Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.14861039 Released 2025-02-06 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: BONFERRONI Bonferroni count: 8995 GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (61) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (P-value) Unclassified (UNCLASSIFIED) 2879 7 8.53 - .82 0.00E00 glycosphingolipid metabolic process (GO:0006687) 64 36 .19 + > 100 1.71E-75 sphingolipid metabolic process (GO:0006665) 163 42 .48 + 86.93 4.23E-72 membrane lipid metabolic process (GO:0006643) 209 42 .62 + 67.80 5.49E-67 glycolipid metabolic process (GO:0006664) 107 36 .32 + > 100 5.62E-65 liposaccharide metabolic process (GO:1903509) 108 36 .32 + > 100 8.43E-65 ceramide metabolic process (GO:0006672) 99 32 .29 + > 100 4.38E-56 sphingolipid catabolic process (GO:0030149) 42 22 .12 + > 100 1.43E-42 membrane lipid catabolic process (GO:0046466) 48 22 .14 + > 100 7.52E-41 glycosphingolipid catabolic process (GO:0046479) 18 17 .05 + > 100 1.46E-39 sphingolipid biosynthetic process (GO:0030148) 106 25 .31 + 79.57 2.02E-38 glycolipid catabolic process (GO:0019377) 21 17 .06 + > 100 4.82E-37 lipid metabolic process (GO:0006629) 1209 44 3.58 + 12.28 5.94E-37 amide metabolic process (GO:0043603) 408 33 1.21 + 27.29 1.82E-36 glycosphingolipid biosynthetic process (GO:0006688) 39 19 .12 + > 100 2.41E-35 membrane lipid biosynthetic process (GO:0046467) 145 25 .43 + 58.17 1.15E-34 ganglioside metabolic process (GO:0001573) 29 17 .09 + > 100 4.11E-33 ceramide catabolic process (GO:0046514) 21 15 .06 + > 100 8.88E-31 carbohydrate derivative metabolic process (GO:1901135) 898 36 2.66 + 13.53 1.53E-29 ceramide biosynthetic process (GO:0046513) 58 18 .17 + > 100 7.22E-29 glycolipid biosynthetic process (GO:0009247) 78 19 .23 + 82.18 2.17E-28 oligosaccharide metabolic process (GO:0009311) 64 17 .19 + 89.62 1.02E-25 carbohydrate metabolic process (GO:0005975) 447 26 1.32 + 19.62 1.51E-23 lipid catabolic process (GO:0016042) 304 23 .90 + 25.53 6.95E-23 lipid biosynthetic process (GO:0008610) 583 27 1.73 + 15.62 5.17E-22 amide biosynthetic process (GO:0043604) 155 18 .46 + 39.18 1.97E-20 ganglioside catabolic process (GO:0006689) 8 8 .02 + > 100 3.32E-17 carbohydrate derivative catabolic process (GO:1901136) 201 17 .60 + 28.53 1.12E-16 glycosylceramide metabolic process (GO:0006677) 15 9 .04 + > 100 4.23E-16 glycoprotein metabolic process (GO:0009100) 346 19 1.03 + 18.53 1.66E-15 glycosylation (GO:0070085) 236 17 .70 + 24.30 1.77E-15 ganglioside biosynthetic process (GO:0001574) 17 9 .05 + > 100 2.04E-15 carbohydrate catabolic process (GO:0016052) 124 13 .37 + 35.37 3.35E-13 carbohydrate derivative biosynthetic process (GO:1901137) 553 20 1.64 + 12.20 5.53E-13 protein glycosylation (GO:0006486) 215 14 .64 + 21.97 1.58E-11 macromolecule glycosylation (GO:0043413) 215 14 .64 + 21.97 1.58E-11 oligosaccharide biosynthetic process (GO:0009312) 27 8 .08 + 99.96 7.06E-11 oligosaccharide catabolic process (GO:0009313) 16 7 .05 + > 100 1.42E-10 catabolic process (GO:0009056) 2013 29 5.97 + 4.86 3.76E-10 glycoprotein biosynthetic process (GO:0009101) 279 14 .83 + 16.93 5.86E-10 metabolic process (GO:0008152) 7621 51 22.59 + 2.26 8.18E-10 primary metabolic process (GO:0044238) 6774 48 20.08 + 2.39 2.37E-09 glycosylceramide catabolic process (GO:0046477) 6 5 .02 + > 100 1.04E-08 sphingomyelin catabolic process (GO:0006685) 5 4 .01 + > 100 3.13E-06 glucosylceramide metabolic process (GO:0006678) 5 4 .01 + > 100 3.13E-06 ganglioside biosynthetic process via lactosylceramide (GO:0010706) 6 4 .02 + > 100 9.38E-06 sphingomyelin metabolic process (GO:0006684) 18 5 .05 + 93.72 1.45E-05 glycoside catabolic process (GO:0016139) 7 4 .02 + > 100 2.18E-05 carbohydrate biosynthetic process (GO:0016051) 123 8 .36 + 21.94 2.63E-05 galactosylceramide metabolic process (GO:0006681) 8 4 .02 + > 100 4.36E-05 hexose catabolic process (GO:0019320) 49 6 .15 + 41.31 6.00E-05 nutrient storage (GO:0170062) 50 6 .15 + 40.49 6.80E-05 lipid storage (GO:0019915) 50 6 .15 + 40.49 6.80E-05 galactose catabolic process (GO:0019388) 9 4 .03 + > 100 7.83E-05 galactolipid metabolic process (GO:0019374) 9 4 .03 + > 100 7.83E-05 monosaccharide catabolic process (GO:0046365) 53 6 .16 + 38.19 9.76E-05 glucosylceramide catabolic process (GO:0006680) 3 3 .01 + > 100 2.23E-04 lipid glycosylation (GO:0030259) 12 4 .04 + > 100 3.05E-04 galactose metabolic process (GO:0006012) 13 4 .04 + > 100 4.40E-04 glycoprotein catabolic process (GO:0006516) 36 5 .11 + 46.86 6.11E-04 myelination (GO:0042552) 131 7 .39 + 18.03 1.06E-03 biosynthetic process (GO:0009058) 3960 30 11.74 + 2.56 1.16E-03 ensheathment of neurons (GO:0007272) 133 7 .39 + 17.76 1.18E-03 axon ensheathment (GO:0008366) 133 7 .39 + 17.76 1.18E-03 glycoside metabolic process (GO:0016137) 19 4 .06 + 71.03 2.36E-03 protein O-linked glycosylation (GO:0006493) 97 6 .29 + 20.87 3.80E-03 glycosylceramide biosynthetic process (GO:0046476) 7 3 .02 + > 100 7.73E-03 glycosyl compound catabolic process (GO:1901658) 26 4 .08 + 51.90 8.94E-03