MARGARITA VOROBEVA



Bifunctional protein MdtA

Table 1. Protein information
UniProt ID MTDA_METEA
UniProt AC P55818
RefSeq ID WP_003597637.1
PDB ID 1LU9
Length, AA 288
Total Molecular Weight, Da 29,736
RecName Bifunctional protein MdtA
This protein is built out of 3 chains: A, B and C, from which the amount of unique is one; RecName of this protein is Bifunctional protein MdtA. It includes: NADP-dependent methylenetetrahydromethanopterin dehydrogenase and Methylenetetrahydrofolate dehydrogenase

Table 2. Protein sequence

     MSKKLLFQFD TDATPSVFDV VVGYDGGADH ITGYGNVTPD NVGAYVDGTI YTRGGKEKQS
     TAIFVGGGDM AAGERVFEAV KKRFFGPFRV SCMLDSNGSN TTAAAGVALV VKAAGGSVKG
     KKAVVLAGTG PVGMRSAALL AGEGAEVVLC GRKLDKAQAA ADSVNKRFKV NVTAAETADD
     ASRAEAVKGA HFVFTAGAIG LELLPQAAWQ NESSIEIVAD YNAQPPLGIG GIDATDKGKE
     YGGKRAFGAL GIGGLKLKLH RACIAKLFES SEGVFDAEEI YKLAKEMA
      

UniProt Clusters

UniRef100: cluster ID is UniRef100_P55818, it contains 7 proteins. The review showed that this proteins also belongs to Methylobacteriaceae family.

UniRef90: cluster ID is UniRef90_P55818, it contains 15 proteins.

UniRef50: cluster ID is UniRef50_P55818, it contains 24 proteins.

(not including the given protein)

UniProt Search queries

Basic information about search queries is presented in Table 3.

Query 'name:Bifunctional protein MdtA ' (Table 3, line 1): proteins from such popular organisms were found: Crenothrix polyspora, Methylomicrobium alcaliphilum (strain DSM 19304 / NCIMB 14124 / VKM B-2133 / 20Z), Methylobacterium radiotolerans.

Table 3. Search queries info
Search query Total amount of proteins Reviewed proteins Description
name: Bifunctional protein MdtA 27 1 Query by recommended name
name:Bifunctional protein MdtA; organism: Methylobacterium extorquens 1 1 Query by recommended name and organism
name:Bifunctional protein MdtA; organism family: Methylobacteriaceae 2 1 Query by recommended name and organism family
name: Bifunctional protein MdtA; phylum: Proteobacteria 16 1 Query by recommended name and organism phylum
name: Cytochrome 1,949,597 7,619 Cytochrome in all groups of animals
name: Cytochrome; taxonomy:Vertebrata 285,172 2,932 Cytochrome in Vertebrata
name: Cytochrome; taxonomy:Phaeophyceae 3,023 3 Cytochrome in Phaeophyceae
name: trypsin 18,951 311 Trypsin in all groups of animals
name: trypsin; name: inhibitor 3,914 210 Trypsin inhibitors in all groups of animals

History

The whole history of Bifunctional protein MdtA changes is presented in Figure 1. As we can see, the first record was made on 1997-11-01 and it is regularly updated (108 times) until now (last change was made on 2018-02-28).

Figure 1 MdtA changes history

MdtA in RefSeq database

According to Table 1, MdtA has WP_003597637.1 identifier in RefSeq Protein database. This data contains only main details about the protein: there is no helices, turns or strands information presented. There is also no information about references in publications in different databases available.