1: Shirasaki T, Honda M, Mizuno H, Shimakami T, Okada H, Sakai Y, Murakami S, Wakita T, Kaneko S. La Protein Required for Internal Ribosome Entry Site-Directed Translation Is a Potential Therapeutic Target for Hepatitis C Virus Replication. J Infect Dis. 2010 May 24. [Epub ahead of print] PubMed PMID: 20497049. 2: Abe N, Sugiyama M, Mizuno H, Suzuki Y, Masaki T, Mori T, Atomi Y. Advanced ampullary carcinoma showing complete response to S-1: report of a case. Surg Today. 2010 Jun;40(6):574-7. Epub 2010 May 23. PubMed PMID: 20496142. 3: Antoku Y, Hotta J, Mizuno H, Dickson RM, Hofkens J, Vosch T. Transfection of living HeLa cells with fluorescent poly-cytosine encapsulated Ag nanoclusters. Photochem Photobiol Sci. 2010 May;9(5):716-21. Epub 2010 Mar 22. PubMed PMID: 20442932. 4: Suzuki N, Mizuno H, Warita H, Takeda S, Itoyama Y, Aoki M. Neuronal NOS is dislocated during muscle atrophy in amyotrophic lateral sclerosis. J Neurol Sci. 2010 Apr 30. [Epub ahead of print] PubMed PMID: 20435320. 5: Adam V, Mizuno H, Grichine A, Hotta JI, Yamagata Y, Moeyaert B, Nienhaus GU, Miyawaki A, Bourgeois D, Hofkens J. Data storage based on photochromic and photoconvertible fluorescent proteins. J Biotechnol. 2010 Apr 21. [Epub ahead of print] PubMed PMID: 20416344. 6: Mizuno H, Atwal G, Wang H, Levine AJ, Vazquez A. Fine-scale detection of population-specific linkage disequilibrium using haplotype entropy in the human genome. BMC Genet. 2010 Apr 23;11:27. PubMed PMID: 20416085; PubMed Central PMCID: PMC2873552. 7: Mizuno H, Buriak JM. Nanoscale patterning of organic monolayers by catalytic stamp lithography: scope and limitations. ACS Appl Mater Interfaces. 2009 Dec;1(12):2711-20. PubMed PMID: 20356148. 8: Saito Y, Sekine W, Sano R, Komatsu S, Mizuno H, Katabami K, Shimada K, Oku T, Tsuji T. Potentiation of cell invasion and matrix metalloproteinase production by alpha3beta1 integrin-mediated adhesion of gastric carcinoma cells to laminin-5. Clin Exp Metastasis. 2010 Apr;27(4):197-205. Epub 2010 Mar 30. PubMed PMID: 20352300. 9: Mizuno H, Kagami H, Mase J, Mizuno D, Ueda M. Efficacy of membranous cultured periosteum for the treatment of patients with severe periodontitis: a proof-of-concept study. Nagoya J Med Sci. 2010 Feb;72(1-2):59-70. PubMed PMID: 20229704. 10: Suzuki N, Aoki M, Warita H, Kato M, Mizuno H, Shimakura N, Akiyama T, Furuya H, Hokonohara T, Iwaki A, Togashi S, Konno H, Itoyama Y. FALS with FUS mutation in Japan, with early onset, rapid progress and basophilic inclusion. J Hum Genet. 2010 Apr;55(4):252-4. Epub 2010 Mar 12. PubMed PMID: 20224596. 11: Mizushima T, Nomura M, Fujii M, Akamatsu H, Mizuno H, Tominaga H, Hasegawa J, Nakajima K, Yasumasa K, Yoshikawa M, Nishida T. Primary colorectal signet-ring cell carcinoma: clinicopathological features and postoperative survival. Surg Today. 2010 Mar;40(3):234-8. Epub 2010 Feb 24. PubMed PMID: 20180076. 12: Mizuno H, Dedecker P, Ando R, Fukano T, Hofkens J, Miyawaki A. Higher resolution in localization microscopy by slower switching of a photochromic protein. Photochem Photobiol Sci. 2010 Feb;9(2):239-48. Epub 2010 Jan 18. PubMed PMID: 20126801. 13: Mizuno H, Hirano T, Tagawa Y. Pre-synaptic and post-synaptic neuronal activity supports the axon development of callosal projection neurons during different post-natal periods in the mouse cerebral cortex. Eur J Neurosci. 2010 Feb;31(3):410-24. Epub 2010 Jan 25. PubMed PMID: 20105242. 14: Mizuno H, Miyamoto M, Shimamoto M, Koike S, Hyakusoku H, Kuroyanagi Y. Therapeutic angiogenesis by autologous bone marrow cell implantation together with allogeneic cultured dermal substitute for intractable ulcers in critical limb ischaemia. J Plast Reconstr Aesthet Surg. 2010 Jan 7. [Epub ahead of print] PubMed PMID: 20060793. 15: Okuda T, Uysal AC, Tobita M, Hyakusoku H, Mizuno H. Prefabrication of tissue engineered bone grafts: an experimental study. Ann Plast Surg. 2010 Jan;64(1):98-104. PubMed PMID: 20010414. 16: Kawashima H, Numakawa T, Kumamaru E, Adachi N, Mizuno H, Ninomiya M, Kunugi H, Hashido K. Glucocorticoid attenuates brain-derived neurotrophic factor-dependent upregulation of glutamate receptors via the suppression of microRNA-132 expression. Neuroscience. 2010 Feb 17;165(4):1301-11. Epub 2009 Dec 1. PubMed PMID: 19958814. 17: Tsutsui H, Shimizu H, Mizuno H, Nukina N, Furuta T, Miyawaki A. The E1 mechanism in photo-induced beta-elimination reactions for green-to-red conversion of fluorescent proteins. Chem Biol. 2009 Nov 25;16(11):1140-7. PubMed PMID: 19942137. 18: Mizuno H. The Potential for Treatment of Skeletal Muscle Disorders with Adipose-Derived Stem Cells. Curr Stem Cell Res Ther. 2009 Nov 26. [Epub ahead of print] PubMed PMID: 19941455. 19: Uysal AC, Mizuno H. Tendon Regeneration and Repair with Adipose Derived Stem Cells. Curr Stem Cell Res Ther. 2009 Nov 26. [Epub ahead of print] PubMed PMID: 19941450. 20: Tobita M, Mizuno H. Periodontal Disease and Periodontal Tissue Regeneration. Curr Stem Cell Res Ther. 2009 Nov 26. [Epub ahead of print] PubMed PMID: 19941449. 21: Li X, Chung LW, Mizuno H, Miyawaki A, Morokuma K. A theoretical study on the nature of on- and off-states of reversibly photoswitching fluorescent protein Dronpa: absorption, emission, protonation, and Raman. J Phys Chem B. 2010 Jan 21;114(2):1114-26. PubMed PMID: 19902912. 22: Ageta-Ishihara N, Takemoto-Kimura S, Nonaka M, Adachi-Morishima A, Suzuki K, Kamijo S, Fujii H, Mano T, Blaeser F, Chatila TA, Mizuno H, Hirano T, Tagawa Y, Okuno H, Bito H. Control of cortical axon elongation by a GABA-driven Ca2+/calmodulin-dependent protein kinase cascade. J Neurosci. 2009 Oct 28;29(43):13720-9. PubMed PMID: 19864584; PubMed Central PMCID: PMC2796271. 23: Kato S, Ohno T, Thephamongkhol K, Chansilpa Y, Yuxing Y, Devi CR, Bustam AZ, Calaguas MJ, de Los Reyes RH, Cho CK, Dung TA, Supriana N, Mizuno H, Nakano T, Tsujii H. Multi-Institutional Phase II Clinical Study of Concurrent Chemoradiotherapy for Locally Advanced Cervical Cancer in East and Southeast Asia. Int J Radiat Oncol Biol Phys. 2009 Oct 14. [Epub ahead of print] PubMed PMID: 19836154. 24: Fukumura A, Tsujii H, Kamada T, Baba M, Tsuji H, Kato H, Kato S, Yamada S, Yasuda S, Yanagi T, Kato H, Hara R, Yamamoto N, Mizoe J, Akahane K, Fukuda S, Furusawa Y, Iwata Y, Kanai T, Kanematsu N, Kitagawa A, Matsufuji N, Minohara S, Miyahara N, Mizuno H, Murakami T, Nishizawa K, Noda K, Takada E, Yonai S. Carbon-ion radiotherapy: clinical aspects and related dosimetry. Radiat Prot Dosimetry. 2009;137(1-2):149-55. Epub 2009 Oct 7. Review. PubMed PMID: 19812127. 25: Teramoto H, Mizuno H, Yogo H, Hori S, Nakayama S. Assessment of gastric motility using magnetic resonance imaging in patients receiving enteral nutrition. J Am Geriatr Soc. 2009 Oct;57(10):1965-6. PubMed PMID: 19807816. 26: Okuda K, Yamamiya K, Kawase T, Mizuno H, Ueda M, Yoshie H. Treatment of human infrabony periodontal defects by grafting human cultured periosteum sheets combined with platelet-rich plasma and porous hydroxyapatite granules: case series. J Int Acad Periodontol. 2009 Jul;11(3):206-13. PubMed PMID: 19753798. 27: Lorenzo Tejedor M, Mizuno H, Tsuyama N, Harada T, Masujima T. Direct single-cell molecular analysis of plant tissues by video mass spectrometry. Anal Sci. 2009 Sep;25(9):1053-5. PubMed PMID: 19745529. 28: Uysal AC, Mizuno H, Tobita M, Ogawa R, Hyakusoku H. The effect of adipose-derived stem cells on ischemia-reperfusion injury: immunohistochemical and ultrastructural evaluation. Plast Reconstr Surg. 2009 Sep;124(3):804-15. PubMed PMID: 19730299. 29: Iwata T, Suzuki N, Mizuno H, Nakashima I, Kanbayashi T, Itoyama Y. [A marked decrease of orexin in the cerebrospinal fluid in a patient with myotonic dystrophy type 1 showing an excessive daytime sleepiness]. Rinsho Shinkeigaku. 2009 Jul;49(7):437-9. Japanese. PubMed PMID: 19715174. 30: Wu J, Fujisawa M, Tian Z, Yamagata H, Kamiya K, Shibata M, Hosokawa S, Ito Y, Hamada M, Katagiri S, Kurita K, Yamamoto M, Kikuta A, Machita K, Karasawa W, Kanamori H, Namiki N, Mizuno H, Ma J, Sasaki T, Matsumoto T. Comparative analysis of complete orthologous centromeres from two subspecies of rice reveals rapid variation of centromere organization and structure. Plant J. 2009 Dec;60(5):805-19. Epub 2009 Aug 21. PubMed PMID: 19702669. 31: Kobayashi T, Mizuno H, Imayoshi I, Furusawa C, Shirahige K, Kageyama R. The cyclic gene Hes1 contributes to diverse differentiation responses of embryonic stem cells. Genes Dev. 2009 Aug 15;23(16):1870-5. PubMed PMID: 19684110; PubMed Central PMCID: PMC2725939. 32: Isobe K, Suda A, Tanaka M, Kannari F, Kawano H, Mizuno H, Miyawaki A, Midorikawa K. Multifarious control of two-photon excitation of multiple fluorophores achieved by phase modulation of ultra-broadband laser pulses. Opt Express. 2009 Aug 3;17(16):13737-46. PubMed PMID: 19654781. 33: Isobe K, Suda A, Tanaka M, Hashimoto H, Kannari F, Kawano H, Mizuno H, Miyawaki A, Midorikawa K. Single-pulse coherent anti-Stokes Raman scattering microscopy employing an octave spanning pulse. Opt Express. 2009 Jul 6;17(14):11259-66. PubMed PMID: 19582038. 34: Endo A, Mizuno H, Okada S. Monitoring the bacterial community during fermentation of sunki, an unsalted, fermented vegetable traditional to the Kiso area of Japan. Lett Appl Microbiol. 2008 Sep;47(3):221-6. PubMed PMID: 19552789. 35: Arima J, Sasaki C, Sakaguchi C, Mizuno H, Tamura T, Kashima A, Kusakabe H, Sugio S, Inagaki K. Structural characterization of L-glutamate oxidase from Streptomyces sp. X-119-6. FEBS J. 2009 Jul;276(14):3894-903. Epub 2009 Jun 15. PubMed PMID: 19531050. 36: Mizuno H, Kanda K, Sugiyama Y, Imamine H, Ito T, Kato I, Togari H, Kamoda T, Onigata K. Longitudinal evaluation of patients with a homozygous R450H mutation of the TSH receptor gene. Horm Res. 2009;71(6):318-23. Epub 2009 Jun 6. PubMed PMID: 19506388. 37: Uysal CA, Ogawa R, Vinh VQ, Mizuno H, Hyakusoku H. Vascular anatomy of the supraclavicular area revisited. Plast Reconstr Surg. 2009 Jun;123(6):1880-1; author reply 1881-2. PubMed PMID: 19483591. 38: Iwano M, Entani T, Shiba H, Kakita M, Nagai T, Mizuno H, Miyawaki A, Shoji T, Kubo K, Isogai A, Takayama S. Fine-tuning of the cytoplasmic Ca2+ concentration is essential for pollen tube growth. Plant Physiol. 2009 Jul;150(3):1322-34. Epub 2009 May 27. PubMed PMID: 19474213; PubMed Central PMCID: PMC2705041. 39: Suto K, Masuda H, Takenaka Y, Tsuji FI, Mizuno H. Structural basis for red-shifted emission of a GFP-like protein from the marine copepod Chiridius poppei. Genes Cells. 2009 Jun;14(6):727-37. Epub 2009 May 14. PubMed PMID: 19469881. 40: Mizuno H. Adipose-derived stem cells for tissue repair and regeneration: ten years of research and a literature review. J Nippon Med Sch. 2009 Apr;76(2):56-66. Review. PubMed PMID: 19443990. 41: Mizuno H, Kitada K, Nakai K, Sarai A. PrognoScan: a new database for meta-analysis of the prognostic value of genes. BMC Med Genomics. 2009 Apr 24;2:18. PubMed PMID: 19393097; PubMed Central PMCID: PMC2689870. 42: Itoi Y, Takatori M, Hyakusoku H, Mizuno H. Comparison of readily available scaffolds for adipose tissue engineering using adipose-derived stem cells. J Plast Reconstr Aesthet Surg. 2010 May;63(5):858-64. Epub 2009 Apr 14. PubMed PMID: 19369133. 43: Ohtsuka H, Ogawa Y, Mizuno H, Mita S, Aiba H. Identification of Ecl family genes that extend chronological lifespan in fission yeast. Biosci Biotechnol Biochem. 2009 Apr 23;73(4):885-9. Epub 2009 Apr 7. PubMed PMID: 19352039. 44: Ono H, Suzuki N, Mizuno H, Tateyama M, Aoki M, Itoyama Y. [Elevated serum aldolase activity in a patient of non-eosinophilic myofasciitis and synovitis with perifascicular atrophy]. Rinsho Shinkeigaku. 2009 Feb-Mar;49(2-3):119-22. Japanese. PubMed PMID: 19348178. 45: Uysal CA, Mizuno H, Hyakusoku H. Sciatic nerve anatomy in rat re-visited: a more proximal intervention. J Plast Reconstr Aesthet Surg. 2009 Jun;62(6):847-9. Epub 2009 Apr 2. PubMed PMID: 19345171. 46: Mizuno H, Nakanishi Y, Ishii N, Sarai A, Kitada K. A signature-based method for indexing cell cycle phase distribution from microarray profiles. BMC Genomics. 2009 Mar 30;10:137. PubMed PMID: 19331659; PubMed Central PMCID: PMC2676301. 47: Mizuno H, Nomoto S, Ishii N, Hyakusoku H, Fukuda R. Frontal musculocutaneous V-Y island flap for coverage of forehead defect with a dural exposure after craniotomy. J Nippon Med Sch. 2009 Feb;76(1):19-22. PubMed PMID: 19305106. 48: Nambu M, Kishimoto S, Nakamura S, Mizuno H, Yanagibayashi S, Yamamoto N, Azuma R, Nakamura S, Kiyosawa T, Ishihara M, Kanatani Y. Accelerated wound healing in healing-impaired db/db mice by autologous adipose tissue-derived stromal cells combined with atelocollagen matrix. Ann Plast Surg. 2009 Mar;62(3):317-21. PubMed PMID: 19240532. 49: Suzuki N, Mizuno H, Nezu M, Takai Y, Misu T, Kuroda H, Aoki M, Nakashima I, Itoyama Y. Procalcitonin might help in discrimination between meningeal neuro-Behçet disease and bacterial meningitis. Neurology. 2009 Feb 24;72(8):762-3. PubMed PMID: 19237707. 50: Nakatani D, Sakata Y, Mizuno H, Shimizu M, Suna S, Usami M, Ito H, Yasumura Y, Hirayama A, Takeda H, Hori M, Sato H; Osaka Acute Coronary Insufficiency Study (OACIS) Group. Impact of diabetes mellitus on rehospitalization for heart failure among survivors of acute myocardial infarction in the percutaneous coronary intervention era. Circ J. 2009 Apr;73(4):662-6. Epub 2009 Feb 19. PubMed PMID: 19225202. 51: Mizuno H, Akaishi S, Kobe K, Hyakusoku H. Secondary vascularised hairy flap transfer for eyebrow reconstruction. J Plast Reconstr Aesthet Surg. 2009 Dec;62(12):e625-6. Epub 2009 Feb 6. PubMed PMID: 19201269. 52: Ozaki K, Sato H, Inoue K, Tsunoda T, Sakata Y, Mizuno H, Lin TH, Miyamoto Y, Aoki A, Onouchi Y, Sheu SH, Ikegawa S, Odashiro K, Nobuyoshi M, Juo SH, Hori M, Nakamura Y, Tanaka T. SNPs in BRAP associated with risk of myocardial infarction in Asian populations. Nat Genet. 2009 Mar;41(3):329-33. Epub 2009 Feb 8. PubMed PMID: 19198608. 53: Yamamoto Y, Mizuno H, Tsuritani T, Mase T. Synthesis of alpha-chloroaldoxime O-methanesulfonates and their use in the synthesis of functionalized benzimidazoles. J Org Chem. 2009 Feb 6;74(3):1394-6. PubMed PMID: 19178358. 54: Mizuno K, Kojima Y, Kurokawa S, Mizuno H, Kohri K, Hayashi Y. Laparoscopic diagnosis and treatment of a phenotypic girl with mosaic 45,XO/46,X,idic(Y) mixed gonadal dysgenesis. J Pediatr Surg. 2009 Jan;44(1):e1-3. PubMed PMID: 19159702. 55: Mizuno H, Hirai H, Kawai S, Nishida T. Removal of estrogenic activity of iso-butylparaben and n-butylparaben by laccase in the presence of 1-hydroxybenzotriazole. Biodegradation. 2009 Jul;20(4):533-9. Epub 2008 Dec 25. PubMed PMID: 19109757. 56: Suna S, Sakata Y, Shimizu M, Nakatani D, Usami M, Matsumoto S, Mizuno H, Ozaki K, Takashima S, Takeda H, Tanaka T, Hori M, Sato H. Lymphotoxin-alpha3 mediates monocyte-endothelial interaction by TNFR I/NF-kappaB signaling. Biochem Biophys Res Commun. 2009 Feb 6;379(2):374-8. Epub 2008 Dec 25. PubMed PMID: 19103156. 57: Nezu M, Suzuki N, Mizuno H, Takai Y, Misu T, Aoki M, Nakashima I, Itoyama Y. [Case of Neuro-Behçet disease resembling bacterial meningitis]. Rinsho Shinkeigaku. 2008 Oct;48(10):750-3. Japanese. PubMed PMID: 19086433. 58: Mizuno H, Tsuyama N, Date S, Harada T, Masujima T. Live single-cell metabolomics of tryptophan and histidine metabolites in a rat basophil leukemia cell. Anal Sci. 2008 Dec;24(12):1525-7. PubMed PMID: 19075459. 59: Mizuno H, Buriak JM. Catalytic stamp lithography for sub-100 nm patterning of organic monolayers. J Am Chem Soc. 2008 Dec 31;130(52):17656-7. PubMed PMID: 19063631. 60: Omran H, Kobayashi D, Olbrich H, Tsukahara T, Loges NT, Hagiwara H, Zhang Q, Leblond G, O'Toole E, Hara C, Mizuno H, Kawano H, Fliegauf M, Yagi T, Koshida S, Miyawaki A, Zentgraf H, Seithe H, Reinhardt R, Watanabe Y, Kamiya R, Mitchell DR, Takeda H. Ktu/PF13 is required for cytoplasmic pre-assembly of axonemal dyneins. Nature. 2008 Dec 4;456(7222):611-6. PubMed PMID: 19052621. 61: Iwasaku T, Hirooka K, Taniguchi T, Hamano G, Utsunomiya Y, Nakagawa A, Koide M, Ishizu T, Yamato M, Sasaki N, Yamamoto H, Kawaguchi Y, Mizuno H, Koretsune Y, Kusuoka H, Yasumura Y. Successful catheter ablation to accessory atrioventricular pathway as cardiac resynchronization therapy in a patient with dilated cardiomyopathy. Europace. 2009 Jan;11(1):121-3. Epub 2008 Nov 20. PubMed PMID: 19028709. 62: Asselberghs I, Flors C, Ferrighi L, Botek E, Champagne B, Mizuno H, Ando R, Miyawaki A, Hofkens J, Van der Auweraer M, Clays K. Second-harmonic generation in GFP-like proteins. J Am Chem Soc. 2008 Nov 19;130(46):15713-9. Epub 2008 Oct 25. PubMed PMID: 18950177. 63: Shudai M, Fujii K, Kuroda J, Niwa S, Mizuno H, Wanibe M, Maeda T, Kimura K, Komatsu H, Hasegawa S. [Construction and evaluation of new anti-cancer drug prescription support system to promote proper use of anticancer drugs]. Gan To Kagaku Ryoho. 2008 Oct;35(10):1717-20. Japanese. PubMed PMID: 18931575. 64: Suzuki N, Yamazaki Y, Brown RL, Fujimoto Z, Morita T, Mizuno H. Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain. Acta Crystallogr D Biol Crystallogr. 2008 Oct;64(Pt 10):1034-42. Epub 2008 Sep 19. PubMed PMID: 18931410; PubMed Central PMCID: PMC2725782. 65: Kikuchi A, Fukumura E, Karasawa S, Mizuno H, Miyawaki A, Shiro Y. Structural characterization of a thiazoline-containing chromophore in an orange fluorescent protein, monomeric Kusabira Orange. Biochemistry. 2008 Nov 4;47(44):11573-80. Epub 2008 Oct 10. PubMed PMID: 18844376. 66: Maeda K, Kobayashi Y, Oie S, Ishida S, Okano Y, Kobayashi T, Shikichi K, Mizuno H, Kamiya A. Antimicrobial effects of drugs against multidrug-resistant Pseudomonas aeruginosa. Biol Pharm Bull. 2008 Oct;31(10):1898-901. PubMed PMID: 18827351. 67: Amirul Islam M, Yanagi T, Mizoe JE, Mizuno H, Tsujii H. Comparative study of dose distribution between carbon ion radiotherapy and photon radiotherapy for head and neck tumor. Radiat Med. 2008 Aug;26(7):415-21. Epub 2008 Sep 4. PubMed PMID: 18769999. 68: Tsigelny IF, Crews L, Desplats P, Shaked GM, Sharikov Y, Mizuno H, Spencer B, Rockenstein E, Trejo M, Platoshyn O, Yuan JX, Masliah E. Mechanisms of hybrid oligomer formation in the pathogenesis of combined Alzheimer's and Parkinson's diseases. PLoS One. 2008 Sep 4;3(9):e3135. PubMed PMID: 18769546; PubMed Central PMCID: PMC2519786. 69: Ghadamyari M, Talebi K, Mizuno H, Kono Y. Oxydemeton-methyl resistance, mechanisms, and associated fitness cost in green peach aphids (Hemiptera: Aphididae). J Econ Entomol. 2008 Aug;101(4):1432-8. PubMed PMID: 18767757. 70: Mizuno H, Sasaki T, Matsumoto T. Characterization of internal structure of the nucleolar organizing region in rice (Oryza sativa L.). Cytogenet Genome Res. 2008;121(3-4):282-5. Epub 2008 Aug 29. PubMed PMID: 18758172. 71: Takenaka Y, Masuda H, Yamaguchi A, Nishikawa S, Shigeri Y, Yoshida Y, Mizuno H. Two forms of secreted and thermostable luciferases from the marine copepod crustacean, Metridia pacifica. Gene. 2008 Dec 1;425(1-2):28-35. Epub 2008 Aug 7. PubMed PMID: 18725274. 72: Sugiyama Y, Mizuno H, Hayashi Y, Imamine H, Ito T, Kato I, Yamamoto-Tomita M, Aoyama M, Asai K, Togari H. Severity of virilization of external genitalia in Japanese patients with salt-wasting 21-hydroxylase deficiency. Tohoku J Exp Med. 2008 Aug;215(4):341-8. PubMed PMID: 18679008. 73: Mizushima T, Mizuno H, Sugiura T, Ito T, Udatsu Y, Okazawa M, Sugimura K, Tomokuni A, Kusumoto H, Nakagawa T, Kishimoto T, Iwase K, Izukura M. [Efficacy of 5-FU hepatic arterial infusion with l-leucovorin for patients with unresectable colorectal liver metastasis]. Gan To Kagaku Ryoho. 2008 Jul;35(7):1139-42. Japanese. PubMed PMID: 18633252. 74: Mizuno H, Tsuyama N, Harada T, Masujima T. Live single-cell video-mass spectrometry for cellular and subcellular molecular detection and cell classification. J Mass Spectrom. 2008 Dec;43(12):1692-700. PubMed PMID: 18615771. 75: Suna S, Sakata Y, Sato H, Mizuno H, Nakatani D, Shimizu M, Usami M, Takashima S, Takeda H, Hori M. Up-regulation of cell adhesion molecule genes in human endothelial cells stimulated by lymphotoxin alpha: DNA microarray analysis. J Atheroscler Thromb. 2008 Jun;15(3):160-5. PubMed PMID: 18603823. 76: Aoki S, Tanuma K, Iwakiri I, Mizuno H, Ogawa R, Ozawa H, Hyakusoku H. Clinical and vascular anatomical study of distally based sural flap. Ann Plast Surg. 2008 Jul;61(1):73-8. PubMed PMID: 18580154. 77: Mizuno H, Mal TK, Wälchli M, Kikuchi A, Fukano T, Ando R, Jeyakanthan J, Taka J, Shiro Y, Ikura M, Miyawaki A. Light-dependent regulation of structural flexibility in a photochromic fluorescent protein. Proc Natl Acad Sci U S A. 2008 Jul 8;105(27):9227-32. Epub 2008 Jun 23. PubMed PMID: 18574155; PubMed Central PMCID: PMC2453726. 78: Usami K, Mizuno H, Okada K, Narita Y, Aoki M, Kondo T, Mizuno D, Mase J, Nishiguchi H, Kagami H, Ueda M. Composite implantation of mesenchymal stem cells with endothelial progenitor cells enhances tissue-engineered bone formation. J Biomed Mater Res A. 2009 Sep 1;90(3):730-41. PubMed PMID: 18570318. 79: Tagawa Y, Mizuno H, Hirano T. Activity-dependent development of interhemispheric connections in the visual cortex. Rev Neurosci. 2008;19(1):19-28. Review. PubMed PMID: 18561818. 80: Tobita M, Uysal AC, Ogawa R, Hyakusoku H, Mizuno H. Periodontal tissue regeneration with adipose-derived stem cells. Tissue Eng Part A. 2008 Jun;14(6):945-53. PubMed PMID: 18558814. 81: Mizuno H, Ohte N, Wakami K, Narita H, Fukuta H, Asada K, Kimura G. Peak mitral annular velocity during early diastole and propagation velocity of early diastolic filling flow are not interchangeable as the parameters of left ventricular early diastolic function. Am J Cardiol. 2008 May 15;101(10):1467-71. Epub 2008 Mar 17. PubMed PMID: 18471459. 82: Tsuyama N, Mizuno H, Tokunaga E, Masujima T. Live single-cell molecular analysis by video-mass spectrometry. Anal Sci. 2008 May;24(5):559-61. PubMed PMID: 18469458. 83: Kawano H, Kogure T, Abe Y, Mizuno H, Miyawaki A. Two-photon dual-color imaging using fluorescent proteins. Nat Methods. 2008 May;5(5):373-4. PubMed PMID: 18446153. 84: Gopinath SC, Balasundaresan D, Kumarevel T, Misono TS, Mizuno H, Kumar PK. Insights into anti-termination regulation of the hut operon in Bacillus subtilis: importance of the dual RNA-binding surfaces of HutP. Nucleic Acids Res. 2008 Jun;36(10):3463-73. Epub 2008 Apr 29. PubMed PMID: 18445631; PubMed Central PMCID: PMC2425495. 85: Mizuno H, Warita H, Aoki M, Itoyama Y. Accumulation of chondroitin sulfate proteoglycans in the microenvironment of spinal motor neurons in amyotrophic lateral sclerosis transgenic rats. J Neurosci Res. 2008 Aug 15;86(11):2512-23. PubMed PMID: 18438943. 86: Crews L, Mizuno H, Desplats P, Rockenstein E, Adame A, Patrick C, Winner B, Winkler J, Masliah E. Alpha-synuclein alters Notch-1 expression and neurogenesis in mouse embryonic stem cells and in the hippocampus of transgenic mice. J Neurosci. 2008 Apr 16;28(16):4250-60. PubMed PMID: 18417705; PubMed Central PMCID: PMC2666311. 87: Mizuno H, Wu J, Katayose Y, Kanamori H, Sasaki T, Matsumoto T. Characterization of chromosome ends on the basis of the structure of TrsA subtelomeric repeats in rice (Oryza sativa L.). Mol Genet Genomics. 2008 Jul;280(1):19-24. Epub 2008 Apr 8. PubMed PMID: 18392854. 88: Furuichi M, Suzuki N, Dhakshnamoorhty B, Minagawa H, Yamagishi R, Watanabe Y, Goto Y, Kaneko H, Yoshida Y, Yagi H, Waga I, Kumar PK, Mizuno H. X-ray structures of Aerococcus viridans lactate oxidase and its complex with D-lactate at pH 4.5 show an alpha-hydroxyacid oxidation mechanism. J Mol Biol. 2008 Apr 25;378(2):436-46. Epub 2008 Mar 3. PubMed PMID: 18367206. 89: Hosoi H, Yamaguchi S, Mizuno H, Miyawaki A, Tahara T. Hidden electronic excited state of enhanced green fluorescent protein. J Phys Chem B. 2008 Mar 13;112(10):2761-3. Epub 2008 Feb 15. PubMed PMID: 18275187. 90: Yoshida Y, Sakai N, Masuda H, Furuichi M, Nishikawa F, Nishikawa S, Mizuno H, Waga I. Rabbit antibody detection with RNA aptamers. Anal Biochem. 2008 Apr 15;375(2):217-22. Epub 2008 Jan 9. PubMed PMID: 18252191. 91: Bar-On P, Crews L, Koob AO, Mizuno H, Adame A, Spencer B, Masliah E. Statins reduce neuronal alpha-synuclein aggregation in in vitro models of Parkinson's disease. J Neurochem. 2008 Jun;105(5):1656-67. Epub 2008 Jan 28. PubMed PMID: 18248604; PubMed Central PMCID: PMC2822545. 92: Kawahara K, Hashimoto M, Bar-On P, Ho GJ, Crews L, Mizuno H, Rockenstein E, Imam SZ, Masliah E. alpha-Synuclein aggregates interfere with Parkin solubility and distribution: role in the pathogenesis of Parkinson disease. J Biol Chem. 2008 Mar 14;283(11):6979-87. Epub 2008 Jan 14. PubMed PMID: 18195004. 93: Lu F, Mizuno H, Uysal CA, Cai X, Ogawa R, Hyakusoku H. Improved viability of random pattern skin flaps through the use of adipose-derived stem cells. Plast Reconstr Surg. 2008 Jan;121(1):50-8. PubMed PMID: 18176205. 94: Kanazawa T, Chana G, Glatt SJ, Mizuno H, Masliah E, Yoneda H, Tsuang MT, Everall IP. The utility of SELENBP1 gene expression as a biomarker for major psychotic disorders: replication in schizophrenia and extension to bipolar disorder with psychosis. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5;147B(6):686-9. PubMed PMID: 18163446. 95: Sato H, Kinjo K, Ito H, Hirayama A, Nanto S, Fukunami M, Nishino M, Lim YJ, Kijima Y, Koretsune Y, Nakatani D, Mizuno H, Shimizu M, Hori M; Osaka Acute Coronary Insufficiency Study (OACIS)-LIPID Study Investigators. Effect of early use of low-dose pravastatin on major adverse cardiac events in patients with acute myocardial infarction: the OACIS-LIPID Study. Circ J. 2008 Jan;72(1):17-22. PubMed PMID: 18159093. 96: Ogawa R, Hyakusoku H, Mizuno H, Murakami M, Aoki R. Lower leg reconstruction using three free flaps. Plast Reconstr Surg. 2007 Dec;120(7):2130-1. PubMed PMID: 18090804. 97: Shimizu M, Sato H, Sakata Y, Nakatani D, Mizuno H, Suna S, Fujii K, Ueda Y, Nanto S, Hori M; Osaka Acute Coronary Insufficiency Study (OACIS) Group. Effect on outcome of an increase of serum cardiac troponin T in patients with healing or healed ST-elevation myocardial infarction. Am J Cardiol. 2007 Dec 15;100(12):1723-6. Epub 2007 Oct 24. PubMed PMID: 18082515. 98: Mizuno D, Kagami H, Mizuno H, Mase J, Usami K, Ueda M. Bone regeneration of dental implant dehiscence defects using a cultured periosteum membrane. Clin Oral Implants Res. 2008 Mar;19(3):289-94. Epub 2007 Dec 13. PubMed PMID: 18081869. 99: Dedecker P, Hotta J, Flors C, Sliwa M, Uji-i H, Roeffaers MB, Ando R, Mizuno H, Miyawaki A, Hofkens J. Subdiffraction imaging through the selective donut-mode depletion of thermally stable photoswitchable fluorophores: numerical analysis and application to the fluorescent protein Dronpa. J Am Chem Soc. 2007 Dec 26;129(51):16132-41. Epub 2007 Nov 30. PubMed PMID: 18047340. 100: Mizuno H, Kanai T, Kusano Y, Ko S, Ono M, Fukumura A, Abe K, Nishizawa K, Shimbo M, Sakata S, Ishikura S, Ikeda H. Feasibility study of glass dosimeter postal dosimetry audit of high-energy radiotherapy photon beams. Radiother Oncol. 2008 Feb;86(2):258-63. Epub 2007 Nov 26. PubMed PMID: 18023489. 101: Mizuno H, Ogura M, Saito Y, Sekine W, Sano R, Gotou T, Oku T, Itoh S, Katabami K, Tsuji T. Changes in adhesive and migratory characteristics of hepatocellular carcinoma (HCC) cells induced by expression of alpha3beta1 integrin. Biochim Biophys Acta. 2008 Mar;1780(3):564-70. Epub 2007 Sep 25. PubMed PMID: 17997226. 102: Mizuno H, Itoi Y, Kawahara S, Ogawa R, Akaishi S, Hyakusoku H. In vivo adipose tissue regeneration by adipose-derived stromal cells isolated from GFP transgenic mice. Cells Tissues Organs. 2008;187(3):177-85. Epub 2007 Nov 2. PubMed PMID: 17975300. 103: Flors C, Hotta J, Uji-i H, Dedecker P, Ando R, Mizuno H, Miyawaki A, Hofkens J. A stroboscopic approach for fast photoactivation-localization microscopy with Dronpa mutants. J Am Chem Soc. 2007 Nov 14;129(45):13970-7. Epub 2007 Oct 23. PubMed PMID: 17956094. 104: Mizuno H, Wu J, Katayose Y, Kanamori H, Sasaki T, Matsumoto T. Chromosome-specific distribution of nucleotide substitutions in telomeric repeats of rice (Oryza sativa L.). Mol Biol Evol. 2008 Jan;25(1):62-8. Epub 2007 Oct 16. PubMed PMID: 17940210. 105: Nakatani D, Sato H, Sakata Y, Mizuno H, Shimizu M, Suna S, Nanto S, Hirayama A, Ito H, Fujii K, Hori M. Effect of intracoronary thrombectomy on 30-day mortality in patients with acute myocardial infarction. Am J Cardiol. 2007 Oct 15;100(8):1212-7. Epub 2007 Aug 2. PubMed PMID: 17920359. 106: Mahasittiwat P, Mizoe JE, Hasegawa A, Ishikawa H, Yoshikawa K, Mizuno H, Yanagi T, Takagi R, Pattaranutaporn P, Tsujii H. l-[METHYL-(11)C] methionine positron emission tomography for target delineation in malignant gliomas: impact on results of carbon ion radiotherapy. Int J Radiat Oncol Biol Phys. 2008 Feb 1;70(2):515-22. Epub 2007 Sep 27. PubMed PMID: 17900820. 107: Waragai M, Nakai M, Wei J, Fujita M, Mizuno H, Ho G, Masliah E, Akatsu H, Yokochi F, Hashimoto M. Plasma levels of DJ-1 as a possible marker for progression of sporadic Parkinson's disease. Neurosci Lett. 2007 Sep 20;425(1):18-22. Epub 2007 Aug 11. PubMed PMID: 17720313. 108: Hayashi I, Mizuno H, Tong KI, Furuta T, Tanaka F, Yoshimura M, Miyawaki A, Ikura M. Crystallographic evidence for water-assisted photo-induced peptide cleavage in the stony coral fluorescent protein Kaede. J Mol Biol. 2007 Sep 28;372(4):918-26. Epub 2007 Jun 19. PubMed PMID: 17692334. 109: Ohnishi T, Kanoh T, Shiozaki K, Kimura Y, Iwazawa T, Tono T, Nakano Y, Yano K, Mizuno H, Shin S, Monden T. [FOLFOX 4 in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure]. Gan To Kagaku Ryoho. 2007 Aug;34(8):1299-302. Japanese. PubMed PMID: 17687218. 110: Nambu M, Ishihara M, Nakamura S, Mizuno H, Yanagibayashi S, Kanatani Y, Hattori H, Takase B, Ishizuka T, Kishimoto S, Amano Y, Yamamoto N, Azuma R, Kiyosawa T. Enhanced healing of mitomycin C-treated wounds in rats using inbred adipose tissue-derived stromal cells within an atelocollagen matrix. Wound Repair Regen. 2007 Jul-Aug;15(4):505-10. PubMed PMID: 17650094. 111: Saito H, Inagaki Y, Tsunenari T, Ura M, Mizuno H, Fujimoto-Ouchi K, Onuma E, Sato K, Ogata E, Yamada-Okabe H. Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma. Cancer Sci. 2007 Oct;98(10):1563-9. Epub 2007 Jul 23. PubMed PMID: 17645771. 112: Mizushima T, Ito T, Mizuno H, Udatsu Y, Miyazaki Y, Imakita M, Iwase K. Idiopathic granulomatous appendicitis treated surgically with long-term follow-up: report of a case. Surg Today. 2007;37(8):690-3. Epub 2007 Jul 26. PubMed PMID: 17643216. 113: Segal DL, Coolidge FL, Mizuno H. Defense mechanism differences between younger and older adults: A cross-sectional investigation. Aging Ment Health. 2007 Jul;11(4):415-22. PubMed PMID: 17612805. 114: Mizuno H, Hirano T, Tagawa Y. Evidence for activity-dependent cortical wiring: formation of interhemispheric connections in neonatal mouse visual cortex requires projection neuron activity. J Neurosci. 2007 Jun 20;27(25):6760-70. PubMed PMID: 17581963. 115: Morikawa T, Tanaka N, Kubota Y, Mizuno H, Nakamura K, Kunitomo M, Shinozuka K. ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate. Clin Exp Pharmacol Physiol. 2007 Jul;34(7):601-5. PubMed PMID: 17581215. 116: Tsuruta R, Mizuno H, Kaneko T, Oda Y, Kaneda K, Fujita M, Inoue T, Kasaoka S, Maekawa T. Preemptive therapy in nonneutropenic patients with Candida infection using the Japanese guidelines. Ann Pharmacother. 2007 Jul;41(7):1137-43. Epub 2007 May 29. PubMed PMID: 17535843. 117: Kazumoto T, Kato S, Tabushi K, Kutsutani-Nakamura Y, Mizuno H, Takahashi M, Shiromizu K, Saito Y. High dose-rate intracavitary brachytherapy for cervical carcinomas with lower vaginal infiltration. Int J Radiat Oncol Biol Phys. 2007 Nov 15;69(4):1157-66. Epub 2007 Apr 24. PubMed PMID: 17459604. 118: Takenaka Y, Yanagi A, Masuda H, Mitsui Y, Mizuno H, Haga N. Direct observation of histone H2B-YFP fusion proteins and transport of their mRNA between conjugating Paramecia. Gene. 2007 Jun 15;395(1-2):108-15. Epub 2007 Feb 28. PubMed PMID: 17408886. 119: Gopinath SC, Shikamoto Y, Mizuno H, Kumar PK. Snake-venom-derived Factor IX-binding protein specifically blocks the gamma-carboxyglutamic acid-rich-domain-mediated membrane binding of human Factors IX and X. Biochem J. 2007 Jul 15;405(2):351-7. PubMed PMID: 17407444; PubMed Central PMCID: PMC1904519. 120: Ando R, Flors C, Mizuno H, Hofkens J, Miyawaki A. Highlighted generation of fluorescence signals using simultaneous two-color irradiation on Dronpa mutants. Biophys J. 2007 Jun 15;92(12):L97-9. Epub 2007 Mar 23. PubMed PMID: 17384059; PubMed Central PMCID: PMC1877776. 121: Mizuno H, Hamada A, Shimada K, Honda H. Tropomyosin as a regulator of the sliding movement of actin filaments. Biosystems. 2007 Sep-Oct;90(2):449-55. Epub 2006 Nov 10. PubMed PMID: 17184900.