Analysis Type: PANTHER Overrepresentation Test (Released 20240807) Annotation Version and Release Date: GO Ontology database DOI: 10.5281/zenodo.15066566 Released 2025-03-16 Analyzed List: upload_1 (Homo sapiens) Reference List: Homo sapiens (all genes in database) Test Type: FISHER Correction: FDR GO biological process complete Homo sapiens - REFLIST (20580) upload_1 (51) upload_1 (expected) upload_1 (over/under) upload_1 (fold Enrichment) upload_1 (raw P-value) upload_1 (FDR) glycosaminoglycan metabolic process (GO:0030203) 77 29 .19 + > 100 1.44E-59 2.13E-55 proteoglycan metabolic process (GO:0006029) 106 30 .26 + > 100 2.60E-57 1.93E-53 aminoglycan metabolic process (GO:0006022) 92 29 .23 + > 100 7.61E-57 2.82E-53 chondroitin sulfate proteoglycan metabolic process (GO:0050654) 30 23 .07 + > 100 6.42E-57 3.17E-53 chondroitin sulfate proteoglycan biosynthetic process (GO:0050650) 24 19 .06 + > 100 2.78E-47 8.23E-44 glycosaminoglycan biosynthetic process (GO:0006024) 40 21 .10 + > 100 1.98E-46 4.88E-43 proteoglycan biosynthetic process (GO:0030166) 78 24 .19 + > 100 3.20E-46 6.77E-43 aminoglycan biosynthetic process (GO:0006023) 48 21 .12 + > 100 3.32E-44 6.15E-41 glycoprotein metabolic process (GO:0009100) 348 30 .86 + 34.79 1.64E-40 2.70E-37 dermatan sulfate proteoglycan metabolic process (GO:0050655) 13 13 .03 + > 100 2.51E-35 3.71E-32 sulfur compound metabolic process (GO:0006790) 314 26 .78 + 33.41 3.65E-34 4.91E-31 glycoprotein biosynthetic process (GO:0009101) 281 24 .70 + 34.47 1.08E-31 1.33E-28 carbohydrate derivative metabolic process (GO:1901135) 895 32 2.22 + 14.43 3.45E-31 3.93E-28 sulfur compound biosynthetic process (GO:0044272) 149 20 .37 + 54.17 2.68E-30 2.83E-27 carbohydrate derivative biosynthetic process (GO:1901137) 556 25 1.38 + 18.14 4.67E-26 4.62E-23 dermatan sulfate proteoglycan biosynthetic process (GO:0050651) 9 9 .02 + > 100 1.67E-24 1.55E-21 carbohydrate metabolic process (GO:0005975) 442 18 1.10 + 16.43 9.76E-18 8.50E-15 heparan sulfate proteoglycan metabolic process (GO:0030201) 42 9 .10 + 86.47 7.01E-16 5.77E-13 glycosaminoglycan catabolic process (GO:0006027) 26 7 .06 + > 100 2.37E-13 1.85E-10 aminoglycan catabolic process (GO:0006026) 32 7 .08 + 88.27 1.20E-12 8.89E-10 proteoglycan catabolic process (GO:0030167) 17 6 .04 + > 100 2.07E-12 1.46E-09 protein metabolic process (GO:0019538) 3342 30 8.28 + 3.62 6.08E-12 4.10E-09 dermatan sulfate proteoglycan catabolic process (GO:0030209) 4 4 .01 + > 100 3.34E-11 2.15E-08 heparan sulfate proteoglycan biosynthetic process (GO:0015012) 30 6 .07 + 80.71 9.69E-11 5.98E-08 hyaluronan catabolic process (GO:0030214) 16 5 .04 + > 100 3.27E-10 1.94E-07 glycoprotein catabolic process (GO:0006516) 37 6 .09 + 65.44 3.75E-10 2.13E-07 skeletal system development (GO:0001501) 514 12 1.27 + 9.42 3.40E-09 1.86E-06 macromolecule biosynthetic process (GO:0009059) 2937 25 7.28 + 3.43 3.71E-09 1.96E-06 hyaluronan metabolic process (GO:0030212) 28 5 .07 + 72.06 7.19E-09 3.67E-06 carbohydrate biosynthetic process (GO:0016051) 116 7 .29 + 24.35 1.42E-08 7.01E-06 carbohydrate derivative catabolic process (GO:1901136) 207 8 .51 + 15.60 4.02E-08 1.92E-05 cell migration (GO:0016477) 941 14 2.33 + 6.00 4.21E-08 1.95E-05 macromolecule metabolic process (GO:0043170) 5404 32 13.39 + 2.39 4.65E-08 2.09E-05 sulfur compound catabolic process (GO:0044273) 47 5 .12 + 42.93 1.08E-07 4.72E-05 biosynthetic process (GO:0009058) 3997 26 9.91 + 2.62 4.32E-07 1.83E-04 cell motility (GO:0048870) 1172 14 2.90 + 4.82 6.20E-07 2.55E-04 heparan sulfate proteoglycan catabolic process (GO:0030200) 10 3 .02 + > 100 1.70E-06 6.81E-04 amino sugar metabolic process (GO:0006040) 43 4 .11 + 37.54 3.84E-06 1.46E-03 primary metabolic process (GO:0044238) 6778 33 16.80 + 1.96 3.77E-06 1.47E-03 cartilage development (GO:0051216) 179 6 .44 + 13.53 5.18E-06 1.92E-03 heparin proteoglycan metabolic process (GO:0030202) 17 3 .04 + 71.21 9.51E-06 3.44E-03 regulation of protein localization to membrane (GO:1905475) 201 6 .50 + 12.05 1.01E-05 3.55E-03 N-acetylglucosamine metabolic process (GO:0006044) 19 3 .05 + 63.72 1.35E-05 4.65E-03 metabolic process (GO:0008152) 7642 34 18.94 + 1.80 2.81E-05 9.46E-03 connective tissue development (GO:0061448) 244 6 .60 + 9.92 3.01E-05 9.91E-03 positive regulation of extracellular exosome assembly (GO:1903553) 4 2 .01 + > 100 3.60E-05 1.11E-02 chondroitin sulfate proteoglycan catabolic process (GO:0030207) 4 2 .01 + > 100 3.60E-05 1.14E-02 glucosamine-containing compound metabolic process (GO:1901071) 26 3 .06 + 46.56 3.58E-05 1.15E-02 system development (GO:0048731) 3629 21 8.99 + 2.34 6.90E-05 2.09E-02 regulation of extracellular exosome assembly (GO:1903551) 6 2 .01 + > 100 8.97E-05 2.66E-02 ganglioside catabolic process (GO:0006689) 8 2 .02 + > 100 1.67E-04 4.85E-02