathway (GO:0034124) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of toll-like receptor signaling pathway (GO:0034123) 4 0 .00 - < 0.01 1.00E00 1.00E00 multicellular organismal locomotion (GO:0071965) 2 0 .00 - < 0.01 1.00E00 1.00E00 ether metabolic process (GO:0018904) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of toll-like receptor signaling pathway (GO:0034122) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of toll-like receptor signaling pathway (GO:0034121) 37 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of cell polarity regulating cell shape (GO:0071963) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid cohesion, centromeric (GO:0071962) 3 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle contraction (GO:0006939) 59 0 .02 - < 0.01 1.00E00 1.00E00 regulation of muscle contraction (GO:0006937) 166 0 .05 - < 0.01 1.00E00 1.00E00 muscle contraction (GO:0006936) 236 0 .07 - < 0.01 1.00E00 1.00E00 chemotaxis (GO:0006935) 342 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion involved in substrate-bound cell migration (GO:0006933) 4 0 .00 - < 0.01 1.00E00 1.00E00 substrate-dependent cell migration, cell attachment to substrate (GO:0006931) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin E biosynthetic process (GO:0010189) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antigen processing and presentation (GO:0002579) 10 0 .00 - < 0.01 1.00E00 1.00E00 substrate-dependent cell migration, cell extension (GO:0006930) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation (GO:0002578) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation (GO:0002577) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cellular defense response (GO:0010186) 1 0 .00 - < 0.01 1.00E00 1.00E00 platelet degranulation (GO:0002576) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular defense response (GO:0010185) 1 0 .00 - < 0.01 1.00E00 1.00E00 basophil chemotaxis (GO:0002575) 1 0 .00 - < 0.01 1.00E00 1.00E00 thrombocyte differentiation (GO:0002574) 1 0 .00 - < 0.01 1.00E00 1.00E00 myeloid leukocyte differentiation (GO:0002573) 162 0 .05 - < 0.01 1.00E00 1.00E00 sugar mediated signaling pathway (GO:0010182) 7 0 .00 - < 0.01 1.00E00 1.00E00 pro-T cell differentiation (GO:0002572) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heterotypic cell-cell adhesion (GO:0034116) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heterotypic cell-cell adhesion (GO:0034115) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heterotypic cell-cell adhesion (GO:0034114) 23 0 .01 - < 0.01 1.00E00 1.00E00 heterotypic cell-cell adhesion (GO:0034113) 38 0 .01 - < 0.01 1.00E00 1.00E00 recycling endosome to Golgi transport (GO:0071955) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of homotypic cell-cell adhesion (GO:0034112) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of homotypic cell-cell adhesion (GO:0034111) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of homotypic cell-cell adhesion (GO:0034110) 39 0 .01 - < 0.01 1.00E00 1.00E00 conversion of methionyl-tRNA to N-formyl-methionyl-tRNA (GO:0071951) 1 0 .00 - < 0.01 1.00E00 1.00E00 substrate-dependent cell migration (GO:0006929) 23 0 .01 - < 0.01 1.00E00 1.00E00 inflammatory cell apoptotic process (GO:0006925) 7 0 .00 - < 0.01 1.00E00 1.00E00 activation-induced cell death of T cells (GO:0006924) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular component disassembly involved in execution phase of apoptosis (GO:0006921) 24 0 .01 - < 0.01 1.00E00 1.00E00 somatic diversification of T cell receptor genes (GO:0002568) 4 0 .00 - < 0.01 1.00E00 1.00E00 somatic diversification of immune receptors via somatic mutation (GO:0002566) 14 0 .00 - < 0.01 1.00E00 1.00E00 embryonic body morphogenesis (GO:0010172) 7 0 .00 - < 0.01 1.00E00 1.00E00 somatic diversification of immune receptors via germline recombination within a single locus (GO:0002562) 43 0 .01 - < 0.01 1.00E00 1.00E00 body morphogenesis (GO:0010171) 47 0 .01 - < 0.01 1.00E00 1.00E00 homotypic cell-cell adhesion (GO:0034109) 65 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of tissue remodeling (GO:0034105) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein deubiquitination involved in ubiquitin-dependent protein catabolic process (GO:0071947) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tissue remodeling (GO:0034104) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of tissue remodeling (GO:0034103) 77 0 .02 - < 0.01 1.00E00 1.00E00 erythrocyte homeostasis (GO:0034101) 116 0 .03 - < 0.01 1.00E00 1.00E00 nitrogen cycle metabolic process (GO:0071941) 15 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process (GO:0006915) 1056 0 .31 - < 0.01 1.00E00 1.00E00 autophagy (GO:0006914) 334 0 .10 - < 0.01 1.00E00 1.00E00 nucleocytoplasmic transport (GO:0006913) 249 0 .07 - < 0.01 1.00E00 1.00E00 phagocytosis, engulfment (GO:0006911) 33 0 .01 - < 0.01 1.00E00 1.00E00 phagocytosis, recognition (GO:0006910) 15 0 .00 - < 0.01 1.00E00 1.00E00 wax metabolic process (GO:0010166) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to X-ray (GO:0010165) 28 0 .01 - < 0.01 1.00E00 1.00E00 response to cesium ion (GO:0010164) 1 0 .00 - < 0.01 1.00E00 1.00E00 serotonin secretion by platelet (GO:0002554) 2 0 .00 - < 0.01 1.00E00 1.00E00 histamine secretion by mast cell (GO:0002553) 5 0 .00 - < 0.01 1.00E00 1.00E00 serotonin secretion by mast cell (GO:0002552) 1 0 .00 - < 0.01 1.00E00 1.00E00 mast cell chemotaxis (GO:0002551) 4 0 .00 - < 0.01 1.00E00 1.00E00 formation of animal organ boundary (GO:0010160) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin A import into cell (GO:0071939) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin A transport (GO:0071938) 1 0 .00 - < 0.01 1.00E00 1.00E00 thiamine transmembrane transport (GO:0071934) 7 0 .00 - < 0.01 1.00E00 1.00E00 replication fork reversal (GO:0071932) 4 0 .00 - < 0.01 1.00E00 1.00E00 phagocytosis (GO:0006909) 160 0 .05 - < 0.01 1.00E00 1.00E00 pinocytosis (GO:0006907) 11 0 .00 - < 0.01 1.00E00 1.00E00 vesicle fusion (GO:0006906) 101 0 .03 - < 0.01 1.00E00 1.00E00 vesicle docking involved in exocytosis (GO:0006904) 37 0 .01 - < 0.01 1.00E00 1.00E00 vesicle targeting (GO:0006903) 63 0 .02 - < 0.01 1.00E00 1.00E00 vesicle coating (GO:0006901) 36 0 .01 - < 0.01 1.00E00 1.00E00 specification of animal organ position (GO:0010159) 3 0 .00 - < 0.01 1.00E00 1.00E00 vesicle budding from membrane (GO:0006900) 82 0 .02 - < 0.01 1.00E00 1.00E00 monocyte chemotaxis (GO:0002548) 24 0 .01 - < 0.01 1.00E00 1.00E00 response to chlorate (GO:0010157) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proton transport (GO:0010155) 8 0 .00 - < 0.01 1.00E00 1.00E00 chronic inflammatory response (GO:0002544) 14 0 .00 - < 0.01 1.00E00 1.00E00 activation of blood coagulation via clotting cascade (GO:0002543) 2 0 .00 - < 0.01 1.00E00 1.00E00 Factor XII activation (GO:0002542) 2 0 .00 - < 0.01 1.00E00 1.00E00 activation of plasma proteins involved in acute inflammatory response (GO:0002541) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene production involved in inflammatory response (GO:0002540) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell differentiation (GO:0045687) 44 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell differentiation (GO:0045686) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glial cell differentiation (GO:0045685) 77 0 .02 - < 0.01 1.00E00 1.00E00 alpha-tubulin acetylation (GO:0071929) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epidermis development (GO:0045684) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of epidermis development (GO:0045683) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epidermis development (GO:0045682) 68 0 .02 - < 0.01 1.00E00 1.00E00 endocannabinoid signaling pathway (GO:0071926) 1 0 .00 - < 0.01 1.00E00 1.00E00 arachidonate metabolite production involved in inflammatory response (GO:0002538) 3 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide production involved in inflammatory response (GO:0002537) 1 0 .00 - < 0.01 1.00E00 1.00E00 respiratory burst involved in inflammatory response (GO:0002536) 2 0 .00 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate biosynthetic process, mevalonate pathway (GO:0010142) 2 0 .00 - < 0.01 1.00E00 1.00E00 production of molecular mediator involved in inflammatory response (GO:0002532) 19 0 .01 - < 0.01 1.00E00 1.00E00 G-quadruplex DNA formation (GO:0071919) 1 0 .00 - < 0.01 1.00E00 1.00E00 urea transmembrane transport (GO:0071918) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of osteoclast differentiation (GO:0045672) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of osteoclast differentiation (GO:0045671) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of osteoclast differentiation (GO:0045670) 74 0 .02 - < 0.01 1.00E00 1.00E00 synchronous neurotransmitter secretion (GO:0071911) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of liver left/right asymmetry (GO:0071910) 6 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide salvage (GO:0010138) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular permeability involved in acute inflammatory response (GO:0002528) 3 0 .00 - < 0.01 1.00E00 1.00E00 acute inflammatory response (GO:0002526) 73 0 .02 - < 0.01 1.00E00 1.00E00 hypersensitivity (GO:0002524) 12 0 .00 - < 0.01 1.00E00 1.00E00 proline catabolic process to glutamate (GO:0010133) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte migration involved in inflammatory response (GO:0002523) 21 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte migration involved in immune response (GO:0002522) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte differentiation (GO:0002521) 428 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of osteoblast differentiation (GO:0045669) 70 0 .02 - < 0.01 1.00E00 1.00E00 immune system development (GO:0002520) 171 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of osteoblast differentiation (GO:0045668) 50 0 .01 - < 0.01 1.00E00 1.00E00 regulation of osteoblast differentiation (GO:0045667) 131 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of neuron differentiation (GO:0045666) 92 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of neuron differentiation (GO:0045665) 73 0 .02 - < 0.01 1.00E00 1.00E00 determination of stomach left/right asymmetry (GO:0071909) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron differentiation (GO:0045664) 191 0 .06 - < 0.01 1.00E00 1.00E00 determination of intestine left/right asymmetry (GO:0071908) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myoblast differentiation (GO:0045663) 45 0 .01 - < 0.01 1.00E00 1.00E00 determination of digestive tract left/right asymmetry (GO:0071907) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myoblast differentiation (GO:0045662) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of myoblast differentiation (GO:0045661) 75 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil differentiation (GO:0045660) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein serine/threonine kinase activity (GO:0071902) 97 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein serine/threonine kinase activity (GO:0071901) 57 0 .02 - < 0.01 1.00E00 1.00E00 heterochromatin boundary formation (GO:0033696) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein serine/threonine kinase activity (GO:0071900) 185 0 .05 - < 0.01 1.00E00 1.00E00 neurofilament bundle assembly (GO:0033693) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of osteoblast proliferation (GO:0033690) 13 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell tolerance induction (GO:0002519) 3 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte chemotaxis across high endothelial venule (GO:0002518) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell tolerance induction (GO:0002517) 6 0 .00 - < 0.01 1.00E00 1.00E00 phenylacetate catabolic process (GO:0010124) 1 0 .00 - < 0.01 1.00E00 1.00E00 B cell tolerance induction (GO:0002514) 1 0 .00 - < 0.01 1.00E00 1.00E00 tolerance induction to self antigen (GO:0002513) 5 0 .00 - < 0.01 1.00E00 1.00E00 arginine catabolic process to proline via ornithine (GO:0010121) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil differentiation (GO:0045659) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil differentiation (GO:0045658) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte differentiation (GO:0045657) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte differentiation (GO:0045656) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of monocyte differentiation (GO:0045655) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of megakaryocyte differentiation (GO:0045654) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of megakaryocyte differentiation (GO:0045653) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of megakaryocyte differentiation (GO:0045652) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage differentiation (GO:0045651) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage differentiation (GO:0045650) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of osteoblast proliferation (GO:0033689) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of osteoblast proliferation (GO:0033688) 28 0 .01 - < 0.01 1.00E00 1.00E00 osteoblast proliferation (GO:0033687) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of luteinizing hormone secretion (GO:0033686) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of luteinizing hormone secretion (GO:0033685) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of luteinizing hormone secretion (GO:0033684) 7 0 .00 - < 0.01 1.00E00 1.00E00 central tolerance induction to self antigen (GO:0002509) 1 0 .00 - < 0.01 1.00E00 1.00E00 central tolerance induction (GO:0002508) 2 0 .00 - < 0.01 1.00E00 1.00E00 tolerance induction (GO:0002507) 19 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of polysaccharide antigen via MHC class II (GO:0002505) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II (GO:0002504) 34 0 .01 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC class II protein complex (GO:0002503) 16 0 .00 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC class I protein complex (GO:0002502) 6 0 .00 - < 0.01 1.00E00 1.00E00 peptide antigen assembly with MHC protein complex (GO:0002501) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macrophage differentiation (GO:0045649) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of erythrocyte differentiation (GO:0045648) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of L-dopa biosynthetic process (GO:1903197) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of erythrocyte differentiation (GO:0045647) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of erythrocyte differentiation (GO:0045646) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of L-dopa biosynthetic process (GO:1903195) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil differentiation (GO:0045645) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eosinophil differentiation (GO:0045643) 2 0 .00 - < 0.01 1.00E00 1.00E00 glyoxal catabolic process (GO:1903190) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of kinase activity (GO:0033674) 195 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of kinase activity (GO:0033673) 121 0 .04 - < 0.01 1.00E00 1.00E00 glyoxal metabolic process (GO:1903189) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid oxidation (GO:0019395) 82 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid cell differentiation (GO:0045639) 105 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid cell differentiation (GO:0045638) 85 0 .02 - < 0.01 1.00E00 1.00E00 regulation of myeloid cell differentiation (GO:0045637) 203 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of melanocyte differentiation (GO:0045636) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of melanocyte differentiation (GO:0045634) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mechanoreceptor differentiation (GO:0045633) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mechanoreceptor differentiation (GO:0045632) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine biosynthetic process (GO:1903181) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mechanoreceptor differentiation (GO:0045631) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopamine biosynthetic process (GO:1903180) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 2 cell differentiation (GO:0045630) 7 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar cortex maturation (GO:0021699) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar cortex structural organization (GO:0021698) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar cortex formation (GO:0021697) 27 0 .01 - < 0.01 1.00E00 1.00E00 cerebellar cortex morphogenesis (GO:0021696) 38 0 .01 - < 0.01 1.00E00 1.00E00 cerebellar cortex development (GO:0021695) 53 0 .02 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer formation (GO:0021694) 15 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer structural organization (GO:0021693) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer morphogenesis (GO:0021692) 19 0 .01 - < 0.01 1.00E00 1.00E00 galactose catabolic process (GO:0019388) 9 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer maturation (GO:0021691) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dopamine biosynthetic process (GO:1903179) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 2 cell differentiation (GO:0045629) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 2 cell differentiation (GO:0045628) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 1 cell differentiation (GO:0045627) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 1 cell differentiation (GO:0045626) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 1 cell differentiation (GO:0045625) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper cell differentiation (GO:0045624) 25 0 .01 - < 0.01 1.00E00 1.00E00 fatty alcohol metabolic process (GO:1903173) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper cell differentiation (GO:0045623) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of T-helper cell differentiation (GO:0045622) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte differentiation (GO:0045621) 136 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion transmembrane transport (GO:1903170) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte differentiation (GO:0045620) 62 0 .02 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer formation (GO:0021688) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer morphogenesis (GO:0021687) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granular layer maturation (GO:0021686) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granular layer structural organization (GO:0021685) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granular layer formation (GO:0021684) 8 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granular layer morphogenesis (GO:0021683) 10 0 .00 - < 0.01 1.00E00 1.00E00 nerve maturation (GO:0021682) 4 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granular layer development (GO:0021681) 14 0 .00 - < 0.01 1.00E00 1.00E00 glycolipid catabolic process (GO:0019377) 21 0 .01 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell layer development (GO:0021680) 28 0 .01 - < 0.01 1.00E00 1.00E00 galactolipid catabolic process (GO:0019376) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion transmembrane transport (GO:1903169) 166 0 .05 - < 0.01 1.00E00 1.00E00 galactolipid biosynthetic process (GO:0019375) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte differentiation (GO:0045619) 222 0 .06 - < 0.01 1.00E00 1.00E00 galactolipid metabolic process (GO:0019374) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of keratinocyte differentiation (GO:0045618) 20 0 .01 - < 0.01 1.00E00 1.00E00 epoxygenase P450 pathway (GO:0019373) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte differentiation (GO:0045617) 9 0 .00 - < 0.01 1.00E00 1.00E00 lipoxygenase pathway (GO:0019372) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of keratinocyte differentiation (GO:0045616) 40 0 .01 - < 0.01 1.00E00 1.00E00 response to polycyclic arene (GO:1903165) 3 0 .00 - < 0.01 1.00E00 1.00E00 cyclooxygenase pathway (GO:0019371) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene biosynthetic process (GO:0019370) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of hemocyte differentiation (GO:0045611) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hemocyte differentiation (GO:0045610) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar molecular layer development (GO:0021679) 2 0 .00 - < 0.01 1.00E00 1.00E00 third ventricle development (GO:0021678) 4 0 .00 - < 0.01 1.00E00 1.00E00 nerve development (GO:0021675) 100 0 .03 - < 0.01 1.00E00 1.00E00 lysobisphosphatidic acid metabolic process (GO:2001311) 2 0 .00 - < 0.01 1.00E00 1.00E00 arachidonate metabolic process (GO:0019369) 54 0 .02 - < 0.01 1.00E00 1.00E00 fatty acid elongation, unsaturated fatty acid (GO:0019368) 7 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid elongation, saturated fatty acid (GO:0019367) 8 0 .00 - < 0.01 1.00E00 1.00E00 lateral ventricle development (GO:0021670) 12 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleotide salvage (GO:0019365) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inner ear auditory receptor cell differentiation (GO:0045609) 2 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleotide catabolic process (GO:0019364) 52 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of inner ear auditory receptor cell differentiation (GO:0045608) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleotide biosynthetic process (GO:0019363) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of inner ear auditory receptor cell differentiation (GO:0045607) 10 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleotide metabolic process (GO:0019362) 128 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of epidermal cell differentiation (GO:0045606) 29 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of epidermal cell differentiation (GO:0045605) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epidermal cell differentiation (GO:0045604) 61 0 .02 - < 0.01 1.00E00 1.00E00 nervous system development (GO:0007399) 2265 0 .66 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell differentiation (GO:0045603) 11 0 .00 - < 0.01 1.00E00 1.00E00 ectoderm development (GO:0007398) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell differentiation (GO:0045602) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell differentiation (GO:0045601) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of fat cell differentiation (GO:0045600) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cell-cell adhesion mediated by integrin (GO:0033634) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell-cell adhesion mediated by integrin (GO:0033633) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell-cell adhesion mediated by integrin (GO:0033632) 11 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell adhesion mediated by integrin (GO:0033631) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell adhesion mediated by integrin (GO:0033630) 22 0 .01 - < 0.01 1.00E00 1.00E00 lipoxin B4 biosynthetic process (GO:2001306) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoxin B4 metabolic process (GO:2001304) 2 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 5 formation (GO:0021666) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoxin A4 biosynthetic process (GO:2001303) 3 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 5 structural organization (GO:0021665) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoxin A4 metabolic process (GO:2001302) 5 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 5 morphogenesis (GO:0021664) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoxin biosynthetic process (GO:2001301) 4 0 .00 - < 0.01 1.00E00 1.00E00 lipoxin metabolic process (GO:2001300) 6 0 .00 - < 0.01 1.00E00 1.00E00 nicotinamide nucleotide biosynthetic process (GO:0019359) 27 0 .01 - < 0.01 1.00E00 1.00E00 rhombomere 3 formation (GO:0021660) 1 0 .00 - < 0.01 1.00E00 1.00E00 cGAS/STING signaling pathway (GO:0140896) 5 0 .00 - < 0.01 1.00E00 1.00E00 cell surface toll-like receptor signaling pathway (GO:0140895) 36 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of autophagy of mitochondrion (GO:1903147) 12 0 .00 - < 0.01 1.00E00 1.00E00 endolysosomal toll-like receptor signaling pathway (GO:0140894) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of autophagy of mitochondrion (GO:1903146) 53 0 .02 - < 0.01 1.00E00 1.00E00 pattern specification process (GO:0007389) 460 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of endothelial barrier (GO:1903142) 6 0 .00 - < 0.01 1.00E00 1.00E00 posterior compartment specification (GO:0007388) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of endothelial barrier (GO:1903141) 2 0 .00 - < 0.01 1.00E00 1.00E00 anterior compartment pattern formation (GO:0007387) 1 0 .00 - < 0.01 1.00E00 1.00E00 dolichol phosphate mannose biosynthetic process (GO:0180047) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of endothelial barrier (GO:1903140) 17 0 .00 - < 0.01 1.00E00 1.00E00 compartment pattern specification (GO:0007386) 5 0 .00 - < 0.01 1.00E00 1.00E00 GPI anchored protein biosynthesis (GO:0180046) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion mediated by integrin (GO:0033629) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion mediated by integrin (GO:0033628) 49 0 .01 - < 0.01 1.00E00 1.00E00 cell adhesion mediated by integrin (GO:0033627) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of integrin activation by cell surface receptor linked signal transduction (GO:0033626) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of integrin activation (GO:0033625) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of integrin activation (GO:0033624) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of integrin activation (GO:0033623) 17 0 .00 - < 0.01 1.00E00 1.00E00 integrin activation (GO:0033622) 10 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 3 structural organization (GO:0021659) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 3 morphogenesis (GO:0021658) 2 0 .00 - < 0.01 1.00E00 1.00E00 dolichol metabolic process (GO:0019348) 8 0 .00 - < 0.01 1.00E00 1.00E00 DNA replication-dependent chromatin disassembly (GO:0140889) 3 0 .00 - < 0.01 1.00E00 1.00E00 vestibulocochlear nerve formation (GO:0021650) 5 0 .00 - < 0.01 1.00E00 1.00E00 interferon-mediated signaling pathway (GO:0140888) 64 0 .02 - < 0.01 1.00E00 1.00E00 transsulfuration (GO:0019346) 4 0 .00 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process (GO:0019344) 3 0 .00 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process via cystathionine (GO:0019343) 2 0 .00 - < 0.01 1.00E00 1.00E00 dibenzo-p-dioxin catabolic process (GO:0019341) 1 0 .00 - < 0.01 1.00E00 1.00E00 zinc export across plasma membrane (GO:0140882) 4 0 .00 - < 0.01 1.00E00 1.00E00 segment specification (GO:0007379) 17 0 .00 - < 0.01 1.00E00 1.00E00 mononuclear cell differentiation (GO:1903131) 362 0 .11 - < 0.01 1.00E00 1.00E00 membrane protein proteolysis (GO:0033619) 39 0 .01 - < 0.01 1.00E00 1.00E00 lncRNA processing (GO:0180035) 3 0 .00 - < 0.01 1.00E00 1.00E00 co-transcriptional lncRNA 3' end processing, cleavage and polyadenylation pathway (GO:0180034) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial cytochrome c oxidase assembly (GO:0033617) 27 0 .01 - < 0.01 1.00E00 1.00E00 ventral midline determination (GO:0007371) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial proton-transporting ATP synthase complex assembly (GO:0033615) 8 0 .00 - < 0.01 1.00E00 1.00E00 vestibulocochlear nerve structural organization (GO:0021649) 2 0 .00 - < 0.01 1.00E00 1.00E00 vestibulocochlear nerve morphogenesis (GO:0021648) 7 0 .00 - < 0.01 1.00E00 1.00E00 vestibulocochlear nerve maturation (GO:0021647) 1 0 .00 - < 0.01 1.00E00 1.00E00 vagus nerve morphogenesis (GO:0021644) 2 0 .00 - < 0.01 1.00E00 1.00E00 trochlear nerve formation (GO:0021642) 1 0 .00 - < 0.01 1.00E00 1.00E00 phenol-containing compound catabolic process (GO:0019336) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to cell cycle checkpoint signaling (GO:0072396) 7 0 .00 - < 0.01 1.00E00 1.00E00 microtubule anchoring at microtubule organizing center (GO:0072393) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of centriole-centriole cohesion (GO:1903126) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation (GO:1903125) 1 0 .00 - < 0.01 1.00E00 1.00E00 gastrulation (GO:0007369) 171 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of TRAIL-activated apoptotic signaling pathway (GO:1903122) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of left/right symmetry (GO:0007368) 134 0 .04 - < 0.01 1.00E00 1.00E00 regulation of TRAIL-activated apoptotic signaling pathway (GO:1903121) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial small ribosomal subunit assembly (GO:0180026) 3 0 .00 - < 0.01 1.00E00 1.00E00 oxalate metabolic process (GO:0033609) 1 0 .00 - < 0.01 1.00E00 1.00E00 cytosolic small ribosomal subunit assembly (GO:0180025) 3 0 .00 - < 0.01 1.00E00 1.00E00 chemokine receptor transport within lipid bilayer (GO:0033606) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of catecholamine secretion (GO:0033605) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of catecholamine secretion (GO:0033604) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine secretion (GO:0033603) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopamine secretion (GO:0033602) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mammary gland epithelial cell proliferation (GO:0033601) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mammary gland epithelial cell proliferation (GO:0033600) 4 0 .00 - < 0.01 1.00E00 1.00E00 trochlear nerve morphogenesis (GO:0021639) 1 0 .00 - < 0.01 1.00E00 1.00E00 trigeminal nerve structural organization (GO:0021637) 6 0 .00 - < 0.01 1.00E00 1.00E00 trigeminal nerve morphogenesis (GO:0021636) 6 0 .00 - < 0.01 1.00E00 1.00E00 optic nerve structural organization (GO:0021633) 2 0 .00 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide catabolic process (GO:0072389) 1 0 .00 - < 0.01 1.00E00 1.00E00 optic nerve morphogenesis (GO:0021631) 6 0 .00 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide biosynthetic process (GO:0072388) 3 0 .00 - < 0.01 1.00E00 1.00E00 olfactory nerve maturation (GO:0021630) 2 0 .00 - < 0.01 1.00E00 1.00E00 flavin adenine dinucleotide metabolic process (GO:0072387) 4 0 .00 - < 0.01 1.00E00 1.00E00 plus-end-directed organelle transport along microtubule (GO:0072386) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to actin cytoskeleton (GO:1903119) 5 0 .00 - < 0.01 1.00E00 1.00E00 minus-end-directed organelle transport along microtubule (GO:0072385) 4 0 .00 - < 0.01 1.00E00 1.00E00 organelle transport along microtubule (GO:0072384) 86 0 .03 - < 0.01 1.00E00 1.00E00 interleukin-22-mediated signaling pathway (GO:0140865) 2 0 .00 - < 0.01 1.00E00 1.00E00 pentose catabolic process (GO:0019323) 4 0 .00 - < 0.01 1.00E00 1.00E00 plus-end-directed vesicle transport along microtubule (GO:0072383) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament-based movement (GO:1903116) 3 0 .00 - < 0.01 1.00E00 1.00E00 pentose biosynthetic process (GO:0019322) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin filament-based movement (GO:1903115) 41 0 .01 - < 0.01 1.00E00 1.00E00 pentose metabolic process (GO:0019321) 13 0 .00 - < 0.01 1.00E00 1.00E00 hexose catabolic process (GO:0019320) 49 1 .01 + 70.00 1.42E-02 1.00E00 DNA repair-dependent chromatin remodeling (GO:0140861) 23 0 .01 - < 0.01 1.00E00 1.00E00 thorax and anterior abdomen determination (GO:0007356) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside import across plasma membrane (GO:0180015) 1 0 .00 - < 0.01 1.00E00 1.00E00 zygotic determination of anterior/posterior axis, embryo (GO:0007354) 6 0 .00 - < 0.01 1.00E00 1.00E00 zygotic specification of dorsal/ventral axis (GO:0007352) 3 0 .00 - < 0.01 1.00E00 1.00E00 co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway (GO:0180012) 11 0 .00 - < 0.01 1.00E00 1.00E00 tripartite regional subdivision (GO:0007351) 20 0 .01 - < 0.01 1.00E00 1.00E00 cytosolic mRNA polyadenylation (GO:0180011) 3 0 .00 - < 0.01 1.00E00 1.00E00 blastoderm segmentation (GO:0007350) 25 0 .01 - < 0.01 1.00E00 1.00E00 co-transcriptional mRNA 3'-end processing, cleavage and polyadenylation pathway (GO:0180010) 9 0 .00 - < 0.01 1.00E00 1.00E00 olfactory nerve formation (GO:0021628) 2 0 .00 - < 0.01 1.00E00 1.00E00 olfactory nerve morphogenesis (GO:0021627) 2 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system maturation (GO:0021626) 7 0 .00 - < 0.01 1.00E00 1.00E00 oculomotor nerve formation (GO:0021623) 2 0 .00 - < 0.01 1.00E00 1.00E00 hexose biosynthetic process (GO:0019319) 49 0 .01 - < 0.01 1.00E00 1.00E00 oculomotor nerve morphogenesis (GO:0021622) 2 0 .00 - < 0.01 1.00E00 1.00E00 hexose metabolic process (GO:0019318) 163 1 .05 + 21.04 4.66E-02 1.00E00 blood coagulation, fibrin clot formation (GO:0072378) 16 0 .00 - < 0.01 1.00E00 1.00E00 amylopectin metabolic process (GO:2000896) 1 0 .00 - < 0.01 1.00E00 1.00E00 fucose catabolic process (GO:0019317) 10 1 .00 + > 100 2.91E-03 1.00E00 blood coagulation, common pathway (GO:0072377) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein activation cascade (GO:0072376) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial transcription (GO:1903109) 3 0 .00 - < 0.01 1.00E00 1.00E00 medium-term memory (GO:0072375) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial transcription (GO:1903108) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellobiose catabolic process (GO:2000892) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellobiose metabolic process (GO:2000891) 1 0 .00 - < 0.01 1.00E00 1.00E00 inositol catabolic process (GO:0019310) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellularization (GO:0007349) 2 0 .00 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process (GO:1903100) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle (GO:0007346) 491 0 .14 - < 0.01 1.00E00 1.00E00 pronuclear fusion (GO:0007344) 1 0 .00 - < 0.01 1.00E00 1.00E00 egg activation (GO:0007343) 11 0 .00 - < 0.01 1.00E00 1.00E00 fusion of sperm to egg plasma membrane involved in single fertilization (GO:0007342) 28 0 .01 - < 0.01 1.00E00 1.00E00 penetration of zona pellucida (GO:0007341) 9 0 .00 - < 0.01 1.00E00 1.00E00 acrosome reaction (GO:0007340) 24 0 .01 - < 0.01 1.00E00 1.00E00 hypoglossal nerve morphogenesis (GO:0021618) 1 0 .00 - < 0.01 1.00E00 1.00E00 glossopharyngeal nerve morphogenesis (GO:0021615) 4 0 .00 - < 0.01 1.00E00 1.00E00 mannose catabolic process (GO:0019309) 1 0 .00 - < 0.01 1.00E00 1.00E00 facial nerve structural organization (GO:0021612) 9 0 .00 - < 0.01 1.00E00 1.00E00 facial nerve morphogenesis (GO:0021610) 11 0 .00 - < 0.01 1.00E00 1.00E00 D-ribose catabolic process (GO:0019303) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dipeptide transport (GO:2000880) 2 0 .00 - < 0.01 1.00E00 1.00E00 binding of sperm to zona pellucida (GO:0007339) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of growth hormone receptor signaling pathway (GO:0060399) 3 0 .00 - < 0.01 1.00E00 1.00E00 single fertilization (GO:0007338) 171 0 .05 - < 0.01 1.00E00 1.00E00 regulation of growth hormone receptor signaling pathway (GO:0060398) 8 0 .00 - < 0.01 1.00E00 1.00E00 growth hormone receptor signaling pathway via JAK-STAT (GO:0060397) 11 0 .00 - < 0.01 1.00E00 1.00E00 growth hormone receptor signaling pathway (GO:0060396) 22 0 .01 - < 0.01 1.00E00 1.00E00 SMAD protein signal transduction (GO:0060395) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of SMAD protein signal transduction (GO:0060392) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of SMAD protein signal transduction (GO:0060391) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of SMAD protein signal transduction (GO:0060390) 67 0 .02 - < 0.01 1.00E00 1.00E00 cranial nerve maturation (GO:0021605) 3 0 .00 - < 0.01 1.00E00 1.00E00 cranial nerve structural organization (GO:0021604) 11 0 .00 - < 0.01 1.00E00 1.00E00 cranial nerve formation (GO:0021603) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oligopeptide transport (GO:2000878) 2 0 .00 - < 0.01 1.00E00 1.00E00 cranial nerve morphogenesis (GO:0021602) 31 0 .01 - < 0.01 1.00E00 1.00E00 circulatory system development (GO:0072359) 940 0 .27 - < 0.01 1.00E00 1.00E00 chromosome passenger complex localization to kinetochore (GO:0072356) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of progesterone secretion (GO:2000872) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of progesterone secretion (GO:2000870) 2 0 .00 - < 0.01 1.00E00 1.00E00 tricarboxylic acid metabolic process (GO:0072350) 15 0 .00 - < 0.01 1.00E00 1.00E00 synapse assembly involved in innervation (GO:0060386) 2 0 .00 - < 0.01 1.00E00 1.00E00 axonogenesis involved in innervation (GO:0060385) 9 0 .00 - < 0.01 1.00E00 1.00E00 innervation (GO:0060384) 29 0 .01 - < 0.01 1.00E00 1.00E00 peptide pheromone maturation (GO:0007323) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA strand elongation (GO:0060383) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA strand elongation (GO:0060382) 17 0 .00 - < 0.01 1.00E00 1.00E00 sperm displacement (GO:0007321) 1 0 .00 - < 0.01 1.00E00 1.00E00 insemination (GO:0007320) 12 0 .00 - < 0.01 1.00E00 1.00E00 sulfur compound transport (GO:0072348) 65 0 .02 - < 0.01 1.00E00 1.00E00 response to anesthetic (GO:0072347) 4 0 .00 - < 0.01 1.00E00 1.00E00 rescue of stalled ribosome (GO:0072344) 34 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone secretion (GO:2000860) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactam catabolic process (GO:0072340) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell myoblast differentiation (GO:0060379) 11 0 .00 - < 0.01 1.00E00 1.00E00 cytosol to Golgi apparatus transport (GO:0140820) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of brood size (GO:0060378) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell differentiation (GO:0060377) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell differentiation (GO:0060376) 1 0 .00 - < 0.01 1.00E00 1.00E00 pole plasm assembly (GO:0007315) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell differentiation (GO:0060375) 3 0 .00 - < 0.01 1.00E00 1.00E00 oocyte anterior/posterior axis specification (GO:0007314) 6 0 .00 - < 0.01 1.00E00 1.00E00 mast cell differentiation (GO:0060374) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell membrane depolarization (GO:0060373) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of atrial cardiac muscle cell membrane repolarization (GO:0060372) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) 9 0 .00 - < 0.01 1.00E00 1.00E00 susceptibility to T cell mediated cytotoxicity (GO:0060370) 2 0 .00 - < 0.01 1.00E00 1.00E00 guanine biosynthetic process (GO:0046099) 1 0 .00 - < 0.01 1.00E00 1.00E00 guanine metabolic process (GO:0046098) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of aldosterone secretion (GO:2000859) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aldosterone secretion (GO:2000858) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mineralocorticoid secretion (GO:2000857) 3 0 .00 - < 0.01 1.00E00 1.00E00 deoxyinosine metabolic process (GO:0046094) 2 0 .00 - < 0.01 1.00E00 1.00E00 lactam metabolic process (GO:0072338) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mineralocorticoid secretion (GO:2000856) 1 0 .00 - < 0.01 1.00E00 1.00E00 modified amino acid transport (GO:0072337) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mineralocorticoid secretion (GO:2000855) 7 0 .00 - < 0.01 1.00E00 1.00E00 deoxycytidine metabolic process (GO:0046092) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of corticosterone secretion (GO:2000854) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of corticosterone secretion (GO:2000853) 1 0 .00 - < 0.01 1.00E00 1.00E00 deoxyadenosine metabolic process (GO:0046090) 3 0 .00 - < 0.01 1.00E00 1.00E00 UDP-galactose transmembrane transport (GO:0072334) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of corticosterone secretion (GO:2000852) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid secretion (GO:2000851) 5 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway by p53 class mediator (GO:0072332) 58 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid secretion (GO:2000850) 4 0 .00 - < 0.01 1.00E00 1.00E00 signal transduction by p53 class mediator (GO:0072331) 93 0 .03 - < 0.01 1.00E00 1.00E00 monocarboxylic acid biosynthetic process (GO:0072330) 171 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060369) 5 0 .00 - < 0.01 1.00E00 1.00E00 oocyte axis specification (GO:0007309) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Fc receptor mediated stimulatory signaling pathway (GO:0060368) 10 0 .00 - < 0.01 1.00E00 1.00E00 oocyte construction (GO:0007308) 8 0 .00 - < 0.01 1.00E00 1.00E00 sagittal suture morphogenesis (GO:0060367) 1 0 .00 - < 0.01 1.00E00 1.00E00 lambdoid suture morphogenesis (GO:0060366) 1 0 .00 - < 0.01 1.00E00 1.00E00 frontal suture morphogenesis (GO:0060364) 4 0 .00 - < 0.01 1.00E00 1.00E00 cranial suture morphogenesis (GO:0060363) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuroblast proliferation (GO:1902692) 44 0 .01 - < 0.01 1.00E00 1.00E00 respiratory basal cell differentiation (GO:1902691) 2 0 .00 - < 0.01 1.00E00 1.00E00 cytidine metabolic process (GO:0046087) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid secretion (GO:2000849) 11 0 .00 - < 0.01 1.00E00 1.00E00 adenosine biosynthetic process (GO:0046086) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of corticosteroid hormone secretion (GO:2000848) 8 0 .00 - < 0.01 1.00E00 1.00E00 adenosine metabolic process (GO:0046085) 11 0 .00 - < 0.01 1.00E00 1.00E00 monocarboxylic acid catabolic process (GO:0072329) 110 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of corticosteroid hormone secretion (GO:2000847) 5 0 .00 - < 0.01 1.00E00 1.00E00 adenine biosynthetic process (GO:0046084) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of corticosteroid hormone secretion (GO:2000846) 18 0 .01 - < 0.01 1.00E00 1.00E00 adenine metabolic process (GO:0046083) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of testosterone secretion (GO:2000845) 3 0 .00 - < 0.01 1.00E00 1.00E00 dUTP catabolic process (GO:0046081) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of testosterone secretion (GO:2000843) 3 0 .00 - < 0.01 1.00E00 1.00E00 dUTP metabolic process (GO:0046080) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to ammonium ion (GO:0060359) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NAD metabolic process (GO:1902688) 2 0 .00 - < 0.01 1.00E00 1.00E00 dibenzo-p-dioxin metabolic process (GO:0018894) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell adhesion molecule production (GO:0060355) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion molecule production (GO:0060354) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor localization to synapse (GO:1902685) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion molecule production (GO:0060353) 8 0 .00 - < 0.01 1.00E00 1.00E00 cell adhesion molecule production (GO:0060352) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor localization to synapse (GO:1902683) 29 0 .01 - < 0.01 1.00E00 1.00E00 cartilage development involved in endochondral bone morphogenesis (GO:0060351) 32 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to pericentric heterochromatin (GO:1902682) 1 0 .00 - < 0.01 1.00E00 1.00E00 endochondral bone morphogenesis (GO:0060350) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of RNA biosynthetic process (GO:1902680) 1669 0 .49 - < 0.01 1.00E00 1.00E00 dUMP catabolic process (GO:0046079) 6 0 .00 - < 0.01 1.00E00 1.00E00 dUMP metabolic process (GO:0046078) 8 0 .00 - < 0.01 1.00E00 1.00E00 dUDP metabolic process (GO:0046077) 2 0 .00 - < 0.01 1.00E00 1.00E00 dTTP metabolic process (GO:0046075) 4 0 .00 - < 0.01 1.00E00 1.00E00 vesicle uncoating (GO:0072319) 6 0 .00 - < 0.01 1.00E00 1.00E00 dTMP catabolic process (GO:0046074) 3 0 .00 - < 0.01 1.00E00 1.00E00 clathrin coat disassembly (GO:0072318) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of androgen secretion (GO:2000836) 1 0 .00 - < 0.01 1.00E00 1.00E00 dTMP metabolic process (GO:0046073) 7 0 .00 - < 0.01 1.00E00 1.00E00 dTDP metabolic process (GO:0046072) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of androgen secretion (GO:2000834) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of steroid hormone secretion (GO:2000833) 12 1 .00 + > 100 3.49E-03 1.00E00 dGTP metabolic process (GO:0046070) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of steroid hormone secretion (GO:2000832) 5 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerular epithelial cell development (GO:0072313) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of steroid hormone secretion (GO:2000831) 24 1 .01 + > 100 6.98E-03 1.00E00 metanephric glomerular epithelial cell differentiation (GO:0072312) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of parathyroid hormone secretion (GO:2000830) 1 0 .00 - < 0.01 1.00E00 1.00E00 glomerular epithelial cell differentiation (GO:0072311) 24 0 .01 - < 0.01 1.00E00 1.00E00 glomerular epithelial cell development (GO:0072310) 12 0 .00 - < 0.01 1.00E00 1.00E00 bone morphogenesis (GO:0060349) 100 0 .03 - < 0.01 1.00E00 1.00E00 bone development (GO:0060348) 199 1 .06 + 17.24 5.66E-02 1.00E00 negative regulation of RNA biosynthetic process (GO:1902679) 1287 0 .38 - < 0.01 1.00E00 1.00E00 heart trabecula formation (GO:0060347) 15 0 .00 - < 0.01 1.00E00 1.00E00 carbon tetrachloride metabolic process (GO:0018885) 1 0 .00 - < 0.01 1.00E00 1.00E00 bone trabecula formation (GO:0060346) 9 0 .00 - < 0.01 1.00E00 1.00E00 spleen trabecula formation (GO:0060345) 1 0 .00 - < 0.01 1.00E00 1.00E00 trabecula formation (GO:0060343) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cellular localization (GO:0060341) 1006 0 .29 - < 0.01 1.00E00 1.00E00 positive regulation of type I interferon-mediated signaling pathway (GO:0060340) 20 0 .01 - < 0.01 1.00E00 1.00E00 cGMP catabolic process (GO:0046069) 5 0 .00 - < 0.01 1.00E00 1.00E00 cGMP metabolic process (GO:0046068) 18 0 .01 - < 0.01 1.00E00 1.00E00 dGDP catabolic process (GO:0046067) 1 0 .00 - < 0.01 1.00E00 1.00E00 dGDP metabolic process (GO:0046066) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of parathyroid hormone secretion (GO:2000828) 1 0 .00 - < 0.01 1.00E00 1.00E00 dCTP metabolic process (GO:0046065) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA surveillance (GO:2000827) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072308) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heart morphogenesis (GO:2000826) 9 0 .00 - < 0.01 1.00E00 1.00E00 dCMP metabolic process (GO:0046063) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of androgen receptor activity (GO:2000825) 1 0 .00 - < 0.01 1.00E00 1.00E00 dATP catabolic process (GO:0046061) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis (GO:0072305) 2 0 .00 - < 0.01 1.00E00 1.00E00 dATP metabolic process (GO:0046060) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis (GO:0072304) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of behavioral fear response (GO:2000822) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glomerular metanephric mesangial cell proliferation (GO:0072303) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of grooming behavior (GO:2000821) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric glomerular mesangial cell proliferation (GO:0072302) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to cytokine (GO:0034097) 868 0 .25 - < 0.01 1.00E00 1.00E00 regulation of metanephric glomerular mesangial cell proliferation (GO:0072301) 2 0 .00 - < 0.01 1.00E00 1.00E00 biphenyl metabolic process (GO:0018879) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric glomerulus development (GO:0072300) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type I interferon-mediated signaling pathway (GO:0060339) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of type I interferon-mediated signaling pathway (GO:0060338) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of axon guidance (GO:1902669) 3 0 .00 - < 0.01 1.00E00 1.00E00 type I interferon-mediated signaling pathway (GO:0060337) 48 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of axon guidance (GO:1902668) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of maintenance of sister chromatid cohesion (GO:0034093) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type II interferon-mediated signaling pathway (GO:0060336) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of axon guidance (GO:1902667) 12 0 .00 - < 0.01 1.00E00 1.00E00 benzoate metabolic process (GO:0018874) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of sister chromatid cohesion (GO:0034092) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type II interferon-mediated signaling pathway (GO:0060335) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of maintenance of sister chromatid cohesion (GO:0034091) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type II interferon-mediated signaling pathway (GO:0060334) 15 0 .00 - < 0.01 1.00E00 1.00E00 arsonoacetate metabolic process (GO:0018872) 2 0 .00 - < 0.01 1.00E00 1.00E00 type II interferon-mediated signaling pathway (GO:0060333) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of response to type II interferon (GO:0060332) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to type II interferon (GO:0060331) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to type II interferon (GO:0060330) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucose mediated signaling pathway (GO:1902661) 3 0 .00 - < 0.01 1.00E00 1.00E00 dAMP catabolic process (GO:0046059) 4 0 .00 - < 0.01 1.00E00 1.00E00 cAMP metabolic process (GO:0046058) 23 0 .01 - < 0.01 1.00E00 1.00E00 dADP catabolic process (GO:0046057) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleotide-excision repair (GO:2000819) 28 0 .01 - < 0.01 1.00E00 1.00E00 dADP metabolic process (GO:0046056) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myoblast proliferation (GO:2000818) 2 0 .00 - < 0.01 1.00E00 1.00E00 dGMP catabolic process (GO:0046055) 4 0 .00 - < 0.01 1.00E00 1.00E00 dGMP metabolic process (GO:0046054) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic sister chromatid separation (GO:2000816) 33 0 .01 - < 0.01 1.00E00 1.00E00 dAMP metabolic process (GO:0046053) 7 0 .00 - < 0.01 1.00E00 1.00E00 UTP catabolic process (GO:0046052) 1 0 .00 - < 0.01 1.00E00 1.00E00 UTP metabolic process (GO:0046051) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of barbed-end actin filament capping (GO:2000813) 4 0 .00 - < 0.01 1.00E00 1.00E00 UMP catabolic process (GO:0046050) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of barbed-end actin filament capping (GO:2000812) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of anoikis (GO:2000811) 19 0 .01 - < 0.01 1.00E00 1.00E00 establishment of meiotic sister chromatid cohesion (GO:0034089) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bicellular tight junction assembly (GO:2000810) 23 0 .01 - < 0.01 1.00E00 1.00E00 maintenance of mitotic sister chromatid cohesion (GO:0034088) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of mitotic sister chromatid cohesion (GO:0034087) 7 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of sister chromatid cohesion (GO:0034086) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of sister chromatid cohesion (GO:0034085) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucose mediated signaling pathway (GO:1902659) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasmic actin-based contraction involved in cell motility (GO:0060327) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell chemotaxis (GO:0060326) 213 0 .06 - < 0.01 1.00E00 1.00E00 face morphogenesis (GO:0060325) 32 0 .01 - < 0.01 1.00E00 1.00E00 calcium ion import into cytosol (GO:1902656) 29 0 .01 - < 0.01 1.00E00 1.00E00 face development (GO:0060324) 53 0 .02 - < 0.01 1.00E00 1.00E00 CENP-A containing chromatin assembly (GO:0034080) 10 0 .00 - < 0.01 1.00E00 1.00E00 head morphogenesis (GO:0060323) 39 0 .01 - < 0.01 1.00E00 1.00E00 head development (GO:0060322) 797 0 .23 - < 0.01 1.00E00 1.00E00 secondary alcohol biosynthetic process (GO:1902653) 37 0 .01 - < 0.01 1.00E00 1.00E00 secondary alcohol metabolic process (GO:1902652) 132 0 .04 - < 0.01 1.00E00 1.00E00 receptor-mediated endocytosis (GO:0006898) 168 0 .05 - < 0.01 1.00E00 1.00E00 endocytosis (GO:0006897) 504 0 .15 - < 0.01 1.00E00 1.00E00 Golgi to vacuole transport (GO:0006896) 19 0 .01 - < 0.01 1.00E00 1.00E00 Golgi to endosome transport (GO:0006895) 17 0 .00 - < 0.01 1.00E00 1.00E00 Golgi to plasma membrane transport (GO:0006893) 56 0 .02 - < 0.01 1.00E00 1.00E00 post-Golgi vesicle-mediated transport (GO:0006892) 101 0 .03 - < 0.01 1.00E00 1.00E00 intra-Golgi vesicle-mediated transport (GO:0006891) 35 0 .01 - < 0.01 1.00E00 1.00E00 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum (GO:0006890) 50 0 .01 - < 0.01 1.00E00 1.00E00 UMP metabolic process (GO:0046049) 15 0 .00 - < 0.01 1.00E00 1.00E00 UDP metabolic process (GO:0046048) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle clustering (GO:2000809) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle clustering (GO:2000808) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle clustering (GO:2000807) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000806) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000805) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase II transcription, poly(A)-coupled (GO:2000804) 3 0 .00 - < 0.01 1.00E00 1.00E00 ITP metabolic process (GO:0046041) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation (GO:2000802) 1 0 .00 - < 0.01 1.00E00 1.00E00 IMP metabolic process (GO:0046040) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endocardial cushion to mesenchymal transition involved in heart valve formation (GO:2000800) 1 0 .00 - < 0.01 1.00E00 1.00E00 primitive erythrocyte differentiation (GO:0060319) 4 0 .00 - < 0.01 1.00E00 1.00E00 definitive erythrocyte differentiation (GO:0060318) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac epithelial to mesenchymal transition (GO:0060317) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314) 17 0 .00 - < 0.01 1.00E00 1.00E00 tertiary alcohol biosynthetic process (GO:1902645) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel remodeling (GO:0060313) 2 0 .00 - < 0.01 1.00E00 1.00E00 tertiary alcohol metabolic process (GO:1902644) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood vessel remodeling (GO:0060312) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of elastin catabolic process (GO:0060311) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of elastin catabolic process (GO:0060310) 1 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum to Golgi vesicle-mediated transport (GO:0006888) 123 0 .04 - < 0.01 1.00E00 1.00E00 exocytosis (GO:0006887) 240 0 .07 - < 0.01 1.00E00 1.00E00 intracellular protein transport (GO:0006886) 559 0 .16 - < 0.01 1.00E00 1.00E00 regulation of pH (GO:0006885) 106 0 .03 - < 0.01 1.00E00 1.00E00 cell volume homeostasis (GO:0006884) 35 0 .01 - < 0.01 1.00E00 1.00E00 intracellular sodium ion homeostasis (GO:0006883) 22 0 .01 - < 0.01 1.00E00 1.00E00 intracellular zinc ion homeostasis (GO:0006882) 36 0 .01 - < 0.01 1.00E00 1.00E00 GTP metabolic process (GO:0046039) 26 0 .01 - < 0.01 1.00E00 1.00E00 GMP catabolic process (GO:0046038) 3 0 .00 - < 0.01 1.00E00 1.00E00 GMP metabolic process (GO:0046037) 27 0 .01 - < 0.01 1.00E00 1.00E00 CTP metabolic process (GO:0046036) 16 0 .00 - < 0.01 1.00E00 1.00E00 CMP metabolic process (GO:0046035) 8 0 .00 - < 0.01 1.00E00 1.00E00 ATP metabolic process (GO:0046034) 167 0 .05 - < 0.01 1.00E00 1.00E00 AMP metabolic process (GO:0046033) 24 0 .01 - < 0.01 1.00E00 1.00E00 ADP catabolic process (GO:0046032) 50 0 .01 - < 0.01 1.00E00 1.00E00 ADP metabolic process (GO:0046031) 57 0 .02 - < 0.01 1.00E00 1.00E00 protein localization to Golgi apparatus (GO:0034067) 34 0 .01 - < 0.01 1.00E00 1.00E00 mRNA methylguanosine-cap decapping (GO:0110156) 14 0 .00 - < 0.01 1.00E00 1.00E00 elastin catabolic process (GO:0060309) 3 0 .00 - < 0.01 1.00E00 1.00E00 NAD-cap decapping (GO:0110155) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA decapping (GO:0110154) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) 23 0 .01 - < 0.01 1.00E00 1.00E00 stress granule assembly (GO:0034063) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization (GO:0060306) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell diameter (GO:0060305) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol dephosphorylation (GO:0060304) 5 0 .00 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process (GO:1902635) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytokine activity (GO:0060302) 2 0 .00 - < 0.01 1.00E00 1.00E00 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process (GO:1902633) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of membrane hyperpolarization (GO:1902632) 2 0 .00 - < 0.01 1.00E00 1.00E00 intracellular iron ion homeostasis (GO:0006879) 74 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cytokine activity (GO:0060300) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane hyperpolarization (GO:1902631) 2 0 .00 - < 0.01 1.00E00 1.00E00 intracellular copper ion homeostasis (GO:0006878) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane hyperpolarization (GO:1902630) 5 0 .00 - < 0.01 1.00E00 1.00E00 intracellular calcium ion homeostasis (GO:0006874) 202 0 .06 - < 0.01 1.00E00 1.00E00 intracellular monoatomic ion homeostasis (GO:0006873) 441 0 .13 - < 0.01 1.00E00 1.00E00 response to anoxia (GO:0034059) 2 0 .00 - < 0.01 1.00E00 1.00E00 endosomal vesicle fusion (GO:0034058) 14 0 .00 - < 0.01 1.00E00 1.00E00 DNA biosynthetic process (GO:0071897) 99 0 .03 - < 0.01 1.00E00 1.00E00 protein localization to adherens junction (GO:0071896) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability involved in cellular response to UV (GO:1902629) 1 0 .00 - < 0.01 1.00E00 1.00E00 odontoblast differentiation (GO:0071895) 8 0 .00 - < 0.01 1.00E00 1.00E00 assembly of large subunit precursor of preribosome (GO:1902626) 1 0 .00 - < 0.01 1.00E00 1.00E00 symbiont-induced defense-related programmed cell death (GO:0034050) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil migration (GO:1902624) 36 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil migration (GO:1902623) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil migration (GO:1902622) 47 0 .01 - < 0.01 1.00E00 1.00E00 lipid transport (GO:0006869) 356 0 .10 - < 0.01 1.00E00 1.00E00 glutamine transport (GO:0006868) 9 0 .00 - < 0.01 1.00E00 1.00E00 asparagine transport (GO:0006867) 4 0 .00 - < 0.01 1.00E00 1.00E00 amino acid transport (GO:0006865) 138 0 .04 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide transport (GO:0006864) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase transport (GO:0006863) 12 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide transport (GO:0006862) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by glucose (GO:0046016) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription by glucose (GO:0046015) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell homeostatic proliferation (GO:0046013) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of circadian sleep/wake cycle, non-REM sleep (GO:0046010) 2 0 .00 - < 0.01 1.00E00 1.00E00 macrophage apoptotic process (GO:0071888) 3 0 .00 - < 0.01 1.00E00 1.00E00 Norrin signaling pathway (GO:0110135) 4 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte apoptotic process (GO:0071887) 48 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to fluoride (GO:1902618) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to fluoride (GO:1902617) 4 0 .00 - < 0.01 1.00E00 1.00E00 O-acyl-L-carnitine transmembrane transport (GO:1902616) 2 0 .00 - < 0.01 1.00E00 1.00E00 immune response involved in response to exogenous dsRNA (GO:1902615) 1 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating adrenergic receptor signaling pathway (GO:0071882) 2 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071881) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of anti-Mullerian hormone signaling pathway (GO:1902613) 1 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071880) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anti-Mullerian hormone signaling pathway (GO:1902612) 1 0 .00 - < 0.01 1.00E00 1.00E00 extracellular transport (GO:0006858) 51 0 .01 - < 0.01 1.00E00 1.00E00 oligopeptide transport (GO:0006857) 17 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic transmembrane transport (GO:0006855) 17 0 .00 - < 0.01 1.00E00 1.00E00 carnitine shuttle (GO:0006853) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial calcium ion transmembrane transport (GO:0006851) 21 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial pyruvate transmembrane transport (GO:0006850) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of activated T cell proliferation (GO:0046007) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of activated T cell proliferation (GO:0046006) 41 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of peptide antigen via MHC class II (GO:0002495) 33 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of circadian sleep/wake cycle, REM sleep (GO:0046005) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class II (GO:0002491) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071879) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside bisphosphate biosynthetic process (GO:0034036) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adenylate cyclase-activating adrenergic receptor signaling pathway (GO:0071878) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside bisphosphate metabolic process (GO:0034035) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-inhibiting adrenergic receptor signaling pathway (GO:0071877) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of large conductance calcium-activated potassium channel activity (GO:1902608) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside bisphosphate biosynthetic process (GO:0034033) 2 0 .00 - < 0.01 1.00E00 1.00E00 adrenergic receptor signaling pathway (GO:0071875) 23 0 .01 - < 0.01 1.00E00 1.00E00 purine nucleoside bisphosphate metabolic process (GO:0034032) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to norepinephrine stimulus (GO:0071874) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to norepinephrine (GO:0071873) 2 0 .00 - < 0.01 1.00E00 1.00E00 heterotrimeric G-protein complex assembly (GO:1902605) 1 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside bisphosphate biosynthetic process (GO:0034030) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to epinephrine stimulus (GO:0071872) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to epinephrine (GO:0071871) 15 0 .00 - < 0.01 1.00E00 1.00E00 carnitine transmembrane transport (GO:1902603) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to catecholamine stimulus (GO:0071870) 51 0 .01 - < 0.01 1.00E00 1.00E00 silver ion transmembrane transport (GO:1902601) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate transport (GO:0006848) 8 0 .00 - < 0.01 1.00E00 1.00E00 proton transmembrane transport (GO:1902600) 183 0 .05 - < 0.01 1.00E00 1.00E00 acetate transport (GO:0006846) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial citrate transmembrane transport (GO:0006843) 1 0 .00 - < 0.01 1.00E00 1.00E00 tricarboxylic acid transport (GO:0006842) 5 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent (GO:0002489) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway (GO:0002488) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent (GO:0002486) 14 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent (GO:0002485) 2 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway (GO:0002484) 15 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen (GO:0002483) 23 0 .01 - < 0.01 1.00E00 1.00E00 specification of animal organ identity (GO:0010092) 18 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent (GO:0002481) 2 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (GO:0002480) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to catecholamine (GO:0071869) 54 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to monoamine stimulus (GO:0071868) 51 0 .01 - < 0.01 1.00E00 1.00E00 response to monoamine (GO:0071867) 54 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of lipid transporter activity (GO:0110114) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process in bone marrow cell (GO:0071866) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid transporter activity (GO:0110113) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process in bone marrow cell (GO:0071865) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation in bone marrow (GO:0071864) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of animal organ morphogenesis (GO:0110111) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to silicon dioxide (GO:0034021) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation in bone marrow (GO:0071863) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of animal organ morphogenesis (GO:0110110) 36 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial transport (GO:0006839) 179 0 .05 - < 0.01 1.00E00 1.00E00 serotonin transport (GO:0006837) 12 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter transport (GO:0006836) 142 0 .04 - < 0.01 1.00E00 1.00E00 dicarboxylic acid transport (GO:0006835) 83 0 .02 - < 0.01 1.00E00 1.00E00 water transport (GO:0006833) 28 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:0002479) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen (GO:0002478) 41 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class Ib (GO:0002477) 4 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class Ib (GO:0002476) 15 0 .00 - < 0.01 1.00E00 1.00E00 polarity specification of proximal/distal axis (GO:0010085) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation via MHC class Ib (GO:0002475) 23 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) 35 0 .01 - < 0.01 1.00E00 1.00E00 plasmacytoid dendritic cell antigen processing and presentation (GO:0002470) 1 0 .00 - < 0.01 1.00E00 1.00E00 mRNA alternative polyadenylation (GO:0110104) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to triglyceride (GO:0034014) 3 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion transport (GO:0006829) 32 0 .01 - < 0.01 1.00E00 1.00E00 manganese ion transport (GO:0006828) 12 0 .00 - < 0.01 1.00E00 1.00E00 iron ion transport (GO:0006826) 52 0 .02 - < 0.01 1.00E00 1.00E00 copper ion transport (GO:0006825) 16 0 .00 - < 0.01 1.00E00 1.00E00 cobalt ion transport (GO:0006824) 8 0 .00 - < 0.01 1.00E00 1.00E00 chloride transport (GO:0006821) 124 0 .04 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell antigen processing and presentation (GO:0002469) 3 0 .00 - < 0.01 1.00E00 1.00E00 monoatomic anion transport (GO:0006820) 163 0 .05 - < 0.01 1.00E00 1.00E00 dendritic cell antigen processing and presentation (GO:0002468) 5 0 .00 - < 0.01 1.00E00 1.00E00 germinal center formation (GO:0002467) 10 0 .00 - < 0.01 1.00E00 1.00E00 peripheral tolerance induction (GO:0002465) 2 0 .00 - < 0.01 1.00E00 1.00E00 tolerance induction dependent upon immune response (GO:0002461) 3 0 .00 - < 0.01 1.00E00 1.00E00 zygote asymmetric cell division (GO:0010070) 1 0 .00 - < 0.01 1.00E00 1.00E00 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002460) 267 0 .08 - < 0.01 1.00E00 1.00E00 actin filament debranching (GO:0071846) 2 0 .00 - < 0.01 1.00E00 1.00E00 corpus callosum development (GO:0022038) 27 0 .01 - < 0.01 1.00E00 1.00E00 cellular component organization or biogenesis (GO:0071840) 6083 1 1.77 - .56 6.77E-01 1.00E00 metencephalon development (GO:0022037) 117 0 .03 - < 0.01 1.00E00 1.00E00 phosphate ion transport (GO:0006817) 19 0 .01 - < 0.01 1.00E00 1.00E00 calcium ion transport (GO:0006816) 270 0 .08 - < 0.01 1.00E00 1.00E00 sodium ion transport (GO:0006814) 197 0 .06 - < 0.01 1.00E00 1.00E00 potassium ion transport (GO:0006813) 185 0 .05 - < 0.01 1.00E00 1.00E00 monoatomic cation transport (GO:0006812) 831 0 .24 - < 0.01 1.00E00 1.00E00 telencephalon glial cell migration (GO:0022030) 28 0 .01 - < 0.01 1.00E00 1.00E00 monoatomic ion transport (GO:0006811) 1024 0 .30 - < 0.01 1.00E00 1.00E00 transport (GO:0006810) 3703 0 1.08 - < 0.01 6.00E-01 1.00E00 peripheral T cell tolerance induction (GO:0002458) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell antigen processing and presentation (GO:0002457) 5 0 .00 - < 0.01 1.00E00 1.00E00 T cell mediated immunity (GO:0002456) 40 0 .01 - < 0.01 1.00E00 1.00E00 humoral immune response mediated by circulating immunoglobulin (GO:0002455) 43 0 .01 - < 0.01 1.00E00 1.00E00 peripheral B cell tolerance induction (GO:0002451) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fat cell differentiation (GO:0045599) 53 0 .02 - < 0.01 1.00E00 1.00E00 B cell antigen processing and presentation (GO:0002450) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fat cell differentiation (GO:0045598) 133 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of cell differentiation (GO:0045597) 865 0 .25 - < 0.01 1.00E00 1.00E00 negative regulation of cell differentiation (GO:0045596) 668 0 .19 - < 0.01 1.00E00 1.00E00 regulation of cell differentiation (GO:0045595) 1553 0 .45 - < 0.01 1.00E00 1.00E00 apoptotic process in bone marrow cell (GO:0071839) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation in bone marrow (GO:0071838) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of regulatory T cell differentiation (GO:0045591) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of regulatory T cell differentiation (GO:0045590) 5 0 .00 - < 0.01 1.00E00 1.00E00 telencephalon cell migration (GO:0022029) 62 0 .02 - < 0.01 1.00E00 1.00E00 intermediate-density lipoprotein particle clearance (GO:0071831) 1 0 .00 - < 0.01 1.00E00 1.00E00 tangential migration from the subventricular zone to the olfactory bulb (GO:0022028) 6 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride-rich lipoprotein particle clearance (GO:0071830) 6 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide biosynthetic process (GO:0006809) 22 0 .01 - < 0.01 1.00E00 1.00E00 interkinetic nuclear migration (GO:0022027) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitrogen utilization (GO:0006808) 3 0 .00 - < 0.01 1.00E00 1.00E00 N(omega),N(omega)-dimethyl-L-arginine catabolic process (GO:2001299) 1 0 .00 - < 0.01 1.00E00 1.00E00 N(omega),N(omega)-dimethyl-L-arginine metabolic process (GO:2001298) 1 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic metabolic process (GO:0006805) 132 0 .04 - < 0.01 1.00E00 1.00E00 malonyl-CoA biosynthetic process (GO:2001295) 2 0 .00 - < 0.01 1.00E00 1.00E00 malonyl-CoA catabolic process (GO:2001294) 4 0 .00 - < 0.01 1.00E00 1.00E00 superoxide metabolic process (GO:0006801) 47 0 .01 - < 0.01 1.00E00 1.00E00 malonyl-CoA metabolic process (GO:2001293) 6 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte mediated immunity (GO:0002449) 262 0 .08 - < 0.01 1.00E00 1.00E00 mast cell mediated immunity (GO:0002448) 33 0 .01 - < 0.01 1.00E00 1.00E00 eosinophil mediated immunity (GO:0002447) 6 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil mediated immunity (GO:0002446) 27 0 .01 - < 0.01 1.00E00 1.00E00 type II hypersensitivity (GO:0002445) 9 0 .00 - < 0.01 1.00E00 1.00E00 myeloid leukocyte mediated immunity (GO:0002444) 71 0 .02 - < 0.01 1.00E00 1.00E00 leukocyte mediated immunity (GO:0002443) 319 0 .09 - < 0.01 1.00E00 1.00E00 serotonin secretion involved in inflammatory response (GO:0002442) 3 0 .00 - < 0.01 1.00E00 1.00E00 histamine secretion involved in inflammatory response (GO:0002441) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of regulatory T cell differentiation (GO:0045589) 36 0 .01 - < 0.01 1.00E00 1.00E00 production of molecular mediator of immune response (GO:0002440) 50 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of gamma-delta T cell differentiation (GO:0045588) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gamma-delta T cell differentiation (GO:0045586) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytotoxic T cell differentiation (GO:0045585) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytotoxic T cell differentiation (GO:0045584) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytotoxic T cell differentiation (GO:0045583) 3 0 .00 - < 0.01 1.00E00 1.00E00 plasma lipoprotein particle organization (GO:0071827) 51 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell differentiation (GO:0045582) 121 0 .04 - < 0.01 1.00E00 1.00E00 protein-RNA complex organization (GO:0071826) 205 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of T cell differentiation (GO:0045581) 52 0 .02 - < 0.01 1.00E00 1.00E00 protein-lipid complex organization (GO:0071825) 54 0 .02 - < 0.01 1.00E00 1.00E00 regulation of T cell differentiation (GO:0045580) 190 0 .06 - < 0.01 1.00E00 1.00E00 protein-DNA complex organization (GO:0071824) 222 0 .06 - < 0.01 1.00E00 1.00E00 lateral ganglionic eminence cell proliferation (GO:0022018) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of caveolin-mediated endocytosis (GO:2001288) 3 0 .00 - < 0.01 1.00E00 1.00E00 pallium cell proliferation in forebrain (GO:0022013) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of caveolin-mediated endocytosis (GO:2001287) 2 0 .00 - < 0.01 1.00E00 1.00E00 subpallium cell proliferation in forebrain (GO:0022012) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of caveolin-mediated endocytosis (GO:2001286) 6 0 .00 - < 0.01 1.00E00 1.00E00 myelination in peripheral nervous system (GO:0022011) 30 0 .01 - < 0.01 1.00E00 1.00E00 central nervous system myelination (GO:0022010) 27 0 .01 - < 0.01 1.00E00 1.00E00 chronic inflammatory response to antigenic stimulus (GO:0002439) 2 0 .00 - < 0.01 1.00E00 1.00E00 acute inflammatory response to antigenic stimulus (GO:0002438) 18 0 .01 - < 0.01 1.00E00 1.00E00 inflammatory response to antigenic stimulus (GO:0002437) 38 0 .01 - < 0.01 1.00E00 1.00E00 response to mycotoxin (GO:0010046) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of unsaturated fatty acid biosynthetic process (GO:2001280) 8 0 .00 - < 0.01 1.00E00 1.00E00 immune complex clearance by monocytes and macrophages (GO:0002436) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to nickel cation (GO:0010045) 1 0 .00 - < 0.01 1.00E00 1.00E00 immune complex clearance by erythrocytes (GO:0002435) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to aluminum ion (GO:0010044) 4 0 .00 - < 0.01 1.00E00 1.00E00 immune complex clearance (GO:0002434) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to zinc ion (GO:0010043) 54 0 .02 - < 0.01 1.00E00 1.00E00 immune response-regulating cell surface receptor signaling pathway involved in phagocytosis (GO:0002433) 23 0 .01 - < 0.01 1.00E00 1.00E00 response to manganese ion (GO:0010042) 17 0 .00 - < 0.01 1.00E00 1.00E00 granuloma formation (GO:0002432) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to iron(III) ion (GO:0010041) 4 0 .00 - < 0.01 1.00E00 1.00E00 Fc receptor mediated stimulatory signaling pathway (GO:0002431) 25 0 .01 - < 0.01 1.00E00 1.00E00 response to iron(II) ion (GO:0010040) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell differentiation (GO:0045579) 17 0 .00 - < 0.01 1.00E00 1.00E00 complement receptor mediated signaling pathway (GO:0002430) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of B cell differentiation (GO:0045578) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell differentiation (GO:0045577) 35 0 .01 - < 0.01 1.00E00 1.00E00 mast cell activation (GO:0045576) 34 0 .01 - < 0.01 1.00E00 1.00E00 basophil activation (GO:0045575) 3 0 .00 - < 0.01 1.00E00 1.00E00 tail-anchored membrane protein insertion into ER membrane (GO:0071816) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fever generation by positive regulation of prostaglandin secretion (GO:0071812) 2 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system vasculogenesis (GO:0022009) 5 0 .00 - < 0.01 1.00E00 1.00E00 neurogenesis (GO:0022008) 1397 0 .41 - < 0.01 1.00E00 1.00E00 convergent extension involved in neural plate elongation (GO:0022007) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of unsaturated fatty acid biosynthetic process (GO:2001279) 11 0 .00 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary maturation during brain development (GO:0022004) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to iron ion (GO:0010039) 29 0 .01 - < 0.01 1.00E00 1.00E00 immune response-activating cell surface receptor signaling pathway (GO:0002429) 250 0 .07 - < 0.01 1.00E00 1.00E00 response to metal ion (GO:0010038) 346 1 .10 + 9.91 9.67E-02 1.00E00 antigen processing and presentation of peptide antigen via MHC class Ib (GO:0002428) 16 0 .00 - < 0.01 1.00E00 1.00E00 response to carbon dioxide (GO:0010037) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to acetate (GO:0010034) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell mediated immune response to tumor cell (GO:0002424) 3 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell mediated immune response to tumor cell (GO:0002423) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic chromosome condensation (GO:0010032) 6 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002420) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein transmembrane transport (GO:0071806) 74 0 .02 - < 0.01 1.00E00 1.00E00 potassium ion transmembrane transport (GO:0071805) 168 0 .05 - < 0.01 1.00E00 1.00E00 regulation of mammary gland epithelial cell proliferation (GO:0033599) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of podosome assembly (GO:0071803) 10 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland epithelial cell proliferation (GO:0033598) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of podosome assembly (GO:0071801) 13 0 .00 - < 0.01 1.00E00 1.00E00 podosome assembly (GO:0071800) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to genistein (GO:0033595) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to hydroxyisoflavone (GO:0033594) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to L-ascorbic acid (GO:0033591) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to cobalamin (GO:0033590) 4 0 .00 - < 0.01 1.00E00 1.00E00 T cell mediated cytotoxicity directed against tumor cell target (GO:0002419) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of semaphorin-plexin signaling pathway (GO:2001262) 1 0 .00 - < 0.01 1.00E00 1.00E00 immune response to tumor cell (GO:0002418) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of semaphorin-plexin signaling pathway (GO:2001260) 3 0 .00 - < 0.01 1.00E00 1.00E00 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor (GO:0002416) 1 0 .00 - < 0.01 1.00E00 1.00E00 wax biosynthetic process (GO:0010025) 4 0 .00 - < 0.01 1.00E00 1.00E00 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor (GO:0002415) 2 0 .00 - < 0.01 1.00E00 1.00E00 immunoglobulin transcytosis in epithelial cells (GO:0002414) 4 0 .00 - < 0.01 1.00E00 1.00E00 antigen transcytosis by M cells in mucosal-associated lymphoid tissue (GO:0002412) 1 0 .00 - < 0.01 1.00E00 1.00E00 amylopectin biosynthetic process (GO:0010021) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cation channel activity (GO:2001259) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cation channel activity (GO:2001258) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cation channel activity (GO:2001257) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of store-operated calcium entry (GO:2001256) 14 0 .00 - < 0.01 1.00E00 1.00E00 RNA glycosylation (GO:0141217) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chromosome organization (GO:2001252) 104 0 .03 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell chemotaxis (GO:0002408) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipase C/protein kinase C signal transduction (GO:0141214) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chromosome organization (GO:2001251) 78 0 .02 - < 0.01 1.00E00 1.00E00 dendritic cell chemotaxis (GO:0002407) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ammonia assimilation cycle (GO:2001250) 1 0 .00 - < 0.01 1.00E00 1.00E00 antigen sampling by M cells in mucosal-associated lymphoid tissue (GO:0002406) 1 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C/protein kinase C signal transduction (GO:0141212) 5 0 .00 - < 0.01 1.00E00 1.00E00 antigen sampling in mucosal-associated lymphoid tissue (GO:0002404) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to meiotic spindle midzone (GO:1903096) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein K48-linked deubiquitination (GO:1903094) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein K48-linked deubiquitination (GO:1903093) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cholesterol biosynthetic process (GO:0045542) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol biosynthetic process (GO:0045541) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholesterol biosynthetic process (GO:0045540) 26 0 .01 - < 0.01 1.00E00 1.00E00 response to testosterone (GO:0033574) 44 0 .01 - < 0.01 1.00E00 1.00E00 transferrin transport (GO:0033572) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ammonia assimilation cycle (GO:2001248) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylcholine biosynthetic process (GO:2001247) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylcholine biosynthetic process (GO:2001246) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylcholine biosynthetic process (GO:2001245) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway (GO:2001244) 60 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway (GO:2001243) 104 0 .03 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway (GO:2001242) 176 0 .05 - < 0.01 1.00E00 1.00E00 dipeptide transmembrane transport from lysosomal lumen to cytosol (GO:0141204) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001240) 35 0 .01 - < 0.01 1.00E00 1.00E00 pyroptotic cell death (GO:0141201) 5 0 .00 - < 0.01 1.00E00 1.00E00 cardioblast differentiation (GO:0010002) 14 0 .00 - < 0.01 1.00E00 1.00E00 glial cell differentiation (GO:0010001) 218 0 .06 - < 0.01 1.00E00 1.00E00 tyrosine biosynthetic process, by oxidation of phenylalanine (GO:0019293) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to condensed chromosome (GO:1903083) 13 0 .00 - < 0.01 1.00E00 1.00E00 siderophore biosynthetic process (GO:0019290) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of C-C chemokine receptor CCR7 signaling pathway (GO:1903082) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of C-C chemokine receptor CCR7 signaling pathway (GO:1903080) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA replication, Okazaki fragment processing (GO:0033567) 2 0 .00 - < 0.01 1.00E00 1.00E00 gamma-tubulin complex localization (GO:0033566) 3 0 .00 - < 0.01 1.00E00 1.00E00 anterior/posterior axon guidance (GO:0033564) 7 0 .00 - < 0.01 1.00E00 1.00E00 dorsal/ventral axon guidance (GO:0033563) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001239) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of extrinsic apoptotic signaling pathway (GO:2001238) 59 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of extrinsic apoptotic signaling pathway (GO:2001237) 97 0 .03 - < 0.01 1.00E00 1.00E00 regulation of extrinsic apoptotic signaling pathway (GO:2001236) 161 0 .05 - < 0.01 1.00E00 1.00E00 abducens nerve formation (GO:0021599) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic signaling pathway (GO:2001235) 143 0 .04 - < 0.01 1.00E00 1.00E00 abducens nerve morphogenesis (GO:0021598) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic signaling pathway (GO:2001234) 228 0 .07 - < 0.01 1.00E00 1.00E00 regulation of apoptotic signaling pathway (GO:2001233) 379 0 .11 - < 0.01 1.00E00 1.00E00 rhombomere structural organization (GO:0021595) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere formation (GO:0021594) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere morphogenesis (GO:0021593) 3 0 .00 - < 0.01 1.00E00 1.00E00 fourth ventricle development (GO:0021592) 1 0 .00 - < 0.01 1.00E00 1.00E00 ventricular system development (GO:0021591) 33 0 .01 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate biosynthetic process, mevalonate pathway (GO:0019287) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum maturation (GO:0021590) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to plasma membrane (GO:1903078) 64 0 .02 - < 0.01 1.00E00 1.00E00 glycine betaine biosynthetic process from choline (GO:0019285) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to plasma membrane (GO:1903077) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to plasma membrane (GO:1903076) 117 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of death-inducing signaling complex assembly (GO:1903073) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of death-inducing signaling complex assembly (GO:1903072) 1 0 .00 - < 0.01 1.00E00 1.00E00 unsaturated fatty acid metabolic process (GO:0033559) 105 0 .03 - < 0.01 1.00E00 1.00E00 multicellular organismal response to stress (GO:0033555) 89 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to stress (GO:0033554) 1642 0 .48 - < 0.01 1.00E00 1.00E00 response to vitamin B3 (GO:0033552) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chloride transport (GO:2001226) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum structural organization (GO:0021589) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chloride transport (GO:2001225) 6 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum formation (GO:0021588) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuron migration (GO:2001224) 18 0 .01 - < 0.01 1.00E00 1.00E00 cerebellum morphogenesis (GO:0021587) 45 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of neuron migration (GO:2001223) 12 0 .00 - < 0.01 1.00E00 1.00E00 pons maturation (GO:0021586) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron migration (GO:2001222) 52 0 .02 - < 0.01 1.00E00 1.00E00 UDP-N-acetylgalactosamine metabolic process (GO:0019276) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of reverse cholesterol transport (GO:1903064) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of reverse cholesterol transport (GO:1903062) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein lipidation (GO:1903061) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein lipidation (GO:1903060) 2 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) 13 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain maturation (GO:0021578) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vasculogenesis (GO:2001214) 12 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain structural organization (GO:0021577) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vasculogenesis (GO:2001213) 1 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain formation (GO:0021576) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vasculogenesis (GO:2001212) 16 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain morphogenesis (GO:0021575) 48 0 .01 - < 0.01 1.00E00 1.00E00 rhombomere 6 development (GO:0021572) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 5 development (GO:0021571) 3 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 4 development (GO:0021570) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein lipidation (GO:1903059) 8 0 .00 - < 0.01 1.00E00 1.00E00 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure (GO:0001999) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process, by transamination of glyoxylate (GO:0019265) 2 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure (GO:0001998) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process from serine (GO:0019264) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of melanosome organization (GO:1903056) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of the force of heart contraction by epinephrine-norepinephrine (GO:0001997) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular matrix organization (GO:1903055) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate by epinephrine-norepinephrine (GO:0001996) 3 0 .00 - < 0.01 1.00E00 1.00E00 N-acetylneuraminate catabolic process (GO:0019262) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of extracellular matrix organization (GO:1903054) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extracellular matrix organization (GO:1903053) 63 0 .02 - < 0.01 1.00E00 1.00E00 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure (GO:0001994) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proteolysis involved in protein catabolic process (GO:1903052) 139 0 .04 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by norepinephrine-epinephrine (GO:0001993) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of proteolysis involved in protein catabolic process (GO:1903051) 71 0 .02 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by vasopressin (GO:0001992) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proteolysis involved in protein catabolic process (GO:1903050) 237 0 .07 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by circulatory renin-angiotensin (GO:0001991) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by hormone (GO:0001990) 41 0 .01 - < 0.01 1.00E00 1.00E00 vitellogenesis (GO:0007296) 4 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid beta-oxidation using acyl-CoA dehydrogenase (GO:0033539) 11 0 .00 - < 0.01 1.00E00 1.00E00 female gamete generation (GO:0007292) 166 0 .05 - < 0.01 1.00E00 1.00E00 sperm individualization (GO:0007291) 2 0 .00 - < 0.01 1.00E00 1.00E00 spermatid nucleus elongation (GO:0007290) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of osteoclast development (GO:2001206) 4 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 3 development (GO:0021569) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of osteoclast development (GO:2001205) 5 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere 2 development (GO:0021568) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of osteoclast development (GO:2001204) 11 0 .00 - < 0.01 1.00E00 1.00E00 hypoglossal nerve development (GO:0021566) 1 0 .00 - < 0.01 1.00E00 1.00E00 vagus nerve development (GO:0021564) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell differentiation (GO:2001200) 4 0 .00 - < 0.01 1.00E00 1.00E00 glossopharyngeal nerve development (GO:0021563) 5 0 .00 - < 0.01 1.00E00 1.00E00 vestibulocochlear nerve development (GO:0021562) 11 0 .00 - < 0.01 1.00E00 1.00E00 facial nerve development (GO:0021561) 11 0 .00 - < 0.01 1.00E00 1.00E00 abducens nerve development (GO:0021560) 2 0 .00 - < 0.01 1.00E00 1.00E00 glucose 1-phosphate metabolic process (GO:0019255) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic cell cycle process (GO:1903047) 512 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure (GO:0001988) 1 0 .00 - < 0.01 1.00E00 1.00E00 carnitine metabolic process, CoA-linked (GO:0019254) 3 0 .00 - < 0.01 1.00E00 1.00E00 meiotic cell cycle process (GO:1903046) 195 0 .06 - < 0.01 1.00E00 1.00E00 protein localization to membrane raft (GO:1903044) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure (GO:0001985) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte hypertrophy (GO:1903043) 1 0 .00 - < 0.01 1.00E00 1.00E00 artery vasodilation involved in baroreceptor response to increased systemic arterial blood pressure (GO:0001984) 1 0 .00 - < 0.01 1.00E00 1.00E00 baroreceptor response to increased systemic arterial blood pressure (GO:0001983) 2 0 .00 - < 0.01 1.00E00 1.00E00 spermatid nucleus differentiation (GO:0007289) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of chondrocyte hypertrophy (GO:1903041) 1 0 .00 - < 0.01 1.00E00 1.00E00 baroreceptor response to decreased systemic arterial blood pressure (GO:0001982) 1 0 .00 - < 0.01 1.00E00 1.00E00 sperm axoneme assembly (GO:0007288) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by ischemic conditions (GO:0001980) 2 0 .00 - < 0.01 1.00E00 1.00E00 spermatid development (GO:0007286) 230 0 .07 - < 0.01 1.00E00 1.00E00 spermatogonial cell division (GO:0007284) 3 0 .00 - < 0.01 1.00E00 1.00E00 spermatogenesis (GO:0007283) 657 0 .19 - < 0.01 1.00E00 1.00E00 germ cell development (GO:0007281) 383 0 .11 - < 0.01 1.00E00 1.00E00 trigeminal nerve development (GO:0021559) 13 0 .00 - < 0.01 1.00E00 1.00E00 trochlear nerve development (GO:0021558) 2 0 .00 - < 0.01 1.00E00 1.00E00 oculomotor nerve development (GO:0021557) 4 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system formation (GO:0021556) 1 0 .00 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary morphogenesis (GO:0021555) 3 0 .00 - < 0.01 1.00E00 1.00E00 optic nerve development (GO:0021554) 22 0 .01 - < 0.01 1.00E00 1.00E00 olfactory nerve development (GO:0021553) 7 0 .00 - < 0.01 1.00E00 1.00E00 lactate biosynthetic process (GO:0019249) 4 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system morphogenesis (GO:0021551) 3 0 .00 - < 0.01 1.00E00 1.00E00 medulla oblongata development (GO:0021550) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte cell-cell adhesion (GO:1903039) 283 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte cell-cell adhesion (GO:1903038) 145 0 .04 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by chemoreceptor signaling (GO:0001979) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte cell-cell adhesion (GO:1903037) 384 0 .11 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback (GO:0001978) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactate biosynthetic process from pyruvate (GO:0019244) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of response to wounding (GO:1903036) 75 0 .02 - < 0.01 1.00E00 1.00E00 renal system process involved in regulation of blood volume (GO:0001977) 15 0 .00 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione (GO:0019243) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to wounding (GO:1903035) 91 0 .03 - < 0.01 1.00E00 1.00E00 nervous system process involved in regulation of systemic arterial blood pressure (GO:0001976) 15 0 .00 - < 0.01 1.00E00 1.00E00 methylglyoxal biosynthetic process (GO:0019242) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to wounding (GO:1903034) 170 0 .05 - < 0.01 1.00E00 1.00E00 response to amphetamine (GO:0001975) 36 0 .01 - < 0.01 1.00E00 1.00E00 blood vessel remodeling (GO:0001974) 39 0 .01 - < 0.01 1.00E00 1.00E00 citrulline biosynthetic process (GO:0019240) 4 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled adenosine receptor signaling pathway (GO:0001973) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of activation of membrane attack complex (GO:0001971) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of activation of membrane attack complex (GO:0001970) 2 0 .00 - < 0.01 1.00E00 1.00E00 gamete generation (GO:0007276) 838 0 .24 - < 0.01 1.00E00 1.00E00 multicellular organism development (GO:0007275) 4001 3 1.17 + 2.57 9.21E-02 1.00E00 neuromuscular synaptic transmission (GO:0007274) 28 0 .01 - < 0.01 1.00E00 1.00E00 ensheathment of neurons (GO:0007272) 133 0 .04 - < 0.01 1.00E00 1.00E00 synaptic transmission, cholinergic (GO:0007271) 27 0 .01 - < 0.01 1.00E00 1.00E00 neuron-neuron synaptic transmission (GO:0007270) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process to acetyl-CoA via L-pipecolate (GO:0033514) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine catabolic process to acetyl-CoA via saccharopine (GO:0033512) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum development (GO:0021549) 107 0 .03 - < 0.01 1.00E00 1.00E00 pons development (GO:0021548) 11 0 .00 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary initiation (GO:0021547) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhombomere development (GO:0021546) 8 0 .00 - < 0.01 1.00E00 1.00E00 cranial nerve development (GO:0021545) 65 0 .02 - < 0.01 1.00E00 1.00E00 subpallium development (GO:0021544) 28 0 .01 - < 0.01 1.00E00 1.00E00 pallium development (GO:0021543) 197 0 .06 - < 0.01 1.00E00 1.00E00 dentate gyrus development (GO:0021542) 27 0 .01 - < 0.01 1.00E00 1.00E00 ammon gyrus development (GO:0021541) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric glomerulus development (GO:0072298) 3 0 .00 - < 0.01 1.00E00 1.00E00 corpus callosum morphogenesis (GO:0021540) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to pheromone (GO:0019236) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of opsonization (GO:1903028) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of activation of membrane attack complex (GO:0001969) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of opsonization (GO:1903027) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903026) 2 0 .00 - < 0.01 1.00E00 1.00E00 suckling behavior (GO:0001967) 12 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of pain (GO:0019233) 67 0 .02 - < 0.01 1.00E00 1.00E00 regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1903025) 6 0 .00 - < 0.01 1.00E00 1.00E00 thigmotaxis (GO:0001966) 3 0 .00 - < 0.01 1.00E00 1.00E00 startle response (GO:0001964) 28 0 .01 - < 0.01 1.00E00 1.00E00 proprioception (GO:0019230) 5 0 .00 - < 0.01 1.00E00 1.00E00 synaptic transmission, dopaminergic (GO:0001963) 17 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter secretion (GO:0007269) 86 0 .03 - < 0.01 1.00E00 1.00E00 chemical synaptic transmission (GO:0007268) 417 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of glycoprotein metabolic process (GO:1903020) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cytokine-mediated signaling pathway (GO:0001961) 60 0 .02 - < 0.01 1.00E00 1.00E00 cell-cell signaling (GO:0007267) 845 0 .25 - < 0.01 1.00E00 1.00E00 negative regulation of cytokine-mediated signaling pathway (GO:0001960) 84 0 .02 - < 0.01 1.00E00 1.00E00 Rho protein signal transduction (GO:0007266) 63 0 .02 - < 0.01 1.00E00 1.00E00 Ras protein signal transduction (GO:0007265) 78 0 .02 - < 0.01 1.00E00 1.00E00 small GTPase-mediated signal transduction (GO:0007264) 262 0 .08 - < 0.01 1.00E00 1.00E00 nitric oxide mediated signal transduction (GO:0007263) 20 0 .01 - < 0.01 1.00E00 1.00E00 floor plate morphogenesis (GO:0033505) 4 0 .00 - < 0.01 1.00E00 1.00E00 tyrosine phosphorylation of STAT protein (GO:0007260) 6 0 .00 - < 0.01 1.00E00 1.00E00 floor plate development (GO:0033504) 11 0 .00 - < 0.01 1.00E00 1.00E00 carbohydrate homeostasis (GO:0033500) 207 0 .06 - < 0.01 1.00E00 1.00E00 subthalamus development (GO:0021539) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithalamus development (GO:0021538) 3 0 .00 - < 0.01 1.00E00 1.00E00 telencephalon development (GO:0021537) 283 0 .08 - < 0.01 1.00E00 1.00E00 diencephalon development (GO:0021536) 82 0 .02 - < 0.01 1.00E00 1.00E00 cell migration in hindbrain (GO:0021535) 17 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation in hindbrain (GO:0021534) 8 0 .00 - < 0.01 1.00E00 1.00E00 cell differentiation in hindbrain (GO:0021533) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of vasoconstriction (GO:0019229) 68 0 .02 - < 0.01 1.00E00 1.00E00 neural tube patterning (GO:0021532) 31 0 .01 - < 0.01 1.00E00 1.00E00 metanephric nephron tubule formation (GO:0072289) 4 0 .00 - < 0.01 1.00E00 1.00E00 neuronal action potential (GO:0019228) 35 0 .01 - < 0.01 1.00E00 1.00E00 neuronal action potential propagation (GO:0019227) 10 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord oligodendrocyte cell fate specification (GO:0021530) 3 0 .00 - < 0.01 1.00E00 1.00E00 metanephric distal tubule morphogenesis (GO:0072287) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glycoprotein metabolic process (GO:1903019) 15 0 .00 - < 0.01 1.00E00 1.00E00 transmission of nerve impulse (GO:0019226) 66 0 .02 - < 0.01 1.00E00 1.00E00 metanephric connecting tubule development (GO:0072286) 1 0 .00 - < 0.01 1.00E00 1.00E00 siRNA-mediated post-transcriptional gene silencing (GO:0140766) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glycoprotein metabolic process (GO:1903018) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cytokine-mediated signaling pathway (GO:0001959) 168 0 .05 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in metanephric renal vesicle formation (GO:0072285) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of exo-alpha-sialidase activity (GO:1903017) 1 0 .00 - < 0.01 1.00E00 1.00E00 endochondral ossification (GO:0001958) 32 0 .01 - < 0.01 1.00E00 1.00E00 metanephric S-shaped body morphogenesis (GO:0072284) 4 0 .00 - < 0.01 1.00E00 1.00E00 intramembranous ossification (GO:0001957) 7 0 .00 - < 0.01 1.00E00 1.00E00 metanephric renal vesicle morphogenesis (GO:0072283) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurotransmitter secretion (GO:0001956) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of metabolic process (GO:0019222) 6356 0 1.85 - < 0.01 1.87E-01 1.00E00 metanephric nephron tubule morphogenesis (GO:0072282) 8 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel maturation (GO:0001955) 8 0 .00 - < 0.01 1.00E00 1.00E00 cytokine-mediated signaling pathway (GO:0019221) 430 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of cell-matrix adhesion (GO:0001954) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of phosphate metabolic process (GO:0019220) 697 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of bone development (GO:1903012) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell-matrix adhesion (GO:0001953) 36 0 .01 - < 0.01 1.00E00 1.00E00 cell surface receptor signaling pathway via JAK-STAT (GO:0007259) 61 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of bone development (GO:1903011) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell-matrix adhesion (GO:0001952) 123 0 .04 - < 0.01 1.00E00 1.00E00 JUN phosphorylation (GO:0007258) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bone development (GO:1903010) 10 0 .00 - < 0.01 1.00E00 1.00E00 intestinal D-glucose absorption (GO:0001951) 4 0 .00 - < 0.01 1.00E00 1.00E00 JNK cascade (GO:0007254) 79 0 .02 - < 0.01 1.00E00 1.00E00 I-kappaB phosphorylation (GO:0007252) 7 0 .00 - < 0.01 1.00E00 1.00E00 activation of NF-kappaB-inducing kinase activity (GO:0007250) 10 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord oligodendrocyte cell differentiation (GO:0021529) 5 0 .00 - < 0.01 1.00E00 1.00E00 commissural neuron differentiation in spinal cord (GO:0021528) 1 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord association neuron differentiation (GO:0021527) 12 0 .00 - < 0.01 1.00E00 1.00E00 medial motor column neuron differentiation (GO:0021526) 2 0 .00 - < 0.01 1.00E00 1.00E00 visceral motor neuron differentiation (GO:0021524) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amniotic stem cell differentiation (GO:2000798) 1 0 .00 - < 0.01 1.00E00 1.00E00 somatic motor neuron differentiation (GO:0021523) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amniotic stem cell differentiation (GO:2000797) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleobase-containing compound metabolic process (GO:0019219) 4050 0 1.18 - < 0.01 6.05E-01 1.00E00 spinal cord motor neuron differentiation (GO:0021522) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of steroid metabolic process (GO:0019218) 105 0 .03 - < 0.01 1.00E00 1.00E00 ventral spinal cord interneuron specification (GO:0021521) 7 0 .00 - < 0.01 1.00E00 1.00E00 metanephric comma-shaped body morphogenesis (GO:0072278) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell proliferation involved in lung morphogenesis (GO:2000795) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fatty acid metabolic process (GO:0019217) 99 0 .03 - < 0.01 1.00E00 1.00E00 spinal cord motor neuron cell fate specification (GO:0021520) 10 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerular capillary formation (GO:0072277) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell proliferation involved in lung morphogenesis (GO:2000794) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipid metabolic process (GO:0019216) 325 0 .09 - < 0.01 1.00E00 1.00E00 metanephric glomerulus vasculature morphogenesis (GO:0072276) 3 0 .00 - < 0.01 1.00E00 1.00E00 organelle disassembly (GO:1903008) 72 0 .02 - < 0.01 1.00E00 1.00E00 cell proliferation involved in heart valve development (GO:2000793) 1 0 .00 - < 0.01 1.00E00 1.00E00 sebaceous gland cell differentiation (GO:0001949) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerulus morphogenesis (GO:0072275) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Lys63-specific deubiquitinase activity (GO:1903007) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerular basement membrane development (GO:0072274) 1 0 .00 - < 0.01 1.00E00 1.00E00 reorganization of cellular membranes to establish viral sites of replication (GO:0140754) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein K63-linked deubiquitination (GO:1903006) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation involved in lung development (GO:2000791) 2 0 .00 - < 0.01 1.00E00 1.00E00 heart looping (GO:0001947) 64 0 .02 - < 0.01 1.00E00 1.00E00 metanephric nephron morphogenesis (GO:0072273) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation involved in lung development (GO:2000790) 2 0 .00 - < 0.01 1.00E00 1.00E00 lymphangiogenesis (GO:0001946) 15 0 .00 - < 0.01 1.00E00 1.00E00 proximal/distal pattern formation involved in metanephric nephron development (GO:0072272) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein K63-linked deubiquitination (GO:1903004) 2 0 .00 - < 0.01 1.00E00 1.00E00 lymph vessel development (GO:0001945) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein deubiquitination (GO:1903003) 5 0 .00 - < 0.01 1.00E00 1.00E00 vasculature development (GO:0001944) 558 0 .16 - < 0.01 1.00E00 1.00E00 positive regulation of lipid transport across blood-brain barrier (GO:1903002) 1 0 .00 - < 0.01 1.00E00 1.00E00 canonical NF-kappaB signal transduction (GO:0007249) 41 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipid transport across blood-brain barrier (GO:1903001) 1 0 .00 - < 0.01 1.00E00 1.00E00 hair follicle development (GO:0001942) 83 0 .02 - < 0.01 1.00E00 1.00E00 regulation of lipid transport across blood-brain barrier (GO:1903000) 1 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic membrane organization (GO:0001941) 27 0 .01 - < 0.01 1.00E00 1.00E00 ventral spinal cord development (GO:0021517) 45 0 .01 - < 0.01 1.00E00 1.00E00 dorsal spinal cord development (GO:0021516) 20 0 .01 - < 0.01 1.00E00 1.00E00 cell differentiation in spinal cord (GO:0021515) 50 0 .01 - < 0.01 1.00E00 1.00E00 ventral spinal cord interneuron differentiation (GO:0021514) 13 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord dorsal/ventral patterning (GO:0021513) 16 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord anterior/posterior patterning (GO:0021512) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of autophagosome assembly (GO:2000786) 20 0 .01 - < 0.01 1.00E00 1.00E00 spinal cord patterning (GO:0021511) 18 0 .01 - < 0.01 1.00E00 1.00E00 pattern specification involved in metanephros development (GO:0072268) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of autophagosome assembly (GO:2000785) 49 0 .01 - < 0.01 1.00E00 1.00E00 spinal cord development (GO:0021510) 100 0 .03 - < 0.01 1.00E00 1.00E00 metanephric capsule specification (GO:0072267) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric capsule formation (GO:0072266) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric capsule morphogenesis (GO:0072265) 1 0 .00 - < 0.01 1.00E00 1.00E00 siRNA transcription (GO:0140745) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell proliferation (GO:0001938) 90 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of lncRNA transcription (GO:0140744) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of double-strand break repair (GO:2000781) 98 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell proliferation (GO:0001937) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lncRNA transcription (GO:0140743) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of double-strand break repair (GO:2000780) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell proliferation (GO:0001936) 132 0 .04 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell proliferation involved in metanephros development (GO:0072262) 1 0 .00 - < 0.01 1.00E00 1.00E00 lncRNA transcription (GO:0140742) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell proliferation (GO:0001935) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein phosphorylation (GO:0001934) 310 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of protein phosphorylation (GO:0001933) 157 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of sarcomere organization (GO:0060299) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein phosphorylation (GO:0001932) 507 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of sarcomere organization (GO:0060298) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sarcomere organization (GO:0060297) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium beat frequency involved in ciliary motility (GO:0060296) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium movement involved in cell motility (GO:0060295) 33 0 .01 - < 0.01 1.00E00 1.00E00 cilium movement involved in cell motility (GO:0060294) 195 0 .06 - < 0.01 1.00E00 1.00E00 long-term synaptic depression (GO:0060292) 20 0 .01 - < 0.01 1.00E00 1.00E00 osmosensory signaling pathway (GO:0007231) 9 0 .00 - < 0.01 1.00E00 1.00E00 long-term synaptic potentiation (GO:0060291) 57 0 .02 - < 0.01 1.00E00 1.00E00 transdifferentiation (GO:0060290) 7 0 .00 - < 0.01 1.00E00 1.00E00 roof plate formation (GO:0021509) 1 0 .00 - < 0.01 1.00E00 1.00E00 floor plate formation (GO:0021508) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of double-strand break repair (GO:2000779) 147 0 .04 - < 0.01 1.00E00 1.00E00 neural fold bending (GO:0021503) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural fold elevation formation (GO:0021502) 3 0 .00 - < 0.01 1.00E00 1.00E00 metanephric interstitial fibroblast development (GO:0072259) 1 0 .00 - < 0.01 1.00E00 1.00E00 NLRP6 inflammasome complex assembly (GO:0140739) 1 0 .00 - < 0.01 1.00E00 1.00E00 prechordal plate formation (GO:0021501) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric interstitial fibroblast differentiation (GO:0072258) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular senescence (GO:2000774) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular senescence (GO:2000773) 22 0 .01 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell development (GO:0072255) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular senescence (GO:2000772) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of exocyst assembly (GO:0001928) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangial cell differentiation (GO:0072254) 2 0 .00 - < 0.01 1.00E00 1.00E00 B-1 B cell differentiation (GO:0001923) 5 0 .00 - < 0.01 1.00E00 1.00E00 integrin-mediated signaling pathway (GO:0007229) 96 0 .03 - < 0.01 1.00E00 1.00E00 B-1 B cell homeostasis (GO:0001922) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor recycling (GO:0001921) 14 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor recycling (GO:0001920) 5 0 .00 - < 0.01 1.00E00 1.00E00 patched ligand maturation (GO:0007225) 1 0 .00 - < 0.01 1.00E00 1.00E00 cilium-dependent cell motility (GO:0060285) 198 0 .06 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway (GO:0007224) 92 0 .03 - < 0.01 1.00E00 1.00E00 regulation of cell development (GO:0060284) 816 0 .24 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway, calcium modulating pathway (GO:0007223) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oocyte development (GO:0060283) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oocyte development (GO:0060282) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription of Notch receptor target (GO:0007221) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oocyte development (GO:0060281) 3 0 .00 - < 0.01 1.00E00 1.00E00 Notch receptor processing (GO:0007220) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ovulation (GO:0060280) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nephron tubule epithelial cell differentiation (GO:2000768) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic translation (GO:2000767) 16 0 .00 - < 0.01 1.00E00 1.00E00 metanephric podocyte development (GO:0072249) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic translation (GO:2000766) 10 0 .00 - < 0.01 1.00E00 1.00E00 metanephric podocyte differentiation (GO:0072248) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translation (GO:2000765) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of receptor recycling (GO:0001919) 25 0 .01 - < 0.01 1.00E00 1.00E00 metanephric glomerular epithelium development (GO:0072244) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric nephron epithelium development (GO:0072243) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated cytotoxicity (GO:0001916) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of T cell mediated cytotoxicity (GO:0001915) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated cytotoxicity (GO:0001914) 48 0 .01 - < 0.01 1.00E00 1.00E00 metanephric DCT cell differentiation (GO:0072240) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell mediated cytotoxicity (GO:0001913) 17 0 .00 - < 0.01 1.00E00 1.00E00 Notch signaling pathway (GO:0007219) 117 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of ovulation (GO:0060279) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte mediated cytotoxicity (GO:0001912) 67 0 .02 - < 0.01 1.00E00 1.00E00 neuropeptide signaling pathway (GO:0007218) 113 0 .03 - < 0.01 1.00E00 1.00E00 regulation of ovulation (GO:0060278) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte mediated cytotoxicity (GO:0001911) 32 0 .01 - < 0.01 1.00E00 1.00E00 tachykinin receptor signaling pathway (GO:0007217) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte mediated cytotoxicity (GO:0001910) 99 0 .03 - < 0.01 1.00E00 1.00E00 G protein-coupled glutamate receptor signaling pathway (GO:0007216) 15 0 .00 - < 0.01 1.00E00 1.00E00 glutamate receptor signaling pathway (GO:0007215) 50 0 .01 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid signaling pathway (GO:0007214) 30 0 .01 - < 0.01 1.00E00 1.00E00 G protein-coupled acetylcholine receptor signaling pathway (GO:0007213) 21 0 .01 - < 0.01 1.00E00 1.00E00 G protein-coupled dopamine receptor signaling pathway (GO:0007212) 26 0 .01 - < 0.01 1.00E00 1.00E00 embryonic skeletal joint morphogenesis (GO:0060272) 12 0 .00 - < 0.01 1.00E00 1.00E00 cilium assembly (GO:0060271) 350 0 .10 - < 0.01 1.00E00 1.00E00 serotonin receptor signaling pathway (GO:0007210) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-lysine acetylation (GO:2000758) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-lysine acetylation (GO:2000757) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerulus vasculature development (GO:0072239) 7 0 .00 - < 0.01 1.00E00 1.00E00 constitutive heterochromatin formation (GO:0140719) 59 0 .02 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-lysine acetylation (GO:2000756) 6 0 .00 - < 0.01 1.00E00 1.00E00 facultative heterochromatin formation (GO:0140718) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sphingomyelin catabolic process (GO:2000755) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric proximal tubule development (GO:0072237) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sphingomyelin catabolic process (GO:2000754) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric loop of Henle development (GO:0072236) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucosylceramide catabolic process (GO:2000753) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte mediated cytotoxicity (GO:0001909) 76 0 .02 - < 0.01 1.00E00 1.00E00 metanephric distal tubule development (GO:0072235) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucosylceramide catabolic process (GO:2000752) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric nephron tubule development (GO:0072234) 18 0 .01 - < 0.01 1.00E00 1.00E00 metanephric thick ascending limb development (GO:0072233) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell killing (GO:0001906) 176 0 .05 - < 0.01 1.00E00 1.00E00 metanephric proximal convoluted tubule segment 2 development (GO:0072232) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric proximal straight tubule development (GO:0072230) 1 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating serotonin receptor signaling pathway (GO:0007208) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of respiratory burst (GO:0060268) 6 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway (GO:0007207) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of respiratory burst (GO:0060267) 9 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating G protein-coupled glutamate receptor signaling pathway (GO:0007206) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of respiratory burst involved in inflammatory response (GO:0060266) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of respiratory burst involved in inflammatory response (GO:0060265) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytosolic calcium ion concentration (GO:0007204) 165 0 .05 - < 0.01 1.00E00 1.00E00 regulation of respiratory burst involved in inflammatory response (GO:0060264) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of respiratory burst (GO:0060263) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of N-terminal protein palmitoylation (GO:0060262) 1 0 .00 - < 0.01 1.00E00 1.00E00 cyclic purine nucleotide metabolic process (GO:0052652) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transcription initiation by RNA polymerase II (GO:0060261) 62 0 .02 - < 0.01 1.00E00 1.00E00 phospholipase C-activating G protein-coupled receptor signaling pathway (GO:0007200) 135 0 .04 - < 0.01 1.00E00 1.00E00 monoacylglycerol catabolic process (GO:0052651) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription initiation by RNA polymerase II (GO:0060260) 73 0 .02 - < 0.01 1.00E00 1.00E00 metanephric proximal convoluted tubule development (GO:0072229) 2 0 .00 - < 0.01 1.00E00 1.00E00 CAT tailing (GO:0140708) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric macula densa development (GO:0072227) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anterior head development (GO:2000744) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein-containing complex localization to centriolar satellite (GO:0140706) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anterior head development (GO:2000742) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerulus development (GO:0072224) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal stem cell differentiation (GO:2000741) 5 0 .00 - < 0.01 1.00E00 1.00E00 metanephric glomerular mesangium development (GO:0072223) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal stem cell differentiation (GO:2000740) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric distal convoluted tubule development (GO:0072221) 5 0 .00 - < 0.01 1.00E00 1.00E00 metanephric descending thin limb development (GO:0072220) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of feeding behavior (GO:0060259) 26 0 .01 - < 0.01 1.00E00 1.00E00 alditol phosphate metabolic process (GO:0052646) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macromolecule metabolic process (GO:0060255) 5809 0 1.69 - < 0.01 1.94E-01 1.00E00 regulation of N-terminal protein palmitoylation (GO:0060254) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell proliferation (GO:0060253) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell proliferation (GO:0060252) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glial cell proliferation (GO:0060251) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal stem cell differentiation (GO:2000739) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of stem cell differentiation (GO:2000738) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of stem cell differentiation (GO:2000737) 27 0 .01 - < 0.01 1.00E00 1.00E00 metanephric cortical collecting duct development (GO:0072219) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stem cell differentiation (GO:2000736) 83 0 .02 - < 0.01 1.00E00 1.00E00 metanephric ascending thin limb development (GO:0072218) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metanephros development (GO:0072217) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation (GO:2000734) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metanephros development (GO:0072216) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation (GO:2000733) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephros development (GO:0072215) 6 0 .00 - < 0.01 1.00E00 1.00E00 metanephric cortex development (GO:0072214) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium import into the mitochondrion (GO:0110099) 3 0 .00 - < 0.01 1.00E00 1.00E00 metanephric capsule development (GO:0072213) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase I transcription (GO:2000730) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium import into the mitochondrion (GO:0110097) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to aldehyde (GO:0110096) 18 0 .01 - < 0.01 1.00E00 1.00E00 metanephric nephron development (GO:0072210) 32 0 .01 - < 0.01 1.00E00 1.00E00 cellular detoxification of aldehyde (GO:0110095) 9 0 .00 - < 0.01 1.00E00 1.00E00 anatomical structure homeostasis (GO:0060249) 234 0 .07 - < 0.01 1.00E00 1.00E00 negative regulation of hippocampal neuron apoptotic process (GO:0110091) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear cell cycle DNA replication (GO:1902576) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of cell density (GO:0060245) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in contact inhibition (GO:0060244) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell growth involved in contact inhibition (GO:0060243) 1 0 .00 - < 0.01 1.00E00 1.00E00 contact inhibition (GO:0060242) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of serine-type peptidase activity (GO:1902572) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to nucleolus (GO:1902570) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal cell proliferation involved in ureter development (GO:2000729) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell differentiation (GO:2000727) 8 0 .00 - < 0.01 1.00E00 1.00E00 metanephric mesangial cell differentiation (GO:0072209) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell differentiation (GO:2000726) 8 0 .00 - < 0.01 1.00E00 1.00E00 metanephric smooth muscle tissue development (GO:0072208) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell differentiation (GO:2000725) 16 0 .00 - < 0.01 1.00E00 1.00E00 metanephric epithelium development (GO:0072207) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac vascular smooth muscle cell differentiation (GO:2000724) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric juxtaglomerular apparatus development (GO:0072206) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac vascular smooth muscle cell differentiation (GO:2000723) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric collecting duct development (GO:0072205) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac vascular smooth muscle cell differentiation (GO:2000722) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hippocampal neuron apoptotic process (GO:0110089) 5 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation involved in metanephros development (GO:0072203) 7 0 .00 - < 0.01 1.00E00 1.00E00 hippocampal neuron apoptotic process (GO:0110088) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric (GO:2000720) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell differentiation involved in metanephros development (GO:0072202) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation (GO:0072201) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell proliferation involved in ureter development (GO:0072200) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil activation (GO:1902567) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic spindle organization (GO:0060236) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of eosinophil activation (GO:1902566) 1 0 .00 - < 0.01 1.00E00 1.00E00 lens induction in camera-type eye (GO:0060235) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil activation (GO:1902565) 3 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast delamination (GO:0060234) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil activation (GO:1902564) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil activation (GO:1902563) 11 0 .00 - < 0.01 1.00E00 1.00E00 delamination (GO:0060232) 7 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition (GO:0060231) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric (GO:2000719) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion, centromeric (GO:2000718) 2 0 .00 - < 0.01 1.00E00 1.00E00 vesicle-mediated intercellular transport (GO:0110077) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ferroptosis (GO:0110076) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ferroptosis (GO:0110075) 12 0 .00 - < 0.01 1.00E00 1.00E00 3'-phospho-5'-adenylyl sulfate transmembrane transport (GO:1902559) 2 0 .00 - < 0.01 1.00E00 1.00E00 5'-adenylyl sulfate transmembrane transport (GO:1902558) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of catalase activity (GO:1902553) 1 0 .00 - < 0.01 1.00E00 1.00E00 retinal rod cell differentiation (GO:0060221) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of catalase activity (GO:1902551) 1 0 .00 - < 0.01 1.00E00 1.00E00 camera-type eye photoreceptor cell fate commitment (GO:0060220) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphate-containing compound metabolic process (GO:0006796) 1459 0 .43 - < 0.01 1.00E00 1.00E00 phosphorus metabolic process (GO:0006793) 1462 0 .43 - < 0.01 1.00E00 1.00E00 sulfur compound metabolic process (GO:0006790) 317 0 .09 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule biogenesis (GO:2000707) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dense core granule biogenesis (GO:2000706) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dense core granule biogenesis (GO:2000705) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation (GO:2000703) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation (GO:2000702) 1 0 .00 - < 0.01 1.00E00 1.00E00 camera-type eye photoreceptor cell differentiation (GO:0060219) 33 0 .01 - < 0.01 1.00E00 1.00E00 lncRNA catabolic process (GO:0110064) 2 0 .00 - < 0.01 1.00E00 1.00E00 hematopoietic stem cell differentiation (GO:0060218) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of angiotensin-activated signaling pathway (GO:0110063) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902548) 14 0 .00 - < 0.01 1.00E00 1.00E00 hemangioblast cell differentiation (GO:0060217) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of angiotensin-activated signaling pathway (GO:0110062) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) 30 0 .01 - < 0.01 1.00E00 1.00E00 definitive hemopoiesis (GO:0060216) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of angiotensin-activated signaling pathway (GO:0110061) 4 0 .00 - < 0.01 1.00E00 1.00E00 primitive hemopoiesis (GO:0060215) 8 0 .00 - < 0.01 1.00E00 1.00E00 endocardium formation (GO:0060214) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060212) 3 0 .00 - < 0.01 1.00E00 1.00E00 bilirubin conjugation (GO:0006789) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211) 15 0 .00 - < 0.01 1.00E00 1.00E00 heme oxidation (GO:0006788) 2 0 .00 - < 0.01 1.00E00 1.00E00 porphyrin-containing compound catabolic process (GO:0006787) 13 0 .00 - < 0.01 1.00E00 1.00E00 heme B biosynthetic process (GO:0006785) 8 0 .00 - < 0.01 1.00E00 1.00E00 heme A biosynthetic process (GO:0006784) 10 0 .00 - < 0.01 1.00E00 1.00E00 heme biosynthetic process (GO:0006783) 25 0 .01 - < 0.01 1.00E00 1.00E00 protoporphyrinogen IX biosynthetic process (GO:0006782) 9 0 .00 - < 0.01 1.00E00 1.00E00 succinyl-CoA pathway (GO:0006781) 1 0 .00 - < 0.01 1.00E00 1.00E00 uroporphyrinogen III biosynthetic process (GO:0006780) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel endothelial cell differentiation (GO:0110059) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood vessel endothelial cell differentiation (GO:0110057) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin filament organization (GO:0110053) 266 0 .08 - < 0.01 1.00E00 1.00E00 metabolite repair (GO:0110051) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular signal transduction (GO:1902533) 1124 0 .33 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular signal transduction (GO:1902532) 692 0 .20 - < 0.01 1.00E00 1.00E00 porphyrin-containing compound biosynthetic process (GO:0006779) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of intracellular signal transduction (GO:1902531) 1975 0 .58 - < 0.01 1.00E00 1.00E00 porphyrin-containing compound metabolic process (GO:0006778) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein linear polyubiquitination (GO:1902530) 2 0 .00 - < 0.01 1.00E00 1.00E00 Mo-molybdopterin cofactor biosynthetic process (GO:0006777) 6 0 .00 - < 0.01 1.00E00 1.00E00 vitamin A metabolic process (GO:0006776) 8 0 .00 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin metabolic process (GO:0006775) 43 0 .01 - < 0.01 1.00E00 1.00E00 thiamine metabolic process (GO:0006772) 4 0 .00 - < 0.01 1.00E00 1.00E00 riboflavin metabolic process (GO:0006771) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin D stimulus (GO:0071799) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to prostaglandin D (GO:0071798) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein linear polyubiquitination (GO:1902528) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein monoubiquitination (GO:1902527) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein monoubiquitination (GO:1902525) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein K48-linked ubiquitination (GO:1902524) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein K63-linked ubiquitination (GO:1902523) 8 0 .00 - < 0.01 1.00E00 1.00E00 nicotinamide metabolic process (GO:0006769) 1 0 .00 - < 0.01 1.00E00 1.00E00 biotin metabolic process (GO:0006768) 4 0 .00 - < 0.01 1.00E00 1.00E00 water-soluble vitamin metabolic process (GO:0006767) 62 0 .02 - < 0.01 1.00E00 1.00E00 vitamin metabolic process (GO:0006766) 105 0 .03 - < 0.01 1.00E00 1.00E00 folic acid-containing compound metabolic process (GO:0006760) 26 0 .01 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network maintenance (GO:0071788) 1 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network formation (GO:0071787) 6 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network organization (GO:0071786) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of G2/MI transition of meiotic cell cycle (GO:0110032) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G2/MI transition of meiotic cell cycle (GO:0110031) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of G2/MI transition of meiotic cell cycle (GO:0110030) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1902514) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of organelle transport along microtubule (GO:1902513) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic DNA fragmentation (GO:1902512) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic DNA fragmentation (GO:1902511) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic DNA fragmentation (GO:1902510) 11 0 .00 - < 0.01 1.00E00 1.00E00 ATP biosynthetic process (GO:0006754) 84 0 .02 - < 0.01 1.00E00 1.00E00 nucleoside phosphate metabolic process (GO:0006753) 584 0 .17 - < 0.01 1.00E00 1.00E00 glutathione catabolic process (GO:0006751) 11 0 .00 - < 0.01 1.00E00 1.00E00 MHC class II protein complex assembly (GO:0002399) 16 0 .00 - < 0.01 1.00E00 1.00E00 glutathione biosynthetic process (GO:0006750) 14 0 .00 - < 0.01 1.00E00 1.00E00 MHC class Ib protein complex assembly (GO:0002398) 1 0 .00 - < 0.01 1.00E00 1.00E00 MHC class I protein complex assembly (GO:0002397) 6 0 .00 - < 0.01 1.00E00 1.00E00 MHC protein complex assembly (GO:0002396) 21 0 .01 - < 0.01 1.00E00 1.00E00 immune response in nasopharyngeal-associated lymphoid tissue (GO:0002395) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA strand resection involved in replication fork processing (GO:0110027) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA strand resection involved in replication fork processing (GO:0110026) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand resection involved in replication fork processing (GO:0110025) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle myoblast proliferation (GO:0110024) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to fibroblast growth factor (GO:0071774) 139 0 .04 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle myoblast proliferation (GO:0110022) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to BMP stimulus (GO:0071773) 95 0 .03 - < 0.01 1.00E00 1.00E00 response to BMP (GO:0071772) 95 0 .03 - < 0.01 1.00E00 1.00E00 regulation of actomyosin structure organization (GO:0110020) 101 0 .03 - < 0.01 1.00E00 1.00E00 glutathione metabolic process (GO:0006749) 56 0 .02 - < 0.01 1.00E00 1.00E00 FAD biosynthetic process (GO:0006747) 1 0 .00 - < 0.01 1.00E00 1.00E00 ubiquinone biosynthetic process (GO:0006744) 15 0 .00 - < 0.01 1.00E00 1.00E00 ubiquinone metabolic process (GO:0006743) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein branched polyubiquitination (GO:0141198) 19 0 .01 - < 0.01 1.00E00 1.00E00 NADP catabolic process (GO:0006742) 3 0 .00 - < 0.01 1.00E00 1.00E00 NADP biosynthetic process (GO:0006741) 2 0 .00 - < 0.01 1.00E00 1.00E00 transposable element silencing by piRNA-mediated DNA methylation (GO:0141196) 15 0 .00 - < 0.01 1.00E00 1.00E00 NADPH regeneration (GO:0006740) 17 0 .00 - < 0.01 1.00E00 1.00E00 immune response in gut-associated lymphoid tissue (GO:0002387) 4 0 .00 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated signaling pathway (GO:0141193) 104 0 .03 - < 0.01 1.00E00 1.00E00 mucosal immune response (GO:0002385) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of HRI-mediated signaling (GO:0141191) 2 0 .00 - < 0.01 1.00E00 1.00E00 hepatic immune response (GO:0002384) 2 0 .00 - < 0.01 1.00E00 1.00E00 immune response in brain or nervous system (GO:0002383) 1 0 .00 - < 0.01 1.00E00 1.00E00 immunoglobulin production involved in immunoglobulin-mediated immune response (GO:0002381) 31 0 .01 - < 0.01 1.00E00 1.00E00 cap-independent translational initiation of linear mRNA (GO:0110017) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear inner membrane organization (GO:0071765) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to P-body (GO:0110012) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear membrane organization (GO:0071763) 47 0 .01 - < 0.01 1.00E00 1.00E00 regulation of basement membrane organization (GO:0110011) 11 0 .00 - < 0.01 1.00E00 1.00E00 basolateral protein secretion (GO:0110010) 5 0 .00 - < 0.01 1.00E00 1.00E00 NADP metabolic process (GO:0006739) 39 0 .01 - < 0.01 1.00E00 1.00E00 nicotinamide riboside catabolic process (GO:0006738) 1 0 .00 - < 0.01 1.00E00 1.00E00 NADH metabolic process (GO:0006734) 40 0 .01 - < 0.01 1.00E00 1.00E00 nucleic acid catabolic process (GO:0141188) 190 0 .06 - < 0.01 1.00E00 1.00E00 nucleic acid biosynthetic process (GO:0141187) 1476 0 .43 - < 0.01 1.00E00 1.00E00 one-carbon metabolic process (GO:0006730) 23 0 .01 - < 0.01 1.00E00 1.00E00 immunoglobulin production (GO:0002377) 46 0 .01 - < 0.01 1.00E00 1.00E00 immune system process (GO:0002376) 2384 0 .70 - < 0.01 1.00E00 1.00E00 formin-nucleated actin cable organization (GO:0110009) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tRNA methylation (GO:0110002) 1 0 .00 - < 0.01 1.00E00 1.00E00 tetrahydrobiopterin biosynthetic process (GO:0006729) 7 0 .00 - < 0.01 1.00E00 1.00E00 eye pigment biosynthetic process (GO:0006726) 2 0 .00 - < 0.01 1.00E00 1.00E00 triterpenoid metabolic process (GO:0006722) 2 0 .00 - < 0.01 1.00E00 1.00E00 terpenoid metabolic process (GO:0006721) 102 1 .03 + 33.63 2.94E-02 1.00E00 isoprenoid metabolic process (GO:0006720) 122 1 .04 + 28.11 3.50E-02 1.00E00 gene silencing by piRNA-directed DNA methylation (GO:0141176) 15 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte activation involved in immune response (GO:0002366) 210 0 .06 - < 0.01 1.00E00 1.00E00 NK T cell lineage commitment (GO:0002364) 1 0 .00 - < 0.01 1.00E00 1.00E00 symbiont-mediated perturbation of host membrane (GO:0141171) 1 0 .00 - < 0.01 1.00E00 1.00E00 alpha-beta T cell lineage commitment (GO:0002363) 20 0 .01 - < 0.01 1.00E00 1.00E00 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment (GO:0002362) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0002361) 5 0 .00 - < 0.01 1.00E00 1.00E00 T cell lineage commitment (GO:0002360) 28 0 .01 - < 0.01 1.00E00 1.00E00 sesquiterpenoid metabolic process (GO:0006714) 3 0 .00 - < 0.01 1.00E00 1.00E00 glucocorticoid catabolic process (GO:0006713) 1 0 .00 - < 0.01 1.00E00 1.00E00 estrogen catabolic process (GO:0006711) 1 0 .00 - < 0.01 1.00E00 1.00E00 chromosomal 5-methylcytosine DNA demethylation, oxidation pathway (GO:0141167) 4 0 .00 - < 0.01 1.00E00 1.00E00 chromosomal 5-methylcytosine DNA demethylation pathway (GO:0141166) 8 0 .00 - < 0.01 1.00E00 1.00E00 B cell homeostatic proliferation (GO:0002358) 2 0 .00 - < 0.01 1.00E00 1.00E00 defense response to tumor cell (GO:0002357) 12 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial protein quality control (GO:0141164) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cAMP/PKA signal transduction (GO:0141163) 16 0 .00 - < 0.01 1.00E00 1.00E00 detection of tumor cell (GO:0002355) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cAMP/PKA signal transduction (GO:0141162) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cAMP/PKA signal transduction (GO:0141161) 28 0 .01 - < 0.01 1.00E00 1.00E00 plasma kallikrein-kinin cascade (GO:0002353) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell negative selection (GO:0002352) 2 0 .00 - < 0.01 1.00E00 1.00E00 serotonin production involved in inflammatory response (GO:0002351) 3 0 .00 - < 0.01 1.00E00 1.00E00 photoreceptor cell maintenance (GO:0045494) 45 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to nitric oxide (GO:0071732) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to nitric oxide (GO:0071731) 22 0 .01 - < 0.01 1.00E00 1.00E00 cholesterol catabolic process (GO:0006707) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell differentiation (GO:2001199) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell differentiation (GO:2001198) 13 0 .00 - < 0.01 1.00E00 1.00E00 mineralocorticoid biosynthetic process (GO:0006705) 4 0 .00 - < 0.01 1.00E00 1.00E00 glucocorticoid biosynthetic process (GO:0006704) 8 0 .00 - < 0.01 1.00E00 1.00E00 androgen biosynthetic process (GO:0006702) 9 0 .00 - < 0.01 1.00E00 1.00E00 progesterone biosynthetic process (GO:0006701) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gamma-delta T cell activation involved in immune response (GO:2001193) 1 0 .00 - < 0.01 1.00E00 1.00E00 histamine production involved in inflammatory response (GO:0002349) 5 0 .00 - < 0.01 1.00E00 1.00E00 C21-steroid hormone biosynthetic process (GO:0006700) 10 0 .00 - < 0.01 1.00E00 1.00E00 cAMP/PKA signal transduction (GO:0141156) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gamma-delta T cell activation involved in immune response (GO:2001191) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to tumor cell (GO:0002347) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001190) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell affinity maturation (GO:0002344) 2 0 .00 - < 0.01 1.00E00 1.00E00 peripheral B cell selection (GO:0002343) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nitric oxide-cGMP mediated signal transduction (GO:0141150) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to triacyl bacterial lipopeptide (GO:0071727) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to diacyl bacterial lipopeptide (GO:0071726) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to triacyl bacterial lipopeptide (GO:0071725) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to diacyl bacterial lipopeptide (GO:0071724) 4 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of arsenic-containing substance (GO:0071722) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001189) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:2001188) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta T cell activation (GO:2001187) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CD8-positive, alpha-beta T cell activation (GO:2001186) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitric oxide-cGMP mediated signal transduction (GO:0141149) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta T cell activation (GO:2001185) 20 0 .01 - < 0.01 1.00E00 1.00E00 B cell selection (GO:0002339) 4 0 .00 - < 0.01 1.00E00 1.00E00 B-1a B cell differentiation (GO:0002337) 2 0 .00 - < 0.01 1.00E00 1.00E00 B-1 B cell lineage commitment (GO:0002336) 1 0 .00 - < 0.01 1.00E00 1.00E00 mature B cell differentiation (GO:0002335) 33 0 .01 - < 0.01 1.00E00 1.00E00 transitional two stage B cell differentiation (GO:0002334) 1 0 .00 - < 0.01 1.00E00 1.00E00 transitional one stage B cell differentiation (GO:0002333) 2 0 .00 - < 0.01 1.00E00 1.00E00 transitional stage B cell differentiation (GO:0002332) 3 0 .00 - < 0.01 1.00E00 1.00E00 pre-B cell allelic exclusion (GO:0002331) 4 0 .00 - < 0.01 1.00E00 1.00E00 locomotor rhythm (GO:0045475) 15 0 .00 - < 0.01 1.00E00 1.00E00 response to ether (GO:0045472) 21 0 .01 - < 0.01 1.00E00 1.00E00 leukotriene transport (GO:0071716) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to ethanol (GO:0045471) 135 0 .04 - < 0.01 1.00E00 1.00E00 icosanoid transport (GO:0071715) 47 0 .01 - < 0.01 1.00E00 1.00E00 basement membrane organization (GO:0071711) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mediator complex assembly (GO:2001178) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mediator complex assembly (GO:2001176) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gene expression, epigenetic (GO:0141137) 57 0 .02 - < 0.01 1.00E00 1.00E00 pre-B cell differentiation (GO:0002329) 5 0 .00 - < 0.01 1.00E00 1.00E00 pro-B cell differentiation (GO:0002328) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ATP biosynthetic process (GO:2001171) 11 0 .00 - < 0.01 1.00E00 1.00E00 immature B cell differentiation (GO:0002327) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ATP biosynthetic process (GO:2001170) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell lineage commitment (GO:0002326) 6 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell activation involved in immune response (GO:0002323) 25 0 .01 - < 0.01 1.00E00 1.00E00 B cell proliferation involved in immune response (GO:0002322) 6 0 .00 - < 0.01 1.00E00 1.00E00 lymphoid progenitor cell differentiation (GO:0002320) 12 0 .00 - < 0.01 1.00E00 1.00E00 membrane assembly (GO:0071709) 61 0 .02 - < 0.01 1.00E00 1.00E00 immunoglobulin heavy chain V-D-J recombination (GO:0071707) 2 0 .00 - < 0.01 1.00E00 1.00E00 nitrogen compound transport (GO:0071705) 1529 0 .45 - < 0.01 1.00E00 1.00E00 galactose catabolic process via UDP-galactose (GO:0033499) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ATP biosynthetic process (GO:2001169) 17 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via lathosterol (GO:0033490) 4 0 .00 - < 0.01 1.00E00 1.00E00 memory B cell differentiation (GO:0002319) 1 0 .00 - < 0.01 1.00E00 1.00E00 myeloid progenitor cell differentiation (GO:0002318) 6 0 .00 - < 0.01 1.00E00 1.00E00 plasma cell differentiation (GO:0002317) 5 0 .00 - < 0.01 1.00E00 1.00E00 intracellular signaling cassette (GO:0141124) 839 0 .24 - < 0.01 1.00E00 1.00E00 follicular B cell differentiation (GO:0002316) 3 0 .00 - < 0.01 1.00E00 1.00E00 marginal zone B cell differentiation (GO:0002315) 9 0 .00 - < 0.01 1.00E00 1.00E00 germinal center B cell differentiation (GO:0002314) 8 0 .00 - < 0.01 1.00E00 1.00E00 mature B cell differentiation involved in immune response (GO:0002313) 27 0 .01 - < 0.01 1.00E00 1.00E00 B cell activation involved in immune response (GO:0002312) 72 0 .02 - < 0.01 1.00E00 1.00E00 cell redox homeostasis (GO:0045454) 41 0 .01 - < 0.01 1.00E00 1.00E00 bone resorption (GO:0045453) 27 0 .01 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via desmosterol (GO:0033489) 4 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process via 24,25-dihydrolanosterol (GO:0033488) 1 0 .00 - < 0.01 1.00E00 1.00E00 intracellular nitric oxide homeostasis (GO:0033484) 4 0 .00 - < 0.01 1.00E00 1.00E00 chromosomal DNA methylation maintenance following DNA replication (GO:0141119) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of renal water transport (GO:2001153) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell proliferation involved in immune response (GO:0002309) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renal water transport (GO:2001151) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dipeptide transmembrane transport (GO:2001150) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, gamma-delta intraepithelial T cell differentiation (GO:0002305) 3 0 .00 - < 0.01 1.00E00 1.00E00 broken chromosome clustering (GO:0141112) 2 0 .00 - < 0.01 1.00E00 1.00E00 gamma-delta intraepithelial T cell differentiation (GO:0002304) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cGAS/STING signaling pathway (GO:0141111) 6 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell differentiation involved in immune response (GO:0002302) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta intraepithelial T cell differentiation (GO:0002300) 1 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell differentiation (GO:0045446) 86 0 .03 - < 0.01 1.00E00 1.00E00 myoblast differentiation (GO:0045445) 41 0 .01 - < 0.01 1.00E00 1.00E00 fat cell differentiation (GO:0045444) 128 0 .04 - < 0.01 1.00E00 1.00E00 S-methylmethionine metabolic process (GO:0033477) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dipeptide transmembrane transport (GO:2001148) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity (GO:2001145) 1 0 .00 - < 0.01 1.00E00 1.00E00 nicotinate transport (GO:2001142) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of RNA biosynthetic process (GO:2001141) 3493 0 1.02 - < 0.01 5.98E-01 1.00E00 positive regulation of phospholipid transport (GO:2001140) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid transport (GO:2001139) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipid transport (GO:2001138) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endocytic recycling (GO:2001137) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endocytic recycling (GO:2001136) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of molecular function (GO:0065009) 1316 0 .38 - < 0.01 1.00E00 1.00E00 regulation of endocytic recycling (GO:2001135) 21 0 .01 - < 0.01 1.00E00 1.00E00 biological regulation (GO:0065007) 12207 5 3.56 + 1.40 4.12E-01 1.00E00 protein-lipid complex assembly (GO:0065005) 27 0 .01 - < 0.01 1.00E00 1.00E00 protein-DNA complex assembly (GO:0065004) 202 0 .06 - < 0.01 1.00E00 1.00E00 protein-containing complex assembly (GO:0065003) 1270 0 .37 - < 0.01 1.00E00 1.00E00 intracellular protein transmembrane transport (GO:0065002) 31 0 .01 - < 0.01 1.00E00 1.00E00 specification of axis polarity (GO:0065001) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nitric oxide biosynthetic process (GO:0045429) 41 0 .01 - < 0.01 1.00E00 1.00E00 nonribosomal peptide biosynthetic process (GO:0019184) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitric oxide biosynthetic process (GO:0045428) 60 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of translational frameshifting (GO:2001125) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational frameshifting (GO:2001124) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to hepatocyte growth factor stimulus (GO:2001114) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to hepatocyte growth factor stimulus (GO:2001113) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to hepatocyte growth factor stimulus (GO:2001112) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lens epithelial cell proliferation (GO:2001111) 2 0 .00 - < 0.01 1.00E00 1.00E00 retina homeostasis (GO:0001895) 59 0 .02 - < 0.01 1.00E00 1.00E00 tissue homeostasis (GO:0001894) 234 0 .07 - < 0.01 1.00E00 1.00E00 maternal placenta development (GO:0001893) 35 0 .01 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic placenta development (GO:0001892) 86 0 .03 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting serotonin receptor signaling pathway (GO:0007198) 10 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting G protein-coupled acetylcholine receptor signaling pathway (GO:0007197) 8 0 .00 - < 0.01 1.00E00 1.00E00 placenta development (GO:0001890) 151 1 .04 + 22.72 4.32E-02 1.00E00 adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway (GO:0007196) 9 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:0007195) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adenylate cyclase activity (GO:0007194) 12 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (GO:0007193) 80 0 .02 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating serotonin receptor signaling pathway (GO:0007192) 5 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) 11 0 .00 - < 0.01 1.00E00 1.00E00 activation of adenylate cyclase activity (GO:0007190) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lens epithelial cell proliferation (GO:2001109) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001108) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Rho guanyl-nucleotide exchange factor activity (GO:2001107) 2 0 .00 - < 0.01 1.00E00 1.00E00 liver development (GO:0001889) 135 0 .04 - < 0.01 1.00E00 1.00E00 selenium compound metabolic process (GO:0001887) 2 0 .00 - < 0.01 1.00E00 1.00E00 membraneless organelle assembly (GO:0140694) 357 0 .10 - < 0.01 1.00E00 1.00E00 endothelial cell morphogenesis (GO:0001886) 13 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell development (GO:0001885) 51 0 .01 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0007189) 170 0 .05 - < 0.01 1.00E00 1.00E00 adenylate cyclase-modulating G protein-coupled receptor signaling pathway (GO:0007188) 255 0 .07 - < 0.01 1.00E00 1.00E00 receptor recycling (GO:0001881) 24 0 .01 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger (GO:0007187) 56 0 .02 - < 0.01 1.00E00 1.00E00 Mullerian duct regression (GO:0001880) 4 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor signaling pathway (GO:0007186) 1256 0 .37 - < 0.01 1.00E00 1.00E00 cell surface receptor protein tyrosine phosphatase signaling pathway (GO:0007185) 6 0 .00 - < 0.01 1.00E00 1.00E00 transforming growth factor beta receptor complex assembly (GO:0007181) 3 0 .00 - < 0.01 1.00E00 1.00E00 detection of yeast (GO:0001879) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to yeast (GO:0001878) 13 0 .00 - < 0.01 1.00E00 1.00E00 transforming growth factor beta receptor signaling pathway (GO:0007179) 99 0 .03 - < 0.01 1.00E00 1.00E00 cell surface receptor protein serine/threonine kinase signaling pathway (GO:0007178) 187 0 .05 - < 0.01 1.00E00 1.00E00 regulation of epidermal growth factor-activated receptor activity (GO:0007176) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) 10 0 .00 - < 0.01 1.00E00 1.00E00 epidermal growth factor catabolic process (GO:0007174) 2 0 .00 - < 0.01 1.00E00 1.00E00 epidermal growth factor receptor signaling pathway (GO:0007173) 102 0 .03 - < 0.01 1.00E00 1.00E00 signal complex assembly (GO:0007172) 8 0 .00 - < 0.01 1.00E00 1.00E00 activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation involved in ureter development (GO:0072199) 3 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation involved in ureter development (GO:0072198) 1 0 .00 - < 0.01 1.00E00 1.00E00 ureter morphogenesis (GO:0072197) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of complement activation, lectin pathway (GO:0001869) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of complement activation, lectin pathway (GO:0001868) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney smooth muscle tissue development (GO:0072194) 2 0 .00 - < 0.01 1.00E00 1.00E00 complement activation, lectin pathway (GO:0001867) 9 0 .00 - < 0.01 1.00E00 1.00E00 ureter smooth muscle cell differentiation (GO:0072193) 2 0 .00 - < 0.01 1.00E00 1.00E00 NK T cell proliferation (GO:0001866) 2 0 .00 - < 0.01 1.00E00 1.00E00 transcription elongation-coupled chromatin remodeling (GO:0140673) 9 0 .00 - < 0.01 1.00E00 1.00E00 NK T cell differentiation (GO:0001865) 5 0 .00 - < 0.01 1.00E00 1.00E00 ureter smooth muscle development (GO:0072191) 2 0 .00 - < 0.01 1.00E00 1.00E00 ureter urothelium development (GO:0072190) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell surface receptor protein tyrosine kinase signaling pathway (GO:0007169) 430 0 .13 - < 0.01 1.00E00 1.00E00 receptor guanylyl cyclase signaling pathway (GO:0007168) 11 0 .00 - < 0.01 1.00E00 1.00E00 enzyme-linked receptor protein signaling pathway (GO:0007167) 626 0 .18 - < 0.01 1.00E00 1.00E00 cell surface receptor signaling pathway (GO:0007166) 2091 0 .61 - < 0.01 1.00E00 1.00E00 signal transduction (GO:0007165) 4895 0 1.43 - < 0.01 3.47E-01 1.00E00 establishment of tissue polarity (GO:0007164) 26 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of cell polarity (GO:0007163) 205 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion (GO:0007162) 292 0 .09 - < 0.01 1.00E00 1.00E00 calcium-independent cell-matrix adhesion (GO:0007161) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell-matrix adhesion (GO:0007160) 137 0 .04 - < 0.01 1.00E00 1.00E00 ureter development (GO:0072189) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oxytocin production (GO:0140668) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric cap morphogenesis (GO:0072186) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oxytocin production (GO:0140667) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric cap development (GO:0072185) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal vesicle progenitor cell differentiation (GO:0072184) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nephron tubule epithelial cell differentiation (GO:0072183) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nephron tubule epithelial cell differentiation (GO:0072182) 12 0 .00 - < 0.01 1.00E00 1.00E00 mesonephric duct formation (GO:0072181) 2 0 .00 - < 0.01 1.00E00 1.00E00 mesonephric duct morphogenesis (GO:0072180) 4 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte cell-cell adhesion (GO:0007159) 57 0 .02 - < 0.01 1.00E00 1.00E00 neuron cell-cell adhesion (GO:0007158) 16 0 .00 - < 0.01 1.00E00 1.00E00 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157) 47 0 .01 - < 0.01 1.00E00 1.00E00 homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156) 168 0 .05 - < 0.01 1.00E00 1.00E00 cell adhesion (GO:0007155) 964 0 .28 - < 0.01 1.00E00 1.00E00 cell communication (GO:0007154) 5272 0 1.54 - < 0.01 3.49E-01 1.00E00 positive regulation of epithelial cell differentiation involved in kidney development (GO:2000698) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell differentiation involved in kidney development (GO:2000697) 4 0 .00 - < 0.01 1.00E00 1.00E00 nephric duct formation (GO:0072179) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell differentiation involved in kidney development (GO:2000696) 16 0 .00 - < 0.01 1.00E00 1.00E00 nephric duct morphogenesis (GO:0072178) 11 0 .00 - < 0.01 1.00E00 1.00E00 mesonephric duct development (GO:0072177) 9 0 .00 - < 0.01 1.00E00 1.00E00 nephric duct development (GO:0072176) 15 0 .00 - < 0.01 1.00E00 1.00E00 epithelial tube formation (GO:0072175) 128 0 .04 - < 0.01 1.00E00 1.00E00 metanephric tubule formation (GO:0072174) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell myoblast differentiation (GO:2000691) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric tubule morphogenesis (GO:0072173) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell myoblast differentiation (GO:2000690) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesonephric tubule formation (GO:0072172) 9 0 .00 - < 0.01 1.00E00 1.00E00 phagolysosome assembly (GO:0001845) 19 0 .01 - < 0.01 1.00E00 1.00E00 mesonephric tubule morphogenesis (GO:0072171) 57 0 .02 - < 0.01 1.00E00 1.00E00 metanephric tubule development (GO:0072170) 21 0 .01 - < 0.01 1.00E00 1.00E00 futile creatine cycle (GO:0140651) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural tube closure (GO:0001843) 86 0 .03 - < 0.01 1.00E00 1.00E00 radial glia-guided pyramidal neuron migration (GO:0140650) 6 0 .00 - < 0.01 1.00E00 1.00E00 neural fold formation (GO:0001842) 7 0 .00 - < 0.01 1.00E00 1.00E00 neural tube formation (GO:0001841) 100 0 .03 - < 0.01 1.00E00 1.00E00 female meiosis II (GO:0007147) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural plate development (GO:0001840) 9 0 .00 - < 0.01 1.00E00 1.00E00 female meiosis I (GO:0007144) 13 0 .00 - < 0.01 1.00E00 1.00E00 female meiotic nuclear division (GO:0007143) 41 0 .01 - < 0.01 1.00E00 1.00E00 male meiosis I (GO:0007141) 28 0 .01 - < 0.01 1.00E00 1.00E00 male meiotic nuclear division (GO:0007140) 56 0 .02 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring assembly actin filament organization (GO:2000689) 4 0 .00 - < 0.01 1.00E00 1.00E00 Rho-activating G protein-coupled receptor signaling pathway (GO:0160221) 5 0 .00 - < 0.01 1.00E00 1.00E00 specification of posterior mesonephric tubule identity (GO:0072169) 1 0 .00 - < 0.01 1.00E00 1.00E00 specification of anterior mesonephric tubule identity (GO:0072168) 1 0 .00 - < 0.01 1.00E00 1.00E00 specification of mesonephric tubule identity (GO:0072167) 1 0 .00 - < 0.01 1.00E00 1.00E00 posterior mesonephric tubule development (GO:0072166) 2 0 .00 - < 0.01 1.00E00 1.00E00 P450-containing electron transport chain (GO:0140647) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to X-ray (GO:2000683) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural plate morphogenesis (GO:0001839) 5 0 .00 - < 0.01 1.00E00 1.00E00 anterior mesonephric tubule development (GO:0072165) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic epithelial tube formation (GO:0001838) 120 0 .03 - < 0.01 1.00E00 1.00E00 mesonephric tubule development (GO:0072164) 89 0 .03 - < 0.01 1.00E00 1.00E00 epithelial to mesenchymal transition (GO:0001837) 85 0 .02 - < 0.01 1.00E00 1.00E00 mesonephric epithelium development (GO:0072163) 89 0 .03 - < 0.01 1.00E00 1.00E00 release of cytochrome c from mitochondria (GO:0001836) 21 0 .01 - < 0.01 1.00E00 1.00E00 male somatic sex determination (GO:0019102) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric mesenchymal cell differentiation (GO:0072162) 5 0 .00 - < 0.01 1.00E00 1.00E00 blastocyst hatching (GO:0001835) 27 0 .01 - < 0.01 1.00E00 1.00E00 female somatic sex determination (GO:0019101) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in kidney development (GO:0072161) 7 0 .00 - < 0.01 1.00E00 1.00E00 trophectodermal cell proliferation (GO:0001834) 3 0 .00 - < 0.01 1.00E00 1.00E00 male germ-line sex determination (GO:0019100) 2 0 .00 - < 0.01 1.00E00 1.00E00 nephron tubule epithelial cell differentiation (GO:0072160) 2 0 .00 - < 0.01 1.00E00 1.00E00 inner cell mass cell proliferation (GO:0001833) 15 0 .00 - < 0.01 1.00E00 1.00E00 blastocyst growth (GO:0001832) 22 0 .01 - < 0.01 1.00E00 1.00E00 trophectodermal cellular morphogenesis (GO:0001831) 2 0 .00 - < 0.01 1.00E00 1.00E00 cloacal septation (GO:0060197) 2 0 .00 - < 0.01 1.00E00 1.00E00 trophectodermal cell fate commitment (GO:0001830) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiosis II (GO:0007135) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipase activity (GO:0060193) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipase activity (GO:0060192) 9 0 .00 - < 0.01 1.00E00 1.00E00 reciprocal meiotic recombination (GO:0007131) 59 0 .02 - < 0.01 1.00E00 1.00E00 synaptonemal complex assembly (GO:0007130) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0160218) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription initiation-coupled chromatin remodeling (GO:0160217) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription regulatory region DNA binding (GO:2000679) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of transcription regulatory region DNA binding (GO:2000678) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription regulatory region DNA binding (GO:2000677) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of type B pancreatic cell apoptotic process (GO:2000676) 3 0 .00 - < 0.01 1.00E00 1.00E00 proximal tubule morphogenesis (GO:0072158) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pyroptotic inflammatory response (GO:0140639) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type B pancreatic cell apoptotic process (GO:2000675) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type B pancreatic cell apoptotic process (GO:2000674) 9 0 .00 - < 0.01 1.00E00 1.00E00 distal tubule morphogenesis (GO:0072156) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of motor neuron apoptotic process (GO:2000673) 2 0 .00 - < 0.01 1.00E00 1.00E00 trophectodermal cell differentiation (GO:0001829) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of motor neuron apoptotic process (GO:2000672) 11 0 .00 - < 0.01 1.00E00 1.00E00 inner cell mass cellular morphogenesis (GO:0001828) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of motor neuron apoptotic process (GO:2000671) 15 0 .00 - < 0.01 1.00E00 1.00E00 inner cell mass cell fate commitment (GO:0001827) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell apoptotic process (GO:2000670) 3 0 .00 - < 0.01 1.00E00 1.00E00 inner cell mass cell differentiation (GO:0001826) 9 0 .00 - < 0.01 1.00E00 1.00E00 CARD8 inflammasome complex assembly (GO:0140633) 1 0 .00 - < 0.01 1.00E00 1.00E00 blastocyst formation (GO:0001825) 46 0 .01 - < 0.01 1.00E00 1.00E00 canonical inflammasome complex assembly (GO:0140632) 9 0 .00 - < 0.01 1.00E00 1.00E00 blastocyst development (GO:0001824) 114 0 .03 - < 0.01 1.00E00 1.00E00 mesonephros development (GO:0001823) 93 0 .03 - < 0.01 1.00E00 1.00E00 homologous chromosome pairing at meiosis (GO:0007129) 53 0 .02 - < 0.01 1.00E00 1.00E00 kidney development (GO:0001822) 308 0 .09 - < 0.01 1.00E00 1.00E00 histamine secretion (GO:0001821) 7 0 .00 - < 0.01 1.00E00 1.00E00 meiosis I (GO:0007127) 126 0 .04 - < 0.01 1.00E00 1.00E00 serotonin secretion (GO:0001820) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle switching (GO:0060184) 4 0 .00 - < 0.01 1.00E00 1.00E00 apelin receptor signaling pathway (GO:0060183) 3 0 .00 - < 0.01 1.00E00 1.00E00 female mating behavior (GO:0060180) 8 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial disulfide relay system (GO:0160203) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell apoptotic process (GO:2000669) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell apoptotic process (GO:2000668) 12 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell fate commitment (GO:0072148) 15 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process via the C-end degron rule pathway (GO:0140627) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytokine production (GO:0001819) 500 0 .15 - < 0.01 1.00E00 1.00E00 negative regulation of cytokine production (GO:0001818) 303 0 .09 - < 0.01 1.00E00 1.00E00 glomerular mesangial cell development (GO:0072144) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-1-mediated signaling pathway (GO:2000661) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytokine production (GO:0001817) 796 0 .23 - < 0.01 1.00E00 1.00E00 mesangial cell development (GO:0072143) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-1-mediated signaling pathway (GO:2000660) 7 0 .00 - < 0.01 1.00E00 1.00E00 cytokine production (GO:0001816) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antibody-dependent cellular cytotoxicity (GO:0001815) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal interstitial fibroblast development (GO:0072141) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antibody-dependent cellular cytotoxicity (GO:0001814) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antibody-dependent cellular cytotoxicity (GO:0001813) 2 0 .00 - < 0.01 1.00E00 1.00E00 male mating behavior (GO:0060179) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type I hypersensitivity (GO:0001812) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of exocyst localization (GO:0060178) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type I hypersensitivity (GO:0001811) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of angiotensin metabolic process (GO:0060177) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type I hypersensitivity (GO:0001810) 2 0 .00 - < 0.01 1.00E00 1.00E00 limb bud formation (GO:0060174) 9 0 .00 - < 0.01 1.00E00 1.00E00 endomitotic cell cycle (GO:0007113) 3 0 .00 - < 0.01 1.00E00 1.00E00 limb development (GO:0060173) 191 0 .06 - < 0.01 1.00E00 1.00E00 male meiosis cytokinesis (GO:0007112) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular anatomical entity morphogenesis (GO:0032989) 131 0 .04 - < 0.01 1.00E00 1.00E00 protein-RNA complex disassembly (GO:0032988) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein-DNA complex disassembly (GO:0032986) 23 0 .01 - < 0.01 1.00E00 1.00E00 protein-containing complex disassembly (GO:0032984) 146 0 .04 - < 0.01 1.00E00 1.00E00 regulation of interleukin-1-mediated signaling pathway (GO:2000659) 10 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex I assembly (GO:0032981) 42 0 .01 - < 0.01 1.00E00 1.00E00 keratinocyte activation (GO:0032980) 2 0 .00 - < 0.01 1.00E00 1.00E00 glomerular parietal epithelial cell differentiation (GO:0072139) 3 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation involved in ureteric bud development (GO:0072138) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to testosterone stimulus (GO:2000655) 1 0 .00 - < 0.01 1.00E00 1.00E00 condensed mesenchymal cell proliferation (GO:0072137) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to testosterone stimulus (GO:2000654) 2 0 .00 - < 0.01 1.00E00 1.00E00 metanephric mesenchymal cell proliferation involved in metanephros development (GO:0072136) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type IV hypersensitivity (GO:0001809) 1 0 .00 - < 0.01 1.00E00 1.00E00 kidney mesenchymal cell proliferation (GO:0072135) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type IV hypersensitivity (GO:0001808) 2 0 .00 - < 0.01 1.00E00 1.00E00 nephrogenic mesenchyme morphogenesis (GO:0072134) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sodium ion transmembrane transporter activity (GO:2000651) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type IV hypersensitivity (GO:0001807) 4 0 .00 - < 0.01 1.00E00 1.00E00 metanephric mesenchyme morphogenesis (GO:0072133) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sodium ion transmembrane transporter activity (GO:2000650) 7 0 .00 - < 0.01 1.00E00 1.00E00 type IV hypersensitivity (GO:0001806) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesenchyme morphogenesis (GO:0072132) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of type III hypersensitivity (GO:0001805) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney mesenchyme morphogenesis (GO:0072131) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal capsule specification (GO:0072130) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type III hypersensitivity (GO:0001803) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adenosine receptor signaling pathway (GO:0060169) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein autoubiquitination (GO:1902499) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenosine receptor signaling pathway (GO:0060168) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein autoubiquitination (GO:1902498) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adenosine receptor signaling pathway (GO:0060167) 4 0 .00 - < 0.01 1.00E00 1.00E00 iron-sulfur cluster transmembrane transport (GO:1902497) 1 0 .00 - < 0.01 1.00E00 1.00E00 olfactory pit development (GO:0060166) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of timing of subpallium neuron differentiation (GO:0060165) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of timing of neuron differentiation (GO:0060164) 3 0 .00 - < 0.01 1.00E00 1.00E00 subpallium neuron fate commitment (GO:0060163) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sperm capacitation (GO:1902492) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine receptor signaling pathway (GO:0060161) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sperm capacitation (GO:1902491) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic centrosome separation (GO:0007100) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopamine receptor signaling pathway (GO:0060160) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sperm capacitation (GO:1902490) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial inner membrane from matrix (GO:0032979) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into membrane from inner side (GO:0032978) 5 0 .00 - < 0.01 1.00E00 1.00E00 release of matrix enzymes from mitochondria (GO:0032976) 1 0 .00 - < 0.01 1.00E00 1.00E00 amino acid transmembrane export from vacuole (GO:0032974) 1 0 .00 - < 0.01 1.00E00 1.00E00 amino acid export across plasma membrane (GO:0032973) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sodium ion transmembrane transporter activity (GO:2000649) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of muscle filament sliding speed (GO:0032972) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of stem cell proliferation (GO:2000648) 47 0 .01 - < 0.01 1.00E00 1.00E00 regulation of muscle filament sliding (GO:0032971) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stem cell proliferation (GO:2000647) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of actin filament-based process (GO:0032970) 390 0 .11 - < 0.01 1.00E00 1.00E00 renal capsule formation (GO:0072129) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor catabolic process (GO:2000646) 8 0 .00 - < 0.01 1.00E00 1.00E00 renal capsule morphogenesis (GO:0072128) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor catabolic process (GO:2000645) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal capsule development (GO:0072127) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor catabolic process (GO:2000644) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glomerular mesangial cell proliferation (GO:0072126) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of early endosome to late endosome transport (GO:2000643) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glomerular mesangial cell proliferation (GO:0072125) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of early endosome to late endosome transport (GO:2000642) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glomerular mesangial cell proliferation (GO:0072124) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of early endosome to late endosome transport (GO:2000641) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of SREBP signaling pathway (GO:2000640) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dopamine receptor signaling pathway (GO:0060159) 11 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating dopamine receptor signaling pathway (GO:0060158) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endopeptidase activity (GO:0052548) 30 0 .01 - < 0.01 1.00E00 1.00E00 urinary bladder development (GO:0060157) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptidase activity (GO:0052547) 49 0 .01 - < 0.01 1.00E00 1.00E00 milk ejection reflex (GO:0060156) 1 0 .00 - < 0.01 1.00E00 1.00E00 platelet dense granule organization (GO:0060155) 25 0 .01 - < 0.01 1.00E00 1.00E00 cytotoxic T cell pyroptotic cell death (GO:1902483) 2 0 .00 - < 0.01 1.00E00 1.00E00 microtubule-based peroxisome localization (GO:0060152) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulatory T cell apoptotic process (GO:1902482) 1 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome localization (GO:0060151) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to mitotic spindle (GO:1902480) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription elongation by RNA polymerase II (GO:0032968) 50 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of collagen biosynthetic process (GO:0032967) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of collagen biosynthetic process (GO:0032966) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collagen biosynthetic process (GO:0032965) 35 0 .01 - < 0.01 1.00E00 1.00E00 collagen biosynthetic process (GO:0032964) 12 0 .00 - < 0.01 1.00E00 1.00E00 collagen metabolic process (GO:0032963) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of SREBP signaling pathway (GO:2000639) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inositol trisphosphate biosynthetic process (GO:0032962) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of SREBP signaling pathway (GO:2000638) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA-mediated gene silencing (GO:2000637) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inositol trisphosphate biosynthetic process (GO:0032960) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of primary miRNA processing (GO:2000636) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of primary miRNA processing (GO:2000635) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of primary miRNA processing (GO:2000634) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pre-miRNA processing (GO:2000633) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of pre-miRNA processing (GO:2000632) 4 0 .00 - < 0.01 1.00E00 1.00E00 pronephros morphogenesis (GO:0072114) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pre-miRNA processing (GO:2000631) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA metabolic process (GO:2000630) 62 0 .02 - < 0.01 1.00E00 1.00E00 podocyte differentiation (GO:0072112) 23 0 .01 - < 0.01 1.00E00 1.00E00 cell proliferation involved in kidney development (GO:0072111) 10 0 .00 - < 0.01 1.00E00 1.00E00 glomerular mesangial cell proliferation (GO:0072110) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of post-transcriptional gene silencing (GO:0060149) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of post-transcriptional gene silencing (GO:0060148) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of post-transcriptional gene silencing (GO:0060147) 31 0 .01 - < 0.01 1.00E00 1.00E00 chloride transmembrane transport (GO:1902476) 113 0 .03 - < 0.01 1.00E00 1.00E00 L-alpha-amino acid transmembrane transport (GO:1902475) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to synapse (GO:1902474) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to synapse (GO:1902473) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of syncytium formation by plasma membrane fusion (GO:0060142) 28 0 .01 - < 0.01 1.00E00 1.00E00 inositol trisphosphate biosynthetic process (GO:0032959) 3 0 .00 - < 0.01 1.00E00 1.00E00 inositol phosphate biosynthetic process (GO:0032958) 13 0 .00 - < 0.01 1.00E00 1.00E00 inositol trisphosphate metabolic process (GO:0032957) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin cytoskeleton organization (GO:0032956) 347 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cytokinetic process (GO:0032954) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA metabolic process (GO:2000629) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of miRNA metabolic process (GO:2000628) 87 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA catabolic process (GO:2000627) 4 0 .00 - < 0.01 1.00E00 1.00E00 glomerular mesangium development (GO:0072109) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA catabolic process (GO:2000626) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0072108) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of miRNA catabolic process (GO:2000625) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ureteric bud formation (GO:0072107) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ureteric bud formation (GO:0072106) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000623) 9 0 .00 - < 0.01 1.00E00 1.00E00 ureteric peristalsis (GO:0072105) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:2000622) 14 0 .00 - < 0.01 1.00E00 1.00E00 glomerular capillary formation (GO:0072104) 6 0 .00 - < 0.01 1.00E00 1.00E00 glomerulus vasculature morphogenesis (GO:0072103) 6 0 .00 - < 0.01 1.00E00 1.00E00 glomerulus morphogenesis (GO:0072102) 9 0 .00 - < 0.01 1.00E00 1.00E00 maternal process involved in parturition (GO:0060137) 5 0 .00 - < 0.01 1.00E00 1.00E00 embryonic process involved in female pregnancy (GO:0060136) 7 0 .00 - < 0.01 1.00E00 1.00E00 maternal process involved in female pregnancy (GO:0060135) 58 0 .02 - < 0.01 1.00E00 1.00E00 prepulse inhibition (GO:0060134) 13 0 .00 - < 0.01 1.00E00 1.00E00 somatotropin secreting cell development (GO:0060133) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell leading edge (GO:1902463) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal stem cell proliferation (GO:1902462) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal stem cell proliferation (GO:1902460) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mononuclear cell proliferation (GO:0032946) 149 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of mononuclear cell proliferation (GO:0032945) 93 0 .03 - < 0.01 1.00E00 1.00E00 regulation of mononuclear cell proliferation (GO:0032944) 247 0 .07 - < 0.01 1.00E00 1.00E00 mononuclear cell proliferation (GO:0032943) 118 0 .03 - < 0.01 1.00E00 1.00E00 secretion by tissue (GO:0032941) 30 0 .01 - < 0.01 1.00E00 1.00E00 secretion by cell (GO:0032940) 431 0 .13 - < 0.01 1.00E00 1.00E00 regulation of thyroid-stimulating hormone secretion (GO:2000612) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of thyroid hormone generation (GO:2000611) 5 0 .00 - < 0.01 1.00E00 1.00E00 thyroid-stimulating hormone-secreting cell differentiation (GO:0060129) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of stem cell population maintenance (GO:1902459) 49 0 .01 - < 0.01 1.00E00 1.00E00 corticotropin hormone secreting cell differentiation (GO:0060128) 3 0 .00 - < 0.01 1.00E00 1.00E00 prolactin secreting cell differentiation (GO:0060127) 2 0 .00 - < 0.01 1.00E00 1.00E00 somatotropin secreting cell differentiation (GO:0060126) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of growth hormone secretion (GO:0060125) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stem cell population maintenance (GO:1902455) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of growth hormone secretion (GO:0060124) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of growth hormone secretion (GO:0060123) 11 0 .00 - < 0.01 1.00E00 1.00E00 inner ear receptor cell stereocilium organization (GO:0060122) 39 0 .01 - < 0.01 1.00E00 1.00E00 bile acid biosynthetic process (GO:0006699) 27 0 .01 - < 0.01 1.00E00 1.00E00 vestibular receptor cell stereocilium organization (GO:0060121) 1 0 .00 - < 0.01 1.00E00 1.00E00 inner ear receptor cell fate commitment (GO:0060120) 4 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol biosynthetic process (GO:0006695) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of translation in response to oxidative stress (GO:0032938) 1 0 .00 - < 0.01 1.00E00 1.00E00 prostaglandin metabolic process (GO:0006693) 39 0 .01 - < 0.01 1.00E00 1.00E00 prostanoid metabolic process (GO:0006692) 41 0 .01 - < 0.01 1.00E00 1.00E00 leukotriene metabolic process (GO:0006691) 34 0 .01 - < 0.01 1.00E00 1.00E00 icosanoid metabolic process (GO:0006690) 117 0 .03 - < 0.01 1.00E00 1.00E00 SREBP signaling pathway (GO:0032933) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thyroid hormone generation (GO:2000609) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in mesonephros development (GO:2000607) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of superoxide anion generation (GO:0032930) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in mesonephros development (GO:2000606) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Arp2/3 complex-mediated actin nucleation (GO:2000601) 8 0 .00 - < 0.01 1.00E00 1.00E00 inner ear receptor cell development (GO:0060119) 52 0 .02 - < 0.01 1.00E00 1.00E00 vestibular receptor cell development (GO:0060118) 2 0 .00 - < 0.01 1.00E00 1.00E00 auditory receptor cell development (GO:0060117) 29 0 .01 - < 0.01 1.00E00 1.00E00 vestibular receptor cell morphogenesis (GO:0060116) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death (GO:1902445) 3 0 .00 - < 0.01 1.00E00 1.00E00 vestibular receptor cell differentiation (GO:0060114) 2 0 .00 - < 0.01 1.00E00 1.00E00 inner ear receptor cell differentiation (GO:0060113) 67 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of ripoptosome assembly involved in necroptotic process (GO:1902443) 1 0 .00 - < 0.01 1.00E00 1.00E00 generation of ovulation cycle rhythm (GO:0060112) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ripoptosome assembly involved in necroptotic process (GO:1902442) 1 0 .00 - < 0.01 1.00E00 1.00E00 ganglioside catabolic process (GO:0006689) 8 0 .00 - < 0.01 1.00E00 1.00E00 glycosphingolipid biosynthetic process (GO:0006688) 39 0 .01 - < 0.01 1.00E00 1.00E00 glycosphingolipid metabolic process (GO:0006687) 64 0 .02 - < 0.01 1.00E00 1.00E00 sphingomyelin biosynthetic process (GO:0006686) 11 0 .00 - < 0.01 1.00E00 1.00E00 sphingomyelin catabolic process (GO:0006685) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of superoxide anion generation (GO:0032929) 2 0 .00 - < 0.01 1.00E00 1.00E00 sphingomyelin metabolic process (GO:0006684) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of superoxide anion generation (GO:0032928) 23 0 .01 - < 0.01 1.00E00 1.00E00 galactosylceramide catabolic process (GO:0006683) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of activin receptor signaling pathway (GO:0032927) 6 0 .00 - < 0.01 1.00E00 1.00E00 galactosylceramide biosynthetic process (GO:0006682) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of activin receptor signaling pathway (GO:0032926) 17 0 .00 - < 0.01 1.00E00 1.00E00 galactosylceramide metabolic process (GO:0006681) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of activin receptor signaling pathway (GO:0032925) 26 0 .01 - < 0.01 1.00E00 1.00E00 glucosylceramide catabolic process (GO:0006680) 3 0 .00 - < 0.01 1.00E00 1.00E00 activin receptor signaling pathway (GO:0032924) 34 0 .01 - < 0.01 1.00E00 1.00E00 circadian regulation of gene expression (GO:0032922) 67 0 .02 - < 0.01 1.00E00 1.00E00 putrescine acetylation (GO:0032920) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of male mating behavior (GO:1902437) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of male mating behavior (GO:1902435) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucosylceramide biosynthetic process (GO:0006679) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phagocytosis, engulfment (GO:0060101) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucosylceramide metabolic process (GO:0006678) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phagocytosis, engulfment (GO:0060100) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid-beta formation (GO:1902430) 18 0 .01 - < 0.01 1.00E00 1.00E00 glycosylceramide metabolic process (GO:0006677) 15 0 .00 - < 0.01 1.00E00 1.00E00 spermine acetylation (GO:0032919) 1 0 .00 - < 0.01 1.00E00 1.00E00 spermidine acetylation (GO:0032918) 3 0 .00 - < 0.01 1.00E00 1.00E00 polyamine acetylation (GO:0032917) 3 0 .00 - < 0.01 1.00E00 1.00E00 ceramide metabolic process (GO:0006672) 99 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta3 production (GO:0032916) 1 0 .00 - < 0.01 1.00E00 1.00E00 phytosphingosine metabolic process (GO:0006671) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta2 production (GO:0032915) 3 0 .00 - < 0.01 1.00E00 1.00E00 sphingosine metabolic process (GO:0006670) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta1 production (GO:0032914) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta3 production (GO:0032913) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta2 production (GO:0032912) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta1 production (GO:0032911) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta3 production (GO:0032910) 2 0 .00 - < 0.01 1.00E00 1.00E00 olfactory placode morphogenesis (GO:0071699) 3 0 .00 - < 0.01 1.00E00 1.00E00 olfactory placode development (GO:0071698) 3 0 .00 - < 0.01 1.00E00 1.00E00 ectodermal placode morphogenesis (GO:0071697) 12 0 .00 - < 0.01 1.00E00 1.00E00 ectodermal placode development (GO:0071696) 14 0 .00 - < 0.01 1.00E00 1.00E00 anatomical structure maturation (GO:0071695) 242 0 .07 - < 0.01 1.00E00 1.00E00 maintenance of protein location in extracellular region (GO:0071694) 7 0 .00 - < 0.01 1.00E00 1.00E00 deactivation of mitotic spindle assembly checkpoint (GO:1902426) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein transport within extracellular region (GO:0071693) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of attachment of mitotic spindle microtubules to kinetochore (GO:1902425) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to extracellular region (GO:0071692) 134 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of attachment of mitotic spindle microtubules to kinetochore (GO:1902424) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle thin filament assembly (GO:0071691) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of attachment of mitotic spindle microtubules to kinetochore (GO:1902423) 10 0 .00 - < 0.01 1.00E00 1.00E00 sphinganine-1-phosphate biosynthetic process (GO:0006669) 1 0 .00 - < 0.01 1.00E00 1.00E00 sphinganine-1-phosphate metabolic process (GO:0006668) 2 0 .00 - < 0.01 1.00E00 1.00E00 sphinganine metabolic process (GO:0006667) 3 0 .00 - < 0.01 1.00E00 1.00E00 3-keto-sphinganine metabolic process (GO:0006666) 1 0 .00 - < 0.01 1.00E00 1.00E00 sphingolipid metabolic process (GO:0006665) 163 0 .05 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta2 production (GO:0032909) 8 0 .00 - < 0.01 1.00E00 1.00E00 glycolipid metabolic process (GO:0006664) 107 0 .03 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta1 production (GO:0032908) 12 0 .00 - < 0.01 1.00E00 1.00E00 platelet activating factor biosynthetic process (GO:0006663) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycerol ether metabolic process (GO:0006662) 22 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylinositol biosynthetic process (GO:0006661) 115 0 .03 - < 0.01 1.00E00 1.00E00 transforming growth factor beta1 production (GO:0032905) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylserine catabolic process (GO:0006660) 4 0 .00 - < 0.01 1.00E00 1.00E00 nerve growth factor production (GO:0032902) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurotrophin production (GO:0032901) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neurotrophin production (GO:0032900) 1 0 .00 - < 0.01 1.00E00 1.00E00 TORC2 signaling (GO:0038203) 9 0 .00 - < 0.01 1.00E00 1.00E00 TORC1 signaling (GO:0038202) 20 0 .01 - < 0.01 1.00E00 1.00E00 striated muscle myosin thick filament assembly (GO:0071688) 3 0 .00 - < 0.01 1.00E00 1.00E00 organism emergence from protective structure (GO:0071684) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA binding (GO:1902416) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA binding (GO:1902415) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell junction (GO:1902414) 88 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to indole-3-methanol (GO:0071681) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to indole-3-methanol (GO:0071680) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cytokinesis (GO:1902412) 16 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylserine biosynthetic process (GO:0006659) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylserine metabolic process (GO:0006658) 21 0 .01 - < 0.01 1.00E00 1.00E00 mitotic cytokinetic process (GO:1902410) 31 0 .01 - < 0.01 1.00E00 1.00E00 CDP-choline pathway (GO:0006657) 7 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylcholine biosynthetic process (GO:0006656) 24 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol biosynthetic process (GO:0006655) 6 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidic acid biosynthetic process (GO:0006654) 32 0 .01 - < 0.01 1.00E00 1.00E00 diacylglycerol biosynthetic process (GO:0006651) 7 0 .00 - < 0.01 1.00E00 1.00E00 alpha-beta intraepithelial T cell differentiation (GO:0002299) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycerophospholipid metabolic process (GO:0006650) 282 0 .08 - < 0.01 1.00E00 1.00E00 T-helper 1 cell lineage commitment (GO:0002296) 4 0 .00 - < 0.01 1.00E00 1.00E00 T-helper cell lineage commitment (GO:0002295) 15 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294) 49 0 .01 - < 0.01 1.00E00 1.00E00 alpha-beta T cell differentiation involved in immune response (GO:0002293) 50 0 .01 - < 0.01 1.00E00 1.00E00 T cell differentiation involved in immune response (GO:0002292) 54 0 .02 - < 0.01 1.00E00 1.00E00 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell (GO:0002291) 8 0 .00 - < 0.01 1.00E00 1.00E00 commissural neuron axon guidance (GO:0071679) 14 0 .00 - < 0.01 1.00E00 1.00E00 olfactory bulb axon guidance (GO:0071678) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mononuclear cell migration (GO:0071677) 97 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of mononuclear cell migration (GO:0071676) 32 1 .01 + > 100 9.29E-03 1.00E00 regulation of mononuclear cell migration (GO:0071675) 144 1 .04 + 23.82 4.13E-02 1.00E00 assembly of actomyosin apparatus involved in mitotic cytokinesis (GO:1902407) 3 0 .00 - < 0.01 1.00E00 1.00E00 mononuclear cell migration (GO:0071674) 113 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell chemotaxis (GO:0071673) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell chemotaxis (GO:0071672) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell chemotaxis (GO:0071671) 6 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle cell chemotaxis (GO:0071670) 2 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid transfer to membrane (GO:0006649) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylethanolamine biosynthetic process (GO:0006646) 9 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid metabolic process (GO:0006644) 356 0 .10 - < 0.01 1.00E00 1.00E00 membrane lipid metabolic process (GO:0006643) 209 0 .06 - < 0.01 1.00E00 1.00E00 triglyceride mobilization (GO:0006642) 4 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride metabolic process (GO:0006641) 73 0 .02 - < 0.01 1.00E00 1.00E00 monoacylglycerol biosynthetic process (GO:0006640) 9 0 .00 - < 0.01 1.00E00 1.00E00 alpha-beta T cell activation involved in immune response (GO:0002287) 50 0 .01 - < 0.01 1.00E00 1.00E00 T cell activation involved in immune response (GO:0002286) 91 0 .03 - < 0.01 1.00E00 1.00E00 lymphocyte activation involved in immune response (GO:0002285) 146 0 .04 - < 0.01 1.00E00 1.00E00 transforming growth factor beta receptor superfamily signaling pathway (GO:0141091) 175 0 .05 - < 0.01 1.00E00 1.00E00 neutrophil activation involved in immune response (GO:0002283) 14 0 .00 - < 0.01 1.00E00 1.00E00 microglial cell activation involved in immune response (GO:0002282) 5 0 .00 - < 0.01 1.00E00 1.00E00 macrophage activation involved in immune response (GO:0002281) 19 0 .01 - < 0.01 1.00E00 1.00E00 monocyte activation involved in immune response (GO:0002280) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of granzyme B production (GO:0071663) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granzyme B production (GO:0071661) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of IP-10 production (GO:0071660) 1 0 .00 - < 0.01 1.00E00 1.00E00 acylglycerol metabolic process (GO:0006639) 100 0 .03 - < 0.01 1.00E00 1.00E00 neutral lipid metabolic process (GO:0006638) 101 0 .03 - < 0.01 1.00E00 1.00E00 acyl-CoA metabolic process (GO:0006637) 92 0 .03 - < 0.01 1.00E00 1.00E00 unsaturated fatty acid biosynthetic process (GO:0006636) 40 0 .01 - < 0.01 1.00E00 1.00E00 fatty acid beta-oxidation (GO:0006635) 58 0 .02 - < 0.01 1.00E00 1.00E00 fatty acid biosynthetic process (GO:0006633) 121 0 .04 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by tRNA modification (GO:1990983) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid metabolic process (GO:0006631) 328 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of inflammasome-mediated signaling pathway (GO:0141087) 27 0 .01 - < 0.01 1.00E00 1.00E00 mast cell activation involved in immune response (GO:0002279) 30 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of inflammasome-mediated signaling pathway (GO:0141086) 20 0 .01 - < 0.01 1.00E00 1.00E00 eosinophil activation involved in immune response (GO:0002278) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inflammasome-mediated signaling pathway (GO:0141085) 49 0 .01 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell activation involved in immune response (GO:0002277) 3 0 .00 - < 0.01 1.00E00 1.00E00 inflammasome-mediated signaling pathway (GO:0141084) 10 0 .00 - < 0.01 1.00E00 1.00E00 basophil activation involved in immune response (GO:0002276) 2 0 .00 - < 0.01 1.00E00 1.00E00 myeloid cell activation involved in immune response (GO:0002275) 67 0 .02 - < 0.01 1.00E00 1.00E00 myeloid leukocyte activation (GO:0002274) 155 0 .05 - < 0.01 1.00E00 1.00E00 plasmacytoid dendritic cell differentiation (GO:0002273) 2 0 .00 - < 0.01 1.00E00 1.00E00 plasmacytoid dendritic cell activation (GO:0002270) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of IP-10 production (GO:0071659) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of IP-10 production (GO:0071658) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of granulocyte colony-stimulating factor production (GO:0071657) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte colony-stimulating factor production (GO:0071656) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granulocyte colony-stimulating factor production (GO:0071655) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 1 production (GO:0071654) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 1 production (GO:0071652) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 5 production (GO:0071651) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine (C-C motif) ligand 5 production (GO:0071650) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein processing involved in protein targeting to mitochondrion (GO:0006627) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to mitochondrion (GO:0006626) 64 0 .02 - < 0.01 1.00E00 1.00E00 protein targeting to peroxisome (GO:0006625) 10 0 .00 - < 0.01 1.00E00 1.00E00 vacuolar protein processing (GO:0006624) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to vacuole (GO:0006623) 47 0 .01 - < 0.01 1.00E00 1.00E00 protein targeting to lysosome (GO:0006622) 32 0 .01 - < 0.01 1.00E00 1.00E00 protein retention in ER lumen (GO:0006621) 8 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte activation involved in inflammatory response (GO:0002269) 34 0 .01 - < 0.01 1.00E00 1.00E00 post-translational protein targeting to endoplasmic reticulum membrane (GO:0006620) 15 0 .00 - < 0.01 1.00E00 1.00E00 follicular dendritic cell differentiation (GO:0002268) 2 0 .00 - < 0.01 1.00E00 1.00E00 follicular dendritic cell activation (GO:0002266) 3 0 .00 - < 0.01 1.00E00 1.00E00 astrocyte activation involved in immune response (GO:0002265) 4 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell activation involved in immune response (GO:0002264) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell activation involved in immune response (GO:0002263) 214 0 .06 - < 0.01 1.00E00 1.00E00 myeloid cell homeostasis (GO:0002262) 145 0 .04 - < 0.01 1.00E00 1.00E00 lymphocyte homeostasis (GO:0002260) 73 0 .02 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 5 production (GO:0071649) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine (C-C motif) ligand 4 production (GO:0071644) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 4 production (GO:0071643) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage inflammatory protein 1 alpha production (GO:0071642) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage inflammatory protein 1 alpha production (GO:0071641) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage inflammatory protein 1 alpha production (GO:0071640) 6 0 .00 - < 0.01 1.00E00 1.00E00 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition (GO:0006617) 4 0 .00 - < 0.01 1.00E00 1.00E00 SRP-dependent cotranslational protein targeting to membrane, translocation (GO:0006616) 8 0 .00 - < 0.01 1.00E00 1.00E00 ATP generation from poly-ADP-D-ribose (GO:1990966) 4 0 .00 - < 0.01 1.00E00 1.00E00 SRP-dependent cotranslational protein targeting to membrane (GO:0006614) 17 0 .00 - < 0.01 1.00E00 1.00E00 cotranslational protein targeting to membrane (GO:0006613) 22 0 .01 - < 0.01 1.00E00 1.00E00 protein targeting to membrane (GO:0006612) 86 0 .03 - < 0.01 1.00E00 1.00E00 autosome genomic imprinting (GO:0141068) 6 0 .00 - < 0.01 1.00E00 1.00E00 establishment of blood-retinal barrier (GO:1990963) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein export from nucleus (GO:0006611) 32 0 .01 - < 0.01 1.00E00 1.00E00 intracellular nitrogen homeostasis (GO:0141067) 1 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic transport across blood-brain barrier (GO:1990962) 6 0 .00 - < 0.01 1.00E00 1.00E00 ribosomal protein import into nucleus (GO:0006610) 4 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic detoxification by transmembrane export across the plasma membrane (GO:1990961) 11 0 .00 - < 0.01 1.00E00 1.00E00 maternal mRNA clearance (GO:0141065) 1 0 .00 - < 0.01 1.00E00 1.00E00 basophil homeostasis (GO:1990960) 1 0 .00 - < 0.01 1.00E00 1.00E00 zygotic genome activation (GO:0141064) 1 0 .00 - < 0.01 1.00E00 1.00E00 kinin cascade (GO:0002254) 3 0 .00 - < 0.01 1.00E00 1.00E00 disruption of cell in another organism (GO:0141061) 114 0 .03 - < 0.01 1.00E00 1.00E00 activation of immune response (GO:0002253) 399 0 .12 - < 0.01 1.00E00 1.00E00 disruption of anatomical structure in another organism (GO:0141060) 118 0 .03 - < 0.01 1.00E00 1.00E00 immune effector process (GO:0002252) 493 0 .14 - < 0.01 1.00E00 1.00E00 organ or tissue specific immune response (GO:0002251) 37 0 .01 - < 0.01 1.00E00 1.00E00 adaptive immune response (GO:0002250) 680 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte chemotactic protein-1 production (GO:0071639) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte chemotactic protein-1 production (GO:0071638) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of monocyte chemotactic protein-1 production (GO:0071637) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta production (GO:0071636) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta production (GO:0071635) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta production (GO:0071634) 32 0 .01 - < 0.01 1.00E00 1.00E00 nuclear protein quality control by the ubiquitin-proteasome system (GO:0071630) 4 0 .00 - < 0.01 1.00E00 1.00E00 homogentisate metabolic process (GO:1901999) 1 0 .00 - < 0.01 1.00E00 1.00E00 eosinophil homeostasis (GO:1990959) 3 0 .00 - < 0.01 1.00E00 1.00E00 NLS-bearing protein import into nucleus (GO:0006607) 19 0 .01 - < 0.01 1.00E00 1.00E00 protein import into nucleus (GO:0006606) 117 0 .03 - < 0.01 1.00E00 1.00E00 protein targeting (GO:0006605) 255 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of meiotic cell cycle phase transition (GO:1901995) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic cell cycle phase transition (GO:1901994) 7 0 .00 - < 0.01 1.00E00 1.00E00 phosphocreatine metabolic process (GO:0006603) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of meiotic cell cycle phase transition (GO:1901993) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle phase transition (GO:1901992) 93 0 .03 - < 0.01 1.00E00 1.00E00 intramanchette transport (GO:1990953) 2 0 .00 - < 0.01 1.00E00 1.00E00 creatine biosynthetic process (GO:0006601) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic cell cycle phase transition (GO:1901991) 158 0 .05 - < 0.01 1.00E00 1.00E00 lymphocyte anergy (GO:0002249) 4 0 .00 - < 0.01 1.00E00 1.00E00 creatine metabolic process (GO:0006600) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle phase transition (GO:1901990) 330 0 .10 - < 0.01 1.00E00 1.00E00 connective tissue replacement involved in inflammatory response wound healing (GO:0002248) 5 0 .00 - < 0.01 1.00E00 1.00E00 wound healing involved in inflammatory response (GO:0002246) 7 0 .00 - < 0.01 1.00E00 1.00E00 hematopoietic progenitor cell differentiation (GO:0002244) 101 0 .03 - < 0.01 1.00E00 1.00E00 cytoplasm protein quality control by the ubiquitin-proteasome system (GO:0071629) 3 0 .00 - < 0.01 1.00E00 1.00E00 mastication (GO:0071626) 4 0 .00 - < 0.01 1.00E00 1.00E00 vocalization behavior (GO:0071625) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of granulocyte chemotaxis (GO:0071624) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte chemotaxis (GO:0071623) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granulocyte chemotaxis (GO:0071622) 54 0 .02 - < 0.01 1.00E00 1.00E00 granulocyte chemotaxis (GO:0071621) 76 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle phase transition (GO:1901989) 114 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle phase transition (GO:1901988) 220 0 .06 - < 0.01 1.00E00 1.00E00 metaphase/anaphase transition of meiosis I (GO:1990949) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell cycle phase transition (GO:1901987) 436 0 .13 - < 0.01 1.00E00 1.00E00 response to ketamine (GO:1901986) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein acetylation (GO:1901985) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein acetylation (GO:1901984) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein acetylation (GO:1901983) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to molecule of fungal origin (GO:0002238) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to molecule of bacterial origin (GO:0002237) 343 0 .10 - < 0.01 1.00E00 1.00E00 leukocyte chemotaxis involved in inflammatory response (GO:0002232) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of defense response to virus by host (GO:0002230) 33 0 .01 - < 0.01 1.00E00 1.00E00 acyl-CoA biosynthetic process (GO:0071616) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of inward rectifier potassium channel activity (GO:1901979) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle checkpoint (GO:1901978) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle checkpoint (GO:1901977) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell cycle checkpoint (GO:1901976) 49 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric ureteric bud development (GO:2001076) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric ureteric bud development (GO:2001074) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic sister chromatid separation (GO:1901970) 21 0 .01 - < 0.01 1.00E00 1.00E00 natural killer cell mediated immunity (GO:0002228) 44 0 .01 - < 0.01 1.00E00 1.00E00 innate immune response in mucosa (GO:0002227) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial peptide production (GO:0002225) 7 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor signaling pathway (GO:0002224) 47 0 .01 - < 0.01 1.00E00 1.00E00 stimulatory C-type lectin receptor signaling pathway (GO:0002223) 22 0 .01 - < 0.01 1.00E00 1.00E00 stimulatory killer cell immunoglobulin-like receptor signaling pathway (GO:0002222) 2 0 .00 - < 0.01 1.00E00 1.00E00 pattern recognition receptor signaling pathway (GO:0002221) 132 0 .04 - < 0.01 1.00E00 1.00E00 innate immune response activating cell surface receptor signaling pathway (GO:0002220) 65 0 .02 - < 0.01 1.00E00 1.00E00 transforming growth factor beta production (GO:0071604) 5 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell-cell adhesion (GO:0071603) 4 0 .00 - < 0.01 1.00E00 1.00E00 phytosphingosine biosynthetic process (GO:0071602) 1 0 .00 - < 0.01 1.00E00 1.00E00 beta-alanine biosynthetic process via 3-ureidopropionate (GO:0033396) 1 0 .00 - < 0.01 1.00E00 1.00E00 otic vesicle morphogenesis (GO:0071600) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to amino acid starvation (GO:1990928) 56 0 .02 - < 0.01 1.00E00 1.00E00 calcium ion regulated lysosome exocytosis (GO:1990927) 3 0 .00 - < 0.01 1.00E00 1.00E00 short-term synaptic potentiation (GO:1990926) 3 0 .00 - < 0.01 1.00E00 1.00E00 S-adenosyl-L-methionine transmembrane transport (GO:1901962) 1 0 .00 - < 0.01 1.00E00 1.00E00 activation of innate immune response (GO:0002218) 176 0 .05 - < 0.01 1.00E00 1.00E00 defense response to nematode (GO:0002215) 3 0 .00 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from arginine, via agmatine (GO:0033389) 1 0 .00 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from arginine (GO:0033388) 4 0 .00 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process from arginine, via ornithine (GO:0033387) 3 0 .00 - < 0.01 1.00E00 1.00E00 geranylgeranyl diphosphate biosynthetic process (GO:0033386) 1 0 .00 - < 0.01 1.00E00 1.00E00 geranylgeranyl diphosphate metabolic process (GO:0033385) 2 0 .00 - < 0.01 1.00E00 1.00E00 geranyl diphosphate biosynthetic process (GO:0033384) 2 0 .00 - < 0.01 1.00E00 1.00E00 geranyl diphosphate metabolic process (GO:0033383) 3 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair involved in meiotic recombination (GO:1990918) 11 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of granzyme B location in T cell secretory granule (GO:0033382) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde dense core granule transport (GO:1901956) 1 0 .00 - < 0.01 1.00E00 1.00E00 reactive nitrogen species metabolic process (GO:2001057) 34 0 .01 - < 0.01 1.00E00 1.00E00 granzyme B localization to T cell secretory granule (GO:0033380) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retrograde dense core granule transport (GO:1901954) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde dense core granule transport (GO:1901953) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal cell apoptotic process (GO:2001055) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process (GO:2001054) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anterograde dense core granule transport (GO:1901951) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process (GO:2001053) 14 0 .00 - < 0.01 1.00E00 1.00E00 behavioral defense response (GO:0002209) 35 0 .01 - < 0.01 1.00E00 1.00E00 dense core granule transport (GO:1901950) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to psychosocial stress (GO:1990911) 5 0 .00 - < 0.01 1.00E00 1.00E00 somatic diversification of immunoglobulins involved in immune response (GO:0002208) 29 0 .01 - < 0.01 1.00E00 1.00E00 response to hypobaric hypoxia (GO:1990910) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tendon cell differentiation (GO:2001051) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribosome hibernation (GO:0141014) 4 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleotide import into lysosome (GO:0141013) 1 0 .00 - < 0.01 1.00E00 1.00E00 somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) 25 0 .01 - < 0.01 1.00E00 1.00E00 somatic diversification of immune receptors (GO:0002200) 54 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of MHC class II biosynthetic process (GO:0045348) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of MHC class II biosynthetic process (GO:0045347) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of MHC class II biosynthetic process (GO:0045346) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of MHC class I biosynthetic process (GO:0045345) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of MHC class I biosynthetic process (GO:0045344) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of MHC class I biosynthetic process (GO:0045343) 8 0 .00 - < 0.01 1.00E00 1.00E00 MHC class II biosynthetic process (GO:0045342) 2 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protease location in T cell secretory granule (GO:0033379) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein location in T cell secretory granule (GO:0033377) 1 0 .00 - < 0.01 1.00E00 1.00E00 protease localization to T cell secretory granule (GO:0033375) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to T cell secretory granule (GO:0033374) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protease location in mast cell secretory granule (GO:0033373) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tendon cell differentiation (GO:2001049) 2 0 .00 - < 0.01 1.00E00 1.00E00 T cell secretory granule organization (GO:0033371) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein location in mast cell secretory granule (GO:0033370) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of integrin-mediated signaling pathway (GO:2001046) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of integrin-mediated signaling pathway (GO:2001045) 3 0 .00 - < 0.01 1.00E00 1.00E00 transposable element silencing by mRNA destabilization (GO:0141008) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of integrin-mediated signaling pathway (GO:2001044) 20 0 .01 - < 0.01 1.00E00 1.00E00 transposable element silencing by piRNA-mediated heterochromatin formation (GO:0141006) 5 0 .00 - < 0.01 1.00E00 1.00E00 transposable element silencing by heterochromatin formation (GO:0141005) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to drug (GO:2001040) 1 0 .00 - < 0.01 1.00E00 1.00E00 reproductive behavior (GO:0019098) 42 0 .01 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate catabolic process (GO:0045339) 1 0 .00 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate metabolic process (GO:0045338) 6 0 .00 - < 0.01 1.00E00 1.00E00 farnesyl diphosphate biosynthetic process (GO:0045337) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular respiration (GO:0045333) 188 0 .05 - < 0.01 1.00E00 1.00E00 phospholipid translocation (GO:0045332) 53 0 .02 - < 0.01 1.00E00 1.00E00 protease localization to mast cell secretory granule (GO:0033368) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to mast cell secretory granule (GO:0033367) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to secretory granule (GO:0033366) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to organelle (GO:0033365) 762 0 .22 - < 0.01 1.00E00 1.00E00 mast cell secretory granule organization (GO:0033364) 2 0 .00 - < 0.01 1.00E00 1.00E00 secretory granule organization (GO:0033363) 73 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cellular response to drug (GO:2001038) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tongue muscle cell differentiation (GO:2001037) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tongue muscle cell differentiation (GO:2001035) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of double-strand break repair via nonhomologous end joining (GO:2001034) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of double-strand break repair via nonhomologous end joining (GO:2001033) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of double-strand break repair via nonhomologous end joining (GO:2001032) 29 0 .01 - < 0.01 1.00E00 1.00E00 late viral transcription (GO:0019086) 4 0 .00 - < 0.01 1.00E00 1.00E00 early viral transcription (GO:0019085) 2 0 .00 - < 0.01 1.00E00 1.00E00 carnitine biosynthetic process (GO:0045329) 5 0 .00 - < 0.01 1.00E00 1.00E00 viral transcription (GO:0019083) 6 0 .00 - < 0.01 1.00E00 1.00E00 viral protein processing (GO:0019082) 31 0 .01 - < 0.01 1.00E00 1.00E00 viral translation (GO:0019081) 38 0 .01 - < 0.01 1.00E00 1.00E00 viral gene expression (GO:0019080) 74 0 .02 - < 0.01 1.00E00 1.00E00 late endosome to vacuole transport (GO:0045324) 38 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte activation (GO:0045321) 624 0 .18 - < 0.01 1.00E00 1.00E00 S-adenosylmethionine cycle (GO:0033353) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis (GO:2001028) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell chemotaxis (GO:2001027) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell chemotaxis (GO:2001026) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of response to drug (GO:2001025) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase C/protein kinase C signal transduction (GO:0160195) 3 0 .00 - < 0.01 1.00E00 1.00E00 stereocilium bundle organization (GO:0160194) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to drug (GO:2001023) 4 0 .00 - < 0.01 1.00E00 1.00E00 autophagosome-dependent secretion (GO:0160192) 1 0 .00 - < 0.01 1.00E00 1.00E00 viral genome replication (GO:0019079) 19 0 .01 - < 0.01 1.00E00 1.00E00 viral release from host cell (GO:0019076) 29 0 .01 - < 0.01 1.00E00 1.00E00 virus maturation (GO:0019075) 2 0 .00 - < 0.01 1.00E00 1.00E00 viral RNA genome packaging (GO:0019074) 2 0 .00 - < 0.01 1.00E00 1.00E00 viral genome packaging (GO:0019072) 2 0 .00 - < 0.01 1.00E00 1.00E00 asparagine catabolic process via L-aspartate (GO:0033345) 1 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol efflux (GO:0033344) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde axon cargo transport (GO:2001019) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of collagen binding (GO:0033342) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retrograde axon cargo transport (GO:2001017) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle cell differentiation (GO:2001016) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle cell differentiation (GO:2001015) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle cell differentiation (GO:2001014) 21 0 .01 - < 0.01 1.00E00 1.00E00 paracellular transport (GO:0160184) 7 0 .00 - < 0.01 1.00E00 1.00E00 adenosine 5'-(hexahydrogen pentaphosphate) catabolic process (GO:1901911) 5 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in renal tubule morphogenesis (GO:2001013) 5 0 .00 - < 0.01 1.00E00 1.00E00 adenosine 5'-(hexahydrogen pentaphosphate) metabolic process (GO:1901910) 5 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in renal system development (GO:2001012) 7 0 .00 - < 0.01 1.00E00 1.00E00 virion assembly (GO:0019068) 34 0 .01 - < 0.01 1.00E00 1.00E00 receptor-mediated endocytosis of virus by host cell (GO:0019065) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type IIa hypersensitivity (GO:0001798) 3 0 .00 - < 0.01 1.00E00 1.00E00 fusion of virus membrane with host plasma membrane (GO:0019064) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type IIa hypersensitivity (GO:0001797) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type IIa hypersensitivity (GO:0001796) 4 0 .00 - < 0.01 1.00E00 1.00E00 virion attachment to host cell (GO:0019062) 9 0 .00 - < 0.01 1.00E00 1.00E00 type IIa hypersensitivity (GO:0001794) 9 0 .00 - < 0.01 1.00E00 1.00E00 intracellular transport of viral protein in host cell (GO:0019060) 2 0 .00 - < 0.01 1.00E00 1.00E00 centriole replication (GO:0007099) 26 0 .01 - < 0.01 1.00E00 1.00E00 centrosome cycle (GO:0007098) 97 0 .03 - < 0.01 1.00E00 1.00E00 nuclear migration (GO:0007097) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of exit from mitosis (GO:0007096) 20 0 .01 - < 0.01 1.00E00 1.00E00 mitotic G2 DNA damage checkpoint signaling (GO:0007095) 37 0 .01 - < 0.01 1.00E00 1.00E00 mitotic spindle assembly checkpoint signaling (GO:0007094) 30 0 .01 - < 0.01 1.00E00 1.00E00 mitotic cell cycle checkpoint signaling (GO:0007093) 118 0 .03 - < 0.01 1.00E00 1.00E00 metaphase/anaphase transition of mitotic cell cycle (GO:0007091) 7 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine hexaphosphate catabolic process (GO:1901909) 5 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine hexaphosphate metabolic process (GO:1901908) 5 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine pentaphosphate catabolic process (GO:1901907) 5 0 .00 - < 0.01 1.00E00 1.00E00 intestinal iron absorption (GO:0160179) 1 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine pentaphosphate metabolic process (GO:1901906) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of autophagosome-lysosome fusion (GO:0160177) 2 0 .00 - < 0.01 1.00E00 1.00E00 magnesium ion transport from cytosol to endoplasmic reticulum (GO:0160176) 1 0 .00 - < 0.01 1.00E00 1.00E00 viral life cycle (GO:0019058) 181 0 .05 - < 0.01 1.00E00 1.00E00 antibody-dependent cellular cytotoxicity (GO:0001788) 9 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell proliferation (GO:0001787) 5 0 .00 - < 0.01 1.00E00 1.00E00 nuclear envelope budding (GO:0140591) 1 0 .00 - < 0.01 1.00E00 1.00E00 B cell apoptotic process (GO:0001783) 12 0 .00 - < 0.01 1.00E00 1.00E00 traversing start control point of mitotic cell cycle (GO:0007089) 4 0 .00 - < 0.01 1.00E00 1.00E00 B cell homeostasis (GO:0001782) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mitotic nuclear division (GO:0007088) 121 0 .04 - < 0.01 1.00E00 1.00E00 neutrophil apoptotic process (GO:0001781) 2 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil homeostasis (GO:0001780) 17 0 .00 - < 0.01 1.00E00 1.00E00 mitotic nuclear membrane reassembly (GO:0007084) 10 0 .00 - < 0.01 1.00E00 1.00E00 Leydig cell differentiation (GO:0033327) 11 0 .00 - < 0.01 1.00E00 1.00E00 cerebrospinal fluid secretion (GO:0033326) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitotic metaphase chromosome alignment (GO:0007080) 57 0 .02 - < 0.01 1.00E00 1.00E00 UDP-D-xylose biosynthetic process (GO:0033320) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell homeostasis (GO:0160165) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD27 signaling pathway (GO:0160162) 5 0 .00 - < 0.01 1.00E00 1.00E00 chromatin looping (GO:0140588) 14 0 .00 - < 0.01 1.00E00 1.00E00 release from viral latency (GO:0019046) 3 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell differentiation (GO:0001779) 16 0 .00 - < 0.01 1.00E00 1.00E00 latent virus replication (GO:0019045) 3 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane repair (GO:0001778) 25 0 .01 - < 0.01 1.00E00 1.00E00 T cell homeostatic proliferation (GO:0001777) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of viral latency (GO:0019043) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte homeostasis (GO:0001776) 100 0 .03 - < 0.01 1.00E00 1.00E00 viral latency (GO:0019042) 5 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance via telomere trimming (GO:0090737) 11 0 .00 - < 0.01 1.00E00 1.00E00 cell activation (GO:0001775) 753 0 .22 - < 0.01 1.00E00 1.00E00 microglial cell activation (GO:0001774) 31 0 .01 - < 0.01 1.00E00 1.00E00 DNA repair complex assembly (GO:0090735) 4 0 .00 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell activation (GO:0001773) 24 0 .01 - < 0.01 1.00E00 1.00E00 mitotic chromosome movement towards spindle pole (GO:0007079) 4 0 .00 - < 0.01 1.00E00 1.00E00 immunological synapse formation (GO:0001771) 13 0 .00 - < 0.01 1.00E00 1.00E00 mitotic nuclear membrane disassembly (GO:0007077) 8 0 .00 - < 0.01 1.00E00 1.00E00 establishment of natural killer cell polarity (GO:0001770) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic chromosome condensation (GO:0007076) 17 0 .00 - < 0.01 1.00E00 1.00E00 UDP-D-xylose metabolic process (GO:0033319) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic spindle assembly checkpoint signaling (GO:0033316) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication checkpoint signaling (GO:0033314) 11 0 .00 - < 0.01 1.00E00 1.00E00 meiotic cell cycle checkpoint signaling (GO:0033313) 8 0 .00 - < 0.01 1.00E00 1.00E00 anterior/posterior pattern specification involved in kidney development (GO:0072098) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branch elongation involved in ureteric bud branching (GO:0072095) 3 0 .00 - < 0.01 1.00E00 1.00E00 ascorbate homeostasis (GO:0140576) 3 0 .00 - < 0.01 1.00E00 1.00E00 establishment of T cell polarity (GO:0001768) 9 0 .00 - < 0.01 1.00E00 1.00E00 establishment of lymphocyte polarity (GO:0001767) 10 0 .00 - < 0.01 1.00E00 1.00E00 metanephric renal vesicle formation (GO:0072093) 4 0 .00 - < 0.01 1.00E00 1.00E00 membrane raft polarization (GO:0001766) 3 0 .00 - < 0.01 1.00E00 1.00E00 ureteric bud invasion (GO:0072092) 3 0 .00 - < 0.01 1.00E00 1.00E00 membrane raft assembly (GO:0001765) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stem cell proliferation (GO:0072091) 82 0 .02 - < 0.01 1.00E00 1.00E00 neuron migration (GO:0001764) 147 0 .04 - < 0.01 1.00E00 1.00E00 morphogenesis of a branching structure (GO:0001763) 177 0 .05 - < 0.01 1.00E00 1.00E00 extraction of mislocalized protein from mitochondrial outer membrane (GO:0140570) 1 0 .00 - < 0.01 1.00E00 1.00E00 beta-alanine transport (GO:0001762) 2 0 .00 - < 0.01 1.00E00 1.00E00 female meiosis sister chromatid cohesion (GO:0007066) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary adaptive immune response involving T cells and B cells (GO:0090721) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary adaptive immune response (GO:0090720) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid cohesion (GO:0007064) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of sister chromatid cohesion (GO:0007063) 17 0 .00 - < 0.01 1.00E00 1.00E00 sister chromatid cohesion (GO:0007062) 48 0 .01 - < 0.01 1.00E00 1.00E00 phytol metabolic process (GO:0033306) 2 0 .00 - < 0.01 1.00E00 1.00E00 male meiosis chromosome segregation (GO:0007060) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle comprising mitosis without cytokinesis (GO:0033301) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of GDF15-GFRAL signaling pathway (GO:0160145) 1 0 .00 - < 0.01 1.00E00 1.00E00 GDF15-GFRAL signaling pathway (GO:0160144) 3 0 .00 - < 0.01 1.00E00 1.00E00 stem cell proliferation (GO:0072089) 76 0 .02 - < 0.01 1.00E00 1.00E00 nephron epithelium morphogenesis (GO:0072088) 70 0 .02 - < 0.01 1.00E00 1.00E00 extraction of mislocalized protein from ER membrane (GO:0140569) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal vesicle development (GO:0072087) 13 0 .00 - < 0.01 1.00E00 1.00E00 extraction of mislocalized protein from membrane (GO:0140568) 2 0 .00 - < 0.01 1.00E00 1.00E00 specification of loop of Henle identity (GO:0072086) 4 0 .00 - < 0.01 1.00E00 1.00E00 organ induction (GO:0001759) 23 0 .01 - < 0.01 1.00E00 1.00E00 somite specification (GO:0001757) 5 0 .00 - < 0.01 1.00E00 1.00E00 somitogenesis (GO:0001756) 60 0 .02 - < 0.01 1.00E00 1.00E00 adaptive immune memory response involving T cells and B cells (GO:0090717) 3 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell migration (GO:0001755) 56 0 .02 - < 0.01 1.00E00 1.00E00 specification of nephron tubule identity (GO:0072081) 5 0 .00 - < 0.01 1.00E00 1.00E00 adaptive immune memory response (GO:0090716) 4 0 .00 - < 0.01 1.00E00 1.00E00 eye photoreceptor cell differentiation (GO:0001754) 53 0 .02 - < 0.01 1.00E00 1.00E00 nephron tubule development (GO:0072080) 85 0 .02 - < 0.01 1.00E00 1.00E00 immunological memory formation process (GO:0090715) 2 0 .00 - < 0.01 1.00E00 1.00E00 chromosome segregation (GO:0007059) 337 0 .10 - < 0.01 1.00E00 1.00E00 immunological memory process (GO:0090713) 6 0 .00 - < 0.01 1.00E00 1.00E00 spindle assembly involved in female meiosis I (GO:0007057) 4 0 .00 - < 0.01 1.00E00 1.00E00 spindle assembly involved in female meiosis (GO:0007056) 12 0 .00 - < 0.01 1.00E00 1.00E00 mitotic spindle organization (GO:0007052) 100 0 .03 - < 0.01 1.00E00 1.00E00 spindle organization (GO:0007051) 170 0 .05 - < 0.01 1.00E00 1.00E00 phospholipase C-activating endothelin receptor signaling pathway (GO:0160135) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of optic nerve formation (GO:2000597) 1 0 .00 - < 0.01 1.00E00 1.00E00 nephron tubule formation (GO:0072079) 19 0 .01 - < 0.01 1.00E00 1.00E00 nephron tubule morphogenesis (GO:0072078) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of optic nerve formation (GO:2000595) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal vesicle morphogenesis (GO:0072077) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric DCT cell differentiation (GO:2000594) 2 0 .00 - < 0.01 1.00E00 1.00E00 nephrogenic mesenchyme development (GO:0072076) 3 0 .00 - < 0.01 1.00E00 1.00E00 metanephric mesenchyme development (GO:0072075) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric DCT cell differentiation (GO:2000592) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney mesenchyme development (GO:0072074) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric mesenchymal cell migration (GO:2000591) 3 0 .00 - < 0.01 1.00E00 1.00E00 kidney epithelium development (GO:0072073) 143 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric mesenchymal cell migration (GO:2000590) 1 0 .00 - < 0.01 1.00E00 1.00E00 kidney interstitial fibroblast differentiation (GO:0072071) 2 0 .00 - < 0.01 1.00E00 1.00E00 loop of Henle development (GO:0072070) 12 0 .00 - < 0.01 1.00E00 1.00E00 lens placode formation (GO:0001743) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle (GO:0007049) 987 0 .29 - < 0.01 1.00E00 1.00E00 cell-substrate junction assembly (GO:0007044) 41 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell junction assembly (GO:0007043) 130 0 .04 - < 0.01 1.00E00 1.00E00 lysosomal lumen acidification (GO:0007042) 24 0 .01 - < 0.01 1.00E00 1.00E00 lysosomal transport (GO:0007041) 129 0 .04 - < 0.01 1.00E00 1.00E00 lysosome organization (GO:0007040) 104 1 .03 + 32.98 2.99E-02 1.00E00 protein-RNA covalent cross-linking repair (GO:0160127) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric mesenchymal cell migration (GO:2000589) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000588) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000587) 4 0 .00 - < 0.01 1.00E00 1.00E00 DCT cell differentiation (GO:0072069) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor receptor-beta signaling pathway (GO:2000586) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of platelet-derived growth factor receptor-alpha signaling pathway (GO:2000584) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor receptor-alpha signaling pathway (GO:2000583) 5 0 .00 - < 0.01 1.00E00 1.00E00 defense response to symbiont (GO:0140546) 890 0 .26 - < 0.01 1.00E00 1.00E00 morphogenesis of a polarized epithelium (GO:0001738) 49 0 .01 - < 0.01 1.00E00 1.00E00 establishment of planar polarity (GO:0001736) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of piRNA transcription (GO:0140543) 1 0 .00 - < 0.01 1.00E00 1.00E00 inner medullary collecting duct development (GO:0072061) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of piRNA transcription (GO:0140542) 1 0 .00 - < 0.01 1.00E00 1.00E00 outer medullary collecting duct development (GO:0072060) 1 0 .00 - < 0.01 1.00E00 1.00E00 piRNA transcription (GO:0140541) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein catabolic process in the vacuole (GO:0007039) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phagocytosis, engulfment (GO:0060099) 15 0 .00 - < 0.01 1.00E00 1.00E00 formation of cytoplasmic translation initiation complex (GO:0001732) 15 0 .00 - < 0.01 1.00E00 1.00E00 formation of translation preinitiation complex (GO:0001731) 10 0 .00 - < 0.01 1.00E00 1.00E00 cytoskeletal rearrangement involved in phagocytosis, engulfment (GO:0060097) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic cytokinesis checkpoint signaling (GO:0044878) 4 0 .00 - < 0.01 1.00E00 1.00E00 vacuolar acidification (GO:0007035) 36 0 .01 - < 0.01 1.00E00 1.00E00 vacuolar transport (GO:0007034) 166 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, glycinergic (GO:0060094) 1 0 .00 - < 0.01 1.00E00 1.00E00 vacuole organization (GO:0007033) 197 1 .06 + 17.41 5.61E-02 1.00E00 endosome organization (GO:0007032) 95 0 .03 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, glycinergic (GO:0060092) 2 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome organization (GO:0007031) 36 0 .01 - < 0.01 1.00E00 1.00E00 lipoprotein localization to membrane (GO:0044873) 1 0 .00 - < 0.01 1.00E00 1.00E00 Golgi organization (GO:0007030) 142 0 .04 - < 0.01 1.00E00 1.00E00 lipoprotein localization (GO:0044872) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral glycoprotein metabolic process (GO:0044871) 2 0 .00 - < 0.01 1.00E00 1.00E00 modulation by host of viral glycoprotein metabolic process (GO:0044870) 2 0 .00 - < 0.01 1.00E00 1.00E00 cortical collecting duct development (GO:0072059) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA biosynthetic process (GO:2000573) 51 0 .01 - < 0.01 1.00E00 1.00E00 renal cortex development (GO:0072055) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000572) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal outer medulla development (GO:0072054) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-4-dependent isotype switching to IgE isotypes (GO:2000571) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal inner medulla development (GO:0072053) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 2 cell activation (GO:2000570) 1 0 .00 - < 0.01 1.00E00 1.00E00 juxtaglomerular apparatus development (GO:0072051) 4 0 .00 - < 0.01 1.00E00 1.00E00 S-shaped body morphogenesis (GO:0072050) 6 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum organization (GO:0007029) 98 0 .03 - < 0.01 1.00E00 1.00E00 cytoplasm organization (GO:0007028) 16 0 .00 - < 0.01 1.00E00 1.00E00 auditory receptor cell stereocilium organization (GO:0060088) 19 0 .01 - < 0.01 1.00E00 1.00E00 relaxation of vascular associated smooth muscle (GO:0060087) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule depolymerization (GO:0007026) 31 0 .01 - < 0.01 1.00E00 1.00E00 circadian temperature homeostasis (GO:0060086) 3 0 .00 - < 0.01 1.00E00 1.00E00 synaptic transmission involved in micturition (GO:0060084) 3 0 .00 - < 0.01 1.00E00 1.00E00 post-chaperonin tubulin folding pathway (GO:0007023) 6 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle contraction involved in micturition (GO:0060083) 3 0 .00 - < 0.01 1.00E00 1.00E00 eye blink reflex (GO:0060082) 1 0 .00 - < 0.01 1.00E00 1.00E00 tubulin complex assembly (GO:0007021) 10 0 .00 - < 0.01 1.00E00 1.00E00 membrane hyperpolarization (GO:0060081) 9 0 .00 - < 0.01 1.00E00 1.00E00 microtubule nucleation (GO:0007020) 30 0 .01 - < 0.01 1.00E00 1.00E00 inhibitory postsynaptic potential (GO:0060080) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein transport into plasma membrane raft (GO:0044861) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to plasma membrane raft (GO:0044860) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotrophin production (GO:0032899) 2 0 .00 - < 0.01 1.00E00 1.00E00 neurotrophin production (GO:0032898) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of viral transcription (GO:0032897) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 2 cell activation (GO:2000569) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of organic acid transport (GO:0032892) 46 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of memory T cell activation (GO:2000568) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of organic acid transport (GO:0032891) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of memory T cell activation (GO:2000567) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of organic acid transport (GO:0032890) 77 0 .02 - < 0.01 1.00E00 1.00E00 type III interferon-mediated signaling pathway (GO:0038196) 11 0 .00 - < 0.01 1.00E00 1.00E00 comma-shaped body morphogenesis (GO:0072049) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000566) 3 0 .00 - < 0.01 1.00E00 1.00E00 urokinase plasminogen activator signaling pathway (GO:0038195) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal system pattern specification (GO:0072048) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000565) 2 0 .00 - < 0.01 1.00E00 1.00E00 thyroid-stimulating hormone signaling pathway (GO:0038194) 2 0 .00 - < 0.01 1.00E00 1.00E00 proximal/distal pattern formation involved in nephron development (GO:0072047) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta T cell proliferation (GO:2000564) 8 0 .00 - < 0.01 1.00E00 1.00E00 thromboxane A2 signaling pathway (GO:0038193) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of planar polarity involved in nephron morphogenesis (GO:0072046) 2 0 .00 - < 0.01 1.00E00 1.00E00 reciprocal homologous recombination (GO:0140527) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000563) 10 0 .00 - < 0.01 1.00E00 1.00E00 gastric inhibitory peptide signaling pathway (GO:0038192) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000562) 12 0 .00 - < 0.01 1.00E00 1.00E00 collecting duct development (GO:0072044) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, alpha-beta T cell proliferation (GO:2000561) 22 0 .01 - < 0.01 1.00E00 1.00E00 conversion of seryl-tRNAsec to selenocys-tRNAsec (GO:0001717) 1 0 .00 - < 0.01 1.00E00 1.00E00 VEGF-activated neuropilin signaling pathway (GO:0038190) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD24 production (GO:2000560) 1 0 .00 - < 0.01 1.00E00 1.00E00 endodermal cell fate specification (GO:0001714) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072040) 4 0 .00 - < 0.01 1.00E00 1.00E00 microtubule depolymerization (GO:0007019) 17 0 .00 - < 0.01 1.00E00 1.00E00 excitatory postsynaptic potential (GO:0060079) 69 0 .02 - < 0.01 1.00E00 1.00E00 ectodermal cell fate commitment (GO:0001712) 1 0 .00 - < 0.01 1.00E00 1.00E00 microtubule-based movement (GO:0007018) 451 0 .13 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic membrane potential (GO:0060078) 106 0 .03 - < 0.01 1.00E00 1.00E00 endodermal cell fate commitment (GO:0001711) 13 0 .00 - < 0.01 1.00E00 1.00E00 microtubule-based process (GO:0007017) 887 0 .26 - < 0.01 1.00E00 1.00E00 mesodermal cell fate commitment (GO:0001710) 14 0 .00 - < 0.01 1.00E00 1.00E00 actin filament organization (GO:0007015) 278 0 .08 - < 0.01 1.00E00 1.00E00 plasma membrane raft organization (GO:0044857) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of resting membrane potential (GO:0060075) 13 0 .00 - < 0.01 1.00E00 1.00E00 actin ubiquitination (GO:0007014) 1 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane raft localization (GO:0044856) 1 0 .00 - < 0.01 1.00E00 1.00E00 synapse maturation (GO:0060074) 17 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane raft distribution (GO:0044855) 1 0 .00 - < 0.01 1.00E00 1.00E00 micturition (GO:0060073) 8 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane raft assembly (GO:0044854) 9 0 .00 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway, planar cell polarity pathway (GO:0060071) 34 0 .01 - < 0.01 1.00E00 1.00E00 cytoskeleton organization (GO:0007010) 1275 0 .37 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway (GO:0060070) 105 0 .03 - < 0.01 1.00E00 1.00E00 regulation of mitotic spindle elongation (GO:0032888) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spindle elongation (GO:0032887) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule-based process (GO:0032886) 274 0 .08 - < 0.01 1.00E00 1.00E00 regulation of polysaccharide biosynthetic process (GO:0032885) 37 0 .01 - < 0.01 1.00E00 1.00E00 neuropilin signaling pathway (GO:0038189) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD24 production (GO:2000559) 1 0 .00 - < 0.01 1.00E00 1.00E00 cholecystokinin signaling pathway (GO:0038188) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immunoglobulin production in mucosal tissue (GO:2000558) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of polysaccharide metabolic process (GO:0032881) 45 0 .01 - < 0.01 1.00E00 1.00E00 regulation of immunoglobulin production in mucosal tissue (GO:2000557) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization (GO:0032880) 896 0 .26 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:0072039) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 1 cell cytokine production (GO:2000556) 8 0 .00 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated bile acid signaling pathway (GO:0038185) 2 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal stem cell maintenance involved in nephron morphogenesis (GO:0072038) 2 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating G protein-coupled bile acid receptor signaling pathway (GO:0038184) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 1 cell cytokine production (GO:2000554) 8 0 .00 - < 0.01 1.00E00 1.00E00 bile acid signaling pathway (GO:0038183) 3 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in renal vesicle formation (GO:0072036) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 2 cell cytokine production (GO:2000553) 9 0 .00 - < 0.01 1.00E00 1.00E00 cell fate determination (GO:0001709) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 2 cell cytokine production (GO:2000552) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell fate specification (GO:0001708) 89 0 .03 - < 0.01 1.00E00 1.00E00 renal vesicle induction (GO:0072034) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 2 cell cytokine production (GO:2000551) 13 0 .00 - < 0.01 1.00E00 1.00E00 mesoderm formation (GO:0001707) 70 0 .02 - < 0.01 1.00E00 1.00E00 nerve growth factor signaling pathway (GO:0038180) 14 0 .00 - < 0.01 1.00E00 1.00E00 renal vesicle formation (GO:0072033) 6 0 .00 - < 0.01 1.00E00 1.00E00 endoderm formation (GO:0001706) 56 0 .02 - < 0.01 1.00E00 1.00E00 proximal convoluted tubule segment 2 development (GO:0072032) 1 0 .00 - < 0.01 1.00E00 1.00E00 ectoderm formation (GO:0001705) 2 0 .00 - < 0.01 1.00E00 1.00E00 formation of primary germ layer (GO:0001704) 121 0 .04 - < 0.01 1.00E00 1.00E00 plasma membrane organization (GO:0007009) 155 0 .05 - < 0.01 1.00E00 1.00E00 gastrulation with mouth forming second (GO:0001702) 28 0 .01 - < 0.01 1.00E00 1.00E00 outer mitochondrial membrane organization (GO:0007008) 14 0 .00 - < 0.01 1.00E00 1.00E00 vagina development (GO:0060068) 10 0 .00 - < 0.01 1.00E00 1.00E00 in utero embryonic development (GO:0001701) 399 1 .12 + 8.60 1.11E-01 1.00E00 inner mitochondrial membrane organization (GO:0007007) 41 0 .01 - < 0.01 1.00E00 1.00E00 estrous cycle (GO:0044849) 15 0 .00 - < 0.01 1.00E00 1.00E00 cervix development (GO:0060067) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial membrane organization (GO:0007006) 114 0 .03 - < 0.01 1.00E00 1.00E00 oviduct development (GO:0060066) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to bicellular tight junction (GO:1902396) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion organization (GO:0007005) 369 0 .11 - < 0.01 1.00E00 1.00E00 uterus development (GO:0060065) 26 1 .01 + > 100 7.56E-03 1.00E00 telomere maintenance via telomerase (GO:0007004) 22 0 .01 - < 0.01 1.00E00 1.00E00 Spemann organizer formation at the anterior end of the primitive streak (GO:0060064) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle G1/S phase transition (GO:0044843) 82 0 .02 - < 0.01 1.00E00 1.00E00 Spemann organizer formation (GO:0060061) 4 0 .00 - < 0.01 1.00E00 1.00E00 nucleolus organization (GO:0007000) 15 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic retina morphogenesis in camera-type eye (GO:0060060) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of localization (GO:0032879) 2016 1 .59 + 1.70 4.61E-01 1.00E00 regulation of establishment or maintenance of cell polarity (GO:0032878) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of DNA endoreduplication (GO:0032877) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA endoreduplication (GO:0032876) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA endoreduplication (GO:0032875) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of stress-activated MAPK cascade (GO:0032874) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of stress-activated MAPK cascade (GO:0032873) 9 0 .00 - < 0.01 1.00E00 1.00E00 neurotrophin signaling pathway (GO:0038179) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell dendrite assembly (GO:2000549) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stress-activated MAPK cascade (GO:0032872) 39 0 .01 - < 0.01 1.00E00 1.00E00 complement component C5a signaling pathway (GO:0038178) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell dendrite assembly (GO:2000548) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell dendrite assembly (GO:2000547) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hormone stimulus (GO:0032870) 563 0 .16 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis to fibroblast growth factor (GO:2000546) 3 0 .00 - < 0.01 1.00E00 1.00E00 nephron morphogenesis (GO:0072028) 72 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell chemotaxis to fibroblast growth factor (GO:2000545) 1 0 .00 - < 0.01 1.00E00 1.00E00 connecting tubule development (GO:0072027) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell chemotaxis to fibroblast growth factor (GO:2000544) 6 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-17A-mediated signaling pathway (GO:0038173) 6 0 .00 - < 0.01 1.00E00 1.00E00 granzyme-mediated programmed cell death signaling pathway (GO:0140507) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gastrulation (GO:2000543) 7 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-33-mediated signaling pathway (GO:0038172) 8 0 .00 - < 0.01 1.00E00 1.00E00 distal convoluted tubule development (GO:0072025) 5 0 .00 - < 0.01 1.00E00 1.00E00 cannabinoid signaling pathway (GO:0038171) 4 0 .00 - < 0.01 1.00E00 1.00E00 macula densa development (GO:0072024) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein geranylgeranylation (GO:2000541) 1 0 .00 - < 0.01 1.00E00 1.00E00 somatostatin signaling pathway (GO:0038170) 6 0 .00 - < 0.01 1.00E00 1.00E00 thick ascending limb development (GO:0072023) 2 0 .00 - < 0.01 1.00E00 1.00E00 descending thin limb development (GO:0072022) 1 0 .00 - < 0.01 1.00E00 1.00E00 ascending thin limb development (GO:0072021) 4 0 .00 - < 0.01 1.00E00 1.00E00 proximal straight tubule development (GO:0072020) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of reticulophagy (GO:0140501) 3 0 .00 - < 0.01 1.00E00 1.00E00 embryonic retina morphogenesis in camera-type eye (GO:0060059) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of reticulophagy (GO:0140500) 3 0 .00 - < 0.01 1.00E00 1.00E00 ceramide 1-phosphate transport (GO:1902389) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process involved in mammary gland involution (GO:0060058) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle G2/M phase transition (GO:0044839) 56 0 .02 - < 0.01 1.00E00 1.00E00 apoptotic process involved in mammary gland involution (GO:0060057) 2 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland involution (GO:0060056) 8 0 .00 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring organization (GO:0044837) 9 0 .00 - < 0.01 1.00E00 1.00E00 angiogenesis involved in wound healing (GO:0060055) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation involved in wound healing (GO:0060054) 10 0 .00 - < 0.01 1.00E00 1.00E00 neurofilament cytoskeleton organization (GO:0060052) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein glycosylation (GO:0060051) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein glycosylation (GO:0060050) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endoribonuclease activity (GO:1902380) 1 0 .00 - < 0.01 1.00E00 1.00E00 modulation by host of viral RNA genome replication (GO:0044830) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to insulin stimulus (GO:0032869) 197 0 .06 - < 0.01 1.00E00 1.00E00 response to insulin (GO:0032868) 266 0 .08 - < 0.01 1.00E00 1.00E00 somatostatin receptor signaling pathway (GO:0038169) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein geranylgeranylation (GO:2000539) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell chemotaxis (GO:2000538) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell chemotaxis (GO:2000537) 2 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin-activated signaling pathway (GO:0038166) 15 0 .00 - < 0.01 1.00E00 1.00E00 proximal convoluted tubule development (GO:0072019) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of entry of bacterium into host cell (GO:2000536) 2 0 .00 - < 0.01 1.00E00 1.00E00 oncostatin-M-mediated signaling pathway (GO:0038165) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of entry of bacterium into host cell (GO:2000535) 7 0 .00 - < 0.01 1.00E00 1.00E00 distal tubule development (GO:0072017) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of renal albumin absorption (GO:2000534) 1 0 .00 - < 0.01 1.00E00 1.00E00 thrombopoietin-mediated signaling pathway (GO:0038163) 7 0 .00 - < 0.01 1.00E00 1.00E00 glomerular parietal epithelial cell development (GO:0072016) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of renal albumin absorption (GO:2000533) 1 0 .00 - < 0.01 1.00E00 1.00E00 erythropoietin-mediated signaling pathway (GO:0038162) 6 0 .00 - < 0.01 1.00E00 1.00E00 podocyte development (GO:0072015) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renal albumin absorption (GO:2000532) 2 0 .00 - < 0.01 1.00E00 1.00E00 prolactin signaling pathway (GO:0038161) 4 0 .00 - < 0.01 1.00E00 1.00E00 proximal tubule development (GO:0072014) 10 0 .00 - < 0.01 1.00E00 1.00E00 CXCL12-activated CXCR4 signaling pathway (GO:0038160) 5 0 .00 - < 0.01 1.00E00 1.00E00 glomerulus vasculature development (GO:0072012) 22 0 .01 - < 0.01 1.00E00 1.00E00 glomerular endothelium development (GO:0072011) 5 0 .00 - < 0.01 1.00E00 1.00E00 glomerular epithelium development (GO:0072010) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein glycosylation (GO:0060049) 9 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle contraction (GO:0060048) 83 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation by host of viral genome replication (GO:0044829) 10 0 .00 - < 0.01 1.00E00 1.00E00 heart contraction (GO:0060047) 99 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral genome replication (GO:0044828) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acrosome reaction (GO:0060046) 16 0 .00 - < 0.01 1.00E00 1.00E00 modulation by host of viral genome replication (GO:0044827) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell proliferation (GO:0060045) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell proliferation (GO:0060044) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of rRNA catabolic process (GO:1902374) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell proliferation (GO:0060043) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA catabolic process (GO:1902373) 79 0 .02 - < 0.01 1.00E00 1.00E00 retina morphogenesis in camera-type eye (GO:0060042) 67 0 .02 - < 0.01 1.00E00 1.00E00 retina development in camera-type eye (GO:0060041) 172 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of tRNA catabolic process (GO:1902371) 4 0 .00 - < 0.01 1.00E00 1.00E00 retinal bipolar neuron differentiation (GO:0060040) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tRNA catabolic process (GO:1902370) 4 0 .00 - < 0.01 1.00E00 1.00E00 meiotic telomere tethering at nuclear periphery (GO:0044821) 5 0 .00 - < 0.01 1.00E00 1.00E00 C-X-C chemokine receptor CXCR4 signaling pathway (GO:0038159) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid dendritic cell chemotaxis (GO:2000529) 1 0 .00 - < 0.01 1.00E00 1.00E00 granulocyte colony-stimulating factor signaling pathway (GO:0038158) 5 0 .00 - < 0.01 1.00E00 1.00E00 granulocyte-macrophage colony-stimulating factor signaling pathway (GO:0038157) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myeloid dendritic cell chemotaxis (GO:2000527) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-3-mediated signaling pathway (GO:0038156) 7 0 .00 - < 0.01 1.00E00 1.00E00 nephron epithelium development (GO:0072009) 111 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation (GO:2000526) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-23-mediated signaling pathway (GO:0038155) 6 0 .00 - < 0.01 1.00E00 1.00E00 glomerular mesangial cell differentiation (GO:0072008) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell costimulation (GO:2000525) 2 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-11-mediated signaling pathway (GO:0038154) 7 0 .00 - < 0.01 1.00E00 1.00E00 mesangial cell differentiation (GO:0072007) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell costimulation (GO:2000524) 3 0 .00 - < 0.01 1.00E00 1.00E00 nephron development (GO:0072006) 141 0 .04 - < 0.01 1.00E00 1.00E00 regulation of T cell costimulation (GO:2000523) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immunological synapse formation (GO:2000522) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney field specification (GO:0072004) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of immunological synapse formation (GO:2000521) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney rudiment formation (GO:0072003) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of immunological synapse formation (GO:2000520) 4 0 .00 - < 0.01 1.00E00 1.00E00 renal system development (GO:0072001) 319 0 .09 - < 0.01 1.00E00 1.00E00 pericardium development (GO:0060039) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of RNA catabolic process (GO:1902369) 92 0 .03 - < 0.01 1.00E00 1.00E00 cardiac muscle cell proliferation (GO:0060038) 25 0 .01 - < 0.01 1.00E00 1.00E00 mitotic G1/S transition checkpoint signaling (GO:0044819) 17 0 .00 - < 0.01 1.00E00 1.00E00 pharyngeal system development (GO:0060037) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Notch signaling pathway involved in somitogenesis (GO:1902367) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic G2/M transition checkpoint (GO:0044818) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of Notch signaling pathway involved in somitogenesis (GO:1902366) 1 0 .00 - < 0.01 1.00E00 1.00E00 notochord cell development (GO:0060035) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to spindle pole body (GO:1902365) 1 0 .00 - < 0.01 1.00E00 1.00E00 notochord cell differentiation (GO:0060034) 1 0 .00 - < 0.01 1.00E00 1.00E00 anatomical structure regression (GO:0060033) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to spindle pole body (GO:1902363) 1 0 .00 - < 0.01 1.00E00 1.00E00 notochord regression (GO:0060032) 1 0 .00 - < 0.01 1.00E00 1.00E00 melanocyte apoptotic process (GO:1902362) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular pH reduction (GO:0032849) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular pH reduction (GO:0032848) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular pH reduction (GO:0032847) 8 0 .00 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 2 signaling pathway (GO:0038148) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 1 cell activation (GO:2000518) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 1 cell activation (GO:2000517) 1 0 .00 - < 0.01 1.00E00 1.00E00 chemokine (C-X-C motif) ligand 12 signaling pathway (GO:0038146) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) 46 0 .01 - < 0.01 1.00E00 1.00E00 macrophage colony-stimulating factor signaling pathway (GO:0038145) 51 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) 84 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of granzyme A production (GO:2000513) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granzyme A production (GO:2000511) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell chemotaxis (GO:2000510) 9 0 .00 - < 0.01 1.00E00 1.00E00 convergent extension involved in organogenesis (GO:0060029) 5 0 .00 - < 0.01 1.00E00 1.00E00 convergent extension involved in axis elongation (GO:0060028) 5 0 .00 - < 0.01 1.00E00 1.00E00 sulfate transmembrane transport (GO:1902358) 16 0 .00 - < 0.01 1.00E00 1.00E00 convergent extension involved in gastrulation (GO:0060027) 5 0 .00 - < 0.01 1.00E00 1.00E00 convergent extension (GO:0060026) 13 0 .00 - < 0.01 1.00E00 1.00E00 oxaloacetate(2-) transmembrane transport (GO:1902356) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic activity (GO:0060025) 3 0 .00 - < 0.01 1.00E00 1.00E00 rhythmic synaptic transmission (GO:0060024) 4 0 .00 - < 0.01 1.00E00 1.00E00 soft palate development (GO:0060023) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleophagy (GO:0044804) 23 0 .01 - < 0.01 1.00E00 1.00E00 hard palate development (GO:0060022) 8 0 .00 - < 0.01 1.00E00 1.00E00 phosphagen metabolic process (GO:0006599) 4 0 .00 - < 0.01 1.00E00 1.00E00 roof of mouth development (GO:0060021) 92 0 .03 - < 0.01 1.00E00 1.00E00 polyamine catabolic process (GO:0006598) 4 0 .00 - < 0.01 1.00E00 1.00E00 Bergmann glial cell differentiation (GO:0060020) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to chloroquine (GO:1902350) 1 0 .00 - < 0.01 1.00E00 1.00E00 spermine biosynthetic process (GO:0006597) 2 0 .00 - < 0.01 1.00E00 1.00E00 polyamine biosynthetic process (GO:0006596) 13 0 .00 - < 0.01 1.00E00 1.00E00 polyamine metabolic process (GO:0006595) 18 0 .01 - < 0.01 1.00E00 1.00E00 ornithine catabolic process (GO:0006593) 1 0 .00 - < 0.01 1.00E00 1.00E00 ornithine biosynthetic process (GO:0006592) 1 0 .00 - < 0.01 1.00E00 1.00E00 glomerular basement membrane development (GO:0032836) 11 0 .00 - < 0.01 1.00E00 1.00E00 ornithine metabolic process (GO:0006591) 7 0 .00 - < 0.01 1.00E00 1.00E00 glomerulus development (GO:0032835) 60 0 .02 - < 0.01 1.00E00 1.00E00 thyroid hormone generation (GO:0006590) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response (GO:0032834) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell chemotaxis (GO:2000509) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response (GO:0032832) 2 0 .00 - < 0.01 1.00E00 1.00E00 ERBB4-ERBB4 signaling pathway (GO:0038138) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell chemotaxis (GO:2000508) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0032831) 7 0 .00 - < 0.01 1.00E00 1.00E00 ERBB2-ERBB4 signaling pathway (GO:0038135) 5 0 .00 - < 0.01 1.00E00 1.00E00 ERBB2-EGFR signaling pathway (GO:0038134) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of blood vessel remodeling (GO:2000504) 2 0 .00 - < 0.01 1.00E00 1.00E00 ERBB2-ERBB3 signaling pathway (GO:0038133) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell chemotaxis (GO:2000503) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell chemotaxis (GO:2000502) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell chemotaxis (GO:2000501) 7 0 .00 - < 0.01 1.00E00 1.00E00 ERBB4 signaling pathway (GO:0038130) 9 0 .00 - < 0.01 1.00E00 1.00E00 radial glial cell differentiation (GO:0060019) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to chloroquine (GO:1902349) 2 0 .00 - < 0.01 1.00E00 1.00E00 astrocyte fate commitment (GO:0060018) 4 0 .00 - < 0.01 1.00E00 1.00E00 parathyroid gland development (GO:0060017) 7 0 .00 - < 0.01 1.00E00 1.00E00 granulosa cell differentiation (GO:0060014) 3 0 .00 - < 0.01 1.00E00 1.00E00 righting reflex (GO:0060013) 8 0 .00 - < 0.01 1.00E00 1.00E00 synaptic transmission, glycinergic (GO:0060012) 3 0 .00 - < 0.01 1.00E00 1.00E00 octopamine biosynthetic process (GO:0006589) 3 0 .00 - < 0.01 1.00E00 1.00E00 Sertoli cell proliferation (GO:0060011) 5 0 .00 - < 0.01 1.00E00 1.00E00 Sertoli cell fate commitment (GO:0060010) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chromosome condensation (GO:1902340) 3 0 .00 - < 0.01 1.00E00 1.00E00 indolalkylamine metabolic process (GO:0006586) 13 0 .00 - < 0.01 1.00E00 1.00E00 dopamine biosynthetic process from tyrosine (GO:0006585) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation (GO:0032829) 8 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine metabolic process (GO:0006584) 47 0 .01 - < 0.01 1.00E00 1.00E00 melanin biosynthetic process from tyrosine (GO:0006583) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell differentiation involved in immune response (GO:0032827) 3 0 .00 - < 0.01 1.00E00 1.00E00 melanin metabolic process (GO:0006582) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell differentiation involved in immune response (GO:0032826) 4 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine catabolic process (GO:0006581) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell differentiation (GO:0032825) 8 0 .00 - < 0.01 1.00E00 1.00E00 ethanolamine metabolic process (GO:0006580) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell differentiation (GO:0032824) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell differentiation (GO:0032823) 13 0 .00 - < 0.01 1.00E00 1.00E00 ERBB3 signaling pathway (GO:0038129) 9 0 .00 - < 0.01 1.00E00 1.00E00 ERBB2 signaling pathway (GO:0038128) 23 0 .01 - < 0.01 1.00E00 1.00E00 ERBB signaling pathway (GO:0038127) 116 0 .03 - < 0.01 1.00E00 1.00E00 toll-like receptor TLR6:TLR2 signaling pathway (GO:0038124) 4 0 .00 - < 0.01 1.00E00 1.00E00 toll-like receptor TLR1:TLR2 signaling pathway (GO:0038123) 1 0 .00 - < 0.01 1.00E00 1.00E00 Sertoli cell development (GO:0060009) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process involved in morphogenesis (GO:1902339) 6 0 .00 - < 0.01 1.00E00 1.00E00 Sertoli cell differentiation (GO:0060008) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in morphogenesis (GO:1902338) 6 0 .00 - < 0.01 1.00E00 1.00E00 linear vestibuloocular reflex (GO:0060007) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in morphogenesis (GO:1902337) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of retinal ganglion cell axon guidance (GO:1902336) 1 0 .00 - < 0.01 1.00E00 1.00E00 vestibular reflex (GO:0060005) 4 0 .00 - < 0.01 1.00E00 1.00E00 reflex (GO:0060004) 22 0 .01 - < 0.01 1.00E00 1.00E00 copper ion export (GO:0060003) 2 0 .00 - < 0.01 1.00E00 1.00E00 amino-acid betaine catabolic process (GO:0006579) 3 0 .00 - < 0.01 1.00E00 1.00E00 amino-acid betaine biosynthetic process (GO:0006578) 7 0 .00 - < 0.01 1.00E00 1.00E00 amino-acid betaine metabolic process (GO:0006577) 17 0 .00 - < 0.01 1.00E00 1.00E00 biogenic amine metabolic process (GO:0006576) 89 0 .03 - < 0.01 1.00E00 1.00E00 modified amino acid metabolic process (GO:0006575) 172 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell proliferation (GO:0032819) 10 0 .00 - < 0.01 1.00E00 1.00E00 valine catabolic process (GO:0006574) 4 0 .00 - < 0.01 1.00E00 1.00E00 valine metabolic process (GO:0006573) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell proliferation (GO:0032817) 12 0 .00 - < 0.01 1.00E00 1.00E00 tyrosine catabolic process (GO:0006572) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell activation (GO:0032816) 21 0 .01 - < 0.01 1.00E00 1.00E00 tyrosine biosynthetic process (GO:0006571) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell activation (GO:0032815) 11 0 .00 - < 0.01 1.00E00 1.00E00 tyrosine metabolic process (GO:0006570) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell activation (GO:0032814) 40 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of epinephrine secretion (GO:0032812) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epinephrine secretion (GO:0032811) 4 0 .00 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 21 signaling pathway (GO:0038116) 4 0 .00 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 19 signaling pathway (GO:0038115) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-21-mediated signaling pathway (GO:0038114) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-9-mediated signaling pathway (GO:0038113) 8 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-8-mediated signaling pathway (GO:0038112) 2 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-7-mediated signaling pathway (GO:0038111) 8 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-2-mediated signaling pathway (GO:0038110) 8 0 .00 - < 0.01 1.00E00 1.00E00 otic vesicle development (GO:0071599) 14 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process via the N-end rule pathway (GO:0071596) 4 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte aggregation (GO:0071593) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-tryptophan catabolic process (GO:0006569) 9 0 .00 - < 0.01 1.00E00 1.00E00 L-tryptophan metabolic process (GO:0006568) 11 0 .00 - < 0.01 1.00E00 1.00E00 threonine catabolic process (GO:0006567) 2 0 .00 - < 0.01 1.00E00 1.00E00 threonine metabolic process (GO:0006566) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-serine catabolic process (GO:0006565) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-serine biosynthetic process (GO:0006564) 6 0 .00 - < 0.01 1.00E00 1.00E00 lacrimal gland development (GO:0032808) 7 0 .00 - < 0.01 1.00E00 1.00E00 L-serine metabolic process (GO:0006563) 12 0 .00 - < 0.01 1.00E00 1.00E00 proline catabolic process (GO:0006562) 4 0 .00 - < 0.01 1.00E00 1.00E00 proline biosynthetic process (GO:0006561) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein particle receptor catabolic process (GO:0032805) 3 0 .00 - < 0.01 1.00E00 1.00E00 proline metabolic process (GO:0006560) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle receptor catabolic process (GO:0032804) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of low-density lipoprotein particle receptor catabolic process (GO:0032803) 6 0 .00 - < 0.01 1.00E00 1.00E00 Kit signaling pathway (GO:0038109) 51 0 .01 - < 0.01 1.00E00 1.00E00 low-density lipoprotein particle receptor catabolic process (GO:0032802) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of appetite by leptin-mediated signaling pathway (GO:0038108) 4 0 .00 - < 0.01 1.00E00 1.00E00 receptor catabolic process (GO:0032801) 19 0 .01 - < 0.01 1.00E00 1.00E00 sequestering of nodal from receptor via nodal binding (GO:0038101) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in nuclear cell cycle DNA replication (GO:1902319) 1 0 .00 - < 0.01 1.00E00 1.00E00 CAAX-box protein processing (GO:0071586) 3 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of cadmium ion (GO:0071585) 4 0 .00 - < 0.01 1.00E00 1.00E00 nuclear DNA replication termination (GO:1902317) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of zinc ion transmembrane import (GO:0071584) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of zinc ion transmembrane transport (GO:0071583) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear cell cycle DNA replication initiation (GO:1902315) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of zinc ion transport (GO:0071582) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of zinc ion transmembrane import (GO:0071581) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of zinc ion transmembrane transport (GO:0071580) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-phenylalanine catabolic process (GO:0006559) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of copper ion transmembrane transport (GO:1902311) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-phenylalanine metabolic process (GO:0006558) 8 0 .00 - < 0.01 1.00E00 1.00E00 S-adenosylmethionine biosynthetic process (GO:0006556) 4 0 .00 - < 0.01 1.00E00 1.00E00 methionine metabolic process (GO:0006555) 16 0 .00 - < 0.01 1.00E00 1.00E00 lysine catabolic process (GO:0006554) 7 0 .00 - < 0.01 1.00E00 1.00E00 lysine metabolic process (GO:0006553) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-leucine catabolic process (GO:0006552) 6 0 .00 - < 0.01 1.00E00 1.00E00 L-leucine metabolic process (GO:0006551) 8 0 .00 - < 0.01 1.00E00 1.00E00 isoleucine catabolic process (GO:0006550) 4 0 .00 - < 0.01 1.00E00 1.00E00 hepatocyte cell migration (GO:0002194) 1 0 .00 - < 0.01 1.00E00 1.00E00 IRES-dependent translational initiation of linear mRNA (GO:0002192) 1 0 .00 - < 0.01 1.00E00 1.00E00 cap-dependent translational initiation (GO:0002191) 6 0 .00 - < 0.01 1.00E00 1.00E00 cap-independent translational initiation (GO:0002190) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of zinc ion transport (GO:0071579) 2 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import across plasma membrane (GO:0071578) 10 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion transmembrane transport (GO:0071577) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of sodium ion transmembrane transport (GO:1902307) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of sodium ion transmembrane transport (GO:1902306) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sodium ion transmembrane transport (GO:1902305) 46 0 .01 - < 0.01 1.00E00 1.00E00 isoleucine metabolic process (GO:0006549) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine catabolic process (GO:0006548) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine metabolic process (GO:0006547) 9 0 .00 - < 0.01 1.00E00 1.00E00 glycine catabolic process (GO:0006546) 3 0 .00 - < 0.01 1.00E00 1.00E00 glycine biosynthetic process (GO:0006545) 5 0 .00 - < 0.01 1.00E00 1.00E00 glycine metabolic process (GO:0006544) 13 0 .00 - < 0.01 1.00E00 1.00E00 glutamine catabolic process (GO:0006543) 3 0 .00 - < 0.01 1.00E00 1.00E00 glutamine biosynthetic process (GO:0006542) 1 0 .00 - < 0.01 1.00E00 1.00E00 glutamine metabolic process (GO:0006541) 19 0 .01 - < 0.01 1.00E00 1.00E00 gamma-aminobutyrate shunt (GO:0006540) 2 0 .00 - < 0.01 1.00E00 1.00E00 translation reinitiation (GO:0002188) 3 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine receptor signaling pathway (GO:0095500) 47 0 .01 - < 0.01 1.00E00 1.00E00 cytoplasmic translational termination (GO:0002184) 1 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasmic translational initiation (GO:0002183) 38 0 .01 - < 0.01 1.00E00 1.00E00 cytoplasmic translational elongation (GO:0002182) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasmic translation (GO:0002181) 132 0 .04 - < 0.01 1.00E00 1.00E00 protein ufmylation (GO:0071569) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to transforming growth factor beta stimulus (GO:0071560) 155 0 .05 - < 0.01 1.00E00 1.00E00 glutamate catabolic process (GO:0006538) 8 0 .00 - < 0.01 1.00E00 1.00E00 glutamate biosynthetic process (GO:0006537) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of attachment of spindle microtubules to kinetochore (GO:0051988) 23 0 .01 - < 0.01 1.00E00 1.00E00 glutamate metabolic process (GO:0006536) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of attachment of spindle microtubules to kinetochore (GO:0051987) 11 0 .00 - < 0.01 1.00E00 1.00E00 cysteine biosynthetic process from serine (GO:0006535) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of attachment of spindle microtubules to kinetochore (GO:0051986) 1 0 .00 - < 0.01 1.00E00 1.00E00 cysteine metabolic process (GO:0006534) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chromosome segregation (GO:0051985) 36 0 .01 - < 0.01 1.00E00 1.00E00 aspartate catabolic process (GO:0006533) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chromosome segregation (GO:0051984) 30 0 .01 - < 0.01 1.00E00 1.00E00 RNA acetylation (GO:1990884) 1 0 .00 - < 0.01 1.00E00 1.00E00 aspartate biosynthetic process (GO:0006532) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chromosome segregation (GO:0051983) 134 0 .04 - < 0.01 1.00E00 1.00E00 aspartate metabolic process (GO:0006531) 8 0 .00 - < 0.01 1.00E00 1.00E00 rRNA acetylation (GO:1990882) 1 0 .00 - < 0.01 1.00E00 1.00E00 asparagine catabolic process (GO:0006530) 1 0 .00 - < 0.01 1.00E00 1.00E00 male germ cell proliferation (GO:0002176) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to paranode region of axon (GO:0002175) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to transforming growth factor beta (GO:0071559) 162 0 .05 - < 0.01 1.00E00 1.00E00 death-inducing signaling complex assembly (GO:0071550) 2 0 .00 - < 0.01 1.00E00 1.00E00 asparagine biosynthetic process (GO:0006529) 2 0 .00 - < 0.01 1.00E00 1.00E00 asparagine metabolic process (GO:0006528) 5 0 .00 - < 0.01 1.00E00 1.00E00 arginine catabolic process (GO:0006527) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-arginine biosynthetic process (GO:0006526) 4 0 .00 - < 0.01 1.00E00 1.00E00 lysophospholipid transport (GO:0051977) 3 0 .00 - < 0.01 1.00E00 1.00E00 arginine metabolic process (GO:0006525) 19 0 .01 - < 0.01 1.00E00 1.00E00 alanine catabolic process (GO:0006524) 5 0 .00 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle cell proliferation (GO:1990874) 6 0 .00 - < 0.01 1.00E00 1.00E00 alanine metabolic process (GO:0006522) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amino acid metabolic process (GO:0006521) 12 0 .00 - < 0.01 1.00E00 1.00E00 amino acid metabolic process (GO:0006520) 272 0 .08 - < 0.01 1.00E00 1.00E00 positive regulation of transmission of nerve impulse (GO:0051971) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transmission of nerve impulse (GO:0051970) 6 0 .00 - < 0.01 1.00E00 1.00E00 desmosome maintenance (GO:0002160) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to dexamethasone stimulus (GO:0071549) 30 0 .01 - < 0.01 1.00E00 1.00E00 response to dexamethasone (GO:0071548) 47 0 .01 - < 0.01 1.00E00 1.00E00 inositol phosphate catabolic process (GO:0071545) 2 0 .00 - < 0.01 1.00E00 1.00E00 diphosphoinositol polyphosphate catabolic process (GO:0071544) 1 0 .00 - < 0.01 1.00E00 1.00E00 diphosphoinositol polyphosphate metabolic process (GO:0071543) 5 0 .00 - < 0.01 1.00E00 1.00E00 dopaminergic neuron differentiation (GO:0071542) 36 0 .01 - < 0.01 1.00E00 1.00E00 peptide metabolic process (GO:0006518) 63 0 .02 - < 0.01 1.00E00 1.00E00 regulation of transmission of nerve impulse (GO:0051969) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to chemokine (GO:1990869) 82 0 .02 - < 0.01 1.00E00 1.00E00 protein deglycosylation (GO:0006517) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, glutamatergic (GO:0051968) 36 0 .01 - < 0.01 1.00E00 1.00E00 response to chemokine (GO:1990868) 82 0 .02 - < 0.01 1.00E00 1.00E00 glycoprotein catabolic process (GO:0006516) 36 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission, glutamatergic (GO:0051967) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein quality control for misfolded or incompletely synthesized proteins (GO:0006515) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, glutamatergic (GO:0051966) 77 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of synapse assembly (GO:0051965) 65 0 .02 - < 0.01 1.00E00 1.00E00 protein monoubiquitination (GO:0006513) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of synapse assembly (GO:0051964) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synapse assembly (GO:0051963) 167 0 .05 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process (GO:0006511) 550 0 .16 - < 0.01 1.00E00 1.00E00 positive regulation of nervous system development (GO:0051962) 280 0 .08 - < 0.01 1.00E00 1.00E00 desmosome assembly (GO:0002159) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nervous system development (GO:0051961) 143 0 .04 - < 0.01 1.00E00 1.00E00 osteoclast proliferation (GO:0002158) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nervous system development (GO:0051960) 445 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of thyroid hormone receptor signaling pathway (GO:0002157) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thyroid hormone receptor signaling pathway (GO:0002155) 6 0 .00 - < 0.01 1.00E00 1.00E00 thyroid hormone receptor signaling pathway (GO:0002154) 3 0 .00 - < 0.01 1.00E00 1.00E00 bile acid conjugation (GO:0002152) 1 0 .00 - < 0.01 1.00E00 1.00E00 otolith mineralization (GO:0045299) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to centrosome (GO:0071539) 26 0 .01 - < 0.01 1.00E00 1.00E00 mRNA cis splicing, via spliceosome (GO:0045292) 26 0 .01 - < 0.01 1.00E00 1.00E00 membrane protein ectodomain proteolysis (GO:0006509) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of relaxation of cardiac muscle (GO:1901899) 2 0 .00 - < 0.01 1.00E00 1.00E00 proteolysis (GO:0006508) 1266 0 .37 - < 0.01 1.00E00 1.00E00 negative regulation of relaxation of cardiac muscle (GO:1901898) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to endothelin (GO:1990859) 2 0 .00 - < 0.01 1.00E00 1.00E00 methotrexate transport (GO:0051958) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of relaxation of cardiac muscle (GO:1901897) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to lectin (GO:1990858) 22 0 .01 - < 0.01 1.00E00 1.00E00 GPI anchor biosynthetic process (GO:0006506) 32 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of amino acid transport (GO:0051957) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901896) 2 0 .00 - < 0.01 1.00E00 1.00E00 GPI anchor metabolic process (GO:0006505) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of amino acid transport (GO:0051956) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901895) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amino acid transport (GO:0051955) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of ATPase-coupled calcium transmembrane transporter activity (GO:1901894) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amine transport (GO:0051954) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of amine transport (GO:0051953) 26 0 .01 - < 0.01 1.00E00 1.00E00 C-terminal protein lipidation (GO:0006501) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amine transport (GO:0051952) 84 0 .02 - < 0.01 1.00E00 1.00E00 hypochlorous acid biosynthetic process (GO:0002149) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal protein palmitoylation (GO:0006500) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051951) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell junction assembly (GO:1901890) 109 0 .03 - < 0.01 1.00E00 1.00E00 hypochlorous acid metabolic process (GO:0002148) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA wobble position uridine thiolation (GO:0002143) 4 0 .00 - < 0.01 1.00E00 1.00E00 cementum mineralization (GO:0071529) 6 0 .00 - < 0.01 1.00E00 1.00E00 tRNA re-export from nucleus (GO:0071528) 1 0 .00 - < 0.01 1.00E00 1.00E00 semaphorin-plexin signaling pathway (GO:0071526) 45 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cell junction assembly (GO:1901889) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell junction assembly (GO:1901888) 264 0 .08 - < 0.01 1.00E00 1.00E00 vacuolar localization (GO:1990849) 63 0 .02 - < 0.01 1.00E00 1.00E00 regulation of glutamate uptake involved in transmission of nerve impulse (GO:0051946) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of catecholamine uptake involved in synaptic transmission (GO:0051945) 1 0 .00 - < 0.01 1.00E00 1.00E00 adaptive thermogenesis (GO:1990845) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of catecholamine uptake involved in synaptic transmission (GO:0051944) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amino acid uptake involved in synaptic transmission (GO:0051943) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein depolymerization (GO:1901881) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of amino acid uptake involved in synaptic transmission (GO:0051941) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein depolymerization (GO:1901880) 70 0 .02 - < 0.01 1.00E00 1.00E00 retinoic acid biosynthetic process (GO:0002138) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to lectin (GO:1990840) 22 0 .01 - < 0.01 1.00E00 1.00E00 wobble position ribose methylation (GO:0002130) 2 0 .00 - < 0.01 1.00E00 1.00E00 genomic imprinting (GO:0071514) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein depolymerization (GO:1901879) 94 0 .03 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid import (GO:0051939) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to endothelin (GO:1990839) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-glutamate import (GO:0051938) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion binding (GO:1901877) 2 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine transport (GO:0051937) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of calcium ion binding (GO:1901876) 2 0 .00 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid reuptake (GO:0051936) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of post-translational protein modification (GO:1901875) 132 0 .04 - < 0.01 1.00E00 1.00E00 glutamate reuptake (GO:0051935) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of post-translational protein modification (GO:1901874) 91 0 .03 - < 0.01 1.00E00 1.00E00 catecholamine uptake involved in synaptic transmission (GO:0051934) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of post-translational protein modification (GO:1901873) 242 0 .07 - < 0.01 1.00E00 1.00E00 response to odorant (GO:1990834) 4 0 .00 - < 0.01 1.00E00 1.00E00 amino acid neurotransmitter reuptake (GO:0051933) 6 0 .00 - < 0.01 1.00E00 1.00E00 synaptic transmission, GABAergic (GO:0051932) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of sensory perception (GO:0051931) 21 0 .01 - < 0.01 1.00E00 1.00E00 tRNA nucleoside ribose methylation (GO:0002128) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sensory perception of pain (GO:0051930) 21 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to leukemia inhibitory factor (GO:1990830) 98 0 .03 - < 0.01 1.00E00 1.00E00 tRNA wobble base cytosine methylation (GO:0002127) 1 0 .00 - < 0.01 1.00E00 1.00E00 maternal aggressive behavior (GO:0002125) 3 0 .00 - < 0.01 1.00E00 1.00E00 inter-male aggressive behavior (GO:0002121) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to mycophenolic acid (GO:0071506) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to mycophenolic acid (GO:0071505) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to heparin (GO:0071504) 3 0 .00 - < 0.01 1.00E00 1.00E00 secretion of lysosomal enzymes (GO:0033299) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to heparin (GO:0071503) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to temperature stimulus (GO:0071502) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to sterol depletion (GO:0071501) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nitrosative stress (GO:0071500) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transport (GO:0051928) 116 0 .03 - < 0.01 1.00E00 1.00E00 hepatocyte dedifferentiation (GO:1990828) 1 0 .00 - < 0.01 1.00E00 1.00E00 T-tubule organization (GO:0033292) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion transport (GO:0051926) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of calcium ion transport (GO:0051924) 242 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of muscle tissue development (GO:1901863) 24 0 .01 - < 0.01 1.00E00 1.00E00 sulfation (GO:0051923) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of muscle tissue development (GO:1901862) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to leukemia inhibitory factor (GO:1990823) 100 0 .03 - < 0.01 1.00E00 1.00E00 regulation of muscle tissue development (GO:1901861) 45 0 .01 - < 0.01 1.00E00 1.00E00 basic amino acid transmembrane transport (GO:1990822) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial DNA metabolic process (GO:1901860) 2 0 .00 - < 0.01 1.00E00 1.00E00 aggressive behavior (GO:0002118) 8 0 .00 - < 0.01 1.00E00 1.00E00 store-operated calcium entry (GO:0002115) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial DNA metabolic process (GO:1901859) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fibrinolysis (GO:0051919) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial DNA metabolic process (GO:1901858) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibrinolysis (GO:0051918) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular respiration (GO:1901857) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibrinolysis (GO:0051917) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cellular respiration (GO:1901856) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin D (GO:0033280) 30 0 .01 - < 0.01 1.00E00 1.00E00 induction of synaptic plasticity by chemical substance (GO:0051915) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic plasticity by chemical substance (GO:0051914) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic plasticity by chemical substance (GO:0051913) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA wobble cytosine modification (GO:0002101) 3 0 .00 - < 0.01 1.00E00 1.00E00 tRNA wobble adenosine to inosine editing (GO:0002100) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation in midbrain (GO:0033278) 5 0 .00 - < 0.01 1.00E00 1.00E00 actin-myosin filament sliding (GO:0033275) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin B2 (GO:0033274) 1 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum tubular network membrane organization (GO:1990809) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin (GO:0033273) 84 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication by electrical coupling involved in cardiac conduction (GO:1901846) 2 0 .00 - < 0.01 1.00E00 1.00E00 ligand-gated ion channel signaling pathway (GO:1990806) 44 0 .01 - < 0.01 1.00E00 1.00E00 establishment of pigment granule localization (GO:0051905) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell communication by electrical coupling involved in cardiac conduction (GO:1901844) 11 0 .00 - < 0.01 1.00E00 1.00E00 pigment granule transport (GO:0051904) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of high voltage-gated calcium channel activity (GO:1901843) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of high voltage-gated calcium channel activity (GO:1901842) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial depolarization (GO:0051902) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of high voltage-gated calcium channel activity (GO:1901841) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial depolarization (GO:0051901) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial depolarization (GO:0051900) 21 0 .01 - < 0.01 1.00E00 1.00E00 protein palmitoleylation (GO:0045234) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA localization to nucleus (GO:0090685) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901838) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901837) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear cell cycle DNA replication (GO:0033262) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription of nucleolar large rRNA by RNA polymerase I (GO:1901836) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA (GO:1901835) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear DNA replication (GO:0033260) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of deadenylation-independent decapping of nuclear-transcribed mRNA (GO:1901834) 1 0 .00 - < 0.01 1.00E00 1.00E00 external encapsulating structure organization (GO:0045229) 283 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of CD4 production (GO:0045225) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion transmembrane transport via low voltage-gated calcium channel (GO:0090676) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermicrovillar adhesion (GO:0090675) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD4 production (GO:0045223) 1 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell-matrix adhesion (GO:0090673) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of FasL production (GO:0045221) 1 0 .00 - < 0.01 1.00E00 1.00E00 telomerase RNA localization (GO:0090672) 7 0 .00 - < 0.01 1.00E00 1.00E00 telomerase RNA localization to Cajal body (GO:0090671) 7 0 .00 - < 0.01 1.00E00 1.00E00 RNA localization to Cajal body (GO:0090670) 11 0 .00 - < 0.01 1.00E00 1.00E00 zeaxanthin biosynthetic process (GO:1901827) 1 0 .00 - < 0.01 1.00E00 1.00E00 zeaxanthin catabolic process (GO:1901826) 1 0 .00 - < 0.01 1.00E00 1.00E00 zeaxanthin metabolic process (GO:1901825) 2 0 .00 - < 0.01 1.00E00 1.00E00 chordate pharynx development (GO:0160093) 3 0 .00 - < 0.01 1.00E00 1.00E00 spliceosome-depend formation of circular RNA (GO:0160091) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of FasL production (GO:0045219) 1 0 .00 - < 0.01 1.00E00 1.00E00 zonula adherens maintenance (GO:0045218) 3 0 .00 - < 0.01 1.00E00 1.00E00 telomerase RNA stabilization (GO:0090669) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell junction maintenance (GO:0045217) 20 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell junction organization (GO:0045216) 184 0 .05 - < 0.01 1.00E00 1.00E00 scaRNA localization to Cajal body (GO:0090666) 5 0 .00 - < 0.01 1.00E00 1.00E00 sarcomere organization (GO:0045214) 44 0 .01 - < 0.01 1.00E00 1.00E00 galanin-activated signaling pathway (GO:0090663) 2 0 .00 - < 0.01 1.00E00 1.00E00 FasL biosynthetic process (GO:0045210) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebrospinal fluid circulation (GO:0090660) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amine catabolic process (GO:0033242) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amine catabolic process (GO:0033241) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amine metabolic process (GO:0033240) 7 0 .00 - < 0.01 1.00E00 1.00E00 spermatid cytoplasm removal during spermiation of flagellated sperm (GO:0160087) 1 0 .00 - < 0.01 1.00E00 1.00E00 beta-carotene metabolic process (GO:1901810) 1 0 .00 - < 0.01 1.00E00 1.00E00 gastrin-induced gastric acid secretion (GO:0001698) 1 0 .00 - < 0.01 1.00E00 1.00E00 walking behavior (GO:0090659) 40 0 .01 - < 0.01 1.00E00 1.00E00 gastric acid secretion (GO:0001696) 8 0 .00 - < 0.01 1.00E00 1.00E00 telomeric loop disassembly (GO:0090657) 10 0 .00 - < 0.01 1.00E00 1.00E00 histamine catabolic process (GO:0001695) 1 0 .00 - < 0.01 1.00E00 1.00E00 t-circle formation (GO:0090656) 11 0 .00 - < 0.01 1.00E00 1.00E00 histamine biosynthetic process (GO:0001694) 2 0 .00 - < 0.01 1.00E00 1.00E00 histamine metabolic process (GO:0001692) 6 0 .00 - < 0.01 1.00E00 1.00E00 establishment of neuroblast polarity (GO:0045200) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amine metabolic process (GO:0033239) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oxygen-glucose deprivation (GO:0090650) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amine metabolic process (GO:0033238) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein sumoylation (GO:0033235) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein sumoylation (GO:0033234) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein sumoylation (GO:0033233) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipid droplet fusion (GO:0160078) 1 0 .00 - < 0.01 1.00E00 1.00E00 beta-glucoside catabolic process (GO:1901805) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipid droplet fusion (GO:0160077) 5 0 .00 - < 0.01 1.00E00 1.00E00 beta-glucoside metabolic process (GO:1901804) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of non-canonical inflammasome complex assembly (GO:0160076) 1 0 .00 - < 0.01 1.00E00 1.00E00 non-canonical inflammasome complex assembly (GO:0160075) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proteasomal protein catabolic process (GO:1901800) 116 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic spindle assembly checkpoint signaling (GO:0140499) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to oxygen-glucose deprivation (GO:0090649) 10 0 .00 - < 0.01 1.00E00 1.00E00 migracytosis (GO:0140495) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to environmental enrichment (GO:0090648) 2 0 .00 - < 0.01 1.00E00 1.00E00 very long-chain fatty acid beta-oxidation (GO:0140493) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA processing (GO:0090646) 13 0 .00 - < 0.01 1.00E00 1.00E00 tRNA 5'-leader removal (GO:0001682) 13 0 .00 - < 0.01 1.00E00 1.00E00 tRNA 3'-terminal CCA addition (GO:0001680) 1 0 .00 - < 0.01 1.00E00 1.00E00 dsRNA transport (GO:0033227) 3 0 .00 - < 0.01 1.00E00 1.00E00 surfactant secretion (GO:0160069) 2 0 .00 - < 0.01 1.00E00 1.00E00 multi-pass transmembrane protein insertion into ER membrane (GO:0160063) 9 0 .00 - < 0.01 1.00E00 1.00E00 intracellular glucose homeostasis (GO:0001678) 105 0 .03 - < 0.01 1.00E00 1.00E00 5-aminolevulinic acid import across plasma membrane (GO:0140484) 1 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty acid metabolic process (GO:0001676) 105 0 .03 - < 0.01 1.00E00 1.00E00 acrosome assembly (GO:0001675) 37 0 .01 - < 0.01 1.00E00 1.00E00 activation of GTPase activity (GO:0090630) 32 0 .01 - < 0.01 1.00E00 1.00E00 reductive iron assimilation (GO:0033215) 1 0 .00 - < 0.01 1.00E00 1.00E00 iron import into cell (GO:0033212) 7 0 .00 - < 0.01 1.00E00 1.00E00 adiponectin-activated signaling pathway (GO:0033211) 8 0 .00 - < 0.01 1.00E00 1.00E00 leptin-mediated signaling pathway (GO:0033210) 10 0 .00 - < 0.01 1.00E00 1.00E00 microfibril assembly (GO:0160054) 1 0 .00 - < 0.01 1.00E00 1.00E00 ameboidal-type cell migration (GO:0001667) 139 0 .04 - < 0.01 1.00E00 1.00E00 response to hypoxia (GO:0001666) 291 0 .08 - < 0.01 1.00E00 1.00E00 siRNA-mediated gene silencing by mRNA destabilization (GO:0090625) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral fear response (GO:0001662) 34 0 .01 - < 0.01 1.00E00 1.00E00 conditioned taste aversion (GO:0001661) 3 0 .00 - < 0.01 1.00E00 1.00E00 fever generation (GO:0001660) 3 0 .00 - < 0.01 1.00E00 1.00E00 tumor necrosis factor-mediated signaling pathway (GO:0033209) 52 0 .02 - < 0.01 1.00E00 1.00E00 meiotic cytokinesis (GO:0033206) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cGAS/STING signaling pathway (GO:0160049) 15 0 .00 - < 0.01 1.00E00 1.00E00 mitocytosis (GO:0160040) 5 0 .00 - < 0.01 1.00E00 1.00E00 GCN2-mediated signaling (GO:0140469) 4 0 .00 - < 0.01 1.00E00 1.00E00 HRI-mediated signaling (GO:0140468) 7 0 .00 - < 0.01 1.00E00 1.00E00 integrated stress response signaling (GO:0140467) 36 0 .01 - < 0.01 1.00E00 1.00E00 temperature homeostasis (GO:0001659) 34 0 .01 - < 0.01 1.00E00 1.00E00 iron-sulfur cluster export from the mitochondrion (GO:0140466) 1 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in ureteric bud morphogenesis (GO:0001658) 45 0 .01 - < 0.01 1.00E00 1.00E00 ureteric bud development (GO:0001657) 88 0 .03 - < 0.01 1.00E00 1.00E00 metanephros development (GO:0001656) 86 0 .03 - < 0.01 1.00E00 1.00E00 urogenital system development (GO:0001655) 63 1 .02 + 54.44 1.82E-02 1.00E00 mitochondrial mRNA 3'-end processing (GO:0090616) 1 0 .00 - < 0.01 1.00E00 1.00E00 pericentric heterochromatin organization (GO:0140462) 1 0 .00 - < 0.01 1.00E00 1.00E00 eye development (GO:0001654) 406 0 .12 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA processing (GO:0090615) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to Gram-negative bacterium (GO:0140460) 1 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway (GO:0090611) 5 0 .00 - < 0.01 1.00E00 1.00E00 trans-Golgi network to recycling endosome transport (GO:0044795) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation by host of viral process (GO:0044794) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral process (GO:0044793) 15 0 .00 - < 0.01 1.00E00 1.00E00 suppression of viral release by host (GO:0044790) 17 0 .00 - < 0.01 1.00E00 1.00E00 somatic sensory system development (GO:0160038) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to Gram-positive bacterium (GO:0140459) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-18-mediated signaling pathway (GO:2000494) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-18-mediated signaling pathway (GO:2000493) 1 0 .00 - < 0.01 1.00E00 1.00E00 osteoblast differentiation (GO:0001649) 145 0 .04 - < 0.01 1.00E00 1.00E00 regulation of interleukin-18-mediated signaling pathway (GO:2000492) 4 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasm protein quality control (GO:0140455) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell activation (GO:2000491) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein aggregate center assembly (GO:0140454) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatic stellate cell activation (GO:2000490) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to Golgi apparatus (GO:0140450) 3 0 .00 - < 0.01 1.00E00 1.00E00 modulation by host of viral process (GO:0044788) 48 0 .01 - < 0.01 1.00E00 1.00E00 enucleation (GO:0090601) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication (GO:0044786) 27 0 .01 - < 0.01 1.00E00 1.00E00 metaphase/anaphase transition of meiotic cell cycle (GO:0044785) 1 0 .00 - < 0.01 1.00E00 1.00E00 metaphase/anaphase transition of cell cycle (GO:0044784) 8 0 .00 - < 0.01 1.00E00 1.00E00 cilium organization (GO:0044782) 385 0 .11 - < 0.01 1.00E00 1.00E00 sensory perception of itch (GO:0160025) 2 0 .00 - < 0.01 1.00E00 1.00E00 Leydig cell proliferation (GO:0160024) 2 0 .00 - < 0.01 1.00E00 1.00E00 sneeze reflex (GO:0160023) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell activation (GO:2000489) 7 0 .00 - < 0.01 1.00E00 1.00E00 maternal-to-zygotic transition of gene expression (GO:0160021) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ferroptosis (GO:0160020) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamine transport (GO:2000487) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glutamine transport (GO:2000486) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamine transport (GO:2000485) 3 0 .00 - < 0.01 1.00E00 1.00E00 signaling receptor ligand precursor processing (GO:0140448) 43 0 .01 - < 0.01 1.00E00 1.00E00 cytokine precursor processing (GO:0140447) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cAMP-dependent protein kinase activity (GO:2000481) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cAMP-dependent protein kinase activity (GO:2000480) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic spindle checkpoint signaling (GO:0044779) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA integrity checkpoint signaling (GO:0044778) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA integrity checkpoint signaling (GO:0044774) 74 0 .02 - < 0.01 1.00E00 1.00E00 mitotic DNA damage checkpoint signaling (GO:0044773) 70 0 .02 - < 0.01 1.00E00 1.00E00 mitotic cell cycle phase transition (GO:0044772) 147 0 .04 - < 0.01 1.00E00 1.00E00 meiotic cell cycle phase transition (GO:0044771) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle phase transition (GO:0044770) 160 0 .05 - < 0.01 1.00E00 1.00E00 regulation of cAMP-dependent protein kinase activity (GO:2000479) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric podocyte development (GO:2000478) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric podocyte development (GO:2000477) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of opioid receptor signaling pathway (GO:2000476) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein stearoylation (GO:0140438) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of opioid receptor signaling pathway (GO:2000474) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic stem cell migration (GO:2000473) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic stem cell migration (GO:2000471) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peroxidase activity (GO:2000470) 2 0 .00 - < 0.01 1.00E00 1.00E00 suppression of symbiont entry into host (GO:0052373) 1 0 .00 - < 0.01 1.00E00 1.00E00 modulation by symbiont of entry into host (GO:0052372) 28 0 .01 - < 0.01 1.00E00 1.00E00 low-density lipoprotein receptor particle metabolic process (GO:0032799) 1 0 .00 - < 0.01 1.00E00 1.00E00 glutathione import into mitochondrion (GO:0160007) 1 0 .00 - < 0.01 1.00E00 1.00E00 Fc receptor-mediated immune complex endocytosis (GO:0160006) 3 0 .00 - < 0.01 1.00E00 1.00E00 uropod organization (GO:0032796) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CREB transcription factor activity (GO:0032793) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CREB transcription factor activity (GO:0032792) 4 0 .00 - < 0.01 1.00E00 1.00E00 sequestering of BMP from receptor via BMP binding (GO:0038098) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway (GO:0038097) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen (starch) synthase activity (GO:2000467) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribosome disassembly (GO:0032790) 41 0 .01 - < 0.01 1.00E00 1.00E00 Fc-gamma receptor signaling pathway involved in phagocytosis (GO:0038096) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen (starch) synthase activity (GO:2000466) 3 0 .00 - < 0.01 1.00E00 1.00E00 Fc-epsilon receptor signaling pathway (GO:0038095) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glycogen (starch) synthase activity (GO:2000465) 5 0 .00 - < 0.01 1.00E00 1.00E00 Fc-gamma receptor signaling pathway (GO:0038094) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of astrocyte chemotaxis (GO:2000464) 1 0 .00 - < 0.01 1.00E00 1.00E00 Fc receptor signaling pathway (GO:0038093) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of excitatory postsynaptic potential (GO:2000463) 35 0 .01 - < 0.01 1.00E00 1.00E00 nodal signaling pathway (GO:0038092) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway (GO:0038091) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to human chorionic gonadotropin (GO:0044752) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to human chorionic gonadotropin stimulus (GO:0044751) 2 0 .00 - < 0.01 1.00E00 1.00E00 unsaturated monocarboxylic acid metabolic process (GO:0032789) 1 0 .00 - < 0.01 1.00E00 1.00E00 saturated monocarboxylic acid metabolic process (GO:0032788) 1 0 .00 - < 0.01 1.00E00 1.00E00 monocarboxylic acid metabolic process (GO:0032787) 507 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated transcription, elongation (GO:0032786) 58 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated transcription, elongation (GO:0032785) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA-templated transcription elongation (GO:0032784) 99 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of cell migration by vascular endothelial growth factor signaling pathway (GO:0038089) 1 0 .00 - < 0.01 1.00E00 1.00E00 bile acid secretion (GO:0032782) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of astrocyte chemotaxis (GO:2000458) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ATP-dependent activity (GO:0032781) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ATP-dependent activity (GO:0032780) 15 0 .00 - < 0.01 1.00E00 1.00E00 VEGF-activated platelet-derived growth factor receptor signaling pathway (GO:0038086) 3 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor signaling pathway (GO:0038084) 64 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000454) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine autophosphorylation (GO:0038083) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation (GO:2000452) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000451) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication maintenance of fidelity (GO:1902298) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in cell cycle DNA replication (GO:1902296) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication termination (GO:1902294) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle DNA replication initiation (GO:1902292) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein transmembrane import into intracellular organelle (GO:0044743) 39 0 .01 - < 0.01 1.00E00 1.00E00 RNA biosynthetic process (GO:0032774) 1386 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of tyrosinase activity (GO:0032773) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta T cell extravasation (GO:2000449) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage migration inhibitory factor signaling pathway (GO:2000448) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monooxygenase activity (GO:0032770) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macrophage migration inhibitory factor signaling pathway (GO:2000446) 3 0 .00 - < 0.01 1.00E00 1.00E00 semaphorin-plexin signaling pathway involved in axon guidance (GO:1902287) 3 0 .00 - < 0.01 1.00E00 1.00E00 semaphorin-plexin signaling pathway involved in neuron projection guidance (GO:1902285) 3 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection extension involved in neuron projection guidance (GO:1902284) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of primary amine oxidase activity (GO:1902283) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monooxygenase activity (GO:0032769) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell cytokine production (GO:0032765) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell cytokine production (GO:0032764) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell cytokine production (GO:0032763) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte extravasation (GO:2000439) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte extravasation (GO:2000438) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphotoxin A production (GO:0032761) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of monocyte extravasation (GO:2000437) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tumor necrosis factor production (GO:0032760) 106 0 .03 - < 0.01 1.00E00 1.00E00 p38MAPK cascade (GO:0038066) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein neddylation (GO:2000436) 5 0 .00 - < 0.01 1.00E00 1.00E00 collagen-activated signaling pathway (GO:0038065) 62 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of protein neddylation (GO:2000435) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein neddylation (GO:2000434) 20 0 .01 - < 0.01 1.00E00 1.00E00 collagen-activated tyrosine kinase receptor signaling pathway (GO:0038063) 58 0 .02 - < 0.01 1.00E00 1.00E00 non-canonical NF-kappaB signal transduction (GO:0038061) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cytokinesis, actomyosin contractile ring assembly (GO:2000431) 1 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide-cGMP-mediated signaling (GO:0038060) 10 0 .00 - < 0.01 1.00E00 1.00E00 epigenetic programing of male pronucleus (GO:0044727) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chromatin organization (GO:1902275) 23 0 .01 - < 0.01 1.00E00 1.00E00 epigenetic programing of female pronucleus (GO:0044726) 4 0 .00 - < 0.01 1.00E00 1.00E00 epigenetic programming in the zygotic pronuclei (GO:0044725) 15 0 .00 - < 0.01 1.00E00 1.00E00 (R)-carnitine transmembrane transport (GO:1902270) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, substrate release (GO:0044721) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of TRAIL production (GO:0032759) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-8 production (GO:0032757) 65 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-6 production (GO:0032755) 99 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-5 production (GO:0032754) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-4 production (GO:0032753) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-3 production (GO:0032752) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic cell clearance (GO:2000427) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic cell clearance (GO:2000426) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic cell clearance (GO:2000425) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil chemotaxis (GO:2000424) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eosinophil chemotaxis (GO:2000422) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil extravasation (GO:2000420) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of polyamine transmembrane transport (GO:1902269) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of polyamine transmembrane transport (GO:1902268) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of polyamine transmembrane transport (GO:1902267) 4 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process involved in embryonic digit morphogenesis (GO:1902263) 3 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process involved in blood vessel morphogenesis (GO:1902262) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of delayed rectifier potassium channel activity (GO:1902261) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of delayed rectifier potassium channel activity (GO:1902260) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-23 production (GO:0032747) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-21 production (GO:0032745) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-2 production (GO:0032743) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of eosinophil extravasation (GO:2000419) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil migration (GO:2000418) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-18 production (GO:0032741) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil migration (GO:2000417) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-17 production (GO:0032740) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of eosinophil migration (GO:2000416) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fibronectin-dependent thymocyte migration (GO:2000415) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-5-mediated signaling pathway (GO:0038043) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibronectin-dependent thymocyte migration (GO:2000413) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of thymocyte migration (GO:2000412) 3 0 .00 - < 0.01 1.00E00 1.00E00 cross-receptor inhibition within G protein-coupled receptor heterodimer (GO:0038041) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thymocyte migration (GO:2000410) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of delayed rectifier potassium channel activity (GO:1902259) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in outflow tract morphogenesis (GO:1902257) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in outflow tract morphogenesis (GO:1902256) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902255) 6 0 .00 - < 0.01 1.00E00 1.00E00 multi-multicellular organism process (GO:0044706) 204 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254) 22 0 .01 - < 0.01 1.00E00 1.00E00 phytoalexin metabolic process (GO:0052314) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253) 32 0 .01 - < 0.01 1.00E00 1.00E00 N-terminal protein myristoylation (GO:0006499) 4 0 .00 - < 0.01 1.00E00 1.00E00 multi-organism reproductive process (GO:0044703) 196 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of erythrocyte apoptotic process (GO:1902251) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal protein lipidation (GO:0006498) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of erythrocyte apoptotic process (GO:1902250) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein lipidation (GO:0006497) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-16 production (GO:0032739) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-15 production (GO:0032738) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein O-linked glycosylation (GO:0006493) 97 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-13 production (GO:0032736) 14 0 .00 - < 0.01 1.00E00 1.00E00 N-glycan processing (GO:0006491) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-12 production (GO:0032735) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-10 production (GO:0032733) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell extravasation (GO:2000409) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-1 production (GO:0032732) 72 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of T cell extravasation (GO:2000408) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-1 beta production (GO:0032731) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of T cell extravasation (GO:2000407) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-1 alpha production (GO:0032730) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell migration (GO:2000406) 37 0 .01 - < 0.01 1.00E00 1.00E00 ligand-independent adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0038035) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell migration (GO:2000405) 7 0 .00 - < 0.01 1.00E00 1.00E00 signal transduction in absence of ligand (GO:0038034) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of T cell migration (GO:2000404) 52 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway (GO:0038033) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte migration (GO:2000403) 44 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte migration (GO:2000402) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte migration (GO:2000401) 71 0 .02 - < 0.01 1.00E00 1.00E00 geranylgeranyl diphosphate catabolic process (GO:1902247) 1 0 .00 - < 0.01 1.00E00 1.00E00 dolichyl diphosphate biosynthetic process (GO:0006489) 5 0 .00 - < 0.01 1.00E00 1.00E00 dolichol-linked oligosaccharide biosynthetic process (GO:0006488) 22 0 .01 - < 0.01 1.00E00 1.00E00 protein N-linked glycosylation (GO:0006487) 74 0 .02 - < 0.01 1.00E00 1.00E00 protein glycosylation (GO:0006486) 215 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of type II interferon production (GO:0032729) 77 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of interferon-beta production (GO:0032728) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of interferon-alpha production (GO:0032727) 25 0 .01 - < 0.01 1.00E00 1.00E00 protein demethylation (GO:0006482) 3 0 .00 - < 0.01 1.00E00 1.00E00 C-terminal protein methylation (GO:0006481) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) 14 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid methylation (GO:0006480) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fractalkine production (GO:0032724) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of connective tissue growth factor production (GO:0032723) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine production (GO:0032722) 72 0 .02 - < 0.01 1.00E00 1.00E00 apolipoprotein A-I-mediated signaling pathway (GO:0038027) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tumor necrosis factor production (GO:0032720) 64 0 .02 - < 0.01 1.00E00 1.00E00 reelin-mediated signaling pathway (GO:0038026) 12 0 .00 - < 0.01 1.00E00 1.00E00 insulin receptor recycling (GO:0038020) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (GO:1902239) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (GO:1902238) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902237) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902236) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of positive thymic T cell selection (GO:1902233) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of positive thymic T cell selection (GO:1902232) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein methylation (GO:0006479) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902231) 7 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine sulfation (GO:0006478) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902230) 30 0 .01 - < 0.01 1.00E00 1.00E00 protein sulfation (GO:0006477) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein deacetylation (GO:0006476) 14 0 .00 - < 0.01 1.00E00 1.00E00 internal protein amino acid acetylation (GO:0006475) 10 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid acetylation (GO:0006474) 12 0 .00 - < 0.01 1.00E00 1.00E00 protein acetylation (GO:0006473) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-8 production (GO:0032717) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-6 production (GO:0032715) 48 0 .01 - < 0.01 1.00E00 1.00E00 protein dephosphorylation (GO:0006470) 93 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-5 production (GO:0032714) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-4 production (GO:0032713) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-3 production (GO:0032712) 1 0 .00 - < 0.01 1.00E00 1.00E00 Wnt receptor catabolic process (GO:0038018) 2 0 .00 - < 0.01 1.00E00 1.00E00 insulin receptor internalization (GO:0038016) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to laminar fluid shear stress (GO:0071499) 17 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to fluid shear stress (GO:0071498) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to DNA damage (GO:1902229) 38 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to external stimulus (GO:0071496) 79 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage colony-stimulating factor signaling pathway (GO:1902228) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to endogenous stimulus (GO:0071495) 955 0 .28 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage colony-stimulating factor signaling pathway (GO:1902227) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to UV-C (GO:0071494) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage colony-stimulating factor signaling pathway (GO:1902226) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to UV-B (GO:0071493) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of acrosome reaction (GO:1902225) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to UV-A (GO:0071492) 11 0 .00 - < 0.01 1.00E00 1.00E00 ketone body metabolic process (GO:1902224) 10 0 .00 - < 0.01 1.00E00 1.00E00 erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process (GO:1902223) 3 0 .00 - < 0.01 1.00E00 1.00E00 erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein kinase activity (GO:0006469) 113 0 .03 - < 0.01 1.00E00 1.00E00 erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) 28 0 .01 - < 0.01 1.00E00 1.00E00 protein phosphorylation (GO:0006468) 378 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902220) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to amine (GO:0014075) 55 0 .02 - < 0.01 1.00E00 1.00E00 signal peptide processing (GO:0006465) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to purine-containing compound (GO:0014074) 151 0 .04 - < 0.01 1.00E00 1.00E00 steroid hormone receptor complex assembly (GO:0006463) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to isoquinoline alkaloid (GO:0014072) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-23 production (GO:0032707) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-2 production (GO:0032703) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of signal transduction by receptor internalization (GO:0038009) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-18 production (GO:0032701) 4 0 .00 - < 0.01 1.00E00 1.00E00 netrin-activated signaling pathway (GO:0038007) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-17 production (GO:0032700) 15 0 .00 - < 0.01 1.00E00 1.00E00 epidermal growth factor receptor ligand maturation (GO:0038004) 2 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled opioid receptor signaling pathway (GO:0038003) 9 0 .00 - < 0.01 1.00E00 1.00E00 paracrine signaling (GO:0038001) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902219) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to high light intensity (GO:0071486) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to osmotic stress (GO:1902218) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to absence of light (GO:0071485) 2 0 .00 - < 0.01 1.00E00 1.00E00 erythrocyte apoptotic process (GO:1902217) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to light intensity (GO:0071484) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-4-mediated signaling pathway (GO:1902216) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to blue light (GO:0071483) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-4-mediated signaling pathway (GO:1902215) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to light stimulus (GO:0071482) 112 0 .03 - < 0.01 1.00E00 1.00E00 regulation of interleukin-4-mediated signaling pathway (GO:1902214) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to X-ray (GO:0071481) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to gamma radiation (GO:0071480) 28 0 .01 - < 0.01 1.00E00 1.00E00 'de novo' protein folding (GO:0006458) 48 0 .01 - < 0.01 1.00E00 1.00E00 protein folding (GO:0006457) 227 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of serotonin secretion (GO:0014064) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of serotonin secretion (GO:0014063) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of serotonin secretion (GO:0014062) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of norepinephrine secretion (GO:0014061) 14 0 .00 - < 0.01 1.00E00 1.00E00 translational readthrough (GO:0006451) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epinephrine secretion (GO:0014060) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational fidelity (GO:0006450) 18 0 .01 - < 0.01 1.00E00 1.00E00 tRNA wobble uridine modification (GO:0002098) 17 0 .00 - < 0.01 1.00E00 1.00E00 tRNA wobble base modification (GO:0002097) 21 0 .01 - < 0.01 1.00E00 1.00E00 auditory receptor cell morphogenesis (GO:0002093) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of receptor internalization (GO:0002092) 29 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of receptor internalization (GO:0002091) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor internalization (GO:0002090) 75 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to ionizing radiation (GO:0071479) 72 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to radiation (GO:0071478) 172 0 .05 - < 0.01 1.00E00 1.00E00 cellular hypotonic salinity response (GO:0071477) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular hypotonic response (GO:0071476) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular hyperosmotic salinity response (GO:0071475) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular hyperosmotic response (GO:0071474) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-2-mediated signaling pathway (GO:1902206) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-2-mediated signaling pathway (GO:1902205) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to salt stress (GO:0071472) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte growth factor receptor signaling pathway (GO:1902204) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to non-ionic osmotic stress (GO:0071471) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte growth factor receptor signaling pathway (GO:1902203) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dopamine secretion (GO:0014059) 24 0 .01 - < 0.01 1.00E00 1.00E00 C-terminal protein amino acid modification (GO:0018410) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to osmotic stress (GO:0071470) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte growth factor receptor signaling pathway (GO:1902202) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational termination (GO:0006449) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational elongation (GO:0006448) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of acetylcholine secretion, neurotransmission (GO:0014057) 3 0 .00 - < 0.01 1.00E00 1.00E00 membrane depolarization (GO:0051899) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by iron (GO:0006447) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acetylcholine secretion, neurotransmission (GO:0014056) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (GO:0051898) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of translational initiation (GO:0006446) 84 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (GO:0051897) 193 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of gamma-aminobutyric acid secretion (GO:0014054) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction (GO:0051896) 269 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of gamma-aminobutyric acid secretion (GO:0014053) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of focal adhesion assembly (GO:0051895) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gamma-aminobutyric acid secretion (GO:0014052) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of focal adhesion assembly (GO:0051894) 26 0 .01 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid secretion (GO:0014051) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of focal adhesion assembly (GO:0051893) 63 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of glutamate secretion (GO:0014050) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardioblast differentiation (GO:0051892) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glial cell derived neurotrophic factor (GO:1990792) 2 0 .00 - < 0.01 1.00E00 1.00E00 lens morphogenesis in camera-type eye (GO:0002089) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardioblast differentiation (GO:0051891) 4 0 .00 - < 0.01 1.00E00 1.00E00 dorsal root ganglion development (GO:1990791) 7 0 .00 - < 0.01 1.00E00 1.00E00 lens development in camera-type eye (GO:0002088) 84 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cardioblast differentiation (GO:0051890) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to glial cell derived neurotrophic factor (GO:1990790) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of respiratory gaseous exchange by nervous system process (GO:0002087) 13 0 .00 - < 0.01 1.00E00 1.00E00 diaphragm contraction (GO:0002086) 2 0 .00 - < 0.01 1.00E00 1.00E00 inhibition of neuroepithelial cell differentiation (GO:0002085) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein depalmitoylation (GO:0002084) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oxidative phosphorylation (GO:0002082) 22 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to alkaline pH (GO:0071469) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to acidic pH (GO:0071468) 17 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to pH (GO:0071467) 27 0 .01 - < 0.01 1.00E00 1.00E00 protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan (GO:0018406) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to xenobiotic stimulus (GO:0071466) 203 0 .06 - < 0.01 1.00E00 1.00E00 cellular response to hydrostatic pressure (GO:0071464) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to water stimulus (GO:0071462) 6 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-proline hydroxylation to 4-hydroxy-L-proline (GO:0018401) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to redox state (GO:0071461) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate secretion (GO:0014049) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cell-matrix adhesion (GO:0071460) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamate secretion (GO:0014048) 18 0 .01 - < 0.01 1.00E00 1.00E00 valyl-tRNA aminoacylation (GO:0006438) 2 0 .00 - < 0.01 1.00E00 1.00E00 glutamate secretion (GO:0014047) 14 0 .00 - < 0.01 1.00E00 1.00E00 tyrosyl-tRNA aminoacylation (GO:0006437) 2 0 .00 - < 0.01 1.00E00 1.00E00 dopamine secretion (GO:0014046) 6 0 .00 - < 0.01 1.00E00 1.00E00 tryptophanyl-tRNA aminoacylation (GO:0006436) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of endothelial blood-brain barrier (GO:0014045) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hh target transcription factor activity (GO:1990787) 1 0 .00 - < 0.01 1.00E00 1.00E00 threonyl-tRNA aminoacylation (GO:0006435) 3 0 .00 - < 0.01 1.00E00 1.00E00 Schwann cell development (GO:0014044) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of timing of anagen (GO:0051886) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to dsDNA (GO:1990786) 2 0 .00 - < 0.01 1.00E00 1.00E00 seryl-tRNA aminoacylation (GO:0006434) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron maturation (GO:0014043) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of timing of anagen (GO:0051885) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to water-immersion restraint stress (GO:1990785) 3 0 .00 - < 0.01 1.00E00 1.00E00 prolyl-tRNA aminoacylation (GO:0006433) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuron maturation (GO:0014042) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of timing of anagen (GO:0051884) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to dsDNA (GO:1990784) 2 0 .00 - < 0.01 1.00E00 1.00E00 phenylalanyl-tRNA aminoacylation (GO:0006432) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron maturation (GO:0014041) 8 0 .00 - < 0.01 1.00E00 1.00E00 methionyl-tRNA aminoacylation (GO:0006431) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell differentiation (GO:0014040) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial depolarization (GO:0051882) 7 0 .00 - < 0.01 1.00E00 1.00E00 lysyl-tRNA aminoacylation (GO:0006430) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial membrane potential (GO:0051881) 75 0 .02 - < 0.01 1.00E00 1.00E00 acrosome matrix dispersal (GO:0002077) 1 0 .00 - < 0.01 1.00E00 1.00E00 osteoblast development (GO:0002076) 17 0 .00 - < 0.01 1.00E00 1.00E00 extraocular skeletal muscle development (GO:0002074) 5 0 .00 - < 0.01 1.00E00 1.00E00 optic cup morphogenesis involved in camera-type eye development (GO:0002072) 7 0 .00 - < 0.01 1.00E00 1.00E00 glandular epithelial cell maturation (GO:0002071) 6 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell maturation (GO:0002070) 28 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to chromosome, centromeric region (GO:0071459) 25 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to hypoxia (GO:0071456) 129 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to hyperoxia (GO:0071455) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to anoxia (GO:0071454) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oxygen levels (GO:0071453) 153 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to superoxide (GO:0071451) 18 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to oxygen radical (GO:0071450) 18 0 .01 - < 0.01 1.00E00 1.00E00 leucyl-tRNA aminoacylation (GO:0006429) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell differentiation (GO:0014038) 4 0 .00 - < 0.01 1.00E00 1.00E00 isoleucyl-tRNA aminoacylation (GO:0006428) 2 0 .00 - < 0.01 1.00E00 1.00E00 Schwann cell differentiation (GO:0014037) 48 0 .01 - < 0.01 1.00E00 1.00E00 histidyl-tRNA aminoacylation (GO:0006427) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell fate specification (GO:0014036) 2 0 .00 - < 0.01 1.00E00 1.00E00 lateral element assembly (GO:0051878) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell periphery (GO:1990778) 235 0 .07 - < 0.01 1.00E00 1.00E00 glycyl-tRNA aminoacylation (GO:0006426) 1 0 .00 - < 0.01 1.00E00 1.00E00 pigment granule aggregation in cell center (GO:0051877) 2 0 .00 - < 0.01 1.00E00 1.00E00 glutaminyl-tRNA aminoacylation (GO:0006425) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell fate commitment (GO:0014034) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to angiotensin (GO:1990776) 42 0 .01 - < 0.01 1.00E00 1.00E00 glutamyl-tRNA aminoacylation (GO:0006424) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell differentiation (GO:0014033) 92 0 .03 - < 0.01 1.00E00 1.00E00 pigment granule localization (GO:0051875) 24 0 .01 - < 0.01 1.00E00 1.00E00 cysteinyl-tRNA aminoacylation (GO:0006423) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell development (GO:0014032) 79 0 .02 - < 0.01 1.00E00 1.00E00 aspartyl-tRNA aminoacylation (GO:0006422) 2 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell development (GO:0014031) 6 0 .00 - < 0.01 1.00E00 1.00E00 killing by host of symbiont cells (GO:0051873) 29 0 .01 - < 0.01 1.00E00 1.00E00 asparaginyl-tRNA aminoacylation (GO:0006421) 3 0 .00 - < 0.01 1.00E00 1.00E00 columnar/cuboidal epithelial cell maturation (GO:0002069) 12 0 .00 - < 0.01 1.00E00 1.00E00 arginyl-tRNA aminoacylation (GO:0006420) 3 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-dependent extracellular exosome endocytosis (GO:1990771) 1 0 .00 - < 0.01 1.00E00 1.00E00 glandular epithelial cell development (GO:0002068) 12 0 .00 - < 0.01 1.00E00 1.00E00 small intestine smooth muscle contraction (GO:1990770) 1 0 .00 - < 0.01 1.00E00 1.00E00 glandular epithelial cell differentiation (GO:0002067) 36 0 .01 - < 0.01 1.00E00 1.00E00 columnar/cuboidal epithelial cell development (GO:0002066) 28 0 .01 - < 0.01 1.00E00 1.00E00 columnar/cuboidal epithelial cell differentiation (GO:0002065) 104 0 .03 - < 0.01 1.00E00 1.00E00 epithelial cell development (GO:0002064) 197 0 .06 - < 0.01 1.00E00 1.00E00 chondrocyte development (GO:0002063) 28 0 .01 - < 0.01 1.00E00 1.00E00 chondrocyte differentiation (GO:0002062) 85 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to lipid hydroperoxide (GO:0071449) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to alkyl hydroperoxide (GO:0071448) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hydroperoxide (GO:0071447) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to pheromone (GO:0071444) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural crest formation (GO:0014029) 14 0 .00 - < 0.01 1.00E00 1.00E00 alanyl-tRNA aminoacylation (GO:0006419) 3 0 .00 - < 0.01 1.00E00 1.00E00 notochord formation (GO:0014028) 3 0 .00 - < 0.01 1.00E00 1.00E00 tRNA aminoacylation for protein translation (GO:0006418) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of translation (GO:0006417) 367 0 .11 - < 0.01 1.00E00 1.00E00 general adaptation syndrome, behavioral process (GO:0051867) 5 0 .00 - < 0.01 1.00E00 1.00E00 translational termination (GO:0006415) 11 0 .00 - < 0.01 1.00E00 1.00E00 general adaptation syndrome (GO:0051866) 6 0 .00 - < 0.01 1.00E00 1.00E00 translational elongation (GO:0006414) 63 0 .02 - < 0.01 1.00E00 1.00E00 protein autoubiquitination (GO:0051865) 70 0 .02 - < 0.01 1.00E00 1.00E00 translational initiation (GO:0006413) 69 0 .02 - < 0.01 1.00E00 1.00E00 neural plate elongation (GO:0014022) 2 0 .00 - < 0.01 1.00E00 1.00E00 myofibroblast contraction (GO:1990764) 2 0 .00 - < 0.01 1.00E00 1.00E00 translation (GO:0006412) 392 0 .11 - < 0.01 1.00E00 1.00E00 primary neural tube formation (GO:0014020) 92 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal cell proliferation (GO:0002053) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of neuroblast proliferation (GO:0002052) 29 0 .01 - < 0.01 1.00E00 1.00E00 osteoblast fate commitment (GO:0002051) 3 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of epithelial cell apical/basal polarity (GO:0045199) 7 0 .00 - < 0.01 1.00E00 1.00E00 establishment of epithelial cell apical/basal polarity (GO:0045198) 17 0 .00 - < 0.01 1.00E00 1.00E00 establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) 49 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of neuroblast polarity (GO:0045196) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of isotype switching (GO:0045191) 38 0 .01 - < 0.01 1.00E00 1.00E00 isotype switching (GO:0045190) 25 0 .01 - < 0.01 1.00E00 1.00E00 tRNA export from nucleus (GO:0006409) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of proteasomal protein catabolic process (GO:1901799) 54 0 .02 - < 0.01 1.00E00 1.00E00 snRNA export from nucleus (GO:0006408) 4 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast fate commitment (GO:0014017) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of signal transduction by p53 class mediator (GO:1901798) 31 0 .01 - < 0.01 1.00E00 1.00E00 neuroblast differentiation (GO:0014016) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of signal transduction by p53 class mediator (GO:1901797) 36 0 .01 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid biorientation (GO:1990758) 2 0 .00 - < 0.01 1.00E00 1.00E00 mRNA export from nucleus (GO:0006406) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of gliogenesis (GO:0014015) 69 0 .02 - < 0.01 1.00E00 1.00E00 regulation of signal transduction by p53 class mediator (GO:1901796) 110 0 .03 - < 0.01 1.00E00 1.00E00 RNA export from nucleus (GO:0006405) 84 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of gliogenesis (GO:0014014) 43 0 .01 - < 0.01 1.00E00 1.00E00 RNA import into nucleus (GO:0006404) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gliogenesis (GO:0014013) 105 0 .03 - < 0.01 1.00E00 1.00E00 mitotic spindle microtubule depolymerization (GO:1990755) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA localization (GO:0006403) 190 0 .06 - < 0.01 1.00E00 1.00E00 peripheral nervous system axon regeneration (GO:0014012) 7 0 .00 - < 0.01 1.00E00 1.00E00 mRNA catabolic process (GO:0006402) 125 0 .04 - < 0.01 1.00E00 1.00E00 RNA catabolic process (GO:0006401) 170 0 .05 - < 0.01 1.00E00 1.00E00 Schwann cell proliferation (GO:0014010) 3 0 .00 - < 0.01 1.00E00 1.00E00 tRNA modification (GO:0006400) 92 0 .03 - < 0.01 1.00E00 1.00E00 host-mediated perturbation of symbiont process (GO:0051851) 107 0 .03 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:0002043) 7 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in sprouting angiogenesis (GO:0002042) 26 0 .01 - < 0.01 1.00E00 1.00E00 intussusceptive angiogenesis (GO:0002041) 1 0 .00 - < 0.01 1.00E00 1.00E00 sprouting angiogenesis (GO:0002040) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, non-REM sleep (GO:0045188) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, sleep (GO:0045187) 15 0 .00 - < 0.01 1.00E00 1.00E00 zonula adherens assembly (GO:0045186) 2 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein location (GO:0045185) 67 0 .02 - < 0.01 1.00E00 1.00E00 establishment of protein localization (GO:0045184) 1307 0 .38 - < 0.01 1.00E00 1.00E00 hematopoietic stem cell proliferation (GO:0071425) 25 0 .01 - < 0.01 1.00E00 1.00E00 malate transmembrane transport (GO:0071423) 3 0 .00 - < 0.01 1.00E00 1.00E00 succinate transmembrane transport (GO:0071422) 5 0 .00 - < 0.01 1.00E00 1.00E00 manganese ion transmembrane transport (GO:0071421) 10 0 .00 - < 0.01 1.00E00 1.00E00 glial cell proliferation (GO:0014009) 29 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to histamine (GO:0071420) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microglia differentiation (GO:0014008) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microglia differentiation (GO:0014006) 1 0 .00 - < 0.01 1.00E00 1.00E00 benzoyl-CoA metabolic process (GO:1901787) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular detoxification (GO:1990748) 117 0 .03 - < 0.01 1.00E00 1.00E00 microglia development (GO:0014005) 4 0 .00 - < 0.01 1.00E00 1.00E00 microglia differentiation (GO:0014004) 15 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte development (GO:0014003) 49 0 .01 - < 0.01 1.00E00 1.00E00 astrocyte development (GO:0014002) 37 0 .01 - < 0.01 1.00E00 1.00E00 protein sialylation (GO:1990743) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of L-glutamate import across plasma membrane (GO:0002038) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of L-glutamate import across plasma membrane (GO:0002037) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of L-glutamate import across plasma membrane (GO:0002036) 9 0 .00 - < 0.01 1.00E00 1.00E00 brain renin-angiotensin system (GO:0002035) 3 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of blood vessel diameter homeostasis by renin-angiotensin (GO:0002034) 7 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0002033) 3 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor internalization (GO:0002031) 9 0 .00 - < 0.01 1.00E00 1.00E00 apical protein localization (GO:0045176) 15 0 .00 - < 0.01 1.00E00 1.00E00 basal protein localization (GO:0045175) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to amine stimulus (GO:0071418) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to purine-containing compound (GO:0071415) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hydroxyisoflavone (GO:0071413) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to genistein (GO:0071412) 1 0 .00 - < 0.01 1.00E00 1.00E00 granulosa cell proliferation (GO:1990739) 1 0 .00 - < 0.01 1.00E00 1.00E00 cytolysis by host of symbiont cells (GO:0051838) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to manganese-induced endoplasmic reticulum stress (GO:1990737) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synapse structural plasticity (GO:0051835) 4 0 .00 - < 0.01 1.00E00 1.00E00 desensitization of G protein-coupled receptor signaling pathway (GO:0002029) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sodium ion transport (GO:0002028) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of heart rate (GO:0002027) 104 0 .03 - < 0.01 1.00E00 1.00E00 regulation of the force of heart contraction (GO:0002026) 26 0 .01 - < 0.01 1.00E00 1.00E00 norepinephrine-epinephrine-mediated vasodilation involved in regulation of systemic arterial blood pressure (GO:0002025) 3 0 .00 - < 0.01 1.00E00 1.00E00 diet induced thermogenesis (GO:0002024) 13 0 .00 - < 0.01 1.00E00 1.00E00 reduction of food intake in response to dietary excess (GO:0002023) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to dietary excess (GO:0002021) 37 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in cell fate commitment (GO:0045168) 3 0 .00 - < 0.01 1.00E00 1.00E00 asymmetric protein localization involved in cell fate determination (GO:0045167) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell fate commitment (GO:0045165) 255 0 .07 - < 0.01 1.00E00 1.00E00 cellular response to cycloheximide (GO:0071409) 2 0 .00 - < 0.01 1.00E00 1.00E00 clustering of voltage-gated potassium channels (GO:0045163) 4 0 .00 - < 0.01 1.00E00 1.00E00 clustering of voltage-gated sodium channels (GO:0045162) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuronal ion channel clustering (GO:0045161) 12 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to low-density lipoprotein particle stimulus (GO:0071404) 31 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to high density lipoprotein particle stimulus (GO:0071403) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to ATP (GO:0033198) 33 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to lipoprotein particle stimulus (GO:0071402) 38 0 .01 - < 0.01 1.00E00 1.00E00 response to vitamin E (GO:0033197) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to triglyceride (GO:0071401) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oleic acid (GO:0071400) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to alkyl hydroperoxide (GO:0033195) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to hydroperoxide (GO:0033194) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of synapse structural plasticity (GO:0051823) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renal output by angiotensin (GO:0002019) 2 0 .00 - < 0.01 1.00E00 1.00E00 renin-angiotensin regulation of aldosterone production (GO:0002018) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood volume by renal aldosterone (GO:0002017) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood volume by renin-angiotensin (GO:0002016) 7 0 .00 - < 0.01 1.00E00 1.00E00 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure (GO:0002014) 1 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of an epithelial sheet (GO:0002011) 53 0 .02 - < 0.01 1.00E00 1.00E00 response to vitamin A (GO:0033189) 16 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene A4 biosynthetic process (GO:1901753) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene A4 metabolic process (GO:1901751) 2 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of an epithelium (GO:0002009) 458 0 .13 - < 0.01 1.00E00 1.00E00 xylulose catabolic process (GO:0005998) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene D4 biosynthetic process (GO:1901750) 10 0 .00 - < 0.01 1.00E00 1.00E00 xylulose metabolic process (GO:0005997) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of hypoxic conditions in blood by chemoreceptor signaling (GO:0002007) 2 0 .00 - < 0.01 1.00E00 1.00E00 monosaccharide metabolic process (GO:0005996) 186 1 .05 + 18.44 5.30E-02 1.00E00 trehalose catabolic process (GO:0005993) 1 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin maturation (GO:0002003) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of angiotensin levels in blood (GO:0002002) 14 0 .00 - < 0.01 1.00E00 1.00E00 trehalose metabolic process (GO:0005991) 1 0 .00 - < 0.01 1.00E00 1.00E00 renin secretion into blood stream (GO:0002001) 4 0 .00 - < 0.01 1.00E00 1.00E00 lactose catabolic process (GO:0005990) 1 0 .00 - < 0.01 1.00E00 1.00E00 male anatomical structure morphogenesis (GO:0090598) 4 0 .00 - < 0.01 1.00E00 1.00E00 sensory organ morphogenesis (GO:0090596) 283 0 .08 - < 0.01 1.00E00 1.00E00 homologous chromosome segregation (GO:0045143) 66 0 .02 - < 0.01 1.00E00 1.00E00 inflammatory response to wounding (GO:0090594) 14 0 .00 - < 0.01 1.00E00 1.00E00 meiotic telomere clustering (GO:0045141) 11 0 .00 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in DNA replication (GO:0090592) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene D4 catabolic process (GO:1901749) 2 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene D4 metabolic process (GO:1901748) 12 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic active zone organization (GO:1990709) 10 0 .00 - < 0.01 1.00E00 1.00E00 calcineurin-NFAT signaling cascade (GO:0033173) 19 0 .01 - < 0.01 1.00E00 1.00E00 conditioned place preference (GO:1990708) 6 0 .00 - < 0.01 1.00E00 1.00E00 cholangiocyte proliferation (GO:1990705) 2 0 .00 - < 0.01 1.00E00 1.00E00 lactose biosynthetic process (GO:0005989) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myoblast fusion (GO:1901741) 15 0 .00 - < 0.01 1.00E00 1.00E00 lactose metabolic process (GO:0005988) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myoblast fusion (GO:1901740) 3 0 .00 - < 0.01 1.00E00 1.00E00 sucrose catabolic process (GO:0005987) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleolar chromatin organization (GO:1990700) 8 0 .00 - < 0.01 1.00E00 1.00E00 sucrose metabolic process (GO:0005985) 2 0 .00 - < 0.01 1.00E00 1.00E00 disaccharide metabolic process (GO:0005984) 8 0 .00 - < 0.01 1.00E00 1.00E00 starch catabolic process (GO:0005983) 1 0 .00 - < 0.01 1.00E00 1.00E00 starch metabolic process (GO:0005982) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glycogen catabolic process (GO:0005981) 7 0 .00 - < 0.01 1.00E00 1.00E00 glycogen catabolic process (GO:0005980) 20 0 .01 - < 0.01 1.00E00 1.00E00 development of primary sexual characteristics (GO:0045137) 237 1 .07 + 14.47 6.71E-02 1.00E00 development of secondary sexual characteristics (GO:0045136) 10 0 .00 - < 0.01 1.00E00 1.00E00 meiotic chromosome segregation (GO:0045132) 92 0 .03 - < 0.01 1.00E00 1.00E00 regulation of myoblast fusion (GO:1901739) 20 0 .01 - < 0.01 1.00E00 1.00E00 quercetin catabolic process (GO:1901733) 1 0 .00 - < 0.01 1.00E00 1.00E00 quercetin metabolic process (GO:1901732) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glycogen biosynthetic process (GO:0005979) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of platelet aggregation (GO:1901731) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycogen biosynthetic process (GO:0005978) 19 0 .01 - < 0.01 1.00E00 1.00E00 glycogen metabolic process (GO:0005977) 61 0 .02 - < 0.01 1.00E00 1.00E00 polysaccharide metabolic process (GO:0005976) 83 0 .02 - < 0.01 1.00E00 1.00E00 carbohydrate metabolic process (GO:0005975) 447 1 .13 + 7.67 1.23E-01 1.00E00 regulation of bone resorption (GO:0045124) 45 0 .01 - < 0.01 1.00E00 1.00E00 cellular extravasation (GO:0045123) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of intracellular protein transport (GO:0033157) 152 0 .04 - < 0.01 1.00E00 1.00E00 T cell receptor V(D)J recombination (GO:0033153) 4 0 .00 - < 0.01 1.00E00 1.00E00 NADPH oxidation (GO:0070995) 7 0 .00 - < 0.01 1.00E00 1.00E00 immunoglobulin V(D)J recombination (GO:0033152) 8 0 .00 - < 0.01 1.00E00 1.00E00 detection of oxidative stress (GO:0070994) 2 0 .00 - < 0.01 1.00E00 1.00E00 V(D)J recombination (GO:0033151) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in kidney development (GO:1901724) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in kidney development (GO:1901723) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in kidney development (GO:1901722) 14 0 .00 - < 0.01 1.00E00 1.00E00 azole transmembrane transport (GO:0045117) 15 0 .00 - < 0.01 1.00E00 1.00E00 protein neddylation (GO:0045116) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of integrin biosynthetic process (GO:0045113) 4 0 .00 - < 0.01 1.00E00 1.00E00 integrin biosynthetic process (GO:0045112) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermediate filament bundle assembly (GO:0045110) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular estrogen receptor signaling pathway (GO:0033148) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147) 15 0 .00 - < 0.01 1.00E00 1.00E00 oxidative demethylation (GO:0070989) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular estrogen receptor signaling pathway (GO:0033146) 37 0 .01 - < 0.01 1.00E00 1.00E00 demethylation (GO:0070988) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) 14 0 .00 - < 0.01 1.00E00 1.00E00 error-free translesion synthesis (GO:0070987) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular steroid hormone receptor signaling pathway (GO:0033144) 37 0 .01 - < 0.01 1.00E00 1.00E00 left/right axis specification (GO:0070986) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular steroid hormone receptor signaling pathway (GO:0033143) 75 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033141) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033140) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-asparagine metabolic process (GO:0070982) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-asparagine biosynthetic process (GO:0070981) 1 0 .00 - < 0.01 1.00E00 1.00E00 biphenyl catabolic process (GO:0070980) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermediate filament organization (GO:0045109) 76 0 .02 - < 0.01 1.00E00 1.00E00 regulation of intermediate filament polymerization or depolymerization (GO:0045108) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane permeability (GO:0090559) 69 0 .02 - < 0.01 1.00E00 1.00E00 intermediate filament polymerization (GO:0045107) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of endothelial intestinal barrier (GO:0090557) 11 0 .00 - < 0.01 1.00E00 1.00E00 intermediate filament polymerization or depolymerization (GO:0045105) 2 0 .00 - < 0.01 1.00E00 1.00E00 intermediate filament cytoskeleton organization (GO:0045104) 96 0 .03 - < 0.01 1.00E00 1.00E00 intermediate filament-based process (GO:0045103) 97 0 .03 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-serine phosphorylation of STAT protein (GO:0033139) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-serine phosphorylation (GO:0033138) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-serine phosphorylation (GO:0033137) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein K11-linked ubiquitination (GO:0070979) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-serine phosphorylation (GO:0033135) 42 0 .01 - < 0.01 1.00E00 1.00E00 bone maturation (GO:0070977) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glucokinase activity (GO:0033132) 3 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in bone development (GO:1901706) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to endoplasmic reticulum exit site (GO:0070973) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to endoplasmic reticulum (GO:0070972) 68 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to oxygen-containing compound (GO:1901701) 1083 0 .32 - < 0.01 1.00E00 1.00E00 response to oxygen-containing compound (GO:1901700) 1592 2 .46 + 4.31 7.28E-02 1.00E00 detection of chemical stimulus involved in sensory perception of sweet taste (GO:0001582) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of sour taste (GO:0001581) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) 38 0 .01 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, no-go decay (GO:0070966) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of purine nucleotide catabolic process (GO:0033123) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of fungus (GO:0070965) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of purine nucleotide catabolic process (GO:0033122) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of purine nucleotide catabolic process (GO:0033121) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of gram-negative bacterium (GO:0070963) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of RNA splicing (GO:0033120) 47 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of bacterium (GO:0070962) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated killing of symbiont cell (GO:0070961) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil mediated cytotoxicity (GO:0070960) 3 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid transport (GO:0001579) 2 0 .00 - < 0.01 1.00E00 1.00E00 microtubule bundle formation (GO:0001578) 135 0 .04 - < 0.01 1.00E00 1.00E00 globoside biosynthetic process (GO:0001576) 2 0 .00 - < 0.01 1.00E00 1.00E00 globoside metabolic process (GO:0001575) 2 0 .00 - < 0.01 1.00E00 1.00E00 ganglioside biosynthetic process (GO:0001574) 17 0 .00 - < 0.01 1.00E00 1.00E00 ganglioside metabolic process (GO:0001573) 29 0 .01 - < 0.01 1.00E00 1.00E00 lactosylceramide biosynthetic process (GO:0001572) 2 0 .00 - < 0.01 1.00E00 1.00E00 vasculogenesis (GO:0001570) 72 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of RNA splicing (GO:0033119) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of fungus (GO:0070953) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of gram-negative bacterium (GO:0070951) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of bacterium (GO:0070950) 2 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in blood vessel morphogenesis (GO:0001569) 30 0 .01 - < 0.01 1.00E00 1.00E00 blood vessel development (GO:0001568) 536 0 .16 - < 0.01 1.00E00 1.00E00 antiviral innate immune response (GO:0140374) 65 0 .02 - < 0.01 1.00E00 1.00E00 response to protozoan (GO:0001562) 30 0 .01 - < 0.01 1.00E00 1.00E00 fatty acid alpha-oxidation (GO:0001561) 7 0 .00 - < 0.01 1.00E00 1.00E00 vesicle tethering involved in exocytosis (GO:0090522) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell growth by extracellular stimulus (GO:0001560) 3 0 .00 - < 0.01 1.00E00 1.00E00 podocyte cell migration (GO:0090521) 7 0 .00 - < 0.01 1.00E00 1.00E00 sphingolipid mediated signaling pathway (GO:0090520) 17 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex assembly (GO:0033108) 102 0 .03 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated killing of symbiont cell (GO:0070949) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil mediated cytotoxicity (GO:0070948) 6 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil-mediated killing of fungus (GO:0070947) 1 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil-mediated killing of gram-positive bacterium (GO:0070946) 2 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil-mediated killing of gram-negative bacterium (GO:0070945) 5 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil-mediated killing of bacterium (GO:0070944) 11 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil-mediated killing of symbiont cell (GO:0070943) 11 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil mediated cytotoxicity (GO:0070942) 11 0 .00 - < 0.01 1.00E00 1.00E00 antibacterial innate immune response (GO:0140367) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell growth (GO:0001558) 401 0 .12 - < 0.01 1.00E00 1.00E00 oocyte maturation (GO:0001556) 28 0 .01 - < 0.01 1.00E00 1.00E00 oocyte growth (GO:0001555) 4 0 .00 - < 0.01 1.00E00 1.00E00 luteolysis (GO:0001554) 8 0 .00 - < 0.01 1.00E00 1.00E00 cyclic-GMP-AMP transmembrane import across plasma membrane (GO:0140361) 7 0 .00 - < 0.01 1.00E00 1.00E00 luteinization (GO:0001553) 10 0 .00 - < 0.01 1.00E00 1.00E00 ovarian follicle atresia (GO:0001552) 1 0 .00 - < 0.01 1.00E00 1.00E00 ovarian cumulus expansion (GO:0001550) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein K48-linked ubiquitination (GO:0070936) 95 0 .03 - < 0.01 1.00E00 1.00E00 tooth eruption (GO:0044691) 6 0 .00 - < 0.01 1.00E00 1.00E00 3'-UTR-mediated mRNA stabilization (GO:0070935) 22 0 .01 - < 0.01 1.00E00 1.00E00 CRD-mediated mRNA stabilization (GO:0070934) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin-dependent endocytosis (GO:2000397) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-dependent endocytosis (GO:2000395) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lamellipodium morphogenesis (GO:2000394) 7 0 .00 - < 0.01 1.00E00 1.00E00 heme export from vacuole to cytoplasm (GO:0140357) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium morphogenesis (GO:2000393) 2 0 .00 - < 0.01 1.00E00 1.00E00 cumulus cell differentiation (GO:0001549) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lamellipodium morphogenesis (GO:2000392) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil extravasation (GO:2000391) 7 0 .00 - < 0.01 1.00E00 1.00E00 antral ovarian follicle growth (GO:0001547) 11 0 .00 - < 0.01 1.00E00 1.00E00 lipid import into cell (GO:0140354) 14 0 .00 - < 0.01 1.00E00 1.00E00 preantral ovarian follicle growth (GO:0001546) 3 0 .00 - < 0.01 1.00E00 1.00E00 lipid export from cell (GO:0140353) 13 0 .00 - < 0.01 1.00E00 1.00E00 primary ovarian follicle growth (GO:0001545) 1 0 .00 - < 0.01 1.00E00 1.00E00 export from cell (GO:0140352) 498 0 .15 - < 0.01 1.00E00 1.00E00 initiation of primordial ovarian follicle growth (GO:0001544) 2 0 .00 - < 0.01 1.00E00 1.00E00 epiboly involved in wound healing (GO:0090505) 30 0 .01 - < 0.01 1.00E00 1.00E00 ovarian follicle rupture (GO:0001543) 1 0 .00 - < 0.01 1.00E00 1.00E00 epiboly (GO:0090504) 31 0 .01 - < 0.01 1.00E00 1.00E00 ovulation from ovarian follicle (GO:0001542) 10 0 .00 - < 0.01 1.00E00 1.00E00 ovarian follicle development (GO:0001541) 57 0 .02 - < 0.01 1.00E00 1.00E00 endocardial cushion to mesenchymal transition (GO:0090500) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ATP:ADP antiporter activity (GO:0070926) 1 0 .00 - < 0.01 1.00E00 1.00E00 organelle assembly (GO:0070925) 890 0 .26 - < 0.01 1.00E00 1.00E00 RISC complex assembly (GO:0070922) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of siRNA processing (GO:0070921) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of regulatory ncRNA processing (GO:0070920) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil extravasation (GO:2000389) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antral ovarian follicle growth (GO:2000388) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antral ovarian follicle growth (GO:2000387) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ovarian follicle development (GO:2000386) 1 0 .00 - < 0.01 1.00E00 1.00E00 cilium or flagellum-dependent cell motility (GO:0001539) 198 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of mesoderm development (GO:2000382) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesoderm development (GO:2000381) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesoderm development (GO:2000380) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulatory ncRNA processing (GO:0070918) 58 0 .02 - < 0.01 1.00E00 1.00E00 UV-damage excision repair (GO:0070914) 13 0 .00 - < 0.01 1.00E00 1.00E00 global genome nucleotide-excision repair (GO:0070911) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of reactive oxygen species metabolic process (GO:2000379) 72 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of reactive oxygen species metabolic process (GO:2000378) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of reactive oxygen species metabolic process (GO:2000377) 144 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of oxygen metabolic process (GO:2000376) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oxygen metabolic process (GO:2000374) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity (GO:2000373) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of clathrin-dependent endocytosis (GO:2000370) 3 0 .00 - < 0.01 1.00E00 1.00E00 angiogenesis (GO:0001525) 353 0 .10 - < 0.01 1.00E00 1.00E00 aminophospholipid translocation (GO:0140331) 7 0 .00 - < 0.01 1.00E00 1.00E00 retinoid metabolic process (GO:0001523) 86 1 .03 + 39.88 2.48E-02 1.00E00 pseudouridine synthesis (GO:0001522) 18 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA pseudouridine synthesis (GO:0070902) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA methylation (GO:0070901) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-13 production (GO:0032696) 7 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA modification (GO:0070900) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-12 production (GO:0032695) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-10 production (GO:0032693) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of clathrin-dependent endocytosis (GO:2000369) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-1 production (GO:0032692) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of acrosomal vesicle exocytosis (GO:2000368) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-1 beta production (GO:0032691) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of acrosomal vesicle exocytosis (GO:2000367) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-1 alpha production (GO:0032690) 2 0 .00 - < 0.01 1.00E00 1.00E00 lysophospholipid translocation (GO:0140329) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptide amidation (GO:0001519) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of binding of sperm to zona pellucida (GO:2000360) 4 0 .00 - < 0.01 1.00E00 1.00E00 prostaglandin biosynthetic process (GO:0001516) 20 0 .01 - < 0.01 1.00E00 1.00E00 selenocysteine incorporation (GO:0001514) 7 0 .00 - < 0.01 1.00E00 1.00E00 RNA methylation (GO:0001510) 82 0 .02 - < 0.01 1.00E00 1.00E00 adhesion of symbiont to host cell (GO:0044650) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type II interferon production (GO:0032689) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of interferon-beta production (GO:0032688) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interferon-alpha production (GO:0032687) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte growth factor production (GO:0032686) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte macrophage colony-stimulating factor production (GO:0032685) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue growth factor production (GO:0032683) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of binding of sperm to zona pellucida (GO:2000359) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine production (GO:0032682) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of kidney smooth muscle cell differentiation (GO:2000358) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphotoxin A production (GO:0032681) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of kidney smooth muscle cell differentiation (GO:2000357) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tumor necrosis factor production (GO:0032680) 170 0 .05 - < 0.01 1.00E00 1.00E00 regulation of kidney smooth muscle cell differentiation (GO:2000356) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ovarian follicle development (GO:2000355) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ovarian follicle development (GO:2000354) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell apoptotic process (GO:2000353) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell apoptotic process (GO:2000352) 31 0 .01 - < 0.01 1.00E00 1.00E00 action potential (GO:0001508) 129 0 .04 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell apoptotic process (GO:2000351) 55 0 .02 - < 0.01 1.00E00 1.00E00 acetylcholine catabolic process in synaptic cleft (GO:0001507) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD40 signaling pathway (GO:2000350) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter uptake (GO:0001504) 30 0 .01 - < 0.01 1.00E00 1.00E00 ossification (GO:0001503) 292 0 .09 - < 0.01 1.00E00 1.00E00 cartilage condensation (GO:0001502) 20 0 .01 - < 0.01 1.00E00 1.00E00 skeletal system development (GO:0001501) 512 1 .15 + 6.70 1.40E-01 1.00E00 regulation of TRAIL production (GO:0032679) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-8 production (GO:0032677) 85 0 .02 - < 0.01 1.00E00 1.00E00 regulation of interleukin-6 production (GO:0032675) 153 0 .04 - < 0.01 1.00E00 1.00E00 regulation of interleukin-5 production (GO:0032674) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of interleukin-4 production (GO:0032673) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of CD40 signaling pathway (GO:2000349) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-3 production (GO:0032672) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD40 signaling pathway (GO:2000348) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte proliferation (GO:2000347) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte proliferation (GO:2000346) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte proliferation (GO:2000345) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of acrosome reaction (GO:2000344) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000343) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000342) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-X-C motif) ligand 2 production (GO:2000341) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-X-C motif) ligand 1 production (GO:2000340) 5 0 .00 - < 0.01 1.00E00 1.00E00 serine import into mitochondrion (GO:0140300) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine (GO:0018395) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine acetylation (GO:0018394) 13 0 .00 - < 0.01 1.00E00 1.00E00 internal peptidyl-lysine acetylation (GO:0018393) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-23 production (GO:0032667) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-21 production (GO:0032665) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-2 production (GO:0032663) 66 0 .02 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-X-C motif) ligand 1 production (GO:2000338) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-18 production (GO:0032661) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-17 production (GO:0032660) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of blood microparticle formation (GO:2000334) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood microparticle formation (GO:2000332) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of terminal button organization (GO:2000331) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 17 cell lineage commitment (GO:2000330) 8 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor apoptotic signaling pathway (GO:1902178) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902177) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902176) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902175) 43 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of keratinocyte apoptotic process (GO:1902174) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte apoptotic process (GO:1902173) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of keratinocyte apoptotic process (GO:1902172) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to reactive nitrogen species (GO:1902170) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of interleukin-16 production (GO:0032659) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-15 production (GO:0032658) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-13 production (GO:0032656) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of interleukin-12 production (GO:0032655) 64 0 .02 - < 0.01 1.00E00 1.00E00 regulation of interleukin-10 production (GO:0032653) 61 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 cell lineage commitment (GO:2000329) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-1 production (GO:0032652) 114 0 .03 - < 0.01 1.00E00 1.00E00 regulation of T-helper 17 cell lineage commitment (GO:2000328) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-1 beta production (GO:0032651) 95 0 .03 - < 0.01 1.00E00 1.00E00 regulation of interleukin-1 alpha production (GO:0032650) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear receptor-mediated glucocorticoid signaling pathway (GO:2000324) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear receptor-mediated glucocorticoid signaling pathway (GO:2000323) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear receptor-mediated glucocorticoid signaling pathway (GO:2000322) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 17 cell differentiation (GO:2000321) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 cell differentiation (GO:2000320) 15 0 .00 - < 0.01 1.00E00 1.00E00 protein myristoylation (GO:0018377) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902167) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902166) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:1902165) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cyclic nucleotide-gated ion channel activity (GO:1902161) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type II interferon production (GO:0032649) 121 0 .04 - < 0.01 1.00E00 1.00E00 regulation of interferon-beta production (GO:0032648) 59 0 .02 - < 0.01 1.00E00 1.00E00 regulation of interferon-alpha production (GO:0032647) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte growth factor production (GO:0032646) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fractalkine production (GO:0032644) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of connective tissue growth factor production (GO:0032643) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 17 cell differentiation (GO:2000319) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of chemokine production (GO:0032642) 95 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 17 type immune response (GO:2000318) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 17 type immune response (GO:2000317) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 17 type immune response (GO:2000316) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (GO:2000314) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation (GO:2000313) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of AMPA receptor activity (GO:2000311) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NMDA receptor activity (GO:2000310) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cyclic nucleotide-gated ion channel activity (GO:1902159) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-glutamine methylation (GO:0018364) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to DNA damage checkpoint signaling (GO:1902153) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA metabolic process (GO:0006399) 199 0 .06 - < 0.01 1.00E00 1.00E00 regulation of response to DNA integrity checkpoint signaling (GO:1902151) 2 0 .00 - < 0.01 1.00E00 1.00E00 mRNA 3'-end processing by stem-loop binding and cleavage (GO:0006398) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein deadenylylation (GO:0044602) 1 0 .00 - < 0.01 1.00E00 1.00E00 mRNA processing (GO:0006397) 464 0 .14 - < 0.01 1.00E00 1.00E00 protein denucleotidylation (GO:0044601) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA processing (GO:0006396) 876 0 .26 - < 0.01 1.00E00 1.00E00 termination of mitochondrial transcription (GO:0006393) 2 0 .00 - < 0.01 1.00E00 1.00E00 transcription elongation by mitochondrial RNA polymerase (GO:0006392) 1 0 .00 - < 0.01 1.00E00 1.00E00 transcription initiation at mitochondrial promoter (GO:0006391) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial transcription (GO:0006390) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of tumor necrosis factor (ligand) superfamily member 11 production (GO:2000309) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tumor necrosis factor (ligand) superfamily member 11 production (GO:2000308) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tumor necrosis factor (ligand) superfamily member 11 production (GO:2000307) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ceramide biosynthetic process (GO:2000304) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ceramide biosynthetic process (GO:2000303) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle exocytosis (GO:2000302) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle exocytosis (GO:2000301) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle exocytosis (GO:2000300) 48 0 .01 - < 0.01 1.00E00 1.00E00 regulation of response to cell cycle checkpoint signaling (GO:1902145) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein-pyridoxal-5-phosphate linkage (GO:0018352) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to inositol (GO:1902140) 4 0 .00 - < 0.01 1.00E00 1.00E00 transcription initiation at RNA polymerase III promoter (GO:0006384) 8 0 .00 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase III (GO:0006383) 43 0 .01 - < 0.01 1.00E00 1.00E00 adenosine to inosine editing (GO:0006382) 6 0 .00 - < 0.01 1.00E00 1.00E00 Lewis x epitope biosynthetic process (GO:0106402) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein palmitoylation (GO:0018345) 25 0 .01 - < 0.01 1.00E00 1.00E00 protein geranylgeranylation (GO:0018344) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein farnesylation (GO:0018343) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein prenylation (GO:0018342) 10 0 .00 - < 0.01 1.00E00 1.00E00 mRNA splice site recognition (GO:0006376) 31 0 .01 - < 0.01 1.00E00 1.00E00 7-methylguanosine mRNA capping (GO:0006370) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to fatty acid (GO:0071398) 38 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to cholesterol (GO:0071397) 18 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to lipid (GO:0071396) 530 0 .15 - < 0.01 1.00E00 1.00E00 cellular response to jasmonic acid stimulus (GO:0071395) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to testosterone stimulus (GO:0071394) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to progesterone stimulus (GO:0071393) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to estradiol stimulus (GO:0071392) 38 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to estrogen stimulus (GO:0071391) 17 0 .00 - < 0.01 1.00E00 1.00E00 termination of RNA polymerase II transcription (GO:0006369) 13 0 .00 - < 0.01 1.00E00 1.00E00 transcription elongation by RNA polymerase II (GO:0006368) 42 0 .01 - < 0.01 1.00E00 1.00E00 transcription initiation at RNA polymerase II promoter (GO:0006367) 141 0 .04 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase II (GO:0006366) 421 0 .12 - < 0.01 1.00E00 1.00E00 rRNA processing (GO:0006364) 215 0 .06 - < 0.01 1.00E00 1.00E00 termination of RNA polymerase I transcription (GO:0006363) 3 0 .00 - < 0.01 1.00E00 1.00E00 transcription elongation by RNA polymerase I (GO:0006362) 7 0 .00 - < 0.01 1.00E00 1.00E00 transcription initiation at RNA polymerase I promoter (GO:0006361) 16 0 .00 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase I (GO:0006360) 41 0 .01 - < 0.01 1.00E00 1.00E00 chemokine receptor transport out of membrane raft (GO:0032600) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to mineralocorticoid stimulus (GO:0071389) 12 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cortisol stimulus (GO:0071387) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to corticosterone stimulus (GO:0071386) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glucocorticoid stimulus (GO:0071385) 58 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of organelle assembly (GO:1902117) 91 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to corticosteroid stimulus (GO:0071384) 67 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of organelle assembly (GO:1902116) 49 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to steroid hormone stimulus (GO:0071383) 159 0 .05 - < 0.01 1.00E00 1.00E00 regulation of organelle assembly (GO:1902115) 237 0 .07 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin E stimulus (GO:0071380) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription by RNA polymerase III (GO:0006359) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902110) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription by RNA polymerase II (GO:0006357) 2704 0 .79 - < 0.01 1.00E00 1.00E00 regulation of transcription by RNA polymerase I (GO:0006356) 48 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA-templated transcription (GO:0006355) 3480 0 1.01 - < 0.01 5.98E-01 1.00E00 DNA-templated transcription elongation (GO:0006354) 50 0 .01 - < 0.01 1.00E00 1.00E00 DNA-templated transcription termination (GO:0006353) 24 0 .01 - < 0.01 1.00E00 1.00E00 DNA-templated transcription initiation (GO:0006352) 175 0 .05 - < 0.01 1.00E00 1.00E00 DNA-templated transcription (GO:0006351) 554 0 .16 - < 0.01 1.00E00 1.00E00 intracellular transport of virus (GO:0075733) 8 0 .00 - < 0.01 1.00E00 1.00E00 viral penetration into host nucleus (GO:0075732) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to prostaglandin stimulus (GO:0071379) 22 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to growth hormone stimulus (GO:0071378) 23 0 .01 - < 0.01 1.00E00 1.00E00 protein C-linked glycosylation via tryptophan (GO:0018317) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glucagon stimulus (GO:0071377) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902109) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to corticotropin-releasing hormone stimulus (GO:0071376) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial membrane permeability involved in apoptotic process (GO:1902108) 21 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to peptide hormone stimulus (GO:0071375) 296 0 .09 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte differentiation (GO:1902107) 193 0 .06 - < 0.01 1.00E00 1.00E00 cellular response to parathyroid hormone stimulus (GO:0071374) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte differentiation (GO:1902106) 116 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to luteinizing hormone stimulus (GO:0071373) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte differentiation (GO:1902105) 334 0 .10 - < 0.01 1.00E00 1.00E00 cellular response to follicle-stimulating hormone stimulus (GO:0071372) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metaphase/anaphase transition of meiotic cell cycle (GO:1902104) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to gonadotropin stimulus (GO:0071371) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of metaphase/anaphase transition of meiotic cell cycle (GO:1902103) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metaphase/anaphase transition of meiotic cell cycle (GO:1902102) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of hair follicle development (GO:0051799) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of hair follicle development (GO:0051798) 12 0 .00 - < 0.01 1.00E00 1.00E00 DNA methylation-dependent constitutive heterochromatin formation (GO:0006346) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of hair follicle development (GO:0051797) 20 0 .01 - < 0.01 1.00E00 1.00E00 protein depalmitoleylation (GO:1990697) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of timing of catagen (GO:0051796) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of timing of catagen (GO:0051795) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of timing of catagen (GO:0051794) 4 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid catabolic process (GO:0051793) 5 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid biosynthetic process (GO:0051792) 6 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty acid metabolic process (GO:0051791) 15 0 .00 - < 0.01 1.00E00 1.00E00 short-chain fatty acid biosynthetic process (GO:0051790) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to epidermal growth factor stimulus (GO:0071364) 44 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to growth factor stimulus (GO:0071363) 513 0 .15 - < 0.01 1.00E00 1.00E00 cellular response to ether (GO:0071362) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to ethanol (GO:0071361) 15 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to exogenous dsRNA (GO:0071360) 17 0 .00 - < 0.01 1.00E00 1.00E00 chromatin remodeling (GO:0006338) 1010 0 .29 - < 0.01 1.00E00 1.00E00 nucleosome disassembly (GO:0006337) 21 0 .01 - < 0.01 1.00E00 1.00E00 response to misfolded protein (GO:0051788) 21 0 .01 - < 0.01 1.00E00 1.00E00 DNA replication-dependent chromatin assembly (GO:0006335) 6 0 .00 - < 0.01 1.00E00 1.00E00 nucleosome assembly (GO:0006334) 90 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear division (GO:0051785) 62 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear division (GO:0051784) 47 0 .01 - < 0.01 1.00E00 1.00E00 regulation of nuclear division (GO:0051783) 147 0 .04 - < 0.01 1.00E00 1.00E00 DNA double-strand break attachment to nuclear envelope (GO:1990683) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell division (GO:0051782) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell division (GO:0051781) 98 0 .03 - < 0.01 1.00E00 1.00E00 behavioral response to nutrient (GO:0051780) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to melanocyte-stimulating hormone (GO:1990680) 3 0 .00 - < 0.01 1.00E00 1.00E00 establishment of integrated proviral latency (GO:0075713) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to dsRNA (GO:0071359) 23 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to type III interferon (GO:0071358) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to type I interferon (GO:0071357) 49 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to tumor necrosis factor (GO:0071356) 148 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-9 (GO:0071355) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-6 (GO:0071354) 28 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-4 (GO:0071353) 32 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-2 (GO:0071352) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-18 (GO:0071351) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-15 (GO:0071350) 10 0 .00 - < 0.01 1.00E00 1.00E00 chromatin organization (GO:0006325) 1149 0 .33 - < 0.01 1.00E00 1.00E00 response to redox state (GO:0051775) 14 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-12 (GO:0071349) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-11 (GO:0071348) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-1 (GO:0071347) 75 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to type II interferon (GO:0071346) 84 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to cytokine stimulus (GO:0071345) 770 0 .22 - < 0.01 1.00E00 1.00E00 diphosphate metabolic process (GO:0071344) 4 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle acetylcholine-gated channel clustering (GO:0071340) 8 0 .00 - < 0.01 1.00E00 1.00E00 DNA transposition (GO:0006313) 2 0 .00 - < 0.01 1.00E00 1.00E00 actin crosslink formation (GO:0051764) 14 0 .00 - < 0.01 1.00E00 1.00E00 mitotic recombination (GO:0006312) 20 0 .01 - < 0.01 1.00E00 1.00E00 meiotic gene conversion (GO:0006311) 3 0 .00 - < 0.01 1.00E00 1.00E00 DNA recombination (GO:0006310) 252 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of hair follicle cell proliferation (GO:0071338) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hair follicle cell proliferation (GO:0071336) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091) 14 0 .00 - < 0.01 1.00E00 1.00E00 hair follicle cell proliferation (GO:0071335) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glucose stimulus (GO:0071333) 81 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to fructose stimulus (GO:0071332) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hexose stimulus (GO:0071331) 84 0 .02 - < 0.01 1.00E00 1.00E00 apoptotic DNA fragmentation (GO:0006309) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nitrogen compound (GO:1901699) 626 0 .18 - < 0.01 1.00E00 1.00E00 DNA catabolic process (GO:0006308) 22 0 .01 - < 0.01 1.00E00 1.00E00 response to nitrogen compound (GO:1901698) 1056 0 .31 - < 0.01 1.00E00 1.00E00 DNA alkylation repair (GO:0006307) 11 0 .00 - < 0.01 1.00E00 1.00E00 homologous chromosome movement towards spindle pole in meiosis I anaphase (GO:0051758) 1 0 .00 - < 0.01 1.00E00 1.00E00 cannabinoid biosynthetic process (GO:1901696) 3 0 .00 - < 0.01 1.00E00 1.00E00 DNA modification (GO:0006304) 30 0 .01 - < 0.01 1.00E00 1.00E00 double-strand break repair via nonhomologous end joining (GO:0006303) 49 0 .01 - < 0.01 1.00E00 1.00E00 meiotic sister chromatid cohesion, centromeric (GO:0051754) 5 0 .00 - < 0.01 1.00E00 1.00E00 sebum secreting cell proliferation (GO:1990654) 1 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair (GO:0006302) 219 0 .06 - < 0.01 1.00E00 1.00E00 postreplication repair (GO:0006301) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of innate immune response (GO:0045089) 304 0 .09 - < 0.01 1.00E00 1.00E00 regulation of innate immune response (GO:0045088) 474 0 .14 - < 0.01 1.00E00 1.00E00 innate immune response (GO:0045087) 783 0 .23 - < 0.01 1.00E00 1.00E00 cellular response to sucrose stimulus (GO:0071329) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to monosaccharide stimulus (GO:0071326) 86 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to disaccharide stimulus (GO:0071324) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to carbohydrate stimulus (GO:0071322) 96 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to cGMP (GO:0071321) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cAMP (GO:0071320) 55 0 .02 - < 0.01 1.00E00 1.00E00 glutathione derivative biosynthetic process (GO:1901687) 4 0 .00 - < 0.01 1.00E00 1.00E00 glutathione derivative metabolic process (GO:1901685) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to prolactin (GO:1990646) 2 0 .00 - < 0.01 1.00E00 1.00E00 arsenate ion transmembrane transport (GO:1901684) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to iron ion starvation (GO:1990641) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to ATP (GO:0071318) 19 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to isoquinoline alkaloid (GO:0071317) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nicotine (GO:0071316) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of viral genome replication (GO:0045071) 50 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to morphine (GO:0071315) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of viral genome replication (GO:0045070) 31 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to cocaine (GO:0071314) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to caffeine (GO:0071313) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to alkaloid (GO:0071312) 39 0 .01 - < 0.01 1.00E00 1.00E00 nucleotide transmembrane transport (GO:1901679) 27 0 .01 - < 0.01 1.00E00 1.00E00 iron coordination entity transport (GO:1901678) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to prolactin (GO:1990637) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic spindle assembly (GO:1901673) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of superoxide dismutase activity (GO:1901671) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of viral genome replication (GO:0045069) 80 0 .02 - < 0.01 1.00E00 1.00E00 regulatory T cell differentiation (GO:0045066) 8 0 .00 - < 0.01 1.00E00 1.00E00 cytotoxic T cell differentiation (GO:0045065) 1 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 2 cell differentiation (GO:0045064) 9 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 1 cell differentiation (GO:0045063) 15 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to vitamin K (GO:0071307) 2 0 .00 - < 0.01 1.00E00 1.00E00 extrathymic T cell selection (GO:0045062) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to vitamin E (GO:0071306) 1 0 .00 - < 0.01 1.00E00 1.00E00 thymic T cell selection (GO:0045061) 21 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to vitamin D (GO:0071305) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative thymic T cell selection (GO:0045060) 12 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to vitamin B1 (GO:0071301) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to retinoic acid (GO:0071300) 67 0 .02 - < 0.01 1.00E00 1.00E00 germline cell cycle switching, mitotic to meiotic cell cycle (GO:0051729) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of superoxide dismutase activity (GO:1901668) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle switching, mitotic to meiotic cell cycle (GO:0051728) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immature T cell proliferation in thymus (GO:0033092) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial inner membrane fusion (GO:1990627) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immature T cell proliferation (GO:0033091) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell cycle (GO:0051726) 1070 0 .31 - < 0.01 1.00E00 1.00E00 protein de-ADP-ribosylation (GO:0051725) 6 0 .00 - < 0.01 1.00E00 1.00E00 quinone biosynthetic process (GO:1901663) 15 0 .00 - < 0.01 1.00E00 1.00E00 quinone catabolic process (GO:1901662) 1 0 .00 - < 0.01 1.00E00 1.00E00 quinone metabolic process (GO:1901661) 20 0 .01 - < 0.01 1.00E00 1.00E00 calcium ion export (GO:1901660) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive thymic T cell selection (GO:0045059) 12 0 .00 - < 0.01 1.00E00 1.00E00 T cell selection (GO:0045058) 48 0 .01 - < 0.01 1.00E00 1.00E00 transcytosis (GO:0045056) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulated exocytosis (GO:0045055) 139 0 .04 - < 0.01 1.00E00 1.00E00 constitutive secretory pathway (GO:0045054) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein retention in Golgi apparatus (GO:0045053) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into ER membrane by stop-transfer membrane-anchor sequence (GO:0045050) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell differentiation in thymus (GO:0033089) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of immature T cell proliferation in thymus (GO:0033088) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of immature T cell proliferation (GO:0033087) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell differentiation in thymus (GO:0033085) 11 0 .00 - < 0.01 1.00E00 1.00E00 glycosyl compound biosynthetic process (GO:1901659) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of immature T cell proliferation in thymus (GO:0033084) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycosyl compound catabolic process (GO:1901658) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of immature T cell proliferation (GO:0033083) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycosyl compound metabolic process (GO:1901657) 85 0 .02 - < 0.01 1.00E00 1.00E00 regulation of extrathymic T cell differentiation (GO:0033082) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycoside transport (GO:1901656) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell differentiation in thymus (GO:0033081) 28 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to stimulus (GO:0051716) 6422 1 1.87 - .53 6.73E-01 1.00E00 cellular response to ketone (GO:1901655) 107 0 .03 - < 0.01 1.00E00 1.00E00 immature T cell proliferation in thymus (GO:0033080) 5 0 .00 - < 0.01 1.00E00 1.00E00 cytolysis in another organism (GO:0051715) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to ketone (GO:1901654) 223 0 .07 - < 0.01 1.00E00 1.00E00 cellular response to peptide (GO:1901653) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to peptide (GO:1901652) 884 0 .26 - < 0.01 1.00E00 1.00E00 positive regulation of killing of cells of another organism (GO:0051712) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translational initiation in response to stress (GO:1990611) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into ER membrane (GO:0045048) 31 0 .01 - < 0.01 1.00E00 1.00E00 protein targeting to ER (GO:0045047) 36 0 .01 - < 0.01 1.00E00 1.00E00 protein import into peroxisome membrane (GO:0045046) 6 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell migration (GO:0090497) 58 0 .02 - < 0.01 1.00E00 1.00E00 dopamine uptake (GO:0090494) 12 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine uptake (GO:0090493) 12 0 .00 - < 0.01 1.00E00 1.00E00 protein import into mitochondrial intermembrane space (GO:0045041) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial outer membrane (GO:0045040) 14 0 .00 - < 0.01 1.00E00 1.00E00 immature T cell proliferation (GO:0033079) 5 0 .00 - < 0.01 1.00E00 1.00E00 extrathymic T cell differentiation (GO:0033078) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell differentiation in thymus (GO:0033077) 65 0 .02 - < 0.01 1.00E00 1.00E00 isoquinoline alkaloid metabolic process (GO:0033076) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of killing of cells of another organism (GO:0051709) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synoviocyte proliferation (GO:1901647) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to other organism (GO:0051707) 1429 0 .42 - < 0.01 1.00E00 1.00E00 regulation of synoviocyte proliferation (GO:1901645) 3 0 .00 - < 0.01 1.00E00 1.00E00 biological process involved in intraspecies interaction between organisms (GO:0051703) 59 0 .02 - < 0.01 1.00E00 1.00E00 nucleoside transmembrane transport (GO:1901642) 8 0 .00 - < 0.01 1.00E00 1.00E00 dark adaptation (GO:1990603) 2 0 .00 - < 0.01 1.00E00 1.00E00 biological process involved in interaction with symbiont (GO:0051702) 35 0 .01 - < 0.01 1.00E00 1.00E00 biological process involved in interaction with host (GO:0051701) 149 0 .04 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial inner membrane (GO:0045039) 13 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to chloroplast (GO:0045036) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide-sugar transmembrane transport (GO:0090481) 12 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleotide-sugar transmembrane transport (GO:0090480) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle membrane organization (GO:1901634) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle membrane organization (GO:1901632) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of presynaptic membrane organization (GO:1901631) 2 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane fusion (GO:0045026) 32 0 .01 - < 0.01 1.00E00 1.00E00 G0 to G1 transition (GO:0045023) 3 0 .00 - < 0.01 1.00E00 1.00E00 early endosome to late endosome transport (GO:0045022) 25 0 .01 - < 0.01 1.00E00 1.00E00 dibasic protein processing (GO:0090472) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular pigmentation (GO:0033059) 61 0 .02 - < 0.01 1.00E00 1.00E00 directional locomotion (GO:0033058) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA wobble uridine modification (GO:0070899) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase III preinitiation complex assembly (GO:0070898) 1 0 .00 - < 0.01 1.00E00 1.00E00 transcription preinitiation complex assembly (GO:0070897) 77 0 .02 - < 0.01 1.00E00 1.00E00 regulation of presynaptic membrane organization (GO:1901629) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of postsynaptic membrane organization (GO:1901628) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of postsynaptic membrane organization (GO:1901627) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic membrane organization (GO:1901626) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to ergosterol (GO:1901625) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte chemotaxis (GO:1901624) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte chemotaxis (GO:1901623) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:1901621) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:1901620) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nitric oxide biosynthetic process (GO:0045019) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycerolipid biosynthetic process (GO:0045017) 210 0 .06 - < 0.01 1.00E00 1.00E00 mitochondrial magnesium ion transmembrane transport (GO:0045016) 2 0 .00 - < 0.01 1.00E00 1.00E00 actin nucleation (GO:0045010) 28 0 .01 - < 0.01 1.00E00 1.00E00 intracellular glutamate homeostasis (GO:0090461) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic sister chromatid segregation (GO:0033048) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mitotic sister chromatid segregation (GO:0033047) 58 0 .02 - < 0.01 1.00E00 1.00E00 platelet alpha granule organization (GO:0070889) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sister chromatid segregation (GO:0033046) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of sister chromatid segregation (GO:0033045) 108 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to chemical stimulus (GO:0070887) 1968 1 .57 + 1.74 4.53E-01 1.00E00 regulation of chromosome organization (GO:0033044) 242 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of calcineurin-NFAT signaling cascade (GO:0070886) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of organelle organization (GO:0033043) 1174 0 .34 - < 0.01 1.00E00 1.00E00 negative regulation of calcineurin-NFAT signaling cascade (GO:0070885) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcineurin-NFAT signaling cascade (GO:0070884) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of proline transport (GO:0070881) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vesicle transport along microtubule (GO:1901610) 5 0 .00 - < 0.01 1.00E00 1.00E00 depyrimidination (GO:0045008) 8 0 .00 - < 0.01 1.00E00 1.00E00 intracellular aspartate homeostasis (GO:0090459) 1 0 .00 - < 0.01 1.00E00 1.00E00 depurination (GO:0045007) 4 0 .00 - < 0.01 1.00E00 1.00E00 DNA deamination (GO:0045006) 13 0 .00 - < 0.01 1.00E00 1.00E00 DNA-templated DNA replication maintenance of fidelity (GO:0045005) 57 0 .02 - < 0.01 1.00E00 1.00E00 DNA replication proofreading (GO:0045004) 3 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair via synthesis-dependent strand annealing (GO:0045003) 8 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair via single-strand annealing (GO:0045002) 6 0 .00 - < 0.01 1.00E00 1.00E00 polysaccharide localization (GO:0033037) 2 0 .00 - < 0.01 1.00E00 1.00E00 macromolecule localization (GO:0033036) 2388 0 .70 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid cell apoptotic process (GO:0033034) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vesicle transport along microtubule (GO:1901608) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid cell apoptotic process (GO:0033033) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen metabolic process (GO:0070875) 20 0 .01 - < 0.01 1.00E00 1.00E00 alpha-amino acid biosynthetic process (GO:1901607) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of myeloid cell apoptotic process (GO:0033032) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen metabolic process (GO:0070874) 10 0 .00 - < 0.01 1.00E00 1.00E00 alpha-amino acid catabolic process (GO:1901606) 95 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil apoptotic process (GO:0033031) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glycogen metabolic process (GO:0070873) 37 0 .01 - < 0.01 1.00E00 1.00E00 alpha-amino acid metabolic process (GO:1901605) 193 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil apoptotic process (GO:0033030) 2 0 .00 - < 0.01 1.00E00 1.00E00 endocytic iron import into cell (GO:0140298) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-glutamate ADP-deribosylation (GO:0140291) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine ADP-deribosylation (GO:0140290) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil apoptotic process (GO:0033029) 8 0 .00 - < 0.01 1.00E00 1.00E00 myeloid cell apoptotic process (GO:0033028) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell apoptotic process (GO:0033027) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell apoptotic process (GO:0033026) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell apoptotic process (GO:0033025) 3 0 .00 - < 0.01 1.00E00 1.00E00 mast cell apoptotic process (GO:0033024) 2 0 .00 - < 0.01 1.00E00 1.00E00 mast cell homeostasis (GO:0033023) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein exit from endoplasmic reticulum (GO:0070863) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein exit from endoplasmic reticulum (GO:0070862) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein exit from endoplasmic reticulum (GO:0070861) 23 0 .01 - < 0.01 1.00E00 1.00E00 endosome fission (GO:0140285) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to nuclear envelope (GO:0090435) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of bile acid biosynthetic process (GO:0070859) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid biosynthetic process (GO:0070858) 3 0 .00 - < 0.01 1.00E00 1.00E00 tetrapyrrole catabolic process (GO:0033015) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bile acid biosynthetic process (GO:0070857) 11 0 .00 - < 0.01 1.00E00 1.00E00 tetrapyrrole biosynthetic process (GO:0033014) 29 0 .01 - < 0.01 1.00E00 1.00E00 tetrapyrrole metabolic process (GO:0033013) 57 0 .02 - < 0.01 1.00E00 1.00E00 repair of kinetochore microtubule attachment defect (GO:0140274) 2 0 .00 - < 0.01 1.00E00 1.00E00 activation of meiosis (GO:0090427) 6 0 .00 - < 0.01 1.00E00 1.00E00 repair of mitotic kinetochore microtubule attachment defect (GO:0140273) 2 0 .00 - < 0.01 1.00E00 1.00E00 acinar cell differentiation (GO:0090425) 5 0 .00 - < 0.01 1.00E00 1.00E00 hexose import across plasma membrane (GO:0140271) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell activation involved in immune response (GO:0033008) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell activation involved in immune response (GO:0033007) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to epidermal growth factor (GO:0070849) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mast cell activation involved in immune response (GO:0033006) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to growth factor (GO:0070848) 543 0 .16 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell activation (GO:0033005) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell activation (GO:0033004) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell activation (GO:0033003) 19 0 .01 - < 0.01 1.00E00 1.00E00 polyubiquitinated misfolded protein transport (GO:0070845) 1 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell proliferation (GO:0033002) 44 0 .01 - < 0.01 1.00E00 1.00E00 polyubiquitinated protein transport (GO:0070844) 1 0 .00 - < 0.01 1.00E00 1.00E00 misfolded protein transport (GO:0070843) 1 0 .00 - < 0.01 1.00E00 1.00E00 aggresome assembly (GO:0070842) 6 0 .00 - < 0.01 1.00E00 1.00E00 inclusion body assembly (GO:0070841) 10 0 .00 - < 0.01 1.00E00 1.00E00 doxorubicin metabolic process (GO:0044598) 10 0 .00 - < 0.01 1.00E00 1.00E00 daunorubicin metabolic process (GO:0044597) 9 0 .00 - < 0.01 1.00E00 1.00E00 malonate catabolic process (GO:0090410) 1 0 .00 - < 0.01 1.00E00 1.00E00 dehydroascorbic acid transport (GO:0070837) 13 0 .00 - < 0.01 1.00E00 1.00E00 caveola assembly (GO:0070836) 7 0 .00 - < 0.01 1.00E00 1.00E00 basement membrane assembly (GO:0070831) 4 0 .00 - < 0.01 1.00E00 1.00E00 bicellular tight junction assembly (GO:0070830) 50 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Rho-dependent protein serine/threonine kinase activity (GO:2000299) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Rho-dependent protein serine/threonine kinase activity (GO:2000298) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synapse maturation (GO:2000297) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide catabolic process (GO:2000296) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide catabolic process (GO:2000295) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of defecation (GO:2000293) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of defecation (GO:2000292) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myoblast proliferation (GO:2000291) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myotome development (GO:2000290) 1 0 .00 - < 0.01 1.00E00 1.00E00 organophosphate biosynthetic process (GO:0090407) 565 0 .16 - < 0.01 1.00E00 1.00E00 cell-cell fusion (GO:0140253) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation protein catabolic process at postsynapse (GO:0140252) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation protein catabolic process at presynapse (GO:0140251) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation protein catabolic process at synapse (GO:0140250) 8 0 .00 - < 0.01 1.00E00 1.00E00 oxidative stress-induced premature senescence (GO:0090403) 4 0 .00 - < 0.01 1.00E00 1.00E00 oncogene-induced cell senescence (GO:0090402) 6 0 .00 - < 0.01 1.00E00 1.00E00 stress-induced premature senescence (GO:0090400) 8 0 .00 - < 0.01 1.00E00 1.00E00 heterochromatin organization (GO:0070828) 13 0 .00 - < 0.01 1.00E00 1.00E00 butyryl-CoA catabolic process (GO:0044580) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myoblast proliferation (GO:2000288) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myotome development (GO:2000287) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein catabolic process at postsynapse (GO:0140249) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amino acid biosynthetic process (GO:2000284) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amino acid biosynthetic process (GO:2000283) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein catabolic process at synapse (GO:0140246) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amino acid biosynthetic process (GO:2000282) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation at postsynapse (GO:0140245) 6 0 .00 - < 0.01 1.00E00 1.00E00 peripheral nervous system neuron axonogenesis (GO:0048936) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation at presynapse (GO:0140244) 3 0 .00 - < 0.01 1.00E00 1.00E00 peripheral nervous system neuron development (GO:0048935) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation at synapse (GO:0140243) 9 0 .00 - < 0.01 1.00E00 1.00E00 peripheral nervous system neuron differentiation (GO:0048934) 16 0 .00 - < 0.01 1.00E00 1.00E00 translation at postsynapse (GO:0140242) 1 0 .00 - < 0.01 1.00E00 1.00E00 translation at synapse (GO:0140241) 2 0 .00 - < 0.01 1.00E00 1.00E00 [4Fe-4S] cluster assembly (GO:0044572) 5 0 .00 - < 0.01 1.00E00 1.00E00 [2Fe-2S] cluster assembly (GO:0044571) 10 0 .00 - < 0.01 1.00E00 1.00E00 hydrogen sulfide biosynthetic process (GO:0070814) 3 0 .00 - < 0.01 1.00E00 1.00E00 hydrogen sulfide metabolic process (GO:0070813) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA biosynthetic process (GO:2000279) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA biosynthetic process (GO:2000278) 92 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative phosphorylation uncoupler activity (GO:2000276) 1 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic endocytosis (GO:0140239) 8 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic endocytosis (GO:0140238) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of signaling receptor activity (GO:2000273) 20 0 .01 - < 0.01 1.00E00 1.00E00 dAMP salvage (GO:0106383) 3 0 .00 - < 0.01 1.00E00 1.00E00 translation at presynapse (GO:0140236) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of signaling receptor activity (GO:2000272) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast apoptotic process (GO:2000271) 10 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleotide salvage (GO:0106381) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast apoptotic process (GO:2000270) 7 0 .00 - < 0.01 1.00E00 1.00E00 lateral line system development (GO:0048925) 3 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleotide salvage (GO:0106380) 8 0 .00 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast hair cell differentiation (GO:0048923) 1 0 .00 - < 0.01 1.00E00 1.00E00 anterograde axonal transport of neurotransmitter receptor complex (GO:0140231) 1 0 .00 - < 0.01 1.00E00 1.00E00 dendritic cell proliferation (GO:0044565) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein transport out of membrane raft (GO:0032599) 1 0 .00 - < 0.01 1.00E00 1.00E00 B cell receptor transport into membrane raft (GO:0032597) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein transport into membrane raft (GO:0032596) 5 0 .00 - < 0.01 1.00E00 1.00E00 B cell receptor transport within lipid bilayer (GO:0032595) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein transport within lipid bilayer (GO:0032594) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast apoptotic process (GO:2000269) 19 0 .01 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast development (GO:0048919) 1 0 .00 - < 0.01 1.00E00 1.00E00 serotonin-gated cation-selective signaling pathway (GO:0140227) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood coagulation, common pathway (GO:2000261) 1 0 .00 - < 0.01 1.00E00 1.00E00 posterior lateral line development (GO:0048916) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood coagulation, common pathway (GO:2000260) 1 0 .00 - < 0.01 1.00E00 1.00E00 posterior lateral line system development (GO:0048915) 1 0 .00 - < 0.01 1.00E00 1.00E00 relaxation of smooth muscle (GO:0044557) 6 0 .00 - < 0.01 1.00E00 1.00E00 secondary metabolite biosynthetic process (GO:0044550) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein activation cascade (GO:2000258) 1 0 .00 - < 0.01 1.00E00 1.00E00 ER-dependent peroxisome organization (GO:0032581) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein activation cascade (GO:2000257) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of male germ cell proliferation (GO:2000256) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of male germ cell proliferation (GO:2000255) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of male germ cell proliferation (GO:2000254) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of feeding behavior (GO:2000253) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of feeding behavior (GO:2000252) 6 0 .00 - < 0.01 1.00E00 1.00E00 guanine nucleotide transport (GO:0001408) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of long-chain fatty acid import into cell (GO:0140214) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of long-chain fatty acid import into cell (GO:0140213) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of long-chain fatty acid import into cell (GO:0140212) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metaphase/anaphase transition of cell cycle (GO:1902099) 96 0 .03 - < 0.01 1.00E00 1.00E00 NLRP3 inflammasome complex assembly (GO:0044546) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of flagellated sperm motility (GO:1902093) 15 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin K (GO:0032571) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to progesterone (GO:0032570) 43 0 .01 - < 0.01 1.00E00 1.00E00 apoptotic process in response to mitochondrial fragmentation (GO:0140208) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA surveillance (GO:0106354) 8 0 .00 - < 0.01 1.00E00 1.00E00 tripeptide import across plasma membrane (GO:0140207) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of reproductive process (GO:2000243) 90 0 .03 - < 0.01 1.00E00 1.00E00 dipeptide import across plasma membrane (GO:0140206) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of reproductive process (GO:2000242) 73 0 .02 - < 0.01 1.00E00 1.00E00 oligopeptide import across plasma membrane (GO:0140205) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of reproductive process (GO:2000241) 204 0 .06 - < 0.01 1.00E00 1.00E00 long-chain fatty acid import into cell (GO:0044539) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein-FAD linkage (GO:0018293) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of circulating fibrinogen levels (GO:0044537) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor localization to postsynaptic specialization membrane (GO:0099645) 17 0 .00 - < 0.01 1.00E00 1.00E00 signal release from synapse (GO:0099643) 86 0 .03 - < 0.01 1.00E00 1.00E00 retrograde axonal protein transport (GO:0099642) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion import into sarcoplasmic reticulum (GO:1902082) 2 0 .00 - < 0.01 1.00E00 1.00E00 anterograde axonal protein transport (GO:0099641) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion import into sarcoplasmic reticulum (GO:1902081) 2 0 .00 - < 0.01 1.00E00 1.00E00 axo-dendritic protein transport (GO:0099640) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion import into sarcoplasmic reticulum (GO:1902080) 4 0 .00 - < 0.01 1.00E00 1.00E00 snRNA methylation (GO:0106349) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tRNA processing (GO:2000235) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of rRNA processing (GO:2000234) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of rRNA processing (GO:2000233) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of rRNA processing (GO:2000232) 15 0 .00 - < 0.01 1.00E00 1.00E00 omega-hydroxyceramide biosynthetic process (GO:0106342) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic stellate cell proliferation (GO:2000231) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport, endosome to plasma membrane (GO:0099639) 9 0 .00 - < 0.01 1.00E00 1.00E00 endosome to plasma membrane protein transport (GO:0099638) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lateral motor column neuron migration (GO:1902078) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport (GO:0099637) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial mRNA stability (GO:0044528) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lateral motor column neuron migration (GO:1902076) 1 0 .00 - < 0.01 1.00E00 1.00E00 iron incorporation into metallo-sulfur cluster (GO:0018283) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to salt (GO:1902075) 6 0 .00 - < 0.01 1.00E00 1.00E00 metal incorporation into metallo-sulfur cluster (GO:0018282) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to salt (GO:1902074) 23 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to postsynaptic specialization membrane (GO:0099633) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902073) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein sulfhydration (GO:0044524) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hypoxia-inducible factor-1alpha signaling pathway (GO:1902071) 1 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic neurotransmitter receptor cycle (GO:0099630) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sphingolipid mediated signaling pathway (GO:1902070) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pancreatic stellate cell proliferation (GO:2000229) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of pancreatic A cell differentiation (GO:2000227) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pancreatic A cell differentiation (GO:2000226) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of testosterone biosynthetic process (GO:2000225) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of testosterone biosynthetic process (GO:2000224) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein N-linked glycosylation via asparagine (GO:0018279) 43 0 .01 - < 0.01 1.00E00 1.00E00 protein deamination (GO:0018277) 2 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor diffusion trapping (GO:0099628) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sphingolipid mediated signaling pathway (GO:1902068) 2 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor cycle (GO:0099627) 1 0 .00 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle cell membrane repolarization (GO:0099625) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to L-glutamate (GO:1902065) 18 0 .01 - < 0.01 1.00E00 1.00E00 protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine (GO:0018272) 1 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell membrane repolarization (GO:0099624) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell membrane repolarization (GO:0099623) 27 0 .01 - < 0.01 1.00E00 1.00E00 cardiac muscle cell membrane repolarization (GO:0099622) 21 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial translation (GO:0032543) 109 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate metabolic process (GO:2000213) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glutamate metabolic process (GO:2000212) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamate metabolic process (GO:2000211) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anoikis (GO:2000210) 7 0 .00 - < 0.01 1.00E00 1.00E00 isopeptide cross-linking (GO:0018262) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to axon (GO:0099612) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of action potential firing threshold (GO:0099611) 2 0 .00 - < 0.01 1.00E00 1.00E00 mismatch repair (GO:0006298) 31 0 .01 - < 0.01 1.00E00 1.00E00 symbiont-mediated disruption of host anatomical structure (GO:0052111) 4 0 .00 - < 0.01 1.00E00 1.00E00 action potential initiation (GO:0099610) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA gap filling (GO:0006297) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, preincision complex assembly (GO:0006294) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell projection size (GO:0032536) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular component size (GO:0032535) 355 0 .10 - < 0.01 1.00E00 1.00E00 pyrimidine dimer repair (GO:0006290) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microvillus assembly (GO:0032534) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anoikis (GO:2000209) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of microvillus length (GO:0032532) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ribosomal small subunit export from nucleus (GO:2000208) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microvillus organization (GO:0032530) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ribosomal small subunit export from nucleus (GO:2000206) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ribosomal large subunit export from nucleus (GO:2000204) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ribosomal large subunit export from nucleus (GO:2000203) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ribosomal subunit export from nucleus (GO:2000202) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ribosomal subunit export from nucleus (GO:2000201) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ribosomal subunit export from nucleus (GO:2000200) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of action potential firing pattern (GO:0099608) 1 0 .00 - < 0.01 1.00E00 1.00E00 lateral attachment of mitotic spindle microtubules to kinetochore (GO:0099607) 1 0 .00 - < 0.01 1.00E00 1.00E00 polyamine transmembrane transport (GO:1902047) 9 0 .00 - < 0.01 1.00E00 1.00E00 microtubule plus-end directed mitotic chromosome migration (GO:0099606) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of action potential firing rate (GO:0099605) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Fas signaling pathway (GO:1902045) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Fas signaling pathway (GO:1902044) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902042) 30 0 .01 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair (GO:0006289) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter receptor activity (GO:0099601) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902041) 47 0 .01 - < 0.01 1.00E00 1.00E00 base-excision repair, gap-filling (GO:0006287) 14 0 .00 - < 0.01 1.00E00 1.00E00 base-excision repair, AP site formation (GO:0006285) 12 0 .00 - < 0.01 1.00E00 1.00E00 base-excision repair (GO:0006284) 45 0 .01 - < 0.01 1.00E00 1.00E00 microvillus organization (GO:0032528) 13 0 .00 - < 0.01 1.00E00 1.00E00 transcription-coupled nucleotide-excision repair (GO:0006283) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein exit from endoplasmic reticulum (GO:0032527) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA repair (GO:0006282) 230 0 .07 - < 0.01 1.00E00 1.00E00 response to retinoic acid (GO:0032526) 106 1 .03 + 32.36 3.05E-02 1.00E00 DNA repair (GO:0006281) 523 0 .15 - < 0.01 1.00E00 1.00E00 somite rostral/caudal axis specification (GO:0032525) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein-DNA covalent cross-linking repair (GO:0106300) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic stem cell differentiation (GO:1902038) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hematopoietic stem cell differentiation (GO:1902037) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic stem cell differentiation (GO:1902036) 18 0 .01 - < 0.01 1.00E00 1.00E00 protein O-linked glycosylation via threonine (GO:0018243) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic stem cell proliferation (GO:1902035) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein O-linked glycosylation via serine (GO:0018242) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hematopoietic stem cell proliferation (GO:1902034) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic stem cell proliferation (GO:1902033) 15 0 .00 - < 0.01 1.00E00 1.00E00 post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery (GO:0000973) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NADP metabolic process (GO:1902031) 8 0 .00 - < 0.01 1.00E00 1.00E00 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery (GO:0000972) 7 0 .00 - < 0.01 1.00E00 1.00E00 RNA-templated DNA biosynthetic process (GO:0006278) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA replication (GO:0006275) 120 0 .03 - < 0.01 1.00E00 1.00E00 DNA replication termination (GO:0006274) 1 0 .00 - < 0.01 1.00E00 1.00E00 lagging strand elongation (GO:0006273) 4 0 .00 - < 0.01 1.00E00 1.00E00 leading strand elongation (GO:0006272) 4 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in DNA replication (GO:0006271) 15 0 .00 - < 0.01 1.00E00 1.00E00 DNA replication initiation (GO:0006270) 28 0 .01 - < 0.01 1.00E00 1.00E00 late endosome to vacuole transport via multivesicular body sorting pathway (GO:0032511) 28 0 .01 - < 0.01 1.00E00 1.00E00 endosome to lysosome transport via multivesicular body sorting pathway (GO:0032510) 18 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to L-ascorbic acid (GO:0071298) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to vitamin (GO:0071295) 21 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to zinc ion (GO:0071294) 25 0 .01 - < 0.01 1.00E00 1.00E00 rRNA 5'-end processing (GO:0000967) 5 0 .00 - < 0.01 1.00E00 1.00E00 nitrate import (GO:1902025) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA 5'-end processing (GO:0000966) 38 0 .01 - < 0.01 1.00E00 1.00E00 L-histidine transport (GO:1902024) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA 3'-end processing (GO:0000965) 8 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine (GO:0018231) 15 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA 5'-end processing (GO:0000964) 4 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-L-cysteine S-palmitoylation (GO:0018230) 15 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine transport (GO:1902022) 9 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA processing (GO:0000963) 23 0 .01 - < 0.01 1.00E00 1.00E00 DNA replication, synthesis of primer (GO:0006269) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial RNA catabolic process (GO:0000962) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cilium-dependent cell motility (GO:1902020) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial RNA catabolic process (GO:0000961) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial RNA catabolic process (GO:0000960) 5 0 .00 - < 0.01 1.00E00 1.00E00 DNA topological change (GO:0006265) 10 0 .00 - < 0.01 1.00E00 1.00E00 endosome transport via multivesicular body sorting pathway (GO:0032509) 43 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial DNA replication (GO:0006264) 10 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein location in cell (GO:0032507) 59 0 .02 - < 0.01 1.00E00 1.00E00 cytokinetic process (GO:0032506) 45 0 .01 - < 0.01 1.00E00 1.00E00 DNA-templated DNA replication (GO:0006261) 142 0 .04 - < 0.01 1.00E00 1.00E00 DNA replication (GO:0006260) 201 0 .06 - < 0.01 1.00E00 1.00E00 developmental process (GO:0032502) 5794 3 1.69 + 1.78 3.60E-01 1.00E00 multicellular organismal process (GO:0032501) 6347 3 1.85 + 1.62 3.81E-01 1.00E00 cellular response to mercury ion (GO:0071288) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to manganese ion (GO:0071287) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium-dependent cell motility (GO:1902019) 33 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to magnesium ion (GO:0071286) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cilium assembly (GO:1902018) 23 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial RNA metabolic process (GO:0000959) 52 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to lithium ion (GO:0071285) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium assembly (GO:1902017) 76 0 .02 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA catabolic process (GO:0000958) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to lead ion (GO:0071284) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA catabolic process (GO:0000957) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to iron(III) ion (GO:0071283) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process (GO:0000956) 101 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to iron ion (GO:0071281) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to copper ion (GO:0071280) 26 0 .01 - < 0.01 1.00E00 1.00E00 DNA metabolic process (GO:0006259) 749 0 .22 - < 0.01 1.00E00 1.00E00 negative regulation of translation in response to endoplasmic reticulum stress (GO:1902010) 3 0 .00 - < 0.01 1.00E00 1.00E00 UDP catabolic process (GO:0006256) 3 0 .00 - < 0.01 1.00E00 1.00E00 CTP catabolic process (GO:0006254) 1 0 .00 - < 0.01 1.00E00 1.00E00 dCTP catabolic process (GO:0006253) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cobalt ion (GO:0071279) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to calcium ion (GO:0071277) 77 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-arginine methylation (GO:0018216) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cadmium ion (GO:0071276) 27 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to aluminum ion (GO:0071275) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein carboxylation (GO:0018214) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine modification (GO:0018212) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of amyloid-beta formation (GO:1902004) 21 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-tryptophan modification (GO:0018211) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amyloid-beta formation (GO:1902003) 37 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-threonine modification (GO:0018210) 47 0 .01 - < 0.01 1.00E00 1.00E00 dCMP catabolic process (GO:0006249) 6 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid transmembrane transport (GO:1902001) 14 0 .00 - < 0.01 1.00E00 1.00E00 CMP catabolic process (GO:0006248) 4 0 .00 - < 0.01 1.00E00 1.00E00 homogentisate catabolic process (GO:1902000) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein delipidation (GO:0051697) 5 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide catabolic process (GO:0006244) 21 0 .01 - < 0.01 1.00E00 1.00E00 actin filament uncapping (GO:0051695) 2 0 .00 - < 0.01 1.00E00 1.00E00 pointed-end actin filament capping (GO:0051694) 7 0 .00 - < 0.01 1.00E00 1.00E00 actin filament capping (GO:0051693) 35 0 .01 - < 0.01 1.00E00 1.00E00 CTP biosynthetic process (GO:0006241) 14 0 .00 - < 0.01 1.00E00 1.00E00 protein K69-linked ufmylation (GO:1990592) 5 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine modification (GO:0018209) 83 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-proline modification (GO:0018208) 9 0 .00 - < 0.01 1.00E00 1.00E00 L-methionine salvage (GO:0071267) 7 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-methionine modification (GO:0018206) 7 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' L-methionine biosynthetic process (GO:0071266) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine modification (GO:0018205) 117 0 .03 - < 0.01 1.00E00 1.00E00 L-methionine biosynthetic process (GO:0071265) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation in response to starvation (GO:0071264) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-histidine modification (GO:0018202) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational initiation in response to starvation (GO:0071262) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-glycine modification (GO:0018201) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-glutamic acid modification (GO:0018200) 25 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to mechanical stimulus (GO:0071260) 78 0 .02 - < 0.01 1.00E00 1.00E00 dTTP biosynthetic process (GO:0006235) 4 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of ER location (GO:0051685) 1 0 .00 - < 0.01 1.00E00 1.00E00 dTDP biosynthetic process (GO:0006233) 2 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of Golgi location (GO:0051684) 3 0 .00 - < 0.01 1.00E00 1.00E00 establishment of Golgi localization (GO:0051683) 8 0 .00 - < 0.01 1.00E00 1.00E00 dTMP biosynthetic process (GO:0006231) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to magnetism (GO:0071259) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to gravity (GO:0071258) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to electrical stimulus (GO:0071257) 12 0 .00 - < 0.01 1.00E00 1.00E00 UTP biosynthetic process (GO:0006228) 10 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine trans-autophosphorylation (GO:1990579) 1 0 .00 - < 0.01 1.00E00 1.00E00 septin ring assembly (GO:0000921) 1 0 .00 - < 0.01 1.00E00 1.00E00 dUDP biosynthetic process (GO:0006227) 2 0 .00 - < 0.01 1.00E00 1.00E00 dUMP biosynthetic process (GO:0006226) 2 0 .00 - < 0.01 1.00E00 1.00E00 UDP biosynthetic process (GO:0006225) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial L-ornithine transmembrane transport (GO:1990575) 3 0 .00 - < 0.01 1.00E00 1.00E00 localization of cell (GO:0051674) 6 0 .00 - < 0.01 1.00E00 1.00E00 UMP biosynthetic process (GO:0006222) 11 0 .00 - < 0.01 1.00E00 1.00E00 disruption of plasma membrane integrity in another organism (GO:0051673) 5 0 .00 - < 0.01 1.00E00 1.00E00 potassium ion import across plasma membrane (GO:1990573) 46 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide biosynthetic process (GO:0006221) 34 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide metabolic process (GO:0006220) 54 0 .02 - < 0.01 1.00E00 1.00E00 GDP-mannose transmembrane transport (GO:1990570) 1 0 .00 - < 0.01 1.00E00 1.00E00 transport of viral material towards nucleus (GO:0075606) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to metal ion (GO:0071248) 182 1 .05 + 18.85 5.19E-02 1.00E00 cellular response to carbon dioxide (GO:0071244) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to arsenic-containing substance (GO:0071243) 17 0 .00 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring contraction (GO:0000916) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to ammonium ion (GO:0071242) 5 0 .00 - < 0.01 1.00E00 1.00E00 actomyosin contractile ring assembly (GO:0000915) 8 0 .00 - < 0.01 1.00E00 1.00E00 glutamatergic neuron differentiation (GO:1905962) 18 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to food (GO:0071240) 1 0 .00 - < 0.01 1.00E00 1.00E00 assembly of actomyosin apparatus involved in cytokinesis (GO:0000912) 8 0 .00 - < 0.01 1.00E00 1.00E00 uridine catabolic process (GO:0006218) 2 0 .00 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine transmembrane transport (GO:1990569) 5 0 .00 - < 0.01 1.00E00 1.00E00 localization within membrane (GO:0051668) 551 0 .16 - < 0.01 1.00E00 1.00E00 cytokinesis (GO:0000910) 119 0 .03 - < 0.01 1.00E00 1.00E00 cytidine catabolic process (GO:0006216) 6 0 .00 - < 0.01 1.00E00 1.00E00 actin cortical patch localization (GO:0051666) 1 0 .00 - < 0.01 1.00E00 1.00E00 thymidine catabolic process (GO:0006214) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane raft localization (GO:0051665) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside metabolic process (GO:0006213) 18 0 .01 - < 0.01 1.00E00 1.00E00 nuclear pore localization (GO:0051664) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein polyufmylation (GO:1990564) 5 0 .00 - < 0.01 1.00E00 1.00E00 uracil catabolic process (GO:0006212) 2 0 .00 - < 0.01 1.00E00 1.00E00 thymine catabolic process (GO:0006210) 3 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of centrosome location (GO:0051661) 6 0 .00 - < 0.01 1.00E00 1.00E00 establishment of centrosome localization (GO:0051660) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to antibiotic (GO:0071236) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to alcohol (GO:1905957) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial tube morphogenesis (GO:1905956) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to L-leucine (GO:0071233) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid localization (GO:1905954) 104 1 .03 + 32.98 2.99E-02 1.00E00 negative regulation of lipid localization (GO:1905953) 46 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to folic acid (GO:0071231) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipid localization (GO:1905952) 161 1 .05 + 21.30 4.60E-02 1.00E00 cellular response to amino acid stimulus (GO:0071230) 85 0 .02 - < 0.01 1.00E00 1.00E00 cell morphogenesis (GO:0000902) 712 0 .21 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase catabolic process (GO:0006208) 3 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of mitochondrion location (GO:0051659) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial coenzyme A transmembrane transport (GO:1990559) 1 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' pyrimidine nucleobase biosynthetic process (GO:0006207) 6 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of nucleus location (GO:0051658) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase metabolic process (GO:0006206) 16 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of organelle location (GO:0051657) 11 0 .00 - < 0.01 1.00E00 1.00E00 establishment of organelle localization (GO:0051656) 421 0 .12 - < 0.01 1.00E00 1.00E00 IMP catabolic process (GO:0006204) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to capsazepine (GO:1901594) 1 0 .00 - < 0.01 1.00E00 1.00E00 dGTP catabolic process (GO:0006203) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of mitochondrion localization (GO:0051654) 32 0 .01 - < 0.01 1.00E00 1.00E00 spindle localization (GO:0051653) 66 0 .02 - < 0.01 1.00E00 1.00E00 maintenance of location in cell (GO:0051651) 81 0 .02 - < 0.01 1.00E00 1.00E00 establishment of vesicle localization (GO:0051650) 174 0 .05 - < 0.01 1.00E00 1.00E00 mitochondrial alpha-ketoglutarate transmembrane transport (GO:1990550) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to acid chemical (GO:0071229) 93 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to tumor cell (GO:0071228) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion import across plasma membrane (GO:1905949) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to molecule of fungal origin (GO:0071226) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to muramyl dipeptide (GO:0071225) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to peptidoglycan (GO:0071224) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to calcium ion (GO:1905945) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to lipoteichoic acid (GO:0071223) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to lipopolysaccharide (GO:0071222) 197 0 .06 - < 0.01 1.00E00 1.00E00 cellular response to bacterial lipopeptide (GO:0071221) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to bacterial lipoprotein (GO:0071220) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gonad development (GO:1905941) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gonad development (GO:1905940) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of localization in cell (GO:0051649) 1639 0 .48 - < 0.01 1.00E00 1.00E00 mitochondrial NAD transmembrane transport (GO:1990549) 2 0 .00 - < 0.01 1.00E00 1.00E00 vesicle localization (GO:0051648) 189 0 .06 - < 0.01 1.00E00 1.00E00 mitochondrial FAD transmembrane transport (GO:1990548) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleus localization (GO:0051647) 33 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial phosphate ion transmembrane transport (GO:1990547) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion localization (GO:0051646) 53 0 .02 - < 0.01 1.00E00 1.00E00 mitochondrial tricarboxylic acid transmembrane transport (GO:1990546) 1 0 .00 - < 0.01 1.00E00 1.00E00 Golgi localization (GO:0051645) 14 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial ATP transmembrane transport (GO:1990544) 8 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum localization (GO:0051643) 9 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial S-adenosyl-L-methionine transmembrane transport (GO:1990543) 1 0 .00 - < 0.01 1.00E00 1.00E00 centrosome localization (GO:0051642) 33 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial transmembrane transport (GO:1990542) 98 0 .03 - < 0.01 1.00E00 1.00E00 cellular localization (GO:0051641) 2680 0 .78 - < 0.01 1.00E00 1.00E00 organelle localization (GO:0051640) 547 0 .16 - < 0.01 1.00E00 1.00E00 mitochondrial manganese ion transmembrane transport (GO:1990540) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to molecule of bacterial origin (GO:0071219) 210 0 .06 - < 0.01 1.00E00 1.00E00 cellular response to misfolded protein (GO:0071218) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of gonad development (GO:1905939) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to external biotic stimulus (GO:0071217) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of germ cell proliferation (GO:1905938) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to biotic stimulus (GO:0071216) 236 0 .07 - < 0.01 1.00E00 1.00E00 negative regulation of germ cell proliferation (GO:1905937) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of germ cell proliferation (GO:1905936) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to abiotic stimulus (GO:0071214) 328 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cell fate determination (GO:1905935) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell fate determination (GO:1905934) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell fate determination (GO:1905933) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to vacuole involved in autophagy (GO:0071211) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905932) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905931) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching (GO:1905930) 3 0 .00 - < 0.01 1.00E00 1.00E00 actin filament network formation (GO:0051639) 9 0 .00 - < 0.01 1.00E00 1.00E00 fructose import across plasma membrane (GO:1990539) 1 0 .00 - < 0.01 1.00E00 1.00E00 barbed-end actin filament uncapping (GO:0051638) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection maintenance (GO:1990535) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acetylcholine uptake (GO:0051631) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid derivative biosynthetic process (GO:1901570) 53 0 .02 - < 0.01 1.00E00 1.00E00 acetylcholine uptake (GO:0051630) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to juxtaparanode region of axon (GO:0071206) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to juxtaparanode region of axon (GO:0071205) 4 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid derivative catabolic process (GO:1901569) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CoA-transferase activity (GO:1905920) 6 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid derivative metabolic process (GO:1901568) 78 0 .02 - < 0.01 1.00E00 1.00E00 epinephrine uptake (GO:0051625) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to camptothecin (GO:1901563) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of norepinephrine uptake (GO:0051623) 1 0 .00 - < 0.01 1.00E00 1.00E00 bone regeneration (GO:1990523) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of norepinephrine uptake (GO:0051622) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of norepinephrine uptake (GO:0051621) 2 0 .00 - < 0.01 1.00E00 1.00E00 norepinephrine uptake (GO:0051620) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell differentiation involved in phenotypic switching (GO:1905917) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell differentiation involved in phenotypic switching (GO:1905916) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell differentiation involved in phenotypic switching (GO:1905915) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion export across plasma membrane (GO:1905913) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion export across plasma membrane (GO:1905912) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to metformin (GO:1901558) 2 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide import into mitochondrion (GO:1990519) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to fenofibrate (GO:1901557) 2 0 .00 - < 0.01 1.00E00 1.00E00 histamine uptake (GO:0051615) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell development (GO:1901552) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of serotonin uptake (GO:0051612) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell development (GO:1901551) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of serotonin uptake (GO:0051611) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell development (GO:1901550) 17 0 .00 - < 0.01 1.00E00 1.00E00 serotonin uptake (GO:0051610) 9 0 .00 - < 0.01 1.00E00 1.00E00 replicative senescence (GO:0090399) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular senescence (GO:0090398) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of excitatory postsynaptic potential (GO:0090394) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amyloid fibril formation (GO:1905908) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid fibril formation (GO:1905907) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amyloid fibril formation (GO:1905906) 19 0 .01 - < 0.01 1.00E00 1.00E00 histamine transport (GO:0051608) 10 0 .00 - < 0.01 1.00E00 1.00E00 defense response to virus (GO:0051607) 283 0 .08 - < 0.01 1.00E00 1.00E00 detection of stimulus (GO:0051606) 686 0 .20 - < 0.01 1.00E00 1.00E00 response to raffinose (GO:1901545) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA-templated DNA replication (GO:1990506) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication maintenance of fidelity (GO:1990505) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein maturation (GO:0051604) 538 0 .16 - < 0.01 1.00E00 1.00E00 dense core granule exocytosis (GO:1990504) 9 0 .00 - < 0.01 1.00E00 1.00E00 proteolysis involved in protein catabolic process (GO:0051603) 669 0 .20 - < 0.01 1.00E00 1.00E00 response to electrical stimulus (GO:0051602) 45 0 .01 - < 0.01 1.00E00 1.00E00 dense core granule maturation (GO:1990502) 3 0 .00 - < 0.01 1.00E00 1.00E00 exocyst localization (GO:0051601) 4 0 .00 - < 0.01 1.00E00 1.00E00 phagosome-lysosome fusion involved in apoptotic cell clearance (GO:0090389) 1 0 .00 - < 0.01 1.00E00 1.00E00 phagolysosome assembly involved in apoptotic cell clearance (GO:0090387) 1 0 .00 - < 0.01 1.00E00 1.00E00 phagosome maturation involved in apoptotic cell clearance (GO:0090386) 1 0 .00 - < 0.01 1.00E00 1.00E00 phagosome-lysosome fusion (GO:0090385) 14 0 .00 - < 0.01 1.00E00 1.00E00 phagosome-lysosome docking (GO:0090384) 1 0 .00 - < 0.01 1.00E00 1.00E00 phagosome acidification (GO:0090383) 7 0 .00 - < 0.01 1.00E00 1.00E00 phagosome maturation (GO:0090382) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of hematopoietic progenitor cell differentiation (GO:1901534) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hematopoietic progenitor cell differentiation (GO:1901533) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hematopoietic progenitor cell differentiation (GO:1901532) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol efflux (GO:0090370) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anion channel activity (GO:1901529) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitophagy (GO:1901526) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of mitophagy (GO:1901525) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitophagy (GO:1901524) 48 0 .01 - < 0.01 1.00E00 1.00E00 icosanoid catabolic process (GO:1901523) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ornithine metabolic process (GO:0090368) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA modification (GO:0090367) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA modification (GO:0090365) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proteasome assembly (GO:0090364) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of platelet-derived growth factor production (GO:0090362) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor production (GO:0090361) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylserine exposure on apoptotic cell surface (GO:0070782) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to biotin (GO:0070781) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of L-tryptophan metabolic process (GO:0090357) 1 0 .00 - < 0.01 1.00E00 1.00E00 efferent axon development in a lateral line nerve (GO:0048894) 1 0 .00 - < 0.01 1.00E00 1.00E00 lateral line nerve development (GO:0048892) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of organofluorine metabolic process (GO:0090350) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-aspartate import across plasma membrane (GO:0070779) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-aspartate transmembrane transport (GO:0070778) 11 0 .00 - < 0.01 1.00E00 1.00E00 D-aspartate transmembrane transport (GO:0070777) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial tube morphogenesis (GO:1901509) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of acylglycerol transport (GO:1901508) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acylglycerol transport (GO:1901506) 3 0 .00 - < 0.01 1.00E00 1.00E00 ether biosynthetic process (GO:1901503) 13 0 .00 - < 0.01 1.00E00 1.00E00 ether catabolic process (GO:1901502) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of organohalogen metabolic process (GO:0090349) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuromast hair cell differentiation (GO:0048886) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of organofluorine metabolic process (GO:0090348) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of organohalogen metabolic process (GO:0090347) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuromast development (GO:0048884) 2 0 .00 - < 0.01 1.00E00 1.00E00 organofluorine metabolic process (GO:0090346) 1 0 .00 - < 0.01 1.00E00 1.00E00 organohalogen metabolic process (GO:0090345) 2 0 .00 - < 0.01 1.00E00 1.00E00 lateral line development (GO:0048882) 2 0 .00 - < 0.01 1.00E00 1.00E00 mechanosensory lateral line system development (GO:0048881) 1 0 .00 - < 0.01 1.00E00 1.00E00 sensory system development (GO:0048880) 417 0 .12 - < 0.01 1.00E00 1.00E00 negative regulation of secretion of lysosomal enzymes (GO:0090341) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secretion of lysosomal enzymes (GO:0090340) 1 0 .00 - < 0.01 1.00E00 1.00E00 chemical homeostasis (GO:0048878) 913 0 .27 - < 0.01 1.00E00 1.00E00 homeostasis of number of retina cells (GO:0048877) 3 0 .00 - < 0.01 1.00E00 1.00E00 host-mediated regulation of intestinal microbiota composition (GO:0048874) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of brown fat cell differentiation (GO:0090336) 16 0 .00 - < 0.01 1.00E00 1.00E00 homeostasis of number of cells within a tissue (GO:0048873) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of brown fat cell differentiation (GO:0090335) 24 0 .01 - < 0.01 1.00E00 1.00E00 homeostasis of number of cells (GO:0048872) 298 0 .09 - < 0.01 1.00E00 1.00E00 multicellular organismal-level homeostasis (GO:0048871) 645 0 .19 - < 0.01 1.00E00 1.00E00 cell motility (GO:0048870) 1163 0 .34 - < 0.01 1.00E00 1.00E00 negative regulation of platelet aggregation (GO:0090331) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of platelet aggregation (GO:0090330) 30 0 .01 - < 0.01 1.00E00 1.00E00 interleukin-35-mediated signaling pathway (GO:0070757) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular developmental process (GO:0048869) 3714 0 1.08 - < 0.01 6.00E-01 1.00E00 regulation of DNA-templated DNA replication (GO:0090329) 41 0 .01 - < 0.01 1.00E00 1.00E00 stem cell fate specification (GO:0048866) 6 0 .00 - < 0.01 1.00E00 1.00E00 stem cell fate commitment (GO:0048865) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of locomotion involved in locomotory behavior (GO:0090327) 3 0 .00 - < 0.01 1.00E00 1.00E00 stem cell development (GO:0048864) 85 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of locomotion involved in locomotory behavior (GO:0090326) 2 0 .00 - < 0.01 1.00E00 1.00E00 stem cell differentiation (GO:0048863) 190 0 .06 - < 0.01 1.00E00 1.00E00 regulation of locomotion involved in locomotory behavior (GO:0090325) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative phosphorylation (GO:0090324) 8 0 .00 - < 0.01 1.00E00 1.00E00 leukemia inhibitory factor signaling pathway (GO:0048861) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of superoxide metabolic process (GO:0090322) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of chylomicron remnant clearance (GO:0090321) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chylomicron remnant clearance (GO:0090320) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-6 (GO:0070741) 32 0 .01 - < 0.01 1.00E00 1.00E00 formation of anatomical boundary (GO:0048859) 7 0 .00 - < 0.01 1.00E00 1.00E00 cell projection morphogenesis (GO:0048858) 512 0 .15 - < 0.01 1.00E00 1.00E00 neural nucleus development (GO:0048857) 69 0 .02 - < 0.01 1.00E00 1.00E00 anatomical structure development (GO:0048856) 5272 3 1.54 + 1.95 1.79E-01 1.00E00 negative regulation of intracellular protein transport (GO:0090317) 35 0 .01 - < 0.01 1.00E00 1.00E00 brain morphogenesis (GO:0048854) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular protein transport (GO:0090316) 93 0 .03 - < 0.01 1.00E00 1.00E00 forebrain morphogenesis (GO:0048853) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein targeting to membrane (GO:0090315) 6 0 .00 - < 0.01 1.00E00 1.00E00 diencephalon morphogenesis (GO:0048852) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein targeting to membrane (GO:0090314) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein targeting to membrane (GO:0090313) 32 0 .01 - < 0.01 1.00E00 1.00E00 hypophysis morphogenesis (GO:0048850) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein deacetylation (GO:0090312) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein deacetylation (GO:0090311) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA methylation-dependent heterochromatin formation (GO:0090310) 2 0 .00 - < 0.01 1.00E00 1.00E00 cGMP transport (GO:0070731) 1 0 .00 - < 0.01 1.00E00 1.00E00 cAMP transport (GO:0070730) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ribonucleoprotein complex localization (GO:2000199) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ribonucleoprotein complex localization (GO:2000198) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ribonucleoprotein complex localization (GO:2000197) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of female gonad development (GO:2000196) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of female gonad development (GO:2000195) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of female gonad development (GO:2000194) 7 0 .00 - < 0.01 1.00E00 1.00E00 ammonium import across plasma membrane (GO:0140157) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fatty acid transport (GO:2000193) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid transport (GO:2000192) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fatty acid transport (GO:2000191) 34 0 .01 - < 0.01 1.00E00 1.00E00 axon extension involved in axon guidance (GO:0048846) 11 0 .00 - < 0.01 1.00E00 1.00E00 venous blood vessel morphogenesis (GO:0048845) 9 0 .00 - < 0.01 1.00E00 1.00E00 mitotic spindle assembly (GO:0090307) 52 0 .02 - < 0.01 1.00E00 1.00E00 artery morphogenesis (GO:0048844) 69 0 .02 - < 0.01 1.00E00 1.00E00 meiotic spindle assembly (GO:0090306) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of axon extension involved in axon guidance (GO:0048843) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of axon extension involved in axon guidance (GO:0048842) 7 0 .00 - < 0.01 1.00E00 1.00E00 nucleic acid metabolic process (GO:0090304) 2164 0 .63 - < 0.01 1.00E00 1.00E00 regulation of axon extension involved in axon guidance (GO:0048841) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of wound healing (GO:0090303) 63 0 .02 - < 0.01 1.00E00 1.00E00 otolith development (GO:0048840) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neural crest formation (GO:0090301) 1 0 .00 - < 0.01 1.00E00 1.00E00 cyclic nucleotide transport (GO:0070729) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular macromolecule localization (GO:0070727) 1972 0 .57 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor internalization (GO:0099590) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to cholesterol (GO:0070723) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of phosphate transmembrane transport (GO:2000187) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphate transmembrane transport (GO:2000186) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphate transmembrane transport (GO:2000185) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of progesterone biosynthetic process (GO:2000184) 1 0 .00 - < 0.01 1.00E00 1.00E00 inner ear development (GO:0048839) 203 0 .06 - < 0.01 1.00E00 1.00E00 regulation of progesterone biosynthetic process (GO:2000182) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel morphogenesis (GO:2000181) 110 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of androgen biosynthetic process (GO:2000180) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial potassium ion transmembrane transport (GO:0140141) 4 0 .00 - < 0.01 1.00E00 1.00E00 inorganic ion import across plasma membrane (GO:0099587) 108 0 .03 - < 0.01 1.00E00 1.00E00 mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication (GO:0070716) 2 0 .00 - < 0.01 1.00E00 1.00E00 sodium-dependent organic cation transport (GO:0070715) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neural precursor cell proliferation (GO:2000179) 54 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0106289) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neural precursor cell proliferation (GO:2000178) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0106288) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neural precursor cell proliferation (GO:2000177) 92 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of pro-T cell differentiation (GO:2000176) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pro-T cell differentiation (GO:2000174) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of branching morphogenesis of a nerve (GO:2000173) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching morphogenesis of a nerve (GO:2000172) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendrite development (GO:2000171) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-cysteine S-nitrosylation (GO:2000170) 1 0 .00 - < 0.01 1.00E00 1.00E00 formation of extrachromosomal circular DNA (GO:0001325) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte chemotaxis (GO:0140131) 19 0 .01 - < 0.01 1.00E00 1.00E00 enucleate erythrocyte development (GO:0048822) 6 0 .00 - < 0.01 1.00E00 1.00E00 erythrocyte development (GO:0048821) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of translation at postsynapse, modulating synaptic transmission (GO:0099578) 3 0 .00 - < 0.01 1.00E00 1.00E00 hair follicle maturation (GO:0048820) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation at presynapse, modulating synaptic transmission (GO:0099577) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process at postsynapse, modulating synaptic transmission (GO:0099576) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process at presynapse, modulating synaptic transmission (GO:0099575) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of peptidoglycan (GO:0032499) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of muramyl dipeptide (GO:0032498) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of lipopolysaccharide (GO:0032497) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to lipopolysaccharide (GO:0032496) 323 0 .09 - < 0.01 1.00E00 1.00E00 response to muramyl dipeptide (GO:0032495) 21 0 .01 - < 0.01 1.00E00 1.00E00 response to peptidoglycan (GO:0032494) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to bacterial lipoprotein (GO:0032493) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-cysteine S-nitrosylation (GO:2000169) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of UDP-N-acetylglucosamine biosynthetic process (GO:0106279) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of molecule of fungal origin (GO:0032491) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of UDP-N-acetylglucosamine biosynthetic process (GO:0106278) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of molecule of bacterial origin (GO:0032490) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hair follicle maturation (GO:0048819) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hair follicle maturation (GO:0048818) 5 0 .00 - < 0.01 1.00E00 1.00E00 cytosol to ERGIC protein transport (GO:0106273) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hair follicle maturation (GO:0048817) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to ERGIC (GO:0106272) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Lewy body formation (GO:0140123) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendrite morphogenesis (GO:0048814) 64 0 .02 - < 0.01 1.00E00 1.00E00 regulation of Lewy body formation (GO:0140122) 1 0 .00 - < 0.01 1.00E00 1.00E00 dendrite morphogenesis (GO:0048813) 66 0 .02 - < 0.01 1.00E00 1.00E00 neuron projection morphogenesis (GO:0048812) 500 0 .15 - < 0.01 1.00E00 1.00E00 motile cilium assembly (GO:0044458) 82 0 .02 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic cytosolic calcium ion concentration (GO:0099566) 9 0 .00 - < 0.01 1.00E00 1.00E00 chemical synaptic transmission, postsynaptic (GO:0099565) 76 0 .02 - < 0.01 1.00E00 1.00E00 modification of synaptic structure (GO:0099563) 18 0 .01 - < 0.01 1.00E00 1.00E00 maintenance of postsynaptic density structure (GO:0099562) 7 0 .00 - < 0.01 1.00E00 1.00E00 synaptic membrane adhesion (GO:0099560) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of Cdc42 protein signal transduction (GO:0032489) 8 0 .00 - < 0.01 1.00E00 1.00E00 Cdc42 protein signal transduction (GO:0032488) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Rap protein signal transduction (GO:0032487) 3 0 .00 - < 0.01 1.00E00 1.00E00 Rap protein signal transduction (GO:0032486) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Ral protein signal transduction (GO:0032485) 2 0 .00 - < 0.01 1.00E00 1.00E00 Ral protein signal transduction (GO:0032484) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Rab protein signal transduction (GO:0032483) 7 0 .00 - < 0.01 1.00E00 1.00E00 Rab protein signal transduction (GO:0032482) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin-specific protease activity (GO:2000158) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type I interferon production (GO:0032481) 76 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin-specific protease activity (GO:2000157) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type I interferon production (GO:0032480) 45 0 .01 - < 0.01 1.00E00 1.00E00 regulation of retrograde vesicle-mediated transport, Golgi to ER (GO:2000156) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cilium-dependent cell motility (GO:2000155) 15 0 .00 - < 0.01 1.00E00 1.00E00 male genitalia morphogenesis (GO:0048808) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-specific protease activity (GO:2000152) 3 0 .00 - < 0.01 1.00E00 1.00E00 female genitalia morphogenesis (GO:0048807) 3 0 .00 - < 0.01 1.00E00 1.00E00 export across plasma membrane (GO:0140115) 62 0 .02 - < 0.01 1.00E00 1.00E00 genitalia development (GO:0048806) 48 1 .01 + 71.46 1.39E-02 1.00E00 extracellular vesicle biogenesis (GO:0140112) 9 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of synapse structure (GO:0099558) 30 0 .01 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission (GO:0099557) 1 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by nitric oxide, modulating synaptic transmission (GO:0099555) 1 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by soluble gas, modulating synaptic transmission (GO:0099554) 1 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission (GO:0099553) 2 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by lipid, modulating synaptic transmission (GO:0099552) 2 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling, modulating synaptic transmission (GO:0099550) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type I interferon production (GO:0032479) 127 0 .04 - < 0.01 1.00E00 1.00E00 otolith formation (GO:0032475) 1 0 .00 - < 0.01 1.00E00 1.00E00 otolith morphogenesis (GO:0032474) 5 0 .00 - < 0.01 1.00E00 1.00E00 Golgi calcium ion transport (GO:0032472) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell motility (GO:2000147) 585 0 .17 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum calcium ion concentration (GO:0032470) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell motility (GO:2000146) 312 1 .09 + 10.99 8.76E-02 1.00E00 regulation of cell motility (GO:2000145) 1023 1 .30 + 3.35 2.64E-01 1.00E00 positive regulation of DNA-templated transcription initiation (GO:2000144) 69 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated transcription initiation (GO:2000143) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA-templated transcription initiation (GO:2000142) 82 0 .02 - < 0.01 1.00E00 1.00E00 interleukin-10-mediated signaling pathway (GO:0140105) 12 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-glutamine modification (GO:0018199) 4 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine modification (GO:0018198) 22 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-aspartic acid modification (GO:0018197) 2 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by nitric oxide (GO:0099548) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-arginine modification (GO:0018195) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation at synapse, modulating synaptic transmission (GO:0099547) 6 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-amino acid modification (GO:0018193) 359 0 .10 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by trans-synaptic complex (GO:0099545) 7 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine octanoylation (GO:0018191) 1 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by soluble gas (GO:0099543) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein octanoylation (GO:0018190) 1 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by endocannabinoid (GO:0099542) 5 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by lipid (GO:0099541) 5 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum calcium ion homeostasis (GO:0032469) 27 0 .01 - < 0.01 1.00E00 1.00E00 Golgi calcium ion homeostasis (GO:0032468) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytokinesis (GO:0032467) 50 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cytokinesis (GO:0032466) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytokinesis (GO:0032465) 95 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of protein homooligomerization (GO:0032464) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein homooligomerization (GO:0032463) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein homooligomerization (GO:0032462) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in heart morphogenesis (GO:2000138) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein oligomerization (GO:0032461) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in heart morphogenesis (GO:2000137) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein oligomerization (GO:0032460) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in heart morphogenesis (GO:2000136) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) 58 0 .02 - < 0.01 1.00E00 1.00E00 synaptic signaling via neuropeptide (GO:0099538) 7 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling (GO:0099537) 437 0 .13 - < 0.01 1.00E00 1.00E00 synaptic signaling (GO:0099536) 473 0 .14 - < 0.01 1.00E00 1.00E00 synaptic vesicle endosomal processing (GO:0099532) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein oligomerization (GO:0032459) 8 0 .00 - < 0.01 1.00E00 1.00E00 slow endocytic recycling (GO:0032458) 2 0 .00 - < 0.01 1.00E00 1.00E00 endocytic recycling (GO:0032456) 78 0 .02 - < 0.01 1.00E00 1.00E00 regulation of endocannabinoid signaling pathway (GO:2000124) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of removal of superoxide radicals (GO:2000121) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sodium-dependent phosphate transport (GO:2000120) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein depropionylation (GO:0106230) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein nucleotidylation (GO:0018175) 2 0 .00 - < 0.01 1.00E00 1.00E00 biological process involved in interspecies interaction between organisms (GO:0044419) 1596 0 .47 - < 0.01 1.00E00 1.00E00 postsynapse to nucleus signaling pathway (GO:0099527) 4 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic dense core vesicle exocytosis (GO:0099525) 4 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine oxidation (GO:0018171) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein urmylation (GO:0032447) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein modification by small protein conjugation (GO:0032446) 671 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of sodium-dependent phosphate transport (GO:2000119) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sodium-dependent phosphate transport (GO:2000118) 5 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine glutarylation (GO:0106227) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of cell polarity (GO:2000114) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage apoptotic process (GO:2000111) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage apoptotic process (GO:2000110) 7 0 .00 - < 0.01 1.00E00 1.00E00 dense core granule cytoskeletal transport (GO:0099519) 9 0 .00 - < 0.01 1.00E00 1.00E00 vesicle cytoskeletal trafficking (GO:0099518) 56 0 .02 - < 0.01 1.00E00 1.00E00 symbiont entry into host (GO:0044409) 114 0 .03 - < 0.01 1.00E00 1.00E00 synaptic vesicle transport along microtubule (GO:0099517) 17 0 .00 - < 0.01 1.00E00 1.00E00 actin filament-based transport (GO:0099515) 8 0 .00 - < 0.01 1.00E00 1.00E00 adhesion of symbiont to host (GO:0044406) 11 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle cytoskeletal transport (GO:0099514) 17 0 .00 - < 0.01 1.00E00 1.00E00 biological process involved in symbiotic interaction (GO:0044403) 186 0 .05 - < 0.01 1.00E00 1.00E00 cAMP catabolic process (GO:0006198) 9 0 .00 - < 0.01 1.00E00 1.00E00 AMP catabolic process (GO:0006196) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleotide catabolic process (GO:0006195) 90 0 .03 - < 0.01 1.00E00 1.00E00 melanosome organization (GO:0032438) 38 0 .01 - < 0.01 1.00E00 1.00E00 ITP catabolic process (GO:0006193) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032436) 81 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032435) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of proteasomal ubiquitin-dependent protein catabolic process (GO:0032434) 131 0 .04 - < 0.01 1.00E00 1.00E00 regulation of macrophage apoptotic process (GO:2000109) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte apoptotic process (GO:2000108) 29 0 .01 - < 0.01 1.00E00 1.00E00 activation of phospholipase A2 activity (GO:0032431) 1 0 .00 - < 0.01 1.00E00 1.00E00 thermosensory behavior (GO:0040040) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte apoptotic process (GO:2000107) 57 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipase A2 activity (GO:0032430) 4 0 .00 - < 0.01 1.00E00 1.00E00 tRNA C3-cytosine methylation (GO:0106217) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte apoptotic process (GO:2000106) 92 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated DNA replication (GO:2000105) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated DNA replication (GO:2000104) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mammary stem cell proliferation (GO:2000103) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mammary stem cell proliferation (GO:2000101) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein oxidation (GO:0018158) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of presynaptic cytosolic calcium ion concentration (GO:0099509) 15 0 .00 - < 0.01 1.00E00 1.00E00 symbiont-mediated disruption of host cellular anatomical structure (GO:0052008) 4 0 .00 - < 0.01 1.00E00 1.00E00 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine (GO:0018153) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of presynaptic membrane potential (GO:0099505) 31 0 .01 - < 0.01 1.00E00 1.00E00 synaptic vesicle cycle (GO:0099504) 150 0 .04 - < 0.01 1.00E00 1.00E00 calcium-dependent activation of synaptic vesicle fusion (GO:0099502) 13 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' IMP biosynthetic process (GO:0006189) 6 0 .00 - < 0.01 1.00E00 1.00E00 IMP biosynthetic process (GO:0006188) 11 0 .00 - < 0.01 1.00E00 1.00E00 vesicle fusion to plasma membrane (GO:0099500) 11 0 .00 - < 0.01 1.00E00 1.00E00 dGDP biosynthetic process (GO:0006185) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipase A2 activity (GO:0032429) 7 0 .00 - < 0.01 1.00E00 1.00E00 polar body extrusion after meiotic divisions (GO:0040038) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037) 19 0 .01 - < 0.01 1.00E00 1.00E00 GTP biosynthetic process (GO:0006183) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor receptor signaling pathway (GO:0040036) 34 0 .01 - < 0.01 1.00E00 1.00E00 cGMP biosynthetic process (GO:0006182) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mismatch repair (GO:0032425) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of development, heterochronic (GO:0040034) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mismatch repair (GO:0032423) 4 0 .00 - < 0.01 1.00E00 1.00E00 snRNA modification (GO:0040031) 7 0 .00 - < 0.01 1.00E00 1.00E00 peptide cross-linking (GO:0018149) 22 0 .01 - < 0.01 1.00E00 1.00E00 keratan sulfate proteoglycan biosynthetic process (GO:0018146) 16 0 .00 - < 0.01 1.00E00 1.00E00 guanine salvage (GO:0006178) 1 0 .00 - < 0.01 1.00E00 1.00E00 GMP biosynthetic process (GO:0006177) 14 0 .00 - < 0.01 1.00E00 1.00E00 epigenetic regulation of gene expression (GO:0040029) 278 0 .08 - < 0.01 1.00E00 1.00E00 dATP biosynthetic process (GO:0006175) 1 0 .00 - < 0.01 1.00E00 1.00E00 lysosome localization (GO:0032418) 62 0 .02 - < 0.01 1.00E00 1.00E00 dADP biosynthetic process (GO:0006173) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sodium:proton antiporter activity (GO:0032417) 3 0 .00 - < 0.01 1.00E00 1.00E00 ADP biosynthetic process (GO:0006172) 6 0 .00 - < 0.01 1.00E00 1.00E00 cAMP biosynthetic process (GO:0006171) 10 0 .00 - < 0.01 1.00E00 1.00E00 dAMP biosynthetic process (GO:0006170) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ion transmembrane transporter activity (GO:0032414) 59 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of ion transmembrane transporter activity (GO:0032413) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of monoatomic ion transmembrane transporter activity (GO:0032412) 138 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of transporter activity (GO:0032411) 65 0 .02 - < 0.01 1.00E00 1.00E00 regulation of meiotic nuclear division (GO:0040020) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of transporter activity (GO:0032410) 48 0 .01 - < 0.01 1.00E00 1.00E00 adenine salvage (GO:0006168) 1 0 .00 - < 0.01 1.00E00 1.00E00 AMP biosynthetic process (GO:0006167) 13 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside salvage (GO:0006166) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of embryonic development (GO:0040019) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of transporter activity (GO:0032409) 154 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of multicellular organism growth (GO:0040018) 31 0 .01 - < 0.01 1.00E00 1.00E00 purine nucleotide biosynthetic process (GO:0006164) 179 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of locomotion (GO:0040017) 601 0 .18 - < 0.01 1.00E00 1.00E00 purine nucleotide metabolic process (GO:0006163) 377 0 .11 - < 0.01 1.00E00 1.00E00 embryonic cleavage (GO:0040016) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of multicellular organism growth (GO:0040015) 13 0 .00 - < 0.01 1.00E00 1.00E00 deoxyguanosine catabolic process (GO:0006161) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of multicellular organism growth (GO:0040014) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of locomotion (GO:0040013) 330 1 .10 + 10.39 9.24E-02 1.00E00 regulation of locomotion (GO:0040012) 1067 1 .31 + 3.21 2.73E-01 1.00E00 melanosome transport (GO:0032402) 20 0 .01 - < 0.01 1.00E00 1.00E00 locomotion (GO:0040011) 367 0 .11 - < 0.01 1.00E00 1.00E00 establishment of melanosome localization (GO:0032401) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of growth rate (GO:0040010) 3 0 .00 - < 0.01 1.00E00 1.00E00 melanosome localization (GO:0032400) 23 0 .01 - < 0.01 1.00E00 1.00E00 protein hydroxylation (GO:0018126) 18 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine methylation (GO:0018125) 1 0 .00 - < 0.01 1.00E00 1.00E00 deoxyadenosine catabolic process (GO:0006157) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of growth rate (GO:0040009) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of growth (GO:0040008) 595 0 .17 - < 0.01 1.00E00 1.00E00 adenosine catabolic process (GO:0006154) 4 0 .00 - < 0.01 1.00E00 1.00E00 growth (GO:0040007) 443 1 .13 + 7.74 1.22E-01 1.00E00 purine nucleoside catabolic process (GO:0006152) 8 0 .00 - < 0.01 1.00E00 1.00E00 establishment of mitotic spindle localization (GO:0040001) 42 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine S-nitrosylation (GO:0018119) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle tissue development (GO:1905899) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein adenylylation (GO:0018117) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of response to endoplasmic reticulum stress (GO:1905898) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of response to endoplasmic reticulum stress (GO:1905897) 92 0 .03 - < 0.01 1.00E00 1.00E00 mitotic spindle checkpoint signaling (GO:0071174) 30 0 .01 - < 0.01 1.00E00 1.00E00 spindle assembly checkpoint signaling (GO:0071173) 30 0 .01 - < 0.01 1.00E00 1.00E00 deoxyinosine catabolic process (GO:0006149) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to very-low-density lipoprotein particle stimulus (GO:1905890) 1 0 .00 - < 0.01 1.00E00 1.00E00 inosine catabolic process (GO:0006148) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to hydrostatic pressure (GO:0051599) 7 0 .00 - < 0.01 1.00E00 1.00E00 guanine catabolic process (GO:0006147) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic recombination checkpoint signaling (GO:0051598) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to methylmercury (GO:0051597) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translation in response to stress (GO:1990497) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase catabolic process (GO:0006145) 3 0 .00 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process (GO:0051596) 4 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase metabolic process (GO:0006144) 19 0 .01 - < 0.01 1.00E00 1.00E00 response to methylglyoxal (GO:0051595) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to folic acid (GO:0051593) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to calcium ion (GO:0051592) 137 0 .04 - < 0.01 1.00E00 1.00E00 regulation of nucleotide metabolic process (GO:0006140) 86 0 .03 - < 0.01 1.00E00 1.00E00 response to cAMP (GO:0051591) 92 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of neurotransmitter transport (GO:0051590) 24 0 .01 - < 0.01 1.00E00 1.00E00 viral translational termination-reinitiation (GO:0075525) 5 0 .00 - < 0.01 1.00E00 1.00E00 viral translational frameshifting (GO:0075523) 21 0 .01 - < 0.01 1.00E00 1.00E00 IRES-dependent viral translational initiation (GO:0075522) 11 0 .00 - < 0.01 1.00E00 1.00E00 microtubule-dependent intracellular transport of viral material towards nucleus (GO:0075521) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to chromatin (GO:0071169) 9 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine phosphorylation (GO:0018108) 58 0 .02 - < 0.01 1.00E00 1.00E00 protein localization to chromatin (GO:0071168) 37 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-threonine phosphorylation (GO:0018107) 37 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleoprotein complex localization (GO:0071166) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine phosphorylation (GO:0018105) 71 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride transport (GO:1905885) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein C-linked glycosylation (GO:0018103) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA replication preinitiation complex assembly (GO:0071163) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of triglyceride transport (GO:1905883) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase-containing compound metabolic process (GO:0006139) 2736 0 .80 - < 0.01 1.00E00 1.00E00 negative regulation of neurotransmitter transport (GO:0051589) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter transport (GO:0051588) 103 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine uptake involved in synaptic transmission (GO:0051586) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopamine uptake involved in synaptic transmission (GO:0051585) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dopamine uptake involved in synaptic transmission (GO:0051584) 8 0 .00 - < 0.01 1.00E00 1.00E00 dopamine uptake involved in synaptic transmission (GO:0051583) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurotransmitter uptake (GO:0051582) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neurotransmitter uptake (GO:0051581) 3 0 .00 - < 0.01 1.00E00 1.00E00 mRNA pseudouridine synthesis (GO:1990481) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter uptake (GO:0051580) 20 0 .01 - < 0.01 1.00E00 1.00E00 microtubule-dependent intracellular transport of viral material (GO:0075519) 1 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-dependent endocytosis of virus by host cell (GO:0075512) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oogenesis (GO:1905879) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of postsynaptic density organization (GO:1905875) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic density organization (GO:1905874) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cell leading edge (GO:1905872) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell leading edge (GO:1905871) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of 3'-UTR-mediated mRNA stabilization (GO:1905870) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of arginine metabolic process (GO:0000821) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate shuttle (GO:0006127) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to ultrasound (GO:1990478) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamine family amino acid metabolic process (GO:0000820) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, cytochrome c to oxygen (GO:0006123) 22 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, ubiquinol to cytochrome c (GO:0006122) 14 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, succinate to ubiquinone (GO:0006121) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial electron transport, NADH to ubiquinone (GO:0006120) 47 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid beta-oxidation (GO:0031999) 6 0 .00 - < 0.01 1.00E00 1.00E00 endocytosis involved in viral entry into host cell (GO:0075509) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fatty acid beta-oxidation (GO:0031998) 20 0 .01 - < 0.01 1.00E00 1.00E00 entry of viral genome into host nucleus through nuclear pore complex via importin (GO:0075506) 2 0 .00 - < 0.01 1.00E00 1.00E00 mRNA export from nucleus in response to heat stress (GO:0031990) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of 3'-UTR-mediated mRNA stabilization (GO:1905869) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of 3'-UTR-mediated mRNA stabilization (GO:1905868) 9 0 .00 - < 0.01 1.00E00 1.00E00 epididymis development (GO:1905867) 5 0 .00 - < 0.01 1.00E00 1.00E00 sister chromatid segregation (GO:0000819) 147 0 .04 - < 0.01 1.00E00 1.00E00 resolution of mitotic recombination intermediates (GO:0071140) 2 0 .00 - < 0.01 1.00E00 1.00E00 oxidative phosphorylation (GO:0006119) 117 0 .03 - < 0.01 1.00E00 1.00E00 NADH oxidation (GO:0006116) 14 0 .00 - < 0.01 1.00E00 1.00E00 protein autosumoylation (GO:1990466) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycerol biosynthetic process (GO:0006114) 5 0 .00 - < 0.01 1.00E00 1.00E00 fermentation (GO:0006113) 3 0 .00 - < 0.01 1.00E00 1.00E00 energy reserve metabolic process (GO:0006112) 77 0 .02 - < 0.01 1.00E00 1.00E00 cellular component maintenance (GO:0043954) 68 0 .02 - < 0.01 1.00E00 1.00E00 smooth endoplasmic reticulum calcium ion homeostasis (GO:0051563) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gluconeogenesis (GO:0006111) 53 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial calcium ion concentration (GO:0051562) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glycolytic process (GO:0006110) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial calcium ion concentration (GO:0051561) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cAMP-mediated signaling (GO:0043951) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial calcium ion homeostasis (GO:0051560) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cAMP-mediated signaling (GO:0043950) 3 0 .00 - < 0.01 1.00E00 1.00E00 bombesin receptor signaling pathway (GO:0031989) 2 0 .00 - < 0.01 1.00E00 1.00E00 locomotion involved in locomotory behavior (GO:0031987) 6 0 .00 - < 0.01 1.00E00 1.00E00 resolution of DNA recombination intermediates (GO:0071139) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pentose-phosphate shunt (GO:1905857) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of pentose-phosphate shunt (GO:1905856) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of carbohydrate metabolic process (GO:0006109) 178 0 .05 - < 0.01 1.00E00 1.00E00 malate metabolic process (GO:0006108) 9 0 .00 - < 0.01 1.00E00 1.00E00 oxaloacetate metabolic process (GO:0006107) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cAMP-mediated signaling (GO:0043949) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to diphenyl ether (GO:1901497) 1 0 .00 - < 0.01 1.00E00 1.00E00 fumarate metabolic process (GO:0006106) 1 0 .00 - < 0.01 1.00E00 1.00E00 succinate metabolic process (GO:0006105) 7 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion-endoplasmic reticulum membrane tethering (GO:1990456) 8 0 .00 - < 0.01 1.00E00 1.00E00 succinyl-CoA metabolic process (GO:0006104) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cysteine metabolic process (GO:1901494) 1 0 .00 - < 0.01 1.00E00 1.00E00 2-oxoglutarate metabolic process (GO:0006103) 18 0 .01 - < 0.01 1.00E00 1.00E00 isocitrate metabolic process (GO:0006102) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphangiogenesis (GO:1901492) 3 0 .00 - < 0.01 1.00E00 1.00E00 citrate metabolic process (GO:0006101) 4 0 .00 - < 0.01 1.00E00 1.00E00 flavone metabolic process (GO:0051552) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lymphangiogenesis (GO:1901491) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphangiogenesis (GO:1901490) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric D-loop disassembly (GO:1905840) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of keratinocyte migration (GO:0051549) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte migration (GO:0051548) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of keratinocyte migration (GO:0051547) 14 0 .00 - < 0.01 1.00E00 1.00E00 keratinocyte migration (GO:0051546) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of elastin biosynthetic process (GO:0051545) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of elastin biosynthetic process (GO:0051543) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-threonine autophosphorylation (GO:1990443) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein-containing complex organization (GO:0043933) 1425 0 .42 - < 0.01 1.00E00 1.00E00 elastin biosynthetic process (GO:0051542) 1 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to nitrosative stress (GO:1990442) 1 0 .00 - < 0.01 1.00E00 1.00E00 ossification involved in bone remodeling (GO:0043932) 3 0 .00 - < 0.01 1.00E00 1.00E00 elastin metabolic process (GO:0051541) 6 0 .00 - < 0.01 1.00E00 1.00E00 ossification involved in bone maturation (GO:0043931) 18 0 .01 - < 0.01 1.00E00 1.00E00 response to corticosteroid (GO:0031960) 159 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric D-loop disassembly (GO:1905839) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomeric D-loop disassembly (GO:1905838) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to pyrimidine ribonucleotide (GO:1905835) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to pyrimidine ribonucleotide (GO:1905834) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule nucleation (GO:1905833) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of spindle assembly (GO:1905832) 8 0 .00 - < 0.01 1.00E00 1.00E00 U6 2'-O-snRNA methylation (GO:1990438) 1 0 .00 - < 0.01 1.00E00 1.00E00 snRNA 2'-O-methylation (GO:1990437) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate transmembrane transport (GO:1901475) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation by host of viral transcription (GO:0043923) 18 0 .01 - < 0.01 1.00E00 1.00E00 siRNA 3'-end processing (GO:1990432) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation by host of viral transcription (GO:0043922) 14 0 .00 - < 0.01 1.00E00 1.00E00 priRNA 3'-end processing (GO:1990431) 2 0 .00 - < 0.01 1.00E00 1.00E00 modulation by host of viral transcription (GO:0043921) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated mineralocorticoid signaling pathway (GO:0031959) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated corticosteroid signaling pathway (GO:0031958) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein autophosphorylation (GO:0031954) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein autophosphorylation (GO:0031953) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein autophosphorylation (GO:0031952) 16 0 .00 - < 0.01 1.00E00 1.00E00 superior temporal gyrus development (GO:0071109) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein K48-linked deubiquitination (GO:0071108) 25 0 .01 - < 0.01 1.00E00 1.00E00 response to parathyroid hormone (GO:0071107) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of prostaglandin catabolic process (GO:1905828) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-11 (GO:0071105) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-9 (GO:0071104) 9 0 .00 - < 0.01 1.00E00 1.00E00 DNA conformation change (GO:0071103) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of chromosome condensation (GO:1905821) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chromosome separation (GO:1905820) 32 0 .01 - < 0.01 1.00E00 1.00E00 miRNA transport (GO:1990428) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tetrapyrrole biosynthetic process (GO:1901465) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitotic recombination-dependent replication fork processing (GO:1990426) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tetrapyrrole biosynthetic process (GO:1901463) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid biosynthetic process (GO:0031948) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid biosynthetic process (GO:0031947) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid biosynthetic process (GO:0031946) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucocorticoid metabolic process (GO:0031945) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glucocorticoid metabolic process (GO:0031944) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucocorticoid metabolic process (GO:0031943) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chromosome separation (GO:1905819) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of chromosome separation (GO:1905818) 77 0 .02 - < 0.01 1.00E00 1.00E00 regulation of excitatory synapse pruning (GO:1905810) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to insulin-like growth factor stimulus (GO:1990418) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to brain-derived neurotrophic factor stimulus (GO:1990416) 10 0 .00 - < 0.01 1.00E00 1.00E00 replication-born double-strand break repair via sister chromatid exchange (GO:1990414) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of biological process involved in symbiotic interaction (GO:0043903) 39 0 .01 - < 0.01 1.00E00 1.00E00 adrenomedullin receptor signaling pathway (GO:1990410) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neural crest formation (GO:0090299) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial DNA replication (GO:0090298) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial DNA replication (GO:0090297) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondria-nucleus signaling pathway (GO:0031930) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial DNA replication (GO:0090296) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synapse organization (GO:1905809) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synapse pruning (GO:1905808) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear matrix anchoring at nuclear membrane (GO:0090292) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synapse pruning (GO:1905806) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of osteoclast proliferation (GO:0090291) 3 0 .00 - < 0.01 1.00E00 1.00E00 excitatory synapse pruning (GO:1905805) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of osteoclast proliferation (GO:0090290) 4 0 .00 - < 0.01 1.00E00 1.00E00 calcitonin gene-related peptide receptor signaling pathway (GO:1990408) 6 0 .00 - < 0.01 1.00E00 1.00E00 adenine nucleotide transport (GO:0051503) 40 0 .01 - < 0.01 1.00E00 1.00E00 embryonic brain development (GO:1990403) 18 0 .01 - < 0.01 1.00E00 1.00E00 embryonic liver development (GO:1990402) 3 0 .00 - < 0.01 1.00E00 1.00E00 embryonic lung development (GO:1990401) 2 0 .00 - < 0.01 1.00E00 1.00E00 TOR signaling (GO:0031929) 43 0 .01 - < 0.01 1.00E00 1.00E00 pyridoxine transport (GO:0031923) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of osteoclast proliferation (GO:0090289) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to growth factor stimulus (GO:0090288) 106 0 .03 - < 0.01 1.00E00 1.00E00 regulation of cellular response to growth factor stimulus (GO:0090287) 324 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion import (GO:0090281) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion import (GO:0090280) 25 0 .01 - < 0.01 1.00E00 1.00E00 vitamin B6 transport (GO:0031919) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic plasticity (GO:0031915) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic plasticity (GO:0031914) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion import (GO:0090279) 45 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of peptide hormone secretion (GO:0090278) 47 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of peptide hormone secretion (GO:0090277) 114 0 .03 - < 0.01 1.00E00 1.00E00 regulation of peptide hormone secretion (GO:0090276) 206 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of somatostatin secretion (GO:0090275) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of somatostatin secretion (GO:0090274) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of somatostatin secretion (GO:0090273) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast growth factor production (GO:0090272) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast growth factor production (GO:0090271) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast growth factor production (GO:0090270) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090267) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of immune complex clearance by monocytes and macrophages (GO:0090265) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of immune complex clearance by monocytes and macrophages (GO:0090264) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of canonical Wnt signaling pathway (GO:0090263) 109 0 .03 - < 0.01 1.00E00 1.00E00 regulation of transcription-coupled nucleotide-excision repair (GO:0090262) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inclusion body assembly (GO:0090261) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of retinal ganglion cell axon guidance (GO:0090260) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to alcohol (GO:1901419) 1 0 .00 - < 0.01 1.00E00 1.00E00 seminal clot liquefaction (GO:0070684) 1 0 .00 - < 0.01 1.00E00 1.00E00 proteasome regulatory particle assembly (GO:0070682) 3 0 .00 - < 0.01 1.00E00 1.00E00 glutaminyl-tRNAGln biosynthesis via transamidation (GO:0070681) 3 0 .00 - < 0.01 1.00E00 1.00E00 animal organ maturation (GO:0048799) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of retinal ganglion cell axon guidance (GO:0090259) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial fission (GO:0090258) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle system process (GO:0090257) 236 0 .07 - < 0.01 1.00E00 1.00E00 pronephros development (GO:0048793) 9 0 .00 - < 0.01 1.00E00 1.00E00 spontaneous exocytosis of neurotransmitter (GO:0048792) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion-regulated exocytosis of neurotransmitter (GO:0048791) 9 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of presynaptic active zone structure (GO:0048790) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein localization involved in establishment of planar polarity (GO:0090251) 2 0 .00 - < 0.01 1.00E00 1.00E00 intralumenal vesicle formation (GO:0070676) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-18 (GO:0070673) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-15 (GO:0070672) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-12 (GO:0070671) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tetrapyrrole metabolic process (GO:1901403) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-4 (GO:0070670) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of tetrapyrrole metabolic process (GO:1901401) 10 0 .00 - < 0.01 1.00E00 1.00E00 cytoskeletal matrix organization at active zone (GO:0048789) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell migration involved in somitogenic axis elongation (GO:0090249) 2 0 .00 - < 0.01 1.00E00 1.00E00 convergent extension involved in somitogenesis (GO:0090246) 1 0 .00 - < 0.01 1.00E00 1.00E00 axis elongation involved in somitogenesis (GO:0090245) 3 0 .00 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in somitogenesis (GO:0090244) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-2 (GO:0070669) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell proliferation (GO:0070668) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell proliferation (GO:0070667) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell proliferation (GO:0070666) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte proliferation (GO:0070665) 166 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte proliferation (GO:0070664) 101 0 .03 - < 0.01 1.00E00 1.00E00 regulation of leukocyte proliferation (GO:0070663) 272 0 .08 - < 0.01 1.00E00 1.00E00 mast cell proliferation (GO:0070662) 4 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte proliferation (GO:0070661) 137 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of arachidonate secretion (GO:0090238) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of arachidonate secretion (GO:0090237) 7 0 .00 - < 0.01 1.00E00 1.00E00 erythrophore differentiation (GO:0048773) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metaphase plate congression (GO:0090235) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of kinetochore assembly (GO:0090234) 3 0 .00 - < 0.01 1.00E00 1.00E00 tissue remodeling (GO:0048771) 112 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of spindle checkpoint (GO:0090233) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of spindle checkpoint (GO:0090232) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spindle checkpoint (GO:0090231) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of centromere complex assembly (GO:0090230) 5 0 .00 - < 0.01 1.00E00 1.00E00 sensory epithelium regeneration (GO:0070654) 1 0 .00 - < 0.01 1.00E00 1.00E00 nonfunctional rRNA decay (GO:0070651) 1 0 .00 - < 0.01 1.00E00 1.00E00 actin filament bundle distribution (GO:0070650) 1 0 .00 - < 0.01 1.00E00 1.00E00 sarcomerogenesis (GO:0048769) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein transport (GO:0140077) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein transport (GO:0140075) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac endothelial to mesenchymal transition (GO:0140074) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation (GO:0048762) 173 0 .05 - < 0.01 1.00E00 1.00E00 regulation of spindle organization (GO:0090224) 48 0 .01 - < 0.01 1.00E00 1.00E00 centrosome-templated microtubule nucleation (GO:0090222) 2 0 .00 - < 0.01 1.00E00 1.00E00 chromosome localization to nuclear envelope involved in homologous chromosome segregation (GO:0090220) 11 0 .00 - < 0.01 1.00E00 1.00E00 formin-nucleated actin cable assembly (GO:0070649) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein modification by small protein conjugation or removal (GO:0070647) 781 0 .23 - < 0.01 1.00E00 1.00E00 protein modification by small protein removal (GO:0070646) 130 0 .04 - < 0.01 1.00E00 1.00E00 vitamin D3 metabolic process (GO:0070640) 8 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine butyrylation (GO:0140067) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine crotonylation (GO:0140066) 1 0 .00 - < 0.01 1.00E00 1.00E00 pigment granule maturation (GO:0048757) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid kinase activity (GO:0090218) 1 0 .00 - < 0.01 1.00E00 1.00E00 branching morphogenesis of a nerve (GO:0048755) 6 0 .00 - < 0.01 1.00E00 1.00E00 branching morphogenesis of an epithelial tube (GO:0048754) 137 0 .04 - < 0.01 1.00E00 1.00E00 pigment granule organization (GO:0048753) 39 0 .01 - < 0.01 1.00E00 1.00E00 semicircular canal morphogenesis (GO:0048752) 8 0 .00 - < 0.01 1.00E00 1.00E00 axon arborization (GO:0140060) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of blood-brain barrier (GO:0090212) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of blood-brain barrier (GO:0090210) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleoside catabolic process (GO:0070638) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyridine nucleoside metabolic process (GO:0070637) 11 0 .00 - < 0.01 1.00E00 1.00E00 transepithelial ammonium transport (GO:0070634) 4 0 .00 - < 0.01 1.00E00 1.00E00 transepithelial transport (GO:0070633) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell-matrix adhesion (GO:2000098) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell-matrix adhesion (GO:2000097) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000096) 9 0 .00 - < 0.01 1.00E00 1.00E00 dendrite arborization (GO:0140059) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) 14 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection arborization (GO:0140058) 22 0 .01 - < 0.01 1.00E00 1.00E00 organelle localization by membrane tethering (GO:0140056) 78 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of triglyceride metabolic process (GO:0090209) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride metabolic process (GO:0090208) 21 0 .01 - < 0.01 1.00E00 1.00E00 smooth muscle tissue development (GO:0048745) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of triglyceride metabolic process (GO:0090207) 40 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial gene expression (GO:0140053) 150 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol metabolic process (GO:0090206) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oxidised low-density lipoprotein particle stimulus (GO:0140052) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle fiber development (GO:0048743) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cholesterol metabolic process (GO:0090205) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of endocardial cushion to mesenchymal transition (GO:0140051) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle fiber development (GO:0048742) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to nuclear pore (GO:0090204) 3 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle fiber development (GO:0048741) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of release of cytochrome c from mitochondria (GO:0090201) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein kinase activity by regulation of protein phosphorylation (GO:0044387) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of release of cytochrome c from mitochondria (GO:0090200) 21 0 .01 - < 0.01 1.00E00 1.00E00 glucose import in response to insulin stimulus (GO:0044381) 6 0 .00 - < 0.01 1.00E00 1.00E00 zymogen granule exocytosis (GO:0070625) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cytoskeleton (GO:0044380) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endocardial cushion to mesenchymal transition (GO:0140049) 1 0 .00 - < 0.01 1.00E00 1.00E00 manganese ion export across plasma membrane (GO:0140048) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue development (GO:0048738) 191 0 .06 - < 0.01 1.00E00 1.00E00 appendage development (GO:0048736) 191 0 .06 - < 0.01 1.00E00 1.00E00 lipid droplet formation (GO:0140042) 15 0 .00 - < 0.01 1.00E00 1.00E00 sebaceous gland development (GO:0048733) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular detoxification of methylglyoxal (GO:0140041) 1 0 .00 - < 0.01 1.00E00 1.00E00 gland development (GO:0048732) 429 1 .13 + 8.00 1.19E-01 1.00E00 system development (GO:0048731) 3614 2 1.05 + 1.90 2.85E-01 1.00E00 epidermis morphogenesis (GO:0048730) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of peroxisome size (GO:0044375) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein processing (GO:0070613) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of type B pancreatic cell development (GO:2000078) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type B pancreatic cell development (GO:2000077) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type B pancreatic cell development (GO:2000074) 9 0 .00 - < 0.01 1.00E00 1.00E00 tissue morphogenesis (GO:0048729) 572 0 .17 - < 0.01 1.00E00 1.00E00 regulation of centromeric sister chromatid cohesion (GO:0070602) 5 0 .00 - < 0.01 1.00E00 1.00E00 centromeric sister chromatid cohesion (GO:0070601) 8 0 .00 - < 0.01 1.00E00 1.00E00 DNA geometric change (GO:0032392) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cortisol biosynthetic process (GO:2000066) 1 0 .00 - < 0.01 1.00E00 1.00E00 exocytic process (GO:0140029) 62 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of cortisol biosynthetic process (GO:2000065) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cortisol biosynthetic process (GO:2000064) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ureter smooth muscle cell differentiation (GO:2000063) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ureter smooth muscle cell differentiation (GO:2000062) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ureter smooth muscle cell differentiation (GO:2000061) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin-dependent protein catabolic process (GO:2000060) 106 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of oligodendrocyte differentiation (GO:0048715) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oligodendrocyte differentiation (GO:0048714) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of oligodendrocyte differentiation (GO:0048713) 45 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial ADP transmembrane transport (GO:0140021) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of astrocyte differentiation (GO:0048712) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of astrocyte differentiation (GO:0048711) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of astrocyte differentiation (GO:0048710) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of rRNA stability (GO:0044357) 1 0 .00 - < 0.01 1.00E00 1.00E00 clearance of foreign intracellular DNA (GO:0044355) 6 0 .00 - < 0.01 1.00E00 1.00E00 macropinocytosis (GO:0044351) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular transport (GO:0032388) 138 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular transport (GO:0032387) 54 0 .02 - < 0.01 1.00E00 1.00E00 regulation of intracellular transport (GO:0032386) 270 0 .08 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular cholesterol transport (GO:0032385) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular cholesterol transport (GO:0032384) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular cholesterol transport (GO:0032383) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin-dependent protein catabolic process (GO:2000059) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular sterol transport (GO:0032382) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-dependent protein catabolic process (GO:2000058) 171 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular sterol transport (GO:0032381) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular sterol transport (GO:0032380) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translational fidelity (GO:0140018) 1 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte differentiation (GO:0048709) 85 0 .02 - < 0.01 1.00E00 1.00E00 astrocyte differentiation (GO:0048708) 68 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of non-canonical Wnt signaling pathway (GO:2000052) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of non-canonical Wnt signaling pathway (GO:2000051) 5 0 .00 - < 0.01 1.00E00 1.00E00 embryonic skeletal system development (GO:0048706) 135 0 .04 - < 0.01 1.00E00 1.00E00 mitotic nuclear division (GO:0140014) 169 0 .05 - < 0.01 1.00E00 1.00E00 regulation of non-canonical Wnt signaling pathway (GO:2000050) 26 0 .01 - < 0.01 1.00E00 1.00E00 skeletal system morphogenesis (GO:0048705) 230 0 .07 - < 0.01 1.00E00 1.00E00 meiotic nuclear division (GO:0140013) 174 0 .05 - < 0.01 1.00E00 1.00E00 embryonic skeletal system morphogenesis (GO:0048704) 96 0 .03 - < 0.01 1.00E00 1.00E00 embryonic viscerocranium morphogenesis (GO:0048703) 10 0 .00 - < 0.01 1.00E00 1.00E00 embryonic neurocranium morphogenesis (GO:0048702) 9 0 .00 - < 0.01 1.00E00 1.00E00 embryonic cranial skeleton morphogenesis (GO:0048701) 45 0 .01 - < 0.01 1.00E00 1.00E00 fibroblast apoptotic process (GO:0044346) 11 0 .00 - < 0.01 1.00E00 1.00E00 stromal-epithelial cell signaling involved in prostate gland development (GO:0044345) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to fibroblast growth factor stimulus (GO:0044344) 131 0 .04 - < 0.01 1.00E00 1.00E00 type B pancreatic cell proliferation (GO:0044342) 17 0 .00 - < 0.01 1.00E00 1.00E00 sodium-dependent phosphate transport (GO:0044341) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular lipid transport (GO:0032379) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular lipid transport (GO:0032378) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular lipid transport (GO:0032377) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cholesterol transport (GO:0032376) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol transport (GO:0032375) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholesterol transport (GO:0032374) 58 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of sterol transport (GO:0032373) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cell-cell adhesion mediated by cadherin (GO:2000049) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sterol transport (GO:0032372) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell-cell adhesion mediated by cadherin (GO:2000048) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sterol transport (GO:0032371) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cell-cell adhesion mediated by cadherin (GO:2000047) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lipid transport (GO:0032370) 87 1 .03 + 39.43 2.51E-02 1.00E00 L-aspartate import across plasma membrane (GO:0140009) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of G1/S transition of mitotic cell cycle (GO:2000045) 151 0 .04 - < 0.01 1.00E00 1.00E00 regulation of cardiac cell fate specification (GO:2000043) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of double-strand break repair via homologous recombination (GO:2000042) 26 0 .01 - < 0.01 1.00E00 1.00E00 morula formation (GO:0140001) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein polyglutamylation (GO:0018095) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein polyglycylation (GO:0018094) 3 0 .00 - < 0.01 1.00E00 1.00E00 canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation (GO:0044338) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell adhesion mediated by cadherin (GO:0044331) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipid transport (GO:0032369) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lipid transport (GO:0032368) 136 1 .04 + 25.22 3.90E-02 1.00E00 intracellular cholesterol transport (GO:0032367) 24 0 .01 - < 0.01 1.00E00 1.00E00 intracellular sterol transport (GO:0032366) 28 0 .01 - < 0.01 1.00E00 1.00E00 intracellular lipid transport (GO:0032365) 41 0 .01 - < 0.01 1.00E00 1.00E00 intracellular oxygen homeostasis (GO:0032364) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyridoxal phosphate catabolic process (GO:0032361) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stem cell population maintenance (GO:2000036) 73 0 .02 - < 0.01 1.00E00 1.00E00 regulation of stem cell division (GO:2000035) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to leptin (GO:0044321) 21 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to leptin stimulus (GO:0044320) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to estradiol (GO:0032355) 120 1 .03 + 28.58 3.45E-02 1.00E00 response to follicle-stimulating hormone (GO:0032354) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hormone biosynthetic process (GO:0032353) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hormone metabolic process (GO:0032352) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hormone metabolic process (GO:0032351) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of animal organ morphogenesis (GO:2000027) 83 0 .02 - < 0.01 1.00E00 1.00E00 regulation of hormone metabolic process (GO:0032350) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glycine import across plasma membrane (GO:1900924) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of multicellular organismal development (GO:2000026) 1400 0 .41 - < 0.01 1.00E00 1.00E00 regulation of glycine import across plasma membrane (GO:1900923) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell contraction (GO:0106135) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell contraction (GO:0106134) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of male gonad development (GO:2000020) 8 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-lysine acetylation (GO:0018076) 3 0 .00 - < 0.01 1.00E00 1.00E00 wound healing, spreading of cells (GO:0044319) 30 0 .01 - < 0.01 1.00E00 1.00E00 protein K27-linked ubiquitination (GO:0044314) 12 0 .00 - < 0.01 1.00E00 1.00E00 protein K6-linked deubiquitination (GO:0044313) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone biosynthetic process (GO:0032349) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of aldosterone biosynthetic process (GO:0032348) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aldosterone biosynthetic process (GO:0032347) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aldosterone metabolic process (GO:0032346) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of aldosterone metabolic process (GO:0032345) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aldosterone metabolic process (GO:0032344) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of male gonad development (GO:2000019) 1 0 .00 - < 0.01 1.00E00 1.00E00 aldosterone biosynthetic process (GO:0032342) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of male gonad development (GO:2000018) 9 0 .00 - < 0.01 1.00E00 1.00E00 aldosterone metabolic process (GO:0032341) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of determination of dorsal identity (GO:2000017) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of determination of dorsal identity (GO:2000016) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of determination of dorsal identity (GO:2000015) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adaxial/abaxial pattern formation (GO:2000011) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cobalamin metabolic process (GO:0106121) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cell surface (GO:2000010) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of sterol biosynthetic process (GO:0106120) 15 0 .00 - < 0.01 1.00E00 1.00E00 cytochrome c-heme linkage (GO:0018063) 1 0 .00 - < 0.01 1.00E00 1.00E00 tricarboxylic acid cycle (GO:0006099) 33 0 .01 - < 0.01 1.00E00 1.00E00 pentose-phosphate shunt (GO:0006098) 14 0 .00 - < 0.01 1.00E00 1.00E00 glyoxylate cycle (GO:0006097) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycolytic process (GO:0006096) 48 0 .01 - < 0.01 1.00E00 1.00E00 gluconeogenesis (GO:0006094) 46 0 .01 - < 0.01 1.00E00 1.00E00 generation of precursor metabolites and energy (GO:0006091) 370 0 .11 - < 0.01 1.00E00 1.00E00 pyruvate metabolic process (GO:0006090) 72 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cell surface (GO:2000009) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chondrocyte differentiation (GO:0032332) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of sterol biosynthetic process (GO:0106119) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell surface (GO:2000008) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of chondrocyte differentiation (GO:0032331) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of sterol biosynthetic process (GO:0106118) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric comma-shaped body morphogenesis (GO:2000007) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chondrocyte differentiation (GO:0032330) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of metanephric comma-shaped body morphogenesis (GO:2000006) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metanephric S-shaped body morphogenesis (GO:2000005) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric S-shaped body morphogenesis (GO:2000004) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA damage checkpoint (GO:2000003) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA damage checkpoint (GO:2000002) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA damage checkpoint (GO:2000001) 23 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-lysine oxidation (GO:0018057) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactate metabolic process (GO:0006089) 16 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate decarboxylation to acetyl-CoA (GO:0006086) 7 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA biosynthetic process (GO:0006085) 14 0 .00 - < 0.01 1.00E00 1.00E00 serine transport (GO:0032329) 10 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA metabolic process (GO:0006084) 29 0 .01 - < 0.01 1.00E00 1.00E00 alanine transport (GO:0032328) 18 0 .01 - < 0.01 1.00E00 1.00E00 acetate metabolic process (GO:0006083) 3 0 .00 - < 0.01 1.00E00 1.00E00 organic acid metabolic process (GO:0006082) 793 0 .23 - < 0.01 1.00E00 1.00E00 aldehyde metabolic process (GO:0006081) 67 0 .02 - < 0.01 1.00E00 1.00E00 molybdopterin cofactor biosynthetic process (GO:0032324) 6 0 .00 - < 0.01 1.00E00 1.00E00 cold-induced thermogenesis (GO:0106106) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamate receptor clustering (GO:0106104) 5 0 .00 - < 0.01 1.00E00 1.00E00 ER-dependent peroxisome localization (GO:0106101) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycerol-3-phosphate metabolic process (GO:0006072) 9 0 .00 - < 0.01 1.00E00 1.00E00 glycerol metabolic process (GO:0006071) 20 0 .01 - < 0.01 1.00E00 1.00E00 prostaglandin secretion (GO:0032310) 5 0 .00 - < 0.01 1.00E00 1.00E00 syncytium formation by plasma membrane fusion (GO:0000768) 38 0 .01 - < 0.01 1.00E00 1.00E00 ethanol catabolic process (GO:0006068) 13 0 .00 - < 0.01 1.00E00 1.00E00 ethanol metabolic process (GO:0006067) 14 0 .00 - < 0.01 1.00E00 1.00E00 alcohol metabolic process (GO:0006066) 314 1 .09 + 10.92 8.81E-02 1.00E00 UDP-glucuronate biosynthetic process (GO:0006065) 2 0 .00 - < 0.01 1.00E00 1.00E00 icosanoid secretion (GO:0032309) 30 0 .01 - < 0.01 1.00E00 1.00E00 glucuronate catabolic process (GO:0006064) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin secretion (GO:0032308) 14 0 .00 - < 0.01 1.00E00 1.00E00 uronic acid metabolic process (GO:0006063) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of prostaglandin secretion (GO:0032307) 1 0 .00 - < 0.01 1.00E00 1.00E00 sorbitol catabolic process (GO:0006062) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of prostaglandin secretion (GO:0032306) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of icosanoid secretion (GO:0032305) 20 0 .01 - < 0.01 1.00E00 1.00E00 sorbitol metabolic process (GO:0006060) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of icosanoid secretion (GO:0032304) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of icosanoid secretion (GO:0032303) 22 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-lysine dimethylation (GO:0018027) 5 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine monomethylation (GO:0018026) 7 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine trimethylation (GO:0018023) 6 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine methylation (GO:0018022) 18 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-histidine methylation (GO:0018021) 1 0 .00 - < 0.01 1.00E00 1.00E00 hexitol metabolic process (GO:0006059) 2 0 .00 - < 0.01 1.00E00 1.00E00 mannoprotein catabolic process (GO:0006058) 4 0 .00 - < 0.01 1.00E00 1.00E00 mannoprotein metabolic process (GO:0006056) 4 0 .00 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate biosynthetic process (GO:0006055) 5 0 .00 - < 0.01 1.00E00 1.00E00 N-acetylneuraminate metabolic process (GO:0006054) 13 0 .00 - < 0.01 1.00E00 1.00E00 N-acetylmannosamine metabolic process (GO:0006051) 2 0 .00 - < 0.01 1.00E00 1.00E00 mannosamine metabolic process (GO:0006050) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intraciliary retrograde transport (GO:1905799) 2 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-proline dimethylation (GO:0018016) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to puromycin (GO:1905795) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glycine methylation (GO:0018013) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid biosynthetic process (GO:0071073) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to puromycin (GO:1905794) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid biosynthetic process (GO:0071072) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to pericentriolar material (GO:1905793) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipid biosynthetic process (GO:0071071) 18 0 .01 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine catabolic process (GO:0006049) 1 0 .00 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine biosynthetic process (GO:0006048) 10 0 .00 - < 0.01 1.00E00 1.00E00 epithelium regeneration (GO:1990399) 1 0 .00 - < 0.01 1.00E00 1.00E00 karyogamy (GO:0000741) 1 0 .00 - < 0.01 1.00E00 1.00E00 UDP-N-acetylglucosamine metabolic process (GO:0006047) 14 0 .00 - < 0.01 1.00E00 1.00E00 N-acetylglucosamine catabolic process (GO:0006046) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stress fiber assembly (GO:0051497) 29 0 .01 - < 0.01 1.00E00 1.00E00 N-acetylglucosamine biosynthetic process (GO:0006045) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of stress fiber assembly (GO:0051496) 51 0 .01 - < 0.01 1.00E00 1.00E00 N-acetylglucosamine metabolic process (GO:0006044) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cytoskeleton organization (GO:0051495) 187 0 .05 - < 0.01 1.00E00 1.00E00 glucosamine catabolic process (GO:0006043) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytoskeleton organization (GO:0051494) 153 0 .04 - < 0.01 1.00E00 1.00E00 regulation of cytoskeleton organization (GO:0051493) 536 0 .16 - < 0.01 1.00E00 1.00E00 glucosamine metabolic process (GO:0006041) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stress fiber assembly (GO:0051492) 91 0 .03 - < 0.01 1.00E00 1.00E00 amino sugar metabolic process (GO:0006040) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of filopodium assembly (GO:0051491) 31 0 .01 - < 0.01 1.00E00 1.00E00 AMPA selective glutamate receptor signaling pathway (GO:0098990) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of filopodium assembly (GO:0051490) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein K33-linked ubiquitination (GO:1990390) 2 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-L-cysteine N-palmitoylation (GO:0018009) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glycine N-myristoylation (GO:0018008) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anaphase-promoting complex-dependent catabolic process (GO:1905786) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine N6-acetylation (GO:0018003) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anaphase-promoting complex-dependent catabolic process (GO:1905784) 5 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glutamic acid acetylation (GO:0018002) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylserine exposure on apoptotic cell surface (GO:1905782) 2 0 .00 - < 0.01 1.00E00 1.00E00 NMDA selective glutamate receptor signaling pathway (GO:0098989) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylserine exposure on apoptotic cell surface (GO:1905780) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand displacement (GO:0000732) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of filopodium assembly (GO:0051489) 49 0 .01 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in DNA repair (GO:0000731) 50 0 .01 - < 0.01 1.00E00 1.00E00 regulation of modification of synapse structure, modulating synaptic transmission (GO:0098987) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA recombinase assembly (GO:0000730) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitotic cleavage furrow ingression (GO:1990386) 1 0 .00 - < 0.01 1.00E00 1.00E00 hyaloid vascular plexus regression (GO:1990384) 7 0 .00 - < 0.01 1.00E00 1.00E00 chitin catabolic process (GO:0006032) 6 0 .00 - < 0.01 1.00E00 1.00E00 chitin metabolic process (GO:0006030) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytosolic calcium ion concentration (GO:0051481) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytosolic calcium ion concentration (GO:0051480) 58 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of exonuclease activity (GO:1905778) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA double-strand break processing (GO:0000729) 20 0 .01 - < 0.01 1.00E00 1.00E00 double-strand break repair via break-induced replication (GO:0000727) 12 0 .00 - < 0.01 1.00E00 1.00E00 recombinational repair (GO:0000725) 125 0 .04 - < 0.01 1.00E00 1.00E00 poly(A)-dependent snoRNA 3'-end processing (GO:0071051) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesodermal cell differentiation (GO:1905772) 2 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair via homologous recombination (GO:0000724) 120 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of mesodermal cell differentiation (GO:1905771) 3 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance (GO:0000723) 99 0 .03 - < 0.01 1.00E00 1.00E00 proteoglycan metabolic process (GO:0006029) 106 0 .03 - < 0.01 1.00E00 1.00E00 regulation of mesodermal cell differentiation (GO:1905770) 8 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance via recombination (GO:0000722) 14 0 .00 - < 0.01 1.00E00 1.00E00 lipid transport across blood-brain barrier (GO:1990379) 5 0 .00 - < 0.01 1.00E00 1.00E00 glycosaminoglycan catabolic process (GO:0006027) 26 0 .01 - < 0.01 1.00E00 1.00E00 inhibitory chemical synaptic transmission (GO:0098977) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine dimer repair by nucleotide-excision repair (GO:0000720) 4 0 .00 - < 0.01 1.00E00 1.00E00 aminoglycan catabolic process (GO:0006026) 32 0 .01 - < 0.01 1.00E00 1.00E00 excitatory chemical synaptic transmission (GO:0098976) 12 0 .00 - < 0.01 1.00E00 1.00E00 glycosaminoglycan biosynthetic process (GO:0006024) 44 0 .01 - < 0.01 1.00E00 1.00E00 postsynaptic actin cytoskeleton organization (GO:0098974) 18 0 .01 - < 0.01 1.00E00 1.00E00 aminoglycan biosynthetic process (GO:0006023) 52 0 .02 - < 0.01 1.00E00 1.00E00 aminoglycan metabolic process (GO:0006022) 93 0 .03 - < 0.01 1.00E00 1.00E00 inositol biosynthetic process (GO:0006021) 3 0 .00 - < 0.01 1.00E00 1.00E00 anterograde dendritic transport of neurotransmitter receptor complex (GO:0098971) 7 0 .00 - < 0.01 1.00E00 1.00E00 inositol metabolic process (GO:0006020) 9 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic neurotransmitter receptor diffusion trapping (GO:0098970) 8 0 .00 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent mRNA catabolic process (GO:0071047) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear histone mRNA catabolic process (GO:0071045) 1 0 .00 - < 0.01 1.00E00 1.00E00 histone mRNA catabolic process (GO:0071044) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protection from non-homologous end joining at telomere (GO:1905765) 3 0 .00 - < 0.01 1.00E00 1.00E00 CUT metabolic process (GO:0071043) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protection from non-homologous end joining at telomere (GO:1905764) 3 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent mRNA catabolic process (GO:0071042) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair, DNA damage recognition (GO:0000715) 1 0 .00 - < 0.01 1.00E00 1.00E00 antisense RNA transcript catabolic process (GO:0071041) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent antisense transcript catabolic process (GO:0071040) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport to postsynaptic membrane (GO:0098969) 11 0 .00 - < 0.01 1.00E00 1.00E00 resolution of meiotic recombination intermediates (GO:0000712) 18 0 .01 - < 0.01 1.00E00 1.00E00 vesicle fusion with vacuole (GO:0051469) 11 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport postsynaptic membrane to endosome (GO:0098968) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA repair synthesis (GO:0000711) 3 0 .00 - < 0.01 1.00E00 1.00E00 exocytic insertion of neurotransmitter receptor to postsynaptic membrane (GO:0098967) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic mismatch repair (GO:0000710) 1 0 .00 - < 0.01 1.00E00 1.00E00 5-phosphoribose 1-diphosphate biosynthetic process (GO:0006015) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of corticotropin-releasing hormone secretion (GO:0051466) 2 0 .00 - < 0.01 1.00E00 1.00E00 D-ribose metabolic process (GO:0006014) 3 0 .00 - < 0.01 1.00E00 1.00E00 anterograde dendritic transport of messenger ribonucleoprotein complex (GO:0098964) 3 0 .00 - < 0.01 1.00E00 1.00E00 mannose metabolic process (GO:0006013) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cortisol secretion (GO:0051464) 4 0 .00 - < 0.01 1.00E00 1.00E00 dendritic transport of messenger ribonucleoprotein complex (GO:0098963) 2 0 .00 - < 0.01 1.00E00 1.00E00 galactose metabolic process (GO:0006012) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cortisol secretion (GO:0051463) 1 0 .00 - < 0.01 1.00E00 1.00E00 UDP-alpha-D-glucose metabolic process (GO:0006011) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cortisol secretion (GO:0051462) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of corticotropin secretion (GO:0051461) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of corticotropin secretion (GO:0051460) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent CUT catabolic process (GO:0071039) 2 0 .00 - < 0.01 1.00E00 1.00E00 TRAMP-dependent tRNA surveillance pathway (GO:0071038) 7 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent snRNA catabolic process (GO:0071037) 2 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent snoRNA catabolic process (GO:0071036) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic joint molecule formation (GO:0000709) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear polyadenylation-dependent rRNA catabolic process (GO:0071035) 7 0 .00 - < 0.01 1.00E00 1.00E00 meiotic strand invasion (GO:0000708) 1 0 .00 - < 0.01 1.00E00 1.00E00 CUT catabolic process (GO:0071034) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cytoplasmic microtubule (GO:1905755) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA recombinase assembly (GO:0000707) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break processing (GO:0000706) 3 0 .00 - < 0.01 1.00E00 1.00E00 nuclear mRNA surveillance of mRNA 3'-end processing (GO:0071031) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endosome to plasma membrane protein transport (GO:1905751) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of corticotropin secretion (GO:0051459) 6 0 .00 - < 0.01 1.00E00 1.00E00 retrograde axonal transport of mitochondrion (GO:0098958) 3 0 .00 - < 0.01 1.00E00 1.00E00 stress response to zinc ion (GO:1990359) 2 0 .00 - < 0.01 1.00E00 1.00E00 glucose catabolic process (GO:0006007) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cell fate specification (GO:0009996) 4 0 .00 - < 0.01 1.00E00 1.00E00 corticotropin secretion (GO:0051458) 2 0 .00 - < 0.01 1.00E00 1.00E00 anterograde axonal transport of mitochondrion (GO:0098957) 2 0 .00 - < 0.01 1.00E00 1.00E00 glucose metabolic process (GO:0006006) 118 0 .03 - < 0.01 1.00E00 1.00E00 maintenance of protein location in nucleus (GO:0051457) 25 0 .01 - < 0.01 1.00E00 1.00E00 oocyte differentiation (GO:0009994) 60 0 .02 - < 0.01 1.00E00 1.00E00 fucose metabolic process (GO:0006004) 17 1 .00 + > 100 4.95E-03 1.00E00 spindle attachment to meiosis I kinetochore (GO:0051455) 1 0 .00 - < 0.01 1.00E00 1.00E00 fructose 2,6-bisphosphate metabolic process (GO:0006003) 5 0 .00 - < 0.01 1.00E00 1.00E00 intracellular water homeostasis (GO:0009992) 6 0 .00 - < 0.01 1.00E00 1.00E00 intracellular pH elevation (GO:0051454) 7 0 .00 - < 0.01 1.00E00 1.00E00 receptor diffusion trapping (GO:0098953) 8 0 .00 - < 0.01 1.00E00 1.00E00 fructose 6-phosphate metabolic process (GO:0006002) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular pH (GO:0051453) 90 0 .03 - < 0.01 1.00E00 1.00E00 fructose catabolic process (GO:0006001) 3 0 .00 - < 0.01 1.00E00 1.00E00 intracellular pH reduction (GO:0051452) 54 0 .02 - < 0.01 1.00E00 1.00E00 fructose metabolic process (GO:0006000) 14 0 .00 - < 0.01 1.00E00 1.00E00 myoblast migration (GO:0051451) 13 0 .00 - < 0.01 1.00E00 1.00E00 myoblast proliferation (GO:0051450) 13 0 .00 - < 0.01 1.00E00 1.00E00 nuclear mRNA surveillance (GO:0071028) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endosome to plasma membrane protein transport (GO:1905749) 4 0 .00 - < 0.01 1.00E00 1.00E00 nuclear RNA surveillance (GO:0071027) 15 0 .00 - < 0.01 1.00E00 1.00E00 hard palate morphogenesis (GO:1905748) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasmic RNA surveillance (GO:0071026) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of saliva secretion (GO:1905747) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA surveillance (GO:0071025) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA cis splicing, via spliceosome (GO:1905746) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA cis splicing, via spliceosome (GO:1905744) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell recognition (GO:0009988) 69 0 .02 - < 0.01 1.00E00 1.00E00 cellular process (GO:0009987) 15523 6 4.53 + 1.33 3.47E-01 1.00E00 gap junction-mediated intercellular transport (GO:1990349) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated calcium channel activity (GO:1901387) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic cell cycle (GO:0051447) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of voltage-gated calcium channel activity (GO:1901386) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of meiotic cell cycle (GO:0051446) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of voltage-gated calcium channel activity (GO:1901385) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of meiotic cell cycle (GO:0051445) 68 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of chorionic trophoblast cell proliferation (GO:1901384) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin-protein transferase activity (GO:0051444) 12 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport, postsynaptic endosome to lysosome (GO:0098943) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chorionic trophoblast cell proliferation (GO:1901383) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin-protein transferase activity (GO:0051443) 19 0 .01 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by trans-synaptic protein complex (GO:0098942) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chorionic trophoblast cell proliferation (GO:1901382) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of potassium ion transmembrane transport (GO:1901381) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of potassium ion transmembrane transport (GO:1901380) 22 0 .01 - < 0.01 1.00E00 1.00E00 telomeric 3' overhang formation (GO:0031860) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of L-proline import across plasma membrane (GO:1905737) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of L-proline import across plasma membrane (GO:1905735) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of potassium ion transmembrane transport (GO:1901379) 76 0 .02 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin-protein transferase activity (GO:0051438) 33 0 .01 - < 0.01 1.00E00 1.00E00 anterograde dendritic transport (GO:0098937) 11 0 .00 - < 0.01 1.00E00 1.00E00 dendritic transport (GO:0098935) 14 0 .00 - < 0.01 1.00E00 1.00E00 acetate ester transport (GO:1901374) 5 0 .00 - < 0.01 1.00E00 1.00E00 cytidine deamination (GO:0009972) 6 0 .00 - < 0.01 1.00E00 1.00E00 lipid hydroperoxide transport (GO:1901373) 2 0 .00 - < 0.01 1.00E00 1.00E00 axonal transport (GO:0098930) 64 0 .02 - < 0.01 1.00E00 1.00E00 response to glutathione (GO:1901370) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to microtubule end (GO:1905725) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to magnetism (GO:0071000) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of signal transduction (GO:0009968) 1356 0 .40 - < 0.01 1.00E00 1.00E00 positive regulation of signal transduction (GO:0009967) 1584 0 .46 - < 0.01 1.00E00 1.00E00 presynaptic signal transduction (GO:0098928) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of signal transduction (GO:0009966) 3069 0 .89 - < 0.01 6.01E-01 1.00E00 vesicle-mediated transport between endosomal compartments (GO:0098927) 30 0 .01 - < 0.01 1.00E00 1.00E00 postsynaptic signal transduction (GO:0098926) 52 0 .02 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission (GO:0098925) 1 0 .00 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by nitric oxide (GO:0098924) 1 0 .00 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by soluble gas (GO:0098923) 1 0 .00 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by endocannabinoid (GO:0098921) 3 0 .00 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling by lipid (GO:0098920) 3 0 .00 - < 0.01 1.00E00 1.00E00 protection from non-homologous end joining at telomere (GO:0031848) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to perinuclear region of cytoplasm (GO:1905719) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cornification (GO:1905716) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cornification (GO:1905715) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to phosphatidylethanolamine (GO:1905711) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of membrane permeability (GO:1905710) 30 0 .01 - < 0.01 1.00E00 1.00E00 epidermal cell fate specification (GO:0009957) 5 0 .00 - < 0.01 1.00E00 1.00E00 radial pattern formation (GO:0009956) 1 0 .00 - < 0.01 1.00E00 1.00E00 microtubule nucleation by microtubule organizing center (GO:0051418) 5 0 .00 - < 0.01 1.00E00 1.00E00 retrograde trans-synaptic signaling (GO:0098917) 7 0 .00 - < 0.01 1.00E00 1.00E00 anterograde trans-synaptic signaling (GO:0098916) 417 0 .12 - < 0.01 1.00E00 1.00E00 proximal/distal pattern formation (GO:0009954) 34 0 .01 - < 0.01 1.00E00 1.00E00 membrane repolarization during ventricular cardiac muscle cell action potential (GO:0098915) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to rapamycin (GO:1901355) 6 0 .00 - < 0.01 1.00E00 1.00E00 dorsal/ventral pattern formation (GO:0009953) 86 0 .03 - < 0.01 1.00E00 1.00E00 microtubule nucleation by interphase microtubule organizing center (GO:0051415) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane repolarization during atrial cardiac muscle cell action potential (GO:0098914) 5 0 .00 - < 0.01 1.00E00 1.00E00 anterior/posterior pattern specification (GO:0009952) 213 0 .06 - < 0.01 1.00E00 1.00E00 response to cortisol (GO:0051414) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to insulin-like growth factor stimulus (GO:1990314) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to cortisone (GO:0051413) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane depolarization during atrial cardiac muscle cell action potential (GO:0098912) 3 0 .00 - < 0.01 1.00E00 1.00E00 dorsal/ventral axis specification (GO:0009950) 14 0 .00 - < 0.01 1.00E00 1.00E00 response to corticosterone (GO:0051412) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ventricular cardiac muscle cell action potential (GO:0098911) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of atrial cardiac muscle cell action potential (GO:0098910) 4 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of nitrogen compound (GO:0051410) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of release of cytochrome c from mitochondria (GO:0090199) 41 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of membrane permeability (GO:1905709) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glomerulus development (GO:0090194) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glomerulus development (GO:0090193) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial ATP synthesis coupled proton transport (GO:1905707) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glomerulus development (GO:0090192) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial ATP synthesis coupled proton transport (GO:1905706) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of branching involved in ureteric bud morphogenesis (GO:0090191) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of branching involved in ureteric bud morphogenesis (GO:0090190) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of inhibitory synapse assembly (GO:1905704) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inhibitory synapse assembly (GO:1905703) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inhibitory synapse assembly (GO:1905702) 5 0 .00 - < 0.01 1.00E00 1.00E00 polarity specification of anterior/posterior axis (GO:0009949) 1 0 .00 - < 0.01 1.00E00 1.00E00 anterior/posterior axis specification (GO:0009948) 59 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell action potential involved in regulation of contraction (GO:0098909) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to nitrosative stress (GO:0051409) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuronal action potential (GO:0098908) 5 0 .00 - < 0.01 1.00E00 1.00E00 proximal/distal axis specification (GO:0009946) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of SA node cell action potential (GO:0098907) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Purkinje myocyte action potential (GO:0098906) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vasculature development involved in avascular cornea development in camera-type eye (GO:1901346) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bundle of His cell action potential (GO:0098905) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of AV node cell action potential (GO:0098904) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to leptomycin B (GO:1901344) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during action potential (GO:0098903) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vasculature development (GO:1901343) 111 0 .03 - < 0.01 1.00E00 1.00E00 stress-activated MAPK cascade (GO:0051403) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of membrane depolarization during action potential (GO:0098902) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vasculature development (GO:1901342) 302 0 .09 - < 0.01 1.00E00 1.00E00 neuron apoptotic process (GO:0051402) 116 0 .03 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell action potential (GO:0098901) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of store-operated calcium channel activity (GO:1901341) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of action potential (GO:0098900) 61 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of store-operated calcium channel activity (GO:1901340) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching involved in ureteric bud morphogenesis (GO:0090189) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of pancreatic juice secretion (GO:0090188) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pancreatic juice secretion (GO:0090187) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pancreatic juice secretion (GO:0090186) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of kidney development (GO:0090185) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of kidney development (GO:0090184) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of kidney development (GO:0090183) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of secretion of lysosomal enzymes (GO:0090182) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholesterol metabolic process (GO:0090181) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of store-operated calcium channel activity (GO:1901339) 7 0 .00 - < 0.01 1.00E00 1.00E00 thioester transport (GO:1901337) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactone catabolic process (GO:1901335) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactone metabolic process (GO:1901334) 14 0 .00 - < 0.01 1.00E00 1.00E00 cell tip growth (GO:0009932) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of odontoblast differentiation (GO:1901331) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of odontoblast differentiation (GO:1901330) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of planar polarity involved in neural tube closure (GO:0090177) 1 0 .00 - < 0.01 1.00E00 1.00E00 microtubule cytoskeleton organization involved in establishment of planar polarity (GO:0090176) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of planar polarity (GO:0090175) 6 0 .00 - < 0.01 1.00E00 1.00E00 organelle membrane fusion (GO:0090174) 103 0 .03 - < 0.01 1.00E00 1.00E00 chondrocyte morphogenesis (GO:0090171) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Golgi inheritance (GO:0090170) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of odontoblast differentiation (GO:1901329) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to cytochalasin B (GO:1901328) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to tacrolimus (GO:1901327) 2 0 .00 - < 0.01 1.00E00 1.00E00 dendrite self-avoidance (GO:0070593) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spindle assembly (GO:0090169) 34 0 .01 - < 0.01 1.00E00 1.00E00 Golgi reassembly (GO:0090168) 5 0 .00 - < 0.01 1.00E00 1.00E00 Golgi disassembly (GO:0090166) 6 0 .00 - < 0.01 1.00E00 1.00E00 asymmetric Golgi ribbon formation (GO:0090164) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of epithelial cell polarity (GO:0090162) 31 0 .01 - < 0.01 1.00E00 1.00E00 Golgi ribbon formation (GO:0090161) 11 0 .00 - < 0.01 1.00E00 1.00E00 Golgi to lysosome transport (GO:0090160) 11 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion transmembrane transport (GO:0070588) 219 0 .06 - < 0.01 1.00E00 1.00E00 regulation of cell-cell adhesion involved in gastrulation (GO:0070587) 10 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell adhesion involved in gastrulation (GO:0070586) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to mitochondrion (GO:0070585) 90 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of flagellated sperm motility (GO:1901318) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of flagellated sperm motility (GO:1901317) 24 0 .01 - < 0.01 1.00E00 1.00E00 hormone transport (GO:0009914) 105 0 .03 - < 0.01 1.00E00 1.00E00 epidermal cell differentiation (GO:0009913) 208 0 .06 - < 0.01 1.00E00 1.00E00 auditory receptor cell fate commitment (GO:0009912) 4 0 .00 - < 0.01 1.00E00 1.00E00 generation of neurons (GO:0048699) 1205 0 .35 - < 0.01 1.00E00 1.00E00 negative regulation of collateral sprouting in absence of injury (GO:0048698) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of collateral sprouting in absence of injury (GO:0048697) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collateral sprouting in absence of injury (GO:0048696) 3 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum membrane organization (GO:0090158) 13 0 .00 - < 0.01 1.00E00 1.00E00 intracellular sphingolipid homeostasis (GO:0090156) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sphingolipid biosynthetic process (GO:0090155) 6 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II (GO:0001193) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of axon extension involved in regeneration (GO:0048692) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sphingolipid biosynthetic process (GO:0090154) 7 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of transcriptional fidelity during transcription elongation (GO:0001192) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sphingolipid biosynthetic process (GO:0090153) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of axon extension involved in regeneration (GO:0048690) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to mitochondrial membrane involved in mitochondrial fission (GO:0090152) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to mitochondrial membrane (GO:0090151) 34 0 .01 - < 0.01 1.00E00 1.00E00 establishment of protein localization to membrane (GO:0090150) 224 0 .07 - < 0.01 1.00E00 1.00E00 cadmium ion transmembrane transport (GO:0070574) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of spermidine biosynthetic process (GO:1901307) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuron projection regeneration (GO:0070572) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron projection regeneration (GO:0070571) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spermidine biosynthetic process (GO:1901304) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron projection regeneration (GO:0070570) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cargo loading into COPII-coated vesicle (GO:1901303) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitric-oxide synthase activity (GO:0050999) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cargo loading into COPII-coated vesicle (GO:1901301) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide-mediated programmed cell death (GO:1901300) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid catabolic process (GO:0050996) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipid catabolic process (GO:0050995) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lipid catabolic process (GO:0050994) 64 0 .02 - < 0.01 1.00E00 1.00E00 dimethylallyl diphosphate metabolic process (GO:0050993) 2 0 .00 - < 0.01 1.00E00 1.00E00 dimethylallyl diphosphate biosynthetic process (GO:0050992) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sprouting of injured axon (GO:0048688) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase I preinitiation complex assembly (GO:0001188) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sprouting of injured axon (GO:0048687) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial membrane fission (GO:0090149) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sprouting of injured axon (GO:0048686) 3 0 .00 - < 0.01 1.00E00 1.00E00 membrane fission (GO:0090148) 45 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of collateral sprouting of intact axon in response to injury (GO:0048685) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collateral sprouting of intact axon in response to injury (GO:0048683) 1 0 .00 - < 0.01 1.00E00 1.00E00 sprouting of injured axon (GO:0048682) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial nucleoid organization (GO:0090144) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of axon regeneration (GO:0048681) 15 0 .00 - < 0.01 1.00E00 1.00E00 nucleoid organization (GO:0090143) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of axon regeneration (GO:0048680) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial fission (GO:0090141) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial fission (GO:0090140) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D receptor signaling pathway (GO:0070564) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vitamin D receptor signaling pathway (GO:0070563) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vitamin D receptor signaling pathway (GO:0070562) 10 0 .00 - < 0.01 1.00E00 1.00E00 vitamin D receptor signaling pathway (GO:0070561) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein secretion by platelet (GO:0070560) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of axon regeneration (GO:0048679) 29 0 .01 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus (GO:0050982) 58 0 .02 - < 0.01 1.00E00 1.00E00 response to axon injury (GO:0048678) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of transcriptional start site selection at RNA polymerase II promoter (GO:0001178) 1 0 .00 - < 0.01 1.00E00 1.00E00 axon extension involved in regeneration (GO:0048677) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin cytoskeleton organization by cell-cell adhesion (GO:0090138) 1 0 .00 - < 0.01 1.00E00 1.00E00 axon extension (GO:0048675) 46 0 .01 - < 0.01 1.00E00 1.00E00 epithelial cell-cell adhesion (GO:0090136) 17 0 .00 - < 0.01 1.00E00 1.00E00 transcriptional start site selection at RNA polymerase II promoter (GO:0001174) 1 0 .00 - < 0.01 1.00E00 1.00E00 actin filament branching (GO:0090135) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA-templated transcriptional start site selection (GO:0001173) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of collateral sprouting (GO:0048672) 10 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in mesendoderm migration (GO:0090134) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA-templated transcription (GO:0001172) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of collateral sprouting (GO:0048671) 12 0 .00 - < 0.01 1.00E00 1.00E00 mesendoderm migration (GO:0090133) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collateral sprouting (GO:0048670) 21 0 .01 - < 0.01 1.00E00 1.00E00 epithelium migration (GO:0090132) 36 0 .01 - < 0.01 1.00E00 1.00E00 mesenchyme migration (GO:0090131) 5 0 .00 - < 0.01 1.00E00 1.00E00 tissue migration (GO:0090130) 42 0 .01 - < 0.01 1.00E00 1.00E00 response to interleukin-1 (GO:0070555) 100 0 .03 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception of touch (GO:0050976) 4 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of touch (GO:0050975) 6 0 .00 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception (GO:0050974) 39 0 .01 - < 0.01 1.00E00 1.00E00 collateral sprouting in absence of injury (GO:0048669) 3 0 .00 - < 0.01 1.00E00 1.00E00 collateral sprouting (GO:0048668) 16 0 .00 - < 0.01 1.00E00 1.00E00 cell morphogenesis involved in neuron differentiation (GO:0048667) 450 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of synapse maturation (GO:0090129) 8 0 .00 - < 0.01 1.00E00 1.00E00 neuron development (GO:0048666) 893 0 .26 - < 0.01 1.00E00 1.00E00 regulation of synapse maturation (GO:0090128) 26 0 .01 - < 0.01 1.00E00 1.00E00 neuron fate specification (GO:0048665) 34 0 .01 - < 0.01 1.00E00 1.00E00 neuron fate determination (GO:0048664) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein-containing complex assembly involved in synapse maturation (GO:0090126) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuron fate commitment (GO:0048663) 70 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell proliferation (GO:0048662) 49 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell proliferation (GO:0048661) 85 0 .02 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell proliferation (GO:0048660) 138 0 .04 - < 0.01 1.00E00 1.00E00 cholesterol ester hydrolysis involved in cholesterol transport (GO:0090122) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to linoleic acid (GO:0070543) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to fatty acid (GO:0070542) 60 0 .02 - < 0.01 1.00E00 1.00E00 response to platinum ion (GO:0070541) 3 0 .00 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of pain (GO:0050968) 3 0 .00 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception of pain (GO:0050966) 15 0 .00 - < 0.01 1.00E00 1.00E00 detection of temperature stimulus involved in sensory perception of pain (GO:0050965) 22 0 .01 - < 0.01 1.00E00 1.00E00 detection of calcium ion (GO:0005513) 14 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle cell proliferation (GO:0048659) 8 0 .00 - < 0.01 1.00E00 1.00E00 detection of light stimulus involved in sensory perception (GO:0050962) 23 0 .01 - < 0.01 1.00E00 1.00E00 detection of temperature stimulus involved in sensory perception (GO:0050961) 26 0 .01 - < 0.01 1.00E00 1.00E00 detection of temperature stimulus involved in thermoception (GO:0050960) 5 0 .00 - < 0.01 1.00E00 1.00E00 vesicle-mediated cholesterol transport (GO:0090119) 9 0 .00 - < 0.01 1.00E00 1.00E00 receptor-mediated endocytosis involved in cholesterol transport (GO:0090118) 2 0 .00 - < 0.01 1.00E00 1.00E00 endosome to lysosome transport of low-density lipoprotein particle (GO:0090117) 2 0 .00 - < 0.01 1.00E00 1.00E00 COPII-coated vesicle budding (GO:0090114) 40 0 .01 - < 0.01 1.00E00 1.00E00 COPII-coated vesicle cargo loading (GO:0090110) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein K63-linked deubiquitination (GO:0070536) 26 0 .01 - < 0.01 1.00E00 1.00E00 protein K63-linked ubiquitination (GO:0070534) 58 0 .02 - < 0.01 1.00E00 1.00E00 equilibrioception (GO:0050957) 8 0 .00 - < 0.01 1.00E00 1.00E00 thermoception (GO:0050955) 8 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of mechanical stimulus (GO:0050954) 194 0 .06 - < 0.01 1.00E00 1.00E00 sensory perception of light stimulus (GO:0050953) 226 0 .07 - < 0.01 1.00E00 1.00E00 sensory perception of temperature stimulus (GO:0050951) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell-substrate junction assembly (GO:0090109) 63 0 .02 - < 0.01 1.00E00 1.00E00 anatomical structure formation involved in morphogenesis (GO:0048646) 988 1 .29 + 3.47 2.56E-01 1.00E00 positive regulation of high-density lipoprotein particle assembly (GO:0090108) 2 0 .00 - < 0.01 1.00E00 1.00E00 animal organ formation (GO:0048645) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of high-density lipoprotein particle assembly (GO:0090107) 3 0 .00 - < 0.01 1.00E00 1.00E00 muscle organ morphogenesis (GO:0048644) 78 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle tissue development (GO:0048643) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle tissue development (GO:0048642) 4 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic epsilon cell differentiation (GO:0090104) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle tissue development (GO:0048641) 26 0 .01 - < 0.01 1.00E00 1.00E00 cochlea morphogenesis (GO:0090103) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of developmental growth (GO:0048640) 96 0 .03 - < 0.01 1.00E00 1.00E00 cochlea development (GO:0090102) 53 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090101) 154 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090100) 106 0 .03 - < 0.01 1.00E00 1.00E00 protein kinase C signaling (GO:0070528) 3 0 .00 - < 0.01 1.00E00 1.00E00 small molecule biosynthetic process (GO:0044283) 465 2 .14 + 14.75 7.19E-03 1.00E00 platelet aggregation (GO:0070527) 48 0 .01 - < 0.01 1.00E00 1.00E00 small molecule catabolic process (GO:0044282) 350 1 .10 + 9.80 9.78E-02 1.00E00 tRNA threonylcarbamoyladenosine metabolic process (GO:0070525) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of developmental growth (GO:0048639) 161 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of pigment cell differentiation (GO:0050942) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of developmental growth (GO:0048638) 312 0 .09 - < 0.01 1.00E00 1.00E00 positive regulation of muscle organ development (GO:0048636) 24 0 .01 - < 0.01 1.00E00 1.00E00 glial cell projection elongation (GO:0106091) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of muscle organ development (GO:0048635) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle organ development (GO:0048634) 47 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle tissue growth (GO:0048633) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle tissue growth (GO:0048632) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle tissue growth (GO:0048631) 8 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle tissue growth (GO:0048630) 7 0 .00 - < 0.01 1.00E00 1.00E00 sulfur compound catabolic process (GO:0044273) 47 0 .01 - < 0.01 1.00E00 1.00E00 sulfur compound biosynthetic process (GO:0044272) 155 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of cell adhesion involved in sprouting angiogenesis (GO:0106089) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion involved in sprouting angiogenesis (GO:0106088) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pigment cell differentiation (GO:0050932) 8 0 .00 - < 0.01 1.00E00 1.00E00 pigment cell differentiation (GO:0050931) 32 0 .01 - < 0.01 1.00E00 1.00E00 myoblast development (GO:0048627) 4 0 .00 - < 0.01 1.00E00 1.00E00 induction of positive chemotaxis (GO:0050930) 15 0 .00 - < 0.01 1.00E00 1.00E00 myoblast fate specification (GO:0048626) 1 0 .00 - < 0.01 1.00E00 1.00E00 myoblast fate commitment (GO:0048625) 6 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic digestive tract morphogenesis (GO:0048621) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycerol ether catabolic process (GO:0044269) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein-DNA complex remodeling (GO:0001120) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion import (GO:0070509) 41 0 .01 - < 0.01 1.00E00 1.00E00 cholesterol import (GO:0070508) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule cytoskeleton organization (GO:0070507) 167 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated DNA replication initiation (GO:0032298) 2 0 .00 - < 0.01 1.00E00 1.00E00 induction of negative chemotaxis (GO:0050929) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of positive chemotaxis (GO:0050928) 1 0 .00 - < 0.01 1.00E00 1.00E00 peripheral nervous system axon ensheathment (GO:0032292) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of positive chemotaxis (GO:0050927) 26 0 .01 - < 0.01 1.00E00 1.00E00 axon ensheathment in central nervous system (GO:0032291) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of positive chemotaxis (GO:0050926) 27 0 .01 - < 0.01 1.00E00 1.00E00 peripheral nervous system myelin formation (GO:0032290) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of negative chemotaxis (GO:0050925) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of negative chemotaxis (GO:0050924) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial RNA modification (GO:1900864) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of negative chemotaxis (GO:0050923) 4 0 .00 - < 0.01 1.00E00 1.00E00 embryonic hindgut morphogenesis (GO:0048619) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemotaxis (GO:0050922) 44 1 .01 + 77.95 1.28E-02 1.00E00 aminoacyl-tRNA metabolism involved in translational fidelity (GO:0106074) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemotaxis (GO:0050921) 147 0 .04 - < 0.01 1.00E00 1.00E00 embryonic foregut morphogenesis (GO:0048617) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemotaxis (GO:0050920) 209 1 .06 + 16.41 5.94E-02 1.00E00 negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106072) 15 0 .00 - < 0.01 1.00E00 1.00E00 protein-DNA-RNA complex disassembly (GO:0001117) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106071) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway (GO:0106070) 21 0 .01 - < 0.01 1.00E00 1.00E00 protein-DNA-RNA complex organization (GO:0001115) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic ectodermal digestive tract morphogenesis (GO:0048613) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA-templated transcription open complex formation (GO:0001112) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic ectodermal digestive tract development (GO:0048611) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase II promoter clearance (GO:0001111) 3 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system myelin formation (GO:0032289) 8 0 .00 - < 0.01 1.00E00 1.00E00 myelin assembly (GO:0032288) 25 0 .01 - < 0.01 1.00E00 1.00E00 peripheral nervous system myelin maintenance (GO:0032287) 9 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system myelin maintenance (GO:0032286) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative chemotaxis (GO:0050919) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive chemotaxis (GO:0050918) 52 0 .02 - < 0.01 1.00E00 1.00E00 sensory perception of umami taste (GO:0050917) 7 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of sweet taste (GO:0050916) 7 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of sour taste (GO:0050915) 9 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of salty taste (GO:0050914) 4 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of bitter taste (GO:0050913) 44 0 .01 - < 0.01 1.00E00 1.00E00 multicellular organismal reproductive process (GO:0048609) 989 0 .29 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception of taste (GO:0050912) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cobalamin metabolic process (GO:0106064) 1 0 .00 - < 0.01 1.00E00 1.00E00 promoter clearance during DNA-templated transcription (GO:0001109) 3 0 .00 - < 0.01 1.00E00 1.00E00 reproductive structure development (GO:0048608) 305 1 .09 + 11.25 8.57E-02 1.00E00 detection of chemical stimulus involved in sensory perception of smell (GO:0050911) 440 0 .13 - < 0.01 1.00E00 1.00E00 detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to acid chemical (GO:0001101) 138 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of exit from mitosis (GO:0001100) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular catabolic process (GO:0044248) 297 0 .09 - < 0.01 1.00E00 1.00E00 polysaccharide digestion (GO:0044245) 4 0 .00 - < 0.01 1.00E00 1.00E00 lipid digestion (GO:0044241) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gonadotropin secretion (GO:0032278) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gonadotropin secretion (GO:0032277) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gonadotropin secretion (GO:0032276) 12 0 .00 - < 0.01 1.00E00 1.00E00 luteinizing hormone secretion (GO:0032275) 4 0 .00 - < 0.01 1.00E00 1.00E00 gonadotropin secretion (GO:0032274) 6 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of taste (GO:0050909) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein polymerization (GO:0032273) 92 0 .03 - < 0.01 1.00E00 1.00E00 detection of light stimulus involved in visual perception (GO:0050908) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein polymerization (GO:0032272) 68 0 .02 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus involved in sensory perception (GO:0050907) 487 0 .14 - < 0.01 1.00E00 1.00E00 regulation of protein polymerization (GO:0032271) 200 0 .06 - < 0.01 1.00E00 1.00E00 detection of stimulus involved in sensory perception (GO:0050906) 564 0 .16 - < 0.01 1.00E00 1.00E00 positive regulation of calcineurin-mediated signaling (GO:0106058) 21 0 .01 - < 0.01 1.00E00 1.00E00 neuromuscular process (GO:0050905) 161 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of calcineurin-mediated signaling (GO:0106057) 15 0 .00 - < 0.01 1.00E00 1.00E00 diapedesis (GO:0050904) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcineurin-mediated signaling (GO:0106056) 40 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte adhesive activation (GO:0050902) 2 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte tethering or rolling (GO:0050901) 20 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte migration (GO:0050900) 241 0 .07 - < 0.01 1.00E00 1.00E00 lipid ubiquitination (GO:0120323) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipid modification by small protein conjugation (GO:0120322) 1 0 .00 - < 0.01 1.00E00 1.00E00 IMP salvage (GO:0032264) 5 0 .00 - < 0.01 1.00E00 1.00E00 GMP salvage (GO:0032263) 5 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleotide salvage (GO:0032262) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to osmotic stress (GO:0106049) 13 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleotide salvage (GO:0032261) 21 0 .01 - < 0.01 1.00E00 1.00E00 spermidine deacetylation (GO:0106048) 1 0 .00 - < 0.01 1.00E00 1.00E00 polyamine deacetylation (GO:0106047) 1 0 .00 - < 0.01 1.00E00 1.00E00 guanine deglycation, glyoxal removal (GO:0106046) 1 0 .00 - < 0.01 1.00E00 1.00E00 guanine deglycation, methylglyoxal removal (GO:0106045) 1 0 .00 - < 0.01 1.00E00 1.00E00 guanine deglycation (GO:0106044) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of GABA-A receptor activity (GO:0106040) 1 0 .00 - < 0.01 1.00E00 1.00E00 sperm mitochondrial sheath assembly (GO:0120317) 6 0 .00 - < 0.01 1.00E00 1.00E00 sperm flagellum assembly (GO:0120316) 57 0 .02 - < 0.01 1.00E00 1.00E00 methylation (GO:0032259) 225 0 .07 - < 0.01 1.00E00 1.00E00 dense core granule localization (GO:0032253) 18 0 .01 - < 0.01 1.00E00 1.00E00 secretory granule localization (GO:0032252) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of membrane depolarization during cardiac muscle cell action potential (GO:1900827) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane depolarization during cardiac muscle cell action potential (GO:1900826) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane depolarization during cardiac muscle cell action potential (GO:1900825) 4 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection fasciculation (GO:0106030) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of pigmentation (GO:0120305) 17 0 .00 - < 0.01 1.00E00 1.00E00 background adaptation (GO:0120302) 2 0 .00 - < 0.01 1.00E00 1.00E00 CTP salvage (GO:0044211) 3 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' CTP biosynthetic process (GO:0044210) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleoside transport (GO:0032244) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleoside transport (GO:0032243) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleoside transport (GO:0032242) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleobase-containing compound transport (GO:0032241) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection retraction (GO:0106028) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleobase-containing compound transport (GO:0032240) 4 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection organization (GO:0106027) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of vesicle docking (GO:0106022) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vesicle docking (GO:0106020) 2 0 .00 - < 0.01 1.00E00 1.00E00 AMP salvage (GO:0044209) 5 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' AMP biosynthetic process (GO:0044208) 8 0 .00 - < 0.01 1.00E00 1.00E00 UMP salvage (GO:0044206) 6 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' UMP biosynthetic process (GO:0044205) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleobase-containing compound transport (GO:0032239) 18 0 .01 - < 0.01 1.00E00 1.00E00 adenosine transport (GO:0032238) 5 0 .00 - < 0.01 1.00E00 1.00E00 activation of store-operated calcium channel activity (GO:0032237) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament bundle assembly (GO:0032233) 61 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of actin filament bundle assembly (GO:0032232) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of actin filament bundle assembly (GO:0032231) 103 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, GABAergic (GO:0032230) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inflammatory response to wounding (GO:0106016) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inflammatory response to wounding (GO:0106015) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inflammatory response to wounding (GO:0106014) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission, GABAergic (GO:0032229) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, GABAergic (GO:0032228) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission, dopaminergic (GO:0032227) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, dopaminergic (GO:0032226) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, dopaminergic (GO:0032225) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission, cholinergic (GO:0032224) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission, cholinergic (GO:0032223) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic transmission, cholinergic (GO:0032222) 8 0 .00 - < 0.01 1.00E00 1.00E00 RNA 5'-cap (guanine-N7)-methylation (GO:0106005) 3 0 .00 - < 0.01 1.00E00 1.00E00 tRNA (guanine-N7)-methylation (GO:0106004) 2 0 .00 - < 0.01 1.00E00 1.00E00 intestinal hexose absorption (GO:0106001) 5 0 .00 - < 0.01 1.00E00 1.00E00 riboflavin transport (GO:0032218) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance via semi-conservative replication (GO:0032214) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance via semi-conservative replication (GO:0032213) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance via telomerase (GO:0032212) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance via telomerase (GO:0032211) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance via telomerase (GO:0032210) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance via recombination (GO:0032208) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance via recombination (GO:0032207) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance (GO:0032206) 74 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance (GO:0032205) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance (GO:0032204) 111 0 .03 - < 0.01 1.00E00 1.00E00 telomere formation via telomerase (GO:0032203) 1 0 .00 - < 0.01 1.00E00 1.00E00 telomere assembly (GO:0032202) 4 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance via semi-conservative replication (GO:0032201) 7 0 .00 - < 0.01 1.00E00 1.00E00 telomere organization (GO:0032200) 103 0 .03 - < 0.01 1.00E00 1.00E00 symbiont-mediated disruption of host cell PML body (GO:0075342) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidic acid biosynthetic process (GO:1905695) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidic acid biosynthetic process (GO:1905694) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidic acid biosynthetic process (GO:1905693) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipid droplet disassembly (GO:1905691) 7 0 .00 - < 0.01 1.00E00 1.00E00 renal amino acid absorption (GO:1990297) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nerve growth factor receptor activity (GO:0051394) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA acetylation (GO:0051391) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of plasma membrane repair (GO:1905686) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane repair (GO:1905684) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurotrophin TRK receptor signaling pathway (GO:0051388) 5 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0098887) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neurotrophin TRK receptor signaling pathway (GO:0051387) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotrophin TRK receptor signaling pathway (GO:0051386) 11 0 .00 - < 0.01 1.00E00 1.00E00 modification of postsynaptic actin cytoskeleton (GO:0098885) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to mineralocorticoid (GO:0051385) 37 0 .01 - < 0.01 1.00E00 1.00E00 postsynaptic neurotransmitter receptor internalization (GO:0098884) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to glucocorticoid (GO:0051384) 138 0 .04 - < 0.01 1.00E00 1.00E00 synapse pruning (GO:0098883) 10 0 .00 - < 0.01 1.00E00 1.00E00 kinetochore organization (GO:0051383) 18 0 .01 - < 0.01 1.00E00 1.00E00 kinetochore assembly (GO:0051382) 14 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of postsynaptic specialization structure (GO:0098880) 11 0 .00 - < 0.01 1.00E00 1.00E00 RNA localization to chromatin (GO:1990280) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adaptive immune memory response (GO:1905676) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adaptive immune memory response (GO:1905675) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adaptive immune memory response (GO:1905674) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lysosome organization (GO:1905673) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lysosome organization (GO:1905672) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lysosome organization (GO:1905671) 13 0 .00 - < 0.01 1.00E00 1.00E00 TORC2 complex disassembly (GO:1905670) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter receptor transport to plasma membrane (GO:0098877) 12 0 .00 - < 0.01 1.00E00 1.00E00 vesicle-mediated transport to the plasma membrane (GO:0098876) 133 0 .04 - < 0.01 1.00E00 1.00E00 action potential propagation (GO:0098870) 11 0 .00 - < 0.01 1.00E00 1.00E00 TORC1 complex assembly (GO:1905669) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to endosome (GO:1905668) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to endosome (GO:1905667) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to endosome (GO:1905666) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion import across plasma membrane (GO:1905665) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion import across plasma membrane (GO:1905664) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular oxidant detoxification (GO:0098869) 91 0 .03 - < 0.01 1.00E00 1.00E00 bone growth (GO:0098868) 31 0 .01 - < 0.01 1.00E00 1.00E00 response to gold nanoparticle (GO:1990268) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to transition metal nanoparticle (GO:1990267) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to potassium ion starvation (GO:0051365) 2 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil migration (GO:1990266) 66 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity (GO:1990264) 3 0 .00 - < 0.01 1.00E00 1.00E00 anti-Mullerian hormone receptor signaling pathway (GO:1990262) 2 0 .00 - < 0.01 1.00E00 1.00E00 pre-mRNA catabolic process (GO:1990261) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of artery morphogenesis (GO:1905653) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of artery morphogenesis (GO:1905651) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide-mediated programmed cell death (GO:1901299) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of catabolic process (GO:0009896) 529 0 .15 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide-mediated programmed cell death (GO:1901298) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of catabolic process (GO:0009895) 363 0 .11 - < 0.01 1.00E00 1.00E00 intestinal lipid absorption (GO:0098856) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of catabolic process (GO:0009894) 1029 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of metabolic process (GO:0009893) 3472 0 1.01 - < 0.01 5.98E-01 1.00E00 proprioception involved in equilibrioception (GO:0051355) 1 0 .00 - < 0.01 1.00E00 1.00E00 signal clustering (GO:1990256) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metabolic process (GO:0009892) 2723 0 .79 - < 0.01 1.00E00 1.00E00 negative regulation of oxidoreductase activity (GO:0051354) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of biosynthetic process (GO:0009891) 2653 0 .77 - < 0.01 1.00E00 1.00E00 positive regulation of oxidoreductase activity (GO:0051353) 32 0 .01 - < 0.01 1.00E00 1.00E00 nucleoside phosphate biosynthetic process (GO:1901293) 296 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of biosynthetic process (GO:0009890) 2171 0 .63 - < 0.01 1.00E00 1.00E00 nucleoside phosphate catabolic process (GO:1901292) 134 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to leucine starvation (GO:1990253) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ligase activity (GO:0051351) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of double-strand break repair via single-strand annealing (GO:1901291) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lyase activity (GO:0051350) 15 0 .00 - < 0.01 1.00E00 1.00E00 succinyl-CoA biosynthetic process (GO:1901290) 1 0 .00 - < 0.01 1.00E00 1.00E00 proline import across plasma membrane (GO:1905647) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of biosynthetic process (GO:0009889) 5260 0 1.53 - < 0.01 3.48E-01 1.00E00 tissue development (GO:0009888) 1770 1 .52 + 1.94 4.17E-01 1.00E00 cellular detoxification of cadmium ion (GO:0098849) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to acetaldehyde (GO:1905641) 1 0 .00 - < 0.01 1.00E00 1.00E00 animal organ morphogenesis (GO:0009887) 976 0 .28 - < 0.01 1.00E00 1.00E00 positive regulation of lyase activity (GO:0051349) 27 0 .01 - < 0.01 1.00E00 1.00E00 succinyl-CoA catabolic process (GO:1901289) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to acetaldehyde (GO:1905640) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic animal morphogenesis (GO:0009886) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transferase activity (GO:0051348) 140 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of transferase activity (GO:0051347) 233 0 .07 - < 0.01 1.00E00 1.00E00 negative regulation of hydrolase activity (GO:0051346) 70 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of hydrolase activity (GO:0051345) 168 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of cyclic-nucleotide phosphodiesterase activity (GO:0051344) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic pattern specification (GO:0009880) 78 0 .02 - < 0.01 1.00E00 1.00E00 regulation of oxidoreductase activity (GO:0051341) 53 0 .02 - < 0.01 1.00E00 1.00E00 protein transport along microtubule (GO:0098840) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding (GO:1905636) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to chromatin (GO:1905634) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glyceraldehyde (GO:1905631) 1 0 .00 - < 0.01 1.00E00 1.00E00 folate transmembrane transport (GO:0098838) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to glyceraldehyde (GO:1905630) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transferase activity (GO:0051338) 411 0 .12 - < 0.01 1.00E00 1.00E00 regulation of hydrolase activity (GO:0051336) 283 0 .08 - < 0.01 1.00E00 1.00E00 regulation of serotonin biosynthetic process (GO:1905627) 1 0 .00 - < 0.01 1.00E00 1.00E00 intestinal folate absorption (GO:0098829) 1 0 .00 - < 0.01 1.00E00 1.00E00 modulation of inhibitory postsynaptic potential (GO:0098828) 7 0 .00 - < 0.01 1.00E00 1.00E00 paranodal junction maintenance (GO:1990227) 2 0 .00 - < 0.01 1.00E00 1.00E00 carbohydrate derivative transport (GO:1901264) 87 0 .03 - < 0.01 1.00E00 1.00E00 meiotic cell cycle (GO:0051321) 258 0 .08 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA cap binding (GO:1905612) 1 0 .00 - < 0.01 1.00E00 1.00E00 evoked excitatory postsynaptic potential (GO:0098817) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage colony-stimulating factor production (GO:1901258) 4 0 .00 - < 0.01 1.00E00 1.00E00 determination of bilateral symmetry (GO:0009855) 140 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage colony-stimulating factor production (GO:1901257) 1 0 .00 - < 0.01 1.00E00 1.00E00 attachment of meiotic spindle microtubules to kinetochore (GO:0051316) 1 0 .00 - < 0.01 1.00E00 1.00E00 modulation of excitatory postsynaptic potential (GO:0098815) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macrophage colony-stimulating factor production (GO:1901256) 6 0 .00 - < 0.01 1.00E00 1.00E00 attachment of mitotic spindle microtubules to kinetochore (GO:0051315) 17 0 .00 - < 0.01 1.00E00 1.00E00 spontaneous synaptic transmission (GO:0098814) 8 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-excision repair involved in interstrand cross-link repair (GO:1901255) 2 0 .00 - < 0.01 1.00E00 1.00E00 nuclear chromosome segregation (GO:0098813) 235 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular transport of viral material (GO:1901254) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intracellular transport of viral material (GO:1901253) 2 0 .00 - < 0.01 1.00E00 1.00E00 auxin metabolic process (GO:0009850) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular transport of viral material (GO:1901252) 3 0 .00 - < 0.01 1.00E00 1.00E00 meiotic metaphase chromosome alignment (GO:0051311) 5 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter reuptake (GO:0098810) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lung goblet cell differentiation (GO:1901251) 1 0 .00 - < 0.01 1.00E00 1.00E00 metaphase chromosome alignment (GO:0051310) 84 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric cap mesenchymal cell proliferation (GO:0090096) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metanephric cap mesenchymal cell proliferation (GO:0090095) 1 0 .00 - < 0.01 1.00E00 1.00E00 metanephric cap mesenchymal cell proliferation involved in metanephros development (GO:0090094) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell-matrix adhesion (GO:1905609) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of presynapse assembly (GO:1905608) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway (GO:0090092) 274 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of presynapse assembly (GO:1905607) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular matrix disassembly (GO:0090091) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of presynapse assembly (GO:1905606) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of canonical Wnt signaling pathway (GO:0090090) 139 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of blood-brain barrier permeability (GO:1905605) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood-brain barrier permeability (GO:1905604) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood-brain barrier permeability (GO:1905603) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905602) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905601) 2 0 .00 - < 0.01 1.00E00 1.00E00 female meiosis chromosome separation (GO:0051309) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lung goblet cell differentiation (GO:1901249) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor-mediated endocytosis involved in cholesterol transport (GO:1905600) 5 0 .00 - < 0.01 1.00E00 1.00E00 male meiosis chromosome separation (GO:0051308) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lung ciliated cell differentiation (GO:1901248) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic chromosome separation (GO:0051307) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lung ciliated cell differentiation (GO:1901247) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid separation (GO:0051306) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lung ciliated cell differentiation (GO:1901246) 3 0 .00 - < 0.01 1.00E00 1.00E00 chromosome movement towards spindle pole (GO:0051305) 7 0 .00 - < 0.01 1.00E00 1.00E00 chromosome separation (GO:0051304) 11 0 .00 - < 0.01 1.00E00 1.00E00 establishment of chromosome localization (GO:0051303) 97 0 .03 - < 0.01 1.00E00 1.00E00 regulation of cell division (GO:0051302) 188 0 .05 - < 0.01 1.00E00 1.00E00 regulation of renal system process (GO:0098801) 23 0 .01 - < 0.01 1.00E00 1.00E00 cell division (GO:0051301) 523 0 .15 - < 0.01 1.00E00 1.00E00 regulation of dipeptide transport (GO:0090089) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oligopeptide transport (GO:0090088) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptide transport (GO:0090087) 211 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of protein deubiquitination (GO:0090086) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein deubiquitination (GO:0090085) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inclusion body assembly (GO:0090084) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inclusion body assembly (GO:0090083) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway (GO:0090080) 5 0 .00 - < 0.01 1.00E00 1.00E00 foam cell differentiation (GO:0090077) 6 0 .00 - < 0.01 1.00E00 1.00E00 relaxation of skeletal muscle (GO:0090076) 4 0 .00 - < 0.01 1.00E00 1.00E00 relaxation of muscle (GO:0090075) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein homodimerization activity (GO:0090074) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ribosome biogenesis (GO:0090071) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ribosome biogenesis (GO:0090070) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-1-mediated signaling pathway (GO:0070498) 22 0 .01 - < 0.01 1.00E00 1.00E00 unidimensional cell growth (GO:0009826) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of thrombin-activated receptor signaling pathway (GO:0070495) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thrombin-activated receptor signaling pathway (GO:0070494) 4 0 .00 - < 0.01 1.00E00 1.00E00 thrombin-activated receptor signaling pathway (GO:0070493) 11 0 .00 - < 0.01 1.00E00 1.00E00 alkaloid catabolic process (GO:0009822) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of non-canonical NF-kappaB signal transduction (GO:1901224) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of non-canonical NF-kappaB signal transduction (GO:1901223) 29 0 .01 - < 0.01 1.00E00 1.00E00 alkaloid metabolic process (GO:0009820) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of non-canonical NF-kappaB signal transduction (GO:1901222) 95 0 .03 - < 0.01 1.00E00 1.00E00 regulation of ribosome biogenesis (GO:0090069) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle process (GO:0090068) 262 0 .08 - < 0.01 1.00E00 1.00E00 regulation of thalamus size (GO:0090067) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anatomical structure size (GO:0090066) 506 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule nucleation (GO:0090063) 8 0 .00 - < 0.01 1.00E00 1.00E00 T cell aggregation (GO:0070489) 2 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil aggregation (GO:0070488) 2 0 .00 - < 0.01 1.00E00 1.00E00 monocyte aggregation (GO:0070487) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte aggregation (GO:0070486) 11 0 .00 - < 0.01 1.00E00 1.00E00 detection of hypoxia (GO:0070483) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to oxygen levels (GO:0070482) 334 0 .10 - < 0.01 1.00E00 1.00E00 flavonoid metabolic process (GO:0009812) 12 0 .00 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, non-stop decay (GO:0070481) 1 0 .00 - < 0.01 1.00E00 1.00E00 stilbene metabolic process (GO:0009810) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac chamber formation (GO:1901211) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac chamber formation (GO:1901210) 1 0 .00 - < 0.01 1.00E00 1.00E00 oocyte development (GO:0048599) 56 0 .02 - < 0.01 1.00E00 1.00E00 embryonic morphogenesis (GO:0048598) 595 0 .17 - < 0.01 1.00E00 1.00E00 post-embryonic camera-type eye morphogenesis (GO:0048597) 4 0 .00 - < 0.01 1.00E00 1.00E00 embryonic camera-type eye morphogenesis (GO:0048596) 26 0 .01 - < 0.01 1.00E00 1.00E00 camera-type eye morphogenesis (GO:0048593) 137 0 .04 - < 0.01 1.00E00 1.00E00 eye morphogenesis (GO:0048592) 166 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of cell migration involved in sprouting angiogenesis (GO:0090051) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell migration involved in sprouting angiogenesis (GO:0090050) 21 0 .01 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay (GO:0070478) 3 0 .00 - < 0.01 1.00E00 1.00E00 rRNA (guanine-N7)-methylation (GO:0070476) 2 0 .00 - < 0.01 1.00E00 1.00E00 rRNA base methylation (GO:0070475) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heart looping (GO:1901208) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of uterine smooth muscle contraction (GO:0070474) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heart looping (GO:1901207) 2 0 .00 - < 0.01 1.00E00 1.00E00 coumarin metabolic process (GO:0009804) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of uterine smooth muscle contraction (GO:0070473) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of uterine smooth muscle contraction (GO:0070472) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular matrix assembly (GO:1901203) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of extracellular matrix assembly (GO:1901202) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extracellular matrix assembly (GO:1901201) 20 0 .01 - < 0.01 1.00E00 1.00E00 response to stimulus (GO:0050896) 8218 3 2.40 + 1.25 6.89E-01 1.00E00 determination of affect (GO:0050894) 1 0 .00 - < 0.01 1.00E00 1.00E00 sensory processing (GO:0050893) 5 0 .00 - < 0.01 1.00E00 1.00E00 developmental growth (GO:0048589) 443 1 .13 + 7.74 1.22E-01 1.00E00 intestinal absorption (GO:0050892) 33 0 .01 - < 0.01 1.00E00 1.00E00 developmental cell growth (GO:0048588) 114 0 .03 - < 0.01 1.00E00 1.00E00 multicellular organismal-level water homeostasis (GO:0050891) 33 0 .01 - < 0.01 1.00E00 1.00E00 cognition (GO:0050890) 332 0 .10 - < 0.01 1.00E00 1.00E00 regulation of cell migration involved in sprouting angiogenesis (GO:0090049) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of response to stimulus (GO:0048585) 1711 1 .50 + 2.00 4.06E-01 1.00E00 positive regulation of response to stimulus (GO:0048584) 2286 0 .67 - < 0.01 1.00E00 1.00E00 regulation of response to stimulus (GO:0048583) 4079 1 1.19 - .84 1.00E00 1.00E00 positive regulation of deacetylase activity (GO:0090045) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tubulin deacetylation (GO:0090043) 7 0 .00 - < 0.01 1.00E00 1.00E00 tubulin deacetylation (GO:0090042) 3 0 .00 - < 0.01 1.00E00 1.00E00 plus-end specific microtubule depolymerization (GO:0070462) 1 0 .00 - < 0.01 1.00E00 1.00E00 thyroid-stimulating hormone secretion (GO:0070460) 2 0 .00 - < 0.01 1.00E00 1.00E00 endocrine process (GO:0050886) 57 0 .02 - < 0.01 1.00E00 1.00E00 neuromuscular process controlling balance (GO:0050885) 56 0 .02 - < 0.01 1.00E00 1.00E00 neuromuscular process controlling posture (GO:0050884) 19 0 .01 - < 0.01 1.00E00 1.00E00 musculoskeletal movement, spinal reflex action (GO:0050883) 2 0 .00 - < 0.01 1.00E00 1.00E00 voluntary musculoskeletal movement (GO:0050882) 7 0 .00 - < 0.01 1.00E00 1.00E00 musculoskeletal movement (GO:0050881) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein kinase C signaling (GO:0090037) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein kinase C signaling (GO:0090036) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chaperone-mediated protein complex assembly (GO:0090035) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chaperone-mediated protein complex assembly (GO:0090034) 1 0 .00 - < 0.01 1.00E00 1.00E00 long-day photoperiodism (GO:0048571) 1 0 .00 - < 0.01 1.00E00 1.00E00 notochord morphogenesis (GO:0048570) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of steroid hormone biosynthetic process (GO:0090032) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of steroid hormone biosynthetic process (GO:0090031) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of steroid hormone biosynthetic process (GO:0090030) 16 0 .00 - < 0.01 1.00E00 1.00E00 prolactin secretion (GO:0070459) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular detoxification of nitrogen compound (GO:0070458) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heme biosynthetic process (GO:0070455) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heme biosynthetic process (GO:0070453) 9 0 .00 - < 0.01 1.00E00 1.00E00 multicellular organismal movement (GO:0050879) 46 0 .01 - < 0.01 1.00E00 1.00E00 regulation of body fluid levels (GO:0050878) 371 0 .11 - < 0.01 1.00E00 1.00E00 nervous system process (GO:0050877) 1478 0 .43 - < 0.01 1.00E00 1.00E00 brown fat cell differentiation (GO:0050873) 33 0 .01 - < 0.01 1.00E00 1.00E00 white fat cell differentiation (GO:0050872) 17 0 .00 - < 0.01 1.00E00 1.00E00 embryonic organ development (GO:0048568) 454 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of B cell activation (GO:0050871) 86 0 .03 - < 0.01 1.00E00 1.00E00 ectodermal digestive tract morphogenesis (GO:0048567) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell activation (GO:0050870) 260 0 .08 - < 0.01 1.00E00 1.00E00 embryonic digestive tract development (GO:0048566) 33 0 .01 - < 0.01 1.00E00 1.00E00 digestive tract development (GO:0048565) 136 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte chemotaxis (GO:0090027) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte chemotaxis (GO:0090026) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of monocyte chemotaxis (GO:0090025) 31 0 .01 - < 0.01 1.00E00 1.00E00 embryonic organ morphogenesis (GO:0048562) 300 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil chemotaxis (GO:0090024) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of animal organ orientation (GO:0048561) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil chemotaxis (GO:0090023) 26 0 .01 - < 0.01 1.00E00 1.00E00 establishment of anatomical structure orientation (GO:0048560) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil chemotaxis (GO:0090022) 34 0 .01 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase V (GO:0001060) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oligodendrocyte progenitor proliferation (GO:0070447) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oligodendrocyte progenitor proliferation (GO:0070446) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oligodendrocyte progenitor proliferation (GO:0070445) 7 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte progenitor proliferation (GO:0070444) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of B cell activation (GO:0050869) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of T cell activation (GO:0050868) 134 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of cell activation (GO:0050867) 386 0 .11 - < 0.01 1.00E00 1.00E00 negative regulation of cell activation (GO:0050866) 220 0 .06 - < 0.01 1.00E00 1.00E00 regulation of cell activation (GO:0050865) 642 0 .19 - < 0.01 1.00E00 1.00E00 regulation of B cell activation (GO:0050864) 132 0 .04 - < 0.01 1.00E00 1.00E00 regulation of T cell activation (GO:0050863) 393 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of T cell receptor signaling pathway (GO:0050862) 19 0 .01 - < 0.01 1.00E00 1.00E00 transcription by RNA polymerase IV (GO:0001059) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell receptor signaling pathway (GO:0050861) 7 0 .00 - < 0.01 1.00E00 1.00E00 embryonic digestive tract morphogenesis (GO:0048557) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell receptor signaling pathway (GO:0050860) 29 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of pinocytosis (GO:0048550) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070434) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070433) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070432) 10 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-binding oligomerization domain containing 2 signaling pathway (GO:0070431) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070430) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of B cell receptor signaling pathway (GO:0050859) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) 37 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of T cell receptor signaling pathway (GO:0050856) 52 0 .02 - < 0.01 1.00E00 1.00E00 regulation of B cell receptor signaling pathway (GO:0050855) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of antigen receptor-mediated signaling pathway (GO:0050854) 70 0 .02 - < 0.01 1.00E00 1.00E00 B cell receptor signaling pathway (GO:0050853) 57 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of pinocytosis (GO:0048549) 7 0 .00 - < 0.01 1.00E00 1.00E00 T cell receptor signaling pathway (GO:0050852) 114 0 .03 - < 0.01 1.00E00 1.00E00 regulation of pinocytosis (GO:0048548) 12 0 .00 - < 0.01 1.00E00 1.00E00 antigen receptor-mediated signaling pathway (GO:0050851) 159 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-mediated signaling (GO:0050850) 60 0 .02 - < 0.01 1.00E00 1.00E00 primitive streak formation (GO:0090009) 11 0 .00 - < 0.01 1.00E00 1.00E00 digestive tract morphogenesis (GO:0048546) 49 0 .01 - < 0.01 1.00E00 1.00E00 response to steroid hormone (GO:0048545) 291 0 .08 - < 0.01 1.00E00 1.00E00 Peyer's patch development (GO:0048541) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070429) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070428) 4 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-binding oligomerization domain containing 1 signaling pathway (GO:0070427) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0070426) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0070425) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0070424) 15 0 .00 - < 0.01 1.00E00 1.00E00 antibiotic metabolic process (GO:0016999) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium-mediated signaling (GO:0050849) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of calcium-mediated signaling (GO:0050848) 99 0 .03 - < 0.01 1.00E00 1.00E00 progesterone receptor signaling pathway (GO:0050847) 13 0 .00 - < 0.01 1.00E00 1.00E00 bone marrow development (GO:0048539) 9 0 .00 - < 0.01 1.00E00 1.00E00 thymus development (GO:0048538) 50 0 .01 - < 0.01 1.00E00 1.00E00 mucosa-associated lymphoid tissue development (GO:0048537) 9 0 .00 - < 0.01 1.00E00 1.00E00 spleen development (GO:0048536) 41 0 .01 - < 0.01 1.00E00 1.00E00 lymph node development (GO:0048535) 21 0 .01 - < 0.01 1.00E00 1.00E00 hematopoietic or lymphoid organ development (GO:0048534) 103 0 .03 - < 0.01 1.00E00 1.00E00 anatomical structure arrangement (GO:0048532) 17 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cold (GO:0070417) 13 0 .00 - < 0.01 1.00E00 1.00E00 defense response to fungus (GO:0050832) 58 0 .02 - < 0.01 1.00E00 1.00E00 defense response to Gram-positive bacterium (GO:0050830) 121 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of viral process (GO:0048525) 76 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of viral process (GO:0048524) 64 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of cellular process (GO:0048523) 4996 1 1.46 - .69 1.00E00 1.00E00 positive regulation of cellular process (GO:0048522) 5807 1 1.69 - .59 1.00E00 1.00E00 negative regulation of behavior (GO:0048521) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of behavior (GO:0048520) 26 0 .01 - < 0.01 1.00E00 1.00E00 olefinic compound catabolic process (GO:0120256) 1 0 .00 - < 0.01 1.00E00 1.00E00 carbamoyl phosphate biosynthetic process (GO:0070409) 1 0 .00 - < 0.01 1.00E00 1.00E00 carbamoyl phosphate metabolic process (GO:0070408) 1 0 .00 - < 0.01 1.00E00 1.00E00 oxidation-dependent protein catabolic process (GO:0070407) 1 0 .00 - < 0.01 1.00E00 1.00E00 hydrocarbon catabolic process (GO:0120253) 4 0 .00 - < 0.01 1.00E00 1.00E00 hydrocarbon metabolic process (GO:0120252) 8 0 .00 - < 0.01 1.00E00 1.00E00 retrotransposition (GO:0032197) 5 0 .00 - < 0.01 1.00E00 1.00E00 transposition (GO:0032196) 7 0 .00 - < 0.01 1.00E00 1.00E00 ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate (GO:0032194) 2 0 .00 - < 0.01 1.00E00 1.00E00 defense response to Gram-negative bacterium (GO:0050829) 101 0 .03 - < 0.01 1.00E00 1.00E00 poly(A)+ mRNA export from nucleus (GO:0016973) 25 0 .01 - < 0.01 1.00E00 1.00E00 peptide antigen stabilization (GO:0050823) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of biological process (GO:0048519) 5208 1 1.52 - .66 1.00E00 1.00E00 peptide stabilization (GO:0050822) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of biological process (GO:0048518) 6117 1 1.78 - .56 6.77E-01 1.00E00 protein stabilization (GO:0050821) 237 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of coagulation (GO:0050820) 31 0 .01 - < 0.01 1.00E00 1.00E00 spermatid differentiation (GO:0048515) 238 0 .07 - < 0.01 1.00E00 1.00E00 blood vessel morphogenesis (GO:0048514) 444 0 .13 - < 0.01 1.00E00 1.00E00 animal organ development (GO:0048513) 2884 3 .84 + 3.57 3.95E-02 1.00E00 circadian behavior (GO:0048512) 25 0 .01 - < 0.01 1.00E00 1.00E00 rhythmic process (GO:0048511) 275 0 .08 - < 0.01 1.00E00 1.00E00 septin cytoskeleton organization (GO:0032185) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of coagulation (GO:0050819) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of coagulation (GO:0050818) 75 0 .02 - < 0.01 1.00E00 1.00E00 coagulation (GO:0050817) 192 0 .06 - < 0.01 1.00E00 1.00E00 doxorubicin transport (GO:1900753) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acyl-CoA biosynthetic process (GO:0050812) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of steroid biosynthetic process (GO:0050810) 81 0 .02 - < 0.01 1.00E00 1.00E00 regulation of timing of cell differentiation (GO:0048505) 12 0 .00 - < 0.01 1.00E00 1.00E00 (R)-carnitine transport (GO:1900749) 3 0 .00 - < 0.01 1.00E00 1.00E00 synapse organization (GO:0050808) 366 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of vascular endothelial growth factor signaling pathway (GO:1900748) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synapse organization (GO:0050807) 311 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of vascular endothelial growth factor signaling pathway (GO:1900747) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic transmission (GO:0050806) 147 0 .04 - < 0.01 1.00E00 1.00E00 regulation of vascular endothelial growth factor signaling pathway (GO:1900746) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic transmission (GO:0050805) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of p38MAPK cascade (GO:1900745) 26 0 .01 - < 0.01 1.00E00 1.00E00 modulation of chemical synaptic transmission (GO:0050804) 503 0 .15 - < 0.01 1.00E00 1.00E00 regulation of p38MAPK cascade (GO:1900744) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of synapse structure or activity (GO:0050803) 317 0 .09 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle, sleep (GO:0050802) 2 0 .00 - < 0.01 1.00E00 1.00E00 monoatomic ion homeostasis (GO:0050801) 523 0 .15 - < 0.01 1.00E00 1.00E00 protein localization to motile cilium (GO:0120229) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein deglycation (GO:0036525) 1 0 .00 - < 0.01 1.00E00 1.00E00 larynx development (GO:0120224) 2 0 .00 - < 0.01 1.00E00 1.00E00 larynx morphogenesis (GO:0120223) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blastocyst development (GO:0120222) 4 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of ciliary planar beating movement pattern (GO:0120221) 1 0 .00 - < 0.01 1.00E00 1.00E00 astrocyte-dopaminergic neuron signaling (GO:0036520) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900738) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900737) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipase C-activating G protein-coupled receptor signaling pathway (GO:1900736) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway (GO:1900731) 1 0 .00 - < 0.01 1.00E00 1.00E00 chemorepulsion of dopaminergic neuron axon (GO:0036518) 2 0 .00 - < 0.01 1.00E00 1.00E00 chemoattraction of serotonergic neuron axon (GO:0036517) 1 0 .00 - < 0.01 1.00E00 1.00E00 chemoattraction of dopaminergic neuron axon (GO:0036516) 1 0 .00 - < 0.01 1.00E00 1.00E00 serotonergic neuron axon guidance (GO:0036515) 5 0 .00 - < 0.01 1.00E00 1.00E00 dopaminergic neuron axon guidance (GO:0036514) 6 0 .00 - < 0.01 1.00E00 1.00E00 proacrosomal vesicle fusion (GO:0120211) 1 0 .00 - < 0.01 1.00E00 1.00E00 trimming of terminal mannose on C branch (GO:0036510) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway (GO:1900729) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation by symbiont of entry into host (GO:0075294) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of uterine smooth muscle relaxation (GO:1900721) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein alpha-1,2-demannosylation (GO:0036508) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein demannosylation (GO:0036507) 17 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of unfolded protein (GO:0036506) 4 0 .00 - < 0.01 1.00E00 1.00E00 ERAD pathway (GO:0036503) 95 0 .03 - < 0.01 1.00E00 1.00E00 formation of structure involved in a symbiotic process (GO:0044111) 1 0 .00 - < 0.01 1.00E00 1.00E00 ATF6-mediated unfolded protein response (GO:0036500) 8 0 .00 - < 0.01 1.00E00 1.00E00 activation of protein kinase B activity (GO:0032148) 14 0 .00 - < 0.01 1.00E00 1.00E00 activation of protein kinase activity (GO:0032147) 51 0 .01 - < 0.01 1.00E00 1.00E00 protein desumoylation (GO:0016926) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of uterine smooth muscle relaxation (GO:1900719) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein sumoylation (GO:0016925) 53 0 .02 - < 0.01 1.00E00 1.00E00 embryonic axis specification (GO:0000578) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of response to nutrient levels (GO:0032109) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to nutrient levels (GO:0032108) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to nutrient levels (GO:0032107) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of response to external stimulus (GO:0032103) 579 0 .17 - < 0.01 1.00E00 1.00E00 negative regulation of response to external stimulus (GO:0032102) 400 1 .12 + 8.58 1.11E-01 1.00E00 regulation of response to external stimulus (GO:0032101) 1113 1 .32 + 3.08 2.84E-01 1.00E00 positive regulation of appetite (GO:0032100) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell dedifferentiation (GO:0043697) 6 0 .00 - < 0.01 1.00E00 1.00E00 dedifferentiation (GO:0043696) 6 0 .00 - < 0.01 1.00E00 1.00E00 reverse cholesterol transport (GO:0043691) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein receptor activity (GO:1905599) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein receptor activity (GO:1905598) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein particle receptor binding (GO:1905597) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle receptor binding (GO:1905596) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of optical nerve axon regeneration (GO:1905592) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of optical nerve axon regeneration (GO:1905591) 1 0 .00 - < 0.01 1.00E00 1.00E00 centrosome separation (GO:0051299) 9 0 .00 - < 0.01 1.00E00 1.00E00 fibronectin fibril organization (GO:1905590) 2 0 .00 - < 0.01 1.00E00 1.00E00 centrosome duplication (GO:0051298) 39 0 .01 - < 0.01 1.00E00 1.00E00 post-translational protein modification (GO:0043687) 831 0 .24 - < 0.01 1.00E00 1.00E00 establishment of meiotic spindle orientation (GO:0051296) 4 0 .00 - < 0.01 1.00E00 1.00E00 global gene silencing by mRNA cleavage (GO:0098795) 3 0 .00 - < 0.01 1.00E00 1.00E00 co-translational protein modification (GO:0043686) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of meiotic spindle localization (GO:0051295) 8 0 .00 - < 0.01 1.00E00 1.00E00 establishment of spindle orientation (GO:0051294) 47 0 .01 - < 0.01 1.00E00 1.00E00 establishment of spindle localization (GO:0051293) 61 0 .02 - < 0.01 1.00E00 1.00E00 xenophagy (GO:0098792) 9 0 .00 - < 0.01 1.00E00 1.00E00 nuclear pore complex assembly (GO:0051292) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein heterooligomerization (GO:0051291) 31 0 .01 - < 0.01 1.00E00 1.00E00 protein heterotetramerization (GO:0051290) 16 0 .00 - < 0.01 1.00E00 1.00E00 induction of programmed cell death (GO:0012502) 1 0 .00 - < 0.01 1.00E00 1.00E00 programmed cell death (GO:0012501) 1095 0 .32 - < 0.01 1.00E00 1.00E00 negative regulation of outer hair cell apoptotic process (GO:1905586) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of outer hair cell apoptotic process (GO:1905585) 1 0 .00 - < 0.01 1.00E00 1.00E00 outer hair cell apoptotic process (GO:1905584) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of low-density lipoprotein particle clearance (GO:1905581) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein homotetramerization (GO:0051289) 66 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of ERBB3 signaling pathway (GO:1905580) 1 0 .00 - < 0.01 1.00E00 1.00E00 biofilm matrix disassembly (GO:0098786) 1 0 .00 - < 0.01 1.00E00 1.00E00 biofilm matrix organization (GO:0098784) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sequestering of calcium ion (GO:0051284) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sequestering of calcium ion (GO:0051283) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of sequestering of calcium ion (GO:0051282) 131 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of release of sequestered calcium ion into cytosol (GO:0051281) 43 0 .01 - < 0.01 1.00E00 1.00E00 response to mitochondrial depolarisation (GO:0098780) 6 0 .00 - < 0.01 1.00E00 1.00E00 exosomal secretion (GO:1990182) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of release of sequestered calcium ion into cytosol (GO:0051280) 12 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA 3'-end processing (GO:1990180) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ERBB3 signaling pathway (GO:1905578) 1 0 .00 - < 0.01 1.00E00 1.00E00 ganglioside GM1 transport to membrane (GO:1905572) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of release of sequestered calcium ion into cytosol (GO:0051279) 81 0 .02 - < 0.01 1.00E00 1.00E00 chromosome organization (GO:0051276) 418 0 .12 - < 0.01 1.00E00 1.00E00 skin epidermis development (GO:0098773) 119 0 .03 - < 0.01 1.00E00 1.00E00 inorganic ion homeostasis (GO:0098771) 443 0 .13 - < 0.01 1.00E00 1.00E00 protein localization to nucleoplasm (GO:1990173) 4 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor catabolic process (GO:1990172) 2 0 .00 - < 0.01 1.00E00 1.00E00 stress response to cadmium ion (GO:1990170) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular endothelial cell proliferation (GO:1905564) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vascular endothelial cell proliferation (GO:1905563) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular endothelial cell proliferation (GO:1905562) 26 0 .01 - < 0.01 1.00E00 1.00E00 lncRNA-mediated post-transcriptional gene silencing (GO:0000512) 2 0 .00 - < 0.01 1.00E00 1.00E00 stress response to copper ion (GO:1990169) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein K33-linked deubiquitination (GO:1990168) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein K27-linked deubiquitination (GO:1990167) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to site of double-strand break (GO:1990166) 16 0 .00 - < 0.01 1.00E00 1.00E00 recognition of apoptotic cell (GO:0043654) 7 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial fragmentation involved in apoptotic process (GO:0043653) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein tetramerization (GO:0051262) 100 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-7 (GO:0098761) 20 0 .01 - < 0.01 1.00E00 1.00E00 engulfment of apoptotic cell (GO:0043652) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein depolymerization (GO:0051261) 36 0 .01 - < 0.01 1.00E00 1.00E00 response to interleukin-7 (GO:0098760) 21 0 .01 - < 0.01 1.00E00 1.00E00 linoleic acid metabolic process (GO:0043651) 20 0 .01 - < 0.01 1.00E00 1.00E00 protein homooligomerization (GO:0051260) 207 0 .06 - < 0.01 1.00E00 1.00E00 dicarboxylic acid biosynthetic process (GO:0043650) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of blood vessel branching (GO:1905555) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel branching (GO:1905554) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood vessel branching (GO:1905553) 8 0 .00 - < 0.01 1.00E00 1.00E00 specification of symmetry (GO:0009799) 140 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to endoplasmic reticulum (GO:1905552) 3 0 .00 - < 0.01 1.00E00 1.00E00 axis specification (GO:0009798) 99 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-8 (GO:0098759) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to endoplasmic reticulum (GO:1905551) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein complex oligomerization (GO:0051259) 271 0 .08 - < 0.01 1.00E00 1.00E00 response to interleukin-8 (GO:0098758) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to endoplasmic reticulum (GO:1905550) 5 0 .00 - < 0.01 1.00E00 1.00E00 dicarboxylic acid catabolic process (GO:0043649) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein polymerization (GO:0051258) 102 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-21 (GO:0098757) 1 0 .00 - < 0.01 1.00E00 1.00E00 dicarboxylic acid metabolic process (GO:0043648) 95 0 .03 - < 0.01 1.00E00 1.00E00 meiotic spindle midzone assembly (GO:0051257) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-21 (GO:0098756) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle, embryonic (GO:0009794) 4 0 .00 - < 0.01 1.00E00 1.00E00 inositol phosphate metabolic process (GO:0043647) 30 0 .01 - < 0.01 1.00E00 1.00E00 mitotic spindle midzone assembly (GO:0051256) 11 0 .00 - < 0.01 1.00E00 1.00E00 spindle midzone assembly (GO:0051255) 14 0 .00 - < 0.01 1.00E00 1.00E00 detoxification (GO:0098754) 149 0 .04 - < 0.01 1.00E00 1.00E00 embryo development ending in birth or egg hatching (GO:0009792) 681 1 .20 + 5.04 1.83E-01 1.00E00 positive regulation of RNA metabolic process (GO:0051254) 1788 0 .52 - < 0.01 1.00E00 1.00E00 negative regulation of formation of translation preinitiation complex (GO:1901194) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic development (GO:0009791) 92 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of RNA metabolic process (GO:0051253) 1392 0 .41 - < 0.01 1.00E00 1.00E00 regulation of formation of translation preinitiation complex (GO:1901193) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryo development (GO:0009790) 1045 1 .30 + 3.28 2.69E-01 1.00E00 regulation of RNA metabolic process (GO:0051252) 3745 0 1.09 - < 0.01 6.00E-01 1.00E00 bone cell development (GO:0098751) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte activation (GO:0051251) 335 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte activation (GO:0051250) 170 0 .05 - < 0.01 1.00E00 1.00E00 cellular response to nutrient (GO:0031670) 40 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to phenylpropanoid (GO:1905546) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of abscisic acid-activated signaling pathway (GO:0009789) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar neuron development (GO:0098749) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of abscisic acid-activated signaling pathway (GO:0009787) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte activation (GO:0051249) 516 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of ephrin receptor signaling pathway (GO:1901189) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of asymmetric cell division (GO:0009786) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein metabolic process (GO:0051248) 583 0 .17 - < 0.01 1.00E00 1.00E00 blue light signaling pathway (GO:0009785) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein metabolic process (GO:0051247) 880 0 .26 - < 0.01 1.00E00 1.00E00 fast, calcium ion-dependent exocytosis of neurotransmitter (GO:0098746) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ephrin receptor signaling pathway (GO:1901187) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein metabolic process (GO:0051246) 1594 0 .46 - < 0.01 1.00E00 1.00E00 positive regulation of ERBB signaling pathway (GO:1901186) 30 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ERBB signaling pathway (GO:1901185) 33 0 .01 - < 0.01 1.00E00 1.00E00 cell aggregation (GO:0098743) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of ERBB signaling pathway (GO:1901184) 71 0 .02 - < 0.01 1.00E00 1.00E00 maintenance of translational fidelity (GO:1990145) 3 0 .00 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent ncRNA catabolic process (GO:0043634) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell adhesion via plasma-membrane adhesion molecules (GO:0098742) 262 0 .08 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to hypoxia (GO:1990144) 3 0 .00 - < 0.01 1.00E00 1.00E00 polyadenylation-dependent RNA catabolic process (GO:0043633) 2 0 .00 - < 0.01 1.00E00 1.00E00 modification-dependent macromolecule catabolic process (GO:0043632) 566 0 .17 - < 0.01 1.00E00 1.00E00 negative regulation of multicellular organismal process (GO:0051241) 1115 0 .33 - < 0.01 1.00E00 1.00E00 positive regulation of multicellular organismal process (GO:0051240) 1661 1 .48 + 2.07 3.96E-01 1.00E00 cellular response to nutrient levels (GO:0031669) 246 0 .07 - < 0.01 1.00E00 1.00E00 response to nutrient levels (GO:0031667) 509 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of lipopolysaccharide-mediated signaling pathway (GO:0031666) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipopolysaccharide-mediated signaling pathway (GO:0031664) 31 0 .01 - < 0.01 1.00E00 1.00E00 lipopolysaccharide-mediated signaling pathway (GO:0031663) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of postsynapse to nucleus signaling pathway (GO:1905539) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eukaryotic translation initiation factor 4F complex assembly (GO:1905537) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eukaryotic translation initiation factor 4F complex assembly (GO:1905535) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of L-leucine import across plasma membrane (GO:1905534) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of L-leucine import across plasma membrane (GO:1905533) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of L-leucine import across plasma membrane (GO:1905532) 3 0 .00 - < 0.01 1.00E00 1.00E00 import across plasma membrane (GO:0098739) 168 0 .05 - < 0.01 1.00E00 1.00E00 regulation of multicellular organismal process (GO:0051239) 2946 1 .86 + 1.16 1.00E00 1.00E00 protein insertion into plasma membrane (GO:0098737) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulatory ncRNA 3'-end processing (GO:0043628) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of the force of heart contraction (GO:0098736) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection extension (GO:1990138) 83 0 .02 - < 0.01 1.00E00 1.00E00 response to estrogen (GO:0043627) 69 0 .02 - < 0.01 1.00E00 1.00E00 establishment of RNA localization (GO:0051236) 163 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of the force of heart contraction (GO:0098735) 5 0 .00 - < 0.01 1.00E00 1.00E00 lycopene catabolic process (GO:1901176) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of location (GO:0051235) 92 0 .03 - < 0.01 1.00E00 1.00E00 macromolecule depalmitoylation (GO:0098734) 14 0 .00 - < 0.01 1.00E00 1.00E00 lycopene metabolic process (GO:1901175) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of localization (GO:0051234) 3981 0 1.16 - < 0.01 6.04E-01 1.00E00 macromolecule deacylation (GO:0098732) 30 0 .01 - < 0.01 1.00E00 1.00E00 epithelial cell apoptotic process involved in palatal shelf morphogenesis (GO:1990134) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic spindle elongation (GO:0051232) 1 0 .00 - < 0.01 1.00E00 1.00E00 cortical microtubule organization (GO:0043622) 9 0 .00 - < 0.01 1.00E00 1.00E00 spindle elongation (GO:0051231) 13 0 .00 - < 0.01 1.00E00 1.00E00 spindle disassembly (GO:0051230) 3 0 .00 - < 0.01 1.00E00 1.00E00 naphthalene catabolic process (GO:1901170) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heat generation (GO:0031652) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heat generation (GO:0031651) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heat generation (GO:0031650) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Golgi lumen acidification (GO:1905528) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Golgi lumen acidification (GO:1905526) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein autoubiquitination (GO:1905524) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage migration (GO:1905523) 29 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage migration (GO:1905522) 12 1 .00 + > 100 3.49E-03 1.00E00 regulation of macrophage migration (GO:1905521) 46 1 .01 + 74.57 1.33E-02 1.00E00 germline stem cell asymmetric division (GO:0098728) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of presynaptic active zone assembly (GO:1905520) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic spindle disassembly (GO:0051228) 3 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of cell number (GO:0098727) 125 0 .04 - < 0.01 1.00E00 1.00E00 symmetric cell division (GO:0098725) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural crest cell migration involved in autonomic nervous system development (GO:1901166) 6 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator (GO:1990127) 1 0 .00 - < 0.01 1.00E00 1.00E00 keratinocyte proliferation (GO:0043616) 27 0 .01 - < 0.01 1.00E00 1.00E00 spindle assembly (GO:0051225) 105 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of trophoblast cell migration (GO:1901165) 7 0 .00 - < 0.01 1.00E00 1.00E00 astrocyte cell migration (GO:0043615) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein transport (GO:0051224) 115 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of trophoblast cell migration (GO:1901164) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein transport (GO:0051223) 440 0 .13 - < 0.01 1.00E00 1.00E00 asymmetric stem cell division (GO:0098722) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of trophoblast cell migration (GO:1901163) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein transport (GO:0051222) 255 0 .07 - < 0.01 1.00E00 1.00E00 primary amino compound biosynthetic process (GO:1901162) 5 0 .00 - < 0.01 1.00E00 1.00E00 primary amino compound catabolic process (GO:1901161) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary amino compound metabolic process (GO:1901160) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of carbohydrate utilization (GO:0043610) 1 0 .00 - < 0.01 1.00E00 1.00E00 heat generation (GO:0031649) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein destabilization (GO:0031648) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein stability (GO:0031647) 386 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of nervous system process (GO:0031646) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of nervous system process (GO:0031645) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nervous system process (GO:0031644) 119 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of myelination (GO:0031643) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of myelination (GO:0031642) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myelination (GO:0031641) 47 0 .01 - < 0.01 1.00E00 1.00E00 killing of cells of another organism (GO:0031640) 114 0 .03 - < 0.01 1.00E00 1.00E00 regulation of presynaptic active zone assembly (GO:1905518) 1 0 .00 - < 0.01 1.00E00 1.00E00 macrophage migration (GO:1905517) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of fertilization (GO:1905516) 5 0 .00 - < 0.01 1.00E00 1.00E00 non-motile cilium assembly (GO:1905515) 57 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of short-term synaptic potentiation (GO:1905513) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of short-term synaptic potentiation (GO:1905512) 1 0 .00 - < 0.01 1.00E00 1.00E00 sodium ion import across plasma membrane (GO:0098719) 27 0 .01 - < 0.01 1.00E00 1.00E00 hexose mediated signaling (GO:0009757) 7 0 .00 - < 0.01 1.00E00 1.00E00 serine import across plasma membrane (GO:0098718) 3 0 .00 - < 0.01 1.00E00 1.00E00 xylulose 5-phosphate biosynthetic process (GO:1901159) 6 0 .00 - < 0.01 1.00E00 1.00E00 carbohydrate mediated signaling (GO:0009756) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of carbon utilization (GO:0043609) 3 0 .00 - < 0.01 1.00E00 1.00E00 hormone-mediated signaling pathway (GO:0009755) 151 0 .04 - < 0.01 1.00E00 1.00E00 cartilage development (GO:0051216) 176 0 .05 - < 0.01 1.00E00 1.00E00 B cell receptor apoptotic signaling pathway (GO:1990117) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to jasmonic acid (GO:0009753) 4 0 .00 - < 0.01 1.00E00 1.00E00 formamide metabolic process (GO:0043606) 4 0 .00 - < 0.01 1.00E00 1.00E00 ribosome-associated ubiquitin-dependent protein catabolic process (GO:1990116) 7 0 .00 - < 0.01 1.00E00 1.00E00 amide catabolic process (GO:0043605) 16 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase III assembly (GO:1990115) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to salicylic acid (GO:0009751) 1 0 .00 - < 0.01 1.00E00 1.00E00 amide biosynthetic process (GO:0043604) 155 0 .05 - < 0.01 1.00E00 1.00E00 L-glutamate import across plasma membrane (GO:0098712) 11 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase II core complex assembly (GO:1990114) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to fructose (GO:0009750) 9 0 .00 - < 0.01 1.00E00 1.00E00 amide metabolic process (GO:0043603) 408 0 .12 - < 0.01 1.00E00 1.00E00 iron ion import across plasma membrane (GO:0098711) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase I assembly (GO:1990113) 1 0 .00 - < 0.01 1.00E00 1.00E00 plasminogen activation (GO:0031639) 11 0 .00 - < 0.01 1.00E00 1.00E00 zymogen activation (GO:0031638) 32 0 .01 - < 0.01 1.00E00 1.00E00 adenylate cyclase-inhibiting opioid receptor signaling pathway (GO:0031635) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle fusion to presynaptic active zone membrane (GO:0031632) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle fusion to presynaptic active zone membrane (GO:0031630) 22 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to microtubule organizing center (GO:1905508) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of motile cilium assembly (GO:1905505) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of motile cilium assembly (GO:1905503) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to glucose (GO:0009749) 140 0 .04 - < 0.01 1.00E00 1.00E00 release of sequestered calcium ion into cytosol (GO:0051209) 57 0 .02 - < 0.01 1.00E00 1.00E00 D-glucose import across plasma membrane (GO:0098708) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to hexose (GO:0009746) 145 0 .04 - < 0.01 1.00E00 1.00E00 sequestering of calcium ion (GO:0051208) 5 0 .00 - < 0.01 1.00E00 1.00E00 gene expression involved in extracellular matrix organization (GO:1901148) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein linear deubiquitination (GO:1990108) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to sucrose (GO:0009744) 8 0 .00 - < 0.01 1.00E00 1.00E00 copper ion import across plasma membrane (GO:0098705) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to carbohydrate (GO:0009743) 177 0 .05 - < 0.01 1.00E00 1.00E00 protein insertion into membrane (GO:0051205) 47 0 .01 - < 0.01 1.00E00 1.00E00 carbohydrate import across plasma membrane (GO:0098704) 6 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell apoptotic process involved in nephron morphogenesis (GO:1901145) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein insertion into mitochondrial membrane (GO:0051204) 7 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion import across plasma membrane (GO:0098703) 28 0 .01 - < 0.01 1.00E00 1.00E00 insulin catabolic process (GO:1901143) 4 0 .00 - < 0.01 1.00E00 1.00E00 insulin metabolic process (GO:1901142) 16 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter loading into synaptic vesicle (GO:0098700) 8 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle fusion to presynaptic active zone membrane (GO:0031629) 10 0 .00 - < 0.01 1.00E00 1.00E00 telomeric loop formation (GO:0031627) 2 0 .00 - < 0.01 1.00E00 1.00E00 receptor internalization (GO:0031623) 71 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of fever generation (GO:0031622) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fever generation (GO:0031620) 9 0 .00 - < 0.01 1.00E00 1.00E00 carbohydrate derivative biosynthetic process (GO:1901137) 553 0 .16 - < 0.01 1.00E00 1.00E00 carbohydrate derivative catabolic process (GO:1901136) 201 0 .06 - < 0.01 1.00E00 1.00E00 carbohydrate derivative metabolic process (GO:1901135) 898 0 .26 - < 0.01 1.00E00 1.00E00 homologous chromosome orientation in meiotic metaphase I (GO:0031619) 2 0 .00 - < 0.01 1.00E00 1.00E00 gentamycin metabolic process (GO:1901128) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to hormone (GO:0009725) 849 0 .25 - < 0.01 1.00E00 1.00E00 detection of lipoteichoic acid (GO:0070392) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to lipoteichoic acid (GO:0070391) 11 0 .00 - < 0.01 1.00E00 1.00E00 tRNA-guanine transglycosylation (GO:0101030) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to endogenous stimulus (GO:0009719) 1243 0 .36 - < 0.01 1.00E00 1.00E00 mitotic nuclear membrane organization (GO:0101024) 10 0 .00 - < 0.01 1.00E00 1.00E00 Harderian gland development (GO:0070384) 4 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial cell proliferation (GO:0101023) 3 0 .00 - < 0.01 1.00E00 1.00E00 DNA cytosine deamination (GO:0070383) 9 0 .00 - < 0.01 1.00E00 1.00E00 catechol-containing compound biosynthetic process (GO:0009713) 19 0 .01 - < 0.01 1.00E00 1.00E00 catechol-containing compound metabolic process (GO:0009712) 47 0 .01 - < 0.01 1.00E00 1.00E00 synaptic vesicle membrane organization (GO:0048499) 15 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of animal organ identity (GO:0048496) 5 0 .00 - < 0.01 1.00E00 1.00E00 anterograde synaptic vesicle transport (GO:0048490) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ERK5 cascade (GO:0070378) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ERK5 cascade (GO:0070376) 3 0 .00 - < 0.01 1.00E00 1.00E00 ERK5 cascade (GO:0070375) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ERK1 and ERK2 cascade (GO:0070374) 193 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of ERK1 and ERK2 cascade (GO:0070373) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of ERK1 and ERK2 cascade (GO:0070372) 280 0 .08 - < 0.01 1.00E00 1.00E00 ERK1 and ERK2 cascade (GO:0070371) 52 0 .02 - < 0.01 1.00E00 1.00E00 cellular heat acclimation (GO:0070370) 5 0 .00 - < 0.01 1.00E00 1.00E00 activated T cell proliferation (GO:0050798) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of insulin secretion (GO:0050796) 176 0 .05 - < 0.01 1.00E00 1.00E00 regulation of behavior (GO:0050795) 76 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cellular process (GO:0050794) 11410 1 3.33 - .30 9.53E-02 1.00E00 regulation of developmental process (GO:0050793) 2443 0 .71 - < 0.01 1.00E00 1.00E00 synaptic vesicle transport (GO:0048489) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of viral process (GO:0050792) 142 0 .04 - < 0.01 1.00E00 1.00E00 synaptic vesicle endocytosis (GO:0048488) 51 0 .01 - < 0.01 1.00E00 1.00E00 regulation of catalytic activity (GO:0050790) 775 0 .23 - < 0.01 1.00E00 1.00E00 parasympathetic nervous system development (GO:0048486) 19 0 .01 - < 0.01 1.00E00 1.00E00 sympathetic nervous system development (GO:0048485) 22 0 .01 - < 0.01 1.00E00 1.00E00 enteric nervous system development (GO:0048484) 12 0 .00 - < 0.01 1.00E00 1.00E00 autonomic nervous system development (GO:0048483) 46 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte differentiation (GO:0070368) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte differentiation (GO:0070367) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte differentiation (GO:0070366) 2 0 .00 - < 0.01 1.00E00 1.00E00 hepatocyte differentiation (GO:0070365) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of biological process (GO:0050789) 11802 1 3.44 - .29 9.01E-02 1.00E00 detoxification of mercury ion (GO:0050787) 2 0 .00 - < 0.01 1.00E00 1.00E00 cocaine metabolic process (GO:0050783) 1 0 .00 - < 0.01 1.00E00 1.00E00 oogenesis (GO:0048477) 107 0 .03 - < 0.01 1.00E00 1.00E00 actin polymerization-dependent cell motility (GO:0070358) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of white fat cell proliferation (GO:0070352) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of white fat cell proliferation (GO:0070350) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA destabilization (GO:0050779) 82 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of immune response (GO:0050778) 683 0 .20 - < 0.01 1.00E00 1.00E00 negative regulation of immune response (GO:0050777) 206 0 .06 - < 0.01 1.00E00 1.00E00 regulation of immune response (GO:0050776) 1013 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of dendrite morphogenesis (GO:0050775) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of dendrite morphogenesis (GO:0050774) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendrite development (GO:0050773) 101 0 .03 - < 0.01 1.00E00 1.00E00 cell maturation (GO:0048469) 192 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of axonogenesis (GO:0050772) 74 0 .02 - < 0.01 1.00E00 1.00E00 cell development (GO:0048468) 2282 0 .67 - < 0.01 1.00E00 1.00E00 negative regulation of axonogenesis (GO:0050771) 54 0 .02 - < 0.01 1.00E00 1.00E00 regulation of axonogenesis (GO:0050770) 143 0 .04 - < 0.01 1.00E00 1.00E00 PERK-mediated unfolded protein response (GO:0036499) 8 0 .00 - < 0.01 1.00E00 1.00E00 IRE1-mediated unfolded protein response (GO:0036498) 8 0 .00 - < 0.01 1.00E00 1.00E00 mucociliary clearance (GO:0120197) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translation initiation in response to endoplasmic reticulum stress (GO:0036494) 1 0 .00 - < 0.01 1.00E00 1.00E00 tight junction organization (GO:0120193) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of translation in response to endoplasmic reticulum stress (GO:0036493) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fat cell proliferation (GO:0070346) 4 0 .00 - < 0.01 1.00E00 1.00E00 tight junction assembly (GO:0120192) 57 0 .02 - < 0.01 1.00E00 1.00E00 eiF2alpha phosphorylation in response to endoplasmic reticulum stress (GO:0036492) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fat cell proliferation (GO:0070345) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of termination of RNA polymerase II transcription (GO:0120191) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation initiation in response to endoplasmic reticulum stress (GO:0036491) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fat cell proliferation (GO:0070344) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid secretion (GO:0120190) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation in response to endoplasmic reticulum stress (GO:0036490) 11 0 .00 - < 0.01 1.00E00 1.00E00 white fat cell proliferation (GO:0070343) 2 0 .00 - < 0.01 1.00E00 1.00E00 brown fat cell proliferation (GO:0070342) 2 0 .00 - < 0.01 1.00E00 1.00E00 fat cell proliferation (GO:0070341) 7 0 .00 - < 0.01 1.00E00 1.00E00 detection of bacterial lipopeptide (GO:0070340) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurogenesis (GO:0050769) 229 0 .07 - < 0.01 1.00E00 1.00E00 negative regulation of neurogenesis (GO:0050768) 135 0 .04 - < 0.01 1.00E00 1.00E00 regulation of neurogenesis (GO:0050767) 363 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of phagocytosis (GO:0050766) 73 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of phagocytosis (GO:0050765) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of phagocytosis (GO:0050764) 101 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of bile acid secretion (GO:0120189) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bile acid secretion (GO:0120188) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to chromatin (GO:0120187) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to chromatin (GO:0120186) 6 0 .00 - < 0.01 1.00E00 1.00E00 ventral trunk neural crest cell migration (GO:0036486) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to bacterial lipopeptide (GO:0070339) 7 0 .00 - < 0.01 1.00E00 1.00E00 trunk neural crest cell migration (GO:0036484) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of molecular function (GO:0044093) 768 0 .22 - < 0.01 1.00E00 1.00E00 positive regulation of focal adhesion disassembly (GO:0120183) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0036483) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of molecular function (GO:0044092) 487 0 .14 - < 0.01 1.00E00 1.00E00 regulation of focal adhesion disassembly (GO:0120182) 6 0 .00 - < 0.01 1.00E00 1.00E00 membrane biogenesis (GO:0044091) 68 0 .02 - < 0.01 1.00E00 1.00E00 focal adhesion disassembly (GO:0120181) 2 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:0036481) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vacuole organization (GO:0044090) 25 0 .01 - < 0.01 1.00E00 1.00E00 cell-substrate junction disassembly (GO:0120180) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuron intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0036480) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular component biogenesis (GO:0044089) 510 0 .15 - < 0.01 1.00E00 1.00E00 adherens junction disassembly (GO:0120179) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vacuole organization (GO:0044088) 61 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cellular component biogenesis (GO:0044087) 1024 0 .30 - < 0.01 1.00E00 1.00E00 cellular component biogenesis (GO:0044085) 2746 0 .80 - < 0.01 1.00E00 1.00E00 triglyceride homeostasis (GO:0070328) 42 0 .01 - < 0.01 1.00E00 1.00E00 thyroid hormone transport (GO:0070327) 12 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by BDNF (GO:0099191) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glyoxal (GO:0036471) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein metabolic process (GO:0050748) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein metabolic process (GO:0050747) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein metabolic process (GO:0050746) 14 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic cytoskeleton organization (GO:0099188) 23 0 .01 - < 0.01 1.00E00 1.00E00 presynaptic cytoskeleton organization (GO:0099187) 6 0 .00 - < 0.01 1.00E00 1.00E00 detection of cold stimulus involved in thermoception (GO:0120169) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of hot stimulus involved in thermoception (GO:0120168) 1 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic intermediate filament cytoskeleton organization (GO:0099185) 3 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle recycling via endosome (GO:0036466) 6 0 .00 - < 0.01 1.00E00 1.00E00 trans-synaptic signaling by BDNF, modulating synaptic transmission (GO:0099183) 2 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle recycling (GO:0036465) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of G0 to G1 transition (GO:0070318) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G0 to G1 transition (GO:0070317) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cold-induced thermogenesis (GO:0120163) 48 0 .01 - < 0.01 1.00E00 1.00E00 regulation of G0 to G1 transition (GO:0070316) 36 0 .01 - < 0.01 1.00E00 1.00E00 zinc ion import into synaptic vesicle (GO:0099180) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cold-induced thermogenesis (GO:0120162) 101 0 .03 - < 0.01 1.00E00 1.00E00 TRAIL-activated apoptotic signaling pathway (GO:0036462) 9 0 .00 - < 0.01 1.00E00 1.00E00 G1 to G0 transition involved in cell differentiation (GO:0070315) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cold-induced thermogenesis (GO:0120161) 151 0 .04 - < 0.01 1.00E00 1.00E00 regulation of monoatomic anion transport (GO:0044070) 15 0 .00 - < 0.01 1.00E00 1.00E00 G1 to G0 transition (GO:0070314) 16 0 .00 - < 0.01 1.00E00 1.00E00 olefin metabolic process (GO:1900673) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-tyrosine phosphorylation (GO:0050732) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-tyrosine phosphorylation (GO:0050731) 66 0 .02 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-tyrosine phosphorylation (GO:0050730) 99 0 .03 - < 0.01 1.00E00 1.00E00 regulation of synaptic membrane adhesion (GO:0099179) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retrograde trans-synaptic signaling by endocanabinoid (GO:0099178) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of trans-synaptic signaling (GO:0099177) 504 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of collagen catabolic process (GO:0120158) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynapse organization (GO:0099175) 146 0 .04 - < 0.01 1.00E00 1.00E00 regulation of presynapse organization (GO:0099174) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of respiratory system process (GO:0044065) 16 0 .00 - < 0.01 1.00E00 1.00E00 lens fiber cell morphogenesis (GO:0070309) 6 0 .00 - < 0.01 1.00E00 1.00E00 postsynapse organization (GO:0099173) 114 0 .03 - < 0.01 1.00E00 1.00E00 presynapse organization (GO:0099172) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ERBB4 signaling pathway (GO:0120154) 2 0 .00 - < 0.01 1.00E00 1.00E00 lens fiber cell development (GO:0070307) 14 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic modulation of chemical synaptic transmission (GO:0099171) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of excretion (GO:0044062) 11 0 .00 - < 0.01 1.00E00 1.00E00 lens fiber cell differentiation (GO:0070306) 29 0 .01 - < 0.01 1.00E00 1.00E00 postsynaptic modulation of chemical synaptic transmission (GO:0099170) 33 0 .01 - < 0.01 1.00E00 1.00E00 response to cGMP (GO:0070305) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endocrine process (GO:0044060) 42 1 .01 + 81.67 1.22E-02 1.00E00 positive regulation of stress-activated protein kinase signaling cascade (GO:0070304) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of appetite (GO:0032099) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stress-activated protein kinase signaling cascade (GO:0070303) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of appetite (GO:0032098) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of stress-activated protein kinase signaling cascade (GO:0070302) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of response to food (GO:0032097) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hydrogen peroxide (GO:0070301) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of response to food (GO:0032096) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to food (GO:0032095) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to food (GO:0032094) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of inflammatory response (GO:0050729) 153 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of inflammatory response (GO:0050728) 175 1 .05 + 19.60 5.00E-02 1.00E00 positive regulation of protein binding (GO:0032092) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of inflammatory response (GO:0050727) 402 1 .12 + 8.53 1.12E-01 1.00E00 negative regulation of protein binding (GO:0032091) 54 0 .02 - < 0.01 1.00E00 1.00E00 regulation of digestive system process (GO:0044058) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of system process (GO:0044057) 559 1 .16 + 6.14 1.52E-01 1.00E00 myofibroblast differentiation (GO:0036446) 5 0 .00 - < 0.01 1.00E00 1.00E00 synaptic signaling by nitric oxide (GO:0099163) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuronal stem cell division (GO:0036445) 2 0 .00 - < 0.01 1.00E00 1.00E00 calcium import into the mitochondrion (GO:0036444) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of presynaptic dense core granule exocytosis (GO:0099161) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of NF-kappaB transcription factor activity (GO:0032088) 65 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein secretion (GO:0050714) 150 0 .04 - < 0.01 1.00E00 1.00E00 regulation of modification of postsynaptic structure (GO:0099159) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of recycling endosome localization within postsynapse (GO:0099158) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of lens transparency (GO:0036438) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter receptor transport, endosome to postsynaptic membrane (GO:0099152) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic density assembly (GO:0099151) 17 0 .00 - < 0.01 1.00E00 1.00E00 glucan metabolic process (GO:0044042) 63 0 .02 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic specialization assembly (GO:0099150) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of endodeoxyribonuclease activity (GO:0032079) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endodeoxyribonuclease activity (GO:0032078) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of deoxyribonuclease activity (GO:0032077) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of deoxyribonuclease activity (GO:0032076) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nuclease activity (GO:0032075) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclease activity (GO:0032074) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein secretion (GO:0050709) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein secretion (GO:0050708) 266 0 .08 - < 0.01 1.00E00 1.00E00 regulation of restriction endodeoxyribonuclease activity (GO:0032072) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endodeoxyribonuclease activity (GO:0032071) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic neurotransmitter receptor internalization (GO:0099149) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of exocytic insertion of neurotransmitter receptor to postsynaptic membrane (GO:0099145) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to zinc ion starvation (GO:0120127) 9 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic actin cytoskeleton organization (GO:0099140) 5 0 .00 - < 0.01 1.00E00 1.00E00 bleb assembly (GO:0032060) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gene expression via chromosomal CpG island demethylation (GO:0044029) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gene expression via chromosomal CpG island methylation (GO:0044027) 16 0 .00 - < 0.01 1.00E00 1.00E00 T cell meandering migration (GO:0120117) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucagon processing (GO:0120116) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA stabilization (GO:0036416) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tRNA stability (GO:0036415) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation in response to stress (GO:0032058) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of translational initiation in response to stress (GO:0032057) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translation in response to stress (GO:0032056) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of translation in response to stress (GO:0032055) 7 0 .00 - < 0.01 1.00E00 1.00E00 ciliary basal body organization (GO:0032053) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monocyte aggregation (GO:1900625) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of monocyte aggregation (GO:1900623) 3 0 .00 - < 0.01 1.00E00 1.00E00 acetate ester biosynthetic process (GO:1900620) 3 0 .00 - < 0.01 1.00E00 1.00E00 somato-dendritic dopamine secretion (GO:0099123) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiolipin biosynthetic process (GO:0032049) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiolipin metabolic process (GO:0032048) 11 0 .00 - < 0.01 1.00E00 1.00E00 acetate ester metabolic process (GO:1900619) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial DNA catabolic process (GO:0032043) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial DNA metabolic process (GO:0032042) 19 0 .01 - < 0.01 1.00E00 1.00E00 microtubule-based protein transport (GO:0099118) 14 0 .00 - < 0.01 1.00E00 1.00E00 tRNA 5'-end processing (GO:0099116) 16 0 .00 - < 0.01 1.00E00 1.00E00 box H/ACA sno(s)RNA 3'-end processing (GO:0000495) 2 0 .00 - < 0.01 1.00E00 1.00E00 box C/D sno(s)RNA 3'-end processing (GO:0000494) 3 0 .00 - < 0.01 1.00E00 1.00E00 box H/ACA snoRNP assembly (GO:0000493) 2 0 .00 - < 0.01 1.00E00 1.00E00 microtubule-based transport (GO:0099111) 220 0 .06 - < 0.01 1.00E00 1.00E00 box C/D snoRNP assembly (GO:0000492) 9 0 .00 - < 0.01 1.00E00 1.00E00 small nucleolar ribonucleoprotein complex assembly (GO:0000491) 11 0 .00 - < 0.01 1.00E00 1.00E00 potassium channel activating, G protein-coupled receptor signaling pathway (GO:0099109) 1 0 .00 - < 0.01 1.00E00 1.00E00 ion channel modulating, G protein-coupled receptor signaling pathway (GO:0099105) 8 0 .00 - < 0.01 1.00E00 1.00E00 maturation of 5S rRNA (GO:0000481) 1 0 .00 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000480) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to magnesium ion (GO:0032026) 19 0 .01 - < 0.01 1.00E00 1.00E00 response to cobalt ion (GO:0032025) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of insulin secretion (GO:0032024) 89 0 .03 - < 0.01 1.00E00 1.00E00 trypsinogen activation (GO:0032023) 1 0 .00 - < 0.01 1.00E00 1.00E00 ISG15-protein conjugation (GO:0032020) 6 0 .00 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000479) 16 0 .00 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000472) 5 0 .00 - < 0.01 1.00E00 1.00E00 maturation of LSU-rRNA (GO:0000470) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of ARF protein signal transduction (GO:0032014) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ARF protein signal transduction (GO:0032012) 21 0 .01 - < 0.01 1.00E00 1.00E00 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000467) 7 0 .00 - < 0.01 1.00E00 1.00E00 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000466) 22 0 .01 - < 0.01 1.00E00 1.00E00 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000463) 17 0 .00 - < 0.01 1.00E00 1.00E00 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000462) 34 0 .01 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000461) 1 0 .00 - < 0.01 1.00E00 1.00E00 maturation of 5.8S rRNA (GO:0000460) 33 0 .01 - < 0.01 1.00E00 1.00E00 tetrahydrofolate interconversion (GO:0035999) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of TOR signaling (GO:0032008) 77 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of TOR signaling (GO:0032007) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of TOR signaling (GO:0032006) 154 0 .04 - < 0.01 1.00E00 1.00E00 detection of muscle stretch (GO:0035995) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to muscle stretch (GO:0035994) 25 0 .01 - < 0.01 1.00E00 1.00E00 deltoid tuberosity development (GO:0035993) 3 0 .00 - < 0.01 1.00E00 1.00E00 tendon formation (GO:0035992) 2 0 .00 - < 0.01 1.00E00 1.00E00 tendon cell differentiation (GO:0035990) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fatty acid beta-oxidation (GO:0032000) 11 0 .00 - < 0.01 1.00E00 1.00E00 enzyme-directed rRNA pseudouridine synthesis (GO:0000455) 4 0 .00 - < 0.01 1.00E00 1.00E00 snoRNA guided rRNA pseudouridine synthesis (GO:0000454) 3 0 .00 - < 0.01 1.00E00 1.00E00 rRNA 2'-O-methylation (GO:0000451) 3 0 .00 - < 0.01 1.00E00 1.00E00 tendon development (GO:0035989) 5 0 .00 - < 0.01 1.00E00 1.00E00 chondrocyte proliferation (GO:0035988) 15 0 .00 - < 0.01 1.00E00 1.00E00 endodermal cell differentiation (GO:0035987) 46 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to trichostatin A (GO:0035984) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to trichostatin A (GO:0035983) 2 0 .00 - < 0.01 1.00E00 1.00E00 hemoglobin metabolic process (GO:0020027) 11 0 .00 - < 0.01 1.00E00 1.00E00 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000448) 2 0 .00 - < 0.01 1.00E00 1.00E00 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (GO:0000447) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of branching morphogenesis of a nerve (GO:1905492) 2 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic specialization assembly (GO:0098698) 15 0 .00 - < 0.01 1.00E00 1.00E00 skin morphogenesis (GO:0043589) 12 0 .00 - < 0.01 1.00E00 1.00E00 skin development (GO:0043588) 285 0 .08 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter receptor localization to postsynaptic specialization membrane (GO:0098696) 19 0 .01 - < 0.01 1.00E00 1.00E00 tongue morphogenesis (GO:0043587) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein deglycosylation involved in glycoprotein catabolic process (GO:0035977) 3 0 .00 - < 0.01 1.00E00 1.00E00 tongue development (GO:0043586) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle budding from presynaptic endocytic zone membrane (GO:0098694) 1 0 .00 - < 0.01 1.00E00 1.00E00 nose morphogenesis (GO:0043585) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle cycle (GO:0098693) 15 0 .00 - < 0.01 1.00E00 1.00E00 nose development (GO:0043584) 16 0 .00 - < 0.01 1.00E00 1.00E00 ear development (GO:0043583) 230 0 .07 - < 0.01 1.00E00 1.00E00 aggrephagy (GO:0035973) 10 0 .00 - < 0.01 1.00E00 1.00E00 calcium-dependent self proteolysis (GO:1990092) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-histidine dephosphorylation (GO:0035971) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nerve growth factor stimulus (GO:1990090) 51 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-threonine dephosphorylation (GO:0035970) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of motor neuron migration (GO:1905485) 1 0 .00 - < 0.01 1.00E00 1.00E00 carbon catabolite activation of transcription from RNA polymerase II promoter (GO:0000436) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter by galactose (GO:0000435) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of motor neuron migration (GO:1905483) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription from RNA polymerase II promoter by glucose (GO:0000432) 5 0 .00 - < 0.01 1.00E00 1.00E00 prosthetic group metabolic process (GO:0051189) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter by galactose (GO:0000431) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to nerve growth factor (GO:1990089) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of transcription from RNA polymerase II promoter by glucose (GO:0000430) 5 0 .00 - < 0.01 1.00E00 1.00E00 nuclear matrix organization (GO:0043578) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to topologically incorrect protein (GO:0035967) 92 0 .03 - < 0.01 1.00E00 1.00E00 regulation of respiratory gaseous exchange (GO:0043576) 24 0 .01 - < 0.01 1.00E00 1.00E00 lens fiber cell apoptotic process (GO:1990086) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to topologically incorrect protein (GO:0035966) 143 0 .04 - < 0.01 1.00E00 1.00E00 cardiolipin acyl-chain remodeling (GO:0035965) 5 0 .00 - < 0.01 1.00E00 1.00E00 peroxisomal transport (GO:0043574) 22 0 .01 - < 0.01 1.00E00 1.00E00 COPI-coated vesicle budding (GO:0035964) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-13 (GO:0035963) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-13 (GO:0035962) 7 0 .00 - < 0.01 1.00E00 1.00E00 vitamin transport (GO:0051180) 56 0 .02 - < 0.01 1.00E00 1.00E00 maintenance of DNA repeat elements (GO:0043570) 6 0 .00 - < 0.01 1.00E00 1.00E00 carbon catabolite regulation of transcription from RNA polymerase II promoter (GO:0000429) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to membrane (GO:1905477) 105 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to membrane (GO:1905476) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to membrane (GO:1905475) 196 0 .06 - < 0.01 1.00E00 1.00E00 pexophagy (GO:0000425) 16 0 .00 - < 0.01 1.00E00 1.00E00 mitophagy (GO:0000423) 57 0 .02 - < 0.01 1.00E00 1.00E00 autophagy of mitochondrion (GO:0000422) 75 0 .02 - < 0.01 1.00E00 1.00E00 localization (GO:0051179) 4523 0 1.32 - < 0.01 3.50E-01 1.00E00 negative regulation of insulin-like growth factor receptor signaling pathway (GO:0043569) 7 0 .00 - < 0.01 1.00E00 1.00E00 cartilage homeostasis (GO:1990079) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) 13 0 .00 - < 0.01 1.00E00 1.00E00 meiotic sister chromatid cohesion (GO:0051177) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of sulfur metabolic process (GO:0051176) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sulfur metabolic process (GO:0051175) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphorus metabolic process (GO:0051174) 698 0 .20 - < 0.01 1.00E00 1.00E00 polyuridylation-dependent mRNA catabolic process (GO:1990074) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nitrogen levels (GO:0043562) 12 0 .00 - < 0.01 1.00E00 1.00E00 entry receptor-mediated virion attachment to host cell (GO:0098670) 1 0 .00 - < 0.01 1.00E00 1.00E00 import into nucleus (GO:0051170) 123 0 .04 - < 0.01 1.00E00 1.00E00 wybutosine biosynthetic process (GO:0031591) 6 0 .00 - < 0.01 1.00E00 1.00E00 wybutosine metabolic process (GO:0031590) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein peptidyl-prolyl isomerization (GO:0000413) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell apoptotic process (GO:1905461) 9 0 .00 - < 0.01 1.00E00 1.00E00 nuclear transport (GO:0051169) 250 0 .07 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell apoptotic process (GO:1905460) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by galactose (GO:0000411) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear export (GO:0051168) 131 0 .04 - < 0.01 1.00E00 1.00E00 regulation of translational initiation in response to stress (GO:0043558) 10 0 .00 - < 0.01 1.00E00 1.00E00 xylulose 5-phosphate metabolic process (GO:0051167) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation in response to oxidative stress (GO:0043556) 1 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled serotonin receptor signaling pathway (GO:0098664) 19 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA surveillance (GO:0035946) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation in response to stress (GO:0043555) 21 0 .01 - < 0.01 1.00E00 1.00E00 xylitol metabolic process (GO:0051164) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial ncRNA surveillance (GO:0035945) 1 0 .00 - < 0.01 1.00E00 1.00E00 inorganic cation transmembrane transport (GO:0098662) 683 0 .20 - < 0.01 1.00E00 1.00E00 inorganic anion transmembrane transport (GO:0098661) 132 0 .04 - < 0.01 1.00E00 1.00E00 inorganic ion transmembrane transport (GO:0098660) 776 0 .23 - < 0.01 1.00E00 1.00E00 xylitol catabolic process (GO:0051160) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipid kinase activity (GO:0043550) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell-substrate adhesion (GO:0031589) 184 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031587) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity (GO:0031585) 4 0 .00 - < 0.01 1.00E00 1.00E00 activation of phospholipase D activity (GO:0031584) 1 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase D-activating G protein-coupled receptor signaling pathway (GO:0031583) 2 0 .00 - < 0.01 1.00E00 1.00E00 hemidesmosome assembly (GO:0031581) 6 0 .00 - < 0.01 1.00E00 1.00E00 membrane raft distribution (GO:0031580) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell apoptotic process (GO:1905459) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphoid progenitor cell differentiation (GO:1905458) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcription by galactose (GO:0000409) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lymphoid progenitor cell differentiation (GO:1905457) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphoid progenitor cell differentiation (GO:1905456) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid progenitor cell differentiation (GO:1905454) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myeloid progenitor cell differentiation (GO:1905453) 3 0 .00 - < 0.01 1.00E00 1.00E00 phenylpropanoid metabolic process (GO:0009698) 7 0 .00 - < 0.01 1.00E00 1.00E00 inorganic cation import across plasma membrane (GO:0098659) 108 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905451) 1 0 .00 - < 0.01 1.00E00 1.00E00 inorganic anion import across plasma membrane (GO:0098658) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of signal transduction in absence of ligand (GO:1901099) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905450) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of kinase activity (GO:0043549) 351 0 .10 - < 0.01 1.00E00 1.00E00 import into cell (GO:0098657) 696 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of autophagosome maturation (GO:1901098) 7 0 .00 - < 0.01 1.00E00 1.00E00 monoatomic anion transmembrane transport (GO:0098656) 149 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of autophagosome maturation (GO:1901097) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of GTPase activity (GO:0043547) 112 0 .03 - < 0.01 1.00E00 1.00E00 glucose 6-phosphate metabolic process (GO:0051156) 23 0 .01 - < 0.01 1.00E00 1.00E00 monoatomic cation transmembrane transport (GO:0098655) 698 0 .20 - < 0.01 1.00E00 1.00E00 regulation of autophagosome maturation (GO:1901096) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of striated muscle cell differentiation (GO:0051155) 42 0 .01 - < 0.01 1.00E00 1.00E00 ethylene metabolic process (GO:0009692) 1 0 .00 - < 0.01 1.00E00 1.00E00 molybdopterin cofactor metabolic process (GO:0043545) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of striated muscle cell differentiation (GO:0051154) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of striated muscle cell differentiation (GO:0051153) 84 0 .02 - < 0.01 1.00E00 1.00E00 corticosterone secretion (GO:0035934) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein acylation (GO:0043543) 64 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell differentiation (GO:0051152) 16 0 .00 - < 0.01 1.00E00 1.00E00 glucocorticoid secretion (GO:0035933) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell migration (GO:0043542) 83 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell differentiation (GO:0051151) 17 0 .00 - < 0.01 1.00E00 1.00E00 aldosterone secretion (GO:0035932) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell differentiation (GO:0051150) 36 0 .01 - < 0.01 1.00E00 1.00E00 activation of protein kinase C activity (GO:1990051) 2 0 .00 - < 0.01 1.00E00 1.00E00 mineralocorticoid secretion (GO:0035931) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane raft organization (GO:0031579) 28 0 .01 - < 0.01 1.00E00 1.00E00 corticosteroid hormone secretion (GO:0035930) 4 0 .00 - < 0.01 1.00E00 1.00E00 spindle checkpoint signaling (GO:0031577) 31 0 .01 - < 0.01 1.00E00 1.00E00 mitotic intra-S DNA damage checkpoint signaling (GO:0031573) 17 0 .00 - < 0.01 1.00E00 1.00E00 mitotic G1 DNA damage checkpoint signaling (GO:0031571) 16 0 .00 - < 0.01 1.00E00 1.00E00 DNA integrity checkpoint signaling (GO:0031570) 109 0 .03 - < 0.01 1.00E00 1.00E00 regulation of Fc-gamma receptor signaling pathway involved in phagocytosis (GO:1905449) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905448) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905447) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial ATP synthesis coupled electron transport (GO:1905446) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of clathrin coat assembly (GO:1905445) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of clathrin coat assembly (GO:1905443) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of muscle cell differentiation (GO:0051149) 67 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of muscle cell differentiation (GO:0051148) 62 0 .02 - < 0.01 1.00E00 1.00E00 retrograde neuronal dense core vesicle transport (GO:1990049) 5 0 .00 - < 0.01 1.00E00 1.00E00 steroid hormone secretion (GO:0035929) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle cell differentiation (GO:0051147) 141 0 .04 - < 0.01 1.00E00 1.00E00 anterograde neuronal dense core vesicle transport (GO:1990048) 4 0 .00 - < 0.01 1.00E00 1.00E00 rRNA import into mitochondrion (GO:0035928) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel endothelial cell migration (GO:0043537) 36 0 .01 - < 0.01 1.00E00 1.00E00 striated muscle cell differentiation (GO:0051146) 220 0 .06 - < 0.01 1.00E00 1.00E00 indoleacetic acid metabolic process (GO:0009683) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA import into mitochondrion (GO:0035927) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of blood vessel endothelial cell migration (GO:0043536) 55 0 .02 - < 0.01 1.00E00 1.00E00 smooth muscle cell differentiation (GO:0051145) 36 0 .01 - < 0.01 1.00E00 1.00E00 stress-induced mitochondrial fusion (GO:1990046) 2 0 .00 - < 0.01 1.00E00 1.00E00 induced systemic resistance (GO:0009682) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood vessel endothelial cell migration (GO:0043535) 93 0 .03 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell migration (GO:0043534) 37 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to lipid droplet (GO:1990044) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to vascular endothelial growth factor stimulus (GO:0035924) 87 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of NK T cell proliferation (GO:0051142) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of relaxation of smooth muscle (GO:1901082) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of NK T cell proliferation (GO:0051141) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of relaxation of smooth muscle (GO:1901081) 1 0 .00 - < 0.01 1.00E00 1.00E00 foramen ovale closure (GO:0035922) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NK T cell proliferation (GO:0051140) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of relaxation of smooth muscle (GO:1901080) 2 0 .00 - < 0.01 1.00E00 1.00E00 desmosome disassembly (GO:0035921) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of retrograde trans-synaptic signaling by neuropeptide (GO:1905433) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retrograde trans-synaptic signaling by neuropeptide (GO:1905432) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of relaxation of muscle (GO:1901079) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glycine (GO:1905430) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of NK T cell differentiation (GO:0051138) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of relaxation of muscle (GO:1901078) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of relaxation of muscle (GO:1901077) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NK T cell differentiation (GO:0051136) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of engulfment of apoptotic cell (GO:1901076) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of NK T cell activation (GO:0051135) 9 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion import into sarcoplasmic reticulum (GO:1990036) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuron apoptotic process (GO:0043525) 68 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of NK T cell activation (GO:0051134) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of engulfment of apoptotic cell (GO:1901074) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron apoptotic process (GO:0043524) 168 0 .05 - < 0.01 1.00E00 1.00E00 regulation of NK T cell activation (GO:0051133) 12 0 .00 - < 0.01 1.00E00 1.00E00 glucosamine-containing compound biosynthetic process (GO:1901073) 2 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion export across plasma membrane (GO:1990034) 5 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle cell differentiation (GO:0035914) 61 0 .02 - < 0.01 1.00E00 1.00E00 regulation of neuron apoptotic process (GO:0043523) 251 0 .07 - < 0.01 1.00E00 1.00E00 NK T cell activation (GO:0051132) 7 0 .00 - < 0.01 1.00E00 1.00E00 glucosamine-containing compound catabolic process (GO:1901072) 10 0 .00 - < 0.01 1.00E00 1.00E00 chaperone-mediated protein complex assembly (GO:0051131) 23 0 .01 - < 0.01 1.00E00 1.00E00 glucosamine-containing compound metabolic process (GO:1901071) 25 0 .01 - < 0.01 1.00E00 1.00E00 dorsal aorta morphogenesis (GO:0035912) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular component organization (GO:0051130) 1116 0 .33 - < 0.01 1.00E00 1.00E00 ascending aorta morphogenesis (GO:0035910) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of termination of DNA-templated transcription (GO:0031554) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031550) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to glycine (GO:1905429) 3 0 .00 - < 0.01 1.00E00 1.00E00 trans-Golgi network membrane organization (GO:0098629) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular component organization (GO:0051129) 691 0 .20 - < 0.01 1.00E00 1.00E00 regulation of myosin II filament organization (GO:0043519) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular component organization (GO:0051128) 2467 0 .72 - < 0.01 1.00E00 1.00E00 guanosine-containing compound metabolic process (GO:1901068) 1 0 .00 - < 0.01 1.00E00 1.00E00 vasomotion (GO:1990029) 1 0 .00 - < 0.01 1.00E00 1.00E00 aorta morphogenesis (GO:0035909) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin nucleation (GO:0051127) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043517) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of actin nucleation (GO:0051126) 9 0 .00 - < 0.01 1.00E00 1.00E00 dorsal aorta development (GO:0035907) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of actin nucleation (GO:0051125) 42 0 .01 - < 0.01 1.00E00 1.00E00 descending aorta development (GO:0035906) 1 0 .00 - < 0.01 1.00E00 1.00E00 synaptic assembly at neuromuscular junction (GO:0051124) 4 0 .00 - < 0.01 1.00E00 1.00E00 ascending aorta development (GO:0035905) 5 0 .00 - < 0.01 1.00E00 1.00E00 RNA polymerase II preinitiation complex assembly (GO:0051123) 63 0 .02 - < 0.01 1.00E00 1.00E00 aorta development (GO:0035904) 62 0 .02 - < 0.01 1.00E00 1.00E00 hepoxilin biosynthetic process (GO:0051122) 8 0 .00 - < 0.01 1.00E00 1.00E00 hepoxilin metabolic process (GO:0051121) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to immobilization stress (GO:0035902) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031549) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to isolation stress (GO:0035900) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of brain-derived neurotrophic factor receptor signaling pathway (GO:0031548) 3 0 .00 - < 0.01 1.00E00 1.00E00 brain-derived neurotrophic factor receptor signaling pathway (GO:0031547) 53 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule exocytosis (GO:1905415) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dense core granule exocytosis (GO:1905413) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of JUN kinase activity (GO:0043508) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of JUN kinase activity (GO:0043507) 25 0 .01 - < 0.01 1.00E00 1.00E00 anatomical structure morphogenesis (GO:0009653) 2262 1 .66 + 1.52 5.03E-01 1.00E00 regulation of JUN kinase activity (GO:0043506) 35 0 .01 - < 0.01 1.00E00 1.00E00 response to salt stress (GO:0009651) 19 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial DNA repair (GO:0043504) 8 0 .00 - < 0.01 1.00E00 1.00E00 sarcosine catabolic process (GO:1901053) 1 0 .00 - < 0.01 1.00E00 1.00E00 UV protection (GO:0009650) 12 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle fiber adaptation (GO:0043503) 4 0 .00 - < 0.01 1.00E00 1.00E00 sarcosine metabolic process (GO:1901052) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle adaptation (GO:0043502) 83 0 .02 - < 0.01 1.00E00 1.00E00 skeletal muscle adaptation (GO:0043501) 13 0 .00 - < 0.01 1.00E00 1.00E00 muscle adaptation (GO:0043500) 39 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of exit from mitosis (GO:0031536) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of creatine transmembrane transporter activity (GO:1905408) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905404) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905403) 2 0 .00 - < 0.01 1.00E00 1.00E00 entrainment of circadian clock (GO:0009649) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of activated CD8-positive, alpha-beta T cell apoptotic process (GO:1905402) 3 0 .00 - < 0.01 1.00E00 1.00E00 photoperiodism (GO:0009648) 27 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell adhesion (GO:0098609) 550 0 .16 - < 0.01 1.00E00 1.00E00 response to absence of light (GO:0009646) 2 0 .00 - < 0.01 1.00E00 1.00E00 retinal cell apoptotic process (GO:1990009) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to low light intensity stimulus (GO:0009645) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to high light intensity (GO:0009644) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to light intensity (GO:0009642) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA binding (GO:0051101) 68 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of binding (GO:0051100) 89 0 .03 - < 0.01 1.00E00 1.00E00 amyloid fibril formation (GO:1990000) 28 0 .01 - < 0.01 1.00E00 1.00E00 ruffle organization (GO:0031529) 27 0 .01 - < 0.01 1.00E00 1.00E00 response to blue light (GO:0009637) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to toxic substance (GO:0009636) 257 0 .07 - < 0.01 1.00E00 1.00E00 response to herbicide (GO:0009635) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of L-glutamine import across plasma membrane (GO:1901036) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of L-glutamine import across plasma membrane (GO:1901034) 1 0 .00 - < 0.01 1.00E00 1.00E00 cold acclimation (GO:0009631) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to reactive oxygen species (GO:1901032) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to reactive oxygen species (GO:1901031) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901030) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to gravity (GO:0009629) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to abiotic stimulus (GO:0009628) 1129 0 .33 - < 0.01 1.00E00 1.00E00 sarcoplasmic reticulum calcium ion transport (GO:0070296) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901029) 15 0 .00 - < 0.01 1.00E00 1.00E00 renal water absorption (GO:0070295) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway (GO:1901028) 24 0 .01 - < 0.01 1.00E00 1.00E00 renal sodium ion absorption (GO:0070294) 13 0 .00 - < 0.01 1.00E00 1.00E00 dextrin catabolic process (GO:1901027) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to nematode (GO:0009624) 10 0 .00 - < 0.01 1.00E00 1.00E00 renal absorption (GO:0070293) 36 0 .01 - < 0.01 1.00E00 1.00E00 ripoptosome assembly involved in necroptotic process (GO:1901026) 2 0 .00 - < 0.01 1.00E00 1.00E00 N-acylphosphatidylethanolamine metabolic process (GO:0070292) 9 0 .00 - < 0.01 1.00E00 1.00E00 N-acylethanolamine metabolic process (GO:0070291) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to fungus (GO:0009620) 69 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transmembrane transporter activity (GO:1901021) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion transmembrane transporter activity (GO:1901020) 20 0 .01 - < 0.01 1.00E00 1.00E00 subtelomeric heterochromatin formation (GO:0031509) 9 0 .00 - < 0.01 1.00E00 1.00E00 pericentric heterochromatin formation (GO:0031508) 4 0 .00 - < 0.01 1.00E00 1.00E00 heterochromatin formation (GO:0031507) 142 0 .04 - < 0.01 1.00E00 1.00E00 protein-containing complex localization (GO:0031503) 159 0 .05 - < 0.01 1.00E00 1.00E00 response to bacterium (GO:0009617) 697 0 .20 - < 0.01 1.00E00 1.00E00 axonemal dynein complex assembly (GO:0070286) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of calcium ion transmembrane transporter activity (GO:1901019) 52 0 .02 - < 0.01 1.00E00 1.00E00 pigment cell development (GO:0070285) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of potassium ion transmembrane transporter activity (GO:1901018) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to virus (GO:0009615) 384 0 .11 - < 0.01 1.00E00 1.00E00 negative regulation of potassium ion transmembrane transporter activity (GO:1901017) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of potassium ion transmembrane transporter activity (GO:1901016) 30 0 .01 - < 0.01 1.00E00 1.00E00 response to mechanical stimulus (GO:0009612) 227 0 .07 - < 0.01 1.00E00 1.00E00 response to wounding (GO:0009611) 449 0 .13 - < 0.01 1.00E00 1.00E00 intermediate mesodermal cell differentiation (GO:0048392) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermediate mesoderm formation (GO:0048391) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermediate mesoderm morphogenesis (GO:0048390) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to symbiotic bacterium (GO:0009609) 6 0 .00 - < 0.01 1.00E00 1.00E00 extracellular matrix constituent secretion (GO:0070278) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to symbiont (GO:0009608) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte adhesion to arterial endothelial cell (GO:1904999) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to biotic stimulus (GO:0009607) 1474 0 .43 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte adhesion to arterial endothelial cell (GO:1904998) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte adhesion to arterial endothelial cell (GO:1904997) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to external stimulus (GO:0009605) 1953 0 .57 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte adhesion to vascular endothelial cell (GO:1904996) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte adhesion to vascular endothelial cell (GO:1904995) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte adhesion to vascular endothelial cell (GO:1904994) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fermentation (GO:1901003) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:1904992) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway (GO:1904990) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to salt stress (GO:1901000) 4 0 .00 - < 0.01 1.00E00 1.00E00 intermediate mesoderm development (GO:0048389) 2 0 .00 - < 0.01 1.00E00 1.00E00 endosomal lumen acidification (GO:0048388) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of defense response to virus by host (GO:0050691) 45 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of retinoic acid receptor signaling pathway (GO:0048387) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of retinoic acid receptor signaling pathway (GO:0048386) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retinoic acid receptor signaling pathway (GO:0048385) 16 0 .00 - < 0.01 1.00E00 1.00E00 retinoic acid receptor signaling pathway (GO:0048384) 21 0 .01 - < 0.01 1.00E00 1.00E00 mesendoderm development (GO:0048382) 10 0 .00 - < 0.01 1.00E00 1.00E00 pyroptotic inflammatory response (GO:0070269) 33 0 .01 - < 0.01 1.00E00 1.00E00 cornification (GO:0070268) 8 0 .00 - < 0.01 1.00E00 1.00E00 necroptotic process (GO:0070266) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of quinolinate biosynthetic process (GO:1904985) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine dephosphorylation (GO:0070262) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of quinolinate biosynthetic process (GO:1904984) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycine import into mitochondrion (GO:1904983) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of defense response to virus by host (GO:0050689) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endosome organization (GO:1904980) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of defense response to virus (GO:0050688) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of defense response to virus (GO:0050687) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA processing (GO:0050686) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA processing (GO:0050685) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mRNA processing (GO:0050684) 133 0 .04 - < 0.01 1.00E00 1.00E00 regulation of lateral mesodermal cell fate specification (GO:0048378) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell proliferation (GO:0050680) 136 0 .04 - < 0.01 1.00E00 1.00E00 lateral mesodermal cell differentiation (GO:0048371) 2 0 .00 - < 0.01 1.00E00 1.00E00 lateral mesoderm formation (GO:0048370) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mucus secretion (GO:0070257) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endosome organization (GO:1904979) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mucus secretion (GO:0070256) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endosome organization (GO:1904978) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mucus secretion (GO:0070255) 9 0 .00 - < 0.01 1.00E00 1.00E00 lymphatic endothelial cell migration (GO:1904977) 3 0 .00 - < 0.01 1.00E00 1.00E00 mucus secretion (GO:0070254) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to bleomycin (GO:1904976) 2 0 .00 - < 0.01 1.00E00 1.00E00 somatostatin secretion (GO:0070253) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to bleomycin (GO:1904975) 4 0 .00 - < 0.01 1.00E00 1.00E00 actin-mediated cell contraction (GO:0070252) 82 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of viral translation (GO:1904973) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of viral translation (GO:1904971) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation (GO:0050679) 201 0 .06 - < 0.01 1.00E00 1.00E00 brush border assembly (GO:1904970) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell proliferation (GO:0050678) 359 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of urothelial cell proliferation (GO:0050677) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of urothelial cell proliferation (GO:0050675) 1 0 .00 - < 0.01 1.00E00 1.00E00 urothelial cell proliferation (GO:0050674) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation (GO:0050673) 178 0 .05 - < 0.01 1.00E00 1.00E00 lateral mesoderm morphogenesis (GO:0048369) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte proliferation (GO:0050672) 91 0 .03 - < 0.01 1.00E00 1.00E00 lateral mesoderm development (GO:0048368) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte proliferation (GO:0050671) 146 0 .04 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte proliferation (GO:0050670) 242 0 .07 - < 0.01 1.00E00 1.00E00 TCR signalosome assembly (GO:0036399) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-lysine crotonylation (GO:0120094) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell apoptotic process (GO:0070247) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-lysine crotonylation (GO:0120093) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of thymocyte apoptotic process (GO:0070245) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of thymocyte apoptotic process (GO:0070244) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thymocyte apoptotic process (GO:0070243) 15 0 .00 - < 0.01 1.00E00 1.00E00 thymocyte apoptotic process (GO:0070242) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of activated T cell autonomous cell death (GO:0070241) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytochrome-c oxidase activity (GO:1904960) 2 0 .00 - < 0.01 1.00E00 1.00E00 homocysteine metabolic process (GO:0050667) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of homocysteine metabolic process (GO:0050666) 1 0 .00 - < 0.01 1.00E00 1.00E00 hydrogen peroxide biosynthetic process (GO:0050665) 10 0 .00 - < 0.01 1.00E00 1.00E00 paraxial mesoderm structural organization (GO:0048352) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of activated T cell autonomous cell death (GO:0070239) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytochrome-c oxidase activity (GO:1904959) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of activation-induced cell death of T cells (GO:0070236) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of midbrain dopaminergic neuron differentiation (GO:1904958) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of activation-induced cell death of T cells (GO:0070235) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell apoptotic process (GO:0070234) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of midbrain dopaminergic neuron differentiation (GO:1904956) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell apoptotic process (GO:0070233) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of T cell apoptotic process (GO:0070232) 42 0 .01 - < 0.01 1.00E00 1.00E00 T cell apoptotic process (GO:0070231) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte apoptotic process (GO:0070230) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of protein localization (GO:1904951) 325 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of protein localization (GO:1904950) 131 0 .04 - < 0.01 1.00E00 1.00E00 RNA transport (GO:0050658) 161 0 .05 - < 0.01 1.00E00 1.00E00 nucleic acid transport (GO:0050657) 161 0 .05 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan metabolic process (GO:0050655) 13 0 .00 - < 0.01 1.00E00 1.00E00 chondroitin sulfate proteoglycan metabolic process (GO:0050654) 32 0 .01 - < 0.01 1.00E00 1.00E00 chondroitin sulfate proteoglycan biosynthetic process, chain elongation (GO:0050653) 4 0 .00 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan biosynthetic process, chain elongation (GO:0050652) 1 0 .00 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan biosynthetic process (GO:0050651) 9 0 .00 - < 0.01 1.00E00 1.00E00 chondroitin sulfate proteoglycan biosynthetic process (GO:0050650) 25 0 .01 - < 0.01 1.00E00 1.00E00 paraxial mesodermal cell fate commitment (GO:0048343) 2 0 .00 - < 0.01 1.00E00 1.00E00 paraxial mesodermal cell differentiation (GO:0048342) 2 0 .00 - < 0.01 1.00E00 1.00E00 paraxial mesoderm formation (GO:0048341) 7 0 .00 - < 0.01 1.00E00 1.00E00 paraxial mesoderm morphogenesis (GO:0048340) 10 0 .00 - < 0.01 1.00E00 1.00E00 cell adhesion involved in sprouting angiogenesis (GO:0120078) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcitriol biosynthetic process from calciol (GO:0036378) 5 0 .00 - < 0.01 1.00E00 1.00E00 angiogenic sprout fusion (GO:0120077) 1 0 .00 - < 0.01 1.00E00 1.00E00 sodium ion export across plasma membrane (GO:0036376) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte apoptotic process (GO:0070229) 38 0 .01 - < 0.01 1.00E00 1.00E00 calcium export from the mitochondrion (GO:0099093) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte apoptotic process (GO:0070228) 61 0 .02 - < 0.01 1.00E00 1.00E00 lymphocyte apoptotic process (GO:0070227) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of pyloric antrum smooth muscle contraction (GO:0120072) 1 0 .00 - < 0.01 1.00E00 1.00E00 midbrain dopaminergic neuron differentiation (GO:1904948) 13 0 .00 - < 0.01 1.00E00 1.00E00 opsin transport (GO:0036372) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pyloric antrum smooth muscle contraction (GO:0120071) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to T-tubule (GO:0036371) 1 0 .00 - < 0.01 1.00E00 1.00E00 sulfide oxidation, using sulfide:quinone oxidoreductase (GO:0070221) 3 0 .00 - < 0.01 1.00E00 1.00E00 paraxial mesoderm development (GO:0048339) 19 0 .01 - < 0.01 1.00E00 1.00E00 mesoderm structural organization (GO:0048338) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesodermal cell fate specification (GO:0048337) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesodermal cell differentiation (GO:0048333) 27 0 .01 - < 0.01 1.00E00 1.00E00 mesoderm morphogenesis (GO:0048332) 72 0 .02 - < 0.01 1.00E00 1.00E00 axonal transport of messenger ribonucleoprotein complex (GO:0099088) 1 0 .00 - < 0.01 1.00E00 1.00E00 cone photoresponse recovery (GO:0036368) 1 0 .00 - < 0.01 1.00E00 1.00E00 light adaption (GO:0036367) 3 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic specialization organization (GO:0099084) 31 0 .01 - < 0.01 1.00E00 1.00E00 sensory neuron migration (GO:1904937) 1 0 .00 - < 0.01 1.00E00 1.00E00 interneuron migration (GO:1904936) 15 0 .00 - < 0.01 1.00E00 1.00E00 protein auto-ADP-ribosylation (GO:0070213) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation in midbrain (GO:1904935) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein poly-ADP-ribosylation (GO:0070212) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation in midbrain (GO:1904934) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation in midbrain (GO:1904933) 3 0 .00 - < 0.01 1.00E00 1.00E00 axial mesodermal cell fate specification (GO:0048327) 1 0 .00 - < 0.01 1.00E00 1.00E00 axial mesodermal cell fate commitment (GO:0048322) 1 0 .00 - < 0.01 1.00E00 1.00E00 axial mesodermal cell differentiation (GO:0048321) 1 0 .00 - < 0.01 1.00E00 1.00E00 axial mesoderm formation (GO:0048320) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal potassium excretion (GO:0036359) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of small intestinal transit (GO:0120058) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion-derived vesicle mediated transport (GO:0099075) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of small intestinal transit (GO:0120057) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion to lysosome vesicle-mediated transport (GO:0099074) 3 0 .00 - < 0.01 1.00E00 1.00E00 large intestinal transit (GO:0120056) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein heterotrimerization (GO:0070208) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic membrane neurotransmitter receptor levels (GO:0099072) 71 0 .02 - < 0.01 1.00E00 1.00E00 intestinal motility (GO:0120054) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein homotrimerization (GO:0070207) 15 0 .00 - < 0.01 1.00E00 1.00E00 protein trimerization (GO:0070206) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein localization to telomere (GO:0070203) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein localization to chromosome (GO:0070202) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein localization (GO:0070201) 534 0 .16 - < 0.01 1.00E00 1.00E00 establishment of protein localization to telomere (GO:0070200) 7 0 .00 - < 0.01 1.00E00 1.00E00 axial mesoderm morphogenesis (GO:0048319) 4 0 .00 - < 0.01 1.00E00 1.00E00 axial mesoderm development (GO:0048318) 9 0 .00 - < 0.01 1.00E00 1.00E00 Golgi inheritance (GO:0048313) 12 0 .00 - < 0.01 1.00E00 1.00E00 intracellular distribution of mitochondria (GO:0048312) 8 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion distribution (GO:0048311) 20 0 .01 - < 0.01 1.00E00 1.00E00 postsynapse assembly (GO:0099068) 22 0 .01 - < 0.01 1.00E00 1.00E00 snRNA (adenine-N6)-methylation (GO:0120049) 2 0 .00 - < 0.01 1.00E00 1.00E00 stereocilium maintenance (GO:0120045) 4 0 .00 - < 0.01 1.00E00 1.00E00 platelet maturation (GO:0036345) 2 0 .00 - < 0.01 1.00E00 1.00E00 platelet morphogenesis (GO:0036344) 25 0 .01 - < 0.01 1.00E00 1.00E00 psychomotor behavior (GO:0036343) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage proliferation (GO:0120042) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-anal tail morphogenesis (GO:0036342) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage proliferation (GO:0120041) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage proliferation (GO:0120040) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of protein-containing complex localization to telomere (GO:1904914) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein-containing complex localization to telomere (GO:1904913) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of RNA localization to telomere (GO:1904911) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of RNA localization to telomere (GO:1904910) 1 0 .00 - < 0.01 1.00E00 1.00E00 organelle inheritance (GO:0048308) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of isotype switching to IgG isotypes (GO:0048304) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of isotype switching to IgG isotypes (GO:0048302) 15 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane bounded cell projection morphogenesis (GO:0120039) 505 0 .15 - < 0.01 1.00E00 1.00E00 lymphocyte adhesion to endothelial cell of high endothelial venule (GO:0036339) 1 0 .00 - < 0.01 1.00E00 1.00E00 Fas signaling pathway (GO:0036337) 2 0 .00 - < 0.01 1.00E00 1.00E00 presynapse assembly (GO:0099054) 22 0 .01 - < 0.01 1.00E00 1.00E00 plasma membrane bounded cell projection organization (GO:0120036) 1186 0 .35 - < 0.01 1.00E00 1.00E00 dendritic cell migration (GO:0036336) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane bounded cell projection organization (GO:0120035) 638 0 .19 - < 0.01 1.00E00 1.00E00 intestinal stem cell homeostasis (GO:0036335) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of plasma membrane bounded cell projection assembly (GO:0120034) 113 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of plasma membrane bounded cell projection assembly (GO:0120033) 40 0 .01 - < 0.01 1.00E00 1.00E00 hepatocyte homeostasis (GO:0036333) 1 0 .00 - < 0.01 1.00E00 1.00E00 vesicle scission (GO:0099050) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane bounded cell projection assembly (GO:0120032) 203 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric (GO:1904908) 2 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane bounded cell projection assembly (GO:0120031) 445 0 .13 - < 0.01 1.00E00 1.00E00 regulation of maintenance of mitotic sister chromatid cohesion, telomeric (GO:1904907) 2 0 .00 - < 0.01 1.00E00 1.00E00 avascular cornea development in camera-type eye (GO:0036331) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell-matrix adhesion via fibronectin (GO:1904906) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell-matrix adhesion via fibronectin (GO:1904905) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell-matrix adhesion via fibronectin (GO:1904904) 8 0 .00 - < 0.01 1.00E00 1.00E00 ESCRT III complex disassembly (GO:1904903) 10 0 .00 - < 0.01 1.00E00 1.00E00 ESCRT III complex assembly (GO:1904902) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of purine nucleotide metabolic process (GO:1900544) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of purine nucleotide metabolic process (GO:1900543) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of purine nucleotide metabolic process (GO:1900542) 85 0 .02 - < 0.01 1.00E00 1.00E00 clathrin coat assembly involved in endocytosis (GO:0099049) 1 0 .00 - < 0.01 1.00E00 1.00E00 clearance of foreign intracellular nucleic acids (GO:0099046) 6 0 .00 - < 0.01 1.00E00 1.00E00 vesicle tethering to endoplasmic reticulum (GO:0099044) 2 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-3 signaling pathway (GO:0036325) 1 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-2 signaling pathway (GO:0036324) 6 0 .00 - < 0.01 1.00E00 1.00E00 vesicle tethering to Golgi (GO:0099041) 5 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor-1 signaling pathway (GO:0036323) 49 0 .01 - < 0.01 1.00E00 1.00E00 ceramide translocation (GO:0099040) 2 0 .00 - < 0.01 1.00E00 1.00E00 ghrelin secretion (GO:0036321) 2 0 .00 - < 0.01 1.00E00 1.00E00 palmitic acid biosynthetic process (GO:1900535) 1 0 .00 - < 0.01 1.00E00 1.00E00 palmitic acid metabolic process (GO:1900533) 1 0 .00 - < 0.01 1.00E00 1.00E00 sphingolipid translocation (GO:0099039) 4 0 .00 - < 0.01 1.00E00 1.00E00 SREBP-SCAP complex retention in endoplasmic reticulum (GO:0036316) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to sterol (GO:0036315) 23 0 .01 - < 0.01 1.00E00 1.00E00 response to sterol (GO:0036314) 33 0 .01 - < 0.01 1.00E00 1.00E00 intermembrane sphingolipid transfer (GO:0120012) 1 0 .00 - < 0.01 1.00E00 1.00E00 intermembrane lipid transfer (GO:0120009) 36 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to M-band (GO:0036309) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamatergic neuron differentiation (GO:0120008) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glutamatergic neuron differentiation (GO:0120007) 1 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane invagination (GO:0099024) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glutamatergic neuron differentiation (GO:0120006) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic heart tube elongation (GO:0036306) 1 0 .00 - < 0.01 1.00E00 1.00E00 ameloblast differentiation (GO:0036305) 9 0 .00 - < 0.01 1.00E00 1.00E00 vesicle tethering (GO:0099022) 32 0 .01 - < 0.01 1.00E00 1.00E00 umbilical cord morphogenesis (GO:0036304) 2 0 .00 - < 0.01 1.00E00 1.00E00 lymph vessel morphogenesis (GO:0036303) 19 0 .01 - < 0.01 1.00E00 1.00E00 atrioventricular canal development (GO:0036302) 13 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein localization at cell tip (GO:0099017) 1 0 .00 - < 0.01 1.00E00 1.00E00 mRNA splicing, via spliceosome (GO:0000398) 245 0 .07 - < 0.01 1.00E00 1.00E00 mRNA 5'-splice site recognition (GO:0000395) 6 0 .00 - < 0.01 1.00E00 1.00E00 RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) 14 0 .00 - < 0.01 1.00E00 1.00E00 spliceosomal conformational changes to generate catalytic conformation (GO:0000393) 5 0 .00 - < 0.01 1.00E00 1.00E00 neuronal dense core vesicle exocytosis (GO:0099011) 6 0 .00 - < 0.01 1.00E00 1.00E00 modification of postsynaptic structure (GO:0099010) 17 0 .00 - < 0.01 1.00E00 1.00E00 spliceosomal complex disassembly (GO:0000390) 2 0 .00 - < 0.01 1.00E00 1.00E00 mRNA 3'-splice site recognition (GO:0000389) 6 0 .00 - < 0.01 1.00E00 1.00E00 spliceosome conformational change to release U4 (or U4atac) and U1 (or U11) (GO:0000388) 1 0 .00 - < 0.01 1.00E00 1.00E00 spliceosomal snRNP assembly (GO:0000387) 40 0 .01 - < 0.01 1.00E00 1.00E00 vesicle-mediated transport in synapse (GO:0099003) 166 0 .05 - < 0.01 1.00E00 1.00E00 regulation of alternative mRNA splicing, via spliceosome (GO:0000381) 58 0 .02 - < 0.01 1.00E00 1.00E00 alternative mRNA splicing, via spliceosome (GO:0000380) 25 0 .01 - < 0.01 1.00E00 1.00E00 tRNA-type intron splice site recognition and cleavage (GO:0000379) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) 245 0 .07 - < 0.01 1.00E00 1.00E00 RNA splicing, via transesterification reactions (GO:0000375) 249 0 .07 - < 0.01 1.00E00 1.00E00 parathyroid hormone secretion (GO:0035898) 2 0 .00 - < 0.01 1.00E00 1.00E00 exit from host cell (GO:0035891) 29 0 .01 - < 0.01 1.00E00 1.00E00 cis assembly of pre-catalytic spliceosome (GO:0000354) 2 0 .00 - < 0.01 1.00E00 1.00E00 generation of catalytic spliceosome for second transesterification step (GO:0000350) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein homodimerization activity (GO:0043496) 1 0 .00 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle cell differentiation (GO:0035886) 18 0 .01 - < 0.01 1.00E00 1.00E00 enteroendocrine cell differentiation (GO:0035883) 29 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylinositol 3-kinase/protein kinase B signal transduction (GO:0043491) 72 0 .02 - < 0.01 1.00E00 1.00E00 amacrine cell differentiation (GO:0035881) 9 0 .00 - < 0.01 1.00E00 1.00E00 malate-aspartate shuttle (GO:0043490) 9 0 .00 - < 0.01 1.00E00 1.00E00 embryonic nail plate morphogenesis (GO:0035880) 4 0 .00 - < 0.01 1.00E00 1.00E00 generation of catalytic spliceosome for first transesterification step (GO:0000349) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to flavonoid (GO:1905396) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to flavonoid (GO:1905395) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of binding (GO:0051099) 95 0 .03 - < 0.01 1.00E00 1.00E00 learned vocalization behavior or vocal learning (GO:0098598) 11 0 .00 - < 0.01 1.00E00 1.00E00 RNA stabilization (GO:0043489) 78 0 .02 - < 0.01 1.00E00 1.00E00 regulation of binding (GO:0051098) 194 0 .06 - < 0.01 1.00E00 1.00E00 observational learning (GO:0098597) 8 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane lactate transport (GO:0035879) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability (GO:0043488) 170 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of helicase activity (GO:0051097) 2 0 .00 - < 0.01 1.00E00 1.00E00 imitative learning (GO:0098596) 7 0 .00 - < 0.01 1.00E00 1.00E00 nail development (GO:0035878) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of RNA stability (GO:0043487) 183 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of helicase activity (GO:0051096) 5 0 .00 - < 0.01 1.00E00 1.00E00 endosome to pigment granule transport (GO:0043485) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of developmental process (GO:0051094) 1329 0 .39 - < 0.01 1.00E00 1.00E00 regulation of RNA splicing (GO:0043484) 187 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of developmental process (GO:0051093) 924 0 .27 - < 0.01 1.00E00 1.00E00 positive regulation of NF-kappaB transcription factor activity (GO:0051092) 106 0 .03 - < 0.01 1.00E00 1.00E00 lactate transmembrane transport (GO:0035873) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular pigment accumulation (GO:0043482) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-binding transcription factor activity (GO:0051091) 176 0 .05 - < 0.01 1.00E00 1.00E00 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway (GO:0035872) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA-binding transcription factor activity (GO:0051090) 297 0 .09 - < 0.01 1.00E00 1.00E00 protein K11-linked deubiquitination (GO:0035871) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein deneddylation (GO:0000338) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to presynapse (GO:1905386) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to presynapse (GO:1905384) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to presynapse (GO:1905383) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of snRNA transcription by RNA polymerase II (GO:1905382) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of snRNA transcription by RNA polymerase II (GO:1905381) 1 0 .00 - < 0.01 1.00E00 1.00E00 constitutive protein ectodomain proteolysis (GO:0051089) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of snRNA transcription by RNA polymerase II (GO:1905380) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to virus (GO:0098586) 80 0 .02 - < 0.01 1.00E00 1.00E00 chaperone mediated protein folding independent of cofactor (GO:0051086) 8 0 .00 - < 0.01 1.00E00 1.00E00 pigment accumulation (GO:0043476) 12 0 .00 - < 0.01 1.00E00 1.00E00 chaperone cofactor-dependent protein refolding (GO:0051085) 32 0 .01 - < 0.01 1.00E00 1.00E00 'de novo' post-translational protein folding (GO:0051084) 43 0 .01 - < 0.01 1.00E00 1.00E00 learned vocalization behavior (GO:0098583) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to potassium ion (GO:0035865) 15 0 .00 - < 0.01 1.00E00 1.00E00 pigment metabolic process involved in pigmentation (GO:0043474) 4 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' cotranslational protein folding (GO:0051083) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to potassium ion (GO:0035864) 21 0 .01 - < 0.01 1.00E00 1.00E00 pigmentation (GO:0043473) 105 0 .03 - < 0.01 1.00E00 1.00E00 detection of external biotic stimulus (GO:0098581) 26 0 .01 - < 0.01 1.00E00 1.00E00 dITP catabolic process (GO:0035863) 1 0 .00 - < 0.01 1.00E00 1.00E00 nuclear membrane disassembly (GO:0051081) 12 0 .00 - < 0.01 1.00E00 1.00E00 dITP metabolic process (GO:0035862) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of carbohydrate catabolic process (GO:0043470) 65 0 .02 - < 0.01 1.00E00 1.00E00 glial cell-derived neurotrophic factor receptor signaling pathway (GO:0035860) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to homocysteine (GO:1905375) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to homocysteine (GO:1905374) 1 0 .00 - < 0.01 1.00E00 1.00E00 ceramide phosphoethanolamine biosynthetic process (GO:1905373) 2 0 .00 - < 0.01 1.00E00 1.00E00 ceramide phosphoethanolamine catabolic process (GO:1905372) 1 0 .00 - < 0.01 1.00E00 1.00E00 ceramide phosphoethanolamine metabolic process (GO:1905371) 3 0 .00 - < 0.01 1.00E00 1.00E00 re-entry into mitotic cell cycle (GO:0000320) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of generation of precursor metabolites and energy (GO:0043467) 135 0 .04 - < 0.01 1.00E00 1.00E00 regulation of fermentation (GO:0043465) 4 0 .00 - < 0.01 1.00E00 1.00E00 megakaryocyte development (GO:0035855) 23 0 .01 - < 0.01 1.00E00 1.00E00 eosinophil fate commitment (GO:0035854) 2 0 .00 - < 0.01 1.00E00 1.00E00 chromosome passenger complex localization to spindle midzone (GO:0035853) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ATP-dependent activity (GO:0043462) 52 0 .02 - < 0.01 1.00E00 1.00E00 proton-transporting ATP synthase complex assembly (GO:0043461) 8 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in kidney development (GO:0035850) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of intralumenal vesicle formation (GO:1905366) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intralumenal vesicle formation (GO:1905365) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endosomal vesicle fusion (GO:1905364) 1 0 .00 - < 0.01 1.00E00 1.00E00 nephric duct elongation (GO:0035849) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular respiration (GO:0043457) 46 0 .01 - < 0.01 1.00E00 1.00E00 dihydrobiopterin metabolic process (GO:0051066) 2 0 .00 - < 0.01 1.00E00 1.00E00 uterine epithelium development (GO:0035847) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pentose-phosphate shunt (GO:0043456) 6 0 .00 - < 0.01 1.00E00 1.00E00 oviduct epithelium development (GO:0035846) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of secondary metabolic process (GO:0043455) 16 0 .00 - < 0.01 1.00E00 1.00E00 photoreceptor cell outer segment organization (GO:0035845) 13 0 .00 - < 0.01 1.00E00 1.00E00 cloaca development (GO:0035844) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to meiotic spindle (GO:1905359) 1 0 .00 - < 0.01 1.00E00 1.00E00 spine apparatus assembly (GO:1905355) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to oxygen radical (GO:0000305) 22 0 .01 - < 0.01 1.00E00 1.00E00 response to singlet oxygen (GO:0000304) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to superoxide (GO:0000303) 21 0 .01 - < 0.01 1.00E00 1.00E00 response to reactive oxygen species (GO:0000302) 173 0 .05 - < 0.01 1.00E00 1.00E00 detection of virus (GO:0009597) 4 0 .00 - < 0.01 1.00E00 1.00E00 retrograde transport, vesicle recycling within Golgi (GO:0000301) 9 0 .00 - < 0.01 1.00E00 1.00E00 alkene metabolic process (GO:0043449) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of small GTPase mediated signal transduction (GO:0051058) 64 0 .02 - < 0.01 1.00E00 1.00E00 detection of biotic stimulus (GO:0009595) 39 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of small GTPase mediated signal transduction (GO:0051057) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of small GTPase mediated signal transduction (GO:0051056) 303 0 .09 - < 0.01 1.00E00 1.00E00 detection of chemical stimulus (GO:0009593) 523 0 .15 - < 0.01 1.00E00 1.00E00 negative regulation of lipid biosynthetic process (GO:0051055) 57 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of DNA metabolic process (GO:0051054) 292 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of DNA metabolic process (GO:0051053) 135 0 .04 - < 0.01 1.00E00 1.00E00 detection of gravity (GO:0009590) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA metabolic process (GO:0051052) 500 0 .15 - < 0.01 1.00E00 1.00E00 negative regulation of transport (GO:0051051) 410 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of transport (GO:0051050) 858 1 .25 + 4.00 2.26E-01 1.00E00 ciliary transition zone assembly (GO:1905349) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cleavage furrow (GO:1905345) 2 0 .00 - < 0.01 1.00E00 1.00E00 prostaglandin catabolic process (GO:1905344) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of UV (GO:0009589) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to kinetochore (GO:1905342) 2 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-methionine acetylation (GO:0017196) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transport (GO:0051049) 1608 1 .47 + 2.13 3.86E-01 1.00E00 regulation of protein localization to kinetochore (GO:1905340) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of secretion (GO:0051048) 166 0 .05 - < 0.01 1.00E00 1.00E00 acetoacetic acid metabolic process (GO:0043438) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secretion (GO:0051047) 322 1 .09 + 10.65 9.03E-02 1.00E00 detection of visible light (GO:0009584) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of secretion (GO:0051046) 620 1 .18 + 5.53 1.68E-01 1.00E00 detection of light stimulus (GO:0009583) 63 0 .02 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-glutamine acetylation (GO:0017192) 1 0 .00 - < 0.01 1.00E00 1.00E00 oxoacid metabolic process (GO:0043436) 785 0 .23 - < 0.01 1.00E00 1.00E00 negative regulation of membrane protein ectodomain proteolysis (GO:0051045) 8 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein complex location (GO:0098544) 2 0 .00 - < 0.01 1.00E00 1.00E00 detection of abiotic stimulus (GO:0009582) 144 0 .04 - < 0.01 1.00E00 1.00E00 response to corticotropin-releasing hormone (GO:0043435) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of membrane protein ectodomain proteolysis (GO:0051044) 17 0 .00 - < 0.01 1.00E00 1.00E00 detection of other organism (GO:0098543) 19 0 .01 - < 0.01 1.00E00 1.00E00 detection of external stimulus (GO:0009581) 142 0 .04 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-aspartic acid acetylation (GO:0017190) 2 0 .00 - < 0.01 1.00E00 1.00E00 homologous recombination (GO:0035825) 67 0 .02 - < 0.01 1.00E00 1.00E00 response to peptide hormone (GO:0043434) 428 0 .12 - < 0.01 1.00E00 1.00E00 regulation of membrane protein ectodomain proteolysis (GO:0051043) 28 0 .01 - < 0.01 1.00E00 1.00E00 defense response to other organism (GO:0098542) 1061 0 .31 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-binding transcription factor activity (GO:0043433) 122 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of calcium-independent cell-cell adhesion (GO:0051042) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-independent cell-cell adhesion (GO:0051041) 1 0 .00 - < 0.01 1.00E00 1.00E00 gene conversion (GO:0035822) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium-independent cell-cell adhesion (GO:0051040) 2 0 .00 - < 0.01 1.00E00 1.00E00 modulation of process of another organism (GO:0035821) 116 0 .03 - < 0.01 1.00E00 1.00E00 nuclear membrane reassembly (GO:0031468) 26 0 .01 - < 0.01 1.00E00 1.00E00 glycine betaine transport (GO:0031460) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aggrephagy (GO:1905337) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of aggrephagy (GO:1905336) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aggrephagy (GO:1905335) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gastric motility (GO:1905333) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of morphogenesis of an epithelium (GO:1905332) 37 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-glutamic acid carboxylation (GO:0017187) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of morphogenesis of an epithelium (GO:1905331) 8 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase (GO:0017186) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of morphogenesis of an epithelium (GO:1905330) 66 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-lysine hydroxylation (GO:0017185) 10 0 .00 - < 0.01 1.00E00 1.00E00 protein histidyl modification to diphthamide (GO:0017183) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endosome size (GO:0051036) 11 0 .00 - < 0.01 1.00E00 1.00E00 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation (GO:0098535) 5 0 .00 - < 0.01 1.00E00 1.00E00 centriole assembly (GO:0098534) 33 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of renal sodium excretion (GO:0035815) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of renal sodium excretion (GO:0035814) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renal sodium excretion (GO:0035813) 8 0 .00 - < 0.01 1.00E00 1.00E00 tRNA transport (GO:0051031) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of strand invasion (GO:0098530) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal sodium excretion (GO:0035812) 4 0 .00 - < 0.01 1.00E00 1.00E00 snRNA transport (GO:0051030) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of urine volume (GO:0035811) 5 0 .00 - < 0.01 1.00E00 1.00E00 anthranilate metabolic process (GO:0043420) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of urine volume (GO:0035810) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycine betaine biosynthetic process (GO:0031456) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycine betaine metabolic process (GO:0031455) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heterochromatin formation (GO:0031453) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heterochromatin formation (GO:0031452) 6 0 .00 - < 0.01 1.00E00 1.00E00 tracheoesophageal septum formation (GO:1905327) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of meiosis I spindle assembly checkpoint (GO:1905326) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of meiosis I spindle assembly checkpoint (GO:1905325) 2 0 .00 - < 0.01 1.00E00 1.00E00 telomere-telomerase complex assembly (GO:1905324) 1 0 .00 - < 0.01 1.00E00 1.00E00 telomerase holoenzyme complex assembly (GO:1905323) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mesenchymal stem cell migration (GO:1905322) 4 0 .00 - < 0.01 1.00E00 1.00E00 neuromuscular junction development, skeletal muscle fiber (GO:0098529) 1 0 .00 - < 0.01 1.00E00 1.00E00 rRNA transport (GO:0051029) 3 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle fiber differentiation (GO:0098528) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal stem cell migration (GO:1905320) 4 0 .00 - < 0.01 1.00E00 1.00E00 fertilization (GO:0009566) 211 0 .06 - < 0.01 1.00E00 1.00E00 mRNA transport (GO:0051028) 135 0 .04 - < 0.01 1.00E00 1.00E00 regulation of urine volume (GO:0035809) 22 0 .01 - < 0.01 1.00E00 1.00E00 homocysteine catabolic process (GO:0043418) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle tissue regeneration (GO:0043417) 1 0 .00 - < 0.01 1.00E00 1.00E00 chiasma assembly (GO:0051026) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle tissue regeneration (GO:0043416) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle tissue regeneration (GO:0043415) 5 0 .00 - < 0.01 1.00E00 1.00E00 macromolecule methylation (GO:0043414) 125 0 .04 - < 0.01 1.00E00 1.00E00 macromolecule glycosylation (GO:0043413) 215 0 .06 - < 0.01 1.00E00 1.00E00 egg coat formation (GO:0035803) 2 0 .00 - < 0.01 1.00E00 1.00E00 macromolecule modification (GO:0043412) 1979 0 .58 - < 0.01 1.00E00 1.00E00 adrenal cortex formation (GO:0035802) 2 0 .00 - < 0.01 1.00E00 1.00E00 adrenal cortex development (GO:0035801) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of MAPK cascade (GO:0043410) 458 0 .13 - < 0.01 1.00E00 1.00E00 regulation of slow-twitch skeletal muscle fiber contraction (GO:0031449) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fast-twitch skeletal muscle fiber contraction (GO:0031448) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fast-twitch skeletal muscle fiber contraction (GO:0031446) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heterochromatin formation (GO:0031445) 9 0 .00 - < 0.01 1.00E00 1.00E00 slow-twitch skeletal muscle fiber contraction (GO:0031444) 1 0 .00 - < 0.01 1.00E00 1.00E00 fast-twitch skeletal muscle fiber contraction (GO:0031443) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA 3'-end processing (GO:0031442) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA 3'-end processing (GO:0031441) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA 3'-end processing (GO:0031440) 9 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal stem cell migration (GO:1905319) 1 0 .00 - < 0.01 1.00E00 1.00E00 inferior endocardial cushion morphogenesis (GO:1905317) 1 0 .00 - < 0.01 1.00E00 1.00E00 semi-lunar valve development (GO:1905314) 49 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:1905312) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:1905310) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of MAPK cascade (GO:0043409) 159 0 .05 - < 0.01 1.00E00 1.00E00 regulation of MAPK cascade (GO:0043408) 646 0 .19 - < 0.01 1.00E00 1.00E00 actin filament bundle assembly (GO:0051017) 63 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of MAP kinase activity (GO:0043407) 32 0 .01 - < 0.01 1.00E00 1.00E00 barbed-end actin filament capping (GO:0051016) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of MAP kinase activity (GO:0043406) 65 0 .02 - < 0.01 1.00E00 1.00E00 regulation of MAP kinase activity (GO:0043405) 101 0 .03 - < 0.01 1.00E00 1.00E00 actin filament severing (GO:0051014) 15 0 .00 - < 0.01 1.00E00 1.00E00 microtubule severing (GO:0051013) 9 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle tissue regeneration (GO:0043403) 38 0 .01 - < 0.01 1.00E00 1.00E00 microtubule sliding (GO:0051012) 3 0 .00 - < 0.01 1.00E00 1.00E00 steroid hormone receptor signaling pathway (GO:0043401) 81 0 .02 - < 0.01 1.00E00 1.00E00 cortisol secretion (GO:0043400) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac myofibril assembly (GO:1905305) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac myofibril assembly (GO:1905304) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macropinocytosis (GO:1905303) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion-dependent exocytosis (GO:0017158) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of macropinocytosis (GO:1905302) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of exocytosis (GO:0017157) 186 0 .05 - < 0.01 1.00E00 1.00E00 regulation of macropinocytosis (GO:1905301) 3 0 .00 - < 0.01 1.00E00 1.00E00 calcium-ion regulated exocytosis (GO:0017156) 38 0 .01 - < 0.01 1.00E00 1.00E00 endothelial to hematopoietic transition (GO:0098508) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal epithelial cell development (GO:1905300) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein lipase activity (GO:0051006) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein lipase activity (GO:0051005) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nitric-oxide synthase activity (GO:0051001) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nitric-oxide synthase activity (GO:0051000) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to methotrexate (GO:0031427) 1 0 .00 - < 0.01 1.00E00 1.00E00 keratinization (GO:0031424) 82 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of translation (GO:0017148) 131 0 .04 - < 0.01 1.00E00 1.00E00 stem cell division (GO:0017145) 22 0 .01 - < 0.01 1.00E00 1.00E00 insecticide metabolic process (GO:0017143) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to chromosome (GO:0070199) 16 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to chromosome, telomeric region (GO:0070198) 17 0 .00 - < 0.01 1.00E00 1.00E00 meiotic attachment of telomere to nuclear envelope (GO:0070197) 5 0 .00 - < 0.01 1.00E00 1.00E00 synaptonemal complex disassembly (GO:0070194) 2 0 .00 - < 0.01 1.00E00 1.00E00 synaptonemal complex organization (GO:0070193) 27 0 .01 - < 0.01 1.00E00 1.00E00 chromosome organization involved in meiotic cell cycle (GO:0070192) 65 0 .02 - < 0.01 1.00E00 1.00E00 oxylipin biosynthetic process (GO:0031408) 2 0 .00 - < 0.01 1.00E00 1.00E00 oxylipin metabolic process (GO:0031407) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein modification process (GO:0031401) 458 0 .13 - < 0.01 1.00E00 1.00E00 negative regulation of protein modification process (GO:0031400) 255 0 .07 - < 0.01 1.00E00 1.00E00 kynurenine metabolic process (GO:0070189) 10 0 .00 - < 0.01 1.00E00 1.00E00 nucleologenesis (GO:0017126) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tyrosyl-tRNA aminoacylation (GO:0070184) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tryptophanyl-tRNA aminoacylation (GO:0070183) 1 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane phospholipid scrambling (GO:0017121) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of Golgi to plasma membrane protein transport (GO:0042998) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Golgi to plasma membrane protein transport (GO:0042997) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Golgi to plasma membrane protein transport (GO:0042996) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of isotype switching to IgA isotypes (GO:0048298) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of isotype switching to IgA isotypes (GO:0048296) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of isotype switching to IgE isotypes (GO:0048295) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of isotype switching to IgE isotypes (GO:0048294) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of isotype switching to IgE isotypes (GO:0048293) 7 0 .00 - < 0.01 1.00E00 1.00E00 isotype switching to IgG isotypes (GO:0048291) 1 0 .00 - < 0.01 1.00E00 1.00E00 isotype switching to IgA isotypes (GO:0048290) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-serine biosynthetic process (GO:0070179) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-serine metabolic process (GO:0070178) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell proliferation (GO:1904899) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of enamel mineralization (GO:0070175) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell proliferation (GO:1904897) 2 0 .00 - < 0.01 1.00E00 1.00E00 ESCRT complex disassembly (GO:1904896) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of enamel mineralization (GO:0070173) 8 0 .00 - < 0.01 1.00E00 1.00E00 ESCRT complex assembly (GO:1904895) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tooth mineralization (GO:0070172) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor signaling pathway via STAT (GO:1904894) 48 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of tooth mineralization (GO:0070171) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor signaling pathway via STAT (GO:1904893) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of tooth mineralization (GO:0070170) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor signaling pathway via STAT (GO:1904892) 82 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of excitatory synapse assembly (GO:1904891) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of excitatory synapse assembly (GO:1904890) 2 0 .00 - < 0.01 1.00E00 1.00E00 amyloid precursor protein catabolic process (GO:0042987) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amyloid precursor protein biosynthetic process (GO:0042986) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid precursor protein biosynthetic process (GO:0042985) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amyloid precursor protein biosynthetic process (GO:0042984) 14 0 .00 - < 0.01 1.00E00 1.00E00 amyloid precursor protein biosynthetic process (GO:0042983) 1 0 .00 - < 0.01 1.00E00 1.00E00 isotype switching to IgE isotypes (GO:0048289) 3 0 .00 - < 0.01 1.00E00 1.00E00 amyloid precursor protein metabolic process (GO:0042982) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process (GO:0042981) 1479 0 .43 - < 0.01 1.00E00 1.00E00 lung alveolus development (GO:0048286) 54 0 .02 - < 0.01 1.00E00 1.00E00 organelle fission (GO:0048285) 348 0 .10 - < 0.01 1.00E00 1.00E00 organelle fusion (GO:0048284) 132 0 .04 - < 0.01 1.00E00 1.00E00 vesicle fusion with Golgi apparatus (GO:0048280) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of biomineral tissue development (GO:0070169) 54 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of biomineral tissue development (GO:0070168) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of biomineral tissue development (GO:0070167) 101 0 .03 - < 0.01 1.00E00 1.00E00 regulation of excitatory synapse assembly (GO:1904889) 22 0 .01 - < 0.01 1.00E00 1.00E00 enamel mineralization (GO:0070166) 15 0 .00 - < 0.01 1.00E00 1.00E00 cranial skeletal system development (GO:1904888) 75 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of adiponectin secretion (GO:0070165) 3 0 .00 - < 0.01 1.00E00 1.00E00 Wnt signalosome assembly (GO:1904887) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adiponectin secretion (GO:0070164) 4 0 .00 - < 0.01 1.00E00 1.00E00 beta-catenin destruction complex disassembly (GO:1904886) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adiponectin secretion (GO:0070163) 7 0 .00 - < 0.01 1.00E00 1.00E00 beta-catenin destruction complex assembly (GO:1904885) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase catalytic core complex assembly (GO:1904884) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomerase catalytic core complex assembly (GO:1904882) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hydrogen sulfide (GO:1904881) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to hydrogen sulfide (GO:1904880) 4 0 .00 - < 0.01 1.00E00 1.00E00 activation of Janus kinase activity (GO:0042976) 4 0 .00 - < 0.01 1.00E00 1.00E00 vesicle docking (GO:0048278) 59 0 .02 - < 0.01 1.00E00 1.00E00 mitochondrial threonyl-tRNA aminoacylation (GO:0070159) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial seryl-tRNA aminoacylation (GO:0070158) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1904879) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel (GO:1904878) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomerase RNA localization to Cajal body (GO:1904874) 9 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial glycyl-tRNA aminoacylation (GO:0070150) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomerase RNA localization to Cajal body (GO:1904872) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to Cajal body (GO:1904871) 10 0 .00 - < 0.01 1.00E00 1.00E00 clathrin coat assembly (GO:0048268) 19 0 .01 - < 0.01 1.00E00 1.00E00 behavioral response to pain (GO:0048266) 20 0 .01 - < 0.01 1.00E00 1.00E00 response to pain (GO:0048265) 37 0 .01 - < 0.01 1.00E00 1.00E00 determination of ventral identity (GO:0048264) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of centriole-centriole cohesion (GO:0030997) 3 0 .00 - < 0.01 1.00E00 1.00E00 determination of dorsal identity (GO:0048263) 5 0 .00 - < 0.01 1.00E00 1.00E00 determination of dorsal/ventral asymmetry (GO:0048262) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor-mediated endocytosis (GO:0048261) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of receptor-mediated endocytosis (GO:0048260) 56 0 .02 - < 0.01 1.00E00 1.00E00 recombinational interstrand cross-link repair (GO:0036298) 2 0 .00 - < 0.01 1.00E00 1.00E00 interstrand cross-link repair (GO:0036297) 42 0 .01 - < 0.01 1.00E00 1.00E00 response to increased oxygen levels (GO:0036296) 27 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to increased oxygen levels (GO:0036295) 12 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to decreased oxygen levels (GO:0036294) 137 0 .04 - < 0.01 1.00E00 1.00E00 regulation of protein localization to Cajal body (GO:1904869) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to decreased oxygen levels (GO:0036293) 306 0 .09 - < 0.01 1.00E00 1.00E00 mitochondrial asparaginyl-tRNA aminoacylation (GO:0070145) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to Cajal body (GO:1904867) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein trans-autophosphorylation (GO:0036290) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial alanyl-tRNA aminoacylation (GO:0070143) 1 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding (GO:0070142) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of beta-catenin-TCF complex assembly (GO:1904864) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to UV-A (GO:0070141) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of beta-catenin-TCF complex assembly (GO:1904863) 2 0 .00 - < 0.01 1.00E00 1.00E00 inhibitory synapse assembly (GO:1904862) 25 0 .01 - < 0.01 1.00E00 1.00E00 excitatory synapse assembly (GO:1904861) 22 0 .01 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in mitotic DNA replication (GO:1904860) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein transport (GO:0042953) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of receptor-mediated endocytosis (GO:0048259) 122 0 .04 - < 0.01 1.00E00 1.00E00 mRNA stabilization (GO:0048255) 68 0 .02 - < 0.01 1.00E00 1.00E00 snoRNA localization (GO:0048254) 5 0 .00 - < 0.01 1.00E00 1.00E00 lauric acid metabolic process (GO:0048252) 3 0 .00 - < 0.01 1.00E00 1.00E00 elastic fiber assembly (GO:0048251) 11 0 .00 - < 0.01 1.00E00 1.00E00 iron import into the mitochondrion (GO:0048250) 2 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-serine autophosphorylation (GO:0036289) 9 0 .00 - < 0.01 1.00E00 1.00E00 SAGA complex assembly (GO:0036285) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial translation (GO:0070131) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial translation (GO:0070130) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of protein localization to telomere (GO:1904851) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of protein localization to telomere (GO:1904850) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucoside transport (GO:0042946) 3 0 .00 - < 0.01 1.00E00 1.00E00 D-serine transmembrane transport (GO:0042942) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-alanine transmembrane transport (GO:0042941) 1 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte chemotaxis (GO:0048247) 27 0 .01 - < 0.01 1.00E00 1.00E00 D-amino acid transport (GO:0042940) 6 0 .00 - < 0.01 1.00E00 1.00E00 macrophage chemotaxis (GO:0048246) 16 0 .00 - < 0.01 1.00E00 1.00E00 eosinophil chemotaxis (GO:0048245) 20 0 .01 - < 0.01 1.00E00 1.00E00 norepinephrine secretion (GO:0048243) 1 0 .00 - < 0.01 1.00E00 1.00E00 epinephrine secretion (GO:0048242) 1 0 .00 - < 0.01 1.00E00 1.00E00 epinephrine transport (GO:0048241) 5 0 .00 - < 0.01 1.00E00 1.00E00 thiamine pyrophosphate transmembrane transport (GO:0030974) 2 0 .00 - < 0.01 1.00E00 1.00E00 sperm capacitation (GO:0048240) 28 0 .01 - < 0.01 1.00E00 1.00E00 retrograde protein transport, ER to cytosol (GO:0030970) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial translation (GO:0070129) 26 0 .01 - < 0.01 1.00E00 1.00E00 tRNA aminoacylation for mitochondrial protein translation (GO:0070127) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell chemotaxis to fibroblast growth factor (GO:1904849) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial translational termination (GO:0070126) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell chemotaxis to fibroblast growth factor (GO:1904848) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial translational elongation (GO:0070125) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell chemotaxis to fibroblast growth factor (GO:1904847) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial translational initiation (GO:0070124) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to L-glutamine (GO:1904845) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to L-glutamine (GO:1904844) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to nitroglycerin (GO:1904843) 1 0 .00 - < 0.01 1.00E00 1.00E00 ciliary neurotrophic factor-mediated signaling pathway (GO:0070120) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to nitroglycerin (GO:1904842) 2 0 .00 - < 0.01 1.00E00 1.00E00 tripeptide transport (GO:0042939) 12 0 .00 - < 0.01 1.00E00 1.00E00 dipeptide transport (GO:0042938) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA recombination at telomere (GO:0048239) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of diacylglycerol biosynthetic process (GO:1900480) 1 0 .00 - < 0.01 1.00E00 1.00E00 enterobactin transport (GO:0042930) 1 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum unfolded protein response (GO:0030968) 59 0 .02 - < 0.01 1.00E00 1.00E00 male gamete generation (GO:0048232) 674 0 .20 - < 0.01 1.00E00 1.00E00 swimming behavior (GO:0036269) 2 0 .00 - < 0.01 1.00E00 1.00E00 swimming (GO:0036268) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-arginine hydroxylation (GO:0030961) 1 0 .00 - < 0.01 1.00E00 1.00E00 RNA (guanine-N7)-methylation (GO:0036265) 7 0 .00 - < 0.01 1.00E00 1.00E00 beta-catenin-TCF complex assembly (GO:1904837) 1 0 .00 - < 0.01 1.00E00 1.00E00 7-methylguanosine cap hypermethylation (GO:0036261) 8 0 .00 - < 0.01 1.00E00 1.00E00 dorsal root ganglion morphogenesis (GO:1904835) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA capping (GO:0036260) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aortic smooth muscle cell differentiation (GO:1904831) 2 0 .00 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated glucocorticoid signaling pathway (GO:0042921) 5 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane to endosome transport (GO:0048227) 9 0 .00 - < 0.01 1.00E00 1.00E00 astral microtubule nucleation (GO:0030954) 1 0 .00 - < 0.01 1.00E00 1.00E00 astral microtubule organization (GO:0030953) 11 0 .00 - < 0.01 1.00E00 1.00E00 establishment or maintenance of cytoskeleton polarity (GO:0030952) 7 0 .00 - < 0.01 1.00E00 1.00E00 multivesicular body assembly (GO:0036258) 32 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of microtubule cytoskeleton polarity (GO:0030951) 4 0 .00 - < 0.01 1.00E00 1.00E00 multivesicular body organization (GO:0036257) 33 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of actin cytoskeleton polarity (GO:0030950) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to methylamine (GO:0036255) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aortic smooth muscle cell differentiation (GO:1904829) 2 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-27-mediated signaling pathway (GO:0070106) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen sulfide biosynthetic process (GO:1904828) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-6-mediated signaling pathway (GO:0070105) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-6-mediated signaling pathway (GO:0070104) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hydrogen sulfide biosynthetic process (GO:1904826) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-6-mediated signaling pathway (GO:0070103) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to microtubule plus-end (GO:1904825) 3 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome transport along microtubule (GO:0036250) 1 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-6-mediated signaling pathway (GO:0070102) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine-mediated signaling pathway (GO:0070101) 3 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase transmembrane transport (GO:1904823) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine-mediated signaling pathway (GO:0070100) 7 0 .00 - < 0.01 1.00E00 1.00E00 alkanesulfonate transmembrane transport (GO:0042918) 8 0 .00 - < 0.01 1.00E00 1.00E00 inter-Golgi cisterna vesicle-mediated transport (GO:0048219) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030949) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030947) 32 0 .01 - < 0.01 1.00E00 1.00E00 Golgi vesicle docking (GO:0048211) 1 0 .00 - < 0.01 1.00E00 1.00E00 Golgi vesicle fusion to target membrane (GO:0048210) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to chromosome, telomeric region (GO:1904816) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to chromosome, telomeric region (GO:1904815) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to chromosome, telomeric region (GO:1904814) 10 0 .00 - < 0.01 1.00E00 1.00E00 rRNA acetylation involved in maturation of SSU-rRNA (GO:1904812) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dense core granule transport (GO:1904811) 3 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic transport (GO:0042908) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of long-term synaptic depression (GO:1900454) 7 0 .00 - < 0.01 1.00E00 1.00E00 9-cis-retinoic acid metabolic process (GO:0042905) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of long-term synaptic depression (GO:1900453) 3 0 .00 - < 0.01 1.00E00 1.00E00 9-cis-retinoic acid biosynthetic process (GO:0042904) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of long-term synaptic depression (GO:1900452) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate receptor signaling pathway (GO:1900451) 5 0 .00 - < 0.01 1.00E00 1.00E00 COPII vesicle coating (GO:0048208) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glutamate receptor signaling pathway (GO:1900450) 2 0 .00 - < 0.01 1.00E00 1.00E00 vesicle targeting, rough ER to cis-Golgi (GO:0048207) 23 0 .01 - < 0.01 1.00E00 1.00E00 COPI coating of Golgi vesicle (GO:0048205) 6 0 .00 - < 0.01 1.00E00 1.00E00 vesicle targeting, trans-Golgi to endosome (GO:0048203) 2 0 .00 - < 0.01 1.00E00 1.00E00 Golgi transport vesicle coating (GO:0048200) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dense core granule transport (GO:1904809) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein oxidation (GO:1904808) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein oxidation (GO:1904806) 2 0 .00 - < 0.01 1.00E00 1.00E00 granulocyte activation (GO:0036230) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of translation involved in cellular response to UV (GO:1904803) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutamate receptor signaling pathway (GO:1900449) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron remodeling (GO:1904800) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to nuclear inner membrane (GO:0036228) 3 0 .00 - < 0.01 1.00E00 1.00E00 midbrain-hindbrain boundary development (GO:0030917) 7 0 .00 - < 0.01 1.00E00 1.00E00 otic vesicle formation (GO:0030916) 8 0 .00 - < 0.01 1.00E00 1.00E00 paranodal junction assembly (GO:0030913) 6 0 .00 - < 0.01 1.00E00 1.00E00 olfactory placode formation (GO:0030910) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to stem cell factor stimulus (GO:0036216) 51 0 .01 - < 0.01 1.00E00 1.00E00 response to stem cell factor (GO:0036215) 51 0 .01 - < 0.01 1.00E00 1.00E00 contractile ring contraction (GO:0036213) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein modification process (GO:0036211) 1781 0 .52 - < 0.01 1.00E00 1.00E00 positive regulation of defense response to bacterium (GO:1900426) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of defense response to bacterium (GO:1900425) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of defense response to bacterium (GO:1900424) 19 0 .01 - < 0.01 1.00E00 1.00E00 protein splicing (GO:0030908) 2 0 .00 - < 0.01 1.00E00 1.00E00 notochord development (GO:0030903) 17 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain development (GO:0030902) 158 0 .05 - < 0.01 1.00E00 1.00E00 midbrain development (GO:0030901) 90 0 .03 - < 0.01 1.00E00 1.00E00 forebrain development (GO:0030900) 417 0 .12 - < 0.01 1.00E00 1.00E00 spermine transport (GO:0000296) 3 0 .00 - < 0.01 1.00E00 1.00E00 RNA fragment catabolic process (GO:0000292) 1 0 .00 - < 0.01 1.00E00 1.00E00 deadenylation-dependent decapping of nuclear-transcribed mRNA (GO:0000290) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to oxidative stress (GO:1900409) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to oxidative stress (GO:1900408) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to oxidative stress (GO:1900407) 22 0 .01 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289) 20 0 .01 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) 36 0 .01 - < 0.01 1.00E00 1.00E00 mitotic cytokinesis (GO:0000281) 89 0 .03 - < 0.01 1.00E00 1.00E00 nuclear division (GO:0000280) 322 0 .09 - < 0.01 1.00E00 1.00E00 Rac protein signal transduction (GO:0016601) 26 0 .01 - < 0.01 1.00E00 1.00E00 mitotic cell cycle (GO:0000278) 592 0 .17 - < 0.01 1.00E00 1.00E00 polysaccharide catabolic process (GO:0000272) 23 0 .01 - < 0.01 1.00E00 1.00E00 polysaccharide biosynthetic process (GO:0000271) 34 0 .01 - < 0.01 1.00E00 1.00E00 peptidoglycan metabolic process (GO:0000270) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial fission (GO:0000266) 17 0 .00 - < 0.01 1.00E00 1.00E00 ureter maturation (GO:0035799) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial membrane permeability (GO:0035795) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial membrane permeability (GO:0035794) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway (GO:0035793) 3 0 .00 - < 0.01 1.00E00 1.00E00 platelet-derived growth factor receptor-beta signaling pathway (GO:0035791) 56 0 .02 - < 0.01 1.00E00 1.00E00 platelet-derived growth factor receptor-alpha signaling pathway (GO:0035790) 50 0 .01 - < 0.01 1.00E00 1.00E00 allantoin catabolic process (GO:0000256) 1 0 .00 - < 0.01 1.00E00 1.00E00 allantoin metabolic process (GO:0000255) 9 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in metanephros development (GO:0035788) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of corticotropin-releasing hormone secretion (GO:0043397) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in kidney development (GO:0035787) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein binding (GO:0043393) 97 0 .03 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell costimulation (GO:0035783) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA binding (GO:0043392) 28 0 .01 - < 0.01 1.00E00 1.00E00 mature natural killer cell chemotaxis (GO:0035782) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD86 biosynthetic process (GO:0035781) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD80 biosynthetic process (GO:0035780) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intestinal epithelial cell development (GO:1905298) 1 0 .00 - < 0.01 1.00E00 1.00E00 spliceosomal complex assembly (GO:0000245) 75 0 .02 - < 0.01 1.00E00 1.00E00 spliceosomal tri-snRNP complex assembly (GO:0000244) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CAMKK-AMPK signaling cascade (GO:1905291) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA binding (GO:0043388) 33 0 .01 - < 0.01 1.00E00 1.00E00 mycotoxin catabolic process (GO:0043387) 1 0 .00 - < 0.01 1.00E00 1.00E00 mycotoxin metabolic process (GO:0043385) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative T cell selection (GO:0043383) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0035774) 34 0 .01 - < 0.01 1.00E00 1.00E00 insulin secretion involved in cellular response to glucose stimulus (GO:0035773) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of memory T cell differentiation (GO:0043382) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of memory T cell differentiation (GO:0043381) 2 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-13-mediated signaling pathway (GO:0035772) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of memory T cell differentiation (GO:0043380) 12 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-4-mediated signaling pathway (GO:0035771) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CAMKK-AMPK signaling cascade (GO:1905289) 5 0 .00 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle cell apoptotic process (GO:1905288) 1 0 .00 - < 0.01 1.00E00 1.00E00 fibrous ring of heart morphogenesis (GO:1905285) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde transport, endosome to Golgi (GO:1905281) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of retrograde transport, endosome to Golgi (GO:1905280) 1 0 .00 - < 0.01 1.00E00 1.00E00 memory T cell differentiation (GO:0043379) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043378) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043377) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell chemotaxis to fibroblast growth factor (GO:0035768) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD8-positive, alpha-beta T cell differentiation (GO:0043376) 8 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell chemotaxis (GO:0035767) 10 0 .00 - < 0.01 1.00E00 1.00E00 cell chemotaxis to fibroblast growth factor (GO:0035766) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell lineage commitment (GO:0043375) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell differentiation (GO:0043374) 7 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell lineage commitment (GO:0043373) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) 62 0 .02 - < 0.01 1.00E00 1.00E00 regulation of retrograde transport, endosome to Golgi (GO:1905279) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial tube formation (GO:1905278) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial tube formation (GO:1905276) 9 0 .00 - < 0.01 1.00E00 1.00E00 microtubule cytoskeleton organization (GO:0000226) 580 0 .17 - < 0.01 1.00E00 1.00E00 regulation of modification of postsynaptic actin cytoskeleton (GO:1905274) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proton-transporting ATP synthase activity, rotational mechanism (GO:1905273) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) 22 0 .01 - < 0.01 1.00E00 1.00E00 positive T cell selection (GO:0043368) 35 0 .01 - < 0.01 1.00E00 1.00E00 mesangial cell-matrix adhesion (GO:0035759) 2 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell differentiation (GO:0043367) 61 0 .02 - < 0.01 1.00E00 1.00E00 beta selection (GO:0043366) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell chemotaxis (GO:0035754) 6 0 .00 - < 0.01 1.00E00 1.00E00 nucleate erythrocyte differentiation (GO:0043363) 1 0 .00 - < 0.01 1.00E00 1.00E00 lysosomal lumen pH elevation (GO:0035752) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lysosomal lumen pH (GO:0035751) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein modification process (GO:0031399) 759 0 .22 - < 0.01 1.00E00 1.00E00 protein localization to myelin sheath abaxonal region (GO:0035750) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein ubiquitination (GO:0031398) 108 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein ubiquitination (GO:0031397) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein ubiquitination (GO:0031396) 195 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin biosynthetic process (GO:0031394) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of prostaglandin biosynthetic process (GO:0031393) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of prostaglandin biosynthetic process (GO:0031392) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin organization (GO:1905269) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chromatin organization (GO:1905268) 9 0 .00 - < 0.01 1.00E00 1.00E00 meiotic spindle organization (GO:0000212) 22 0 .01 - < 0.01 1.00E00 1.00E00 natural killer cell chemotaxis (GO:0035747) 3 0 .00 - < 0.01 1.00E00 1.00E00 enucleate erythrocyte maturation (GO:0043354) 4 0 .00 - < 0.01 1.00E00 1.00E00 enucleate erythrocyte differentiation (GO:0043353) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway (GO:1905259) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway (GO:1905258) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein polyubiquitination (GO:0000209) 248 0 .07 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell proliferation (GO:0035739) 9 0 .00 - < 0.01 1.00E00 1.00E00 intraciliary transport involved in cilium assembly (GO:0035735) 7 0 .00 - < 0.01 1.00E00 1.00E00 hepatic stellate cell activation (GO:0035733) 2 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide storage (GO:0035732) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aspartic-type peptidase activity (GO:1905247) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of modification of synaptic structure (GO:1905244) 22 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to 3,3',5-triiodo-L-thyronine (GO:1905243) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to 3,3',5-triiodo-L-thyronine (GO:1905242) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hepatocyte growth factor stimulus (GO:0035729) 15 0 .00 - < 0.01 1.00E00 1.00E00 response to hepatocyte growth factor (GO:0035728) 17 0 .00 - < 0.01 1.00E00 1.00E00 common myeloid progenitor cell proliferation (GO:0035726) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein unfolding (GO:0043335) 5 0 .00 - < 0.01 1.00E00 1.00E00 sodium ion transmembrane transport (GO:0035725) 152 0 .04 - < 0.01 1.00E00 1.00E00 interleukin-15-mediated signaling pathway (GO:0035723) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to dsRNA (GO:0043331) 56 0 .02 - < 0.01 1.00E00 1.00E00 interleukin-12-mediated signaling pathway (GO:0035722) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to exogenous dsRNA (GO:0043330) 48 0 .01 - < 0.01 1.00E00 1.00E00 intraciliary retrograde transport (GO:0035721) 14 0 .00 - < 0.01 1.00E00 1.00E00 intraciliary anterograde transport (GO:0035720) 19 0 .01 - < 0.01 1.00E00 1.00E00 N-terminal protein amino acid modification (GO:0031365) 23 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to L-glutamate (GO:1905232) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to insecticide (GO:0017085) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043328) 16 0 .00 - < 0.01 1.00E00 1.00E00 pigment metabolic process involved in developmental pigmentation (GO:0043324) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell degranulation (GO:0043323) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to nitrogen dioxide (GO:0035713) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell degranulation (GO:0043322) 1 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 2 cell activation (GO:0035712) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell degranulation (GO:0043321) 5 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell degranulation (GO:0043320) 7 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 1 cell activation (GO:0035711) 3 0 .00 - < 0.01 1.00E00 1.00E00 CD4-positive, alpha-beta T cell activation (GO:0035710) 75 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to thyrotropin-releasing hormone (GO:1905229) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to thyrotropin-releasing hormone (GO:1905225) 2 0 .00 - < 0.01 1.00E00 1.00E00 epicardium morphogenesis (GO:1905223) 2 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular canal morphogenesis (GO:1905222) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of platelet formation (GO:1905221) 2 0 .00 - < 0.01 1.00E00 1.00E00 memory T cell activation (GO:0035709) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytotoxic T cell degranulation (GO:0043318) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytotoxic T cell degranulation (GO:0043317) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytotoxic T cell degranulation (GO:0043316) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neutrophil degranulation (GO:0043315) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neutrophil degranulation (GO:0043314) 2 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 17 cell chemotaxis (GO:0035705) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neutrophil degranulation (GO:0043313) 8 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil degranulation (GO:0043312) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eosinophil degranulation (GO:0043311) 2 0 .00 - < 0.01 1.00E00 1.00E00 monocyte homeostasis (GO:0035702) 3 0 .00 - < 0.01 1.00E00 1.00E00 hematopoietic stem cell migration (GO:0035701) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of eosinophil degranulation (GO:0043310) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of defense response (GO:0031349) 442 0 .13 - < 0.01 1.00E00 1.00E00 negative regulation of defense response (GO:0031348) 272 1 .08 + 12.61 7.67E-02 1.00E00 regulation of defense response (GO:0031347) 842 1 .25 + 4.07 2.22E-01 1.00E00 positive regulation of cell projection organization (GO:0031346) 353 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell projection organization (GO:0031345) 182 0 .05 - < 0.01 1.00E00 1.00E00 regulation of cell projection organization (GO:0031344) 654 0 .19 - < 0.01 1.00E00 1.00E00 positive regulation of cell killing (GO:0031343) 70 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of cell killing (GO:0031342) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell killing (GO:0031341) 109 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of vesicle fusion (GO:0031340) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of platelet formation (GO:1905219) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to astaxanthin (GO:1905217) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of RNA binding (GO:1905216) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RNA binding (GO:1905215) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic chromosome condensation (GO:1905213) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eosinophil degranulation (GO:0043309) 3 0 .00 - < 0.01 1.00E00 1.00E00 eosinophil degranulation (GO:0043308) 5 0 .00 - < 0.01 1.00E00 1.00E00 eosinophil activation (GO:0043307) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell degranulation (GO:0043306) 14 0 .00 - < 0.01 1.00E00 1.00E00 respiratory chain complex III assembly (GO:0017062) 13 0 .00 - < 0.01 1.00E00 1.00E00 7-methylguanosine RNA capping (GO:0009452) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell degranulation (GO:0043305) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell degranulation (GO:0043304) 28 0 .01 - < 0.01 1.00E00 1.00E00 RNA modification (GO:0009451) 170 0 .05 - < 0.01 1.00E00 1.00E00 mast cell degranulation (GO:0043303) 30 0 .01 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid catabolic process (GO:0009450) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte degranulation (GO:0043302) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte degranulation (GO:0043301) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukocyte degranulation (GO:0043300) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vesicle fusion (GO:0031339) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vesicle fusion (GO:0031338) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of sulfur amino acid metabolic process (GO:0031335) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein-containing complex assembly (GO:0031334) 206 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of protein-containing complex assembly (GO:0031333) 140 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of cardiocyte differentiation (GO:1905209) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiocyte differentiation (GO:1905208) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiocyte differentiation (GO:1905207) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of connective tissue replacement (GO:1905205) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue replacement (GO:1905204) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of connective tissue replacement (GO:1905203) 6 0 .00 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid biosynthetic process (GO:0009449) 6 0 .00 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid metabolic process (GO:0009448) 8 0 .00 - < 0.01 1.00E00 1.00E00 putrescine catabolic process (GO:0009447) 2 0 .00 - < 0.01 1.00E00 1.00E00 putrescine biosynthetic process (GO:0009446) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0017055) 2 0 .00 - < 0.01 1.00E00 1.00E00 putrescine metabolic process (GO:0009445) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyridoxal 5'-phosphate salvage (GO:0009443) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycolate metabolic process (GO:0009441) 3 0 .00 - < 0.01 1.00E00 1.00E00 cyanate catabolic process (GO:0009440) 2 0 .00 - < 0.01 1.00E00 1.00E00 cyanate metabolic process (GO:0009439) 2 0 .00 - < 0.01 1.00E00 1.00E00 methylglyoxal metabolic process (GO:0009438) 6 0 .00 - < 0.01 1.00E00 1.00E00 carnitine metabolic process (GO:0009437) 13 0 .00 - < 0.01 1.00E00 1.00E00 glyoxylate catabolic process (GO:0009436) 3 0 .00 - < 0.01 1.00E00 1.00E00 NAD biosynthetic process (GO:0009435) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of chemokine-mediated signaling pathway (GO:0070099) 10 0 .00 - < 0.01 1.00E00 1.00E00 chemokine-mediated signaling pathway (GO:0070098) 73 0 .02 - < 0.01 1.00E00 1.00E00 protein import (GO:0017038) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucagon secretion (GO:0070094) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glucagon secretion (GO:0070093) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucagon secretion (GO:0070092) 8 0 .00 - < 0.01 1.00E00 1.00E00 glucagon secretion (GO:0070091) 1 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent endocytosis (GO:0070086) 6 0 .00 - < 0.01 1.00E00 1.00E00 glycosylation (GO:0070085) 236 0 .07 - < 0.01 1.00E00 1.00E00 response to light stimulus (GO:0009416) 321 0 .09 - < 0.01 1.00E00 1.00E00 response to water (GO:0009415) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to water deprivation (GO:0009414) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to UV (GO:0009411) 155 0 .05 - < 0.01 1.00E00 1.00E00 response to xenobiotic stimulus (GO:0009410) 442 0 .13 - < 0.01 1.00E00 1.00E00 vesicle targeting, to, from or within Golgi (GO:0048199) 30 0 .01 - < 0.01 1.00E00 1.00E00 Golgi vesicle budding (GO:0048194) 10 0 .00 - < 0.01 1.00E00 1.00E00 Golgi vesicle transport (GO:0048193) 289 0 .08 - < 0.01 1.00E00 1.00E00 response to cold (GO:0009409) 44 0 .01 - < 0.01 1.00E00 1.00E00 response to heat (GO:0009408) 93 0 .03 - < 0.01 1.00E00 1.00E00 regulation of neuron remodeling (GO:1904799) 1 0 .00 - < 0.01 1.00E00 1.00E00 toxin catabolic process (GO:0009407) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of core promoter binding (GO:1904798) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transforming growth factor beta receptor signaling pathway (GO:0017015) 144 0 .04 - < 0.01 1.00E00 1.00E00 tear secretion (GO:0070075) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of core promoter binding (GO:1904797) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein nitrosylation (GO:0017014) 4 0 .00 - < 0.01 1.00E00 1.00E00 toxin metabolic process (GO:0009404) 18 0 .01 - < 0.01 1.00E00 1.00E00 vacuolar proton-transporting V-type ATPase complex assembly (GO:0070072) 6 0 .00 - < 0.01 1.00E00 1.00E00 toxin biosynthetic process (GO:0009403) 1 0 .00 - < 0.01 1.00E00 1.00E00 proton-transporting two-sector ATPase complex assembly (GO:0070071) 16 0 .00 - < 0.01 1.00E00 1.00E00 proton-transporting V-type ATPase complex assembly (GO:0070070) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of shelterin complex assembly (GO:1904792) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of shelterin complex assembly (GO:1904791) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of shelterin complex assembly (GO:1904790) 2 0 .00 - < 0.01 1.00E00 1.00E00 amide transport (GO:0042886) 146 0 .04 - < 0.01 1.00E00 1.00E00 cysteine transport (GO:0042883) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein-tetrapyrrole linkage (GO:0017006) 1 0 .00 - < 0.01 1.00E00 1.00E00 cytochrome complex assembly (GO:0017004) 43 0 .01 - < 0.01 1.00E00 1.00E00 protein-heme linkage (GO:0017003) 1 0 .00 - < 0.01 1.00E00 1.00E00 NLRP1 inflammasome complex assembly (GO:1904784) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of NMDA glutamate receptor activity (GO:1904783) 3 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' actin filament nucleation (GO:0070060) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to centrosome (GO:1904781) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to centrosome (GO:1904780) 2 0 .00 - < 0.01 1.00E00 1.00E00 D-glucuronate transmembrane transport (GO:0042874) 1 0 .00 - < 0.01 1.00E00 1.00E00 arachidonate secretion (GO:0050482) 25 0 .01 - < 0.01 1.00E00 1.00E00 aldonate transmembrane transport (GO:0042873) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of short-term neuronal synaptic plasticity (GO:0048174) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of short-term neuronal synaptic plasticity (GO:0048172) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of long-term neuronal synaptic plasticity (GO:0048170) 9 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to centrosome (GO:1904779) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cell cortex (GO:1904778) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cell cortex (GO:1904777) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell cortex (GO:1904776) 9 0 .00 - < 0.01 1.00E00 1.00E00 mRNA splicing, via endonucleolytic cleavage and ligation (GO:0070054) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquinone biosynthetic process (GO:1904775) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuron cellular homeostasis (GO:0070050) 65 0 .02 - < 0.01 1.00E00 1.00E00 response to tetrachloromethane (GO:1904772) 4 0 .00 - < 0.01 1.00E00 1.00E00 antisense RNA metabolic process (GO:0042868) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate catabolic process (GO:0042867) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate biosynthetic process (GO:0042866) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of long-term neuronal synaptic plasticity (GO:0048169) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of neuronal synaptic plasticity (GO:0048168) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of synaptic plasticity (GO:0048167) 208 0 .06 - < 0.01 1.00E00 1.00E00 fused antrum stage (GO:0048165) 6 0 .00 - < 0.01 1.00E00 1.00E00 multi-layer follicle stage (GO:0048162) 3 0 .00 - < 0.01 1.00E00 1.00E00 primary follicle stage (GO:0048160) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell proliferation (GO:0030890) 47 0 .01 - < 0.01 1.00E00 1.00E00 chaperone-mediated autophagy translocation complex disassembly (GO:1904764) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myofibroblast differentiation (GO:1904762) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myofibroblast differentiation (GO:1904761) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myofibroblast differentiation (GO:1904760) 6 0 .00 - < 0.01 1.00E00 1.00E00 L-alanine catabolic process (GO:0042853) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-alanine metabolic process (GO:0042851) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of B cell proliferation (GO:0030889) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell proliferation (GO:0030888) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid dendritic cell activation (GO:0030887) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid dendritic cell activation (GO:0030886) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myeloid dendritic cell activation (GO:0030885) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell migration (GO:1904754) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell migration (GO:1904753) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell migration (GO:1904752) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to nucleolus (GO:1904751) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to nucleolus (GO:1904750) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral response to ethanol (GO:0048149) 11 0 .00 - < 0.01 1.00E00 1.00E00 D-xylose catabolic process (GO:0042843) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral response to cocaine (GO:0048148) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast proliferation (GO:0048147) 34 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast proliferation (GO:0048146) 53 0 .02 - < 0.01 1.00E00 1.00E00 D-glucuronate catabolic process (GO:0042840) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast proliferation (GO:0048145) 88 0 .03 - < 0.01 1.00E00 1.00E00 mammary gland development (GO:0030879) 126 1 .04 + 27.22 3.62E-02 1.00E00 fibroblast proliferation (GO:0048144) 41 0 .01 - < 0.01 1.00E00 1.00E00 thyroid gland development (GO:0030878) 30 0 .01 - < 0.01 1.00E00 1.00E00 astrocyte activation (GO:0048143) 19 0 .01 - < 0.01 1.00E00 1.00E00 osteoclast maturation (GO:0036179) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to nucleolus (GO:1904749) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in development (GO:1904748) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process involved in development (GO:1904747) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in development (GO:1904746) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric DNA binding (GO:1904744) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric DNA binding (GO:1904743) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein arginylation (GO:0016598) 2 0 .00 - < 0.01 1.00E00 1.00E00 D-glucuronate metabolic process (GO:0042839) 5 0 .00 - < 0.01 1.00E00 1.00E00 defense response to protozoan (GO:0042832) 27 0 .01 - < 0.01 1.00E00 1.00E00 spermatocyte division (GO:0048137) 2 0 .00 - < 0.01 1.00E00 1.00E00 male germ-line stem cell asymmetric division (GO:0048133) 3 0 .00 - < 0.01 1.00E00 1.00E00 cortical actin cytoskeleton organization (GO:0030866) 40 0 .01 - < 0.01 1.00E00 1.00E00 cortical cytoskeleton organization (GO:0030865) 56 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of polarized epithelial cell differentiation (GO:0030862) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of polarized epithelial cell differentiation (GO:0030860) 2 0 .00 - < 0.01 1.00E00 1.00E00 phenotypic switching (GO:0036166) 1 0 .00 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle cell migration (GO:1904738) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase (GO:1904736) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase (GO:1904735) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal lipid absorption (GO:1904731) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intestinal lipid absorption (GO:1904730) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secondary metabolite biosynthetic process (GO:1900378) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of secondary metabolite biosynthetic process (GO:1900377) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of secondary metabolite biosynthetic process (GO:1900376) 16 0 .00 - < 0.01 1.00E00 1.00E00 amyloid-beta metabolic process (GO:0050435) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of viral transcription (GO:0050434) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of catecholamine secretion (GO:0050433) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of purine nucleotide biosynthetic process (GO:1900373) 13 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine secretion (GO:0050432) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of purine nucleotide biosynthetic process (GO:1900372) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyridoxal phosphate biosynthetic process (GO:0042823) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of purine nucleotide biosynthetic process (GO:1900371) 21 0 .01 - < 0.01 1.00E00 1.00E00 pyridoxal phosphate metabolic process (GO:0042822) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of post-transcriptional gene silencing by RNA (GO:1900370) 12 0 .00 - < 0.01 1.00E00 1.00E00 vitamin B6 catabolic process (GO:0042820) 1 0 .00 - < 0.01 1.00E00 1.00E00 polarized epithelial cell differentiation (GO:0030859) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell differentiation (GO:0030858) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell differentiation (GO:0030857) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell differentiation (GO:0030856) 159 0 .05 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation (GO:0030855) 649 0 .19 - < 0.01 1.00E00 1.00E00 positive regulation of granulocyte differentiation (GO:0030854) 8 0 .00 - < 0.01 1.00E00 1.00E00 inner dynein arm assembly (GO:0036159) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of granulocyte differentiation (GO:0030853) 10 0 .00 - < 0.01 1.00E00 1.00E00 outer dynein arm assembly (GO:0036158) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of granulocyte differentiation (GO:0030852) 16 0 .00 - < 0.01 1.00E00 1.00E00 granulocyte differentiation (GO:0030851) 27 0 .01 - < 0.01 1.00E00 1.00E00 prostate gland development (GO:0030850) 46 1 .01 + 74.57 1.33E-02 1.00E00 acylglycerol acyl-chain remodeling (GO:0036155) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intestinal lipid absorption (GO:1904729) 12 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride acyl-chain remodeling (GO:0036153) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylethanolamine acyl-chain remodeling (GO:0036152) 12 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylcholine acyl-chain remodeling (GO:0036151) 15 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylserine acyl-chain remodeling (GO:0036150) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein deubiquitination (GO:0016579) 111 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt-Frizzled-LRP5/6 complex assembly (GO:1904723) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of post-transcriptional gene silencing by regulatory ncRNA (GO:1900369) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of post-transcriptional gene silencing by regulatory ncRNA (GO:1900368) 30 0 .01 - < 0.01 1.00E00 1.00E00 vitamin B6 biosynthetic process (GO:0042819) 3 0 .00 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process (GO:0050428) 2 0 .00 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate metabolic process (GO:0050427) 16 0 .00 - < 0.01 1.00E00 1.00E00 pyridoxamine metabolic process (GO:0042818) 2 0 .00 - < 0.01 1.00E00 1.00E00 pyridoxal metabolic process (GO:0042817) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin B6 metabolic process (GO:0042816) 6 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-inhibiting G protein-coupled receptor signaling pathway (GO:0030845) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intermediate filament depolymerization (GO:0030844) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylinositol acyl-chain remodeling (GO:0036149) 6 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol acyl-chain remodeling (GO:0036148) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intermediate filament depolymerization (GO:0030842) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to mycotoxin (GO:0036146) 1 0 .00 - < 0.01 1.00E00 1.00E00 dendritic cell homeostasis (GO:0036145) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of AMPA glutamate receptor clustering (GO:1904719) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of AMPA glutamate receptor clustering (GO:1904717) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chaperone-mediated autophagy (GO:1904716) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chaperone-mediated autophagy (GO:1904715) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chaperone-mediated autophagy (GO:1904714) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein ubiquitination (GO:0016567) 593 0 .17 - < 0.01 1.00E00 1.00E00 regulation of Wnt-Frizzled-LRP5/6 complex assembly (GO:1904711) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, receptor recycling (GO:0016562) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, translocation (GO:0016561) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix, docking (GO:0016560) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of body hair planar orientation (GO:0048105) 3 0 .00 - < 0.01 1.00E00 1.00E00 establishment of body hair or bristle planar orientation (GO:0048104) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament polymerization (GO:0030838) 52 0 .02 - < 0.01 1.00E00 1.00E00 somatic stem cell division (GO:0048103) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of actin filament polymerization (GO:0030837) 53 0 .02 - < 0.01 1.00E00 1.00E00 autophagic cell death (GO:0048102) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament depolymerization (GO:0030836) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of actin filament depolymerization (GO:0030835) 39 0 .01 - < 0.01 1.00E00 1.00E00 regulation of actin filament depolymerization (GO:0030834) 54 0 .02 - < 0.01 1.00E00 1.00E00 regulation of actin filament polymerization (GO:0030833) 128 0 .04 - < 0.01 1.00E00 1.00E00 regulation of actin filament length (GO:0030832) 150 0 .04 - < 0.01 1.00E00 1.00E00 Schwann cell migration (GO:0036135) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granulosa cell apoptotic process (GO:1904708) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell proliferation (GO:1904707) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell proliferation (GO:1904706) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell proliferation (GO:1904705) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to adherens junction (GO:1904704) 1 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome fission (GO:0016559) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein import into peroxisome matrix (GO:0016558) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to adherens junction (GO:1904702) 2 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome membrane biogenesis (GO:0016557) 3 0 .00 - < 0.01 1.00E00 1.00E00 mRNA modification (GO:0016556) 19 0 .01 - < 0.01 1.00E00 1.00E00 cytidine to uridine editing (GO:0016554) 12 0 .00 - < 0.01 1.00E00 1.00E00 base conversion or substitution editing (GO:0016553) 18 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to platelet-derived growth factor stimulus (GO:0036120) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac endothelial to mesenchymal transition (GO:0061999) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein autoprocessing (GO:0016540) 27 0 .01 - < 0.01 1.00E00 1.00E00 Unclassified (UNCLASSIFIED) 2879 0 .84 - < 0.01 1.00E00 1.00E00 response to platelet-derived growth factor (GO:0036119) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide catabolic process (GO:0030813) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide catabolic process (GO:0030812) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of nucleotide catabolic process (GO:0030811) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide biosynthetic process (GO:0030810) 13 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty-acyl-CoA catabolic process (GO:0036116) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA catabolic process (GO:0036115) 6 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty-acyl-CoA catabolic process (GO:0036114) 4 0 .00 - < 0.01 1.00E00 1.00E00 very long-chain fatty-acyl-CoA catabolic process (GO:0036113) 1 0 .00 - < 0.01 1.00E00 1.00E00 medium-chain fatty-acyl-CoA metabolic process (GO:0036112) 6 0 .00 - < 0.01 1.00E00 1.00E00 very long-chain fatty-acyl-CoA metabolic process (GO:0036111) 2 0 .00 - < 0.01 1.00E00 1.00E00 intein-mediated protein splicing (GO:0016539) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiosis II cell cycle process (GO:0061983) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiosis I cell cycle process (GO:0061982) 129 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide biosynthetic process (GO:0030809) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleotide biosynthetic process (GO:0030808) 21 0 .01 - < 0.01 1.00E00 1.00E00 alpha-linolenic acid metabolic process (GO:0036109) 10 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene B4 metabolic process (GO:0036102) 5 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene B4 catabolic process (GO:0036101) 4 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene catabolic process (GO:0036100) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of angiogenesis (GO:0016525) 109 0 .03 - < 0.01 1.00E00 1.00E00 articular cartilage development (GO:0061975) 6 0 .00 - < 0.01 1.00E00 1.00E00 perichondral bone morphogenesis (GO:0061974) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane bone morphogenesis (GO:0061973) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of left/right asymmetry (GO:0061966) 7 0 .00 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) 38 0 .01 - < 0.01 1.00E00 1.00E00 rDNA heterochromatin formation (GO:0000183) 7 0 .00 - < 0.01 1.00E00 1.00E00 penetration of cumulus oophorus (GO:0061956) 1 0 .00 - < 0.01 1.00E00 1.00E00 midbody abscission (GO:0061952) 24 0 .01 - < 0.01 1.00E00 1.00E00 establishment of protein localization to plasma membrane (GO:0061951) 52 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein K48-linked ubiquitination (GO:0061945) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein K48-linked ubiquitination (GO:0061944) 2 0 .00 - < 0.01 1.00E00 1.00E00 MAPK cascade (GO:0000165) 223 0 .07 - < 0.01 1.00E00 1.00E00 phosphorelay signal transduction system (GO:0000160) 1 0 .00 - < 0.01 1.00E00 1.00E00 monocyte extravasation (GO:0035696) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitophagy by internal vacuole formation (GO:0035695) 1 0 .00 - < 0.01 1.00E00 1.00E00 c-di-GMP signaling (GO:0061939) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to somatodendritic compartment (GO:0061938) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial protein catabolic process (GO:0035694) 10 0 .00 - < 0.01 1.00E00 1.00E00 macrophage migration inhibitory factor signaling pathway (GO:0035691) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of erythrocyte enucleation (GO:0061931) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of erythrocyte enucleation (GO:0061930) 1 0 .00 - < 0.01 1.00E00 1.00E00 rRNA modification (GO:0000154) 35 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte degranulation (GO:0043299) 44 0 .01 - < 0.01 1.00E00 1.00E00 chemokine (C-C motif) ligand 5 signaling pathway (GO:0035689) 1 0 .00 - < 0.01 1.00E00 1.00E00 apical junction assembly (GO:0043297) 59 0 .02 - < 0.01 1.00E00 1.00E00 helper T cell diapedesis (GO:0035685) 2 0 .00 - < 0.01 1.00E00 1.00E00 helper T cell extravasation (GO:0035684) 3 0 .00 - < 0.01 1.00E00 1.00E00 memory T cell extravasation (GO:0035683) 2 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine propionylation (GO:0061921) 1 0 .00 - < 0.01 1.00E00 1.00E00 manchette disassembly (GO:1905199) 1 0 .00 - < 0.01 1.00E00 1.00E00 manchette assembly (GO:1905198) 10 0 .00 - < 0.01 1.00E00 1.00E00 posterior lateral line neuromast hair cell development (GO:0035677) 1 0 .00 - < 0.01 1.00E00 1.00E00 process utilizing autophagic mechanism (GO:0061919) 334 0 .10 - < 0.01 1.00E00 1.00E00 neuromast hair cell development (GO:0035675) 2 0 .00 - < 0.01 1.00E00 1.00E00 tricarboxylic acid transmembrane transport (GO:0035674) 2 0 .00 - < 0.01 1.00E00 1.00E00 oligopeptide transmembrane transport (GO:0035672) 15 0 .00 - < 0.01 1.00E00 1.00E00 autophagosome-endosome fusion (GO:0061910) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metaphase/anaphase transition of meiosis I (GO:1905188) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metaphase/anaphase transition of meiosis I (GO:1905186) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of mitotic spindle orientation (GO:0000132) 37 0 .01 - < 0.01 1.00E00 1.00E00 response to alkaloid (GO:0043279) 103 0 .03 - < 0.01 1.00E00 1.00E00 response to morphine (GO:0043278) 16 0 .00 - < 0.01 1.00E00 1.00E00 TRAM-dependent toll-like receptor 4 signaling pathway (GO:0035669) 3 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic cell clearance (GO:0043277) 36 0 .01 - < 0.01 1.00E00 1.00E00 TRAM-dependent toll-like receptor signaling pathway (GO:0035668) 3 0 .00 - < 0.01 1.00E00 1.00E00 anoikis (GO:0043276) 12 0 .00 - < 0.01 1.00E00 1.00E00 TRIF-dependent toll-like receptor signaling pathway (GO:0035666) 11 0 .00 - < 0.01 1.00E00 1.00E00 autophagosome-lysosome fusion (GO:0061909) 10 0 .00 - < 0.01 1.00E00 1.00E00 TIRAP-dependent toll-like receptor 4 signaling pathway (GO:0035665) 1 0 .00 - < 0.01 1.00E00 1.00E00 TIRAP-dependent toll-like receptor signaling pathway (GO:0035664) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monoatomic ion transport (GO:0043271) 109 0 .03 - < 0.01 1.00E00 1.00E00 autophagosome localization (GO:0061906) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monoatomic ion transport (GO:0043270) 205 0 .06 - < 0.01 1.00E00 1.00E00 glial cell activation (GO:0061900) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle tissue regeneration (GO:1905179) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle tissue regeneration (GO:1905178) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell dedifferentiation (GO:1905176) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell dedifferentiation (GO:1905174) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to phagocytic vesicle (GO:1905171) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by RNA polymerase II (GO:0000122) 938 0 .27 - < 0.01 1.00E00 1.00E00 regulation of monoatomic ion transport (GO:0043269) 445 0 .13 - < 0.01 1.00E00 1.00E00 positive regulation of potassium ion transport (GO:0043268) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of potassium ion transport (GO:0043267) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of potassium ion transport (GO:0043266) 94 0 .03 - < 0.01 1.00E00 1.00E00 interleukin-18-mediated signaling pathway (GO:0035655) 6 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-coated vesicle cargo loading, AP-3-mediated (GO:0035654) 7 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-coated vesicle cargo loading (GO:0035652) 7 0 .00 - < 0.01 1.00E00 1.00E00 replication fork processing (GO:0031297) 50 0 .01 - < 0.01 1.00E00 1.00E00 B cell costimulation (GO:0031296) 3 0 .00 - < 0.01 1.00E00 1.00E00 T cell costimulation (GO:0031295) 44 0 .01 - < 0.01 1.00E00 1.00E00 lymphocyte costimulation (GO:0031294) 45 0 .01 - < 0.01 1.00E00 1.00E00 membrane protein intracellular domain proteolysis (GO:0031293) 12 0 .00 - < 0.01 1.00E00 1.00E00 retinal ganglion cell axon guidance (GO:0031290) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to phagocytic vesicle (GO:1905169) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of double-strand break repair via homologous recombination (GO:1905168) 43 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lysosomal protein catabolic process (GO:1905167) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lysosomal protein catabolic process (GO:1905166) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lysosomal protein catabolic process (GO:1905165) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phagosome maturation (GO:1905164) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phagosome maturation (GO:1905162) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to phagocytic vesicle (GO:1905161) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of carbohydrate biosynthetic process (GO:0043255) 100 0 .03 - < 0.01 1.00E00 1.00E00 endosome to melanosome transport (GO:0035646) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein-containing complex assembly (GO:0043254) 430 0 .13 - < 0.01 1.00E00 1.00E00 enteric smooth muscle cell differentiation (GO:0035645) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphoanandamide dephosphorylation (GO:0035644) 1 0 .00 - < 0.01 1.00E00 1.00E00 sodium-independent organic anion transport (GO:0043252) 16 0 .00 - < 0.01 1.00E00 1.00E00 sodium-dependent organic anion transport (GO:0043251) 1 0 .00 - < 0.01 1.00E00 1.00E00 locomotory exploration behavior (GO:0035641) 17 0 .00 - < 0.01 1.00E00 1.00E00 exploration behavior (GO:0035640) 40 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of guanylate cyclase activity (GO:0031284) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of guanylate cyclase activity (GO:0031283) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of guanylate cyclase activity (GO:0031282) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cyclase activity (GO:0031281) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of membrane invagination (GO:1905155) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane invagination (GO:1905154) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine biosynthetic process (GO:0000105) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane invagination (GO:1905153) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated sodium channel activity (GO:1905152) 2 0 .00 - < 0.01 1.00E00 1.00E00 FMN biosynthetic process (GO:0009398) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of voltage-gated sodium channel activity (GO:1905151) 1 0 .00 - < 0.01 1.00E00 1.00E00 sulfate assimilation (GO:0000103) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of voltage-gated sodium channel activity (GO:1905150) 5 0 .00 - < 0.01 1.00E00 1.00E00 folic acid-containing compound catabolic process (GO:0009397) 4 0 .00 - < 0.01 1.00E00 1.00E00 erythrocyte maturation (GO:0043249) 21 0 .01 - < 0.01 1.00E00 1.00E00 sulfur amino acid transport (GO:0000101) 12 0 .00 - < 0.01 1.00E00 1.00E00 folic acid-containing compound biosynthetic process (GO:0009396) 8 0 .00 - < 0.01 1.00E00 1.00E00 proteasome assembly (GO:0043248) 14 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid catabolic process (GO:0009395) 48 0 .01 - < 0.01 1.00E00 1.00E00 telomere maintenance in response to DNA damage (GO:0043247) 15 0 .00 - < 0.01 1.00E00 1.00E00 2'-deoxyribonucleotide metabolic process (GO:0009394) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein-containing complex disassembly (GO:0043244) 131 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of protein-containing complex disassembly (GO:0043243) 38 0 .01 - < 0.01 1.00E00 1.00E00 response to stilbenoid (GO:0035634) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein-containing complex disassembly (GO:0043242) 80 0 .02 - < 0.01 1.00E00 1.00E00 maintenance of blood-brain barrier (GO:0035633) 39 0 .01 - < 0.01 1.00E00 1.00E00 bone mineralization involved in bone maturation (GO:0035630) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of pseudopodium assembly (GO:0031274) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pseudopodium assembly (GO:0031272) 13 0 .00 - < 0.01 1.00E00 1.00E00 lysosomal protein catabolic process (GO:1905146) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to acetylcholine (GO:1905145) 49 0 .01 - < 0.01 1.00E00 1.00E00 response to acetylcholine (GO:1905144) 52 0 .02 - < 0.01 1.00E00 1.00E00 eukaryotic translation initiation factor 2 complex assembly (GO:1905143) 1 0 .00 - < 0.01 1.00E00 1.00E00 translational attenuation (GO:0009386) 2 0 .00 - < 0.01 1.00E00 1.00E00 ceramide transport (GO:0035627) 17 0 .00 - < 0.01 1.00E00 1.00E00 receptor transactivation (GO:0035624) 4 0 .00 - < 0.01 1.00E00 1.00E00 renal D-glucose absorption (GO:0035623) 4 0 .00 - < 0.01 1.00E00 1.00E00 intrahepatic bile duct development (GO:0035622) 2 0 .00 - < 0.01 1.00E00 1.00E00 ER to Golgi ceramide transport (GO:0035621) 3 0 .00 - < 0.01 1.00E00 1.00E00 pseudopodium assembly (GO:0031269) 3 0 .00 - < 0.01 1.00E00 1.00E00 pseudopodium organization (GO:0031268) 4 0 .00 - < 0.01 1.00E00 1.00E00 biotin import across plasma membrane (GO:1905135) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of meiotic chromosome separation (GO:1905134) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic chromosome separation (GO:1905133) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of meiotic chromosome separation (GO:1905132) 6 0 .00 - < 0.01 1.00E00 1.00E00 stress granule disassembly (GO:0035617) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein branching point deglutamylation (GO:0035611) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein side chain deglutamylation (GO:0035610) 6 0 .00 - < 0.01 1.00E00 1.00E00 transmembrane transport from lysosomal lumen to cytosol (GO:0170063) 1 0 .00 - < 0.01 1.00E00 1.00E00 nutrient storage (GO:0170062) 50 0 .01 - < 0.01 1.00E00 1.00E00 C-terminal protein deglutamylation (GO:0035609) 6 0 .00 - < 0.01 1.00E00 1.00E00 myelin maintenance (GO:0043217) 17 0 .00 - < 0.01 1.00E00 1.00E00 protein deglutamylation (GO:0035608) 8 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development (GO:0035607) 2 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-cysteine S-trans-nitrosylation (GO:0035606) 2 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow (GO:0035604) 1 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in hemopoiesis (GO:0035603) 1 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow cell (GO:0035602) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein deacylation (GO:0035601) 22 0 .01 - < 0.01 1.00E00 1.00E00 tRNA methylthiolation (GO:0035600) 2 0 .00 - < 0.01 1.00E00 1.00E00 actin rod assembly (GO:0031247) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore (GO:1905116) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lateral attachment of mitotic spindle microtubules to kinetochore (GO:1905115) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to external biotic stimulus (GO:0043207) 1432 0 .42 - < 0.01 1.00E00 1.00E00 response to L-leucine (GO:0043201) 15 0 .00 - < 0.01 1.00E00 1.00E00 response to amino acid (GO:0043200) 124 0 .04 - < 0.01 1.00E00 1.00E00 non-proteinogenic amino acid catabolic process (GO:0170044) 18 0 .01 - < 0.01 1.00E00 1.00E00 non-proteinogenic amino acid biosynthetic process (GO:0170043) 15 0 .00 - < 0.01 1.00E00 1.00E00 non-proteinogenic amino acid metabolic process (GO:0170041) 59 0 .02 - < 0.01 1.00E00 1.00E00 proteinogenic amino acid catabolic process (GO:0170040) 74 0 .02 - < 0.01 1.00E00 1.00E00 proteinogenic amino acid metabolic process (GO:0170039) 160 0 .05 - < 0.01 1.00E00 1.00E00 proteinogenic amino acid biosynthetic process (GO:0170038) 52 0 .02 - < 0.01 1.00E00 1.00E00 export from the mitochondrion (GO:0170037) 4 0 .00 - < 0.01 1.00E00 1.00E00 import into the mitochondrion (GO:0170036) 47 0 .01 - < 0.01 1.00E00 1.00E00 L-amino acid catabolic process (GO:0170035) 74 0 .02 - < 0.01 1.00E00 1.00E00 L-amino acid biosynthetic process (GO:0170034) 48 0 .01 - < 0.01 1.00E00 1.00E00 L-amino acid metabolic process (GO:0170033) 159 0 .05 - < 0.01 1.00E00 1.00E00 auditory behavior (GO:0031223) 13 0 .00 - < 0.01 1.00E00 1.00E00 biomineral tissue development (GO:0031214) 107 0 .03 - < 0.01 1.00E00 1.00E00 post-translational protein targeting to membrane, translocation (GO:0031204) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to radiation (GO:0009314) 436 0 .13 - < 0.01 1.00E00 1.00E00 oligosaccharide catabolic process (GO:0009313) 16 0 .00 - < 0.01 1.00E00 1.00E00 oligosaccharide biosynthetic process (GO:0009312) 27 0 .01 - < 0.01 1.00E00 1.00E00 oligosaccharide metabolic process (GO:0009311) 64 0 .02 - < 0.01 1.00E00 1.00E00 amine catabolic process (GO:0009310) 20 0 .01 - < 0.01 1.00E00 1.00E00 tRNA transcription by RNA polymerase III (GO:0042797) 11 0 .00 - < 0.01 1.00E00 1.00E00 snRNA transcription by RNA polymerase III (GO:0042796) 9 0 .00 - < 0.01 1.00E00 1.00E00 snRNA transcription by RNA polymerase II (GO:0042795) 11 0 .00 - < 0.01 1.00E00 1.00E00 plastid transcription (GO:0042793) 7 0 .00 - < 0.01 1.00E00 1.00E00 5S class rRNA transcription by RNA polymerase III (GO:0042791) 6 0 .00 - < 0.01 1.00E00 1.00E00 nucleolar large rRNA transcription by RNA polymerase I (GO:0042790) 9 0 .00 - < 0.01 1.00E00 1.00E00 amine biosynthetic process (GO:0009309) 36 0 .01 - < 0.01 1.00E00 1.00E00 amine metabolic process (GO:0009308) 98 0 .03 - < 0.01 1.00E00 1.00E00 protein secretion (GO:0009306) 124 0 .04 - < 0.01 1.00E00 1.00E00 regulation of acinar cell proliferation (GO:1904697) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA transcription (GO:0009304) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle contraction (GO:1904695) 1 0 .00 - < 0.01 1.00E00 1.00E00 rRNA transcription (GO:0009303) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle contraction (GO:1904694) 4 0 .00 - < 0.01 1.00E00 1.00E00 midbrain morphogenesis (GO:1904693) 3 0 .00 - < 0.01 1.00E00 1.00E00 snRNA transcription (GO:0009301) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type B pancreatic cell proliferation (GO:1904692) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type B pancreatic cell proliferation (GO:1904691) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic translational initiation (GO:1904690) 7 0 .00 - < 0.01 1.00E00 1.00E00 mRNA transcription by RNA polymerase II (GO:0042789) 47 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of developmental pigmentation (GO:0048087) 9 0 .00 - < 0.01 1.00E00 1.00E00 tRNA 3'-end processing (GO:0042780) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of developmental pigmentation (GO:0048086) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic translational initiation (GO:1904689) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translational initiation (GO:1904688) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of metalloendopeptidase activity (GO:1904685) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metalloendopeptidase activity (GO:1904684) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metalloendopeptidase activity (GO:1904683) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to 3-methylcholanthrene (GO:1904681) 2 0 .00 - < 0.01 1.00E00 1.00E00 proton motive force-driven mitochondrial ATP synthesis (GO:0042776) 64 0 .02 - < 0.01 1.00E00 1.00E00 mitochondrial ATP synthesis coupled electron transport (GO:0042775) 91 0 .03 - < 0.01 1.00E00 1.00E00 ATP synthesis coupled electron transport (GO:0042773) 91 0 .03 - < 0.01 1.00E00 1.00E00 DNA damage response, signal transduction resulting in transcription (GO:0042772) 1 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator (GO:0042771) 33 0 .01 - < 0.01 1.00E00 1.00E00 signal transduction in response to DNA damage (GO:0042770) 147 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of eye pigmentation (GO:0048075) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of eye pigmentation (GO:0048074) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eye pigmentation (GO:0048073) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of developmental pigmentation (GO:0048070) 15 0 .00 - < 0.01 1.00E00 1.00E00 myo-inositol import across plasma membrane (GO:1904679) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of somatic stem cell division (GO:1904677) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of somatic stem cell division (GO:1904675) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of somatic stem cell population maintenance (GO:1904674) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of somatic stem cell population maintenance (GO:1904673) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of somatic stem cell population maintenance (GO:1904672) 11 0 .00 - < 0.01 1.00E00 1.00E00 eye pigmentation (GO:0048069) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sulfur metabolic process (GO:0042762) 16 0 .00 - < 0.01 1.00E00 1.00E00 very long-chain fatty acid biosynthetic process (GO:0042761) 13 0 .00 - < 0.01 1.00E00 1.00E00 developmental pigmentation (GO:0048066) 42 0 .01 - < 0.01 1.00E00 1.00E00 very long-chain fatty acid catabolic process (GO:0042760) 7 0 .00 - < 0.01 1.00E00 1.00E00 male germ-line stem cell population maintenance (GO:0036098) 1 0 .00 - < 0.01 1.00E00 1.00E00 ATP export (GO:1904669) 10 0 .00 - < 0.01 1.00E00 1.00E00 germ cell proliferation (GO:0036093) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ubiquitin protein ligase activity (GO:1904668) 9 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) 23 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ubiquitin protein ligase activity (GO:1904667) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ubiquitin protein ligase activity (GO:1904666) 18 0 .01 - < 0.01 1.00E00 1.00E00 cleavage furrow ingression (GO:0036090) 2 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty acid biosynthetic process (GO:0042759) 28 0 .01 - < 0.01 1.00E00 1.00E00 long-chain fatty acid catabolic process (GO:0042758) 9 0 .00 - < 0.01 1.00E00 1.00E00 drinking behavior (GO:0042756) 11 0 .00 - < 0.01 1.00E00 1.00E00 eating behavior (GO:0042755) 35 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of circadian rhythm (GO:0042754) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of circadian rhythm (GO:0042753) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of circadian rhythm (GO:0042752) 113 0 .03 - < 0.01 1.00E00 1.00E00 post-embryonic eye morphogenesis (GO:0048050) 7 0 .00 - < 0.01 1.00E00 1.00E00 cleavage furrow formation (GO:0036089) 7 0 .00 - < 0.01 1.00E00 1.00E00 D-serine catabolic process (GO:0036088) 1 0 .00 - < 0.01 1.00E00 1.00E00 GDP-fucose import into Golgi lumen (GO:0036085) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-glucose transmembrane transport (GO:1904659) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of fat cell apoptotic process (GO:1904651) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle (GO:0042749) 19 0 .01 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle, non-REM sleep (GO:0042748) 1 0 .00 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle (GO:0042745) 5 0 .00 - < 0.01 1.00E00 1.00E00 hydrogen peroxide catabolic process (GO:0042744) 26 0 .01 - < 0.01 1.00E00 1.00E00 hydrogen peroxide metabolic process (GO:0042743) 40 0 .01 - < 0.01 1.00E00 1.00E00 embryonic eye morphogenesis (GO:0048048) 35 0 .01 - < 0.01 1.00E00 1.00E00 defense response to bacterium (GO:0042742) 312 0 .09 - < 0.01 1.00E00 1.00E00 focal adhesion assembly (GO:0048041) 29 0 .01 - < 0.01 1.00E00 1.00E00 ligamentous ossification (GO:0036076) 1 0 .00 - < 0.01 1.00E00 1.00E00 replacement ossification (GO:0036075) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of fat cell apoptotic process (GO:1904649) 2 0 .00 - < 0.01 1.00E00 1.00E00 direct ossification (GO:0036072) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to amyloid-beta (GO:1904646) 41 0 .01 - < 0.01 1.00E00 1.00E00 N-glycan fucosylation (GO:0036071) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to amyloid-beta (GO:1904645) 52 0 .02 - < 0.01 1.00E00 1.00E00 response to curcumin (GO:1904643) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to methionine (GO:1904640) 6 0 .00 - < 0.01 1.00E00 1.00E00 embryonic digit morphogenesis (GO:0042733) 60 0 .02 - < 0.01 1.00E00 1.00E00 D-xylose metabolic process (GO:0042732) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900281) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900280) 1 0 .00 - < 0.01 1.00E00 1.00E00 fibrinolysis (GO:0042730) 19 0 .01 - < 0.01 1.00E00 1.00E00 heme O biosynthetic process (GO:0048034) 9 0 .00 - < 0.01 1.00E00 1.00E00 heme O metabolic process (GO:0048033) 9 0 .00 - < 0.01 1.00E00 1.00E00 protein O-linked fucosylation (GO:0036066) 4 0 .00 - < 0.01 1.00E00 1.00E00 fucosylation (GO:0036065) 16 0 .00 - < 0.01 1.00E00 1.00E00 response to resveratrol (GO:1904638) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to ionomycin (GO:1904637) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to ionomycin (GO:1904636) 5 0 .00 - < 0.01 1.00E00 1.00E00 slit diaphragm assembly (GO:0036060) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of podocyte apoptotic process (GO:1904635) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of podocyte apoptotic process (GO:1904633) 2 0 .00 - < 0.01 1.00E00 1.00E00 farnesol catabolic process (GO:0016488) 2 0 .00 - < 0.01 1.00E00 1.00E00 farnesol metabolic process (GO:0016487) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to glucoside (GO:1904631) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptide hormone processing (GO:0016486) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of CD4-positive, alpha-beta T cell costimulation (GO:1900279) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein processing (GO:0016485) 186 0 .05 - < 0.01 1.00E00 1.00E00 flavin-containing compound catabolic process (GO:0042728) 1 0 .00 - < 0.01 1.00E00 1.00E00 flavin-containing compound biosynthetic process (GO:0042727) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytosolic transport (GO:0016482) 135 0 .04 - < 0.01 1.00E00 1.00E00 flavin-containing compound metabolic process (GO:0042726) 6 0 .00 - < 0.01 1.00E00 1.00E00 thiamine-containing compound biosynthetic process (GO:0042724) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by RNA polymerase III (GO:0016480) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of long-term synaptic potentiation (GO:1900273) 23 0 .01 - < 0.01 1.00E00 1.00E00 thiamine-containing compound metabolic process (GO:0042723) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of long-term synaptic potentiation (GO:1900272) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of long-term synaptic potentiation (GO:1900271) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA splicing, via spliceosome (GO:0048026) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA splicing, via spliceosome (GO:0048025) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of mRNA splicing, via spliceosome (GO:0048024) 111 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of melanin biosynthetic process (GO:0048023) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of melanin biosynthetic process (GO:0048022) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of melanin biosynthetic process (GO:0048021) 16 0 .00 - < 0.01 1.00E00 1.00E00 filtration diaphragm assembly (GO:0036058) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to phorbol 13-acetate 12-myristate (GO:1904628) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to phorbol 13-acetate 12-myristate (GO:1904627) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by RNA polymerase I (GO:0016479) 11 0 .00 - < 0.01 1.00E00 1.00E00 cell migration (GO:0016477) 934 0 .27 - < 0.01 1.00E00 1.00E00 regulation of embryonic cell shape (GO:0016476) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-directed DNA polymerase activity (GO:1900264) 9 0 .00 - < 0.01 1.00E00 1.00E00 sperm ejaculation (GO:0042713) 5 0 .00 - < 0.01 1.00E00 1.00E00 maternal behavior (GO:0042711) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RNA-dependent RNA polymerase activity (GO:1900260) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylinositol-mediated signaling (GO:0048015) 24 0 .01 - < 0.01 1.00E00 1.00E00 Tie signaling pathway (GO:0048014) 4 0 .00 - < 0.01 1.00E00 1.00E00 ephrin receptor signaling pathway (GO:0048013) 84 0 .02 - < 0.01 1.00E00 1.00E00 hepatocyte growth factor receptor signaling pathway (GO:0048012) 56 0 .02 - < 0.01 1.00E00 1.00E00 neurotrophin TRK receptor signaling pathway (GO:0048011) 15 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor receptor signaling pathway (GO:0048010) 80 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-lysine desuccinylation (GO:0036049) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein desuccinylation (GO:0036048) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-lysine demalonylation (GO:0036047) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein demalonylation (GO:0036046) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin binding (GO:1904616) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to biphenyl (GO:1904614) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to 2,3,7,8-tetrachlorodibenzodioxine (GO:1904613) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to 2,3,7,8-tetrachlorodibenzodioxine (GO:1904612) 7 0 .00 - < 0.01 1.00E00 1.00E00 eye photoreceptor cell fate commitment (GO:0042706) 1 0 .00 - < 0.01 1.00E00 1.00E00 uterine wall breakdown (GO:0042704) 2 0 .00 - < 0.01 1.00E00 1.00E00 insulin-like growth factor receptor signaling pathway (GO:0048009) 81 0 .02 - < 0.01 1.00E00 1.00E00 platelet-derived growth factor receptor signaling pathway (GO:0048008) 83 0 .02 - < 0.01 1.00E00 1.00E00 antigen processing and presentation, exogenous lipid antigen via MHC class Ib (GO:0048007) 7 0 .00 - < 0.01 1.00E00 1.00E00 progesterone secretion (GO:0042701) 2 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation, endogenous lipid antigen via MHC class Ib (GO:0048006) 5 0 .00 - < 0.01 1.00E00 1.00E00 luteinizing hormone signaling pathway (GO:0042700) 2 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of lipid antigen via MHC class Ib (GO:0048003) 7 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of peptide antigen (GO:0048002) 68 0 .02 - < 0.01 1.00E00 1.00E00 CD8-positive, alpha-beta T cell activation (GO:0036037) 11 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride storage (GO:0030730) 1 0 .00 - < 0.01 1.00E00 1.00E00 osteoclast development (GO:0036035) 10 0 .00 - < 0.01 1.00E00 1.00E00 fat cell apoptotic process (GO:1904606) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic translational elongation (GO:1900249) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic translational elongation (GO:1900248) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic translational elongation (GO:1900247) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of RIG-I signaling pathway (GO:1900246) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of MDA-5 signaling pathway (GO:1900245) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle endocytosis (GO:1900244) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle endocytosis (GO:1900242) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of phenotypic switching (GO:1900240) 2 0 .00 - < 0.01 1.00E00 1.00E00 ovulation (GO:0030728) 14 0 .00 - < 0.01 1.00E00 1.00E00 embryonic skeletal limb joint morphogenesis (GO:0036023) 3 0 .00 - < 0.01 1.00E00 1.00E00 limb joint morphogenesis (GO:0036022) 7 0 .00 - < 0.01 1.00E00 1.00E00 somatic recombination of immunoglobulin gene segments (GO:0016447) 34 0 .01 - < 0.01 1.00E00 1.00E00 somatic hypermutation of immunoglobulin genes (GO:0016446) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phenotypic switching (GO:1900239) 3 0 .00 - < 0.01 1.00E00 1.00E00 somatic diversification of immunoglobulins (GO:0016445) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway (GO:1900238) 3 0 .00 - < 0.01 1.00E00 1.00E00 somatic cell DNA recombination (GO:0016444) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Kit signaling pathway (GO:1900235) 2 0 .00 - < 0.01 1.00E00 1.00E00 post-transcriptional gene silencing (GO:0016441) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of Kit signaling pathway (GO:1900234) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of astrocyte activation (GO:0061890) 1 0 .00 - < 0.01 1.00E00 1.00E00 P granule organization (GO:0030719) 6 0 .00 - < 0.01 1.00E00 1.00E00 germ-line stem cell population maintenance (GO:0030718) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to erythropoietin (GO:0036018) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to erythropoietin (GO:0036017) 9 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-3 (GO:0036016) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to interleukin-3 (GO:0036015) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to endosome (GO:0036010) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of astrocyte activation (GO:0061889) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of astrocyte activation (GO:0061888) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of single-species biofilm formation in or on host organism (GO:1900229) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of single-species biofilm formation in or on host organism (GO:1900228) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mini excitatory postsynaptic potential (GO:0061886) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of NLRP3 inflammasome complex assembly (GO:1900227) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mini excitatory postsynaptic potential (GO:0061885) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of NLRP3 inflammasome complex assembly (GO:1900226) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mini excitatory postsynaptic potential (GO:0061884) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NLRP3 inflammasome complex assembly (GO:1900225) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of amyloid-beta clearance (GO:1900223) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde axonal transport of mitochondrion (GO:0061881) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid-beta clearance (GO:1900222) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anterograde axonal transport of mitochondrion (GO:0061880) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amyloid-beta clearance (GO:1900221) 18 0 .01 - < 0.01 1.00E00 1.00E00 cytoskeleton-dependent intracellular transport (GO:0030705) 198 0 .06 - < 0.01 1.00E00 1.00E00 vitelline membrane formation (GO:0030704) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to macrophage colony-stimulating factor stimulus (GO:0036006) 55 0 .02 - < 0.01 1.00E00 1.00E00 response to macrophage colony-stimulating factor (GO:0036005) 59 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in metanephric nephron tubule development (GO:1900218) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in metanephric nephron tubule development (GO:1900217) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell contraction (GO:0061874) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell contraction (GO:0061873) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process involved in metanephric collecting duct development (GO:1900215) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptotic process involved in metanephric collecting duct development (GO:1900214) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in metanephros development (GO:1900212) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatic stellate cell migration (GO:0061870) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in metanephros development (GO:1900211) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiolipin metabolic process (GO:1900210) 2 0 .00 - < 0.01 1.00E00 1.00E00 sulfur amino acid catabolic process (GO:0000098) 10 0 .00 - < 0.01 1.00E00 1.00E00 sulfur amino acid biosynthetic process (GO:0000097) 16 0 .00 - < 0.01 1.00E00 1.00E00 sulfur amino acid metabolic process (GO:0000096) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of hepatic stellate cell migration (GO:0061869) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiolipin metabolic process (GO:1900208) 4 0 .00 - < 0.01 1.00E00 1.00E00 polarized secretion of basement membrane proteins in epithelium (GO:0061865) 1 0 .00 - < 0.01 1.00E00 1.00E00 basement membrane constituent secretion (GO:0061864) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell apoptotic process involved in metanephros development (GO:1900200) 1 0 .00 - < 0.01 1.00E00 1.00E00 G2/M transition of mitotic cell cycle (GO:0000086) 51 0 .01 - < 0.01 1.00E00 1.00E00 G1/S transition of mitotic cell cycle (GO:0000082) 80 0 .02 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum stress-induced pre-emptive quality control (GO:0061857) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuroblast migration (GO:0061855) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuroblast migration (GO:0061853) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cyclin-dependent protein serine/threonine kinase activity (GO:0000079) 47 0 .01 - < 0.01 1.00E00 1.00E00 DNA damage checkpoint signaling (GO:0000077) 100 0 .03 - < 0.01 1.00E00 1.00E00 DNA replication checkpoint signaling (GO:0000076) 20 0 .01 - < 0.01 1.00E00 1.00E00 cell cycle checkpoint signaling (GO:0000075) 154 0 .04 - < 0.01 1.00E00 1.00E00 mitotic sister chromatid segregation (GO:0000070) 143 0 .04 - < 0.01 1.00E00 1.00E00 response to cholecystokinin (GO:0061847) 2 0 .00 - < 0.01 1.00E00 1.00E00 antimicrobial humoral immune response mediated by antimicrobial peptide (GO:0061844) 121 0 .04 - < 0.01 1.00E00 1.00E00 microtubule organizing center localization (GO:0061842) 33 0 .01 - < 0.01 1.00E00 1.00E00 neuropeptide processing (GO:0061837) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to extracellular region (GO:0035592) 127 0 .04 - < 0.01 1.00E00 1.00E00 purinergic nucleotide receptor signaling pathway (GO:0035590) 29 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to tricellular tight junction (GO:0061833) 3 0 .00 - < 0.01 1.00E00 1.00E00 ribosomal small subunit export from nucleus (GO:0000056) 7 0 .00 - < 0.01 1.00E00 1.00E00 ribosomal large subunit export from nucleus (GO:0000055) 7 0 .00 - < 0.01 1.00E00 1.00E00 ribosomal subunit export from nucleus (GO:0000054) 12 0 .00 - < 0.01 1.00E00 1.00E00 argininosuccinate metabolic process (GO:0000053) 1 0 .00 - < 0.01 1.00E00 1.00E00 citrulline metabolic process (GO:0000052) 6 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled purinergic nucleotide receptor signaling pathway (GO:0035589) 13 0 .00 - < 0.01 1.00E00 1.00E00 urea cycle (GO:0000050) 12 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled purinergic receptor signaling pathway (GO:0035588) 9 0 .00 - < 0.01 1.00E00 1.00E00 sequestering of TGFbeta in extracellular matrix (GO:0035583) 4 0 .00 - < 0.01 1.00E00 1.00E00 sequestering of BMP in extracellular matrix (GO:0035582) 4 0 .00 - < 0.01 1.00E00 1.00E00 sequestering of extracellular ligand from receptor (GO:0035581) 10 0 .00 - < 0.01 1.00E00 1.00E00 cytosolic ciliogenesis (GO:0061824) 5 0 .00 - < 0.01 1.00E00 1.00E00 telomeric D-loop disassembly (GO:0061820) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of guanyl-nucleotide exchange factor activity (GO:1905099) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of guanyl-nucleotide exchange factor activity (GO:1905098) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of guanyl-nucleotide exchange factor activity (GO:1905097) 6 0 .00 - < 0.01 1.00E00 1.00E00 autophagosome assembly (GO:0000045) 81 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of type 2 mitophagy (GO:1905091) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type 2 mitophagy (GO:1905090) 2 0 .00 - < 0.01 1.00E00 1.00E00 transition metal ion transport (GO:0000041) 99 0 .03 - < 0.01 1.00E00 1.00E00 telomeric DNA-containing double minutes formation (GO:0061819) 3 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum-plasma membrane tethering (GO:0061817) 6 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine trimethylation (GO:0035573) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine dimethylation (GO:0035572) 1 0 .00 - < 0.01 1.00E00 1.00E00 vacuolar sequestering (GO:0043181) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-serine methylation (GO:0035570) 1 0 .00 - < 0.01 1.00E00 1.00E00 electron transport coupled proton transport (GO:0015990) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type 2 mitophagy (GO:1905089) 13 0 .00 - < 0.01 1.00E00 1.00E00 very long-chain fatty acid metabolic process (GO:0000038) 35 0 .01 - < 0.01 1.00E00 1.00E00 rhythmic excitation (GO:0043179) 1 0 .00 - < 0.01 1.00E00 1.00E00 N-terminal peptidyl-proline methylation (GO:0035568) 1 0 .00 - < 0.01 1.00E00 1.00E00 non-canonical Wnt signaling pathway (GO:0035567) 50 0 .01 - < 0.01 1.00E00 1.00E00 regulation of metanephros size (GO:0035566) 2 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside salvage (GO:0043174) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pronephros size (GO:0035565) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide salvage (GO:0043173) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of kidney size (GO:0035564) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chromatin binding (GO:0035563) 8 0 .00 - < 0.01 1.00E00 1.00E00 peptide catabolic process (GO:0043171) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of chromatin binding (GO:0035562) 2 0 .00 - < 0.01 1.00E00 1.00E00 macromolecule metabolic process (GO:0043170) 5398 1 1.57 - .64 1.00E00 1.00E00 energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) 4 0 .00 - < 0.01 1.00E00 1.00E00 proton motive force-driven ATP synthesis (GO:0015986) 73 0 .02 - < 0.01 1.00E00 1.00E00 energy derivation by oxidation of organic compounds (GO:0015980) 269 0 .08 - < 0.01 1.00E00 1.00E00 ribosomal small subunit assembly (GO:0000028) 21 0 .01 - < 0.01 1.00E00 1.00E00 ribosomal large subunit assembly (GO:0000027) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of tight junction disassembly (GO:1905075) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tight junction disassembly (GO:1905073) 5 0 .00 - < 0.01 1.00E00 1.00E00 maltose catabolic process (GO:0000025) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac jelly development (GO:1905072) 3 0 .00 - < 0.01 1.00E00 1.00E00 maltose metabolic process (GO:0000023) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic spindle elongation (GO:0000022) 11 0 .00 - < 0.01 1.00E00 1.00E00 anterior visceral endoderm cell migration (GO:1905070) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-alanine catabolic process (GO:0055130) 1 0 .00 - < 0.01 1.00E00 1.00E00 intracellular signal transduction (GO:0035556) 1767 0 .52 - < 0.01 1.00E00 1.00E00 cell envelope organization (GO:0043163) 2 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162) 37 0 .01 - < 0.01 1.00E00 1.00E00 proteasome-mediated ubiquitin-dependent protein catabolic process (GO:0043161) 367 0 .11 - < 0.01 1.00E00 1.00E00 L-proline biosynthetic process (GO:0055129) 6 0 .00 - < 0.01 1.00E00 1.00E00 allantois development (GO:1905069) 4 0 .00 - < 0.01 1.00E00 1.00E00 vibrational conductance of sound to the inner ear (GO:0055127) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic recombination (GO:0000019) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA recombination (GO:0000018) 141 0 .04 - < 0.01 1.00E00 1.00E00 alpha-glucoside transport (GO:0000017) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular associated smooth muscle cell differentiation (GO:1905065) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vascular associated smooth muscle cell differentiation (GO:1905064) 8 0 .00 - < 0.01 1.00E00 1.00E00 digestive system development (GO:0055123) 150 0 .04 - < 0.01 1.00E00 1.00E00 regulation of vascular associated smooth muscle cell differentiation (GO:1905063) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardioblast proliferation (GO:1905062) 1 0 .00 - < 0.01 1.00E00 1.00E00 single strand break repair (GO:0000012) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to cation stress (GO:0043157) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of left/right asymmetry in nervous system (GO:0035545) 2 0 .00 - < 0.01 1.00E00 1.00E00 entrainment of circadian clock by photoperiod (GO:0043153) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of SNARE complex assembly (GO:0035544) 2 0 .00 - < 0.01 1.00E00 1.00E00 induction of bacterial agglutination (GO:0043152) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of SNARE complex assembly (GO:0035543) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of SNARE complex assembly (GO:0035542) 14 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine tetraphosphate biosynthetic process (GO:0015966) 2 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine tetraphosphate metabolic process (GO:0015965) 2 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine triphosphate catabolic process (GO:0015964) 1 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine triphosphate metabolic process (GO:0015962) 1 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate catabolic process (GO:0015961) 6 0 .00 - < 0.01 1.00E00 1.00E00 relaxation of cardiac muscle (GO:0055119) 14 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate biosynthetic process (GO:0015960) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle contraction (GO:0055118) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle contraction (GO:0055117) 74 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of base-excision repair (GO:1905053) 2 0 .00 - < 0.01 1.00E00 1.00E00 epiboly involved in gastrulation with mouth forming second (GO:0055113) 1 0 .00 - < 0.01 1.00E00 1.00E00 mRNA transcription (GO:0009299) 52 0 .02 - < 0.01 1.00E00 1.00E00 regulation of base-excision repair (GO:1905051) 3 0 .00 - < 0.01 1.00E00 1.00E00 ingression involved in gastrulation with mouth forming second (GO:0055111) 1 0 .00 - < 0.01 1.00E00 1.00E00 GDP-mannose biosynthetic process (GO:0009298) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial genome maintenance (GO:0000002) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of metallopeptidase activity (GO:1905050) 3 0 .00 - < 0.01 1.00E00 1.00E00 stress fiber assembly (GO:0043149) 22 0 .01 - < 0.01 1.00E00 1.00E00 sno(s)RNA processing (GO:0043144) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translation by machinery localization (GO:0043143) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptide modification (GO:0031179) 8 0 .00 - < 0.01 1.00E00 1.00E00 diadenosine polyphosphate metabolic process (GO:0015959) 8 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection development (GO:0031175) 721 0 .21 - < 0.01 1.00E00 1.00E00 otolith mineralization completed early in development (GO:0031173) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of metallopeptidase activity (GO:1905049) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of metallopeptidase activity (GO:1905048) 9 0 .00 - < 0.01 1.00E00 1.00E00 Golgi to secretory granule transport (GO:0055107) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Schwann cell proliferation involved in axon regeneration (GO:1905045) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell proliferation involved in axon regeneration (GO:1905044) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelium regeneration (GO:1905042) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelium regeneration (GO:1905041) 2 0 .00 - < 0.01 1.00E00 1.00E00 otic placode development (GO:1905040) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA replication, removal of RNA primer (GO:0043137) 4 0 .00 - < 0.01 1.00E00 1.00E00 retrograde transport, plasma membrane to Golgi (GO:0035526) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hindgut contraction (GO:0043134) 2 0 .00 - < 0.01 1.00E00 1.00E00 proline transmembrane transport (GO:0035524) 9 0 .00 - < 0.01 1.00E00 1.00E00 NAD transport (GO:0043132) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein K29-linked deubiquitination (GO:0035523) 4 0 .00 - < 0.01 1.00E00 1.00E00 erythrocyte enucleation (GO:0043131) 4 0 .00 - < 0.01 1.00E00 1.00E00 monoubiquitinated protein deubiquitination (GO:0035520) 10 0 .00 - < 0.01 1.00E00 1.00E00 rRNA methylation (GO:0031167) 25 0 .01 - < 0.01 1.00E00 1.00E00 nucleobase-containing small molecule interconversion (GO:0015949) 8 0 .00 - < 0.01 1.00E00 1.00E00 metallo-sulfur cluster assembly (GO:0031163) 26 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylinositol catabolic process (GO:0031161) 2 0 .00 - < 0.01 1.00E00 1.00E00 formate metabolic process (GO:0015942) 6 0 .00 - < 0.01 1.00E00 1.00E00 carboxylic acid transmembrane transport (GO:1905039) 139 0 .04 - < 0.01 1.00E00 1.00E00 regulation of membrane lipid metabolic process (GO:1905038) 19 0 .01 - < 0.01 1.00E00 1.00E00 autophagosome organization (GO:1905037) 89 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of antifungal innate immune response (GO:1905036) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antifungal innate immune response (GO:1905035) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antifungal innate immune response (GO:1905034) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905033) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905032) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during cardiac muscle cell action potential (GO:1905031) 5 0 .00 - < 0.01 1.00E00 1.00E00 surfactant homeostasis (GO:0043129) 21 0 .01 - < 0.01 1.00E00 1.00E00 protein K29-linked ubiquitination (GO:0035519) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of canonical NF-kappaB signal transduction (GO:0043124) 69 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of canonical NF-kappaB signal transduction (GO:0043123) 220 0 .06 - < 0.01 1.00E00 1.00E00 regulation of canonical NF-kappaB signal transduction (GO:0043122) 299 0 .09 - < 0.01 1.00E00 1.00E00 oxidative RNA demethylation (GO:0035513) 2 0 .00 - < 0.01 1.00E00 1.00E00 pantothenate metabolic process (GO:0015939) 7 0 .00 - < 0.01 1.00E00 1.00E00 coenzyme A catabolic process (GO:0015938) 4 0 .00 - < 0.01 1.00E00 1.00E00 coenzyme A biosynthetic process (GO:0015937) 10 0 .00 - < 0.01 1.00E00 1.00E00 coenzyme A metabolic process (GO:0015936) 18 0 .01 - < 0.01 1.00E00 1.00E00 nucleobase-containing compound transport (GO:0015931) 233 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905026) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905025) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during ventricular cardiac muscle cell action potential (GO:1905024) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to pH (GO:0009268) 43 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to starvation (GO:0009267) 188 0 .05 - < 0.01 1.00E00 1.00E00 response to temperature stimulus (GO:0009266) 165 0 .05 - < 0.01 1.00E00 1.00E00 2'-deoxyribonucleotide biosynthetic process (GO:0009265) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular permeability (GO:0043117) 18 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribonucleotide catabolic process (GO:0009264) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vascular permeability (GO:0043116) 19 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribonucleotide biosynthetic process (GO:0009263) 15 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleotide metabolic process (GO:0009262) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of vascular permeability (GO:0043114) 49 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleotide catabolic process (GO:0009261) 87 0 .03 - < 0.01 1.00E00 1.00E00 receptor clustering (GO:0043113) 47 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleotide biosynthetic process (GO:0009260) 159 0 .05 - < 0.01 1.00E00 1.00E00 receptor metabolic process (GO:0043112) 44 0 .01 - < 0.01 1.00E00 1.00E00 metanephric part of ureteric bud development (GO:0035502) 4 0 .00 - < 0.01 1.00E00 1.00E00 replication fork arrest (GO:0043111) 4 0 .00 - < 0.01 1.00E00 1.00E00 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) 42 0 .01 - < 0.01 1.00E00 1.00E00 anaphase-promoting complex-dependent catabolic process (GO:0031145) 22 0 .01 - < 0.01 1.00E00 1.00E00 proteasome localization (GO:0031144) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipopolysaccharide transport (GO:0015920) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleotide metabolic process (GO:0009259) 308 0 .09 - < 0.01 1.00E00 1.00E00 regulation of 'de novo' NAD biosynthetic process from L-tryptophan (GO:1905012) 1 0 .00 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate catabolic process (GO:0009258) 3 0 .00 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate biosynthetic process (GO:0009257) 2 0 .00 - < 0.01 1.00E00 1.00E00 10-formyltetrahydrofolate metabolic process (GO:0009256) 6 0 .00 - < 0.01 1.00E00 1.00E00 peptidoglycan catabolic process (GO:0009253) 6 0 .00 - < 0.01 1.00E00 1.00E00 glucan catabolic process (GO:0009251) 21 0 .01 - < 0.01 1.00E00 1.00E00 glucan biosynthetic process (GO:0009250) 19 0 .01 - < 0.01 1.00E00 1.00E00 hypoxanthine salvage (GO:0043103) 2 0 .00 - < 0.01 1.00E00 1.00E00 amino acid salvage (GO:0043102) 7 0 .00 - < 0.01 1.00E00 1.00E00 purine-containing compound salvage (GO:0043101) 25 0 .01 - < 0.01 1.00E00 1.00E00 peroxisomal membrane transport (GO:0015919) 22 0 .01 - < 0.01 1.00E00 1.00E00 sterol transport (GO:0015918) 79 0 .02 - < 0.01 1.00E00 1.00E00 aminophospholipid transport (GO:0015917) 9 0 .00 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA transport (GO:0015916) 3 0 .00 - < 0.01 1.00E00 1.00E00 sister chromatid biorientation (GO:0031134) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of axon diameter (GO:0031133) 6 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid transport (GO:0015914) 103 0 .03 - < 0.01 1.00E00 1.00E00 short-chain fatty acid transmembrane transport (GO:0015913) 2 0 .00 - < 0.01 1.00E00 1.00E00 short-chain fatty acid transport (GO:0015912) 3 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty acid import across plasma membrane (GO:0015911) 4 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty acid import into peroxisome (GO:0015910) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905007) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905006) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial to mesenchymal transition involved in endocardial cushion formation (GO:1905005) 4 0 .00 - < 0.01 1.00E00 1.00E00 picolinic acid biosynthetic process (GO:1905004) 1 0 .00 - < 0.01 1.00E00 1.00E00 picolinic acid metabolic process (GO:1905003) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein lipoylation (GO:0009249) 5 0 .00 - < 0.01 1.00E00 1.00E00 glycolipid biosynthetic process (GO:0009247) 78 0 .02 - < 0.01 1.00E00 1.00E00 regulation of membrane repolarization during atrial cardiac muscle cell action potential (GO:1905000) 1 0 .00 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate biosynthetic process (GO:0009240) 5 0 .00 - < 0.01 1.00E00 1.00E00 inductive cell-cell signaling (GO:0031129) 1 0 .00 - < 0.01 1.00E00 1.00E00 developmental induction (GO:0031128) 34 0 .01 - < 0.01 1.00E00 1.00E00 long-chain fatty acid transport (GO:0015909) 55 0 .02 - < 0.01 1.00E00 1.00E00 sno(s)RNA 3'-end processing (GO:0031126) 12 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid transport (GO:0015908) 94 0 .03 - < 0.01 1.00E00 1.00E00 rRNA 3'-end processing (GO:0031125) 11 0 .00 - < 0.01 1.00E00 1.00E00 mRNA 3'-end processing (GO:0031124) 34 0 .01 - < 0.01 1.00E00 1.00E00 RNA 3'-end processing (GO:0031123) 86 0 .03 - < 0.01 1.00E00 1.00E00 cytoplasmic microtubule organization (GO:0031122) 65 0 .02 - < 0.01 1.00E00 1.00E00 tetracycline transmembrane transport (GO:0015904) 1 0 .00 - < 0.01 1.00E00 1.00E00 snRNA pseudouridine synthesis (GO:0031120) 3 0 .00 - < 0.01 1.00E00 1.00E00 siderophore metabolic process (GO:0009237) 1 0 .00 - < 0.01 1.00E00 1.00E00 cobalamin metabolic process (GO:0009235) 9 0 .00 - < 0.01 1.00E00 1.00E00 menaquinone biosynthetic process (GO:0009234) 1 0 .00 - < 0.01 1.00E00 1.00E00 menaquinone metabolic process (GO:0009233) 6 0 .00 - < 0.01 1.00E00 1.00E00 riboflavin biosynthetic process (GO:0009231) 1 0 .00 - < 0.01 1.00E00 1.00E00 tRNA pseudouridine synthesis (GO:0031119) 6 0 .00 - < 0.01 1.00E00 1.00E00 rRNA pseudouridine synthesis (GO:0031118) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule depolymerization (GO:0031117) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule polymerization (GO:0031116) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule polymerization (GO:0031115) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule depolymerization (GO:0031114) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of microtubule polymerization (GO:0031113) 65 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule polymerization or depolymerization (GO:0031112) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule polymerization or depolymerization (GO:0031111) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of microtubule polymerization or depolymerization (GO:0031110) 101 0 .03 - < 0.01 1.00E00 1.00E00 thiamine diphosphate biosynthetic process (GO:0009229) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-sugar catabolic process (GO:0009227) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-sugar biosynthetic process (GO:0009226) 29 0 .01 - < 0.01 1.00E00 1.00E00 nucleotide-sugar metabolic process (GO:0009225) 44 0 .01 - < 0.01 1.00E00 1.00E00 CMP biosynthetic process (GO:0009224) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleotide catabolic process (GO:0009223) 18 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide catabolic process (GO:0009222) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleotide biosynthetic process (GO:0009221) 7 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide biosynthetic process (GO:0009220) 25 0 .01 - < 0.01 1.00E00 1.00E00 microtubule polymerization or depolymerization (GO:0031109) 63 0 .02 - < 0.01 1.00E00 1.00E00 septin ring organization (GO:0031106) 2 0 .00 - < 0.01 1.00E00 1.00E00 dendrite regeneration (GO:0031104) 2 0 .00 - < 0.01 1.00E00 1.00E00 axon regeneration (GO:0031103) 23 0 .01 - < 0.01 1.00E00 1.00E00 neuron projection regeneration (GO:0031102) 30 0 .01 - < 0.01 1.00E00 1.00E00 animal organ regeneration (GO:0031100) 65 0 .02 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleotide metabolic process (GO:0009219) 24 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleotide metabolic process (GO:0009218) 33 0 .01 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside triphosphate catabolic process (GO:0009217) 4 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside triphosphate biosynthetic process (GO:0009216) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) 7 0 .00 - < 0.01 1.00E00 1.00E00 cyclic nucleotide catabolic process (GO:0009214) 14 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate catabolic process (GO:0009213) 2 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate biosynthetic process (GO:0009212) 4 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside triphosphate metabolic process (GO:0009211) 6 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate catabolic process (GO:0009210) 1 0 .00 - < 0.01 1.00E00 1.00E00 follicle-stimulating hormone signaling pathway (GO:0042699) 3 0 .00 - < 0.01 1.00E00 1.00E00 ovulation cycle (GO:0042698) 72 0 .02 - < 0.01 1.00E00 1.00E00 thelarche (GO:0042695) 5 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell fate specification (GO:0042694) 1 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell fate commitment (GO:0042693) 16 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell differentiation (GO:0042692) 282 0 .08 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) 15 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) 18 0 .01 - < 0.01 1.00E00 1.00E00 purine ribonucleoside triphosphate catabolic process (GO:0009207) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside triphosphate biosynthetic process (GO:0009206) 95 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of connective tissue replacement involved in inflammatory response wound healing (GO:1904597) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside triphosphate metabolic process (GO:0009205) 191 0 .06 - < 0.01 1.00E00 1.00E00 regulation of connective tissue replacement involved in inflammatory response wound healing (GO:1904596) 2 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate catabolic process (GO:0009204) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of termination of RNA polymerase II transcription (GO:1904595) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside triphosphate catabolic process (GO:0009203) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of termination of RNA polymerase II transcription (GO:1904594) 4 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate biosynthetic process (GO:0009202) 1 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside triphosphate biosynthetic process (GO:0009201) 101 0 .03 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside triphosphate metabolic process (GO:0009200) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein import (GO:1904591) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein import (GO:1904589) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glycoprotein (GO:1904588) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to glycoprotein (GO:1904587) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to putrescine (GO:1904586) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to putrescine (GO:1904585) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to polyamine macromolecule (GO:1904583) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intracellular mRNA localization (GO:1904582) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intracellular mRNA localization (GO:1904580) 5 0 .00 - < 0.01 1.00E00 1.00E00 retinal cone cell differentiation (GO:0042670) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of selenocysteine incorporation (GO:1904570) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inner ear auditory receptor cell fate specification (GO:0042669) 1 0 .00 - < 0.01 1.00E00 1.00E00 auditory receptor cell fate determination (GO:0042668) 1 0 .00 - < 0.01 1.00E00 1.00E00 auditory receptor cell fate specification (GO:0042667) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ectodermal cell fate specification (GO:0042666) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ectodermal cell fate specification (GO:0042665) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endodermal cell fate specification (GO:0042664) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endodermal cell fate specification (GO:0042663) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesodermal cell fate specification (GO:0042662) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesodermal cell fate specification (GO:0042661) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell fate specification (GO:0042660) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of selenocysteine incorporation (GO:1904569) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to postsynapse (GO:0062237) 32 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to wortmannin (GO:1904568) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to wortmannin (GO:1904567) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to 1-oleoyl-sn-glycerol 3-phosphate (GO:1904566) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to 1-oleoyl-sn-glycerol 3-phosphate (GO:1904565) 2 0 .00 - < 0.01 1.00E00 1.00E00 platelet activating factor catabolic process (GO:0062234) 2 0 .00 - < 0.01 1.00E00 1.00E00 prostanoid catabolic process (GO:0062232) 2 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylinositol 5-phosphate metabolic process (GO:1904562) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell fate specification (GO:0042659) 24 0 .01 - < 0.01 1.00E00 1.00E00 L-alanine transmembrane transport (GO:1904557) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-tryptophan transmembrane transport (GO:1904556) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-proline transmembrane transport (GO:1904555) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to arachidonate (GO:1904551) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to arachidonate (GO:1904550) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oocyte maturation (GO:1900195) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oocyte maturation (GO:1900194) 4 0 .00 - < 0.01 1.00E00 1.00E00 membrane bending (GO:0097753) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oocyte maturation (GO:1900193) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA stability (GO:0097752) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of single-species biofilm formation (GO:1900191) 2 0 .00 - < 0.01 1.00E00 1.00E00 endosome membrane tubulation (GO:0097750) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of single-species biofilm formation (GO:1900190) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of free ubiquitin chain polymerization (GO:1904544) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of free ubiquitin chain polymerization (GO:1904542) 2 0 .00 - < 0.01 1.00E00 1.00E00 membrane tubulation (GO:0097749) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glycolytic process through fructose-6-phosphate (GO:1904540) 1 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel diameter maintenance (GO:0097746) 158 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of clathrin-dependent endocytosis (GO:1900186) 4 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial tRNA 5'-end processing (GO:0097745) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal urate salt excretion (GO:0097744) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hair cycle (GO:0042636) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hair cycle (GO:0042635) 2 0 .00 - < 0.01 1.00E00 1.00E00 de novo centriole assembly (GO:0097742) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hair cycle (GO:0042634) 29 0 .01 - < 0.01 1.00E00 1.00E00 hair cycle (GO:0042633) 100 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to nucleus (GO:1900182) 94 0 .03 - < 0.01 1.00E00 1.00E00 cholesterol homeostasis (GO:0042632) 97 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to nucleus (GO:1900181) 40 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to water deprivation (GO:0042631) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to nucleus (GO:1900180) 148 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of pattern recognition receptor signaling pathway (GO:0062208) 79 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of glycolytic process through fructose-6-phosphate (GO:1904539) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pattern recognition receptor signaling pathway (GO:0062207) 185 0 .05 - < 0.01 1.00E00 1.00E00 regulation of glycolytic process through fructose-6-phosphate (GO:1904538) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomeric loop disassembly (GO:1904535) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomeric loop disassembly (GO:1904534) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomeric loop disassembly (GO:1904533) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament binding (GO:1904531) 1 0 .00 - < 0.01 1.00E00 1.00E00 mating plug formation (GO:0042628) 1 0 .00 - < 0.01 1.00E00 1.00E00 extracellular exosome biogenesis (GO:0097734) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vitamin metabolic process (GO:0030656) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microtubule binding (GO:1904528) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microtubule binding (GO:1904527) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule binding (GO:1904526) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myofibroblast cell apoptotic process (GO:1904520) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell-derived neurotrophic factor production (GO:1900168) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glial cell-derived neurotrophic factor production (GO:1900166) 2 0 .00 - < 0.01 1.00E00 1.00E00 sperm motility (GO:0097722) 180 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid scramblase activity (GO:1900163) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcineurin-mediated signaling (GO:0097720) 25 0 .01 - < 0.01 1.00E00 1.00E00 aminoglycoside antibiotic metabolic process (GO:0030647) 10 0 .00 - < 0.01 1.00E00 1.00E00 intracellular chloride ion homeostasis (GO:0030644) 10 0 .00 - < 0.01 1.00E00 1.00E00 intracellular phosphate ion homeostasis (GO:0030643) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular pH (GO:0030641) 94 0 .03 - < 0.01 1.00E00 1.00E00 protein localization to cytoplasmic microtubule plus-end (GO:1904518) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of TORC2 signaling (GO:1904515) 8 0 .00 - < 0.01 1.00E00 1.00E00 neural tissue regeneration (GO:0097719) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to basolateral plasma membrane (GO:1904510) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of bone mineralization involved in bone maturation (GO:1900159) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bone mineralization involved in bone maturation (GO:1900158) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bone mineralization involved in bone maturation (GO:1900157) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bone trabecula formation (GO:1900155) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bone trabecula formation (GO:1900154) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900153) 12 0 .00 - < 0.01 1.00E00 1.00E00 vesicle targeting, trans-Golgi to periciliary membrane compartment (GO:0097712) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900152) 12 0 .00 - < 0.01 1.00E00 1.00E00 ciliary basal body-plasma membrane docking (GO:0097711) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of defense response to fungus (GO:1900150) 7 0 .00 - < 0.01 1.00E00 1.00E00 polyketide metabolic process (GO:0030638) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to basolateral plasma membrane (GO:1904508) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance in response to DNA damage (GO:1904507) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance in response to DNA damage (GO:1904506) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance in response to DNA damage (GO:1904505) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lipophagy (GO:1904504) 5 0 .00 - < 0.01 1.00E00 1.00E00 dendrite development (GO:0016358) 116 0 .03 - < 0.01 1.00E00 1.00E00 regulation of lipophagy (GO:1904502) 5 0 .00 - < 0.01 1.00E00 1.00E00 connective tissue replacement (GO:0097709) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell migration (GO:1900149) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Schwann cell migration (GO:1900148) 3 0 .00 - < 0.01 1.00E00 1.00E00 ferroptosis (GO:0097707) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell migration (GO:1900147) 5 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial cell response to oscillatory fluid shear stress (GO:0097706) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oscillatory fluid shear stress (GO:0097704) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to oscillatory fluid shear stress (GO:0097702) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oligodendrocyte apoptotic process (GO:1900143) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oligodendrocyte apoptotic process (GO:1900142) 1 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial cell response to laminar fluid shear stress (GO:0097700) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of oligodendrocyte apoptotic process (GO:1900141) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of arachidonate secretion (GO:1900139) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase A2 activity (GO:1900138) 2 0 .00 - < 0.01 1.00E00 1.00E00 Golgi lumen acidification (GO:0061795) 10 0 .00 - < 0.01 1.00E00 1.00E00 meiotic chromosome movement towards spindle pole (GO:0016344) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of renin secretion into blood stream (GO:1900135) 2 0 .00 - < 0.01 1.00E00 1.00E00 secretory granule maturation (GO:0061792) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of renin secretion into blood stream (GO:1900134) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renin secretion into blood stream (GO:1900133) 3 0 .00 - < 0.01 1.00E00 1.00E00 calcium-dependent cell-matrix adhesion (GO:0016340) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipid binding (GO:1900131) 1 0 .00 - < 0.01 1.00E00 1.00E00 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339) 46 0 .01 - < 0.01 1.00E00 1.00E00 dense core granule priming (GO:0061789) 3 0 .00 - < 0.01 1.00E00 1.00E00 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) 21 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of polarity of follicular epithelium (GO:0016334) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hyaluronan biosynthetic process (GO:1900127) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hyaluronan biosynthetic process (GO:1900126) 4 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of follicular epithelium (GO:0016333) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hyaluronan biosynthetic process (GO:1900125) 8 0 .00 - < 0.01 1.00E00 1.00E00 establishment or maintenance of polarity of embryonic epithelium (GO:0016332) 2 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of embryonic epithelium (GO:0016331) 143 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of receptor binding (GO:1900122) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor binding (GO:1900121) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of receptor binding (GO:1900120) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of execution phase of apoptosis (GO:1900119) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of execution phase of apoptosis (GO:1900118) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of execution phase of apoptosis (GO:1900117) 34 0 .01 - < 0.01 1.00E00 1.00E00 extracellular negative regulation of signal transduction (GO:1900116) 12 0 .00 - < 0.01 1.00E00 1.00E00 neuron remodeling (GO:0016322) 14 0 .00 - < 0.01 1.00E00 1.00E00 extracellular regulation of signal transduction (GO:1900115) 12 0 .00 - < 0.01 1.00E00 1.00E00 female meiosis chromosome segregation (GO:0016321) 6 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic transport across blood-nerve barrier (GO:0061772) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to caloric restriction (GO:0061771) 4 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum membrane fusion (GO:0016320) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrion transport along microtubule (GO:0047497) 25 0 .01 - < 0.01 1.00E00 1.00E00 vesicle transport along microtubule (GO:0047496) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lung blood pressure (GO:0061767) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nodal signaling pathway (GO:1900108) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nodal signaling pathway (GO:1900107) 6 0 .00 - < 0.01 1.00E00 1.00E00 late endosome to lysosome transport via multivesicular body sorting pathway (GO:0061764) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hyaluranon cable assembly (GO:1900106) 3 0 .00 - < 0.01 1.00E00 1.00E00 multivesicular body-lysosome fusion (GO:0061763) 12 0 .00 - < 0.01 1.00E00 1.00E00 dephosphorylation (GO:0016311) 144 0 .04 - < 0.01 1.00E00 1.00E00 regulation of hyaluranon cable assembly (GO:1900104) 3 0 .00 - < 0.01 1.00E00 1.00E00 CAMKK-AMPK signaling cascade (GO:0061762) 6 0 .00 - < 0.01 1.00E00 1.00E00 phosphorylation (GO:0016310) 423 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum unfolded protein response (GO:1900103) 13 0 .00 - < 0.01 1.00E00 1.00E00 antifungal innate immune response (GO:0061760) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum unfolded protein response (GO:1900102) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum unfolded protein response (GO:1900101) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of plasma cell differentiation (GO:1900100) 4 0 .00 - < 0.01 1.00E00 1.00E00 low-density lipoprotein particle mediated signaling (GO:0055096) 4 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein particle mediated signaling (GO:0055095) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to lipoprotein particle (GO:0055094) 31 0 .01 - < 0.01 1.00E00 1.00E00 response to hyperoxia (GO:0055093) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of response to osmotic stress (GO:0047484) 15 0 .00 - < 0.01 1.00E00 1.00E00 sterol homeostasis (GO:0055092) 98 0 .03 - < 0.01 1.00E00 1.00E00 phospholipid homeostasis (GO:0055091) 17 0 .00 - < 0.01 1.00E00 1.00E00 acylglycerol homeostasis (GO:0055090) 43 0 .01 - < 0.01 1.00E00 1.00E00 leukocyte adhesion to arterial endothelial cell (GO:0061757) 1 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte adhesion to vascular endothelial cell (GO:0061756) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of circulating fibrinogen levels (GO:0061755) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by action potential (GO:0100001) 1 0 .00 - < 0.01 1.00E00 1.00E00 substrate localization to autophagosome (GO:0061753) 4 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid homeostasis (GO:0055089) 17 0 .00 - < 0.01 1.00E00 1.00E00 lipid homeostasis (GO:0055088) 174 0 .05 - < 0.01 1.00E00 1.00E00 nucleobase-containing small molecule metabolic process (GO:0055086) 611 0 .18 - < 0.01 1.00E00 1.00E00 transmembrane transport (GO:0055085) 1293 0 .38 - < 0.01 1.00E00 1.00E00 intracellular chemical homeostasis (GO:0055082) 578 0 .17 - < 0.01 1.00E00 1.00E00 monoatomic anion homeostasis (GO:0055081) 21 0 .01 - < 0.01 1.00E00 1.00E00 monoatomic cation homeostasis (GO:0055080) 512 0 .15 - < 0.01 1.00E00 1.00E00 motor behavior (GO:0061744) 31 0 .01 - < 0.01 1.00E00 1.00E00 motor learning (GO:0061743) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein targeting to lysosome involved in chaperone-mediated autophagy (GO:0061740) 3 0 .00 - < 0.01 1.00E00 1.00E00 sodium ion homeostasis (GO:0055078) 39 0 .01 - < 0.01 1.00E00 1.00E00 potassium ion homeostasis (GO:0055075) 36 0 .01 - < 0.01 1.00E00 1.00E00 calcium ion homeostasis (GO:0055074) 230 0 .07 - < 0.01 1.00E00 1.00E00 manganese ion homeostasis (GO:0055071) 4 0 .00 - < 0.01 1.00E00 1.00E00 copper ion homeostasis (GO:0055070) 21 0 .01 - < 0.01 1.00E00 1.00E00 carnosine biosynthetic process (GO:0035499) 1 0 .00 - < 0.01 1.00E00 1.00E00 carnosine metabolic process (GO:0035498) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein lipidation involved in autophagosome assembly (GO:0061739) 1 0 .00 - < 0.01 1.00E00 1.00E00 late endosomal microautophagy (GO:0061738) 2 0 .00 - < 0.01 1.00E00 1.00E00 SNARE complex disassembly (GO:0035494) 3 0 .00 - < 0.01 1.00E00 1.00E00 leukotriene signaling pathway (GO:0061737) 5 0 .00 - < 0.01 1.00E00 1.00E00 SNARE complex assembly (GO:0035493) 12 0 .00 - < 0.01 1.00E00 1.00E00 engulfment of target by autophagosome (GO:0061736) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of leukotriene production involved in inflammatory response (GO:0035491) 1 0 .00 - < 0.01 1.00E00 1.00E00 type 2 mitophagy (GO:0061734) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of leukotriene production involved in inflammatory response (GO:0035490) 1 0 .00 - < 0.01 1.00E00 1.00E00 chloride ion homeostasis (GO:0055064) 19 0 .01 - < 0.01 1.00E00 1.00E00 phosphate ion homeostasis (GO:0055062) 20 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside salvage (GO:0043097) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase salvage (GO:0043096) 3 0 .00 - < 0.01 1.00E00 1.00E00 metabolic compound salvage (GO:0043094) 44 0 .01 - < 0.01 1.00E00 1.00E00 GDP-D-mannose biosynthetic process from fructose-6-phosphate (GO:0061729) 2 0 .00 - < 0.01 1.00E00 1.00E00 GDP-mannose biosynthetic process from mannose (GO:0061728) 3 0 .00 - < 0.01 1.00E00 1.00E00 methylglyoxal catabolic process to lactate (GO:0061727) 4 0 .00 - < 0.01 1.00E00 1.00E00 gastric emptying (GO:0035483) 2 0 .00 - < 0.01 1.00E00 1.00E00 gastric motility (GO:0035482) 2 0 .00 - < 0.01 1.00E00 1.00E00 amino acid import (GO:0043090) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipophagy (GO:0061724) 3 0 .00 - < 0.01 1.00E00 1.00E00 glycophagy (GO:0061723) 12 0 .00 - < 0.01 1.00E00 1.00E00 asymmetric neuroblast division (GO:0055059) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast division (GO:0055057) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of GTPase activity (GO:0043087) 165 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of catalytic activity (GO:0043086) 245 0 .07 - < 0.01 1.00E00 1.00E00 positive regulation of catalytic activity (GO:0043085) 456 0 .13 - < 0.01 1.00E00 1.00E00 penile erection (GO:0043084) 2 0 .00 - < 0.01 1.00E00 1.00E00 glucose catabolic process to pyruvate (GO:0061718) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of vascular wound healing (GO:0035470) 6 0 .00 - < 0.01 1.00E00 1.00E00 anterior neural tube closure (GO:0061713) 3 0 .00 - < 0.01 1.00E00 1.00E00 siderophore transport (GO:0015891) 3 0 .00 - < 0.01 1.00E00 1.00E00 anastral spindle assembly (GO:0055048) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of pancreatic left/right asymmetry (GO:0035469) 5 0 .00 - < 0.01 1.00E00 1.00E00 reticulophagy (GO:0061709) 21 0 .01 - < 0.01 1.00E00 1.00E00 vitamin transmembrane transport (GO:0035461) 20 0 .01 - < 0.01 1.00E00 1.00E00 cobalamin transport (GO:0015889) 9 0 .00 - < 0.01 1.00E00 1.00E00 thiamine transport (GO:0015888) 8 0 .00 - < 0.01 1.00E00 1.00E00 pantothenate transmembrane transport (GO:0015887) 1 0 .00 - < 0.01 1.00E00 1.00E00 heme transport (GO:0015886) 9 0 .00 - < 0.01 1.00E00 1.00E00 folic acid transport (GO:0015884) 9 0 .00 - < 0.01 1.00E00 1.00E00 FAD transport (GO:0015883) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-ascorbic acid transmembrane transport (GO:0015882) 3 0 .00 - < 0.01 1.00E00 1.00E00 creatine transmembrane transport (GO:0015881) 4 0 .00 - < 0.01 1.00E00 1.00E00 coenzyme A transport (GO:0015880) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of programmed cell death (GO:0043069) 921 0 .27 - < 0.01 1.00E00 1.00E00 positive regulation of programmed cell death (GO:0043068) 549 0 .16 - < 0.01 1.00E00 1.00E00 vesicle cargo loading (GO:0035459) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of programmed cell death (GO:0043067) 1518 0 .44 - < 0.01 1.00E00 1.00E00 cellular response to interferon-beta (GO:0035458) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of apoptotic process (GO:0043066) 892 0 .26 - < 0.01 1.00E00 1.00E00 cellular response to interferon-alpha (GO:0035457) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of apoptotic process (GO:0043065) 534 0 .16 - < 0.01 1.00E00 1.00E00 response to interferon-beta (GO:0035456) 35 0 .01 - < 0.01 1.00E00 1.00E00 response to interferon-alpha (GO:0035455) 20 0 .01 - < 0.01 1.00E00 1.00E00 intercellular bridge organization (GO:0043063) 1 0 .00 - < 0.01 1.00E00 1.00E00 extracellular structure organization (GO:0043062) 282 0 .08 - < 0.01 1.00E00 1.00E00 meiotic metaphase I homologous chromosome alignment (GO:0043060) 4 0 .00 - < 0.01 1.00E00 1.00E00 regeneration (GO:0031099) 158 0 .05 - < 0.01 1.00E00 1.00E00 stress-activated protein kinase signaling cascade (GO:0031098) 27 0 .01 - < 0.01 1.00E00 1.00E00 carnitine transport (GO:0015879) 8 0 .00 - < 0.01 1.00E00 1.00E00 biotin transport (GO:0015878) 3 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA transport (GO:0015876) 2 0 .00 - < 0.01 1.00E00 1.00E00 norepinephrine transport (GO:0015874) 9 0 .00 - < 0.01 1.00E00 1.00E00 dopamine transport (GO:0015872) 21 0 .01 - < 0.01 1.00E00 1.00E00 choline transport (GO:0015871) 11 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine transport (GO:0015870) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle tissue development (GO:0055026) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle tissue development (GO:0055025) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle tissue development (GO:0055024) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle tissue growth (GO:0055023) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle tissue growth (GO:0055022) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle tissue growth (GO:0055021) 53 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle fiber development (GO:0055020) 1 0 .00 - < 0.01 1.00E00 1.00E00 borate transmembrane transport (GO:0035445) 1 0 .00 - < 0.01 1.00E00 1.00E00 nickel cation transmembrane transport (GO:0035444) 1 0 .00 - < 0.01 1.00E00 1.00E00 thermotaxis (GO:0043052) 2 0 .00 - < 0.01 1.00E00 1.00E00 tripeptide transmembrane transport (GO:0035443) 10 0 .00 - < 0.01 1.00E00 1.00E00 dipeptide transmembrane transport (GO:0035442) 6 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in vasculogenesis (GO:0035441) 4 0 .00 - < 0.01 1.00E00 1.00E00 deadenylation-independent decapping of nuclear-transcribed mRNA (GO:0031087) 5 0 .00 - < 0.01 1.00E00 1.00E00 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay (GO:0031086) 7 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleotide transport (GO:0015868) 36 0 .01 - < 0.01 1.00E00 1.00E00 ATP transport (GO:0015867) 24 0 .01 - < 0.01 1.00E00 1.00E00 ADP transport (GO:0015866) 12 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleotide transport (GO:0015865) 42 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside transport (GO:0015864) 6 0 .00 - < 0.01 1.00E00 1.00E00 uridine transmembrane transport (GO:0015862) 6 0 .00 - < 0.01 1.00E00 1.00E00 cytidine transport (GO:0015861) 4 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside transmembrane transport (GO:0015860) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle fiber development (GO:0055018) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue growth (GO:0055017) 34 0 .01 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle cell development (GO:0055015) 10 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell development (GO:0055014) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell development (GO:0055013) 62 0 .02 - < 0.01 1.00E00 1.00E00 ribonucleoside triphosphate metabolic process (GO:0009199) 198 0 .06 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle cell differentiation (GO:0055012) 15 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell differentiation (GO:0055011) 3 0 .00 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle tissue morphogenesis (GO:0055010) 47 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside diphosphate biosynthetic process (GO:0009197) 2 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside diphosphate metabolic process (GO:0009196) 2 0 .00 - < 0.01 1.00E00 1.00E00 otic placode formation (GO:0043049) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside diphosphate catabolic process (GO:0009195) 3 0 .00 - < 0.01 1.00E00 1.00E00 dolichyl monophosphate biosynthetic process (GO:0043048) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside diphosphate biosynthetic process (GO:0009194) 5 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein localization in endoplasmic reticulum (GO:0035437) 13 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside diphosphate metabolic process (GO:0009193) 8 0 .00 - < 0.01 1.00E00 1.00E00 epigenetic programming of gene expression (GO:0043045) 34 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside diphosphate catabolic process (GO:0009192) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphate ion transmembrane transport (GO:0035435) 12 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside diphosphate catabolic process (GO:0009191) 56 0 .02 - < 0.01 1.00E00 1.00E00 peptide biosynthetic process (GO:0043043) 25 0 .01 - < 0.01 1.00E00 1.00E00 copper ion transmembrane transport (GO:0035434) 8 0 .00 - < 0.01 1.00E00 1.00E00 cyclic nucleotide biosynthetic process (GO:0009190) 22 0 .01 - < 0.01 1.00E00 1.00E00 amino acid activation for nonribosomal peptide biosynthetic process (GO:0043041) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic camera-type eye development (GO:0031077) 8 0 .00 - < 0.01 1.00E00 1.00E00 embryonic camera-type eye development (GO:0031076) 37 0 .01 - < 0.01 1.00E00 1.00E00 nucleoside transport (GO:0015858) 8 0 .00 - < 0.01 1.00E00 1.00E00 uracil transport (GO:0015857) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase transport (GO:0015855) 7 0 .00 - < 0.01 1.00E00 1.00E00 guanine transport (GO:0015854) 4 0 .00 - < 0.01 1.00E00 1.00E00 adenine transport (GO:0015853) 6 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase transport (GO:0015851) 13 0 .00 - < 0.01 1.00E00 1.00E00 organic hydroxy compound transport (GO:0015850) 174 0 .05 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle tissue morphogenesis (GO:0055009) 6 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue morphogenesis (GO:0055008) 59 0 .02 - < 0.01 1.00E00 1.00E00 cardiac muscle cell differentiation (GO:0055007) 90 0 .03 - < 0.01 1.00E00 1.00E00 cardiac cell development (GO:0055006) 68 0 .02 - < 0.01 1.00E00 1.00E00 ventricular cardiac myofibril assembly (GO:0055005) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac myofibril assembly (GO:0055003) 18 0 .01 - < 0.01 1.00E00 1.00E00 striated muscle cell development (GO:0055002) 141 0 .04 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside diphosphate biosynthetic process (GO:0009189) 4 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell development (GO:0055001) 170 0 .05 - < 0.01 1.00E00 1.00E00 ribonucleoside diphosphate biosynthetic process (GO:0009188) 12 0 .00 - < 0.01 1.00E00 1.00E00 cyclic nucleotide metabolic process (GO:0009187) 42 0 .01 - < 0.01 1.00E00 1.00E00 tRNA aminoacylation (GO:0043039) 44 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside diphosphate metabolic process (GO:0009186) 5 0 .00 - < 0.01 1.00E00 1.00E00 amino acid activation (GO:0043038) 45 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleoside diphosphate metabolic process (GO:0009185) 80 0 .02 - < 0.01 1.00E00 1.00E00 gluconate transmembrane transport (GO:0035429) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate catabolic process (GO:0009184) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate biosynthetic process (GO:0009183) 2 0 .00 - < 0.01 1.00E00 1.00E00 extracellular matrix-cell signaling (GO:0035426) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside diphosphate metabolic process (GO:0009182) 3 0 .00 - < 0.01 1.00E00 1.00E00 autocrine signaling (GO:0035425) 7 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside diphosphate catabolic process (GO:0009181) 53 0 .02 - < 0.01 1.00E00 1.00E00 purine ribonucleoside diphosphate biosynthetic process (GO:0009180) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage activation (GO:0043032) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage activation (GO:0043031) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macrophage activation (GO:0043030) 59 0 .02 - < 0.01 1.00E00 1.00E00 hair follicle morphogenesis (GO:0031069) 34 0 .01 - < 0.01 1.00E00 1.00E00 organic acid transport (GO:0015849) 306 0 .09 - < 0.01 1.00E00 1.00E00 spermidine transport (GO:0015848) 5 0 .00 - < 0.01 1.00E00 1.00E00 putrescine transport (GO:0015847) 4 0 .00 - < 0.01 1.00E00 1.00E00 polyamine transport (GO:0015846) 11 0 .00 - < 0.01 1.00E00 1.00E00 monoamine transport (GO:0015844) 29 0 .01 - < 0.01 1.00E00 1.00E00 methylammonium transport (GO:0015843) 2 0 .00 - < 0.01 1.00E00 1.00E00 aminergic neurotransmitter loading into synaptic vesicle (GO:0015842) 3 0 .00 - < 0.01 1.00E00 1.00E00 urea transport (GO:0015840) 9 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside diphosphate metabolic process (GO:0009179) 69 0 .02 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate catabolic process (GO:0009178) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate biosynthetic process (GO:0009177) 4 0 .00 - < 0.01 1.00E00 1.00E00 T cell homeostasis (GO:0043029) 45 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine deoxyribonucleoside monophosphate metabolic process (GO:0009176) 12 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate catabolic process (GO:0009175) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to synapse (GO:0035418) 60 0 .02 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) 12 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) 16 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside monophosphate catabolic process (GO:0009172) 6 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside monophosphate biosynthetic process (GO:0009171) 3 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleoside monophosphate metabolic process (GO:0009170) 11 0 .00 - < 0.01 1.00E00 1.00E00 amino-acid betaine transport (GO:0015838) 13 0 .00 - < 0.01 1.00E00 1.00E00 chromatin remodeling at centromere (GO:0031055) 10 0 .00 - < 0.01 1.00E00 1.00E00 amine transport (GO:0015837) 13 0 .00 - < 0.01 1.00E00 1.00E00 pre-miRNA processing (GO:0031054) 14 0 .00 - < 0.01 1.00E00 1.00E00 primary miRNA processing (GO:0031053) 13 0 .00 - < 0.01 1.00E00 1.00E00 peptidoglycan transport (GO:0015835) 3 0 .00 - < 0.01 1.00E00 1.00E00 peptide transport (GO:0015833) 101 0 .03 - < 0.01 1.00E00 1.00E00 purine ribonucleoside monophosphate catabolic process (GO:0009169) 10 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleoside monophosphate biosynthetic process (GO:0009168) 19 0 .01 - < 0.01 1.00E00 1.00E00 purine ribonucleoside monophosphate metabolic process (GO:0009167) 41 0 .01 - < 0.01 1.00E00 1.00E00 nucleotide catabolic process (GO:0009166) 113 0 .03 - < 0.01 1.00E00 1.00E00 nucleotide biosynthetic process (GO:0009165) 216 0 .06 - < 0.01 1.00E00 1.00E00 nucleoside catabolic process (GO:0009164) 19 0 .01 - < 0.01 1.00E00 1.00E00 nucleoside biosynthetic process (GO:0009163) 19 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside monophosphate metabolic process (GO:0009162) 25 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleoside monophosphate metabolic process (GO:0009161) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of fusion of sperm to egg plasma membrane (GO:0043012) 1 0 .00 - < 0.01 1.00E00 1.00E00 myeloid dendritic cell differentiation (GO:0043011) 20 0 .01 - < 0.01 1.00E00 1.00E00 camera-type eye development (GO:0043010) 357 0 .10 - < 0.01 1.00E00 1.00E00 regulatory ncRNA-mediated heterochromatin formation (GO:0031048) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulatory ncRNA-mediated gene silencing (GO:0031047) 113 0 .03 - < 0.01 1.00E00 1.00E00 valine transport (GO:0015829) 4 0 .00 - < 0.01 1.00E00 1.00E00 tyrosine transport (GO:0015828) 3 0 .00 - < 0.01 1.00E00 1.00E00 tryptophan transport (GO:0015827) 6 0 .00 - < 0.01 1.00E00 1.00E00 threonine transport (GO:0015826) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-serine transport (GO:0015825) 9 0 .00 - < 0.01 1.00E00 1.00E00 proline transport (GO:0015824) 11 0 .00 - < 0.01 1.00E00 1.00E00 phenylalanine transport (GO:0015823) 4 0 .00 - < 0.01 1.00E00 1.00E00 ornithine transport (GO:0015822) 7 0 .00 - < 0.01 1.00E00 1.00E00 methionine transport (GO:0015821) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-leucine transport (GO:0015820) 10 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside monophosphate catabolic process (GO:0009159) 14 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside monophosphate catabolic process (GO:0009158) 14 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside monophosphate biosynthetic process (GO:0009157) 9 0 .00 - < 0.01 1.00E00 1.00E00 chordate embryonic development (GO:0043009) 660 1 .19 + 5.20 1.78E-01 1.00E00 ribonucleoside monophosphate biosynthetic process (GO:0009156) 35 0 .01 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleotide catabolic process (GO:0009155) 10 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleotide catabolic process (GO:0009154) 81 0 .02 - < 0.01 1.00E00 1.00E00 maintenance of rDNA (GO:0043007) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleotide biosynthetic process (GO:0009153) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleotide biosynthetic process (GO:0009152) 143 0 .04 - < 0.01 1.00E00 1.00E00 purine deoxyribonucleotide metabolic process (GO:0009151) 16 0 .00 - < 0.01 1.00E00 1.00E00 purine ribonucleotide metabolic process (GO:0009150) 287 0 .08 - < 0.01 1.00E00 1.00E00 Golgi to plasma membrane protein transport (GO:0043001) 32 0 .01 - < 0.01 1.00E00 1.00E00 myosin II filament organization (GO:0031038) 1 0 .00 - < 0.01 1.00E00 1.00E00 lysine transport (GO:0015819) 2 0 .00 - < 0.01 1.00E00 1.00E00 myosin II filament disassembly (GO:0031037) 1 0 .00 - < 0.01 1.00E00 1.00E00 isoleucine transport (GO:0015818) 5 0 .00 - < 0.01 1.00E00 1.00E00 histidine transport (GO:0015817) 4 0 .00 - < 0.01 1.00E00 1.00E00 myosin filament disassembly (GO:0031035) 1 0 .00 - < 0.01 1.00E00 1.00E00 myosin filament assembly (GO:0031034) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycine transport (GO:0015816) 15 0 .00 - < 0.01 1.00E00 1.00E00 myosin filament organization (GO:0031033) 5 0 .00 - < 0.01 1.00E00 1.00E00 actomyosin structure organization (GO:0031032) 123 0 .04 - < 0.01 1.00E00 1.00E00 L-glutamate transmembrane transport (GO:0015813) 28 0 .01 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid transport (GO:0015812) 15 0 .00 - < 0.01 1.00E00 1.00E00 L-cystine transport (GO:0015811) 6 0 .00 - < 0.01 1.00E00 1.00E00 aspartate transmembrane transport (GO:0015810) 20 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside triphosphate catabolic process (GO:0009149) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) 19 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside triphosphate metabolic process (GO:0009147) 24 0 .01 - < 0.01 1.00E00 1.00E00 purine nucleoside triphosphate catabolic process (GO:0009146) 5 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside triphosphate biosynthetic process (GO:0009145) 96 0 .03 - < 0.01 1.00E00 1.00E00 purine nucleoside triphosphate metabolic process (GO:0009144) 198 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of hemoglobin biosynthetic process (GO:0046986) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hemoglobin biosynthetic process (GO:0046985) 6 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside triphosphate catabolic process (GO:0009143) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hemoglobin biosynthetic process (GO:0046984) 8 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside triphosphate biosynthetic process (GO:0009142) 110 0 .03 - < 0.01 1.00E00 1.00E00 nucleoside triphosphate metabolic process (GO:0009141) 214 0 .06 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside diphosphate catabolic process (GO:0009140) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-alanine transport (GO:0015808) 11 0 .00 - < 0.01 1.00E00 1.00E00 L-amino acid transport (GO:0015807) 83 0 .02 - < 0.01 1.00E00 1.00E00 microtubule organizing center organization (GO:0031023) 111 0 .03 - < 0.01 1.00E00 1.00E00 S-adenosyl-L-methionine transport (GO:0015805) 1 0 .00 - < 0.01 1.00E00 1.00E00 neutral amino acid transport (GO:0015804) 53 0 .02 - < 0.01 1.00E00 1.00E00 nuclear migration along microfilament (GO:0031022) 2 0 .00 - < 0.01 1.00E00 1.00E00 branched-chain amino acid transport (GO:0015803) 14 0 .00 - < 0.01 1.00E00 1.00E00 basic amino acid transport (GO:0015802) 23 0 .01 - < 0.01 1.00E00 1.00E00 aromatic amino acid transport (GO:0015801) 13 0 .00 - < 0.01 1.00E00 1.00E00 acidic amino acid transport (GO:0015800) 51 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside diphosphate biosynthetic process (GO:0009139) 7 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside diphosphate metabolic process (GO:0009138) 10 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to chemical stress (GO:0062197) 282 0 .08 - < 0.01 1.00E00 1.00E00 purine nucleoside diphosphate catabolic process (GO:0009137) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of lysosome size (GO:0062196) 9 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside diphosphate biosynthetic process (GO:0009136) 7 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside diphosphate metabolic process (GO:0009135) 69 0 .02 - < 0.01 1.00E00 1.00E00 nucleoside diphosphate catabolic process (GO:0009134) 59 0 .02 - < 0.01 1.00E00 1.00E00 nucleoside diphosphate biosynthetic process (GO:0009133) 15 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside diphosphate metabolic process (GO:0009132) 86 0 .03 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate catabolic process (GO:0009131) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) 16 0 .00 - < 0.01 1.00E00 1.00E00 endocrine pancreas development (GO:0031018) 38 0 .01 - < 0.01 1.00E00 1.00E00 exocrine pancreas development (GO:0031017) 9 0 .00 - < 0.01 1.00E00 1.00E00 pancreas development (GO:0031016) 72 0 .02 - < 0.01 1.00E00 1.00E00 pyrimidine nucleoside monophosphate metabolic process (GO:0009129) 22 0 .01 - < 0.01 1.00E00 1.00E00 purine nucleoside monophosphate catabolic process (GO:0009128) 10 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside monophosphate biosynthetic process (GO:0009127) 21 0 .01 - < 0.01 1.00E00 1.00E00 purine nucleoside monophosphate metabolic process (GO:0009126) 43 0 .01 - < 0.01 1.00E00 1.00E00 peptide antigen transport (GO:0046968) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside monophosphate catabolic process (GO:0009125) 18 0 .01 - < 0.01 1.00E00 1.00E00 cytosol to endoplasmic reticulum transport (GO:0046967) 5 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside monophosphate biosynthetic process (GO:0009124) 43 0 .01 - < 0.01 1.00E00 1.00E00 nucleoside monophosphate metabolic process (GO:0009123) 78 0 .02 - < 0.01 1.00E00 1.00E00 3'-phosphoadenosine 5'-phosphosulfate transport (GO:0046963) 2 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribonucleoside metabolic process (GO:0009120) 11 0 .00 - < 0.01 1.00E00 1.00E00 sensitization (GO:0046960) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to caffeine (GO:0031000) 15 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside metabolic process (GO:0009119) 30 0 .01 - < 0.01 1.00E00 1.00E00 nucleotide metabolic process (GO:0009117) 438 0 .13 - < 0.01 1.00E00 1.00E00 habituation (GO:0046959) 4 0 .00 - < 0.01 1.00E00 1.00E00 radial spoke assembly (GO:0062177) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside metabolic process (GO:0009116) 60 0 .02 - < 0.01 1.00E00 1.00E00 R-loop processing (GO:0062176) 9 0 .00 - < 0.01 1.00E00 1.00E00 nonassociative learning (GO:0046958) 7 0 .00 - < 0.01 1.00E00 1.00E00 xanthine catabolic process (GO:0009115) 1 0 .00 - < 0.01 1.00E00 1.00E00 brexanolone catabolic process (GO:0062175) 1 0 .00 - < 0.01 1.00E00 1.00E00 hypoxanthine catabolic process (GO:0009114) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleobase biosynthetic process (GO:0009113) 9 0 .00 - < 0.01 1.00E00 1.00E00 brexanolone metabolic process (GO:0062173) 2 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase metabolic process (GO:0009112) 34 0 .01 - < 0.01 1.00E00 1.00E00 lutein catabolic process (GO:0062172) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin catabolic process (GO:0009111) 16 0 .00 - < 0.01 1.00E00 1.00E00 ketone body catabolic process (GO:0046952) 3 0 .00 - < 0.01 1.00E00 1.00E00 vitamin biosynthetic process (GO:0009110) 17 0 .00 - < 0.01 1.00E00 1.00E00 lutein metabolic process (GO:0062170) 1 0 .00 - < 0.01 1.00E00 1.00E00 ketone body biosynthetic process (GO:0046951) 6 0 .00 - < 0.01 1.00E00 1.00E00 fear response (GO:0042596) 39 0 .01 - < 0.01 1.00E00 1.00E00 behavioral response to starvation (GO:0042595) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to starvation (GO:0042594) 229 0 .07 - < 0.01 1.00E00 1.00E00 G protein-coupled receptor signaling pathway involved in heart process (GO:0086103) 6 0 .00 - < 0.01 1.00E00 1.00E00 glucose homeostasis (GO:0042593) 206 0 .06 - < 0.01 1.00E00 1.00E00 homeostatic process (GO:0042592) 1475 0 .43 - < 0.01 1.00E00 1.00E00 peptidyl-lysine deacetylation (GO:0034983) 5 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial protein processing (GO:0034982) 11 0 .00 - < 0.01 1.00E00 1.00E00 endothelin receptor signaling pathway involved in heart process (GO:0086101) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelin receptor signaling pathway (GO:0086100) 12 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) 9 0 .00 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA biosynthetic process (GO:0046949) 28 0 .01 - < 0.01 1.00E00 1.00E00 lipoate biosynthetic process (GO:0009107) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipoate metabolic process (GO:0009106) 1 0 .00 - < 0.01 1.00E00 1.00E00 hydroxylysine biosynthetic process (GO:0046947) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipopolysaccharide catabolic process (GO:0009104) 1 0 .00 - < 0.01 1.00E00 1.00E00 hydroxylysine metabolic process (GO:0046946) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycoprotein biosynthetic process (GO:0009101) 279 0 .08 - < 0.01 1.00E00 1.00E00 vascular endothelial cell response to fluid shear stress (GO:0097699) 14 0 .00 - < 0.01 1.00E00 1.00E00 carboxylic acid transport (GO:0046942) 305 0 .09 - < 0.01 1.00E00 1.00E00 glycoprotein metabolic process (GO:0009100) 346 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to ciliary transition zone (GO:1904491) 8 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance via base-excision repair (GO:0097698) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside monophosphate phosphorylation (GO:0046940) 12 0 .00 - < 0.01 1.00E00 1.00E00 cell surface receptor signaling pathway via STAT (GO:0097696) 76 0 .02 - < 0.01 1.00E00 1.00E00 establishment of protein-containing complex localization to telomere (GO:0097695) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of RNA localization to telomere (GO:0097694) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to endoplasmic reticulum stress (GO:0034976) 234 0 .07 - < 0.01 1.00E00 1.00E00 protein folding in endoplasmic reticulum (GO:0034975) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to tetrahydrofolate (GO:1904482) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to tetrahydrofolate (GO:1904481) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal absorption (GO:1904480) 4 0 .00 - < 0.01 1.00E00 1.00E00 pore complex assembly (GO:0046931) 19 0 .01 - < 0.01 1.00E00 1.00E00 glutamate receptor clustering (GO:0097688) 5 0 .00 - < 0.01 1.00E00 1.00E00 retinal metabolic process (GO:0042574) 18 0 .01 - < 0.01 1.00E00 1.00E00 retinoic acid metabolic process (GO:0042573) 31 0 .01 - < 0.01 1.00E00 1.00E00 double-strand break repair via alternative nonhomologous end joining (GO:0097681) 9 0 .00 - < 0.01 1.00E00 1.00E00 box H/ACA sno(s)RNA processing (GO:0034964) 2 0 .00 - < 0.01 1.00E00 1.00E00 retinol metabolic process (GO:0042572) 52 1 .02 + 65.96 1.51E-02 1.00E00 box C/D sno(s)RNA processing (GO:0034963) 3 0 .00 - < 0.01 1.00E00 1.00E00 double-strand break repair via classical nonhomologous end joining (GO:0097680) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transport across blood-brain barrier (GO:0150202) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transport across blood-brain barrier (GO:0150201) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transport across blood-brain barrier (GO:0150200) 1 0 .00 - < 0.01 1.00E00 1.00E00 detection of stimulus involved in sensory perception of pain (GO:0062149) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of intestinal absorption (GO:1904479) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neurotransmitter secretion (GO:0046929) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intestinal absorption (GO:1904478) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neurotransmitter secretion (GO:0046928) 85 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of endothelin production (GO:1904472) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelin production (GO:1904470) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelin maturation (GO:0034959) 1 0 .00 - < 0.01 1.00E00 1.00E00 pteridine-containing compound catabolic process (GO:0042560) 4 0 .00 - < 0.01 1.00E00 1.00E00 leukocyte chemotaxis (GO:0030595) 141 0 .04 - < 0.01 1.00E00 1.00E00 neutrophil chemotaxis (GO:0030593) 54 0 .02 - < 0.01 1.00E00 1.00E00 DNA ADP-ribosylation (GO:0030592) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of matrix metallopeptidase secretion (GO:1904466) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of matrix metallopeptidase secretion (GO:1904465) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of matrix metallopeptidase secretion (GO:1904464) 6 0 .00 - < 0.01 1.00E00 1.00E00 pteridine-containing compound biosynthetic process (GO:0042559) 13 0 .00 - < 0.01 1.00E00 1.00E00 pteridine-containing compound metabolic process (GO:0042558) 33 0 .01 - < 0.01 1.00E00 1.00E00 superoxide anion generation (GO:0042554) 26 0 .01 - < 0.01 1.00E00 1.00E00 myelination (GO:0042552) 131 0 .04 - < 0.01 1.00E00 1.00E00 neuron maturation (GO:0042551) 46 0 .01 - < 0.01 1.00E00 1.00E00 symbiont intracellular protein transport in host (GO:0030581) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuronal action potential (GO:1904457) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid primary amide metabolic process (GO:0062126) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial gene expression (GO:0062125) 35 0 .01 - < 0.01 1.00E00 1.00E00 intracellular transport (GO:0046907) 1197 0 .35 - < 0.01 1.00E00 1.00E00 negative regulation of neuronal action potential (GO:1904456) 1 0 .00 - < 0.01 1.00E00 1.00E00 secretion (GO:0046903) 552 0 .16 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial membrane permeability (GO:0046902) 55 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of aspartate secretion (GO:1904450) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of plasma cell differentiation (GO:1900099) 2 0 .00 - < 0.01 1.00E00 1.00E00 tetrahydrofolylpolyglutamate biosynthetic process (GO:0046901) 1 0 .00 - < 0.01 1.00E00 1.00E00 tetrahydrofolylpolyglutamate metabolic process (GO:0046900) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasma cell differentiation (GO:1900098) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to hydrogen peroxide (GO:0042542) 97 0 .03 - < 0.01 1.00E00 1.00E00 hemoglobin biosynthetic process (GO:0042541) 6 0 .00 - < 0.01 1.00E00 1.00E00 PML body organization (GO:0030578) 7 0 .00 - < 0.01 1.00E00 1.00E00 Cajal body organization (GO:0030576) 4 0 .00 - < 0.01 1.00E00 1.00E00 nuclear body organization (GO:0030575) 18 0 .01 - < 0.01 1.00E00 1.00E00 collagen catabolic process (GO:0030574) 41 0 .01 - < 0.01 1.00E00 1.00E00 bile acid catabolic process (GO:0030573) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aspartate secretion (GO:1904448) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of translational initiation by eIF2 alpha phosphorylation (GO:0010998) 2 0 .00 - < 0.01 1.00E00 1.00E00 folate import across plasma membrane (GO:1904447) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to auditory stimulus (GO:0010996) 33 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of Sertoli cell barrier (GO:1904445) 1 0 .00 - < 0.01 1.00E00 1.00E00 free ubiquitin chain polymerization (GO:0010994) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of Sertoli cell barrier (GO:1904444) 1 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid primary amide biosynthetic process (GO:0062112) 1 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin recycling (GO:0010992) 12 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into organelle (GO:0062111) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of thyroid gland epithelial cell proliferation (GO:1904442) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of thyroid gland epithelial cell proliferation (GO:1904441) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of iron ion import across plasma membrane (GO:1904440) 1 0 .00 - < 0.01 1.00E00 1.00E00 hypotonic salinity response (GO:0042539) 3 0 .00 - < 0.01 1.00E00 1.00E00 amylin receptor signaling pathway (GO:0097647) 6 0 .00 - < 0.01 1.00E00 1.00E00 calcitonin family receptor signaling pathway (GO:0097646) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of G1/S transition of mitotic cell cycle (GO:1900087) 44 0 .01 - < 0.01 1.00E00 1.00E00 hyperosmotic salinity response (GO:0042538) 5 0 .00 - < 0.01 1.00E00 1.00E00 benzene-containing compound metabolic process (GO:0042537) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-tyrosine autophosphorylation (GO:1900086) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-tyrosine autophosphorylation (GO:1900084) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of arginine catabolic process (GO:1900082) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-ornithine import across plasma membrane (GO:0097640) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tyrosine phosphorylation of STAT protein (GO:0042532) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of arginine catabolic process (GO:1900081) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tyrosine phosphorylation of STAT protein (GO:0042531) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of low-density lipoprotein particle clearance (GO:0010989) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion import across plasma membrane (GO:1904439) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of low-density lipoprotein particle clearance (GO:0010988) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of iron ion import across plasma membrane (GO:1904438) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transferrin receptor binding (GO:1904437) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of high-density lipoprotein particle clearance (GO:0010987) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipoprotein particle clearance (GO:0010986) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein particle clearance (GO:0010985) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein particle clearance (GO:0010984) 21 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of ferrous iron binding (GO:1904434) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of high-density lipoprotein particle clearance (GO:0010983) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of high-density lipoprotein particle clearance (GO:0010982) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of programmed necrotic cell death (GO:0062100) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine import across plasma membrane (GO:0097639) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of t-circle formation (GO:1904431) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-arginine import across plasma membrane (GO:0097638) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of t-circle formation (GO:1904430) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D 24-hydroxylase activity (GO:0010980) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of arginine biosynthetic process (GO:1900079) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to insulin stimulus (GO:1900078) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to insulin stimulus (GO:1900077) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cellular response to insulin stimulus (GO:1900076) 74 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of neuromuscular synaptic transmission (GO:1900075) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuromuscular synaptic transmission (GO:1900073) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of t-circle formation (GO:1904429) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tubulin deacetylation (GO:1904428) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron projection development (GO:0010977) 129 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transmembrane transport (GO:1904427) 81 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of neuron projection development (GO:0010976) 159 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of GTP binding (GO:1904426) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron projection development (GO:0010975) 440 0 .13 - < 0.01 1.00E00 1.00E00 negative regulation of G2/M transition of mitotic cell cycle (GO:0010972) 70 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of G2/M transition of mitotic cell cycle (GO:0010971) 28 0 .01 - < 0.01 1.00E00 1.00E00 response to D-galactosamine (GO:1904421) 1 0 .00 - < 0.01 1.00E00 1.00E00 transport along microtubule (GO:0010970) 174 0 .05 - < 0.01 1.00E00 1.00E00 regulation of cellular hyperosmotic salinity response (GO:1900069) 4 0 .00 - < 0.01 1.00E00 1.00E00 potassium ion export across plasma membrane (GO:0097623) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peroxisome organization (GO:1900063) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ceramide biosynthetic process (GO:1900060) 5 0 .00 - < 0.01 1.00E00 1.00E00 female genitalia development (GO:0030540) 19 1 .01 + > 100 5.53E-03 1.00E00 regulation of microtubule nucleation (GO:0010968) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of xenophagy (GO:1904417) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of polyamine biosynthetic process (GO:0010967) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphate transport (GO:0010966) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic sister chromatid separation (GO:0010965) 62 0 .02 - < 0.01 1.00E00 1.00E00 regulation of xenophagy (GO:1904415) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac ventricle development (GO:1904414) 1 0 .00 - < 0.01 1.00E00 1.00E00 core 3 O-glycan biosynthetic process (GO:0016269) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucan biosynthetic process (GO:0010962) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac ventricle development (GO:1904412) 1 0 .00 - < 0.01 1.00E00 1.00E00 core 2 O-glycan biosynthetic process (GO:0016268) 1 0 .00 - < 0.01 1.00E00 1.00E00 intracellular magnesium ion homeostasis (GO:0010961) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secretory granule organization (GO:1904411) 1 0 .00 - < 0.01 1.00E00 1.00E00 O-glycan processing (GO:0016266) 40 0 .01 - < 0.01 1.00E00 1.00E00 magnesium ion homeostasis (GO:0010960) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tyrosine phosphorylation of STAT protein (GO:0042509) 29 0 .01 - < 0.01 1.00E00 1.00E00 gap junction assembly (GO:0016264) 8 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound salvage (GO:0008655) 7 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid biosynthetic process (GO:0008654) 230 0 .07 - < 0.01 1.00E00 1.00E00 lipopolysaccharide metabolic process (GO:0008653) 1 0 .00 - < 0.01 1.00E00 1.00E00 selenocysteine catabolic process (GO:0016261) 1 0 .00 - < 0.01 1.00E00 1.00E00 amino acid biosynthetic process (GO:0008652) 69 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of retinoic acid biosynthetic process (GO:1900054) 1 0 .00 - < 0.01 1.00E00 1.00E00 selenocysteine biosynthetic process (GO:0016260) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of retinoic acid biosynthetic process (GO:1900053) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retinoic acid biosynthetic process (GO:1900052) 3 0 .00 - < 0.01 1.00E00 1.00E00 male genitalia development (GO:0030539) 24 0 .01 - < 0.01 1.00E00 1.00E00 embryonic genitalia morphogenesis (GO:0030538) 1 0 .00 - < 0.01 1.00E00 1.00E00 adult behavior (GO:0030534) 152 0 .04 - < 0.01 1.00E00 1.00E00 regulation of metal ion transport (GO:0010959) 378 0 .11 - < 0.01 1.00E00 1.00E00 regulation of secretory granule organization (GO:1904409) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amino acid import across plasma membrane (GO:0010958) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nitric oxide metabolic process (GO:1904407) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vitamin D biosynthetic process (GO:0010957) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nitric oxide metabolic process (GO:1904406) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcidiol 1-monooxygenase activity (GO:0010956) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein processing (GO:0010955) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein processing (GO:0010954) 25 0 .01 - < 0.01 1.00E00 1.00E00 response to formaldehyde (GO:1904404) 1 0 .00 - < 0.01 1.00E00 1.00E00 selenocysteine metabolic process (GO:0016259) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptidase activity (GO:0010952) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endopeptidase activity (GO:0010951) 20 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to Thyroid stimulating hormone (GO:1904401) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endopeptidase activity (GO:0010950) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to Thyroid stimulating hormone (GO:1904400) 2 0 .00 - < 0.01 1.00E00 1.00E00 N-glycan processing to lysosome (GO:0016256) 2 0 .00 - < 0.01 1.00E00 1.00E00 attachment of GPI anchor to protein (GO:0016255) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hemostasis (GO:1900048) 27 0 .01 - < 0.01 1.00E00 1.00E00 hexose transmembrane transport (GO:0008645) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of hemostasis (GO:1900047) 47 0 .01 - < 0.01 1.00E00 1.00E00 regulation of hemostasis (GO:1900046) 71 0 .02 - < 0.01 1.00E00 1.00E00 carbohydrate transport (GO:0008643) 63 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of protein K63-linked ubiquitination (GO:1900045) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein K63-linked ubiquitination (GO:1900044) 13 0 .00 - < 0.01 1.00E00 1.00E00 retina blood vessel maintenance (GO:0097601) 2 0 .00 - < 0.01 1.00E00 1.00E00 intracellular receptor signaling pathway (GO:0030522) 203 0 .06 - < 0.01 1.00E00 1.00E00 androgen receptor signaling pathway (GO:0030521) 24 0 .01 - < 0.01 1.00E00 1.00E00 estrogen receptor signaling pathway (GO:0030520) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of intestinal phytosterol absorption (GO:0010949) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle process (GO:0010948) 268 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by competitive promoter binding (GO:0010944) 13 0 .00 - < 0.01 1.00E00 1.00E00 protein deglutarylation (GO:0061698) 2 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic mitochondrial changes (GO:0008637) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to hypoxia (GO:1900039) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to hypoxia (GO:1900038) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to hypoxia (GO:1900037) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of autophagosome size (GO:0016243) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to heat (GO:1900036) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macroautophagy (GO:0016242) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macroautophagy (GO:0016241) 194 0 .06 - < 0.01 1.00E00 1.00E00 regulation of cellular response to heat (GO:1900034) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular detoxification of hydrogen peroxide (GO:0061692) 2 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to oxidative stress (GO:0008631) 22 0 .01 - < 0.01 1.00E00 1.00E00 autophagosome membrane docking (GO:0016240) 7 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of hydrogen peroxide (GO:0061691) 3 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to DNA damage (GO:0008630) 76 0 .02 - < 0.01 1.00E00 1.00E00 nuclear receptor-mediated steroid hormone signaling pathway (GO:0030518) 81 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of axon extension (GO:0030517) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of axon extension (GO:0030516) 82 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of BMP signaling pathway (GO:0030514) 60 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of BMP signaling pathway (GO:0030513) 38 0 .01 - < 0.01 1.00E00 1.00E00 respiratory electron transport chain (GO:0022904) 108 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of transforming growth factor beta receptor signaling pathway (GO:0030512) 98 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of transforming growth factor beta receptor signaling pathway (GO:0030511) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of BMP signaling pathway (GO:0030510) 108 0 .03 - < 0.01 1.00E00 1.00E00 electron transport chain (GO:0022900) 118 0 .03 - < 0.01 1.00E00 1.00E00 cytoplasmic microtubule depolymerization (GO:0010938) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage cytokine production (GO:0010936) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage cytokine production (GO:0010935) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of macroautophagy (GO:0016239) 96 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage tolerance induction (GO:0010933) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of macrophage tolerance induction (GO:0010932) 1 0 .00 - < 0.01 1.00E00 1.00E00 microautophagy (GO:0016237) 22 0 .01 - < 0.01 1.00E00 1.00E00 hormone-mediated apoptotic signaling pathway (GO:0008628) 5 0 .00 - < 0.01 1.00E00 1.00E00 detoxification of inorganic compound (GO:0061687) 24 0 .01 - < 0.01 1.00E00 1.00E00 macroautophagy (GO:0016236) 225 0 .07 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway in response to osmotic stress (GO:0008627) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ruffle assembly (GO:1900029) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ruffle assembly (GO:1900028) 7 0 .00 - < 0.01 1.00E00 1.00E00 granzyme-mediated apoptotic signaling pathway (GO:0008626) 1 0 .00 - < 0.01 1.00E00 1.00E00 extrinsic apoptotic signaling pathway via death domain receptors (GO:0008625) 45 0 .01 - < 0.01 1.00E00 1.00E00 regulation of ruffle assembly (GO:1900027) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of substrate adhesion-dependent cell spreading (GO:1900026) 43 0 .01 - < 0.01 1.00E00 1.00E00 telomere capping (GO:0016233) 16 0 .00 - < 0.01 1.00E00 1.00E00 chaperone-mediated autophagy (GO:0061684) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of substrate adhesion-dependent cell spreading (GO:1900025) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of substrate adhesion-dependent cell spreading (GO:1900024) 62 0 .02 - < 0.01 1.00E00 1.00E00 seminal vesicle morphogenesis (GO:0061682) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein kinase C activity (GO:1900020) 5 0 .00 - < 0.01 1.00E00 1.00E00 BMP signaling pathway (GO:0030509) 82 0 .02 - < 0.01 1.00E00 1.00E00 inorganic diphosphate transport (GO:0030505) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bone mineralization (GO:0030502) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of bone mineralization (GO:0030501) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of bone mineralization (GO:0030500) 80 0 .02 - < 0.01 1.00E00 1.00E00 cellular component assembly involved in morphogenesis (GO:0010927) 131 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of inositol-polyphosphate 5-phosphatase activity (GO:0010925) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatase activity (GO:0010923) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatase activity (GO:0010922) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatase activity (GO:0010921) 14 0 .00 - < 0.01 1.00E00 1.00E00 iron-sulfur cluster assembly (GO:0016226) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein kinase C activity (GO:1900019) 5 0 .00 - < 0.01 1.00E00 1.00E00 guanosine metabolic process (GO:0008617) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inositol phosphate biosynthetic process (GO:0010920) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytokine production involved in inflammatory response (GO:1900017) 26 0 .01 - < 0.01 1.00E00 1.00E00 pyridoxine biosynthetic process (GO:0008615) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytokine production involved in inflammatory response (GO:1900016) 37 0 .01 - < 0.01 1.00E00 1.00E00 pyridoxine metabolic process (GO:0008614) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cytokine production involved in inflammatory response (GO:1900015) 70 0 .02 - < 0.01 1.00E00 1.00E00 peptidyl-lysine modification to peptidyl-hypusine (GO:0008612) 2 0 .00 - < 0.01 1.00E00 1.00E00 ether lipid biosynthetic process (GO:0008611) 12 0 .00 - < 0.01 1.00E00 1.00E00 evoked neurotransmitter secretion (GO:0061670) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of corticotropin-releasing hormone receptor activity (GO:1900011) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inositol phosphate biosynthetic process (GO:0010919) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial membrane potential (GO:0010918) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial membrane potential (GO:0010917) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of very-low-density lipoprotein particle clearance (GO:0010916) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of very-low-density lipoprotein particle clearance (GO:0010915) 4 0 .00 - < 0.01 1.00E00 1.00E00 spontaneous neurotransmitter secretion (GO:0061669) 6 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial ribosome assembly (GO:0061668) 17 0 .00 - < 0.01 1.00E00 1.00E00 attachment of spindle microtubules to kinetochore (GO:0008608) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of eating behavior (GO:1903999) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of eating behavior (GO:1903998) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendrite development (GO:1900006) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of serine-type endopeptidase activity (GO:1900005) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of serine-type endopeptidase activity (GO:1900004) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of serine-type endopeptidase activity (GO:1900003) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010909) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heparan sulfate proteoglycan biosynthetic process (GO:0010908) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glucose metabolic process (GO:0010907) 47 0 .01 - < 0.01 1.00E00 1.00E00 regulation of glucose metabolic process (GO:0010906) 100 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of UDP-glucose catabolic process (GO:0010905) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of UDP-glucose catabolic process (GO:0010904) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of very-low-density lipoprotein particle remodeling (GO:0010903) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of very-low-density lipoprotein particle remodeling (GO:0010902) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of very-low-density lipoprotein particle remodeling (GO:0010901) 6 0 .00 - < 0.01 1.00E00 1.00E00 iron ion export across plasma membrane (GO:1903988) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylcholine catabolic process (GO:0010900) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intestinal D-glucose absorption (GO:1903985) 2 0 .00 - < 0.01 1.00E00 1.00E00 muscle attachment (GO:0016203) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of striated muscle tissue development (GO:0016202) 43 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of TRAIL-activated apoptotic signaling pathway (GO:1903984) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microglial cell activation (GO:1903980) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microglial cell activation (GO:1903979) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microglial cell activation (GO:1903978) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell migration (GO:1903977) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization (GO:0061646) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell migration (GO:1903976) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glial cell migration (GO:1903975) 19 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to CENP-A containing chromatin (GO:0061644) 4 0 .00 - < 0.01 1.00E00 1.00E00 chemorepulsion of axon (GO:0061643) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to macrophage colony-stimulating factor stimulus (GO:1903974) 2 0 .00 - < 0.01 1.00E00 1.00E00 chemoattraction of axon (GO:0061642) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to macrophage colony-stimulating factor stimulus (GO:1903972) 6 0 .00 - < 0.01 1.00E00 1.00E00 cytoskeleton-dependent cytokinesis (GO:0061640) 117 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of response to macrophage colony-stimulating factor (GO:1903971) 2 0 .00 - < 0.01 1.00E00 1.00E00 helper T cell enhancement of adaptive immune response (GO:0035397) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chemokine (C-X-C motif) ligand 9 production (GO:0035395) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to macrophage colony-stimulating factor (GO:1903969) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-X-C motif) ligand 9 production (GO:0035394) 1 0 .00 - < 0.01 1.00E00 1.00E00 monounsaturated fatty acid biosynthetic process (GO:1903966) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein complex stability (GO:0061635) 16 0 .00 - < 0.01 1.00E00 1.00E00 monounsaturated fatty acid catabolic process (GO:1903965) 1 0 .00 - < 0.01 1.00E00 1.00E00 monounsaturated fatty acid metabolic process (GO:1903964) 2 0 .00 - < 0.01 1.00E00 1.00E00 arachidonate transport (GO:1903963) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of anion transmembrane transport (GO:1903961) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of anion transmembrane transport (GO:1903960) 2 0 .00 - < 0.01 1.00E00 1.00E00 Roundabout signaling pathway (GO:0035385) 5 0 .00 - < 0.01 1.00E00 1.00E00 thioester biosynthetic process (GO:0035384) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of monoatomic anion transmembrane transport (GO:1903959) 5 0 .00 - < 0.01 1.00E00 1.00E00 thioester metabolic process (GO:0035383) 92 0 .03 - < 0.01 1.00E00 1.00E00 pharyngeal arch artery morphogenesis (GO:0061626) 10 0 .00 - < 0.01 1.00E00 1.00E00 sterol transmembrane transport (GO:0035382) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein targeting to mitochondrion (GO:1903955) 33 0 .01 - < 0.01 1.00E00 1.00E00 fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate (GO:0061624) 3 0 .00 - < 0.01 1.00E00 1.00E00 glycolytic process from galactose (GO:0061623) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycolytic process through glucose-1-phosphate (GO:0061622) 2 0 .00 - < 0.01 1.00E00 1.00E00 canonical glycolysis (GO:0061621) 19 0 .01 - < 0.01 1.00E00 1.00E00 glycolytic process through glucose-6-phosphate (GO:0061620) 21 0 .01 - < 0.01 1.00E00 1.00E00 carbon dioxide transmembrane transport (GO:0035378) 5 0 .00 - < 0.01 1.00E00 1.00E00 transepithelial water transport (GO:0035377) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of atrial cardiac muscle cell action potential (GO:1903949) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to microtubule (GO:0035372) 14 0 .00 - < 0.01 1.00E00 1.00E00 glycolytic process through fructose-6-phosphate (GO:0061615) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ventricular cardiac muscle cell action potential (GO:1903946) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hepatocyte apoptotic process (GO:1903945) 1 0 .00 - < 0.01 1.00E00 1.00E00 miRNA transcription (GO:0061614) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hepatocyte apoptotic process (GO:1903944) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hepatocyte apoptotic process (GO:1903943) 8 0 .00 - < 0.01 1.00E00 1.00E00 myo-inositol transport (GO:0015798) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of respiratory gaseous exchange (GO:1903942) 4 0 .00 - < 0.01 1.00E00 1.00E00 mannose to fructose-6-phosphate catabolic process (GO:0061611) 1 0 .00 - < 0.01 1.00E00 1.00E00 mannitol transmembrane transport (GO:0015797) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of respiratory gaseous exchange (GO:1903941) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of TORC2 signaling (GO:1903940) 3 0 .00 - < 0.01 1.00E00 1.00E00 glycerol transmembrane transport (GO:0015793) 8 0 .00 - < 0.01 1.00E00 1.00E00 polyol transmembrane transport (GO:0015791) 11 0 .00 - < 0.01 1.00E00 1.00E00 UDP-xylose transmembrane transport (GO:0015790) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of TORC2 signaling (GO:1903939) 12 0 .00 - < 0.01 1.00E00 1.00E00 thymine transport (GO:0035364) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to acrylamide (GO:1903937) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to sodium arsenite (GO:1903936) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035360) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to sodium arsenite (GO:1903935) 6 0 .00 - < 0.01 1.00E00 1.00E00 UDP-N-acetylgalactosamine transmembrane transport (GO:0015789) 2 0 .00 - < 0.01 1.00E00 1.00E00 UDP-glucuronate transmembrane transport (GO:0015787) 2 0 .00 - < 0.01 1.00E00 1.00E00 UDP-glucose transmembrane transport (GO:0015786) 3 0 .00 - < 0.01 1.00E00 1.00E00 GDP-fucose transmembrane transport (GO:0015783) 1 0 .00 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate transmembrane transport (GO:0015782) 1 0 .00 - < 0.01 1.00E00 1.00E00 nucleotide-sugar transmembrane transport (GO:0015780) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035359) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) 17 0 .00 - < 0.01 1.00E00 1.00E00 peroxisome proliferator activated receptor signaling pathway (GO:0035357) 10 0 .00 - < 0.01 1.00E00 1.00E00 intracellular triglyceride homeostasis (GO:0035356) 10 0 .00 - < 0.01 1.00E00 1.00E00 primary palate development (GO:1903929) 2 0 .00 - < 0.01 1.00E00 1.00E00 NAD transmembrane transport (GO:0035352) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to bisphenol A (GO:1903926) 4 0 .00 - < 0.01 1.00E00 1.00E00 heme transmembrane transport (GO:0035351) 3 0 .00 - < 0.01 1.00E00 1.00E00 FAD transmembrane transport (GO:0035350) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to bisphenol A (GO:1903925) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein processing in phagocytic vesicle (GO:1903923) 2 0 .00 - < 0.01 1.00E00 1.00E00 glucuronoside transport (GO:0015779) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein processing in phagocytic vesicle (GO:1903921) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of actin filament severing (GO:1903920) 1 0 .00 - < 0.01 1.00E00 1.00E00 polysaccharide transport (GO:0015774) 1 0 .00 - < 0.01 1.00E00 1.00E00 oligosaccharide transport (GO:0015772) 4 0 .00 - < 0.01 1.00E00 1.00E00 sucrose transport (GO:0015770) 4 0 .00 - < 0.01 1.00E00 1.00E00 viral budding via host ESCRT complex (GO:0039702) 22 0 .01 - < 0.01 1.00E00 1.00E00 coenzyme A transmembrane transport (GO:0035349) 3 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA transmembrane transport (GO:0035348) 1 0 .00 - < 0.01 1.00E00 1.00E00 hypoxanthine transport (GO:0035344) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of actin filament severing (GO:1903919) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of actin filament severing (GO:1903918) 2 0 .00 - < 0.01 1.00E00 1.00E00 angiotensin-activated signaling pathway involved in heart process (GO:0086098) 1 0 .00 - < 0.01 1.00E00 1.00E00 inosine transport (GO:0035340) 4 0 .00 - < 0.01 1.00E00 1.00E00 phospholipase C-activating angiotensin-activated signaling pathway (GO:0086097) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fusion of virus membrane with host plasma membrane (GO:1903914) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fusion of virus membrane with host plasma membrane (GO:1903913) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation (GO:1903912) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor clustering (GO:1903911) 10 0 .00 - < 0.01 1.00E00 1.00E00 disaccharide transport (GO:0015766) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of receptor clustering (GO:1903910) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of the force of heart contraction by cardiac conduction (GO:0086092) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of heart rate by cardiac conduction (GO:0086091) 42 0 .01 - < 0.01 1.00E00 1.00E00 mannose transmembrane transport (GO:0015761) 1 0 .00 - < 0.01 1.00E00 1.00E00 glucose-6-phosphate transport (GO:0015760) 6 0 .00 - < 0.01 1.00E00 1.00E00 L-valine biosynthetic process (GO:0009099) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-leucine biosynthetic process (GO:0009098) 2 0 .00 - < 0.01 1.00E00 1.00E00 isoleucine biosynthetic process (GO:0009097) 1 0 .00 - < 0.01 1.00E00 1.00E00 aromatic amino acid family biosynthetic process, prephenate pathway (GO:0009095) 3 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) 19 0 .01 - < 0.01 1.00E00 1.00E00 fatty-acyl-CoA metabolic process (GO:0035337) 41 0 .01 - < 0.01 1.00E00 1.00E00 cysteine catabolic process (GO:0009093) 4 0 .00 - < 0.01 1.00E00 1.00E00 homoserine metabolic process (GO:0009092) 4 0 .00 - < 0.01 1.00E00 1.00E00 long-chain fatty-acyl-CoA metabolic process (GO:0035336) 25 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-tyrosine dephosphorylation (GO:0035335) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of receptor clustering (GO:1903909) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hippo signaling (GO:0035332) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hippo signaling (GO:0035331) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane raft polarization (GO:1903906) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hippo signaling (GO:0035330) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of T cell polarity (GO:1903905) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of T cell polarity (GO:1903904) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of T cell polarity (GO:1903903) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of viral life cycle (GO:1903902) 25 0 .01 - < 0.01 1.00E00 1.00E00 galactose transmembrane transport (GO:0015757) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of viral life cycle (GO:1903901) 6 0 .00 - < 0.01 1.00E00 1.00E00 fucose transmembrane transport (GO:0015756) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of viral life cycle (GO:1903900) 115 0 .03 - < 0.01 1.00E00 1.00E00 fructose transmembrane transport (GO:0015755) 9 0 .00 - < 0.01 1.00E00 1.00E00 pentose transmembrane transport (GO:0015750) 2 0 .00 - < 0.01 1.00E00 1.00E00 methionine catabolic process (GO:0009087) 1 0 .00 - < 0.01 1.00E00 1.00E00 methionine biosynthetic process (GO:0009086) 12 0 .00 - < 0.01 1.00E00 1.00E00 hippo signaling (GO:0035329) 21 0 .01 - < 0.01 1.00E00 1.00E00 lysine biosynthetic process (GO:0009085) 2 0 .00 - < 0.01 1.00E00 1.00E00 glutamine family amino acid biosynthetic process (GO:0009084) 15 0 .00 - < 0.01 1.00E00 1.00E00 branched-chain amino acid catabolic process (GO:0009083) 22 0 .01 - < 0.01 1.00E00 1.00E00 branched-chain amino acid biosynthetic process (GO:0009082) 3 0 .00 - < 0.01 1.00E00 1.00E00 branched-chain amino acid metabolic process (GO:0009081) 26 0 .01 - < 0.01 1.00E00 1.00E00 pyruvate family amino acid catabolic process (GO:0009080) 10 0 .00 - < 0.01 1.00E00 1.00E00 monosaccharide transmembrane transport (GO:0015749) 46 0 .01 - < 0.01 1.00E00 1.00E00 organophosphate ester transport (GO:0015748) 172 0 .05 - < 0.01 1.00E00 1.00E00 urate transport (GO:0015747) 11 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His cell-Purkinje myocyte adhesion involved in cell communication (GO:0086073) 6 0 .00 - < 0.01 1.00E00 1.00E00 citrate transport (GO:0015746) 5 0 .00 - < 0.01 1.00E00 1.00E00 AV node cell-bundle of His cell adhesion involved in cell communication (GO:0086072) 1 0 .00 - < 0.01 1.00E00 1.00E00 SA node cell to atrial cardiac muscle cell communication (GO:0086070) 9 0 .00 - < 0.01 1.00E00 1.00E00 succinate transport (GO:0015744) 5 0 .00 - < 0.01 1.00E00 1.00E00 malate transport (GO:0015743) 3 0 .00 - < 0.01 1.00E00 1.00E00 alpha-ketoglutarate transport (GO:0015742) 7 0 .00 - < 0.01 1.00E00 1.00E00 fumarate transport (GO:0015741) 2 0 .00 - < 0.01 1.00E00 1.00E00 C4-dicarboxylate transport (GO:0015740) 26 0 .01 - < 0.01 1.00E00 1.00E00 pyruvate family amino acid biosynthetic process (GO:0009079) 3 0 .00 - < 0.01 1.00E00 1.00E00 pyruvate family amino acid metabolic process (GO:0009078) 13 0 .00 - < 0.01 1.00E00 1.00E00 non-replicative DNA transposition (GO:0098038) 1 0 .00 - < 0.01 1.00E00 1.00E00 aromatic amino acid family catabolic process (GO:0009074) 24 0 .01 - < 0.01 1.00E00 1.00E00 aromatic amino acid family biosynthetic process (GO:0009073) 4 0 .00 - < 0.01 1.00E00 1.00E00 aromatic amino acid metabolic process (GO:0009072) 40 0 .01 - < 0.01 1.00E00 1.00E00 hair cell differentiation (GO:0035315) 55 0 .02 - < 0.01 1.00E00 1.00E00 serine family amino acid catabolic process (GO:0009071) 12 0 .00 - < 0.01 1.00E00 1.00E00 serine family amino acid biosynthetic process (GO:0009070) 16 0 .00 - < 0.01 1.00E00 1.00E00 wound healing, spreading of epidermal cells (GO:0035313) 16 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His cell to Purkinje myocyte communication (GO:0086069) 14 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte to ventricular cardiac muscle cell communication (GO:0086068) 6 0 .00 - < 0.01 1.00E00 1.00E00 AV node cell to bundle of His cell communication (GO:0086067) 10 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell to AV node cell communication (GO:0086066) 15 0 .00 - < 0.01 1.00E00 1.00E00 cell communication involved in cardiac conduction (GO:0086065) 41 0 .01 - < 0.01 1.00E00 1.00E00 sialic acid transport (GO:0015739) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell communication by electrical coupling involved in cardiac conduction (GO:0086064) 14 0 .00 - < 0.01 1.00E00 1.00E00 glucuronate transmembrane transport (GO:0015738) 1 0 .00 - < 0.01 1.00E00 1.00E00 hexuronate transmembrane transport (GO:0015736) 1 0 .00 - < 0.01 1.00E00 1.00E00 uronic acid transmembrane transport (GO:0015735) 1 0 .00 - < 0.01 1.00E00 1.00E00 taurine transmembrane transport (GO:0015734) 8 0 .00 - < 0.01 1.00E00 1.00E00 prostaglandin transport (GO:0015732) 16 0 .00 - < 0.01 1.00E00 1.00E00 propanoate transmembrane transport (GO:0015730) 1 0 .00 - < 0.01 1.00E00 1.00E00 serine family amino acid metabolic process (GO:0009069) 31 0 .01 - < 0.01 1.00E00 1.00E00 aspartate family amino acid catabolic process (GO:0009068) 11 0 .00 - < 0.01 1.00E00 1.00E00 aspartate family amino acid biosynthetic process (GO:0009067) 21 0 .01 - < 0.01 1.00E00 1.00E00 aspartate family amino acid metabolic process (GO:0009066) 41 0 .01 - < 0.01 1.00E00 1.00E00 glutamine family amino acid catabolic process (GO:0009065) 24 0 .01 - < 0.01 1.00E00 1.00E00 glutamine family amino acid metabolic process (GO:0009064) 65 0 .02 - < 0.01 1.00E00 1.00E00 amino acid catabolic process (GO:0009063) 108 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of dephosphorylation (GO:0035306) 10 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid catabolic process (GO:0009062) 90 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of dephosphorylation (GO:0035305) 7 0 .00 - < 0.01 1.00E00 1.00E00 aerobic respiration (GO:0009060) 160 0 .05 - < 0.01 1.00E00 1.00E00 regulation of dephosphorylation (GO:0035303) 29 0 .01 - < 0.01 1.00E00 1.00E00 oxaloacetate transport (GO:0015729) 3 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling (GO:0086055) 1 0 .00 - < 0.01 1.00E00 1.00E00 mevalonate transport (GO:0015728) 1 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His cell to Purkinje myocyte communication by electrical coupling (GO:0086054) 2 0 .00 - < 0.01 1.00E00 1.00E00 AV node cell to bundle of His cell communication by electrical coupling (GO:0086053) 2 0 .00 - < 0.01 1.00E00 1.00E00 lactate transport (GO:0015727) 8 0 .00 - < 0.01 1.00E00 1.00E00 membrane repolarization during SA node cell action potential (GO:0086052) 1 0 .00 - < 0.01 1.00E00 1.00E00 formate transport (GO:0015724) 1 0 .00 - < 0.01 1.00E00 1.00E00 membrane repolarization during bundle of His cell action potential (GO:0086050) 1 0 .00 - < 0.01 1.00E00 1.00E00 bilirubin transport (GO:0015723) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylserine metabolic process (GO:0150178) 1 0 .00 - < 0.01 1.00E00 1.00E00 canalicular bile acid transport (GO:0015722) 2 0 .00 - < 0.01 1.00E00 1.00E00 bile acid and bile salt transport (GO:0015721) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylethanolamine metabolic process (GO:0150175) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylcholine metabolic process (GO:0150174) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylcholine metabolic process (GO:0150173) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylcholine metabolic process (GO:0150172) 10 0 .00 - < 0.01 1.00E00 1.00E00 macromolecule biosynthetic process (GO:0009059) 2905 1 .85 + 1.18 5.99E-01 1.00E00 macromolecule catabolic process (GO:0009057) 1033 0 .30 - < 0.01 1.00E00 1.00E00 response to cycloheximide (GO:0046898) 6 0 .00 - < 0.01 1.00E00 1.00E00 catabolic process (GO:0009056) 2013 3 .59 + 5.11 1.49E-02 1.00E00 pentose-phosphate shunt, non-oxidative branch (GO:0009052) 6 0 .00 - < 0.01 1.00E00 1.00E00 pentose-phosphate shunt, oxidative branch (GO:0009051) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipid biosynthetic process (GO:0046890) 185 0 .05 - < 0.01 1.00E00 1.00E00 membrane depolarization during bundle of His cell action potential (GO:0086048) 3 0 .00 - < 0.01 1.00E00 1.00E00 membrane depolarization during Purkinje myocyte cell action potential (GO:0086047) 3 0 .00 - < 0.01 1.00E00 1.00E00 membrane depolarization during SA node cell action potential (GO:0086046) 5 0 .00 - < 0.01 1.00E00 1.00E00 membrane depolarization during AV node cell action potential (GO:0086045) 5 0 .00 - < 0.01 1.00E00 1.00E00 monocarboxylic acid transport (GO:0015718) 155 0 .05 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell to AV node cell communication by electrical coupling (GO:0086044) 1 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His cell action potential (GO:0086043) 5 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell-cardiac muscle cell adhesion (GO:0086042) 7 0 .00 - < 0.01 1.00E00 1.00E00 hexose phosphate transport (GO:0015712) 6 0 .00 - < 0.01 1.00E00 1.00E00 organic anion transport (GO:0015711) 414 0 .12 - < 0.01 1.00E00 1.00E00 dosage compensation by inactivation of X chromosome (GO:0009048) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lipid biosynthetic process (GO:0046889) 95 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of hormone secretion (GO:0046888) 70 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of hormone secretion (GO:0046887) 147 1 .04 + 23.33 4.21E-02 1.00E00 positive regulation of hormone biosynthetic process (GO:0046886) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hormone biosynthetic process (GO:0046885) 25 0 .01 - < 0.01 1.00E00 1.00E00 follicle-stimulating hormone secretion (GO:0046884) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hormone secretion (GO:0046883) 264 1 .08 + 12.99 7.46E-02 1.00E00 negative regulation of follicle-stimulating hormone secretion (GO:0046882) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of follicle-stimulating hormone secretion (GO:0046881) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of follicle-stimulating hormone secretion (GO:0046880) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell membrane potential (GO:0086036) 7 0 .00 - < 0.01 1.00E00 1.00E00 thiosulfate transport (GO:0015709) 1 0 .00 - < 0.01 1.00E00 1.00E00 nitrite transport (GO:0015707) 1 0 .00 - < 0.01 1.00E00 1.00E00 nitrate transmembrane transport (GO:0015706) 3 0 .00 - < 0.01 1.00E00 1.00E00 iodide transport (GO:0015705) 9 0 .00 - < 0.01 1.00E00 1.00E00 bicarbonate transport (GO:0015701) 37 0 .01 - < 0.01 1.00E00 1.00E00 arsenite transport (GO:0015700) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-17A production (GO:0150153) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-17A production (GO:0150151) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of programmed necrotic cell death (GO:0062099) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of programmed necrotic cell death (GO:0062098) 32 0 .01 - < 0.01 1.00E00 1.00E00 hormone secretion (GO:0046879) 94 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of saliva secretion (GO:0046878) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of saliva secretion (GO:0046877) 8 0 .00 - < 0.01 1.00E00 1.00E00 stomach development (GO:0062094) 5 0 .00 - < 0.01 1.00E00 1.00E00 quinolinate metabolic process (GO:0046874) 5 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte to ventricular cardiac muscle cell signaling (GO:0086029) 5 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His cell to Purkinje myocyte signaling (GO:0086028) 5 0 .00 - < 0.01 1.00E00 1.00E00 AV node cell to bundle of His cell signaling (GO:0086027) 7 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell to AV node cell signaling (GO:0086026) 14 0 .00 - < 0.01 1.00E00 1.00E00 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process (GO:0086023) 1 0 .00 - < 0.01 1.00E00 1.00E00 SA node cell to atrial cardiac muscle cell communication by electrical coupling (GO:0086021) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell junction disassembly (GO:0150147) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell junction disassembly (GO:0150146) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD80 production (GO:0150145) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD80 production (GO:0150143) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of CD86 production (GO:0150142) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of CD86 production (GO:0150140) 1 0 .00 - < 0.01 1.00E00 1.00E00 terpenoid transport (GO:0046865) 4 0 .00 - < 0.01 1.00E00 1.00E00 isoprenoid transport (GO:0046864) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in cardiac conduction (GO:0086019) 24 0 .01 - < 0.01 1.00E00 1.00E00 SA node cell to atrial cardiac muscle cell signaling (GO:0086018) 7 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte action potential (GO:0086017) 3 0 .00 - < 0.01 1.00E00 1.00E00 AV node cell action potential (GO:0086016) 7 0 .00 - < 0.01 1.00E00 1.00E00 SA node cell action potential (GO:0086015) 7 0 .00 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle cell action potential (GO:0086014) 14 0 .00 - < 0.01 1.00E00 1.00E00 membrane repolarization during cardiac muscle cell action potential (GO:0086013) 21 0 .01 - < 0.01 1.00E00 1.00E00 membrane depolarization during cardiac muscle cell action potential (GO:0086012) 17 0 .00 - < 0.01 1.00E00 1.00E00 membrane repolarization during action potential (GO:0086011) 23 0 .01 - < 0.01 1.00E00 1.00E00 membrane depolarization during action potential (GO:0086010) 23 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylinositol dephosphorylation (GO:0046856) 29 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylinositol phosphate biosynthetic process (GO:0046854) 56 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of bone remodeling (GO:0046851) 18 0 .01 - < 0.01 1.00E00 1.00E00 membrane repolarization (GO:0086009) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of bone remodeling (GO:0046850) 53 0 .02 - < 0.01 1.00E00 1.00E00 detection of diacyl bacterial lipopeptide (GO:0042496) 2 0 .00 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle cell action potential (GO:0086005) 22 0 .01 - < 0.01 1.00E00 1.00E00 detection of triacyl bacterial lipopeptide (GO:0042495) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell contraction (GO:0086004) 35 0 .01 - < 0.01 1.00E00 1.00E00 detection of bacterial lipoprotein (GO:0042494) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell contraction (GO:0086003) 52 0 .02 - < 0.01 1.00E00 1.00E00 cardiac muscle cell action potential involved in contraction (GO:0086002) 46 0 .01 - < 0.01 1.00E00 1.00E00 gamma-delta T cell differentiation (GO:0042492) 9 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell action potential (GO:0086001) 57 0 .02 - < 0.01 1.00E00 1.00E00 inner ear auditory receptor cell differentiation (GO:0042491) 47 0 .01 - < 0.01 1.00E00 1.00E00 mechanoreceptor differentiation (GO:0042490) 72 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of interleukin-33 production (GO:0150129) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-33 production (GO:0150127) 1 0 .00 - < 0.01 1.00E00 1.00E00 bone remodeling (GO:0046849) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of neuromuscular junction development (GO:1904398) 3 0 .00 - < 0.01 1.00E00 1.00E00 filopodium assembly (GO:0046847) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of neuromuscular junction development (GO:1904396) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904395) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904394) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle acetylcholine-gated channel clustering (GO:1904393) 7 0 .00 - < 0.01 1.00E00 1.00E00 cone retinal bipolar cell differentiation (GO:1904390) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of odontogenesis of dentin-containing tooth (GO:0042489) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of odontogenesis of dentin-containing tooth (GO:0042488) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of odontogenesis of dentin-containing tooth (GO:0042487) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of odontogenesis (GO:0042483) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of odontogenesis (GO:0042482) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of odontogenesis (GO:0042481) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cell-substrate junction organization (GO:0150118) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell-substrate junction organization (GO:0150117) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell-substrate junction organization (GO:0150116) 68 0 .02 - < 0.01 1.00E00 1.00E00 cell-substrate junction organization (GO:0150115) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of transepithelial transport (GO:0150111) 4 0 .00 - < 0.01 1.00E00 1.00E00 rod bipolar cell differentiation (GO:1904389) 2 0 .00 - < 0.01 1.00E00 1.00E00 phospholipid dephosphorylation (GO:0046839) 42 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to L-phenylalanine derivative (GO:1904387) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to L-phenylalanine derivative (GO:1904386) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to angiotensin (GO:1904385) 31 0 .01 - < 0.01 1.00E00 1.00E00 glycolipid transport (GO:0046836) 7 0 .00 - < 0.01 1.00E00 1.00E00 carbohydrate phosphorylation (GO:0046835) 24 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to sodium phosphate (GO:1904384) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to sodium phosphate (GO:1904383) 10 0 .00 - < 0.01 1.00E00 1.00E00 lipid phosphorylation (GO:0046834) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of RNA export from nucleus (GO:0046833) 5 0 .00 - < 0.01 1.00E00 1.00E00 mannose trimming involved in glycoprotein ERAD pathway (GO:1904382) 3 0 .00 - < 0.01 1.00E00 1.00E00 Golgi apparatus mannose trimming (GO:1904381) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RNA export from nucleus (GO:0046832) 3 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum mannose trimming (GO:1904380) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of RNA export from nucleus (GO:0046831) 15 0 .00 - < 0.01 1.00E00 1.00E00 odontogenesis (GO:0042476) 124 0 .04 - < 0.01 1.00E00 1.00E00 odontogenesis of dentin-containing tooth (GO:0042475) 84 0 .02 - < 0.01 1.00E00 1.00E00 middle ear morphogenesis (GO:0042474) 21 0 .01 - < 0.01 1.00E00 1.00E00 lamellipodium organization (GO:0097581) 45 0 .01 - < 0.01 1.00E00 1.00E00 outer ear morphogenesis (GO:0042473) 9 0 .00 - < 0.01 1.00E00 1.00E00 inner ear morphogenesis (GO:0042472) 109 0 .03 - < 0.01 1.00E00 1.00E00 ear morphogenesis (GO:0042471) 130 0 .04 - < 0.01 1.00E00 1.00E00 regulation of transmembrane transporter activity (GO:0022898) 144 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cell-cell junction (GO:0150107) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell-cell junction (GO:0150106) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell-cell junction (GO:0150105) 20 0 .01 - < 0.01 1.00E00 1.00E00 transport across blood-brain barrier (GO:0150104) 87 0 .03 - < 0.01 1.00E00 1.00E00 reactive gliosis (GO:0150103) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monocyte activation (GO:0150102) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule anchoring at centrosome (GO:0150101) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cell periphery (GO:1904377) 76 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein export from nucleus (GO:0046827) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cell periphery (GO:1904376) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cell periphery (GO:1904375) 154 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of protein export from nucleus (GO:0046826) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac epithelial to mesenchymal transition (GO:0062044) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein export from nucleus (GO:0046825) 37 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac epithelial to mesenchymal transition (GO:0062043) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleocytoplasmic transport (GO:0046824) 64 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cardiac epithelial to mesenchymal transition (GO:0062042) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to kainic acid (GO:1904373) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleocytoplasmic transport (GO:0046823) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to actin cortical patch (GO:1904372) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleocytoplasmic transport (GO:0046822) 120 0 .03 - < 0.01 1.00E00 1.00E00 regulation of protein localization to actin cortical patch (GO:1904370) 1 0 .00 - < 0.01 1.00E00 1.00E00 vacuole fusion (GO:0097576) 12 0 .00 - < 0.01 1.00E00 1.00E00 eye photoreceptor cell development (GO:0042462) 37 0 .01 - < 0.01 1.00E00 1.00E00 photoreceptor cell development (GO:0042461) 52 0 .02 - < 0.01 1.00E00 1.00E00 fatty acid elongation (GO:0030497) 14 0 .00 - < 0.01 1.00E00 1.00E00 maturation of SSU-rRNA (GO:0030490) 53 0 .02 - < 0.01 1.00E00 1.00E00 sensory perception of hot stimulus (GO:0062036) 1 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of cold stimulus (GO:0062035) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic sister chromatid segregation (GO:0062033) 9 0 .00 - < 0.01 1.00E00 1.00E00 coreceptor-mediated virion attachment to host cell (GO:0046814) 1 0 .00 - < 0.01 1.00E00 1.00E00 receptor-mediated virion attachment to host cell (GO:0046813) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stress granule assembly (GO:0062030) 2 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside biosynthetic process (GO:0042455) 11 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoside catabolic process (GO:0042454) 14 0 .00 - < 0.01 1.00E00 1.00E00 deoxyguanosine metabolic process (GO:0042453) 2 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside biosynthetic process (GO:0042451) 11 0 .00 - < 0.01 1.00E00 1.00E00 arginine biosynthetic process via ornithine (GO:0042450) 2 0 .00 - < 0.01 1.00E00 1.00E00 tRNA methylation (GO:0030488) 39 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of stress granule assembly (GO:0062029) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stress granule assembly (GO:0062028) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of telomere maintenance via telomere lengthening (GO:1904358) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of SCF-dependent proteasomal ubiquitin-dependent catabolic process (GO:0062026) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomere maintenance via telomere lengthening (GO:1904357) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0062025) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomere maintenance via telomere lengthening (GO:1904356) 54 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of telomere capping (GO:1904355) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of telomere capping (GO:1904354) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of telomere capping (GO:1904353) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein catabolic process in the vacuole (GO:1904352) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein catabolic process in the vacuole (GO:1904351) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process in the vacuole (GO:1904350) 14 0 .00 - < 0.01 1.00E00 1.00E00 progesterone metabolic process (GO:0042448) 14 0 .00 - < 0.01 1.00E00 1.00E00 anterior/posterior axis specification, embryo (GO:0008595) 20 0 .01 - < 0.01 1.00E00 1.00E00 photoreceptor cell morphogenesis (GO:0008594) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Notch signaling pathway (GO:0008593) 100 0 .03 - < 0.01 1.00E00 1.00E00 calcium ion transmembrane import into cytosol (GO:0097553) 95 0 .03 - < 0.01 1.00E00 1.00E00 regulation of Toll signaling pathway (GO:0008592) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway, calcium modulating pathway (GO:0008591) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial double-strand break repair via homologous recombination (GO:0097552) 1 0 .00 - < 0.01 1.00E00 1.00E00 phenylethylamine metabolic process (GO:0042443) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial double-strand break repair (GO:0097551) 1 0 .00 - < 0.01 1.00E00 1.00E00 eye pigment metabolic process (GO:0042441) 2 0 .00 - < 0.01 1.00E00 1.00E00 pigment metabolic process (GO:0042440) 65 0 .02 - < 0.01 1.00E00 1.00E00 nuclear migration along microtubule (GO:0030473) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylcholine catabolic process (GO:0010899) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of small intestine smooth muscle contraction (GO:1904349) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride catabolic process (GO:0010898) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of triglyceride catabolic process (GO:0010897) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of small intestine smooth muscle contraction (GO:1904347) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of triglyceride catabolic process (GO:0010896) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gastric mucosal blood circulation (GO:1904346) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of small molecule metabolic process (GO:0062014) 114 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of small molecule metabolic process (GO:0062013) 151 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of steroid biosynthetic process (GO:0010894) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of gastric mucosal blood circulation (GO:1904344) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of small molecule metabolic process (GO:0062012) 330 0 .10 - < 0.01 1.00E00 1.00E00 axon midline choice point recognition (GO:0016199) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of steroid biosynthetic process (GO:0010893) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of colon smooth muscle contraction (GO:1904343) 1 0 .00 - < 0.01 1.00E00 1.00E00 axon choice point recognition (GO:0016198) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smoothened signaling pathway (GO:0008589) 88 0 .03 - < 0.01 1.00E00 1.00E00 endosomal transport (GO:0016197) 265 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of triglyceride storage (GO:0010891) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of colon smooth muscle contraction (GO:1904341) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride storage (GO:0010890) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dopaminergic neuron differentiation (GO:1904340) 3 0 .00 - < 0.01 1.00E00 1.00E00 ethanolamine-containing compound metabolic process (GO:0042439) 8 0 .00 - < 0.01 1.00E00 1.00E00 melanin biosynthetic process (GO:0042438) 14 0 .00 - < 0.01 1.00E00 1.00E00 female gonad development (GO:0008585) 98 1 .03 + 35.00 2.82E-02 1.00E00 male gonad development (GO:0008584) 148 0 .04 - < 0.01 1.00E00 1.00E00 indole-containing compound catabolic process (GO:0042436) 9 0 .00 - < 0.01 1.00E00 1.00E00 vesicle-mediated transport (GO:0016192) 1304 0 .38 - < 0.01 1.00E00 1.00E00 indole-containing compound biosynthetic process (GO:0042435) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic assembly at neuromuscular junction (GO:0008582) 10 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle uncoating (GO:0016191) 3 0 .00 - < 0.01 1.00E00 1.00E00 indole metabolic process (GO:0042431) 1 0 .00 - < 0.01 1.00E00 1.00E00 indole-containing compound metabolic process (GO:0042430) 23 0 .01 - < 0.01 1.00E00 1.00E00 secondary palate development (GO:0062009) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of triglyceride storage (GO:0010889) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopaminergic neuron differentiation (GO:1904339) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipid storage (GO:0010888) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of dopaminergic neuron differentiation (GO:1904338) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol storage (GO:0010887) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cholesterol storage (GO:0010886) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholesterol storage (GO:0010885) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid storage (GO:0010884) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lipid storage (GO:0010883) 46 0 .01 - < 0.01 1.00E00 1.00E00 synaptic vesicle to endosome fusion (GO:0016189) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of error-prone translesion synthesis (GO:1904333) 1 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle maturation (GO:0016188) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO:0010881) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of error-prone translesion synthesis (GO:1904331) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac endothelial to mesenchymal transition (GO:0062000) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of myofibroblast contraction (GO:1904330) 1 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding from presynaptic endocytic zone membrane (GO:0016185) 10 0 .00 - < 0.01 1.00E00 1.00E00 serotonin metabolic process (GO:0042428) 10 0 .00 - < 0.01 1.00E00 1.00E00 thymus epithelium morphogenesis (GO:0097536) 2 0 .00 - < 0.01 1.00E00 1.00E00 serotonin biosynthetic process (GO:0042427) 3 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle coating (GO:0016183) 5 0 .00 - < 0.01 1.00E00 1.00E00 lymphoid lineage cell migration into thymus (GO:0097535) 2 0 .00 - < 0.01 1.00E00 1.00E00 choline catabolic process (GO:0042426) 4 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle budding from endosome (GO:0016182) 3 0 .00 - < 0.01 1.00E00 1.00E00 lymphoid lineage cell migration (GO:0097534) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular stress response to acid chemical (GO:0097533) 2 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine catabolic process (GO:0042424) 11 0 .00 - < 0.01 1.00E00 1.00E00 snRNA processing (GO:0016180) 36 0 .01 - < 0.01 1.00E00 1.00E00 stress response to acid chemical (GO:0097532) 2 0 .00 - < 0.01 1.00E00 1.00E00 mast cell migration (GO:0097531) 7 0 .00 - < 0.01 1.00E00 1.00E00 catecholamine biosynthetic process (GO:0042423) 19 0 .01 - < 0.01 1.00E00 1.00E00 granulocyte migration (GO:0097530) 91 0 .03 - < 0.01 1.00E00 1.00E00 norepinephrine biosynthetic process (GO:0042421) 8 0 .00 - < 0.01 1.00E00 1.00E00 dopamine catabolic process (GO:0042420) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of complement activation, alternative pathway (GO:0030451) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of complement activation, classical pathway (GO:0030450) 8 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol transport involved in cholesterol storage (GO:0010879) 1 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol storage (GO:0010878) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myofibroblast contraction (GO:1904328) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipid transport involved in lipid storage (GO:0010877) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cytosolic proteasome complex (GO:1904327) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipid localization (GO:0010876) 357 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of cholesterol efflux (GO:0010875) 26 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cholesterol efflux (GO:0010874) 37 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to forskolin (GO:1904322) 13 0 .00 - < 0.01 1.00E00 1.00E00 myeloid leukocyte migration (GO:0097529) 131 0 .04 - < 0.01 1.00E00 1.00E00 response to forskolin (GO:1904321) 13 0 .00 - < 0.01 1.00E00 1.00E00 execution phase of necroptosis (GO:0097528) 2 0 .00 - < 0.01 1.00E00 1.00E00 necroptotic signaling pathway (GO:0097527) 8 0 .00 - < 0.01 1.00E00 1.00E00 epinephrine biosynthetic process (GO:0042418) 2 0 .00 - < 0.01 1.00E00 1.00E00 dopamine metabolic process (GO:0042417) 31 0 .01 - < 0.01 1.00E00 1.00E00 dopamine biosynthetic process (GO:0042416) 9 0 .00 - < 0.01 1.00E00 1.00E00 norepinephrine metabolic process (GO:0042415) 16 0 .00 - < 0.01 1.00E00 1.00E00 epinephrine metabolic process (GO:0042414) 3 0 .00 - < 0.01 1.00E00 1.00E00 carnitine catabolic process (GO:0042413) 1 0 .00 - < 0.01 1.00E00 1.00E00 taurine biosynthetic process (GO:0042412) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of complement activation (GO:0030449) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of triglyceride biosynthetic process (GO:0010868) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride biosynthetic process (GO:0010867) 13 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine (GO:1904317) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of triglyceride biosynthetic process (GO:0010866) 19 0 .01 - < 0.01 1.00E00 1.00E00 response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine (GO:1904316) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to methamphetamine hydrochloride (GO:1904313) 4 0 .00 - < 0.01 1.00E00 1.00E00 cristae formation (GO:0042407) 16 0 .00 - < 0.01 1.00E00 1.00E00 thyroid hormone catabolic process (GO:0042404) 1 0 .00 - < 0.01 1.00E00 1.00E00 thyroid hormone metabolic process (GO:0042403) 22 0 .01 - < 0.01 1.00E00 1.00E00 biogenic amine catabolic process (GO:0042402) 20 0 .01 - < 0.01 1.00E00 1.00E00 base-excision repair, AP site formation via deaminated base removal (GO:0097510) 1 0 .00 - < 0.01 1.00E00 1.00E00 biogenic amine biosynthetic process (GO:0042401) 35 0 .01 - < 0.01 1.00E00 1.00E00 peristalsis (GO:0030432) 12 0 .00 - < 0.01 1.00E00 1.00E00 sleep (GO:0030431) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gastro-intestinal system smooth muscle contraction (GO:1904306) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gastro-intestinal system smooth muscle contraction (GO:1904304) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of maternal process involved in parturition (GO:1904303) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of maternal process involved in parturition (GO:1904301) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcytosis (GO:1904300) 2 0 .00 - < 0.01 1.00E00 1.00E00 epidermis development (GO:0008544) 341 0 .10 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway (GO:0008543) 103 0 .03 - < 0.01 1.00E00 1.00E00 sialylation (GO:0097503) 10 0 .00 - < 0.01 1.00E00 1.00E00 visual learning (GO:0008542) 51 0 .01 - < 0.01 1.00E00 1.00E00 mannosylation (GO:0097502) 22 0 .01 - < 0.01 1.00E00 1.00E00 stress response to metal ion (GO:0097501) 22 0 .01 - < 0.01 1.00E00 1.00E00 receptor localization to non-motile cilium (GO:0097500) 5 0 .00 - < 0.01 1.00E00 1.00E00 chromosome localization (GO:0050000) 105 0 .03 - < 0.01 1.00E00 1.00E00 siRNA processing (GO:0030422) 8 0 .00 - < 0.01 1.00E00 1.00E00 defecation (GO:0030421) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proton-transporting ATPase activity, rotational mechanism (GO:0010849) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of reciprocal meiotic recombination (GO:0010845) 3 0 .00 - < 0.01 1.00E00 1.00E00 retina layer formation (GO:0010842) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of circadian sleep/wake cycle, wakefulness (GO:0010841) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, wakefulness (GO:0010840) 4 0 .00 - < 0.01 1.00E00 1.00E00 respiratory chain complex IV assembly (GO:0008535) 31 0 .01 - < 0.01 1.00E00 1.00E00 calcium activated galactosylceramide scrambling (GO:0061591) 3 0 .00 - < 0.01 1.00E00 1.00E00 calcium activated phosphatidylcholine scrambling (GO:0061590) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of keratinocyte proliferation (GO:0010839) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of keratinocyte proliferation (GO:0010838) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of keratinocyte proliferation (GO:0010837) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein ADP-ribosylation (GO:0010836) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein ADP-ribosylation (GO:0010835) 8 0 .00 - < 0.01 1.00E00 1.00E00 telomere maintenance via telomere lengthening (GO:0010833) 29 0 .01 - < 0.01 1.00E00 1.00E00 glycoside catabolic process (GO:0016139) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myotube differentiation (GO:0010832) 15 0 .00 - < 0.01 1.00E00 1.00E00 calcium activated phosphatidylserine scrambling (GO:0061589) 4 0 .00 - < 0.01 1.00E00 1.00E00 calcium activated phospholipid scrambling (GO:0061588) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myotube differentiation (GO:0010831) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycoside metabolic process (GO:0016137) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of myotube differentiation (GO:0010830) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by transcription factor localization (GO:0061586) 1 0 .00 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell migration (GO:0061582) 2 0 .00 - < 0.01 1.00E00 1.00E00 colon epithelial cell migration (GO:0061580) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA-templated viral transcription (GO:0039695) 1 0 .00 - < 0.01 1.00E00 1.00E00 viral RNA genome replication (GO:0039694) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of D-glucose transmembrane transport (GO:0010829) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of D-glucose transmembrane transport (GO:0010828) 44 0 .01 - < 0.01 1.00E00 1.00E00 single stranded viral RNA replication via double stranded DNA intermediate (GO:0039692) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of D-glucose transmembrane transport (GO:0010827) 75 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of centrosome duplication (GO:0010826) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of centrosome duplication (GO:0010825) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of centrosome duplication (GO:0010824) 49 0 .01 - < 0.01 1.00E00 1.00E00 sterol catabolic process (GO:0016127) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrion organization (GO:0010821) 117 0 .03 - < 0.01 1.00E00 1.00E00 sterol biosynthetic process (GO:0016126) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell chemotaxis (GO:0010820) 14 0 .00 - < 0.01 1.00E00 1.00E00 calcium ion transmembrane transport via high voltage-gated calcium channel (GO:0061577) 3 0 .00 - < 0.01 1.00E00 1.00E00 sterol metabolic process (GO:0016125) 131 1 .04 + 26.18 3.76E-02 1.00E00 xanthophyll catabolic process (GO:0016124) 1 0 .00 - < 0.01 1.00E00 1.00E00 xanthophyll biosynthetic process (GO:0016123) 1 0 .00 - < 0.01 1.00E00 1.00E00 xanthophyll metabolic process (GO:0016122) 2 0 .00 - < 0.01 1.00E00 1.00E00 actin filament bundle retrograde transport (GO:0061573) 1 0 .00 - < 0.01 1.00E00 1.00E00 actin filament bundle organization (GO:0061572) 66 0 .02 - < 0.01 1.00E00 1.00E00 carotene catabolic process (GO:0016121) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative stranded viral RNA replication (GO:0039689) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell chemotaxis (GO:0010819) 15 0 .00 - < 0.01 1.00E00 1.00E00 T cell chemotaxis (GO:0010818) 15 0 .00 - < 0.01 1.00E00 1.00E00 calcitonin catabolic process (GO:0010816) 1 0 .00 - < 0.01 1.00E00 1.00E00 bradykinin catabolic process (GO:0010815) 7 0 .00 - < 0.01 1.00E00 1.00E00 substance P catabolic process (GO:0010814) 3 0 .00 - < 0.01 1.00E00 1.00E00 carotene metabolic process (GO:0016119) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuropeptide catabolic process (GO:0010813) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell-substrate adhesion (GO:0010812) 60 0 .02 - < 0.01 1.00E00 1.00E00 carotenoid catabolic process (GO:0016118) 1 0 .00 - < 0.01 1.00E00 1.00E00 carotenoid biosynthetic process (GO:0016117) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell-substrate adhesion (GO:0010811) 128 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of PERK-mediated unfolded protein response (GO:1903899) 4 0 .00 - < 0.01 1.00E00 1.00E00 carotenoid metabolic process (GO:0016116) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell-substrate adhesion (GO:0010810) 220 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of PERK-mediated unfolded protein response (GO:1903898) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of PERK-mediated unfolded protein response (GO:1903897) 16 0 .00 - < 0.01 1.00E00 1.00E00 terpenoid catabolic process (GO:0016115) 8 0 .00 - < 0.01 1.00E00 1.00E00 terpenoid biosynthetic process (GO:0016114) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of IRE1-mediated unfolded protein response (GO:1903896) 8 0 .00 - < 0.01 1.00E00 1.00E00 axon development (GO:0061564) 427 0 .12 - < 0.01 1.00E00 1.00E00 negative regulation of IRE1-mediated unfolded protein response (GO:1903895) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of IRE1-mediated unfolded protein response (GO:1903894) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ATF6-mediated unfolded protein response (GO:1903893) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ATF6-mediated unfolded protein response (GO:1903892) 2 0 .00 - < 0.01 1.00E00 1.00E00 tetraterpenoid catabolic process (GO:0016110) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ATF6-mediated unfolded protein response (GO:1903891) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle priming (GO:0010808) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle priming (GO:0010807) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) 29 0 .01 - < 0.01 1.00E00 1.00E00 tetraterpenoid biosynthetic process (GO:0016109) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tumor necrosis factor-mediated signaling pathway (GO:0010803) 64 0 .02 - < 0.01 1.00E00 1.00E00 tetraterpenoid metabolic process (GO:0016108) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidyl-threonine phosphorylation (GO:0010801) 7 0 .00 - < 0.01 1.00E00 1.00E00 sesquiterpenoid catabolic process (GO:0016107) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptidyl-threonine phosphorylation (GO:0010800) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chemokine (C-C motif) ligand 20 production (GO:1903886) 1 0 .00 - < 0.01 1.00E00 1.00E00 triterpenoid biosynthetic process (GO:0016104) 1 0 .00 - < 0.01 1.00E00 1.00E00 diterpenoid catabolic process (GO:0016103) 4 0 .00 - < 0.01 1.00E00 1.00E00 diterpenoid biosynthetic process (GO:0016102) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chemokine (C-C motif) ligand 20 production (GO:1903884) 1 0 .00 - < 0.01 1.00E00 1.00E00 ganglion morphogenesis (GO:0061552) 2 0 .00 - < 0.01 1.00E00 1.00E00 diterpenoid metabolic process (GO:0016101) 91 1 .03 + 37.69 2.62E-02 1.00E00 positive regulation of interleukin-17-mediated signaling pathway (GO:1903883) 1 0 .00 - < 0.01 1.00E00 1.00E00 trigeminal ganglion development (GO:0061551) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of interleukin-17-mediated signaling pathway (GO:1903882) 1 0 .00 - < 0.01 1.00E00 1.00E00 cranial ganglion development (GO:0061550) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of interleukin-17-mediated signaling pathway (GO:1903881) 2 0 .00 - < 0.01 1.00E00 1.00E00 membrane fusion involved in viral entry into host cell (GO:0039663) 4 0 .00 - < 0.01 1.00E00 1.00E00 sympathetic ganglion development (GO:0061549) 9 0 .00 - < 0.01 1.00E00 1.00E00 ganglion development (GO:0061548) 17 0 .00 - < 0.01 1.00E00 1.00E00 fusion of virus membrane with host endosome membrane (GO:0039654) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tube diameter (GO:0035296) 158 0 .05 - < 0.01 1.00E00 1.00E00 tube development (GO:0035295) 919 0 .27 - < 0.01 1.00E00 1.00E00 extraembryonic membrane development (GO:1903867) 13 0 .00 - < 0.01 1.00E00 1.00E00 glutamate secretion, neurotransmission (GO:0061535) 3 0 .00 - < 0.01 1.00E00 1.00E00 trunk segmentation (GO:0035290) 5 0 .00 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid secretion, neurotransmission (GO:0061534) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative phosphorylation (GO:1903862) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendrite extension (GO:1903861) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of dendrite extension (GO:1903860) 5 0 .00 - < 0.01 1.00E00 1.00E00 brain segmentation (GO:0035284) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendrite extension (GO:1903859) 28 0 .01 - < 0.01 1.00E00 1.00E00 central nervous system segmentation (GO:0035283) 4 0 .00 - < 0.01 1.00E00 1.00E00 segmentation (GO:0035282) 97 0 .03 - < 0.01 1.00E00 1.00E00 acetylcholine secretion (GO:0061526) 1 0 .00 - < 0.01 1.00E00 1.00E00 hindgut development (GO:0061525) 8 0 .00 - < 0.01 1.00E00 1.00E00 pre-miRNA export from nucleus (GO:0035281) 2 0 .00 - < 0.01 1.00E00 1.00E00 cilium disassembly (GO:0061523) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cristae formation (GO:1903852) 4 0 .00 - < 0.01 1.00E00 1.00E00 Langerhans cell differentiation (GO:0061520) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cristae formation (GO:1903850) 5 0 .00 - < 0.01 1.00E00 1.00E00 miRNA-mediated gene silencing by mRNA destabilization (GO:0035279) 5 0 .00 - < 0.01 1.00E00 1.00E00 miRNA-mediated gene silencing by inhibition of translation (GO:0035278) 18 0 .01 - < 0.01 1.00E00 1.00E00 macrophage homeostasis (GO:0061519) 3 0 .00 - < 0.01 1.00E00 1.00E00 microglial cell proliferation (GO:0061518) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aorta morphogenesis (GO:1903849) 2 0 .00 - < 0.01 1.00E00 1.00E00 macrophage proliferation (GO:0061517) 9 0 .00 - < 0.01 1.00E00 1.00E00 exocrine system development (GO:0035272) 46 0 .01 - < 0.01 1.00E00 1.00E00 monocyte proliferation (GO:0061516) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aorta morphogenesis (GO:1903847) 2 0 .00 - < 0.01 1.00E00 1.00E00 myeloid cell development (GO:0061515) 80 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of cellular response to transforming growth factor beta stimulus (GO:1903846) 31 0 .01 - < 0.01 1.00E00 1.00E00 endocrine system development (GO:0035270) 130 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of cellular response to transforming growth factor beta stimulus (GO:1903845) 4 0 .00 - < 0.01 1.00E00 1.00E00 interleukin-34-mediated signaling pathway (GO:0061514) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular response to transforming growth factor beta stimulus (GO:1903844) 147 0 .04 - < 0.01 1.00E00 1.00E00 protein localization to cilium (GO:0061512) 66 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to arsenite ion (GO:1903843) 3 0 .00 - < 0.01 1.00E00 1.00E00 inorganic anion transport (GO:0015698) 162 0 .05 - < 0.01 1.00E00 1.00E00 response to arsenite ion (GO:1903842) 3 0 .00 - < 0.01 1.00E00 1.00E00 centriole elongation (GO:0061511) 4 0 .00 - < 0.01 1.00E00 1.00E00 quaternary ammonium group transport (GO:0015697) 17 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to arsenite(3-) (GO:1903841) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to arsenite(3-) (GO:1903840) 1 0 .00 - < 0.01 1.00E00 1.00E00 organic cation transport (GO:0015695) 97 0 .03 - < 0.01 1.00E00 1.00E00 mercury ion transport (GO:0015694) 1 0 .00 - < 0.01 1.00E00 1.00E00 magnesium ion transport (GO:0015693) 21 0 .01 - < 0.01 1.00E00 1.00E00 lead ion transport (GO:0015692) 1 0 .00 - < 0.01 1.00E00 1.00E00 cadmium ion transport (GO:0015691) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein O-linked mannosylation (GO:0035269) 19 0 .01 - < 0.01 1.00E00 1.00E00 protein mannosylation (GO:0035268) 21 0 .01 - < 0.01 1.00E00 1.00E00 organ growth (GO:0035265) 102 1 .03 + 33.63 2.94E-02 1.00E00 multicellular organism growth (GO:0035264) 104 0 .03 - < 0.01 1.00E00 1.00E00 gonad morphogenesis (GO:0035262) 2 0 .00 - < 0.01 1.00E00 1.00E00 external genitalia morphogenesis (GO:0035261) 1 0 .00 - < 0.01 1.00E00 1.00E00 early endosome to recycling endosome transport (GO:0061502) 5 0 .00 - < 0.01 1.00E00 1.00E00 molybdate ion transport (GO:0015689) 1 0 .00 - < 0.01 1.00E00 1.00E00 magnesium ion transmembrane transport (GO:1903830) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization (GO:1903829) 495 0 .14 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization (GO:1903828) 217 0 .06 - < 0.01 1.00E00 1.00E00 L-arginine transmembrane transport (GO:1903826) 15 0 .00 - < 0.01 1.00E00 1.00E00 organic acid transmembrane transport (GO:1903825) 143 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of telomere single strand break repair (GO:1903824) 1 0 .00 - < 0.01 1.00E00 1.00E00 plasma membrane copper ion transport (GO:0015679) 2 0 .00 - < 0.01 1.00E00 1.00E00 copper ion import (GO:0015677) 7 0 .00 - < 0.01 1.00E00 1.00E00 vanadium ion transport (GO:0015676) 1 0 .00 - < 0.01 1.00E00 1.00E00 nickel cation transport (GO:0015675) 2 0 .00 - < 0.01 1.00E00 1.00E00 silver ion transport (GO:0015673) 1 0 .00 - < 0.01 1.00E00 1.00E00 oxygen transport (GO:0015671) 14 0 .00 - < 0.01 1.00E00 1.00E00 carbon dioxide transport (GO:0015670) 14 0 .00 - < 0.01 1.00E00 1.00E00 synaptic transmission, glutamatergic (GO:0035249) 48 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-arginine omega-N-methylation (GO:0035247) 1 0 .00 - < 0.01 1.00E00 1.00E00 peptidyl-arginine N-methylation (GO:0035246) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of voltage-gated potassium channel activity (GO:1903818) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of voltage-gated potassium channel activity (GO:1903817) 10 0 .00 - < 0.01 1.00E00 1.00E00 gas transport (GO:0015669) 21 0 .01 - < 0.01 1.00E00 1.00E00 L-serine import across plasma membrane (GO:1903812) 3 0 .00 - < 0.01 1.00E00 1.00E00 L-asparagine import across plasma membrane (GO:1903811) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine import across plasma membrane (GO:1903810) 2 0 .00 - < 0.01 1.00E00 1.00E00 tube morphogenesis (GO:0035239) 695 0 .20 - < 0.01 1.00E00 1.00E00 vitamin A biosynthetic process (GO:0035238) 1 0 .00 - < 0.01 1.00E00 1.00E00 ionotropic glutamate receptor signaling pathway (GO:0035235) 30 0 .01 - < 0.01 1.00E00 1.00E00 ectopic germ cell programmed cell death (GO:0035234) 18 0 .01 - < 0.01 1.00E00 1.00E00 L-isoleucine import across plasma membrane (GO:1903806) 1 0 .00 - < 0.01 1.00E00 1.00E00 glycine import across plasma membrane (GO:1903804) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-glutamine import across plasma membrane (GO:1903803) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-leucine import across plasma membrane (GO:1903801) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA processing (GO:1903800) 5 0 .00 - < 0.01 1.00E00 1.00E00 neuron-glial cell signaling (GO:0150099) 5 0 .00 - < 0.01 1.00E00 1.00E00 glial cell-neuron signaling (GO:0150098) 4 0 .00 - < 0.01 1.00E00 1.00E00 amyloid-beta clearance by cellular catabolic process (GO:0150094) 8 0 .00 - < 0.01 1.00E00 1.00E00 amyloid-beta clearance by transcytosis (GO:0150093) 7 0 .00 - < 0.01 1.00E00 1.00E00 multiple spine synapse organization, single dendrite (GO:0150090) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell competition in a multicellular organism (GO:0035212) 1 0 .00 - < 0.01 1.00E00 1.00E00 multiple spine synapse organization (GO:0150089) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuroinflammatory response (GO:0150079) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuroinflammatory response (GO:0150078) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuroinflammatory response (GO:0150077) 37 0 .01 - < 0.01 1.00E00 1.00E00 neuroinflammatory response (GO:0150076) 53 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of protein-glutamine gamma-glutamyltransferase activity (GO:0150074) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of arginase activity (GO:0150072) 1 0 .00 - < 0.01 1.00E00 1.00E00 transport of virus (GO:0046794) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of deacetylase activity (GO:0150065) 1 0 .00 - < 0.01 1.00E00 1.00E00 vertebrate eye-specific patterning (GO:0150064) 3 0 .00 - < 0.01 1.00E00 1.00E00 visual system development (GO:0150063) 410 0 .12 - < 0.01 1.00E00 1.00E00 complement-mediated synapse pruning (GO:0150062) 4 0 .00 - < 0.01 1.00E00 1.00E00 amylin receptor 3 signaling pathway (GO:0150061) 3 0 .00 - < 0.01 1.00E00 1.00E00 amylin receptor 2 signaling pathway (GO:0150060) 4 0 .00 - < 0.01 1.00E00 1.00E00 microtubule polymerization (GO:0046785) 46 0 .01 - < 0.01 1.00E00 1.00E00 regulation of viral transcription (GO:0046782) 20 0 .01 - < 0.01 1.00E00 1.00E00 amylin receptor 1 signaling pathway (GO:0150059) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic neurotransmitter receptor diffusion trapping (GO:0150054) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynapse assembly (GO:0150052) 43 0 .01 - < 0.01 1.00E00 1.00E00 protein autophosphorylation (GO:0046777) 142 0 .04 - < 0.01 1.00E00 1.00E00 regulation of synaptic signaling by nitric oxide (GO:0150045) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic dense core vesicle exocytosis (GO:0150044) 1 0 .00 - < 0.01 1.00E00 1.00E00 viral budding from plasma membrane (GO:0046761) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium-dependent activation of synaptic vesicle fusion (GO:0150037) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of trans-synaptic signaling by endocannabinoid, modulating synaptic transmission (GO:0150036) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of trans-synaptic signaling by BDNF, modulating synaptic transmission (GO:0150035) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to lysosome (GO:0150033) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to lysosome (GO:0150032) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to lysosome (GO:0150031) 5 0 .00 - < 0.01 1.00E00 1.00E00 viral budding (GO:0046755) 25 0 .01 - < 0.01 1.00E00 1.00E00 viral exocytosis (GO:0046754) 1 0 .00 - < 0.01 1.00E00 1.00E00 non-lytic viral release (GO:0046753) 15 0 .00 - < 0.01 1.00E00 1.00E00 modified amino acid biosynthetic process (GO:0042398) 40 0 .01 - < 0.01 1.00E00 1.00E00 phosphagen biosynthetic process (GO:0042396) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane potential (GO:0042391) 453 0 .13 - < 0.01 1.00E00 1.00E00 oxidised low-density lipoprotein particle clearance (GO:0150024) 1 0 .00 - < 0.01 1.00E00 1.00E00 apical dendrite arborization (GO:0150023) 1 0 .00 - < 0.01 1.00E00 1.00E00 apical dendrite development (GO:0150022) 1 0 .00 - < 0.01 1.00E00 1.00E00 apical dendrite morphogenesis (GO:0150021) 1 0 .00 - < 0.01 1.00E00 1.00E00 basal dendrite arborization (GO:0150020) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of transcytosis (GO:1904298) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ERAD pathway (GO:1904294) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ERAD pathway (GO:1904293) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ERAD pathway (GO:1904292) 26 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to non-motile cilium (GO:0097499) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic DNA damage checkpoint (GO:1904291) 1 0 .00 - < 0.01 1.00E00 1.00E00 endothelial tube lumen extension (GO:0097498) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic DNA damage checkpoint (GO:1904290) 1 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell delamination (GO:0097497) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vesicle size (GO:0097494) 18 0 .01 - < 0.01 1.00E00 1.00E00 response to histamine (GO:0034776) 11 0 .00 - < 0.01 1.00E00 1.00E00 sympathetic neuron axon guidance (GO:0097492) 4 0 .00 - < 0.01 1.00E00 1.00E00 glutathione transmembrane transport (GO:0034775) 8 0 .00 - < 0.01 1.00E00 1.00E00 sympathetic neuron projection guidance (GO:0097491) 4 0 .00 - < 0.01 1.00E00 1.00E00 sympathetic neuron projection extension (GO:0097490) 6 0 .00 - < 0.01 1.00E00 1.00E00 basal dendrite morphogenesis (GO:0150019) 3 0 .00 - < 0.01 1.00E00 1.00E00 basal dendrite development (GO:0150018) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of neuron projection arborization (GO:0150013) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neuron projection arborization (GO:0150012) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuron projection arborization (GO:0150011) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic DNA damage checkpoint (GO:1904289) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:1904283) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:1904282) 1 0 .00 - < 0.01 1.00E00 1.00E00 basement membrane disassembly (GO:0034769) 3 0 .00 - < 0.01 1.00E00 1.00E00 neuron projection guidance (GO:0097485) 229 0 .07 - < 0.01 1.00E00 1.00E00 vitamin K catabolic process (GO:0042377) 6 0 .00 - < 0.01 1.00E00 1.00E00 dendrite extension (GO:0097484) 10 0 .00 - < 0.01 1.00E00 1.00E00 phylloquinone catabolic process (GO:0042376) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of monoatomic ion transmembrane transport (GO:0034767) 146 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of monoatomic ion transmembrane transport (GO:0034766) 80 0 .02 - < 0.01 1.00E00 1.00E00 phylloquinone metabolic process (GO:0042374) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of monoatomic ion transmembrane transport (GO:0034765) 319 0 .09 - < 0.01 1.00E00 1.00E00 vitamin K metabolic process (GO:0042373) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transmembrane transport (GO:0034764) 205 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of transmembrane transport (GO:0034763) 110 0 .03 - < 0.01 1.00E00 1.00E00 regulation of transmembrane transport (GO:0034762) 437 0 .13 - < 0.01 1.00E00 1.00E00 vitamin K biosynthetic process (GO:0042371) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of iron ion transmembrane transport (GO:0034761) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion transmembrane transport (GO:0034760) 3 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-dependent synaptic vesicle endocytosis (GO:0150007) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spontaneous synaptic transmission (GO:0150003) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation by virus of viral protein levels in host cell (GO:0046726) 4 0 .00 - < 0.01 1.00E00 1.00E00 tricellular tight junction assembly (GO:1904274) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation by virus of viral protein levels in host cell (GO:0046725) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-alanine import across plasma membrane (GO:1904273) 4 0 .00 - < 0.01 1.00E00 1.00E00 oxalic acid secretion (GO:0046724) 2 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle localization (GO:0097479) 51 0 .01 - < 0.01 1.00E00 1.00E00 L-proline import across plasma membrane (GO:1904271) 3 0 .00 - < 0.01 1.00E00 1.00E00 lactic acid secretion (GO:0046722) 1 0 .00 - < 0.01 1.00E00 1.00E00 pyroptosome complex assembly (GO:1904270) 2 0 .00 - < 0.01 1.00E00 1.00E00 lateral motor column neuron migration (GO:0097477) 3 0 .00 - < 0.01 1.00E00 1.00E00 citric acid secretion (GO:0046720) 1 0 .00 - < 0.01 1.00E00 1.00E00 vitamin D catabolic process (GO:0042369) 4 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord motor neuron migration (GO:0097476) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of iron ion transmembrane transport (GO:0034759) 5 0 .00 - < 0.01 1.00E00 1.00E00 vitamin D biosynthetic process (GO:0042368) 5 0 .00 - < 0.01 1.00E00 1.00E00 motor neuron migration (GO:0097475) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of iron ion transport (GO:0034758) 2 0 .00 - < 0.01 1.00E00 1.00E00 retinal cone cell apoptotic process (GO:0097474) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of iron ion transport (GO:0034757) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of iron ion transport (GO:0034756) 8 0 .00 - < 0.01 1.00E00 1.00E00 retinal rod cell apoptotic process (GO:0097473) 2 0 .00 - < 0.01 1.00E00 1.00E00 water-soluble vitamin catabolic process (GO:0042365) 2 0 .00 - < 0.01 1.00E00 1.00E00 water-soluble vitamin biosynthetic process (GO:0042364) 9 0 .00 - < 0.01 1.00E00 1.00E00 iron ion transmembrane transport (GO:0034755) 18 0 .01 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin catabolic process (GO:0042363) 14 0 .00 - < 0.01 1.00E00 1.00E00 fat-soluble vitamin biosynthetic process (GO:0042362) 8 0 .00 - < 0.01 1.00E00 1.00E00 menaquinone catabolic process (GO:0042361) 5 0 .00 - < 0.01 1.00E00 1.00E00 vitamin E metabolic process (GO:0042360) 6 0 .00 - < 0.01 1.00E00 1.00E00 membrane disassembly (GO:0030397) 13 0 .00 - < 0.01 1.00E00 1.00E00 fructoselysine metabolic process (GO:0030393) 1 0 .00 - < 0.01 1.00E00 1.00E00 fructosamine catabolic process (GO:0030392) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation by virus of viral protein levels in host cell (GO:0046719) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell chemotaxis (GO:1904268) 1 0 .00 - < 0.01 1.00E00 1.00E00 symbiont entry into host cell (GO:0046718) 114 0 .03 - < 0.01 1.00E00 1.00E00 acid secretion (GO:0046717) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell chemotaxis (GO:1904266) 1 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell cellular homeostasis (GO:0046716) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of TORC1 signaling (GO:1904263) 55 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of TORC1 signaling (GO:1904262) 51 0 .01 - < 0.01 1.00E00 1.00E00 borate transport (GO:0046713) 1 0 .00 - < 0.01 1.00E00 1.00E00 GDP catabolic process (GO:0046712) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of basement membrane assembly involved in embryonic body morphogenesis (GO:1904261) 5 0 .00 - < 0.01 1.00E00 1.00E00 programmed cell death in response to reactive oxygen species (GO:0097468) 4 0 .00 - < 0.01 1.00E00 1.00E00 GDP biosynthetic process (GO:0046711) 1 0 .00 - < 0.01 1.00E00 1.00E00 GDP metabolic process (GO:0046710) 11 0 .00 - < 0.01 1.00E00 1.00E00 vitamin D metabolic process (GO:0042359) 15 0 .00 - < 0.01 1.00E00 1.00E00 ubiquitin-dependent glycoprotein ERAD pathway (GO:0097466) 4 0 .00 - < 0.01 1.00E00 1.00E00 thiamine diphosphate metabolic process (GO:0042357) 5 0 .00 - < 0.01 1.00E00 1.00E00 L-fucose catabolic process (GO:0042355) 10 1 .00 + > 100 2.91E-03 1.00E00 L-fucose metabolic process (GO:0042354) 10 1 .00 + > 100 2.91E-03 1.00E00 GDP-L-fucose salvage (GO:0042352) 2 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' GDP-L-fucose biosynthetic process (GO:0042351) 3 0 .00 - < 0.01 1.00E00 1.00E00 GDP-L-fucose biosynthetic process (GO:0042350) 5 0 .00 - < 0.01 1.00E00 1.00E00 fructosamine metabolic process (GO:0030389) 2 0 .00 - < 0.01 1.00E00 1.00E00 fructose 1,6-bisphosphate metabolic process (GO:0030388) 8 0 .00 - < 0.01 1.00E00 1.00E00 sperm mitochondrion organization (GO:0030382) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of basement membrane assembly involved in embryonic body morphogenesis (GO:1904259) 5 0 .00 - < 0.01 1.00E00 1.00E00 zinc ion import into Golgi lumen (GO:1904257) 3 0 .00 - < 0.01 1.00E00 1.00E00 CDP biosynthetic process (GO:0046705) 2 0 .00 - < 0.01 1.00E00 1.00E00 CDP metabolic process (GO:0046704) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of bile acid metabolic process (GO:1904253) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bile acid metabolic process (GO:1904252) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of bile acid metabolic process (GO:1904251) 14 0 .00 - < 0.01 1.00E00 1.00E00 keratan sulfate proteoglycan catabolic process (GO:0042340) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peptidyl-threonine phosphorylation (GO:0010799) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of polynucleotide adenylyltransferase activity (GO:1904247) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of polynucleotide adenylyltransferase activity (GO:1904246) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ubiquinone biosynthetic process (GO:0010795) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA export from nucleus (GO:0010793) 7 0 .00 - < 0.01 1.00E00 1.00E00 DNA double-strand break processing involved in repair via single-strand annealing (GO:0010792) 6 0 .00 - < 0.01 1.00E00 1.00E00 monoterpenoid metabolic process (GO:0016098) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly (GO:1904240) 1 0 .00 - < 0.01 1.00E00 1.00E00 keratan sulfate proteoglycan metabolic process (GO:0042339) 18 0 .01 - < 0.01 1.00E00 1.00E00 polyprenol catabolic process (GO:0016095) 3 0 .00 - < 0.01 1.00E00 1.00E00 polyprenol biosynthetic process (GO:0016094) 4 0 .00 - < 0.01 1.00E00 1.00E00 nucleosome organization (GO:0034728) 110 0 .03 - < 0.01 1.00E00 1.00E00 polyprenol metabolic process (GO:0016093) 10 0 .00 - < 0.01 1.00E00 1.00E00 piecemeal microautophagy of the nucleus (GO:0034727) 18 0 .01 - < 0.01 1.00E00 1.00E00 cuticle development (GO:0042335) 3 0 .00 - < 0.01 1.00E00 1.00E00 taxis (GO:0042330) 344 0 .10 - < 0.01 1.00E00 1.00E00 meiotic sister chromatid cohesion involved in meiosis I (GO:0010789) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly (GO:1904239) 1 0 .00 - < 0.01 1.00E00 1.00E00 pericyte cell differentiation (GO:1904238) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of substrate-dependent cell migration, cell attachment to substrate (GO:1904237) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of substrate-dependent cell migration, cell attachment to substrate (GO:1904235) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of aconitate hydratase activity (GO:1904234) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of succinate dehydrogenase activity (GO:1904231) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break formation involved in reciprocal meiotic recombination (GO:0010780) 1 0 .00 - < 0.01 1.00E00 1.00E00 supramolecular fiber organization (GO:0097435) 609 0 .18 - < 0.01 1.00E00 1.00E00 positive regulation of phosphorylation (GO:0042327) 335 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of phosphorylation (GO:0042326) 174 0 .05 - < 0.01 1.00E00 1.00E00 synaptic vesicle priming (GO:0016082) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phosphorylation (GO:0042325) 559 0 .16 - < 0.01 1.00E00 1.00E00 synaptic vesicle docking (GO:0016081) 12 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle targeting (GO:0016080) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, non-REM sleep (GO:0042323) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, REM sleep (GO:0042322) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of circadian sleep/wake cycle, sleep (GO:0042321) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of circadian sleep/wake cycle, REM sleep (GO:0042320) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of succinate dehydrogenase activity (GO:1904229) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen synthase activity, transferring glucose-1-phosphate (GO:1904227) 1 0 .00 - < 0.01 1.00E00 1.00E00 meiotic strand invasion involved in reciprocal meiotic recombination (GO:0010774) 1 0 .00 - < 0.01 1.00E00 1.00E00 synaptic vesicle exocytosis (GO:0016079) 64 0 .02 - < 0.01 1.00E00 1.00E00 tRNA decay (GO:0016078) 13 0 .00 - < 0.01 1.00E00 1.00E00 sno(s)RNA catabolic process (GO:0016077) 3 0 .00 - < 0.01 1.00E00 1.00E00 snRNA catabolic process (GO:0016076) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell morphogenesis (GO:0010770) 36 0 .01 - < 0.01 1.00E00 1.00E00 rRNA catabolic process (GO:0016075) 16 0 .00 - < 0.01 1.00E00 1.00E00 sno(s)RNA metabolic process (GO:0016074) 16 0 .00 - < 0.01 1.00E00 1.00E00 snRNA metabolic process (GO:0016073) 56 0 .02 - < 0.01 1.00E00 1.00E00 rRNA metabolic process (GO:0016072) 250 0 .07 - < 0.01 1.00E00 1.00E00 mRNA metabolic process (GO:0016071) 618 0 .18 - < 0.01 1.00E00 1.00E00 RNA metabolic process (GO:0016070) 1537 0 .45 - < 0.01 1.00E00 1.00E00 liver regeneration (GO:0097421) 31 0 .01 - < 0.01 1.00E00 1.00E00 protein kinase C deactivation (GO:0042313) 1 0 .00 - < 0.01 1.00E00 1.00E00 vasodilation (GO:0042311) 57 0 .02 - < 0.01 1.00E00 1.00E00 vasoconstriction (GO:0042310) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of sodium ion transport (GO:0010766) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sodium ion transport (GO:0010765) 36 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fibroblast migration (GO:0010764) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fibroblast migration (GO:0010763) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fibroblast migration (GO:0010762) 38 0 .01 - < 0.01 1.00E00 1.00E00 type I hypersensitivity (GO:0016068) 2 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast migration (GO:0010761) 20 0 .01 - < 0.01 1.00E00 1.00E00 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol (GO:1904211) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage chemotaxis (GO:0010760) 7 1 .00 + > 100 2.04E-03 1.00E00 homoiothermy (GO:0042309) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein import into nucleus (GO:0042308) 17 0 .00 - < 0.01 1.00E00 1.00E00 immunoglobulin mediated immune response (GO:0016064) 184 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of protein import into nucleus (GO:0042307) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein import into nucleus (GO:0042306) 63 0 .02 - < 0.01 1.00E00 1.00E00 regulation of fatty acid biosynthetic process (GO:0042304) 44 0 .01 - < 0.01 1.00E00 1.00E00 molting cycle (GO:0042303) 100 0 .03 - < 0.01 1.00E00 1.00E00 hypoxia-inducible factor-1alpha signaling pathway (GO:0097411) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell migration (GO:0030336) 297 1 .09 + 11.55 8.35E-02 1.00E00 positive regulation of cell migration (GO:0030335) 557 0 .16 - < 0.01 1.00E00 1.00E00 regulation of cell migration (GO:0030334) 961 1 .28 + 3.57 2.49E-01 1.00E00 DNA damage response, signal transduction by p53 class mediator (GO:0030330) 42 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage chemotaxis (GO:0010759) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of macrophage chemotaxis (GO:0010758) 30 1 .01 + > 100 8.72E-03 1.00E00 negative regulation of plasminogen activation (GO:0010757) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of plasminogen activation (GO:0010756) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle hypertrophy (GO:1904206) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasminogen activation (GO:0010755) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle hypertrophy (GO:1904205) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cGMP-mediated signaling (GO:0010754) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle hypertrophy (GO:1904204) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cGMP-mediated signaling (GO:0010753) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cGMP-mediated signaling (GO:0010752) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nitric oxide mediated signal transduction (GO:0010751) 2 0 .00 - < 0.01 1.00E00 1.00E00 G protein-coupled opsin signaling pathway (GO:0016056) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nitric oxide mediated signal transduction (GO:0010750) 4 0 .00 - < 0.01 1.00E00 1.00E00 iodide transmembrane transport (GO:1904200) 2 0 .00 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway (GO:0016055) 282 0 .08 - < 0.01 1.00E00 1.00E00 organic acid catabolic process (GO:0016054) 225 0 .07 - < 0.01 1.00E00 1.00E00 organic acid biosynthetic process (GO:0016053) 276 0 .08 - < 0.01 1.00E00 1.00E00 carbohydrate catabolic process (GO:0016052) 124 1 .04 + 27.66 3.56E-02 1.00E00 carbohydrate biosynthetic process (GO:0016051) 123 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to raffinose (GO:0097403) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast migration (GO:0097402) 6 0 .00 - < 0.01 1.00E00 1.00E00 vesicle organization (GO:0016050) 355 0 .10 - < 0.01 1.00E00 1.00E00 synaptic vesicle lumen acidification (GO:0097401) 18 0 .01 - < 0.01 1.00E00 1.00E00 interleukin-17-mediated signaling pathway (GO:0097400) 9 0 .00 - < 0.01 1.00E00 1.00E00 prenylcysteine metabolic process (GO:0030329) 2 0 .00 - < 0.01 1.00E00 1.00E00 prenylcysteine catabolic process (GO:0030328) 2 0 .00 - < 0.01 1.00E00 1.00E00 prenylated protein catabolic process (GO:0030327) 3 0 .00 - < 0.01 1.00E00 1.00E00 embryonic limb morphogenesis (GO:0030326) 124 0 .04 - < 0.01 1.00E00 1.00E00 adrenal gland development (GO:0030325) 28 0 .01 - < 0.01 1.00E00 1.00E00 lung development (GO:0030324) 193 0 .06 - < 0.01 1.00E00 1.00E00 respiratory tube development (GO:0030323) 197 0 .06 - < 0.01 1.00E00 1.00E00 stabilization of membrane potential (GO:0030322) 3 0 .00 - < 0.01 1.00E00 1.00E00 transepithelial chloride transport (GO:0030321) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitric oxide mediated signal transduction (GO:0010749) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of long-chain fatty acid import across plasma membrane (GO:0010748) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of long-chain fatty acid import across plasma membrane (GO:0010747) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of long-chain fatty acid import across plasma membrane (GO:0010746) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macrophage derived foam cell differentiation (GO:0010745) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage derived foam cell differentiation (GO:0010744) 20 0 .01 - < 0.01 1.00E00 1.00E00 cell growth (GO:0016049) 116 0 .03 - < 0.01 1.00E00 1.00E00 regulation of macrophage derived foam cell differentiation (GO:0010743) 33 0 .01 - < 0.01 1.00E00 1.00E00 detection of temperature stimulus (GO:0016048) 29 0 .01 - < 0.01 1.00E00 1.00E00 macrophage derived foam cell differentiation (GO:0010742) 5 0 .00 - < 0.01 1.00E00 1.00E00 detection of fungus (GO:0016046) 3 0 .00 - < 0.01 1.00E00 1.00E00 detection of bacterium (GO:0016045) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular component organization (GO:0016043) 5872 1 1.71 - .58 1.00E00 1.00E00 melanocyte differentiation (GO:0030318) 21 0 .01 - < 0.01 1.00E00 1.00E00 flagellated sperm motility (GO:0030317) 180 0 .05 - < 0.01 1.00E00 1.00E00 osteoclast differentiation (GO:0030316) 60 0 .02 - < 0.01 1.00E00 1.00E00 poly-N-acetyllactosamine biosynthetic process (GO:0030311) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein kinase A signaling (GO:0010739) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein kinase A signaling (GO:0010738) 8 0 .00 - < 0.01 1.00E00 1.00E00 protein kinase A signaling (GO:0010737) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein glutathionylation (GO:0010734) 1 0 .00 - < 0.01 1.00E00 1.00E00 absorption of visible light (GO:0016038) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein glutathionylation (GO:0010732) 1 0 .00 - < 0.01 1.00E00 1.00E00 light absorption (GO:0016037) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to phosphate starvation (GO:0016036) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide biosynthetic process (GO:0010730) 3 0 .00 - < 0.01 1.00E00 1.00E00 memory T cell proliferation (GO:0061485) 1 0 .00 - < 0.01 1.00E00 1.00E00 hematopoietic stem cell homeostasis (GO:0061484) 24 0 .01 - < 0.01 1.00E00 1.00E00 viral process (GO:0016032) 265 0 .08 - < 0.01 1.00E00 1.00E00 tRNA import into mitochondrion (GO:0016031) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to TNF agonist (GO:0061481) 1 0 .00 - < 0.01 1.00E00 1.00E00 poly-N-acetyllactosamine metabolic process (GO:0030309) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell growth (GO:0030308) 170 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of cell growth (GO:0030307) 160 0 .05 - < 0.01 1.00E00 1.00E00 deoxynucleotide transport (GO:0030302) 1 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol transport (GO:0030301) 67 0 .02 - < 0.01 1.00E00 1.00E00 regulation of intestinal cholesterol absorption (GO:0030300) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide biosynthetic process (GO:0010729) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide biosynthetic process (GO:0010728) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide metabolic process (GO:0010727) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of hydrogen peroxide metabolic process (GO:0010726) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of primitive erythrocyte differentiation (GO:0010725) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of definitive erythrocyte differentiation (GO:0010724) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ferrochelatase activity (GO:0010722) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell development (GO:0010721) 273 0 .08 - < 0.01 1.00E00 1.00E00 positive regulation of cell development (GO:0010720) 440 0 .13 - < 0.01 1.00E00 1.00E00 CDP-diacylglycerol biosynthetic process (GO:0016024) 13 0 .00 - < 0.01 1.00E00 1.00E00 T follicular helper cell differentiation (GO:0061470) 11 0 .00 - < 0.01 1.00E00 1.00E00 PKR/eIFalpha signaling (GO:0039585) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial to mesenchymal transition (GO:0010719) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial to mesenchymal transition (GO:0010718) 56 0 .02 - < 0.01 1.00E00 1.00E00 regulation of epithelial to mesenchymal transition (GO:0010717) 107 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of extracellular matrix disassembly (GO:0010716) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extracellular matrix disassembly (GO:0010715) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of collagen metabolic process (GO:0010714) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of collagen metabolic process (GO:0010713) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type B pancreatic cell proliferation (GO:0061469) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collagen metabolic process (GO:0010712) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA processing (GO:1903799) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of collagen catabolic process (GO:0010711) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of miRNA processing (GO:1903798) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collagen catabolic process (GO:0010710) 4 0 .00 - < 0.01 1.00E00 1.00E00 gonad development (GO:0008406) 232 1 .07 + 14.78 6.58E-02 1.00E00 positive regulation of inorganic anion transmembrane transport (GO:1903797) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inorganic anion transmembrane transport (GO:1903796) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inorganic anion transmembrane transport (GO:1903795) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to lysosome (GO:0061462) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of monoatomic anion transport (GO:1903793) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of monoatomic anion transport (GO:1903792) 4 0 .00 - < 0.01 1.00E00 1.00E00 uracil transmembrane transport (GO:1903791) 3 0 .00 - < 0.01 1.00E00 1.00E00 guanine nucleotide transmembrane transport (GO:1903790) 9 0 .00 - < 0.01 1.00E00 1.00E00 glycolysis from storage polysaccharide through glucose-1-phosphate (GO:0093001) 1 0 .00 - < 0.01 1.00E00 1.00E00 globoside biosynthetic process via lactosylceramide (GO:0010707) 1 0 .00 - < 0.01 1.00E00 1.00E00 ganglioside biosynthetic process via lactosylceramide (GO:0010706) 6 0 .00 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination (GO:0010705) 2 0 .00 - < 0.01 1.00E00 1.00E00 reproductive system development (GO:0061458) 309 1 .09 + 11.10 8.68E-02 1.00E00 positive regulation of norepinephrine secretion (GO:0010701) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amino acid transmembrane transport (GO:1903789) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of norepinephrine secretion (GO:0010700) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glutathione biosynthetic process (GO:1903788) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glutathione biosynthetic process (GO:1903786) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-valine transmembrane transport (GO:1903785) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sodium ion import across plasma membrane (GO:1903783) 1 0 .00 - < 0.01 1.00E00 1.00E00 retrotrapezoid nucleus neuron differentiation (GO:0061452) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sodium ion import across plasma membrane (GO:1903782) 1 0 .00 - < 0.01 1.00E00 1.00E00 retrotrapezoid nucleus development (GO:0061451) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac conduction (GO:1903781) 1 0 .00 - < 0.01 1.00E00 1.00E00 trophoblast cell migration (GO:0061450) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac conduction (GO:1903780) 1 0 .00 - < 0.01 1.00E00 1.00E00 charged-tRNA amino acid modification (GO:0019988) 2 0 .00 - < 0.01 1.00E00 1.00E00 connective tissue development (GO:0061448) 235 1 .07 + 14.60 6.66E-02 1.00E00 regulation of cardiac conduction (GO:1903779) 25 0 .01 - < 0.01 1.00E00 1.00E00 translesion synthesis (GO:0019985) 25 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to vacuolar membrane (GO:1903778) 1 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion cell fate commitment (GO:0061445) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA double-strand break processing (GO:1903775) 1 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion cell development (GO:0061444) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of viral budding via host ESCRT complex (GO:1903774) 3 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion cell differentiation (GO:0061443) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of viral budding via host ESCRT complex (GO:1903772) 3 0 .00 - < 0.01 1.00E00 1.00E00 renal artery morphogenesis (GO:0061441) 2 0 .00 - < 0.01 1.00E00 1.00E00 kidney vasculature development (GO:0061440) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of beta-galactosidase activity (GO:1903771) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of beta-galactosidase activity (GO:1903770) 1 0 .00 - < 0.01 1.00E00 1.00E00 miRNA processing (GO:0035196) 34 0 .01 - < 0.01 1.00E00 1.00E00 kidney vasculature morphogenesis (GO:0061439) 8 0 .00 - < 0.01 1.00E00 1.00E00 miRNA-mediated post-transcriptional gene silencing (GO:0035195) 28 0 .01 - < 0.01 1.00E00 1.00E00 renal system vasculature morphogenesis (GO:0061438) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulatory ncRNA-mediated post-transcriptional gene silencing (GO:0035194) 39 0 .01 - < 0.01 1.00E00 1.00E00 renal system vasculature development (GO:0061437) 24 0 .01 - < 0.01 1.00E00 1.00E00 establishment of skin barrier (GO:0061436) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of potassium ion export across plasma membrane (GO:1903766) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of potassium ion export across plasma membrane (GO:1903765) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to caloric restriction (GO:0061433) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of potassium ion export across plasma membrane (GO:1903764) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to methionine (GO:0061431) 5 0 .00 - < 0.01 1.00E00 1.00E00 bone trabecula morphogenesis (GO:0061430) 12 0 .00 - < 0.01 1.00E00 1.00E00 hatching (GO:0035188) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of SUMO transferase activity (GO:1903755) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of p38MAPK cascade (GO:1903753) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:1903751) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide (GO:1903750) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of RIG-I signaling pathway (GO:0039536) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of RIG-I signaling pathway (GO:0039535) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of MDA-5 signaling pathway (GO:0039534) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of MDA-5 signaling pathway (GO:0039533) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic pattern recognition receptor signaling pathway (GO:0039532) 60 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cytoplasmic pattern recognition receptor signaling pathway (GO:0039531) 129 0 .04 - < 0.01 1.00E00 1.00E00 MDA-5 signaling pathway (GO:0039530) 4 0 .00 - < 0.01 1.00E00 1.00E00 social behavior (GO:0035176) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of establishment of protein localization to mitochondrion (GO:1903749) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of establishment of protein localization to mitochondrion (GO:1903748) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of protein localization to mitochondrion (GO:1903747) 52 0 .02 - < 0.01 1.00E00 1.00E00 sexual reproduction (GO:0019953) 1088 0 .32 - < 0.01 1.00E00 1.00E00 positive regulation of anterograde synaptic vesicle transport (GO:1903744) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anterograde synaptic vesicle transport (GO:1903742) 2 0 .00 - < 0.01 1.00E00 1.00E00 RIG-I signaling pathway (GO:0039529) 7 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic hemopoiesis (GO:0035166) 5 0 .00 - < 0.01 1.00E00 1.00E00 embryonic hemopoiesis (GO:0035162) 23 0 .01 - < 0.01 1.00E00 1.00E00 modification-dependent protein catabolic process (GO:0019941) 561 0 .16 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane organization (GO:1903729) 17 0 .00 - < 0.01 1.00E00 1.00E00 cGMP-mediated signaling (GO:0019934) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid metabolic process (GO:1903727) 16 0 .00 - < 0.01 1.00E00 1.00E00 cAMP-mediated signaling (GO:0019933) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid metabolic process (GO:1903726) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of tube size (GO:0035150) 159 0 .05 - < 0.01 1.00E00 1.00E00 regulation of phospholipid metabolic process (GO:1903725) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of centriole elongation (GO:1903724) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of centriole elongation (GO:1903723) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of centriole elongation (GO:1903722) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of I-kappaB phosphorylation (GO:1903721) 1 0 .00 - < 0.01 1.00E00 1.00E00 tube formation (GO:0035148) 142 0 .04 - < 0.01 1.00E00 1.00E00 regulation of I-kappaB phosphorylation (GO:1903719) 1 0 .00 - < 0.01 1.00E00 1.00E00 guanine transmembrane transport (GO:1903716) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of aerobic respiration (GO:1903715) 29 0 .01 - < 0.01 1.00E00 1.00E00 isoleucine transmembrane transport (GO:1903714) 1 0 .00 - < 0.01 1.00E00 1.00E00 asparagine transmembrane transport (GO:1903713) 2 0 .00 - < 0.01 1.00E00 1.00E00 cysteine transmembrane transport (GO:1903712) 3 0 .00 - < 0.01 1.00E00 1.00E00 spermidine transmembrane transport (GO:1903711) 4 0 .00 - < 0.01 1.00E00 1.00E00 spermine transmembrane transport (GO:1903710) 1 0 .00 - < 0.01 1.00E00 1.00E00 hindlimb morphogenesis (GO:0035137) 36 0 .01 - < 0.01 1.00E00 1.00E00 forelimb morphogenesis (GO:0035136) 41 0 .01 - < 0.01 1.00E00 1.00E00 peptidyl-arginine methylation, to symmetrical-dimethyl arginine (GO:0019918) 1 0 .00 - < 0.01 1.00E00 1.00E00 uterine gland development (GO:1903709) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipid storage (GO:0019915) 50 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of hemopoiesis (GO:1903708) 193 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of hemopoiesis (GO:1903707) 121 0 .04 - < 0.01 1.00E00 1.00E00 regulation of hemopoiesis (GO:1903706) 416 0 .12 - < 0.01 1.00E00 1.00E00 enterocyte differentiation (GO:1903703) 1 0 .00 - < 0.01 1.00E00 1.00E00 substantia propria of cornea development (GO:1903701) 2 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic hindlimb morphogenesis (GO:0035129) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic forelimb morphogenesis (GO:0035128) 2 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic limb morphogenesis (GO:0035127) 3 0 .00 - < 0.01 1.00E00 1.00E00 post-embryonic appendage morphogenesis (GO:0035120) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic spine development (GO:0060999) 41 0 .01 - < 0.01 1.00E00 1.00E00 regulation of dendritic spine development (GO:0060998) 59 0 .02 - < 0.01 1.00E00 1.00E00 dendritic spine morphogenesis (GO:0060997) 18 0 .01 - < 0.01 1.00E00 1.00E00 dendritic spine development (GO:0060996) 29 0 .01 - < 0.01 1.00E00 1.00E00 kidney morphogenesis (GO:0060993) 89 0 .03 - < 0.01 1.00E00 1.00E00 response to fungicide (GO:0060992) 7 0 .00 - < 0.01 1.00E00 1.00E00 embryonic hindlimb morphogenesis (GO:0035116) 28 0 .01 - < 0.01 1.00E00 1.00E00 embryonic forelimb morphogenesis (GO:0035115) 33 0 .01 - < 0.01 1.00E00 1.00E00 embryonic appendage morphogenesis (GO:0035113) 124 0 .04 - < 0.01 1.00E00 1.00E00 genitalia morphogenesis (GO:0035112) 12 0 .00 - < 0.01 1.00E00 1.00E00 lipid tube assembly involved in organelle fusion (GO:0060989) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipid tube assembly (GO:0060988) 3 0 .00 - < 0.01 1.00E00 1.00E00 endocrine hormone secretion (GO:0060986) 16 0 .00 - < 0.01 1.00E00 1.00E00 coronary artery morphogenesis (GO:0060982) 9 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in coronary angiogenesis (GO:0060981) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in coronary vasculogenesis (GO:0060980) 1 0 .00 - < 0.01 1.00E00 1.00E00 limb morphogenesis (GO:0035108) 152 0 .04 - < 0.01 1.00E00 1.00E00 appendage morphogenesis (GO:0035107) 152 0 .04 - < 0.01 1.00E00 1.00E00 operant conditioning (GO:0035106) 4 0 .00 - < 0.01 1.00E00 1.00E00 vasculogenesis involved in coronary vascular morphogenesis (GO:0060979) 4 0 .00 - < 0.01 1.00E00 1.00E00 angiogenesis involved in coronary vascular morphogenesis (GO:0060978) 5 0 .00 - < 0.01 1.00E00 1.00E00 coronary vasculature morphogenesis (GO:0060977) 18 0 .01 - < 0.01 1.00E00 1.00E00 coronary vasculature development (GO:0060976) 47 0 .01 - < 0.01 1.00E00 1.00E00 cardioblast migration to the midline involved in heart field formation (GO:0060975) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in heart formation (GO:0060974) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in heart development (GO:0060973) 17 0 .00 - < 0.01 1.00E00 1.00E00 left/right pattern formation (GO:0060972) 141 0 .04 - < 0.01 1.00E00 1.00E00 embryonic heart tube left/right pattern formation (GO:0060971) 6 0 .00 - < 0.01 1.00E00 1.00E00 decidualization (GO:0046697) 25 0 .01 - < 0.01 1.00E00 1.00E00 sperm competition (GO:0046692) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gene silencing by regulatory ncRNA (GO:0060967) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of gene silencing by regulatory ncRNA (GO:0060966) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA-mediated gene silencing (GO:0060965) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of miRNA-mediated gene silencing (GO:0060964) 29 0 .01 - < 0.01 1.00E00 1.00E00 response to mercury ion (GO:0046689) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to copper ion (GO:0046688) 38 0 .01 - < 0.01 1.00E00 1.00E00 response to cadmium ion (GO:0046686) 51 0 .01 - < 0.01 1.00E00 1.00E00 response to arsenic-containing substance (GO:0046685) 32 0 .01 - < 0.01 1.00E00 1.00E00 response to pyrethroid (GO:0046684) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to organophosphorus (GO:0046683) 132 0 .04 - < 0.01 1.00E00 1.00E00 endocardial cell fate commitment (GO:0060957) 1 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cell differentiation (GO:0060956) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to antibiotic (GO:0046677) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of insulin secretion (GO:0046676) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of retinal cell programmed cell death (GO:0046671) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac vascular smooth muscle cell development (GO:0060948) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac vascular smooth muscle cell differentiation (GO:0060947) 7 0 .00 - < 0.01 1.00E00 1.00E00 cardiac neuron differentiation (GO:0060945) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithelial to mesenchymal transition involved in cardiac fibroblast development (GO:0060940) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retinal cell programmed cell death (GO:0046668) 4 0 .00 - < 0.01 1.00E00 1.00E00 retinal cell programmed cell death (GO:0046666) 3 0 .00 - < 0.01 1.00E00 1.00E00 male sex differentiation (GO:0046661) 171 0 .05 - < 0.01 1.00E00 1.00E00 female sex differentiation (GO:0046660) 117 1 .03 + 29.32 3.36E-02 1.00E00 response to luteinizing hormone (GO:0034699) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to gonadotropin (GO:0034698) 28 0 .01 - < 0.01 1.00E00 1.00E00 response to prostaglandin F (GO:0034696) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to prostaglandin E (GO:0034695) 29 0 .01 - < 0.01 1.00E00 1.00E00 epicardium-derived cardiac fibroblast cell development (GO:0060939) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to prostaglandin (GO:0034694) 37 0 .01 - < 0.01 1.00E00 1.00E00 epicardium-derived cardiac fibroblast cell differentiation (GO:0060938) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac fibroblast cell development (GO:0060936) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac fibroblast cell differentiation (GO:0060935) 4 0 .00 - < 0.01 1.00E00 1.00E00 His-Purkinje system cell differentiation (GO:0060932) 4 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial node cell development (GO:0060931) 5 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial node cell fate commitment (GO:0060930) 1 0 .00 - < 0.01 1.00E00 1.00E00 folic acid catabolic process (GO:0046657) 1 0 .00 - < 0.01 1.00E00 1.00E00 folic acid metabolic process (GO:0046655) 13 0 .00 - < 0.01 1.00E00 1.00E00 tetrahydrofolate biosynthetic process (GO:0046654) 6 0 .00 - < 0.01 1.00E00 1.00E00 tetrahydrofolate metabolic process (GO:0046653) 17 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte proliferation (GO:0046651) 114 0 .03 - < 0.01 1.00E00 1.00E00 vocal learning (GO:0042297) 7 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular node cell fate commitment (GO:0060929) 2 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular node cell development (GO:0060928) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac pacemaker cell fate commitment (GO:0060927) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac pacemaker cell development (GO:0060926) 9 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell fate commitment (GO:0060923) 7 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular node cell differentiation (GO:0060922) 5 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial node cell differentiation (GO:0060921) 6 0 .00 - < 0.01 1.00E00 1.00E00 cardiac pacemaker cell differentiation (GO:0060920) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of regulation of vascular associated smooth muscle cell membrane depolarization (GO:1904199) 1 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte activation (GO:0046649) 502 0 .15 - < 0.01 1.00E00 1.00E00 positive regulation of granulosa cell proliferation (GO:1904197) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of granulosa cell proliferation (GO:1904195) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of gamma-delta T cell activation (GO:0046645) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cholangiocyte apoptotic process (GO:1904193) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gamma-delta T cell activation (GO:0046643) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholangiocyte apoptotic process (GO:1904192) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of alpha-beta T cell proliferation (GO:0046642) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to interleukin-17 (GO:0097398) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of alpha-beta T cell proliferation (GO:0046641) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of alpha-beta T cell proliferation (GO:0046640) 43 0 .01 - < 0.01 1.00E00 1.00E00 response to interleukin-17 (GO:0097396) 15 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation involved in lung development (GO:0060916) 5 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell differentiation involved in lung development (GO:0060915) 2 0 .00 - < 0.01 1.00E00 1.00E00 heart formation (GO:0060914) 18 0 .01 - < 0.01 1.00E00 1.00E00 cardiac cell fate determination (GO:0060913) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac cell fate specification (GO:0060912) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac cell fate commitment (GO:0060911) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transformation of host cell by virus (GO:1904189) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of alpha-beta T cell differentiation (GO:0046639) 30 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of transformation of host cell by virus (GO:1904188) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of alpha-beta T cell differentiation (GO:0046638) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of transformation of host cell by virus (GO:1904187) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of alpha-beta T cell differentiation (GO:0046637) 80 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of alpha-beta T cell activation (GO:0046636) 50 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of alpha-beta T cell activation (GO:0046635) 73 0 .02 - < 0.01 1.00E00 1.00E00 regulation of alpha-beta T cell activation (GO:0046634) 122 0 .04 - < 0.01 1.00E00 1.00E00 alpha-beta T cell proliferation (GO:0046633) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of pyruvate dehydrogenase activity (GO:1904182) 1 0 .00 - < 0.01 1.00E00 1.00E00 alpha-beta T cell differentiation (GO:0046632) 83 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of membrane depolarization (GO:1904181) 11 0 .00 - < 0.01 1.00E00 1.00E00 alpha-beta T cell activation (GO:0046631) 118 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of membrane depolarization (GO:1904180) 8 0 .00 - < 0.01 1.00E00 1.00E00 gamma-delta T cell proliferation (GO:0046630) 1 0 .00 - < 0.01 1.00E00 1.00E00 purine nucleoside metabolic process (GO:0042278) 27 0 .01 - < 0.01 1.00E00 1.00E00 error-prone translesion synthesis (GO:0042276) 11 0 .00 - < 0.01 1.00E00 1.00E00 ribosomal small subunit biogenesis (GO:0042274) 108 0 .03 - < 0.01 1.00E00 1.00E00 ribosomal large subunit biogenesis (GO:0042273) 68 0 .02 - < 0.01 1.00E00 1.00E00 dorsal spinal cord interneuron anterior axon guidance (GO:0097380) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage cytokine production (GO:0060907) 25 0 .01 - < 0.01 1.00E00 1.00E00 susceptibility to natural killer cell mediated cytotoxicity (GO:0042271) 3 0 .00 - < 0.01 1.00E00 1.00E00 protection from natural killer cell mediated cytotoxicity (GO:0042270) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein folding in endoplasmic reticulum (GO:0060904) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of meiosis I (GO:0060903) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic camera-type eye formation (GO:0060900) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adipose tissue development (GO:1904179) 10 0 .00 - < 0.01 1.00E00 1.00E00 gamma-delta T cell activation (GO:0046629) 20 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of adipose tissue development (GO:1904178) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of insulin receptor signaling pathway (GO:0046628) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of adipose tissue development (GO:1904177) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of insulin receptor signaling pathway (GO:0046627) 43 0 .01 - < 0.01 1.00E00 1.00E00 regulation of insulin receptor signaling pathway (GO:0046626) 70 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of bleb assembly (GO:1904172) 2 0 .00 - < 0.01 1.00E00 1.00E00 dorsal spinal cord interneuron posterior axon guidance (GO:0097379) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of organ growth (GO:0046622) 44 0 .01 - < 0.01 1.00E00 1.00E00 dorsal spinal cord interneuron axon guidance (GO:0097378) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of organ growth (GO:0046621) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of bleb assembly (GO:1904170) 2 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord interneuron axon guidance (GO:0097377) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of organ growth (GO:0046620) 88 0 .03 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell mediated cytotoxicity (GO:0042269) 52 0 .02 - < 0.01 1.00E00 1.00E00 interneuron axon guidance (GO:0097376) 4 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell mediated cytotoxicity (GO:0042267) 41 0 .01 - < 0.01 1.00E00 1.00E00 sensory neuron axon guidance (GO:0097374) 3 0 .00 - < 0.01 1.00E00 1.00E00 nucleobase-containing small molecule catabolic process (GO:0034656) 22 0 .01 - < 0.01 1.00E00 1.00E00 nucleobase-containing compound catabolic process (GO:0034655) 332 0 .10 - < 0.01 1.00E00 1.00E00 nucleobase-containing compound biosynthetic process (GO:0034654) 1771 0 .52 - < 0.01 1.00E00 1.00E00 protein O-GlcNAcylation via threonine (GO:0097370) 1 0 .00 - < 0.01 1.00E00 1.00E00 DNA protection (GO:0042262) 6 0 .00 - < 0.01 1.00E00 1.00E00 retinoic acid catabolic process (GO:0034653) 4 0 .00 - < 0.01 1.00E00 1.00E00 cortisol biosynthetic process (GO:0034651) 3 0 .00 - < 0.01 1.00E00 1.00E00 intestinal cholesterol absorption (GO:0030299) 11 0 .00 - < 0.01 1.00E00 1.00E00 cortisol metabolic process (GO:0034650) 5 0 .00 - < 0.01 1.00E00 1.00E00 lens placode formation involved in camera-type eye formation (GO:0046619) 2 0 .00 - < 0.01 1.00E00 1.00E00 xenobiotic export from cell (GO:0046618) 14 0 .00 - < 0.01 1.00E00 1.00E00 DNA synthesis involved in UV-damage excision repair (GO:1904161) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of Sertoli cell barrier (GO:0097368) 4 0 .00 - < 0.01 1.00E00 1.00E00 cytosolic ribosome assembly (GO:0042256) 9 0 .00 - < 0.01 1.00E00 1.00E00 ribosome assembly (GO:0042255) 62 0 .02 - < 0.01 1.00E00 1.00E00 ribosome biogenesis (GO:0042254) 309 0 .09 - < 0.01 1.00E00 1.00E00 cellular response to UV (GO:0034644) 89 0 .03 - < 0.01 1.00E00 1.00E00 establishment of mitochondrion localization, microtubule-mediated (GO:0034643) 25 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrion migration along actin filament (GO:0034642) 1 0 .00 - < 0.01 1.00E00 1.00E00 bone mineralization (GO:0030282) 62 0 .02 - < 0.01 1.00E00 1.00E00 axonemal central apparatus assembly (GO:1904158) 6 0 .00 - < 0.01 1.00E00 1.00E00 DN4 thymocyte differentiation (GO:1904157) 2 0 .00 - < 0.01 1.00E00 1.00E00 DN3 thymocyte differentiation (GO:1904156) 1 0 .00 - < 0.01 1.00E00 1.00E00 DN2 thymocyte differentiation (GO:1904155) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of centrosome cycle (GO:0046606) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of centrosome cycle (GO:0046605) 58 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of retrograde protein transport, ER to cytosol (GO:1904154) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic centrosome separation (GO:0046604) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of retrograde protein transport, ER to cytosol (GO:1904153) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retrograde protein transport, ER to cytosol (GO:1904152) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic centrosome separation (GO:0046603) 1 0 .00 - < 0.01 1.00E00 1.00E00 UDP-glucosylation (GO:0097359) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic centrosome separation (GO:0046602) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microglial cell mediated cytotoxicity (GO:1904151) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of centriole replication (GO:0046601) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microglial cell mediated cytotoxicity (GO:1904150) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of planar polarity of embryonic epithelium (GO:0042249) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of centriole replication (GO:0046600) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to heterochromatin (GO:0097355) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylcholine catabolic process (GO:0034638) 13 0 .00 - < 0.01 1.00E00 1.00E00 establishment of planar polarity of follicular epithelium (GO:0042247) 1 0 .00 - < 0.01 1.00E00 1.00E00 prenylation (GO:0097354) 10 0 .00 - < 0.01 1.00E00 1.00E00 tissue regeneration (GO:0042246) 69 0 .02 - < 0.01 1.00E00 1.00E00 RNA repair (GO:0042245) 3 0 .00 - < 0.01 1.00E00 1.00E00 autophagosome maturation (GO:0097352) 53 0 .02 - < 0.01 1.00E00 1.00E00 glutathione transport (GO:0034635) 10 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil clearance (GO:0097350) 6 0 .00 - < 0.01 1.00E00 1.00E00 retinol transport (GO:0034633) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of ossification (GO:0030279) 45 0 .01 - < 0.01 1.00E00 1.00E00 regulation of ossification (GO:0030278) 126 0 .04 - < 0.01 1.00E00 1.00E00 maintenance of gastrointestinal epithelium (GO:0030277) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of microglial cell mediated cytotoxicity (GO:1904149) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of alkaline phosphatase activity (GO:0010694) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of alkaline phosphatase activity (GO:0010692) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of microglial cell migration (GO:1904141) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of microglial cell migration (GO:1904140) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial outer membrane permeabilization (GO:0097345) 9 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' NAD biosynthetic process (GO:0034627) 7 0 .00 - < 0.01 1.00E00 1.00E00 ripoptosome assembly (GO:0097343) 2 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid elongation, polyunsaturated fatty acid (GO:0034626) 7 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid elongation, monounsaturated fatty acid (GO:0034625) 7 0 .00 - < 0.01 1.00E00 1.00E00 RNA splicing (GO:0008380) 380 0 .11 - < 0.01 1.00E00 1.00E00 zymogen inhibition (GO:0097341) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to unfolded protein (GO:0034620) 76 0 .02 - < 0.01 1.00E00 1.00E00 nuclear fragmentation involved in apoptotic nuclear change (GO:0030264) 1 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic chromosome condensation (GO:0030263) 6 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic nuclear changes (GO:0030262) 22 0 .01 - < 0.01 1.00E00 1.00E00 chromosome condensation (GO:0030261) 42 0 .01 - < 0.01 1.00E00 1.00E00 regulation of microglial cell migration (GO:1904139) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to laminar fluid shear stress (GO:0034616) 24 0 .01 - < 0.01 1.00E00 1.00E00 response to antipsychotic drug (GO:0097332) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to reactive oxygen species (GO:0034614) 125 0 .04 - < 0.01 1.00E00 1.00E00 response to chemical (GO:0042221) 3717 3 1.08 + 2.77 7.65E-02 1.00E00 response to tumor necrosis factor (GO:0034612) 173 0 .05 - < 0.01 1.00E00 1.00E00 response to cocaine (GO:0042220) 57 0 .02 - < 0.01 1.00E00 1.00E00 lipid glycosylation (GO:0030259) 12 0 .00 - < 0.01 1.00E00 1.00E00 lipid modification (GO:0030258) 167 0 .05 - < 0.01 1.00E00 1.00E00 growth hormone secretion (GO:0030252) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of otic vesicle morphogenesis (GO:1904120) 1 0 .00 - < 0.01 1.00E00 1.00E00 amino acid import across plasma membrane (GO:0089718) 38 0 .01 - < 0.01 1.00E00 1.00E00 modified amino acid catabolic process (GO:0042219) 32 0 .01 - < 0.01 1.00E00 1.00E00 axon ensheathment (GO:0008366) 133 0 .04 - < 0.01 1.00E00 1.00E00 response to antineoplastic agent (GO:0097327) 1 0 .00 - < 0.01 1.00E00 1.00E00 melanocyte adhesion (GO:0097326) 1 0 .00 - < 0.01 1.00E00 1.00E00 melanocyte proliferation (GO:0097325) 5 0 .00 - < 0.01 1.00E00 1.00E00 melanocyte migration (GO:0097324) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell adhesion (GO:0097323) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to heat (GO:0034605) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cell size (GO:0008361) 179 0 .05 - < 0.01 1.00E00 1.00E00 terpene metabolic process (GO:0042214) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell shape (GO:0008360) 139 0 .04 - < 0.01 1.00E00 1.00E00 plasma membrane tubulation (GO:0097320) 14 0 .00 - < 0.01 1.00E00 1.00E00 autophagy of peroxisome (GO:0030242) 16 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle myosin thick filament assembly (GO:0030241) 3 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle thin filament assembly (GO:0030240) 6 0 .00 - < 0.01 1.00E00 1.00E00 epithelial structure maintenance (GO:0010669) 36 0 .01 - < 0.01 1.00E00 1.00E00 ectodermal cell differentiation (GO:0010668) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of otic vesicle morphogenesis (GO:1904118) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle cell apoptotic process (GO:0010667) 25 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to vasopressin (GO:1904117) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle cell apoptotic process (GO:0010666) 15 0 .00 - < 0.01 1.00E00 1.00E00 response to vasopressin (GO:1904116) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle cell apoptotic process (GO:0010665) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of striated muscle cell apoptotic process (GO:0010664) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of striated muscle cell apoptotic process (GO:0010663) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of striated muscle cell apoptotic process (GO:0010662) 43 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of muscle cell apoptotic process (GO:0010661) 30 0 .01 - < 0.01 1.00E00 1.00E00 maternal determination of anterior/posterior axis, embryo (GO:0008358) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle cell apoptotic process (GO:0010660) 76 0 .02 - < 0.01 1.00E00 1.00E00 L-histidine transmembrane transport (GO:0089709) 6 0 .00 - < 0.01 1.00E00 1.00E00 asymmetric cell division (GO:0008356) 16 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine transmembrane export from vacuole (GO:0089708) 1 0 .00 - < 0.01 1.00E00 1.00E00 olfactory learning (GO:0008355) 2 0 .00 - < 0.01 1.00E00 1.00E00 germ cell migration (GO:0008354) 9 0 .00 - < 0.01 1.00E00 1.00E00 apoptosome assembly (GO:0097314) 1 0 .00 - < 0.01 1.00E00 1.00E00 myofibril assembly (GO:0030239) 68 0 .02 - < 0.01 1.00E00 1.00E00 male sex determination (GO:0030238) 14 0 .00 - < 0.01 1.00E00 1.00E00 female sex determination (GO:0030237) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle cell apoptotic process (GO:0010659) 12 0 .00 - < 0.01 1.00E00 1.00E00 striated muscle cell apoptotic process (GO:0010658) 13 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to ciliary inversin compartment (GO:1904108) 1 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell apoptotic process (GO:0010657) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of muscle cell apoptotic process (GO:0010656) 45 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to microvillus (GO:1904106) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of convergent extension involved in gastrulation (GO:1904105) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of convergent extension involved in gastrulation (GO:1904103) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication by chemical coupling (GO:0010652) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antimicrobial humoral response (GO:0008348) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication by electrical coupling (GO:0010650) 3 0 .00 - < 0.01 1.00E00 1.00E00 glial cell migration (GO:0008347) 49 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to alcohol (GO:0097306) 102 0 .03 - < 0.01 1.00E00 1.00E00 response to alcohol (GO:0097305) 275 0 .08 - < 0.01 1.00E00 1.00E00 adult locomotory behavior (GO:0008344) 84 0 .02 - < 0.01 1.00E00 1.00E00 adult feeding behavior (GO:0008343) 10 0 .00 - < 0.01 1.00E00 1.00E00 determination of adult lifespan (GO:0008340) 37 0 .01 - < 0.01 1.00E00 1.00E00 programmed necrotic cell death (GO:0097300) 27 0 .01 - < 0.01 1.00E00 1.00E00 protein-RNA complex assembly (GO:0022618) 196 0 .06 - < 0.01 1.00E00 1.00E00 extracellular matrix disassembly (GO:0022617) 47 0 .01 - < 0.01 1.00E00 1.00E00 macrophage differentiation (GO:0030225) 50 0 .01 - < 0.01 1.00E00 1.00E00 DNA strand elongation (GO:0022616) 20 0 .01 - < 0.01 1.00E00 1.00E00 monocyte differentiation (GO:0030224) 18 0 .01 - < 0.01 1.00E00 1.00E00 protein to membrane docking (GO:0022615) 5 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil differentiation (GO:0030223) 8 0 .00 - < 0.01 1.00E00 1.00E00 membrane to membrane docking (GO:0022614) 6 0 .00 - < 0.01 1.00E00 1.00E00 eosinophil differentiation (GO:0030222) 5 0 .00 - < 0.01 1.00E00 1.00E00 ribonucleoprotein complex biogenesis (GO:0022613) 452 0 .13 - < 0.01 1.00E00 1.00E00 gland morphogenesis (GO:0022612) 105 0 .03 - < 0.01 1.00E00 1.00E00 basophil differentiation (GO:0030221) 2 0 .00 - < 0.01 1.00E00 1.00E00 platelet formation (GO:0030220) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cell communication by electrical coupling (GO:0010649) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to environmental stimulus (GO:0104004) 328 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell communication (GO:0010648) 1452 0 .42 - < 0.01 1.00E00 1.00E00 positive regulation of cell communication (GO:0010647) 1770 1 .52 + 1.94 4.17E-01 1.00E00 regulation of cell communication (GO:0010646) 3510 1 1.02 - .98 1.00E00 1.00E00 regulation of cell communication by chemical coupling (GO:0010645) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell communication by electrical coupling (GO:0010644) 19 0 .01 - < 0.01 1.00E00 1.00E00 cell communication by chemical coupling (GO:0010643) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of platelet-derived growth factor receptor signaling pathway (GO:0010641) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) 25 0 .01 - < 0.01 1.00E00 1.00E00 histone mRNA metabolic process (GO:0008334) 20 0 .01 - < 0.01 1.00E00 1.00E00 endosome to lysosome transport (GO:0008333) 66 0 .02 - < 0.01 1.00E00 1.00E00 megakaryocyte differentiation (GO:0030219) 30 0 .01 - < 0.01 1.00E00 1.00E00 erythrocyte differentiation (GO:0030218) 105 0 .03 - < 0.01 1.00E00 1.00E00 T cell differentiation (GO:0030217) 188 0 .05 - < 0.01 1.00E00 1.00E00 keratinocyte differentiation (GO:0030216) 143 0 .04 - < 0.01 1.00E00 1.00E00 cellular component assembly (GO:0022607) 2501 0 .73 - < 0.01 1.00E00 1.00E00 hyaluronan catabolic process (GO:0030214) 16 0 .00 - < 0.01 1.00E00 1.00E00 mammalian oogenesis stage (GO:0022605) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell morphogenesis (GO:0022604) 247 0 .07 - < 0.01 1.00E00 1.00E00 hyaluronan biosynthetic process (GO:0030213) 6 0 .00 - < 0.01 1.00E00 1.00E00 hyaluronan metabolic process (GO:0030212) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of anatomical structure morphogenesis (GO:0022603) 836 0 .24 - < 0.01 1.00E00 1.00E00 ovulation cycle process (GO:0022602) 50 0 .01 - < 0.01 1.00E00 1.00E00 heparin proteoglycan catabolic process (GO:0030211) 1 0 .00 - < 0.01 1.00E00 1.00E00 heparin proteoglycan biosynthetic process (GO:0030210) 11 0 .00 - < 0.01 1.00E00 1.00E00 digestive system process (GO:0022600) 81 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of organelle organization (GO:0010639) 333 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of organelle organization (GO:0010638) 499 0 .15 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial fusion (GO:0010637) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial fusion (GO:0010636) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial fusion (GO:0010635) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell migration (GO:0010634) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell migration (GO:0010633) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell migration (GO:0010632) 65 0 .02 - < 0.01 1.00E00 1.00E00 epithelial cell migration (GO:0010631) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of extent of cell growth (GO:0061387) 99 0 .03 - < 0.01 1.00E00 1.00E00 regulation of transcription, start site selection (GO:0010630) 1 0 .00 - < 0.01 1.00E00 1.00E00 closure of optic fissure (GO:0061386) 2 0 .00 - < 0.01 1.00E00 1.00E00 heart trabecula morphogenesis (GO:0061384) 33 0 .01 - < 0.01 1.00E00 1.00E00 trabecula morphogenesis (GO:0061383) 46 0 .01 - < 0.01 1.00E00 1.00E00 cell migration in diencephalon (GO:0061381) 1 0 .00 - < 0.01 1.00E00 1.00E00 dermatan sulfate proteoglycan catabolic process (GO:0030209) 4 0 .00 - < 0.01 1.00E00 1.00E00 dermatan sulfate biosynthetic process (GO:0030208) 5 0 .00 - < 0.01 1.00E00 1.00E00 chondroitin sulfate proteoglycan catabolic process (GO:0030207) 4 0 .00 - < 0.01 1.00E00 1.00E00 chondroitin sulfate biosynthetic process (GO:0030206) 20 0 .01 - < 0.01 1.00E00 1.00E00 dermatan sulfate metabolic process (GO:0030205) 5 0 .00 - < 0.01 1.00E00 1.00E00 chondroitin sulfate metabolic process (GO:0030204) 23 0 .01 - < 0.01 1.00E00 1.00E00 glycosaminoglycan metabolic process (GO:0030203) 78 0 .02 - < 0.01 1.00E00 1.00E00 heparin proteoglycan metabolic process (GO:0030202) 17 0 .00 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan metabolic process (GO:0030201) 41 0 .01 - < 0.01 1.00E00 1.00E00 heparan sulfate proteoglycan catabolic process (GO:0030200) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gene expression (GO:0010629) 1037 0 .30 - < 0.01 1.00E00 1.00E00 positive regulation of gene expression (GO:0010628) 1186 0 .35 - < 0.01 1.00E00 1.00E00 negative regulation of Schwann cell proliferation (GO:0010626) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Schwann cell proliferation (GO:0010625) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Schwann cell proliferation (GO:0010624) 9 0 .00 - < 0.01 1.00E00 1.00E00 programmed cell death involved in cell development (GO:0010623) 22 0 .01 - < 0.01 1.00E00 1.00E00 inferior colliculus development (GO:0061379) 2 0 .00 - < 0.01 1.00E00 1.00E00 corpora quadrigemina development (GO:0061378) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription by transcription factor localization (GO:0010621) 3 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland lobule development (GO:0061377) 20 0 .01 - < 0.01 1.00E00 1.00E00 G2/MI transition of meiotic cell cycle (GO:0008315) 2 0 .00 - < 0.01 1.00E00 1.00E00 mammillothalamic axonal tract development (GO:0061374) 1 0 .00 - < 0.01 1.00E00 1.00E00 mammillary axonal complex development (GO:0061373) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of heart left/right asymmetry (GO:0061371) 69 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle adaptation (GO:0010616) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle adaptation (GO:0010615) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cardiac muscle hypertrophy (GO:0010614) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cardiac muscle hypertrophy (GO:0010613) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle adaptation (GO:0010612) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of testicular blood vessel morphogenesis (GO:0061369) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral response to formalin induced pain (GO:0061368) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardiac muscle hypertrophy (GO:0010611) 59 0 .02 - < 0.01 1.00E00 1.00E00 tarsal gland development (GO:1903699) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral response to acetic acid induced pain (GO:0061367) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA stability involved in response to stress (GO:0010610) 1 0 .00 - < 0.01 1.00E00 1.00E00 behavioral response to chemical pain (GO:0061366) 3 0 .00 - < 0.01 1.00E00 1.00E00 associative learning (GO:0008306) 91 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of microvillus assembly (GO:1903697) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of triglyceride lipase activity (GO:0061365) 8 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process involved in luteolysis (GO:0061364) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of wound healing, spreading of epidermal cells (GO:1903691) 5 0 .00 - < 0.01 1.00E00 1.00E00 isoprenoid catabolic process (GO:0008300) 10 0 .00 - < 0.01 1.00E00 1.00E00 optic chiasma development (GO:0061360) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of wound healing, spreading of epidermal cells (GO:1903690) 5 0 .00 - < 0.01 1.00E00 1.00E00 mRNA localization resulting in post-transcriptional regulation of gene expression (GO:0010609) 3 0 .00 - < 0.01 1.00E00 1.00E00 post-transcriptional regulation of gene expression (GO:0010608) 506 0 .15 - < 0.01 1.00E00 1.00E00 negative regulation of cytoplasmic mRNA processing body assembly (GO:0010607) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytoplasmic mRNA processing body assembly (GO:0010606) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of macromolecule metabolic process (GO:0010605) 2495 0 .73 - < 0.01 1.00E00 1.00E00 positive regulation of macromolecule metabolic process (GO:0010604) 3154 0 .92 - < 0.01 6.00E-01 1.00E00 regulation of cytoplasmic mRNA processing body assembly (GO:0010603) 8 0 .00 - < 0.01 1.00E00 1.00E00 axonal transport of mitochondrion (GO:0019896) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of wound healing, spreading of epidermal cells (GO:1903689) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt protein secretion (GO:0061358) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt protein secretion (GO:0061357) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Wnt protein secretion (GO:0061356) 5 0 .00 - < 0.01 1.00E00 1.00E00 Wnt protein secretion (GO:0061355) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural precursor cell proliferation (GO:0061351) 108 0 .03 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous peptide antigen via MHC class II (GO:0019886) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cap-independent translational initiation (GO:1903679) 3 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) 21 0 .01 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of exogenous antigen (GO:0019884) 50 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cap-independent translational initiation (GO:1903677) 3 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation of endogenous antigen (GO:0019883) 30 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cap-dependent translational initiation (GO:1903676) 3 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation (GO:0019882) 103 0 .03 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion involved in heart morphogenesis (GO:0061344) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell adhesion involved in heart morphogenesis (GO:0061343) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cap-dependent translational initiation (GO:1903674) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitotic cleavage furrow formation (GO:1903673) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sprouting angiogenesis (GO:1903672) 24 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of sprouting angiogenesis (GO:1903671) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sprouting angiogenesis (GO:1903670) 42 0 .01 - < 0.01 1.00E00 1.00E00 lysine biosynthetic process via aminoadipic acid (GO:0019878) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment or maintenance of monopolar cell polarity (GO:0061339) 25 0 .01 - < 0.01 1.00E00 1.00E00 behavioral response to nicotine (GO:0035095) 10 0 .00 - < 0.01 1.00E00 1.00E00 response to nicotine (GO:0035094) 54 0 .02 - < 0.01 1.00E00 1.00E00 cardiac conduction (GO:0061337) 68 0 .02 - < 0.01 1.00E00 1.00E00 sperm DNA condensation (GO:0035092) 17 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of apical/basal cell polarity (GO:0035090) 7 0 .00 - < 0.01 1.00E00 1.00E00 renal tubule morphogenesis (GO:0061333) 73 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of complement-dependent cytotoxicity (GO:1903661) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of complement-dependent cytotoxicity (GO:1903660) 3 0 .00 - < 0.01 1.00E00 1.00E00 establishment of apical/basal cell polarity (GO:0035089) 22 0 .01 - < 0.01 1.00E00 1.00E00 establishment or maintenance of apical/basal cell polarity (GO:0035088) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of complement-dependent cytotoxicity (GO:1903659) 8 0 .00 - < 0.01 1.00E00 1.00E00 renal tubule development (GO:0061326) 91 0 .03 - < 0.01 1.00E00 1.00E00 axoneme assembly (GO:0035082) 104 0 .03 - < 0.01 1.00E00 1.00E00 cell proliferation involved in outflow tract morphogenesis (GO:0061325) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation involved in heart morphogenesis (GO:0061323) 2 0 .00 - < 0.01 1.00E00 1.00E00 uracil metabolic process (GO:0019860) 3 0 .00 - < 0.01 1.00E00 1.00E00 thymine metabolic process (GO:0019859) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytosine metabolic process (GO:0019858) 2 0 .00 - < 0.01 1.00E00 1.00E00 renal filtration cell differentiation (GO:0061318) 23 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase biosynthetic process (GO:0019856) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-ascorbic acid metabolic process (GO:0019852) 11 0 .00 - < 0.01 1.00E00 1.00E00 Notch signaling involved in heart development (GO:0061314) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chaperone-mediated protein folding (GO:1903645) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chaperone-mediated protein folding (GO:1903644) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell surface receptor signaling pathway involved in heart development (GO:0061311) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of gastrin-induced gastric acid secretion (GO:1903640) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac neural crest cell development involved in outflow tract morphogenesis (GO:0061309) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gastrin-induced gastric acid secretion (GO:1903639) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac neural crest cell development involved in heart development (GO:0061308) 12 0 .00 - < 0.01 1.00E00 1.00E00 nuclear speck organization (GO:0035063) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac neural crest cell differentiation involved in heart development (GO:0061307) 12 0 .00 - < 0.01 1.00E00 1.00E00 retinal blood vessel morphogenesis (GO:0061304) 6 0 .00 - < 0.01 1.00E00 1.00E00 cornea development in camera-type eye (GO:0061303) 13 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle cell-matrix adhesion (GO:0061302) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum vasculature morphogenesis (GO:0061301) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellum vasculature development (GO:0061300) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic heart tube anterior/posterior pattern specification (GO:0035054) 3 0 .00 - < 0.01 1.00E00 1.00E00 cytolysis (GO:0019835) 10 0 .00 - < 0.01 1.00E00 1.00E00 cardiocyte differentiation (GO:0035051) 120 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of DNA catabolic process (GO:1903626) 6 0 .00 - < 0.01 1.00E00 1.00E00 embryonic heart tube development (GO:0035050) 84 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of DNA catabolic process (GO:1903625) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of DNA catabolic process (GO:1903624) 13 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to photoreceptor connecting cilium (GO:1903621) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transdifferentiation (GO:1903620) 1 0 .00 - < 0.01 1.00E00 1.00E00 stem cell population maintenance (GO:0019827) 121 0 .04 - < 0.01 1.00E00 1.00E00 regulation of transdifferentiation (GO:1903618) 1 0 .00 - < 0.01 1.00E00 1.00E00 sperm DNA decondensation (GO:0035041) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-dependent ATPase activity (GO:1903612) 1 0 .00 - < 0.01 1.00E00 1.00E00 male pronucleus assembly (GO:0035039) 2 0 .00 - < 0.01 1.00E00 1.00E00 female pronucleus assembly (GO:0035038) 1 0 .00 - < 0.01 1.00E00 1.00E00 sperm entry (GO:0035037) 1 0 .00 - < 0.01 1.00E00 1.00E00 sperm-egg recognition (GO:0035036) 50 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of inward rectifier potassium channel activity (GO:1903609) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cytoplasmic stress granule (GO:1903608) 8 0 .00 - < 0.01 1.00E00 1.00E00 cytochrome c metabolic process (GO:1903606) 1 0 .00 - < 0.01 1.00E00 1.00E00 cytochrome metabolic process (GO:1903604) 6 0 .00 - < 0.01 1.00E00 1.00E00 signal release (GO:0023061) 190 0 .06 - < 0.01 1.00E00 1.00E00 leading edge cell differentiation (GO:0035026) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Rho protein signal transduction (GO:0035025) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Rho protein signal transduction (GO:0035024) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of Rho protein signal transduction (GO:0035023) 86 0 .03 - < 0.01 1.00E00 1.00E00 quinolinate biosynthetic process (GO:0019805) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Rac protein signal transduction (GO:0035022) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Rac protein signal transduction (GO:0035021) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Rac protein signal transduction (GO:0035020) 28 0 .01 - < 0.01 1.00E00 1.00E00 adaptation of signaling pathway (GO:0023058) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of signaling (GO:0023057) 1452 0 .42 - < 0.01 1.00E00 1.00E00 positive regulation of signaling (GO:0023056) 1772 1 .52 + 1.94 4.17E-01 1.00E00 neural plate regionalization (GO:0060897) 5 0 .00 - < 0.01 1.00E00 1.00E00 neural plate pattern specification (GO:0060896) 7 0 .00 - < 0.01 1.00E00 1.00E00 signaling (GO:0023052) 5226 0 1.52 - < 0.01 3.48E-01 1.00E00 regulation of signaling (GO:0023051) 3502 1 1.02 - .98 1.00E00 1.00E00 somatic stem cell population maintenance (GO:0035019) 58 0 .02 - < 0.01 1.00E00 1.00E00 limb epidermis development (GO:0060887) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuronal signal transduction (GO:0023041) 7 0 .00 - < 0.01 1.00E00 1.00E00 semicircular canal fusion (GO:0060879) 1 0 .00 - < 0.01 1.00E00 1.00E00 CD40 signaling pathway (GO:0023035) 10 0 .00 - < 0.01 1.00E00 1.00E00 semicircular canal formation (GO:0060876) 2 0 .00 - < 0.01 1.00E00 1.00E00 lateral semicircular canal development (GO:0060875) 1 0 .00 - < 0.01 1.00E00 1.00E00 anterior semicircular canal development (GO:0060873) 1 0 .00 - < 0.01 1.00E00 1.00E00 semicircular canal development (GO:0060872) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of centriole replication (GO:0046599) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of viral entry into host cell (GO:0046598) 15 0 .00 - < 0.01 1.00E00 1.00E00 host-mediated suppression of symbiont invasion (GO:0046597) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of viral entry into host cell (GO:0046596) 21 0 .01 - < 0.01 1.00E00 1.00E00 termination of signal transduction (GO:0023021) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium-dependent cell-cell adhesion (GO:0046588) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium-dependent cell-cell adhesion (GO:0046587) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium-dependent cell-cell adhesion (GO:0046586) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Ras protein signal transduction (GO:0046580) 24 0 .01 - < 0.01 1.00E00 1.00E00 signal transduction involved in regulation of gene expression (GO:0023019) 28 0 .01 - < 0.01 1.00E00 1.00E00 establishment of glial blood-brain barrier (GO:0060857) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of blood-brain barrier (GO:0060856) 12 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in lymph vessel morphogenesis (GO:0060854) 1 0 .00 - < 0.01 1.00E00 1.00E00 Notch signaling pathway involved in arterial endothelial cell fate commitment (GO:0060853) 1 0 .00 - < 0.01 1.00E00 1.00E00 chondrocyte development involved in endochondral bone morphogenesis (GO:0003433) 8 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte development (GO:0003431) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Ras protein signal transduction (GO:0046579) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of Ras protein signal transduction (GO:0046578) 49 0 .01 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte growth (GO:0003430) 3 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell fate specification (GO:0060847) 4 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell fate commitment (GO:0060846) 3 0 .00 - < 0.01 1.00E00 1.00E00 arterial endothelial cell fate commitment (GO:0060844) 2 0 .00 - < 0.01 1.00E00 1.00E00 venous endothelial cell differentiation (GO:0060843) 1 0 .00 - < 0.01 1.00E00 1.00E00 arterial endothelial cell differentiation (GO:0060842) 6 0 .00 - < 0.01 1.00E00 1.00E00 venous blood vessel development (GO:0060841) 16 0 .00 - < 0.01 1.00E00 1.00E00 artery development (GO:0060840) 103 0 .03 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte morphogenesis (GO:0003429) 1 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage morphogenesis (GO:0003422) 2 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage axis specification (GO:0003421) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to oxidative stress (GO:0034599) 222 0 .06 - < 0.01 1.00E00 1.00E00 endothelial cell fate commitment (GO:0060839) 8 0 .00 - < 0.01 1.00E00 1.00E00 lymphatic endothelial cell fate commitment (GO:0060838) 3 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell differentiation (GO:0060837) 11 0 .00 - < 0.01 1.00E00 1.00E00 lymphatic endothelial cell differentiation (GO:0060836) 8 0 .00 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in dorsal/ventral neural tube patterning (GO:0060831) 4 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte proliferation (GO:0003419) 3 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage chondrocyte differentiation (GO:0003418) 9 0 .00 - < 0.01 1.00E00 1.00E00 growth plate cartilage development (GO:0003417) 19 0 .01 - < 0.01 1.00E00 1.00E00 endochondral bone growth (GO:0003416) 28 0 .01 - < 0.01 1.00E00 1.00E00 chondrocyte hypertrophy (GO:0003415) 5 0 .00 - < 0.01 1.00E00 1.00E00 chondrocyte morphogenesis involved in endochondral bone morphogenesis (GO:0003414) 1 0 .00 - < 0.01 1.00E00 1.00E00 chondrocyte differentiation involved in endochondral bone morphogenesis (GO:0003413) 14 0 .00 - < 0.01 1.00E00 1.00E00 establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis (GO:0003412) 1 0 .00 - < 0.01 1.00E00 1.00E00 photoreceptor cell fate commitment (GO:0046552) 1 0 .00 - < 0.01 1.00E00 1.00E00 hydroxyproline transport (GO:0034589) 1 0 .00 - < 0.01 1.00E00 1.00E00 halogenated hydrocarbon metabolic process (GO:0042197) 1 0 .00 - < 0.01 1.00E00 1.00E00 piRNA processing (GO:0034587) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of canonical Wnt signaling pathway (GO:0060828) 260 0 .08 - < 0.01 1.00E00 1.00E00 optic cup structural organization (GO:0003409) 1 0 .00 - < 0.01 1.00E00 1.00E00 optic cup formation involved in camera-type eye development (GO:0003408) 2 0 .00 - < 0.01 1.00E00 1.00E00 neural retina development (GO:0003407) 83 0 .02 - < 0.01 1.00E00 1.00E00 retinal pigment epithelium development (GO:0003406) 10 0 .00 - < 0.01 1.00E00 1.00E00 optic vesicle morphogenesis (GO:0003404) 2 0 .00 - < 0.01 1.00E00 1.00E00 retinal cone cell development (GO:0046549) 11 0 .00 - < 0.01 1.00E00 1.00E00 axis elongation (GO:0003401) 25 0 .01 - < 0.01 1.00E00 1.00E00 retinal rod cell development (GO:0046548) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of COPII vesicle coating (GO:0003400) 5 0 .00 - < 0.01 1.00E00 1.00E00 development of primary male sexual characteristics (GO:0046546) 149 0 .04 - < 0.01 1.00E00 1.00E00 development of primary female sexual characteristics (GO:0046545) 102 1 .03 + 33.63 2.94E-02 1.00E00 positive regulation of autophagic cell death (GO:1904094) 1 0 .00 - < 0.01 1.00E00 1.00E00 development of secondary male sexual characteristics (GO:0046544) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of autophagic cell death (GO:1904093) 3 0 .00 - < 0.01 1.00E00 1.00E00 development of secondary female sexual characteristics (GO:0046543) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of autophagic cell death (GO:1904092) 4 0 .00 - < 0.01 1.00E00 1.00E00 saliva secretion (GO:0046541) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nucleus size (GO:0097298) 1 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' XMP biosynthetic process (GO:0097294) 7 0 .00 - < 0.01 1.00E00 1.00E00 XMP biosynthetic process (GO:0097293) 7 0 .00 - < 0.01 1.00E00 1.00E00 XMP metabolic process (GO:0097292) 7 0 .00 - < 0.01 1.00E00 1.00E00 renal phosphate ion absorption (GO:0097291) 2 0 .00 - < 0.01 1.00E00 1.00E00 ketone catabolic process (GO:0042182) 17 0 .00 - < 0.01 1.00E00 1.00E00 random inactivation of X chromosome (GO:0060816) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of photoreceptor cell differentiation (GO:0046533) 6 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine nucleobase transmembrane transport (GO:1904082) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of photoreceptor cell differentiation (GO:0046532) 6 0 .00 - < 0.01 1.00E00 1.00E00 photoreceptor cell differentiation (GO:0046530) 69 0 .02 - < 0.01 1.00E00 1.00E00 xenobiotic catabolic process (GO:0042178) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein catabolic process (GO:0042177) 114 0 .03 - < 0.01 1.00E00 1.00E00 hepatocyte apoptotic process (GO:0097284) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein catabolic process (GO:0042176) 371 0 .11 - < 0.01 1.00E00 1.00E00 keratinocyte apoptotic process (GO:0097283) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesodermal to mesenchymal transition involved in gastrulation (GO:0060809) 3 0 .00 - < 0.01 1.00E00 1.00E00 immune complex formation (GO:0097281) 1 0 .00 - < 0.01 1.00E00 1.00E00 histamine secretion mediated by immunoglobulin (GO:0097280) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell differentiation involved in embryonic placenta development (GO:0060806) 1 0 .00 - < 0.01 1.00E00 1.00E00 epiblast cell-extraembryonic ectoderm cell signaling (GO:0060802) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell differentiation involved in embryonic placenta development (GO:0060800) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of trophectodermal cell proliferation (GO:1904075) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of trophectodermal cell proliferation (GO:1904073) 1 0 .00 - < 0.01 1.00E00 1.00E00 histamine secretion mediated by IgE immunoglobulin (GO:0097279) 1 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic active zone assembly (GO:1904071) 3 0 .00 - < 0.01 1.00E00 1.00E00 sphingoid catabolic process (GO:0046521) 1 0 .00 - < 0.01 1.00E00 1.00E00 complement-dependent cytotoxicity (GO:0097278) 3 0 .00 - < 0.01 1.00E00 1.00E00 sphingoid biosynthetic process (GO:0046520) 15 0 .00 - < 0.01 1.00E00 1.00E00 heme metabolic process (GO:0042168) 41 0 .01 - < 0.01 1.00E00 1.00E00 heme catabolic process (GO:0042167) 11 0 .00 - < 0.01 1.00E00 1.00E00 intracellular ammonium homeostasis (GO:0097275) 1 0 .00 - < 0.01 1.00E00 1.00E00 ammonium homeostasis (GO:0097272) 7 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex II assembly (GO:0034553) 4 0 .00 - < 0.01 1.00E00 1.00E00 respiratory chain complex II assembly (GO:0034552) 4 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein oxidation (GO:0042161) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial respiratory chain complex III assembly (GO:0034551) 13 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein modification (GO:0042160) 1 0 .00 - < 0.01 1.00E00 1.00E00 collagen fibril organization (GO:0030199) 63 0 .02 - < 0.01 1.00E00 1.00E00 extracellular matrix organization (GO:0030198) 281 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of blood coagulation (GO:0030195) 46 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of blood coagulation (GO:0030194) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of blood coagulation (GO:0030193) 69 0 .02 - < 0.01 1.00E00 1.00E00 sphingoid metabolic process (GO:0046519) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cation transmembrane transport (GO:1904064) 137 0 .04 - < 0.01 1.00E00 1.00E00 ceramide catabolic process (GO:0046514) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cation transmembrane transport (GO:1904063) 75 0 .02 - < 0.01 1.00E00 1.00E00 ceramide biosynthetic process (GO:0046513) 58 0 .02 - < 0.01 1.00E00 1.00E00 regulation of monoatomic cation transmembrane transport (GO:1904062) 287 0 .08 - < 0.01 1.00E00 1.00E00 sphingosine biosynthetic process (GO:0046512) 15 0 .00 - < 0.01 1.00E00 1.00E00 sphinganine biosynthetic process (GO:0046511) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein catabolic process (GO:0042159) 15 0 .00 - < 0.01 1.00E00 1.00E00 omega-hydroxylase P450 pathway (GO:0097267) 11 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein biosynthetic process (GO:0042158) 44 0 .01 - < 0.01 1.00E00 1.00E00 lipoprotein metabolic process (GO:0042157) 77 0 .02 - < 0.01 1.00E00 1.00E00 self proteolysis (GO:0097264) 11 0 .00 - < 0.01 1.00E00 1.00E00 melatonin biosynthetic process (GO:0030187) 2 0 .00 - < 0.01 1.00E00 1.00E00 melatonin metabolic process (GO:0030186) 2 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide transport (GO:0030185) 4 0 .00 - < 0.01 1.00E00 1.00E00 B cell differentiation (GO:0030183) 115 0 .03 - < 0.01 1.00E00 1.00E00 neuron differentiation (GO:0030182) 1127 0 .33 - < 0.01 1.00E00 1.00E00 regulation of locomotor rhythm (GO:1904059) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sensory perception of pain (GO:1904058) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sensory perception of pain (GO:1904057) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cholangiocyte proliferation (GO:1904056) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cholangiocyte proliferation (GO:1904055) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cholangiocyte proliferation (GO:1904054) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycerol ether biosynthetic process (GO:0046504) 12 0 .00 - < 0.01 1.00E00 1.00E00 glycerolipid catabolic process (GO:0046503) 57 0 .02 - < 0.01 1.00E00 1.00E00 isoprenoid biosynthetic process (GO:0008299) 28 0 .01 - < 0.01 1.00E00 1.00E00 uroporphyrinogen III metabolic process (GO:0046502) 2 0 .00 - < 0.01 1.00E00 1.00E00 intracellular mRNA localization (GO:0008298) 11 0 .00 - < 0.01 1.00E00 1.00E00 protoporphyrinogen IX metabolic process (GO:0046501) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of spontaneous neurotransmitter secretion (GO:1904050) 1 0 .00 - < 0.01 1.00E00 1.00E00 S-adenosylmethionine metabolic process (GO:0046500) 11 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glucose starvation (GO:0042149) 49 0 .01 - < 0.01 1.00E00 1.00E00 spermidine biosynthetic process (GO:0008295) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand invasion (GO:0042148) 5 0 .00 - < 0.01 1.00E00 1.00E00 retrograde transport, endosome to Golgi (GO:0042147) 99 0 .03 - < 0.01 1.00E00 1.00E00 renal tubular secretion (GO:0097254) 10 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine biosynthetic process (GO:0008292) 3 0 .00 - < 0.01 1.00E00 1.00E00 acetylcholine metabolic process (GO:0008291) 6 0 .00 - < 0.01 1.00E00 1.00E00 oligodendrocyte apoptotic process (GO:0097252) 2 0 .00 - < 0.01 1.00E00 1.00E00 vacuole fusion, non-autophagic (GO:0042144) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial respirasome assembly (GO:0097250) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt signaling pathway (GO:0030178) 171 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt signaling pathway (GO:0030177) 147 0 .04 - < 0.01 1.00E00 1.00E00 regulation of DNA-templated DNA replication initiation (GO:0030174) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of spontaneous neurotransmitter secretion (GO:1904049) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spontaneous neurotransmitter secretion (GO:1904048) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endothelial cell migration (GO:0010596) 54 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of vascular endothelial growth factor production (GO:1904046) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endothelial cell migration (GO:0010595) 107 0 .03 - < 0.01 1.00E00 1.00E00 cellular response to aldosterone (GO:1904045) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endothelial cell migration (GO:0010594) 170 0 .05 - < 0.01 1.00E00 1.00E00 response to aldosterone (GO:1904044) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lamellipodium assembly (GO:0010593) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lamellipodium assembly (GO:0010592) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cystathionine beta-synthase activity (GO:1904042) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lamellipodium assembly (GO:0010591) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of iron export across plasma membrane (GO:1904040) 1 0 .00 - < 0.01 1.00E00 1.00E00 insulin receptor signaling pathway (GO:0008286) 116 0 .03 - < 0.01 1.00E00 1.00E00 meiotic DNA double-strand break formation (GO:0042138) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell population proliferation (GO:0008285) 704 0 .21 - < 0.01 1.00E00 1.00E00 positive regulation of cell population proliferation (GO:0008284) 934 0 .27 - < 0.01 1.00E00 1.00E00 cell population proliferation (GO:0008283) 725 0 .21 - < 0.01 1.00E00 1.00E00 amyloid-beta clearance (GO:0097242) 26 0 .01 - < 0.01 1.00E00 1.00E00 hematopoietic stem cell migration to bone marrow (GO:0097241) 5 0 .00 - < 0.01 1.00E00 1.00E00 chromosome attachment to the nuclear envelope (GO:0097240) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell proliferation (GO:0042130) 76 0 .02 - < 0.01 1.00E00 1.00E00 platelet activation (GO:0030168) 102 0 .03 - < 0.01 1.00E00 1.00E00 proteoglycan catabolic process (GO:0030167) 16 0 .00 - < 0.01 1.00E00 1.00E00 proteoglycan biosynthetic process (GO:0030166) 78 0 .02 - < 0.01 1.00E00 1.00E00 protein catabolic process (GO:0030163) 794 0 .23 - < 0.01 1.00E00 1.00E00 regulation of proteolysis (GO:0030162) 393 0 .11 - < 0.01 1.00E00 1.00E00 negative regulation of iron export across plasma membrane (GO:1904039) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of iron export across plasma membrane (GO:1904038) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell apoptotic process (GO:1904037) 17 0 .00 - < 0.01 1.00E00 1.00E00 miRNA catabolic process (GO:0010587) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell apoptotic process (GO:1904036) 28 0 .01 - < 0.01 1.00E00 1.00E00 miRNA metabolic process (GO:0010586) 22 0 .01 - < 0.01 1.00E00 1.00E00 glutamine secretion (GO:0010585) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell apoptotic process (GO:1904035) 50 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of t-SNARE clustering (GO:1904034) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of t-SNARE clustering (GO:1904032) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cyclin-dependent protein kinase activity (GO:1904031) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of G protein-coupled receptor signaling pathway (GO:0008277) 159 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of cyclin-dependent protein kinase activity (GO:1904030) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to methylglyoxal (GO:0097238) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to toxic substance (GO:0097237) 129 0 .04 - < 0.01 1.00E00 1.00E00 regulation of T cell proliferation (GO:0042129) 184 0 .05 - < 0.01 1.00E00 1.00E00 regulation of cell population proliferation (GO:0042127) 1659 0 .48 - < 0.01 1.00E00 1.00E00 ribophagy (GO:0034517) 2 0 .00 - < 0.01 1.00E00 1.00E00 nitrate metabolic process (GO:0042126) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to vitamin B6 (GO:0034516) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial unfolded protein response (GO:0034514) 2 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic juice secretion (GO:0030157) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell adhesion (GO:0030155) 799 0 .23 - < 0.01 1.00E00 1.00E00 cell differentiation (GO:0030154) 3711 0 1.08 - < 0.01 6.00E-01 1.00E00 protein import into mitochondrial matrix (GO:0030150) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of collagen fibril organization (GO:1904028) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of collagen fibril organization (GO:1904027) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of collagen fibril organization (GO:1904026) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vascular endothelial growth factor production (GO:0010575) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of glucose catabolic process to lactate via pyruvate (GO:1904025) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular endothelial growth factor production (GO:0010574) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glucose catabolic process to lactate via pyruvate (GO:1904024) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucose catabolic process to lactate via pyruvate (GO:1904023) 3 0 .00 - < 0.01 1.00E00 1.00E00 vascular endothelial growth factor production (GO:0010573) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of platelet activation (GO:0010572) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of G protein-coupled receptor internalization (GO:1904022) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nuclear cell cycle DNA replication (GO:0010571) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G protein-coupled receptor internalization (GO:1904021) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of G protein-coupled receptor internalization (GO:1904020) 6 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil activation (GO:0042119) 31 0 .01 - < 0.01 1.00E00 1.00E00 endothelial cell activation (GO:0042118) 10 0 .00 - < 0.01 1.00E00 1.00E00 centromere complex assembly (GO:0034508) 24 0 .01 - < 0.01 1.00E00 1.00E00 monocyte activation (GO:0042117) 9 0 .00 - < 0.01 1.00E00 1.00E00 macrophage activation (GO:0042116) 62 0 .02 - < 0.01 1.00E00 1.00E00 tooth mineralization (GO:0034505) 23 0 .01 - < 0.01 1.00E00 1.00E00 mitochondrial mRNA polyadenylation (GO:0097222) 1 0 .00 - < 0.01 1.00E00 1.00E00 B cell activation (GO:0042113) 194 0 .06 - < 0.01 1.00E00 1.00E00 protein localization to nucleus (GO:0034504) 200 0 .06 - < 0.01 1.00E00 1.00E00 protein localization to chromosome (GO:0034502) 92 0 .03 - < 0.01 1.00E00 1.00E00 T cell activation (GO:0042110) 339 0 .10 - < 0.01 1.00E00 1.00E00 protein localization to kinetochore (GO:0034501) 13 0 .00 - < 0.01 1.00E00 1.00E00 sphingolipid catabolic process (GO:0030149) 42 0 .01 - < 0.01 1.00E00 1.00E00 sphingolipid biosynthetic process (GO:0030148) 106 0 .03 - < 0.01 1.00E00 1.00E00 regulation of double-strand break repair via homologous recombination (GO:0010569) 82 0 .02 - < 0.01 1.00E00 1.00E00 epithelial cell apoptotic process (GO:1904019) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of vasculature development (GO:1904018) 172 0 .05 - < 0.01 1.00E00 1.00E00 cellular response to Thyroglobulin triiodothyronine (GO:1904017) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ketone biosynthetic process (GO:0010566) 21 0 .01 - < 0.01 1.00E00 1.00E00 response to Thyroglobulin triiodothyronine (GO:1904016) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ketone metabolic process (GO:0010565) 132 0 .04 - < 0.01 1.00E00 1.00E00 cellular response to serotonin (GO:1904015) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell cycle process (GO:0010564) 734 0 .21 - < 0.01 1.00E00 1.00E00 response to serotonin (GO:1904014) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphorus metabolic process (GO:0010563) 219 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of phosphorus metabolic process (GO:0010562) 398 0 .12 - < 0.01 1.00E00 1.00E00 negative regulation of glycoprotein biosynthetic process (GO:0010561) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glycoprotein biosynthetic process (GO:0010560) 19 0 .01 - < 0.01 1.00E00 1.00E00 response to Aroclor 1254 (GO:1904010) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lysosomal membrane permeability (GO:0097214) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lysosomal membrane permeability (GO:0097213) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of activated T cell proliferation (GO:0042104) 25 0 .01 - < 0.01 1.00E00 1.00E00 lysosomal membrane organization (GO:0097212) 15 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to gonadotropin-releasing hormone (GO:0097211) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to gonadotropin-releasing hormone (GO:0097210) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell proliferation (GO:0042102) 104 0 .03 - < 0.01 1.00E00 1.00E00 B cell proliferation (GO:0042100) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of lung blood pressure (GO:0014916) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell migration (GO:0014912) 25 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell migration (GO:0014911) 40 0 .01 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell migration (GO:0014910) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of glycoprotein biosynthetic process (GO:0010559) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of macromolecule biosynthetic process (GO:0010558) 2099 0 .61 - < 0.01 1.00E00 1.00E00 tRNA threonylcarbamoyladenosine modification (GO:0002949) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macromolecule biosynthetic process (GO:0010557) 2539 0 .74 - < 0.01 1.00E00 1.00E00 regulation of macromolecule biosynthetic process (GO:0010556) 5086 0 1.48 - < 0.01 3.47E-01 1.00E00 tRNA C5-cytosine methylation (GO:0002946) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of sebum secreting cell proliferation (GO:1904003) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sebum secreting cell proliferation (GO:1904002) 2 0 .00 - < 0.01 1.00E00 1.00E00 tRNA dihydrouridine synthesis (GO:0002943) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of eating behavior (GO:1904000) 3 0 .00 - < 0.01 1.00E00 1.00E00 tRNA N2-guanine methylation (GO:0002940) 2 0 .00 - < 0.01 1.00E00 1.00E00 renal filtration (GO:0097205) 23 0 .01 - < 0.01 1.00E00 1.00E00 smooth muscle cell migration (GO:0014909) 14 0 .00 - < 0.01 1.00E00 1.00E00 myotube differentiation involved in skeletal muscle regeneration (GO:0014908) 9 0 .00 - < 0.01 1.00E00 1.00E00 myotube cell development involved in skeletal muscle regeneration (GO:0014906) 1 0 .00 - < 0.01 1.00E00 1.00E00 myoblast fusion involved in skeletal muscle regeneration (GO:0014905) 5 0 .00 - < 0.01 1.00E00 1.00E00 myotube cell development (GO:0014904) 37 0 .01 - < 0.01 1.00E00 1.00E00 myotube differentiation (GO:0014902) 78 0 .02 - < 0.01 1.00E00 1.00E00 satellite cell activation involved in skeletal muscle regeneration (GO:0014901) 3 0 .00 - < 0.01 1.00E00 1.00E00 muscle hyperplasia (GO:0014900) 2 0 .00 - < 0.01 1.00E00 1.00E00 tRNA N1-guanine methylation (GO:0002939) 3 0 .00 - < 0.01 1.00E00 1.00E00 bradykinin biosynthetic process (GO:0002936) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of platelet activation (GO:0010544) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of platelet activation (GO:0010543) 54 0 .02 - < 0.01 1.00E00 1.00E00 desmosome organization (GO:0002934) 14 0 .00 - < 0.01 1.00E00 1.00E00 retina vasculature morphogenesis in camera-type eye (GO:0061299) 10 0 .00 - < 0.01 1.00E00 1.00E00 lipid hydroxylation (GO:0002933) 7 0 .00 - < 0.01 1.00E00 1.00E00 retina vasculature development in camera-type eye (GO:0061298) 20 0 .01 - < 0.01 1.00E00 1.00E00 response to ischemia (GO:0002931) 64 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis (GO:0061296) 1 0 .00 - < 0.01 1.00E00 1.00E00 trabecular meshwork development (GO:0002930) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis (GO:0061295) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway (GO:0030111) 335 0 .10 - < 0.01 1.00E00 1.00E00 tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation (GO:0002926) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002925) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002924) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) 17 0 .00 - < 0.01 1.00E00 1.00E00 opsonization (GO:0008228) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of humoral immune response (GO:0002922) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of humoral immune response (GO:0002921) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of humoral immune response (GO:0002920) 45 0 .01 - < 0.01 1.00E00 1.00E00 vasopressin secretion (GO:0030103) 3 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell activation (GO:0030101) 65 0 .02 - < 0.01 1.00E00 1.00E00 regulation of endocytosis (GO:0030100) 302 0 .09 - < 0.01 1.00E00 1.00E00 transposable element silencing (GO:0010526) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion transport into cytosol (GO:0010524) 14 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion transport into cytosol (GO:0010523) 5 0 .00 - < 0.01 1.00E00 1.00E00 cell death (GO:0008219) 1100 0 .32 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte anergy (GO:0002913) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcium ion transport into cytosol (GO:0010522) 20 0 .01 - < 0.01 1.00E00 1.00E00 regulation of blood pressure (GO:0008217) 197 0 .06 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte anergy (GO:0002911) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of reciprocal meiotic recombination (GO:0010520) 3 0 .00 - < 0.01 1.00E00 1.00E00 spermidine metabolic process (GO:0008216) 8 0 .00 - < 0.01 1.00E00 1.00E00 spermine metabolic process (GO:0008215) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein dealkylation (GO:0008214) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein alkylation (GO:0008213) 45 0 .01 - < 0.01 1.00E00 1.00E00 mineralocorticoid metabolic process (GO:0008212) 6 0 .00 - < 0.01 1.00E00 1.00E00 glucocorticoid metabolic process (GO:0008211) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipase activity (GO:0010519) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipase activity (GO:0010518) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipase activity (GO:0010517) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mature B cell apoptotic process (GO:0002906) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mature B cell apoptotic process (GO:0002905) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of B cell apoptotic process (GO:0002904) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphatidylinositol biosynthetic process (GO:0010513) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of B cell apoptotic process (GO:0002903) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of phosphatidylinositol biosynthetic process (GO:0010512) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell apoptotic process (GO:0002902) 20 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of autophagy of mitochondrion (GO:1903599) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of phosphatidylinositol biosynthetic process (GO:0010511) 5 0 .00 - < 0.01 1.00E00 1.00E00 C21-steroid hormone metabolic process (GO:0008207) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of gap junction assembly (GO:1903598) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) 7 0 .00 - < 0.01 1.00E00 1.00E00 mature B cell apoptotic process (GO:0002901) 1 0 .00 - < 0.01 1.00E00 1.00E00 bile acid metabolic process (GO:0008206) 39 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of gap junction assembly (GO:1903597) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of gap junction assembly (GO:1903596) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of histamine secretion by mast cell (GO:1903595) 4 0 .00 - < 0.01 1.00E00 1.00E00 cholesterol metabolic process (GO:0008203) 120 0 .03 - < 0.01 1.00E00 1.00E00 regulation of histamine secretion by mast cell (GO:1903593) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of autophagy (GO:0010508) 159 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of autophagy (GO:0010507) 97 0 .03 - < 0.01 1.00E00 1.00E00 regulation of autophagy (GO:0010506) 363 0 .11 - < 0.01 1.00E00 1.00E00 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903589) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903588) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis (GO:1903587) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ATP metabolic process (GO:1903580) 37 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of ATP metabolic process (GO:1903579) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of ATP metabolic process (GO:1903578) 75 0 .02 - < 0.01 1.00E00 1.00E00 cellular response to L-arginine (GO:1903577) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment or maintenance of bipolar cell polarity (GO:0061245) 53 0 .02 - < 0.01 1.00E00 1.00E00 response to L-arginine (GO:1903576) 4 0 .00 - < 0.01 1.00E00 1.00E00 cornified envelope assembly (GO:1903575) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to endoplasmic reticulum stress (GO:1903573) 49 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to ciliary membrane (GO:1903569) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to ciliary membrane (GO:1903568) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to ciliary membrane (GO:1903567) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to cilium (GO:1903566) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to cilium (GO:1903565) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to cilium (GO:1903564) 11 0 .00 - < 0.01 1.00E00 1.00E00 pattern specification involved in mesonephros development (GO:0061227) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) 110 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556) 66 0 .02 - < 0.01 1.00E00 1.00E00 regulation of tumor necrosis factor superfamily cytokine production (GO:1903555) 175 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular exosome assembly (GO:1903553) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extracellular exosome assembly (GO:1903551) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mesonephros development (GO:0061218) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesonephros development (GO:0061217) 5 0 .00 - < 0.01 1.00E00 1.00E00 one-carbon compound transport (GO:0019755) 23 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to photoreceptor outer segment (GO:1903546) 7 0 .00 - < 0.01 1.00E00 1.00E00 carboxylic acid metabolic process (GO:0019752) 763 0 .22 - < 0.01 1.00E00 1.00E00 cellular response to butyrate (GO:1903545) 1 0 .00 - < 0.01 1.00E00 1.00E00 polyol metabolic process (GO:0019751) 97 0 .03 - < 0.01 1.00E00 1.00E00 response to butyrate (GO:1903544) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of exosomal secretion (GO:1903543) 15 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of exosomal secretion (GO:1903542) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of exosomal secretion (GO:1903541) 17 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to postsynaptic membrane (GO:1903540) 12 0 .00 - < 0.01 1.00E00 1.00E00 secondary metabolic process (GO:0019748) 49 0 .01 - < 0.01 1.00E00 1.00E00 cell proliferation involved in mesonephros development (GO:0061209) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of isoprenoid metabolic process (GO:0019747) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to postsynaptic membrane (GO:1903539) 31 0 .01 - < 0.01 1.00E00 1.00E00 regulation of meiotic cell cycle process involved in oocyte maturation (GO:1903538) 2 0 .00 - < 0.01 1.00E00 1.00E00 meiotic cell cycle process involved in oocyte maturation (GO:1903537) 5 0 .00 - < 0.01 1.00E00 1.00E00 paramesonephric duct development (GO:0061205) 4 0 .00 - < 0.01 1.00E00 1.00E00 pentacyclic triterpenoid metabolic process (GO:0019742) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein targeting (GO:1903533) 78 0 .02 - < 0.01 1.00E00 1.00E00 nitrogen utilization (GO:0019740) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secretion by cell (GO:1903532) 298 1 .09 + 11.51 8.38E-02 1.00E00 negative regulation of secretion by cell (GO:1903531) 146 0 .04 - < 0.01 1.00E00 1.00E00 regulation of secretion by cell (GO:1903530) 566 1 .17 + 6.06 1.54E-01 1.00E00 positive regulation of membrane tubulation (GO:1903527) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane tubulation (GO:1903526) 2 0 .00 - < 0.01 1.00E00 1.00E00 antifungal humoral response (GO:0019732) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane tubulation (GO:1903525) 5 0 .00 - < 0.01 1.00E00 1.00E00 antibacterial humoral response (GO:0019731) 67 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of blood circulation (GO:1903524) 39 0 .01 - < 0.01 1.00E00 1.00E00 antimicrobial humoral response (GO:0019730) 167 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of blood circulation (GO:1903523) 23 0 .01 - < 0.01 1.00E00 1.00E00 regulation of blood circulation (GO:1903522) 256 0 .07 - < 0.01 1.00E00 1.00E00 cellular homeostasis (GO:0019725) 689 0 .20 - < 0.01 1.00E00 1.00E00 positive regulation of single strand break repair (GO:1903518) 3 0 .00 - < 0.01 1.00E00 1.00E00 B cell mediated immunity (GO:0019724) 189 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of single strand break repair (GO:1903517) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of single strand break repair (GO:1903516) 4 0 .00 - < 0.01 1.00E00 1.00E00 calcium-mediated signaling (GO:0019722) 167 0 .05 - < 0.01 1.00E00 1.00E00 calcium ion transport from cytosol to endoplasmic reticulum (GO:1903515) 2 0 .00 - < 0.01 1.00E00 1.00E00 release of sequestered calcium ion into cytosol by endoplasmic reticulum (GO:1903514) 11 0 .00 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum to cytosol transport (GO:1903513) 19 0 .01 - < 0.01 1.00E00 1.00E00 Mo-molybdopterin cofactor metabolic process (GO:0019720) 6 0 .00 - < 0.01 1.00E00 1.00E00 phytanic acid metabolic process (GO:1903512) 2 0 .00 - < 0.01 1.00E00 1.00E00 liposaccharide metabolic process (GO:1903509) 108 0 .03 - < 0.01 1.00E00 1.00E00 regulation of mitotic spindle checkpoint (GO:1903504) 24 0 .01 - < 0.01 1.00E00 1.00E00 apical constriction (GO:0003383) 5 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell morphogenesis (GO:0003382) 37 0 .01 - < 0.01 1.00E00 1.00E00 cell fate commitment involved in formation of primary germ layer (GO:0060795) 28 0 .01 - < 0.01 1.00E00 1.00E00 sweat gland development (GO:0060792) 1 0 .00 - < 0.01 1.00E00 1.00E00 sphingosine-1-phosphate receptor signaling pathway (GO:0003376) 16 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to camptothecin (GO:0072757) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to glutathione (GO:0072753) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to rapamycin (GO:0072752) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to leptomycin B (GO:0072750) 1 0 .00 - < 0.01 1.00E00 1.00E00 hair follicle placode formation (GO:0060789) 5 0 .00 - < 0.01 1.00E00 1.00E00 ectodermal placode formation (GO:0060788) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of apoptosis involved in tissue homeostasis (GO:0060785) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in tissue homeostasis (GO:0060784) 1 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal smoothened signaling pathway involved in prostate gland development (GO:0060783) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation involved in prostate gland development (GO:0060782) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell-matrix adhesion involved in ameboidal cell migration (GO:0003366) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of cell polarity involved in ameboidal cell migration (GO:0003365) 3 0 .00 - < 0.01 1.00E00 1.00E00 lamellipodium assembly involved in ameboidal cell migration (GO:0003363) 1 0 .00 - < 0.01 1.00E00 1.00E00 brainstem development (GO:0003360) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to cytochalasin B (GO:0072749) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell division site (GO:0072741) 2 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to anisomycin (GO:0072740) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epithelial cell proliferation involved in prostate gland development (GO:0060770) 6 0 .00 - < 0.01 1.00E00 1.00E00 noradrenergic neuron fate commitment (GO:0003359) 1 0 .00 - < 0.01 1.00E00 1.00E00 noradrenergic neuron development (GO:0003358) 5 0 .00 - < 0.01 1.00E00 1.00E00 noradrenergic neuron differentiation (GO:0003357) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium beat frequency (GO:0003356) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cilium movement (GO:0003354) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cilium movement (GO:0003353) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cilium movement (GO:0003352) 44 0 .01 - < 0.01 1.00E00 1.00E00 S-adenosylmethioninamine metabolic process (GO:0046499) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cilium movement involved in extracellular fluid movement (GO:0003351) 48 0 .01 - < 0.01 1.00E00 1.00E00 S-adenosylhomocysteine metabolic process (GO:0046498) 2 0 .00 - < 0.01 1.00E00 1.00E00 pulmonary myocardium development (GO:0003350) 2 0 .00 - < 0.01 1.00E00 1.00E00 nicotinamide nucleotide metabolic process (GO:0046496) 128 0 .04 - < 0.01 1.00E00 1.00E00 nicotinamide riboside metabolic process (GO:0046495) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to anisomycin (GO:0072739) 3 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to diamide (GO:0072738) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to diamide (GO:0072737) 2 0 .00 - < 0.01 1.00E00 1.00E00 heme B metabolic process (GO:0046492) 8 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to tert-butyl hydroperoxide (GO:0072736) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-methylmalonyl-CoA metabolic process (GO:0046491) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to tert-butyl hydroperoxide (GO:0072735) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to staurosporine (GO:0072734) 5 0 .00 - < 0.01 1.00E00 1.00E00 isopentenyl diphosphate metabolic process (GO:0046490) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to staurosporine (GO:0072733) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to calcium ion starvation (GO:0072732) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation involved in prostate gland development (GO:0060769) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) 10 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in prostate gland development (GO:0060767) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of androgen receptor signaling pathway (GO:0060766) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of androgen receptor signaling pathway (GO:0060765) 31 0 .01 - < 0.01 1.00E00 1.00E00 cell-cell signaling involved in mammary gland development (GO:0060764) 2 0 .00 - < 0.01 1.00E00 1.00E00 mammary duct terminal end bud growth (GO:0060763) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching involved in mammary gland duct morphogenesis (GO:0060762) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to cytokine stimulus (GO:0060761) 88 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of response to cytokine stimulus (GO:0060760) 67 0 .02 - < 0.01 1.00E00 1.00E00 cardiac endothelial cell differentiation (GO:0003348) 6 0 .00 - < 0.01 1.00E00 1.00E00 proepicardium cell migration involved in pericardium morphogenesis (GO:0003345) 1 0 .00 - < 0.01 1.00E00 1.00E00 pericardium morphogenesis (GO:0003344) 8 0 .00 - < 0.01 1.00E00 1.00E00 septum transversum development (GO:0003343) 2 0 .00 - < 0.01 1.00E00 1.00E00 proepicardium development (GO:0003342) 2 0 .00 - < 0.01 1.00E00 1.00E00 cilium movement (GO:0003341) 238 0 .07 - < 0.01 1.00E00 1.00E00 phosphatidylinositol metabolic process (GO:0046488) 146 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003340) 2 0 .00 - < 0.01 1.00E00 1.00E00 glyoxylate metabolic process (GO:0046487) 8 0 .00 - < 0.01 1.00E00 1.00E00 glycerolipid metabolic process (GO:0046486) 351 0 .10 - < 0.01 1.00E00 1.00E00 ether lipid metabolic process (GO:0046485) 22 0 .01 - < 0.01 1.00E00 1.00E00 response to amitrole (GO:0072722) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to dithiothreitol (GO:0072721) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to dithiothreitol (GO:0072720) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to cytokine stimulus (GO:0060759) 179 0 .05 - < 0.01 1.00E00 1.00E00 negative regulation of mast cell chemotaxis (GO:0060755) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mast cell chemotaxis (GO:0060754) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mast cell chemotaxis (GO:0060753) 8 0 .00 - < 0.01 1.00E00 1.00E00 branch elongation involved in mammary gland duct branching (GO:0060751) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339) 7 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in mammary gland duct elongation (GO:0060750) 4 0 .00 - < 0.01 1.00E00 1.00E00 metanephros morphogenesis (GO:0003338) 26 0 .01 - < 0.01 1.00E00 1.00E00 mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) 7 0 .00 - < 0.01 1.00E00 1.00E00 corneocyte desquamation (GO:0003336) 2 0 .00 - < 0.01 1.00E00 1.00E00 corneocyte development (GO:0003335) 3 0 .00 - < 0.01 1.00E00 1.00E00 keratinocyte development (GO:0003334) 13 0 .00 - < 0.01 1.00E00 1.00E00 amino acid transmembrane transport (GO:0003333) 101 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of extracellular matrix constituent secretion (GO:0003332) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycosphingolipid catabolic process (GO:0046479) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of extracellular matrix constituent secretion (GO:0003331) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of extracellular matrix constituent secretion (GO:0003330) 9 0 .00 - < 0.01 1.00E00 1.00E00 lactosylceramide metabolic process (GO:0046478) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycosylceramide catabolic process (GO:0046477) 6 0 .00 - < 0.01 1.00E00 1.00E00 glycosylceramide biosynthetic process (GO:0046476) 7 0 .00 - < 0.01 1.00E00 1.00E00 glycerophospholipid catabolic process (GO:0046475) 31 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to cisplatin (GO:0072719) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to cisplatin (GO:0072718) 6 0 .00 - < 0.01 1.00E00 1.00E00 glycerophospholipid biosynthetic process (GO:0046474) 188 0 .05 - < 0.01 1.00E00 1.00E00 cellular response to actinomycin D (GO:0072717) 4 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidic acid metabolic process (GO:0046473) 37 0 .01 - < 0.01 1.00E00 1.00E00 response to actinomycin D (GO:0072716) 5 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol metabolic process (GO:0046471) 34 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to selenite ion (GO:0072715) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylcholine metabolic process (GO:0046470) 69 0 .02 - < 0.01 1.00E00 1.00E00 response to selenite ion (GO:0072714) 1 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to hydroxyurea (GO:0072711) 11 0 .00 - < 0.01 1.00E00 1.00E00 response to hydroxyurea (GO:0072710) 12 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland alveolus development (GO:0060749) 20 0 .01 - < 0.01 1.00E00 1.00E00 tertiary branching involved in mammary gland duct morphogenesis (GO:0060748) 3 0 .00 - < 0.01 1.00E00 1.00E00 parental behavior (GO:0060746) 15 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland branching involved in pregnancy (GO:0060745) 7 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland branching involved in thelarche (GO:0060744) 5 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell maturation involved in prostate gland development (GO:0060743) 3 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in prostate gland development (GO:0060742) 11 0 .00 - < 0.01 1.00E00 1.00E00 prostate gland stromal morphogenesis (GO:0060741) 3 0 .00 - < 0.01 1.00E00 1.00E00 prostate gland epithelium morphogenesis (GO:0060740) 23 0 .01 - < 0.01 1.00E00 1.00E00 pancreatic PP cell fate commitment (GO:0003329) 2 0 .00 - < 0.01 1.00E00 1.00E00 type B pancreatic cell fate commitment (GO:0003327) 1 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic A cell fate commitment (GO:0003326) 2 0 .00 - < 0.01 1.00E00 1.00E00 type B pancreatic cell development (GO:0003323) 16 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic A cell development (GO:0003322) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of blood pressure by epinephrine-norepinephrine (GO:0003321) 4 0 .00 - < 0.01 1.00E00 1.00E00 platelet activating factor metabolic process (GO:0046469) 8 0 .00 - < 0.01 1.00E00 1.00E00 membrane lipid biosynthetic process (GO:0046467) 145 0 .04 - < 0.01 1.00E00 1.00E00 membrane lipid catabolic process (GO:0046466) 48 0 .01 - < 0.01 1.00E00 1.00E00 dolichyl diphosphate metabolic process (GO:0046465) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to sorbitol (GO:0072709) 4 0 .00 - < 0.01 1.00E00 1.00E00 acylglycerol catabolic process (GO:0046464) 33 0 .01 - < 0.01 1.00E00 1.00E00 response to sorbitol (GO:0072708) 6 0 .00 - < 0.01 1.00E00 1.00E00 acylglycerol biosynthetic process (GO:0046463) 29 0 .01 - < 0.01 1.00E00 1.00E00 cellular response to sodium dodecyl sulfate (GO:0072707) 1 0 .00 - < 0.01 1.00E00 1.00E00 monoacylglycerol metabolic process (GO:0046462) 16 0 .00 - < 0.01 1.00E00 1.00E00 response to sodium dodecyl sulfate (GO:0072706) 1 0 .00 - < 0.01 1.00E00 1.00E00 neutral lipid catabolic process (GO:0046461) 33 0 .01 - < 0.01 1.00E00 1.00E00 neutral lipid biosynthetic process (GO:0046460) 29 0 .01 - < 0.01 1.00E00 1.00E00 late endosome to Golgi transport (GO:0034499) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to methyl methanesulfonate (GO:0072703) 1 0 .00 - < 0.01 1.00E00 1.00E00 early endosome to Golgi transport (GO:0034498) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to methyl methanesulfonate (GO:0072702) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to phagophore assembly site (GO:0034497) 16 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal-epithelial cell signaling involved in prostate gland development (GO:0060739) 2 0 .00 - < 0.01 1.00E00 1.00E00 epithelial-mesenchymal signaling involved in prostate gland development (GO:0060738) 1 0 .00 - < 0.01 1.00E00 1.00E00 prostate gland morphogenetic growth (GO:0060737) 4 0 .00 - < 0.01 1.00E00 1.00E00 prostate gland growth (GO:0060736) 11 1 .00 + > 100 3.20E-03 1.00E00 regulation of eIF2 alpha phosphorylation by dsRNA (GO:0060735) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation (GO:0060734) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inositol phosphate biosynthetic process (GO:0060732) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of intestinal epithelial structure maintenance (GO:0060731) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of intestinal epithelial structure maintenance (GO:0060730) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell migration to the midline involved in heart development (GO:0003318) 1 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic PP cell differentiation (GO:0003312) 2 0 .00 - < 0.01 1.00E00 1.00E00 short-chain fatty acid metabolic process (GO:0046459) 16 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic D cell differentiation (GO:0003311) 2 0 .00 - < 0.01 1.00E00 1.00E00 pancreatic A cell differentiation (GO:0003310) 10 0 .00 - < 0.01 1.00E00 1.00E00 hexadecanal metabolic process (GO:0046458) 1 0 .00 - < 0.01 1.00E00 1.00E00 prostanoid biosynthetic process (GO:0046457) 22 0 .01 - < 0.01 1.00E00 1.00E00 icosanoid biosynthetic process (GO:0046456) 51 0 .01 - < 0.01 1.00E00 1.00E00 dihydrofolate metabolic process (GO:0046452) 3 0 .00 - < 0.01 1.00E00 1.00E00 T cell proliferation (GO:0042098) 75 0 .02 - < 0.01 1.00E00 1.00E00 vacuolar transmembrane transport (GO:0034486) 9 0 .00 - < 0.01 1.00E00 1.00E00 intestinal epithelial structure maintenance (GO:0060729) 7 0 .00 - < 0.01 1.00E00 1.00E00 T-helper cell differentiation (GO:0042093) 49 0 .01 - < 0.01 1.00E00 1.00E00 type 2 immune response (GO:0042092) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in embryonic placenta development (GO:0060723) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of spongiotrophoblast cell proliferation (GO:0060721) 1 0 .00 - < 0.01 1.00E00 1.00E00 type B pancreatic cell differentiation (GO:0003309) 22 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of Wnt signaling pathway involved in heart development (GO:0003308) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Wnt signaling pathway involved in heart development (GO:0003307) 1 0 .00 - < 0.01 1.00E00 1.00E00 physiological cardiac muscle hypertrophy (GO:0003301) 7 0 .00 - < 0.01 1.00E00 1.00E00 creatinine metabolic process (GO:0046449) 2 0 .00 - < 0.01 1.00E00 1.00E00 tropane alkaloid metabolic process (GO:0046448) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle hypertrophy (GO:0003300) 32 0 .01 - < 0.01 1.00E00 1.00E00 FMN metabolic process (GO:0046444) 1 0 .00 - < 0.01 1.00E00 1.00E00 FAD metabolic process (GO:0046443) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine metabolic process (GO:0046440) 4 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 1 type immune response (GO:0042088) 24 0 .01 - < 0.01 1.00E00 1.00E00 pilomotor reflex (GO:0097195) 3 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylglycerol catabolic process (GO:0034478) 2 0 .00 - < 0.01 1.00E00 1.00E00 execution phase of apoptosis (GO:0097194) 51 0 .01 - < 0.01 1.00E00 1.00E00 U6 snRNA 3'-end processing (GO:0034477) 2 0 .00 - < 0.01 1.00E00 1.00E00 intrinsic apoptotic signaling pathway (GO:0097193) 177 0 .05 - < 0.01 1.00E00 1.00E00 U5 snRNA 3'-end processing (GO:0034476) 3 0 .00 - < 0.01 1.00E00 1.00E00 extrinsic apoptotic signaling pathway in absence of ligand (GO:0097192) 32 0 .01 - < 0.01 1.00E00 1.00E00 U4 snRNA 3'-end processing (GO:0034475) 8 0 .00 - < 0.01 1.00E00 1.00E00 chorionic trophoblast cell development (GO:0060719) 1 0 .00 - < 0.01 1.00E00 1.00E00 extrinsic apoptotic signaling pathway (GO:0097191) 114 0 .03 - < 0.01 1.00E00 1.00E00 chorionic trophoblast cell differentiation (GO:0060718) 7 0 .00 - < 0.01 1.00E00 1.00E00 U2 snRNA 3'-end processing (GO:0034474) 1 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic signaling pathway (GO:0097190) 331 0 .10 - < 0.01 1.00E00 1.00E00 chorion development (GO:0060717) 10 0 .00 - < 0.01 1.00E00 1.00E00 U1 snRNA 3'-end processing (GO:0034473) 3 0 .00 - < 0.01 1.00E00 1.00E00 labyrinthine layer blood vessel development (GO:0060716) 19 0 .01 - < 0.01 1.00E00 1.00E00 snRNA 3'-end processing (GO:0034472) 23 0 .01 - < 0.01 1.00E00 1.00E00 syncytiotrophoblast cell differentiation involved in labyrinthine layer development (GO:0060715) 3 0 .00 - < 0.01 1.00E00 1.00E00 labyrinthine layer morphogenesis (GO:0060713) 22 0 .01 - < 0.01 1.00E00 1.00E00 spongiotrophoblast layer development (GO:0060712) 1 0 .00 - < 0.01 1.00E00 1.00E00 labyrinthine layer development (GO:0060711) 46 0 .01 - < 0.01 1.00E00 1.00E00 cardiac muscle hypertrophy in response to stress (GO:0014898) 15 0 .00 - < 0.01 1.00E00 1.00E00 chorio-allantoic fusion (GO:0060710) 7 0 .00 - < 0.01 1.00E00 1.00E00 striated muscle hypertrophy (GO:0014897) 33 0 .01 - < 0.01 1.00E00 1.00E00 muscle hypertrophy (GO:0014896) 35 0 .01 - < 0.01 1.00E00 1.00E00 smooth muscle hypertrophy (GO:0014895) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to denervation involved in regulation of muscle adaptation (GO:0014894) 8 0 .00 - < 0.01 1.00E00 1.00E00 striated muscle atrophy (GO:0014891) 8 0 .00 - < 0.01 1.00E00 1.00E00 L-cysteine metabolic process (GO:0046439) 4 0 .00 - < 0.01 1.00E00 1.00E00 D-amino acid biosynthetic process (GO:0046437) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-alanine metabolic process (GO:0046436) 1 0 .00 - < 0.01 1.00E00 1.00E00 organophosphate catabolic process (GO:0046434) 187 0 .05 - < 0.01 1.00E00 1.00E00 dentin mineralization (GO:0097188) 1 0 .00 - < 0.01 1.00E00 1.00E00 dentinogenesis (GO:0097187) 6 0 .00 - < 0.01 1.00E00 1.00E00 amelogenesis (GO:0097186) 24 0 .01 - < 0.01 1.00E00 1.00E00 germ-line stem cell division (GO:0042078) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to azide (GO:0097184) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in gastrulation (GO:0042074) 13 0 .00 - < 0.01 1.00E00 1.00E00 response to carbon monoxide (GO:0034465) 2 0 .00 - < 0.01 1.00E00 1.00E00 intraciliary transport (GO:0042073) 50 0 .01 - < 0.01 1.00E00 1.00E00 trophoblast giant cell differentiation (GO:0060707) 11 0 .00 - < 0.01 1.00E00 1.00E00 90S preribosome assembly (GO:0034463) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell differentiation involved in embryonic placenta development (GO:0060706) 23 0 .01 - < 0.01 1.00E00 1.00E00 small-subunit processome assembly (GO:0034462) 3 0 .00 - < 0.01 1.00E00 1.00E00 muscle atrophy (GO:0014889) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of endoribonuclease activity (GO:0060702) 1 0 .00 - < 0.01 1.00E00 1.00E00 striated muscle adaptation (GO:0014888) 30 0 .01 - < 0.01 1.00E00 1.00E00 cardiac muscle adaptation (GO:0014887) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ribonuclease activity (GO:0060700) 6 0 .00 - < 0.01 1.00E00 1.00E00 transition between slow and fast fiber (GO:0014886) 1 0 .00 - < 0.01 1.00E00 1.00E00 transition between fast and slow fiber (GO:0014883) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of receptor signaling pathway via JAK-STAT (GO:0046427) 41 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of receptor signaling pathway via JAK-STAT (GO:0046426) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of receptor signaling pathway via JAK-STAT (GO:0046425) 71 0 .02 - < 0.01 1.00E00 1.00E00 ruffle assembly (GO:0097178) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of catecholamine metabolic process (GO:0042069) 19 0 .01 - < 0.01 1.00E00 1.00E00 epoxide metabolic process (GO:0097176) 5 0 .00 - < 0.01 1.00E00 1.00E00 gliogenesis (GO:0042063) 277 0 .08 - < 0.01 1.00E00 1.00E00 microtubule anchoring at centrosome (GO:0034454) 11 0 .00 - < 0.01 1.00E00 1.00E00 microtubule anchoring (GO:0034453) 24 0 .01 - < 0.01 1.00E00 1.00E00 wound healing (GO:0042060) 334 0 .10 - < 0.01 1.00E00 1.00E00 myeloid cell differentiation (GO:0030099) 307 0 .09 - < 0.01 1.00E00 1.00E00 lymphocyte differentiation (GO:0030098) 281 0 .08 - < 0.01 1.00E00 1.00E00 hemopoiesis (GO:0030097) 694 0 .20 - < 0.01 1.00E00 1.00E00 response to electrical stimulus involved in regulation of muscle adaptation (GO:0014878) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to muscle inactivity involved in regulation of muscle adaptation (GO:0014877) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to injury involved in regulation of muscle adaptation (GO:0014876) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to stimulus involved in regulation of muscle adaptation (GO:0014874) 14 0 .00 - < 0.01 1.00E00 1.00E00 protein repair (GO:0030091) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to muscle activity involved in regulation of muscle adaptation (GO:0014873) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to muscle inactivity (GO:0014870) 9 0 .00 - < 0.01 1.00E00 1.00E00 D-amino acid metabolic process (GO:0046416) 4 0 .00 - < 0.01 1.00E00 1.00E00 urate metabolic process (GO:0046415) 12 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal stem cell proliferation (GO:0097168) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of epidermal growth factor receptor signaling pathway (GO:0042059) 28 0 .01 - < 0.01 1.00E00 1.00E00 circadian regulation of translation (GO:0097167) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epidermal growth factor receptor signaling pathway (GO:0042058) 64 0 .02 - < 0.01 1.00E00 1.00E00 ammonium ion metabolic process (GO:0097164) 22 0 .01 - < 0.01 1.00E00 1.00E00 very-low-density lipoprotein particle clearance (GO:0034447) 3 0 .00 - < 0.01 1.00E00 1.00E00 substrate adhesion-dependent cell spreading (GO:0034446) 46 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of plasma lipoprotein oxidation (GO:0034445) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dopamine metabolic process (GO:0042053) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of plasma lipoprotein oxidation (GO:0034444) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein oxidation (GO:0034443) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein oxidation (GO:0034442) 2 0 .00 - < 0.01 1.00E00 1.00E00 plasma lipoprotein particle oxidation (GO:0034441) 1 0 .00 - < 0.01 1.00E00 1.00E00 lipid oxidation (GO:0034440) 88 0 .03 - < 0.01 1.00E00 1.00E00 skeletal myofibril assembly (GO:0014866) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by chemo-mechanical energy conversion (GO:0014862) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction via regulation of action potential (GO:0014861) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter secretion involved in regulation of skeletal muscle contraction (GO:0014860) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of central B cell tolerance induction (GO:0002897) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of central B cell tolerance induction (GO:0002895) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type II hypersensitivity (GO:0002894) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type II hypersensitivity (GO:0002893) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type II hypersensitivity (GO:0002892) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immunoglobulin mediated immune response (GO:0002891) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of immunoglobulin mediated immune response (GO:0002890) 14 0 .00 - < 0.01 1.00E00 1.00E00 olfactory behavior (GO:0042048) 11 0 .00 - < 0.01 1.00E00 1.00E00 lipoprotein lipid oxidation (GO:0034439) 1 0 .00 - < 0.01 1.00E00 1.00E00 fasciculation of motor neuron axon (GO:0097156) 2 0 .00 - < 0.01 1.00E00 1.00E00 fasciculation of sensory neuron axon (GO:0097155) 3 0 .00 - < 0.01 1.00E00 1.00E00 GABAergic neuron differentiation (GO:0097154) 20 0 .01 - < 0.01 1.00E00 1.00E00 epithelial fluid transport (GO:0042045) 13 0 .00 - < 0.01 1.00E00 1.00E00 glycoprotein transport (GO:0034436) 3 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell apoptotic process (GO:0097152) 12 0 .00 - < 0.01 1.00E00 1.00E00 fluid transport (GO:0042044) 38 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of inhibitory postsynaptic potential (GO:0097151) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuronal stem cell population maintenance (GO:0097150) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of skeletal muscle cell proliferation (GO:0014859) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle cell proliferation (GO:0014858) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle cell proliferation (GO:0014857) 16 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle cell proliferation (GO:0014856) 11 0 .00 - < 0.01 1.00E00 1.00E00 insulin secretion (GO:0030073) 48 0 .01 - < 0.01 1.00E00 1.00E00 striated muscle cell proliferation (GO:0014855) 36 0 .01 - < 0.01 1.00E00 1.00E00 peptide hormone secretion (GO:0030072) 73 0 .02 - < 0.01 1.00E00 1.00E00 response to inactivity (GO:0014854) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic metaphase/anaphase transition (GO:0030071) 93 0 .03 - < 0.01 1.00E00 1.00E00 regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction (GO:0014853) 1 0 .00 - < 0.01 1.00E00 1.00E00 insulin processing (GO:0030070) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction (GO:0014852) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to muscle activity (GO:0014850) 32 0 .01 - < 0.01 1.00E00 1.00E00 proteasomal ubiquitin-independent protein catabolic process (GO:0010499) 4 0 .00 - < 0.01 1.00E00 1.00E00 proteasomal protein catabolic process (GO:0010498) 453 0 .13 - < 0.01 1.00E00 1.00E00 regulation of immunoglobulin mediated immune response (GO:0002889) 62 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid leukocyte mediated immunity (GO:0002888) 21 0 .01 - < 0.01 1.00E00 1.00E00 intercellular transport (GO:0010496) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid leukocyte mediated immunity (GO:0002887) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myeloid leukocyte mediated immunity (GO:0002886) 57 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of hypersensitivity (GO:0002885) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hypersensitivity (GO:0002884) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hypersensitivity (GO:0002883) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002882) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chronic inflammatory response to non-antigenic stimulus (GO:0002880) 1 0 .00 - < 0.01 1.00E00 1.00E00 post-translational protein acetylation (GO:0034421) 3 0 .00 - < 0.01 1.00E00 1.00E00 ureter smooth muscle contraction (GO:0014849) 2 0 .00 - < 0.01 1.00E00 1.00E00 urinary tract smooth muscle contraction (GO:0014848) 9 0 .00 - < 0.01 1.00E00 1.00E00 esophagus smooth muscle contraction (GO:0014846) 2 0 .00 - < 0.01 1.00E00 1.00E00 growth factor dependent regulation of skeletal muscle satellite cell proliferation (GO:0014843) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle satellite cell proliferation (GO:0014842) 12 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell proliferation (GO:0014841) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of acute inflammatory response to non-antigenic stimulus (GO:0002879) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acute inflammatory response to non-antigenic stimulus (GO:0002877) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of chronic inflammatory response to antigenic stimulus (GO:0002876) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chronic inflammatory response to antigenic stimulus (GO:0002875) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chronic inflammatory response to antigenic stimulus (GO:0002874) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of epidermal cell division (GO:0010482) 3 0 .00 - < 0.01 1.00E00 1.00E00 epidermal cell division (GO:0010481) 1 0 .00 - < 0.01 1.00E00 1.00E00 T cell anergy (GO:0002870) 4 0 .00 - < 0.01 1.00E00 1.00E00 urate biosynthetic process (GO:0034418) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein refolding (GO:0042026) 25 0 .01 - < 0.01 1.00E00 1.00E00 DNA endoreduplication (GO:0042023) 1 0 .00 - < 0.01 1.00E00 1.00E00 myoblast migration involved in skeletal muscle regeneration (GO:0014839) 4 0 .00 - < 0.01 1.00E00 1.00E00 myoblast differentiation involved in skeletal muscle regeneration (GO:0014835) 2 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration (GO:0014834) 5 0 .00 - < 0.01 1.00E00 1.00E00 urinary bladder smooth muscle contraction (GO:0014832) 7 0 .00 - < 0.01 1.00E00 1.00E00 vesicle transport along actin filament (GO:0030050) 5 0 .00 - < 0.01 1.00E00 1.00E00 gastro-intestinal system smooth muscle contraction (GO:0014831) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of acute inflammatory response to antigenic stimulus (GO:0002866) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of acute inflammatory response to antigenic stimulus (GO:0002865) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of acute inflammatory response to antigenic stimulus (GO:0002864) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of inflammatory response to antigenic stimulus (GO:0002863) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of inflammatory response to antigenic stimulus (GO:0002862) 29 0 .01 - < 0.01 1.00E00 1.00E00 regulation of gastrulation (GO:0010470) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of inflammatory response to antigenic stimulus (GO:0002861) 44 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002860) 6 0 .00 - < 0.01 1.00E00 1.00E00 response to fluid shear stress (GO:0034405) 46 0 .01 - < 0.01 1.00E00 1.00E00 nucleobase-containing small molecule biosynthetic process (GO:0034404) 19 0 .01 - < 0.01 1.00E00 1.00E00 receptor localization to synapse (GO:0097120) 48 0 .01 - < 0.01 1.00E00 1.00E00 muscle filament sliding (GO:0030049) 15 0 .00 - < 0.01 1.00E00 1.00E00 actin filament-based movement (GO:0030048) 105 0 .03 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle contraction (GO:0014829) 16 0 .00 - < 0.01 1.00E00 1.00E00 actin modification (GO:0030047) 4 0 .00 - < 0.01 1.00E00 1.00E00 parallel actin filament bundle assembly (GO:0030046) 7 0 .00 - < 0.01 1.00E00 1.00E00 intestine smooth muscle contraction (GO:0014827) 5 0 .00 - < 0.01 1.00E00 1.00E00 vein smooth muscle contraction (GO:0014826) 4 0 .00 - < 0.01 1.00E00 1.00E00 actin filament fragmentation (GO:0030043) 4 0 .00 - < 0.01 1.00E00 1.00E00 actin filament depolymerization (GO:0030042) 12 0 .00 - < 0.01 1.00E00 1.00E00 artery smooth muscle contraction (GO:0014824) 9 0 .00 - < 0.01 1.00E00 1.00E00 actin filament polymerization (GO:0030041) 33 0 .01 - < 0.01 1.00E00 1.00E00 response to activity (GO:0014823) 82 0 .02 - < 0.01 1.00E00 1.00E00 detection of wounding (GO:0014822) 1 0 .00 - < 0.01 1.00E00 1.00E00 phasic smooth muscle contraction (GO:0014821) 21 0 .01 - < 0.01 1.00E00 1.00E00 tonic smooth muscle contraction (GO:0014820) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of signaling receptor activity (GO:0010469) 71 0 .02 - < 0.01 1.00E00 1.00E00 regulation of gene expression (GO:0010468) 4979 0 1.45 - < 0.01 3.47E-01 1.00E00 negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002859) 3 0 .00 - < 0.01 1.00E00 1.00E00 gene expression (GO:0010467) 2501 1 .73 + 1.37 5.40E-01 1.00E00 regulation of natural killer cell mediated cytotoxicity directed against tumor cell target (GO:0002858) 9 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of peptidase activity (GO:0010466) 29 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell mediated immune response to tumor cell (GO:0002857) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell mediated immune response to tumor cell (GO:0002856) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mesenchymal cell proliferation (GO:0010464) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell mediated immune response to tumor cell (GO:0002855) 10 0 .00 - < 0.01 1.00E00 1.00E00 mesenchymal cell proliferation (GO:0010463) 27 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002854) 2 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic density protein 95 clustering (GO:0097119) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated cytotoxicity directed against tumor cell target (GO:0002852) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of heart rate (GO:0010460) 26 0 .01 - < 0.01 1.00E00 1.00E00 neuroligin clustering involved in postsynaptic membrane assembly (GO:0097118) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peripheral T cell tolerance induction (GO:0002851) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA replication (GO:0008156) 24 0 .01 - < 0.01 1.00E00 1.00E00 guanylate kinase-associated protein clustering (GO:0097117) 2 0 .00 - < 0.01 1.00E00 1.00E00 gephyrin clustering involved in postsynaptic density assembly (GO:0097116) 5 0 .00 - < 0.01 1.00E00 1.00E00 actin polymerization or depolymerization (GO:0008154) 59 0 .02 - < 0.01 1.00E00 1.00E00 neurexin clustering involved in presynaptic membrane assembly (GO:0097115) 1 0 .00 - < 0.01 1.00E00 1.00E00 NMDA glutamate receptor clustering (GO:0097114) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of embryonic development (GO:0045995) 91 0 .03 - < 0.01 1.00E00 1.00E00 metabolic process (GO:0008152) 7621 6 2.22 + 2.70 2.58E-03 1.00E00 positive regulation of translational initiation by iron (GO:0045994) 1 0 .00 - < 0.01 1.00E00 1.00E00 AMPA glutamate receptor clustering (GO:0097113) 5 0 .00 - < 0.01 1.00E00 1.00E00 gamma-aminobutyric acid receptor clustering (GO:0097112) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of translational initiation by iron (GO:0045993) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of embryonic development (GO:0045992) 2 0 .00 - < 0.01 1.00E00 1.00E00 biological_process (GO:0008150) 17701 6 5.16 + 1.16 1.00E00 1.00E00 endoplasmic reticulum-Golgi intermediate compartment organization (GO:0097111) 2 0 .00 - < 0.01 1.00E00 1.00E00 carbon catabolite activation of transcription (GO:0045991) 7 0 .00 - < 0.01 1.00E00 1.00E00 carbon catabolite regulation of transcription (GO:0045990) 7 0 .00 - < 0.01 1.00E00 1.00E00 contractile actin filament bundle assembly (GO:0030038) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction (GO:0014819) 19 0 .01 - < 0.01 1.00E00 1.00E00 actin cytoskeleton organization (GO:0030036) 544 0 .16 - < 0.01 1.00E00 1.00E00 microspike assembly (GO:0030035) 4 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell differentiation (GO:0014816) 7 0 .00 - < 0.01 1.00E00 1.00E00 microvillar actin bundle assembly (GO:0030034) 1 0 .00 - < 0.01 1.00E00 1.00E00 microvillus assembly (GO:0030033) 11 0 .00 - < 0.01 1.00E00 1.00E00 lamellipodium assembly (GO:0030032) 36 0 .01 - < 0.01 1.00E00 1.00E00 cell projection assembly (GO:0030031) 458 0 .13 - < 0.01 1.00E00 1.00E00 cell projection organization (GO:0030030) 1237 0 .36 - < 0.01 1.00E00 1.00E00 muscle cell migration (GO:0014812) 28 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of heart rate (GO:0010459) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion (GO:0014810) 1 0 .00 - < 0.01 1.00E00 1.00E00 exit from mitosis (GO:0010458) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of peripheral T cell tolerance induction (GO:0002849) 1 0 .00 - < 0.01 1.00E00 1.00E00 centriole-centriole cohesion (GO:0010457) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell fate commitment (GO:0010455) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell fate commitment (GO:0010454) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell fate commitment (GO:0010453) 45 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated immune response to tumor cell (GO:0002842) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of striated muscle contraction (GO:0045989) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell mediated immune response to tumor cell (GO:0002841) 5 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic density assembly (GO:0097107) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of striated muscle contraction (GO:0045988) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated immune response to tumor cell (GO:0002840) 15 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic density organization (GO:0097106) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle contraction (GO:0045987) 31 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle contraction (GO:0045986) 13 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic membrane assembly (GO:0097105) 9 0 .00 - < 0.01 1.00E00 1.00E00 postsynaptic membrane assembly (GO:0097104) 8 0 .00 - < 0.01 1.00E00 1.00E00 endothelial tip cell fate specification (GO:0097102) 2 0 .00 - < 0.01 1.00E00 1.00E00 blood vessel endothelial cell fate specification (GO:0097101) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleotide metabolic process (GO:0045981) 40 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of nucleotide metabolic process (GO:0045980) 28 0 .01 - < 0.01 1.00E00 1.00E00 actin filament-based process (GO:0030029) 616 0 .18 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion (GO:0014809) 5 0 .00 - < 0.01 1.00E00 1.00E00 release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0014808) 9 0 .00 - < 0.01 1.00E00 1.00E00 intracellular manganese ion homeostasis (GO:0030026) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of somitogenesis (GO:0014807) 6 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle hyperplasia (GO:0014806) 2 0 .00 - < 0.01 1.00E00 1.00E00 reproductive process (GO:0022414) 1551 1 .45 + 2.21 3.75E-01 1.00E00 smooth muscle adaptation (GO:0014805) 7 0 .00 - < 0.01 1.00E00 1.00E00 cellular process involved in reproduction in multicellular organism (GO:0022412) 417 0 .12 - < 0.01 1.00E00 1.00E00 cellular component disassembly (GO:0022411) 302 0 .09 - < 0.01 1.00E00 1.00E00 circadian sleep/wake cycle process (GO:0022410) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of immune response to tumor cell (GO:0002839) 18 0 .01 - < 0.01 1.00E00 1.00E00 response to acidic pH (GO:0010447) 29 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of immune response to tumor cell (GO:0002838) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of immune response to tumor cell (GO:0002837) 27 0 .01 - < 0.01 1.00E00 1.00E00 response to alkaline pH (GO:0010446) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of response to tumor cell (GO:0002836) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of response to tumor cell (GO:0002835) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to tumor cell (GO:0002834) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of response to biotic stimulus (GO:0002833) 335 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of response to biotic stimulus (GO:0002832) 131 0 .04 - < 0.01 1.00E00 1.00E00 fungiform papilla formation (GO:0061198) 3 0 .00 - < 0.01 1.00E00 1.00E00 fungiform papilla morphogenesis (GO:0061197) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to biotic stimulus (GO:0002831) 567 0 .17 - < 0.01 1.00E00 1.00E00 fungiform papilla development (GO:0061196) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type 2 immune response (GO:0002830) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle, embryonic (GO:0045977) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic cell cycle, embryonic (GO:0045976) 2 0 .00 - < 0.01 1.00E00 1.00E00 taste bud development (GO:0061193) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of sclerotome development (GO:0061190) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell-cell adhesion (GO:0022409) 336 0 .10 - < 0.01 1.00E00 1.00E00 negative regulation of cell-cell adhesion (GO:0022408) 200 0 .06 - < 0.01 1.00E00 1.00E00 regulation of cell-cell adhesion (GO:0022407) 504 0 .15 - < 0.01 1.00E00 1.00E00 membrane docking (GO:0022406) 88 0 .03 - < 0.01 1.00E00 1.00E00 hair cycle process (GO:0022405) 87 0 .03 - < 0.01 1.00E00 1.00E00 molting cycle process (GO:0022404) 87 0 .03 - < 0.01 1.00E00 1.00E00 maintenance of cell polarity (GO:0030011) 14 0 .00 - < 0.01 1.00E00 1.00E00 cell cycle process (GO:0022402) 897 0 .26 - < 0.01 1.00E00 1.00E00 establishment of cell polarity (GO:0030010) 140 0 .04 - < 0.01 1.00E00 1.00E00 negative adaptation of signaling pathway (GO:0022401) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of opsin-mediated signaling pathway (GO:0022400) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type 2 immune response (GO:0002829) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of type 2 immune response (GO:0002828) 34 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of T-helper 1 type immune response (GO:0002827) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of T-helper 1 type immune response (GO:0002826) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T-helper 1 type immune response (GO:0002825) 32 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002824) 129 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of sclerotome development (GO:0061189) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002823) 63 0 .02 - < 0.01 1.00E00 1.00E00 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains (GO:0002822) 204 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of rDNA heterochromatin formation (GO:0061188) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of adaptive immune response (GO:0002821) 135 0 .04 - < 0.01 1.00E00 1.00E00 regulation of rDNA heterochromatin formation (GO:0061187) 2 0 .00 - < 0.01 1.00E00 1.00E00 fatty acid omega-oxidation (GO:0010430) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adaptive immune response (GO:0002820) 68 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of dermatome development (GO:0061185) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of growth rate (GO:0045967) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dermatome development (GO:0061184) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dermatome development (GO:0061183) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of chondrocyte development (GO:0061182) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dopamine metabolic process (GO:0045964) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chondrocyte development (GO:0061181) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dopamine metabolic process (GO:0045963) 3 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland epithelium development (GO:0061180) 59 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of complement activation, classical pathway (GO:0045960) 1 0 .00 - < 0.01 1.00E00 1.00E00 intracellular potassium ion homeostasis (GO:0030007) 17 0 .00 - < 0.01 1.00E00 1.00E00 response to lipid (GO:0033993) 862 2 .25 + 7.96 2.35E-02 1.00E00 intracellular monoatomic cation homeostasis (GO:0030003) 432 0 .13 - < 0.01 1.00E00 1.00E00 intracellular monoatomic anion homeostasis (GO:0030002) 10 0 .00 - < 0.01 1.00E00 1.00E00 metal ion transport (GO:0030001) 653 0 .19 - < 0.01 1.00E00 1.00E00 regulation of adaptive immune response (GO:0002819) 219 0 .06 - < 0.01 1.00E00 1.00E00 regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria (GO:0002816) 1 0 .00 - < 0.01 1.00E00 1.00E00 biosynthetic process of antibacterial peptides active against Gram-positive bacteria (GO:0002815) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061179) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of insulin secretion involved in cellular response to glucose stimulus (GO:0061178) 60 0 .02 - < 0.01 1.00E00 1.00E00 hydrogen peroxide-mediated programmed cell death (GO:0010421) 3 0 .00 - < 0.01 1.00E00 1.00E00 biosynthetic process of antibacterial peptides active against Gram-negative bacteria (GO:0002812) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of complement activation, classical pathway (GO:0045959) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of complement activation, alternative pathway (GO:0045957) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcium ion-dependent exocytosis (GO:0045956) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of calcium ion-dependent exocytosis (GO:0045955) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of establishment of bipolar cell polarity (GO:0061172) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) 28 0 .01 - < 0.01 1.00E00 1.00E00 establishment of bipolar cell polarity (GO:0061171) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell mediated cytotoxicity (GO:0045953) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of hair follicle placode formation (GO:0061170) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic recombination (GO:0045951) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic recombination (GO:0045950) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antibacterial peptide biosynthetic process (GO:0002808) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial peptide biosynthetic process (GO:0002807) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial peptide biosynthetic process (GO:0002805) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of antibacterial peptide production (GO:0002803) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of hair follicle placode formation (GO:0061168) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational initiation (GO:0045948) 30 0 .01 - < 0.01 1.00E00 1.00E00 response to 11-deoxycorticosterone (GO:1903496) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of translational initiation (GO:0045947) 24 0 .01 - < 0.01 1.00E00 1.00E00 protein localization (GO:0008104) 1964 0 .57 - < 0.01 1.00E00 1.00E00 cellular response to dehydroepiandrosterone (GO:1903495) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to dehydroepiandrosterone (GO:1903494) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by RNA polymerase III (GO:0045945) 19 0 .01 - < 0.01 1.00E00 1.00E00 endoplasmic reticulum polarization (GO:0061163) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of monopolar cell polarity (GO:0061162) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by RNA polymerase II (GO:0045944) 1234 0 .36 - < 0.01 1.00E00 1.00E00 positive regulation of transcription by RNA polymerase I (GO:0045943) 36 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cytokinesis (GO:1903490) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of steroid metabolic process (GO:0045940) 34 0 .01 - < 0.01 1.00E00 1.00E00 box H/ACA sno(s)RNA metabolic process (GO:0033979) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of bipolar cell polarity involved in cell morphogenesis (GO:0061159) 2 0 .00 - < 0.01 1.00E00 1.00E00 3'-UTR-mediated mRNA destabilization (GO:0061158) 19 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of lactation (GO:1903489) 2 0 .00 - < 0.01 1.00E00 1.00E00 mRNA destabilization (GO:0061157) 78 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of steroid metabolic process (GO:0045939) 28 0 .01 - < 0.01 1.00E00 1.00E00 choline metabolic process (GO:0019695) 6 0 .00 - < 0.01 1.00E00 1.00E00 pulmonary artery morphogenesis (GO:0061156) 6 0 .00 - < 0.01 1.00E00 1.00E00 alkanesulfonate metabolic process (GO:0019694) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lactation (GO:1903487) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of circadian sleep/wake cycle, sleep (GO:0045938) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phosphate metabolic process (GO:0045937) 398 0 .12 - < 0.01 1.00E00 1.00E00 ribose phosphate metabolic process (GO:0019693) 316 0 .09 - < 0.01 1.00E00 1.00E00 negative regulation of phosphate metabolic process (GO:0045936) 219 0 .06 - < 0.01 1.00E00 1.00E00 deoxyribose phosphate metabolic process (GO:0019692) 43 0 .01 - < 0.01 1.00E00 1.00E00 endothelial tube morphogenesis (GO:0061154) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of nucleobase-containing compound metabolic process (GO:0045935) 1990 0 .58 - < 0.01 1.00E00 1.00E00 trachea gland development (GO:0061153) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of nucleobase-containing compound metabolic process (GO:0045934) 1518 0 .44 - < 0.01 1.00E00 1.00E00 trachea submucosa development (GO:0061152) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of muscle contraction (GO:0045933) 49 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of muscle contraction (GO:0045932) 23 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle (GO:0045931) 124 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic cell cycle (GO:0045930) 207 0 .06 - < 0.01 1.00E00 1.00E00 box C/D sno(s)RNA metabolic process (GO:0033967) 3 0 .00 - < 0.01 1.00E00 1.00E00 P-body assembly (GO:0033962) 16 0 .00 - < 0.01 1.00E00 1.00E00 neural plate anterior/posterior regionalization (GO:0021999) 4 0 .00 - < 0.01 1.00E00 1.00E00 neural plate mediolateral regionalization (GO:0021998) 1 0 .00 - < 0.01 1.00E00 1.00E00 neural plate axis specification (GO:0021997) 2 0 .00 - < 0.01 1.00E00 1.00E00 initiation of neural tube closure (GO:0021993) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic actomyosin contractile ring assembly actin filament organization (GO:1903479) 3 0 .00 - < 0.01 1.00E00 1.00E00 Peyer's patch morphogenesis (GO:0061146) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of growth (GO:0045927) 247 0 .07 - < 0.01 1.00E00 1.00E00 lung smooth muscle development (GO:0061145) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic actomyosin contractile ring assembly (GO:1903475) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of growth (GO:0045926) 223 0 .07 - < 0.01 1.00E00 1.00E00 glyceraldehyde-3-phosphate metabolic process (GO:0019682) 12 0 .00 - < 0.01 1.00E00 1.00E00 alveolar secondary septum development (GO:0061144) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of female receptivity (GO:0045925) 3 0 .00 - < 0.01 1.00E00 1.00E00 alveolar primary septum development (GO:0061143) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of female receptivity (GO:0045924) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fatty acid metabolic process (GO:0045923) 38 0 .01 - < 0.01 1.00E00 1.00E00 lung ciliated cell differentiation (GO:0061141) 1 0 .00 - < 0.01 1.00E00 1.00E00 lung secretory cell differentiation (GO:0061140) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid metabolic process (GO:0045922) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of exocytosis (GO:0045921) 82 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of exocytosis (GO:0045920) 37 0 .01 - < 0.01 1.00E00 1.00E00 olfactory cortex development (GO:0021989) 1 0 .00 - < 0.01 1.00E00 1.00E00 olfactory lobe development (GO:0021988) 37 0 .01 - < 0.01 1.00E00 1.00E00 cerebral cortex development (GO:0021987) 132 0 .04 - < 0.01 1.00E00 1.00E00 habenula development (GO:0021986) 3 0 .00 - < 0.01 1.00E00 1.00E00 neurohypophysis development (GO:0021985) 2 0 .00 - < 0.01 1.00E00 1.00E00 adenohypophysis development (GO:0021984) 16 0 .00 - < 0.01 1.00E00 1.00E00 pituitary gland development (GO:0021983) 42 0 .01 - < 0.01 1.00E00 1.00E00 propionate metabolic process, methylmalonyl pathway (GO:0019678) 1 0 .00 - < 0.01 1.00E00 1.00E00 NAD catabolic process (GO:0019677) 3 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of a branching epithelium (GO:0061138) 166 0 .05 - < 0.01 1.00E00 1.00E00 ammonia assimilation cycle (GO:0019676) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proteasomal protein catabolic process (GO:0061136) 198 0 .06 - < 0.01 1.00E00 1.00E00 NAD metabolic process (GO:0019674) 46 0 .01 - < 0.01 1.00E00 1.00E00 GDP-mannose metabolic process (GO:0019673) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of complement activation (GO:0045917) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of complement activation (GO:0045916) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cell cycle DNA replication (GO:1903465) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic cell cycle DNA replication (GO:1903464) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of catecholamine metabolic process (GO:0045915) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cell cycle DNA replication (GO:1903463) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of catecholamine metabolic process (GO:0045914) 3 0 .00 - < 0.01 1.00E00 1.00E00 anaerobic glutamate catabolic process (GO:0019670) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of carbohydrate metabolic process (GO:0045913) 83 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of carbohydrate metabolic process (GO:0045912) 56 0 .02 - < 0.01 1.00E00 1.00E00 Okazaki fragment processing involved in mitotic DNA replication (GO:1903461) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA recombination (GO:0045911) 76 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of DNA recombination (GO:0045910) 51 0 .01 - < 0.01 1.00E00 1.00E00 hypothalamus cell differentiation (GO:0021979) 13 0 .00 - < 0.01 1.00E00 1.00E00 telencephalon regionalization (GO:0021978) 13 0 .00 - < 0.01 1.00E00 1.00E00 corticospinal neuron axon guidance through spinal cord (GO:0021972) 1 0 .00 - < 0.01 1.00E00 1.00E00 nitrogenous compound fermentation (GO:0019666) 1 0 .00 - < 0.01 1.00E00 1.00E00 anaerobic amino acid catabolic process (GO:0019665) 1 0 .00 - < 0.01 1.00E00 1.00E00 lactate catabolic process (GO:1903457) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vasoconstriction (GO:0045907) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of vasoconstriction (GO:0045906) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational termination (GO:0045905) 4 0 .00 - < 0.01 1.00E00 1.00E00 glucose catabolic process to lactate via pyruvate (GO:0019661) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycolytic fermentation (GO:0019660) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational fidelity (GO:0045903) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of G1 to G0 transition (GO:1903452) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of G1 to G0 transition (GO:1903451) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of G1 to G0 transition (GO:1903450) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of translational elongation (GO:0045901) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of translational elongation (GO:0045900) 6 0 .00 - < 0.01 1.00E00 1.00E00 corticospinal neuron axon guidance (GO:0021966) 2 0 .00 - < 0.01 1.00E00 1.00E00 spinal cord ventral commissure morphogenesis (GO:0021965) 3 0 .00 - < 0.01 1.00E00 1.00E00 glucose catabolic process to lactate (GO:0019659) 2 0 .00 - < 0.01 1.00E00 1.00E00 anterior commissure morphogenesis (GO:0021960) 7 0 .00 - < 0.01 1.00E00 1.00E00 androst-4-ene-3,17-dione biosynthetic process (GO:1903449) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of heart growth (GO:0061117) 21 0 .01 - < 0.01 1.00E00 1.00E00 lung proximal/distal axis specification (GO:0061115) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein transport from ciliary membrane to plasma membrane (GO:1903445) 2 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in pancreas morphogenesis (GO:0061114) 1 0 .00 - < 0.01 1.00E00 1.00E00 pancreas morphogenesis (GO:0061113) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of brown fat cell differentiation (GO:1903444) 4 0 .00 - < 0.01 1.00E00 1.00E00 response to lipoic acid (GO:1903442) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to ciliary membrane (GO:1903441) 10 0 .00 - < 0.01 1.00E00 1.00E00 corticospinal tract morphogenesis (GO:0021957) 8 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system interneuron axonogenesis (GO:0021956) 1 0 .00 - < 0.01 1.00E00 1.00E00 central nervous system neuron axonogenesis (GO:0021955) 37 0 .01 - < 0.01 1.00E00 1.00E00 central nervous system neuron development (GO:0021954) 95 0 .03 - < 0.01 1.00E00 1.00E00 central nervous system neuron differentiation (GO:0021953) 210 0 .06 - < 0.01 1.00E00 1.00E00 central nervous system projection neuron axonogenesis (GO:0021952) 29 0 .01 - < 0.01 1.00E00 1.00E00 aerobic electron transport chain (GO:0019646) 87 0 .03 - < 0.01 1.00E00 1.00E00 seminal vesicle epithelium development (GO:0061108) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic cytokinetic process (GO:1903438) 7 0 .00 - < 0.01 1.00E00 1.00E00 seminal vesicle development (GO:0061107) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of stomach neuroendocrine cell differentiation (GO:0061106) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic cytokinetic process (GO:1903436) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of stomach neuroendocrine cell differentiation (GO:0061105) 1 0 .00 - < 0.01 1.00E00 1.00E00 adrenal chromaffin cell differentiation (GO:0061104) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of constitutive secretory pathway (GO:1903435) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of constitutive secretory pathway (GO:1903434) 1 0 .00 - < 0.01 1.00E00 1.00E00 carotid body glomus cell differentiation (GO:0061103) 1 0 .00 - < 0.01 1.00E00 1.00E00 D-glucuronate catabolic process to D-xylulose 5-phosphate (GO:0019640) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of constitutive secretory pathway (GO:1903433) 2 0 .00 - < 0.01 1.00E00 1.00E00 stomach neuroendocrine cell differentiation (GO:0061102) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of TORC1 signaling (GO:1903432) 100 0 .03 - < 0.01 1.00E00 1.00E00 neuroendocrine cell differentiation (GO:0061101) 18 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of cell maturation (GO:1903431) 9 0 .00 - < 0.01 1.00E00 1.00E00 lung neuroendocrine cell differentiation (GO:0061100) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell maturation (GO:1903430) 8 0 .00 - < 0.01 1.00E00 1.00E00 neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration (GO:0021944) 1 0 .00 - < 0.01 1.00E00 1.00E00 formation of radial glial scaffolds (GO:0021943) 4 0 .00 - < 0.01 1.00E00 1.00E00 radial glia guided migration of Purkinje cell (GO:0021942) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to microtubule cytoskeleton (GO:0072698) 41 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cerebellar granule cell precursor proliferation (GO:0021941) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cerebellar granule cell precursor proliferation (GO:0021940) 4 0 .00 - < 0.01 1.00E00 1.00E00 organophosphate metabolic process (GO:0019637) 975 0 .28 - < 0.01 1.00E00 1.00E00 protein localization to cell cortex (GO:0072697) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell maturation (GO:1903429) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of reactive oxygen species biosynthetic process (GO:1903428) 18 0 .01 - < 0.01 1.00E00 1.00E00 regulation of DNA recombination at telomere (GO:0072695) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of reactive oxygen species biosynthetic process (GO:1903427) 17 0 .00 - < 0.01 1.00E00 1.00E00 regulation of reactive oxygen species biosynthetic process (GO:1903426) 42 0 .01 - < 0.01 1.00E00 1.00E00 fluoride transmembrane transport (GO:1903424) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle recycling (GO:1903423) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of synaptic vesicle recycling (GO:1903422) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle recycling (GO:1903421) 29 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to endoplasmic reticulum tubular network (GO:1903420) 1 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar Purkinje cell-granule cell precursor cell signaling (GO:0021937) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cerebellar granule cell precursor proliferation (GO:0021936) 7 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granule cell precursor tangential migration (GO:0021935) 2 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain tangential cell migration (GO:0021934) 5 0 .00 - < 0.01 1.00E00 1.00E00 radial glia guided migration of cerebellar granule cell (GO:0021933) 1 0 .00 - < 0.01 1.00E00 1.00E00 hindbrain radial glia guided cell migration (GO:0021932) 9 0 .00 - < 0.01 1.00E00 1.00E00 cerebellar granule cell precursor proliferation (GO:0021930) 8 0 .00 - < 0.01 1.00E00 1.00E00 urea metabolic process (GO:0019627) 13 0 .00 - < 0.01 1.00E00 1.00E00 short-chain fatty acid catabolic process (GO:0019626) 7 0 .00 - < 0.01 1.00E00 1.00E00 T cell extravasation (GO:0072683) 8 0 .00 - < 0.01 1.00E00 1.00E00 response to glycoside (GO:1903416) 6 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to bile acid (GO:1903413) 5 0 .00 - < 0.01 1.00E00 1.00E00 response to bile acid (GO:1903412) 7 0 .00 - < 0.01 1.00E00 1.00E00 muscle hypertrophy in response to stress (GO:0003299) 15 0 .00 - < 0.01 1.00E00 1.00E00 physiological muscle hypertrophy (GO:0003298) 7 0 .00 - < 0.01 1.00E00 1.00E00 atrial ventricular junction remodeling (GO:0003294) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac septum cell differentiation (GO:0003292) 5 0 .00 - < 0.01 1.00E00 1.00E00 atrial septum secundum morphogenesis (GO:0003290) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation in external granule layer (GO:0021924) 8 0 .00 - < 0.01 1.00E00 1.00E00 thymocyte migration (GO:0072679) 3 0 .00 - < 0.01 1.00E00 1.00E00 T cell migration (GO:0072678) 35 0 .01 - < 0.01 1.00E00 1.00E00 eosinophil migration (GO:0072677) 21 0 .01 - < 0.01 1.00E00 1.00E00 reactive oxygen species biosynthetic process (GO:1903409) 17 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte migration (GO:0072676) 59 0 .02 - < 0.01 1.00E00 1.00E00 osteoclast fusion (GO:0072675) 6 0 .00 - < 0.01 1.00E00 1.00E00 multinuclear osteoclast differentiation (GO:0072674) 9 0 .00 - < 0.01 1.00E00 1.00E00 catechol-containing compound catabolic process (GO:0019614) 11 0 .00 - < 0.01 1.00E00 1.00E00 lamellipodium morphogenesis (GO:0072673) 7 0 .00 - < 0.01 1.00E00 1.00E00 neutrophil extravasation (GO:0072672) 6 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to nuclear body (GO:1903405) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of renal phosphate excretion (GO:1903403) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of renal phosphate excretion (GO:1903402) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-lysine transmembrane transport (GO:1903401) 9 0 .00 - < 0.01 1.00E00 1.00E00 atrial septum primum morphogenesis (GO:0003289) 5 0 .00 - < 0.01 1.00E00 1.00E00 septum secundum development (GO:0003285) 3 0 .00 - < 0.01 1.00E00 1.00E00 septum primum development (GO:0003284) 5 0 .00 - < 0.01 1.00E00 1.00E00 atrial septum development (GO:0003283) 23 0 .01 - < 0.01 1.00E00 1.00E00 ventricular septum development (GO:0003281) 73 0 .02 - < 0.01 1.00E00 1.00E00 neural tube development (GO:0021915) 156 0 .05 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in ventral spinal cord patterning (GO:0021910) 3 0 .00 - < 0.01 1.00E00 1.00E00 phenylethylamine catabolic process (GO:0019607) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to vacuole (GO:0072666) 59 0 .02 - < 0.01 1.00E00 1.00E00 2-oxobutyrate catabolic process (GO:0019606) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to vacuole (GO:0072665) 77 0 .02 - < 0.01 1.00E00 1.00E00 butyrate metabolic process (GO:0019605) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to peroxisome (GO:0072663) 20 0 .01 - < 0.01 1.00E00 1.00E00 protein localization to peroxisome (GO:0072662) 20 0 .01 - < 0.01 1.00E00 1.00E00 maintenance of protein location in plasma membrane (GO:0072660) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endoribonuclease activity (GO:0060699) 3 0 .00 - < 0.01 1.00E00 1.00E00 mechanosensory behavior (GO:0007638) 15 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid catabolic process (GO:0060697) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipid catabolic process (GO:0060696) 7 0 .00 - < 0.01 1.00E00 1.00E00 chemosensory behavior (GO:0007635) 19 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol transporter activity (GO:0060695) 1 0 .00 - < 0.01 1.00E00 1.00E00 optokinetic behavior (GO:0007634) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching involved in salivary gland morphogenesis (GO:0060693) 9 0 .00 - < 0.01 1.00E00 1.00E00 visual behavior (GO:0007632) 59 0 .02 - < 0.01 1.00E00 1.00E00 feeding behavior (GO:0007631) 92 0 .03 - < 0.01 1.00E00 1.00E00 epithelial cell maturation involved in salivary gland development (GO:0060691) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac septum development (GO:0003279) 109 0 .03 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in salivary gland development (GO:0060690) 1 0 .00 - < 0.01 1.00E00 1.00E00 jump response (GO:0007630) 1 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process involved in heart morphogenesis (GO:0003278) 5 0 .00 - < 0.01 1.00E00 1.00E00 apoptotic process involved in outflow tract morphogenesis (GO:0003275) 2 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion fusion (GO:0003274) 5 0 .00 - < 0.01 1.00E00 1.00E00 cell migration involved in endocardial cushion formation (GO:0003273) 4 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion formation (GO:0003272) 25 0 .01 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003271) 1 0 .00 - < 0.01 1.00E00 1.00E00 Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation (GO:0003270) 1 0 .00 - < 0.01 1.00E00 1.00E00 forebrain-midbrain boundary formation (GO:0021905) 1 0 .00 - < 0.01 1.00E00 1.00E00 dorsal/ventral neural tube patterning (GO:0021904) 15 0 .00 - < 0.01 1.00E00 1.00E00 rostrocaudal neural tube patterning (GO:0021903) 11 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to plasma membrane (GO:0072659) 197 0 .06 - < 0.01 1.00E00 1.00E00 commitment of neuronal cell to specific neuron type in forebrain (GO:0021902) 6 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein location in membrane (GO:0072658) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to membrane (GO:0072657) 460 0 .13 - < 0.01 1.00E00 1.00E00 maintenance of protein location in mitochondrion (GO:0072656) 5 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to mitochondrion (GO:0072655) 78 0 .02 - < 0.01 1.00E00 1.00E00 cell differentiation involved in salivary gland development (GO:0060689) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of morphogenesis of a branching structure (GO:0060688) 55 0 .02 - < 0.01 1.00E00 1.00E00 adult walking behavior (GO:0007628) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of branching involved in prostate gland morphogenesis (GO:0060687) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of prostatic bud formation (GO:0060686) 4 0 .00 - < 0.01 1.00E00 1.00E00 locomotory behavior (GO:0007626) 208 0 .06 - < 0.01 1.00E00 1.00E00 regulation of prostatic bud formation (GO:0060685) 6 0 .00 - < 0.01 1.00E00 1.00E00 grooming behavior (GO:0007625) 15 0 .00 - < 0.01 1.00E00 1.00E00 epithelial-mesenchymal cell signaling (GO:0060684) 5 0 .00 - < 0.01 1.00E00 1.00E00 ultradian rhythm (GO:0007624) 2 0 .00 - < 0.01 1.00E00 1.00E00 circadian rhythm (GO:0007623) 140 0 .04 - < 0.01 1.00E00 1.00E00 regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling (GO:0060683) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary ureteric bud growth (GO:0060682) 1 0 .00 - < 0.01 1.00E00 1.00E00 rhythmic behavior (GO:0007622) 27 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of female receptivity (GO:0007621) 4 0 .00 - < 0.01 1.00E00 1.00E00 branch elongation involved in ureteric bud branching (GO:0060681) 1 0 .00 - < 0.01 1.00E00 1.00E00 copulation (GO:0007620) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of secondary heart field cardioblast proliferation (GO:0003266) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cardioblast proliferation (GO:0003264) 10 0 .00 - < 0.01 1.00E00 1.00E00 cardioblast migration (GO:0003260) 1 0 .00 - < 0.01 1.00E00 1.00E00 courtship behavior (GO:0007619) 3 0 .00 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in ureteric bud branching (GO:0060678) 1 0 .00 - < 0.01 1.00E00 1.00E00 mating (GO:0007618) 2 0 .00 - < 0.01 1.00E00 1.00E00 ureteric bud elongation (GO:0060677) 6 0 .00 - < 0.01 1.00E00 1.00E00 mating behavior (GO:0007617) 32 0 .01 - < 0.01 1.00E00 1.00E00 ureteric bud formation (GO:0060676) 5 0 .00 - < 0.01 1.00E00 1.00E00 long-term memory (GO:0007616) 38 0 .01 - < 0.01 1.00E00 1.00E00 ureteric bud morphogenesis (GO:0060675) 56 0 .02 - < 0.01 1.00E00 1.00E00 placenta blood vessel development (GO:0060674) 31 0 .01 - < 0.01 1.00E00 1.00E00 short-term memory (GO:0007614) 11 0 .00 - < 0.01 1.00E00 1.00E00 memory (GO:0007613) 131 0 .04 - < 0.01 1.00E00 1.00E00 learning (GO:0007612) 161 0 .05 - < 0.01 1.00E00 1.00E00 epithelial cell morphogenesis involved in placental branching (GO:0060672) 3 0 .00 - < 0.01 1.00E00 1.00E00 learning or memory (GO:0007611) 284 0 .08 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in embryonic placenta development (GO:0060671) 3 0 .00 - < 0.01 1.00E00 1.00E00 branching involved in labyrinthine layer morphogenesis (GO:0060670) 13 0 .00 - < 0.01 1.00E00 1.00E00 behavior (GO:0007610) 643 0 .19 - < 0.01 1.00E00 1.00E00 cardioblast anterior-lateral migration (GO:0003259) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane depolarization (GO:0003254) 48 0 .01 - < 0.01 1.00E00 1.00E00 cardiac neural crest cell migration involved in outflow tract morphogenesis (GO:0003253) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell proliferation involved in heart valve morphogenesis (GO:0003252) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell proliferation involved in heart valve morphogenesis (GO:0003251) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in heart valve morphogenesis (GO:0003250) 3 0 .00 - < 0.01 1.00E00 1.00E00 UDP-glucuronate metabolic process (GO:0046398) 3 0 .00 - < 0.01 1.00E00 1.00E00 carboxylic acid catabolic process (GO:0046395) 225 0 .07 - < 0.01 1.00E00 1.00E00 carboxylic acid biosynthetic process (GO:0046394) 273 0 .08 - < 0.01 1.00E00 1.00E00 5-phosphoribose 1-diphosphate metabolic process (GO:0046391) 6 0 .00 - < 0.01 1.00E00 1.00E00 ribose phosphate biosynthetic process (GO:0046390) 166 0 .05 - < 0.01 1.00E00 1.00E00 embryonic placenta morphogenesis (GO:0060669) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling (GO:0060668) 1 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of smell (GO:0007608) 472 0 .14 - < 0.01 1.00E00 1.00E00 negative regulation of phospholipid efflux (GO:1902999) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of neurofibrillary tangle assembly (GO:1902998) 2 0 .00 - < 0.01 1.00E00 1.00E00 branch elongation involved in salivary gland morphogenesis (GO:0060667) 2 0 .00 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in salivary gland branching (GO:0060666) 4 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of chemical stimulus (GO:0007606) 547 0 .16 - < 0.01 1.00E00 1.00E00 negative regulation of neurofibrillary tangle assembly (GO:1902997) 1 0 .00 - < 0.01 1.00E00 1.00E00 sensory perception of sound (GO:0007605) 167 0 .05 - < 0.01 1.00E00 1.00E00 regulation of neurofibrillary tangle assembly (GO:1902996) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling (GO:0060665) 4 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in salivary gland morphogenesis (GO:0060664) 5 0 .00 - < 0.01 1.00E00 1.00E00 phototransduction, UV (GO:0007604) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid efflux (GO:1902995) 4 0 .00 - < 0.01 1.00E00 1.00E00 phototransduction, visible light (GO:0007603) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipid efflux (GO:1902994) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amyloid precursor protein catabolic process (GO:1902993) 27 0 .01 - < 0.01 1.00E00 1.00E00 salivary gland cavitation (GO:0060662) 5 0 .00 - < 0.01 1.00E00 1.00E00 phototransduction (GO:0007602) 42 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of amyloid precursor protein catabolic process (GO:1902992) 19 0 .01 - < 0.01 1.00E00 1.00E00 visual perception (GO:0007601) 222 0 .06 - < 0.01 1.00E00 1.00E00 submandibular salivary gland formation (GO:0060661) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amyloid precursor protein catabolic process (GO:1902991) 44 0 .01 - < 0.01 1.00E00 1.00E00 sensory perception (GO:0007600) 998 0 .29 - < 0.01 1.00E00 1.00E00 mitotic telomere maintenance via semi-conservative replication (GO:1902990) 3 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue growth involved in heart morphogenesis (GO:0003245) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac chamber ballooning (GO:0003242) 1 0 .00 - < 0.01 1.00E00 1.00E00 growth involved in heart morphogenesis (GO:0003241) 4 0 .00 - < 0.01 1.00E00 1.00E00 deoxyribose phosphate catabolic process (GO:0046386) 28 0 .01 - < 0.01 1.00E00 1.00E00 deoxyribose phosphate biosynthetic process (GO:0046385) 15 0 .00 - < 0.01 1.00E00 1.00E00 CMP-N-acetylneuraminate metabolic process (GO:0046381) 6 0 .00 - < 0.01 1.00E00 1.00E00 N-acetylneuraminate biosynthetic process (GO:0046380) 3 0 .00 - < 0.01 1.00E00 1.00E00 nipple morphogenesis (GO:0060658) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurofibrillary tangle assembly (GO:1902988) 2 0 .00 - < 0.01 1.00E00 1.00E00 DNA strand elongation involved in mitotic DNA replication (GO:1902983) 1 0 .00 - < 0.01 1.00E00 1.00E00 sinus venosus morphogenesis (GO:0003236) 1 0 .00 - < 0.01 1.00E00 1.00E00 sinus venosus development (GO:0003235) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac ventricle development (GO:0003231) 128 0 .04 - < 0.01 1.00E00 1.00E00 cardiac atrium development (GO:0003230) 37 0 .01 - < 0.01 1.00E00 1.00E00 L-arabinose metabolic process (GO:0046373) 2 0 .00 - < 0.01 1.00E00 1.00E00 fructose biosynthetic process (GO:0046370) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication termination (GO:1902979) 1 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland bud morphogenesis (GO:0060648) 3 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication preinitiation complex assembly (GO:1902977) 1 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication initiation (GO:1902975) 5 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland epithelial cell differentiation (GO:0060644) 17 0 .00 - < 0.01 1.00E00 1.00E00 ventricular cardiac muscle tissue development (GO:0003229) 63 0 .02 - < 0.01 1.00E00 1.00E00 atrial cardiac muscle tissue development (GO:0003228) 22 0 .01 - < 0.01 1.00E00 1.00E00 right ventricular compact myocardium morphogenesis (GO:0003226) 1 0 .00 - < 0.01 1.00E00 1.00E00 ventricular compact myocardium morphogenesis (GO:0003223) 8 0 .00 - < 0.01 1.00E00 1.00E00 ventricular trabecula myocardium morphogenesis (GO:0003222) 14 0 .00 - < 0.01 1.00E00 1.00E00 right ventricular cardiac muscle tissue morphogenesis (GO:0003221) 3 0 .00 - < 0.01 1.00E00 1.00E00 GDP-L-fucose metabolic process (GO:0046368) 6 0 .00 - < 0.01 1.00E00 1.00E00 left ventricular cardiac muscle tissue morphogenesis (GO:0003220) 4 0 .00 - < 0.01 1.00E00 1.00E00 monosaccharide catabolic process (GO:0046365) 53 1 .02 + 64.72 1.54E-02 1.00E00 monosaccharide biosynthetic process (GO:0046364) 51 0 .01 - < 0.01 1.00E00 1.00E00 2-oxobutyrate metabolic process (GO:0046361) 2 0 .00 - < 0.01 1.00E00 1.00E00 2-oxobutyrate biosynthetic process (GO:0046360) 1 0 .00 - < 0.01 1.00E00 1.00E00 telomere tethering at nuclear periphery (GO:0034398) 6 0 .00 - < 0.01 1.00E00 1.00E00 telomere localization (GO:0034397) 12 0 .00 - < 0.01 1.00E00 1.00E00 mitotic DNA replication (GO:1902969) 14 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to cell surface (GO:0034394) 31 0 .01 - < 0.01 1.00E00 1.00E00 mesenchymal-epithelial cell signaling (GO:0060638) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of smooth muscle cell apoptotic process (GO:0034393) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of smooth muscle cell apoptotic process (GO:0034392) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein localization to early endosome (GO:1902966) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of smooth muscle cell apoptotic process (GO:0034391) 30 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein localization to early endosome (GO:1902965) 10 0 .00 - < 0.01 1.00E00 1.00E00 smooth muscle cell apoptotic process (GO:0034390) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription initiation by RNA polymerase II (GO:0060633) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of microtubule-based movement (GO:0060632) 62 0 .02 - < 0.01 1.00E00 1.00E00 regulation of meiosis I (GO:0060631) 6 0 .00 - < 0.01 1.00E00 1.00E00 cardiac right ventricle formation (GO:0003219) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process (GO:1902960) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac left ventricle formation (GO:0003218) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac right ventricle morphogenesis (GO:0003215) 19 0 .01 - < 0.01 1.00E00 1.00E00 cardiac left ventricle morphogenesis (GO:0003214) 17 0 .00 - < 0.01 1.00E00 1.00E00 cardiac right atrium morphogenesis (GO:0003213) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac ventricle formation (GO:0003211) 8 0 .00 - < 0.01 1.00E00 1.00E00 butyrate catabolic process (GO:0046359) 1 0 .00 - < 0.01 1.00E00 1.00E00 cardiac atrium formation (GO:0003210) 2 0 .00 - < 0.01 1.00E00 1.00E00 acetyl-CoA catabolic process (GO:0046356) 3 0 .00 - < 0.01 1.00E00 1.00E00 disaccharide catabolic process (GO:0046352) 4 0 .00 - < 0.01 1.00E00 1.00E00 disaccharide biosynthetic process (GO:0046351) 2 0 .00 - < 0.01 1.00E00 1.00E00 lipid droplet organization (GO:0034389) 38 0 .01 - < 0.01 1.00E00 1.00E00 regulation of homologous chromosome segregation (GO:0060629) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of ER to Golgi vesicle-mediated transport (GO:0060628) 10 0 .00 - < 0.01 1.00E00 1.00E00 high-density lipoprotein particle clearance (GO:0034384) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vesicle-mediated transport (GO:0060627) 543 0 .16 - < 0.01 1.00E00 1.00E00 low-density lipoprotein particle clearance (GO:0034383) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902958) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902957) 2 0 .00 - < 0.01 1.00E00 1.00E00 chylomicron remnant clearance (GO:0034382) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitochondrial electron transport, NADH to ubiquinone (GO:1902956) 5 0 .00 - < 0.01 1.00E00 1.00E00 plasma lipoprotein particle clearance (GO:0034381) 24 0 .01 - < 0.01 1.00E00 1.00E00 high-density lipoprotein particle assembly (GO:0034380) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of early endosome to recycling endosome transport (GO:1902955) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of chromosome condensation (GO:0060623) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of early endosome to recycling endosome transport (GO:1902954) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of ER to Golgi vesicle-mediated transport (GO:1902953) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cholesterol import (GO:0060621) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic spine maintenance (GO:1902952) 5 0 .00 - < 0.01 1.00E00 1.00E00 cardiac atrium morphogenesis (GO:0003209) 28 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cholesterol import (GO:0060620) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic spine maintenance (GO:1902951) 4 0 .00 - < 0.01 1.00E00 1.00E00 cardiac ventricle morphogenesis (GO:0003208) 71 0 .02 - < 0.01 1.00E00 1.00E00 regulation of dendritic spine maintenance (GO:1902950) 13 0 .00 - < 0.01 1.00E00 1.00E00 cardiac chamber formation (GO:0003207) 11 0 .00 - < 0.01 1.00E00 1.00E00 cardiac chamber morphogenesis (GO:0003206) 128 0 .04 - < 0.01 1.00E00 1.00E00 cardiac chamber development (GO:0003205) 171 0 .05 - < 0.01 1.00E00 1.00E00 endocardial cushion morphogenesis (GO:0003203) 40 0 .01 - < 0.01 1.00E00 1.00E00 amino sugar biosynthetic process (GO:0046349) 13 0 .00 - < 0.01 1.00E00 1.00E00 amino sugar catabolic process (GO:0046348) 14 0 .00 - < 0.01 1.00E00 1.00E00 CDP-diacylglycerol metabolic process (GO:0046341) 13 0 .00 - < 0.01 1.00E00 1.00E00 diacylglycerol catabolic process (GO:0046340) 6 0 .00 - < 0.01 1.00E00 1.00E00 very-low-density lipoprotein particle assembly (GO:0034379) 12 0 .00 - < 0.01 1.00E00 1.00E00 chylomicron assembly (GO:0034378) 4 0 .00 - < 0.01 1.00E00 1.00E00 craniofacial suture morphogenesis (GO:0097094) 19 0 .01 - < 0.01 1.00E00 1.00E00 plasma lipoprotein particle assembly (GO:0034377) 24 0 .01 - < 0.01 1.00E00 1.00E00 high-density lipoprotein particle remodeling (GO:0034375) 21 0 .01 - < 0.01 1.00E00 1.00E00 synaptic vesicle clustering (GO:0097091) 12 0 .00 - < 0.01 1.00E00 1.00E00 nipple development (GO:0060618) 1 0 .00 - < 0.01 1.00E00 1.00E00 low-density lipoprotein particle remodeling (GO:0034374) 16 0 .00 - < 0.01 1.00E00 1.00E00 presynaptic membrane organization (GO:0097090) 10 0 .00 - < 0.01 1.00E00 1.00E00 intermediate-density lipoprotein particle remodeling (GO:0034373) 1 0 .00 - < 0.01 1.00E00 1.00E00 very-low-density lipoprotein particle remodeling (GO:0034372) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to early endosome (GO:1902946) 2 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland bud formation (GO:0060615) 2 0 .00 - < 0.01 1.00E00 1.00E00 chylomicron remodeling (GO:0034371) 3 0 .00 - < 0.01 1.00E00 1.00E00 triglyceride-rich lipoprotein particle remodeling (GO:0034370) 9 0 .00 - < 0.01 1.00E00 1.00E00 fat pad development (GO:0060613) 9 0 .00 - < 0.01 1.00E00 1.00E00 adipose tissue development (GO:0060612) 45 1 .01 + 76.22 1.30E-02 1.00E00 positive regulation of voltage-gated chloride channel activity (GO:1902943) 1 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland fat development (GO:0060611) 1 0 .00 - < 0.01 1.00E00 1.00E00 diacylglycerol metabolic process (GO:0046339) 25 0 .01 - < 0.01 1.00E00 1.00E00 phosphatidylethanolamine catabolic process (GO:0046338) 4 0 .00 - < 0.01 1.00E00 1.00E00 phosphatidylethanolamine metabolic process (GO:0046337) 27 0 .01 - < 0.01 1.00E00 1.00E00 octopamine metabolic process (GO:0046333) 3 0 .00 - < 0.01 1.00E00 1.00E00 methyl-branched fatty acid metabolic process (GO:0097089) 4 0 .00 - < 0.01 1.00E00 1.00E00 lateral inhibition (GO:0046331) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of JNK cascade (GO:0046330) 97 0 .03 - < 0.01 1.00E00 1.00E00 plasma lipoprotein particle remodeling (GO:0034369) 36 0 .01 - < 0.01 1.00E00 1.00E00 protein-lipid complex remodeling (GO:0034368) 36 0 .01 - < 0.01 1.00E00 1.00E00 vascular associated smooth muscle cell development (GO:0097084) 12 0 .00 - < 0.01 1.00E00 1.00E00 protein-containing complex remodeling (GO:0034367) 38 0 .01 - < 0.01 1.00E00 1.00E00 plasma membrane selenite transport (GO:0097080) 1 0 .00 - < 0.01 1.00E00 1.00E00 tube closure (GO:0060606) 87 0 .03 - < 0.01 1.00E00 1.00E00 tube lumen cavitation (GO:0060605) 5 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland duct morphogenesis (GO:0060603) 31 0 .01 - < 0.01 1.00E00 1.00E00 branch elongation of an epithelium (GO:0060602) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of alcohol biosynthetic process (GO:1902932) 31 0 .01 - < 0.01 1.00E00 1.00E00 lateral sprouting from an epithelium (GO:0060601) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of alcohol biosynthetic process (GO:1902931) 15 0 .00 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of an epithelial terminal unit (GO:0060600) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of alcohol biosynthetic process (GO:1902930) 54 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of JNK cascade (GO:0046329) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of JNK cascade (GO:0046328) 141 0 .04 - < 0.01 1.00E00 1.00E00 glycerol biosynthetic process from pyruvate (GO:0046327) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of D-glucose import (GO:0046326) 36 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of D-glucose import (GO:0046325) 13 0 .00 - < 0.01 1.00E00 1.00E00 regulation of D-glucose import (GO:0046324) 56 0 .02 - < 0.01 1.00E00 1.00E00 D-glucose import (GO:0046323) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of fatty acid oxidation (GO:0046322) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fatty acid oxidation (GO:0046321) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fatty acid oxidation (GO:0046320) 35 0 .01 - < 0.01 1.00E00 1.00E00 NAD biosynthesis via nicotinamide riboside salvage pathway (GO:0034356) 10 0 .00 - < 0.01 1.00E00 1.00E00 NAD biosynthetic process via the salvage pathway (GO:0034355) 11 0 .00 - < 0.01 1.00E00 1.00E00 'de novo' NAD biosynthetic process from L-tryptophan (GO:0034354) 6 0 .00 - < 0.01 1.00E00 1.00E00 ductus arteriosus closure (GO:0097070) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glial cell apoptotic process (GO:0034352) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glial cell apoptotic process (GO:0034351) 10 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glial cell apoptotic process (GO:0034350) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glucosylceramide biosynthetic process (GO:0046318) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of glucosylceramide biosynthetic process (GO:0046317) 1 0 .00 - < 0.01 1.00E00 1.00E00 phosphocreatine biosynthetic process (GO:0046314) 4 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to thyroxine stimulus (GO:0097069) 2 0 .00 - < 0.01 1.00E00 1.00E00 response to thyroxine (GO:0097068) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to thyroid hormone stimulus (GO:0097067) 12 0 .00 - < 0.01 1.00E00 1.00E00 response to thyroid hormone (GO:0097066) 24 0 .01 - < 0.01 1.00E00 1.00E00 glial cell apoptotic process (GO:0034349) 5 0 .00 - < 0.01 1.00E00 1.00E00 anterior head development (GO:0097065) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of type III interferon production (GO:0034346) 2 0 .00 - < 0.01 1.00E00 1.00E00 dendritic spine maintenance (GO:0097062) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of type III interferon production (GO:0034345) 1 0 .00 - < 0.01 1.00E00 1.00E00 dendritic spine organization (GO:0097061) 33 0 .01 - < 0.01 1.00E00 1.00E00 regulation of type III interferon production (GO:0034344) 5 0 .00 - < 0.01 1.00E00 1.00E00 type III interferon production (GO:0034343) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to type III interferon (GO:0034342) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein polyubiquitination (GO:1902916) 18 0 .01 - < 0.01 1.00E00 1.00E00 response to type II interferon (GO:0034341) 108 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein polyubiquitination (GO:1902915) 7 0 .00 - < 0.01 1.00E00 1.00E00 response to type I interferon (GO:0034340) 57 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein polyubiquitination (GO:1902914) 28 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of neuroepithelial cell differentiation (GO:1902913) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of melanosome transport (GO:1902910) 1 0 .00 - < 0.01 1.00E00 1.00E00 alkanesulfonate biosynthetic process (GO:0046305) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of peptide secretion (GO:0002793) 116 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of peptide secretion (GO:0002792) 48 0 .01 - < 0.01 1.00E00 1.00E00 regulation of peptide secretion (GO:0002791) 209 0 .06 - < 0.01 1.00E00 1.00E00 peptide secretion (GO:0002790) 78 0 .02 - < 0.01 1.00E00 1.00E00 agmatine biosynthetic process (GO:0097055) 2 0 .00 - < 0.01 1.00E00 1.00E00 RNA folding (GO:0034337) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-kynurenine catabolic process (GO:0097053) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-kynurenine metabolic process (GO:0097052) 5 0 .00 - < 0.01 1.00E00 1.00E00 adherens junction maintenance (GO:0034334) 7 0 .00 - < 0.01 1.00E00 1.00E00 retrograde axonal transport (GO:0008090) 21 0 .01 - < 0.01 1.00E00 1.00E00 establishment of protein localization to endoplasmic reticulum membrane (GO:0097051) 3 0 .00 - < 0.01 1.00E00 1.00E00 type B pancreatic cell apoptotic process (GO:0097050) 3 0 .00 - < 0.01 1.00E00 1.00E00 adherens junction assembly (GO:0034333) 15 0 .00 - < 0.01 1.00E00 1.00E00 regulation of melanosome transport (GO:1902908) 2 0 .00 - < 0.01 1.00E00 1.00E00 adherens junction organization (GO:0034332) 54 0 .02 - < 0.01 1.00E00 1.00E00 cell junction maintenance (GO:0034331) 51 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of supramolecular fiber organization (GO:1902905) 176 0 .05 - < 0.01 1.00E00 1.00E00 cell junction organization (GO:0034330) 564 0 .16 - < 0.01 1.00E00 1.00E00 negative regulation of supramolecular fiber organization (GO:1902904) 157 0 .05 - < 0.01 1.00E00 1.00E00 regulation of supramolecular fiber organization (GO:1902903) 393 0 .11 - < 0.01 1.00E00 1.00E00 negative regulation of autophagosome assembly (GO:1902902) 13 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antibacterial peptide production (GO:0002787) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antibacterial peptide production (GO:0002786) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of antimicrobial peptide production (GO:0002785) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial peptide production (GO:0002784) 9 0 .00 - < 0.01 1.00E00 1.00E00 anterograde axonal transport (GO:0008089) 45 0 .01 - < 0.01 1.00E00 1.00E00 motor neuron apoptotic process (GO:0097049) 15 0 .00 - < 0.01 1.00E00 1.00E00 axo-dendritic transport (GO:0008088) 78 0 .02 - < 0.01 1.00E00 1.00E00 dendritic cell apoptotic process (GO:0097048) 2 0 .00 - < 0.01 1.00E00 1.00E00 antibacterial peptide biosynthetic process (GO:0002780) 4 0 .00 - < 0.01 1.00E00 1.00E00 cell junction assembly (GO:0034329) 303 0 .09 - < 0.01 1.00E00 1.00E00 phosphatidylserine exposure on blood platelet (GO:0097045) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of muscle adaptation (GO:0014745) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of muscle adaptation (GO:0014744) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle hypertrophy (GO:0014743) 62 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of muscle hypertrophy (GO:0014742) 30 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of muscle hypertrophy (GO:0014741) 32 0 .01 - < 0.01 1.00E00 1.00E00 regulation of G2/M transition of mitotic cell cycle (GO:0010389) 106 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of muscle hyperplasia (GO:0014740) 1 0 .00 - < 0.01 1.00E00 1.00E00 antibacterial peptide secretion (GO:0002779) 1 0 .00 - < 0.01 1.00E00 1.00E00 COP9 signalosome assembly (GO:0010387) 5 0 .00 - < 0.01 1.00E00 1.00E00 antibacterial peptide production (GO:0002778) 4 0 .00 - < 0.01 1.00E00 1.00E00 antimicrobial peptide biosynthetic process (GO:0002777) 4 0 .00 - < 0.01 1.00E00 1.00E00 antimicrobial peptide secretion (GO:0002776) 1 0 .00 - < 0.01 1.00E00 1.00E00 antimicrobial peptide production (GO:0002775) 4 0 .00 - < 0.01 1.00E00 1.00E00 Fc receptor mediated inhibitory signaling pathway (GO:0002774) 5 0 .00 - < 0.01 1.00E00 1.00E00 mesodermal cell migration (GO:0008078) 5 0 .00 - < 0.01 1.00E00 1.00E00 protein linear polyubiquitination (GO:0097039) 3 0 .00 - < 0.01 1.00E00 1.00E00 heme export (GO:0097037) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasma membrane sterol distribution (GO:0097036) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of membrane lipid distribution (GO:0097035) 65 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of Arp2/3 complex-mediated actin nucleation (GO:0034316) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Arp2/3 complex-mediated actin nucleation (GO:0034315) 33 0 .01 - < 0.01 1.00E00 1.00E00 Arp2/3 complex-mediated actin nucleation (GO:0034314) 20 0 .01 - < 0.01 1.00E00 1.00E00 diol biosynthetic process (GO:0034312) 22 0 .01 - < 0.01 1.00E00 1.00E00 diol metabolic process (GO:0034311) 32 0 .01 - < 0.01 1.00E00 1.00E00 primary alcohol catabolic process (GO:0034310) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle hyperplasia (GO:0014738) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of muscle atrophy (GO:0014737) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of muscle atrophy (GO:0014736) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of muscle atrophy (GO:0014735) 3 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle hypertrophy (GO:0014734) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle adaptation (GO:0014733) 12 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle atrophy (GO:0014732) 6 0 .00 - < 0.01 1.00E00 1.00E00 natural killer cell inhibitory signaling pathway (GO:0002769) 3 0 .00 - < 0.01 1.00E00 1.00E00 immune response-regulating cell surface receptor signaling pathway (GO:0002768) 285 0 .08 - < 0.01 1.00E00 1.00E00 immune response-inhibiting cell surface receptor signaling pathway (GO:0002767) 9 0 .00 - < 0.01 1.00E00 1.00E00 immune response-inhibiting signal transduction (GO:0002765) 11 0 .00 - < 0.01 1.00E00 1.00E00 immune response-regulating signaling pathway (GO:0002764) 403 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid leukocyte differentiation (GO:0002763) 63 0 .02 - < 0.01 1.00E00 1.00E00 mature conventional dendritic cell differentiation (GO:0097029) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of myeloid leukocyte differentiation (GO:0002762) 55 0 .02 - < 0.01 1.00E00 1.00E00 dendritic cell differentiation (GO:0097028) 37 0 .01 - < 0.01 1.00E00 1.00E00 regulation of myeloid leukocyte differentiation (GO:0002761) 127 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of antimicrobial humoral response (GO:0002760) 8 0 .00 - < 0.01 1.00E00 1.00E00 dendritic cell dendrite assembly (GO:0097026) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of blood-nerve barrier (GO:0008065) 3 0 .00 - < 0.01 1.00E00 1.00E00 primary alcohol biosynthetic process (GO:0034309) 4 0 .00 - < 0.01 1.00E00 1.00E00 primary alcohol metabolic process (GO:0034308) 92 1 .03 + 37.28 2.65E-02 1.00E00 regulation of actin polymerization or depolymerization (GO:0008064) 147 0 .04 - < 0.01 1.00E00 1.00E00 Toll signaling pathway (GO:0008063) 7 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte migration into lymph node (GO:0097022) 4 0 .00 - < 0.01 1.00E00 1.00E00 lymphocyte migration into lymphoid organs (GO:0097021) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of the force of skeletal muscle contraction (GO:0014728) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of twitch skeletal muscle contraction (GO:0014724) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril (GO:0014723) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle contraction by calcium ion signaling (GO:0014722) 8 0 .00 - < 0.01 1.00E00 1.00E00 twitch skeletal muscle contraction (GO:0014721) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of antimicrobial humoral response (GO:0002759) 12 0 .00 - < 0.01 1.00E00 1.00E00 innate immune response-activating signaling pathway (GO:0002758) 150 0 .04 - < 0.01 1.00E00 1.00E00 immune response-activating signaling pathway (GO:0002757) 333 0 .10 - < 0.01 1.00E00 1.00E00 MyD88-independent toll-like receptor signaling pathway (GO:0002756) 14 0 .00 - < 0.01 1.00E00 1.00E00 MyD88-dependent toll-like receptor signaling pathway (GO:0002755) 16 0 .00 - < 0.01 1.00E00 1.00E00 cytoplasmic pattern recognition receptor signaling pathway (GO:0002753) 75 0 .02 - < 0.01 1.00E00 1.00E00 cell surface pattern recognition receptor signaling pathway (GO:0002752) 46 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0045899) 4 0 .00 - < 0.01 1.00E00 1.00E00 eye pigment granule organization (GO:0008057) 1 0 .00 - < 0.01 1.00E00 1.00E00 renal albumin absorption (GO:0097018) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of anion channel activity (GO:0010360) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of RNA polymerase II transcription preinitiation complex assembly (GO:0045898) 6 0 .00 - < 0.01 1.00E00 1.00E00 renal protein absorption (GO:0097017) 8 0 .00 - < 0.01 1.00E00 1.00E00 mitochondrial fusion (GO:0008053) 21 0 .01 - < 0.01 1.00E00 1.00E00 sensory organ boundary specification (GO:0008052) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to granulocyte macrophage colony-stimulating factor (GO:0097012) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of DNA-templated transcription (GO:0045893) 1667 0 .49 - < 0.01 1.00E00 1.00E00 cellular response to granulocyte macrophage colony-stimulating factor stimulus (GO:0097011) 11 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of DNA-templated transcription (GO:0045892) 1277 0 .37 - < 0.01 1.00E00 1.00E00 female courtship behavior (GO:0008050) 2 0 .00 - < 0.01 1.00E00 1.00E00 eukaryotic translation initiation factor 4F complex assembly (GO:0097010) 2 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle satellite cell activation (GO:0014719) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014718) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of satellite cell activation involved in skeletal muscle regeneration (GO:0014717) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of anion channel activity (GO:0010359) 4 0 .00 - < 0.01 1.00E00 1.00E00 antigen processing and presentation following phagocytosis (GO:0002747) 1 0 .00 - < 0.01 1.00E00 1.00E00 male courtship behavior (GO:0008049) 1 0 .00 - < 0.01 1.00E00 1.00E00 energy homeostasis (GO:0097009) 85 0 .02 - < 0.01 1.00E00 1.00E00 lithium ion transport (GO:0010351) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasma lipoprotein particle levels (GO:0097006) 63 0 .02 - < 0.01 1.00E00 1.00E00 motor neuron axon guidance (GO:0008045) 26 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic assembly at neuromuscular junction (GO:0045887) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of smoothened signaling pathway (GO:0045880) 37 0 .01 - < 0.01 1.00E00 1.00E00 branchiomeric skeletal muscle development (GO:0014707) 3 0 .00 - < 0.01 1.00E00 1.00E00 striated muscle tissue development (GO:0014706) 330 1 .10 + 10.39 9.24E-02 1.00E00 negative regulation of plasmacytoid dendritic cell cytokine production (GO:0002737) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of plasmacytoid dendritic cell cytokine production (GO:0002736) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid dendritic cell cytokine production (GO:0002735) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein tyrosine kinase activity (GO:0061099) 15 0 .00 - < 0.01 1.00E00 1.00E00 synaptic target recognition (GO:0008039) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of myeloid dendritic cell cytokine production (GO:0002733) 6 0 .00 - < 0.01 1.00E00 1.00E00 neuron recognition (GO:0008038) 48 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of protein tyrosine kinase activity (GO:0061098) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic cell cytokine production (GO:0002732) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein tyrosine kinase activity (GO:0061097) 30 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of smoothened signaling pathway (GO:0045879) 35 0 .01 - < 0.01 1.00E00 1.00E00 cell recognition (GO:0008037) 140 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic cell cytokine production (GO:0002731) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic cell cytokine production (GO:0002730) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of sister chromatid cohesion (GO:0045876) 9 0 .00 - < 0.01 1.00E00 1.00E00 tRNA processing (GO:0008033) 133 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of sister chromatid cohesion (GO:0045875) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of phospholipid translocation (GO:0061092) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of phospholipid translocation (GO:0061091) 6 0 .00 - < 0.01 1.00E00 1.00E00 extracellular matrix assembly (GO:0085029) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045870) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein K6-linked ubiquitination (GO:0085020) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell cytokine production (GO:0002729) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell cytokine production (GO:0002728) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell cytokine production (GO:0002727) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of T cell cytokine production (GO:0002726) 28 0 .01 - < 0.01 1.00E00 1.00E00 response to non-ionic osmotic stress (GO:0010335) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of T cell cytokine production (GO:0002725) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell cytokine production (GO:0002724) 40 0 .01 - < 0.01 1.00E00 1.00E00 response to gamma radiation (GO:0010332) 53 0 .02 - < 0.01 1.00E00 1.00E00 regulation of B cell cytokine production (GO:0002721) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045869) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cytokine production involved in immune response (GO:0002720) 85 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of protein refolding (GO:0061084) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein refolding (GO:0061083) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081) 35 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of proteolysis (GO:0045862) 211 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of proteolysis (GO:0045861) 140 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of protein kinase activity (GO:0045860) 186 0 .05 - < 0.01 1.00E00 1.00E00 entry into host cell by a symbiont-containing vacuole (GO:0085017) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cytokine production involved in immune response (GO:0002719) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of cytokine production involved in immune response (GO:0002718) 125 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of natural killer cell mediated immunity (GO:0002717) 34 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of natural killer cell mediated immunity (GO:0002716) 27 0 .01 - < 0.01 1.00E00 1.00E00 membrane invagination (GO:0010324) 49 0 .01 - < 0.01 1.00E00 1.00E00 regulation of natural killer cell mediated immunity (GO:0002715) 58 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of B cell mediated immunity (GO:0002714) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of B cell mediated immunity (GO:0002713) 14 0 .00 - < 0.01 1.00E00 1.00E00 regulation of B cell mediated immunity (GO:0002712) 62 0 .02 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin secretion involved in immune response (GO:0061078) 1 0 .00 - < 0.01 1.00E00 1.00E00 chaperone-mediated protein folding (GO:0061077) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of protein kinase activity (GO:0045859) 327 0 .10 - < 0.01 1.00E00 1.00E00 positive regulation of T cell mediated immunity (GO:0002711) 72 0 .02 - < 0.01 1.00E00 1.00E00 regulation of heart contraction (GO:0008016) 202 0 .06 - < 0.01 1.00E00 1.00E00 negative regulation of T cell mediated immunity (GO:0002710) 32 0 .01 - < 0.01 1.00E00 1.00E00 blood circulation (GO:0008015) 429 0 .13 - < 0.01 1.00E00 1.00E00 regulation of neural retina development (GO:0061074) 3 0 .00 - < 0.01 1.00E00 1.00E00 ciliary body morphogenesis (GO:0061073) 4 0 .00 - < 0.01 1.00E00 1.00E00 iris morphogenesis (GO:0061072) 9 0 .00 - < 0.01 1.00E00 1.00E00 pH elevation (GO:0045852) 1 0 .00 - < 0.01 1.00E00 1.00E00 pH reduction (GO:0045851) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of T cell mediated immunity (GO:0002709) 106 0 .03 - < 0.01 1.00E00 1.00E00 positive regulation of lymphocyte mediated immunity (GO:0002708) 132 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of lymphocyte mediated immunity (GO:0002707) 65 0 .02 - < 0.01 1.00E00 1.00E00 regulation of lymphocyte mediated immunity (GO:0002706) 199 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte mediated immunity (GO:0002705) 154 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte mediated immunity (GO:0002704) 76 0 .02 - < 0.01 1.00E00 1.00E00 regulation of leukocyte mediated immunity (GO:0002703) 259 0 .08 - < 0.01 1.00E00 1.00E00 detoxification of zinc ion (GO:0010312) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of production of molecular mediator of immune response (GO:0002702) 142 0 .04 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide metabolic process (GO:0010310) 18 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of production of molecular mediator of immune response (GO:0002701) 45 0 .01 - < 0.01 1.00E00 1.00E00 regulation of production of molecular mediator of immune response (GO:0002700) 197 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of nitrogen utilization (GO:0045848) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to kinetochore involved in kinetochore assembly (GO:1903394) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of striated muscle tissue development (GO:0045844) 24 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of adherens junction organization (GO:1903393) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of adherens junction organization (GO:1903392) 3 0 .00 - < 0.01 1.00E00 1.00E00 muscle structure development (GO:0061061) 520 1 .15 + 6.60 1.42E-01 1.00E00 negative regulation of striated muscle tissue development (GO:0045843) 11 0 .00 - < 0.01 1.00E00 1.00E00 regulation of adherens junction organization (GO:1903391) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic metaphase/anaphase transition (GO:0045842) 17 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic metaphase/anaphase transition (GO:0045841) 33 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic nuclear division (GO:0045840) 47 0 .01 - < 0.01 1.00E00 1.00E00 ribonucleoside bisphosphate metabolic process (GO:0033875) 16 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of mitotic nuclear division (GO:0045839) 41 0 .01 - < 0.01 1.00E00 1.00E00 sclerotome development (GO:0061056) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of membrane potential (GO:0045838) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of homophilic cell adhesion (GO:1903387) 1 0 .00 - < 0.01 1.00E00 1.00E00 myotome development (GO:0061055) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of membrane potential (GO:0045837) 13 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of meiotic nuclear division (GO:0045836) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of homophilic cell adhesion (GO:1903385) 3 0 .00 - < 0.01 1.00E00 1.00E00 somite development (GO:0061053) 77 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of meiotic nuclear division (GO:0045835) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway (GO:1903384) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell growth involved in cardiac muscle cell development (GO:0061052) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of lipid metabolic process (GO:0045834) 131 0 .04 - < 0.01 1.00E00 1.00E00 regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway (GO:1903383) 3 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of lipid metabolic process (GO:0045833) 103 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903382) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell growth involved in cardiac muscle cell development (GO:0061051) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell growth involved in cardiac muscle cell development (GO:0061050) 16 0 .00 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903381) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of isotype switching (GO:0045830) 29 0 .01 - < 0.01 1.00E00 1.00E00 nucleoside bisphosphate biosynthetic process (GO:0033866) 2 0 .00 - < 0.01 1.00E00 1.00E00 nucleoside bisphosphate metabolic process (GO:0033865) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of NAD(P)H oxidase activity (GO:0033864) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of NAD(P)H oxidase activity (GO:0033861) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of NAD(P)H oxidase activity (GO:0033860) 4 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment (GO:0021899) 1 0 .00 - < 0.01 1.00E00 1.00E00 commitment of multipotent stem cells to neuronal lineage in forebrain (GO:0021898) 1 0 .00 - < 0.01 1.00E00 1.00E00 forebrain astrocyte development (GO:0021897) 3 0 .00 - < 0.01 1.00E00 1.00E00 forebrain astrocyte differentiation (GO:0021896) 3 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex neuron differentiation (GO:0021895) 27 0 .01 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron development (GO:0021894) 7 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron fate commitment (GO:0021893) 2 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron differentiation (GO:0021892) 11 0 .00 - < 0.01 1.00E00 1.00E00 olfactory bulb interneuron development (GO:0021891) 6 0 .00 - < 0.01 1.00E00 1.00E00 cell growth involved in cardiac muscle cell development (GO:0061049) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mitotic chromosome condensation (GO:1903379) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of branching involved in lung morphogenesis (GO:0061048) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of branching involved in lung morphogenesis (GO:0061047) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of isotype switching (GO:0045829) 4 0 .00 - < 0.01 1.00E00 1.00E00 glucuronate metabolic process (GO:0019585) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903378) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of branching involved in lung morphogenesis (GO:0061046) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903377) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of isoprenoid metabolic process (GO:0045828) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of wound healing (GO:0061045) 67 0 .02 - < 0.01 1.00E00 1.00E00 regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway (GO:1903376) 21 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of isoprenoid metabolic process (GO:0045827) 2 0 .00 - < 0.01 1.00E00 1.00E00 facioacoustic ganglion development (GO:1903375) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vascular wound healing (GO:0061044) 5 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vascular wound healing (GO:0061043) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of innate immune response (GO:0045824) 97 0 .03 - < 0.01 1.00E00 1.00E00 vascular wound healing (GO:0061042) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of endoplasmic reticulum tubular network organization (GO:1903373) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of wound healing (GO:0061041) 131 0 .04 - < 0.01 1.00E00 1.00E00 positive regulation of heart contraction (GO:0045823) 38 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of heart contraction (GO:0045822) 21 0 .01 - < 0.01 1.00E00 1.00E00 regulation of endoplasmic reticulum tubular network organization (GO:1903371) 6 0 .00 - < 0.01 1.00E00 1.00E00 female gonad morphogenesis (GO:0061040) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glycolytic process (GO:0045821) 25 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glycolytic process (GO:0045820) 19 0 .01 - < 0.01 1.00E00 1.00E00 olfactory bulb interneuron differentiation (GO:0021889) 11 0 .00 - < 0.01 1.00E00 1.00E00 hypothalamus gonadotrophin-releasing hormone neuron development (GO:0021888) 8 0 .00 - < 0.01 1.00E00 1.00E00 hypothalamus gonadotrophin-releasing hormone neuron differentiation (GO:0021886) 8 0 .00 - < 0.01 1.00E00 1.00E00 forebrain cell migration (GO:0021885) 65 0 .02 - < 0.01 1.00E00 1.00E00 forebrain neuron development (GO:0021884) 36 0 .01 - < 0.01 1.00E00 1.00E00 uterus morphogenesis (GO:0061038) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cartilage development (GO:0061037) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of glycogen catabolic process (GO:0045819) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fear response (GO:1903367) 8 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cartilage development (GO:0061036) 32 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of glycogen catabolic process (GO:0045818) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cartilage development (GO:0061035) 72 0 .02 - < 0.01 1.00E00 1.00E00 regulation of fear response (GO:1903365) 11 0 .00 - < 0.01 1.00E00 1.00E00 olfactory bulb mitral cell layer development (GO:0061034) 3 0 .00 - < 0.01 1.00E00 1.00E00 secretion by lung epithelial cell involved in lung growth (GO:0061033) 3 0 .00 - < 0.01 1.00E00 1.00E00 transcription initiation-coupled chromatin remodeling (GO:0045815) 53 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of gene expression, epigenetic (GO:0045814) 189 0 .06 - < 0.01 1.00E00 1.00E00 visceral serous pericardium development (GO:0061032) 2 0 .00 - < 0.01 1.00E00 1.00E00 endodermal digestive tract morphogenesis (GO:0061031) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of Wnt signaling pathway, calcium modulating pathway (GO:0045813) 1 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell differentiation involved in mammary gland alveolus development (GO:0061030) 4 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to basolateral plasma membrane (GO:1903361) 3 0 .00 - < 0.01 1.00E00 1.00E00 forebrain neuron differentiation (GO:0021879) 72 0 .02 - < 0.01 1.00E00 1.00E00 forebrain neuron fate commitment (GO:0021877) 8 0 .00 - < 0.01 1.00E00 1.00E00 Wnt signaling pathway involved in forebrain neuroblast division (GO:0021874) 1 0 .00 - < 0.01 1.00E00 1.00E00 forebrain neuroblast division (GO:0021873) 6 0 .00 - < 0.01 1.00E00 1.00E00 forebrain generation of neurons (GO:0021872) 82 0 .02 - < 0.01 1.00E00 1.00E00 forebrain regionalization (GO:0021871) 24 0 .01 - < 0.01 1.00E00 1.00E00 eyelid development in camera-type eye (GO:0061029) 13 0 .00 - < 0.01 1.00E00 1.00E00 Cajal-Retzius cell differentiation (GO:0021870) 2 0 .00 - < 0.01 1.00E00 1.00E00 establishment of endothelial barrier (GO:0061028) 33 0 .01 - < 0.01 1.00E00 1.00E00 arabinose metabolic process (GO:0019566) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of Golgi organization (GO:1903358) 15 0 .00 - < 0.01 1.00E00 1.00E00 umbilical cord development (GO:0061027) 2 0 .00 - < 0.01 1.00E00 1.00E00 cardiac muscle tissue regeneration (GO:0061026) 4 0 .00 - < 0.01 1.00E00 1.00E00 membrane fusion (GO:0061025) 164 0 .05 - < 0.01 1.00E00 1.00E00 positive regulation of endocytosis (GO:0045807) 159 0 .05 - < 0.01 1.00E00 1.00E00 glycerol catabolic process (GO:0019563) 7 0 .00 - < 0.01 1.00E00 1.00E00 membrane organization (GO:0061024) 763 0 .22 - < 0.01 1.00E00 1.00E00 negative regulation of endocytosis (GO:0045806) 68 0 .02 - < 0.01 1.00E00 1.00E00 regulation of nucleus organization (GO:1903353) 1 0 .00 - < 0.01 1.00E00 1.00E00 L-ornithine transmembrane transport (GO:1903352) 6 0 .00 - < 0.01 1.00E00 1.00E00 hemostasis (GO:0007599) 196 0 .06 - < 0.01 1.00E00 1.00E00 cellular response to dopamine (GO:1903351) 48 0 .01 - < 0.01 1.00E00 1.00E00 response to dopamine (GO:1903350) 50 0 .01 - < 0.01 1.00E00 1.00E00 blood coagulation, intrinsic pathway (GO:0007597) 8 0 .00 - < 0.01 1.00E00 1.00E00 blood coagulation (GO:0007596) 190 0 .06 - < 0.01 1.00E00 1.00E00 lactation (GO:0007595) 40 0 .01 - < 0.01 1.00E00 1.00E00 forebrain ventricular zone progenitor cell division (GO:0021869) 6 0 .00 - < 0.01 1.00E00 1.00E00 forebrain radial glial cell differentiation (GO:0021861) 7 0 .00 - < 0.01 1.00E00 1.00E00 pyramidal neuron development (GO:0021860) 11 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine catabolic process to glutamate and formate (GO:0019557) 4 0 .00 - < 0.01 1.00E00 1.00E00 L-histidine catabolic process to glutamate and formamide (GO:0019556) 4 0 .00 - < 0.01 1.00E00 1.00E00 hepatoblast differentiation (GO:0061017) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of bicellular tight junction assembly (GO:1903348) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of bicellular tight junction assembly (GO:1903347) 4 0 .00 - < 0.01 1.00E00 1.00E00 snRNA import into nucleus (GO:0061015) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA catabolic process (GO:0061014) 91 0 .03 - < 0.01 1.00E00 1.00E00 glutamate catabolic process via 2-hydroxyglutarate (GO:0019552) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of mRNA catabolic process (GO:0061013) 190 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of meiotic DNA double-strand break formation (GO:1903343) 1 0 .00 - < 0.01 1.00E00 1.00E00 glutamate catabolic process to aspartate (GO:0019550) 2 0 .00 - < 0.01 1.00E00 1.00E00 body fluid secretion (GO:0007589) 75 0 .02 - < 0.01 1.00E00 1.00E00 regulation of meiotic DNA double-strand break formation (GO:1903341) 1 0 .00 - < 0.01 1.00E00 1.00E00 excretion (GO:0007588) 19 0 .01 - < 0.01 1.00E00 1.00E00 gallbladder development (GO:0061010) 2 0 .00 - < 0.01 1.00E00 1.00E00 digestion (GO:0007586) 114 0 .03 - < 0.01 1.00E00 1.00E00 respiratory gaseous exchange by respiratory system (GO:0007585) 58 0 .02 - < 0.01 1.00E00 1.00E00 response to nutrient (GO:0007584) 159 0 .05 - < 0.01 1.00E00 1.00E00 pyramidal neuron differentiation (GO:0021859) 15 0 .00 - < 0.01 1.00E00 1.00E00 GABAergic neuron differentiation in basal ganglia (GO:0021858) 1 0 .00 - < 0.01 1.00E00 1.00E00 hypothalamic tangential migration using cell-axon interactions (GO:0021856) 6 0 .00 - < 0.01 1.00E00 1.00E00 hypothalamus cell migration (GO:0021855) 7 0 .00 - < 0.01 1.00E00 1.00E00 hypothalamus development (GO:0021854) 29 0 .01 - < 0.01 1.00E00 1.00E00 cerebral cortex GABAergic interneuron migration (GO:0021853) 6 0 .00 - < 0.01 1.00E00 1.00E00 pyramidal neuron migration to cerebral cortex (GO:0021852) 3 0 .00 - < 0.01 1.00E00 1.00E00 common bile duct development (GO:0061009) 5 0 .00 - < 0.01 1.00E00 1.00E00 arginine catabolic process to ornithine (GO:0019547) 2 0 .00 - < 0.01 1.00E00 1.00E00 hepaticobiliary system development (GO:0061008) 138 0 .04 - < 0.01 1.00E00 1.00E00 arginine catabolic process to glutamate (GO:0019544) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vacuolar transport (GO:1903337) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cell proliferation involved in kidney morphogenesis (GO:0061006) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell differentiation involved in kidney development (GO:0061005) 48 0 .01 - < 0.01 1.00E00 1.00E00 propionate catabolic process (GO:0019543) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of vacuolar transport (GO:1903336) 2 0 .00 - < 0.01 1.00E00 1.00E00 pattern specification involved in kidney development (GO:0061004) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vacuolar transport (GO:1903335) 3 0 .00 - < 0.01 1.00E00 1.00E00 propionate biosynthetic process (GO:0019542) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of dendritic spine morphogenesis (GO:0061003) 19 0 .01 - < 0.01 1.00E00 1.00E00 propionate metabolic process (GO:0019541) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein folding (GO:1903334) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic spine morphogenesis (GO:0061002) 6 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of protein folding (GO:1903333) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of dendritic spine morphogenesis (GO:0061001) 44 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein folding (GO:1903332) 8 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of dendritic spine development (GO:0061000) 14 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of iron-sulfur cluster assembly (GO:1903331) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuroblast division in subventricular zone (GO:0021849) 3 0 .00 - < 0.01 1.00E00 1.00E00 ventricular zone neuroblast division (GO:0021847) 3 0 .00 - < 0.01 1.00E00 1.00E00 cell proliferation in forebrain (GO:0021846) 27 0 .01 - < 0.01 1.00E00 1.00E00 substrate-independent telencephalic tangential interneuron migration (GO:0021843) 8 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to endoplasmic reticulum (GO:0072599) 40 0 .01 - < 0.01 1.00E00 1.00E00 chemorepulsion involved in interneuron migration from the subpallium to the cortex (GO:0021842) 1 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to chloroplast (GO:0072598) 3 0 .00 - < 0.01 1.00E00 1.00E00 protein metabolic process (GO:0019538) 3368 0 .98 - < 0.01 5.98E-01 1.00E00 directional guidance of interneurons involved in migration from the subpallium to the cortex (GO:0021840) 1 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to chloroplast (GO:0072596) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of iron-sulfur cluster assembly (GO:1903329) 1 0 .00 - < 0.01 1.00E00 1.00E00 maintenance of protein localization in organelle (GO:0072595) 44 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of tRNA metabolic process (GO:1903327) 4 0 .00 - < 0.01 1.00E00 1.00E00 establishment of protein localization to organelle (GO:0072594) 344 0 .10 - < 0.01 1.00E00 1.00E00 regulation of tRNA metabolic process (GO:1903326) 5 0 .00 - < 0.01 1.00E00 1.00E00 reactive oxygen species metabolic process (GO:0072593) 112 0 .03 - < 0.01 1.00E00 1.00E00 oxalate transport (GO:0019532) 12 0 .00 - < 0.01 1.00E00 1.00E00 oxygen metabolic process (GO:0072592) 5 0 .00 - < 0.01 1.00E00 1.00E00 taurine metabolic process (GO:0019530) 10 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein modification by small protein conjugation or removal (GO:1903322) 131 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of protein modification by small protein conjugation or removal (GO:1903321) 87 0 .03 - < 0.01 1.00E00 1.00E00 regulation of protein modification by small protein conjugation or removal (GO:1903320) 237 0 .07 - < 0.01 1.00E00 1.00E00 parturition (GO:0007567) 15 0 .00 - < 0.01 1.00E00 1.00E00 embryo implantation (GO:0007566) 48 0 .01 - < 0.01 1.00E00 1.00E00 female pregnancy (GO:0007565) 176 0 .05 - < 0.01 1.00E00 1.00E00 chemorepulsion involved in postnatal olfactory bulb interneuron migration (GO:0021836) 2 0 .00 - < 0.01 1.00E00 1.00E00 embryonic olfactory bulb interneuron precursor migration (GO:0021831) 1 0 .00 - < 0.01 1.00E00 1.00E00 interneuron migration from the subpallium to the cortex (GO:0021830) 8 0 .00 - < 0.01 1.00E00 1.00E00 pentitol catabolic process (GO:0019527) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of protein maturation (GO:1903319) 26 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of protein maturation (GO:1903318) 25 0 .01 - < 0.01 1.00E00 1.00E00 regulation of protein maturation (GO:1903317) 65 0 .02 - < 0.01 1.00E00 1.00E00 caveolin-mediated endocytosis (GO:0072584) 5 0 .00 - < 0.01 1.00E00 1.00E00 clathrin-dependent endocytosis (GO:0072583) 34 0 .01 - < 0.01 1.00E00 1.00E00 regulation of nitrogen cycle metabolic process (GO:1903314) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mRNA metabolic process (GO:1903313) 125 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of mRNA metabolic process (GO:1903312) 101 0 .03 - < 0.01 1.00E00 1.00E00 regulation of mRNA metabolic process (GO:1903311) 304 0 .09 - < 0.01 1.00E00 1.00E00 endocardial cushion to mesenchymal transition involved in heart valve formation (GO:0003199) 2 0 .00 - < 0.01 1.00E00 1.00E00 epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) 12 0 .00 - < 0.01 1.00E00 1.00E00 endocardial cushion development (GO:0003197) 51 0 .01 - < 0.01 1.00E00 1.00E00 tricuspid valve formation (GO:0003195) 2 0 .00 - < 0.01 1.00E00 1.00E00 gonadotrophin-releasing hormone neuronal migration to the hypothalamus (GO:0021828) 6 0 .00 - < 0.01 1.00E00 1.00E00 pulmonary valve formation (GO:0003193) 2 0 .00 - < 0.01 1.00E00 1.00E00 postnatal olfactory bulb interneuron migration (GO:0021827) 2 0 .00 - < 0.01 1.00E00 1.00E00 mitral valve formation (GO:0003192) 3 0 .00 - < 0.01 1.00E00 1.00E00 substrate-independent telencephalic tangential migration (GO:0021826) 8 0 .00 - < 0.01 1.00E00 1.00E00 substrate-dependent cerebral cortex tangential migration (GO:0021825) 2 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular valve formation (GO:0003190) 8 0 .00 - < 0.01 1.00E00 1.00E00 cerebral cortex tangential migration using cell-cell interactions (GO:0021823) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cell motility involved in cerebral cortex radial glia guided migration (GO:0021822) 1 0 .00 - < 0.01 1.00E00 1.00E00 pentitol metabolic process (GO:0019519) 2 0 .00 - < 0.01 1.00E00 1.00E00 glycine receptor clustering (GO:0072579) 1 0 .00 - < 0.01 1.00E00 1.00E00 neurotransmitter-gated ion channel clustering (GO:0072578) 13 0 .00 - < 0.01 1.00E00 1.00E00 L-threonine catabolic process to glycine (GO:0019518) 1 0 .00 - < 0.01 1.00E00 1.00E00 endothelial cell apoptotic process (GO:0072577) 11 0 .00 - < 0.01 1.00E00 1.00E00 liver morphogenesis (GO:0072576) 9 0 .00 - < 0.01 1.00E00 1.00E00 response to phenylpropanoid (GO:0080184) 6 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in liver morphogenesis (GO:0072575) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of regulated secretory pathway (GO:1903307) 47 0 .01 - < 0.01 1.00E00 1.00E00 hepatocyte proliferation (GO:0072574) 7 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of regulated secretory pathway (GO:1903306) 25 0 .01 - < 0.01 1.00E00 1.00E00 tolerance induction to lipopolysaccharide (GO:0072573) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of regulated secretory pathway (GO:1903305) 127 0 .04 - < 0.01 1.00E00 1.00E00 peptidyl-proline hydroxylation (GO:0019511) 4 0 .00 - < 0.01 1.00E00 1.00E00 sex-chromosome dosage compensation (GO:0007549) 22 0 .01 - < 0.01 1.00E00 1.00E00 regulation of pyruvate kinase activity (GO:1903302) 1 0 .00 - < 0.01 1.00E00 1.00E00 sex differentiation (GO:0007548) 288 1 .08 + 11.91 8.11E-02 1.00E00 positive regulation of hexokinase activity (GO:1903301) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of hexokinase activity (GO:1903300) 3 0 .00 - < 0.01 1.00E00 1.00E00 primary sex determination, germ-line (GO:0007542) 2 0 .00 - < 0.01 1.00E00 1.00E00 aortic valve formation (GO:0003189) 2 0 .00 - < 0.01 1.00E00 1.00E00 heart valve formation (GO:0003188) 15 0 .00 - < 0.01 1.00E00 1.00E00 tricuspid valve morphogenesis (GO:0003186) 6 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial valve morphogenesis (GO:0003185) 1 0 .00 - < 0.01 1.00E00 1.00E00 layer formation in cerebral cortex (GO:0021819) 16 0 .00 - < 0.01 1.00E00 1.00E00 pulmonary valve morphogenesis (GO:0003184) 20 0 .01 - < 0.01 1.00E00 1.00E00 mitral valve morphogenesis (GO:0003183) 13 0 .00 - < 0.01 1.00E00 1.00E00 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration (GO:0021817) 3 0 .00 - < 0.01 1.00E00 1.00E00 coronary sinus valve morphogenesis (GO:0003182) 1 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular valve morphogenesis (GO:0003181) 27 0 .01 - < 0.01 1.00E00 1.00E00 extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration (GO:0021816) 2 0 .00 - < 0.01 1.00E00 1.00E00 aortic valve morphogenesis (GO:0003180) 39 0 .01 - < 0.01 1.00E00 1.00E00 modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration (GO:0021815) 5 0 .00 - < 0.01 1.00E00 1.00E00 cell motility involved in cerebral cortex radial glia guided migration (GO:0021814) 7 0 .00 - < 0.01 1.00E00 1.00E00 cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration (GO:0021813) 1 0 .00 - < 0.01 1.00E00 1.00E00 neuronal-glial interaction involved in cerebral cortex radial glia guided migration (GO:0021812) 2 0 .00 - < 0.01 1.00E00 1.00E00 L-methionine salvage from methylthioadenosine (GO:0019509) 5 0 .00 - < 0.01 1.00E00 1.00E00 lytic vacuole organization (GO:0080171) 104 1 .03 + 32.98 2.99E-02 1.00E00 hydrogen peroxide transmembrane transport (GO:0080170) 4 0 .00 - < 0.01 1.00E00 1.00E00 type B pancreatic cell maturation (GO:0072560) 4 0 .00 - < 0.01 1.00E00 1.00E00 lateral sprouting involved in mammary gland duct morphogenesis (GO:0060599) 2 0 .00 - < 0.01 1.00E00 1.00E00 primary sex determination (GO:0007538) 3 0 .00 - < 0.01 1.00E00 1.00E00 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis (GO:0060598) 1 0 .00 - < 0.01 1.00E00 1.00E00 mammary placode formation (GO:0060596) 3 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast growth factor receptor signaling pathway involved in mammary gland specification (GO:0060595) 2 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland specification (GO:0060594) 3 0 .00 - < 0.01 1.00E00 1.00E00 mammary gland formation (GO:0060592) 7 0 .00 - < 0.01 1.00E00 1.00E00 chondroblast differentiation (GO:0060591) 5 0 .00 - < 0.01 1.00E00 1.00E00 sex determination (GO:0007530) 22 0 .01 - < 0.01 1.00E00 1.00E00 heart valve morphogenesis (GO:0003179) 63 0 .02 - < 0.01 1.00E00 1.00E00 coronary sinus valve development (GO:0003178) 1 0 .00 - < 0.01 1.00E00 1.00E00 pulmonary valve development (GO:0003177) 24 0 .01 - < 0.01 1.00E00 1.00E00 aortic valve development (GO:0003176) 45 0 .01 - < 0.01 1.00E00 1.00E00 tricuspid valve development (GO:0003175) 7 0 .00 - < 0.01 1.00E00 1.00E00 mitral valve development (GO:0003174) 14 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial valve development (GO:0003172) 2 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular valve development (GO:0003171) 30 0 .01 - < 0.01 1.00E00 1.00E00 heart valve development (GO:0003170) 76 0 .02 - < 0.01 1.00E00 1.00E00 cerebral cortex radial glia-guided migration (GO:0021801) 28 0 .01 - < 0.01 1.00E00 1.00E00 cerebral cortex tangential migration (GO:0021800) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nitric oxide metabolic process (GO:0080164) 62 0 .02 - < 0.01 1.00E00 1.00E00 blood vessel lumenization (GO:0072554) 2 0 .00 - < 0.01 1.00E00 1.00E00 terminal button organization (GO:0072553) 5 0 .00 - < 0.01 1.00E00 1.00E00 establishment of synaptic specificity at neuromuscular junction (GO:0007529) 2 0 .00 - < 0.01 1.00E00 1.00E00 neuromuscular junction development (GO:0007528) 43 0 .01 - < 0.01 1.00E00 1.00E00 negative regulation of lipoprotein lipid oxidation (GO:0060588) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of lipoprotein lipid oxidation (GO:0060587) 2 0 .00 - < 0.01 1.00E00 1.00E00 multicellular organismal-level iron ion homeostasis (GO:0060586) 28 0 .01 - < 0.01 1.00E00 1.00E00 somatic muscle development (GO:0007525) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of prostaglandin-endoperoxide synthase activity (GO:0060585) 2 0 .00 - < 0.01 1.00E00 1.00E00 cell fate determination involved in pattern specification (GO:0060582) 1 0 .00 - < 0.01 1.00E00 1.00E00 visceral muscle development (GO:0007522) 1 0 .00 - < 0.01 1.00E00 1.00E00 cell fate commitment involved in pattern specification (GO:0060581) 11 0 .00 - < 0.01 1.00E00 1.00E00 muscle cell fate determination (GO:0007521) 2 0 .00 - < 0.01 1.00E00 1.00E00 ventral spinal cord interneuron fate determination (GO:0060580) 1 0 .00 - < 0.01 1.00E00 1.00E00 myoblast fusion (GO:0007520) 30 0 .01 - < 0.01 1.00E00 1.00E00 coronary vein morphogenesis (GO:0003169) 2 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte differentiation (GO:0003168) 1 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular bundle cell differentiation (GO:0003167) 3 0 .00 - < 0.01 1.00E00 1.00E00 bundle of His development (GO:0003166) 6 0 .00 - < 0.01 1.00E00 1.00E00 Purkinje myocyte development (GO:0003165) 3 0 .00 - < 0.01 1.00E00 1.00E00 His-Purkinje system development (GO:0003164) 7 0 .00 - < 0.01 1.00E00 1.00E00 sinoatrial node development (GO:0003163) 12 0 .00 - < 0.01 1.00E00 1.00E00 atrioventricular node development (GO:0003162) 9 0 .00 - < 0.01 1.00E00 1.00E00 cardiac conduction system development (GO:0003161) 37 0 .01 - < 0.01 1.00E00 1.00E00 endocardium morphogenesis (GO:0003160) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of fertilization (GO:0080154) 17 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 17 cell lineage commitment (GO:0072540) 10 0 .00 - < 0.01 1.00E00 1.00E00 ventral spinal cord interneuron fate commitment (GO:0060579) 11 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle tissue development (GO:0007519) 146 1 .04 + 23.49 4.18E-02 1.00E00 myoblast fate determination (GO:0007518) 2 0 .00 - < 0.01 1.00E00 1.00E00 muscle organ development (GO:0007517) 318 1 .09 + 10.79 8.92E-02 1.00E00 pulmonary vein morphogenesis (GO:0060577) 1 0 .00 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell development (GO:0060576) 16 0 .00 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell differentiation (GO:0060575) 26 0 .01 - < 0.01 1.00E00 1.00E00 intestinal epithelial cell maturation (GO:0060574) 6 0 .00 - < 0.01 1.00E00 1.00E00 cell fate specification involved in pattern specification (GO:0060573) 7 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of an epithelial bud (GO:0060572) 7 0 .00 - < 0.01 1.00E00 1.00E00 adult heart development (GO:0007512) 14 0 .00 - < 0.01 1.00E00 1.00E00 morphogenesis of an epithelial fold (GO:0060571) 18 0 .01 - < 0.01 1.00E00 1.00E00 morphogenesis of an endothelium (GO:0003159) 12 0 .00 - < 0.01 1.00E00 1.00E00 endothelium development (GO:0003158) 105 0 .03 - < 0.01 1.00E00 1.00E00 endocardium development (GO:0003157) 12 0 .00 - < 0.01 1.00E00 1.00E00 regulation of animal organ formation (GO:0003156) 29 0 .01 - < 0.01 1.00E00 1.00E00 outflow tract morphogenesis (GO:0003151) 78 0 .02 - < 0.01 1.00E00 1.00E00 muscular septum morphogenesis (GO:0003150) 4 0 .00 - < 0.01 1.00E00 1.00E00 glycolate catabolic process (GO:0046296) 1 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 17 cell differentiation (GO:0072539) 14 0 .00 - < 0.01 1.00E00 1.00E00 glycolate biosynthetic process (GO:0046295) 1 0 .00 - < 0.01 1.00E00 1.00E00 T-helper 17 type immune response (GO:0072538) 18 0 .01 - < 0.01 1.00E00 1.00E00 formaldehyde catabolic process (GO:0046294) 3 0 .00 - < 0.01 1.00E00 1.00E00 fibroblast activation (GO:0072537) 9 0 .00 - < 0.01 1.00E00 1.00E00 formaldehyde biosynthetic process (GO:0046293) 1 0 .00 - < 0.01 1.00E00 1.00E00 formaldehyde metabolic process (GO:0046292) 4 0 .00 - < 0.01 1.00E00 1.00E00 intracellular amino acid homeostasis (GO:0080144) 9 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound transmembrane transport (GO:0072531) 16 0 .00 - < 0.01 1.00E00 1.00E00 purine-containing compound transmembrane transport (GO:0072530) 39 0 .01 - < 0.01 1.00E00 1.00E00 mesoderm migration involved in gastrulation (GO:0007509) 2 0 .00 - < 0.01 1.00E00 1.00E00 heart development (GO:0007507) 568 0 .17 - < 0.01 1.00E00 1.00E00 negative regulation of termination of DNA-templated transcription (GO:0060567) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of postsynaptic density protein 95 clustering (GO:1902897) 4 0 .00 - < 0.01 1.00E00 1.00E00 gonadal mesoderm development (GO:0007506) 9 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of termination of DNA-templated transcription (GO:0060566) 2 0 .00 - < 0.01 1.00E00 1.00E00 terminal web assembly (GO:1902896) 3 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of miRNA transcription (GO:1902895) 56 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of miRNA transcription (GO:1902894) 28 0 .01 - < 0.01 1.00E00 1.00E00 neuroepithelial cell differentiation (GO:0060563) 36 0 .01 - < 0.01 1.00E00 1.00E00 regulation of miRNA transcription (GO:1902893) 76 0 .02 - < 0.01 1.00E00 1.00E00 epithelial tube morphogenesis (GO:0060562) 313 0 .09 - < 0.01 1.00E00 1.00E00 apoptotic process involved in morphogenesis (GO:0060561) 19 0 .01 - < 0.01 1.00E00 1.00E00 mesodermal cell fate specification (GO:0007501) 8 0 .00 - < 0.01 1.00E00 1.00E00 developmental growth involved in morphogenesis (GO:0060560) 141 0 .04 - < 0.01 1.00E00 1.00E00 mesodermal cell fate determination (GO:0007500) 3 0 .00 - < 0.01 1.00E00 1.00E00 membranous septum morphogenesis (GO:0003149) 8 0 .00 - < 0.01 1.00E00 1.00E00 outflow tract septum morphogenesis (GO:0003148) 26 0 .01 - < 0.01 1.00E00 1.00E00 neural crest cell migration involved in heart formation (GO:0003147) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic heart tube formation (GO:0003144) 1 0 .00 - < 0.01 1.00E00 1.00E00 embryonic heart tube morphogenesis (GO:0003143) 70 0 .02 - < 0.01 1.00E00 1.00E00 cardiogenic plate morphogenesis (GO:0003142) 1 0 .00 - < 0.01 1.00E00 1.00E00 determination of left/right asymmetry in lateral mesoderm (GO:0003140) 9 0 .00 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound catabolic process (GO:0072529) 29 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound biosynthetic process (GO:0072528) 44 0 .01 - < 0.01 1.00E00 1.00E00 pyrimidine-containing compound metabolic process (GO:0072527) 76 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cellular response to stress (GO:0080135) 529 0 .15 - < 0.01 1.00E00 1.00E00 pyridine-containing compound catabolic process (GO:0072526) 55 0 .02 - < 0.01 1.00E00 1.00E00 regulation of response to stress (GO:0080134) 1426 1 .42 + 2.41 3.50E-01 1.00E00 pyridine-containing compound biosynthetic process (GO:0072525) 31 0 .01 - < 0.01 1.00E00 1.00E00 pyridine-containing compound metabolic process (GO:0072524) 136 0 .04 - < 0.01 1.00E00 1.00E00 purine-containing compound catabolic process (GO:0072523) 107 0 .03 - < 0.01 1.00E00 1.00E00 purine-containing compound biosynthetic process (GO:0072522) 239 0 .07 - < 0.01 1.00E00 1.00E00 purine-containing compound metabolic process (GO:0072521) 508 0 .15 - < 0.01 1.00E00 1.00E00 seminiferous tubule development (GO:0072520) 17 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of calcidiol 1-monooxygenase activity (GO:0060559) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of calcidiol 1-monooxygenase activity (GO:0060558) 7 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to spindle microtubule (GO:1902889) 2 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of vitamin D biosynthetic process (GO:0060557) 2 0 .00 - < 0.01 1.00E00 1.00E00 protein localization to astral microtubule (GO:1902888) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vitamin D biosynthetic process (GO:0060556) 7 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of response to oxidative stress (GO:1902884) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of response to oxidative stress (GO:1902883) 12 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fructose 1,6-bisphosphate metabolic process (GO:0060552) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of response to oxidative stress (GO:1902882) 35 0 .01 - < 0.01 1.00E00 1.00E00 regulation of fructose 1,6-bisphosphate metabolic process (GO:0060551) 1 0 .00 - < 0.01 1.00E00 1.00E00 secondary heart field specification (GO:0003139) 11 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity (GO:0060550) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary heart field specification (GO:0003138) 3 0 .00 - < 0.01 1.00E00 1.00E00 endodermal-mesodermal cell signaling (GO:0003133) 2 0 .00 - < 0.01 1.00E00 1.00E00 mesodermal-endodermal cell signaling (GO:0003131) 1 0 .00 - < 0.01 1.00E00 1.00E00 proteasome core complex assembly (GO:0080129) 1 0 .00 - < 0.01 1.00E00 1.00E00 flavonoid catabolic process (GO:0046275) 1 0 .00 - < 0.01 1.00E00 1.00E00 stilbene catabolic process (GO:0046272) 1 0 .00 - < 0.01 1.00E00 1.00E00 phenylpropanoid catabolic process (GO:0046271) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of secondary heart field cardioblast proliferation (GO:0072513) 3 0 .00 - < 0.01 1.00E00 1.00E00 AMP transport (GO:0080121) 2 0 .00 - < 0.01 1.00E00 1.00E00 CAAX-box protein maturation (GO:0080120) 4 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of necroptotic process (GO:0060546) 16 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of necroptotic process (GO:0060545) 6 0 .00 - < 0.01 1.00E00 1.00E00 regulation of necroptotic process (GO:0060544) 27 0 .01 - < 0.01 1.00E00 1.00E00 regulation of strand invasion (GO:0060542) 1 0 .00 - < 0.01 1.00E00 1.00E00 respiratory system development (GO:0060541) 220 0 .06 - < 0.01 1.00E00 1.00E00 positive regulation of amacrine cell differentiation (GO:1902871) 3 0 .00 - < 0.01 1.00E00 1.00E00 heart induction (GO:0003129) 8 0 .00 - < 0.01 1.00E00 1.00E00 heart field specification (GO:0003128) 12 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amacrine cell differentiation (GO:1902870) 3 0 .00 - < 0.01 1.00E00 1.00E00 detection of nodal flow (GO:0003127) 3 0 .00 - < 0.01 1.00E00 1.00E00 diaphragm development (GO:0060539) 9 0 .00 - < 0.01 1.00E00 1.00E00 regulation of amacrine cell differentiation (GO:1902869) 6 0 .00 - < 0.01 1.00E00 1.00E00 skeletal muscle organ development (GO:0060538) 160 1 .05 + 21.44 4.58E-02 1.00E00 muscle tissue development (GO:0060537) 349 1 .10 + 9.83 9.75E-02 1.00E00 cartilage morphogenesis (GO:0060536) 10 0 .00 - < 0.01 1.00E00 1.00E00 trachea cartilage morphogenesis (GO:0060535) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of retina development in camera-type eye (GO:1902866) 1 0 .00 - < 0.01 1.00E00 1.00E00 trachea cartilage development (GO:0060534) 7 0 .00 - < 0.01 1.00E00 1.00E00 bronchus cartilage development (GO:0060532) 2 0 .00 - < 0.01 1.00E00 1.00E00 propionyl-CoA biosynthetic process (GO:1902860) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vasoconstriction by circulating norepinephrine (GO:0003117) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of vasoconstriction by norepinephrine (GO:0003116) 1 0 .00 - < 0.01 1.00E00 1.00E00 response to disaccharide (GO:0034285) 9 0 .00 - < 0.01 1.00E00 1.00E00 squamous basal epithelial stem cell differentiation involved in prostate gland acinus development (GO:0060529) 2 0 .00 - < 0.01 1.00E00 1.00E00 propionyl-CoA catabolic process (GO:1902859) 2 0 .00 - < 0.01 1.00E00 1.00E00 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development (GO:0060528) 3 0 .00 - < 0.01 1.00E00 1.00E00 response to monosaccharide (GO:0034284) 152 0 .04 - < 0.01 1.00E00 1.00E00 propionyl-CoA metabolic process (GO:1902858) 4 0 .00 - < 0.01 1.00E00 1.00E00 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:0060527) 6 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of non-motile cilium assembly (GO:1902857) 8 0 .00 - < 0.01 1.00E00 1.00E00 prostate glandular acinus morphogenesis (GO:0060526) 6 0 .00 - < 0.01 1.00E00 1.00E00 prostate glandular acinus development (GO:0060525) 10 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of non-motile cilium assembly (GO:1902856) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of non-motile cilium assembly (GO:1902855) 11 0 .00 - < 0.01 1.00E00 1.00E00 prostate epithelial cord elongation (GO:0060523) 3 0 .00 - < 0.01 1.00E00 1.00E00 microtubule cytoskeleton organization involved in mitosis (GO:1902850) 135 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of the force of heart contraction by chemical signal (GO:0003108) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of glomerular filtration (GO:0003105) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of glomerular filtration (GO:0003104) 3 0 .00 - < 0.01 1.00E00 1.00E00 regulation of systemic arterial blood pressure by endothelin (GO:0003100) 6 0 .00 - < 0.01 1.00E00 1.00E00 terpene catabolic process (GO:0046247) 2 0 .00 - < 0.01 1.00E00 1.00E00 kynurenic acid biosynthetic process (GO:0034276) 2 0 .00 - < 0.01 1.00E00 1.00E00 kynurenic acid metabolic process (GO:0034275) 2 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in prostatic bud elongation (GO:0060517) 1 0 .00 - < 0.01 1.00E00 1.00E00 primary prostatic bud elongation (GO:0060516) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of neuronal signal transduction (GO:1902847) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of mitotic spindle elongation (GO:1902846) 1 0 .00 - < 0.01 1.00E00 1.00E00 prostate induction (GO:0060514) 1 0 .00 - < 0.01 1.00E00 1.00E00 prostatic bud formation (GO:0060513) 4 0 .00 - < 0.01 1.00E00 1.00E00 prostate gland morphogenesis (GO:0060512) 25 0 .01 - < 0.01 1.00E00 1.00E00 type II pneumocyte differentiation (GO:0060510) 6 0 .00 - < 0.01 1.00E00 1.00E00 type I pneumocyte differentiation (GO:0060509) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of nuclear migration along microtubule (GO:1902838) 1 0 .00 - < 0.01 1.00E00 1.00E00 smoothened signaling pathway involved in lung development (GO:0060506) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of proline import across plasma membrane (GO:1902836) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of GTPase activity (GO:0034260) 18 0 .01 - < 0.01 1.00E00 1.00E00 bud dilation involved in lung branching (GO:0060503) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of proline import across plasma membrane (GO:1902834) 2 0 .00 - < 0.01 1.00E00 1.00E00 epithelial cell proliferation involved in lung morphogenesis (GO:0060502) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of epithelial cell proliferation involved in lung morphogenesis (GO:0060501) 5 0 .00 - < 0.01 1.00E00 1.00E00 coumarin catabolic process (GO:0046226) 1 0 .00 - < 0.01 1.00E00 1.00E00 aflatoxin catabolic process (GO:0046223) 1 0 .00 - < 0.01 1.00E00 1.00E00 aflatoxin metabolic process (GO:0046222) 7 0 .00 - < 0.01 1.00E00 1.00E00 regulation of urea metabolic process (GO:0034255) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of amide metabolic process (GO:0034250) 31 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of late endosome to lysosome transport (GO:1902824) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of late endosome to lysosome transport (GO:1902823) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of late endosome to lysosome transport (GO:1902822) 3 0 .00 - < 0.01 1.00E00 1.00E00 indolalkylamine biosynthetic process (GO:0046219) 2 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide catabolic process (GO:0046210) 1 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of amide metabolic process (GO:0034249) 24 0 .01 - < 0.01 1.00E00 1.00E00 regulation of amide metabolic process (GO:0034248) 71 0 .02 - < 0.01 1.00E00 1.00E00 snoRNA splicing (GO:0034247) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of transcription elongation by RNA polymerase II (GO:0034244) 19 0 .01 - < 0.01 1.00E00 1.00E00 regulation of transcription elongation by RNA polymerase II (GO:0034243) 87 0 .03 - < 0.01 1.00E00 1.00E00 negative regulation of protein localization to microtubule (GO:1902817) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of syncytium formation by plasma membrane fusion (GO:0034242) 4 0 .00 - < 0.01 1.00E00 1.00E00 regulation of protein localization to microtubule (GO:1902816) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of macrophage fusion (GO:0034241) 5 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of skeletal muscle fiber differentiation (GO:1902811) 3 0 .00 - < 0.01 1.00E00 1.00E00 nitric oxide metabolic process (GO:0046209) 32 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of immune effector process (GO:0002699) 267 0 .08 - < 0.01 1.00E00 1.00E00 negative regulation of immune effector process (GO:0002698) 133 0 .04 - < 0.01 1.00E00 1.00E00 spermine catabolic process (GO:0046208) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of immune effector process (GO:0002697) 410 0 .12 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte activation (GO:0002696) 367 0 .11 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte activation (GO:0002695) 198 0 .06 - < 0.01 1.00E00 1.00E00 regulation of leukocyte activation (GO:0002694) 584 0 .17 - < 0.01 1.00E00 1.00E00 nor-spermidine metabolic process (GO:0046204) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cellular extravasation (GO:0002693) 19 0 .01 - < 0.01 1.00E00 1.00E00 spermidine catabolic process (GO:0046203) 2 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of cellular extravasation (GO:0002692) 8 0 .00 - < 0.01 1.00E00 1.00E00 regulation of cellular extravasation (GO:0002691) 41 0 .01 - < 0.01 1.00E00 1.00E00 positive regulation of leukocyte chemotaxis (GO:0002690) 97 0 .03 - < 0.01 1.00E00 1.00E00 regulation of macrophage fusion (GO:0034239) 5 0 .00 - < 0.01 1.00E00 1.00E00 macrophage fusion (GO:0034238) 1 0 .00 - < 0.01 1.00E00 1.00E00 regulation of skeletal muscle fiber differentiation (GO:1902809) 4 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of cell cycle G1/S phase transition (GO:1902808) 59 0 .02 - < 0.01 1.00E00 1.00E00 negative regulation of cell cycle G1/S phase transition (GO:1902807) 64 0 .02 - < 0.01 1.00E00 1.00E00 regulation of cell cycle G1/S phase transition (GO:1902806) 177 0 .05 - < 0.01 1.00E00 1.00E00 islet amyloid polypeptide processing (GO:0034231) 1 0 .00 - < 0.01 1.00E00 1.00E00 positive regulation of synaptic vesicle transport (GO:1902805) 2 0 .00 - < 0.01 1.00E00 1.00E00 enkephalin processing (GO:0034230) 2 0 .00 - < 0.01 1.00E00 1.00E00 regulation of synaptic vesicle transport (GO:1902803) 5 0 .00 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte chemotaxis (GO:0002689) 20 1 .01 + > 100 5.82E-03 1.00E00 regulation of leukocyte chemotaxis (GO:0002688) 124 1 .04 + 27.66 3.56E-02 1.00E00 positive regulation of leukocyte migration (GO:0002687) 154 0 .04 - < 0.01 1.00E00 1.00E00 negative regulation of leukocyte migration (GO:0002686) 51 1 .01 + 67.25 1.48E-02 1.00E00 regulation of leukocyte migration (GO:0002685) 231 1 .07 + 14.85 6.55E-02 1.00E00 positive regulation of immune system process (GO:0002684) 1033 0 .30 - < 0.01 1.00E00 1.00E00 negative regulation of immune system process (GO:0002683) 534 1 .16 + 6.42 1.46E-01 1.00E00 regulation of immune system process (GO:0002682) 1630 1 .48 + 2.10 3.91E-01 1.00E00 somatic recombination of T cell receptor gene segments (GO:0002681) 4 0 .00 - < 0.01 1.00E00 1.00E00 ethanolamine transport (GO:0034229) 4 0 .00 - < 0.01 1.00E00 1.00E00 tRNA thio-modification (GO:0034227) 5 0 .00 - < 0.01 1.00E00 1.00E00 cellular response to zinc ion starvation (GO:0034224) 9 0 .00 - < 0.01 1.00E00 1.00E00