Analysis Type:	PANTHER Overrepresentation Test (Released 20210224)
Annotation Version and Release Date:	GO Ontology database DOI:  10.5281/zenodo.5080993 Released 2021-07-02
Analyzed List:	upload_1 (Homo sapiens)
Reference List:	Homo sapiens (all genes in database)
Test Type:	FISHER
Correction:	FDR
GO biological process complete	Homo sapiens - REFLIST (20595)	upload_1 (22)	upload_1 (expected)	upload_1 (over/under)	upload_1 (fold Enrichment)	upload_1 (raw P-value)	upload_1 (FDR)
heme metabolic process (GO:0042168)	41	14	.04	+	 > 100	4.79E-32	7.54E-28
porphyrin-containing compound metabolic process (GO:0006778)	48	14	.05	+	 > 100	3.19E-31	2.51E-27
tetrapyrrole metabolic process (GO:0033013)	57	14	.06	+	 > 100	2.63E-30	1.38E-26
pigment metabolic process (GO:0042440)	73	14	.08	+	 > 100	5.88E-29	2.31E-25
protoporphyrinogen IX metabolic process (GO:0046501)	11	9	.01	+	 > 100	4.48E-23	1.18E-19
heme biosynthetic process (GO:0006783)	26	10	.03	+	 > 100	4.25E-23	1.34E-19
tetrapyrrole biosynthetic process (GO:0033014)	30	10	.03	+	 > 100	1.41E-22	2.78E-19
porphyrin-containing compound biosynthetic process (GO:0006779)	30	10	.03	+	 > 100	1.41E-22	3.18E-19
protoporphyrinogen IX biosynthetic process (GO:0006782)	9	8	.01	+	 > 100	9.56E-21	1.67E-17
pigment biosynthetic process (GO:0046148)	51	10	.05	+	 > 100	1.49E-20	2.34E-17
iron ion homeostasis (GO:0055072)	82	8	.09	+	91.33	2.92E-14	4.17E-11
cellular iron ion homeostasis (GO:0006879)	64	7	.07	+	 > 100	6.94E-13	9.10E-10
transition metal ion homeostasis (GO:0055076)	135	8	.14	+	55.47	1.29E-12	1.57E-09
cellular transition metal ion homeostasis (GO:0046916)	111	7	.12	+	59.04	2.67E-11	3.00E-08
heme catabolic process (GO:0042167)	11	4	.01	+	 > 100	1.32E-09	1.30E-06
pigment catabolic process (GO:0046149)	11	4	.01	+	 > 100	1.32E-09	1.38E-06
tetrapyrrole catabolic process (GO:0033015)	12	4	.01	+	 > 100	1.75E-09	1.53E-06
porphyrin-containing compound catabolic process (GO:0006787)	12	4	.01	+	 > 100	1.75E-09	1.62E-06
heterocycle biosynthetic process (GO:0018130)	809	10	.86	+	11.57	3.88E-09	3.22E-06
aromatic compound biosynthetic process (GO:0019438)	821	10	.88	+	11.40	4.46E-09	3.51E-06
metal ion homeostasis (GO:0055065)	623	9	.67	+	13.52	7.86E-09	5.89E-06
organic cyclic compound biosynthetic process (GO:1901362)	948	10	1.01	+	9.87	1.74E-08	1.24E-05
response to platinum ion (GO:0070541)	3	3	.00	+	 > 100	2.10E-08	1.38E-05
cation homeostasis (GO:0055080)	696	9	.74	+	12.11	2.03E-08	1.39E-05
inorganic ion homeostasis (GO:0098771)	710	9	.76	+	11.87	2.40E-08	1.51E-05
heterocycle metabolic process (GO:0046483)	2624	14	2.80	+	4.99	3.56E-08	2.16E-05
ion homeostasis (GO:0050801)	759	9	.81	+	11.10	4.24E-08	2.47E-05
cellular aromatic compound metabolic process (GO:0006725)	2687	14	2.87	+	4.88	4.83E-08	2.72E-05
response to iron ion (GO:0010039)	32	4	.03	+	 > 100	5.60E-08	3.04E-05
cellular metal ion homeostasis (GO:0006875)	553	8	.59	+	13.54	6.53E-08	3.43E-05
response to arsenic-containing substance (GO:0046685)	34	4	.04	+	 > 100	7.01E-08	3.56E-05
response to metal ion (GO:0010038)	380	7	.41	+	17.24	1.04E-07	5.12E-05
organic cyclic compound metabolic process (GO:1901360)	2921	14	3.12	+	4.49	1.41E-07	6.72E-05
cellular cation homeostasis (GO:0030003)	622	8	.66	+	12.04	1.59E-07	7.37E-05
cellular ion homeostasis (GO:0006873)	639	8	.68	+	11.72	1.95E-07	8.78E-05
organonitrogen compound biosynthetic process (GO:1901566)	1249	10	1.33	+	7.50	2.29E-07	1.00E-04
cellular nitrogen compound biosynthetic process (GO:0044271)	1289	10	1.38	+	7.26	3.06E-07	1.30E-04
iron ion transport (GO:0006826)	52	4	.06	+	72.01	3.44E-07	1.43E-04
cellular nitrogen compound metabolic process (GO:0034641)	3192	14	3.41	+	4.11	4.34E-07	1.75E-04
cellular chemical homeostasis (GO:0055082)	742	8	.79	+	10.09	6.01E-07	2.36E-04
chemical homeostasis (GO:0048878)	1114	9	1.19	+	7.56	1.07E-06	4.10E-04
response to inorganic substance (GO:0010035)	554	7	.59	+	11.83	1.27E-06	4.77E-04
cellular homeostasis (GO:0019725)	833	8	.89	+	8.99	1.42E-06	5.21E-04
homeostatic process (GO:0042592)	1556	10	1.66	+	6.02	1.72E-06	6.15E-04
transition metal ion transport (GO:0000041)	100	4	.11	+	37.45	4.17E-06	1.46E-03
heme oxidation (GO:0006788)	2	2	.00	+	 > 100	6.51E-06	2.23E-03
organonitrogen compound metabolic process (GO:1901564)	4789	15	5.12	+	2.93	9.79E-06	3.28E-03
regulation of succinate dehydrogenase activity (GO:1904229)	3	2	.00	+	 > 100	1.08E-05	3.35E-03
positive regulation of succinate dehydrogenase activity (GO:1904231)	3	2	.00	+	 > 100	1.08E-05	3.41E-03
regulation of aconitate hydratase activity (GO:1904232)	3	2	.00	+	 > 100	1.08E-05	3.48E-03
positive regulation of aconitate hydratase activity (GO:1904234)	3	2	.00	+	 > 100	1.08E-05	3.56E-03
hemoglobin biosynthetic process (GO:0042541)	6	2	.01	+	 > 100	3.03E-05	9.00E-03
intracellular sequestering of iron ion (GO:0006880)	6	2	.01	+	 > 100	3.03E-05	9.18E-03
sequestering of iron ion (GO:0097577)	7	2	.01	+	 > 100	3.90E-05	1.11E-02
response to methylmercury (GO:0051597)	7	2	.01	+	 > 100	3.90E-05	1.14E-02
cellular biosynthetic process (GO:0044249)	2293	10	2.45	+	4.08	5.38E-05	1.51E-02
organic substance biosynthetic process (GO:1901576)	2354	10	2.51	+	3.98	6.75E-05	1.86E-02
hemoglobin metabolic process (GO:0020027)	10	2	.01	+	 > 100	7.13E-05	1.93E-02
biosynthetic process (GO:0009058)	2420	10	2.59	+	3.87	8.56E-05	2.28E-02
sequestering of metal ion (GO:0051238)	12	2	.01	+	 > 100	9.81E-05	2.57E-02
erythrocyte homeostasis (GO:0034101)	95	3	.10	+	29.56	1.50E-04	3.88E-02