Analysis Type:	PANTHER Overrepresentation Test (Released 20240807)
Annotation Version and Release Date:	GO Ontology database DOI:  10.5281/zenodo.14861039 Released 2025-02-06
Analyzed List:	upload_1 (Homo sapiens)
Reference List:	Homo sapiens (all genes in database)
Test Type:	FISHER
Correction:	FDR
GO biological process complete	Homo sapiens - REFLIST (20580)	upload_1 (29)	upload_1 (expected)	upload_1 (over/under)	upload_1 (fold Enrichment)	upload_1 (raw P-value)	upload_1 (FDR)
sterol biosynthetic process (GO:0016126)	44	24	.06	+	 > 100	3.93E-63	5.84E-59
cholesterol biosynthetic process (GO:0006695)	37	23	.05	+	 > 100	4.67E-62	2.32E-58
secondary alcohol biosynthetic process (GO:1902653)	37	23	.05	+	 > 100	4.67E-62	3.47E-58
cholesterol metabolic process (GO:0008203)	120	26	.17	+	 > 100	1.60E-56	5.94E-53
sterol metabolic process (GO:0016125)	131	26	.18	+	 > 100	2.03E-55	6.04E-52
secondary alcohol metabolic process (GO:1902652)	132	26	.19	+	 > 100	2.53E-55	6.27E-52
steroid biosynthetic process (GO:0006694)	97	24	.14	+	 > 100	7.64E-53	1.62E-49
alcohol biosynthetic process (GO:0046165)	96	23	.14	+	 > 100	6.46E-50	1.20E-46
steroid metabolic process (GO:0008202)	257	26	.36	+	71.79	3.13E-47	5.18E-44
alcohol metabolic process (GO:0006066)	314	26	.44	+	58.76	7.25E-45	1.08E-41
lipid biosynthetic process (GO:0008610)	583	25	.82	+	30.43	2.60E-35	3.52E-32
lipid metabolic process (GO:0006629)	1209	28	1.70	+	16.44	6.92E-34	8.58E-31
small molecule biosynthetic process (GO:0044283)	465	23	.66	+	35.10	3.39E-33	3.87E-30
small molecule metabolic process (GO:0044281)	1575	27	2.22	+	12.17	2.07E-28	2.20E-25
isoprenoid biosynthetic process (GO:0008299)	28	10	.04	+	 > 100	6.91E-23	6.85E-20
isoprenoid metabolic process (GO:0006720)	122	12	.17	+	69.80	5.16E-20	4.79E-17
isopentenyl diphosphate metabolic process (GO:0046490)	5	5	.01	+	 > 100	3.86E-15	3.19E-12
isopentenyl diphosphate biosynthetic process (GO:0009240)	5	5	.01	+	 > 100	3.86E-15	3.38E-12
biosynthetic process (GO:0009058)	3960	25	5.58	+	4.48	1.26E-14	9.90E-12
farnesyl diphosphate metabolic process (GO:0045338)	6	5	.01	+	 > 100	2.31E-14	1.72E-11
primary metabolic process (GO:0044238)	6774	28	9.55	+	2.93	5.86E-13	4.15E-10
cholesterol biosynthetic process via desmosterol (GO:0033489)	4	4	.01	+	 > 100	3.18E-12	2.06E-09
cholesterol biosynthetic process via lathosterol (GO:0033490)	4	4	.01	+	 > 100	3.18E-12	2.15E-09
metabolic process (GO:0008152)	7621	28	10.74	+	2.61	1.50E-11	9.32E-09
phospholipid metabolic process (GO:0006644)	356	10	.50	+	19.93	3.16E-11	1.88E-08
phospholipid biosynthetic process (GO:0008654)	230	8	.32	+	24.68	7.55E-10	4.32E-07
geranyl diphosphate metabolic process (GO:0033383)	3	3	.00	+	 > 100	2.52E-09	1.34E-06
isopentenyl diphosphate biosynthetic process, mevalonate pathway (GO:0019287)	3	3	.00	+	 > 100	2.52E-09	1.39E-06
terpenoid biosynthetic process (GO:0016114)	14	4	.02	+	 > 100	3.15E-09	1.62E-06
terpenoid metabolic process (GO:0006721)	102	6	.14	+	41.74	5.53E-09	2.74E-06
farnesyl diphosphate biosynthetic process (GO:0045337)	4	3	.01	+	 > 100	1.01E-08	4.82E-06
organophosphate metabolic process (GO:0019637)	975	11	1.37	+	8.01	4.02E-08	1.87E-05
acetyl-CoA metabolic process (GO:0006084)	29	4	.04	+	97.88	7.37E-08	3.32E-05
organophosphate biosynthetic process (GO:0090407)	565	8	.80	+	10.05	7.92E-07	3.47E-04
dimethylallyl diphosphate biosynthetic process (GO:0050992)	2	2	.00	+	 > 100	1.92E-06	7.50E-04
dimethylallyl diphosphate metabolic process (GO:0050993)	2	2	.00	+	 > 100	1.92E-06	7.71E-04
geranyl diphosphate biosynthetic process (GO:0033384)	2	2	.00	+	 > 100	1.92E-06	7.92E-04
geranylgeranyl diphosphate metabolic process (GO:0033385)	2	2	.00	+	 > 100	1.92E-06	8.15E-04
phosphorus metabolic process (GO:0006793)	1462	11	2.06	+	5.34	2.34E-06	8.71E-04
phosphate-containing compound metabolic process (GO:0006796)	1459	11	2.06	+	5.35	2.30E-06	8.76E-04
thioester metabolic process (GO:0035383)	92	4	.13	+	30.85	8.15E-06	2.89E-03
acyl-CoA metabolic process (GO:0006637)	92	4	.13	+	30.85	8.15E-06	2.96E-03
regulation of cholesterol metabolic process (GO:0090181)	42	3	.06	+	50.69	2.78E-05	9.63E-03
negative regulation of amyloid-beta clearance (GO:1900222)	9	2	.01	+	 > 100	6.86E-05	2.27E-02
SREBP signaling pathway (GO:0032933)	9	2	.01	+	 > 100	6.86E-05	2.32E-02
sulfur compound metabolic process (GO:0006790)	317	5	.45	+	11.19	7.36E-05	2.38E-02
cellular response to sterol depletion (GO:0071501)	10	2	.01	+	 > 100	8.57E-05	2.71E-02
negative regulation of protein secretion (GO:0050709)	68	3	.10	+	31.31	1.19E-04	3.67E-02
regulation of ferroptosis (GO:0110075)	12	2	.02	+	 > 100	1.25E-04	3.73E-02
response to sterol depletion (GO:0006991)	12	2	.02	+	 > 100	1.25E-04	3.81E-02