>WP_314124025.1/1-539 DEAD/DEAH box helicase [Saccharolobus sp.]
---------------------------MFSKTFYIKQ-------------WIDDE-------SFRKLLLFSR
--------YLGRDYNGSQFMI------DLDR----------------------ARRNGIKAKDIIEILEEFN
IKLSQDDLNVLK----------------------KELLDASFEIVS--GKIFLK--PYIYLA-DFLK---DF
PVKYDKVNK---------------------RFIIRPMDYFDILQKLKENGLEVNE----LELTFKDFEF-EF
IGQLREYQKEAIDAWVSNKNRGVIALPTGSGKTVVGIKAIELVKKPTLIITFTKEQMMQWKDSIIKFTSKRP
D-IGLYYSEEKKIRPITITTYHTAYRH--IAELFDKFYFLIIDEAHHLPAEKFKAIAEGLISPYRMGLSATP
YREDGKHEELFRLVGGVIYYKSAYELAKLGYLA--PYEIIQRKVRLTPDERKKYNELLNKFKNLSRGKKVSE
LIQLVKQGDEKAIEAMKIYNEMKKIVNFASEKMRAVDEILKTE--KG-KILIFTQYVDQAEEIA----KRYN
ALLLTGKMSKEE---RRRVLNTFKNMSSGVLVLTTVGDEGIDIPDANIGIIVTGTGSRRQFIQRLGRILRPY
QGKQ-AKLYEIIVSGTAEEYQARKRKESDILSFNVYETSSEDFDSI---------------
>MCC6060759.1/1-531 DEAD/DEAH box helicase [Desulfurococcaceae archaeon]
------------------------------MRFRVKG-------------WIGDD-------EFRELLEFSR
--------YIGRVGGVSVFEL------DPLK----------------------MRSNGYTLGDVYSKLSSI-
EGVVEEDLKAIR----------------------DAYLEESVVYVRLGGDGFLRVSSRAYLK-GFFEKHG-F
TPPYSPSER---------------------AFKIPPHLYGDVVVKLEREGFNVVDEVGLLKSSRLPRDL-VF
SGELRDYQREALEAWERNGFKGVIALPTGSGKTVVALAGVAKLSVKTLVVVYTKDHIKQWAEAFRRFTGASG
I-IGMYYGEEKSLNPITITTYQSAFRN--VVEFARHFALLVFDEAHHLPAEKFKHIAFSMPAPYRMALSATP
EREDGKHVEIFPLIGGVIYFKSASELAEKGYLA--PFTLKRIKVRLTGEEWKHYEELRRRFLLLAEGRRFQE
LVEDAKRGDRNAVEALKIHAEMRNIINYSESKLKAVEEKVREELSKGGKIIVFTQYKGQAEEIA----SRVK
GLLLHGELSESE---RERVLRAFKTAKTGVLVVTTVGDEGLDIPDANIGILVSGTSSRRQFIQRLGRLLRPT
PGKT-AILYEIITAGTSEEYQARKRKELL--------------------------------
>WP_277025443.1/1-662 DEAD/DEAH box helicase [Pyrobaculum aerophilum]
MGLNMKLLLNVPRFVVAVNGIEIVREWPWERILRVKEELKRLGFRWDGASWRGKTRDVAMIARLRQLLELNN
EEYLSILSSVGKSHGGGSIVVIGALPAELEQHVLASEGNAHVISLTGYLRRFIAEDKSISKASTFEEFVELG
INRLRELLRGVEIWGELEKALNEAREFILASEKMKTLFEKRRSWRK--AVIGLNYAKLNFLASGLLKRIGEF
KLKYNVVNKDGELIEHNIKLVHLVQESGGYKLVFPVFIRERVVKTLEELGYVIQY----ESAEYPRVSY-KK
GFSLLPFQVEAVENWTSHGMRGTVIIPTGGGKTFVGLEAMYRAGTSAIVLVVTKELAAQWAERIRKYLGVSP
---GVLGGGYKEVRDVTVAIYNSAVKH--IDELRGRFGLVIFDEAHHVPAETFKEVALSLESPFRLALSATP
EREDQNEHLIYEAVGPPVYRASYRSMIEAGLVV--PVEHYRIYVRMSREEEALYASLPQNNAIV--------
---------------------LRNAAAKASKKIPIAVRVVVQEVALGSKVLVFTQFIDQAEELY----KRLR
ESGIAAELITSEEGNREAAFRRFSNGLSKVVVTTTVLDEGVDVPDAEVAVIVSGTGSRRQMIQRVGRVVRAT
AGKRAARVYEIITRNTIEEALSEARHFDDVVEEAICKRLSEADLDSYLGKLAPLSPWLKKN
>NQV37212.1/1-466 DEAD/DEAH box helicase [Candidatus Neomarinimicrobiota bacterium]
---------------------------------------------------------------MKAILN---
-----------------------------------------------------ASVQIIKETTPQKILHHIR
EDLTYPNPEFTQ--------------------------KARFDY---------------YLG-DTSKTIKSY
EDDAE-------------------------YLTVPRGYAYPLIKLAEKQQFKIDWED--LRISHPNTIITDS
DFTLRDYQIKAKEAFIKREQ-GVIVVPCGGGKTIVAMSIMDEVKEPTLIIVHTIDLLNQWVDNLKEKLGIEN
--IGIISGPTNTLENVTVSTIQSLRNHPNLTQLSTDFGMVILDEAHHVPADTFRKVLNQFQSKYRLGLSATP
NRADGLTDILYHTIGRKVYEVDYPYLIDNGFLIKPTYKVIRTGFDFNPQKQTPSGRMILDWHRM--------
---------------------AKHLISQP-TRNELIYSVIFKTHTRGELALILSGRVDHLKMMYGTLKDKYR
CAILIGATKKKE---RIEILKKARAEELDILFSANVSDEGLDMPNLKRVYLTFPNKSESKVIQRIGRILRPY
PDKTSAEVYDFV-DDKVPALVSQARQRINIFKKTFGSYTNGEF------------------
>HDJ94908.1/1-549 DEAD/DEAH box helicase [Acidilobales archaeon]
--------------------MITWSERALSIYFEVKK-------------WLDKE-------DYEKLLTIAD
--------YLGRTNRGAKFVI------NFNK----------------------IHKSNLEYEDVISILEDIG
IALNEKILEKIK-------------------ERILEKRTVRLIWDQ--NRVLLQ--THIYLG-EKFNKIRDF
-VTYDRRLR---------------------KIYVKPIYFFELKKKLNELGLRVIDETGLSDSLKLPFNI-KL
NVTLRDYQKEALNTWLNKGAKGVIALPTGAGKTIIAIAAMAKLSERTLIVTYTKEQMFQWQDMIVKFTDVKK
EYIGLYYGEEKRLSPITISTYQTAYRH--IDVLTKYFSFLIIDEVHHLPSDKFKYIAINSFAPKRMGLSATV
VREDGKHEELFPLMGGVVYYKSPSDLAIKGYLA--PYIIYPIEVALTPDEYKEYRELYKMYKELSGGEKFEM
ILEKARRGDIRAQNALRIHSKLRQIVHKSKSKNKVVRKIVDLELKKGSKIIVFTQYVDQAKELG----VLLN
APILIGETETRK---RQEILRDFKEGKTRVLVVTTVGDEGLDIPDANVGIIVTGTGSRRQFIQRLGRLLRPS
EGKE-ARLYEIIVKGTLEEFQSRRRKSFDLSELLFK-------------------------
>NON61800.1/1-533 DEAD/DEAH box helicase [Acidianus sp. RZ1]
---------------------------MFLKTFYLKQ-------------WIDED-------TFSRLLTFSR
--------FLGRDDGVSQFAI------DLDR----------------------ARLNGVKIDDIESTLKELG
IQLSTEELEKIR--------------------NHIPSYDVEFEVRQ--GRLIII--PHVYIM-NILKAKSNT
DIKYDKLTK---------------------YFFSSPYYYEDLLKLFEENGLRVRK----LQVEHKDFDF-EL
DVNLRSYQIEAVEAWKSNNFRGVISLPTGSGKTIIGIKAIEEVKKPTLIISFTKEQMFQWRDSIIKFSKIRP
E-IGLFYSDEKVIRPITISTYQTAYRH--LDDLSTKFEVLIIDEVHHLPADKFKNIALGLISSMRLGLSATP
YRDDGRHDELFRLMGGLIYYKSPNDLIKTGYLA--PYDVIQVSVYLSKTERQRYKDLTNKFRVFSKGKRVTD
LVTLAKNGDYNAINALKIYSEIKKLIGNAENKTVKLREILEKE--KGKKILIFTQYVEQAESIA----REFN
AMLVTGKMIKSD---RKEILKRFKTSAEGRLVLTTVGDEGLDIPDASVGIIVTGTSSRRQFIQRLGRLLRPM
NGKR-AILYELIVKGTSEEYQAKKRKTESLLEEL---------------------------
